Term IRI Term label Parent term IRI Parent term label Alternative term Definition http://purl.obolibrary.org/obo/CL_4052047 late luteal cell http://purl.obolibrary.org/obo/CL_0000175 luteal cell A luteal cell that is part of the older, regressing corpus luteum. This cell exhibits increased expression of genes involved in progesterone metabolism - Akr1c18 in mice (Lan et al., 2024), cell cycle arrest, and apoptosis. A late luteal cell contributes to corpus luteum regression and eventual clearance from the ovary through luteolysis. http://purl.obolibrary.org/obo/GO_0098691 dopaminergic synapse http://purl.obolibrary.org/obo/GO_0045202 synapse A synapse that uses dopamine as a neurotransmitter. http://purl.obolibrary.org/obo/CL_4052050 luminal epithelial cell of endometrium http://purl.obolibrary.org/obo/CL_0002149 epithelial cell of uterus An epithelial cell that is part of an endometrium luminal epithelium. http://purl.obolibrary.org/obo/GO_0099140 presynaptic actin cytoskeleton organization http://purl.obolibrary.org/obo/GO_0099187 presynaptic cytoskeleton organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins in the presynaptic actin cytoskeleton. http://purl.obolibrary.org/obo/GO_0099143 presynaptic actin cytoskeleton http://purl.obolibrary.org/obo/GO_0015629 actin cytoskeleton The actin cytoskeleton that is part of a presynapse. http://purl.obolibrary.org/obo/CL_4052051 uterine natural killer cell 1, human http://purl.obolibrary.org/obo/CL_4052028 uterine natural killer cell ​​A uterine natural killer subset that is present in the endometrial lining during the non-pregnant state (Garcia-Alonso et al., 2021) and in the decidua during pregnancy (Vento-Tormo et al., 2018). It expresses the uterine resident marker CD49a and is distinguished from uNK2 and uNK3 by CD39 expression and the absence of CD103 (Whettlock et al., 2022) and CD160 (Marečková et al., 2024). It also expresses higher levels of killer-cell immunoglobulin-like receptors (KIRs) and leukocyte immunoglobulin-like receptor B1 (LILRB1), which facilitate interaction with human leukocyte antigens (HLAs) on extravillous trophoblast cells, promoting immune tolerance and implantation. Enriched in the endometrium post-ovulation (Marečková et al., 2024) and prominent in early pregnancy (Whettlock et al., 2022), uNK1 regulates trophoblast invasion and spiral artery remodeling (Zhang & Wei, 2021). http://purl.obolibrary.org/obo/GO_0099145 regulation of exocytic insertion of neurotransmitter receptor to postsynaptic membrane http://purl.obolibrary.org/obo/GO_1904375 regulation of protein localization to cell periphery Any process that modulates the frequency, rate or extent of exocytic fusion of neurotransmitter receptor containing vesicles into the postsynaptic membrane. http://purl.obolibrary.org/obo/CL_4052052 uterine natural killer cell 2, human http://purl.obolibrary.org/obo/CL_4052028 uterine natural killer cell A uterine natural killer subset that is present in the endometrial lining during the non-pregnant state (Garcia-Alonso et al., 2021) and in the decidua during pregnancy (Vento-Tormo et al., 2018), peaking in the first trimester. It expresses the uterine resident marker CD49a and is distinguished from uNK1 and uNK3 by the absence of CD39, CD103 (Whettlock et al., 2022), and CD160 (Marečková et al., 2024), with ITGB2 serving as a defining marker (Vento-Tormo et al., 2018). Functionally, it produces more cytokines upon stimulation than uNK1, suggesting a role in immune defense, and secretes XCL1 chemokines, facilitating interactions with maternal dendritic cells and fetal extravillous trophoblasts (Vento-Tormo et al., 2018). http://purl.obolibrary.org/obo/GO_0140075 regulation of lipoprotein transport http://purl.obolibrary.org/obo/GO_0051223 regulation of protein transport Any process that controls lipoprotein transport. http://purl.obolibrary.org/obo/CL_4052053 uterine natural killer cell 3, human http://purl.obolibrary.org/obo/CL_4052028 uterine natural killer cell A uterine natural killer subset found in the endometrial lining during the non-pregnant state (Garcia-Alonso et al., 2021) and in the decidua during pregnancy (Vento-Tormo et al., 2018), becoming the dominant uNK subset late in pregnancy. It expresses the uterine resident marker CD49a and is distinguished from uNK1 and uNK2 by CD160 (Marečková et al., 2024) and CD103 expression, the absence of CD39, and low KIR levels (Whettlock et al., 2022). Resembling intraepithelial ILC1 cells, uNK3 primarily supports uterine immune defense (Huhn et al., 2020) and indirectly influences trophoblast behavior through chemokine secretion, such as CCL5 (Vento-Tormo et al., 2018). http://purl.obolibrary.org/obo/GO_0140076 negative regulation of lipoprotein transport http://purl.obolibrary.org/obo/GO_0051224 negative regulation of protein transport Any process that stops, prevents or reduces the frequency, rate or extent of lipoprotein transport. http://purl.obolibrary.org/obo/CL_4052055 mature NK T cell, human http://purl.obolibrary.org/obo/CL_0000814 mature NK T cell A mature NK T cell that can be identified by the expression of CD56 in humans. http://purl.obolibrary.org/obo/GO_0140077 positive regulation of lipoprotein transport http://purl.obolibrary.org/obo/GO_0051222 positive regulation of protein transport Any process that activates or increases the rate or extent of lipoprotein transport. http://purl.obolibrary.org/obo/CL_4070010 gastric mill neuron http://purl.obolibrary.org/obo/CL_0000100 motor neuron A motor neuron that moves the medial tooth forward http://purl.obolibrary.org/obo/UBERON_0036244 secretion of serous membrane http://purl.obolibrary.org/obo/UBERON_0007779 transudate A transudate found in the serous sac. http://purl.obolibrary.org/obo/CL_4070011 lateral gastric neuron http://purl.obolibrary.org/obo/CL_0000100 motor neuron A motor neuron that closes the lateral teeth. http://purl.obolibrary.org/obo/GO_0061951 establishment of protein localization to plasma membrane http://purl.obolibrary.org/obo/GO_0090150 establishment of protein localization to membrane The directed movement of a protein to a specific location in a plasma membrane. http://purl.obolibrary.org/obo/CL_4070012 inferior cardiac neuron http://purl.obolibrary.org/obo/CL_0000100 motor neuron A motor neuron that controls ventral stomach grooves leading to pyloric filter. http://purl.obolibrary.org/obo/UBERON_0036289 anterior wall of right ventricle http://purl.obolibrary.org/obo/UBERON_0036286 wall of right ventricle Region of wall of right ventricle which is continuous with the lateral and septal walls of right ventricle. http://purl.obolibrary.org/obo/CL_4070013 ventricular dilator motor neuron http://purl.obolibrary.org/obo/CL_0000100 motor neuron A motor neuron that controls ventral stomach grooves leading to pyloric filter. http://purl.obolibrary.org/obo/CL_4070014 pyloric motor neuron http://purl.obolibrary.org/obo/CL_0000100 motor neuron A motor neuron that controls pyloric filter movements; innervates the pyloric muscle. http://purl.obolibrary.org/obo/PR_000044633 dopamine receptor http://purl.obolibrary.org/obo/PR_000001094 rhodopsin-like G-protein coupled receptor A rhodopsin-like G-protein coupled receptor that is a translation product of the human DRD1 to DRD5 genes, 1:1 orthologs thereof, or pro-orthologs thereof. http://purl.obolibrary.org/obo/CL_4070015 pyloric dilator neuron http://purl.obolibrary.org/obo/CL_0000100 motor neuron A motor neuron that controls the cardiopyloric valve. http://purl.obolibrary.org/obo/PR_000044637 calcitonin receptor protein http://purl.obolibrary.org/obo/PR_000001094 rhodopsin-like G-protein coupled receptor A rhodopsin-like G-protein coupled receptor that is a translation product of the human CALCR or CALCRL genes, 1:1 orthologs thereof, or a semi-ortholog thereof. http://purl.obolibrary.org/obo/CL_4070016 anterior burster neuron http://purl.obolibrary.org/obo/CL_0000099 interneuron Pyloric pacemaker neuron that provides feedback to commissural ganglia (CoG) neurons. http://purl.obolibrary.org/obo/PR_000044650 sodium-activated potassium channel protein http://purl.obolibrary.org/obo/PR_000044651 calcium- and sodium-activated potassium channel protein A potassium channel protein that is activated by sodium. A sodium-activated potassium channel enables the transmembrane transfer of potassium by a channel that opens in response to stimulus by a sodium ion or ions. http://purl.obolibrary.org/obo/CL_4070017 lateral pyloric motor neuron http://purl.obolibrary.org/obo/CL_0000100 motor neuron A motor neuron that controls pyloric filter movements; innervates the lateral pyloric muscle. http://purl.obolibrary.org/obo/PR_000044654 voltage-gated potassium channel protein http://purl.obolibrary.org/obo/PR_000044655 potassium channel protein A potassium channel protein that has voltage-gated potassium channel activity. A voltage-gated potassium channel enables the transmembrane transfer of a potassium ion by a voltage-gated channel. A voltage-gated channel enables the transmembrane transfer of a solute by a channel whose open state is dependent on the voltage across the membrane in which it is embedded. http://purl.obolibrary.org/obo/CL_4307133 BAM NN_1 Mrc1 border associated macrophage (Mmus) http://purl.obolibrary.org/obo/CL_4301625 border associated macrophage (Mmus) A border associated macrophage of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Mrc1 (Mmus), Pf4 (Mmus). It is distinguished from other BAM NN cells by expression of Mrc1, Pf4. These cells are located in the Medulla, Cerebellum, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5313 BAM NN_1. http://purl.obolibrary.org/obo/PR_000044658 voltage-gated calcium channel protein http://purl.obolibrary.org/obo/PR_000044628 voltage-gated ion channel protein A voltage-gated ion channel protein that has voltage-gated calcium channel activity. A voltage-gated calcium channel enables the transmembrane transfer of a calcium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. http://purl.obolibrary.org/obo/CL_4047060 BAG3-positive monocyte http://purl.obolibrary.org/obo/CL_0000576 monocyte A circulating mononuclear phagocyte characterized by the expression of BCL-2-associated athanogene 3 (BAG3) protein, a co-chaperone involved in protein quality control and anti-apoptotic processes. (Fontanella, 2009). It undergoes cellular stress during the differentiation into M2 macrophages and is linked to poor survival rates in multiple cancer types. (Park, 2023) http://purl.obolibrary.org/obo/PR_000044660 voltage-gated sodium channel protein http://purl.obolibrary.org/obo/PR_000044628 voltage-gated ion channel protein A voltage-gated ion channel protein that has voltage-gated sodium channel activity. A voltage-gated sodium channel enables the transmembrane transfer of a sodium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. http://purl.obolibrary.org/obo/CL_4301590 Astro-NT NN_2 astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4300358 subcortical astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gja1 (Mmus), A330076C08Rik (Mmus), Itih3 (Mmus), Gria2 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1160 Astro-NT NN_2. http://purl.obolibrary.org/obo/PR_000044668 nicotinic acetylcholine receptor protein http://purl.obolibrary.org/obo/PR_000044671 ligand-gated ion channel protein A ligand-gated ion channel protein that is a translation product of the human CHRNA1-7, CHRNA9-10, CHRNB1-4, CHRNG, CHRND, or CHRNE genes, 1:1 orthologs thereof, or a semi-ortholog thereof. http://purl.obolibrary.org/obo/CL_4052060 spinous cell http://purl.obolibrary.org/obo/CL_0000312 keratinocyte A differentiating keratinocyte found in the epidermis and oral epithelium, located in the stratum spinosum, characterized by a spiny appearance due to abundant intercellular desmosomal junctions. http://purl.obolibrary.org/obo/PR_000049983 ion channel protein http://purl.obolibrary.org/obo/PR_000044676 channel protein A channel protein that has ion channel activity. An ion channel enables the facilitated diffusion of an ion (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. http://purl.obolibrary.org/obo/CL_4307049 Astro-TE NN_5 Hs3st3a1 astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301595 Astro-TE NN_5 astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of S1pr1 (Mmus), Thbs4 (Mmus), Hs3st3a1 (Mmus), Sfrp1 (Mmus). It is distinguished from other Astro-TE NN_5 cells by expression of Hs3st3a1, Sfrp1. These cells are located in the Olfactory areas, brain , in or close to the regions: Anterior olfactory nucleus, corpus callosum, body, lateral ventricle, corpus callosum, anterior forceps . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5229 Astro-TE NN_5. http://purl.obolibrary.org/obo/CL_4072009 A12 dopaminergic neuron http://purl.obolibrary.org/obo/CL_0012001 neuron of the forebrain A type of dopaminergic neuron found in the arcuate hypothalamic nucleus, involved in neuroendocrine regulation, metabolic homeostasis and prolactin secretion. http://purl.obolibrary.org/obo/PR_000044671 ligand-gated ion channel protein http://purl.obolibrary.org/obo/PR_000049983 ion channel protein An ion channel protein that has ligand-gated ion channel activity. The ligand-gated ion channel opens when a specific ligand has been bound by the channel complex or one of its constituent parts. http://purl.obolibrary.org/obo/CL_4307114 ABC NN_1 Dapl1 arachnoid barrier cell (Mmus) http://purl.obolibrary.org/obo/CL_4301616 arachnoid barrier cell (Mmus) A arachnoid barrier cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Slc47a1 (Mmus), Dapl1 (Mmus). It is distinguished from other ABC NN cells by expression of Dapl1. These cells are located in the brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5294 ABC NN_1. http://purl.obolibrary.org/obo/PR_000044628 voltage-gated ion channel protein http://purl.obolibrary.org/obo/PR_000049983 ion channel protein An ion channel protein that has voltage-gated ion channel activity. A voltage-gated ion channel enables the transmembrane transfer of a solute by a channel whose open state is dependent on the voltage across the membrane in which it is embedded. http://purl.obolibrary.org/obo/CL_4033105 superior cervical ganglion SST neuron http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron A sympathetic neuron that has the soma located in the superior cervical ganglion and expresses the marker somatostatin (SST). http://purl.obolibrary.org/obo/PR_000044651 calcium- and sodium-activated potassium channel protein http://purl.obolibrary.org/obo/PR_000044655 potassium channel protein A potassium channel protein that is activated either by calcium or by sodium. http://purl.obolibrary.org/obo/CL_4307037 Astro-NT NN_2 Gm30524 astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301590 Astro-NT NN_2 astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Aqp4 (Mmus), A330076C08Rik (Mmus), Fbln5 (Mmus), Mdga2 (Mmus). It is distinguished from other Astro-NT NN_2 cells by expression of Gm30524. These cells are located in the Medulla, Cerebellum, brain , in or close to the regions: Ventral cochlear nucleus, arbor vitae . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5217 Astro-NT NN_2. http://purl.obolibrary.org/obo/PR_000044655 potassium channel protein http://purl.obolibrary.org/obo/PR_000044628 voltage-gated ion channel protein A voltage-gated ion channel protein that has potassium channel activity. A potassium channel enables the facilitated diffusion of a potassium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. http://purl.obolibrary.org/obo/CL_4033152 jugular ganglion TRPV1 neuron http://purl.obolibrary.org/obo/CL_0000101 sensory neuron A sensory neuron that has the soma located in the jugular ganglion and expresses the marker transient receptor potential vanilloid 1 (TRPV1). http://purl.obolibrary.org/obo/PR_000044676 channel protein http://purl.obolibrary.org/obo/PR_000000001 protein A protein that has channel activity. Channel proteins enable energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel. http://purl.obolibrary.org/obo/CL_4301585 CB Granule Glut_2 cerebellar granule cell (Mmus) http://purl.obolibrary.org/obo/CL_4300354 cerebellar granule cell (Mmus) A cerebellar granule cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gabra6 (Mmus), Gap43 (Mmus), Rab37 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1155 CB Granule Glut_2. http://purl.obolibrary.org/obo/PR_P08575-3 receptor-type tyrosine-protein phosphatase C isoform CD45RABC (human) http://purl.obolibrary.org/obo/PR_000001014 receptor-type tyrosine-protein phosphatase C isoform CD45RABC A receptor-type tyrosine-protein phosphatase C isoform CD45RABC that is encoded in the genome of human. http://purl.obolibrary.org/obo/CL_4307110 OEC NN_1 Gdpd4 olfactory ensheathing cell (Mmus) http://purl.obolibrary.org/obo/CL_4301615 olfactory ensheathing cell (Mmus) A olfactory ensheathing cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Apod (Mmus), Aqp1 (Mmus), Cldn5 (Mmus). It is distinguished from other OEC cells by expression of Gdpd4, Cldn5. These cells are located in the brain , in or close to the regions: olfactory nerve layer of main olfactory bulb . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5290 OEC NN_1. http://purl.obolibrary.org/obo/PR_P08575-4 receptor-type tyrosine-protein phosphatase C isoform CD45RO (human) http://purl.obolibrary.org/obo/PR_000001017 receptor-type tyrosine-protein phosphatase C isoform CD45RO A receptor-type tyrosine-protein phosphatase C isoform CD45RO that is encoded in the genome of human. http://purl.obolibrary.org/obo/CL_4301603 Tanycyte NN_2 tanycyte (Mmus) http://purl.obolibrary.org/obo/CL_4300362 tanycyte (Mmus) A tanycyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gpr50 (Mmus), Ccdc170 (Mmus), Nkx2-4 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1173 Tanycyte NN_2. http://purl.obolibrary.org/obo/PR_P08575-8 receptor-type tyrosine-protein phosphatase C isoform CD45RA (human) http://purl.obolibrary.org/obo/PR_000001015 receptor-type tyrosine-protein phosphatase C isoform CD45RA A receptor-type tyrosine-protein phosphatase C isoform CD45RA that is encoded in the genome of human. http://purl.obolibrary.org/obo/CL_4301598 Astro-OLF NN_3 astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4300360 olfactory areas astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Ednrb (Mmus), Hs3st3a1 (Mmus), C230072F16Rik (Mmus), Gria2 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1168 Astro-OLF NN_3. http://purl.obolibrary.org/obo/GO_0120178 steroid hormone biosynthetic process http://purl.obolibrary.org/obo/GO_0006694 steroid biosynthetic process The chemical reactions and pathways resulting in the formation of any steroid hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone. http://purl.obolibrary.org/obo/GO_0062125 regulation of mitochondrial gene expression http://purl.obolibrary.org/obo/GO_0010468 regulation of gene expression Any process that modulates the frequency, rate or extent of mitochondrial gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA). http://purl.obolibrary.org/obo/CL_4306992 DCO Il22 Gly-Gaba_2 cerebellar neuron (Mmus) http://purl.obolibrary.org/obo/CL_4300348 DCO Il22 Gly-Gaba cerebellar neuron (Mmus) A cerebellar neuron of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Il22 (Mmus), Edaradd (Mmus). It is distinguished from other DCO Il22 Gly-Gaba cells by expression of Ppp1r17. It is GABAergic and glycinergic (inferred from expression of Slc32a1, Hdc, Slc6a5, Gad2, Gad1). These cells are located in the Medulla, Cerebellum, brain , in or close to the regions: Paraflocculus, arbor vitae, Dorsal cochlear nucleus . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5172 DCO Il22 Gly-Gaba_2. http://purl.obolibrary.org/obo/GO_0150119 negative regulation of protein localization to cell-cell junction http://purl.obolibrary.org/obo/GO_0150106 regulation of protein localization to cell-cell junction Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell-cell junction. http://purl.obolibrary.org/obo/CL_4072005 A8 dopaminergic neuron http://purl.obolibrary.org/obo/CL_2000097 midbrain dopaminergic neuron A type of midbrain dopaminergic neuron localized in the retrorubral field which projects to limbic and cortical regions involved in emotion, motivation, and reward. http://purl.obolibrary.org/obo/GO_0150146 cell junction disassembly http://purl.obolibrary.org/obo/GO_0034330 cell junction organization The disaggregation of a cell junction into its constituent components. http://purl.obolibrary.org/obo/GO_0160276 negative regulation of beige fat cell differentiation http://purl.obolibrary.org/obo/GO_0045599 negative regulation of fat cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of beige fat cell differentiation. http://purl.obolibrary.org/obo/GO_0120229 protein localization to motile cilium http://purl.obolibrary.org/obo/GO_0061512 protein localization to cilium A process in which a protein is transported to, or maintained in, a location within a motile cilium. http://purl.obolibrary.org/obo/CL_4301625 border associated macrophage (Mmus) http://purl.obolibrary.org/obo/CL_4042003 border associated macrophage A border associated macrophage of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Mrc1 (Mmus), Maf (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1195 BAM NN_1. http://purl.obolibrary.org/obo/GO_0120254 olefinic compound metabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process The chemical reactions and pathways involving an olefinic compound, any compound which contains a carbon-carbon double bond (aka C=C). http://purl.obolibrary.org/obo/UBERON_0016514 cavity of left ventricle http://purl.obolibrary.org/obo/UBERON_0035763 cavity of cardiac chamber Luminal space of the left ventricle of the heart. http://purl.obolibrary.org/obo/GO_0120255 olefinic compound biosynthetic process http://purl.obolibrary.org/obo/GO_0009058 biosynthetic process The chemical reactions and pathways resulting in the formation of an olefinic compound, any compound which contains a carbon-carbon double bond (aka C=C). http://purl.obolibrary.org/obo/CL_0002323 amniocyte http://purl.obolibrary.org/obo/CL_0000349 extraembryonic cell A cell of a fetus which is suspended in the amniotic fluid. Amniocytes are considered to arise from several tissues including fetal skin, the fetal urinary tract, umbilical cord, and the inner amniotic surface. http://purl.obolibrary.org/obo/GO_0120256 olefinic compound catabolic process http://purl.obolibrary.org/obo/GO_0009056 catabolic process The chemical reactions and pathways resulting in the breakdown of an olefinic compound, any compound which contains a carbon-carbon double bond (aka C=C). http://purl.obolibrary.org/obo/UBERON_0005872 1st arch pharyngeal cleft http://purl.obolibrary.org/obo/UBERON_0005879 pharyngeal cleft A groove that is situated between the 1st and 2nd pharyngeal arch. http://purl.obolibrary.org/obo/CL_0008046 extrafusal muscle fiber http://purl.obolibrary.org/obo/CL_0008002 skeletal muscle fiber A skeletal muscle fiber that is innervated by alpha motor neuron and generates tension by contracting, thereby allowing for skeletal movement. These fibers make up the large mass of skeletal muscle tissue and are attached to bones by tendons. http://purl.obolibrary.org/obo/UBERON_0016511 lamina propria of fundus of stomach http://purl.obolibrary.org/obo/UBERON_8600138 stomach lamina propria A lamina propria that is part of a mucosa of fundus of stomach. http://purl.obolibrary.org/obo/CL_0008047 intrafusal muscle fiber http://purl.obolibrary.org/obo/CL_0008002 skeletal muscle fiber A skeletal muscle fiber that is part of a muscle spindle. These are specialized muscle fibers that serve as proprioceptors, detecting the amount and rate of change in length of a muscle. They are innervated by both sensory neurons and motor neurons (gamma and beta motorneurons, collectively referred to as fusimotor neurons). http://purl.obolibrary.org/obo/UBERON_0007831 pectoral girdle skeleton http://purl.obolibrary.org/obo/UBERON_0010719 girdle skeleton A subdivision of a limb or fin skeleton consisting of bones which connects the upper limb or fin to the axial skeleton on each side. It consists of the clavicle and scapula in humans and, in those species with three bones in the pectoral girdle, the coracoid. Some mammalian species (e.g. the dog and the horse) have only the scapula. In humans, the only joints between the shoulder girdle and axial skeleton are the sternoclavicular joints on each side. No joint exists between each scapula and the rib cage; instead the muscular connection between the two permits relatively great mobility of the shoulder girdle in relation to the pelvic girdle. In those species having only the scapula, no joint exists between the forelimb and the thorax, the only attachment being muscular[WP]. Examples: There are only two instances, right and left pectoral girdle skeletons. http://purl.obolibrary.org/obo/CL_0019031 intestine goblet cell http://purl.obolibrary.org/obo/CL_0002563 intestinal epithelial cell Goblet cells reside throughout the length of the small and large intestine and are responsible for the production and maintenance of the protective mucus blanket by synthesizing and secreting high-molecular-weight glycoproteins known as mucins. Human intestinal goblet cells secrete the MUC2 mucin, as well as a number of typical mucus components: CLCA1, FCGBP, AGR2, ZG16, and TFF3. http://purl.obolibrary.org/obo/GO_0120006 regulation of glutamatergic neuron differentiation http://purl.obolibrary.org/obo/GO_0045664 regulation of neuron differentiation Any process that modulates the frequency, rate or extent of glutamatergic neuron differentiation. http://purl.obolibrary.org/obo/CL_0019032 intestinal tuft cell http://purl.obolibrary.org/obo/CL_0002563 intestinal epithelial cell A tuft cell that is part of the intestinal epithelium, characterized by a distinctive apical tuft and lateral cytospinules connecting to neighbouring cells. This cell senses luminal stimuli via taste receptors and succinate signalling, initiating type 2 immune responses through the secretion of interleukin-25 while modulating epithelial regeneration through prostaglandin synthesis. It expresses key molecular markers such as doublecortin-like kinase 1 (DCLK1) in mice (Hendel et al., 2022), and KIT proto-oncogene in humans (Huang et al., 2024). Developed from intestinal crypt stem cells, this cell requires transcription factor POU2F3 for its development. http://purl.obolibrary.org/obo/GO_0120007 negative regulation of glutamatergic neuron differentiation http://purl.obolibrary.org/obo/GO_0045665 negative regulation of neuron differentiation Any process that stops, prevents or reduces the frequency, rate or extent of glutamatergic neuron differentiation. http://purl.obolibrary.org/obo/UBERON_8410007 myenteric nerve plexus of anorectum http://purl.obolibrary.org/obo/UBERON_0002439 myenteric nerve plexus Myenteric nerve plexus that is located in the anorectum. http://purl.obolibrary.org/obo/GO_0120008 positive regulation of glutamatergic neuron differentiation http://purl.obolibrary.org/obo/GO_0045666 positive regulation of neuron differentiation Any process that activates or increases the frequency, rate or extent of glutamatergic neuron differentiation. http://purl.obolibrary.org/obo/UBERON_8410058 myenteric nerve plexus of colon http://purl.obolibrary.org/obo/UBERON_0002439 myenteric nerve plexus Myenteric nerve plexus that is located in the colon. http://purl.obolibrary.org/obo/GO_1905962 glutamatergic neuron differentiation http://purl.obolibrary.org/obo/GO_0030182 neuron differentiation The process in which a relatively unspecialized cell acquires the specialized features of a glutamatergic neuron. http://purl.obolibrary.org/obo/UBERON_8410060 colon smooth muscle circular layer http://purl.obolibrary.org/obo/UBERON_0012398 large intestine smooth muscle circular layer A circular muscle layer of muscular coat that is part of a colon smooth muscle. http://purl.obolibrary.org/obo/GO_0110077 vesicle-mediated intercellular transport http://purl.obolibrary.org/obo/GO_0010496 intercellular transport A cellular transport process in which transported substances are moved in extracellular vesicles between cells; transported substances are enclosed in the vesicle lumen or located in the extracellular vesicle membrane. http://purl.obolibrary.org/obo/UBERON_8410061 colon smooth muscle longitudinal layer http://purl.obolibrary.org/obo/UBERON_0012399 large intestine smooth muscle longitudinal layer A longitudinal muscle layer of muscular coat that is part of a colon smooth muscle. http://purl.obolibrary.org/obo/GO_0110079 regulation of placenta blood vessel development http://purl.obolibrary.org/obo/GO_1901342 regulation of vasculature development Any process that modulates the frequency, rate or extent of placenta blood vessel development. http://purl.obolibrary.org/obo/UBERON_8410063 myenteric nerve plexus of small intestine http://purl.obolibrary.org/obo/UBERON_0002439 myenteric nerve plexus Myenteric nerve plexus that is part of the small intestine. http://purl.obolibrary.org/obo/GO_0110080 positive regulation of placenta blood vessel development http://purl.obolibrary.org/obo/GO_0051094 positive regulation of developmental process Any process that activates or increases the frequency, rate or extent of placenta blood vessel development. http://purl.obolibrary.org/obo/CL_4028002 alveolar capillary type 1 endothelial cell http://purl.obolibrary.org/obo/CL_4028001 pulmonary capillary endothelial cell An alveolar capillary endothelial cell that is located distally to alveolar capillary type 2 endothelial cells. http://purl.obolibrary.org/obo/GO_0110081 negative regulation of placenta blood vessel development http://purl.obolibrary.org/obo/GO_0051093 negative regulation of developmental process Any process that stops, prevents or reduces the frequency, rate or extent of placenta blood vessel development. http://purl.obolibrary.org/obo/CL_0009097 embryonic skeletal muscle fiber http://purl.obolibrary.org/obo/CL_0008002 skeletal muscle fiber A skeletal muscle fiber found in an embryo. In mammalian embryos, skeletal muscle expresses myosin heavy chain-embryonic (MyHC-emb, encoded by the MYH3 gene), which regulates skeletal muscle development. http://purl.obolibrary.org/obo/GO_0140157 ammonium import across plasma membrane http://purl.obolibrary.org/obo/GO_0072488 ammonium transmembrane transport The directed movement of an ammonium ion from outside of a cell, across the plasma membrane and into the cytosol. http://purl.obolibrary.org/obo/CL_4030009 epithelial cell of proximal tubule segment 1 http://purl.obolibrary.org/obo/CL_1000838 kidney proximal convoluted tubule epithelial cell A brush border cell that is part of segment 1 (S1) of the proximal tubule epithelium, located in the renal cortex. http://purl.obolibrary.org/obo/GO_0150031 regulation of protein localization to lysosome http://purl.obolibrary.org/obo/GO_0032880 regulation of protein localization Any process that modulates the frequency, rate or extent of protein localization to lysosome. http://purl.obolibrary.org/obo/CL_4030011 epithelial cell of proximal tubule segment 3 http://purl.obolibrary.org/obo/CL_1000839 kidney proximal straight tubule epithelial cell A brush border cell that is part of segment 3 (S3) of the proximal tubule epithelium, which extends from the medullary rays of the renal cortex into the outer medulla. http://purl.obolibrary.org/obo/GO_0150032 positive regulation of protein localization to lysosome http://purl.obolibrary.org/obo/GO_1903829 positive regulation of protein localization Any process that activates or increases the frequency, rate or extent of protein localization to lysosome. http://purl.obolibrary.org/obo/UBERON_8480000 iliac vein smooth muscle tissue http://purl.obolibrary.org/obo/UBERON_0004696 venous system smooth muscle A portion of smooth muscle tissue that is part of an iliac vein. http://purl.obolibrary.org/obo/GO_0150033 negative regulation of protein localization to lysosome http://purl.obolibrary.org/obo/GO_1903828 negative regulation of protein localization Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to lysosome. http://purl.obolibrary.org/obo/UBERON_8480001 capillary of brain http://purl.obolibrary.org/obo/UBERON_0003499 brain blood vessel A capillary that is part of the brain. http://purl.obolibrary.org/obo/GO_0061983 meiosis II cell cycle process http://purl.obolibrary.org/obo/GO_1903046 meiotic cell cycle process A process that coontributes to the second meiotic division. The second meiotic division separates chromatids resulting in a haploid number of chromosomes. http://purl.obolibrary.org/obo/UBERON_8480002 thoracic aorta smooth muscle tissue http://purl.obolibrary.org/obo/UBERON_0004178 aorta smooth muscle tissue A portion of smooth muscle tissue that is part of the thoracic aorta. http://purl.obolibrary.org/obo/GO_0150077 regulation of neuroinflammatory response http://purl.obolibrary.org/obo/GO_0050727 regulation of inflammatory response Any process that modulates the frequency, rate or extent of neuroinflammatory response. http://purl.obolibrary.org/obo/GO_0120316 sperm flagellum assembly http://purl.obolibrary.org/obo/GO_0044458 motile cilium assembly The assembly and organization of the sperm flagellum, the microtubule-based axoneme and associated structures that are part of a sperm flagellum (or cilium). http://purl.obolibrary.org/obo/UBERON_8480003 iliac artery smooth muscle tissue http://purl.obolibrary.org/obo/UBERON_0002111 artery smooth muscle tissue A portion of smooth muscle tissue that is part of an iliac artery. http://purl.obolibrary.org/obo/CL_0011029 cnidocyte http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell An explosive cell containing one giant secretory organelle called a cnidocyst (also known as a cnida (plural cnidae) or nematocyst) that contains a toxin responsible for the stings delivered by a cnidarian to other organisms. Cnidae are used to capture prey and as a defense against predators. The presence of cnidocytes defines the phylum Cnidaria (corals, sea anemones, hydrae, jellyfish, etc.). http://purl.obolibrary.org/obo/UBERON_8480004 iliac vein endothelium http://purl.obolibrary.org/obo/UBERON_0001919 endothelium of vein An endothelium that is part of an iliac vein. http://purl.obolibrary.org/obo/CL_4023107 reticulospinal neuron http://purl.obolibrary.org/obo/CL_2000029 central nervous system neuron A neuron with soma location in the reticular formation with axons that extend into the spinal cord such. Reticulospinal neuron activity can lead to a variety of motor behaviors. http://purl.obolibrary.org/obo/UBERON_8480005 placental artery endothelium http://purl.obolibrary.org/obo/UBERON_0005292 extraembryonic tissue An endothelium that is part of the placental artery. http://purl.obolibrary.org/obo/CL_0009038 colon macrophage http://purl.obolibrary.org/obo/CL_0000235 macrophage A macrophage that is located in the colon. http://purl.obolibrary.org/obo/UBERON_8480006 mesenteric lymphatic vessel http://purl.obolibrary.org/obo/UBERON_0001473 lymphatic vessel Lymphatic vessel that is part of the mesentery. http://purl.obolibrary.org/obo/CL_0009060 marginal zone B cell of lymph node http://purl.obolibrary.org/obo/CL_0000785 mature B cell A mature B cell located in the marginal zone of the lymph node. http://purl.obolibrary.org/obo/UBERON_8480007 placental artery http://purl.obolibrary.org/obo/UBERON_0022358 placenta blood vessel An artery that is part of the placenta. http://purl.obolibrary.org/obo/PATO_0070060 quality of interaction of a substance with electromagnetic radiation http://purl.obolibrary.org/obo/PATO_0002198 quality of a substance A quality of a substance on which or through which electromagnetic radiation impinges or traverses with respect to radiation. This substance quality changes the quality of the incident radiation with respect to any of: intensity, direction, scatter and wavelength. http://purl.obolibrary.org/obo/UBERON_8480008 placental vein http://purl.obolibrary.org/obo/UBERON_0022358 placenta blood vessel A vein that is part of the placenta. http://purl.obolibrary.org/obo/CL_4030003 interstitial cell of thymus http://purl.obolibrary.org/obo/CL_4030001 stromal cell of thymus A cell that makes up the loose connective tissue of the thymus. http://purl.obolibrary.org/obo/GO_0160043 catecholamine secretion, neurotransmission http://purl.obolibrary.org/obo/GO_0050432 catecholamine secretion The regulated release of catecholamine by a cell in which the catecholamine acts as a neurotransmitter. http://purl.obolibrary.org/obo/CL_0003026 retinal ganglion cell D1 http://purl.obolibrary.org/obo/CL_0003001 bistratified retinal ganglion cell A bistratified retinal ganglion cell that has a small dendrite fields with a sparse dendrite arbor terminating in S2 and S3. http://purl.obolibrary.org/obo/CL_0003012 G9 retinal ganglion cell http://purl.obolibrary.org/obo/CL_0000740 retinal ganglion cell A mono-stratified retinal ganglion cell that has a large dendritic field and a medium dendritic arbor with post synaptic terminals in sublaminar layer S1 and S2. http://purl.obolibrary.org/obo/CL_0003044 M11 retinal ganglion cell http://purl.obolibrary.org/obo/CL_0003001 bistratified retinal ganglion cell A bistratified ganglion cell with small, dense dendritic fields that terminate in S1 and S3. http://purl.obolibrary.org/obo/CL_0004239 wavy bistratified amacrine cell http://purl.obolibrary.org/obo/CL_0004252 medium field retinal amacrine cell A bistratified amacrine cell with a medium dendritic field and post-synaptic terminals in S1-S2, and S4. http://purl.obolibrary.org/obo/CL_0004161 510 nm-cone http://purl.obolibrary.org/obo/CL_0003049 M cone cell A cone whose sensitivity measurements have an average spectral peak of 510 nm. These cones are described in rat. http://purl.obolibrary.org/obo/PATO_0070062 bistratified dendrite cell morphology http://purl.obolibrary.org/obo/PATO_0010006 cell morphology A cell morphology that inheres in neurons with dendrites that stratify at two and only two locations. http://purl.obolibrary.org/obo/CL_4023029 indirect pathway medium spiny neuron http://purl.obolibrary.org/obo/CL_1001474 medium spiny neuron A GABAergic medium spiny neuron located in the striatum that gives rise to the indirect basal ganglia pathway. It projects to the GPe, where its axon typically ramifies in two regions but does not extend beyond this nucleus (Gerfen et al., 2022). It selectively expresses the D2 dopamine receptor (DRD2), which couples to inhibitory G-proteins (Gi/o) to decrease cAMP and suppress PKA-mediated signaling (Gerfen et al., 2022). Morphologically, this cell displays fewer and shorter dendrites than the MSN-D1 and receives fewer glutamatergic inputs, yet it exhibits significantly higher intrinsic excitability (Gertler et al., 2022). Functionally, activation of this cell suppresses competing or alternative motor actions by inhibiting GPe neurons, leading through STN and other GPe circuits to increased GPi/SNr output and stronger inhibition of thalamic and brainstem targets (Mink, 1996; Tecuapetla et al., 2016). http://purl.obolibrary.org/obo/CL_4023062 dentate gyrus neuron http://purl.obolibrary.org/obo/CL_0002608 hippocampal neuron A neuron with its soma located in the dentate gyrus of the hippocampus. http://purl.obolibrary.org/obo/CL_4033014 peg cell http://purl.obolibrary.org/obo/CL_4052019 fallopian tube non-ciliated epithelial cell A small, narrow, peg-shaped epithelial cell with little cytoplasm that is part of oviduct epithelium. This cell is rarer than the ciliated and secretory epithelial cells of the fallopian tube epithelium and is often found intercalated between them. Peg cells are generally distributed basally along the epithelium and have been found in high concentrations at the fimbriated, distal end of the fallopian tube in humans. It may have a regenerative/stem-cell function. In humans, markers include EPCAM, CD44, and ITGA6. http://purl.obolibrary.org/obo/CL_4023059 committed oligodendrocyte precursor http://purl.obolibrary.org/obo/CL_0000123 neuron associated cell (sensu Vertebrata) An oligodendrocyte precursor cell that is committed to differentiate. http://purl.obolibrary.org/obo/UBERON_8600118 myenteric ganglion http://purl.obolibrary.org/obo/UBERON_0001805 autonomic ganglion A ganglion that is part of a myenteric plexus. The myoenteric ganglion serves as a control center for local gut functions, such as motility. http://purl.obolibrary.org/obo/UBERON_8600006 visceral striated muscle tissue http://purl.obolibrary.org/obo/UBERON_8600004 visceral muscle tissue A striated muscle tissue that is associated with soft internal organs (viscera). http://purl.obolibrary.org/obo/UBERON_8600119 myenteric ganglion of small intestine http://purl.obolibrary.org/obo/UBERON_8600118 myenteric ganglion A myenteric ganglion located in the myenteric plexus of the small intestine. http://purl.obolibrary.org/obo/CL_4030038 CD24-positive, CD-133-positive, vimentin-positive proximal tubular cell http://purl.obolibrary.org/obo/CL_0002306 epithelial cell of proximal tubule A CD24-positive, CD-133-positive, vimentin-positive cell found scattered throughout a renal proximal tubule and that may participate in tubular regeneration. Compared to other proximal tubular cell types, this cell contains less cytoplasm, fewer mitochondria and no brush border. http://purl.obolibrary.org/obo/UBERON_8600120 atrial intrinsic cardiac ganglion http://purl.obolibrary.org/obo/UBERON_0014463 cardiac ganglion A ganglion that is part of the atrial region of the heart. The activation of efferent neurons in this ganglion results in the modulation of heart rate, atrio-ventricular node conduction, and inotropism of atria and ventricles. http://purl.obolibrary.org/obo/CL_4033015 retinal astrocyte http://purl.obolibrary.org/obo/CL_0009004 retinal cell A star-shaped glial cell that is part of some retina. This cell links neurons to blood vessels and may provide structural and physiological support to optic nerve head axons. http://purl.obolibrary.org/obo/UBERON_8600121 lumbar ganglion http://purl.obolibrary.org/obo/UBERON_0009758 abdominal ganglion A ganglion that is part of the lumbar portion of the sympathetic trunk. The neurons in a lumbar ganglion are postganglionic sympathetic neurons that synapse with axons from preganglionic sympathetic neurons. http://purl.obolibrary.org/obo/CL_4033027 diffuse bipolar 1 cell http://purl.obolibrary.org/obo/CL_0000750 OFF-bipolar cell An OFF diffuse bipolar cell that makes synaptic contact with both L/M and S-cone photoreceptors and only minimal contact with rod photoreceptors. http://purl.obolibrary.org/obo/UBERON_8600122 sacral ganglion http://purl.obolibrary.org/obo/UBERON_0009758 abdominal ganglion A ganglion that is part of the sacral portion of the sympathetic trunk. A sacral ganglion consists of postganglionic sympathetic neurons that receive presynaptic input from preganglionic sympathetic axons descending through the sympathetic trunk from thoracolumbar levels. http://purl.obolibrary.org/obo/CL_4033028 diffuse bipolar 2 cell http://purl.obolibrary.org/obo/CL_0000750 OFF-bipolar cell An OFF diffuse bipolar cell that predominantly connects to ON parasol cells and lateral amacrine cells. This cell contains a large number of synaptic ribbons and a small axon arbor area. http://purl.obolibrary.org/obo/UBERON_8600123 lower airway ganglion http://purl.obolibrary.org/obo/UBERON_0001808 parasympathetic ganglion A parasympathetic ganglion that is located within the airway walls of the lower respiratory tract. This ganglion is responsible for controlling the constriction of the airway by stimulating smooth muscle contraction in the lower respiratory tract to regulate airflow. http://purl.obolibrary.org/obo/CL_4033029 diffuse bipolar 3a cell http://purl.obolibrary.org/obo/CL_0000750 OFF-bipolar cell An OFF calbindin-positive bipolar cell that has a large dendritic field and stratifies narrowly close to the middle of the inner plexiform layer. Its axon terminal is characterized by regularly branching and varicose processes resembling beads on a string. Most of DB3a contacts with cones are triad-associated. http://purl.obolibrary.org/obo/UBERON_8600124 fallopian tube epithelium http://purl.obolibrary.org/obo/UBERON_0012274 columnar epithelium A simple columnar epithelium that is part of the fallopian tube. http://purl.obolibrary.org/obo/CL_4033030 diffuse bipolar 3b cell http://purl.obolibrary.org/obo/CL_0000750 OFF-bipolar cell An OFF calbindin-negative bipolar cell that has a large dendritic field and stratifies narrowly close to the middle of the inner plexiform layer. Its axon terminal is characterized by regularly branching and varicose processes resembling beads on a string. Most of DB3b contacts with cones are non-triad-associated. http://purl.obolibrary.org/obo/CL_4307032 Astro-NT NN_1 Kcnk10 astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301589 Astro-NT NN_1 astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Agt (Mmus), Prss35 (Mmus), C4b (Mmus). It is distinguished from other Astro-NT NN_1 cells by expression of Kcnk10, C4b. These cells are located in the Medulla, Cerebellum, brain , in or close to the regions: arbor vitae . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5212 Astro-NT NN_1. http://purl.obolibrary.org/obo/CL_4033031 diffuse bipolar 4 cell http://purl.obolibrary.org/obo/CL_0000749 ON-bipolar cell An ON diffuse bipolar cell that predominantly connects to ON parasol cells and lateral amacrine cells. http://purl.obolibrary.org/obo/PR_000014841 sonic hedgehog protein http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human SHH gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/CL_4033032 diffuse bipolar 6 cell http://purl.obolibrary.org/obo/CL_0000749 ON-bipolar cell An ON diffuse bipolar cell that has a large dendritic field and large axon terminals, which show little or no overlap. This cell predominantly connects to narrow thorny ganglion cells. http://purl.obolibrary.org/obo/PR_000014898 homeobox protein SIX3 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human SIX3 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/CL_4033033 flat midget bipolar cell http://purl.obolibrary.org/obo/CL_0000750 OFF-bipolar cell An OFF bipolar cell with a small dendritic tree that provides most of the triad-associated basal (flat) contacts at cone pedicles. http://purl.obolibrary.org/obo/PR_000014962 vesicular glutamate transporter 2 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human SLC17A6 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/CL_4033034 invaginating midget bipolar cell http://purl.obolibrary.org/obo/CL_0000749 ON-bipolar cell An ON bipolar cell with a small dendritic tree that forms most of the central (invaginating) elements opposite the synaptic ribbon at the cone triad. http://purl.obolibrary.org/obo/PR_000014968 vesicular acetylcholine transporter http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human SLC18A3 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/CL_4033035 giant bipolar cell http://purl.obolibrary.org/obo/CL_0000749 ON-bipolar cell An ON bipolar cell that has large dendritic and axonal fields. http://purl.obolibrary.org/obo/CL_4033036 OFFx cell http://purl.obolibrary.org/obo/CL_0000750 OFF-bipolar cell An OFF bipolar cell that is fovea-specific and expresses FEZF1, NXPH1 and NXPH2. http://purl.obolibrary.org/obo/PR_000015325 gamma-synuclein http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human SNCG gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/CL_4040000 glial restricted tripotential precursor cell http://purl.obolibrary.org/obo/CL_0011115 precursor cell A glial precursor cell that generates oligodendrocytes and type-1 and type-2 astrocytes. It has been shown in some mammals that this cell type may express A2B5, nestin, FGFR-1, FGFR-2, FGFR-3, PLP, and DM-20 antigens. Unlike oligodendrocyte precursor cell, it does not initially express PDGFR-alpha and can differentiate into both type-1 and type-2 astrocytes. http://purl.obolibrary.org/obo/PR_000015426 transcription factor SOX-2 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human SOX2 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/CL_4040001 chorionic girdle cell http://purl.obolibrary.org/obo/CL_0011101 chorionic trophoblast cell A horse-specific, highly invasive trophoblast cell that invades the endometrium where it forms endometrial cups. http://purl.obolibrary.org/obo/PR_000015476 SPARC-like protein 1 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human SPARCL1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/CL_4040002 enteroglial cell http://purl.obolibrary.org/obo/CL_0000125 glial cell Glial cell that provides support to the enteric nervous system. It is involved in enteric neurotransmission, in maintaining the integrity of the mucosal barrier of the gut and serves as a link between the nervous and immune systems of the gut. In enteric nerve strands, glial processes ensheath multiaxonal bundles which distinguishes enteric glia from all other peripheral glia. Ultrastructurally, the most conspicuous trait of an enteroglial cell is the presence of 10 nm filaments, which criss-cross the cell body, form axial bundles in the processes and appear to firmly anchor the cells to the ganglionic surfaces. Similar to astrocytes, their main constituent is glial fibrillary acidic protein (GFAP). http://purl.obolibrary.org/obo/PR_000015557 spondin-1 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human SPON1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_8910001 stomatogastric ganglion http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision The stomatogastric ganglion (STG) consists of about 30 neurons that form two central pattern generator circuits in crustaceans. STG neurons have large soma (~50-100 um) and have complex branches. The STG contains the motor neurons that innervate the striated muscles that move the gastric mill and pyloric regions of the stomach. http://purl.obolibrary.org/obo/PR_000015658 SCO-spondin http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human SSPO gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0018143 transverse process of cervical vertebra http://purl.obolibrary.org/obo/UBERON_0001077 transverse process of vertebra A transverse process that is part of a cervical vertebra. http://purl.obolibrary.org/obo/PR_000015665 somatostatin http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human SST gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0003071 eye primordium http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure Portion of tissue that is part of the anterior neural keel and will form the optic vesicle[ZFA]. A paired ectodermal placode that becomes invaginated to form the embryonic lens vesicles. http://purl.obolibrary.org/obo/PR_000016003 protachykinin-1 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human TAC1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/CL_0002583 subcutaneous preadipocyte http://purl.obolibrary.org/obo/CL_0002334 preadipocyte A preadipocyte that is part of subcutaneous tissue. http://purl.obolibrary.org/obo/PR_000016004 tachykinin-3 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human TAC3 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000016043 T-cell acute lymphocytic leukemia protein 1 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human TAL1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/GO_0099156 cell-cell signaling via exosome http://purl.obolibrary.org/obo/GO_0007267 cell-cell signaling Cell-cell signaling in which the ligand is carried between cells by an exosome. http://purl.obolibrary.org/obo/PR_000016301 tyrosine 3-monooxygenase http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human TH gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/GO_0099157 trans-synaptic signaling via exosome http://purl.obolibrary.org/obo/GO_0099537 trans-synaptic signaling Transynaptic signaling in which the ligand is carried across the synapse by an exosome. http://purl.obolibrary.org/obo/PR_000016401 transmembrane emp24 domain-containing protein 1 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human TMED1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/GO_0099177 regulation of trans-synaptic signaling http://purl.obolibrary.org/obo/GO_0023051 regulation of signaling Any process that modulates the frequency, rate or extent of trans-synaptic signaling. http://purl.obolibrary.org/obo/PR_000016407 tomoregulin-2 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human TMEFF2 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/GO_0099163 synaptic signaling by nitric oxide http://purl.obolibrary.org/obo/GO_0099536 synaptic signaling Cell-cell signaling to or from a synapse, mediated by nitric oxide. http://purl.obolibrary.org/obo/PR_000016626 triggering receptor expressed on myeloid cells 2 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human TREM2 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/GO_0099173 postsynapse organization http://purl.obolibrary.org/obo/GO_0016043 cellular component organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a postsynapse. http://purl.obolibrary.org/obo/PR_000017298 vimentin http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human VIM gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/GO_0099174 regulation of presynapse organization http://purl.obolibrary.org/obo/GO_0050807 regulation of synapse organization Any process that modulates the physical form of a presynapse. http://purl.obolibrary.org/obo/PR_000017299 VIP peptides http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human VIP gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/GO_0140141 mitochondrial potassium ion transmembrane transport http://purl.obolibrary.org/obo/GO_0071805 potassium ion transmembrane transport The process in which a potassium ion is transported across a mitochondrial membrane, into or out of the mitochondrion. http://purl.obolibrary.org/obo/PR_000018311 integrin alpha-E proteolytic cleavage product http://purl.obolibrary.org/obo/PR_000018264 proteolytic cleavage product An integrin alpha-E that has been processed by proteolytic cleavage. http://purl.obolibrary.org/obo/GO_0099185 postsynaptic intermediate filament cytoskeleton organization http://purl.obolibrary.org/obo/GO_0045104 intermediate filament cytoskeleton organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprised of intermediate filament and their associated proteins in the postsynaptic cytoskeleton. http://purl.obolibrary.org/obo/PR_000018335 T-cell surface glycoprotein CD8 alpha chain, signal peptide removed form http://purl.obolibrary.org/obo/PR_000001084 T-cell surface glycoprotein CD8 alpha chain A T-cell surface glycoprotein CD8 alpha chain that has had the signal peptide removed. http://purl.obolibrary.org/obo/GO_0099187 presynaptic cytoskeleton organization http://purl.obolibrary.org/obo/GO_0007010 cytoskeleton organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures and their associated proteins in the presynaptic cytoskeleton. http://purl.obolibrary.org/obo/PR_000018337 T-cell surface glycoprotein CD8 beta chain, signal peptide removed form http://purl.obolibrary.org/obo/PR_000001085 T-cell surface glycoprotein CD8 beta chain A T-cell surface glycoprotein CD8 beta chain that has had the signal peptide removed. http://purl.obolibrary.org/obo/GO_0099188 postsynaptic cytoskeleton organization http://purl.obolibrary.org/obo/GO_0007010 cytoskeleton organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising cytoskeletal filaments and their associated proteins in the postsynaptic cytoskeleton. http://purl.obolibrary.org/obo/PR_000018381 CD48 molecule proteolytic cleavage product http://purl.obolibrary.org/obo/PR_000018264 proteolytic cleavage product A CD48 molecule that has been processed by proteolytic cleavage. http://purl.obolibrary.org/obo/GO_0140146 calcium ion import into vacuole http://purl.obolibrary.org/obo/GO_0034486 vacuolar transmembrane transport The directed movement of calcium cations into the vacuole across the vacuolar membrane. http://purl.obolibrary.org/obo/PR_000018390 L-selectin proteolytic cleavage product http://purl.obolibrary.org/obo/PR_000018264 proteolytic cleavage product An L-selectin that has been processed by proteolytic cleavage. http://purl.obolibrary.org/obo/GO_0140253 cell-cell fusion http://purl.obolibrary.org/obo/GO_0009987 cellular process A cellular process in which two or more cells combine together, their plasma membrane fusing, producing a single cell. In some cases, nuclei fuse, producing a polyploid cell, while in other cases, nuclei remain separate, producing a syncytium. http://purl.obolibrary.org/obo/PR_000018406 cell adhesion molecule CEACAM8 proteolytic cleavage product http://purl.obolibrary.org/obo/PR_000018264 proteolytic cleavage product A cell adhesion molecule CEACAM8 that has been processed by proteolytic cleavage. http://purl.obolibrary.org/obo/PR_000044669 P2X receptor protein http://purl.obolibrary.org/obo/PR_000044671 ligand-gated ion channel protein A ligand-gated ion channel protein that is a translation product of the human P2RX1, P2RX2, P2RX3, P2RX4, P2RX5, P2RX6, or P2RX7 genes, 1:1 orthologs thereof, or a semi-ortholog thereof. http://purl.obolibrary.org/obo/PR_000018481 cadherin-1 proteolytic cleavage product http://purl.obolibrary.org/obo/PR_000018264 proteolytic cleavage product A cadherin-1 that has been processed by proteolytic cleavage. http://purl.obolibrary.org/obo/CL_4023056 vascular leptomeningeal cell (Mmus) http://purl.obolibrary.org/obo/CL_4023051 vascular leptomeningeal cell A type of mouse mesothelial fibroblast that is derived from the neural crest, is localized on blood vessels, and is a key component of the pia and arachnoid membranes surrounding the brain. http://purl.obolibrary.org/obo/PR_000018546 Thy-1 membrane glycoprotein proteolytic cleavage product http://purl.obolibrary.org/obo/PR_000018264 proteolytic cleavage product A Thy-1 membrane glycoprotein that has been processed by proteolytic cleavage. http://purl.obolibrary.org/obo/CL_0009027 transit amplifying cell of appendix http://purl.obolibrary.org/obo/CL_0002253 epithelial cell of large intestine A transit amplifying cell that is part of a crypt of Lieberkuhn of large intestine. http://purl.obolibrary.org/obo/PR_000018547 cathepsin K proteolytic cleavage product http://purl.obolibrary.org/obo/PR_000018264 proteolytic cleavage product A cathepsin K that has been processed by proteolytic cleavage. http://purl.obolibrary.org/obo/CL_4023052 Betz upper motor neuron http://purl.obolibrary.org/obo/CL_0008049 Betz cell A Betz cell that synapses with lower motor neurons directly. http://purl.obolibrary.org/obo/PR_000018568 low affinity immunoglobulin epsilon Fc receptor proteolytic cleavage product http://purl.obolibrary.org/obo/PR_000018264 proteolytic cleavage product A low affinity immunoglobulin epsilon Fc receptor that has been processed by proteolytic cleavage. http://purl.obolibrary.org/obo/CL_4023093 stellate pyramidal neuron http://purl.obolibrary.org/obo/CL_0000598 pyramidal neuron A pyramidal neuron which lacks a tuft formation but extends small radial distances forming a star-like shape. http://purl.obolibrary.org/obo/PR_000018591 platelet glycoprotein Ib alpha chain proteolytic cleavage product http://purl.obolibrary.org/obo/PR_000018264 proteolytic cleavage product A platelet glycoprotein Ib alpha chain that has been processed by proteolytic cleavage. http://purl.obolibrary.org/obo/CL_0009039 colon goblet cell http://purl.obolibrary.org/obo/CL_1000320 large intestine goblet cell A goblet cell that is located in the colon. http://purl.obolibrary.org/obo/PR_000018594 scavenger receptor cysteine-rich type 1 protein M130 proteolytic cleavage product http://purl.obolibrary.org/obo/PR_000018264 proteolytic cleavage product A scavenger receptor cysteine-rich type 1 protein M130 that has been processed by proteolytic cleavage. http://purl.obolibrary.org/obo/CL_0009046 T cell of medullary sinus of lymph node http://purl.obolibrary.org/obo/CL_0000084 T cell A T cell found in the lymph node medullary sinus. http://purl.obolibrary.org/obo/PR_000018603 transferrin receptor protein 1 proteolytic cleavage product http://purl.obolibrary.org/obo/PR_000018264 proteolytic cleavage product A transferrin receptor protein 1 that has been processed by proteolytic cleavage. http://purl.obolibrary.org/obo/CL_0009047 macrophage of medullary sinus of lymph node http://purl.obolibrary.org/obo/CL_0000235 macrophage A macrophage found in the medullary sinus of the lymph node. http://purl.obolibrary.org/obo/PR_000018606 tumor necrosis factor ligand superfamily member 5 proteolytic cleavage product http://purl.obolibrary.org/obo/PR_000018264 proteolytic cleavage product A tumor necrosis factor ligand superfamily member 5 that has been processed by proteolytic cleavage. http://purl.obolibrary.org/obo/CL_0009048 anorectum macrophage http://purl.obolibrary.org/obo/CL_0000235 macrophage A macrophage that is located in the anorectum. http://purl.obolibrary.org/obo/PR_000018732 C-C motif chemokine 3 proteolytic cleavage product http://purl.obolibrary.org/obo/PR_000018264 proteolytic cleavage product A C-C motif chemokine 3 that has been processed by proteolytic cleavage. http://purl.obolibrary.org/obo/CL_0009050 B cell of anorectum http://purl.obolibrary.org/obo/CL_0000236 B cell A B cell that is located in the anorectum. http://purl.obolibrary.org/obo/PR_000018809 collagen alpha-1(III) chain proteolytic cleavage product http://purl.obolibrary.org/obo/PR_000018264 proteolytic cleavage product A collagen alpha-1(III) chain that has been processed by proteolytic cleavage. http://purl.obolibrary.org/obo/CL_0009051 T cell of anorectum http://purl.obolibrary.org/obo/CL_0000084 T cell A T cell that is located in the anorectum. http://purl.obolibrary.org/obo/PR_000018820 granzyme K proteolytic cleavage product http://purl.obolibrary.org/obo/PR_000018264 proteolytic cleavage product A granzyme K that has been processed by proteolytic cleavage. http://purl.obolibrary.org/obo/CL_0009053 stromal cell of anorectum lamina propria http://purl.obolibrary.org/obo/CL_0009021 stromal cell of lamina propria of large intestine A stromal cell found in the lamina propria of the anorectum. http://purl.obolibrary.org/obo/PR_000018835 granzyme H proteolytic cleavage product http://purl.obolibrary.org/obo/PR_000018264 proteolytic cleavage product A granzyme H that has been processed by proteolytic cleavage. http://purl.obolibrary.org/obo/CL_0009056 transit amplifying cell of anorectum http://purl.obolibrary.org/obo/CL_0002253 epithelial cell of large intestine A transit amplifying cell that is located in the anorectum. http://purl.obolibrary.org/obo/PR_000018883 actin, aortic smooth muscle proteolytic cleavage product http://purl.obolibrary.org/obo/PR_000018264 proteolytic cleavage product An actin, aortic smooth muscle that has been processed by proteolytic cleavage. http://purl.obolibrary.org/obo/CL_0009065 tuft cell of anorectum http://purl.obolibrary.org/obo/CL_0002203 tuft cell of large intestine An intestinal tuft cell that is located in the anorectum. http://purl.obolibrary.org/obo/PR_000019255 cholecystokinin proteolytic cleavage product http://purl.obolibrary.org/obo/PR_000018264 proteolytic cleavage product A cholecystokinin that has been processed by proteolytic cleavage. http://purl.obolibrary.org/obo/CL_0009066 stratified squamous epithelial cell of anal canal http://purl.obolibrary.org/obo/CL_0002253 epithelial cell of large intestine A stratified squamous epithelial cell that is part of the anal canal. http://purl.obolibrary.org/obo/PR_000019396 collagen alpha-1(XI) chain proteolytic cleavage product http://purl.obolibrary.org/obo/PR_000018264 proteolytic cleavage product A collagen alpha-1(XI) chain that has been processed by proteolytic cleavage. http://purl.obolibrary.org/obo/UBERON_8410011 myenteric nerve plexus of appendix http://purl.obolibrary.org/obo/UBERON_0002439 myenteric nerve plexus Myenteric nerve plexus that is located in the vermiform appendix. http://purl.obolibrary.org/obo/PR_000019644 dopamine beta-hydroxylase proteolytic cleavage product http://purl.obolibrary.org/obo/PR_000018264 proteolytic cleavage product A dopamine beta-hydroxylase that has been processed by proteolytic cleavage. http://purl.obolibrary.org/obo/UBERON_8410031 muscularis mucosae of appendix http://purl.obolibrary.org/obo/UBERON_0001239 muscularis mucosae of large intestine A muscularis mucosa that is part of a vermiform appendix. http://purl.obolibrary.org/obo/PR_000019700 dipeptidase 1 proteolytic cleavage product http://purl.obolibrary.org/obo/PR_000018264 proteolytic cleavage product A dipeptidase 1 that has been processed by proteolytic cleavage. http://purl.obolibrary.org/obo/UBERON_8410046 appendix smooth muscle circular layer http://purl.obolibrary.org/obo/UBERON_0012368 circular muscle layer of muscular coat A circular muscle layer of muscular coat that is part of a vermiform appendix smooth muscle. http://purl.obolibrary.org/obo/PR_000019734 endothelin-1 proteolytic cleavage product http://purl.obolibrary.org/obo/PR_000018264 proteolytic cleavage product An endothelin-1 that has been processed by proteolytic cleavage. http://purl.obolibrary.org/obo/UBERON_8410047 appendix smooth muscle longitudinal layer http://purl.obolibrary.org/obo/UBERON_0012369 longitudinal muscle layer of muscular coat A longitudinal muscle layer of muscular coat that is part of a vermiform appendix smooth muscle. http://purl.obolibrary.org/obo/PR_000019802 eosinophil peroxidase proteolytic cleavage product http://purl.obolibrary.org/obo/PR_000018264 proteolytic cleavage product An eosinophil peroxidase that has been processed by proteolytic cleavage. http://purl.obolibrary.org/obo/UBERON_8410052 lymph node germinal center light zone http://purl.obolibrary.org/obo/UBERON_0001744 lymphoid tissue Lymph node germinal centers contain two microenvironments: the light zone and the dark zone. The light zone is sparsely populated with B cells and includes additional cell types such as follicular dendritic cells, lymph node tingible macrophages and T follicular helper cells. http://purl.obolibrary.org/obo/PR_000019879 fibroblast growth factor 1 proteolytic cleavage product http://purl.obolibrary.org/obo/PR_000018264 proteolytic cleavage product A fibroblast growth factor 1 that has been processed by proteolytic cleavage. http://purl.obolibrary.org/obo/UBERON_8410053 lymph node germinal center dark zone http://purl.obolibrary.org/obo/UBERON_0001744 lymphoid tissue Lymph node germinal centers contain two microenvironments: the light zone and the dark zone. The dark zone is densely populated with B cell blasts and reticular cells. http://purl.obolibrary.org/obo/PR_000019882 fibroblast growth factor 2 proteolytic cleavage product http://purl.obolibrary.org/obo/PR_000018264 proteolytic cleavage product A fibroblast growth factor 2 that has been processed by proteolytic cleavage. http://purl.obolibrary.org/obo/CL_0009113 T follicular regulatory cell http://purl.obolibrary.org/obo/CL_0000815 regulatory T cell A regulatory T cell present in the B cell follicles and germinal centers of lymphoid tissues. In humans, it is CXCR5+. http://purl.obolibrary.org/obo/PR_000019959 galanin proteolytic cleavage product http://purl.obolibrary.org/obo/PR_000018264 proteolytic cleavage product A galanin that has been processed by proteolytic cleavage. http://purl.obolibrary.org/obo/CL_4029002 germline-derived nurse cell http://purl.obolibrary.org/obo/CL_4029001 gamete-nursing cell A gamete-nursing cell that derives from a germline cell (del Pino, 2021). http://purl.obolibrary.org/obo/PR_000020329 integrin alpha-IIb proteolytic cleavage product http://purl.obolibrary.org/obo/PR_000009127 integrin alpha-IIb An integrin alpha-IIb that has been processed by proteolytic cleavage. http://purl.obolibrary.org/obo/CL_0003047 M14 retinal ganglion cell http://purl.obolibrary.org/obo/CL_0003001 bistratified retinal ganglion cell A bistratifed retinal ganglion cell that has small, symmetric dendritic fields that terminate in S1 and S4-S5. http://purl.obolibrary.org/obo/PR_000020376 metastasis-suppressor KiSS-1 proteolytic cleavage product http://purl.obolibrary.org/obo/PR_000009344 metastasis-suppressor KiSS-1 A metastasis-suppressor KiSS-1 that has been processed by proteolytic cleavage. http://purl.obolibrary.org/obo/CL_0004250 bistratified retinal amacrine cell http://purl.obolibrary.org/obo/CL_0004247 bistratified cell An amicrine that stratifies dendrites at two and only two locations. http://purl.obolibrary.org/obo/PR_000020497 lactotransferrin proteolytic cleavage product http://purl.obolibrary.org/obo/PR_000009978 lactotransferrin A lactotransferrin that has been processed by proteolytic cleavage. http://purl.obolibrary.org/obo/CL_0003010 G7 retinal ganglion cell http://purl.obolibrary.org/obo/CL_0003001 bistratified retinal ganglion cell A bistratified retinal ganglion cell that has a dendrite field that terminates in sublaminar layer S2 and a second dendrite field that terminates in sublaminar layer S4. http://purl.obolibrary.org/obo/PR_000020631 myeloperoxidase proteolytic cleavage product http://purl.obolibrary.org/obo/PR_000010543 myeloperoxidase A myeloperoxidase that has been processed by proteolytic cleavage. http://purl.obolibrary.org/obo/CL_4030029 blood lymphocyte http://purl.obolibrary.org/obo/CL_2000001 peripheral blood mononuclear cell A lymphocyte located in blood. http://purl.obolibrary.org/obo/PR_000020735 nuclear factor NF-kappa-B p100 subunit proteolytic cleavage product http://purl.obolibrary.org/obo/PR_000011178 nuclear factor NF-kappa-B p100 subunit A nuclear factor NF-kappa-B p100 subunit that has been processed by proteolytic cleavage. http://purl.obolibrary.org/obo/CL_0003003 G2 retinal ganglion cell http://purl.obolibrary.org/obo/CL_0000740 retinal ganglion cell A mono-stratified retinal ganglion cell that has a small dendritic field and a sparse dendritic arbor with post sympatic terminals in sublaminar layer S3. http://purl.obolibrary.org/obo/PR_000020789 neuropeptide Y proteolytic cleavage product http://purl.obolibrary.org/obo/PR_000011387 neuropeptide Y A neuropeptide Y that has been processed by proteolytic cleavage. http://purl.obolibrary.org/obo/CL_0004222 flag B amacrine cell http://purl.obolibrary.org/obo/CL_4030028 glycinergic amacrine cell A flag amacrine cell with post-synaptic terminals in S3, S4, and S5. This cell type releases the neurotransmitter glycine. http://purl.obolibrary.org/obo/PR_000020916 proenkephalin-B proteolytic cleavage product http://purl.obolibrary.org/obo/PR_000012526 proenkephalin-B A proenkephalin-B that has been processed by proteolytic cleavage. http://purl.obolibrary.org/obo/CL_0004232 starburst amacrine cell http://purl.obolibrary.org/obo/CL_0008061 GABA-Chol neuron An amacrine cell with a flat dendritic arbor and a medium dendritic field. Starburst amacrine cells have post-synaptic terminals in S2. This cell type releases the neurotransmitters gamma-aminobutyric acid (GABA) and acetylcholine. http://purl.obolibrary.org/obo/PR_000020924 proenkephalin-A proteolytic cleavage product http://purl.obolibrary.org/obo/PR_000012544 proenkephalin-A A proenkephalin-A that has been processed by proteolytic cleavage. http://purl.obolibrary.org/obo/CL_0003007 G4-OFF retinal ganglion cell http://purl.obolibrary.org/obo/CL_0003005 G4 retinal ganglion cell A G4 retinal ganglion cell that has post sympatic terminals in sublaminar layers S2 and S3 and is depolarized by decreased illumination of their receptive field center http://purl.obolibrary.org/obo/PR_000021036 pro-opiomelanocortin proteolytic cleavage product http://purl.obolibrary.org/obo/PR_000013015 pro-opiomelanocortin A pro-opiomelanocortin that has been processed by proteolytic cleavage. http://purl.obolibrary.org/obo/CL_0004224 AB diffuse-2 amacrine cell http://purl.obolibrary.org/obo/CL_4030028 glycinergic amacrine cell A broadly stratifying amacrine cell that has a small dendritic field and post-synaptic terminals in S2 and S3. This cell type releases the neurotransmitter glycine. http://purl.obolibrary.org/obo/PR_A2VEC9 SCO-spondin (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A SCO-spondin that is encoded in the genome of human. http://purl.obolibrary.org/obo/CL_0004213 type 3a cone bipolar cell http://purl.obolibrary.org/obo/CL_0000755 type 3 cone bipolar cell (sensu Mus) A type of type 3 cone bipolar cell with distinctive curly dendrites. http://purl.obolibrary.org/obo/PR_O15389 sialic acid-binding Ig-like lectin 5 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A sialic acid-binding Ig-like lectin 5 that is encoded in the genome of human. http://purl.obolibrary.org/obo/CL_0003028 M1 retinal ganglion cell http://purl.obolibrary.org/obo/CL_0000740 retinal ganglion cell A monostratified retinal ganglion cell that has a small dendrite field with a dense dendrite arbor with post synaptic terminals in sublaminer layer S4. http://purl.obolibrary.org/obo/PR_O43699 sialic acid-binding Ig-like lectin 6 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A sialic acid-binding Ig-like lectin 6 that is encoded in the genome of human. http://purl.obolibrary.org/obo/CL_0004229 A2-like amacrine cell http://purl.obolibrary.org/obo/CL_0004251 narrow field retinal amacrine cell A bistratified amacrine cell with a small dendritic field that has dendrite stratification in S2, and in S3 and S4. http://purl.obolibrary.org/obo/PR_O76036 natural cytotoxicity triggering receptor 1 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A natural cytotoxicity triggering receptor 1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_O95944 natural cytotoxicity triggering receptor 2 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A natural cytotoxicity triggering receptor 2 that is encoded in the genome of human. http://purl.obolibrary.org/obo/CL_0003009 G6 retinal ganglion cell http://purl.obolibrary.org/obo/CL_0000740 retinal ganglion cell A mono-stratified retinal ganglion cell that has a medium dendritic field and a sparse dendritic arbor with post sympatic terminals in sublaminar layer S4 and S5. http://purl.obolibrary.org/obo/PR_P00797 renin (human) http://purl.obolibrary.org/obo/PR_000013883 renin A renin that is encoded in the genome of human. http://purl.obolibrary.org/obo/CL_0003014 G11 retinal ganglion cell http://purl.obolibrary.org/obo/CL_0000740 retinal ganglion cell A mono-stratified retinal ganglion cell that has a large dendritic field, a medium dendritic arbor, and a medium length secondary dendrite shaft. http://purl.obolibrary.org/obo/PR_P01100 protein c-Fos (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A protein c-Fos that is encoded in the genome of human. http://purl.obolibrary.org/obo/CL_0004226 monostratified amacrine cell http://purl.obolibrary.org/obo/CL_0004246 monostratified cell An amacrine cell with a small dendritic field with post-synaptic terminals in S3 and S4. http://purl.obolibrary.org/obo/PR_P01236 prolactin (human) http://purl.obolibrary.org/obo/PR_000013246 prolactin A prolactin that is encoded in the genome of human. http://purl.obolibrary.org/obo/CL_0004001 local interneuron http://purl.obolibrary.org/obo/CL_0000099 interneuron An interneuron whose axon stays entirely within the gray matter region where the cell body resides. http://purl.obolibrary.org/obo/PR_P01308 preproinsulin (human) http://purl.obolibrary.org/obo/PR_000009054 preproinsulin A preproinsulin that is encoded in the genome of human. http://purl.obolibrary.org/obo/CL_0003048 L cone cell http://purl.obolibrary.org/obo/CL_0000573 retinal cone cell A cone cell that detects long wavelength light. Exact peak of spectra detected differs between species. In humans, spectra peaks at 564-580 nm. http://purl.obolibrary.org/obo/PR_P01589 interleukin-2 receptor subunit alpha (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein An interleukin-2 receptor subunit alpha that is encoded in the genome of human. http://purl.obolibrary.org/obo/CL_0004116 retinal ganglion cell C http://purl.obolibrary.org/obo/CL_0000740 retinal ganglion cell A retinal ganglion with cell medium cell bodies and medium to large dendritic fields. http://purl.obolibrary.org/obo/PR_P02788 lactotransferrin (human) http://purl.obolibrary.org/obo/PR_000009978 lactotransferrin A lactotransferrin that is encoded in the genome of human. http://purl.obolibrary.org/obo/CL_0004162 360 nm-cone http://purl.obolibrary.org/obo/CL_0003051 UV cone cell A cone whose sensitivity measurements have an average spectral peak of 358.2 nm. These cones are described in rat. http://purl.obolibrary.org/obo/PR_P04271 protein S100-B (human) http://purl.obolibrary.org/obo/PR_000014419 protein S100-B A protein S100-B that is encoded in the genome of human. http://purl.obolibrary.org/obo/CL_4023057 cerebellar inhibitory GABAergic interneuron http://purl.obolibrary.org/obo/CL_1001611 cerebellar neuron A GABAergic interneuron whose soma is located in the cerebellar cortex. http://purl.obolibrary.org/obo/PR_P07101 tyrosine 3-monooxygenase (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A tyrosine 3-monooxygenase that is encoded in the genome of human. http://purl.obolibrary.org/obo/CL_4023060 hippocampal CA1-3 neuron http://purl.obolibrary.org/obo/CL_0002608 hippocampal neuron A neuron that has its soma located in CA1-3 of the hippocampus. http://purl.obolibrary.org/obo/PR_P07204 thrombomodulin (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A thrombomodulin that is encoded in the genome of human. http://purl.obolibrary.org/obo/CL_4023063 medial ganglionic eminence derived interneuron http://purl.obolibrary.org/obo/CL_0000099 interneuron An interneuron that is derived from the medial ganglionic eminence. In mice and humans, it expresses LHX6 and SOX6. http://purl.obolibrary.org/obo/PR_P07333 macrophage colony-stimulating factor 1 receptor (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A macrophage colony-stimulating factor 1 receptor that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_8480025 skin of clavicle region http://purl.obolibrary.org/obo/UBERON_0000014 zone of skin A zone of skin that is above the clavicle zone in the pectoral girdle region. http://purl.obolibrary.org/obo/PR_P08575 receptor-type tyrosine-protein phosphatase C (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A receptor-type tyrosine-protein phosphatase C that is encoded in the genome of human. http://purl.obolibrary.org/obo/CL_4033002 neuroendocrine cell of epithelium of crypt of Lieberkuhn http://purl.obolibrary.org/obo/CL_1001516 intestinal enteroendocrine cell A(n) neuroendocrine cell that is part of a(n) epithelium of crypt of Lieberkuhn. http://purl.obolibrary.org/obo/PR_P10721 mast/stem cell growth factor receptor Kit (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A mast/stem cell growth factor receptor that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_8850000 lumen of pulmonary alveolus http://purl.obolibrary.org/obo/UBERON_0002553 anatomical cavity An anatomical cavity that is part of the alveolus of the lung http://purl.obolibrary.org/obo/PR_P12314 high affinity immunoglobulin gamma Fc receptor I (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A high affinity immunoglobulin gamma Fc receptor I that is encoded in the genome of human. http://purl.obolibrary.org/obo/CL_4033068 cycling B cell http://purl.obolibrary.org/obo/CL_0000236 B cell A(n) B cell that is cycling. http://purl.obolibrary.org/obo/PR_P12319 high affinity immunoglobulin epsilon receptor subunit alpha (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A high affinity immunoglobulin epsilon receptor subunit alpha that is encoded in the genome of human. http://purl.obolibrary.org/obo/CL_4033069 cycling T cell http://purl.obolibrary.org/obo/CL_0000084 T cell A(n) T cell that is cycling. http://purl.obolibrary.org/obo/PR_P13591 neural cell adhesion molecule 1 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A neural cell adhesion molecule 1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P13612 integrin alpha-4 (human) http://purl.obolibrary.org/obo/PR_000009129 integrin alpha-4 An integrin alpha-4 that is encoded in the genome of human. http://purl.obolibrary.org/obo/CL_4033070 cycling dendritic cell http://purl.obolibrary.org/obo/CL_4033078 cycling mononuclear phagocyte A(n) dendritic cell that is cycling. http://purl.obolibrary.org/obo/PR_P14784 interleukin-2 receptor subunit beta (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein An interleukin-2 receptor subunit beta that is encoded in the genome of human. http://purl.obolibrary.org/obo/CL_4033071 cycling natural killer cell http://purl.obolibrary.org/obo/CL_0000623 natural killer cell A(n) natural killer cell that is cycling. http://purl.obolibrary.org/obo/PR_P16109 P-selectin (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A P-selectin that is encoded in the genome of human. http://purl.obolibrary.org/obo/CL_4033072 cycling gamma-delta T cell http://purl.obolibrary.org/obo/CL_4033069 cycling T cell A(n) gamma-delta T cell that is cycling. http://purl.obolibrary.org/obo/PR_P16150 leukosialin (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A leukosialin that is encoded in the genome of human. http://purl.obolibrary.org/obo/CL_4033073 cycling monocyte http://purl.obolibrary.org/obo/CL_4033081 cycling myeloid cell A(n) monocyte that is cycling. http://purl.obolibrary.org/obo/PR_P16234 platelet-derived growth factor receptor alpha (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein An alpha-type platelet-derived growth factor receptor that is encoded in the genome of human. http://purl.obolibrary.org/obo/CL_4033074 cycling CD8-positive, alpha-beta T cell http://purl.obolibrary.org/obo/CL_4033069 cycling T cell A(n) CD8-positive, alpha-beta T cell that is cycling. http://purl.obolibrary.org/obo/PR_P16410 cytotoxic T-lymphocyte protein 4 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A cytotoxic T-lymphocyte protein 4 that is encoded in the genome of human. http://purl.obolibrary.org/obo/CL_4033075 cycling CD4-positive, alpha-beta T cell http://purl.obolibrary.org/obo/CL_4033069 cycling T cell A(n) CD4-positive, alpha-beta T cell that is cycling. http://purl.obolibrary.org/obo/PR_P16871 interleukin-7 receptor subunit alpha (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein An interleukin-7 receptor subunit alpha that is encoded in the genome of human. http://purl.obolibrary.org/obo/CL_4033076 cycling macrophage http://purl.obolibrary.org/obo/CL_4033081 cycling myeloid cell A(n) macrophage that is cycling. http://purl.obolibrary.org/obo/PR_P17301 integrin alpha-2 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein An integrin alpha-2 that is encoded in the genome of human. http://purl.obolibrary.org/obo/CL_4033077 cycling alveolar macrophage http://purl.obolibrary.org/obo/CL_4033076 cycling macrophage A(n) alveolar macrophage that is cycling. http://purl.obolibrary.org/obo/PR_P17927 complement receptor type 1 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A complement receptor type 1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/CL_4033078 cycling mononuclear phagocyte http://purl.obolibrary.org/obo/CL_0000113 mononuclear phagocyte A(n) mononuclear phagocyte that is cycling. http://purl.obolibrary.org/obo/PR_P18827 syndecan-1 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A syndecan-1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/CL_4033079 cycling endothelial cell of lymphatic vessel http://purl.obolibrary.org/obo/CL_0002138 endothelial cell of lymphatic vessel A(n) endothelial cell of lymphatic vessel that is cycling. http://purl.obolibrary.org/obo/PR_P20702 integrin alpha-X (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein An integrin alpha-X that is encoded in the genome of human. http://purl.obolibrary.org/obo/CL_4033080 cycling pulmonary alveolar type 2 cell http://purl.obolibrary.org/obo/CL_0002063 pulmonary alveolar type 2 cell A(n) pulmonary alveolar type 2 cell that is cycling. http://purl.obolibrary.org/obo/PR_P21781 fibroblast growth factor 7 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A fibroblast growth factor 7 that is encoded in the genome of human. http://purl.obolibrary.org/obo/CL_4033081 cycling myeloid cell http://purl.obolibrary.org/obo/CL_0000763 myeloid cell A(n) myeloid cell that is cycling. http://purl.obolibrary.org/obo/PR_P22897 macrophage mannose receptor 1 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A macrophage mannose receptor 1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/CL_4033082 cycling basal cell http://purl.obolibrary.org/obo/CL_0000646 basal cell A(n) basal cell that is cycling. http://purl.obolibrary.org/obo/PR_P23771 trans-acting T-cell-specific transcription factor GATA-3 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A trans-acting T-cell-specific transcription factor GATA-3 that is encoded in the genome of human. http://purl.obolibrary.org/obo/CL_4042014 spiny VIP neuron http://purl.obolibrary.org/obo/CL_4023016 VIP GABAergic interneuron A VIP GABAergic cortical interneuron with a soma located in L1-3 of some neocortex in Mmus. This neuron has a multipolar morphology with spiny dendrites concentrating on L1 of the cortex, and has a burst firing electrophysiological signature with highly dynamic dendritic spines. http://purl.obolibrary.org/obo/PR_P26951 interleukin-3 receptor subunit alpha (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein An interleukin-3 receptor class 2 alpha chain that is encoded in the genome of human. http://purl.obolibrary.org/obo/CL_4042015 VIP-ChAT interneuron http://purl.obolibrary.org/obo/CL_0008061 GABA-Chol neuron A VIP GABAergic cortical interneuron expressing vasoactive intestinal polypeptide and choline acetyltransferase in the Mmus neocortex. This interneuron releases both γ-aminobutyric acid and acetylcholine. http://purl.obolibrary.org/obo/PR_P31994 low affinity immunoglobulin gamma Fc region receptor II-b (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A low affinity immunoglobulin gamma Fc region receptor II-b that is encoded in the genome of human. http://purl.obolibrary.org/obo/CL_4042016 nasal serous secreting cell http://purl.obolibrary.org/obo/CL_0000313 serous secreting cell A serous secreting cell that is part of a submucosal gland in the nasal cavity respiratory epithelium. http://purl.obolibrary.org/obo/PR_P36888 receptor-type tyrosine-protein kinase FLT3 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A receptor-type tyrosine-protein kinase FLT3 that is encoded in the genome of human. http://purl.obolibrary.org/obo/CL_4047001 cycling stromal cell http://purl.obolibrary.org/obo/CL_0000499 stromal cell A(n) stromal cell that is cycling. http://purl.obolibrary.org/obo/PR_P51884 lumican (human) http://purl.obolibrary.org/obo/PR_000009981 lumican A lumican that is encoded in the genome of human. http://purl.obolibrary.org/obo/CL_4047002 cycling glial cell http://purl.obolibrary.org/obo/CL_0000125 glial cell A(n) glial cell that is cycling. http://purl.obolibrary.org/obo/PR_P56199 integrin alpha-1 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein An integrin alpha-1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/CL_4047003 cycling plasma cell http://purl.obolibrary.org/obo/CL_0000786 plasma cell A(n) plasma cell that is cycling. http://purl.obolibrary.org/obo/PR_P59901 leukocyte immunoglobulin-like receptor subfamily A member 4 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A leukocyte immunoglobulin-like receptor subfamily A member 4 that is encoded in the genome of human. http://purl.obolibrary.org/obo/CL_4047004 cycling type EC enteroendocrine cell http://purl.obolibrary.org/obo/CL_0000577 type EC enteroendocrine cell A(n) type EC enteroendocrine cell that is cycling. http://purl.obolibrary.org/obo/PR_P78324 tyrosine-protein phosphatase non-receptor type substrate 1 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A tyrosine-protein phosphatase non-receptor type substrate 1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/CL_4047005 cycling neuroblast (sensu Vertebrata) http://purl.obolibrary.org/obo/CL_0000031 neuroblast (sensu Vertebrata) A(n) neuroblast (sensu Vertebrata) that is cycling. http://purl.obolibrary.org/obo/PR_P78509 reelin (human) http://purl.obolibrary.org/obo/PR_000013879 reelin A reelin that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_8600138 stomach lamina propria http://purl.obolibrary.org/obo/UBERON_0004780 gastrointestinal system lamina propria The lamina propria that underlies the epithelial lining of the stomach. http://purl.obolibrary.org/obo/PR_P80188 neutrophil gelatinase-associated lipocalin (human) http://purl.obolibrary.org/obo/PR_000009725 neutrophil gelatinase-associated lipocalin A neutrophil gelatinase-associated lipocalin that is encoded in the genome of human. http://purl.obolibrary.org/obo/CL_4300353 Purkinje cell (Mmus) http://purl.obolibrary.org/obo/CL_4300028 cerebellar GABAergic neuron (Mmus) A Purkinje cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Pcp2 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Subclass:313 CBX Purkinje Gaba. http://purl.obolibrary.org/obo/PR_Q01344 interleukin-5 receptor subunit alpha (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein An interleukin-5 receptor subunit alpha that is encoded in the genome of human. http://purl.obolibrary.org/obo/CL_0020017 M0 macrophage http://purl.obolibrary.org/obo/CL_0000235 macrophage A macrophage that has not yet undergone polarization into a specific macrophage subtype. These cells are non-activated and have the potential to differentiate into inflammatory (M1) or alternatively activated (M2) macrophage subtypes in response to appropriate stimuli. http://purl.obolibrary.org/obo/PR_Q01638 interleukin-1 receptor-like 1 (human) http://purl.obolibrary.org/obo/PR_000008994 interleukin-1 receptor-like 1 An interleukin-1 receptor-like 1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/CL_4052108 IgD-negative class switched memory B cell http://purl.obolibrary.org/obo/CL_0001053 IgD-negative memory B cell A class switched memory B cell that lacks IgD on the cell surface. http://purl.obolibrary.org/obo/PR_Q03405 urokinase plasminogen activator surface receptor (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A urokinase plasminogen activator surface receptor that is encoded in the genome of human. http://purl.obolibrary.org/obo/CL_0020016 osteochondral skeletal stem cell http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell A tissue-specific stem cell with long-term self-renewal capacity that is restricted to generating bone, cartilage, and stromal cell lineages. This cell is primarily located in the growth plate (resting zone), periosteum, and subchondral bone regions, and is marked by high clonogenicity and robust multipotent differentiation potential in both osteogenic and chondrogenic lineages. Distinctively, ocSSC lacks adipogenic capacity, distinguishing it from other mesenchymal stem cell populations. http://purl.obolibrary.org/obo/PR_Q12866 tyrosine-protein kinase Mer (human) http://purl.obolibrary.org/obo/PR_000010329 tyrosine-protein kinase Mer A tyrosine-protein kinase Mer that is encoded in the genome of human. http://purl.obolibrary.org/obo/CL_0020018 proliferative fibrochondrocyte http://purl.obolibrary.org/obo/CL_4072104 fibrochondrocyte A fibrochondrocyte located in fibrocartilage that exhibits active proliferation capacity and is in S phase of the cell cycle. It functions as a progenitor cell positioned at the root of developmental trajectories alongside fibrochondrocyte progenitors (FCP), with the capacity to diverge toward one of two developmental fates: (1) fibrochondrocytes and prehypertrophic chondrocytes, or (2) regulatory chondrocytes and prehypertrophic chondrocytes. It is characterised by co-expression of COL1A1, the growth factors FGF7 and CTGF, and the cell-cycle genes STMN1, KIAA0101, and MCM3 in humans. During early progenitor differentiation, FGF7 and COL1A1 expression increases and then declines as the cell commits to terminal fates. http://purl.obolibrary.org/obo/PR_Q15116 programmed cell death protein 1 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A programmed cell death protein 1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/CL_4072104 fibrochondrocyte http://purl.obolibrary.org/obo/CL_0000138 chondrocyte A chondrocyte with hybrid fibroblastic-chondrogenic characteristics found in fibrocartilage, particularly in the avascular inner zone and transitional middle zone of the meniscus. In humans, fibrochondrocytes are marked by predominant expression of type I collagen (COL1A1) and fibril-associated collagens (COL3A1, COL6A1), while retaining type II collagen (COL2A1) expression and exhibiting lower SOX9 than hyaline chondrocytes. This molecular profile underlies the synthesis of abundant type I collagen essential for fibrocartilage matrix and reflects an intermediate phenotype between fibroblast and chondrocyte. http://purl.obolibrary.org/obo/PR_Q9BZZ2 sialoadhesin (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A sialoadhesin that is encoded in the genome of human. http://purl.obolibrary.org/obo/CL_0020019 regulatory chondrocyte http://purl.obolibrary.org/obo/CL_0000138 chondrocyte A chondrocyte located mainly in the superficial zone of articular cartilage. In healthy human cartilage, regulatory chondrocytes are characterized by expression of EIF5A, PGK1, ANXA1, and TUBA1A. During osteoarthritis, a distinct subpopulation expands, marked by high expression of CHI3L1, CHI3L2, CRTAC1, and AEBP1, with enrichment for signaling pathway regulation (including Toll-like receptor, mTOR, and TGF-beta signaling) and antigen-processing gene expression, with a small proportion expressing MHC class II genes, suggesting potential immune cell-like regulatory functions during osteoarthritis progression. http://purl.obolibrary.org/obo/PR_Q9HCB6 spondin-1 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A spondin-1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/CL_0020020 homeostatic chondrocyte http://purl.obolibrary.org/obo/CL_0000138 chondrocyte A chondrocyte identified in both healthy and osteoarthritic human articular cartilage, and in intervertebral disc tissue. In healthy articular cartilage, a homeostatic chondrocyte is characterised by the expression of TXNIP, IFITM3, GDF15, and TIMP1 (Wang et al., 2021), among other extracellular matrix and regulatory molecules. This cell maintains cartilage integrity by producing key ECM components and supporting baseline tissue homeostasis. In OA cartilage, this cell is enriched for genes related to cellular homeostasis modulation, including regulation of the cell cycle, development, and RNA metabolism (Ji et al., 2018). http://purl.obolibrary.org/obo/PR_Q9NRM6 interleukin-17 receptor B (human) http://purl.obolibrary.org/obo/PR_000008982 interleukin-17 receptor B An interleukin-17 receptor B that is encoded in the genome of human. http://purl.obolibrary.org/obo/CL_0020021 fibrochondrocyte progenitor cell http://purl.obolibrary.org/obo/CL_0008019 mesenchymal cell A mesenchymal progenitor cell located in fibrocartilaginous tissues, along the fibrochondrocytic differentiation pathway that co-expresses both fibrochondrocyte markers (COL1A1, COL3A1) and mesenchymal stem cell markers (MCAM/CD146, MYLK) in humans. This cell serves as a progenitor for mature fibrochondrocytes and other meniscal cell types, with differentiation regulated by TGF-β signaling, focal adhesion, and extracellular matrix-receptor interaction pathways. http://purl.obolibrary.org/obo/PR_Q9NZC2 triggering receptor expressed on myeloid cells 2 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A triggering receptor expressed on myeloid cells 2 that is encoded in the genome of human. http://purl.obolibrary.org/obo/CL_0020022 prehypertrophic chondrocyte http://purl.obolibrary.org/obo/CL_0000138 chondrocyte A post-proliferative chondrocyte in the prehypertrophic zone of the cartilage tissue, located between the proliferative and hypertrophic zones. This cell is characterised by increased cell volume and expression of Indian Hedgehog (Ihh), PTH1R, and Runx2/3 in both humans and mice (Hallett et al., 2021). It coordinates the PTHrP-Ihh feedback loop that regulates chondrocyte differentiation and functions as a signalling hub for communication between proliferative chondrocytes, hypertrophic chondrocytes, and periosteal osteoblasts (Hallett et al., 2021). http://purl.obolibrary.org/obo/PR_Q9Y6Q6 tumor necrosis factor receptor superfamily member 11A (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A tumor necrosis factor receptor superfamily member 11A that is encoded in the genome of human. http://purl.obolibrary.org/obo/CL_0020023 effector chondrocyte http://purl.obolibrary.org/obo/CL_0000138 chondrocyte A metabolically highly active chondrocyte that is identified in the cartilaginous tissues, including articular cartilage and intervertebral disc cartilage. In the human articular cartilage, this cell is marked by genes such as CYTL1, FRZB, CLEC3A, and S100B (Ji et al., 2018; Raut et al.,2025). This cell demonstrates strong metabolic activity and is implicated in extracellular matrix regulation and adaptive responses (Ji et al., 2018; Gan et al., 2021; Raut et al.,2025). http://purl.obolibrary.org/obo/PR_O76070 gamma-synuclein (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A gamma-synuclein that is encoded in the genome of human. http://purl.obolibrary.org/obo/CL_0020024 alpha retinal ganglion cell OFF-sustained (Mmus) http://purl.obolibrary.org/obo/CL_0004117 alpha retinal ganglion cell (Mmus) A mouse retinal ganglion cell type defined by a large soma and a wide, monostratified dendritic arbor that stratifies just distal to the outer ChAT band of the inner plexiform layer (Krieger et al., 2017). It corresponds to the G5 physiological type (Baden et al., 2016; Goetz et al., 2022) and the C42 transcriptomic cluster (Tran et al., 2019), and is considered the evolutionary ortholog of the primate OFF midget RGC (Hahn et al., 2023). The cell projects a thick, fast-conducting axon to the dorsal lateral geniculate nucleus and superior colliculus. It shows a sustained increase in firing to light decrements with a slow decay time constant of roughly 250 ms and a large receptive field center with weak surround antagonism (Krieger et al., 2017). Its molecular profile includes expression of Spp1 and Neurofilament (Smi32) together with Brn3a (Pou4f1) and Brn3b (Pou4f2), absence of Brn3c (Pou4f3) and Calbindin (Calb1), and strong enrichment of Fes (Krieger et al., 2017; Tran et al., 2019). http://purl.obolibrary.org/obo/PR_O88324 CD83 antigen (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A CD83 molecule that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/CL_0020025 alpha retinal ganglion cell ON-sustained (Mmus) http://purl.obolibrary.org/obo/CL_4023032 ON retinal ganglion cell A retinal ganglion cell type that has a large soma and a wide, monostratified dendritic arbor that stratifies in the inner sublamina of the inner plexiform layer, with dendrites located just proximal to the inner ChAT band (Krieger et al., 2017). It shows a sustained increase in firing rate to ON stimuli (Krieger et al., 2017). It corresponds to the G24 functional type (Baden et al., 2016; Goetz et al., 2022), the C43 transcriptomic cluster (Tran et al., 2019), and is considered the mouse ortholog of the primate ON midget retinal ganglion cell (Hahn et al., 2023). It is molecularly defined by expression of Spp1, Smi32, Brn3b, Calbindin, and Tbr2 (Krieger et al., 2017; Tran et al., 2019). http://purl.obolibrary.org/obo/PR_O88410 C-X-C chemokine receptor type 3 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A C-X-C chemokine receptor type 3 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P24807 signal transducer CD24 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A signal transducer CD24 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/CL_0020026 alpha retinal ganglion cell OFF-transient (Mmus) http://purl.obolibrary.org/obo/CL_0004117 alpha retinal ganglion cell (Mmus) An alpha retinal ganglion cell subtype found in the mouse retina that responds selectively and transiently to decreases in light intensity. It is characterized by a large soma, a broad dendritic arbor that stratifies within sublamina a of the inner plexiform layer, and rapid OFF-transient firing kinetics that decay even during sustained stimulation (Krieger et al., 2017). Functionally, it corresponds to G8 in the Baden functional classification (Baden et al., 2016; Goetz et al., 2022) and C45 in the Tran transcriptomic atlas (Tran et al., 2019), and it is considered the evolutionary ortholog of the primate OFF Parasol RGC (Hahn et al., 2023). This cell type acts as a detector of rapidly approaching dark objects and contributes to innate defensive responses by encoding looming stimuli (Münch et al., 2009). It exhibits a distinctive molecular signature by its expression of Brn3c (Krieger et al., 2017). http://purl.obolibrary.org/obo/PR_P25024 C-X-C chemokine receptor type 1 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A C-X-C chemokine receptor type 1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P25025 C-X-C chemokine receptor type 2 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A C-X-C chemokine receptor type 2 that is encoded in the genome of human. http://purl.obolibrary.org/obo/CL_0020027 alpha retinal ganglion cell ON-transient (Mmus) http://purl.obolibrary.org/obo/CL_4023032 ON retinal ganglion cell An alpha retinal ganglion cell subtype in the mouse retina that responds selectively and transiently to increases in light intensity. It possesses the large soma and expansive dendritic field characteristic of alpha RGCs (Krieger et al., 2017). This cell exhibits a brief, fast-decaying burst of firing at the onset of light increments and contributes to motion detection for luminance increases, forming the ON-branch of the transient magnocellular-like pathway (Krieger et al., 2017; Hahn et al., 2023). Functionally, it corresponds to cluster G19 and aligns transcriptomically with cluster C41 (Krieger et al., 2017; Tran et al., 2019). It is orthologous to the primate ON Parasol RGC (Hahn et al., 2023). Molecularly, it expresses Spp1, Smi32, and Brn3b, but lacks Brn3a, Brn3c, and Calbindin (Krieger et al., 2017). http://purl.obolibrary.org/obo/PR_P25063 signal transducer CD24 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A signal transducer CD24 that is encoded in the genome of human. http://purl.obolibrary.org/obo/CL_0020059 serous demilune cell of salivary gland http://purl.obolibrary.org/obo/CL_0000313 serous secreting cell A serous secreting cell that is part of a salivary gland, forming crescent-shaped (demilune) caps at the distal ends of mucous acini in mixed glands. Prominent in human submandibular and sublingual glands, this cell delivers its watery, enzyme-rich secretions including alpha-amylase through intercellular canaliculi that run between adjacent mucous cells to reach the acinar lumen (Amano et al., 2012). In rodents, these cells also express neuronal nitric oxide synthase (nNOS). http://purl.obolibrary.org/obo/PR_P25918 B-lymphocyte antigen CD19 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A CD19 molecule that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/CL_0020060 basal duct cell of salivary gland http://purl.obolibrary.org/obo/CL_0000646 basal cell A basal cell that is part of the duct of a salivary gland, characterized by an undifferentiated phenotype, expression of KRT5, and a position surrounding the striated ductal epithelium. This cell is presumed to function as a salivary gland stem/progenitor cell capable of regenerating ductal and potentially acinar cell populations (Yura and Hamada, 2023). In mice, Lgr5-expressing cells within this compartment demonstrate tripotent capacity, able to generate acinar, ductal, and myoepithelial cell lineages. http://purl.obolibrary.org/obo/PR_P26010 integrin beta-7 (human) http://purl.obolibrary.org/obo/PR_000009143 integrin beta-7 An integrin beta-7 that is encoded in the genome of human. http://purl.obolibrary.org/obo/CL_0020061 periductal fibroblast of salivary gland http://purl.obolibrary.org/obo/CL_0000057 fibroblast A fibroblast that is part of the stroma of a salivary gland, positioned in the periductal connective tissue surrounding the ductal system. This cell maintains the extracellular matrix framework around salivary gland ducts and participates in immunomodulatory signaling. In the context of Sjögren's syndrome, periductal fibroblasts respond to IL-13 stimulation by upregulating VCAM-1, PDPN, and ICAM-1, contributing to the formation of tertiary lymphoid structures (Nayar et al., 2019). http://purl.obolibrary.org/obo/PR_P26011 integrin beta-7 (mouse) http://purl.obolibrary.org/obo/PR_000009143 integrin beta-7 An integrin beta-7 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P26151 high affinity immunoglobulin gamma Fc receptor I (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A high affinity immunoglobulin gamma Fc receptor I that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/CL_0020062 junctional epithelial cell http://purl.obolibrary.org/obo/CL_0002251 epithelial cell of alimentary canal An epithelial cell that is part of the junctional epithelium of the gingiva, forming a collar-like band around the cervix of the tooth. This cell attaches to the tooth surface via hemidesmosomes and an internal basal lamina rich in laminin-332 and ODAM (Gavriiloglou et al., 2024). The junctional epithelium is a stratified squamous non-keratinized epithelium ranging from 15-30 cell layers coronally to 1-3 cell layers apically. This cell expresses cytokeratin 19 (CK19) as a specific marker, along with ODAM and FDC-SP, and participates in innate immune defense by producing IL-8, IL-1alpha, and MMP-7, facilitating the transmigration of polymorphonuclear leukocytes through the epithelium (Gavriiloglou et al., 2024). This cell has a high turnover rate, with complete renewal occurring every 4-6 days (Lin et al., 2025), and develops from the reduced enamel epithelium during tooth eruption, although it can regenerate de novo without this precursor. http://purl.obolibrary.org/obo/PR_P26367 paired box protein Pax-6 (human) http://purl.obolibrary.org/obo/PR_000012318 paired box protein Pax-6 A paired box protein Pax-6 that is encoded in the genome of human. http://purl.obolibrary.org/obo/CL_0020063 tuft cell of parotid gland http://purl.obolibrary.org/obo/CL_0002204 tuft cell A tuft cell that is part of the epithelium of the parotid gland, localized to the striated ducts and never observed in acini. This cell is characterized by expression of POU2F3 and is expected to possess chemosensory function consistent with tuft cells in other tissues. Immunohistochemical analysis of normal human parotid gland tissue detected POU2F3-positive cells as a very rare population within the ductal compartment, positioned on the luminal side (Hoki et al., 2024). http://purl.obolibrary.org/obo/PR_P26618 platelet-derived growth factor receptor alpha (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein An alpha-type platelet-derived growth factor receptor that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/CL_0020064 tuft cell of sublingual gland http://purl.obolibrary.org/obo/CL_0002251 epithelial cell of alimentary canal A tuft cell that is part of the epithelium of the sublingual gland, localized to the ductal compartment. This cell is characterized by expression of POU2F3, consistent with tuft cell identity. Immunohistochemical analysis detected POU2F3-positive cells in normal human sublingual gland tissue (Hoki et al., 2024). http://purl.obolibrary.org/obo/PR_P26715 NKG2-A/NKG2-B type II integral membrane protein (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein An NKG2-A/NKG2-B type II integral membrane protein that is encoded in the genome of human. http://purl.obolibrary.org/obo/CL_0020065 ionocyte of salivary gland http://purl.obolibrary.org/obo/CL_0005006 ionocyte An ionocyte that is part of a salivary gland, localized to the ductal compartment on the luminal side. This specialized epithelial cell is characterized by expression of FOXI1 and is involved in regulating and maintaining osmotic pressure within the glandular environment (Dong et al., 2024). In normal human salivary glands, FOXI1-positive cells constitute less than 5% of ductal epithelial cells and are found exclusively in ducts, never in acini, across all major gland types including parotid, submandibular, sublingual, and minor salivary glands (Hoki et al., 2024). Like ionocytes in other tissues, this cell is expected to express high levels of CFTR and possess abundant mitochondria and ion transporters. http://purl.obolibrary.org/obo/PR_P26952 interleukin-3 receptor subunit alpha (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein An interleukin-3 receptor class 2 alpha chain that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P27548 CD40 ligand (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A tumor necrosis factor ligand superfamily member 5 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/CL_0020066 myoepithelial cell of salivary gland http://purl.obolibrary.org/obo/CL_0000185 myoepithelial cell A myoepithelial cell that is part of a salivary gland, positioned between the basal lamina and the secretory or ductal epithelial cells surrounding acini and intercalated ducts. This cell adopts a stellate morphology with four to eight cellular processes around acini and an elongated form parallel to the ductal axis around intercalated ducts (Amano et al., 2012). It expresses alpha-smooth muscle actin (ACTA2/alpha-SMA) as a primary marker, along with p63 and aquaporin 1 (AQP1), and contracts rhythmically in response to neural stimulation to facilitate saliva expulsion from secretory acini into the ductal system (Amano et al., 2012). This cell also produces FGF7, which activates FGFR2b-dependent transcriptional programs essential for seromucous acinar cell differentiation (Aure et al., 2023). In mice, myoepithelial cells express SOX2 and possess regenerative capacity, contributing to acinar cell restoration during tissue repair after severe injury. http://purl.obolibrary.org/obo/PR_P27814 killer cell lectin-like receptor subfamily B member 1C (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A killer cell lectin-like receptor subfamily B member 1C that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/GO_0000001 mitochondrion inheritance http://purl.obolibrary.org/obo/GO_0048311 mitochondrion distribution The distribution of mitochondria, including the mitochondrial genome, into daughter cells after mitosis or meiosis, mediated by interactions between mitochondria and the cytoskeleton. http://purl.obolibrary.org/obo/PR_P28329 choline O-acetyltransferase (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A choline O-acetyltransferase that is encoded in the genome of human. http://purl.obolibrary.org/obo/GO_0000011 vacuole inheritance http://purl.obolibrary.org/obo/GO_0048308 organelle inheritance The distribution of vacuoles into daughter cells after mitosis or meiosis, mediated by interactions between vacuoles and the cytoskeleton. http://purl.obolibrary.org/obo/PR_P28906 hematopoietic progenitor cell antigen CD34 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A CD34 molecule that is encoded in the genome of human. http://purl.obolibrary.org/obo/GO_0000018 regulation of DNA recombination http://purl.obolibrary.org/obo/GO_0051052 regulation of DNA metabolic process Any process that modulates the frequency, rate or extent of DNA recombination, a DNA metabolic process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. http://purl.obolibrary.org/obo/PR_P28907 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein An ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/GO_0000041 transition metal ion transport http://purl.obolibrary.org/obo/GO_0030001 metal ion transport The directed movement of transition metal ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver. http://purl.obolibrary.org/obo/PR_P29475 nitric oxide synthase 1 (human) http://purl.obolibrary.org/obo/PR_000011326 nitric oxide synthase 1 A nitric oxide synthase 1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/GO_0000048 peptidyltransferase activity http://purl.obolibrary.org/obo/GO_0140101 catalytic activity, acting on a tRNA Catalysis of the reaction: peptidyl-tRNA(1) + aminoacyl-tRNA(2) = tRNA(1) + peptidylaminoacyl-tRNA(2). This reaction is catalyzed by a ribozyme. http://purl.obolibrary.org/obo/PR_P29965 CD40 ligand (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A tumor necrosis factor ligand superfamily member 5 that is encoded in the genome of human. http://purl.obolibrary.org/obo/GO_0000049 tRNA binding http://purl.obolibrary.org/obo/GO_0003723 RNA binding Binding to a transfer RNA. http://purl.obolibrary.org/obo/PR_P30204 macrophage scavenger receptor types I and II (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A macrophage scavenger receptor types I and II that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/GO_0000070 mitotic sister chromatid segregation http://purl.obolibrary.org/obo/GO_1903047 mitotic cell cycle process The cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the mitotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner. One homolog of each morphologic type goes into each of the resulting chromosome sets. http://purl.obolibrary.org/obo/PR_P30559 oxytocin receptor (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein An oxytocin receptor that is encoded in the genome of human. http://purl.obolibrary.org/obo/GO_0000105 L-histidine biosynthetic process http://purl.obolibrary.org/obo/GO_0170038 proteinogenic amino acid biosynthetic process The chemical reactions and pathways resulting in the formation of L-histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid. http://purl.obolibrary.org/obo/PR_P31041 T-cell-specific surface glycoprotein CD28 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A T-cell-specific surface glycoprotein CD28 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/GO_0000139 Golgi membrane http://purl.obolibrary.org/obo/GO_0098588 bounding membrane of organelle The lipid bilayer surrounding any of the compartments of the Golgi apparatus. http://purl.obolibrary.org/obo/PR_P31428 dipeptidase 1 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A dipeptidase 1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/GO_0000166 nucleotide binding http://purl.obolibrary.org/obo/GO_1901363 heterocyclic compound binding Binding to a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose. http://purl.obolibrary.org/obo/PR_P31996 macrosialin (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A macrosialin that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/GO_0000226 microtubule cytoskeleton organization http://purl.obolibrary.org/obo/GO_0007017 microtubule-based process A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins. http://purl.obolibrary.org/obo/PR_P31997 cell adhesion molecule CEACAM8 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A cell adhesion molecule CEACAM8 that is encoded in the genome of human. http://purl.obolibrary.org/obo/GO_0000228 nuclear chromosome http://purl.obolibrary.org/obo/GO_0005694 chromosome A chromosome that encodes the nuclear genome and is found in the nucleus of a eukaryotic cell during the cell cycle phases when the nucleus is intact. http://purl.obolibrary.org/obo/PR_P32246 C-C chemokine receptor type 1 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A C-C chemokine receptor type 1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/GO_0000262 mitochondrial chromosome http://purl.obolibrary.org/obo/GO_0005694 chromosome A chromosome found in the mitochondrion of a eukaryotic cell. http://purl.obolibrary.org/obo/PR_P32302 C-X-C chemokine receptor type 5 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A C-X-C chemokine receptor type 5 that is encoded in the genome of human. http://purl.obolibrary.org/obo/GO_0000266 mitochondrial fission http://purl.obolibrary.org/obo/GO_0048285 organelle fission The division of a mitochondrion within a cell to form two or more separate mitochondrial compartments. http://purl.obolibrary.org/obo/PR_P32648 VIP peptides (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A VIP peptides that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/GO_0000271 polysaccharide biosynthetic process http://purl.obolibrary.org/obo/GO_0016051 carbohydrate biosynthetic process The chemical reactions and pathways resulting in the formation of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically. http://purl.obolibrary.org/obo/PR_P32848 parvalbumin alpha (mouse) http://purl.obolibrary.org/obo/PR_000013502 parvalbumin alpha A parvalbumin alpha that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/GO_0000272 polysaccharide catabolic process http://purl.obolibrary.org/obo/GO_0016052 carbohydrate catabolic process The chemical reactions and pathways resulting in the breakdown of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically. http://purl.obolibrary.org/obo/PR_P70658 C-X-C chemokine receptor type 4 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A C-X-C chemokine receptor type 4 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/GO_0000278 mitotic cell cycle http://purl.obolibrary.org/obo/GO_0007049 cell cycle Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent. http://purl.obolibrary.org/obo/PR_P70663 SPARC-like protein 1 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A SPARC-like protein 1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/GO_0000279 M phase http://purl.obolibrary.org/obo/GO_0022403 cell cycle phase A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase. http://purl.obolibrary.org/obo/PR_P78412 iroquois-class homeodomain protein IRX-6 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein An iroquois-class homeodomain protein IRX-6 that is encoded in the genome of human. http://purl.obolibrary.org/obo/GO_0000280 nuclear division http://purl.obolibrary.org/obo/GO_0048285 organelle fission The division of a cell nucleus into two nuclei, with DNA and other nuclear contents distributed between the daughter nuclei. http://purl.obolibrary.org/obo/PR_P78424 POU domain, class 6, transcription factor 2 (human) http://purl.obolibrary.org/obo/PR_000013047 POU domain, class 6, transcription factor 2 A POU domain, class 6, transcription factor 2 that is encoded in the genome of human. http://purl.obolibrary.org/obo/GO_0000295 adenine nucleotide transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0015216 purine nucleotide transmembrane transporter activity Enables the transfer of adenine nucleotides (AMP, ADP, and ATP) from one side of a membrane to the other. http://purl.obolibrary.org/obo/PR_P97367 homeobox protein Meis2 (mouse) http://purl.obolibrary.org/obo/PR_000010317 homeobox protein Meis2 A homeobox protein Meis2 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/GO_0000302 response to reactive oxygen species http://purl.obolibrary.org/obo/GO_1901700 response to oxygen-containing compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals. http://purl.obolibrary.org/obo/PR_P97449 aminopeptidase N (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein An aminopeptidase N that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/GO_0000303 response to superoxide http://purl.obolibrary.org/obo/GO_0000305 response to oxygen radical Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a superoxide stimulus. Superoxide is the anion, oxygen-, formed by addition of one electron to dioxygen (O2) or any compound containing the superoxide anion. http://purl.obolibrary.org/obo/PR_Q3UR32 P2X purinoceptor 3 (mouse) http://purl.obolibrary.org/obo/PR_000012190 P2X purinoceptor 3 A P2X purinoceptor 3 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/GO_0000305 response to oxygen radical http://purl.obolibrary.org/obo/GO_0000302 response to reactive oxygen species Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen radical stimulus. An oxygen radical is any oxygen species that carries a free electron; examples include hydroxyl radicals and the superoxide anion. http://purl.obolibrary.org/obo/PR_Q3V009 transmembrane emp24 domain-containing protein 1 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A transmembrane emp24 domain-containing protein 1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/GO_0000313 organellar ribosome http://purl.obolibrary.org/obo/GO_0005840 ribosome A ribosome contained within a subcellular membrane-bounded organelle. http://purl.obolibrary.org/obo/PR_Q3V3R4 integrin alpha-1 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein An integrin alpha-1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/GO_0000323 lytic vacuole http://purl.obolibrary.org/obo/GO_0005773 vacuole A vacuole that is maintained at an acidic pH and which contains degradative enzymes, including a wide variety of acid hydrolases. http://purl.obolibrary.org/obo/PR_Q6DYE8 ectonucleotide pyrophosphatase/phosphodiesterase family member 3 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein An ectonucleotide pyrophosphatase/phosphodiesterase family member 3 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/GO_0000578 embryonic axis specification http://purl.obolibrary.org/obo/GO_0009880 embryonic pattern specification The establishment, maintenance and elaboration of a pattern along a line or a point in an embryo. http://purl.obolibrary.org/obo/PR_Q6EIG7 C-type lectin domain family 6 member A (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A C-type lectin domain family 6 member A that is encoded in the genome of human. http://purl.obolibrary.org/obo/GO_0000740 nuclear membrane fusion http://purl.obolibrary.org/obo/GO_0071763 nuclear membrane organization The joining of 2 or more lipid bilayer membranes that surround the nucleus. http://purl.obolibrary.org/obo/PR_Q6PZD9 CCAAT/enhancer-binding protein epsilon (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A CCAAT/enhancer-binding protein epsilon that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/GO_0000741 karyogamy http://purl.obolibrary.org/obo/GO_0048284 organelle fusion The creation of a single nucleus from multiple nuclei as a result of fusing the lipid bilayers that surround each nuclei. http://purl.obolibrary.org/obo/PR_Q6QLQ4 C-type lectin domain family 7 member A (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A C-type lectin domain family 7 member A that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/GO_0000768 syncytium formation by plasma membrane fusion http://purl.obolibrary.org/obo/GO_0006949 syncytium formation The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells. http://purl.obolibrary.org/obo/PR_Q6R6I7 relaxin receptor 1 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A relaxin receptor 1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/GO_0000785 chromatin http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome. http://purl.obolibrary.org/obo/PR_Q8NFU0 bestrophin-4 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A bestrophin-4 that is encoded in the genome of human. http://purl.obolibrary.org/obo/GO_0000791 euchromatin http://purl.obolibrary.org/obo/GO_0000785 chromatin A dispersed and relatively uncompacted form of chromatin that is in a transcription-competent conformation. http://purl.obolibrary.org/obo/PR_Q9C0K0 B-cell lymphoma/leukemia 11B (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A B-cell lymphoma/leukemia 11B that is encoded in the genome of human. http://purl.obolibrary.org/obo/GO_0000792 heterochromatin http://purl.obolibrary.org/obo/GO_0000785 chromatin A compact and highly condensed form of chromatin that is refractory to transcription. http://purl.obolibrary.org/obo/PR_Q9CXI3 DBH-like monooxygenase protein 1 (mouse) http://purl.obolibrary.org/obo/PR_000010529 DBH-like monooxygenase protein 1 A DBH-like monooxygenase protein 1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/GO_0000803 sex chromosome http://purl.obolibrary.org/obo/GO_0005694 chromosome A chromosome involved in sex determination. http://purl.obolibrary.org/obo/PR_Q9CXM0 chondrolectin (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A chondrolectin that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/GO_0000819 sister chromatid segregation http://purl.obolibrary.org/obo/GO_0098813 nuclear chromosome segregation The cell cycle process in which sister chromatids are organized and then physically separated and apportioned to two or more sets. http://purl.obolibrary.org/obo/PR_Q9D387 lysosome-associated membrane glycoprotein 5 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A lysosome-associated membrane glycoprotein 5 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/GO_0000902 cell morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The developmental process in which the size or shape of a cell is generated and organized. http://purl.obolibrary.org/obo/PR_Q9QXH4 integrin alpha-X (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein An integrin alpha-X that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/GO_0000957 mitochondrial RNA catabolic process http://purl.obolibrary.org/obo/GO_0006401 RNA catabolic process The chemical reactions and pathways resulting in the breakdown of RNA transcribed from the mitochondrial genome and occurring in the mitochondrion. http://purl.obolibrary.org/obo/PR_Q9QXZ9 melanopsin (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A melanopsin that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/GO_0000959 mitochondrial RNA metabolic process http://purl.obolibrary.org/obo/GO_0016070 RNA metabolic process The chemical reactions and pathways involving RNA transcribed from the mitochondrial genome and occurring in the mitochondrion. http://purl.obolibrary.org/obo/PR_Q9QYM9 tomoregulin-2 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A tomoregulin-2 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/GO_0000960 regulation of mitochondrial RNA catabolic process http://purl.obolibrary.org/obo/GO_0009894 regulation of catabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving catabolism in the mitochondrion of RNA transcribed from the mitochondrial genome. http://purl.obolibrary.org/obo/PR_Q9R053 sodium channel protein type 11 subunit alpha (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A sodium channel protein type 11 subunit alpha that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/GO_0000961 negative regulation of mitochondrial RNA catabolic process http://purl.obolibrary.org/obo/GO_1902369 negative regulation of RNA catabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving catabolism in the mitochondrion of RNA transcribed from the mitochondrial genome. http://purl.obolibrary.org/obo/PR_Q9R1R0 LIM/homeobox protein Lhx6 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A LIM/homeobox protein Lhx6 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/GO_0000962 positive regulation of mitochondrial RNA catabolic process http://purl.obolibrary.org/obo/GO_0009896 positive regulation of catabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving catabolism in the mitochondrion of RNA transcribed from the mitochondrial genome. http://purl.obolibrary.org/obo/PR_Q9R1W5 calcitonin gene-related peptide type 1 receptor (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A calcitonin gene-related peptide type 1 receptor that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/GO_0001101 response to acid chemical http://purl.obolibrary.org/obo/GO_0042221 response to chemical Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by the chemical structure of the anion portion of a dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form. http://purl.obolibrary.org/obo/UBERON_0035431 mediastinal pleura http://purl.obolibrary.org/obo/UBERON_0034944 zone of organ The parietal pleura that lines the mediastinum. http://purl.obolibrary.org/obo/GO_0001501 skeletal system development http://purl.obolibrary.org/obo/GO_0048731 system development The process whose specific outcome is the progression of the skeleton over time, from its formation to the mature structure. The skeleton is the bony framework of the body in vertebrates (endoskeleton) or the hard outer envelope of insects (exoskeleton or dermoskeleton). http://purl.obolibrary.org/obo/UBERON_0035819 abdominopelvic cavity http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space The part of the ventral body cavity that is within the abdominal segment of the trunk, which encompasses the abdomen proper plus pelvic cavity. http://purl.obolibrary.org/obo/GO_0001503 ossification http://purl.obolibrary.org/obo/GO_0032501 multicellular organismal process The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance. http://purl.obolibrary.org/obo/UBERON_0035109 plantar nerve http://purl.obolibrary.org/obo/UBERON_0003431 leg nerve A nerve that innervates the sole of the foot. Planar nerves arise from the posterior branch of the tibial nerve. http://purl.obolibrary.org/obo/GO_0001504 neurotransmitter uptake http://purl.obolibrary.org/obo/GO_0098657 import into cell The directed movement of neurotransmitters into neurons or glial cells. This process leads to inactivation and recycling of neurotransmitters. http://purl.obolibrary.org/obo/GO_0001507 acetylcholine catabolic process in synaptic cleft http://purl.obolibrary.org/obo/GO_0006581 acetylcholine catabolic process The chemical reactions and pathways resulting in the breakdown of acetylcholine that occurs in the synaptic cleft during synaptic transmission. http://purl.obolibrary.org/obo/UBERON_0035770 inferior mesenteric nerve plexus http://purl.obolibrary.org/obo/UBERON_0000122 neuron projection bundle The inferior mesenteric plexus is derived chiefly from the aortic plexus. It surrounds the inferior mesenteric artery, and divides into a number of secondary plexuses, which are distributed to all the parts supplied by the artery, viz. , the left colic and sigmoid plexuses, which supply the descending and sigmoid parts of the colon; and the superior hemorrhoidal plexus, which supplies the rectum and joins in the pelvis with branches from the pelvic plexuses. http://purl.obolibrary.org/obo/GO_0001508 action potential http://purl.obolibrary.org/obo/GO_0042391 regulation of membrane potential A process in which membrane potential cycles through a depolarizing spike, triggered in response to depolarization above some threshold, followed by repolarization. This cycle is driven by the flow of ions through various voltage gated channels with different thresholds and ion specificities. http://purl.obolibrary.org/obo/UBERON_0035784 seminal clot http://purl.obolibrary.org/obo/UBERON_0001968 semen A portion of semen in a coagulated state. http://purl.obolibrary.org/obo/GO_0001518 voltage-gated sodium channel complex http://purl.obolibrary.org/obo/GO_0098797 plasma membrane protein complex A sodium channel in a cell membrane whose opening is governed by the membrane potential. http://purl.obolibrary.org/obo/GO_0140013 meiotic nuclear division http://purl.obolibrary.org/obo/GO_1903046 meiotic cell cycle process One of the two nuclear divisions that occur as part of the meiotic cell cycle. http://purl.obolibrary.org/obo/GO_0001525 angiogenesis http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels. http://purl.obolibrary.org/obo/GO_0140056 organelle localization by membrane tethering http://purl.obolibrary.org/obo/GO_0051640 organelle localization The process by which an organelle membrane interacts with another membrane via molecular tethers that physically bridge the two membranes and attach them to each other. http://purl.obolibrary.org/obo/GO_0001534 radial spoke http://purl.obolibrary.org/obo/GO_0032991 protein-containing complex Protein complex that links the outer microtubule doublet of a 9+2 type ciliary or flagellar axoneme with the sheath that surrounds the central pair of microtubules. Composed of a stalk that attaches to each doublet microtubule and a globular structure (spoke head) that projects toward the central pair of microtubules. http://purl.obolibrary.org/obo/GO_0150063 visual system development http://purl.obolibrary.org/obo/GO_0048880 sensory system development The process whose specific outcome is the progression of the visual system over time, from its formation to the mature structure, including the eye, parts of the central nervous system (CNS) involved in processing of visual inputs, and connecting nerve pathways. http://purl.obolibrary.org/obo/GO_0001539 cilium or flagellum-dependent cell motility http://purl.obolibrary.org/obo/GO_0048870 cell motility Cell motility due to movement of eukaryotic cilia or bacterial-type flagella or archaeal-type flagella. http://purl.obolibrary.org/obo/UBERON_4300226 forelimb bud mesenchyme http://purl.obolibrary.org/obo/UBERON_0010328 limb bud mesenchyme Mesenchyme that is part of a forelimb bud. http://purl.obolibrary.org/obo/GO_0001541 ovarian follicle development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the ovarian follicle over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/UBERON_4300227 hindlimb bud mesenchyme http://purl.obolibrary.org/obo/UBERON_0010328 limb bud mesenchyme Mesenchyme that is part of a hindlimb bud. http://purl.obolibrary.org/obo/GO_0001545 primary ovarian follicle growth http://purl.obolibrary.org/obo/GO_0048589 developmental growth Increase in size of primary follicles including oocyte growth and granulosa and/or theca cell proliferation until more than one layer of granulosa cells is present (preantral follicle). http://purl.obolibrary.org/obo/GO_0110122 myotube cell migration http://purl.obolibrary.org/obo/GO_0014812 muscle cell migration The orderly movement of a myotube cell from one site to another, often during the development of a multicellular organism. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate, and fuse. http://purl.obolibrary.org/obo/GO_0001546 preantral ovarian follicle growth http://purl.obolibrary.org/obo/GO_0048589 developmental growth Increase in size of follicles surrounded by two or more layers of granulosa cells up to the onset of antrum formation. http://purl.obolibrary.org/obo/GO_0110123 regulation of myotube cell migration http://purl.obolibrary.org/obo/GO_0030334 regulation of cell migration Any process that modulates the frequency, rate or extent of myotube cell migration. http://purl.obolibrary.org/obo/GO_0001547 antral ovarian follicle growth http://purl.obolibrary.org/obo/GO_0048589 developmental growth Increase in size of antral follicles due to cell proliferation and/or growth of the antral cavity. http://purl.obolibrary.org/obo/GO_0001549 cumulus cell differentiation http://purl.obolibrary.org/obo/GO_0060014 granulosa cell differentiation The process in which a subpopulation of granulosa cells surrounding the oocyte acquires the specialized features of an ovarian cumulus cell. http://purl.obolibrary.org/obo/GO_0110124 positive regulation of myotube cell migration http://purl.obolibrary.org/obo/GO_0030335 positive regulation of cell migration Any process that activates, maintains or increases the frequency, rate or extent of myotube cell migration. http://purl.obolibrary.org/obo/GO_0001552 ovarian follicle atresia http://purl.obolibrary.org/obo/GO_0003006 developmental process involved in reproduction A periodic process in which immature ovarian follicles degenerate and are subsequently re-absorbed. http://purl.obolibrary.org/obo/GO_0110125 negative regulation of myotube cell migration http://purl.obolibrary.org/obo/GO_0030336 negative regulation of cell migration Any process that stops, prevents, or reduces the frequency, rate or extent of myotube cell migration. http://purl.obolibrary.org/obo/GO_0001553 luteinization http://purl.obolibrary.org/obo/GO_0022602 ovulation cycle process The set of processes resulting in differentiation of theca and granulosa cells into luteal cells and in the formation of a corpus luteum after ovulation. http://purl.obolibrary.org/obo/GO_0120193 tight junction organization http://purl.obolibrary.org/obo/GO_0045216 cell-cell junction organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a tight junction. A tight junction seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other. http://purl.obolibrary.org/obo/GO_0001555 oocyte growth http://purl.obolibrary.org/obo/GO_0048588 developmental cell growth The developmental growth process in which an oocyte irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present. http://purl.obolibrary.org/obo/CL_0011025 exhausted T cell http://purl.obolibrary.org/obo/CL_0000911 effector T cell An effector T cell that displays impaired effector functions (e.g., rapid production of effector cytokines, cytotoxicity) and has limited proliferative potential. http://purl.obolibrary.org/obo/GO_0001556 oocyte maturation http://purl.obolibrary.org/obo/GO_0048469 cell maturation A developmental process, independent of morphogenetic (shape) change, that is required for an oocyte to attain its fully functional state. Oocyte maturation commences after reinitiation of meiosis commonly starting with germinal vesicle breakdown, and continues up to the second meiotic arrest prior to fertilization. http://purl.obolibrary.org/obo/PATO_0070017 standard pyramidal morphology http://purl.obolibrary.org/obo/PATO_0070015 pyramidal family morphology A pyramidal family morphology that inheres in neurons which have a standard pyramidal shape with its apical dendrite aligned vertically. http://purl.obolibrary.org/obo/GO_0001558 regulation of cell growth http://purl.obolibrary.org/obo/GO_0051128 regulation of cellular component organization Any process that modulates the frequency, rate, extent or direction of cell growth. http://purl.obolibrary.org/obo/PATO_0070016 horizontal pyramidal morphology http://purl.obolibrary.org/obo/PATO_0070015 pyramidal family morphology A pyramidal family morphology that inheres in neurons which have an apical tree which is oriented parallel to the pia. http://purl.obolibrary.org/obo/GO_0001560 regulation of cell growth by extracellular stimulus http://purl.obolibrary.org/obo/GO_0001558 regulation of cell growth Any process in which external signals modulate the frequency, rate or extent of cell growth, the irreversible increase in size of a cell over time. http://purl.obolibrary.org/obo/PATO_0070011 chandelier cell morphology http://purl.obolibrary.org/obo/PATO_0010006 cell morphology A cell morphology that inheres in neurons which are small and round, and make highly specialized synapses with the axon initial segments of pyramidal neurons, wrapping them with candle-shaped synaptic 'cartridges'. http://purl.obolibrary.org/obo/GO_0001568 blood vessel development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of a blood vessel over time, from its formation to the mature structure. The blood vessel is the vasculature carrying blood. http://purl.obolibrary.org/obo/GO_0001569 branching involved in blood vessel morphogenesis http://purl.obolibrary.org/obo/GO_0048754 branching morphogenesis of an epithelial tube The process of coordinated growth and sprouting of blood vessels giving rise to the organized vascular system. http://purl.obolibrary.org/obo/PATO_0070007 Martinotti morphology http://purl.obolibrary.org/obo/PATO_0070026 multipolar neuron morphology A cell morphology that inheres in neurons which are large and non-spiny, with dendrites radiating in a multipolar or bitufted pattern, often favouring the descending side, and axons that ascend directly from the superficial side of the soma, and travel upward without branching. http://purl.obolibrary.org/obo/GO_0001570 vasculogenesis http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The differentiation of endothelial cells from progenitor cells during blood vessel development, and the de novo formation of blood vessels and tubes. http://purl.obolibrary.org/obo/CL_4023045 medulla-projecting glutamatergic neuron of the primary motor cortex http://purl.obolibrary.org/obo/CL_2000049 primary motor cortex pyramidal cell An extratelencephalic-projecting glutamatergic neuron located in layer 5b of the primary motor cortex that projects to the medulla. MY ET cells are large, big-tufted cells with the apical dendrite often bifurcating close to the soma, suggesting they are corticospinal cells. MY ET cells have bigger hyperpolarization sag, lower input resistance, and smaller AP width, compared to L5 IT neurons. http://purl.obolibrary.org/obo/GO_0001578 microtubule bundle formation http://purl.obolibrary.org/obo/GO_0000226 microtubule cytoskeleton organization A process that results in a parallel arrangement of microtubules. http://purl.obolibrary.org/obo/GO_0140734 ammonium excretion http://purl.obolibrary.org/obo/GO_0007588 excretion The elimination of ammonium ions from an excretory cell. http://purl.obolibrary.org/obo/GO_0001614 purinergic nucleotide receptor activity http://purl.obolibrary.org/obo/GO_0016502 nucleotide receptor activity Combining with a purine nucleotide and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. http://purl.obolibrary.org/obo/CL_4030006 fallopian tube secretory epithelial cell http://purl.obolibrary.org/obo/CL_1001591 oviduct secretory cell An epithelial cell that is part of the fallopian tube that secretes mucus and oviduct-specific products in response to hormonal stimulation from estrogen and luteinizing hormone. This fallopian tube secretory cell is similar in height to the ciliated cell, but typically exhibits a more narrow, columnar shape. Its nucleus is ovoid and oriented perpendicular to the cell's long axis, with denser chromatin and a smaller nucleolus compared to the ciliated cell. http://purl.obolibrary.org/obo/GO_0001621 G protein-coupled ADP receptor activity http://purl.obolibrary.org/obo/GO_0045028 G protein-coupled purinergic nucleotide receptor activity Combining with ADP and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. http://purl.obolibrary.org/obo/UBERON_8410080 red bone marrow of sternum http://purl.obolibrary.org/obo/UBERON_0000361 red bone marrow Red bone marrow located in the sternum. http://purl.obolibrary.org/obo/GO_0001649 osteoblast differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process whereby a relatively unspecialized cell acquires the specialized features of an osteoblast, a mesodermal or neural crest cell that gives rise to bone. http://purl.obolibrary.org/obo/UBERON_8440015 noradrenergic cell groups http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain Collections of neurons in the central nervous system that have been demonstrated by histochemical fluorescence to contain the neurotransmitter norepinephrine (noradrenalin). http://purl.obolibrary.org/obo/GO_0001653 peptide receptor activity http://purl.obolibrary.org/obo/GO_0038023 signaling receptor activity Combining with an extracellular or intracellular peptide to initiate a change in cell activity. http://purl.obolibrary.org/obo/UBERON_8470001 sublumbar lymph node http://purl.obolibrary.org/obo/UBERON_0000029 lymph node A lymph node with a lymph center located within the caudal abdomen and pelvis, on the ventral side of the lumbar region. Includes the medial iliac, internal iliac (previously termed hypogastric) and sacral lymph nodes. http://purl.obolibrary.org/obo/GO_0001654 eye development http://purl.obolibrary.org/obo/GO_0007423 sensory organ development The process whose specific outcome is the progression of the eye over time, from its formation to the mature structure. The eye is the organ of sight. http://purl.obolibrary.org/obo/CL_0003041 M9-ON retinal ganglion cell http://purl.obolibrary.org/obo/CL_4023032 ON retinal ganglion cell An M9 retinal ganglion cells with synaptic terminals in S2 and is depolarized by illumination of its receptive field center. http://purl.obolibrary.org/obo/GO_0001655 urogenital system development http://purl.obolibrary.org/obo/GO_0048731 system development The process whose specific outcome is the progression of the urogenital system over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/CL_0003030 M3 retinal ganglion cell http://purl.obolibrary.org/obo/CL_0000740 retinal ganglion cell A monostratified retinal ganglion cell that has a medium soma and a small dendrite field. http://purl.obolibrary.org/obo/GO_0001656 metanephros development http://purl.obolibrary.org/obo/GO_0001822 kidney development The process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. In mammals, the metanephros is the excretory organ of the fetus, which develops into the mature kidney and is formed from the rear portion of the nephrogenic cord. The metanephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine. http://purl.obolibrary.org/obo/CL_0003029 M2 retinal ganglion cell http://purl.obolibrary.org/obo/CL_0000740 retinal ganglion cell A monostratified retinal ganglion cell that has a small soma, a small dendrite field with a dense dendrite arbor, and post synaptic terminals in sublaminer layer S2 and S3. http://purl.obolibrary.org/obo/GO_0001657 ureteric bud development http://purl.obolibrary.org/obo/GO_0072164 mesonephric tubule development The process whose specific outcome is the progression of the ureteric bud over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/CL_0004240 WF1 amacrine cell http://purl.obolibrary.org/obo/CL_0004253 wide field retinal amacrine cell An amacrine cell with a wide dendritic field, dendrites in S1, and post-synaptic terminals in S1. http://purl.obolibrary.org/obo/GO_0001658 branching involved in ureteric bud morphogenesis http://purl.obolibrary.org/obo/GO_0048754 branching morphogenesis of an epithelial tube The process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules. http://purl.obolibrary.org/obo/CL_0003021 retinal ganglion cell C4 http://purl.obolibrary.org/obo/CL_0003020 retinal ganglion cell C outer A retinal ganglion cell C outer that has a medium dendritic field and a dense dendritic arbor. http://purl.obolibrary.org/obo/GO_0001659 temperature homeostasis http://purl.obolibrary.org/obo/GO_0048871 multicellular organismal-level homeostasis A homeostatic process in which an organism modulates its internal body temperature. http://purl.obolibrary.org/obo/CL_0003017 retinal ganglion cell B3 outer http://purl.obolibrary.org/obo/CL_0004183 retinal ganglion cell B3 A retinal ganglion B cell that has post synaptic terminals in S2. http://purl.obolibrary.org/obo/GO_0001664 G protein-coupled receptor binding http://purl.obolibrary.org/obo/GO_0005102 signaling receptor binding Binding to a G protein-coupled receptor. http://purl.obolibrary.org/obo/CL_4023035 lateral ganglionic eminence derived neuron http://purl.obolibrary.org/obo/CL_2000029 central nervous system neuron A neuron that is derived from a precursor cell in the lateral ganglion eminence. http://purl.obolibrary.org/obo/GO_0001666 response to hypoxia http://purl.obolibrary.org/obo/GO_0036293 response to decreased oxygen levels Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level. http://purl.obolibrary.org/obo/CL_4033062 interstitial extravillous trophoblast cell http://purl.obolibrary.org/obo/CL_0000351 trophoblast cell A trophoblast cell that invades the uterine wall to anchor the placenta to the uterus. An interstitial extravillous trophoblast cell differentiates from an extravillous trophoblast cell, becoming hyperchromatic and changing its morphology to a fibroblast-like spindle-shaped cell. In humans, this cell can be distinguished by the expression of placental-specific protein 8, which stimulates migration. http://purl.obolibrary.org/obo/GO_0001667 ameboidal-type cell migration http://purl.obolibrary.org/obo/GO_0016477 cell migration Cell migration that is accomplished by extension and retraction of a pseudopodium. http://purl.obolibrary.org/obo/CL_4033063 endovascular extravillous trophoblast cell http://purl.obolibrary.org/obo/CL_0000351 trophoblast cell A trophoblast cell that invades the maternal spiral arteries and replace the endothelial lining, remodeling the vessels and allowing for adequate blood transport into the placenta. An endovascular extravillous trophoblast cell differentiates from an extravillous trophoblast cell. In humans, this cell can be distinguished by the expression of CD56. http://purl.obolibrary.org/obo/GO_0001669 acrosomal vesicle http://purl.obolibrary.org/obo/GO_0030141 secretory granule A structure in the head of a spermatozoon that contains acid hydrolases, and is concerned with the breakdown of the outer membrane of the ovum during fertilization. It lies just beneath the plasma membrane and is derived from the lysosome. http://purl.obolibrary.org/obo/CL_4033064 uterine resident macrophage http://purl.obolibrary.org/obo/CL_0000864 tissue-resident macrophage A tissue-resident macrophage that is part of the uterus. http://purl.obolibrary.org/obo/GO_0001673 male germ cell nucleus http://purl.obolibrary.org/obo/GO_0043073 germ cell nucleus The nucleus of a male germ cell, a reproductive cell in males. http://purl.obolibrary.org/obo/GO_0141187 nucleic acid biosynthetic process http://purl.obolibrary.org/obo/GO_0034654 nucleobase-containing compound biosynthetic process The biosynthetic process resulting in the formation of a nucleic acid. http://purl.obolibrary.org/obo/GO_0001674 female germ cell nucleus http://purl.obolibrary.org/obo/GO_0043073 germ cell nucleus The nucleus of the female germ cell, a reproductive cell in females. http://purl.obolibrary.org/obo/GO_0160173 histamine transmembrane transporter activity http://purl.obolibrary.org/obo/GO_1901474 azole transmembrane transporter activity Enables the transfer of histamine from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0001675 acrosome assembly http://purl.obolibrary.org/obo/GO_0070925 organelle assembly The formation of the acrosome from the spermatid Golgi. http://purl.obolibrary.org/obo/CL_4033083 squamous granulosa cell http://purl.obolibrary.org/obo/CL_0000501 granulosa cell A granulosa cell that has a squamous morphology and form a single layer around the oocyte in primordial follicles. This cell develops directly into a cuboidal granulosa cell during the primordial-to-primary follicle transition. http://purl.obolibrary.org/obo/GO_0001677 formation of translation initiation ternary complex http://purl.obolibrary.org/obo/GO_0022618 protein-RNA complex assembly Formation of a complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2 (either eIF2 in eukaryotes, or IF2 in prokaryotes). In prokaryotes, fMet-tRNA (initiator) is used rather than Met-tRNA (initiator). http://purl.obolibrary.org/obo/CL_4033084 cuboidal granulosa cell http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure A granulosa cell that has a cuboidal morphology and develops from squamous granulosa cell during the transition between primordial follicle to primary follicle. Cuboidal granulosa cells proliferate to form a second layer within secondary follicles. http://purl.obolibrary.org/obo/GO_0001678 intracellular glucose homeostasis http://purl.obolibrary.org/obo/GO_0055082 intracellular chemical homeostasis A homeostatic process involved in the maintenance of a steady state level of glucose within a cell. http://purl.obolibrary.org/obo/CL_4042017 alpha1-tanycyte http://purl.obolibrary.org/obo/CL_0002085 tanycyte The dorsal-most tanycyte type of the third venticle. These cells projects into the ventromedial or dorsomedial nucleus of the hypothalamus. This type of tanycyte extends its protrusions close to parenchymal neurons without contacting blood vessels. It expresses the glial marker S-100β. http://purl.obolibrary.org/obo/GO_0001692 histamine metabolic process http://purl.obolibrary.org/obo/GO_0052803 imidazole-containing compound metabolic process The chemical reactions and pathways involving histamine, a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans. http://purl.obolibrary.org/obo/CL_4042018 alpha2-tanycyte http://purl.obolibrary.org/obo/CL_0002085 tanycyte Tanycyte of the third ventricle, located immediately ventral to alpha-1 tanycytes. These cells project to the ventromedial and arcuate nuclei of the hypothalamus and express the glial marker S-100β. http://purl.obolibrary.org/obo/GO_0001694 histamine biosynthetic process http://purl.obolibrary.org/obo/GO_0042401 biogenic amine biosynthetic process The chemical reactions and pathways resulting in the formation of histamine, a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans. http://purl.obolibrary.org/obo/CL_4042019 beta1-tanycyte http://purl.obolibrary.org/obo/CL_0002085 tanycyte A type of tanycyte located in ventral part of the lateral wall of the third ventricle and in the lateral infundibular recess of the brain. This tanycyte has an elongated morphology with multiple microvilli extending into the median eminence. This type of tanycyte expresses FGF receptors 1 and 2, is in contact with GnRH neurons, and is involved in the release of gonadotropin-releasing hormone (GnRH). http://purl.obolibrary.org/obo/GO_0001695 histamine catabolic process http://purl.obolibrary.org/obo/GO_0052805 imidazole-containing compound catabolic process The chemical reactions and pathways resulting in the breakdown of histamine, a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans. http://purl.obolibrary.org/obo/CL_4042020 beta2-tanycyte http://purl.obolibrary.org/obo/CL_0002085 tanycyte A type of tanycyte located in the floor of third ventricle and the infindibular recess. This tanycyte has an elongated morphology with multiple microvilli extending medially and ventrally to the median eminence, contacting the pial surface and blood vessels. This type of tanycyte expresses FGF receptors 1 and 2, is in contact with GnRH neurons, and is involved in the release of gonadotropin-releasing hormone (GnRH). http://purl.obolibrary.org/obo/GO_0001696 gastric acid secretion http://purl.obolibrary.org/obo/GO_0046717 acid secretion The regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion. http://purl.obolibrary.org/obo/CL_4042021 neuronal-restricted precursor http://purl.obolibrary.org/obo/CL_0011026 progenitor cell A progenitor cell of the central nervous system that differentiates exclusively onto neurons. This progenitor cell is found in a hippocampus subventricular zone, developing cortex and spinal cord of the central nervous system. http://purl.obolibrary.org/obo/GO_0001700 embryonic development via the syncytial blastoderm http://purl.obolibrary.org/obo/GO_0009792 embryo development ending in birth or egg hatching The process whose specific outcome is the progression of the embryo over time, from zygote formation through syncytial blastoderm to the hatching of the first instar larva. An example of this process is found in Drosophila melanogaster. http://purl.obolibrary.org/obo/CL_4042022 astrocyte-restricted precursor http://purl.obolibrary.org/obo/CL_0011026 progenitor cell A progenitor cell of the central nervous system that differentiates exclusively onto astrocytes. This progenitor cell expresses CD44 and S100 calcium-binding protein B. http://purl.obolibrary.org/obo/GO_0001701 in utero embryonic development http://purl.obolibrary.org/obo/GO_0043009 chordate embryonic development The process whose specific outcome is the progression of the embryo in the uterus over time, from formation of the zygote in the oviduct, to birth. An example of this process is found in Mus musculus. http://purl.obolibrary.org/obo/CL_4042023 striatal pthlh-expressing interneuron http://purl.obolibrary.org/obo/CL_0011005 GABAergic interneuron A GABAergic interneuron expressing PTHLH and PVALB that has its soma in a striatum. This GABAergic interneuron type presents a spatial expression gradient of PVALB in the mouse striatum. http://purl.obolibrary.org/obo/GO_0001702 gastrulation with mouth forming second http://purl.obolibrary.org/obo/GO_0007369 gastrulation A gastrulation process in which the initial invagination becomes the anus and the mouth forms second. http://purl.obolibrary.org/obo/CL_4042024 striatal PTHLH MOXD1 expressing interneuron http://purl.obolibrary.org/obo/CL_4042023 striatal pthlh-expressing interneuron A pthlh-expressing interneuron that expresses MOXD1 and has its soma in a striatum. http://purl.obolibrary.org/obo/GO_0001703 gastrulation with mouth forming first http://purl.obolibrary.org/obo/GO_0007369 gastrulation A gastrulation process in which the initial invagination becomes the mouth and the anus forms second. http://purl.obolibrary.org/obo/CL_4042025 substantia nigra dopaminergic neuron http://purl.obolibrary.org/obo/CL_2000097 midbrain dopaminergic neuron A midbrain dopaminergic neuron that has its soma located in a substantia nigra. This dopaminergic neuron type is highly metabolically active and it is involved in the regulation of movement, cognition, motivation and reward. Neurodegeneration of this dopaminergic neuronal type causes loss in fine motor control in Parkinson's Disease. http://purl.obolibrary.org/obo/GO_0001704 formation of primary germ layer http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The formation of the ectoderm, mesoderm and endoderm during gastrulation. http://purl.obolibrary.org/obo/CL_4042026 GABAergic interneuron of the anterior substantia nigra pars reticulata http://purl.obolibrary.org/obo/CL_0002614 neuron of the substantia nigra A GABAergic interneuron that has its soma in the anterior section of the substantia nigra pars reticulata. This GABAergic interneuron is characterized by the expression of Six3 and Foxp1 and it develops from Nkx6-2 expressing neuronal progenitors in the ventrolateral midbrain-diencephalon region. http://purl.obolibrary.org/obo/GO_0001705 ectoderm formation http://purl.obolibrary.org/obo/GO_0001704 formation of primary germ layer The formation of ectoderm during gastrulation. http://purl.obolibrary.org/obo/CL_4042027 GABAergic interneuron of the posterior substantia nigra pars reticulata http://purl.obolibrary.org/obo/CL_0002614 neuron of the substantia nigra A GABAergic interneuron that has its soma in the posterior section of the substantia nigra pars reticulata. This GABAergic interneuron is characterised by the expression of the transcription factors Pax5, Ctip2 and Pou6f2 and it develops from the ventrolateral r1 neuroepithelium expresing NKX61. http://purl.obolibrary.org/obo/GO_0001706 endoderm formation http://purl.obolibrary.org/obo/GO_0001704 formation of primary germ layer The formation of the endoderm during gastrulation. http://purl.obolibrary.org/obo/CL_4047006 fetal artery endothelial cell http://purl.obolibrary.org/obo/CL_1000413 endothelial cell of artery An endothelial cell that lines an artery in the fetal circulatory system. http://purl.obolibrary.org/obo/GO_0001707 mesoderm formation http://purl.obolibrary.org/obo/GO_0001704 formation of primary germ layer The process that gives rise to the mesoderm. This process pertains to the initial formation of the structure from unspecified parts. http://purl.obolibrary.org/obo/CL_4047007 immature pericyte http://purl.obolibrary.org/obo/CL_0000669 pericyte A pericyte that is in an early stage of development, found in newly forming or remodeling blood vessels. An immature pericyte is characterized by it's mesenchymal stem cell-like properties and high proliferative capacity, which allows it to differentiate into various types of pericytes and contribute to the structural and functional maturation of the vasculature. Immature pericytes are stellate in new vessels and elongated with less protrusions in remodeling vessels. http://purl.obolibrary.org/obo/GO_0001739 sex chromatin http://purl.obolibrary.org/obo/GO_0000792 heterochromatin Chromatin that is part of a sex chromosome. http://purl.obolibrary.org/obo/CL_4047011 fetal vein endothelial cell http://purl.obolibrary.org/obo/CL_0002543 vein endothelial cell An endothelial cell that lines the veins in the fetal circulatory system. http://purl.obolibrary.org/obo/GO_0001742 oenocyte differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of an oenocyte. Oenocytes are large secretory cells found in clusters underlying the epidermis of larval abdominal segments. http://purl.obolibrary.org/obo/CL_4047012 angiogenic pericyte http://purl.obolibrary.org/obo/CL_0000669 pericyte A specialized pericyte that actively participates in the formation of new blood vessels during angiogenesis by undergoing phenotypic changes, increasing proliferation, and interacting closely with endothelial cells. http://purl.obolibrary.org/obo/GO_0001743 lens placode formation http://purl.obolibrary.org/obo/GO_0060788 ectodermal placode formation The initial developmental process that will lead to the formation of an eye. http://purl.obolibrary.org/obo/CL_4047018 early colonocyte http://purl.obolibrary.org/obo/CL_1000347 colonocyte An enterocyte that is part of the colon, in the early stages of differentiation, located in the intestinal crypt-villus axis. http://purl.obolibrary.org/obo/GO_0001745 compound eye morphogenesis http://purl.obolibrary.org/obo/GO_0048592 eye morphogenesis The morphogenetic process in which the anatomical structures of the compound eye are generated and organized. The adult compound eye is a precise assembly of 700-800 ommatidia. Each ommatidium is composed of 20 cells, identified by cell type and position. An example of compound eye morphogenesis is found in Drosophila melanogaster. http://purl.obolibrary.org/obo/CL_4047019 early enterocyte http://purl.obolibrary.org/obo/CL_0000584 enterocyte An enterocyte in the early stages of development, located above the transit-amplifying cell zone in the intestinal crypt-villus axis. http://purl.obolibrary.org/obo/GO_0001751 compound eye photoreceptor cell differentiation http://purl.obolibrary.org/obo/GO_0001754 eye photoreceptor cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of an eye photoreceptor cell. http://purl.obolibrary.org/obo/CL_4047051 small intestine BEST4+ enterocyte http://purl.obolibrary.org/obo/CL_4030026 BEST4+ enterocyte An enterocyte of the human small intestine expressing bestrophin-4 (BEST4) calcium-activated ion channels. These enterocytes have a disinctive transcriptomic profile and are scattered through the small intestine epithelium. http://purl.obolibrary.org/obo/GO_0001754 eye photoreceptor cell differentiation http://purl.obolibrary.org/obo/GO_0046530 photoreceptor cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a photoreceptor cell, as found in the eye, the primary visual organ of most organisms. http://purl.obolibrary.org/obo/CL_4047052 BEST4+ colonocyte http://purl.obolibrary.org/obo/CL_4030026 BEST4+ enterocyte An enterocyte of the human colon expressing bestrophin-4 (BEST4) calcium-activated ion channels. These cells have a distinct transcriptomic profile compared to other enterocytes and are scattered through the colon epithelium. http://purl.obolibrary.org/obo/GO_0001755 neural crest cell migration http://purl.obolibrary.org/obo/GO_0090497 mesenchymal cell migration The characteristic movement of cells from the dorsal ridge of the neural tube to a variety of locations in a vertebrate embryo. http://purl.obolibrary.org/obo/CL_4052001 multiciliated ependymal cell http://purl.obolibrary.org/obo/CL_0005012 multiciliated epithelial cell An ependymal cell that lines the lateral, third, and fourth ventricles of the brain. The cell is characterized by multiple motile cilia on its apical surface, which beats in a coordinated manner to facilitate the movement of cerebrospinal fluid (CSF), contributing to brain homeostasis. http://purl.obolibrary.org/obo/GO_0001756 somitogenesis http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The formation of mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo. http://purl.obolibrary.org/obo/CL_4052002 syncytial cell http://purl.obolibrary.org/obo/CL_0000228 multinucleate cell A multinucleate cell formed by the fusion of multiple uninuclear cells through plasma membrane fusion. This process leads to a single large cell containing multiple nuclei within a shared cytoplasm. http://purl.obolibrary.org/obo/GO_0001763 morphogenesis of a branching structure http://purl.obolibrary.org/obo/GO_0032501 multicellular organismal process The process in which the anatomical structures of branches are generated and organized. A branch is a division or offshoot from a main stem. Examples in animals would include blood vessels, nerves, lymphatics and other endothelial or epithelial tubes. http://purl.obolibrary.org/obo/CL_4052003 intestinal villus capillary endothelial cell http://purl.obolibrary.org/obo/CL_0002144 capillary endothelial cell A capillary endothelial cell that is part of the intestinal villus. This cell is highly fenestrated, with fenestrations most numerous at the villus tips, and plays a vital role in nutrient absorption and maintaining the selective permeability of the intestinal barrier. http://purl.obolibrary.org/obo/GO_0001764 neuron migration http://purl.obolibrary.org/obo/GO_0016477 cell migration The characteristic movement of an immature neuron from germinal zones to specific positions where they will reside as they mature. http://purl.obolibrary.org/obo/CL_4052004 intestinal fibroblastic reticular cell http://purl.obolibrary.org/obo/CL_0009101 fibroblastic reticular cell A specialized fibroblastic reticular cell that is part of gut-associated lymphoid tissue (GALT), responsible for forming a structural network that facilitates immune cell interactions. This cell is found in Peyer's patches, cryptopatches, and isolated lymphoid follicles. It plays crucial roles in maintaining intestinal immunity by controlling innate lymphoid cell homeostasis and function, organizing lymphoid structures, and contributing to intestinal microbiome balance. http://purl.obolibrary.org/obo/GO_0001767 establishment of lymphocyte polarity http://purl.obolibrary.org/obo/GO_0030010 establishment of cell polarity The directed orientation of lymphocyte signaling molecules and associated membrane rafts towards a chemokine gradient or a contact point with an appropriate activating cell. http://purl.obolibrary.org/obo/CL_4052005 intestinal subserosal fibroblast http://purl.obolibrary.org/obo/CL_0000057 fibroblast A fibroblast that is part of the subserosa of intestine. This cell interacts with immune cells and play roles in inflammation and fibrosis. In certain conditions, such as Crohn's disease, subserosal fibroblast may differentiate into myofibroblasts. http://purl.obolibrary.org/obo/GO_0001768 establishment of T cell polarity http://purl.obolibrary.org/obo/GO_0001767 establishment of lymphocyte polarity The directed orientation of T cell signaling molecules and associated membrane rafts towards a chemokine gradient or a contact point with antigen presenting cell. http://purl.obolibrary.org/obo/CL_4052006 intestinal enteroendocrine progenitor http://purl.obolibrary.org/obo/CL_0011026 progenitor cell An epithelial cell that is part of the crypt of Lieberkuhn, originating from intestinal stem cells and giving rise to enteroendocrine cells (EECs). In mouse and human, this cell can be characterized by the expression of Neurog3, and has the ability to proliferate and differentiate into multiple EEC subtypes. Its proliferative potential contributes to crypt growth, distinguishing it from fully differentiated EECs. http://purl.obolibrary.org/obo/GO_0001769 establishment of B cell polarity http://purl.obolibrary.org/obo/GO_0001767 establishment of lymphocyte polarity The directed orientation of B cell signaling molecules and associated membrane rafts towards a chemokine gradient of a contact point with an antigen displaying cell. http://purl.obolibrary.org/obo/CL_4052007 subepithelial intestinal fibroblast http://purl.obolibrary.org/obo/CL_0000057 fibroblast A fibroblast located adjacent to the intestinal epithelium in both the small intestine and colon, specifically around the crypts. This cell is characterized by the expression of PDGFRα and various collagen isoforms, including COL4A5 and COL4A6. It secretes signalling molecules like TGF-β, Wnt ligands, and BMPs, which are crucial for epithelial homeostasis, intestinal stem cell support, and basement membrane formation. http://purl.obolibrary.org/obo/GO_0001770 establishment of natural killer cell polarity http://purl.obolibrary.org/obo/GO_0001767 establishment of lymphocyte polarity The directed orientation of natural killer cell signaling molecules and associated membrane rafts towards a chemokine gradient or a contact point with a cell displaying natural killer cell activating ligands. http://purl.obolibrary.org/obo/CL_4052008 crypt-bottom fibroblast http://purl.obolibrary.org/obo/CL_4052007 subepithelial intestinal fibroblast A subepithelial intestinal fibroblast that is located adjacent to the base of the crypt of Lieberkühn, near the intestinal stem cells. Characterized by low PDGFRα expression, this cell is crucial for maintaining the intestinal stem cell niche. Crypt-bottom fibroblast secretes key signaling molecules including canonical Wnt ligands (Wnt2, Wnt2b), Wnt potentiators (Rspo3), and BMP inhibitors (Grem1), which collectively regulate intestinal stem cell function and epithelial homeostasis. http://purl.obolibrary.org/obo/GO_0001773 myeloid dendritic cell activation http://purl.obolibrary.org/obo/GO_0002274 myeloid leukocyte activation The change in morphology and behavior of a dendritic cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. http://purl.obolibrary.org/obo/CL_4052009 crypt-top fibroblast http://purl.obolibrary.org/obo/CL_4052007 subepithelial intestinal fibroblast A subepithelial intestinal fibroblast that is located adjacent to the top of the crypt of Lieberkuhn. Characterized by high experession of PDGFRα, this cell secretes a range of signaling factors, including WNTs and BMPs, that drive epithelial differentiation, creating a gradient that regulates the balance between stem cell maintenance and differentiation. http://purl.obolibrary.org/obo/GO_0001774 microglial cell activation http://purl.obolibrary.org/obo/GO_0061900 glial cell activation The change in morphology and behavior of a microglial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. http://purl.obolibrary.org/obo/CL_4052010 pre-theca cell http://purl.obolibrary.org/obo/CL_0002174 follicular cell of ovary A stromal cell that serves as a precursor to the theca cell layers in the ovary growing follicles. This cell is present in the early stages of follicular growth, particularly in smaller follicles. Unlike mature theca cell, a pre-theca cell is initially non-steroidogenic and lacks luteinizing hormone receptors. http://purl.obolibrary.org/obo/GO_0001775 cell activation http://purl.obolibrary.org/obo/GO_0032501 multicellular organismal process A multicellular organismal process by which exposure to an activating factor such as a cellular or soluble ligand results in a change in the morphology or behavior of a cell. http://purl.obolibrary.org/obo/CL_4052011 follicle associated enterocyte http://purl.obolibrary.org/obo/CL_0000584 enterocyte An enterocyte found in the follicle-associated epithelium (FAE) that covers Peyer's patches and other mucosa-associated lymphoid tissues. This cell has reduced absorptive capacity and expresses higher levels of chemokines CCL20 and CXCL16, compared to regular villus enterocytes. It contributes to antigen sampling and immune interactions, supporting the specialized function of the FAE in mucosal immunity. http://purl.obolibrary.org/obo/GO_0001776 leukocyte homeostasis http://purl.obolibrary.org/obo/GO_0048872 homeostasis of number of cells The process of regulating the proliferation and elimination of cells of the immune system such that the total number of cells of a particular cell type within a whole or part of an organism is stable over time in the absence of an outside stimulus. http://purl.obolibrary.org/obo/CL_4052048 intercalated cell of salivary gland http://purl.obolibrary.org/obo/CL_1001596 salivary gland glandular cell A cuboidal epithelial cell that is part of the intercalated duct of salivary gland. This cell expresses proteins commonly associated with acinar cells and displays calcium signaling characteristics similar to secretory cells, indicating an active role in the secretory process rather than ion reabsorption. http://purl.obolibrary.org/obo/GO_0001777 T cell homeostatic proliferation http://purl.obolibrary.org/obo/GO_0042098 T cell proliferation The non-specific expansion of T cell populations within a whole or part of an organism to reach to a total number of T cells which will then remain stable over time in the absence of an external stimulus. http://purl.obolibrary.org/obo/CL_4052049 striated cell of salivary gland http://purl.obolibrary.org/obo/CL_1001596 salivary gland glandular cell An columnar/cuboidal epithelial cell that is part of the striated duct of salivary gland, characterized by basal striations formed by infoldings of the plasma membrane. This cell play a crucial role in modifying the electrolyte composition and concentration of saliva through active ion transport, particularly the absorption of sodium and secretion of potassium. http://purl.obolibrary.org/obo/GO_0001779 natural killer cell differentiation http://purl.obolibrary.org/obo/GO_0030101 natural killer cell activation The process in which a relatively unspecialized cell acquires the specialized features of a natural killer cell. http://purl.obolibrary.org/obo/GO_0120543 macromolecular conformation isomerase activity http://purl.obolibrary.org/obo/GO_0016853 isomerase activity Catalysis of a reaction that alters the macromolecular conformation of a molecule. http://purl.obolibrary.org/obo/GO_0001780 neutrophil homeostasis http://purl.obolibrary.org/obo/GO_0002262 myeloid cell homeostasis The process of regulating the proliferation and elimination of neutrophils such that the total number of neutrophils within a whole or part of an organism is stable over time in the absence of an outside stimulus. http://purl.obolibrary.org/obo/CL_0008060 GABA-Glut neuron http://purl.obolibrary.org/obo/CL_0000679 glutamatergic neuron A neuron that releases both gamma-aminobutyric acid and glutamate as vesicular neurotransmitters. http://purl.obolibrary.org/obo/GO_0001781 neutrophil apoptotic process http://purl.obolibrary.org/obo/GO_0071887 leukocyte apoptotic process Any apoptotic process in a neutrophil, any of the immature or mature forms of a granular leukocyte that in its mature form has a nucleus with three to five lobes connected by slender threads of chromatin, and cytoplasm containing fine inconspicuous granules and stainable by neutral dyes. http://purl.obolibrary.org/obo/CL_4307113 ABC NN_1 Pde11a arachnoid barrier cell (Mmus) http://purl.obolibrary.org/obo/CL_4301616 arachnoid barrier cell (Mmus) A arachnoid barrier cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Slc47a1 (Mmus), Pde11a (Mmus). It is distinguished from other ABC NN cells by expression of Pde11a. These cells are located in the brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5293 ABC NN_1. http://purl.obolibrary.org/obo/GO_0001782 B cell homeostasis http://purl.obolibrary.org/obo/GO_0002260 lymphocyte homeostasis The process of regulating the proliferation and elimination of B cells such that the total number of B cells within a whole or part of an organism is stable over time in the absence of an outside stimulus. http://purl.obolibrary.org/obo/CL_4307031 Astro-NT NN_1 Six3os1 astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301589 Astro-NT NN_1 astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Myoc (Mmus), Six3os1 (Mmus), Slc36a2 (Mmus). It is distinguished from other Astro-NT NN_1 cells by expression of Six3os1. These cells are located in the Striatum-like amygdalar nuclei, Olfactory areas, brain , in or close to the regions: Medial amygdalar nucleus . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5211 Astro-NT NN_1. http://purl.obolibrary.org/obo/GO_0001783 B cell apoptotic process http://purl.obolibrary.org/obo/GO_0070227 lymphocyte apoptotic process Any apoptotic process in a B cell, a lymphocyte of B lineage with the phenotype CD19-positive and capable of B cell mediated immunity. http://purl.obolibrary.org/obo/CL_4072010 A13 dopaminergic neuron http://purl.obolibrary.org/obo/CL_0012001 neuron of the forebrain A type of dopaminergic neuron located in the rostro-medial part of the zona incerta. It is involved in nociception and prehensile movement. http://purl.obolibrary.org/obo/GO_0001787 natural killer cell proliferation http://purl.obolibrary.org/obo/GO_0046651 lymphocyte proliferation The expansion of a natural killer cell population by cell division. http://purl.obolibrary.org/obo/CL_4307097 COP NN_1 Cck committed oligodendrocyte precursor (Mmus) http://purl.obolibrary.org/obo/CL_4301611 commited oligodendrocyte precursor (Mmus) A committed oligodendrocyte precursor of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of 9630013A20Rik (Mmus), Bmp4 (Mmus), Cck (Mmus), Ptger1 (Mmus). It is distinguished from other COP NN_1 cells by expression of Bmp4, Cck, Ptger1. These cells are located in the Isocortex, Olfactory areas, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5277 COP NN_1. http://purl.obolibrary.org/obo/GO_0001816 cytokine production http://purl.obolibrary.org/obo/GO_0032501 multicellular organismal process The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. http://purl.obolibrary.org/obo/CL_4307051 Astro-OLF NN_1 Greb1 astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301596 Astro-OLF NN_1 astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gja1 (Mmus), Chrdl1 (Mmus), Ano1 (Mmus), Il33 (Mmus). It is distinguished from other Astro-OLF NN_1 cells by expression of Greb1, Il33. These cells are located in the Olfactory areas, brain , in or close to the regions: Main olfactory bulb . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5231 Astro-OLF NN_1. http://purl.obolibrary.org/obo/GO_0001817 regulation of cytokine production http://purl.obolibrary.org/obo/GO_0051239 regulation of multicellular organismal process Any process that modulates the frequency, rate, or extent of production of a cytokine. http://purl.obolibrary.org/obo/CL_4301592 Astro-TE NN_2 astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4300359 astrocyte of cerebrum (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Hepacam (Mmus), E330013P04Rik (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1162 Astro-TE NN_2. http://purl.obolibrary.org/obo/GO_0001818 negative regulation of cytokine production http://purl.obolibrary.org/obo/GO_0051241 negative regulation of multicellular organismal process Any process that stops, prevents, or reduces the rate of production of a cytokine. http://purl.obolibrary.org/obo/CL_4301574 CB PLI Gly-Gaba_1 Purkinje layer interneuron (Mmus) http://purl.obolibrary.org/obo/CL_4300349 Purkinje layer interneuron (Mmus) A Purkinje layer interneuron of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Hmga2 (Mmus), Afap1l2 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1144 CB PLI Gly-Gaba_1. http://purl.obolibrary.org/obo/GO_0001819 positive regulation of cytokine production http://purl.obolibrary.org/obo/GO_0010628 positive regulation of gene expression Any process that activates or increases the frequency, rate or extent of production of a cytokine. http://purl.obolibrary.org/obo/CL_4307046 Astro-TE NN_3 Zic4 astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301593 Astro-TE NN_3 astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of S1pr1 (Mmus), Ranbp3l (Mmus), Emx2os (Mmus), Zic4 (Mmus). It is distinguished from other Astro-TE NN_3 cells by expression of Zic4. These cells are located in the Lateral septal complex, Isocortex, Olfactory areas , in or close to the regions: Lateral septal nucleus, rostral (rostroventral) part . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5226 Astro-TE NN_3. http://purl.obolibrary.org/obo/GO_0001820 serotonin secretion http://purl.obolibrary.org/obo/GO_0023061 signal release The regulated release of serotonin by a cell. Serotonin (5-hydroxytryptamine, or 5-HT) is a monoamine synthesized in serotonergic neurons in the central nervous system, enterochromaffin cells in the gastrointestinal tract and some immune system cells. http://purl.obolibrary.org/obo/CL_4301596 Astro-OLF NN_1 astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4300360 olfactory areas astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Aqp4 (Mmus), Prss23 (Mmus), Igfbp2 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1166 Astro-OLF NN_1. http://purl.obolibrary.org/obo/GO_0001821 histamine secretion http://purl.obolibrary.org/obo/GO_0051608 histamine transport The regulated release of histamine by a cell or tissue. It is formed by decarboxylation of histidine and it acts through receptors in smooth muscle and in secretory systems. http://purl.obolibrary.org/obo/CL_4307040 Astro-TE NN_1 Lncpint astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301591 Astro-TE NN_1 astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Myoc (Mmus), Dio2 (Mmus), Lncpint (Mmus). It is distinguished from other Astro-TE NN_1 cells by expression of Myoc, Lncpint. These cells are located in the brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5220 Astro-TE NN_1. http://purl.obolibrary.org/obo/GO_0001822 kidney development http://purl.obolibrary.org/obo/GO_0048513 animal organ development The process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and/or excretes the end products of body metabolism in the form of urine. http://purl.obolibrary.org/obo/CL_4300348 DCO Il22 Gly-Gaba cerebellar neuron (Mmus) http://purl.obolibrary.org/obo/CL_0008059 GABA-Gly neuron A cerebellar neuron of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Tmem204 (Mmus), Slc6a5 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Subclass:308 DCO Il22 Gly-Gaba. http://purl.obolibrary.org/obo/GO_0001823 mesonephros development http://purl.obolibrary.org/obo/GO_0001822 kidney development The process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. In mammals, the mesonephros is the second of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the mesonephros will form the mature kidney. http://purl.obolibrary.org/obo/CL_4033102 superior cervical ganglion TH neuron http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron A sympathetic neuron that has the soma located in the superior cervical ganglion and expresses the marker tyrosine hydroxylase (TH). http://purl.obolibrary.org/obo/GO_0001824 blastocyst development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the blastocyst over time, from its formation to the mature structure. The mammalian blastocyst is a hollow ball of cells containing two cell types, the inner cell mass and the trophectoderm. The blastula follows the morula and precedes the gastrula in the developmental sequence. http://purl.obolibrary.org/obo/CL_0000388 tendon cell http://purl.obolibrary.org/obo/CL_1000307 fibroblast of dense regular elastic tissue An elongated fibroblast that is part of a tendon. Its cytoplasm is stretched between the collagen fibres of the tendon, and it possesses a central nucleus with a prominent nucleolus. Tendon cell has a well-developed rough endoplasmic reticulum, and it is responsible for the synthesis and turnover of tendon fibres and ground substance. http://purl.obolibrary.org/obo/GO_0001825 blastocyst formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The initial formation of a blastocyst from a solid ball of cells known as a morula. http://purl.obolibrary.org/obo/UBERON_0000310 breast http://purl.obolibrary.org/obo/UBERON_0034929 external soft tissue zone The upper ventral region of the torso of an organism. http://purl.obolibrary.org/obo/GO_0001826 inner cell mass cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires specialized features of an inner cell mass cell. http://purl.obolibrary.org/obo/UBERON_0006247 iliac pre-cartilage condensation http://purl.obolibrary.org/obo/UBERON_0015054 iliac endochondral element An iliac endochondral element that is composed primarily of a pre-cartilage condensation. http://purl.obolibrary.org/obo/GO_0001829 trophectodermal cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a trophectoderm cell. http://purl.obolibrary.org/obo/PATO_0000025 composition http://purl.obolibrary.org/obo/PATO_0000141 structure A single physical entity inhering in an bearer by virtue of the bearer's quantities or relative ratios of subparts. http://purl.obolibrary.org/obo/GO_0001831 trophectodermal cellular morphogenesis http://purl.obolibrary.org/obo/GO_0048598 embryonic morphogenesis The morphogenesis of trophectoderm cells. http://purl.obolibrary.org/obo/PATO_0000050 life span http://purl.obolibrary.org/obo/PATO_0000165 time A time quality inhering in a bearer by virtue of the bearer's expected maximum age. http://purl.obolibrary.org/obo/GO_0001832 blastocyst growth http://purl.obolibrary.org/obo/GO_0048589 developmental growth An increase in size of a blastocyst due to expansion of the blastocoelic cavity cell shape changes and cell proliferation. http://purl.obolibrary.org/obo/PATO_0000051 morphology http://purl.obolibrary.org/obo/PATO_0001241 physical object quality A quality of a single physical entity inhering in the bearer by virtue of the bearer's size or shape or structure. http://purl.obolibrary.org/obo/GO_0001833 inner cell mass cell proliferation http://purl.obolibrary.org/obo/GO_0008283 cell population proliferation The proliferation of cells in the inner cell mass. http://purl.obolibrary.org/obo/PATO_0000052 shape http://purl.obolibrary.org/obo/PATO_0000051 morphology A morphological quality inhering in a bearer by virtue of the bearer's ratios of distances between its features (points, edges, surfaces and also holes etc). http://purl.obolibrary.org/obo/GO_0001834 trophectodermal cell proliferation http://purl.obolibrary.org/obo/GO_0008283 cell population proliferation The proliferation of cells in the trophectoderm. http://purl.obolibrary.org/obo/PATO_0000057 occurrence http://purl.obolibrary.org/obo/PATO_0002323 temporal distribution quality A quality of a single process inhering in a bearer by virtue of the bearer's occurrence. http://purl.obolibrary.org/obo/GO_0001837 epithelial to mesenchymal transition http://purl.obolibrary.org/obo/GO_0048762 mesenchymal cell differentiation A transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. http://purl.obolibrary.org/obo/PATO_0000068 qualitative http://purl.obolibrary.org/obo/PATO_0000001 quality A quality of an entity that is descriptive or observational, typically not represented numerically. http://purl.obolibrary.org/obo/GO_0001838 embryonic epithelial tube formation http://purl.obolibrary.org/obo/GO_0072175 epithelial tube formation The morphogenesis of an embryonic epithelium into a tube-shaped structure. http://purl.obolibrary.org/obo/PATO_0000069 deviation (from_normal) http://purl.obolibrary.org/obo/PATO_0000068 qualitative A quality inhering in a bearer by virtue of the whether the bearer differs from normal or average. http://purl.obolibrary.org/obo/GO_0001839 neural plate morphogenesis http://purl.obolibrary.org/obo/GO_0016331 morphogenesis of embryonic epithelium The process in which the anatomical structures of the neural plate are generated and organized. The neural plate is a specialized region of columnar epithelial cells in the dorsal ectoderm that will give rise to nervous system tissue. http://purl.obolibrary.org/obo/PATO_0000117 size http://purl.obolibrary.org/obo/PATO_0000051 morphology A morphology quality inhering in a bearer by virtue of the bearer's physical magnitude. http://purl.obolibrary.org/obo/GO_0001840 neural plate development http://purl.obolibrary.org/obo/GO_0060429 epithelium development The process whose specific outcome is the progression of the neural plate over time, from its formation to the mature structure. The neural plate is a flat, thickened layer of ectodermal cells. The underlying dorsal mesoderm signals the ectodermal cells above it to elongate into columnar neural plate cells. The neural plate subsequently develops into the neural tube, which gives rise to the central nervous system. http://purl.obolibrary.org/obo/PATO_0000136 closure http://purl.obolibrary.org/obo/PATO_0000051 morphology A morphological quality pertaining to the degree to which an object contains an opening, aperture, orifice or vent. http://purl.obolibrary.org/obo/GO_0001841 neural tube formation http://purl.obolibrary.org/obo/GO_0001838 embryonic epithelial tube formation The formation of a tube from the flat layer of ectodermal cells known as the neural plate. This will give rise to the central nervous system. http://purl.obolibrary.org/obo/PATO_0000141 structure http://purl.obolibrary.org/obo/PATO_0000051 morphology A morphology quality inhering in a bearer by virtue of the bearer's relative position, shape, arrangements and connectivity of an organism's various parts; the pattern underlying its form. http://purl.obolibrary.org/obo/GO_0001842 neural fold formation http://purl.obolibrary.org/obo/GO_0060571 morphogenesis of an epithelial fold The process in which the neural fold is formed. The edges of the neural plate thicken and move up to form a U-shaped structure called the neural groove. http://purl.obolibrary.org/obo/PATO_0000150 texture http://purl.obolibrary.org/obo/PATO_0000051 morphology A morphologic quality inhering in a bearer by virtue of the bearer's relative size, organization and distribution of its surface elements or the representation or invention of the appearance of its surface; visual and tactile surface characteristics. http://purl.obolibrary.org/obo/GO_0001865 NK T cell differentiation http://purl.obolibrary.org/obo/GO_0046632 alpha-beta T cell differentiation The process in which a precursor cell type acquires the specialized features of a NK T cell. http://purl.obolibrary.org/obo/PATO_0000165 time http://purl.obolibrary.org/obo/PATO_0001018 physical quality A quality in which events occur in sequence. http://purl.obolibrary.org/obo/GO_0001866 NK T cell proliferation http://purl.obolibrary.org/obo/GO_0051132 NK T cell activation The expansion of a NK T cell population by cell division. http://purl.obolibrary.org/obo/PATO_0000261 maturity http://purl.obolibrary.org/obo/PATO_0001995 organismal quality A quality of a single physical entity which is held by a bearer when the latter exhibits a state of growth, differentiation, or development. http://purl.obolibrary.org/obo/GO_0001873 polysaccharide immune receptor activity http://purl.obolibrary.org/obo/GO_0038187 pattern recognition receptor activity Combining with a polysaccharide and transmitting the signal to initiate an innate immune response. A polysaccharide is a polymer of many (typically more than 10) monosaccharide residues linked glycosidically. http://purl.obolibrary.org/obo/PATO_0000402 branched http://purl.obolibrary.org/obo/PATO_0002009 branchiness A branchiness quality inhering in a bearer by virtue of the bearer's having branches. http://purl.obolibrary.org/obo/GO_0001885 endothelial cell development http://purl.obolibrary.org/obo/GO_0002064 epithelial cell development The progression of an endothelial cell over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/PATO_0000404 coiled http://purl.obolibrary.org/obo/PATO_0001794 coiling A shape quality inhering in a bearer by virtue of the bearer's being curled or wound (especially in concentric rings or spirals). http://purl.obolibrary.org/obo/GO_0001886 endothelial cell morphogenesis http://purl.obolibrary.org/obo/GO_0003382 epithelial cell morphogenesis The change in form (cell shape and size) that occurs during the differentiation of an endothelial cell. http://purl.obolibrary.org/obo/PATO_0000405 curled http://purl.obolibrary.org/obo/PATO_0000052 shape A shape quality inhering in a bearer by virtue of the bearer's having parallel chains in undulate fashion on the border. http://purl.obolibrary.org/obo/GO_0001889 liver development http://purl.obolibrary.org/obo/GO_0048732 gland development The process whose specific outcome is the progression of the liver over time, from its formation to the mature structure. The liver is an exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes. http://purl.obolibrary.org/obo/PATO_0000407 flat http://purl.obolibrary.org/obo/PATO_0002254 flattened A quality inhering in a bearer by virtue of the bearer's having a horizontal surface without a slope, tilt, or curvature. http://purl.obolibrary.org/obo/GO_0001890 placenta development http://purl.obolibrary.org/obo/GO_0048513 animal organ development The process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin. http://purl.obolibrary.org/obo/PATO_0000411 circular http://purl.obolibrary.org/obo/PATO_0000947 elliptic A shape quality inhering in a bearer by virtue of the bearer's being such that every part of the surface or the circumference is equidistant from the center. http://purl.obolibrary.org/obo/GO_0001892 embryonic placenta development http://purl.obolibrary.org/obo/GO_0048568 embryonic organ development The embryonically driven process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin. http://purl.obolibrary.org/obo/PATO_0000413 square http://purl.obolibrary.org/obo/PATO_0002317 parallelogram A shape quality inhering in a bearer by virtue of the bearer's having an equal-sided rectangular form. http://purl.obolibrary.org/obo/GO_0001893 maternal placenta development http://purl.obolibrary.org/obo/GO_0060135 maternal process involved in female pregnancy Maternally driven process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin. http://purl.obolibrary.org/obo/GO_0001894 tissue homeostasis http://purl.obolibrary.org/obo/GO_0060249 anatomical structure homeostasis A homeostatic process involved in the maintenance of an internal steady state within a defined tissue of an organism, including control of cellular proliferation and death and control of metabolic function. http://purl.obolibrary.org/obo/GO_0001906 cell killing http://purl.obolibrary.org/obo/GO_0009987 cellular process Any process in an organism that results in the killing of its own cells or those of another organism, including in some cases the death of the other organism. Killing here refers to the induction of death in one cell by another cell, not cell-autonomous death due to internal or other environmental conditions. http://purl.obolibrary.org/obo/GO_0001909 leukocyte mediated cytotoxicity http://purl.obolibrary.org/obo/GO_0002443 leukocyte mediated immunity The directed killing of a target cell by a leukocyte. http://purl.obolibrary.org/obo/GO_0001910 regulation of leukocyte mediated cytotoxicity http://purl.obolibrary.org/obo/GO_0031341 regulation of cell killing Any process that modulates the frequency, rate, or extent of leukocyte mediated cytotoxicity. http://purl.obolibrary.org/obo/GO_0001911 negative regulation of leukocyte mediated cytotoxicity http://purl.obolibrary.org/obo/GO_0031342 negative regulation of cell killing Any process that stops, prevents, or reduces the rate of leukocyte mediated cytotoxicity. http://purl.obolibrary.org/obo/GO_0001912 positive regulation of leukocyte mediated cytotoxicity http://purl.obolibrary.org/obo/GO_0031343 positive regulation of cell killing Any process that activates or increases the frequency, rate or extent of leukocyte mediated cytotoxicity. http://purl.obolibrary.org/obo/GO_0001913 T cell mediated cytotoxicity http://purl.obolibrary.org/obo/GO_0002456 T cell mediated immunity The directed killing of a target cell by a T cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors. http://purl.obolibrary.org/obo/GO_0001914 regulation of T cell mediated cytotoxicity http://purl.obolibrary.org/obo/GO_0002709 regulation of T cell mediated immunity Any process that modulates the frequency, rate, or extent of T cell mediated cytotoxicity. http://purl.obolibrary.org/obo/GO_0001915 negative regulation of T cell mediated cytotoxicity http://purl.obolibrary.org/obo/GO_0002710 negative regulation of T cell mediated immunity Any process that stops, prevents, or reduces the rate of T cell mediated cytotoxicity. http://purl.obolibrary.org/obo/GO_0001916 positive regulation of T cell mediated cytotoxicity http://purl.obolibrary.org/obo/GO_0002711 positive regulation of T cell mediated immunity Any process that activates or increases the frequency, rate or extent of T cell mediated cytotoxicity. http://purl.obolibrary.org/obo/GO_0001922 B-1 B cell homeostasis http://purl.obolibrary.org/obo/GO_0001782 B cell homeostasis The process of regulating the proliferation and elimination of B cells of the B-1 subset such that the total number of B-1 B cells within a whole or part of an organism is stable over time in the absence of an outside stimulus. B-1 B cells are a distinct subset of B cells characterized as being CD5 positive, found predominantly in the peritoneum, pleural cavities, and spleen, and enriched for self-reactivity. http://purl.obolibrary.org/obo/GO_0001923 B-1 B cell differentiation http://purl.obolibrary.org/obo/GO_0002335 mature B cell differentiation The process in which a hemopoietic stem cell acquires the specialized features of a B-1 B cell. B-1 B cells are a distinct subset of B cells characterized as being CD5 positive, found predominantly in the peritoneum, pleural cavities, and spleen, and enriched for self-reactivity. http://purl.obolibrary.org/obo/GO_0001924 regulation of B-1 B cell differentiation http://purl.obolibrary.org/obo/GO_0045577 regulation of B cell differentiation Any process that modulates the frequency, rate, or extent of B-1 B cell differentiation. B-1 B cells are a distinct subset of B cells characterized as being CD5 positive, found predominantly in the peritoneum, pleural cavities, and spleen, and enriched for self-reactivity. http://purl.obolibrary.org/obo/GO_0001925 negative regulation of B-1 B cell differentiation http://purl.obolibrary.org/obo/GO_0045578 negative regulation of B cell differentiation Any process that stops, prevents, or reduces the rate of B-1 B cell differentiation. http://purl.obolibrary.org/obo/GO_0001926 positive regulation of B-1 B cell differentiation http://purl.obolibrary.org/obo/GO_0045579 positive regulation of B cell differentiation Any process that activates or increases the frequency, rate or extent of B-1 B cell differentiation. http://purl.obolibrary.org/obo/GO_0001935 endothelial cell proliferation http://purl.obolibrary.org/obo/GO_0050673 epithelial cell proliferation The multiplication or reproduction of endothelial cells, resulting in the expansion of a cell population. Endothelial cells are thin flattened cells which line the inside surfaces of body cavities, blood vessels, and lymph vessels, making up the endothelium. http://purl.obolibrary.org/obo/GO_0001936 regulation of endothelial cell proliferation http://purl.obolibrary.org/obo/GO_0050678 regulation of epithelial cell proliferation Any process that modulates the frequency, rate, or extent of endothelial cell proliferation. http://purl.obolibrary.org/obo/GO_0001937 negative regulation of endothelial cell proliferation http://purl.obolibrary.org/obo/GO_0050680 negative regulation of epithelial cell proliferation Any process that stops, prevents, or reduces the rate or extent of endothelial cell proliferation. http://purl.obolibrary.org/obo/GO_0001938 positive regulation of endothelial cell proliferation http://purl.obolibrary.org/obo/GO_0050679 positive regulation of epithelial cell proliferation Any process that activates or increases the rate or extent of endothelial cell proliferation. http://purl.obolibrary.org/obo/PATO_0000460 abnormal http://purl.obolibrary.org/obo/PATO_0000069 deviation (from_normal) A quality inhering in a bearer by virtue of the bearer's deviation from normal or average. http://purl.obolibrary.org/obo/GO_0001940 male pronucleus http://purl.obolibrary.org/obo/GO_0045120 pronucleus The pronucleus originating from the spermatozoa that was involved in fertilization. http://purl.obolibrary.org/obo/PATO_0000461 normal http://purl.obolibrary.org/obo/PATO_0000068 qualitative A quality inhering in a bearer by virtue of the bearer's exhibiting no deviation from normal or average. http://purl.obolibrary.org/obo/GO_0001941 postsynaptic membrane organization http://purl.obolibrary.org/obo/GO_0061024 membrane organization A process which results in the assembly, arrangement of constituent parts, or disassembly of a postsynaptic membrane, the specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). http://purl.obolibrary.org/obo/PATO_0000586 increased size http://purl.obolibrary.org/obo/PATO_0002305 increased object quality A size quality which is relatively high. http://purl.obolibrary.org/obo/GO_0001942 hair follicle development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the hair follicle over time, from its formation to the mature structure. A hair follicle is a tube-like opening in the epidermis where the hair shaft develops and into which the sebaceous glands open. http://purl.obolibrary.org/obo/PATO_0000587 decreased size http://purl.obolibrary.org/obo/PATO_0002303 decreased object quality A size quality which is relatively low. http://purl.obolibrary.org/obo/GO_0001944 vasculature development http://purl.obolibrary.org/obo/GO_0048731 system development The process whose specific outcome is the progression of the vasculature over time, from its formation to the mature structure. The vasculature is an interconnected tubular multi-tissue structure that contains fluid that is actively transported around the organism. http://purl.obolibrary.org/obo/PATO_0000588 vestigial http://purl.obolibrary.org/obo/PATO_0000141 structure A quality inhering in a bearer by virtue of the bearer's being a remnant structure from earlier development or evolution. http://purl.obolibrary.org/obo/GO_0001945 lymph vessel development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of a lymph vessel over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/PATO_0000608 closed http://purl.obolibrary.org/obo/PATO_0000136 closure A morphological quality inhering in a bearer by virtue of the bearer's affording blocked passage or view. http://purl.obolibrary.org/obo/GO_0001946 lymphangiogenesis http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis Lymph vessel formation when new vessels emerge from the proliferation of pre-existing vessels. http://purl.obolibrary.org/obo/PATO_0000610 open http://purl.obolibrary.org/obo/PATO_0000136 closure A morphological quality inhering in a bearer by virtue of the bearer's affording unobstructed passage or view. http://purl.obolibrary.org/obo/GO_0001949 sebaceous gland cell differentiation http://purl.obolibrary.org/obo/GO_0009913 epidermal cell differentiation The process in which a relatively unspecialized epidermal cell acquires the specialized features of a sebaceous gland cell. http://purl.obolibrary.org/obo/PATO_0000690 discontinuous http://purl.obolibrary.org/obo/PATO_0000057 occurrence A quality of a single process inhering in a bearer by virtue of the bearer's being marked by breaks or interruptions. http://purl.obolibrary.org/obo/GO_0001955 blood vessel maturation http://purl.obolibrary.org/obo/GO_0071695 anatomical structure maturation A developmental process, independent of morphogenetic (shape) change, that is required for a blood vessel to attain its fully functional state. http://purl.obolibrary.org/obo/PATO_0000947 elliptic http://purl.obolibrary.org/obo/PATO_0002318 superelliptic A spheroid quality inhering in a bearer by virtue of the bearer's being oval with two axes of symmetry, as produced by a conical section. http://purl.obolibrary.org/obo/GO_0001956 positive regulation of neurotransmitter secretion http://purl.obolibrary.org/obo/GO_1903532 positive regulation of secretion by cell Any process that activates or increases the frequency, rate or extent of the regulated release of a neurotransmitter. http://purl.obolibrary.org/obo/PATO_0000957 opacity http://purl.obolibrary.org/obo/PATO_0001300 optical quality An optical quality which obtains by virtue of the ability of the bearer to absorb visible light. http://purl.obolibrary.org/obo/GO_0001957 intramembranous ossification http://purl.obolibrary.org/obo/GO_0036072 direct ossification Direct ossification that occurs within mesenchyme or an accumulation of relatively unspecialized cells. http://purl.obolibrary.org/obo/PATO_0000963 opaque http://purl.obolibrary.org/obo/PATO_0000957 opacity A optical quality inhering in a bearer by virtue of the bearer's not being clear; not transmitting or reflecting light or radiant energy. http://purl.obolibrary.org/obo/GO_0001958 endochondral ossification http://purl.obolibrary.org/obo/GO_0036075 replacement ossification Replacement ossification wherein bone tissue replaces cartilage. http://purl.obolibrary.org/obo/PATO_0000964 transparent http://purl.obolibrary.org/obo/PATO_0000957 opacity A optical quality inhering in a bearer by virtue of the bearer's lacking opacity. http://purl.obolibrary.org/obo/GO_0001959 regulation of cytokine-mediated signaling pathway http://purl.obolibrary.org/obo/GO_0060759 regulation of response to cytokine stimulus Any process that modulates the frequency, rate or extent of the cytokine mediated signaling pathway. http://purl.obolibrary.org/obo/PATO_0000992 viscosity http://purl.obolibrary.org/obo/PATO_0001548 quality of a liquid A physical quality of a fluid inhering in a bearer by virtue of the bearer's disposition to internal resistance to flow. http://purl.obolibrary.org/obo/GO_0001960 negative regulation of cytokine-mediated signaling pathway http://purl.obolibrary.org/obo/GO_0060761 negative regulation of response to cytokine stimulus Any process that stops, prevents, or reduces the frequency, rate or extent of the cytokine mediated signaling pathway. http://purl.obolibrary.org/obo/PATO_0000998 viscous http://purl.obolibrary.org/obo/PATO_0000992 viscosity A viscosity quality inhering in a bearer by virtue of the bearer's having viscosity. http://purl.obolibrary.org/obo/GO_0001961 positive regulation of cytokine-mediated signaling pathway http://purl.obolibrary.org/obo/GO_0060760 positive regulation of response to cytokine stimulus Any process that activates or increases the frequency, rate or extent of a cytokine mediated signaling pathway. http://purl.obolibrary.org/obo/PATO_0001018 physical quality http://purl.obolibrary.org/obo/PATO_0001241 physical object quality A quality of a physical entity that exists through action of continuants at the physical level of organisation in relation to other entities. http://purl.obolibrary.org/obo/GO_0001963 synaptic transmission, dopaminergic http://purl.obolibrary.org/obo/GO_0007268 chemical synaptic transmission The vesicular release of dopamine. from a presynapse, across a chemical synapse, the subsequent activation of dopamine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse. http://purl.obolibrary.org/obo/PATO_0001031 elasticity http://purl.obolibrary.org/obo/PATO_0001018 physical quality A physical quality inhering in a bearer by virtue of the bearer's disposition to recover its size and shape after deformation in any way. http://purl.obolibrary.org/obo/GO_0001974 blood vessel remodeling http://purl.obolibrary.org/obo/GO_0048771 tissue remodeling The reorganization or renovation of existing blood vessels. http://purl.obolibrary.org/obo/PATO_0001171 elastic http://purl.obolibrary.org/obo/PATO_0001031 elasticity An elasticity quality inhering in a bearer by virtue of the bearer's ability to recover its size and shape after deformation in any way. http://purl.obolibrary.org/obo/PATO_0001185 larval http://purl.obolibrary.org/obo/PATO_0000261 maturity A maturity quality inhering in a bearer by virtue of the bearer's indirect development, undergoing metamorphosis. http://purl.obolibrary.org/obo/GO_0001976 nervous system process involved in regulation of systemic arterial blood pressure http://purl.obolibrary.org/obo/GO_0050877 nervous system process The regulation of blood pressure mediated by detection of stimuli and a neurological response. http://purl.obolibrary.org/obo/PATO_0001190 juvenile http://purl.obolibrary.org/obo/PATO_0000261 maturity A maturity quality inhering in a bearer by virtue the bearer's being not fully grown or developed. http://purl.obolibrary.org/obo/GO_0001990 regulation of systemic arterial blood pressure by hormone http://purl.obolibrary.org/obo/GO_0050886 endocrine process The process in which hormones modulate the force with which blood passes through the circulatory system. A hormone is one of a group of substances formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells, in the same organism, upon which they have a specific regulatory action. http://purl.obolibrary.org/obo/PATO_0001236 process quality http://purl.obolibrary.org/obo/PATO_0000001 quality A quality which inheres in an process. http://purl.obolibrary.org/obo/GO_0001991 regulation of systemic arterial blood pressure by circulatory renin-angiotensin http://purl.obolibrary.org/obo/GO_0003081 regulation of systemic arterial blood pressure by renin-angiotensin The process in which angiotensinogen metabolites in the bloodstream modulate the force with which blood passes through the circulatory system. The process begins when renin is released and cleaves angiotensinogen. http://purl.obolibrary.org/obo/PATO_0001241 physical object quality http://purl.obolibrary.org/obo/PATO_0000001 quality A quality which inheres in a continuant. http://purl.obolibrary.org/obo/PATO_0001292 full-spectrum EM radiation quality http://purl.obolibrary.org/obo/PATO_0070060 quality of interaction of a substance with electromagnetic radiation An EM radiation quality that is independent of the EM wavelength range. http://purl.obolibrary.org/obo/GO_0001992 regulation of systemic arterial blood pressure by vasopressin http://purl.obolibrary.org/obo/GO_0001990 regulation of systemic arterial blood pressure by hormone The regulation of blood pressure mediated by the signaling molecule vasopressin. Vasopressin is produced in the hypothalamus, and affects vasoconstriction, and renal water transport. http://purl.obolibrary.org/obo/PATO_0001294 radiation reflective quality http://purl.obolibrary.org/obo/PATO_0001292 full-spectrum EM radiation quality A scalar EM radiation quality which obtains by the capacity of the bearer to scatter or reflect radiation. http://purl.obolibrary.org/obo/GO_0001999 renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure http://purl.obolibrary.org/obo/GO_0003071 renal system process involved in regulation of systemic arterial blood pressure The physiological response of the kidneys to a decrease in blood flow. http://purl.obolibrary.org/obo/PATO_0001297 reflectivity http://purl.obolibrary.org/obo/PATO_0001294 radiation reflective quality A radiation reflective quality inhering in a bearer by virtue of the ratio of the energy of a wave reflected from its surface to the energy possessed by the wave striking the bearer's surface. http://purl.obolibrary.org/obo/GO_0002001 renin secretion into blood stream http://purl.obolibrary.org/obo/GO_0023061 signal release The regulated release of renin into the blood stream by juxtoglomerular cells. http://purl.obolibrary.org/obo/PATO_0001300 optical quality http://purl.obolibrary.org/obo/PATO_0070060 quality of interaction of a substance with electromagnetic radiation An EM radiation quality in which the EM radiation is within the fiat range of the spectrum visible deemed to be light. http://purl.obolibrary.org/obo/GO_0002009 morphogenesis of an epithelium http://purl.obolibrary.org/obo/GO_0048729 tissue morphogenesis The process in which the anatomical structures of epithelia are generated and organized. An epithelium consists of closely packed cells arranged in one or more layers, that covers the outer surfaces of the body or lines any internal cavity or tube. http://purl.obolibrary.org/obo/PATO_0001365 spiny http://purl.obolibrary.org/obo/PATO_0001925 surface feature shape A surface feature shape quality inhering in a bearer by virtue of the bearer's having spines, thorns or similar thin projections on its surface. http://purl.obolibrary.org/obo/GO_0002011 morphogenesis of an epithelial sheet http://purl.obolibrary.org/obo/GO_0002009 morphogenesis of an epithelium The process in which the anatomical structures of an epithelial sheet are generated and organized. An epithelial sheet is a flat surface consisting of closely packed epithelial cells. http://purl.obolibrary.org/obo/PATO_0001393 euploid http://purl.obolibrary.org/obo/PATO_0001374 ploidy A ploidy quality inhering in a bearer by virtue of the bearer's containing an integral multiple of the monoploid number, possibly excluding the sex-determining chromosomes. http://purl.obolibrary.org/obo/GO_0002027 regulation of heart rate http://purl.obolibrary.org/obo/GO_0065008 regulation of biological quality Any process that modulates the frequency or rate of heart contraction. http://purl.obolibrary.org/obo/PATO_0001397 cellular potency http://purl.obolibrary.org/obo/PATO_0001396 cellular quality A cellular quality that arises by virtue of whether the bearer's disposition to differentiate into one or more mature cell types. http://purl.obolibrary.org/obo/GO_0002028 regulation of sodium ion transport http://purl.obolibrary.org/obo/GO_0010959 regulation of metal ion transport Any process that modulates the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/PATO_0001400 unipotent http://purl.obolibrary.org/obo/PATO_0001397 cellular potency A cellular potency that is the capacity to produce only one differentiated cell type. http://purl.obolibrary.org/obo/GO_0002036 regulation of L-glutamate import across plasma membrane http://purl.obolibrary.org/obo/GO_0010958 regulation of amino acid import across plasma membrane Any process that modulates the frequency, rate or extent of L-glutamate import into a cell. http://purl.obolibrary.org/obo/PATO_0001401 oligopotent http://purl.obolibrary.org/obo/PATO_0001397 cellular potency A cellular potency that is the capacity to form multiple differentiated cell types of a specific lineage and lack self renewing capacity. http://purl.obolibrary.org/obo/GO_0002037 negative regulation of L-glutamate import across plasma membrane http://purl.obolibrary.org/obo/GO_0034763 negative regulation of transmembrane transport Any process that stops, prevents or reduces the frequency, rate or extent of L-glutamate import into a cell. http://purl.obolibrary.org/obo/PATO_0001402 multipotent http://purl.obolibrary.org/obo/PATO_0001397 cellular potency A cellular potency that is the capacity to form multiple differentiated cell types. http://purl.obolibrary.org/obo/GO_0002038 positive regulation of L-glutamate import across plasma membrane http://purl.obolibrary.org/obo/GO_0034764 positive regulation of transmembrane transport Any process that activates or increases the frequency, rate or extent of L-glutamate import into a cell. http://purl.obolibrary.org/obo/PATO_0001404 nucleate quality http://purl.obolibrary.org/obo/PATO_0001396 cellular quality A cellular quality inhering in a bearer by virtue of bearer's number of nuclei. http://purl.obolibrary.org/obo/GO_0002052 positive regulation of neuroblast proliferation http://purl.obolibrary.org/obo/GO_2000179 positive regulation of neural precursor cell proliferation Any process that activates or increases the rate of neuroblast proliferation. http://purl.obolibrary.org/obo/PATO_0001405 anucleate http://purl.obolibrary.org/obo/PATO_0001404 nucleate quality A nucleate quality inhering in a bearer by virtue of the bearer's having no nucleus. http://purl.obolibrary.org/obo/GO_0002053 positive regulation of mesenchymal cell proliferation http://purl.obolibrary.org/obo/GO_0010464 regulation of mesenchymal cell proliferation The process of activating or increasing the rate or extent of mesenchymal cell proliferation. Mesenchymal cells are loosely organized embryonic cells. http://purl.obolibrary.org/obo/PATO_0001406 binucleate http://purl.obolibrary.org/obo/PATO_0001908 multinucleate A nucleate quality inhering in a bearer by virtue of the bearer's having two nuclei. http://purl.obolibrary.org/obo/GO_0002062 chondrocyte differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte. A chondrocyte is a polymorphic cell that forms cartilage. http://purl.obolibrary.org/obo/PATO_0001407 mononucleate http://purl.obolibrary.org/obo/PATO_0002505 nucleated A nucleate quality inhering in a bearer by virtue of the bearer's having one nucleus. http://purl.obolibrary.org/obo/GO_0002063 chondrocyte development http://purl.obolibrary.org/obo/GO_0048468 cell development The process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate. http://purl.obolibrary.org/obo/PATO_0001408 ciliated http://purl.obolibrary.org/obo/PATO_0001396 cellular quality A cellular quality inhering in a bearer by virtue of the bearer's having one or more cilia as a part. http://purl.obolibrary.org/obo/GO_0002064 epithelial cell development http://purl.obolibrary.org/obo/GO_0048468 cell development The process whose specific outcome is the progression of an epithelial cell over time, from its formation to the mature structure. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface. http://purl.obolibrary.org/obo/PATO_0001410 striated http://purl.obolibrary.org/obo/PATO_0000052 shape A shape quality inhering in a bearer by virtue of the bearer's being marked by narrow lines or grooves, usually parallel. http://purl.obolibrary.org/obo/GO_0002065 columnar/cuboidal epithelial cell differentiation http://purl.obolibrary.org/obo/GO_0030855 epithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a columnar/cuboidal epithelial cell. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube. http://purl.obolibrary.org/obo/PATO_0001501 immature http://purl.obolibrary.org/obo/PATO_0000261 maturity A quality inhering in a bearer by virtue of the bearer's lacking complete growth, differentiation, or development. http://purl.obolibrary.org/obo/GO_0002066 columnar/cuboidal epithelial cell development http://purl.obolibrary.org/obo/GO_0002064 epithelial cell development The process whose specific outcome is the progression of a columnar/cuboidal epithelial cell over time, from its formation to the mature structure. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube. http://purl.obolibrary.org/obo/PATO_0001509 functionality http://purl.obolibrary.org/obo/PATO_0001241 physical object quality A quality of a single physical entity that arises by virtue of whether the bearer exhibits the ability to perform a regular function(s). http://purl.obolibrary.org/obo/GO_0002067 glandular epithelial cell differentiation http://purl.obolibrary.org/obo/GO_0002065 columnar/cuboidal epithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a glandular epithelial cell. A glandular epithelial cell is a columnar/cuboidal epithelial cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland. http://purl.obolibrary.org/obo/PATO_0001543 flexibility http://purl.obolibrary.org/obo/PATO_0001546 quality of a solid A physical quality inhering in a bearer by virtue of the bearer's disposition to being turned, bowed, or twisted without breaking. http://purl.obolibrary.org/obo/GO_0002068 glandular epithelial cell development http://purl.obolibrary.org/obo/GO_0002066 columnar/cuboidal epithelial cell development The process whose specific outcome is the progression of a glandular epithelial cell over time, from its formation to the mature structure. A glandular epithelial cell is a columnar/cuboidal epithelial cell is a cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland. http://purl.obolibrary.org/obo/PATO_0001544 flexible http://purl.obolibrary.org/obo/PATO_0001543 flexibility A physical quality inhering in a bearer by virtue of the bearer's ability of being turned, bowed, or twisted without breaking. http://purl.obolibrary.org/obo/GO_0002069 columnar/cuboidal epithelial cell maturation http://purl.obolibrary.org/obo/GO_0002070 epithelial cell maturation The developmental process, independent of morphogenetic (shape) change, that is required for a columna/cuboidal epithelial cell to attain its fully functional state. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube. http://purl.obolibrary.org/obo/PATO_0001559 having extra function http://purl.obolibrary.org/obo/PATO_0002305 increased object quality A functionality quality which is held by the bearer when the latter is able to perform additional or different function(s). http://purl.obolibrary.org/obo/GO_0002070 epithelial cell maturation http://purl.obolibrary.org/obo/GO_0048469 cell maturation The developmental process, independent of morphogenetic (shape) change, that is required for an epithelial cell to attain its fully functional state. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface. http://purl.obolibrary.org/obo/PATO_0001579 contractility http://purl.obolibrary.org/obo/PATO_0001018 physical quality A physical quality that is the ability to contract or shrink. http://purl.obolibrary.org/obo/GO_0002071 glandular epithelial cell maturation http://purl.obolibrary.org/obo/GO_0002069 columnar/cuboidal epithelial cell maturation The developmental process, independent of morphogenetic (shape) change, that is required for a glandular epithelial cell to attain its fully functional state. A glandular epithelial cell is a columnar/cuboidal epithelial cell is a cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland. http://purl.obolibrary.org/obo/PATO_0001580 increased contractility http://purl.obolibrary.org/obo/PATO_0002305 increased object quality A contractility which is relatively high. http://purl.obolibrary.org/obo/GO_0002072 optic cup morphogenesis involved in camera-type eye development http://purl.obolibrary.org/obo/GO_0016331 morphogenesis of embryonic epithelium The invagination of the optic vesicle to form two-walled indentations, the optic cups, that will go on to form the retina. This process begins with the optic vesicle becoming a two-walled structure and its subsequent shape changes. It does not include the fate commitment of cells to become the pigmented retina and the neural retina. An example of this process is found in Mus musculus. http://purl.obolibrary.org/obo/PATO_0001581 decreased contractility http://purl.obolibrary.org/obo/PATO_0002303 decreased object quality A contractility which is relatively low. http://purl.obolibrary.org/obo/GO_0002074 extraocular skeletal muscle development http://purl.obolibrary.org/obo/GO_0060538 skeletal muscle organ development The process whose specific outcome is the progression of the extraocular skeletal muscle over time, from its formation to the mature structure. The extraocular muscle is derived from cranial mesoderm and controls eye movements. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. An example of this process is found in Mus musculus. http://purl.obolibrary.org/obo/GO_0002076 osteoblast development http://purl.obolibrary.org/obo/GO_0048468 cell development The process whose specific outcome is the progression of an osteoblast over time, from its formation to the mature structure. Osteoblast development does not include the steps involved in committing a cranial neural crest cell or an osteoprogenitor cell to an osteoblast fate. An osteoblast is a cell that gives rise to bone. http://purl.obolibrary.org/obo/GO_0002080 acrosomal membrane http://purl.obolibrary.org/obo/GO_0030667 secretory granule membrane The membrane that surrounds the acrosomal lumen. The acrosome is a special type of lysosome in the head of a spermatozoon that contains acid hydrolases and is concerned with the breakdown of the outer membrane of the ovum during fertilization. http://purl.obolibrary.org/obo/GO_0002085 inhibition of neuroepithelial cell differentiation http://purl.obolibrary.org/obo/GO_0048505 regulation of timing of cell differentiation Any process that prevents the activation of neuroepithelial cell differentiation. Neuroepithelial cell differentiation is the process in which epiblast cells acquire specialized features of neuroepithelial cells. http://purl.obolibrary.org/obo/GO_0002087 regulation of respiratory gaseous exchange by nervous system process http://purl.obolibrary.org/obo/GO_0050877 nervous system process A process carried out by the nervous system that is required for the proper control of respiratory gaseous exchange. This process occurs in the respiratory center of the brain in vertebrates. http://purl.obolibrary.org/obo/PATO_0001591 curvature http://purl.obolibrary.org/obo/PATO_0000052 shape A surface shape quality inhering in a bearer by virtue of the bearer's exhibiting a degree of bending. http://purl.obolibrary.org/obo/GO_0002088 lens development in camera-type eye http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the lens over time, from its formation to the mature structure. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus. http://purl.obolibrary.org/obo/PATO_0001603 increased life span http://purl.obolibrary.org/obo/PATO_0002305 increased object quality A life span which is relatively high. http://purl.obolibrary.org/obo/GO_0002089 lens morphogenesis in camera-type eye http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structures of the lens are generated and organized. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus. http://purl.obolibrary.org/obo/PATO_0001604 decreased life span http://purl.obolibrary.org/obo/PATO_0002303 decreased object quality A life span which is relatively low. http://purl.obolibrary.org/obo/GO_0002093 auditory receptor cell morphogenesis http://purl.obolibrary.org/obo/GO_0048667 cell morphogenesis involved in neuron differentiation Any process that alters the size or shape of an auditory receptor cell. http://purl.obolibrary.org/obo/PATO_0001690 contractile http://purl.obolibrary.org/obo/PATO_0001579 contractility A contractility quality inhering in a bearer by virtue of the bearer's ability of contracting or being contracted. http://purl.obolibrary.org/obo/GO_0002158 osteoclast proliferation http://purl.obolibrary.org/obo/GO_0070661 leukocyte proliferation The multiplication or reproduction of osteoclasts, resulting in the expansion of an osteoclast cell population. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue, which typically differentiates from monocytes. http://purl.obolibrary.org/obo/PATO_0001693 increased viscosity http://purl.obolibrary.org/obo/PATO_0002305 increased object quality A viscosity which relatively high. http://purl.obolibrary.org/obo/GO_0002159 desmosome assembly http://purl.obolibrary.org/obo/GO_0007043 cell-cell junction assembly A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a desmosome. A desmosome is a patch-like intercellular junction found in vertebrate tissues, consisting of parallel zones of two cell membranes, separated by an space of 25-35 nm, and having dense fibrillar plaques in the subjacent cytoplasm. http://purl.obolibrary.org/obo/PATO_0001694 decreased viscosity http://purl.obolibrary.org/obo/PATO_0002303 decreased object quality A viscosity which relatively low. http://purl.obolibrary.org/obo/GO_0002164 larval development http://purl.obolibrary.org/obo/GO_0009791 post-embryonic development The process whose specific outcome is the progression of the larva over time, from its formation to the mature structure. The larva is the early, immature form of an that at birth or hatching is fundamentally unlike its parent and must metamorphose before assuming the adult characters. http://purl.obolibrary.org/obo/PATO_0001701 mature http://purl.obolibrary.org/obo/PATO_0000261 maturity A quality inhering in a bearer by virtue of the bearer's exhibiting complete growth, differentiation, or development. http://purl.obolibrary.org/obo/GO_0002165 instar larval or pupal development http://purl.obolibrary.org/obo/GO_0009791 post-embryonic development The process whose specific outcome is the progression of the instar larva or pupa over time, from its formation to the mature structure. An example of this process is found in Drosophila melanogaster. http://purl.obolibrary.org/obo/PATO_0001735 liquid configuration http://purl.obolibrary.org/obo/PATO_0001548 quality of a liquid A physical quality inhering in a bearer by virtue of the bearer's parts having the arrangement which exhibits characteristics of liquids. http://purl.obolibrary.org/obo/GO_0002176 male germ cell proliferation http://purl.obolibrary.org/obo/GO_0036093 germ cell proliferation The multiplication or reproduction of male germ cells, resulting in the expansion of a cell population. http://purl.obolibrary.org/obo/PATO_0001736 solid configuration http://purl.obolibrary.org/obo/PATO_0001546 quality of a solid A physical quality inhering in a bearer by virtue of the bearer's parts having the arrangement which exhibits characteristics of solids. http://purl.obolibrary.org/obo/GO_0002181 cytoplasmic translation http://purl.obolibrary.org/obo/GO_0006412 translation The chemical reactions and pathways resulting in the formation of a protein in the cytoplasm. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein. http://purl.obolibrary.org/obo/PATO_0001748 invaginated http://purl.obolibrary.org/obo/PATO_0001857 concave A shape quality in which a portion of the outermost boundary of an entity folds in space such that a portion that was originally convex is now concave. http://purl.obolibrary.org/obo/GO_0002182 cytoplasmic translational elongation http://purl.obolibrary.org/obo/GO_0006414 translational elongation The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis in the cytoplasm. http://purl.obolibrary.org/obo/PATO_0001776 increased flexibility http://purl.obolibrary.org/obo/PATO_0002305 increased object quality A flexibility which is relatively high. http://purl.obolibrary.org/obo/GO_0002183 cytoplasmic translational initiation http://purl.obolibrary.org/obo/GO_0006413 translational initiation The process preceding formation of the peptide bond between the first two amino acids of a protein in the cytoplasm. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA. http://purl.obolibrary.org/obo/PATO_0001777 decreased flexibility http://purl.obolibrary.org/obo/PATO_0002303 decreased object quality A flexibility which is relatively low. http://purl.obolibrary.org/obo/GO_0002184 cytoplasmic translational termination http://purl.obolibrary.org/obo/GO_0006415 translational termination The process resulting in the release of a polypeptide chain from the ribosome in the cytoplasm, usually in response to a termination codon. http://purl.obolibrary.org/obo/PATO_0001794 coiling http://purl.obolibrary.org/obo/PATO_0000052 shape A shape quality inhering in a bearer by virtue of the bearer's being wound in a continuous series of loops. http://purl.obolibrary.org/obo/GO_0002200 somatic diversification of immune receptors http://purl.obolibrary.org/obo/GO_0002376 immune system process The somatic process allowing for the production of immune receptors whose specificity is not encoded in the germline genomic sequences. http://purl.obolibrary.org/obo/PATO_0001795 increased coiling http://purl.obolibrary.org/obo/PATO_0002305 increased object quality A coiling which is relatively high. http://purl.obolibrary.org/obo/GO_0002204 somatic recombination of immunoglobulin genes involved in immune response http://purl.obolibrary.org/obo/GO_0016447 somatic recombination of immunoglobulin gene segments The process in which immunoglobulin genes are formed through recombination of the germline genetic elements, also known as immunoglobulin gene segments, within a single locus following the induction of and contributing to an immune response. http://purl.obolibrary.org/obo/PATO_0001796 decreased coiling http://purl.obolibrary.org/obo/PATO_0002303 decreased object quality A coiling which is relatively low. http://purl.obolibrary.org/obo/GO_0002208 somatic diversification of immunoglobulins involved in immune response http://purl.obolibrary.org/obo/GO_0016445 somatic diversification of immunoglobulins The somatic process that results in the generation of sequence diversity of immunoglobulins after induction, and contributes to an immune response. http://purl.obolibrary.org/obo/PATO_0001857 concave http://purl.obolibrary.org/obo/PATO_0002005 concavity A shape quality in a bearer by virtue of the bearer's curving inward. http://purl.obolibrary.org/obo/GO_0002213 defense response to insect http://purl.obolibrary.org/obo/GO_0051707 response to other organism A response to protect an organism from a directly detected or perceived external threat from an insect or insects to that organism. http://purl.obolibrary.org/obo/PATO_0001870 crescent-shaped http://purl.obolibrary.org/obo/PATO_0002006 2-D shape A shape quality inhering in a circular disk by virtue of the bearer's having a segment of another circle removed from its edge, so that what remains is a shape enclosed by two circular arcs of different diameters which intersect at two points (usually in such a manner that the enclosed shape does not include the center of the original circle). http://purl.obolibrary.org/obo/GO_0002215 defense response to nematode http://purl.obolibrary.org/obo/GO_0051707 response to other organism A response to protect an organism from a directly detected or perceived external threat from a nematode or nematodes, which results in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack. http://purl.obolibrary.org/obo/PATO_0001871 reniform http://purl.obolibrary.org/obo/PATO_0002008 concave 3-D shape A concave 3-D shape quality inhering in a bearer by virtue of the bearer's having the shape of a kidney. http://purl.obolibrary.org/obo/GO_0002225 positive regulation of antimicrobial peptide production http://purl.obolibrary.org/obo/GO_0002784 regulation of antimicrobial peptide production Any process that activates or increases the frequency, rate, or extent of antimicrobial peptide production. http://purl.obolibrary.org/obo/PATO_0001872 cuboid http://purl.obolibrary.org/obo/PATO_0002007 convex 3-D shape A convex 3-D shape quality inhering in a bearer by virtue of the bearer's resemblance to a cube (a 3-D shape with a square cross section). http://purl.obolibrary.org/obo/GO_0002227 innate immune response in mucosa http://purl.obolibrary.org/obo/GO_0045087 innate immune response Any process of the innate immune response that takes place in the mucosal tissues. http://purl.obolibrary.org/obo/PATO_0001873 cylindrical http://purl.obolibrary.org/obo/PATO_0002007 convex 3-D shape A convex 3-D shape quality inhering in a bearer by virtue of the bearer's exhibiting a consistently-sized round cross section. http://purl.obolibrary.org/obo/GO_0002228 natural killer cell mediated immunity http://purl.obolibrary.org/obo/GO_0045087 innate immune response The promotion of an immune response by natural killer cells through direct recognition of target cells or through the release of cytokines. http://purl.obolibrary.org/obo/PATO_0001874 discoid http://purl.obolibrary.org/obo/PATO_0001873 cylindrical A shape quality inhering in a bearer by virtue of the bearer's being cylindrical, in which the height is less than the diameter. http://purl.obolibrary.org/obo/GO_0002232 leukocyte chemotaxis involved in inflammatory response http://purl.obolibrary.org/obo/GO_0030595 leukocyte chemotaxis The movement of an immune cell in response to an external stimulus contributing to an inflammatory response. http://purl.obolibrary.org/obo/PATO_0001908 multinucleate http://purl.obolibrary.org/obo/PATO_0002505 nucleated A nucleate quality inhering in a bearer by virtue of the bearer's having more than one nucleus. http://purl.obolibrary.org/obo/GO_0002233 leukocyte chemotaxis involved in immune response http://purl.obolibrary.org/obo/GO_0030595 leukocyte chemotaxis The movement of an immune cell in response to an external stimulus a part of an immune response. http://purl.obolibrary.org/obo/PATO_0001910 folded http://purl.obolibrary.org/obo/PATO_0001925 surface feature shape A surface feature shape quality inhering in a bearer by virtue of the bearer's one part being layered over another connected part. http://purl.obolibrary.org/obo/GO_0002244 hematopoietic progenitor cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which precursor cell type acquires the specialized features of a hematopoietic progenitor cell, a class of cell types including myeloid progenitor cells and lymphoid progenitor cells. http://purl.obolibrary.org/obo/PATO_0001925 surface feature shape http://purl.obolibrary.org/obo/PATO_0000052 shape A surface shape quality inhering in a bearer by virtue of the bearer's shape of features present on its surface or outer shell. http://purl.obolibrary.org/obo/GO_0002246 wound healing involved in inflammatory response http://purl.obolibrary.org/obo/GO_0042060 wound healing The series of events that restore integrity to damaged tissue that contribute to an inflammatory response. http://purl.obolibrary.org/obo/PATO_0001979 lobed http://purl.obolibrary.org/obo/PATO_0000052 shape A shape quality inhering in a bearer by virtue of the bearer's being partly divided into a determinate number of regions. http://purl.obolibrary.org/obo/GO_0002249 lymphocyte anergy http://purl.obolibrary.org/obo/GO_0002507 tolerance induction Any process contributing to lymphocyte anergy, a state of functional inactivation. http://purl.obolibrary.org/obo/PATO_0001987 saccular http://purl.obolibrary.org/obo/PATO_0002014 structure, cavities A structural quality inhering in a bearer by virtue of the bearer's having a three dimensional cavity with a narrow or no opening, and often containing an anatomical substance. http://purl.obolibrary.org/obo/GO_0002250 adaptive immune response http://purl.obolibrary.org/obo/GO_0006955 immune response An immune response mediated by cells expressing specific receptors for antigens produced through a somatic diversification process, and allowing for an enhanced secondary response to subsequent exposures to the same antigen (immunological memory). http://purl.obolibrary.org/obo/PATO_0001988 quadrangular http://purl.obolibrary.org/obo/PATO_0002006 2-D shape A shape quality inhering in a bearer by virtue of the bearer's having four angles and four sides. http://purl.obolibrary.org/obo/GO_0002251 organ or tissue specific immune response http://purl.obolibrary.org/obo/GO_0006955 immune response An immune response taking place in an organ or tissues such as the liver, brain, mucosa, or nervous system tissues. http://purl.obolibrary.org/obo/PATO_0001992 cellularity http://purl.obolibrary.org/obo/PATO_0001995 organismal quality An organismal quality inhering in a bearer by virtue of the bearer's consisting cells. http://purl.obolibrary.org/obo/GO_0002252 immune effector process http://purl.obolibrary.org/obo/GO_0002376 immune system process Any process of the immune system that executes a component of an immune response. An effector immune process takes place after its activation. http://purl.obolibrary.org/obo/PATO_0001993 multicellular http://purl.obolibrary.org/obo/PATO_0001992 cellularity A cellularity quality inhering in a bearer by virtue of the bearer's consisting of more than one cell. http://purl.obolibrary.org/obo/GO_0002260 lymphocyte homeostasis http://purl.obolibrary.org/obo/GO_0001776 leukocyte homeostasis The process of regulating the proliferation and elimination of lymphocytes such that the total number of lymphocytes within a whole or part of an organism is stable over time in the absence of an outside stimulus. http://purl.obolibrary.org/obo/PATO_0002005 concavity http://purl.obolibrary.org/obo/PATO_0000052 shape Surface shape that refers to the inward or outward curvature of the surface. http://purl.obolibrary.org/obo/GO_0002262 myeloid cell homeostasis http://purl.obolibrary.org/obo/GO_0048872 homeostasis of number of cells The process of regulating the proliferation and elimination of myeloid cells such that the total number of myeloid cells within a whole or part of an organism is stable over time in the absence of an outside stimulus. http://purl.obolibrary.org/obo/PATO_0002006 2-D shape http://purl.obolibrary.org/obo/PATO_0000052 shape A shape that inheres in a 2 dimensional entity, such as a cross section or projection of a 3 dimensional entity. http://purl.obolibrary.org/obo/GO_0002263 cell activation involved in immune response http://purl.obolibrary.org/obo/GO_0002252 immune effector process A change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response. http://purl.obolibrary.org/obo/PATO_0002007 convex 3-D shape http://purl.obolibrary.org/obo/PATO_0002266 3-D shape A complete three dimensional shape in which for every line connecting pair of points on the object is within the object. Or: a shape lacking cavities. Contrast: concave. http://purl.obolibrary.org/obo/GO_0002264 endothelial cell activation involved in immune response http://purl.obolibrary.org/obo/GO_0042118 endothelial cell activation A change in the morphology or behavior of an endothelial cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response. http://purl.obolibrary.org/obo/PATO_0002008 concave 3-D shape http://purl.obolibrary.org/obo/PATO_0002266 3-D shape A complete three dimensional shape in which there is a line connecting pair of points on the object that lies outside the object. Or: a shape with cavities. Contrast: concave. http://purl.obolibrary.org/obo/GO_0002265 astrocyte activation involved in immune response http://purl.obolibrary.org/obo/GO_0048143 astrocyte activation A change in the morphology or behavior of an astrocyte resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response. http://purl.obolibrary.org/obo/PATO_0002009 branchiness http://purl.obolibrary.org/obo/PATO_0000052 shape A shape quality inhering in a bearer by virtue of the degree to which there are subdivisions or offshoots in a bearer entity. http://purl.obolibrary.org/obo/GO_0002266 follicular dendritic cell activation http://purl.obolibrary.org/obo/GO_0045321 leukocyte activation A change in the morphology or behavior of a follicular dendritic cell resulting from exposure to an activating factor such as a cellular or soluble ligand. http://purl.obolibrary.org/obo/PATO_0002011 neoplastic http://purl.obolibrary.org/obo/PATO_0000141 structure A structural quality which is held by a bearer when the latter's disposition the presence of abnormally proliferating masses of cells. http://purl.obolibrary.org/obo/GO_0002268 follicular dendritic cell differentiation http://purl.obolibrary.org/obo/GO_0097028 dendritic cell differentiation The process in which a relatively unspecialized precursor cell acquires the specialized features of a follicular dendritic cell. http://purl.obolibrary.org/obo/PATO_0002014 structure, cavities http://purl.obolibrary.org/obo/PATO_0000141 structure A structural quality that inheres in a bearer by virtue of the bearer's containing hollow areas. http://purl.obolibrary.org/obo/GO_0002269 leukocyte activation involved in inflammatory response http://purl.obolibrary.org/obo/GO_0045321 leukocyte activation A change in the morphology or behavior of a leukocyte resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an inflammatory response. http://purl.obolibrary.org/obo/PATO_0002039 biconcave http://purl.obolibrary.org/obo/PATO_0001857 concave A concave quality inhering in a bearer by virtue of the bearer's curving inward on both sides or surfaces. http://purl.obolibrary.org/obo/GO_0002270 plasmacytoid dendritic cell activation http://purl.obolibrary.org/obo/GO_0045321 leukocyte activation A change in the morphology or behavior of a plasmacytoid dendritic cell resulting from exposure to an activating factor such as a cellular or soluble ligand. http://purl.obolibrary.org/obo/PATO_0002045 dendritic http://purl.obolibrary.org/obo/PATO_0000402 branched A branched quality inhering in a bearer by virtue of the bearer's having smaller branches arising from larger branches. Resembling a tree in branching structure. http://purl.obolibrary.org/obo/GO_0002273 plasmacytoid dendritic cell differentiation http://purl.obolibrary.org/obo/GO_0097028 dendritic cell differentiation The process in which a relatively unspecialized hemopoietic precursor cell acquires the specialized features of a plasmacytoid dendritic cell. http://purl.obolibrary.org/obo/PATO_0002051 increased occurrence http://purl.obolibrary.org/obo/PATO_0002304 increased process quality An occurrence which is relatively high. http://purl.obolibrary.org/obo/GO_0002274 myeloid leukocyte activation http://purl.obolibrary.org/obo/GO_0045321 leukocyte activation A change in the morphology or behavior of a myeloid leukocyte resulting from exposure to an activating factor such as a cellular or soluble ligand. http://purl.obolibrary.org/obo/PATO_0002052 decreased occurrence http://purl.obolibrary.org/obo/PATO_0002302 decreased process quality An occurrence which is relatively low. http://purl.obolibrary.org/obo/GO_0002275 myeloid cell activation involved in immune response http://purl.obolibrary.org/obo/GO_0002366 leukocyte activation involved in immune response A change in the morphology or behavior of a myeloid cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response. http://purl.obolibrary.org/obo/PATO_0002064 fenestrated http://purl.obolibrary.org/obo/PATO_0000141 structure A structure quality inhering in a bearer by virtue of the bearer's delimited by a surface with holes. http://purl.obolibrary.org/obo/GO_0002276 basophil activation involved in immune response http://purl.obolibrary.org/obo/GO_0045575 basophil activation A change in morphology and behavior of a basophil resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the basophil has specifically bound via IgE bound to Fc-epsilonRI receptors, leading to the initiation or perpetuation of an immune response. http://purl.obolibrary.org/obo/PATO_0002078 hollow http://purl.obolibrary.org/obo/PATO_0002014 structure, cavities A quality inhering in a bearer by virtue of the bearer's having an empty space or cavity within. http://purl.obolibrary.org/obo/GO_0002277 myeloid dendritic cell activation involved in immune response http://purl.obolibrary.org/obo/GO_0002275 myeloid cell activation involved in immune response The change in morphology and behavior of a myeloid dendritic cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response. http://purl.obolibrary.org/obo/PATO_0002094 basophilic http://purl.obolibrary.org/obo/PATO_0070045 anatomical histological quality An affinity inhering in an anatomical structure by virtue of the bearer exhibiting a molecular interaction for basic dyes under specific pH conditions. http://purl.obolibrary.org/obo/GO_0002278 eosinophil activation involved in immune response http://purl.obolibrary.org/obo/GO_0043307 eosinophil activation The change in morphology and behavior of a eosinophil resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response. http://purl.obolibrary.org/obo/PATO_0002097 neoplastic, malignant http://purl.obolibrary.org/obo/PATO_0002011 neoplastic A disposition inhering in a tumour by virtue of the bearer's disposition to progress, invade surrounding tissues or metastasize. http://purl.obolibrary.org/obo/GO_0002279 mast cell activation involved in immune response http://purl.obolibrary.org/obo/GO_0045576 mast cell activation The change in morphology and behavior of a mast cell resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the mast cell has specifically bound via IgE bound to Fc-epsilonRI receptors, leading to the initiation or perpetuation of an immune response. http://purl.obolibrary.org/obo/PATO_0002124 laminar http://purl.obolibrary.org/obo/PATO_0000141 structure A quality inhering in a bearer by virtue of the bearer's processing the form of a thin plate sheet or layer. http://purl.obolibrary.org/obo/GO_0002280 monocyte activation involved in immune response http://purl.obolibrary.org/obo/GO_0042117 monocyte activation The change in morphology and behavior of a monocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response. http://purl.obolibrary.org/obo/PATO_0002198 quality of a substance http://purl.obolibrary.org/obo/PATO_0001018 physical quality A quality inhering in a bearer by virtue of its constitution. http://purl.obolibrary.org/obo/GO_0002281 macrophage activation involved in immune response http://purl.obolibrary.org/obo/GO_0042116 macrophage activation A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response. http://purl.obolibrary.org/obo/PATO_0002226 subcylindrical http://purl.obolibrary.org/obo/PATO_0001873 cylindrical A cylindrical shape quality inhering in a bearer by virtue of the bearer's being imperfectly cylindrical or approximately cylindrical. http://purl.obolibrary.org/obo/GO_0002282 microglial cell activation involved in immune response http://purl.obolibrary.org/obo/GO_0002281 macrophage activation involved in immune response The change in morphology and behavior of a microglial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response. http://purl.obolibrary.org/obo/PATO_0002254 flattened http://purl.obolibrary.org/obo/PATO_0001591 curvature A quality inhering in a bearer by virtue of the bearer's surface becoming more extended in a plane. http://purl.obolibrary.org/obo/GO_0002283 neutrophil activation involved in immune response http://purl.obolibrary.org/obo/GO_0042119 neutrophil activation The change in morphology and behavior of a neutrophil resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response. http://purl.obolibrary.org/obo/PATO_0002255 grooved http://purl.obolibrary.org/obo/PATO_0000150 texture Texture quality inhering in a bearer by virtue of the bearer's being marked with one or more channels. http://purl.obolibrary.org/obo/GO_0002285 lymphocyte activation involved in immune response http://purl.obolibrary.org/obo/GO_0046649 lymphocyte activation A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response. http://purl.obolibrary.org/obo/PATO_0002266 3-D shape http://purl.obolibrary.org/obo/PATO_0000052 shape A shape that inheres in a 3 dimensional entity. http://purl.obolibrary.org/obo/GO_0002286 T cell activation involved in immune response http://purl.obolibrary.org/obo/GO_0042110 T cell activation The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response. http://purl.obolibrary.org/obo/PATO_0002287 increased elasticity http://purl.obolibrary.org/obo/PATO_0002305 increased object quality An elasticity which is relatively high. http://purl.obolibrary.org/obo/GO_0002287 alpha-beta T cell activation involved in immune response http://purl.obolibrary.org/obo/GO_0046631 alpha-beta T cell activation The change in morphology and behavior of an alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response. http://purl.obolibrary.org/obo/PATO_0002288 decreased elasticity http://purl.obolibrary.org/obo/PATO_0002303 decreased object quality An elasticity which is relatively low. http://purl.obolibrary.org/obo/GO_0002292 T cell differentiation involved in immune response http://purl.obolibrary.org/obo/GO_0030217 T cell differentiation The process in which an antigenically naive T cell acquires the specialized features of an effector, regulatory, or memory T cell as part of an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells. http://purl.obolibrary.org/obo/PATO_0002299 tubular http://purl.obolibrary.org/obo/PATO_0002078 hollow A cylindrical shape that is hollow. http://purl.obolibrary.org/obo/GO_0002299 alpha-beta intraepithelial T cell differentiation http://purl.obolibrary.org/obo/GO_0046632 alpha-beta T cell differentiation The process in which a precursor cell type acquires the specialized features of an alpha-beta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways. http://purl.obolibrary.org/obo/PATO_0002300 increased quality http://purl.obolibrary.org/obo/PATO_0000069 deviation (from_normal) A quality that has a value that is increased compared to normal or average. http://purl.obolibrary.org/obo/GO_0002300 CD8-positive, alpha-beta intraepithelial T cell differentiation http://purl.obolibrary.org/obo/GO_0043374 CD8-positive, alpha-beta T cell differentiation The process in which a precursor cell type acquires the specialized features of a CD8-positive, alpha-beta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways. http://purl.obolibrary.org/obo/PATO_0002301 decreased quality http://purl.obolibrary.org/obo/PATO_0000069 deviation (from_normal) A quality that has a value that is decreased compared to normal or average. http://purl.obolibrary.org/obo/GO_0002301 CD4-positive, alpha-beta intraepithelial T cell differentiation http://purl.obolibrary.org/obo/GO_0043367 CD4-positive, alpha-beta T cell differentiation The process in which a precursor cell type acquires the specialized features of a CD4-positive, alpha-beta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways. http://purl.obolibrary.org/obo/PATO_0002302 decreased process quality http://purl.obolibrary.org/obo/PATO_0002301 decreased quality A quality of a process that has a value that is decreased compared to normal or average. http://purl.obolibrary.org/obo/GO_0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response http://purl.obolibrary.org/obo/GO_0043374 CD8-positive, alpha-beta T cell differentiation The process in which an antigenically naive CD8-positive, alpha-beta T cell acquires the specialized features of an effector, regulatory, or memory T cell as part of an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells. http://purl.obolibrary.org/obo/PATO_0002303 decreased object quality http://purl.obolibrary.org/obo/PATO_0002301 decreased quality A quality of an object that has a value that is decreased compared to normal or average. http://purl.obolibrary.org/obo/PATO_0002304 increased process quality http://purl.obolibrary.org/obo/PATO_0002300 increased quality A quality of a process that has a value that is increased compared to normal or average. http://purl.obolibrary.org/obo/GO_0002304 gamma-delta intraepithelial T cell differentiation http://purl.obolibrary.org/obo/GO_0042492 gamma-delta T cell differentiation The process in which a precursor cell type acquires the specialized features of a gamma-delta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways. http://purl.obolibrary.org/obo/PATO_0002305 increased object quality http://purl.obolibrary.org/obo/PATO_0002300 increased quality A quality of an object that has a value that is increased compared to normal or average. http://purl.obolibrary.org/obo/GO_0002305 CD8-positive, gamma-delta intraepithelial T cell differentiation http://purl.obolibrary.org/obo/GO_0002304 gamma-delta intraepithelial T cell differentiation The process in which a precursor cell type acquires the specialized features of a CD8-positive, gamma-delta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways. http://purl.obolibrary.org/obo/PATO_0002309 fiber shaped http://purl.obolibrary.org/obo/PATO_0002226 subcylindrical A convex 3-D shape quality inhering in a bearer by virtue of the bearer's exhibiting a by virtue of the bearer's exhibiting a consistently sized and approximately round cross-section along its length, which is many times larger than its diameter. http://purl.obolibrary.org/obo/PATO_0002312 segmented http://purl.obolibrary.org/obo/PATO_0000141 structure Consisting of segments or similar parts arranged in a longitudinal series. http://purl.obolibrary.org/obo/GO_0002306 CD4-positive gamma-delta intraepithelial T cell differentiation http://purl.obolibrary.org/obo/GO_0002304 gamma-delta intraepithelial T cell differentiation The process in which a precursor cell type acquires the specialized features of a CD4-positive, gamma-delta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways. http://purl.obolibrary.org/obo/PATO_0002317 parallelogram http://purl.obolibrary.org/obo/PATO_0001988 quadrangular A convex quadrilateral is a parallelogram if and only if any one of the following statements are true: 1. Each diagonal divides the quadrilateral into two congruent triangles with the same orientation. 2. The opposite sides are congruent in pairs. 3. The diagonals bisect each other. 4. The opposite angles are congruent in pairs. 5. The sum of the squares of the sides equals the sum of the squares of the diagonals. (This is the parallelogram law) 6.It possesses rotational symmetry. 7.One pair of opposite sides are parallel and congruent. 8.Two pairs of adjacent angles are supplementary. http://purl.obolibrary.org/obo/GO_0002307 CD8-positive, alpha-beta regulatory T cell differentiation http://purl.obolibrary.org/obo/GO_0045066 regulatory T cell differentiation The process in which a precursor cell type acquires the specialized features of a CD8-positive, alpha-beta regulatory T cell. http://purl.obolibrary.org/obo/PATO_0002318 superelliptic http://purl.obolibrary.org/obo/PATO_0002006 2-D shape A shape constituting a transition between a rectangle and a circle; a closed curve, of which the circle and ellipse are special cases, whose parametric equation is x = a.cos2/rt, y = b.cos2/rt http://purl.obolibrary.org/obo/GO_0002308 CD8-positive, alpha-beta cytotoxic T cell differentiation http://purl.obolibrary.org/obo/GO_0045065 cytotoxic T cell differentiation The process in which a precursor cell type acquires the specialized features of a CD8-positive, alpha-beta cytotoxic T cell. http://purl.obolibrary.org/obo/PATO_0002323 temporal distribution quality http://purl.obolibrary.org/obo/PATO_0002062 physical quality of a process A temporal distribution pattern of process occurrences within a regulation/reference process. http://purl.obolibrary.org/obo/GO_0002309 T cell proliferation involved in immune response http://purl.obolibrary.org/obo/GO_0042098 T cell proliferation The expansion of a T cell population by cell division as part of an immune response. http://purl.obolibrary.org/obo/PATO_0002353 activation quality http://purl.obolibrary.org/obo/PATO_0001509 functionality A quality that inheres in a bearer in virtue of its realizing one of its functions. http://purl.obolibrary.org/obo/GO_0002312 B cell activation involved in immune response http://purl.obolibrary.org/obo/GO_0042113 B cell activation The change in morphology and behavior of a mature or immature B cell during an immune response, resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. http://purl.obolibrary.org/obo/PATO_0002354 active http://purl.obolibrary.org/obo/PATO_0002353 activation quality A quality of an physical object that is currently realizing one of its functions. http://purl.obolibrary.org/obo/GO_0002313 mature B cell differentiation involved in immune response http://purl.obolibrary.org/obo/GO_0002335 mature B cell differentiation The process in which a naive B cell acquires the specialized features of a mature or memory B cell during an immune response. http://purl.obolibrary.org/obo/PATO_0002418 acidophilic http://purl.obolibrary.org/obo/PATO_0070045 anatomical histological quality An affinity inhering in an anatomical structure by virtue of the bearer exhibiting a molecular interaction for acidic dyes under specific pH conditions. http://purl.obolibrary.org/obo/GO_0002314 germinal center B cell differentiation http://purl.obolibrary.org/obo/GO_0002313 mature B cell differentiation involved in immune response The process in which a B cell in the spleen acquires the specialized features of a germinal center B cell. Germinal center B cells are rapidly cycling B cells which have downregulated IgD expression and exhibit high levels of binding by peanut agglutinin (PNA). http://purl.obolibrary.org/obo/PATO_0002420 amphiphilic http://purl.obolibrary.org/obo/PATO_0070045 anatomical histological quality Having both hydrophilic and hydrophobic (or lipophilic) groups. http://purl.obolibrary.org/obo/GO_0002315 marginal zone B cell differentiation http://purl.obolibrary.org/obo/GO_0002313 mature B cell differentiation involved in immune response The process in which a B cell in the spleen acquires the specialized features of a marginal zone B cell. Marginal zone B cells are localized in a distinct anatomical region of the spleen that represents the major antigen-filtering and scavenging area (by specialized macrophages resident there). It appears that they are preselected to express a BCR repertoire similar to B-1 B cells, biased toward bacterial cell wall constituents and senescent self-components (such as oxidized LDL). http://purl.obolibrary.org/obo/PATO_0002422 acinar http://purl.obolibrary.org/obo/PATO_0000141 structure Pertaining to the individual parts making up an aggregate fruit like a many-lobed "berry," such as a raspberry. http://purl.obolibrary.org/obo/GO_0002316 follicular B cell differentiation http://purl.obolibrary.org/obo/GO_0002313 mature B cell differentiation involved in immune response The process in which a B cell in the spleen acquires the specialized features of a follicular B cell. Follicular B cells are major population of mature recirculating B cells in the spleen and are located in the B-cell follicle region. http://purl.obolibrary.org/obo/PATO_0002444 mineralized http://purl.obolibrary.org/obo/PATO_0000025 composition A composition quality inhering in a bearer by virtue of the bearer's being composed of or possessing inorganic material. http://purl.obolibrary.org/obo/GO_0002317 plasma cell differentiation http://purl.obolibrary.org/obo/GO_0002313 mature B cell differentiation involved in immune response The process in which a B cell acquires the specialized features of a plasma cell. A plasma cell is a lymphocyte which develops from a B cell and produces high amounts of antibody. http://purl.obolibrary.org/obo/GO_0002318 myeloid progenitor cell differentiation http://purl.obolibrary.org/obo/GO_0002244 hematopoietic progenitor cell differentiation The process in which a precursor cell type acquires the specialized features of a myeloid progenitor cell. Myeloid progenitor cells include progenitor cells for any of the myeloid lineages. http://purl.obolibrary.org/obo/GO_0002319 memory B cell differentiation http://purl.obolibrary.org/obo/GO_0090715 immunological memory formation process The process in which a B cell acquires the specialized features of a memory B cell. Memory B cells are cells that can respond rapidly to antigen re-exposure by production of high-affinity antibody. http://purl.obolibrary.org/obo/PATO_0002462 collagenous http://purl.obolibrary.org/obo/PATO_0000025 composition A composition quality inhering in an bearer by virtue of the bearer's consisting of collagen. http://purl.obolibrary.org/obo/GO_0002320 lymphoid progenitor cell differentiation http://purl.obolibrary.org/obo/GO_0002244 hematopoietic progenitor cell differentiation The process in which a precursor cell type acquires the specialized features of a lymphoid progenitor cell. Lymphoid progenitor cells include progenitor cells for any of the lymphoid lineages. http://purl.obolibrary.org/obo/PATO_0002468 distensible http://purl.obolibrary.org/obo/PATO_0015008 distensibility A structure quality inhering in a bearer by virtue of the bearer's being capable of swelling or stretching. http://purl.obolibrary.org/obo/GO_0002321 natural killer cell progenitor differentiation http://purl.obolibrary.org/obo/GO_0002320 lymphoid progenitor cell differentiation The process in which a precursor cell type acquires the specialized features of a natural killer cell progenitor. http://purl.obolibrary.org/obo/PATO_0002478 transversely striated http://purl.obolibrary.org/obo/PATO_0001410 striated A shape quality inhering in a bearer by virtue of the bearer's being marked by narrow lines or grooves, usually parallel, that are oriented transversely relative to the long axis of the bearer. http://purl.obolibrary.org/obo/GO_0002322 B cell proliferation involved in immune response http://purl.obolibrary.org/obo/GO_0042100 B cell proliferation The expansion of a B cell population by cell division following B cell activation during an immune response. http://purl.obolibrary.org/obo/PATO_0002479 obliquely striated http://purl.obolibrary.org/obo/PATO_0001410 striated A shape quality inhering in a bearer by virtue of the bearer's being marked by narrow lines or grooves, usually parallel, that are oriented obliquely relative to the long axis of the bearer. http://purl.obolibrary.org/obo/GO_0002323 natural killer cell activation involved in immune response http://purl.obolibrary.org/obo/GO_0030101 natural killer cell activation The change in morphology and behavior of a natural killer cell resulting from exposure a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response. http://purl.obolibrary.org/obo/PATO_0002487 single organismal process quality http://purl.obolibrary.org/obo/PATO_0001236 process quality A quality inhering in a process by virtue of that process having exactly one organism as a participant. http://purl.obolibrary.org/obo/GO_0002327 immature B cell differentiation http://purl.obolibrary.org/obo/GO_0030183 B cell differentiation The process in which a precursor cell type acquires the specialized features of an immature B cell. http://purl.obolibrary.org/obo/PATO_0002505 nucleated http://purl.obolibrary.org/obo/PATO_0001404 nucleate quality A nucleate quality inhering in a bearer by virtue of the bearer's having one or more nucleus. http://purl.obolibrary.org/obo/GO_0002328 pro-B cell differentiation http://purl.obolibrary.org/obo/GO_0002320 lymphoid progenitor cell differentiation The process in which a precursor cell type acquires the specialized features of a pro-B cell. Pro-B cells are the earliest stage of the B cell lineage and undergo heavy chain D and J gene rearrangements, although they are not fully committed. http://purl.obolibrary.org/obo/PATO_0002506 alobate http://purl.obolibrary.org/obo/PATO_0001925 surface feature shape A surface feature shape quality inhering in a bearer by virtue of the bearer's not having undulating edges forming lobes. http://purl.obolibrary.org/obo/GO_0002329 pre-B cell differentiation http://purl.obolibrary.org/obo/GO_0002327 immature B cell differentiation The process in which a precursor cell type acquires the specialized features of a pre-B cell. Pre-B cells follow the pro-B cell stage of immature B cell differentiation and undergo rearrangement of heavy chain V, D, and J gene segments. http://purl.obolibrary.org/obo/PATO_0002507 keratinous http://purl.obolibrary.org/obo/PATO_0000025 composition A composition quality inhering in a bearer by virtue of the bearer's consisting of keratin. http://purl.obolibrary.org/obo/PATO_0010001 disconnected http://purl.obolibrary.org/obo/PATO_0000141 structure A structural quality inhering in the bearer by virtue of the bearer consisting of multiple structures lacking any physical connection to each other. http://purl.obolibrary.org/obo/GO_0002332 transitional stage B cell differentiation http://purl.obolibrary.org/obo/GO_0002327 immature B cell differentiation The process in which immature B cells from the bone marrow become mature B cells in the spleen. Transitional stage B cells are subdivided into transitional one (T1) and transitional two (T2) stages and are short-lived and functionally incompetent. http://purl.obolibrary.org/obo/PATO_0015006 polymeric http://purl.obolibrary.org/obo/PATO_0000141 structure A quality inhering in a structure by virtue of it consisting of many of repeated, similar or identical subunits, arranged in some orderly array. http://purl.obolibrary.org/obo/GO_0002335 mature B cell differentiation http://purl.obolibrary.org/obo/GO_0030183 B cell differentiation The process in which transitional stage B cells acquire the specialized features of mature B cells in the spleen. http://purl.obolibrary.org/obo/PATO_0015008 distensibility http://purl.obolibrary.org/obo/PATO_0000141 structure A quality inhering in a bearer by virtue of the extent to which the bearer is capable of being stretched or swollen. http://purl.obolibrary.org/obo/GO_0002337 B-1a B cell differentiation http://purl.obolibrary.org/obo/GO_0001923 B-1 B cell differentiation The process in which B cells acquire the specialized features of B-1a B cells. B-1a B cells are B-1 cells that express CD5 and arise from fetal liver precursors. http://purl.obolibrary.org/obo/UBERON_0035044 olfactory cortex layer 3 http://purl.obolibrary.org/obo/UBERON_0022303 nervous system cell part layer Deepest layer of olfactory cortex. http://purl.obolibrary.org/obo/GO_0002338 B-1b B cell differentiation http://purl.obolibrary.org/obo/GO_0001923 B-1 B cell differentiation The process in which B cells acquire the specialized features of B-1b B cells. B-1b B cells are B-1 cells that do not express CD5. http://purl.obolibrary.org/obo/UBERON_0035046 parotid gland intercalated duct http://purl.obolibrary.org/obo/UBERON_0014727 intercalated duct of salivary gland Any of the small intralobular tubular canal that leads directly from the serous acinus of the parotid gland to a striated (secretory) duct; in mouse, the intercalated ducts are short and narrow and are lined by low cuboidal epithelial cells with large central nuclei; they secrete bicarbonate ion into and absorb chloride ion from the acinar product. http://purl.obolibrary.org/obo/GO_0002339 B cell selection http://purl.obolibrary.org/obo/GO_0002376 immune system process The process dependent upon B cell antigen receptor signaling in response to self or foreign antigen through which B cells are selected for survival. http://purl.obolibrary.org/obo/UBERON_0035047 parotid gland striated duct http://purl.obolibrary.org/obo/UBERON_0014729 striated duct of salivary gland Any of the intralobular secretory duct of the parotid gland which connects an intercalated duct to an interlobular excretory duct; striated ducts are lined by cuboidal to columnar acidophilic cells and are so-named because of characteristic striations in the basal portions of the cells which are due to the alignment of mitochondria between deep infoldings of the basal cell membrane; the nucleus is in the central part of the cell above the striations; as they approach the excretory ducts, their diameter may exceed that of the acini; striated ducts reabsorb sodium and secrete potassium. http://purl.obolibrary.org/obo/GO_0002343 peripheral B cell selection http://purl.obolibrary.org/obo/GO_0002339 B cell selection Any B cell selection process that occurs in the periphery. http://purl.obolibrary.org/obo/UBERON_0035091 extrinsic post-anal tail muscle http://purl.obolibrary.org/obo/UBERON_0003665 post-anal tail muscle A post-anal tail that attaches outside the tail. http://purl.obolibrary.org/obo/GO_0002344 B cell affinity maturation http://purl.obolibrary.org/obo/GO_0002343 peripheral B cell selection The process in which B cells produce antibodies with increased antigen affinity. This is accomplished by somatic hypermutation and selection for B cells which produce higher affinity antibodies to antigen. http://purl.obolibrary.org/obo/UBERON_0035165 posterior surface of prostate http://purl.obolibrary.org/obo/UBERON_0035480 surface of prostate The flattened aspect of the prostate with a slight furrow facing the rectum and anus. http://purl.obolibrary.org/obo/GO_0002349 histamine production involved in inflammatory response http://purl.obolibrary.org/obo/GO_0002532 production of molecular mediator involved in inflammatory response The synthesis or release of histamine following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels. http://purl.obolibrary.org/obo/UBERON_0035403 hypophysial artery http://purl.obolibrary.org/obo/UBERON_0001637 artery An artery that supplies the pituitary gland. http://purl.obolibrary.org/obo/GO_0002351 serotonin production involved in inflammatory response http://purl.obolibrary.org/obo/GO_0002532 production of molecular mediator involved in inflammatory response The synthesis or release of serotonin following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels. http://purl.obolibrary.org/obo/UBERON_0035435 right suprarenal vein http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure A vein that drains blood from the right adrenal gland into the inferior vena cava. http://purl.obolibrary.org/obo/GO_0002358 B cell homeostatic proliferation http://purl.obolibrary.org/obo/GO_0042100 B cell proliferation The non-specific expansion of B cell populations within a whole or part of an organism to reach to a total number of B cells which will then remain stable over time in the absence of an external stimulus. http://purl.obolibrary.org/obo/UBERON_0035480 surface of prostate http://purl.obolibrary.org/obo/UBERON_0036215 anatomical surface region The external portion of the prostate including the anterior, inferolateral, lateral and posterior surfaces. http://purl.obolibrary.org/obo/GO_0002359 B-1 B cell proliferation http://purl.obolibrary.org/obo/GO_0042100 B cell proliferation The expansion of a B-1 B cell by cell division. Follows B cell activation. http://purl.obolibrary.org/obo/UBERON_0035483 left suprarenal vein http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure A vein that drains blood from the left adrenal gland into the left renal artery. http://purl.obolibrary.org/obo/GO_0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation http://purl.obolibrary.org/obo/GO_0045066 regulatory T cell differentiation The process in which a precursor cell type acquires the specialized features of a CD4-positive, CD25-positive, alpha-beta regulatory T cell. http://purl.obolibrary.org/obo/UBERON_0035523 anterior surface of prostate http://purl.obolibrary.org/obo/UBERON_0035480 surface of prostate The aspect of the prostate facing the pubic symphysis. http://purl.obolibrary.org/obo/GO_0002366 leukocyte activation involved in immune response http://purl.obolibrary.org/obo/GO_0045321 leukocyte activation A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response. http://purl.obolibrary.org/obo/UBERON_0035539 esophageal artery http://purl.obolibrary.org/obo/UBERON_0004573 systemic artery Any of several arteries that arise from the aorta and supply blood to the esophagus. http://purl.obolibrary.org/obo/GO_0002367 cytokine production involved in immune response http://purl.obolibrary.org/obo/GO_0002440 production of molecular mediator of immune response The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus contributing to an immune response, resulting in an increase in its intracellular or extracellular levels. http://purl.obolibrary.org/obo/UBERON_0035608 dura mater lymph vessel http://purl.obolibrary.org/obo/UBERON_0001473 lymphatic vessel Any lymph vessel that is located in the dura mater of the brain. http://purl.obolibrary.org/obo/GO_0002368 B cell cytokine production http://purl.obolibrary.org/obo/GO_0019724 B cell mediated immunity Any process that contributes to cytokine production by a B cell. http://purl.obolibrary.org/obo/UBERON_0035610 hair canal http://purl.obolibrary.org/obo/UBERON_0004111 anatomical conduit Tubular connection between the epidermal surface and the most distal part of the inner root sheath. Contains the hair shaft. http://purl.obolibrary.org/obo/GO_0002369 T cell cytokine production http://purl.obolibrary.org/obo/GO_0002456 T cell mediated immunity Any process that contributes to cytokine production by a T cell. http://purl.obolibrary.org/obo/UBERON_0035649 nerve of penis http://purl.obolibrary.org/obo/UBERON_0001021 nerve Any nerve that innervates the penis. http://purl.obolibrary.org/obo/GO_0002370 natural killer cell cytokine production http://purl.obolibrary.org/obo/GO_0002367 cytokine production involved in immune response Any process that contributes to cytokine production by a natural killer cell. http://purl.obolibrary.org/obo/UBERON_0035650 nerve of clitoris http://purl.obolibrary.org/obo/UBERON_0001021 nerve Any nerve that innervates the clitoris. http://purl.obolibrary.org/obo/UBERON_0035803 extrapyramidal tract system http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain A neural network located in the brain that is part of the motor system involved in the coordination of movement that is distinct from the pyramidal tract. http://purl.obolibrary.org/obo/UBERON_0035815 paracardial fat http://purl.obolibrary.org/obo/UBERON_0035814 pericardial fat Fat deposits in the mediastinum outside the parietal pericardium . http://purl.obolibrary.org/obo/UBERON_0035825 left adrenal gland cortex http://purl.obolibrary.org/obo/UBERON_0001235 adrenal cortex The thick outer layer of the adrenal gland that is in the left side of the abdomen. http://purl.obolibrary.org/obo/UBERON_0035826 left adrenal gland medulla http://purl.obolibrary.org/obo/UBERON_0001236 adrenal medulla The adrenal gland medulla that is in the left side of the abdomen. http://purl.obolibrary.org/obo/UBERON_0035827 right adrenal gland cortex http://purl.obolibrary.org/obo/UBERON_0001235 adrenal cortex The thick outer layer of the adrenal gland that is in the right side of the abdomen. http://purl.obolibrary.org/obo/UBERON_0035828 right adrenal gland medulla http://purl.obolibrary.org/obo/UBERON_0001236 adrenal medulla The adrenal gland medulla that is in the right side of the abdomen. http://purl.obolibrary.org/obo/UBERON_0035956 epididymal lumen http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space The lumen of the epididymis. http://purl.obolibrary.org/obo/UBERON_0035999 dopaminergic cell groups http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain Collections of neurons in the central nervous system that have been demonstrated by histochemical fluorescence to contain the neurotransmitter dopamine ( Fuxe-1970 ). http://purl.obolibrary.org/obo/UBERON_0036007 A13 dopaminergic cell group http://purl.obolibrary.org/obo/UBERON_0035999 dopaminergic cell groups A group of cells that fluoresce for dopamine and are distributed in clusters that, in the primate, are ventral and medial to the mammillothalamic tract of the hypothalamus; a few extend into the reuniens nucleus of the thalamus (Felten-1983). In the mouse A13 is located ventral to the mammillothalamic tract of the thalamus in the zona incerta (adapted from Brain Info). http://purl.obolibrary.org/obo/CL_0003036 M7 retinal ganglion cell http://purl.obolibrary.org/obo/CL_0000740 retinal ganglion cell A monostratified retinal ganglion cell with large soma and large dendritic field, with medium dendritic arbor, and has dendrites in layers 2 and 5. http://purl.obolibrary.org/obo/CL_0001087 effector memory CD4-positive, alpha-beta T cell, terminally differentiated http://purl.obolibrary.org/obo/CL_4030002 effector memory CD45RA-positive, alpha-beta T cell, terminally differentiated A CD4-positive, alpha beta memory T cell with the phenotype CD45RA-positive, CD45RO-negative, and CCR7-negative. http://purl.obolibrary.org/obo/CL_0003015 G11-ON retinal ganglion cell http://purl.obolibrary.org/obo/CL_4023032 ON retinal ganglion cell A G11 retinal ganglion cell that has post synaptic terminals in sublaminar layer S4 and is depolarized by illumination of its receptive field center. http://purl.obolibrary.org/obo/CL_0003035 M6 retinal ganglion cell http://purl.obolibrary.org/obo/CL_0000740 retinal ganglion cell A monostratified retinal ganglion cell that contains opsin. http://purl.obolibrary.org/obo/GO_0061938 protein localization to somatodendritic compartment http://purl.obolibrary.org/obo/GO_0008104 intracellular protein localization A process in which a protein is transported to or maintained in a location within the somatodendritic compartment. http://purl.obolibrary.org/obo/GO_0110057 regulation of blood vessel endothelial cell differentiation http://purl.obolibrary.org/obo/GO_0045601 regulation of endothelial cell differentiation Any process that modulates the frequency, rate or extent of blood vessel endothelial cell differentiation. http://purl.obolibrary.org/obo/GO_0002371 dendritic cell cytokine production http://purl.obolibrary.org/obo/GO_0002443 leukocyte mediated immunity Any process that contributes to cytokine production by a dendritic cell. http://purl.obolibrary.org/obo/GO_0110058 positive regulation of blood vessel endothelial cell differentiation http://purl.obolibrary.org/obo/GO_0045603 positive regulation of endothelial cell differentiation Any process that activates or increases the frequency, rate or extent of blood vessel endothelial cell differentiation. http://purl.obolibrary.org/obo/GO_0002372 myeloid dendritic cell cytokine production http://purl.obolibrary.org/obo/GO_0061082 myeloid leukocyte cytokine production Any process that contributes to cytokine production by a myeloid dendritic cell. http://purl.obolibrary.org/obo/GO_0110059 negative regulation of blood vessel endothelial cell differentiation http://purl.obolibrary.org/obo/GO_0045602 negative regulation of endothelial cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of blood vessel endothelial cell differentiation. http://purl.obolibrary.org/obo/GO_0002373 plasmacytoid dendritic cell cytokine production http://purl.obolibrary.org/obo/GO_0002371 dendritic cell cytokine production Any process that contributes to cytokine production by a plasmacytoid dendritic cell. http://purl.obolibrary.org/obo/GO_0140112 extracellular vesicle biogenesis http://purl.obolibrary.org/obo/GO_0044085 cellular component biogenesis The assembly and secretion a set of components to form an extracellular vesicule, a membrane-bounded vesicle that is released into the extracellular region. Extracellular vesicles include exosomes, microvesicles and apoptotic bodies, based on the mechanism by which they are released from cells and differentiated based on their size and content. http://purl.obolibrary.org/obo/GO_0002376 immune system process http://purl.obolibrary.org/obo/GO_0008150 biological_process Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats. http://purl.obolibrary.org/obo/GO_0140297 DNA-binding transcription factor binding http://purl.obolibrary.org/obo/GO_0008134 transcription factor binding Binding to a DNA-binding transcription factor, a protein that interacts with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. http://purl.obolibrary.org/obo/GO_0002377 immunoglobulin production http://purl.obolibrary.org/obo/GO_0002440 production of molecular mediator of immune response The appearance of immunoglobulin due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. http://purl.obolibrary.org/obo/CL_0008027 rod bipolar cell (sensu Mus) http://purl.obolibrary.org/obo/CL_0000751 rod bipolar cell A bipolar neuron found in the retina that is synapsed by rod photoreceptor cells. These neurons have axons that arborize and synapse to targets in inner plexiform layers 4 and 5 and depolarize in response to light. http://purl.obolibrary.org/obo/GO_0002381 immunoglobulin production involved in immunoglobulin-mediated immune response http://purl.obolibrary.org/obo/GO_0002377 immunoglobulin production The appearance of immunoglobulin due to biosynthesis or secretion following a cellular stimulus during an immune response, resulting in an increase in its intracellular or extracellular levels. http://purl.obolibrary.org/obo/CL_0008028 visual system neuron http://purl.obolibrary.org/obo/CL_0000540 neuron Any neuron that is capable of part of some visual perception. http://purl.obolibrary.org/obo/GO_0002384 hepatic immune response http://purl.obolibrary.org/obo/GO_0002251 organ or tissue specific immune response An immune response taking place in the liver. http://purl.obolibrary.org/obo/CL_0008031 cortical interneuron http://purl.obolibrary.org/obo/CL_0010012 cerebral cortex neuron An interneuron that has its soma located in the cerebral cortex. http://purl.obolibrary.org/obo/GO_0002385 mucosal immune response http://purl.obolibrary.org/obo/GO_0002251 organ or tissue specific immune response An immune response taking place in mucosal tissues, including those of the intestinal tract, nasal and upper respiratory tract, and genital tract. http://purl.obolibrary.org/obo/CL_0008032 rosehip neuron http://purl.obolibrary.org/obo/CL_0010011 cerebral cortex GABAergic interneuron A GABAergic interneuron in human cortical layer 1 that has large rosehip-shaped axonal boutons and compact arborization. http://purl.obolibrary.org/obo/GO_0002387 immune response in gut-associated lymphoid tissue http://purl.obolibrary.org/obo/GO_0006955 immune response Immune response taking place in the gut-associated lymphoid tissue (GALT). GALT includes Peyer's patches, appendix, and solitary lymph nodules. http://purl.obolibrary.org/obo/GO_0140352 export from cell http://purl.obolibrary.org/obo/GO_0009987 cellular process The directed movement of some substance from a cell, into the extracellular region. This may occur via transport across the plasma membrane or via exocytosis. http://purl.obolibrary.org/obo/GO_0002388 immune response in Peyer's patch http://purl.obolibrary.org/obo/GO_0002387 immune response in gut-associated lymphoid tissue Immune response taking place in the Peyer's patch, nodular lymphoid structures on the serosal surface of the small intestine. http://purl.obolibrary.org/obo/GO_0150104 transport across blood-brain barrier http://purl.obolibrary.org/obo/GO_0010232 vascular transport The directed movement of substances (e.g. macromolecules, small molecules, ions) through the blood-brain barrier. http://purl.obolibrary.org/obo/GO_0002389 tolerance induction in Peyer's patch http://purl.obolibrary.org/obo/GO_0002394 tolerance induction in gut-associated lymphoid tissue Tolerance induction taking place in the Peyer's patches. http://purl.obolibrary.org/obo/PR_000050216 receptor-type tyrosine-protein phosphatase C isoform CD45R http://purl.obolibrary.org/obo/PR_000001006 receptor-type tyrosine-protein phosphatase C A receptor-type tyrosine-protein phosphatase C that is a translation product of a transcript that minimally includes the region encoded by the variable exon 4(A). http://purl.obolibrary.org/obo/GO_0002394 tolerance induction in gut-associated lymphoid tissue http://purl.obolibrary.org/obo/GO_0002401 tolerance induction in mucosal-associated lymphoid tissue Tolerance induction taking place in the gut-associated lymphoid tissue (GALT). http://purl.obolibrary.org/obo/CL_0009026 enterocyte of appendix http://purl.obolibrary.org/obo/CL_1000405 epithelial cell of appendix An enterocyte that is a part of a vermiform appendix. http://purl.obolibrary.org/obo/GO_0002395 immune response in nasopharyngeal-associated lymphoid tissue http://purl.obolibrary.org/obo/GO_0002387 immune response in gut-associated lymphoid tissue An immune response taking place in the nasopharyngeal-associated lymphoid tissue (NALT). NALT includes the tonsils and adenoids. http://purl.obolibrary.org/obo/CL_4023127 arcuate nucleus of hypothalamus KNDy neuron http://purl.obolibrary.org/obo/CL_4023125 KNDy neuron a KNDy neuron that is located in the arcuate nucleus of the hypothalamus. http://purl.obolibrary.org/obo/GO_0002396 MHC protein complex assembly http://purl.obolibrary.org/obo/GO_0065003 protein-containing complex assembly The aggregation, arrangement and bonding together of a set of components to form an MHC protein complex. http://purl.obolibrary.org/obo/CL_4023130 kisspeptin neuron http://purl.obolibrary.org/obo/CL_2000029 central nervous system neuron A neuron that expresses kisspeptin. These neurons are predominantly located in the hypothalamus, but also found in other parts of the brain including the hippocampal dentate gyrus. http://purl.obolibrary.org/obo/GO_0002399 MHC class II protein complex assembly http://purl.obolibrary.org/obo/GO_0002396 MHC protein complex assembly The aggregation, arrangement and bonding together of a set of components to form an MHC class II protein complex. http://purl.obolibrary.org/obo/CL_4023125 KNDy neuron http://purl.obolibrary.org/obo/CL_4023123 hypothalamus kisspeptin neuron A hypothalamus kisspeptin neuron that coexpresses kisspeptin, neurokinin B and dynorphin. http://purl.obolibrary.org/obo/GO_0002400 tolerance induction in nasopharyngeal-associated lymphoid tissue http://purl.obolibrary.org/obo/GO_0002395 immune response in nasopharyngeal-associated lymphoid tissue Tolerance induction taking place in the nasopharyngeal-associated lymphoid tissue (NALT). http://purl.obolibrary.org/obo/CL_4023123 hypothalamus kisspeptin neuron http://purl.obolibrary.org/obo/CL_0012001 neuron of the forebrain A kisspeptin neuron that is located in the hypothalamus. These neurons project to and activate gonadotrophin-releasing hormone neurons (acting via the kisspeptin receptor) in the hypothalamus and stimulate the secretion of gonadotrophin-releasing hormone. http://purl.obolibrary.org/obo/GO_0002401 tolerance induction in mucosal-associated lymphoid tissue http://purl.obolibrary.org/obo/GO_0002427 mucosal tolerance induction Tolerance induction taking place in the mucosal-associated lymphoid tissue (MALT). http://purl.obolibrary.org/obo/CL_4023124 dentate gyrus kisspeptin neuron http://purl.obolibrary.org/obo/CL_4023062 dentate gyrus neuron A kisspeptin neuron that is located in the dentate gyrus of the hippocampus. http://purl.obolibrary.org/obo/GO_0002402 B cell tolerance induction in mucosal-associated lymphoid tissue http://purl.obolibrary.org/obo/GO_0002451 peripheral B cell tolerance induction Tolerance induction taking place in the mucosal-associated lymphoid tissue (MALT) mediated by B cells. http://purl.obolibrary.org/obo/CL_0009101 fibroblastic reticular cell http://purl.obolibrary.org/obo/CL_0000432 reticular cell A reticular cell involved in directing B cells and T cells to specific regions within a tissue. http://purl.obolibrary.org/obo/GO_0002403 T cell tolerance induction in mucosal-associated lymphoid tissue http://purl.obolibrary.org/obo/GO_0002458 peripheral T cell tolerance induction Tolerance induction taking place in the mucosal-associated lymphoid tissue (MALT) mediated by T cells. http://purl.obolibrary.org/obo/CL_0009103 lymph node marginal reticular cell http://purl.obolibrary.org/obo/CL_0009102 lymph node fibroblastic reticular cell A fibroblastic reticular cell found in the lymph node subcapsular sinus. http://purl.obolibrary.org/obo/GO_0002407 dendritic cell chemotaxis http://purl.obolibrary.org/obo/GO_0036336 dendritic cell migration The movement of a dendritic cell in response to an external stimulus. http://purl.obolibrary.org/obo/CL_0009108 lymphatic endothelial cell of subcapsular sinus floor http://purl.obolibrary.org/obo/CL_0009115 lymph node lymphatic vessel endothelial cell A lymphatic endothelial cell located in the subcapsular sinus floor of a lymph node. In human, it's characterized by a unique marker expression (TNFRSF9+). http://purl.obolibrary.org/obo/GO_0002408 myeloid dendritic cell chemotaxis http://purl.obolibrary.org/obo/GO_0097529 myeloid leukocyte migration The movement of a myeloid dendritic cell in response to an external stimulus. http://purl.obolibrary.org/obo/CL_0009107 lymphatic endothelial cell of subcapsular sinus ceiling http://purl.obolibrary.org/obo/CL_0009115 lymph node lymphatic vessel endothelial cell A lymphatic endothelial cell located in the subcapsular sinus ceiling of a lymph node. In human, it's characterized by a unique marker expression (NT5e+ and Caveolin-1+). http://purl.obolibrary.org/obo/GO_0002409 Langerhans cell chemotaxis http://purl.obolibrary.org/obo/GO_0002408 myeloid dendritic cell chemotaxis The movement of a Langerhans cell in response to an external stimulus. http://purl.obolibrary.org/obo/UBERON_8410071 subcapsular sinus ceiling http://purl.obolibrary.org/obo/UBERON_0000064 organ part The section of the lymph node capsule that faces the subcapsular sinus. In human, it's characterized by specific protein markers. http://purl.obolibrary.org/obo/GO_0002410 plasmacytoid dendritic cell chemotaxis http://purl.obolibrary.org/obo/GO_0002407 dendritic cell chemotaxis The movement of a plasmacytoid dendritic cell in response to an external stimulus. http://purl.obolibrary.org/obo/UBERON_8410072 subcapsular sinus floor http://purl.obolibrary.org/obo/UBERON_0000064 organ part The section of the lymph node cortex that faces the subcapsular sinus. In human, it's characterized by specific protein markers. http://purl.obolibrary.org/obo/GO_0002427 mucosal tolerance induction http://purl.obolibrary.org/obo/GO_0002462 tolerance induction to nonself antigen Tolerance induction taking place in the mucosal tissues. http://purl.obolibrary.org/obo/UBERON_8470000 placental blood http://purl.obolibrary.org/obo/UBERON_0000178 blood Blood located in the placenta. http://purl.obolibrary.org/obo/GO_0002432 granuloma formation http://purl.obolibrary.org/obo/GO_0002252 immune effector process The formation of nodular inflammatory lesions, usually small or granular, firm, persistent, well-structured, and containing compactly grouped T lymphocytes and modified phagocytes such as epithelioid cells, giant cells, and other macrophages. Granuloma formation represents a chronic inflammatory response initiated by various infectious and noninfectious agents. The center of a granuloma consists of fused macrophages, which can become necrotic. http://purl.obolibrary.org/obo/GO_0002440 production of molecular mediator of immune response http://purl.obolibrary.org/obo/GO_0010467 gene expression The synthesis or release of any molecular mediator of the immune response, resulting in an increase in its intracellular or extracellular levels. http://purl.obolibrary.org/obo/CL_4030012 kidney loop of Henle short descending thin limb epithelial cell http://purl.obolibrary.org/obo/CL_1001111 kidney loop of Henle thin descending limb epithelial cell Epithelial cell of the descending thin limb of the short loop (cortical) nephron limited to the outer medulla (mainly inner strip). It is known in some mammalian species that the short descending limb of the loop of Henle selectively expresses the serine protease Corin, the homeobox TF Uncx, and the urea channel Slc14a2. http://purl.obolibrary.org/obo/GO_0002441 histamine secretion involved in inflammatory response http://purl.obolibrary.org/obo/GO_0046879 hormone secretion The regulated release of histamine by a cell as part of an inflammatory response. http://purl.obolibrary.org/obo/CL_4030014 kidney loop of Henle long descending thin limb inner medulla epithelial cell http://purl.obolibrary.org/obo/CL_1001111 kidney loop of Henle thin descending limb epithelial cell Epithelial cell of the descending thin limb of the long loop (juxtamedullary) nephron that spans the inner medulla. It is known in some mammalian species that the long descending limb of the loop of Henle in the inner medulla selectively expresses the nuclear receptor Nr2e3, the Ig kappa chain Igkc, and the secreted protein dermokine (Dmkn). SLC14A2, which expresses a urea transporter, is also expressed in the inner medulla. http://purl.obolibrary.org/obo/GO_0002442 serotonin secretion involved in inflammatory response http://purl.obolibrary.org/obo/GO_0001820 serotonin secretion The regulated release of serotonin by a cell as part of an inflammatory response. http://purl.obolibrary.org/obo/CL_4030013 kidney loop of Henle long descending thin limb outer medulla epithelial cell http://purl.obolibrary.org/obo/CL_1001111 kidney loop of Henle thin descending limb epithelial cell Epithelial cell of the descending thin limb of the long loop (juxtamedullary) nephron that spans the outer medulla (inner stripe). It is known in some mammalian species that the long descending limb of the loop of Henle in the outer medulla selectively expresses the secreted activin-antagonist protein follistatin (Fst), the GPI-linked adhesion protein Cdh13, and the protein kinase Stk32a. http://purl.obolibrary.org/obo/GO_0002443 leukocyte mediated immunity http://purl.obolibrary.org/obo/GO_0002252 immune effector process Any process involved in the carrying out of an immune response by a leukocyte. http://purl.obolibrary.org/obo/CL_0004220 flag amacrine cell http://purl.obolibrary.org/obo/CL_0004251 narrow field retinal amacrine cell An amacrine cell with a small, asymteric dendritic field. http://purl.obolibrary.org/obo/GO_0002444 myeloid leukocyte mediated immunity http://purl.obolibrary.org/obo/GO_0002443 leukocyte mediated immunity Any process involved in the carrying out of an immune response by a myeloid leukocyte. http://purl.obolibrary.org/obo/GO_0140961 cellular detoxification of metal ion http://purl.obolibrary.org/obo/GO_1990748 cellular detoxification Any process carried out at the cellular level that reduces or removes the toxicity of a metal ion. http://purl.obolibrary.org/obo/GO_0002446 neutrophil mediated immunity http://purl.obolibrary.org/obo/GO_0002444 myeloid leukocyte mediated immunity Any process involved in the carrying out of an immune response by a neutrophil. http://purl.obolibrary.org/obo/UBERON_8600017 bronchopulmonary segment http://purl.obolibrary.org/obo/UBERON_0000063 organ subunit A discrete anatomical unit of the lung that is composed of a segmental bronchus and the lung tissue supplied by that bronchus. A bronchopulmonary segment exhibits a pyramidal shape, with its apex pointing towards the center of the lung and its base toward the pleural surface. http://purl.obolibrary.org/obo/GO_0002447 eosinophil mediated immunity http://purl.obolibrary.org/obo/GO_0002444 myeloid leukocyte mediated immunity Any process involved in the carrying out of an immune response by an eosinophil. http://purl.obolibrary.org/obo/CL_1100001 secretory epithelial cell http://purl.obolibrary.org/obo/CL_0000151 secretory cell An epithelial cell that is specialised for the synthesis and secretion of specific biomolecules. http://purl.obolibrary.org/obo/GO_0002448 mast cell mediated immunity http://purl.obolibrary.org/obo/GO_0002444 myeloid leukocyte mediated immunity Any process involved in the carrying out of an immune response by a mast cell. http://purl.obolibrary.org/obo/CL_4033085 diffuse bipolar 5 cell http://purl.obolibrary.org/obo/CL_0000749 ON-bipolar cell An ON diffuse bipolar cell that stratifies in the stratum 3 of the inner plexiform layer to make synapses with ON parasol ganglion cells. A diffuse bipolar 5 cell has high expression of MYO16 compared with other bipolar cells. http://purl.obolibrary.org/obo/GO_0002449 lymphocyte mediated immunity http://purl.obolibrary.org/obo/GO_0002443 leukocyte mediated immunity Any process involved in the carrying out of an immune response by a lymphocyte. http://purl.obolibrary.org/obo/CL_4033086 lipid-associated macrophage http://purl.obolibrary.org/obo/CL_4047053 TREM2-positive macrophage A tissue-resident macrophage that is associated with lipids. This cell responsible of anti-inflammatory functions, lipid accumulation and enhancing phagocytosis (Wculek et al., 2022, Liu et al., 2022). In mice and humans, a lipid-associated macrophage is characterized by the marker Trem2 (Jaitlin et al., 2019). http://purl.obolibrary.org/obo/GO_0002450 B cell antigen processing and presentation http://purl.obolibrary.org/obo/GO_0019882 antigen processing and presentation The process in which a B cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex. http://purl.obolibrary.org/obo/CL_4033087 placental resident macrophage http://purl.obolibrary.org/obo/CL_0000864 tissue-resident macrophage A tissue-resident macrophage that is part of the placenta. This cell helps preventing immunological rejection of the fetus by modulating the immune environment. A placental resident macrophage has high plasticity to adapt to the changing needs of each phase of pregnancy. http://purl.obolibrary.org/obo/GO_0002451 peripheral B cell tolerance induction http://purl.obolibrary.org/obo/GO_0019724 B cell mediated immunity Tolerance induction of mature B cells in the peripheral lymphoid tissues: the blood, lymph nodes, spleen, and mucosal-associated lymphoid tissue. http://purl.obolibrary.org/obo/CL_4033088 decidual resident macrophage http://purl.obolibrary.org/obo/CL_0000349 extraembryonic cell A resident macrophage that is part of the decidua. Some decidual macrophages are derived from maternal blood monocytes that are recruited to the uterus shortly after conception. The main functions of a decidual macrophage are implantation, placental development, immune regulation and vascular remodeling. http://purl.obolibrary.org/obo/GO_0002456 T cell mediated immunity http://purl.obolibrary.org/obo/GO_0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains Any process involved in the carrying out of an immune response by a T cell. http://purl.obolibrary.org/obo/CL_4033089 atretic follicular cell of ovary http://purl.obolibrary.org/obo/CL_0002174 follicular cell of ovary A follicular cell of ovary that has begun to degenerate and undergo atresia, a specialized apoptosis. This cell is found in an atretic follicle, which is an ovarian follicle that started to mature but failed to reach full development and instead regresses. http://purl.obolibrary.org/obo/GO_0002457 T cell antigen processing and presentation http://purl.obolibrary.org/obo/GO_0019882 antigen processing and presentation The process in which a T cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex. http://purl.obolibrary.org/obo/GO_0002458 peripheral T cell tolerance induction http://purl.obolibrary.org/obo/GO_0002517 T cell tolerance induction Tolerance induction of T cells in the periphery, in this case, any location in the body other than the thymus. http://purl.obolibrary.org/obo/CL_4033090 atretic granulosa cell http://purl.obolibrary.org/obo/CL_4033089 atretic follicular cell of ovary A granulosa cell that is undergoing atresia. This cell type displays distinct morphological alterations compared with a healthy granulosa cell, including pyknosis (nuclear condensation) and cellular shrinkage. http://purl.obolibrary.org/obo/CL_4033091 glycinergic-GABAergic amacrine cell http://purl.obolibrary.org/obo/CL_0008059 GABA-Gly neuron An amacrine cell that uses both GABA and glycine as neurotransmitters. http://purl.obolibrary.org/obo/GO_0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains http://purl.obolibrary.org/obo/GO_0002250 adaptive immune response An immune response mediated by lymphocytes expressing specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of germline gene segments encoding immunoglobulin superfamily domains. Recombined receptors for antigen encoded by immunoglobulin superfamily domains include T cell receptors and immunoglobulins (antibodies) produced by B cells. The first encounter with antigen elicits a primary immune response that is slow and not of great magnitude. T and B cells selected by antigen become activated and undergo clonal expansion. A fraction of antigen-reactive T and B cells become memory cells, whereas others differentiate into effector cells. The memory cells generated during the primary response enable a much faster and stronger secondary immune response upon subsequent exposures to the same antigen (immunological memory). An example of this is the adaptive immune response found in Mus musculus. http://purl.obolibrary.org/obo/CL_4033092 CD57-positive enterocyte http://purl.obolibrary.org/obo/CL_1000335 enterocyte of epithelium of intestinal villus An enterocyte that is part of a duodenal epithelium and expresses beta-1,3-glucuronyltransferase 1 (B3GAT1), also known as CD57 or HNK-1. http://purl.obolibrary.org/obo/GO_0002461 tolerance induction dependent upon immune response http://purl.obolibrary.org/obo/GO_0002507 tolerance induction Tolerance induction dependent upon an immune response, typically a response by a mature T or B cell in the periphery resulting tolerance towards an antigen via induction of anergy, cellular deletion, or regulatory T cell activation. http://purl.obolibrary.org/obo/CL_4033093 limbal epithelial stem cell of cornea http://purl.obolibrary.org/obo/CL_0000036 epithelial fate stem cell A stem cell that is part of the corneo-scleral limbus. This cell type resides at the basal layer of the epithelium and has a small size and high nuclear to cytoplasmatic ratio (Secker and Daniels, 2009). A limbal stem cell is responsible for corneal epithelial renewal and repair (Li et al., 2023), and to help maintain a clear corneal surface by preventing conjunctival epithelial cells from migrating onto the cornea (Wang et al., 2023). http://purl.obolibrary.org/obo/GO_0002462 tolerance induction to nonself antigen http://purl.obolibrary.org/obo/GO_0002461 tolerance induction dependent upon immune response Tolerance induction in response to nonself antigens. http://purl.obolibrary.org/obo/CL_4042028 immature neuron http://purl.obolibrary.org/obo/CL_2000029 central nervous system neuron A neuron in the central nervous system that is not committed to a differentiated fate, has not been newly derived from neurogenesis, and does not integrate into any circuit. http://purl.obolibrary.org/obo/GO_0002465 peripheral tolerance induction http://purl.obolibrary.org/obo/GO_0002461 tolerance induction dependent upon immune response Tolerance induction in the peripheral lymphoid tissues: blood, lymph nodes, spleen, and mucosal-associated lymphoid tissues. http://purl.obolibrary.org/obo/CL_4042029 cortical immature neuron http://purl.obolibrary.org/obo/CL_0010012 cerebral cortex neuron An immature neuron of a cerebral cortex. This neuron develops prenatally and remains in an immature state throughout the lifespan of the organism. http://purl.obolibrary.org/obo/GO_0002467 germinal center formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process in which germinal centers form. A germinal center is a specialized microenvironment formed when activated B cells enter lymphoid follicles. Germinal centers are the foci for B cell proliferation and somatic hypermutation. http://purl.obolibrary.org/obo/CL_4042030 candelabrum cell http://purl.obolibrary.org/obo/CL_4072102 Purkinje layer interneuron A GABAergic interneuron located in the Purkinje layer of the cerebellar cortex. This GABAergic interneuron type has a distinct morphology, it presents a small cell soma near the Purkinje cell layer (PCL), dendrites that extend to the surface of the molecular layer, and beaded axons that make local synapses contacts within the molecular layer. A candelabrum cell is excited by mossy fibers and granule cells but inhibited by Purkinje cells, and it inhibits molecular layer interneurons, which leads to the disinhibition of Purkinje cells. http://purl.obolibrary.org/obo/GO_0002468 dendritic cell antigen processing and presentation http://purl.obolibrary.org/obo/GO_0019882 antigen processing and presentation The process in which a dendritic cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex. http://purl.obolibrary.org/obo/CL_4042031 immune oligodendroglia http://purl.obolibrary.org/obo/CL_0000128 oligodendrocyte An oligodendrocyte of the central nervous system that exhibits immune properties such as self-presentation and non-self antigen presentation to T cells, phagocytosis of debris, and cytokine and chemokine production. Immune oligodendroglia is immunoreactive during inflammation, neurodegenerative disorders, chronic stress and major depressive disorder. http://purl.obolibrary.org/obo/GO_0002469 myeloid dendritic cell antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002468 dendritic cell antigen processing and presentation The process in which a myeloid dendritic cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex. http://purl.obolibrary.org/obo/CL_4042032 PAX6 GABAergic interneuron http://purl.obolibrary.org/obo/CL_4023064 caudal ganglionic eminence derived interneuron A transcriptomically distinct GABAergic neuron, located in the cerebral cortex and derived from the CGE, that expresses the transcript PAX6. http://purl.obolibrary.org/obo/GO_0002470 plasmacytoid dendritic cell antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002468 dendritic cell antigen processing and presentation The process in which a plasmacytoid dendritic cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex. http://purl.obolibrary.org/obo/CL_4042033 pro-opiomelanocortin neuron http://purl.obolibrary.org/obo/CL_0000165 neuroendocrine cell A neuron of the central nervous system that expresses POMC and synthesizes the POMC precursor polypeptide. This neuron type is located in the arcuate nucleus of the hypothalamus and in the nucleus tractus solitarius of the brainstem. The pro-opiomelanocortin neuron is part of the central melanocortin system and it is involved in regulating energy homeostasis, metabolism, and appetite. This neuronal type responds to hormonal signals such as levels of leptin and insulin, and its activation results in the release of α-melanocyte-stimulating hormone (α-MSH), which acts on melanocortin receptors to suppress food intake and increase energy expenditure. http://purl.obolibrary.org/obo/GO_0002471 monocyte antigen processing and presentation http://purl.obolibrary.org/obo/GO_0019882 antigen processing and presentation The process in which a monocyte expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex. http://purl.obolibrary.org/obo/CL_4042034 CGRP-expressing neuron http://purl.obolibrary.org/obo/CL_2000029 central nervous system neuron An interneuron neuron characterized by the expression of calcitonin gene-related peptide (CGRP), a 37-amino acid neuropeptide. This neuron type is involved in nociception and pain modulation by facilitating the transmission of nociceptive signals from peripheral sensory nerve endings to central nervous system structures. This neuron type is found in the dorsal root ganglia (DRG) and trigeminal ganglion, and the spinal cord dorsal horn. http://purl.obolibrary.org/obo/GO_0002472 macrophage antigen processing and presentation http://purl.obolibrary.org/obo/GO_0019882 antigen processing and presentation The process in which a macrophage expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex. http://purl.obolibrary.org/obo/CL_4042035 molecular layer interneuron http://purl.obolibrary.org/obo/CL_4023057 cerebellar inhibitory GABAergic interneuron A type of cerebellar inhibitory GABAergic interneuron that is located in the molecular layer of the cerebellum. This cell type inhibits Purkinje cells and other molecular layer interneurons. This interneuron plays a crucial role in regulating cerebellar output through feedforward inhibition and is characterized by its fast-spiking properties. http://purl.obolibrary.org/obo/GO_0002474 antigen processing and presentation of peptide antigen via MHC class I http://purl.obolibrary.org/obo/GO_0048002 antigen processing and presentation of peptide antigen The process in which an antigen-presenting cell expresses a peptide antigen on its cell surface in association with an MHC class I protein complex. Class I here refers to classical class I molecules. http://purl.obolibrary.org/obo/CL_4042036 melanin-concentrating hormone neuron http://purl.obolibrary.org/obo/CL_2000029 central nervous system neuron A neuron of the central nervous system with its soma primarily located in the lateral hypothalamic area and surrounding regions, including the zona incerta. This neuron type expresses melanin-concentrating hormone and is involved in regulating various physiological processes, including sleep, feeding behavior, and energy homeostasis. http://purl.obolibrary.org/obo/GO_0002478 antigen processing and presentation of exogenous peptide antigen http://purl.obolibrary.org/obo/GO_0048002 antigen processing and presentation of peptide antigen The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC protein complex. The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell. http://purl.obolibrary.org/obo/CL_4042037 sst GABAergic neuron of the striatum http://purl.obolibrary.org/obo/CL_0002613 striatum neuron A interneuron of the striatum expressing gamma-aminobutyric acid and somatostatin. This interneuron has a fusiform soma with a diameter between 9 - 25 µm, it has a long axon up to the length of 1mm. This neuron type displays a low threshold Ca2+ spike (LTS), a high input resistance, and the expression of long-lasting plateau potentials following depolarization from rest. http://purl.obolibrary.org/obo/GO_0002483 antigen processing and presentation of endogenous peptide antigen http://purl.obolibrary.org/obo/GO_0048002 antigen processing and presentation of peptide antigen The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC protein complex. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell. http://purl.obolibrary.org/obo/CL_4042038 rostral primary motorneuron http://purl.obolibrary.org/obo/CL_0000533 primary motor neuron (sensu Teleostei) A type of primary motor neuron situated in the rostral region of the spinal cord. RoP neurons extend their axons to innervate the ventral trunk musculature. http://purl.obolibrary.org/obo/GO_0002491 antigen processing and presentation of endogenous peptide antigen via MHC class II http://purl.obolibrary.org/obo/GO_0002495 antigen processing and presentation of peptide antigen via MHC class II The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class II protein complex. The peptide antigen is typically, but not always, processed from a whole protein. http://purl.obolibrary.org/obo/CL_4042039 caudal ganglionic eminence derived neuron http://purl.obolibrary.org/obo/CL_2000029 central nervous system neuron A neuron of the central nervous system that develops from a caudal ganglionic eminence. http://purl.obolibrary.org/obo/GO_0002495 antigen processing and presentation of peptide antigen via MHC class II http://purl.obolibrary.org/obo/GO_0048002 antigen processing and presentation of peptide antigen The process in which an antigen-presenting cell expresses a peptide antigen on its cell surface in association with an MHC class II protein complex. The peptide antigen is typically, but not always, processed from a whole protein. http://purl.obolibrary.org/obo/CL_4042040 glutamatergic neuron of the basal ganglia http://purl.obolibrary.org/obo/CL_2000029 central nervous system neuron A glutametergic neuron with its soma located in a basal ganglia. This neuron type is involved in motor control, decision making and learning. http://purl.obolibrary.org/obo/GO_0002496 proteolysis associated with antigen processing and presentation http://purl.obolibrary.org/obo/GO_0006508 proteolysis The hydrolysis of a peptide bond or bonds within a protein contributing to antigen processing and presentation. http://purl.obolibrary.org/obo/CL_4042041 middle primary motoneuron http://purl.obolibrary.org/obo/CL_0000533 primary motor neuron (sensu Teleostei) A type of primary motor neuron located in the middle region of the spinal cord. This primary motor neuron type is characterized by their distinct axonal pathways that innervate the middle trunk muscles. http://purl.obolibrary.org/obo/GO_0002500 proteolysis within lysosome associated with antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002496 proteolysis associated with antigen processing and presentation The hydrolysis of a peptide bond or bonds within a protein by lysosomal resident proteases contributing to antigen processing and presentation. http://purl.obolibrary.org/obo/CL_4047017 transit amplifying cell of gut http://purl.obolibrary.org/obo/CL_0009010 transit amplifying cell A transit amplifying cell of the gut epithelium, located in the wall of the intestinal crypt, just above intestinal stem cells from which they derive. These are rapidly dividing cells, capable of multiple rounds of division before differentiating into the various cell types of the gut epithelium (enterocyte, goblet, eneterodendocrine, paneth cells). http://purl.obolibrary.org/obo/GO_0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II http://purl.obolibrary.org/obo/GO_0019882 antigen processing and presentation The process in which an antigen-presenting cell expresses antigen (peptide or polysaccharide) on its cell surface in association with an MHC class II protein complex. http://purl.obolibrary.org/obo/CL_4047023 intestinal lamina propria fibroblast http://purl.obolibrary.org/obo/CL_0000151 secretory cell A fibroblast located in the lamina propria of the intestinal mucosa. This cell expresses PDGFRα and CD81 and is negative for α-smooth muscle actin (α-SMA). This cell is predominantly located in the small intestine adjacent to myofibroblasts surrounding the crypts. It is capable of synthesizing extracellular matrix components and structural proteins such as collagen and elastin. http://purl.obolibrary.org/obo/GO_0002507 tolerance induction http://purl.obolibrary.org/obo/GO_0002376 immune system process A process that directly activates any of the steps required for tolerance, a physiologic state in which the immune system does not react destructively against the components of an organism that harbors it or against antigens that are introduced to it. http://purl.obolibrary.org/obo/CL_4047025 type G cell of stomach http://purl.obolibrary.org/obo/CL_1000222 stomach neuroendocrine cell Any type G enteroendocrine cell that is part of some epithelium of stomach. http://purl.obolibrary.org/obo/GO_0002514 B cell tolerance induction http://purl.obolibrary.org/obo/GO_0002507 tolerance induction A process involving any mechanism for tolerance induction in B cells. http://purl.obolibrary.org/obo/CL_4047029 post-arteriole capillary cell http://purl.obolibrary.org/obo/CL_0002144 capillary endothelial cell An endothelial cell forming the walls of capillaries immediately downstream from arterioles, facilitating the exchange of substances between blood and interstitial fluid. This cell is characterized by a small diameter and may be continuous, fenestrated, or sinusoidal, depending on their location and function. This cell plays a crucial role in tissue oxygenation, nutrient delivery, and maintaining homeostasis within the microvascular network. http://purl.obolibrary.org/obo/GO_0002515 B cell anergy http://purl.obolibrary.org/obo/GO_0002514 B cell tolerance induction Any process contributing to anergy in B cells, a state of functional inactivation which is part of B cell tolerance induction. http://purl.obolibrary.org/obo/CL_4047030 pre-venule capillary cell http://purl.obolibrary.org/obo/CL_0002144 capillary endothelial cell A specialized endothelial cell located in the transition zone between capillaries and small venules in the microvascular system. It exhibits characteristics of both capillary and venous cells, expressing markers from both types. This cell plays a role in regulating blood flow and substance exchange between blood and tissues. http://purl.obolibrary.org/obo/GO_0002516 B cell deletion http://purl.obolibrary.org/obo/GO_1902742 apoptotic process involved in development The apoptotic death of B cells which is part of B cell tolerance induction. http://purl.obolibrary.org/obo/CL_4047032 secretory pericyte http://purl.obolibrary.org/obo/CL_0000669 pericyte A specialized pericyte located within the basement membrane of a blood capillary. This cell is characterized by its ability to produce and release a variety of bioactive molecules, collectively known as the pericyte secretome, including cytokines and regulators of angiogenesis. http://purl.obolibrary.org/obo/GO_0002517 T cell tolerance induction http://purl.obolibrary.org/obo/GO_0002507 tolerance induction A process involving any mechanism for tolerance induction in T cells. http://purl.obolibrary.org/obo/CL_4047034 smooth muscle cell of stomach http://purl.obolibrary.org/obo/CL_0000192 smooth muscle cell A smooth muscle cell that is part of the muscularis externa of the stomach wall. It is characterized by its fusiform shape, involuntary control, and ability to generate slow, sustained contractions. This cell is organized in distinct layers and is essential for gastric motility and digestion. http://purl.obolibrary.org/obo/GO_0002519 natural killer cell tolerance induction http://purl.obolibrary.org/obo/GO_0002507 tolerance induction Tolerance induction of natural killer cells. http://purl.obolibrary.org/obo/CL_4047035 stomach smooth muscle outer longitudinal layer cell http://purl.obolibrary.org/obo/CL_4047034 smooth muscle cell of stomach A specialized smooth muscle cell located in the outermost layer of the muscularis externa of the stomach wall. This cell is arranged longitudinally along the stomach's axis and is responsible for the contractions that facilitate food movement toward the pylorus. http://purl.obolibrary.org/obo/GO_0002520 immune system development http://purl.obolibrary.org/obo/GO_0048731 system development The process whose specific outcome is the progression of an organismal system whose objective is to provide calibrated responses by an organism to a potential internal or invasive threat, over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process. http://purl.obolibrary.org/obo/GO_0002521 leukocyte differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized hemopoietic precursor cell acquires the specialized features of a leukocyte. A leukocyte is an achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue. http://purl.obolibrary.org/obo/CL_4047101 liver-resident natural killer cell http://purl.obolibrary.org/obo/CL_0000623 natural killer cell A natural killer cell resident to the liver, located in the hepatic sinusoids. In humans this cell type is distinguished from circulating natural killer cells by CD49a or CD69 gene expression. Liver-resident natural killer cells have also been shown to express CCR5, EOMES, KLRB1, GZMK, and CXCR6 in humans. http://purl.obolibrary.org/obo/GO_0002522 leukocyte migration involved in immune response http://purl.obolibrary.org/obo/GO_0050900 leukocyte migration The movement of a leukocyte within or between different tissues and organs of the body as part of an immune response. http://purl.obolibrary.org/obo/CL_4052012 interna theca cell http://purl.obolibrary.org/obo/CL_0000593 androgen secreting cell A specialized theca cell that forms the inner, highly vascularized layer of the theca surrounding ovarian follicles. Originating from progenitor theca cells, the theca interna cell is steroidogenic, playing a crucial role in the production of androgens, which serves as a precursor for estrogen synthesis in granulosa cells. This cell expresses luteinizing hormone receptors, enabling it to respond to hormonal signals that regulate steroidogenesis. http://purl.obolibrary.org/obo/GO_0002523 leukocyte migration involved in inflammatory response http://purl.obolibrary.org/obo/GO_0050900 leukocyte migration The movement of a leukocyte within or between different tissues and organs of the body contributing to an inflammatory response. http://purl.obolibrary.org/obo/CL_4052013 externa theca cell http://purl.obolibrary.org/obo/CL_0000503 theca cell A specialized theca cell that forms the outer layer of the theca surrounding the ovarian follicle, appearing at the antral follicle. Originating from progenitor theca cells, theca externa cell is characterized by its fibroblast-like appearance and primarily function to provide structural support to the developing follicle. This cell produces collagen fibers and extracellular matrix components such as Col1a1 and Col1a2. http://purl.obolibrary.org/obo/GO_0002526 acute inflammatory response http://purl.obolibrary.org/obo/GO_0006954 inflammatory response Inflammation which comprises a rapid, short-lived, relatively uniform response to acute injury or antigenic challenge and is characterized by accumulations of fluid, plasma proteins, and granulocytic leukocytes. An acute inflammatory response occurs within a matter of minutes or hours, and either resolves within a few days or becomes a chronic inflammatory response. http://purl.obolibrary.org/obo/CL_4052014 pancreatic islet capillary endothelial cell http://purl.obolibrary.org/obo/CL_0002144 capillary endothelial cell A capillary endothelial cell that is part of islet of Langerhans, characterized by a high density of fenestrations —approximately ten times greater than those in exocrine pancreatic capillaries. These fenestrations facilitate efficient hormone exchange, which is essential for maintaining glucose homeostasis. The cell's structure and function are regulated by the local production of vascular endothelial growth factor-A (VEGF-A), which maintains its fenestrated architecture. http://purl.obolibrary.org/obo/GO_0002528 regulation of vascular permeability involved in acute inflammatory response http://purl.obolibrary.org/obo/GO_0043114 regulation of vascular permeability Any process that modulates the extent to which blood vessels can be pervaded by fluid contributing to an acute inflammatory response. http://purl.obolibrary.org/obo/CL_4052015 endocrine gland capillary endothelial cell http://purl.obolibrary.org/obo/CL_0002144 capillary endothelial cell Any capillary endothelial cell that is part of an endocrine gland. http://purl.obolibrary.org/obo/GO_0002532 production of molecular mediator involved in inflammatory response http://purl.obolibrary.org/obo/GO_0032501 multicellular organismal process The synthesis or release of any molecular mediator of the inflammatory response following an inflammatory stimulus, resulting in an increase in its intracellular or extracellular levels. http://purl.obolibrary.org/obo/CL_4052016 pituitary gland capillary endothelial cell http://purl.obolibrary.org/obo/CL_2000044 brain microvascular endothelial cell A capillary endothelial cell that is part of the pituitary gland. This cell is characterized by its fenestrated structure which facilitates the efficient transport of hormones and other signaling molecules, essential for endocrine signalling. http://purl.obolibrary.org/obo/GO_0002534 cytokine production involved in inflammatory response http://purl.obolibrary.org/obo/GO_0002532 production of molecular mediator involved in inflammatory response The synthesis or release of a cytokine following a inflammatory stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels. http://purl.obolibrary.org/obo/CL_4052017 choroid plexus capillary endothelial cell http://purl.obolibrary.org/obo/CL_2000044 brain microvascular endothelial cell A capillary endothelial cell that is part of the choroid plexus, characterized by its fenestrated nature with 60 to 80 nm fenestrations and lack of tight junctions. This fenestrated structure allows for the rapid delivery of water and other components, aiding in the production of cerebrospinal fluid (CSF). http://purl.obolibrary.org/obo/GO_0002536 respiratory burst involved in inflammatory response http://purl.obolibrary.org/obo/GO_0002679 respiratory burst involved in defense response A phase of elevated metabolic activity, during which oxygen consumption increases following a stimulus as part of an inflammatory response; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals, resulting in an increase in their intracellular or extracellular levels. http://purl.obolibrary.org/obo/CL_4052018 fallopian tube epithelial cell http://purl.obolibrary.org/obo/CL_0000066 epithelial cell Any epithelial cell that is part of the fallopian tube. http://purl.obolibrary.org/obo/GO_0002537 nitric oxide production involved in inflammatory response http://purl.obolibrary.org/obo/GO_0002532 production of molecular mediator involved in inflammatory response The synthesis or release of nitric oxide following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels. http://purl.obolibrary.org/obo/CL_4052019 fallopian tube non-ciliated epithelial cell http://purl.obolibrary.org/obo/CL_4052018 fallopian tube epithelial cell Any epithelial cell that is part of the fallopian tube and lacks cilia. http://purl.obolibrary.org/obo/GO_0002538 arachidonate metabolite production involved in inflammatory response http://purl.obolibrary.org/obo/GO_0002532 production of molecular mediator involved in inflammatory response The synthesis or release of products of arachidonic acid metabolism following a stimulus as part of an inflammatory response, resulting in an increase in their intracellular or extracellular levels. http://purl.obolibrary.org/obo/CL_4052020 lung resident granzyme K-associated CD8 T cell http://purl.obolibrary.org/obo/CL_4033040 lung resident memory CD8-positive, CD103-positive, alpha-beta T cell A granzyme K-associated CD8 T cell that resides in the lung, characterized by the expression of granzyme K (GZMK), and tissue residency markers CD103 and CD49a. This cell exhibits cytotoxic potential through its expression of multiple granzymes (GZMA, GZMB, GZMH, GZMM) in addition to GZMK. http://purl.obolibrary.org/obo/GO_0002539 prostaglandin production involved in inflammatory response http://purl.obolibrary.org/obo/GO_0002538 arachidonate metabolite production involved in inflammatory response The synthesis or release of any prostaglandin following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels. http://purl.obolibrary.org/obo/CL_4052021 granzyme K-associated CD8 T cell http://purl.obolibrary.org/obo/CL_0000909 CD8-positive, alpha-beta memory T cell A CD8 T cell characterized by high expression of Granzyme K (GZMK). This cell is enriched in both inflamed tissues, such as synovial tissue in rheumatoid arthritis and respiratory tissues during COVID-19, as well as non-inflamed tissues like the gut and kidneys. Unlike highly cytotoxic GZMB+ CD8+ T cell, GZMK+ CD8+ T cell exhibits lower direct cytotoxic potential, and is involved in producing pro-inflammatory cytokines such as IFN-γ and TNF-α. http://purl.obolibrary.org/obo/GO_0002540 leukotriene production involved in inflammatory response http://purl.obolibrary.org/obo/GO_0002538 arachidonate metabolite production involved in inflammatory response The synthesis or release of any leukotriene following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels. http://purl.obolibrary.org/obo/CL_4052022 fallopian tube smooth muscle cell http://purl.obolibrary.org/obo/CL_0000192 smooth muscle cell A smooth muscle cell that is part of the fallopian tube. This cell is responsible for peristaltic contractions that facilitate gamete and embryo transport, fluid mixing, and embryo admission to the uterus. http://purl.obolibrary.org/obo/GO_0002544 chronic inflammatory response http://purl.obolibrary.org/obo/GO_0006954 inflammatory response Inflammation of prolonged duration (weeks or months) in which active inflammation, tissue destruction, and attempts at repair are proceeding simultaneously. Although it may follow acute inflammation, chronic inflammation frequently begins insidiously, as a low-grade, smoldering, often asymptomatic response. http://purl.obolibrary.org/obo/CL_4052023 luminal endometrial unciliated epithelial cell http://purl.obolibrary.org/obo/CL_4052050 luminal epithelial cell of endometrium An epithelial cell that is part of the endometrial luminal epithelium, forming a continuous layer lining the uterine cavity. This cell undergoes cyclical changes during the menstrual cycle, proliferating under estrogen in the proliferative phase, and differentiating under progesterone in the secretory phase to prepare for potential implantation. During the window of implantation, this cell changes from a tall columnar shape to a shorter columnar or cuboidal form, loses polarity, and becomes receptive to blastocyst implantation. http://purl.obolibrary.org/obo/GO_0002548 monocyte chemotaxis http://purl.obolibrary.org/obo/GO_0097529 myeloid leukocyte migration The movement of a monocyte in response to an external stimulus. http://purl.obolibrary.org/obo/CL_4052024 myotendinous junction nucleus http://purl.obolibrary.org/obo/GO_0005634 nucleus A specialized muscle nucleus that is part of an extrafusal muscle fiber and overlaps the muscle-tendon junction, where muscle fibers connect to tendons. Characterized by a distinct transcriptional profile with the expression of genes like COL22A1, this myonucleus supports the structural integrity and function of the junction, playing a key role in transmitting the force generated by muscle contraction to the tendon. http://purl.obolibrary.org/obo/GO_0002551 mast cell chemotaxis http://purl.obolibrary.org/obo/GO_0097531 mast cell migration The movement of a mast cell in response to an external stimulus. http://purl.obolibrary.org/obo/CL_4052025 neuromuscular junction nucleus http://purl.obolibrary.org/obo/GO_0005634 nucleus A specialized muscle nucleus that is part of an extrafusal muscle fiber, clustered at the postsynaptic side of the neuromuscular junction. This nucleus exhibits a distinct transcriptional profile, including acetylcholine receptor (AChR) subunit genes. It regulates the production of proteins essential for maintaining the structure and function of the neuromuscular junction, supporting efficient nerve-muscle signaling for muscle contraction. http://purl.obolibrary.org/obo/GO_0002552 serotonin secretion by mast cell http://purl.obolibrary.org/obo/GO_0140029 exocytic process The regulated release of serotonin by a mast cell or group of mast cells. http://purl.obolibrary.org/obo/CL_4052026 type IIx muscle cell http://purl.obolibrary.org/obo/CL_0002212 type II muscle cell A fast type II muscle cell that is part of the skeletal muscle tissue. This cell is characterized by its intermediate metabolic profile, utilizing both glycolytic and oxidative pathways for energy production. In humans, it is distinguished by the expression of myosin heavy chain 1 (MYH1). http://purl.obolibrary.org/obo/GO_0002553 histamine secretion by mast cell http://purl.obolibrary.org/obo/GO_0140029 exocytic process The regulated release of histamine by a mast cell or group of mast cells. http://purl.obolibrary.org/obo/CL_4052027 atretic theca cell http://purl.obolibrary.org/obo/CL_4033089 atretic follicular cell of ovary A theca cell undergoing atresia, characterized by distinct morphological changes including hypertrophy, altered cell shape, and disrupted layered organization. This cell exhibits reduced steroidogenic capacity and changes in surrounding vascularization. The onset of theca cell atresia can vary, occurring at different stages of follicle atresia depending on the phase of folliculogenesis. http://purl.obolibrary.org/obo/GO_0002554 serotonin secretion by platelet http://purl.obolibrary.org/obo/GO_0140029 exocytic process The regulated release of serotonin by a platelet or group of platelets. http://purl.obolibrary.org/obo/CL_4052028 uterine natural killer cell http://purl.obolibrary.org/obo/CL_0000623 natural killer cell A natural killer cell that is part of the uterus, specifically within the endometrium during the non-pregnant state and in the decidua during pregnancy. This cell exhibits dynamic changes in frequency throughout the menstrual cycle, with lower levels during menstruation and a significant increase during the mid-secretory phase and early pregnancy. http://purl.obolibrary.org/obo/GO_0002555 histamine secretion by platelet http://purl.obolibrary.org/obo/GO_0140029 exocytic process The regulated release of histamine by a platelet or group of platelets. http://purl.obolibrary.org/obo/CL_4052029 subpleural fibroblast http://purl.obolibrary.org/obo/CL_0002553 fibroblast of lung A fibroblast that is located beneath the visceral pleura of the lung. This cell contributes to the development of idiopathic pulmonary fibrosis (IPF) by forming fibrotic lesions that originate subpleurally and extend into lung tissue through activation, proliferation, migration, and differentiation into a myofibroblast. http://purl.obolibrary.org/obo/GO_0002556 serotonin secretion by basophil http://purl.obolibrary.org/obo/GO_0140029 exocytic process The regulated release of serotonin by a basophil or group of basophils. http://purl.obolibrary.org/obo/CL_4052030 adventitial fibroblast http://purl.obolibrary.org/obo/CL_0002503 adventitial cell A fibroblast of the adventitia of a blood vessel. This cell contributes to vascular homeostasis, remodeling, and inflammation by producing extracellular matrix components, cytokines, and growth factors. Adventitial fibroblast can transition into an activated state during injury or disease, marked by increased proliferation, migration, matrix deposition, and contractile protein expression http://purl.obolibrary.org/obo/GO_0002557 histamine secretion by basophil http://purl.obolibrary.org/obo/GO_0140029 exocytic process The regulated release of histamine by a basophil or group of basophils. http://purl.obolibrary.org/obo/CL_4052031 respiratory airway secretory cell http://purl.obolibrary.org/obo/CL_0008055 respiratory tract secretory epithelial cell A secretory epithelial cell of the respiratory and terminal bronchioles. http://purl.obolibrary.org/obo/GO_0002560 basophil mediated immunity http://purl.obolibrary.org/obo/GO_0002444 myeloid leukocyte mediated immunity Any process involved in the carrying out of an immune response by a basophil. http://purl.obolibrary.org/obo/GO_7770025 intestinal type D enteroendocrine cell differentiation http://purl.obolibrary.org/obo/GO_0061101 neuroendocrine cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features of an intestinal type D enteroendocrine cell. Intestinal type D enteroendocrine cells are found in the gastrointestinal tract and in the pancreas and secrete somatostatin. http://purl.obolibrary.org/obo/GO_0002561 basophil degranulation http://purl.obolibrary.org/obo/GO_0043299 leukocyte degranulation The regulated exocytosis of secretory granules containing preformed mediators such as histamine, serotonin, and neutral proteases by a basophil. http://purl.obolibrary.org/obo/GO_7770019 negative regulation of enteroendocrine cell differentiation http://purl.obolibrary.org/obo/GO_0030857 negative regulation of epithelial cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of enteroendocrine cell differentiation. http://purl.obolibrary.org/obo/GO_0002562 somatic diversification of immune receptors via germline recombination within a single locus http://purl.obolibrary.org/obo/GO_0016444 somatic cell DNA recombination The process in which immune receptor genes are diversified through recombination of the germline genetic elements within a single genetic locus. http://purl.obolibrary.org/obo/GO_7770020 intestinal enterochromaffin enteroendocrine cell differentiation http://purl.obolibrary.org/obo/GO_0061101 neuroendocrine cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features of an intestinal enterochromaffin enteroendocrine cell. Enterochromaffin enteroendocrine cells are found in the gastrointestinal mucosa and secrete serotonin and some neurotransmitters including enkephalins and substance P. http://purl.obolibrary.org/obo/GO_0002566 somatic diversification of immune receptors via somatic mutation http://purl.obolibrary.org/obo/GO_0002200 somatic diversification of immune receptors The process in which immune receptor genes are diversified through somatic mutation. http://purl.obolibrary.org/obo/GO_7770021 intestinal type G enteroendocrine cell differentiation http://purl.obolibrary.org/obo/GO_0061101 neuroendocrine cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features of an intestinal type G enteroendocrine cell. Intestinal type G enteroendocrine cells are found in the stomach and duodenum and are responsible for the secretion of gastrin and enkephalin. http://purl.obolibrary.org/obo/GO_0002572 pro-T cell differentiation http://purl.obolibrary.org/obo/GO_0002320 lymphoid progenitor cell differentiation The process in which a precursor cell type acquires the specialized features of a pro-T cell. Pro-T cells are the earliest stage of the T cell lineage but are not fully committed. http://purl.obolibrary.org/obo/GO_7770022 intestinal type I enteroendocrine cell differentiation http://purl.obolibrary.org/obo/GO_0060575 intestinal epithelial cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features of an intestinal type I enteroendocrine cell. Intestinal type I enteroendocrine cells are found in the duodenum and jejunum and secrete cholecystokinin. http://purl.obolibrary.org/obo/GO_0002573 myeloid leukocyte differentiation http://purl.obolibrary.org/obo/GO_0030099 myeloid cell differentiation The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte lineage. http://purl.obolibrary.org/obo/GO_7770023 intestinal type L enteroendocrine cell differentiation http://purl.obolibrary.org/obo/GO_0060575 intestinal epithelial cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features of an intestinal type L enteroendocrine cell. Intestinal type L enteroendocrine cells are found in ileum and large intestine and secrete glucagon-like peptides. http://purl.obolibrary.org/obo/GO_0002574 thrombocyte differentiation http://purl.obolibrary.org/obo/GO_0030099 myeloid cell differentiation The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a thrombocyte, a nucleated cell found in all vertebrates but mammals involved in hemostasis. http://purl.obolibrary.org/obo/GO_7770024 intestinal type N enteroendocrine cell differentiation http://purl.obolibrary.org/obo/GO_0060575 intestinal epithelial cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features of an intestinal type N enteroendocrine cell. Intestinal type N enteroendocrine cells are found in the ileum and jejunum and secrete neurotensin. http://purl.obolibrary.org/obo/GO_0002575 basophil chemotaxis http://purl.obolibrary.org/obo/GO_0071621 granulocyte chemotaxis The movement of a basophil in response to an external stimulus. http://purl.obolibrary.org/obo/CL_0000941 thymic conventional dendritic cell http://purl.obolibrary.org/obo/CL_0000990 conventional dendritic cell A dendritic cell arising in thymus that has the phenotype CD11c-positive, CD11b-negative, and CD45RA-negative. http://purl.obolibrary.org/obo/GO_0002576 platelet degranulation http://purl.obolibrary.org/obo/GO_0045055 regulated exocytosis The regulated exocytosis of secretory granules containing preformed mediators such as histamine and serotonin by a platelet. http://purl.obolibrary.org/obo/UBERON_0000002 uterine cervix http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure Lower, narrow portion of the uterus where it joins with the top end of the vagina. http://purl.obolibrary.org/obo/GO_0002577 regulation of antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002682 regulation of immune system process Any process that modulates the frequency, rate, or extent of antigen processing and presentation. http://purl.obolibrary.org/obo/UBERON_0000004 nose http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure The olfactory organ of vertebrates, consisting of nares, olfactory epithelia and the structures and skeletal framework of the nasal cavity. http://purl.obolibrary.org/obo/GO_0002578 negative regulation of antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002683 negative regulation of immune system process Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation. http://purl.obolibrary.org/obo/UBERON_0000017 exocrine pancreas http://purl.obolibrary.org/obo/UBERON_0013765 digestive system element The part of the pancreas that is part of the exocrine system and which produces and store zymogens of digestive enzymes, such as chymotrypsinogen and trypsinogen in the acinar cells [GO]. http://purl.obolibrary.org/obo/GO_0002579 positive regulation of antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002684 positive regulation of immune system process Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation. http://purl.obolibrary.org/obo/UBERON_0000021 cutaneous appendage http://purl.obolibrary.org/obo/UBERON_0013703 integumentary projection Anatomical projection that protrudes from the skin. Examples: hair, nail, feather, claw, hoof, horn, wattle, spur, beak, antler, bristle and some scales. http://purl.obolibrary.org/obo/GO_0002580 regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II http://purl.obolibrary.org/obo/GO_0002577 regulation of antigen processing and presentation Any process that modulates the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II. http://purl.obolibrary.org/obo/UBERON_0000033 head http://purl.obolibrary.org/obo/UBERON_0011676 subdivision of organism along main body axis The head is the anterior-most division of the body [GO]. http://purl.obolibrary.org/obo/GO_0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II http://purl.obolibrary.org/obo/GO_0002580 regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II. http://purl.obolibrary.org/obo/UBERON_0000057 urethra http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure The fibromuscular tubular canal through which urine is discharged from the bladder to the exterior via the external urinary meatus; in males, the urethra is joined by the ejaculatory ducts and serves as a passageway for semen during ejaculation, as well as a canal for urine during voiding; in females, the urethra is shorter and emerges above the vaginal opening. http://purl.obolibrary.org/obo/GO_0002582 positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II http://purl.obolibrary.org/obo/GO_0002580 regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II. http://purl.obolibrary.org/obo/UBERON_0000079 male reproductive system http://purl.obolibrary.org/obo/UBERON_0000990 reproductive system The organs associated with producing offspring in the gender that produces spermatozoa. http://purl.obolibrary.org/obo/GO_0002583 regulation of antigen processing and presentation of peptide antigen http://purl.obolibrary.org/obo/GO_0002577 regulation of antigen processing and presentation Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen. http://purl.obolibrary.org/obo/UBERON_0000304 tendon sheath http://purl.obolibrary.org/obo/UBERON_0004923 organ component layer A layer of membrane around a tendon. It has 2 layers: synovial sheath + fibrous tendon sheath. http://purl.obolibrary.org/obo/GO_0002584 negative regulation of antigen processing and presentation of peptide antigen http://purl.obolibrary.org/obo/GO_0002583 regulation of antigen processing and presentation of peptide antigen Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of peptide antigen. http://purl.obolibrary.org/obo/UBERON_0000382 apocrine sweat gland http://purl.obolibrary.org/obo/UBERON_0012177 skin apocrine gland Apocrine sweat glands are sweat glands composed of a coiled secretory portion located at the junction of the dermis and subcutaneous fat, from which a straight portion inserts and secretes into the infundibular portion of the hair follicle. The ducts of apocrine glands open into the canals of hair follicles. The stimulus for the secretion of apocrine sweat glands is adrenaline, which is a hormone carried in the blood[WP]. http://purl.obolibrary.org/obo/GO_0002585 positive regulation of antigen processing and presentation of peptide antigen http://purl.obolibrary.org/obo/GO_0002583 regulation of antigen processing and presentation of peptide antigen Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of peptide antigen. http://purl.obolibrary.org/obo/UBERON_0000391 leptomeninx http://purl.obolibrary.org/obo/UBERON_0002360 meninx Pia mater or arachnoid mater. http://purl.obolibrary.org/obo/GO_0002586 regulation of antigen processing and presentation of peptide antigen via MHC class II http://purl.obolibrary.org/obo/GO_0002583 regulation of antigen processing and presentation of peptide antigen Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class II. http://purl.obolibrary.org/obo/UBERON_0000402 nasal vestibule http://purl.obolibrary.org/obo/UBERON_0002553 anatomical cavity The nasal vestibule is the most anterior part of the nasal cavity. It's enclosed by the cartilages of nose and lined by the same epithelium of the skin. The other part of the nasal cavity, which is lined by the respiratory epithelium, is called nasal cavity proper. [WP,unvetted]. http://purl.obolibrary.org/obo/GO_0002587 negative regulation of antigen processing and presentation of peptide antigen via MHC class II http://purl.obolibrary.org/obo/GO_0002586 regulation of antigen processing and presentation of peptide antigen via MHC class II Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class II. http://purl.obolibrary.org/obo/UBERON_0000403 scalp http://purl.obolibrary.org/obo/UBERON_0034921 multi organ part structure The outer covering of the calvaria. It is composed of several layers: SKIN; subcutaneous connective tissue; the occipitofrontal muscle which includes the tendonous galea aponeurotica; Loose connective tissue; and the pericranium (the PERIOSTEUM of the SKULL). http://purl.obolibrary.org/obo/GO_0002588 positive regulation of antigen processing and presentation of peptide antigen via MHC class II http://purl.obolibrary.org/obo/GO_0002586 regulation of antigen processing and presentation of peptide antigen via MHC class II Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class II. http://purl.obolibrary.org/obo/UBERON_0000423 eccrine sweat gland http://purl.obolibrary.org/obo/UBERON_0010243 merocrine gland A merocrine, unbranched, unbranched, coiled, tubular gland sweat gland. In humans, distributed over almost all of the body surface, and promote cooling by evaporation of their secretion. http://purl.obolibrary.org/obo/GO_0002589 regulation of antigen processing and presentation of peptide antigen via MHC class I http://purl.obolibrary.org/obo/GO_0002583 regulation of antigen processing and presentation of peptide antigen Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class I. http://purl.obolibrary.org/obo/UBERON_0000458 endocervix http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure The region of the opening of the uterine cervix into the uterine cavity. http://purl.obolibrary.org/obo/GO_0002590 negative regulation of antigen processing and presentation of peptide antigen via MHC class I http://purl.obolibrary.org/obo/GO_0002589 regulation of antigen processing and presentation of peptide antigen via MHC class I Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class I. http://purl.obolibrary.org/obo/UBERON_0000473 testis http://purl.obolibrary.org/obo/UBERON_0003135 male reproductive organ A gonad of a male animal. A gonad produces and releases sperm. http://purl.obolibrary.org/obo/GO_0002591 positive regulation of antigen processing and presentation of peptide antigen via MHC class I http://purl.obolibrary.org/obo/GO_0002589 regulation of antigen processing and presentation of peptide antigen via MHC class I Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class I. http://purl.obolibrary.org/obo/UBERON_0000474 female reproductive system http://purl.obolibrary.org/obo/UBERON_0000990 reproductive system The organs and associated structures associated with bearing offspring in a female animal. http://purl.obolibrary.org/obo/GO_0002604 regulation of dendritic cell antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002577 regulation of antigen processing and presentation Any process that modulates the frequency, rate, or extent of dendritic cell antigen processing and presentation. http://purl.obolibrary.org/obo/UBERON_0000915 thoracic segment of trunk http://purl.obolibrary.org/obo/UBERON_0011676 subdivision of organism along main body axis Subdivision of trunk that lies between the head and the abdomen. http://purl.obolibrary.org/obo/GO_0002605 negative regulation of dendritic cell antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002604 regulation of dendritic cell antigen processing and presentation Any process that stops, prevents, or reduces the frequency, rate, or extent of dendritic cell antigen processing and presentation. http://purl.obolibrary.org/obo/UBERON_0000946 cardiac valve http://purl.obolibrary.org/obo/UBERON_0010313 neural crest-derived structure A membranous fold of the heart that prevents reflux of fluid. http://purl.obolibrary.org/obo/GO_0002606 positive regulation of dendritic cell antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002604 regulation of dendritic cell antigen processing and presentation Any process that activates or increases the frequency, rate, or extent of dendritic cell antigen processing and presentation. http://purl.obolibrary.org/obo/UBERON_0000947 aorta http://purl.obolibrary.org/obo/UBERON_0013768 great vessel of heart The main trunk of the systemic arterial system that carries blood from the heart to all the organs and other structures of the body, bringing oxygenated blood to all parts of the body in the systemic circulation. http://purl.obolibrary.org/obo/GO_0002607 regulation of myeloid dendritic cell antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002604 regulation of dendritic cell antigen processing and presentation Any process that modulates the frequency, rate, or extent of myeloid dendritic cell antigen processing and presentation. http://purl.obolibrary.org/obo/UBERON_0000959 optic chiasma http://purl.obolibrary.org/obo/UBERON_0007425 decussation of diencephalon A decussation of the diencephalon where the fibers of the optic nerve cross. http://purl.obolibrary.org/obo/GO_0002608 negative regulation of myeloid dendritic cell antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002607 regulation of myeloid dendritic cell antigen processing and presentation Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid dendritic cell antigen processing and presentation. http://purl.obolibrary.org/obo/UBERON_0000974 neck http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision An organism subdivision that extends from the head to the pectoral girdle, encompassing the cervical vertebral column. http://purl.obolibrary.org/obo/GO_0002609 positive regulation of myeloid dendritic cell antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002607 regulation of myeloid dendritic cell antigen processing and presentation Any process that activates or increases the frequency, rate, or extent of myeloid dendritic cell antigen processing and presentation. http://purl.obolibrary.org/obo/UBERON_0000975 sternum http://purl.obolibrary.org/obo/UBERON_0010363 endochondral element A midventral endochondral skeletal element which represents the origin site of the pectoral muscles[PHENOSCAPE:ad]. http://purl.obolibrary.org/obo/GO_0002610 regulation of plasmacytoid dendritic cell antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002604 regulation of dendritic cell antigen processing and presentation Any process that modulates the frequency, rate, or extent of plasmacytoid dendritic cell antigen processing and presentation. http://purl.obolibrary.org/obo/UBERON_0000991 gonad http://purl.obolibrary.org/obo/UBERON_0003133 reproductive organ Reproductive organ that produces and releases eggs (ovary) or sperm (testis). http://purl.obolibrary.org/obo/GO_0002611 negative regulation of plasmacytoid dendritic cell antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002610 regulation of plasmacytoid dendritic cell antigen processing and presentation Any process that stops, prevents, or reduces the frequency, rate, or extent of plasmacytoid dendritic cell antigen processing and presentation. http://purl.obolibrary.org/obo/UBERON_0001003 skin epidermis http://purl.obolibrary.org/obo/UBERON_3000961 external integument structure The outer epithelial layer of the skin that is superficial to the dermis. http://purl.obolibrary.org/obo/GO_0002612 positive regulation of plasmacytoid dendritic cell antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002610 regulation of plasmacytoid dendritic cell antigen processing and presentation Any process that activates or increases the frequency, rate, or extent of plasmacytoid dendritic cell antigen processing and presentation. http://purl.obolibrary.org/obo/UBERON_0001007 digestive system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system Anatomical system that has as its parts the organs devoted to the ingestion, digestion, and assimilation of food and the discharge of residual wastes. http://purl.obolibrary.org/obo/GO_0002613 regulation of monocyte antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002577 regulation of antigen processing and presentation Any process that modulates the frequency, rate, or extent of monocyte antigen processing and presentation. http://purl.obolibrary.org/obo/UBERON_0001008 renal system http://purl.obolibrary.org/obo/UBERON_8450002 excretory system The renal system in an anatomical system that maintains fluid balance and contributes to electrolyte balance, acid/base balance, and disposal of nitrogenous waste products. http://purl.obolibrary.org/obo/GO_0002614 negative regulation of monocyte antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002613 regulation of monocyte antigen processing and presentation Any process that stops, prevents, or reduces the frequency, rate, or extent of monocyte antigen processing and presentation. http://purl.obolibrary.org/obo/UBERON_0001037 strand of hair http://purl.obolibrary.org/obo/UBERON_0000021 cutaneous appendage A filament, mostly protein, that grows from follicles found in the dermis[WP]. http://purl.obolibrary.org/obo/GO_0002615 positive regulation of monocyte antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002613 regulation of monocyte antigen processing and presentation Any process that activates or increases the frequency, rate, or extent of monocyte antigen processing and presentation. http://purl.obolibrary.org/obo/UBERON_0001135 smooth muscle tissue http://purl.obolibrary.org/obo/UBERON_0002385 muscle tissue Muscle tissue which is unstriated, composed primarily of smooth muscle fibers surrounded by a reticulum of collagen and elastic fibers. Smooth muscle differs from striated muscle in the much higher actin/myosin ratio, the absence of conspicuous sarcomeres and the ability to contract to a much smaller fraction of its resting length[GO]. http://purl.obolibrary.org/obo/GO_0002616 regulation of macrophage antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002577 regulation of antigen processing and presentation Any process that modulates the frequency, rate, or extent of macrophage antigen processing and presentation. http://purl.obolibrary.org/obo/UBERON_0001156 ascending colon http://purl.obolibrary.org/obo/UBERON_0000168 proximal-distal subdivision of colon Section of colon which is distal to the cecum and proximal to the transversecolon.[FMA,modified]. http://purl.obolibrary.org/obo/GO_0002617 negative regulation of macrophage antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002616 regulation of macrophage antigen processing and presentation Any process that stops, prevents, or reduces the frequency, rate, or extent of macrophage antigen processing and presentation. http://purl.obolibrary.org/obo/UBERON_0001157 transverse colon http://purl.obolibrary.org/obo/UBERON_0000168 proximal-distal subdivision of colon The proximal-distal subdivision of colon that runs transversely across the upper part of the abdomen, from the right to the left colic flexure. Continuous with the descending colon[BTO,modified]. http://purl.obolibrary.org/obo/GO_0002618 positive regulation of macrophage antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002616 regulation of macrophage antigen processing and presentation Any process that activates or increases the frequency, rate, or extent of macrophage antigen processing and presentation. http://purl.obolibrary.org/obo/UBERON_0001161 body of stomach http://purl.obolibrary.org/obo/UBERON_0009870 zone of stomach The body of stomach is the part of the stomach that lies between the fundus above and the pyloric antrum below; its boundaries are poorly defined[GO]. http://purl.obolibrary.org/obo/GO_0002622 regulation of B cell antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002712 regulation of B cell mediated immunity Any process that modulates the frequency, rate, or extent of B cell antigen processing and presentation. http://purl.obolibrary.org/obo/GO_0002623 negative regulation of B cell antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002713 negative regulation of B cell mediated immunity Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell antigen processing and presentation. http://purl.obolibrary.org/obo/UBERON_0001173 biliary tree http://purl.obolibrary.org/obo/UBERON_0013765 digestive system element A complex network of conduits that begins with the canals of Hering (intralobar bile duct) and progressively merges into a system of interlobular, septal, and major ducts which then coalesce to form the extrahepatic bile ducts, which finally deliver bile to the intestine, and in some species to the gallbladder. http://purl.obolibrary.org/obo/GO_0002624 positive regulation of B cell antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002622 regulation of B cell antigen processing and presentation Any process that activates or increases the frequency, rate, or extent of B cell antigen processing and presentation. http://purl.obolibrary.org/obo/UBERON_0001174 common bile duct http://purl.obolibrary.org/obo/UBERON_0003703 extrahepatic bile duct The part of the biliary tree formed by the union of the cystic duct and the common hepatic duct. http://purl.obolibrary.org/obo/GO_0002625 regulation of T cell antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002709 regulation of T cell mediated immunity Any process that modulates the frequency, rate, or extent of T cell antigen processing and presentation. http://purl.obolibrary.org/obo/UBERON_0001182 superior mesenteric artery http://purl.obolibrary.org/obo/UBERON_0005616 mesenteric artery Mesenteric artery that supplies the whole length of the small intestine except the superior part of the duodenum. It also supplies the cecum and the ascending part of the colon and about half the transverse part of the colon. It arises from the anterior surface of the aorta below the celiac artery at the level of the first lumbar vertebra. http://purl.obolibrary.org/obo/GO_0002626 negative regulation of T cell antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002710 negative regulation of T cell mediated immunity Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell antigen processing and presentation. http://purl.obolibrary.org/obo/UBERON_0001224 renal pelvis http://purl.obolibrary.org/obo/UBERON_0004111 anatomical conduit A funnel shaped proximal portion of the ureter that is formed by convergence of the major calices [MP]. http://purl.obolibrary.org/obo/GO_0002627 positive regulation of T cell antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002711 positive regulation of T cell mediated immunity Any process that activates or increases the frequency, rate, or extent of T cell antigen processing and presentation. http://purl.obolibrary.org/obo/UBERON_0001232 collecting duct of renal tubule http://purl.obolibrary.org/obo/UBERON_0006555 excretory tube The collecting duct is a portion of the nephron through which water flows, moving passively down its concentration gradient. http://purl.obolibrary.org/obo/GO_0002628 regulation of proteolysis associated with antigen processing and presentation http://purl.obolibrary.org/obo/GO_0030162 regulation of proteolysis Any process that modulates the frequency, rate, or extent of proteolysis associated with antigen processing and presentation. http://purl.obolibrary.org/obo/UBERON_0001235 adrenal cortex http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure The thick outer layer of the adrenal gland that produces and secretes steroid hormones such as corticosterone, estrone and aldosterone. http://purl.obolibrary.org/obo/GO_0002629 negative regulation of proteolysis associated with antigen processing and presentation http://purl.obolibrary.org/obo/GO_0045861 negative regulation of proteolysis Any process that stops, prevents, or reduces the frequency, rate, or extent of proteolysis associated with antigen processing and presentation. http://purl.obolibrary.org/obo/UBERON_0001236 adrenal medulla http://purl.obolibrary.org/obo/UBERON_0010313 neural crest-derived structure The inner portion of the adrenal gland that consists mainly of chromaffin cells which produce, store and secrete neurotransmitters such as epinephrine and norepinephrine. http://purl.obolibrary.org/obo/UBERON_0001264 pancreas http://purl.obolibrary.org/obo/UBERON_0002075 viscus An endoderm derived structure that produces precursors of digestive enzymes and blood glucose regulating hormones[GO]. http://purl.obolibrary.org/obo/GO_0002630 positive regulation of proteolysis associated with antigen processing and presentation http://purl.obolibrary.org/obo/GO_0045862 positive regulation of proteolysis Any process that activates or increases the frequency, rate, or extent of proteolysis associated with antigen processing and presentation. http://purl.obolibrary.org/obo/UBERON_0001296 myometrium http://purl.obolibrary.org/obo/UBERON_0034933 layer of smooth muscle tissue The smooth muscle coat of the uterus, which forms the main mass of the organ and surrounds and supports the endometrium. http://purl.obolibrary.org/obo/GO_0002631 regulation of granuloma formation http://purl.obolibrary.org/obo/GO_0002697 regulation of immune effector process Any process that modulates the frequency, rate, or extent of granuloma formation. http://purl.obolibrary.org/obo/GO_0002632 negative regulation of granuloma formation http://purl.obolibrary.org/obo/GO_0002698 negative regulation of immune effector process Any process that stops, prevents, or reduces the frequency, rate, or extent of granuloma formation. http://purl.obolibrary.org/obo/UBERON_0001456 face http://purl.obolibrary.org/obo/UBERON_0001444 subdivision of head A subdivision of the head that has as parts the layers deep to the surface of the anterior surface, including the mouth, eyes, and nose (when present). In vertebrates, this includes the facial skeleton and structures superficial to the facial skeleton (cheeks, mouth, eyeballs, skin of face, etc). http://purl.obolibrary.org/obo/UBERON_0001557 upper respiratory tract http://purl.obolibrary.org/obo/UBERON_0000072 proximo-distal subdivision of respiratory tract The segment of the respiratory tract that starts proximally with the nose and ends distally with the cricoid cartilage, before continuing to the trachea. http://purl.obolibrary.org/obo/UBERON_0001579 olfactory nerve http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure Nerve that carries information from the olfactory epithelium to the olfactory bulb[Butler and Hodos]. http://purl.obolibrary.org/obo/GO_0002633 positive regulation of granuloma formation http://purl.obolibrary.org/obo/GO_0002699 positive regulation of immune effector process Any process that activates or increases the frequency, rate, or extent of granuloma formation. http://purl.obolibrary.org/obo/UBERON_0001585 anterior vena cava http://purl.obolibrary.org/obo/UBERON_0004087 vena cava A vein that carries deoxygenated blood from the upper half of the body into the right atrium of the heart. http://purl.obolibrary.org/obo/GO_0002634 regulation of germinal center formation http://purl.obolibrary.org/obo/GO_0022603 regulation of anatomical structure morphogenesis Any process that modulates the frequency, rate, or extent of germinal center formation. http://purl.obolibrary.org/obo/UBERON_0001601 extra-ocular muscle http://purl.obolibrary.org/obo/UBERON_0010959 craniocervical muscle Skeletal muscle derived from cranial mesoderm and controls eye movements. http://purl.obolibrary.org/obo/UBERON_0001621 coronary artery http://purl.obolibrary.org/obo/UBERON_0004573 systemic artery An artery that supplies the myocardium. http://purl.obolibrary.org/obo/UBERON_0001638 vein http://purl.obolibrary.org/obo/UBERON_0003920 venous blood vessel Any of the tubular branching vessels that carry blood from the capillaries toward the heart. http://purl.obolibrary.org/obo/GO_0002635 negative regulation of germinal center formation http://purl.obolibrary.org/obo/GO_0051093 negative regulation of developmental process Any process that stops, prevents, or reduces the frequency, rate, or extent of germinal center formation. http://purl.obolibrary.org/obo/UBERON_0001643 oculomotor nerve http://purl.obolibrary.org/obo/UBERON_0001785 cranial nerve Cranial nerve which connects the midbrain to the extra-ocular and intra-ocular muscles. http://purl.obolibrary.org/obo/UBERON_0001645 trigeminal nerve http://purl.obolibrary.org/obo/UBERON_0001785 cranial nerve Cranial nerve that has three branches - the ophthalmic (supplying the skin of the nose and upper jaw), the maxillary and the mandibular (supplying the lower jaw). http://purl.obolibrary.org/obo/GO_0002636 positive regulation of germinal center formation http://purl.obolibrary.org/obo/GO_0051094 positive regulation of developmental process Any process that activates or increases the frequency, rate, or extent of germinal center formation. http://purl.obolibrary.org/obo/UBERON_0001647 facial nerve http://purl.obolibrary.org/obo/UBERON_0010314 structure with developmental contribution from neural crest Cranial nerve that branches into the supraorbital (supplying the skin of the eye region and the lateral line organs here), the palatine (to the roof of the buccal cavity), and the hyomandibular (dividing into the jugular and mental branches). http://purl.obolibrary.org/obo/UBERON_0001649 glossopharyngeal nerve http://purl.obolibrary.org/obo/UBERON_0001785 cranial nerve Cranial nerve that branches into the ramus communicans (to the skin), the pretrematic (to the walls of the pharynx and mouth, viscero-sensory fibers), and the larval post-trematic branch (lost in the adult). http://purl.obolibrary.org/obo/GO_0002637 regulation of immunoglobulin production http://purl.obolibrary.org/obo/GO_0002700 regulation of production of molecular mediator of immune response Any process that modulates the frequency, rate, or extent of immunoglobulin production. http://purl.obolibrary.org/obo/UBERON_0001679 ethmoid bone http://purl.obolibrary.org/obo/UBERON_0011164 neurocranium bone A bone in the skull that separates the nasal cavity from the brain. As such, it is located at the roof of the nose, between the two orbits. The cubical bone is lightweight due to a spongy construction. The ethmoid bone is one of the bones that makes up the orbit of the eye[WP]. http://purl.obolibrary.org/obo/GO_0002638 negative regulation of immunoglobulin production http://purl.obolibrary.org/obo/GO_0002701 negative regulation of production of molecular mediator of immune response Any process that stops, prevents, or reduces the frequency, rate, or extent of immunoglobulin production. http://purl.obolibrary.org/obo/UBERON_0001691 external ear http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure Part of the ear external to the tympanum (eardrum). It typically consists of a tube (the external auditory meatus) that directs sound waves on to the tympanum, and may also include the external pinna, which extends beyond the skull[GO]. http://purl.obolibrary.org/obo/UBERON_0001728 nasopharynx http://purl.obolibrary.org/obo/UBERON_0000072 proximo-distal subdivision of respiratory tract The section of the pharynx that lies above the soft palate. http://purl.obolibrary.org/obo/GO_0002639 positive regulation of immunoglobulin production http://purl.obolibrary.org/obo/GO_0002702 positive regulation of production of molecular mediator of immune response Any process that activates or increases the frequency, rate, or extent of immunoglobulin production. http://purl.obolibrary.org/obo/UBERON_0001735 tonsillar ring http://purl.obolibrary.org/obo/UBERON_0001962 gut-associated lymphoid tissue The circular lymphoid tissue formed by the lingual, pharyngeal, and faucial tonsils. http://purl.obolibrary.org/obo/UBERON_0001754 dental pulp http://purl.obolibrary.org/obo/UBERON_0011825 loose connective tissue The part in the center of a tooth made up of living soft tissue and cells called odontoblasts[WP]. http://purl.obolibrary.org/obo/UBERON_0001757 pinna http://purl.obolibrary.org/obo/UBERON_0001444 subdivision of head The part of the ear that projects from the head, connecting to the external acoustic meatus. http://purl.obolibrary.org/obo/UBERON_0001768 uvea http://purl.obolibrary.org/obo/UBERON_0010314 structure with developmental contribution from neural crest The pigmented middle of the three concentric layers that make up an eye, consisting of the iris, ciliary body and choroid[WP,edited]. http://purl.obolibrary.org/obo/GO_0002643 regulation of tolerance induction http://purl.obolibrary.org/obo/GO_0002682 regulation of immune system process Any process that modulates the frequency, rate, or extent of tolerance induction. http://purl.obolibrary.org/obo/UBERON_0001769 iris http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure The adjustable membrane, composed of the stroma and pigmented epithelium, located just in front of the crystalline lens within the eye. http://purl.obolibrary.org/obo/GO_0002644 negative regulation of tolerance induction http://purl.obolibrary.org/obo/GO_0051241 negative regulation of multicellular organismal process Any process that stops, prevents, or reduces the frequency, rate, or extent of tolerance induction. http://purl.obolibrary.org/obo/UBERON_0001775 ciliary body http://purl.obolibrary.org/obo/UBERON_0010314 structure with developmental contribution from neural crest The thickened portion of the vascular tunic, which lies between the choroid and the iris, composed of ciliary muscle and ciliary processes. http://purl.obolibrary.org/obo/GO_0002645 positive regulation of tolerance induction http://purl.obolibrary.org/obo/GO_0051240 positive regulation of multicellular organismal process Any process that activates or increases the frequency, rate, or extent of tolerance induction. http://purl.obolibrary.org/obo/UBERON_0001785 cranial nerve http://purl.obolibrary.org/obo/UBERON_0034713 cranial neuron projection bundle Cranial nerves are nerves that emerge directly from the brain, in contrast to spinal nerves, which emerge from segments of the spinal cord. http://purl.obolibrary.org/obo/GO_0002652 regulation of tolerance induction dependent upon immune response http://purl.obolibrary.org/obo/GO_0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains Any process that modulates the frequency, rate, or extent of tolerance induction dependent upon immune response. http://purl.obolibrary.org/obo/UBERON_0001797 vitreous humor http://purl.obolibrary.org/obo/UBERON_0006312 ocular refractive media A transparent, semigelatinous substance that fills the cavity behind the crystalline lens of the eye and in front of the retina. http://purl.obolibrary.org/obo/GO_0002653 negative regulation of tolerance induction dependent upon immune response http://purl.obolibrary.org/obo/GO_0002823 negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains Any process that stops, prevents, or reduces the frequency, rate, or extent of tolerance induction dependent upon immune response. http://purl.obolibrary.org/obo/UBERON_0001814 brachial nerve plexus http://purl.obolibrary.org/obo/UBERON_0001813 spinal nerve plexus An arrangement of nerve fibers, running from the spine where it proceeds through the neck then the axilla and into the arm where it innervates skin and muscle. [WP,modified]. http://purl.obolibrary.org/obo/GO_0002654 positive regulation of tolerance induction dependent upon immune response http://purl.obolibrary.org/obo/GO_0002824 positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains Any process that activates or increases the frequency, rate, or extent of tolerance induction dependent upon immune response. http://purl.obolibrary.org/obo/UBERON_0001817 lacrimal gland http://purl.obolibrary.org/obo/UBERON_0015154 lateral gland of orbital region The lacrimal glands are paired almond-shaped glands, located in or near the orbital region, that secrete the aqueous layer of the tear film.[WP]. http://purl.obolibrary.org/obo/GO_0002655 regulation of tolerance induction to nonself antigen http://purl.obolibrary.org/obo/GO_0002652 regulation of tolerance induction dependent upon immune response Any process that modulates the frequency, rate, or extent of tolerance induction to nonself antigen. http://purl.obolibrary.org/obo/UBERON_0001821 sebaceous gland http://purl.obolibrary.org/obo/UBERON_0019319 exocrine gland of integumental system A holocrine gland that secretes sebum into the hair follicles, or in hairless areas into ducts.[MP]. http://purl.obolibrary.org/obo/GO_0002656 negative regulation of tolerance induction to nonself antigen http://purl.obolibrary.org/obo/GO_0002655 regulation of tolerance induction to nonself antigen Any process that stops, prevents, or reduces the frequency, rate, or extent of tolerance induction to nonself antigen. http://purl.obolibrary.org/obo/UBERON_0001828 gingiva http://purl.obolibrary.org/obo/UBERON_0003729 mouth mucosa The fibrous investing tissue, covered by keratinized epithelium, that immediately surrounds a tooth and is contiguous with its periodontal ligament and with the mucosal tissues of the mouth[Glossary of Periodontal Terms 2001]. http://purl.obolibrary.org/obo/GO_0002657 positive regulation of tolerance induction to nonself antigen http://purl.obolibrary.org/obo/GO_0002655 regulation of tolerance induction to nonself antigen Any process that activates or increases the frequency, rate, or extent of tolerance induction to nonself antigen. http://purl.obolibrary.org/obo/UBERON_0001832 sublingual gland http://purl.obolibrary.org/obo/UBERON_0001829 major salivary gland The small mucin-producing salivary glands in the floor of the mouth beneath the tongue, anterior to the submandibular gland. http://purl.obolibrary.org/obo/UBERON_0001834 upper lip http://purl.obolibrary.org/obo/UBERON_0001833 lip Lip that covers the upper portion of the mouth.[TAO]. http://purl.obolibrary.org/obo/GO_0002658 regulation of peripheral tolerance induction http://purl.obolibrary.org/obo/GO_0002652 regulation of tolerance induction dependent upon immune response Any process that modulates the frequency, rate, or extent of peripheral tolerance induction. http://purl.obolibrary.org/obo/UBERON_0001835 lower lip http://purl.obolibrary.org/obo/UBERON_0001833 lip Lip that covers the lower portion of the mouth.[TAO]. http://purl.obolibrary.org/obo/GO_0002659 negative regulation of peripheral tolerance induction http://purl.obolibrary.org/obo/GO_0002658 regulation of peripheral tolerance induction Any process that stops, prevents, or reduces the frequency, rate, or extent of peripheral tolerance induction. http://purl.obolibrary.org/obo/UBERON_0001846 internal ear http://purl.obolibrary.org/obo/UBERON_0034921 multi organ part structure Complex labyrinthine structure that comprises sensory endorgans specialized for vestibular, auditory, and acoustico-vestibular sensation. http://purl.obolibrary.org/obo/GO_0002660 positive regulation of peripheral tolerance induction http://purl.obolibrary.org/obo/GO_0002658 regulation of peripheral tolerance induction Any process that activates or increases the frequency, rate, or extent of peripheral tolerance induction. http://purl.obolibrary.org/obo/UBERON_0001869 cerebral hemisphere http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure One of two bilateral, largely symmetrical organ subdivisions within the telencephalon which contain the cerebral cortex and cerebral white matter.[FMA]. http://purl.obolibrary.org/obo/GO_0002661 regulation of B cell tolerance induction http://purl.obolibrary.org/obo/GO_0002643 regulation of tolerance induction Any process that modulates the frequency, rate, or extent of B cell tolerance induction. http://purl.obolibrary.org/obo/UBERON_0001871 temporal lobe http://purl.obolibrary.org/obo/UBERON_0016526 lobe of cerebral hemisphere Lower lateral part of the cerebral hemisphere. (MSH). http://purl.obolibrary.org/obo/UBERON_0001886 choroid plexus http://purl.obolibrary.org/obo/UBERON_0036303 vasculature of central nervous system A network formed by blood vessels and the tela choroidea which secretes CSF into the ventricular spaces. http://purl.obolibrary.org/obo/UBERON_0001893 telencephalon http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure Part of the forebrain consisting of paired olfactory bulbs and cerebral hemispheres. http://purl.obolibrary.org/obo/UBERON_0001894 diencephalon http://purl.obolibrary.org/obo/UBERON_0010314 structure with developmental contribution from neural crest The division of the forebrain that develops from the foremost primary cerebral vesicle. http://purl.obolibrary.org/obo/GO_0002662 negative regulation of B cell tolerance induction http://purl.obolibrary.org/obo/GO_0002661 regulation of B cell tolerance induction Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell tolerance induction. http://purl.obolibrary.org/obo/UBERON_0001905 pineal body http://purl.obolibrary.org/obo/UBERON_0010134 secretory circumventricular organ A midline, cone like structure located in the dorso-caudal roof of the 3rd ventricle, attached by peduncles to the habenular and posterior commissures. The stalk contains nerve fibers, blood vessels, connective tissue and parenchymal cells (Paxinos, The Rat Central Nervous System, 2nd ed, pg 399). http://purl.obolibrary.org/obo/GO_0002663 positive regulation of B cell tolerance induction http://purl.obolibrary.org/obo/GO_0002661 regulation of B cell tolerance induction Any process that activates or increases the frequency, rate, or extent of B cell tolerance induction. http://purl.obolibrary.org/obo/UBERON_0001908 optic tract http://purl.obolibrary.org/obo/UBERON_0011591 tract of diencephalon Diencephalic white matter (tract) which is comprised of retinal ganglion cell axons after which they have passed through the optic chiasm[ZFA]. Predominantly white matter structure found in diencephalon consisting of fibers originating in the retina. The optic tract is considered to extend from the point of the optic chiasm and terminates largely, although not exclusively, in the lateral geniculate complex. Other fibers end in the superior colliculus and other structures in the diencephalon, midbrain and brainstem (MM)[NIF]. http://purl.obolibrary.org/obo/GO_0002664 regulation of T cell tolerance induction http://purl.obolibrary.org/obo/GO_0002643 regulation of tolerance induction Any process that modulates the frequency, rate, or extent of T cell tolerance induction. http://purl.obolibrary.org/obo/UBERON_0001987 placenta http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure Organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin[GO]. The fetal portion of the placenta is known as the villous chorion. The maternal portion is known as the decidua basalis. The two portions are held together by anchoring villi that are anchored to the decidua basalis by the cytotrophoblastic shell. http://purl.obolibrary.org/obo/UBERON_0002016 pulmonary vein http://purl.obolibrary.org/obo/UBERON_0013768 great vessel of heart Pulmonary veins are blood vessels that transport blood from the lungs to the heart[GO]. http://purl.obolibrary.org/obo/GO_0002665 negative regulation of T cell tolerance induction http://purl.obolibrary.org/obo/GO_0002664 regulation of T cell tolerance induction Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell tolerance induction. http://purl.obolibrary.org/obo/UBERON_0002019 accessory XI nerve http://purl.obolibrary.org/obo/UBERON_0035642 laryngeal nerve A cranial nerve that originates from neurons in the medulla and in the cervical spinal cord. http://purl.obolibrary.org/obo/UBERON_0002030 nipple http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure Projection of skin containing the outlets for 15-20 lactiferous ducts arranged cylindrically around the tip. http://purl.obolibrary.org/obo/GO_0002666 positive regulation of T cell tolerance induction http://purl.obolibrary.org/obo/GO_0002664 regulation of T cell tolerance induction Any process that activates or increases the frequency, rate, or extent of T cell tolerance induction. http://purl.obolibrary.org/obo/UBERON_0002037 cerebellum http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain Part of the metencephalon that lies in the posterior cranial fossa behind the brain stem. It is concerned with the coordination of movement[MESH]. A large dorsally projecting part of the brain concerned especially with the coordination of muscles and the maintenance of bodily equilibrium, situated between the brain stem and the back of the cerebrum , and formed in humans of two lateral lobes and a median lobe[BTO]. Brain structure derived from the anterior hindbrain, and perhaps including posterior midbrain. The cerebellum plays a role in somatic motor function, the control of muscle tone, and balance[ZFA]. http://purl.obolibrary.org/obo/UBERON_0002067 dermis http://purl.obolibrary.org/obo/UBERON_0013754 integumentary system layer The dermis is a layer of skin between the epidermis (with which it makes up the skin) and subcutaneous tissues, and is composed of two layers, the papillary and reticular dermis[WP]. http://purl.obolibrary.org/obo/GO_0002667 regulation of T cell anergy http://purl.obolibrary.org/obo/GO_0002911 regulation of lymphocyte anergy Any process that modulates the frequency, rate, or extent of T cell anergy. http://purl.obolibrary.org/obo/UBERON_0002198 neurohypophysis http://purl.obolibrary.org/obo/UBERON_0010134 secretory circumventricular organ The posterior part of the pituitary gland that secretes hormones involved in blood pressure regulation such as oxytocin and antidiuretic hormon. http://purl.obolibrary.org/obo/UBERON_0002285 telencephalic ventricle http://purl.obolibrary.org/obo/UBERON_0004086 brain ventricle A brain ventricle that is part of a telencephalon. In mammals and species with an evaginated telencephalon, this is one of a pair of lateral structures, one in each hemisphere. http://purl.obolibrary.org/obo/UBERON_0002286 third ventricle http://purl.obolibrary.org/obo/UBERON_0004086 brain ventricle Part of the ventricular system of the brain, forming a single large cavity in the midline of the diencephalon; it is continuous with the lateral ventricles through the interventricular foramen and the fourth ventricle through the cerebral aqueduct. (Maryann Martone). http://purl.obolibrary.org/obo/GO_0002668 negative regulation of T cell anergy http://purl.obolibrary.org/obo/GO_0002912 negative regulation of lymphocyte anergy Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell anergy. http://purl.obolibrary.org/obo/UBERON_0002348 epicardium http://purl.obolibrary.org/obo/UBERON_0000481 multi-tissue structure A region of the serous membrane that forms the innermost layer of the pericardium and the outer surface of the heart. http://purl.obolibrary.org/obo/GO_0002669 positive regulation of T cell anergy http://purl.obolibrary.org/obo/GO_0002913 positive regulation of lymphocyte anergy Any process that activates or increases the frequency, rate, or extent of T cell anergy. http://purl.obolibrary.org/obo/UBERON_0002349 myocardium http://purl.obolibrary.org/obo/UBERON_0018260 layer of muscle tissue The middle layer of the heart, comprised mainly of striated cardiac muscle fibers. http://purl.obolibrary.org/obo/UBERON_0002364 tympanic membrane http://purl.obolibrary.org/obo/UBERON_0000094 membrane organ A thin membrane that separates the external ear from the middle ear, consisting of two epithelia (one part of the the external accoustic meatus epithelium, the other part of the tympanic cavity epithelium) with a fibrous layer between them. Its function is to transmit sound from the air to the ossicles inside the middle ear. The malleus bone bridges the gap between the eardrum and the other ossicles. Rupture or perforation of the eardrum can lead to conductive hearing loss. [WP,unvetted]. http://purl.obolibrary.org/obo/UBERON_0002369 adrenal gland http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure Either of a pair of complex endocrine organs near the anterior medial border of the kidney consisting of a mesodermal cortex that produces glucocorticoid, mineralocorticoid, and androgenic hormones and an ectodermal medulla that produces epinephrine and norepinephrine[BTO]. http://purl.obolibrary.org/obo/UBERON_0002371 bone marrow http://purl.obolibrary.org/obo/UBERON_0000479 tissue The soft tissue that fills the cavities of bones. http://purl.obolibrary.org/obo/GO_0002670 regulation of B cell anergy http://purl.obolibrary.org/obo/GO_0002911 regulation of lymphocyte anergy Any process that modulates the frequency, rate, or extent of B cell anergy. http://purl.obolibrary.org/obo/UBERON_0002385 muscle tissue http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure Muscle tissue is a contractile tissue made up of actin and myosin fibers[GO]. http://purl.obolibrary.org/obo/GO_0002671 negative regulation of B cell anergy http://purl.obolibrary.org/obo/GO_0002912 negative regulation of lymphocyte anergy Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell anergy. http://purl.obolibrary.org/obo/UBERON_0002386 forelimb zeugopod http://purl.obolibrary.org/obo/UBERON_0008785 upper limb segment The middle limb segment of the pectoral free limb, between the autopod and stylopod segments. Includes as parts the forelimb zeugopodial skeleton, which includes as parts the radius and ulna, or their cartilage precursors, or evolutionary variants. http://purl.obolibrary.org/obo/GO_0002672 positive regulation of B cell anergy http://purl.obolibrary.org/obo/GO_0002913 positive regulation of lymphocyte anergy Any process that activates or increases the frequency, rate, or extent of B cell anergy. http://purl.obolibrary.org/obo/UBERON_0002390 hematopoietic system http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure Anatomical system that is involved in the production of hematopoietic cells. http://purl.obolibrary.org/obo/GO_0002673 regulation of acute inflammatory response http://purl.obolibrary.org/obo/GO_0050727 regulation of inflammatory response Any process that modulates the frequency, rate, or extent of an acute inflammatory response. http://purl.obolibrary.org/obo/UBERON_0002411 clitoris http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure The small, erectile body located at the anterior end of the vulva. http://purl.obolibrary.org/obo/GO_0002674 negative regulation of acute inflammatory response http://purl.obolibrary.org/obo/GO_0050728 negative regulation of inflammatory response Any process that stops, prevents, or reduces the frequency, rate, or extent of an acute inflammatory response. http://purl.obolibrary.org/obo/UBERON_0002420 basal ganglion http://purl.obolibrary.org/obo/UBERON_0007245 nuclear complex of neuraxis An individual member of a collection of basal ganglia. Basal ganglia are subcortical masses of gray matter in the forebrain and midbrain that are richly interconnected and so viewed as a functional system. The nuclei usually included are the caudate nucleus (caudoputamen in rodents), putamen, globus pallidus, substantia nigra (pars compacta and pars reticulata) and the subthalamic nucleus. Some also include the nucleus accumbens and ventral pallidum[NIF,modified]. http://purl.obolibrary.org/obo/GO_0002675 positive regulation of acute inflammatory response http://purl.obolibrary.org/obo/GO_0050729 positive regulation of inflammatory response Any process that activates or increases the frequency, rate, or extent of an acute inflammatory response. http://purl.obolibrary.org/obo/UBERON_0002495 long bone http://purl.obolibrary.org/obo/UBERON_0001474 bone element A long bone is a bone that has a shaft and 2 ends and is longer than it is wide. Long bones have a thick outside layer of compact bone and an inner medullary cavity containing bone marrow. The ends of a long bone contain spongy bone and an epiphyseal plate or line depending on the stage of development. The epiphyseal plate is a hyaline cartilage, where new bone growth takes place, lengthening the bone prior to adulthood. Bone lengthening ceases when this cartilage is lost, leaving a remnant referred to as an epiphyseal line. http://purl.obolibrary.org/obo/GO_0002676 regulation of chronic inflammatory response http://purl.obolibrary.org/obo/GO_0050727 regulation of inflammatory response Any process that modulates the frequency, rate, or extent of a chronic inflammatory response. http://purl.obolibrary.org/obo/UBERON_0003074 mesonephric duct http://purl.obolibrary.org/obo/UBERON_0009201 nephric duct Paired organ that connects the primitive kidney Wolffian body (or mesonephros) to the cloaca and serves as the anlage for certain male reproductive organs. the Wolffian duct is what remains of the pronephric duct after the atrophy of the pronephros[WP]. In Zebrafish: Duct of the adult kidney (mesonephros), present bilaterally ventral to the somites and leading to the cloacal chamber[ZFA]. http://purl.obolibrary.org/obo/GO_0002677 negative regulation of chronic inflammatory response http://purl.obolibrary.org/obo/GO_0050728 negative regulation of inflammatory response Any process that stops, prevents, or reduces the frequency, rate, or extent of a chronic inflammatory response. http://purl.obolibrary.org/obo/UBERON_0003129 skull http://purl.obolibrary.org/obo/UBERON_0000075 subdivision of skeletal system Anatomical structure that is part of the head consisting entirely of cranium and mandible[WP]. http://purl.obolibrary.org/obo/GO_0002678 positive regulation of chronic inflammatory response http://purl.obolibrary.org/obo/GO_0050729 positive regulation of inflammatory response Any process that activates or increases the frequency, rate, or extent of a chronic inflammatory response. http://purl.obolibrary.org/obo/UBERON_0003292 meninx of spinal cord http://purl.obolibrary.org/obo/UBERON_0005174 dorsal region element A meninx that is part of a spinal cord [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0002679 respiratory burst involved in defense response http://purl.obolibrary.org/obo/GO_0045730 respiratory burst A phase of elevated metabolic activity, during which oxygen consumption increases made as part of a defense response ; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals. http://purl.obolibrary.org/obo/UBERON_0003687 foramen magnum http://purl.obolibrary.org/obo/UBERON_0013685 foramen of skull In anatomy, in the occipital bone, the foramen magnum is one of the several oval or circular apertures in the base of the skull, through which the medulla oblongata (an extension of the spinal cord) enters and exits the skull vault. Apart from the transmission of the medulla oblongata and its membranes, the foramen magnum transmits the Spinal Accessory nerve, vertebral arteries, the anterior and posterior spinal arteries, the membrana tectoria and alar ligaments. [WP,unvetted]. http://purl.obolibrary.org/obo/GO_0002682 regulation of immune system process http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process Any process that modulates the frequency, rate, or extent of an immune system process. http://purl.obolibrary.org/obo/UBERON_0003704 intrahepatic bile duct http://purl.obolibrary.org/obo/UBERON_0002394 bile duct Passages within the liver for the conveyance of bile. Includes right and left hepatic ducts even though these may join outside the liver to form the common hepatic duct. http://purl.obolibrary.org/obo/UBERON_0003712 cavernous sinus http://purl.obolibrary.org/obo/UBERON_0005486 venous dural sinus The cavernous sinus (or lateral sellar compartment), within the human head, is a large collection of thin-walled veins creating a cavity bordered by the temporal bone of the skull and the sphenoid bone, lateral to the sella turcica. http://purl.obolibrary.org/obo/GO_0002683 negative regulation of immune system process http://purl.obolibrary.org/obo/GO_0048519 negative regulation of biological process Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune system process. http://purl.obolibrary.org/obo/UBERON_0004086 brain ventricle http://purl.obolibrary.org/obo/UBERON_0005358 ventricle of nervous system One of the system of communicating cavities in the brain that are continuous with the central canal of the spinal cord, that like it are derived from the medullary canal of the embryo, that are lined with an epithelial ependyma, and that contain a serous fluid. http://purl.obolibrary.org/obo/GO_0002684 positive regulation of immune system process http://purl.obolibrary.org/obo/GO_0048518 positive regulation of biological process Any process that activates or increases the frequency, rate, or extent of an immune system process. http://purl.obolibrary.org/obo/UBERON_0004363 pharyngeal arch artery http://purl.obolibrary.org/obo/UBERON_0010314 structure with developmental contribution from neural crest One of a series of paired embryological vascular structures formed within a pharyngeal arch; in the adult, some of these vessels give rise to the great vessels[MP]. http://purl.obolibrary.org/obo/GO_0002685 regulation of leukocyte migration http://purl.obolibrary.org/obo/GO_0030334 regulation of cell migration Any process that modulates the frequency, rate, or extent of leukocyte migration. http://purl.obolibrary.org/obo/UBERON_0004681 vestibular system http://purl.obolibrary.org/obo/UBERON_0001032 sensory system The sensory system for the sense of balance. http://purl.obolibrary.org/obo/GO_0002686 negative regulation of leukocyte migration http://purl.obolibrary.org/obo/GO_0030336 negative regulation of cell migration Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte migration. http://purl.obolibrary.org/obo/UBERON_0004720 cerebellar vermis http://purl.obolibrary.org/obo/UBERON_0002749 regional part of cerebellar cortex A subregion of the cerebellar cortex, consisting of the most medial zone of the cerebellar cortex, stradding the midline. May be continuous with the lateral cerebellar hemispheres in some areas of the cerebellum, e.g., dorsally, or separated by deeper fissures in others (e.g., ventrally). http://purl.obolibrary.org/obo/GO_0002687 positive regulation of leukocyte migration http://purl.obolibrary.org/obo/GO_0030335 positive regulation of cell migration Any process that activates or increases the frequency, rate, or extent of leukocyte migration. http://purl.obolibrary.org/obo/UBERON_0005396 carotid artery segment http://purl.obolibrary.org/obo/UBERON_0004573 systemic artery One of: the common carotid artery, or its branches, the external and internal carotid arteries. http://purl.obolibrary.org/obo/GO_0002688 regulation of leukocyte chemotaxis http://purl.obolibrary.org/obo/GO_0050920 regulation of chemotaxis Any process that modulates the frequency, rate, or extent of leukocyte chemotaxis. http://purl.obolibrary.org/obo/UBERON_0005456 jugular foramen http://purl.obolibrary.org/obo/UBERON_0018321 foramen for glossopharyngeal nerve The jugular foramen is a large aperture in the base of the skull. It is located behind the carotid canal and is formed in front by the petrous portion of the temporal, and behind by the occipital; it is generally larger on the right than on the left side. http://purl.obolibrary.org/obo/GO_0002689 negative regulation of leukocyte chemotaxis http://purl.obolibrary.org/obo/GO_0050922 negative regulation of chemotaxis Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte chemotaxis. http://purl.obolibrary.org/obo/UBERON_0007329 pancreatic duct http://purl.obolibrary.org/obo/UBERON_0004119 endoderm-derived structure A duct that collects and carries secretions of the exocrine pancreas to the intestine. http://purl.obolibrary.org/obo/GO_0002690 positive regulation of leukocyte chemotaxis http://purl.obolibrary.org/obo/GO_0050921 positive regulation of chemotaxis Any process that activates or increases the frequency, rate, or extent of leukocyte chemotaxis. http://purl.obolibrary.org/obo/UBERON_0007616 layer of synovial tissue http://purl.obolibrary.org/obo/UBERON_0000042 serous membrane A thin, loose vascular connective tissue that makes up the membranes surrounding joints and the sheaths protecting tendons (particularly flexor tendons in the hands and feet) where they pass over bony prominences. Synovial tissue contains synovial cells, which secrete a viscous liquid called synovial fluid; this liquid contains protein and hyaluronic acid and serves as a lubricant and nutrient for the joint cartilage surfaces[BTO]. Synovial tissue can be found in tendons (tissues that connect muscle to bone), bursae (fluid-filled, cushioning sacs found in spaces between tendons, ligaments, and bones), and the cavity (hollow enclosed area) that separates the bones of a freely movable joint, such as the knee or elbow[BTO]. http://purl.obolibrary.org/obo/GO_0002694 regulation of leukocyte activation http://purl.obolibrary.org/obo/GO_0050865 regulation of cell activation Any process that modulates the frequency, rate, or extent of leukocyte activation. http://purl.obolibrary.org/obo/UBERON_0007798 vascular system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system Anatomical system that consists of all blood and lymph vessels. http://purl.obolibrary.org/obo/GO_0002695 negative regulation of leukocyte activation http://purl.obolibrary.org/obo/GO_0050866 negative regulation of cell activation Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte activation. http://purl.obolibrary.org/obo/UBERON_0008883 osteoid http://purl.obolibrary.org/obo/UBERON_0002481 bone tissue Bone tissue that is an unmineralized bone matrix deposited by osteoblasts prior to the mineralization of bone tissue. http://purl.obolibrary.org/obo/GO_0002696 positive regulation of leukocyte activation http://purl.obolibrary.org/obo/GO_0050867 positive regulation of cell activation Any process that activates or increases the frequency, rate, or extent of leukocyte activation. http://purl.obolibrary.org/obo/UBERON_0008974 apocrine gland http://purl.obolibrary.org/obo/UBERON_0002365 exocrine gland Any exocrine gland whose cells bud their secretions off through the plasma membrane producing membrane-bound vesicles in the lumen; the apical portion of the secretory cell of the gland pinches off and enters the lumen; it loses part of its cytoplasm in their secretions; apocrine secretion is functional during hormonal stress or puberty; an example of true apocrine glands are mammary glands, responsible for secreting breast milk. http://purl.obolibrary.org/obo/GO_0002697 regulation of immune effector process http://purl.obolibrary.org/obo/GO_0002682 regulation of immune system process Any process that modulates the frequency, rate, or extent of an immune effector process. http://purl.obolibrary.org/obo/UBERON_0010743 meningeal cluster http://purl.obolibrary.org/obo/UBERON_0034925 anatomical collection The collection of all meningeal layers that line a central nervous system. http://purl.obolibrary.org/obo/GO_0002698 negative regulation of immune effector process http://purl.obolibrary.org/obo/GO_0002697 regulation of immune effector process Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune effector process. http://purl.obolibrary.org/obo/UBERON_0010996 articular cartilage of joint http://purl.obolibrary.org/obo/UBERON_0001994 hyaline cartilage tissue A thin layer of cartilage, usually hyaline, on the articular surface of bones in synovial joints. http://purl.obolibrary.org/obo/GO_0002699 positive regulation of immune effector process http://purl.obolibrary.org/obo/GO_0002697 regulation of immune effector process Any process that activates or increases the frequency, rate, or extent of an immune effector process. http://purl.obolibrary.org/obo/UBERON_0016490 auditory system http://purl.obolibrary.org/obo/UBERON_0007037 mechanosensory system Is the sensory system for the sense of hearing. http://purl.obolibrary.org/obo/GO_0002700 regulation of production of molecular mediator of immune response http://purl.obolibrary.org/obo/GO_0010468 regulation of gene expression Any process that modulates the frequency, rate, or extent of the production of molecular mediator of immune response. http://purl.obolibrary.org/obo/UBERON_0018707 bladder organ http://purl.obolibrary.org/obo/UBERON_0009856 sac A membranous sac in animals that serves as the receptacle of a liquid or contains gas. http://purl.obolibrary.org/obo/GO_0002701 negative regulation of production of molecular mediator of immune response http://purl.obolibrary.org/obo/GO_0002700 regulation of production of molecular mediator of immune response Any process that stops, prevents, or reduces the frequency, rate, or extent of the production of molecular mediator of immune response. http://purl.obolibrary.org/obo/IAO_0000078 curation status specification http://purl.obolibrary.org/obo/IAO_0000102 data about an ontology part The curation status of the term. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value. http://purl.obolibrary.org/obo/GO_0002702 positive regulation of production of molecular mediator of immune response http://purl.obolibrary.org/obo/GO_0010628 positive regulation of gene expression Any process that activates or increases the frequency, rate, or extent of the production of molecular mediator of immune response. http://purl.obolibrary.org/obo/IAO_0000102 data about an ontology part http://purl.obolibrary.org/obo/IAO_0000027 data entity Data about an ontology part is a data item about a part of an ontology, for example a term http://purl.obolibrary.org/obo/GO_0002703 regulation of leukocyte mediated immunity http://purl.obolibrary.org/obo/GO_0002697 regulation of immune effector process Any process that modulates the frequency, rate, or extent of leukocyte mediated immunity. http://purl.obolibrary.org/obo/IAO_0000225 obsolescence reason specification http://purl.obolibrary.org/obo/IAO_0000102 data about an ontology part The reason for which a term has been deprecated. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value. http://purl.obolibrary.org/obo/IAO_0000409 denotator type http://purl.obolibrary.org/obo/IAO_0000102 data about an ontology part A denotator type indicates how a term should be interpreted from an ontological perspective. http://purl.obolibrary.org/obo/GO_0002704 negative regulation of leukocyte mediated immunity http://purl.obolibrary.org/obo/GO_0002703 regulation of leukocyte mediated immunity Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte mediated immunity. http://purl.obolibrary.org/obo/PATO_0001374 ploidy http://purl.obolibrary.org/obo/PATO_0001396 cellular quality A cellular quality inhering in a bearer by virtue of the bearer's number of homologous sets of chromosomes in the nucleus or primary chromosome-containing compartment of the cell, each set essentially coding for all the biological traits of the organism. http://purl.obolibrary.org/obo/GO_0002705 positive regulation of leukocyte mediated immunity http://purl.obolibrary.org/obo/GO_0002703 regulation of leukocyte mediated immunity Any process that activates or increases the frequency, rate, or extent of leukocyte mediated immunity. http://purl.obolibrary.org/obo/PATO_0001375 haploid http://purl.obolibrary.org/obo/PATO_0001393 euploid A ploidy quality inhering in a bearer by virtue of the bearer's containing a single set of homologous chromosomes. http://purl.obolibrary.org/obo/GO_0002706 regulation of lymphocyte mediated immunity http://purl.obolibrary.org/obo/GO_0002703 regulation of leukocyte mediated immunity Any process that modulates the frequency, rate, or extent of lymphocyte mediated immunity. http://purl.obolibrary.org/obo/PATO_0001377 polyploid http://purl.obolibrary.org/obo/PATO_0001393 euploid A ploidy quality inhering in a bearer by virtue of the bearer's containing more than two homologous sets of chromosomes. http://purl.obolibrary.org/obo/GO_0002707 negative regulation of lymphocyte mediated immunity http://purl.obolibrary.org/obo/GO_0002706 regulation of lymphocyte mediated immunity Any process that stops, prevents, or reduces the frequency, rate, or extent of lymphocyte mediated immunity. http://purl.obolibrary.org/obo/PATO_0001394 diploid http://purl.obolibrary.org/obo/PATO_0001393 euploid A ploidy quality inhering in a bearer by virtue of the bearer's having two copies (homologs) of each chromosome, usually one from the mother and one from the father. http://purl.obolibrary.org/obo/PATO_0001396 cellular quality http://purl.obolibrary.org/obo/PATO_0070044 anatomical structure quality A monadic quality of continuant that exists at the cellular level of organisation. http://purl.obolibrary.org/obo/GO_0002708 positive regulation of lymphocyte mediated immunity http://purl.obolibrary.org/obo/GO_0002706 regulation of lymphocyte mediated immunity Any process that activates or increases the frequency, rate, or extent of lymphocyte mediated immunity. http://purl.obolibrary.org/obo/PATO_0001546 quality of a solid http://purl.obolibrary.org/obo/PATO_0002198 quality of a substance A physical quality inhering in a bearer by virtue of the bearer's exhibiting the physical characteristics of an entity characterized by particles arranged such that their shape and volume are relatively stable. http://purl.obolibrary.org/obo/GO_0002709 regulation of T cell mediated immunity http://purl.obolibrary.org/obo/GO_0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains Any process that modulates the frequency, rate, or extent of T cell mediated immunity. http://purl.obolibrary.org/obo/PATO_0001547 quality of a gas http://purl.obolibrary.org/obo/PATO_0002198 quality of a substance A physical quality inhering in a bearer by virtue of the bearer's exhibiting the physical characteristics of an entity consisting of particles that have neither a defined volume nor defined shape. http://purl.obolibrary.org/obo/GO_0002710 negative regulation of T cell mediated immunity http://purl.obolibrary.org/obo/GO_0002823 negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell mediated immunity. http://purl.obolibrary.org/obo/PATO_0001548 quality of a liquid http://purl.obolibrary.org/obo/PATO_0002198 quality of a substance A physical quality inhering in an entity exhibiting the physical characteristics of an amorphous (non-crystalline) form of matter between a gas and a solid that has a definite volume, but no definite shape. http://purl.obolibrary.org/obo/GO_0002711 positive regulation of T cell mediated immunity http://purl.obolibrary.org/obo/GO_0002824 positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains Any process that activates or increases the frequency, rate, or extent of T cell mediated immunity. http://purl.obolibrary.org/obo/PATO_0001995 organismal quality http://purl.obolibrary.org/obo/PATO_0001241 physical object quality A quality that inheres in an entire organism or part of an organism. http://purl.obolibrary.org/obo/GO_0002712 regulation of B cell mediated immunity http://purl.obolibrary.org/obo/GO_0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains Any process that modulates the frequency, rate, or extent of B cell mediated immunity. http://purl.obolibrary.org/obo/PR_000000001 protein http://purl.obolibrary.org/obo/PR_000018263 amino acid chain An amino acid chain that is canonically produced de novo by ribosome-mediated translation of a genetically-encoded mRNA, and any derivatives thereof. http://purl.obolibrary.org/obo/GO_0002713 negative regulation of B cell mediated immunity http://purl.obolibrary.org/obo/GO_0002823 negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell mediated immunity. http://purl.obolibrary.org/obo/PR_000001004 CD4 molecule http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CD4 gene or a 1:1 ortholog thereof. CD4 is an accessory protein for MHC class-II antigen/T-cell receptor interaction. It is the primary receptor for HIV-1. CD4 has four immunoglobulin-like domains in its extracellular region that share the same structure, but can differ in sequence. http://purl.obolibrary.org/obo/GO_0002714 positive regulation of B cell mediated immunity http://purl.obolibrary.org/obo/GO_0002824 positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains Any process that activates or increases the frequency, rate, or extent of B cell mediated immunity. http://purl.obolibrary.org/obo/PR_000001018 CD3 subunit with immunoglobulin domain http://purl.obolibrary.org/obo/PR_000000001 protein A protein that has a core domain composition consisting of an extracellular N-terminal domain that adopts an immunoglobulin fold, a transmembrane domain, and an intracellular C-terminal domain with a single copy of the Immunoreceptor tyrosine-based activation motif (Pfam:PF02189) (ITAM). It constitutes the invariant subunit of the T cell antigen receptor (TCR). TCR is a surface receptor on T cells responsible for recognizing MHC-restricted antigens and initiating the cellular immune response. http://purl.obolibrary.org/obo/GO_0002715 regulation of natural killer cell mediated immunity http://purl.obolibrary.org/obo/GO_0045088 regulation of innate immune response Any process that modulates the frequency, rate, or extent of natural killer cell mediated immunity. http://purl.obolibrary.org/obo/PR_000025402 T cell receptor co-receptor CD8 http://purl.obolibrary.org/obo/GO_0032991 protein-containing complex A protein-containing complex that is a membrane-bound heterodimeric co-receptor for MHC class-I antigen/T-cell receptor interaction. http://purl.obolibrary.org/obo/GO_0002716 negative regulation of natural killer cell mediated immunity http://purl.obolibrary.org/obo/GO_0045824 negative regulation of innate immune response Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell mediated immunity. http://purl.obolibrary.org/obo/GO_0120023 somatostatin binding http://purl.obolibrary.org/obo/GO_0017046 peptide hormone binding Binding to somatostatin, a polypeptide hormone involved in regulating pancreatic alpha and pancreatic beta cells and controlling growth hormone secretion as well as many other functions. Somatostatin is produced by several cell types including pancreatic delta cells. There are several different mature forms of somatostatin. http://purl.obolibrary.org/obo/GO_0002717 positive regulation of natural killer cell mediated immunity http://purl.obolibrary.org/obo/GO_0045089 positive regulation of innate immune response Any process that activates or increases the frequency, rate, or extent of natural killer cell mediated immunity. http://purl.obolibrary.org/obo/GO_0140014 mitotic nuclear division http://purl.obolibrary.org/obo/GO_1903047 mitotic cell cycle process A mitotic cell cycle process comprising the steps by which the nucleus of a eukaryotic cell divides; the process involves condensation of chromosomal DNA into a highly compacted form. Canonically, mitosis produces two daughter nuclei whose chromosome complement is identical to that of the mother cell. http://purl.obolibrary.org/obo/GO_0002718 regulation of cytokine production involved in immune response http://purl.obolibrary.org/obo/GO_0002700 regulation of production of molecular mediator of immune response Any process that modulates the frequency, rate, or extent of cytokine production that contributes to an immune response. http://purl.obolibrary.org/obo/GO_0120029 proton export across plasma membrane http://purl.obolibrary.org/obo/GO_0140115 export across plasma membrane The directed movement of hydrogen ions (protons) from inside a cell, across the plasma membrane and into the extracellular region. http://purl.obolibrary.org/obo/GO_0002719 negative regulation of cytokine production involved in immune response http://purl.obolibrary.org/obo/GO_0002718 regulation of cytokine production involved in immune response Any process that stops, prevents, or reduces the frequency, rate, or extent of cytokine production contributing to an immune response. http://purl.obolibrary.org/obo/CL_0001061 abnormal cell http://purl.obolibrary.org/obo/CL_0000000 cell A cell found in an organism or derived from an organism exhibiting a phenotype that deviates from the expected phenotype of any native cell type of that organism. Abnormal cells are typically found in disease states or disease models. http://purl.obolibrary.org/obo/GO_0002720 positive regulation of cytokine production involved in immune response http://purl.obolibrary.org/obo/GO_0002718 regulation of cytokine production involved in immune response Any process that activates or increases the frequency, rate, or extent of cytokine production that contributes to an immune response. http://purl.obolibrary.org/obo/CL_0001063 neoplastic cell http://purl.obolibrary.org/obo/CL_0001061 abnormal cell An abnormal cell exhibiting dysregulation of cell proliferation or programmed cell death and capable of forming a neoplasm, an aggregate of cells in the form of a tumor mass or an excess number of abnormal cells (liquid tumor) within an organism. http://purl.obolibrary.org/obo/GO_0002721 regulation of B cell cytokine production http://purl.obolibrary.org/obo/GO_0002718 regulation of cytokine production involved in immune response Any process that modulates the frequency, rate, or extent of B cell cytokine production. http://purl.obolibrary.org/obo/CL_0001064 malignant cell http://purl.obolibrary.org/obo/CL_0001063 neoplastic cell A neoplastic cell that is capable of entering a surrounding tissue http://purl.obolibrary.org/obo/GO_0002722 negative regulation of B cell cytokine production http://purl.obolibrary.org/obo/GO_0002721 regulation of B cell cytokine production Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell cytokine production. http://purl.obolibrary.org/obo/CL_0001067 group 1 innate lymphoid cell http://purl.obolibrary.org/obo/CL_0001065 innate lymphoid cell An innate lymphoid cell that is capable of producing the type 1 cytokine IFN-gamma, but not Th2 or Th17 cell-associated cytokines. http://purl.obolibrary.org/obo/GO_0002723 positive regulation of B cell cytokine production http://purl.obolibrary.org/obo/GO_0002721 regulation of B cell cytokine production Any process that activates or increases the frequency, rate, or extent of B cell cytokine production. http://purl.obolibrary.org/obo/CL_0001068 ILC1 http://purl.obolibrary.org/obo/CL_0001067 group 1 innate lymphoid cell A group 1 innate lymphoid cell that is non-cytotoxic. http://purl.obolibrary.org/obo/GO_0002724 regulation of T cell cytokine production http://purl.obolibrary.org/obo/GO_0002718 regulation of cytokine production involved in immune response Any process that modulates the frequency, rate, or extent of T cell cytokine production. http://purl.obolibrary.org/obo/CL_0001069 group 2 innate lymphoid cell http://purl.obolibrary.org/obo/CL_0001065 innate lymphoid cell An innate lymphoid cell that is capable of producing T-helper 2-cell associated cytokines upon stimulation. http://purl.obolibrary.org/obo/GO_0002725 negative regulation of T cell cytokine production http://purl.obolibrary.org/obo/GO_0002724 regulation of T cell cytokine production Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell cytokine production. http://purl.obolibrary.org/obo/CL_0001071 group 3 innate lymphoid cell http://purl.obolibrary.org/obo/CL_0001065 innate lymphoid cell An innate lymphoid cell that constituitively expresses RORgt and is capable of expressing IL17A and/or IL-22. http://purl.obolibrary.org/obo/GO_0002726 positive regulation of T cell cytokine production http://purl.obolibrary.org/obo/GO_0002724 regulation of T cell cytokine production Any process that activates or increases the frequency, rate, or extent of T cell cytokine production. http://purl.obolibrary.org/obo/GO_0120039 plasma membrane bounded cell projection morphogenesis http://purl.obolibrary.org/obo/GO_0048858 cell projection morphogenesis The process in which the anatomical structures of a plasma membrane bounded cell projection are generated and organized. http://purl.obolibrary.org/obo/GO_0002727 regulation of natural killer cell cytokine production http://purl.obolibrary.org/obo/GO_0002718 regulation of cytokine production involved in immune response Any process that modulates the frequency, rate, or extent of natural killer cell cytokine production. http://purl.obolibrary.org/obo/GO_0120036 plasma membrane bounded cell projection organization http://purl.obolibrary.org/obo/GO_0030030 cell projection organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a plasma membrane bounded prolongation or process extending from a cell, e.g. a cilium or axon. http://purl.obolibrary.org/obo/GO_0002728 negative regulation of natural killer cell cytokine production http://purl.obolibrary.org/obo/GO_0002727 regulation of natural killer cell cytokine production Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell cytokine production. http://purl.obolibrary.org/obo/GO_0062013 positive regulation of small molecule metabolic process http://purl.obolibrary.org/obo/GO_0009893 positive regulation of metabolic process Any process that activates or increases the frequency, rate or extent of a small molecule metabolic process. http://purl.obolibrary.org/obo/GO_0002729 positive regulation of natural killer cell cytokine production http://purl.obolibrary.org/obo/GO_0002727 regulation of natural killer cell cytokine production Any process that activates or increases the frequency, rate, or extent of natural killer cell cytokine production. http://purl.obolibrary.org/obo/GO_0062014 negative regulation of small molecule metabolic process http://purl.obolibrary.org/obo/GO_0009892 negative regulation of metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of a small molecule metabolic process. http://purl.obolibrary.org/obo/GO_0002730 regulation of dendritic cell cytokine production http://purl.obolibrary.org/obo/GO_0002718 regulation of cytokine production involved in immune response Any process that modulates the frequency, rate, or extent of dendritic cell cytokine production. http://purl.obolibrary.org/obo/GO_0120158 positive regulation of collagen catabolic process http://purl.obolibrary.org/obo/GO_0010714 positive regulation of collagen metabolic process Any process that activates or increases the frequency, rate or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix. http://purl.obolibrary.org/obo/GO_0002731 negative regulation of dendritic cell cytokine production http://purl.obolibrary.org/obo/GO_0002730 regulation of dendritic cell cytokine production Any process that stops, prevents, or reduces the frequency, rate, or extent of dendritic cell cytokine production. http://purl.obolibrary.org/obo/GO_0150052 regulation of postsynapse assembly http://purl.obolibrary.org/obo/GO_0051963 regulation of synapse assembly Any process that modulates the frequency, rate or extent of postsynapse assembly, the aggregation, arrangement and bonding together of a set of components to form a postsynapse. http://purl.obolibrary.org/obo/GO_0002732 positive regulation of dendritic cell cytokine production http://purl.obolibrary.org/obo/GO_0002730 regulation of dendritic cell cytokine production Any process that activates or increases the frequency, rate, or extent of dendritic cell cytokine production. http://purl.obolibrary.org/obo/GO_0140238 presynaptic endocytosis http://purl.obolibrary.org/obo/GO_0099003 vesicle-mediated transport in synapse A vesicle-mediated transport process in which the presynapse take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle. http://purl.obolibrary.org/obo/GO_0120186 negative regulation of protein localization to chromatin http://purl.obolibrary.org/obo/GO_1905634 regulation of protein localization to chromatin Any process that stops, prevents, or reduces the frequency, rate or extent of protein localization to chromatin. http://purl.obolibrary.org/obo/GO_0002733 regulation of myeloid dendritic cell cytokine production http://purl.obolibrary.org/obo/GO_0002886 regulation of myeloid leukocyte mediated immunity Any process that modulates the frequency, rate, or extent of myeloid dendritic cell cytokine production. http://purl.obolibrary.org/obo/GO_0150099 neuron-glial cell signaling http://purl.obolibrary.org/obo/GO_0007267 cell-cell signaling Cell-cell signaling that mediates the transfer of information from a neuron to a glial cell. This signaling has been shown to be mediated by various molecules released by different types of neurons, e.g. glutamate, gamma-amino butyric acid (GABA), noradrenaline, acetylcholine, dopamine and adenosine. http://purl.obolibrary.org/obo/GO_0002734 negative regulation of myeloid dendritic cell cytokine production http://purl.obolibrary.org/obo/GO_0002887 negative regulation of myeloid leukocyte mediated immunity Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid dendritic cell cytokine production. http://purl.obolibrary.org/obo/PR_000044649 calcium-activated potassium channel protein http://purl.obolibrary.org/obo/PR_000044651 calcium- and sodium-activated potassium channel protein A potassium channel protein that is activated by calcium. A calcium-activated potassium channel enables the calcium concentration-regulatable energy-independent passage of potassium ions across a lipid bilayer down a concentration gradient. http://purl.obolibrary.org/obo/PR_000044657 transient receptor potential channel protein http://purl.obolibrary.org/obo/PR_000044628 voltage-gated ion channel protein A voltage-gated ion channel protein that is a translation product of the human TRPC1, TRPM1, TRPV1, TRPA1, TRPP1 or TRPML1 gene, paralogs thereof, 1:1 orthologs thereof, a semi-ortholog thereof, or pro-orthologs thereof. http://purl.obolibrary.org/obo/PR_000044672 aquaporin protein http://purl.obolibrary.org/obo/PR_000044676 channel protein A channel protein that has water channel activity. A water channel enables facilitated diffusion of water (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. http://purl.obolibrary.org/obo/PR_000044682 piezo channel protein http://purl.obolibrary.org/obo/PR_000049983 ion channel protein An ion channel protein that is a translation product of the human PIEZO1 or PIEZO2 genes, 1:1 orthologs thereof, or a semi-ortholog thereof. http://purl.obolibrary.org/obo/PR_A0A0B4J238 T cell receptor alpha variable 1-2 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A protein that is a translation product of the TRAV1-2 gene in human. http://purl.obolibrary.org/obo/GO_0002735 positive regulation of myeloid dendritic cell cytokine production http://purl.obolibrary.org/obo/GO_0061081 positive regulation of myeloid leukocyte cytokine production involved in immune response Any process that activates or increases the frequency, rate, or extent of myeloid dendritic cell cytokine production. http://purl.obolibrary.org/obo/CL_4023087 fan Martinotti neuron http://purl.obolibrary.org/obo/CL_4023076 Martinotti neuron A Martinotti neuron that has axons that form a fan-like plexus. http://purl.obolibrary.org/obo/GO_0002736 regulation of plasmacytoid dendritic cell cytokine production http://purl.obolibrary.org/obo/GO_0002730 regulation of dendritic cell cytokine production Any process that modulates the frequency, rate, or extent of plasmacytoid dendritic cell cytokine production. http://purl.obolibrary.org/obo/CL_4030004 thymic nurse cell http://purl.obolibrary.org/obo/CL_0002293 epithelial cell of thymus A large epithelial cell found in the thymus. This cell type may internalize thymocytes through extensions of plasma membrane. The cell surface and cytoplasmic vacuoles of a thymic nurse cell express MHC Class I and MHC Class II antigens. The interaction of these antigens with a developing thymocyte determines whether the thymocyte undergoes positive or negative selection. http://purl.obolibrary.org/obo/GO_0002737 negative regulation of plasmacytoid dendritic cell cytokine production http://purl.obolibrary.org/obo/GO_0002736 regulation of plasmacytoid dendritic cell cytokine production Any process that stops, prevents, or reduces the frequency, rate, or extent of plasmacytoid dendritic cell cytokine production. http://purl.obolibrary.org/obo/CL_4030008 pronephric podocyte http://purl.obolibrary.org/obo/CL_0000653 podocyte A specialized epithelial cell that contains "feet" that interdigitate with the "feet" of other glomerular epithelial cells in the pronephros. http://purl.obolibrary.org/obo/GO_0002738 positive regulation of plasmacytoid dendritic cell cytokine production http://purl.obolibrary.org/obo/GO_0002736 regulation of plasmacytoid dendritic cell cytokine production Any process that activates or increases the frequency, rate, or extent of plasmacytoid dendritic cell cytokine production. http://purl.obolibrary.org/obo/CL_0017004 telocyte http://purl.obolibrary.org/obo/CL_0002320 connective tissue cell A supportive cell with a small, oval-shaped body and one to five telopodes. Telopodes are cytoplasmic protrusions from tens to hundreds of micrometers long and mostly below 0.2 microns of caliber. http://purl.obolibrary.org/obo/CL_4030022 renal medullary fibroblast http://purl.obolibrary.org/obo/CL_1000692 kidney interstitial fibroblast A fibroblast that is located in the renal medulla interstitium. http://purl.obolibrary.org/obo/GO_0002759 regulation of antimicrobial humoral response http://purl.obolibrary.org/obo/GO_0031347 regulation of defense response Any process that modulates the frequency, rate, or extent of an antimicrobial humoral response. http://purl.obolibrary.org/obo/CL_4032000 club-like cell of the urethral epithelium http://purl.obolibrary.org/obo/CL_1000296 epithelial cell of urethra An epithelial cell of the urethra that has an expression profile similar to lung club cells. Club-like cells of the urethra epithelium are similar to lung club cells in their expression of SCGB1A1 and in their enrichment of immunomodulatory programs. http://purl.obolibrary.org/obo/GO_0002760 positive regulation of antimicrobial humoral response http://purl.obolibrary.org/obo/GO_0032103 positive regulation of response to external stimulus Any process that activates or increases the frequency, rate, or extent of an antimicrobial humoral response. http://purl.obolibrary.org/obo/CL_0017002 prostate neuroendocrine cell http://purl.obolibrary.org/obo/CL_0000165 neuroendocrine cell A neuroendocrine cell that is part of the prostate epithelium. http://purl.obolibrary.org/obo/GO_0002761 regulation of myeloid leukocyte differentiation http://purl.obolibrary.org/obo/GO_1902105 regulation of leukocyte differentiation Any process that modulates the frequency, rate, or extent of myeloid leukocyte differentiation. http://purl.obolibrary.org/obo/CL_0017003 epithelial cell of prostatic urethra http://purl.obolibrary.org/obo/CL_1000296 epithelial cell of urethra An epithelial cell that is part of the prostatic urethra. http://purl.obolibrary.org/obo/GO_0002762 negative regulation of myeloid leukocyte differentiation http://purl.obolibrary.org/obo/GO_1902106 negative regulation of leukocyte differentiation Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid leukocyte differentiation. http://purl.obolibrary.org/obo/CL_4023158 octopus cell of the mammalian cochlear nucleus http://purl.obolibrary.org/obo/CL_2000029 central nervous system neuron A neuron in the posterior ventral cochlear nucleus that is distinguished by their long, thick and tentacle-shaped dendrites that typically emanate from one side of the cell body. http://purl.obolibrary.org/obo/GO_0002763 positive regulation of myeloid leukocyte differentiation http://purl.obolibrary.org/obo/GO_1902107 positive regulation of leukocyte differentiation Any process that activates or increases the frequency, rate, or extent of myeloid leukocyte differentiation. http://purl.obolibrary.org/obo/CL_4023159 double bouquet cell http://purl.obolibrary.org/obo/CL_0000099 interneuron An interneuron that has double bouquet morphology. http://purl.obolibrary.org/obo/GO_0002775 antimicrobial peptide production http://purl.obolibrary.org/obo/GO_0002440 production of molecular mediator of immune response The synthesis or release of an antimicrobial peptide during an immune response, resulting in an increase in intracellular or extracellular levels. Such peptides may have protective properties against bacteria, fungi, viruses, or protozoa. http://purl.obolibrary.org/obo/CL_4023160 cartwheel cell http://purl.obolibrary.org/obo/CL_0008059 GABA-Gly neuron A neuron of the dorsal cochlear nucleus with spiny dendrites that receive input from the axons of granule cells and with axons that release GABA and glycine onto cartwheel, pyramidal and giant cell targets. http://purl.obolibrary.org/obo/GO_0002776 antimicrobial peptide secretion http://purl.obolibrary.org/obo/GO_0002790 peptide secretion The regulated release of an antimicrobial peptide from a cell or a tissue. Such peptides may have protective properties against bacteria, fungi, viruses, or protozoa. http://purl.obolibrary.org/obo/CL_4023161 unipolar brush cell http://purl.obolibrary.org/obo/CL_0000679 glutamatergic neuron An excitatory glutamatergic interneuron found in the granular layer of the cerebellar cortex and also in the granule cell domain of the cochlear nucleus. Unipolar brush cells have a round or oval cell body with usually a single short dendrite that ends in a brush-like tuft of short dendrites unique to them known as dendrioles. http://purl.obolibrary.org/obo/GO_0002784 regulation of antimicrobial peptide production http://purl.obolibrary.org/obo/GO_0002759 regulation of antimicrobial humoral response Any process that modulates the frequency, rate, or extent of antimicrobial peptide production. http://purl.obolibrary.org/obo/CL_4023162 bushy cell http://purl.obolibrary.org/obo/CL_2000029 central nervous system neuron A neuron found in the anterior part of the ventral cochlear nucleus that has the appearance of bushes, having short dendrites. Bushy cells give outputs to different parts of the superior olivary complex. http://purl.obolibrary.org/obo/GO_0002785 negative regulation of antimicrobial peptide production http://purl.obolibrary.org/obo/GO_0008348 negative regulation of antimicrobial humoral response Any process that stops, prevents, or reduces the frequency, rate, or extent of antimicrobial peptide production. http://purl.obolibrary.org/obo/CL_4023163 spherical bushy cell http://purl.obolibrary.org/obo/CL_4023162 bushy cell A bushy cell that receives only few large excitatory endbulb synapses from auditory nerves. Spherical bush cells give excitatory input to the lateral and medial parts of the superior olive. http://purl.obolibrary.org/obo/GO_0002790 peptide secretion http://purl.obolibrary.org/obo/GO_0046903 secretion The controlled release of a peptide from a cell or a tissue. http://purl.obolibrary.org/obo/CL_4023164 globular bushy cell http://purl.obolibrary.org/obo/CL_4023162 bushy cell A bushy cell that receives a large number of medium-sized synapses, called modified endbulbs. Globular bushy cells extend to the superior olive on both sides of the brainstem where they give input to the bipolar neurons. http://purl.obolibrary.org/obo/GO_0002791 regulation of peptide secretion http://purl.obolibrary.org/obo/GO_0090087 regulation of peptide transport Any process that modulates the frequency, rate, or extent of peptide secretion. http://purl.obolibrary.org/obo/GO_0002792 negative regulation of peptide secretion http://purl.obolibrary.org/obo/GO_0051048 negative regulation of secretion Any process that stops, prevents, or reduces the frequency, rate, or extent of peptide secretion. http://purl.obolibrary.org/obo/GO_0002793 positive regulation of peptide secretion http://purl.obolibrary.org/obo/GO_0051047 positive regulation of secretion Any process that activates or increases the frequency, rate, or extent of peptide secretion. http://purl.obolibrary.org/obo/GO_0002794 regulation of antimicrobial peptide secretion http://purl.obolibrary.org/obo/GO_0002791 regulation of peptide secretion Any process that modulates the frequency, rate, or extent of antimicrobial peptide secretion. http://purl.obolibrary.org/obo/CL_4023170 trigeminal sensory neuron http://purl.obolibrary.org/obo/CL_4023169 trigeminal neuron A trigeminal neuron that is responsible for sensation in the face. http://purl.obolibrary.org/obo/CL_4023171 trigeminal motor neuron http://purl.obolibrary.org/obo/CL_4023169 trigeminal neuron A trigeminal neuron that is responsible for motor functions such as biting and chewing. http://purl.obolibrary.org/obo/CL_4030019 kidney connecting tubule intercalated cell http://purl.obolibrary.org/obo/CL_1000768 kidney connecting tubule epithelial cell A renal intercalated cell that is part of the renal connecting tubule. http://purl.obolibrary.org/obo/CL_4030020 kidney connecting tubule alpha-intercalated cell http://purl.obolibrary.org/obo/CL_0005011 renal alpha-intercalated cell A renal alpha-intercalated cell that is part of the renal connecting tubule. http://purl.obolibrary.org/obo/CL_4030021 kidney connecting tubule beta-intercalated cell http://purl.obolibrary.org/obo/CL_0002201 renal beta-intercalated cell A renal beta-intercalated cell that is part of the renal connecting tubule. http://purl.obolibrary.org/obo/GO_0002795 negative regulation of antimicrobial peptide secretion http://purl.obolibrary.org/obo/GO_0002794 regulation of antimicrobial peptide secretion Any process that stops, prevents, or reduces the frequency, rate, or extent of antimicrobial peptide secretion. http://purl.obolibrary.org/obo/CL_4030023 respiratory tract hillock cell http://purl.obolibrary.org/obo/CL_0002368 respiratory tract epithelial cell A hillock cell that is located in respiratory epithelium. In some mammalian species, this cell type has been noted to express KRT13 and KRT4 and is postulated to play a role in squamous barrier function and immunomodulation. http://purl.obolibrary.org/obo/GO_0002796 positive regulation of antimicrobial peptide secretion http://purl.obolibrary.org/obo/GO_0002794 regulation of antimicrobial peptide secretion Any process that activates or increases the frequency, rate, or extent of antimicrobial peptide secretion. http://purl.obolibrary.org/obo/CL_4030024 hillock cell http://purl.obolibrary.org/obo/CL_0000066 epithelial cell An epithelial, transitional cell type between basal and secretory; located in stratified, non-ciliated structures (called hillocks) with high cell turnover in epithelium. In some mammalian species, this cell type has been noted to express KRT13 and is postulated to play a role in squamous barrier function and immunomodulation. http://purl.obolibrary.org/obo/GO_0002819 regulation of adaptive immune response http://purl.obolibrary.org/obo/GO_0050776 regulation of immune response Any process that modulates the frequency, rate, or extent of an adaptive immune response. http://purl.obolibrary.org/obo/CL_4030025 renal cortical fibroblast http://purl.obolibrary.org/obo/CL_1000692 kidney interstitial fibroblast A fibroblast that is located in the renal cortical interstitium. http://purl.obolibrary.org/obo/GO_0002820 negative regulation of adaptive immune response http://purl.obolibrary.org/obo/GO_0050777 negative regulation of immune response Any process that stops, prevents, or reduces the frequency, rate, or extent of an adaptive immune response. http://purl.obolibrary.org/obo/CL_0004236 AB broad diffuse-2 amacrine cell http://purl.obolibrary.org/obo/CL_0004252 medium field retinal amacrine cell An amacrine cell with a medium dendritic field and post-synaptic terminals in S2, S3, and S4. This cell type releases the neurotransmitter gamma-aminobutyric acid (GABA). http://purl.obolibrary.org/obo/CL_4023033 OFF retinal ganglion cell http://purl.obolibrary.org/obo/CL_0000740 retinal ganglion cell A retinal ganglion cell that is depolarized by decreased illumination of their receptive field center. http://purl.obolibrary.org/obo/GO_0002821 positive regulation of adaptive immune response http://purl.obolibrary.org/obo/GO_0050778 positive regulation of immune response Any process that activates or increases the frequency, rate, or extent of an adaptive immune response. http://purl.obolibrary.org/obo/CL_4030031 interstitial cell http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell Any cell that is located within the interstitium between the cells most prominent in defining a given tissue. "Interstitial cell" is a morphological term and refers to a variety of cells with differing origins and phenotypes. http://purl.obolibrary.org/obo/GO_0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains http://purl.obolibrary.org/obo/GO_0002819 regulation of adaptive immune response Any process that modulates the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata. http://purl.obolibrary.org/obo/CL_4030032 valve interstitial cell http://purl.obolibrary.org/obo/CL_1000147 cardiac valve cell An interstitial cell that is part of a cardiac valve leaflet. Along with valve endothelial cells, a valve interstitial cell maintains tissue homeostasis for the function of cardiac valves through secreting biochemical signals, matrix proteins and matrix remodeling enzymes. http://purl.obolibrary.org/obo/GO_0002823 negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains http://purl.obolibrary.org/obo/GO_0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains Any process that stops, prevents, or reduces the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata. http://purl.obolibrary.org/obo/CL_4030033 valve endothelial cell http://purl.obolibrary.org/obo/CL_1000147 cardiac valve cell An endothelial cell that lines a surface of a cardiac valve leaflet. Along with valve interstitial cells, a valve endothelial cell maintains tissue homeostasis for the function of cardiac valves through secreting biochemical signals, matrix proteins and matrix remodeling enzymes. http://purl.obolibrary.org/obo/GO_0002824 positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains http://purl.obolibrary.org/obo/GO_0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains Any process that activates or increases the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata. http://purl.obolibrary.org/obo/UBERON_8600000 lobular bronchiole http://purl.obolibrary.org/obo/UBERON_0002186 bronchiole A conductive airway that branches into terminal bronchioles. http://purl.obolibrary.org/obo/UBERON_8600001 epithelium of lobular bronchiole http://purl.obolibrary.org/obo/UBERON_0002051 epithelium of bronchiole An epithelium of the lobular bronchiole. http://purl.obolibrary.org/obo/GO_0002825 regulation of T-helper 1 type immune response http://purl.obolibrary.org/obo/GO_0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains Any process that modulates the frequency, rate, or extent of a T-helper 1 type immune response. http://purl.obolibrary.org/obo/UBERON_8600002 mucosa of lobular bronchiole http://purl.obolibrary.org/obo/UBERON_0005039 mucosa of bronchiole A mucosa that is part of a lobular bronchiole. http://purl.obolibrary.org/obo/GO_0002826 negative regulation of T-helper 1 type immune response http://purl.obolibrary.org/obo/GO_0002825 regulation of T-helper 1 type immune response Any process that stops, prevents, or reduces the frequency, rate, or extent of a T-helper 1 type immune response. http://purl.obolibrary.org/obo/UBERON_8600003 smooth muscle tissue of lobular bronchiole http://purl.obolibrary.org/obo/UBERON_0004515 smooth muscle tissue of bronchiole A smooth muscle tissue that is part of a lobular bronchiole. http://purl.obolibrary.org/obo/GO_0002827 positive regulation of T-helper 1 type immune response http://purl.obolibrary.org/obo/GO_0002825 regulation of T-helper 1 type immune response Any process that activates or increases the frequency, rate, or extent of a T-helper 1 type immune response. http://purl.obolibrary.org/obo/CL_4033021 myoepithelial cell of trachea gland http://purl.obolibrary.org/obo/CL_0000307 tracheal epithelial cell A myoepithelial cell that is part of a submucosal gland of the trachea. http://purl.obolibrary.org/obo/GO_0002828 regulation of type 2 immune response http://purl.obolibrary.org/obo/GO_0050776 regulation of immune response Any process that modulates the frequency, rate, or extent of a type 2 immune response. http://purl.obolibrary.org/obo/CL_4033024 airway submucosal gland duct basal cell http://purl.obolibrary.org/obo/CL_0000646 basal cell A basal cell that is part of a duct of an airway submucosal gland. http://purl.obolibrary.org/obo/GO_0002829 negative regulation of type 2 immune response http://purl.obolibrary.org/obo/GO_0050777 negative regulation of immune response Any process that stops, prevents, or reduces the frequency, rate, or extent of a type 2 immune response. http://purl.obolibrary.org/obo/CL_4033020 mucus secreting cell of trachea gland http://purl.obolibrary.org/obo/CL_4033037 mucus secreting cell of tracheobronchial tree submucosal gland A mucus secreting cell that is part of a submucosal gland of the trachea. http://purl.obolibrary.org/obo/GO_0002830 positive regulation of type 2 immune response http://purl.obolibrary.org/obo/GO_0050778 positive regulation of immune response Any process that activates or increases the frequency, rate, or extent of a type 2 immune response. http://purl.obolibrary.org/obo/CL_4033022 mucus secreting cell of bronchus submucosal gland http://purl.obolibrary.org/obo/CL_4033037 mucus secreting cell of tracheobronchial tree submucosal gland A mucus secreting cell of a submucosal gland of the bronchus. http://purl.obolibrary.org/obo/GO_0002831 regulation of response to biotic stimulus http://purl.obolibrary.org/obo/GO_0048583 regulation of response to stimulus Any process that modulates the frequency, rate, or extent of a response to biotic stimulus. http://purl.obolibrary.org/obo/UBERON_8480069 temporofacial region http://purl.obolibrary.org/obo/UBERON_0001444 subdivision of head The region at each side of the face comprising the temple and the cheek. http://purl.obolibrary.org/obo/GO_0002832 negative regulation of response to biotic stimulus http://purl.obolibrary.org/obo/GO_0048585 negative regulation of response to stimulus Any process that stops, prevents, or reduces the frequency, rate, or extent of a response to biotic stimulus. http://purl.obolibrary.org/obo/GO_0002833 positive regulation of response to biotic stimulus http://purl.obolibrary.org/obo/GO_0048584 positive regulation of response to stimulus Any process that activates or increases the frequency, rate, or extent of a response to biotic stimulus. http://purl.obolibrary.org/obo/GO_0014000 morula development http://purl.obolibrary.org/obo/GO_0009790 embryo development The process whose specific outcome is the progression of the morula over time. The morula is a spherical embryonic mass of blastomeres formed before the blastula and resulting from cleavage of the fertilized ovum. http://purl.obolibrary.org/obo/GO_0002849 regulation of peripheral T cell tolerance induction http://purl.obolibrary.org/obo/GO_0002709 regulation of T cell mediated immunity Any process that modulates the frequency, rate, or extent of peripheral T cell tolerance induction. http://purl.obolibrary.org/obo/CL_4301582 CBX Purkinje Gaba_1 Purkinje cell (Mmus) http://purl.obolibrary.org/obo/CL_4300353 Purkinje cell (Mmus) A Purkinje cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Pcp2 (Mmus), Stk17b (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1152 CBX Purkinje Gaba_1. http://purl.obolibrary.org/obo/GO_0002850 negative regulation of peripheral T cell tolerance induction http://purl.obolibrary.org/obo/GO_0002849 regulation of peripheral T cell tolerance induction Any process that stops, prevents, or reduces the frequency, rate, or extent of peripheral T cell tolerance induction. http://purl.obolibrary.org/obo/CL_4307043 Astro-TE NN_2 Mcm6 astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301592 Astro-TE NN_2 astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Mcm6 (Mmus), Egfr (Mmus), Pcsk6 (Mmus). It is distinguished from other Astro-TE NN_2 cells by expression of Mcm6. These cells are located in the Hippocampal region , in or close to the regions: Dentate gyrus, molecular layer, Dentate gyrus, polymorph layer, Dentate gyrus, granule cell layer . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5223 Astro-TE NN_2. http://purl.obolibrary.org/obo/GO_0002851 positive regulation of peripheral T cell tolerance induction http://purl.obolibrary.org/obo/GO_0002849 regulation of peripheral T cell tolerance induction Any process that activates or increases the frequency, rate, or extent of peripheral T cell tolerance induction. http://purl.obolibrary.org/obo/CL_4033150 nodose ganglion TRPV2 neuron http://purl.obolibrary.org/obo/CL_0000101 sensory neuron A sensory neuron that has the soma located in the nodose ganglion and expresses the marker transient receptor potential vanilloid 2 (TRPV2). http://purl.obolibrary.org/obo/GO_0002867 regulation of B cell deletion http://purl.obolibrary.org/obo/GO_1904748 regulation of apoptotic process involved in development Any process that modulates the frequency, rate, or extent of B cell deletion. http://purl.obolibrary.org/obo/CL_0000000 cell http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure A material entity of anatomical origin (part of or deriving from an organism) that has as its parts a maximally connected cell compartment surrounded by a plasma membrane. http://purl.obolibrary.org/obo/CL_0000001 primary cultured cell http://purl.obolibrary.org/obo/CL_0000010 cultured cell A cultured cell that is freshly isolated from a organismal source, or derives in culture from such a cell prior to the culture being passaged. http://purl.obolibrary.org/obo/GO_0002868 negative regulation of B cell deletion http://purl.obolibrary.org/obo/GO_1904746 negative regulation of apoptotic process involved in development Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell deletion. http://purl.obolibrary.org/obo/CL_0000005 neural crest derived fibroblast http://purl.obolibrary.org/obo/CL_0000057 fibroblast Any fibroblast that is derived from the neural crest. http://purl.obolibrary.org/obo/CL_0000006 neuronal receptor cell http://purl.obolibrary.org/obo/CL_0000197 sensory receptor cell Any sensory receptor cell that is a(n) neuron and is capable of some detection of stimulus involved in sensory perception. http://purl.obolibrary.org/obo/GO_0002869 positive regulation of B cell deletion http://purl.obolibrary.org/obo/GO_1904747 positive regulation of apoptotic process involved in development Any process that activates or increases the frequency, rate, or extent of B cell deletion. http://purl.obolibrary.org/obo/CL_0000007 early embryonic cell (metazoa) http://purl.obolibrary.org/obo/CL_0002321 embryonic cell (metazoa) A cell found in the embryo before the formation of all the gem layers is complete. http://purl.obolibrary.org/obo/GO_0002870 T cell anergy http://purl.obolibrary.org/obo/GO_0002517 T cell tolerance induction Any process contributing to anergy in T cells, a state of functional inactivation which is part of T cell tolerance induction. http://purl.obolibrary.org/obo/CL_0000008 migratory cranial neural crest cell http://purl.obolibrary.org/obo/CL_0000333 migratory neural crest cell Cell that is part of the migratory cranial neural crest population. Migratory cranial neural crest cells develop from premigratory cranial neural crest cells and have undergone epithelial to mesenchymal transition and delamination. http://purl.obolibrary.org/obo/GO_0002871 regulation of natural killer cell tolerance induction http://purl.obolibrary.org/obo/GO_0002643 regulation of tolerance induction Any process that modulates the frequency, rate, or extent of natural killer cell tolerance induction. http://purl.obolibrary.org/obo/CL_0000010 cultured cell http://purl.obolibrary.org/obo/CL_0000578 experimentally modified cell in vitro A cell in vitro that is or has been maintained or propagated as part of a cell culture. http://purl.obolibrary.org/obo/GO_0002872 negative regulation of natural killer cell tolerance induction http://purl.obolibrary.org/obo/GO_0002871 regulation of natural killer cell tolerance induction Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell tolerance induction. http://purl.obolibrary.org/obo/CL_0000011 migratory trunk neural crest cell http://purl.obolibrary.org/obo/CL_0000333 migratory neural crest cell Cell that is part of the migratory trunk neural crest population. Migratory trunk neural crest cells develop from premigratory trunk neural crest cells and have undergone epithelial to mesenchymal transition and delamination. http://purl.obolibrary.org/obo/GO_0002873 positive regulation of natural killer cell tolerance induction http://purl.obolibrary.org/obo/GO_0002871 regulation of natural killer cell tolerance induction Any process that activates or increases the frequency, rate, or extent of natural killer cell tolerance induction. http://purl.obolibrary.org/obo/CL_0000014 germ line stem cell http://purl.obolibrary.org/obo/CL_0000039 germ line cell A stem cell that is the precursor of gametes. http://purl.obolibrary.org/obo/GO_0002886 regulation of myeloid leukocyte mediated immunity http://purl.obolibrary.org/obo/GO_0002703 regulation of leukocyte mediated immunity Any process that modulates the frequency, rate, or extent of myeloid leukocyte mediated immunity. http://purl.obolibrary.org/obo/CL_0000015 male germ cell http://purl.obolibrary.org/obo/CL_0000586 germ cell A germ cell that supports male gamete production. In some species, non-germ cells known as Sertoli cells also play a role in spermatogenesis. http://purl.obolibrary.org/obo/GO_0002887 negative regulation of myeloid leukocyte mediated immunity http://purl.obolibrary.org/obo/GO_0002886 regulation of myeloid leukocyte mediated immunity Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid leukocyte mediated immunity. http://purl.obolibrary.org/obo/CL_0000016 male germ line stem cell http://purl.obolibrary.org/obo/CL_0000015 male germ cell A stem cell that is the precursor of male gametes. http://purl.obolibrary.org/obo/GO_0002888 positive regulation of myeloid leukocyte mediated immunity http://purl.obolibrary.org/obo/GO_0002886 regulation of myeloid leukocyte mediated immunity Any process that activates or increases the frequency, rate, or extent of myeloid leukocyte mediated immunity. http://purl.obolibrary.org/obo/CL_0000017 spermatocyte http://purl.obolibrary.org/obo/CL_0000015 male germ cell A male germ cell that develops from spermatogonia. The euploid primary spermatocytes undergo meiosis and give rise to the haploid secondary spermatocytes which in turn give rise to spermatids. http://purl.obolibrary.org/obo/GO_0002889 regulation of immunoglobulin mediated immune response http://purl.obolibrary.org/obo/GO_0002712 regulation of B cell mediated immunity Any process that modulates the frequency, rate, or extent of an immunoglobulin mediated immune response. http://purl.obolibrary.org/obo/CL_0000018 spermatid http://purl.obolibrary.org/obo/CL_0000413 haploid cell A male germ cell that develops from the haploid secondary spermatocytes. Without further division, spermatids undergo structural changes and give rise to spermatozoa. http://purl.obolibrary.org/obo/GO_0002890 negative regulation of immunoglobulin mediated immune response http://purl.obolibrary.org/obo/GO_0002889 regulation of immunoglobulin mediated immune response Any process that stops, prevents, or reduces the frequency, rate, or extent of an immunoglobulin mediated immune response. http://purl.obolibrary.org/obo/CL_0000019 sperm http://purl.obolibrary.org/obo/CL_0000408 male gamete A mature male germ cell that develops from a spermatid. http://purl.obolibrary.org/obo/GO_0002891 positive regulation of immunoglobulin mediated immune response http://purl.obolibrary.org/obo/GO_0002889 regulation of immunoglobulin mediated immune response Any process that activates or increases the frequency, rate, or extent of an immunoglobulin mediated immune response. http://purl.obolibrary.org/obo/CL_0000020 spermatogonium http://purl.obolibrary.org/obo/CL_0000015 male germ cell An euploid male germ cell of an early stage of spermatogenesis. http://purl.obolibrary.org/obo/GO_0002901 mature B cell apoptotic process http://purl.obolibrary.org/obo/GO_0001783 B cell apoptotic process Any apoptotic process in a B cell that is mature, having left the bone marrow. http://purl.obolibrary.org/obo/CL_0000021 female germ cell http://purl.obolibrary.org/obo/CL_0000586 germ cell Female germ cell is a germ cell that supports female gamete production. http://purl.obolibrary.org/obo/GO_0002902 regulation of B cell apoptotic process http://purl.obolibrary.org/obo/GO_0070228 regulation of lymphocyte apoptotic process Any process that modulates the frequency, rate, or extent of B cell apoptotic process. http://purl.obolibrary.org/obo/CL_0000022 female germ line stem cell http://purl.obolibrary.org/obo/CL_0000021 female germ cell A stem cell that is the precursor of female gametes. http://purl.obolibrary.org/obo/GO_0002903 negative regulation of B cell apoptotic process http://purl.obolibrary.org/obo/GO_0070229 negative regulation of lymphocyte apoptotic process Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell apoptotic process. http://purl.obolibrary.org/obo/CL_0000023 oocyte http://purl.obolibrary.org/obo/CL_0000021 female germ cell A female germ cell that has entered meiosis. http://purl.obolibrary.org/obo/GO_0002904 positive regulation of B cell apoptotic process http://purl.obolibrary.org/obo/GO_0070230 positive regulation of lymphocyte apoptotic process Any process that activates or increases the frequency, rate, or extent of B cell apoptotic process. http://purl.obolibrary.org/obo/CL_0000024 oogonial cell http://purl.obolibrary.org/obo/CL_0000021 female germ cell An undifferentiated germ cell that proliferates rapidly and gives rise to oocytes. http://purl.obolibrary.org/obo/GO_0002905 regulation of mature B cell apoptotic process http://purl.obolibrary.org/obo/GO_0002902 regulation of B cell apoptotic process Any process that modulates the frequency, rate, or extent of mature B cell apoptotic process. http://purl.obolibrary.org/obo/CL_0000025 egg cell http://purl.obolibrary.org/obo/CL_0000675 female gamete A female gamete where meiosis has progressed to metaphase II and is able to participate in fertilization. http://purl.obolibrary.org/obo/GO_0002906 negative regulation of mature B cell apoptotic process http://purl.obolibrary.org/obo/GO_0002905 regulation of mature B cell apoptotic process Any process that stops, prevents, or reduces the frequency, rate, or extent of mature B cell apoptotic process. http://purl.obolibrary.org/obo/CL_0000026 invertebrate nurse cell http://purl.obolibrary.org/obo/CL_4029002 germline-derived nurse cell A germline cell that contributes to the development of the oocyte by transferring cytoplasm directly to oocyte. http://purl.obolibrary.org/obo/GO_0002907 positive regulation of mature B cell apoptotic process http://purl.obolibrary.org/obo/GO_0002905 regulation of mature B cell apoptotic process Any process that activates or increases the frequency, rate, or extent of mature B cell apoptotic process. http://purl.obolibrary.org/obo/CL_0000027 smooth muscle cell neural crest derived http://purl.obolibrary.org/obo/CL_0000192 smooth muscle cell A smooth muscle cell derived from the neural crest. http://purl.obolibrary.org/obo/GO_0002911 regulation of lymphocyte anergy http://purl.obolibrary.org/obo/GO_0002643 regulation of tolerance induction Any process that modulates the frequency, rate, or extent of lymphocyte anergy. http://purl.obolibrary.org/obo/CL_0000029 neural crest derived neuron http://purl.obolibrary.org/obo/CL_0000540 neuron Any neuron that develops from some migratory neural crest cell. http://purl.obolibrary.org/obo/GO_0002912 negative regulation of lymphocyte anergy http://purl.obolibrary.org/obo/GO_0002911 regulation of lymphocyte anergy Any process that stops, prevents, or reduces the frequency, rate, or extent of lymphocyte anergy. http://purl.obolibrary.org/obo/CL_0000030 glioblast http://purl.obolibrary.org/obo/CL_0011026 progenitor cell A non-terminally differentiated cell that develops form the neuroectoderm. Glioblast has the potential to differentiate into various types of glial cells, including astrocytes and oligodendrocytes. http://purl.obolibrary.org/obo/GO_0002913 positive regulation of lymphocyte anergy http://purl.obolibrary.org/obo/GO_0002911 regulation of lymphocyte anergy Any process that activates or increases the frequency, rate, or extent of lymphocyte anergy. http://purl.obolibrary.org/obo/CL_0000031 neuroblast (sensu Vertebrata) http://purl.obolibrary.org/obo/CL_0011026 progenitor cell A cell that will develop into a neuron often after a migration phase. http://purl.obolibrary.org/obo/GO_0002920 regulation of humoral immune response http://purl.obolibrary.org/obo/GO_0050776 regulation of immune response Any process that modulates the frequency, rate, or extent of a humoral immune response. http://purl.obolibrary.org/obo/CL_0000032 neuroplacodal cell http://purl.obolibrary.org/obo/CL_0002321 embryonic cell (metazoa) A cell of a platelike structure, especially a thickened plate of ectoderm in the early embryo, from which a sense organ develops. http://purl.obolibrary.org/obo/GO_0002921 negative regulation of humoral immune response http://purl.obolibrary.org/obo/GO_0050777 negative regulation of immune response Any process that stops, prevents, or reduces the frequency, rate, or extent of a humoral immune response. http://purl.obolibrary.org/obo/CL_0000033 apocrine cell http://purl.obolibrary.org/obo/CL_0000152 exocrine cell An exocrine cell characterized by loss of part of the cytoplasm during the process of secretion. The secreted substance is accumulated at the apical end and is either budded off through the plasma membrane producing secreted vesicles or dissolved in the cytoplasm that is lost during secretion. http://purl.obolibrary.org/obo/GO_0002922 positive regulation of humoral immune response http://purl.obolibrary.org/obo/GO_0050778 positive regulation of immune response Any process that activates or increases the frequency, rate, or extent of a humoral immune response. http://purl.obolibrary.org/obo/CL_0000034 stem cell http://purl.obolibrary.org/obo/CL_0011115 precursor cell A relatively undifferentiated cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells. http://purl.obolibrary.org/obo/GO_0002930 trabecular meshwork development http://purl.obolibrary.org/obo/GO_0009888 tissue development The progression of the trabecular meshwork over time, from its formation to the mature structure. The trabecular meshwork is a fenestrated endothelial-like tissue situated at the intersection of the cornea and the iris. The trabecular meshwork provides drainage for the aqueous humor. http://purl.obolibrary.org/obo/CL_0000035 single fate stem cell http://purl.obolibrary.org/obo/CL_0000723 somatic stem cell A stem cell that self-renews as well as give rise to a single mature cell type. http://purl.obolibrary.org/obo/GO_0002932 tendon sheath development http://purl.obolibrary.org/obo/GO_0061448 connective tissue development The process whose specific outcome is the progression of a tendon sheath over time, from its formation to the mature structure. A tendon sheath is a layer of membrane around a tendon. It permits the tendon to move. http://purl.obolibrary.org/obo/CL_0000036 epithelial fate stem cell http://purl.obolibrary.org/obo/CL_0000723 somatic stem cell A somatic stem cell that is committed to an epithelial fate, possessing the capacity for self-renewal and the ability to differentiate into one or more distinct mature cell types of the epithelial lineage. This cell is crucial for the development, homeostasis, repair, and regeneration of epithelial tissues. http://purl.obolibrary.org/obo/GO_0002934 desmosome organization http://purl.obolibrary.org/obo/GO_0045216 cell-cell junction organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a desmosome. A desmosome is a patch-like intercellular junction found in vertebrate tissues, consisting of parallel zones of two cell membranes, separated by an space of 25-35 nm, and having dense fibrillar plaques in the subjacent cytoplasm. http://purl.obolibrary.org/obo/CL_0000037 hematopoietic stem cell http://purl.obolibrary.org/obo/CL_0011026 progenitor cell A stem cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system. Hematopoietic stem cells lack cell markers of effector cells (lin-negative). Lin-negative is defined by lacking one or more of the following cell surface markers: CD2, CD3 epsilon, CD4, CD5 ,CD8 alpha chain, CD11b, CD14, CD19, CD20, CD56, ly6G, ter119. http://purl.obolibrary.org/obo/GO_0002941 synoviocyte proliferation http://purl.obolibrary.org/obo/GO_0050673 epithelial cell proliferation The multiplication or reproduction of type B synoviocytes by cell division, resulting in the expansion of their population. A type B synoviocyte is a fibroblast-like cell found in synovial tissues. http://purl.obolibrary.org/obo/CL_0000038 erythroid progenitor cell http://purl.obolibrary.org/obo/CL_0000839 myeloid lineage restricted progenitor cell A progenitor cell committed to the erythroid lineage. http://purl.obolibrary.org/obo/CL_0000039 germ line cell http://purl.obolibrary.org/obo/CL_0000000 cell A cell that is within the developmental lineage of gametes and is able to pass along its genetic material to offspring. http://purl.obolibrary.org/obo/GO_0003002 regionalization http://purl.obolibrary.org/obo/GO_0007389 pattern specification process The pattern specification process that results in the subdivision of an axis or axes in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment. http://purl.obolibrary.org/obo/CL_0000040 monoblast http://purl.obolibrary.org/obo/CL_0002194 monopoietic cell A myeloid progenitor cell committed to the monocyte lineage. This cell is CD11b-positive, has basophilic cytoplasm, euchromatin, and the presence of a nucleolus. http://purl.obolibrary.org/obo/GO_0003006 developmental process involved in reproduction http://purl.obolibrary.org/obo/GO_0032502 developmental process A developmental process in which a progressive change in the state of some part of an organism, germline or somatic, specifically contributes to its ability to form offspring. http://purl.obolibrary.org/obo/CL_0000041 mature eosinophil http://purl.obolibrary.org/obo/CL_0000771 eosinophil A fully differentiated eosinophil, a granular leukocyte with a nucleus that usually has two lobes connected by one or more slender threads, and cytoplasm containing coarse, round granules that are uniform in size and which can be stained by the dye eosin. Cells are also differentiated from other granulocytes by a small nuclear-to-cytoplasm ratio (1:3). This cell type is CD49d-positive. http://purl.obolibrary.org/obo/GO_0003007 heart morphogenesis http://purl.obolibrary.org/obo/GO_0009887 animal organ morphogenesis The developmental process in which the heart is generated and organized. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. http://purl.obolibrary.org/obo/CL_0000042 neutrophilic myeloblast http://purl.obolibrary.org/obo/CL_0000835 myeloblast A myeloblast committed to the neutrophil lineage. This cell type is GATA-1 positive, C/EBPa-positive, AML-1-positive, c-myb-positive and has low expression of PU.1 transcription factor. http://purl.obolibrary.org/obo/GO_0003008 system process http://purl.obolibrary.org/obo/GO_0032501 multicellular organismal process A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective. http://purl.obolibrary.org/obo/CL_0000043 mature basophil http://purl.obolibrary.org/obo/CL_0002274 histamine secreting cell A fully differentiated basophil, a granular leukocyte with an irregularly shaped, pale-staining nucleus that is partially constricted into two lobes, and with cytoplasm that contains coarse granules of variable size. Basophils contain vasoactive amines such as histamine and serotonin, which are released on appropriate stimulation. http://purl.obolibrary.org/obo/GO_0003009 skeletal muscle contraction http://purl.obolibrary.org/obo/GO_0006941 striated muscle contraction A process in which force is generated within skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the skeletal muscle, the muscle contraction takes advantage of an ordered sarcomeric structure and in most cases it is under voluntary control. http://purl.obolibrary.org/obo/CL_0000047 neural stem cell http://purl.obolibrary.org/obo/CL_0002319 neural cell An undifferentiated neural cell that originates from the neuroectoderm and has the capacity both to perpetually self-renew without differentiating and to generate multiple central nervous system neuronal and glial cell types. http://purl.obolibrary.org/obo/GO_0003012 muscle system process http://purl.obolibrary.org/obo/GO_0003008 system process An organ system process carried out at the level of a muscle. Muscle tissue is composed of contractile cells or fibers. http://purl.obolibrary.org/obo/CL_0000048 multi fate stem cell http://purl.obolibrary.org/obo/CL_0000034 stem cell A stem cell that can give rise to multiple lineages of cells. http://purl.obolibrary.org/obo/CL_0000049 common myeloid progenitor http://purl.obolibrary.org/obo/CL_0002032 hematopoietic oligopotent progenitor cell A progenitor cell committed to myeloid lineage, including the megakaryocyte and erythroid lineages. http://purl.obolibrary.org/obo/GO_0003013 circulatory system process http://purl.obolibrary.org/obo/GO_0003008 system process An organ system process carried out by any of the organs or tissues of the circulatory system. The circulatory system is an organ system that moves extracellular fluids to and from tissue within a multicellular organism. http://purl.obolibrary.org/obo/CL_0000050 megakaryocyte-erythroid progenitor cell http://purl.obolibrary.org/obo/CL_0011026 progenitor cell A progenitor cell committed to the megakaryocyte and erythroid lineages. http://purl.obolibrary.org/obo/GO_0003014 renal system process http://purl.obolibrary.org/obo/GO_0003008 system process An organ system process carried out by any of the organs or tissues of the renal system. The renal system maintains fluid balance, and contributes to electrolyte balance, acid/base balance, and disposal of nitrogenous waste products. In humans, the renal system comprises a pair of kidneys, a pair of ureters, urinary bladder, urethra, sphincter muscle and associated blood vessels; in other species, the renal system may comprise related structures (e.g., nephrocytes and malpighian tubules in Drosophila). http://purl.obolibrary.org/obo/CL_0000051 common lymphoid progenitor http://purl.obolibrary.org/obo/CL_0011026 progenitor cell A oligopotent progenitor cell committed to the lymphoid lineage. http://purl.obolibrary.org/obo/GO_0003015 heart process http://purl.obolibrary.org/obo/GO_0003013 circulatory system process A circulatory system process carried out by the heart. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. http://purl.obolibrary.org/obo/CL_0000052 totipotent stem cell http://purl.obolibrary.org/obo/CL_0000723 somatic stem cell A stem cell from which all cells of the body can form. http://purl.obolibrary.org/obo/GO_0003016 respiratory system process http://purl.obolibrary.org/obo/GO_0003008 system process A process carried out by the organs or tissues of the respiratory system. The respiratory system is an organ system responsible for respiratory gaseous exchange. http://purl.obolibrary.org/obo/CL_0000056 myoblast http://purl.obolibrary.org/obo/CL_0000680 muscle precursor cell A cell that is commited to differentiating into a muscle cell. Embryonic myoblasts develop from the mesoderm. They undergo proliferation, migrate to their various sites, and then differentiate into the appropriate form of myocytes. Myoblasts also occur as transient populations of cells in muscles undergoing repair. http://purl.obolibrary.org/obo/GO_0003018 vascular process in circulatory system http://purl.obolibrary.org/obo/GO_0003013 circulatory system process A circulatory process that occurs at the level of the vasculature. http://purl.obolibrary.org/obo/CL_0000057 fibroblast http://purl.obolibrary.org/obo/CL_0000499 stromal cell A connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. Flattened and irregular in outline with branching processes; appear fusiform or spindle-shaped. http://purl.obolibrary.org/obo/GO_0003032 detection of oxygen http://purl.obolibrary.org/obo/GO_0070482 response to oxygen levels The series of events in which an oxygen stimulus is received by a cell and converted into a molecular signal. http://purl.obolibrary.org/obo/CL_0000058 chondroblast http://purl.obolibrary.org/obo/CL_0011026 progenitor cell Skeletogenic cell that is typically non-terminally differentiated, secretes an avascular, GAG rich matrix; is not buried in cartilage tissue matrix, retains the ability to divide, located adjacent to cartilage tissue (including within the perichondrium), and develops from prechondroblast (and thus prechondrogenic) cell. http://purl.obolibrary.org/obo/GO_0003044 regulation of systemic arterial blood pressure mediated by a chemical signal http://purl.obolibrary.org/obo/GO_0003073 regulation of systemic arterial blood pressure The regulation of blood pressure mediated by biochemical signaling: hormonal, autocrine or paracrine. http://purl.obolibrary.org/obo/CL_0000059 ameloblast http://purl.obolibrary.org/obo/CL_0002077 ecto-epithelial cell Skeletogenic cell that produces enamel, overlies the odontogenic papilla, and arises from the differentiation of a preameloblast cell. http://purl.obolibrary.org/obo/GO_0003071 renal system process involved in regulation of systemic arterial blood pressure http://purl.obolibrary.org/obo/GO_0003014 renal system process Renal process that modulates the force with which blood travels through the circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure. http://purl.obolibrary.org/obo/CL_0000060 odontoblast http://purl.obolibrary.org/obo/CL_0002148 dental pulp cell Skeletogenic cell that secretes dentine matrix, is derived from the odontogenic papilla, and develops from a preodontoblast cell. http://purl.obolibrary.org/obo/CL_0000061 cementoblast http://purl.obolibrary.org/obo/CL_0000151 secretory cell Skeletogenic cell that produces cementum (a bony substance that covers the root of a tooth), is part of the odontogenic papilla, and develops from a precementoblast cell. http://purl.obolibrary.org/obo/GO_0003073 regulation of systemic arterial blood pressure http://purl.obolibrary.org/obo/GO_0008217 regulation of blood pressure The process that modulates the force with which blood travels through the systemic arterial circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure. http://purl.obolibrary.org/obo/CL_0000062 osteoblast http://purl.obolibrary.org/obo/CL_0002320 connective tissue cell Skeletogenic cell that secretes osteoid, is capable of producing mineralized (hydroxyapatite) matrix, is located adjacent to or within osteoid tissue, and arises from the transformation of a preosteoblast cell. http://purl.obolibrary.org/obo/GO_0003081 regulation of systemic arterial blood pressure by renin-angiotensin http://purl.obolibrary.org/obo/GO_0001990 regulation of systemic arterial blood pressure by hormone The process in which renin-angiotensin modulates the force with which blood passes through the circulatory system. http://purl.obolibrary.org/obo/CL_0000064 ciliated cell http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell A cell that has a filiform extrusion of the cell surface. http://purl.obolibrary.org/obo/GO_0003091 renal water homeostasis http://purl.obolibrary.org/obo/GO_0050891 multicellular organismal-level water homeostasis Renal process involved in the maintenance of an internal steady state of water in the body. http://purl.obolibrary.org/obo/CL_0000065 ependymal cell http://purl.obolibrary.org/obo/CL_0000710 neurecto-epithelial cell A neuroepithelial glial cell, derived from a radial glial cell originating from the neuroectoderm, lines the ventricles of the brain and the central canal of the spinal cord. This cell is characterized by the presence of cilia on its apical surface, which can be motile or non-motile. http://purl.obolibrary.org/obo/GO_0003093 regulation of glomerular filtration http://purl.obolibrary.org/obo/GO_0098801 regulation of renal system process Any process that modulates the frequency, rate or extent of glomerular filtration. Glomerular filtration is the process in which blood is filtered by the glomerulus into the renal tubule. http://purl.obolibrary.org/obo/CL_0000066 epithelial cell http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell A cell that is usually found in a two-dimensional sheet with a free surface. The cell has a cytoskeleton that allows for tight cell to cell contact and for cell polarity where apical part is directed towards the lumen and the basal part to the basal lamina. http://purl.obolibrary.org/obo/GO_0003094 glomerular filtration http://purl.obolibrary.org/obo/GO_0097205 renal filtration The process in which plasma is filtered through the glomerular membrane which consists of capillary endothelial cells, the basement membrane, and epithelial cells. The glomerular filtrate is the same as plasma except it has no significant amount of protein. http://purl.obolibrary.org/obo/CL_0000067 ciliated epithelial cell http://purl.obolibrary.org/obo/CL_0000066 epithelial cell An epithelial cell that has a cilia. http://purl.obolibrary.org/obo/CL_0000068 duct epithelial cell http://purl.obolibrary.org/obo/CL_0000066 epithelial cell An epithelial cell that is part of a duct. http://purl.obolibrary.org/obo/GO_0003096 renal sodium ion transport http://purl.obolibrary.org/obo/GO_0006814 sodium ion transport The directed movement of sodium ions (Na+) by the renal system. http://purl.obolibrary.org/obo/CL_0000071 blood vessel endothelial cell http://purl.obolibrary.org/obo/CL_0002139 endothelial cell of vascular tree An endothelial cell that lines the vasculature. http://purl.obolibrary.org/obo/GO_0003097 renal water transport http://purl.obolibrary.org/obo/GO_0006833 water transport The directed movement of water (H2O) by the renal system. http://purl.obolibrary.org/obo/CL_0000075 columnar/cuboidal epithelial cell http://purl.obolibrary.org/obo/CL_0000066 epithelial cell A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube. http://purl.obolibrary.org/obo/GO_0003104 positive regulation of glomerular filtration http://purl.obolibrary.org/obo/GO_0051240 positive regulation of multicellular organismal process Any process that activates or increases the frequency, rate or extent of glomerular filtration. Glomerular filtration is the process whereby blood is filtered by the glomerulus into the renal tubule. http://purl.obolibrary.org/obo/CL_0000076 squamous epithelial cell http://purl.obolibrary.org/obo/CL_0000066 epithelial cell An epithelial cell that has a flattened morphology. http://purl.obolibrary.org/obo/GO_0003105 negative regulation of glomerular filtration http://purl.obolibrary.org/obo/GO_0051241 negative regulation of multicellular organismal process Any process that stops, prevents, or reduces the frequency, rate or extent of glomerular filtration. Glomerular filtration is the process whereby blood is filtered by the glomerulus into the renal tubule. http://purl.obolibrary.org/obo/CL_0000077 mesothelial cell http://purl.obolibrary.org/obo/CL_0002078 meso-epithelial cell A flat, squamous-like epithelial cell of mesodermal origin. It forms the mesothelium, which lines the body's serous cavities including the pleural, peritoneal, and pericardial spaces. This cell plays a crucial role in synthesizing and secreting lubricants, such as glycosaminoglycans and surfactants, which minimize friction between adjacent tissues during movement. http://purl.obolibrary.org/obo/GO_0003131 mesodermal-endodermal cell signaling http://purl.obolibrary.org/obo/GO_0007267 cell-cell signaling Any process that mediates the transfer of information from mesodermal cells to endodermal cells. http://purl.obolibrary.org/obo/CL_0000078 peridermal cell http://purl.obolibrary.org/obo/CL_0000362 epidermal cell Any squamous epithelial cell that is part of some periderm. http://purl.obolibrary.org/obo/CL_0000079 stratified epithelial cell http://purl.obolibrary.org/obo/CL_0000066 epithelial cell An epithelial cell, organized into multiple layers, with only the basal layer being in contact with the basement membrane. http://purl.obolibrary.org/obo/GO_0003133 endodermal-mesodermal cell signaling http://purl.obolibrary.org/obo/GO_0007267 cell-cell signaling Any process that mediates the transfer of information from endodermal cells to mesodermal cells. http://purl.obolibrary.org/obo/CL_0000080 circulating cell http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell A cell which moves among different tissues of the body, via blood, lymph, or other medium. http://purl.obolibrary.org/obo/GO_0003142 cardiogenic plate morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structures of the cardiogenic plate are generated and organized. The cardiogenic plate is the first recognizable structure derived from the heart field. http://purl.obolibrary.org/obo/CL_0000081 blood cell http://purl.obolibrary.org/obo/CL_0000988 hematopoietic cell A cell found predominately in the blood. http://purl.obolibrary.org/obo/CL_0000082 epithelial cell of lung http://purl.obolibrary.org/obo/CL_0002632 epithelial cell of lower respiratory tract An epithelial cell of the lung. http://purl.obolibrary.org/obo/GO_0003143 embryonic heart tube morphogenesis http://purl.obolibrary.org/obo/GO_0060562 epithelial tube morphogenesis The process in which the anatomical structures of the embryonic heart tube are generated and organized. The embryonic heart tube is an epithelial tube that will give rise to the mature heart. http://purl.obolibrary.org/obo/CL_0000083 epithelial cell of pancreas http://purl.obolibrary.org/obo/CL_0002076 endo-epithelial cell An epithelial cell of the pancreas. http://purl.obolibrary.org/obo/GO_0003144 embryonic heart tube formation http://purl.obolibrary.org/obo/GO_0001838 embryonic epithelial tube formation The process that gives rise to the embryonic heart tube. This process pertains to the initial formation of a structure from unspecified parts. The embryonic heart tube is an epithelial tube that will give rise to the mature heart. http://purl.obolibrary.org/obo/CL_0000084 T cell http://purl.obolibrary.org/obo/CL_0000542 lymphocyte A type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex. http://purl.obolibrary.org/obo/GO_0003147 neural crest cell migration involved in heart formation http://purl.obolibrary.org/obo/GO_0060974 cell migration involved in heart formation The characteristic movement of a cell from the dorsal ridge of the neural tube towards the heart and that contributes to heart formation. http://purl.obolibrary.org/obo/CL_0000091 Kupffer cell http://purl.obolibrary.org/obo/CL_0000864 tissue-resident macrophage A tissue-resident macrophage of the reticuloendothelial system found on the luminal surface of the hepatic sinusoids involved in erythrocyte clearance. Markers include F4/80+, CD11b-low, CD68-positive, sialoadhesin-positive, CD163/SRCR-positive. Irregular, with long processes including lamellipodia extending into the sinusoid lumen, have flattened nucleus with cytoplasm containing characteristic invaginations of the plasma membrane (vermiform bodies); lie within the sinusoid lumen attached to the endothelial surface; derived from the bone marrow, form a major part of the body's mononuclear phagocyte system. http://purl.obolibrary.org/obo/GO_0003148 outflow tract septum morphogenesis http://purl.obolibrary.org/obo/GO_0060411 cardiac septum morphogenesis The process in which the anatomical structures of the outflow tract septum are generated and organized. The outflow tract septum is a partition in the outflow tract. http://purl.obolibrary.org/obo/CL_0000092 osteoclast http://purl.obolibrary.org/obo/CL_0001035 bone cell A specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue, which typically differentiates from monocytes. This cell has the following markers: tartrate-resistant acid phosphatase type 5-positive, PU.1-positive, c-fos-positive, nuclear factor NF-kappa-B p100 subunit-positive, tumor necrosis factor receptor superfamily member 11A-positive and macrophage colony-stimulating factor 1 receptor-positive. http://purl.obolibrary.org/obo/GO_0003149 membranous septum morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the membranous septum is generated and organized. The membranous septum is the upper part of ventricular septum. http://purl.obolibrary.org/obo/CL_0000094 granulocyte http://purl.obolibrary.org/obo/CL_0000766 myeloid leukocyte A leukocyte with abundant granules in the cytoplasm. http://purl.obolibrary.org/obo/GO_0003150 muscular septum morphogenesis http://purl.obolibrary.org/obo/GO_0060415 muscle tissue morphogenesis The process in which the muscular septum is generated and organized. The muscular septum is the lower part of the ventricular septum. http://purl.obolibrary.org/obo/CL_0000096 mature neutrophil http://purl.obolibrary.org/obo/CL_0000775 neutrophil A fully differentiated neutrophil, a granular leukocyte having a nucleus with three to five lobes connected by slender threads, and cytoplasm containing fine inconspicuous granules and stainable by neutral dyes. They are produced in bone marrow at a rate of 5e10-10e10/day and have a half-life of 6-8 hours. Neutrophils are CD15-positive, CD16-positive, CD32-positive, CD43-positive, CD181-positive, and CD182-positive. http://purl.obolibrary.org/obo/GO_0003151 outflow tract morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structures of the outflow tract are generated and organized. The outflow tract is the portion of the heart through which blood flows into the arteries. http://purl.obolibrary.org/obo/CL_0000097 mast cell http://purl.obolibrary.org/obo/CL_0002274 histamine secreting cell A cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation. Progenitors leave bone marrow and mature in connective and mucosal tissue. Mature mast cells are found in all tissues, except the bloodstream. Their phenotype is CD117-high, CD123-negative, CD193-positive, CD200R3-positive, and FceRI-high. Stem-cell factor (KIT-ligand; SCF) is the main controlling signal of their survival and development. http://purl.obolibrary.org/obo/GO_0003156 regulation of animal organ formation http://purl.obolibrary.org/obo/GO_2000027 regulation of animal organ morphogenesis Any process that modulates the rate, frequency or extent of animal organ formation. Organ formation is the process pertaining to the initial formation of an organ from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure, such as inductive events, and ends when the structural rudiment of the organ is recognizable, such as a condensation of mesenchymal cells into the organ rudiment. http://purl.obolibrary.org/obo/CL_0000098 sensory epithelial cell http://purl.obolibrary.org/obo/CL_0000197 sensory receptor cell A specialized epithelial cell involved in sensory perception. Restricted to special sense organs of the olfactory, gustatory, and vestibulocochlear receptor systems; contain sensory cells surrounded by supportive, non-receptive cells. http://purl.obolibrary.org/obo/GO_0003157 endocardium development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the endocardium over time, from its formation to the mature structure. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers. http://purl.obolibrary.org/obo/CL_0000099 interneuron http://purl.obolibrary.org/obo/CL_2000029 central nervous system neuron Most generally any neuron which is not motor or sensory. Interneurons may also refer to neurons whose axons remain within a particular brain region as contrasted with projection neurons which have axons projecting to other brain regions. http://purl.obolibrary.org/obo/GO_0003158 endothelium development http://purl.obolibrary.org/obo/GO_0060429 epithelium development The process whose specific outcome is the progression of an endothelium over time, from its formation to the mature structure. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells. http://purl.obolibrary.org/obo/CL_0000100 motor neuron http://purl.obolibrary.org/obo/CL_0000527 efferent neuron An efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes or inhibits movement. http://purl.obolibrary.org/obo/GO_0003159 morphogenesis of an endothelium http://purl.obolibrary.org/obo/GO_0002009 morphogenesis of an epithelium The process in which the anatomical structure of an endothelium is generated and organized. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells. http://purl.obolibrary.org/obo/CL_0000101 sensory neuron http://purl.obolibrary.org/obo/CL_0000526 afferent neuron Any neuron having a sensory function; an afferent neuron conveying sensory impulses. http://purl.obolibrary.org/obo/GO_0003160 endocardium morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structure of the endocardium is generated and organized. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers. http://purl.obolibrary.org/obo/CL_0000102 polymodal neuron http://purl.obolibrary.org/obo/CL_2000032 peripheral nervous system neuron A neuron type that respond to multiple stimuli such as mechanical, thermal and chemical. This neuron type is responsible for integrating different types of sensory inputs, allowing organisms to respond appropriately to diverse environmental challenges. http://purl.obolibrary.org/obo/CL_0000103 bipolar neuron http://purl.obolibrary.org/obo/CL_0000099 interneuron A type of interneuron that has two neurites, usually an axon and a dendrite, extending from opposite poles of an ovoid cell body. http://purl.obolibrary.org/obo/GO_0003161 cardiac conduction system development http://purl.obolibrary.org/obo/GO_0048738 cardiac muscle tissue development The process whose specific outcome is the progression of the cardiac conduction system over time, from its formation to the mature structure. The cardiac conduction system consists of specialized cardiomyocytes that regulate the frequency of heart beat. http://purl.obolibrary.org/obo/CL_0000104 multipolar neuron http://purl.obolibrary.org/obo/CL_2000029 central nervous system neuron A neuron with three or more neurites, usually an axon and multiple dendrites. http://purl.obolibrary.org/obo/GO_0003162 atrioventricular node development http://purl.obolibrary.org/obo/GO_0048738 cardiac muscle tissue development The process whose specific outcome is the progression of the atrioventricular (AV) node over time, from its formation to the mature structure. The AV node is part of the cardiac conduction system that controls the timing of ventricle contraction by receiving electrical signals from the sinoatrial (SA) node and relaying them to the His-Purkinje system. http://purl.obolibrary.org/obo/CL_0000105 pseudounipolar neuron http://purl.obolibrary.org/obo/CL_2000032 peripheral nervous system neuron Neuron with two neurites that are fused grossly when they protrude from the soma and bifurcate a short distance from the soma. http://purl.obolibrary.org/obo/GO_0003163 sinoatrial node development http://purl.obolibrary.org/obo/GO_0003228 atrial cardiac muscle tissue development The process whose specific outcome is the progression of the sinoatrial (SA) node over time, from its formation to the mature structure. The SA node is part of the cardiac conduction system that controls the timing of heart muscle contraction. It relays electrical signals to the AV node. http://purl.obolibrary.org/obo/CL_0000106 unipolar neuron http://purl.obolibrary.org/obo/CL_2000032 peripheral nervous system neuron Neuron with one neurite that extends from the cell body. http://purl.obolibrary.org/obo/GO_0003164 His-Purkinje system development http://purl.obolibrary.org/obo/GO_0003229 ventricular cardiac muscle tissue development The process whose specific outcome is the progression of the His-Purkinje system over time, from its formation to the mature structure. The His-Purkinje system receives signals from the AV node and is composed of the fibers that regulate cardiac muscle contraction in the ventricles. http://purl.obolibrary.org/obo/CL_0000107 autonomic neuron http://purl.obolibrary.org/obo/CL_2000032 peripheral nervous system neuron A neuron whose cell body is within an autonomic ganglion. http://purl.obolibrary.org/obo/GO_0003165 Purkinje myocyte development http://purl.obolibrary.org/obo/GO_0003229 ventricular cardiac muscle tissue development The process whose specific outcome is the progression of a Purkinje myocyte over time, from its formation to the mature structure. The Purkinje myocyte (also known as cardiac Purkinje fiber) is part of the cardiac conduction system that receives signals from the bundle of His and innervates the ventricular cardiac muscle. http://purl.obolibrary.org/obo/CL_0000108 cholinergic neuron http://purl.obolibrary.org/obo/CL_0000540 neuron A neuron that uses acetylcholine as a vesicular neurotransmitter. http://purl.obolibrary.org/obo/GO_0003166 bundle of His development http://purl.obolibrary.org/obo/GO_0003229 ventricular cardiac muscle tissue development The process whose specific outcome is the progression of the bundle of His over time, from its formation to the mature structure. The bundle of His is part of the His-Purkinje system that transmits signals from the AV node to the cardiac Purkinje fibers. http://purl.obolibrary.org/obo/CL_0000110 peptidergic neuron http://purl.obolibrary.org/obo/CL_0000540 neuron A neuron that uses neuropeptides as transmitters. http://purl.obolibrary.org/obo/GO_0003167 atrioventricular bundle cell differentiation http://purl.obolibrary.org/obo/GO_0060932 His-Purkinje system cell differentiation The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell of the atrioventricular bundle. These cells are specialized cardiomyocytes that transmit signals from the AV node to the cardiac Purkinje fibers. http://purl.obolibrary.org/obo/CL_0000112 columnar neuron http://purl.obolibrary.org/obo/CL_0000028 CNS neuron (sensu Nematoda and Protostomia) A neuron of the invertebrate central nervous system. This neuron innervates the central complex (CX) of an invertebrate brain and it forms columnar patterns with its dendrites. It is involved in navigation and spatial processing. http://purl.obolibrary.org/obo/GO_0003168 Purkinje myocyte differentiation http://purl.obolibrary.org/obo/GO_0060932 His-Purkinje system cell differentiation The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a Purkinje myocyte (also known as cardiac Purkinje fiber cell). These cells are specialized cardiomyocytes that receive signals from the bundle of His and innervate the ventricular cardiac muscle. http://purl.obolibrary.org/obo/CL_0000113 mononuclear phagocyte http://purl.obolibrary.org/obo/CL_0000842 mononuclear leukocyte A vertebrate phagocyte with a single nucleus. http://purl.obolibrary.org/obo/GO_0003169 coronary vein morphogenesis http://purl.obolibrary.org/obo/GO_0060977 coronary vasculature morphogenesis The process in which the anatomical structures of veins of the heart are generated and organized. http://purl.obolibrary.org/obo/CL_0000114 surface ectodermal cell http://purl.obolibrary.org/obo/CL_0000221 ectodermal cell An ectodermal cell that is part of the external ectoderm, forming the outermost layer of the developing embryo. It is characterized by its polarized nature, with distinct apical and basal surfaces (Ferrante Jr., Reinke, & Stanley, 1995). Surface ectodermal cell gives rise to the epidermis, hair follicles, nails, sensory organs, and specialized structures like the apical ectodermal ridge crucial for limb development (Skoufa et al., 2024). http://purl.obolibrary.org/obo/GO_0003170 heart valve development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of a heart valve over time, from its formation to the mature structure. A heart valve is a structure that restricts the flow of blood to different regions of the heart and forms from an endocardial cushion. http://purl.obolibrary.org/obo/CL_0000115 endothelial cell http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal. In mammals, endothelial cell has vimentin filaments and is derived from the mesoderm. http://purl.obolibrary.org/obo/GO_0003179 heart valve morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the structure of a heart valve is generated and organized. http://purl.obolibrary.org/obo/CL_0000116 pioneer neuron http://purl.obolibrary.org/obo/CL_0000540 neuron Pioneer neurons establish a pathway in the developing central nervous system and then undergo programmed cell death once the adult axons, which follow them, have made connections with the target site. Thus, they are a transient cell type involved in axon guidance. http://purl.obolibrary.org/obo/GO_0003188 heart valve formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The developmental process pertaining to the initial formation of a heart valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. http://purl.obolibrary.org/obo/CL_0000118 basket cell http://purl.obolibrary.org/obo/CL_0011005 GABAergic interneuron Basket cells are inhibitory GABAergic interneurons of the brain. In general, dendrites of basket cells are free branching and contain smooth spines. Axons are highly branched. The branched axonal arborizations give rise to basket-like structures that surround the soma of the target cell. Basket cells form axo-somatic synapses, meaning their synapses target somas of other cells. http://purl.obolibrary.org/obo/GO_0003197 endocardial cushion development http://purl.obolibrary.org/obo/GO_0060485 mesenchyme development The progression of a cardiac cushion over time, from its initial formation to the mature structure. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves. http://purl.obolibrary.org/obo/CL_0000119 cerebellar Golgi cell http://purl.obolibrary.org/obo/CL_4023057 cerebellar inhibitory GABAergic interneuron Large intrinsic neuron located in the granule layer of the cerebellar cortex that extends its dendrites into the molecular layer where they receive contact from parallel fibers. The axon of the Golgi cell ramifies densely in the granule layer and enters into a complex arrangement with mossy fiber terminals and granule cell dendrites to form the cerebellar glomerulus. Llinas, Walton and Lang. In The Synaptic Organization of the Brain. 5th ed. 2004. http://purl.obolibrary.org/obo/GO_0003203 endocardial cushion morphogenesis http://purl.obolibrary.org/obo/GO_0072132 mesenchyme morphogenesis The process in which the anatomical structure of the endocardial cushion is generated and organized. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves. http://purl.obolibrary.org/obo/CL_0000120 granule cell http://purl.obolibrary.org/obo/CL_2000029 central nervous system neuron A neuron of the vertebrate central nervous system that is small in size. This general class includes small neurons in the granular layer of the cerebellar cortex, cerebral cortex neurons that are not pyramidal cells and small neurons without axons found in the olfactory bulb. http://purl.obolibrary.org/obo/GO_0003204 cardiac skeleton development http://purl.obolibrary.org/obo/GO_0061448 connective tissue development The progression of the cardiac skeleton over time, from its formation to the mature structure. The cardiac skeleton is a specialized extracellular matrix that separates the atria from the ventricles and provides physical support for the heart. http://purl.obolibrary.org/obo/CL_0000121 Purkinje cell http://purl.obolibrary.org/obo/CL_1001611 cerebellar neuron An inhibitory neuron and the sole output neuron of the cerebellar cortex, the Purkinje cell's soma is located between the granular and molecular layers of the cerebellum. It is one of the largest neural cells in the mammalian brain, ranging from 50 to 80 micrometres in diameter. Purkinje cells have planar, fan-shaped dendrites that branch extensively with little overlap. This cell type receives synaptic input from parallel fibres, which modulate high-frequency spike activity known as "simple spikes," and climbing fibres, which modulate infrequent calcium spike activity known as "complex spikes". Purkinje cells are involved in motor coordination, particularly in correcting movements in progress. http://purl.obolibrary.org/obo/CL_0000122 stellate neuron http://purl.obolibrary.org/obo/CL_2000029 central nervous system neuron A neuron that has dendritic processes radiating from the cell body forming a star-like shape. http://purl.obolibrary.org/obo/GO_0003205 cardiac chamber development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of a cardiac chamber over time, from its formation to the mature structure. A cardiac chamber is an enclosed cavity within the heart. http://purl.obolibrary.org/obo/GO_0003206 cardiac chamber morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which a cardiac chamber is generated and organized. A cardiac chamber is an enclosed cavity within the heart. http://purl.obolibrary.org/obo/CL_0000125 glial cell http://purl.obolibrary.org/obo/CL_0000095 neuron associated cell A non-neuronal cell of the nervous system. They not only provide physical support, but also respond to injury, regulate the ionic and chemical composition of the extracellular milieu. Guide neuronal migration during development, and exchange metabolites with neurons. http://purl.obolibrary.org/obo/GO_0003207 cardiac chamber formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The developmental process pertaining to the initial formation of a cardiac chamber from unspecified parts. A cardiac chamber is an enclosed cavity within the heart. http://purl.obolibrary.org/obo/CL_0000126 macroglial cell http://purl.obolibrary.org/obo/CL_0000125 glial cell A neuroglial cell of ectodermal origin, i.e., the astrocytes and oligodendrocytes considered together. http://purl.obolibrary.org/obo/GO_0003208 cardiac ventricle morphogenesis http://purl.obolibrary.org/obo/GO_0003206 cardiac chamber morphogenesis The process in which the cardiac ventricle is generated and organized. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart. http://purl.obolibrary.org/obo/CL_0000127 astrocyte http://purl.obolibrary.org/obo/CL_0000126 macroglial cell A class of large neuroglial (macroglial) cells in the central nervous system - the largest and most numerous neuroglial cells in the brain and spinal cord. Astrocytes (from 'star' cells) are irregularly shaped with many long processes, including those with 'end feet' which form the glial (limiting) membrane and directly and indirectly contribute to the blood-brain barrier. They regulate the extracellular ionic and chemical environment, and 'reactive astrocytes' (along with microglia) respond to injury. http://purl.obolibrary.org/obo/GO_0003209 cardiac atrium morphogenesis http://purl.obolibrary.org/obo/GO_0003206 cardiac chamber morphogenesis The process in which the cardiac atrium is generated and organized. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle. http://purl.obolibrary.org/obo/CL_0000128 oligodendrocyte http://purl.obolibrary.org/obo/CL_4023154 myelinating glial cell A class of large neuroglial (macroglial) cells in the central nervous system. Form the insulating myelin sheath of axons in the central nervous system. http://purl.obolibrary.org/obo/GO_0003210 cardiac atrium formation http://purl.obolibrary.org/obo/GO_0003207 cardiac chamber formation The developmental process pertaining to the initial formation of a cardiac atrium from unspecified parts. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle. http://purl.obolibrary.org/obo/CL_0000129 microglial cell http://purl.obolibrary.org/obo/CL_0000878 central nervous system macrophage A transcriptomically distinct central nervous system macrophage found in the parenchyma of the central nervous system. Marker include CD11b-positive, F4/80-positive, and CD68-positive. http://purl.obolibrary.org/obo/GO_0003211 cardiac ventricle formation http://purl.obolibrary.org/obo/GO_0003207 cardiac chamber formation The developmental process pertaining to the initial formation of a cardiac ventricle from unspecified parts. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart. http://purl.obolibrary.org/obo/CL_0000131 gut endothelial cell http://purl.obolibrary.org/obo/CL_0000115 endothelial cell An endothelial cell that lines the blood and lymphatic vessels of the digestive tract. This cell forms the gut–vascular barrier (GVB) through tight junctions and crosstalk with pericytes and enteric glial cells, regulating the passage of nutrients and immune cells while restricting microbial translocation into the bloodstream. http://purl.obolibrary.org/obo/GO_0003212 cardiac left atrium morphogenesis http://purl.obolibrary.org/obo/GO_0003209 cardiac atrium morphogenesis The process in which the left cardiac atrium is generated and organized. http://purl.obolibrary.org/obo/CL_0000132 corneal endothelial cell http://purl.obolibrary.org/obo/CL_0000115 endothelial cell An hexagonal, flattened, mitochondria-rich endothelial cell that forms a monolayer on the posterior surface of the cornea (the corneal endothelium). Corneal endothelial cells are derived from the neural crest and are responsible for keeping the cornea transparent by maintaining the tissue in a semi-dry state through the action of their ionic pumps and tight junction barrier. http://purl.obolibrary.org/obo/GO_0003213 cardiac right atrium morphogenesis http://purl.obolibrary.org/obo/GO_0003209 cardiac atrium morphogenesis The process in which the right cardiac atrium is generated and organized. http://purl.obolibrary.org/obo/CL_0000133 neurectodermal cell http://purl.obolibrary.org/obo/CL_0000221 ectodermal cell Ectoderm destined to be nervous tissue. http://purl.obolibrary.org/obo/GO_0003214 cardiac left ventricle morphogenesis http://purl.obolibrary.org/obo/GO_0003208 cardiac ventricle morphogenesis The process in which the left cardiac ventricle is generated and organized. http://purl.obolibrary.org/obo/CL_0000134 mesenchymal stem cell http://purl.obolibrary.org/obo/CL_0002320 connective tissue cell A connective tissue cell that normally gives rise to other cells that are organized as three-dimensional masses. In humans, this cell type is CD73-positive, CD90-positive, CD105-positive, CD45-negative, CD34-negative, and MHCII-negative. They may further differentiate into osteoblasts, adipocytes, myocytes, neurons, or chondroblasts in vitro. Originally described as residing in the bone marrow, this cell type is now known to reside in many, if not all, adult organs. http://purl.obolibrary.org/obo/GO_0003215 cardiac right ventricle morphogenesis http://purl.obolibrary.org/obo/GO_0003208 cardiac ventricle morphogenesis The process in which the right cardiac ventricle is generated and organized. http://purl.obolibrary.org/obo/CL_0000135 circulating fibrocyte http://purl.obolibrary.org/obo/CL_0011026 progenitor cell A bone marrow-derived cell that predominantly develops from myeloid lineage-restricted progenitor cells and circulates in peripheral blood, characterized by co-expression of hematopoietic markers CD45 and CD34 along with stromal markers including collagen type I in both humans and mice (Chesney et al., 1997; Blakaj and Bucala, 2012). This spindle-shaped cell exhibits a unique dual identity, functionally bridging immune and stromal compartments with characteristics of both monocytes and fibroblasts. Predominantly arising from circulating monocytes, it migrates to injury sites via chemokine receptors and participates in wound repair through extracellular matrix deposition, cytokine secretion, and antigen presentation via MHC class II. As mesenchymal progenitors, fibrocytes can differentiate into fibroblasts, myofibroblasts, and adipocytes, contributing to both physiological repair and pathological fibrosis (Blakaj and Bucala, 2012). http://purl.obolibrary.org/obo/GO_0003216 cardiac left atrium formation http://purl.obolibrary.org/obo/GO_0003210 cardiac atrium formation The developmental process pertaining to the initial formation of a left cardiac atrium from unspecified parts. http://purl.obolibrary.org/obo/CL_0000136 adipocyte http://purl.obolibrary.org/obo/CL_0002320 connective tissue cell A fat-storing cell found mostly in the abdominal cavity and subcutaneous tissue of mammals. Fat is usually stored in the form of triglycerides. http://purl.obolibrary.org/obo/GO_0003217 cardiac right atrium formation http://purl.obolibrary.org/obo/GO_0003210 cardiac atrium formation The developmental process pertaining to the initial formation of a cardiac right atrium from unspecified parts. http://purl.obolibrary.org/obo/CL_0000137 osteocyte http://purl.obolibrary.org/obo/CL_0002320 connective tissue cell A mature osteoblast that has become embedded in the bone matrix. They occupy a small cavity, called lacuna, in the matrix and are connected to adjacent osteocytes via protoplasmic projections called canaliculi. http://purl.obolibrary.org/obo/GO_0003218 cardiac left ventricle formation http://purl.obolibrary.org/obo/GO_0003211 cardiac ventricle formation The developmental process pertaining to the initial formation of a left cardiac ventricle from unspecified parts. http://purl.obolibrary.org/obo/CL_0000138 chondrocyte http://purl.obolibrary.org/obo/CL_0007001 skeletogenic cell A skeletogenic cell that secretes a specialized, avascular, GAG-rich matrix, is embedded in cartilage tissue matrix, retains the ability to divide, and develops from a chondroblast cell. http://purl.obolibrary.org/obo/GO_0003219 cardiac right ventricle formation http://purl.obolibrary.org/obo/GO_0003211 cardiac ventricle formation The developmental process pertaining to the initial formation of a right cardiac ventricle from unspecified parts. http://purl.obolibrary.org/obo/CL_0000140 odontocyte http://purl.obolibrary.org/obo/CL_0002320 connective tissue cell Skeletogenic cell that secretes dentine matrix, is derived from odontogenic papilla. Embedded in dentine tissue, and is the transformation of a non-terminally differentiated odontoblast cell. http://purl.obolibrary.org/obo/GO_0003220 left ventricular cardiac muscle tissue morphogenesis http://purl.obolibrary.org/obo/GO_0055010 ventricular cardiac muscle tissue morphogenesis The process in which the anatomical structures of left cardiac ventricle muscle are generated and organized. http://purl.obolibrary.org/obo/CL_0000141 cementocyte http://purl.obolibrary.org/obo/CL_0000137 osteocyte An osteocytelike cell with numerous processes, trapped in a lacuna in the cement of the tooth. http://purl.obolibrary.org/obo/CL_0000142 hyalocyte http://purl.obolibrary.org/obo/CL_0000499 stromal cell A cell occurring in the peripheral part of the vitreous body of the eye that may be responsible for production of hyaluronic acid and collagen. http://purl.obolibrary.org/obo/GO_0003221 right ventricular cardiac muscle tissue morphogenesis http://purl.obolibrary.org/obo/GO_0055010 ventricular cardiac muscle tissue morphogenesis The process in which the anatomical structures of the right cardiac ventricle muscle are generated and organized. http://purl.obolibrary.org/obo/CL_0000145 professional antigen presenting cell http://purl.obolibrary.org/obo/CL_0000738 leukocyte A cell capable of processing and presenting lipid and protein antigens to T cells in order to initiate an immune response. http://purl.obolibrary.org/obo/GO_0003222 ventricular trabecula myocardium morphogenesis http://purl.obolibrary.org/obo/GO_0061384 heart trabecula morphogenesis The process in which the anatomical structures of the trabecular cardiac ventricle muscle are generated and organized. http://purl.obolibrary.org/obo/CL_0000147 pigment cell http://purl.obolibrary.org/obo/CL_0000325 stuff accumulating cell A pigment cell is a cell that contains pigment granules. http://purl.obolibrary.org/obo/GO_0003225 left ventricular trabecular myocardium morphogenesis http://purl.obolibrary.org/obo/GO_0003222 ventricular trabecula myocardium morphogenesis The process in which the anatomical structures of cardiac left ventricular trabecular myocardium are generated and organized. http://purl.obolibrary.org/obo/CL_0000148 melanocyte http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell A pigment cell derived from the neural crest. Contains melanin-filled pigment granules, which gives a brown to black appearance. http://purl.obolibrary.org/obo/GO_0003227 right ventricular trabecular myocardium morphogenesis http://purl.obolibrary.org/obo/GO_0003222 ventricular trabecula myocardium morphogenesis The process in which the anatomical structures of the right ventricular myocardium are generated and organized. http://purl.obolibrary.org/obo/CL_0000150 glandular secretory epithelial cell http://purl.obolibrary.org/obo/CL_1100001 secretory epithelial cell An epithelial cell, located in a gland, that is specialised for the synthesis and secretion of specific biomolecules, such as hormones, or mucous. http://purl.obolibrary.org/obo/GO_0003228 atrial cardiac muscle tissue development http://purl.obolibrary.org/obo/GO_0048738 cardiac muscle tissue development The process whose specific outcome is the progression of cardiac muscle of the atrium over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/CL_0000151 secretory cell http://purl.obolibrary.org/obo/CL_0000000 cell A cell that specializes in controlled release of one or more substances. http://purl.obolibrary.org/obo/GO_0003229 ventricular cardiac muscle tissue development http://purl.obolibrary.org/obo/GO_0048738 cardiac muscle tissue development The process whose specific outcome is the progression of ventricular cardiac muscle over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/CL_0000152 exocrine cell http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell A cell of an exocrine gland; i.e. a gland that discharges its secretion via a duct. http://purl.obolibrary.org/obo/GO_0003230 cardiac atrium development http://purl.obolibrary.org/obo/GO_0003205 cardiac chamber development The process whose specific outcome is the progression of a cardiac atrium over time, from its formation to the mature structure. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle. http://purl.obolibrary.org/obo/CL_0000153 glycosaminoglycan secreting cell http://purl.obolibrary.org/obo/CL_0000447 carbohydrate secreting cell A cell that secretes glycosaminoglycans. http://purl.obolibrary.org/obo/GO_0003231 cardiac ventricle development http://purl.obolibrary.org/obo/GO_0003205 cardiac chamber development The process whose specific outcome is the progression of a cardiac ventricle over time, from its formation to the mature structure. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart. http://purl.obolibrary.org/obo/CL_0000154 protein secreting cell http://purl.obolibrary.org/obo/CL_0000151 secretory cell Any secretory cell that is capable of some protein secretion. http://purl.obolibrary.org/obo/GO_0003235 sinus venosus development http://purl.obolibrary.org/obo/GO_0003205 cardiac chamber development The progression of the sinus venosus over time, from its formation to the mature structure. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart. http://purl.obolibrary.org/obo/CL_0000155 peptic cell http://purl.obolibrary.org/obo/CL_0002659 glandular epithelial cell of stomach An epithelial cell of the stomach that is part of the fundic gastric gland. This cell is characterized by a basally located nucleus, abundant rough endoplasmic reticulum, and large apical secretory granules. It produces and secretes pepsinogen, the inactive precursor of the digestive enzyme pepsin. http://purl.obolibrary.org/obo/GO_0003236 sinus venosus morphogenesis http://purl.obolibrary.org/obo/GO_0003206 cardiac chamber morphogenesis The process in which the sinus venosus is generated and organized. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart. http://purl.obolibrary.org/obo/CL_0000157 surfactant secreting cell http://purl.obolibrary.org/obo/CL_0000151 secretory cell A cell that specializes in secretion of surfactant in the alveoli of the lung. http://purl.obolibrary.org/obo/GO_0003237 sinus venosus formation http://purl.obolibrary.org/obo/GO_0003207 cardiac chamber formation The developmental process pertaining to the initial formation of the sinus venosus from unspecified parts. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart. http://purl.obolibrary.org/obo/CL_0000158 club cell http://purl.obolibrary.org/obo/CL_0008055 respiratory tract secretory epithelial cell A non-mucous, epithelial secretory cell that is part of the tracheobronchial tree. A club cell has short microvilli but no cilia. A club cell is able to multiply and differentiate into ciliated cells to regenerate the bronchiolar epithelium and it also protects the tracheobronchial epithelium. http://purl.obolibrary.org/obo/GO_0003241 growth involved in heart morphogenesis http://purl.obolibrary.org/obo/GO_0060560 developmental growth involved in morphogenesis Developmental growth that contributes to the shaping of the heart. http://purl.obolibrary.org/obo/CL_0000160 goblet cell http://purl.obolibrary.org/obo/CL_0000319 mucus secreting cell A specialized, columnar, mucus secreting epithelial cell shaped like a flask or goblet. A narrow basal end contains the nucleus while the apical end is swollen by the accumulation of mucus laden secretory granules. Short microvilli project from the apical plasma membrane. http://purl.obolibrary.org/obo/GO_0003245 cardiac muscle tissue growth involved in heart morphogenesis http://purl.obolibrary.org/obo/GO_0055017 cardiac muscle tissue growth The developmental growth of cardiac muscle tissue that contributes to the shaping of the heart. http://purl.obolibrary.org/obo/CL_0000162 parietal cell http://purl.obolibrary.org/obo/CL_0002659 glandular epithelial cell of stomach An epithelial cell of the stomach that is part of the fundic gastric gland. This cell is characterized by its pyramidal shape, abundant mitochondria, and a complex network of secretory canaliculi lined with microvilli. It secretes hydrochloric acid into the stomach lumen and produces intrinsic factor, essential for vitamin B12 absorption. http://purl.obolibrary.org/obo/GO_0003248 heart capillary growth http://purl.obolibrary.org/obo/GO_0048589 developmental growth The increase in heart capillaries that accompanies physiological hypertrophy of cardiac muscle. http://purl.obolibrary.org/obo/CL_0000163 endocrine cell http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell A cell of an endocrine gland, ductless glands that secrete substances which are released directly into the circulation and which influence metabolism and other body functions. http://purl.obolibrary.org/obo/GO_0003253 cardiac neural crest cell migration involved in outflow tract morphogenesis http://purl.obolibrary.org/obo/GO_0060973 cell migration involved in heart development The orderly movement of a neural crest cell from one site to another that will contribute to the morphogenesis of the outflow tract. http://purl.obolibrary.org/obo/CL_0000164 enteroendocrine cell http://purl.obolibrary.org/obo/CL_0000163 endocrine cell An endocrine cell that is located in the epithelium of the gastrointestinal tract or in the pancreas. http://purl.obolibrary.org/obo/CL_0000165 neuroendocrine cell http://purl.obolibrary.org/obo/CL_0000710 neurecto-epithelial cell A neuron that is capable of some hormone secretion in response to neuronal signals. http://purl.obolibrary.org/obo/GO_0003254 regulation of membrane depolarization http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that modulates the rate, frequency or extent of membrane depolarization. Membrane depolarization is the process in which membrane potential changes in the depolarizing direction from the resting potential, usually from negative to positive. http://purl.obolibrary.org/obo/CL_0000166 chromaffin cell http://purl.obolibrary.org/obo/CL_0000568 amine precursor uptake and decarboxylation cell A cell that stores epinephrine secretory vesicles. During times of stress, the nervous system signals the vesicles to secrete their hormonal content. Their name derives from their ability to stain a brownish color with chromic salts. Characteristically, they are located in the adrenal medulla and paraganglia of the sympathetic nervous system. http://purl.obolibrary.org/obo/GO_0003260 cardioblast migration http://purl.obolibrary.org/obo/GO_0060974 cell migration involved in heart formation The orderly movement of a cardiac progenitor cell to form the heart field. Cardiac progenitor cells are non-terminally differentiated, mesoderm-derived cells that are committed to differentiate into cells of the heart. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. http://purl.obolibrary.org/obo/CL_0000167 peptide hormone secreting cell http://purl.obolibrary.org/obo/CL_0000151 secretory cell Any secretory cell that is capable of some peptide hormone secretion. http://purl.obolibrary.org/obo/GO_0003272 endocardial cushion formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The developmental process pertaining to the initial formation of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves. http://purl.obolibrary.org/obo/CL_0000168 insulin secreting cell http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell Any secretory cell that is capable of some insulin secretion. http://purl.obolibrary.org/obo/GO_0003273 cell migration involved in endocardial cushion formation http://purl.obolibrary.org/obo/GO_0060973 cell migration involved in heart development The orderly movement of a cell from one site to another that will contribute to the formation of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves. http://purl.obolibrary.org/obo/CL_0000169 type B pancreatic cell http://purl.obolibrary.org/obo/CL_0008024 pancreatic endocrine cell A cell that secretes insulin and is located towards the center of the islets of Langerhans. http://purl.obolibrary.org/obo/GO_0003274 endocardial cushion fusion http://purl.obolibrary.org/obo/GO_0098609 cell-cell adhesion The cell-cell adhesion process of mesenchymal cardiac cushion cells that contributes to the process of cushion shaping. http://purl.obolibrary.org/obo/CL_0000170 glucagon secreting cell http://purl.obolibrary.org/obo/CL_0000167 peptide hormone secreting cell A cell that secretes glucagon. http://purl.obolibrary.org/obo/GO_0003275 apoptotic process involved in outflow tract morphogenesis http://purl.obolibrary.org/obo/GO_0003278 apoptotic process involved in heart morphogenesis Any apoptotic process that contributes to the shaping of the outflow tract. The outflow tract is the portion of the heart through which blood flows into the arteries. http://purl.obolibrary.org/obo/CL_0000171 pancreatic A cell http://purl.obolibrary.org/obo/CL_0008024 pancreatic endocrine cell A type A enteroendocrine cell found in the periphery of the islets of Langerhans that secretes glucagon. http://purl.obolibrary.org/obo/GO_0003277 apoptotic process involved in endocardial cushion morphogenesis http://purl.obolibrary.org/obo/GO_0003278 apoptotic process involved in heart morphogenesis Any apoptotic process that contributes to the shaping of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves. http://purl.obolibrary.org/obo/CL_0000172 somatostatin secreting cell http://purl.obolibrary.org/obo/CL_0000167 peptide hormone secreting cell Any secretory cell that is capable of some somatostatin secretion. http://purl.obolibrary.org/obo/GO_0003278 apoptotic process involved in heart morphogenesis http://purl.obolibrary.org/obo/GO_0060561 apoptotic process involved in morphogenesis Any apoptotic process that contributes to the shaping of the heart. http://purl.obolibrary.org/obo/CL_0000173 pancreatic D cell http://purl.obolibrary.org/obo/CL_0008024 pancreatic endocrine cell A D cell located in the pancreas. Peripherally placed within the islets like type A cells; contains somatostatin. http://purl.obolibrary.org/obo/GO_0003279 cardiac septum development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of a cardiac septum over time, from its initial formation to the mature structure. http://purl.obolibrary.org/obo/CL_0000174 steroid hormone secreting cell http://purl.obolibrary.org/obo/CL_0000151 secretory cell Any secretory cell that is capable of some steroid hormone secretion. http://purl.obolibrary.org/obo/GO_0003281 ventricular septum development http://purl.obolibrary.org/obo/GO_0003279 cardiac septum development The progression of the ventricular septum over time from its formation to the mature structure. http://purl.obolibrary.org/obo/CL_0000175 luteal cell http://purl.obolibrary.org/obo/CL_0000179 progesterone secreting cell A progesterone secreting cell in the corpus luteum. The large luteal cells develop from the granulosa cells. The small luteal cells develop from the theca cells. http://purl.obolibrary.org/obo/GO_0003283 atrial septum development http://purl.obolibrary.org/obo/GO_0003279 cardiac septum development The progression of the atrial septum over time, from its initial formation to the mature structure. http://purl.obolibrary.org/obo/CL_0000176 ecdysteroid secreting cell http://purl.obolibrary.org/obo/CL_0000174 steroid hormone secreting cell Any secretory cell that is capable of some ecdysteroid secretion. http://purl.obolibrary.org/obo/GO_0003292 cardiac septum cell differentiation http://purl.obolibrary.org/obo/GO_0035051 cardiocyte differentiation The process in which an endocardial cushion cell becomes a cell of a cardiac septum. http://purl.obolibrary.org/obo/CL_0000177 testosterone secreting cell http://purl.obolibrary.org/obo/CL_0000151 secretory cell Any secretory cell that is capable of some testosterone secretion. http://purl.obolibrary.org/obo/GO_0003293 heart valve cell differentiation http://purl.obolibrary.org/obo/GO_0035051 cardiocyte differentiation The process in which an endocardial cushion cell give rise to a cell that is part of a heart valve. http://purl.obolibrary.org/obo/CL_0000178 Leydig cell http://purl.obolibrary.org/obo/CL_0000177 testosterone secreting cell A Leydig cell is a testosterone-secreting cell in the interstitial area, between the seminiferous tubules, in the testis. http://purl.obolibrary.org/obo/GO_0003298 physiological muscle hypertrophy http://purl.obolibrary.org/obo/GO_0014896 muscle hypertrophy The enlargement or overgrowth of all or part of a muscle organ or tissue due to an increase in the size of its muscle cells. Physiological hypertrophy is a normal process during development. http://purl.obolibrary.org/obo/GO_0003300 cardiac muscle hypertrophy http://purl.obolibrary.org/obo/GO_0014897 striated muscle hypertrophy The enlargement or overgrowth of all or part of the heart muscle due to an increase in size of cardiac muscle cells without cell division. http://purl.obolibrary.org/obo/CL_0000179 progesterone secreting cell http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell Any secretory cell that is capable of some progesterone secretion. http://purl.obolibrary.org/obo/CL_0000180 estradiol secreting cell http://purl.obolibrary.org/obo/CL_0000174 steroid hormone secreting cell A steroid hormone secreting cell that secretes estradiol. http://purl.obolibrary.org/obo/GO_0003301 physiological cardiac muscle hypertrophy http://purl.obolibrary.org/obo/GO_0003300 cardiac muscle hypertrophy The enlargement or overgrowth of all or part of the heart muscle due to an increase in size of cardiac muscle cells without cell division. This process contributes to the developmental growth of the heart. http://purl.obolibrary.org/obo/CL_0000182 hepatocyte http://purl.obolibrary.org/obo/CL_0000417 endopolyploid cell The main structural component of the liver. They are specialized epithelial cells that are organized into interconnected plates called lobules. Majority of cell population of liver, polygonal in shape, arranged in plates or trabeculae between sinusoids; may have single nucleus or binucleated. http://purl.obolibrary.org/obo/CL_0000183 contractile cell http://purl.obolibrary.org/obo/CL_0000000 cell A cell whose primary function is to shorten. http://purl.obolibrary.org/obo/GO_0003309 type B pancreatic cell differentiation http://purl.obolibrary.org/obo/GO_0035883 enteroendocrine cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features of a type B pancreatic cell. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin. http://purl.obolibrary.org/obo/CL_0000185 myoepithelial cell http://purl.obolibrary.org/obo/CL_0000183 contractile cell Contractile cells resembling smooth muscle cells that are present in glands, notably the mammary gland, and aid in secretion. This cell has long weaving dendritic processes containing myofilament. http://purl.obolibrary.org/obo/CL_0000186 myofibroblast cell http://purl.obolibrary.org/obo/CL_0002320 connective tissue cell An animal cell that has characteristics of both a fibroblast cell and a smooth muscle cell. http://purl.obolibrary.org/obo/GO_0003310 pancreatic A cell differentiation http://purl.obolibrary.org/obo/GO_0035883 enteroendocrine cell differentiation The process in which relatively unspecialized cells acquire specialized structural and functional features of a pancreatic A cell. A pancreatic A cell is a cell in the pancreas that secretes glucagon. http://purl.obolibrary.org/obo/CL_0000187 muscle cell http://purl.obolibrary.org/obo/CL_0000393 electrically responsive cell A mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns. http://purl.obolibrary.org/obo/CL_0000188 cell of skeletal muscle http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell A somatic cell located in skeletal muscle. http://purl.obolibrary.org/obo/GO_0003311 pancreatic D cell differentiation http://purl.obolibrary.org/obo/GO_7770025 intestinal type D enteroendocrine cell differentiation The process in which relatively unspecialized cells acquire specialized structural and functional features that characterize a pancreatic delta cell. A delta cell is a cell of the pancreas that produces somatostatin. http://purl.obolibrary.org/obo/CL_0000189 slow muscle cell http://purl.obolibrary.org/obo/CL_0008046 extrafusal muscle fiber A muscle cell that develops tension more slowly than a fast-twitch fiber. http://purl.obolibrary.org/obo/CL_0000190 fast muscle cell http://purl.obolibrary.org/obo/CL_0008046 extrafusal muscle fiber A muscle cell that can develop high tension rapidly. It is usually innervated by a single alpha neuron. http://purl.obolibrary.org/obo/GO_0003312 pancreatic PP cell differentiation http://purl.obolibrary.org/obo/GO_0035883 enteroendocrine cell differentiation The process in which relatively unspecialized cells acquire specialized structural and functional features of a pancreatic polypeptide-producing cell. A pancreatic polypeptide-producing cell is a cell in the pancreas that produces pancreatic polypeptide. http://purl.obolibrary.org/obo/CL_0000192 smooth muscle cell http://purl.obolibrary.org/obo/CL_0008007 visceral muscle cell A non-striated, elongated, spindle-shaped cell found lining the digestive tract, uterus, and blood vessels. They develop from specialized myoblasts (smooth muscle myoblast). http://purl.obolibrary.org/obo/CL_0000193 cardiac muscle cell (sensu Arthopoda) http://purl.obolibrary.org/obo/CL_0000746 cardiac muscle cell A striated muscle cell of an arthropod heart that participates in heart contraction. http://purl.obolibrary.org/obo/GO_0003313 heart rudiment development http://purl.obolibrary.org/obo/GO_0060429 epithelium development The progression of the heart rudiment over time, from its initial formation to the mature structure. The heart rudiment is a cone-like structure that is formed when myocardial progenitor cells of the heart field fuse at the midline. The heart rudiment is the first structure of the heart tube. http://purl.obolibrary.org/obo/CL_0000196 insect flight muscle cell http://purl.obolibrary.org/obo/CL_0008003 somatic muscle myotube A muscle cell that is involved in the mechanism of insect flight. This encompasses both, cells that power flight and cells that control flight. http://purl.obolibrary.org/obo/GO_0003314 heart rudiment morphogenesis http://purl.obolibrary.org/obo/GO_0048598 embryonic morphogenesis The process in which the anatomical structures of the heart rudiment are generated and organized. http://purl.obolibrary.org/obo/CL_0000197 sensory receptor cell http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell A cell that is capable of detection of a stimulus involved in sensory perception. http://purl.obolibrary.org/obo/CL_0000198 pain receptor cell http://purl.obolibrary.org/obo/CL_0000006 neuronal receptor cell The peripheral receptor for pain. Includes receptors which are sensitive to painful mechanical stimuli, extreme heat or cold, and chemical stimuli. All mammalian nociceptors are free nerve endings. http://purl.obolibrary.org/obo/GO_0003315 heart rudiment formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The developmental process pertaining to the initial formation of the heart rudiment. http://purl.obolibrary.org/obo/CL_0000199 mechanoreceptor cell http://purl.obolibrary.org/obo/CL_0000101 sensory neuron A cell specialized to transduce mechanical stimuli and relay that information centrally in the nervous system. http://purl.obolibrary.org/obo/CL_0000200 touch receptor cell http://purl.obolibrary.org/obo/CL_0000199 mechanoreceptor cell Any neuron that is capable of some detection of mechanical stimulus involved in sensory perception of touch. http://purl.obolibrary.org/obo/GO_0003322 pancreatic A cell development http://purl.obolibrary.org/obo/GO_0002064 epithelial cell development The process whose specific outcome is the progression of a pancreatic A cell over time, from its formation to the mature structure. A pancreatic A cell is a cell in the pancreas that secretes glucagon. http://purl.obolibrary.org/obo/CL_0000202 auditory hair cell http://purl.obolibrary.org/obo/CL_0000855 sensory hair cell A mechanoreceptor cell of the auditory or vestibular system that is sensitive to auditory stimuli. The accessory sensory structures are arranged so that appropriate stimuli cause movement of the hair-like projections (stereocilia and kinocilia) which relay the information centrally in the nervous system. http://purl.obolibrary.org/obo/CL_0000203 gravity sensitive cell http://purl.obolibrary.org/obo/CL_0000199 mechanoreceptor cell Any neuronal receptor cell that is capable of some detection of mechanical stimulus involved in sensory perception. http://purl.obolibrary.org/obo/GO_0003323 type B pancreatic cell development http://purl.obolibrary.org/obo/GO_0002064 epithelial cell development The process whose specific outcome is the progression of a type B pancreatic cell over time, from its formation to the mature structure. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin. http://purl.obolibrary.org/obo/CL_0000205 thermoreceptor cell http://purl.obolibrary.org/obo/CL_0000006 neuronal receptor cell A cellular receptor which mediates the sense of temperature. Thermoreceptor cells in vertebrates are mostly located under the skin. In mammals there are separate types of thermoreceptors for cold and for warmth and pain receptor cells which detect cold or heat extreme enough to cause pain. http://purl.obolibrary.org/obo/CL_0000206 chemoreceptor cell http://purl.obolibrary.org/obo/CL_0000197 sensory receptor cell A cell specialized to detect chemical substances and relay that information centrally in the nervous system. Chemoreceptors may monitor external stimuli, as in taste and olfaction, or internal stimuli, such as the concentrations of oxygen and carbon dioxide in the blood. http://purl.obolibrary.org/obo/GO_0003324 pancreatic D cell development http://purl.obolibrary.org/obo/GO_0048666 neuron development The process whose specific outcome is the progression of a pancreatic delta cell over time, from its formation to the mature structure. A delta cell is a cell of the pancreas that produces somatostatin. http://purl.obolibrary.org/obo/CL_0000207 olfactory receptor cell http://purl.obolibrary.org/obo/CL_0000206 chemoreceptor cell Any neuron that is capable of some detection of chemical stimulus involved in sensory perception of smell. http://purl.obolibrary.org/obo/CL_0000209 taste receptor cell http://purl.obolibrary.org/obo/CL_0002076 endo-epithelial cell A specialized cell involved in gustatory sensory perception. http://purl.obolibrary.org/obo/GO_0003325 pancreatic PP cell development http://purl.obolibrary.org/obo/GO_0002064 epithelial cell development The process whose specific outcome is the progression of a pancreatic PP cell over time, from its formation to the mature structure. A pancreatic polypeptide-producing cell is a cell in the pancreas that produces pancreatic polypeptide. http://purl.obolibrary.org/obo/CL_0000210 photoreceptor cell http://purl.obolibrary.org/obo/CL_0000101 sensory neuron A cell specialized in detecting light stimuli that are involved in visual perception. http://purl.obolibrary.org/obo/CL_0000211 electrically active cell http://purl.obolibrary.org/obo/CL_0000000 cell A cell whose function is determined by the generation or the reception of an electric signal. http://purl.obolibrary.org/obo/GO_0003330 regulation of extracellular matrix constituent secretion http://purl.obolibrary.org/obo/GO_1903530 regulation of secretion by cell Any process that modulates the rate, frequency, or extent of the controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell or a group of cells. http://purl.obolibrary.org/obo/CL_0000214 synovial cell http://purl.obolibrary.org/obo/CL_0002078 meso-epithelial cell A cell located in the synovial joint. http://purl.obolibrary.org/obo/CL_0000216 Sertoli cell http://purl.obolibrary.org/obo/CL_0002625 seminiferous tubule epithelial cell A supporting cell projecting inward from the basement membrane of seminiferous tubules. They surround and nourish the developing male germ cells and secrete androgen binding protein. Their tight junctions with the spermatogonia and spermatocytes provide a blood-testis barrier. http://purl.obolibrary.org/obo/GO_0003331 positive regulation of extracellular matrix constituent secretion http://purl.obolibrary.org/obo/GO_1903532 positive regulation of secretion by cell Any process that increases the rate, frequency, or extent of the controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell or a group of cells. http://purl.obolibrary.org/obo/CL_0000218 myelinating Schwann cell http://purl.obolibrary.org/obo/CL_4023154 myelinating glial cell A neuroglial cell of the peripheral nervous system which forms the insulating myelin sheaths of peripheral axons. http://purl.obolibrary.org/obo/CL_0000219 motile cell http://purl.obolibrary.org/obo/CL_0000000 cell A cell that moves by its own activities. http://purl.obolibrary.org/obo/GO_0003332 negative regulation of extracellular matrix constituent secretion http://purl.obolibrary.org/obo/GO_1903531 negative regulation of secretion by cell Any process that decreases the rate, frequency, or extent the controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell or a group of cells. http://purl.obolibrary.org/obo/CL_0000221 ectodermal cell http://purl.obolibrary.org/obo/CL_0002321 embryonic cell (metazoa) A cell of the outer of the three germ layers of the embryo. http://purl.obolibrary.org/obo/CL_0000222 mesodermal cell http://purl.obolibrary.org/obo/CL_0002321 embryonic cell (metazoa) A cell of the middle germ layer of the embryo. http://purl.obolibrary.org/obo/GO_0003333 amino acid transmembrane transport http://purl.obolibrary.org/obo/GO_0006865 amino acid transport The process in which an amino acid is transported across a membrane. http://purl.obolibrary.org/obo/CL_0000223 endodermal cell http://purl.obolibrary.org/obo/CL_0002321 embryonic cell (metazoa) A cell of the inner of the three germ layers of the embryo. http://purl.obolibrary.org/obo/CL_0000225 anucleate cell http://purl.obolibrary.org/obo/CL_0000000 cell A cell that lacks a nucleus. http://purl.obolibrary.org/obo/GO_0003334 keratinocyte development http://purl.obolibrary.org/obo/GO_0002064 epithelial cell development The process whose specific outcome is the progression of a keratinocyte over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/CL_0000226 single nucleate cell http://purl.obolibrary.org/obo/CL_0002242 nucleate cell A cell with a single nucleus. http://purl.obolibrary.org/obo/GO_0003335 corneocyte development http://purl.obolibrary.org/obo/GO_0048468 cell development The process whose specific outcome is the progression of the corneocyte over time, from its formation to the mature structure. A corneocyte is the last stage of development of a keratinocyte where the keratinocyte flattens, loses its nucleus and eventually delaminates from the epidermis. http://purl.obolibrary.org/obo/CL_0000227 binucleate cell http://purl.obolibrary.org/obo/CL_0000228 multinucleate cell Any cell that has characteristic some binucleate. http://purl.obolibrary.org/obo/CL_0000228 multinucleate cell http://purl.obolibrary.org/obo/CL_0002242 nucleate cell A cell with more than one nucleus. http://purl.obolibrary.org/obo/GO_0003337 mesenchymal to epithelial transition involved in metanephros morphogenesis http://purl.obolibrary.org/obo/GO_0060231 mesenchymal to epithelial transition A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros. http://purl.obolibrary.org/obo/CL_0000232 erythrocyte http://purl.obolibrary.org/obo/CL_0000764 erythroid lineage cell A red blood cell. In mammals, mature erythrocytes are biconcave disks containing hemoglobin whose function is to transport oxygen. http://purl.obolibrary.org/obo/CL_0000233 platelet http://purl.obolibrary.org/obo/CL_0000763 myeloid cell A non-nucleated disk-shaped cell formed by extrusion from megakaryocytes, found in the blood of all mammals, and mainly involved in blood coagulation. http://purl.obolibrary.org/obo/GO_0003338 metanephros morphogenesis http://purl.obolibrary.org/obo/GO_0060993 kidney morphogenesis The process in which the anatomical structures of the metanephros are generated and organized. http://purl.obolibrary.org/obo/CL_0000234 phagocyte http://purl.obolibrary.org/obo/CL_0000325 stuff accumulating cell Any cell capable of ingesting particulate matter via phagocytosis. http://purl.obolibrary.org/obo/CL_0000235 macrophage http://purl.obolibrary.org/obo/CL_0000766 myeloid leukocyte A mononuclear phagocyte present in variety of tissues, typically differentiated from monocytes, capable of phagocytosing a variety of extracellular particulate material, including immune complexes, microorganisms, and dead cells. http://purl.obolibrary.org/obo/GO_0003339 regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis http://purl.obolibrary.org/obo/GO_2000696 regulation of epithelial cell differentiation involved in kidney development Any process that modulates the rate, frequency or extent of the transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros. http://purl.obolibrary.org/obo/CL_0000236 B cell http://purl.obolibrary.org/obo/CL_0000945 lymphocyte of B lineage A lymphocyte of B lineage that is capable of B cell mediated immunity. http://purl.obolibrary.org/obo/CL_0000239 brush border epithelial cell http://purl.obolibrary.org/obo/CL_0000075 columnar/cuboidal epithelial cell An epithelial cell characterized by the presence of a brush border on its apical surface, which increases the surface area for absorption. http://purl.obolibrary.org/obo/GO_0003340 negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis http://purl.obolibrary.org/obo/GO_2000697 negative regulation of epithelial cell differentiation involved in kidney development Any process that decreases the rate, frequency or extent of the transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros. http://purl.obolibrary.org/obo/CL_0000240 stratified squamous epithelial cell http://purl.obolibrary.org/obo/CL_0000079 stratified epithelial cell A stratified epithelial cell that is part of squamous epithelium, characterized by multiple layers of cells. The basal layer is directly attached to the basement membrane and the apical layer consists of flattened squamous cells. This provides a protective barrier, commonly found in areas subject to abrasion, such as the skin, oral cavity, and esophagus. http://purl.obolibrary.org/obo/CL_0000241 stratified cuboidal epithelial cell http://purl.obolibrary.org/obo/CL_0000079 stratified epithelial cell A stratified epithelial cell that is part of cuboidal epithelium, characterized by multiple layers of cuboidal cells forming the apical layer. This provides a protective lining for ducts in large glands, such as sweat glands. http://purl.obolibrary.org/obo/GO_0003341 cilium movement http://purl.obolibrary.org/obo/GO_0007018 microtubule-based movement The directed, self-propelled movement of a cilium. http://purl.obolibrary.org/obo/GO_0003342 proepicardium development http://purl.obolibrary.org/obo/GO_0060485 mesenchyme development The progression of the proepicardium from its formation to the mature structure. The proepicardium is an outpouching of the septum transversum. http://purl.obolibrary.org/obo/GO_0003343 septum transversum development http://purl.obolibrary.org/obo/GO_0060485 mesenchyme development The progression of the septum transversum from its initial formation to the mature structure. The septum transversum is a portion of the trunk mesenchyme. http://purl.obolibrary.org/obo/GO_0003344 pericardium morphogenesis http://purl.obolibrary.org/obo/GO_0048598 embryonic morphogenesis The process in which the anatomical structure of the pericardium is generated and organized. http://purl.obolibrary.org/obo/GO_0003348 cardiac endothelial cell differentiation http://purl.obolibrary.org/obo/GO_0045446 endothelial cell differentiation The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cardiac endothelial cell. http://purl.obolibrary.org/obo/CL_0000242 Merkel cell http://purl.obolibrary.org/obo/CL_0000710 neurecto-epithelial cell A specialized epithelial cell located in the skin epidermis and certain mucosal epithelia. It functions as a mechanoreceptor for light touch by forming synapse-like contacts with somatosensory afferent nerve endings, contributing to slowly adapting type I (SAI) tactile responses. Characterized by dense-core neuroendocrine granules, the Merkel cell exhibits both sensory and neuroendocrine properties, including regulated neurotransmitter release via SNARE complex-dependent mechanisms. Its development in mice depends on the transcription factor Atoh1. http://purl.obolibrary.org/obo/GO_0003352 regulation of cilium movement http://purl.obolibrary.org/obo/GO_0060632 regulation of microtubule-based movement Any process that modulates the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium. http://purl.obolibrary.org/obo/CL_0000244 transitional epithelial cell http://purl.obolibrary.org/obo/CL_0000066 epithelial cell A cell characteristically found lining hollow organs that are subject to great mechanical change due to contraction and distention; originally thought to represent a transition between stratified squamous and columnar epithelium. http://purl.obolibrary.org/obo/GO_0003353 positive regulation of cilium movement http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that increases the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium. http://purl.obolibrary.org/obo/CL_0000247 Rohon-Beard neuron http://purl.obolibrary.org/obo/CL_0000531 primary sensory neuron (sensu Teleostei) Type of neuron that is a primary mechanosensory cell, with peripheral neurites innervating the skin with free nerve endings. http://purl.obolibrary.org/obo/GO_0003354 negative regulation of cilium movement http://purl.obolibrary.org/obo/GO_0003352 regulation of cilium movement Any process that decreases the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium. http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell http://purl.obolibrary.org/obo/CL_0000000 cell Any cell that in taxon some Eukaryota. http://purl.obolibrary.org/obo/GO_0003357 noradrenergic neuron differentiation http://purl.obolibrary.org/obo/GO_0030182 neuron differentiation The process in which a relatively unspecialized cell acquires specialized features of an noradrenergic neuron, a neuron that secretes noradrenaline. http://purl.obolibrary.org/obo/CL_0000257 Eumycetozoan cell http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell Any cell that in taxon some Eumycetozoa. http://purl.obolibrary.org/obo/GO_0003358 noradrenergic neuron development http://purl.obolibrary.org/obo/GO_0048666 neuron development The process whose specific outcome is the progression of a noradrenergic neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. http://purl.obolibrary.org/obo/CL_0000286 hyphal cell http://purl.obolibrary.org/obo/CL_0000521 fungal cell A cell of a filament of a fungal mycelium. http://purl.obolibrary.org/obo/GO_0003360 brainstem development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the brainstem from its formation to the mature structure. The brainstem is the part of the brain that connects the brain with the spinal cord. http://purl.obolibrary.org/obo/CL_0000287 eye photoreceptor cell http://purl.obolibrary.org/obo/CL_0000210 photoreceptor cell Any photoreceptor cell that is part of some eye. http://purl.obolibrary.org/obo/GO_0003365 establishment of cell polarity involved in ameboidal cell migration http://purl.obolibrary.org/obo/GO_0030010 establishment of cell polarity The specification and formation of anisotropic intracellular organization that contributes to the self-propelled directed movement of an ameboid cell. http://purl.obolibrary.org/obo/CL_0000295 somatotropin secreting cell http://purl.obolibrary.org/obo/CL_0000167 peptide hormone secreting cell A peptide hormone secreting cell that produces growth hormone, somatotropin. http://purl.obolibrary.org/obo/GO_0003367 cell-cell adhesion involved in ameboidal cell migration http://purl.obolibrary.org/obo/GO_0098609 cell-cell adhesion The attachment of one ameboid cell to another that contributes to the establishment of cell polarity that is part of the directed movement of one of the cells. http://purl.obolibrary.org/obo/CL_0000300 gamete http://purl.obolibrary.org/obo/CL_0000586 germ cell A mature sexual reproductive cell having a single set of unpaired chromosomes. http://purl.obolibrary.org/obo/GO_0003371 establishment or maintenance of cytoskeleton polarity involved in ameboidal cell migration http://purl.obolibrary.org/obo/GO_0030952 establishment or maintenance of cytoskeleton polarity Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures that contribute to the cell polarity of a migrating ameboid cell. http://purl.obolibrary.org/obo/CL_0000301 pole cell http://purl.obolibrary.org/obo/CL_0000670 primordial germ cell A primordial germ cell of insects. Such cells form at the posterior pole of the early embryo. http://purl.obolibrary.org/obo/GO_0003379 establishment of cell polarity involved in gastrulation cell migration http://purl.obolibrary.org/obo/GO_0003365 establishment of cell polarity involved in ameboidal cell migration The specification and formation of anisotropic intracellular organization that contributes to the self-propelled directed movement of an ameboid cell taking part in gastrulation. http://purl.obolibrary.org/obo/CL_0000307 tracheal epithelial cell http://purl.obolibrary.org/obo/CL_0002202 epithelial cell of tracheobronchial tree An epithelial cell found in the trachea. http://purl.obolibrary.org/obo/GO_0003380 establishment or maintenance of cytoskeleton polarity involved in gastrulation http://purl.obolibrary.org/obo/GO_0003371 establishment or maintenance of cytoskeleton polarity involved in ameboidal cell migration Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures that contribute to the cell polarity of a migrating ameboid cell taking part in gastrulation. http://purl.obolibrary.org/obo/CL_0000312 keratinocyte http://purl.obolibrary.org/obo/CL_0000237 keratinizing barrier epithelial cell An epithelial cell of stratified squamous tissues, including skin, oral mucosa (Hiroshima et al., 2011), and esophagus (Whelan et al., 2018), that produces keratin proteins and secretes antimicrobial peptides to form a resilient barrier against environmental damage, dehydration, pathogens, and microbial invasion. It undergoes successive stages of differentiation marked by changes in keratin expression, supporting tissue integrity, wound repair, and contributing to immune defense. http://purl.obolibrary.org/obo/GO_0003381 epithelial cell morphogenesis involved in gastrulation http://purl.obolibrary.org/obo/GO_0003382 epithelial cell morphogenesis The change in form that occurs when an epithelial cell progresses from it initial formation to its mature state, contributing to the process of gastrulation. http://purl.obolibrary.org/obo/GO_0003382 epithelial cell morphogenesis http://purl.obolibrary.org/obo/GO_0000902 cell morphogenesis The change in form that occurs when an epithelial cell progresses from its initial formation to its mature state. http://purl.obolibrary.org/obo/CL_0000313 serous secreting cell http://purl.obolibrary.org/obo/CL_0000159 seromucus secreting cell Columnar glandular cell with irregular nucleus, copious granular endoplasmic reticulum and supranuclear granules. Secretes a watery fluid containing proteins known as serous fluid. http://purl.obolibrary.org/obo/GO_0003403 optic vesicle formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The developmental process pertaining to the initial formation of the optic vesicle from the lateral wall of the forebrain. This process begins with the specific processes that contribute to the appearance of the vesicle and ends when the vesicle has evaginated. The optic vesicle is the evagination of neurectoderm that precedes formation of the optic cup. http://purl.obolibrary.org/obo/CL_0000315 tear secreting cell http://purl.obolibrary.org/obo/CL_0000152 exocrine cell A cell secreting tears, the fluid secreted by the lacrimal glands. This fluid moistens the conjunctiva and cornea. http://purl.obolibrary.org/obo/GO_0003404 optic vesicle morphogenesis http://purl.obolibrary.org/obo/GO_0048729 tissue morphogenesis The developmental process pertaining to the formation and shaping of the optic vesicle. This process begins with the specific processes that contribute to the appearance of the vesicle and ends when the vesicle has evaginated. The optic vesicle is the evagination of neurectoderm that precedes formation of the optic cup. http://purl.obolibrary.org/obo/CL_0000317 sebocyte http://purl.obolibrary.org/obo/CL_2000021 sebaceous gland cell An epithelial cell that is part of a sebaceous gland. This cell produces and secretes sebum, an oily, lipid-rich substance, through holocrine secretion where the entire cell ruptures to release its contents. http://purl.obolibrary.org/obo/GO_0003406 retinal pigment epithelium development http://purl.obolibrary.org/obo/GO_0060429 epithelium development The progression of the retinal pigment epithelium over time, from its initial formation to the mature structure. The retinal pigment epithelium is the melanin-containing layer of cells between the retina and the choroid that absorbs scattered and reflected light and removes waste products produced by the photoreceptor cells. http://purl.obolibrary.org/obo/CL_0000318 sweat secreting cell http://purl.obolibrary.org/obo/CL_0000150 glandular secretory epithelial cell A cell secreting sweat, the fluid excreted by the sweat glands of mammals. It consists of water containing sodium chloride, phosphate, urea, ammonia, and other waste products. http://purl.obolibrary.org/obo/GO_0003407 neural retina development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells. http://purl.obolibrary.org/obo/CL_0000319 mucus secreting cell http://purl.obolibrary.org/obo/CL_0000159 seromucus secreting cell Any cell that is capable of some mucus secretion. http://purl.obolibrary.org/obo/GO_0003413 chondrocyte differentiation involved in endochondral bone morphogenesis http://purl.obolibrary.org/obo/GO_0002062 chondrocyte differentiation The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the development of a bone. A chondrocyte is a polymorphic cell that forms cartilage. http://purl.obolibrary.org/obo/GO_0003415 chondrocyte hypertrophy http://purl.obolibrary.org/obo/GO_0048588 developmental cell growth The growth of a chondrocyte, where growth contributes to the progression of the chondrocyte over time. http://purl.obolibrary.org/obo/CL_0000322 pulmonary alveolar epithelial cell http://purl.obolibrary.org/obo/CL_0000082 epithelial cell of lung An epithelial cell that lines the peripheral gas exchange region of the lungs of air-breathing vertebrates. http://purl.obolibrary.org/obo/GO_0003416 endochondral bone growth http://purl.obolibrary.org/obo/GO_0098868 bone growth The increase in size or mass of an endochondral bone that contributes to the shaping of the bone. http://purl.obolibrary.org/obo/CL_0000325 stuff accumulating cell http://purl.obolibrary.org/obo/CL_0000000 cell A cell that is specialised to accumulate a particular substance(s). http://purl.obolibrary.org/obo/GO_0003417 growth plate cartilage development http://purl.obolibrary.org/obo/GO_0061448 connective tissue development The process whose specific outcome is the progression of the cartilage that will provide a scaffold for mineralization of endochondral bones as they elongate or grow. http://purl.obolibrary.org/obo/CL_0000329 oxygen accumulating cell http://purl.obolibrary.org/obo/CL_0000000 cell Any cell that is capable of some oxygen transport. http://purl.obolibrary.org/obo/GO_0003418 growth plate cartilage chondrocyte differentiation http://purl.obolibrary.org/obo/GO_0003413 chondrocyte differentiation involved in endochondral bone morphogenesis The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the growth of a bone. A chondrocyte is a polymorphic cell that forms cartilage. http://purl.obolibrary.org/obo/CL_0000333 migratory neural crest cell http://purl.obolibrary.org/obo/CL_0011012 neural crest cell A cell derived from the specialized ectoderm flanking each side of the embryonic neural plate, which after the closure of the neural tube, forms masses of cells that migrate out from the dorsal aspect of the neural tube to spread throughout the body. http://purl.obolibrary.org/obo/GO_0003422 growth plate cartilage morphogenesis http://purl.obolibrary.org/obo/GO_0060536 cartilage morphogenesis The process in which the anatomical structures of growth plate cartilage are generated and organized. http://purl.obolibrary.org/obo/CL_0000335 mesenchyme condensation cell http://purl.obolibrary.org/obo/CL_0008019 mesenchymal cell A mesenchymal cell in embryonic development found in a contracting mass and that gives rise to osteoprogenitors. http://purl.obolibrary.org/obo/GO_0003429 growth plate cartilage chondrocyte morphogenesis http://purl.obolibrary.org/obo/GO_0090171 chondrocyte morphogenesis The process in which the structures of a chondrocyte in the growth plate cartilage are generated and organized. http://purl.obolibrary.org/obo/CL_0000336 adrenal medulla chromaffin cell http://purl.obolibrary.org/obo/CL_1000426 chromaffin cell of adrenal gland A cell found within the adrenal medulla that secrete biogenic amine hormones upon stimulation. http://purl.obolibrary.org/obo/GO_0003430 growth plate cartilage chondrocyte growth http://purl.obolibrary.org/obo/GO_0060560 developmental growth involved in morphogenesis The growth of a growth plate cartilage chondrocyte, where growth contributes to the progression of the chondrocyte over time from one condition to another. http://purl.obolibrary.org/obo/CL_0000338 neuroblast (sensu Nematoda and Protostomia) http://purl.obolibrary.org/obo/CL_0000047 neural stem cell A neural precursor of the central nervous system. http://purl.obolibrary.org/obo/GO_0003431 growth plate cartilage chondrocyte development http://purl.obolibrary.org/obo/GO_0003433 chondrocyte development involved in endochondral bone morphogenesis The progression of a growth plate cartilage chondrocyte over time from after its fate commitment to the mature cell. http://purl.obolibrary.org/obo/CL_0000339 glioblast (sensu Vertebrata) http://purl.obolibrary.org/obo/CL_0000123 neuron associated cell (sensu Vertebrata) An early neural cell developing from the early ependymal cell of the neural tube. http://purl.obolibrary.org/obo/GO_0003433 chondrocyte development involved in endochondral bone morphogenesis http://purl.obolibrary.org/obo/GO_0002063 chondrocyte development The progression of a chondrocyte over time from after its commitment to its mature state where the chondrocyte will contribute to the shaping of an endochondral bone. http://purl.obolibrary.org/obo/CL_0000340 glioblast (sensu Nematoda and Protostomia) http://purl.obolibrary.org/obo/CL_0000130 neuron associated cell (sensu Nematoda and Protostomia) A precursor of the central nervous system that gives rise to glial cells only. http://purl.obolibrary.org/obo/GO_0003676 nucleic acid binding http://purl.obolibrary.org/obo/GO_0005488 binding Binding to a nucleic acid. http://purl.obolibrary.org/obo/CL_0000342 pigment cell (sensu Vertebrata) http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell Any animal cell containing pigment granules. http://purl.obolibrary.org/obo/GO_0003677 DNA binding http://purl.obolibrary.org/obo/GO_0003676 nucleic acid binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). http://purl.obolibrary.org/obo/CL_0000343 visual pigment cell (sensu Vertebrata) http://purl.obolibrary.org/obo/CL_0000342 pigment cell (sensu Vertebrata) A pigment cell that is capable of detecting light stimulus that is involved in visual perception. http://purl.obolibrary.org/obo/GO_0003682 chromatin binding http://purl.obolibrary.org/obo/GO_0005488 binding Binding to chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase. http://purl.obolibrary.org/obo/CL_0000345 dental papilla cell http://purl.obolibrary.org/obo/CL_0008019 mesenchymal cell A mesenchymal cell that is part of a small mass of condensed mesenchyme in the enamel organ; it differentiates into the dentin and dental pulp. http://purl.obolibrary.org/obo/GO_0003723 RNA binding http://purl.obolibrary.org/obo/GO_0003676 nucleic acid binding Binding to an RNA molecule or a portion thereof. http://purl.obolibrary.org/obo/CL_0000346 hair follicle dermal papilla cell http://purl.obolibrary.org/obo/CL_1000302 fibroblast of papillary layer of dermis A specialized fibroblast that resides in the dermal papilla located at the bottom of hair follicles. This cell orchestrates reciprocal epithelial-mesenchymal signaling essential for hair follicle morphogenesis and cycling, regulating matrix cell proliferation and differentiation to control hair shaft size, shape, and growth. The dermal papilla cell is replenished each hair cycle from bipotent hair follicle dermal stem cells in the dermal sheath that simultaneously self-renew and contribute progeny to the papilla, particularly during anagen. http://purl.obolibrary.org/obo/GO_0003774 cytoskeletal motor activity http://purl.obolibrary.org/obo/GO_0003674 molecular_function Generation of force resulting in movement, for example along a microfilament or microtubule, or in torque resulting in membrane scission or rotation of a flagellum. The energy required is obtained either from the hydrolysis of a nucleoside triphosphate or by an electrochemical proton gradient (proton-motive force). http://purl.obolibrary.org/obo/CL_0000347 scleral cell http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell A cell of the sclera of the eye. http://purl.obolibrary.org/obo/GO_0003777 microtubule motor activity http://purl.obolibrary.org/obo/GO_0140657 ATP-dependent activity A motor activity that generates movement along a microtubule, driven by ATP hydrolysis. http://purl.obolibrary.org/obo/CL_0000348 choroidal cell of the eye http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell A cell that is part of optic choroid. http://purl.obolibrary.org/obo/GO_0003824 catalytic activity http://purl.obolibrary.org/obo/GO_0003674 molecular_function Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic. http://purl.obolibrary.org/obo/CL_0000349 extraembryonic cell http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell Any cell that is part of some extraembryonic structure. http://purl.obolibrary.org/obo/GO_0004888 transmembrane signaling receptor activity http://purl.obolibrary.org/obo/GO_0038023 signaling receptor activity Combining with an extracellular or intracellular signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity or state as part of signal transduction. http://purl.obolibrary.org/obo/CL_0000350 amnioserosal cell http://purl.obolibrary.org/obo/CL_0000349 extraembryonic cell Any extraembryonic cell that is part of some amnioserosa. http://purl.obolibrary.org/obo/GO_0004896 cytokine receptor activity http://purl.obolibrary.org/obo/GO_0140375 immune receptor activity Combining with a cytokine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. http://purl.obolibrary.org/obo/CL_0000351 trophoblast cell http://purl.obolibrary.org/obo/CL_0000349 extraembryonic cell An extraembryonic cell that develops from a trophectodermal cell. This cell is found in the outer layer of the blastocyst and can invade other structures in the uterus once the blastocyst implants into the uterine wall. A trophoblast cell is involved in the implantation of the embryo into the uterine wall, placental formation, remodelling of maternal vasculature in the uterus, nutrient and gas exchange, hormone production, and immune modulation to support fetal development. http://purl.obolibrary.org/obo/GO_0004930 G protein-coupled receptor activity http://purl.obolibrary.org/obo/GO_0004888 transmembrane signaling receptor activity Combining with an extracellular signal and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. http://purl.obolibrary.org/obo/CL_0000352 epiblast cell http://purl.obolibrary.org/obo/CL_0000052 totipotent stem cell A cell of the outer layer of a blastula that gives rise to the ectoderm after gastrulation. http://purl.obolibrary.org/obo/GO_0004983 neuropeptide Y receptor activity http://purl.obolibrary.org/obo/GO_0008188 neuropeptide receptor activity Combining with neuropeptide Y to initiate a change in cell activity. http://purl.obolibrary.org/obo/CL_0000353 blastoderm cell http://purl.obolibrary.org/obo/CL_0000007 early embryonic cell (metazoa) An undifferentiated cell produced by early cleavages of the fertilized egg (zygote). http://purl.obolibrary.org/obo/GO_0004993 G protein-coupled serotonin receptor activity http://purl.obolibrary.org/obo/GO_0008227 G protein-coupled amine receptor activity Combining with the biogenic amine serotonin and transmitting the signal across the membrane by activating an associated G-protein. Serotonin (5-hydroxytryptamine) is a neurotransmitter and hormone found in vertebrates and invertebrates. http://purl.obolibrary.org/obo/CL_0000355 multi-potent skeletal muscle stem cell http://purl.obolibrary.org/obo/CL_0000188 cell of skeletal muscle A multifate stem cell found in skeletal muscle than can differentiate into many different cell types, including muscle. Distinct cell type from satellite cell. http://purl.obolibrary.org/obo/GO_0005102 signaling receptor binding http://purl.obolibrary.org/obo/GO_0005515 protein binding Binding to one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function. http://purl.obolibrary.org/obo/CL_0000358 sphincter associated smooth muscle cell http://purl.obolibrary.org/obo/CL_0000192 smooth muscle cell A smooth muscle cell that is part of a sphincter. A sphincter is a typically circular muscle that normally maintains constriction of a natural body passage or orifice and which relaxes as required by normal physiological functioning. http://purl.obolibrary.org/obo/GO_0005126 cytokine receptor binding http://purl.obolibrary.org/obo/GO_0005102 signaling receptor binding Binding to a cytokine receptor. http://purl.obolibrary.org/obo/CL_0000359 vascular associated smooth muscle cell http://purl.obolibrary.org/obo/CL_4033054 perivascular cell A smooth muscle cell associated with the vasculature. http://purl.obolibrary.org/obo/GO_0005488 binding http://purl.obolibrary.org/obo/GO_0003674 molecular_function The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule. http://purl.obolibrary.org/obo/CL_0000360 morula cell http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell A cell of the early embryo at the developmental stage in which the blastomeres, resulting from repeated mitotic divisions of the fertilized ovum (zygote), form a compact cell mass. http://purl.obolibrary.org/obo/GO_0005515 protein binding http://purl.obolibrary.org/obo/GO_0005488 binding Binding to a protein. http://purl.obolibrary.org/obo/GO_0005622 intracellular anatomical structure http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure A component of a cell contained within (but not including) the plasma membrane. In eukaryotes it includes the nucleus and cytoplasm. http://purl.obolibrary.org/obo/CL_0000361 gastrula cell http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell A cell of the embryo in the early stage following the blastula, characterized by morphogenetic cell movements, cell differentiation, and the formation of the three germ layers. http://purl.obolibrary.org/obo/GO_0005634 nucleus http://purl.obolibrary.org/obo/GO_0043231 intracellular membrane-bounded organelle A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. http://purl.obolibrary.org/obo/CL_0000362 epidermal cell http://purl.obolibrary.org/obo/CL_0002159 general ecto-epithelial cell An epithelial cell of the integument (the outer layer of an organism). http://purl.obolibrary.org/obo/GO_0005694 chromosome http://purl.obolibrary.org/obo/GO_0043232 intracellular membraneless organelle A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information. http://purl.obolibrary.org/obo/CL_0000365 animal zygote http://purl.obolibrary.org/obo/CL_0010017 zygote Diploid cell produced by the fusion of sperm cell nucleus and egg cell. http://purl.obolibrary.org/obo/GO_0005737 cytoplasm http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. http://purl.obolibrary.org/obo/CL_0000371 protoplast http://purl.obolibrary.org/obo/CL_0000578 experimentally modified cell in vitro The cell protoplasm after removal of the cell wall. http://purl.obolibrary.org/obo/GO_0005739 mitochondrion http://purl.obolibrary.org/obo/GO_0043231 intracellular membrane-bounded organelle A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. http://purl.obolibrary.org/obo/CL_0000372 tormogen cell http://purl.obolibrary.org/obo/CL_0000463 epidermal cell (sensu Arthropoda) An epidermal cell that is part of a cell cluster organ of the insect integument (such as a sensillum) and that secretes a cuticular specialization that forms a socket around the base of a cuticular specialization produced by a trichogen cell. http://purl.obolibrary.org/obo/GO_0005741 mitochondrial outer membrane http://purl.obolibrary.org/obo/GO_0031968 organelle outer membrane The outer, i.e. cytoplasm-facing, lipid bilayer of the mitochondrial envelope. http://purl.obolibrary.org/obo/CL_0000373 histoblast http://purl.obolibrary.org/obo/CL_0011026 progenitor cell A progenitor cell found in the larval epidermis of insects and that gives rise to the adult abdominal epidermis. http://purl.obolibrary.org/obo/GO_0005764 lysosome http://purl.obolibrary.org/obo/GO_0000323 lytic vacuole A small lytic vacuole that has cell cycle-independent morphology found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions. http://purl.obolibrary.org/obo/CL_0000374 trichogen cell http://purl.obolibrary.org/obo/CL_0000463 epidermal cell (sensu Arthropoda) An epidermal cell that is part of a cell cluster organ of the insect integument (such as a sensillum) and that secretes a cuticular specialization, often in the form of a hair, bristle, peg or scale. The base of this specialization is often surrounded by a socket produced by a closely associated tormogen cell. http://purl.obolibrary.org/obo/GO_0005773 vacuole http://purl.obolibrary.org/obo/GO_0043231 intracellular membrane-bounded organelle A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol. http://purl.obolibrary.org/obo/CL_0000380 thecogen cell http://purl.obolibrary.org/obo/CL_0000378 supporting cell (sensu Nematoda and Protostomia) The support cell that makes the thecogen dendritic cap - a cuticle-like matrix around the tip of the eo-dendrite and which encloses the soma of the eo-neuron. http://purl.obolibrary.org/obo/GO_0005774 vacuolar membrane http://purl.obolibrary.org/obo/GO_0098588 bounding membrane of organelle The lipid bilayer surrounding the vacuole and separating its contents from the cytoplasm of the cell. http://purl.obolibrary.org/obo/CL_0000382 scolopale cell http://purl.obolibrary.org/obo/CL_0000378 supporting cell (sensu Nematoda and Protostomia) A cell that is part of a scolopidium and surrounds the dendrite of a scolopidial neuron. http://purl.obolibrary.org/obo/GO_0005775 vacuolar lumen http://purl.obolibrary.org/obo/GO_0070013 intracellular organelle lumen The volume enclosed within the vacuolar membrane. http://purl.obolibrary.org/obo/CL_0000385 prohemocyte (sensu Nematoda and Protostomia) http://purl.obolibrary.org/obo/CL_0008001 hematopoietic precursor cell A precursor of mature hemocytes. http://purl.obolibrary.org/obo/GO_0005815 microtubule organizing center http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure An intracellular structure that can catalyze gamma-tubulin-dependent microtubule nucleation and that can anchor microtubules by interacting with their minus ends, plus ends or sides. http://purl.obolibrary.org/obo/CL_0000387 hemocyte (sensu Arthropoda) http://purl.obolibrary.org/obo/CL_0000390 blood cell (sensu Nematoda and Protostomia) A blood cell of the circulatory system of arthropods. http://purl.obolibrary.org/obo/CL_0000392 crystal cell http://purl.obolibrary.org/obo/CL_0000387 hemocyte (sensu Arthropoda) A hemocyte that synthesizes and secretes melanins as part of the antimicrobial immune response. It is characterized morphologically by crystal inclusions of phenoloxidases in its cytoplasm, hence its name. http://purl.obolibrary.org/obo/GO_0005829 cytosol http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. http://purl.obolibrary.org/obo/CL_0000393 electrically responsive cell http://purl.obolibrary.org/obo/CL_0000211 electrically active cell A cell whose function is determined by its response to an electric signal. http://purl.obolibrary.org/obo/GO_0005840 ribosome http://purl.obolibrary.org/obo/GO_0043232 intracellular membraneless organelle An intracellular organelle, about 200 A in diameter, consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA). It consists of two subunits, one large and one small, each containing only protein and RNA. Both the ribosome and its subunits are characterized by their sedimentation coefficients, expressed in Svedberg units (symbol: S). Hence, the prokaryotic ribosome (70S) comprises a large (50S) subunit and a small (30S) subunit, while the eukaryotic ribosome (80S) comprises a large (60S) subunit and a small (40S) subunit. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site). Ribosomes from prokaryotes, eukaryotes, mitochondria, and chloroplasts have characteristically distinct ribosomal proteins. http://purl.obolibrary.org/obo/CL_0000394 plasmatocyte http://purl.obolibrary.org/obo/CL_0000387 hemocyte (sensu Arthropoda) A phagocytic hemocyte, responsible for the engulfment of small particles, microbes, and apoptotic tissue debris. It may also secretes antimicrobial peptides and contribute to the production and secretion of proteins of the hemolymph. http://purl.obolibrary.org/obo/GO_0005881 cytoplasmic microtubule http://purl.obolibrary.org/obo/GO_0005874 microtubule Any microtubule in the cytoplasm of a cell. http://purl.obolibrary.org/obo/CL_0000395 procrystal cell http://purl.obolibrary.org/obo/CL_0000385 prohemocyte (sensu Nematoda and Protostomia) A precursor of mature crystal cells. http://purl.obolibrary.org/obo/GO_0005886 plasma membrane http://purl.obolibrary.org/obo/GO_0016020 membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. http://purl.obolibrary.org/obo/CL_0000396 lamellocyte http://purl.obolibrary.org/obo/CL_0000387 hemocyte (sensu Arthropoda) A hemocyte found in immuno-stimulated larvae. http://purl.obolibrary.org/obo/GO_0005976 polysaccharide metabolic process http://purl.obolibrary.org/obo/GO_0043170 macromolecule metabolic process The chemical reactions and pathways involving a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically. http://purl.obolibrary.org/obo/CL_0000397 ganglion interneuron http://purl.obolibrary.org/obo/CL_0000099 interneuron Any interneuron that has its soma located in some ganglion. http://purl.obolibrary.org/obo/CL_0000404 electrically signaling cell http://purl.obolibrary.org/obo/CL_0000211 electrically active cell A cell that initiates an electrical signal and passes that signal to another cell. http://purl.obolibrary.org/obo/GO_0005977 glycogen metabolic process http://purl.obolibrary.org/obo/GO_0044042 glucan metabolic process The chemical reactions and pathways involving glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues in alpha-(1->4) glycosidic linkage, joined together by alpha-(1->6) glycosidic linkages. http://purl.obolibrary.org/obo/CL_0000407 scolopidial ligament cell http://purl.obolibrary.org/obo/CL_0000378 supporting cell (sensu Nematoda and Protostomia) A cell that anchors the cell body of a scolopidial neuron to the integument. http://purl.obolibrary.org/obo/GO_0006259 DNA metabolic process http://purl.obolibrary.org/obo/GO_0090304 nucleic acid metabolic process Any cellular metabolic process involving deoxyribonucleic acid. This is one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides. http://purl.obolibrary.org/obo/CL_0000408 male gamete http://purl.obolibrary.org/obo/CL_0000300 gamete Any male germ cell that has characteristic some haploid and is capable of some fertilization. http://purl.obolibrary.org/obo/GO_0006308 DNA catabolic process http://purl.obolibrary.org/obo/GO_0141188 nucleic acid catabolic process The cellular DNA metabolic process resulting in the breakdown of DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long unbranched macromolecule formed from one or two strands of linked deoxyribonucleotides, the 3'-phosphate group of each constituent deoxyribonucleotide being joined in 3',5'-phosphodiester linkage to the 5'-hydroxyl group of the deoxyribose moiety of the next one. http://purl.obolibrary.org/obo/CL_0000411 Caenorhabditis hypodermal cell http://purl.obolibrary.org/obo/CL_0000228 multinucleate cell An epithelial cell of the hypodermis of Caenorhabditis. http://purl.obolibrary.org/obo/GO_0006310 DNA recombination http://purl.obolibrary.org/obo/GO_0006259 DNA metabolic process Any process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Interchromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction. http://purl.obolibrary.org/obo/CL_0000412 polyploid cell http://purl.obolibrary.org/obo/CL_0000000 cell A cell that contains more than two haploid sets of chromosomes. http://purl.obolibrary.org/obo/GO_0006325 chromatin organization http://purl.obolibrary.org/obo/GO_0016043 cellular component organization The assembly or remodeling of chromatin composed of DNA complexed with histones, other associated proteins, and sometimes RNA. http://purl.obolibrary.org/obo/CL_0000413 haploid cell http://purl.obolibrary.org/obo/CL_0000000 cell A cell whose nucleus contains a single haploid genome. http://purl.obolibrary.org/obo/CL_0000415 diploid cell http://purl.obolibrary.org/obo/CL_0000000 cell A cell whose nucleus has two haploid genomes. http://purl.obolibrary.org/obo/GO_0006401 RNA catabolic process http://purl.obolibrary.org/obo/GO_0141188 nucleic acid catabolic process The chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. http://purl.obolibrary.org/obo/CL_0000418 arcade cell http://purl.obolibrary.org/obo/CL_0000066 epithelial cell An epithelial cell found in C. elegans that firmly hold the outer body wall and the lips to the inner cylinder of the pharynx in a manner that keeps these organs from breaking apart, while still giving each organ freedom of movement during feeding. http://purl.obolibrary.org/obo/GO_0006412 translation http://purl.obolibrary.org/obo/GO_0009059 macromolecule biosynthetic process The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome. http://purl.obolibrary.org/obo/CL_0000419 seam cell http://purl.obolibrary.org/obo/CL_0000036 epithelial fate stem cell An epithelial fate stem cell found in flatworms. http://purl.obolibrary.org/obo/GO_0006413 translational initiation http://purl.obolibrary.org/obo/GO_0008152 metabolic process The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA. http://purl.obolibrary.org/obo/CL_0000420 syncytial epithelial cell http://purl.obolibrary.org/obo/CL_0000066 epithelial cell An epithelial cell that forms a syncytium, which is a multinucleated cell resulting from the fusion of multiple cells. http://purl.obolibrary.org/obo/GO_0006414 translational elongation http://purl.obolibrary.org/obo/GO_0009059 macromolecule biosynthetic process The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis. http://purl.obolibrary.org/obo/CL_0000421 coelomocyte http://purl.obolibrary.org/obo/CL_0000519 phagocyte (sensu Nematoda and Protostomia) A free floating cell, including amebocytes and eleocytes, in the coelom of certain animals, especially annelids. http://purl.obolibrary.org/obo/GO_0006415 translational termination http://purl.obolibrary.org/obo/GO_0032984 protein-containing complex disassembly The process resulting in the release of a polypeptide chain from the ribosome, usually in response to a termination codon (UAA, UAG, or UGA in the universal genetic code). http://purl.obolibrary.org/obo/CL_0000422 mitogenic signaling cell http://purl.obolibrary.org/obo/CL_0000000 cell A cell whose primary function is to cause growth by stimulating cell division in its immediate cellular environment. http://purl.obolibrary.org/obo/GO_0006508 proteolysis http://purl.obolibrary.org/obo/GO_0019538 protein metabolic process The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds. http://purl.obolibrary.org/obo/CL_0000424 excretory cell http://purl.obolibrary.org/obo/CL_0000000 cell A cell involved in the elimination of metabolic and foreign toxins, and in maintaining the ionic, acid-base and water balance of biological fluids. http://purl.obolibrary.org/obo/GO_0006520 amino acid metabolic process http://purl.obolibrary.org/obo/GO_0044238 primary metabolic process The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups. http://purl.obolibrary.org/obo/CL_0000425 pore cell http://purl.obolibrary.org/obo/CL_0000658 cuticle secreting cell Forms the terminal part of the cuticle-lined excretory duct of C. elegans. http://purl.obolibrary.org/obo/GO_0006521 regulation of amino acid metabolic process http://purl.obolibrary.org/obo/GO_0080090 regulation of primary metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amino acids. http://purl.obolibrary.org/obo/CL_0000427 GLR cell http://purl.obolibrary.org/obo/CL_0002320 connective tissue cell A scaffolding cell type found in C. elegans, this cell plays a supportive role to the muscle arms. May also have an endocrine role. http://purl.obolibrary.org/obo/GO_0006547 L-histidine metabolic process http://purl.obolibrary.org/obo/GO_0170033 L-amino acid metabolic process The chemical reactions and pathways involving L-histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid. http://purl.obolibrary.org/obo/CL_0000429 imaginal disc cell http://purl.obolibrary.org/obo/CL_0000146 simple columnar epithelial cell A columnar epithelial cell that is part of an insect imaginal disc. http://purl.obolibrary.org/obo/GO_0006575 modified amino acid metabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process The chemical reactions and pathways involving compounds derived from amino acids, organic acids containing one or more amino substituents. http://purl.obolibrary.org/obo/CL_0000430 xanthophore cell http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell A pigment cell derived from the neural crest. Contains cartenoid pigments in structures called pterinosomes or xanthosomes. This gives an appearance ranging from a golden yellow to orange and red. http://purl.obolibrary.org/obo/GO_0006576 biogenic amine metabolic process http://purl.obolibrary.org/obo/GO_0009308 amine metabolic process The chemical reactions and pathways occurring at the level of individual cells involving any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters. http://purl.obolibrary.org/obo/CL_0000431 iridophore http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell A pigment cell derived from the neural crest. The cell contains flat light-reflecting platelets, probably of guanine, in stacks called reflecting platelets or iridisomes. The color-generating components produce a silver, gold, or iridescent color. http://purl.obolibrary.org/obo/GO_0006581 acetylcholine catabolic process http://purl.obolibrary.org/obo/GO_0009056 catabolic process The chemical reactions and pathways resulting in the breakdown of acetylcholine, the acetic acid ester of the organic base choline. http://purl.obolibrary.org/obo/CL_0000432 reticular cell http://purl.obolibrary.org/obo/CL_0000057 fibroblast A fibroblast that synthesizes collagen and uses it to produce reticular fibers, thus providing structural support. Reticular cells are found in many organs, including the spleen, lymph nodes and kidneys. Subtypes of reticular cells include epithelial, mesenchymal, and fibroblastic reticular cells. Fibroblastic reticular cells are involved in directing B cells and T cells to specific regions within a tissue, whereas epithelial and mesenchymal reticular cells are associated with certain areas of the brain. http://purl.obolibrary.org/obo/GO_0006606 protein import into nucleus http://purl.obolibrary.org/obo/GO_0006886 intracellular protein transport The directed movement of a protein from the cytoplasm to the nucleus. http://purl.obolibrary.org/obo/CL_0000434 eccrine cell http://purl.obolibrary.org/obo/CL_1100001 secretory epithelial cell A secretory cell that discharges its product without loss of cytoplasm. http://purl.obolibrary.org/obo/GO_0006631 fatty acid metabolic process http://purl.obolibrary.org/obo/GO_0032787 monocarboxylic acid metabolic process The chemical reactions and pathways involving fatty acids, aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis. http://purl.obolibrary.org/obo/CL_0000437 gonadtroph http://purl.obolibrary.org/obo/CL_0000639 basophil cell of pars distalis of adenohypophysis A rounded cell that is usually situated next to sinusoids; secretes follicular stimulating hormone (FSH) and luteinizing hormone (LH). http://purl.obolibrary.org/obo/GO_0006633 fatty acid biosynthetic process http://purl.obolibrary.org/obo/GO_0072330 monocarboxylic acid biosynthetic process The chemical reactions and pathways resulting in the formation of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes. http://purl.obolibrary.org/obo/CL_0000438 luteinizing hormone secreting cell http://purl.obolibrary.org/obo/CL_0000151 secretory cell A peptide hormone secreting cell pituitary that produces luteinizing hormone. http://purl.obolibrary.org/obo/GO_0006687 glycosphingolipid metabolic process http://purl.obolibrary.org/obo/GO_0006665 sphingolipid metabolic process The chemical reactions and pathways involving glycosphingolipids, any compound with residues of sphingoid and at least one monosaccharide. http://purl.obolibrary.org/obo/CL_0000439 prolactin secreting cell http://purl.obolibrary.org/obo/CL_0000167 peptide hormone secreting cell A peptide hormone cell that secretes prolactin. http://purl.obolibrary.org/obo/GO_0006688 glycosphingolipid biosynthetic process http://purl.obolibrary.org/obo/GO_0006687 glycosphingolipid metabolic process The chemical reactions and pathways resulting in the formation of a glycosphingolipid, a compound composed of a ceramide backbone covalently linked to at least one carbohydrate moiety. http://purl.obolibrary.org/obo/CL_0000440 melanocyte stimulating hormone secreting cell http://purl.obolibrary.org/obo/CL_0000167 peptide hormone secreting cell A cell of the intermediate pituitary that produces melanocyte stimulating hormone. http://purl.obolibrary.org/obo/GO_0006790 sulfur compound metabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process The chemical reactions and pathways involving the nonmetallic element sulfur or compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione. http://purl.obolibrary.org/obo/CL_0000441 follicle stem cell (sensu Arthropoda) http://purl.obolibrary.org/obo/CL_0000036 epithelial fate stem cell A stem cell that gives rise to the follicle cells that surround the oocyte in female arthropods. http://purl.obolibrary.org/obo/GO_0006814 sodium ion transport http://purl.obolibrary.org/obo/GO_0030001 metal ion transport The directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/CL_0000442 follicular dendritic cell http://purl.obolibrary.org/obo/CL_0000451 dendritic cell A cell with extensive dendritic processes found in the B cell areas (primary follicles and germinal centers) of lymphoid tissue. They are unrelated to the dendritic cell associated with T cells. Follicular dendritic cells have Fc receptors and C3b receptors, but unlike other dendritic cells, they do not process or present antigen in a way that allows recognition by T cells. Instead, they hold antigen in the form of immune complexes on their surfaces for long periods and can present antigen to B cells during an immune response. http://purl.obolibrary.org/obo/GO_0006816 calcium ion transport http://purl.obolibrary.org/obo/GO_0030001 metal ion transport The directed movement of calcium (Ca) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/CL_0000443 calcitonin secreting cell http://purl.obolibrary.org/obo/CL_0000167 peptide hormone secreting cell Any secretory cell that is capable of some calcitonin secretion. http://purl.obolibrary.org/obo/GO_0006833 water transport http://purl.obolibrary.org/obo/GO_0042044 fluid transport The directed movement of water (H2O) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/CL_0000444 obliquely striated muscle cell http://purl.obolibrary.org/obo/CL_0000737 striated muscle cell A muscle cell in which the fibers are organised into sarcomeres but in which adjacent myofibrils are offset from each other, producing an oblique banding pattern. http://purl.obolibrary.org/obo/GO_0006836 neurotransmitter transport http://purl.obolibrary.org/obo/GO_0006810 transport The directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Neurotransmitters are any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell. http://purl.obolibrary.org/obo/CL_0000446 chief cell of parathyroid gland http://purl.obolibrary.org/obo/CL_1001593 parathyroid glandular cell An epithelial cell of the parathyroid gland that is arranged in wide, irregular interconnecting columns; responsible for the synthesis and secretion of parathyroid hormone. http://purl.obolibrary.org/obo/GO_0006837 serotonin transport http://purl.obolibrary.org/obo/GO_0015850 organic hydroxy compound transport The directed movement of serotonin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Serotonin (5-hydroxytryptamine) is a monoamine neurotransmitter occurring in the peripheral and central nervous systems. http://purl.obolibrary.org/obo/CL_0000448 white adipocyte http://purl.obolibrary.org/obo/CL_0000136 adipocyte An adipocyte with light coloration and few mitochondria. It contains a scant ring of cytoplasm surrounding a single large lipid droplet or vacuole. http://purl.obolibrary.org/obo/GO_0006839 mitochondrial transport http://purl.obolibrary.org/obo/GO_0046907 intracellular transport Transport of substances into, out of or within a mitochondrion. http://purl.obolibrary.org/obo/CL_0000449 brown adipocyte http://purl.obolibrary.org/obo/CL_0000136 adipocyte A cell from the thermogenic form of adipose tissue found in many species, particularly in newborns and hibernating mammals, but also in lesser amounts in adults of other mammals including humans. Brown fat is capable of rapid liberation of energy and seems to be important in the maintenance of body temperature immediately after birth and upon waking from hibernation. http://purl.obolibrary.org/obo/GO_0006865 amino acid transport http://purl.obolibrary.org/obo/GO_0006810 transport The directed movement of amino acids, organic acids containing one or more amino substituents, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/CL_0000451 dendritic cell http://purl.obolibrary.org/obo/CL_0000145 professional antigen presenting cell A cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation. These cells are lineage negative (CD3-negative, CD19-negative, CD34-negative, and CD56-negative). http://purl.obolibrary.org/obo/GO_0006869 lipid transport http://purl.obolibrary.org/obo/GO_0006810 transport The directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Lipids are compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. http://purl.obolibrary.org/obo/CL_0000453 Langerhans cell http://purl.obolibrary.org/obo/CL_0000990 conventional dendritic cell Langerhans cell is a conventional dendritic cell that has plasma membrane part CD207. A Langerhans cell is a stellate dendritic cell of myeloid origin, that appears clear on light microscopy and has a dark-staining, indented nucleus and characteristic inclusions (Birbeck granules) in the cytoplasm; Langerhans cells are found principally in the stratum spinosum of the epidermis, but they also occur in other stratified epithelia and have been identified in the lung, lymph nodes, spleen, and thymus. http://purl.obolibrary.org/obo/GO_0006886 intracellular protein transport http://purl.obolibrary.org/obo/GO_0046907 intracellular transport The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell. http://purl.obolibrary.org/obo/CL_0000454 epinephrine secreting cell http://purl.obolibrary.org/obo/CL_0000457 biogenic amine secreting cell A cell capable of producing epinephrine. Epiniphrine is synthesized from norepiniphrine by the actions of the phenylethanolamine N-methyltransferase enzyme, which is expressed in the adrenal glands, androgenic neurons, and in other cell types. http://purl.obolibrary.org/obo/GO_0006909 phagocytosis http://purl.obolibrary.org/obo/GO_0006897 endocytosis A vesicle-mediated transport process that results in the engulfment of external particulate material by phagocytes and their delivery to the lysosome. The particles are initially contained within phagocytic vacuoles (phagosomes), which then fuse with primary lysosomes to effect digestion of the particles. http://purl.obolibrary.org/obo/CL_0000456 mineralocorticoid secreting cell http://purl.obolibrary.org/obo/CL_0000174 steroid hormone secreting cell Any secretory cell that is capable of some mineralocorticoid secretion. http://purl.obolibrary.org/obo/GO_0006913 nucleocytoplasmic transport http://purl.obolibrary.org/obo/GO_0051169 nuclear transport The directed movement of molecules between the nucleus and the cytoplasm. http://purl.obolibrary.org/obo/CL_0000458 serotonin secreting cell http://purl.obolibrary.org/obo/CL_0000457 biogenic amine secreting cell A cell type that secretes 5-Hydroxytryptamine (serotonin). http://purl.obolibrary.org/obo/GO_0006915 apoptotic process http://purl.obolibrary.org/obo/GO_0012501 programmed cell death A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died. http://purl.obolibrary.org/obo/CL_0000459 noradrenergic cell http://purl.obolibrary.org/obo/CL_0000457 biogenic amine secreting cell A cell capable of producting norepiniphrine. Norepiniphrine is a catecholamine with multiple roles including as a hormone and a neurotransmitter. In addition, epiniphrine is synthesized from norepiniphrine by the actions of the phenylethanolamine N-methyltransferase enzyme. http://purl.obolibrary.org/obo/GO_0006925 inflammatory cell apoptotic process http://purl.obolibrary.org/obo/GO_0006915 apoptotic process Any apoptotic process in an inflammatory cell, any cell participating in the inflammatory response to a foreign substance e.g. neutrophil, macrophage. http://purl.obolibrary.org/obo/CL_0000460 glucocorticoid secreting cell http://purl.obolibrary.org/obo/CL_0000174 steroid hormone secreting cell Any secretory cell that is capable of some glucocorticoid secretion. http://purl.obolibrary.org/obo/GO_0006940 regulation of smooth muscle contraction http://purl.obolibrary.org/obo/GO_0006937 regulation of muscle contraction Any process that modulates the frequency, rate or extent of smooth muscle contraction. http://purl.obolibrary.org/obo/CL_0000462 adepithelial cell http://purl.obolibrary.org/obo/CL_0000680 muscle precursor cell A cell of mesodermal origin that is closely associated with the epithelium of an imaginal disc. It is a precursor of some of the insect's adult muscles. http://purl.obolibrary.org/obo/GO_0006941 striated muscle contraction http://purl.obolibrary.org/obo/GO_0006936 muscle contraction A process in which force is generated within striated muscle tissue, resulting in the shortening of the muscle. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Striated muscle is a type of muscle in which the repeating units (sarcomeres) of the contractile myofibrils are arranged in registry throughout the cell, resulting in transverse or oblique striations observable at the level of the light microscope. http://purl.obolibrary.org/obo/CL_0000463 epidermal cell (sensu Arthropoda) http://purl.obolibrary.org/obo/CL_0000710 neurecto-epithelial cell An epidermal cell that secretes chitinous cuticle from its apical side. http://purl.obolibrary.org/obo/GO_0006949 syncytium formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane. Syncytia are normally derived from single cells that fuse or fail to complete cell division. http://purl.obolibrary.org/obo/CL_0000464 epidermoblast http://purl.obolibrary.org/obo/CL_0011026 progenitor cell An epidermal progenitor cell that arises from neuroectoderm and in turn gives rise to the epidermal sheath of ventral and cephalic regions. http://purl.obolibrary.org/obo/GO_0006950 response to stress http://purl.obolibrary.org/obo/GO_0050896 response to stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). http://purl.obolibrary.org/obo/CL_0000465 cardioblast (sensu Arthropoda) http://purl.obolibrary.org/obo/CL_0010021 cardiac myoblast A precursor of the cells that form the dorsal vessel of arthropods. http://purl.obolibrary.org/obo/GO_0006952 defense response http://purl.obolibrary.org/obo/GO_0006950 response to stress Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack. http://purl.obolibrary.org/obo/CL_0000467 adrenocorticotropic hormone secreting cell http://purl.obolibrary.org/obo/CL_0000167 peptide hormone secreting cell A peptide hormone secreting cell that produces adrenocorticotropin, or corticotropin. http://purl.obolibrary.org/obo/GO_0006954 inflammatory response http://purl.obolibrary.org/obo/GO_0006952 defense response The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages. http://purl.obolibrary.org/obo/CL_0000468 neuroglioblast (sensu Nematoda and Protostomia) http://purl.obolibrary.org/obo/CL_0000047 neural stem cell A precursor of the central nervous system that gives rise to both neurons and glial cells. http://purl.obolibrary.org/obo/GO_0006955 immune response http://purl.obolibrary.org/obo/GO_0002376 immune system process Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. http://purl.obolibrary.org/obo/CL_0000469 ganglion mother cell http://purl.obolibrary.org/obo/CL_0011020 neural progenitor cell A neural progenitor cell that is the daughter of a neuroblast (sensu arthopoda). The progeny of ganglion mother cells develop into neurons, glia and (occasionally) epithelial cells. http://purl.obolibrary.org/obo/GO_0006959 humoral immune response http://purl.obolibrary.org/obo/GO_0006955 immune response An immune response mediated through a body fluid. http://purl.obolibrary.org/obo/CL_0000474 pericardial nephrocyte http://purl.obolibrary.org/obo/CL_0002520 nephrocyte An insect renal cell that filters hemolymph and is found with other pericardial nephrocytes in two rows flanking the dorsal vessel. http://purl.obolibrary.org/obo/GO_0006979 response to oxidative stress http://purl.obolibrary.org/obo/GO_0006950 response to stress Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals. http://purl.obolibrary.org/obo/CL_0000476 thyrotroph http://purl.obolibrary.org/obo/CL_0000639 basophil cell of pars distalis of adenohypophysis A basophil cell of the anterior pituitary that produces thyroid stimulating hormone, thyrotrophin. This cell type is elongated, polygonal and lie in clusters towards the adenohypophyseal center. http://purl.obolibrary.org/obo/GO_0006997 nucleus organization http://purl.obolibrary.org/obo/GO_0006996 organelle organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleus. http://purl.obolibrary.org/obo/CL_0000477 follicle cell of egg chamber http://purl.obolibrary.org/obo/CL_0000500 follicular epithelial cell A somatic epithelial cell of the insect egg chamber. http://purl.obolibrary.org/obo/GO_0007005 mitochondrion organization http://purl.obolibrary.org/obo/GO_0006996 organelle organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrion; includes mitochondrial morphogenesis and distribution, and replication of the mitochondrial genome as well as synthesis of new mitochondrial components. http://purl.obolibrary.org/obo/CL_0000478 oxytocin stimulating hormone secreting cell http://purl.obolibrary.org/obo/CL_0000167 peptide hormone secreting cell A peptide hormone secreting cell that secretes oxytocin stimulating hormone http://purl.obolibrary.org/obo/GO_0007009 plasma membrane organization http://purl.obolibrary.org/obo/GO_0061024 membrane organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the plasma membrane. http://purl.obolibrary.org/obo/CL_0000479 vasopressin stimulating hormone secreting cell http://purl.obolibrary.org/obo/CL_0000167 peptide hormone secreting cell A peptide hormone secreting cell that secretes vasopressin stimulating hormone http://purl.obolibrary.org/obo/GO_0007010 cytoskeleton organization http://purl.obolibrary.org/obo/GO_0006996 organelle organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures. http://purl.obolibrary.org/obo/CL_0000480 secretin stimulating hormone secreting cell http://purl.obolibrary.org/obo/CL_0000167 peptide hormone secreting cell A peptide hormone secreting cell that secretes secretin stimulating hormone http://purl.obolibrary.org/obo/GO_0007017 microtubule-based process http://purl.obolibrary.org/obo/GO_0009987 cellular process Any cellular process that depends upon or alters the microtubule cytoskeleton, that part of the cytoskeleton comprising microtubules and their associated proteins. http://purl.obolibrary.org/obo/CL_0000481 cholecystokin stimulating hormone secreting cell http://purl.obolibrary.org/obo/CL_0000167 peptide hormone secreting cell A peptide hormone secreting cell that secretes cholecystokin stimulating hormone. http://purl.obolibrary.org/obo/GO_0007018 microtubule-based movement http://purl.obolibrary.org/obo/GO_0007017 microtubule-based process A microtubule-based process that results in the movement of organelles, other microtubules, or other cellular components. Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules. http://purl.obolibrary.org/obo/CL_0000482 juvenile hormone secreting cell http://purl.obolibrary.org/obo/CL_0000151 secretory cell An endocrine cell that secretes juvenile hormone. http://purl.obolibrary.org/obo/GO_0007033 vacuole organization http://purl.obolibrary.org/obo/GO_0006996 organelle organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vacuole. http://purl.obolibrary.org/obo/CL_0000483 bombesin stimulating hormone secreting cell http://purl.obolibrary.org/obo/CL_0000167 peptide hormone secreting cell A peptide hormone secreting cell that secretes bombesin stimulating hormone. http://purl.obolibrary.org/obo/GO_0007040 lysosome organization http://purl.obolibrary.org/obo/GO_0080171 lytic vacuole organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lysosome. A lysosome is a cytoplasmic, membrane-bounded organelle that is found in most animal cells and that contains a variety of hydrolases. http://purl.obolibrary.org/obo/CL_0000484 connective tissue type mast cell http://purl.obolibrary.org/obo/CL_0002320 connective tissue cell Mast cell subtype whose granules contain both the serine proteases tryptase and chymase. These cells are primarily found in connective tissue, such as the peritoneal cavity, skin, and intestinal submucosa. Their development is T-cell independent. http://purl.obolibrary.org/obo/GO_0007043 cell-cell junction assembly http://purl.obolibrary.org/obo/GO_0045216 cell-cell junction organization The aggregation, arrangement and bonding together of a set of components to form a junction between cells. http://purl.obolibrary.org/obo/CL_0000485 mucosal type mast cell http://purl.obolibrary.org/obo/CL_0000097 mast cell Mast cell subtype that contains only the serine protease trypase in its granules. These cells are primarily found in mucosal tissue, such as intestinal mucosa and alveoli. They depend upon T-cells for development of phenotype. http://purl.obolibrary.org/obo/GO_0007049 cell cycle http://purl.obolibrary.org/obo/GO_0009987 cellular process The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division. http://purl.obolibrary.org/obo/CL_0000486 garland cell http://purl.obolibrary.org/obo/CL_0002520 nephrocyte A large binucleate cell that forms a 'garland' around the anterior end of the proventriculus (cardia) at its junction with the esophagus in both adults and larvae flies. Each cell is surrounded by a basement membrane and there are numerous micro-invaginations (lacunae) extending from the surface into the cytoplasm. At the mouth of each lacuna is a doubled filament forming a specialised filtration system (diaphragm). The filtrate is endocytosed from the lacunae. http://purl.obolibrary.org/obo/GO_0007097 nuclear migration http://purl.obolibrary.org/obo/GO_0051656 establishment of organelle localization The directed movement of the nucleus to a specific location within a cell. http://purl.obolibrary.org/obo/CL_0000487 oenocyte http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell A secretory cell of ectodermal origin. This cell may have important functions in fatty acid and hydrocarbon metabolism and is metabolically linked to the fat body and tracheae. This cell is exclusive of arthropods. http://purl.obolibrary.org/obo/GO_0007154 cell communication http://purl.obolibrary.org/obo/GO_0009987 cellular process Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. http://purl.obolibrary.org/obo/CL_0000488 visible light photoreceptor cell http://purl.obolibrary.org/obo/CL_0000210 photoreceptor cell A photoreceptor cell that detects visible light. http://purl.obolibrary.org/obo/GO_0007155 cell adhesion http://purl.obolibrary.org/obo/GO_0009987 cellular process The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules. http://purl.obolibrary.org/obo/CL_0000492 CD4-positive helper T cell http://purl.obolibrary.org/obo/CL_0000624 CD4-positive, alpha-beta T cell A CD4-positive, alpha-beta T cell that cooperates with other lymphocytes via direct contact or cytokine release to initiate a variety of immune functions. http://purl.obolibrary.org/obo/GO_0007165 signal transduction http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell. http://purl.obolibrary.org/obo/CL_0000494 UV sensitive photoreceptor cell http://purl.obolibrary.org/obo/CL_0000210 photoreceptor cell A photoreceptor cell that detects ultraviolet light. http://purl.obolibrary.org/obo/GO_0007166 cell surface receptor signaling pathway http://purl.obolibrary.org/obo/GO_0007165 signal transduction The series of molecular signals initiated by an extracellular ligand binding to a receptor located on the cell surface. The pathway ends with regulation of a downstream cellular process, e.g. transcription. http://purl.obolibrary.org/obo/CL_0000495 blue sensitive photoreceptor cell http://purl.obolibrary.org/obo/CL_0000490 photopic photoreceptor cell A photoreceptor cell that is sensitive to blue light. http://purl.obolibrary.org/obo/GO_0007186 G protein-coupled receptor signaling pathway http://purl.obolibrary.org/obo/GO_0007165 signal transduction The series of molecular signals initiated by a ligand binding to its receptor, in which the activated receptor promotes the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, and ends with regulation of a downstream cellular process. The pathway can start from the plasma membrane, Golgi or nuclear membrane. http://purl.obolibrary.org/obo/CL_0000496 green sensitive photoreceptor cell http://purl.obolibrary.org/obo/CL_0000490 photopic photoreceptor cell A photoreceptor cell that is sensitive to green light. http://purl.obolibrary.org/obo/GO_0007267 cell-cell signaling http://purl.obolibrary.org/obo/GO_0023052 signaling Any process that mediates the transfer of information from one cell to another. This process includes signal transduction in the receiving cell and, where applicable, release of a ligand and any processes that actively facilitate its transport and presentation to the receiving cell. Examples include signaling via soluble ligands, via cell adhesion molecules and via gap junctions. http://purl.obolibrary.org/obo/CL_0000497 red sensitive photoreceptor cell http://purl.obolibrary.org/obo/CL_0000490 photopic photoreceptor cell A photoreceptor cell that is sensitive to red light. http://purl.obolibrary.org/obo/GO_0007269 neurotransmitter secretion http://purl.obolibrary.org/obo/GO_0006836 neurotransmitter transport The regulated release of neurotransmitter from the presynapse into the synaptic cleft via calcium-regulated exocytosis during synaptic transmission. http://purl.obolibrary.org/obo/CL_0000498 inhibitory interneuron http://purl.obolibrary.org/obo/CL_0000099 interneuron An interneuron (also called relay neuron, association neuron or local circuit neuron) is a multipolar neuron which connects afferent neurons and efferent neurons in neural pathways. Like motor neurons, interneuron cell bodies are always located in the central nervous system (CNS). http://purl.obolibrary.org/obo/GO_0007271 synaptic transmission, cholinergic http://purl.obolibrary.org/obo/GO_0007268 chemical synaptic transmission The vesicular release of acetylcholine from a presynapse, across a chemical synapse, the subsequent activation of dopamine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse. http://purl.obolibrary.org/obo/CL_0000499 stromal cell http://purl.obolibrary.org/obo/CL_0002320 connective tissue cell A connective tissue cell of an organ found in the loose connective tissue. http://purl.obolibrary.org/obo/GO_0007275 multicellular organism development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). http://purl.obolibrary.org/obo/CL_0000500 follicular epithelial cell http://purl.obolibrary.org/obo/CL_0000066 epithelial cell An epithelial somatic cell associated with a maturing oocyte. http://purl.obolibrary.org/obo/GO_0007286 spermatid development http://purl.obolibrary.org/obo/GO_0007281 germ cell development The process whose specific outcome is the progression of a spermatid over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/CL_0000501 granulosa cell http://purl.obolibrary.org/obo/CL_0002174 follicular cell of ovary A supporting cell for the developing female gamete in the ovary of mammals. They develop from the coelomic epithelial cells of the gonadal ridge. Granulosa cells form a single layer around the mammalian oocyte in the primordial ovarian follicle and advance to form a multilayered cumulus oophorus surrounding the ovum in the Graafian follicle. The major functions of granulosa cells include the production of steroids and LH receptors. http://purl.obolibrary.org/obo/GO_0007369 gastrulation http://purl.obolibrary.org/obo/GO_0048598 embryonic morphogenesis A complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals. The details of gastrulation vary from species to species, but usually result in the formation of the three primary germ layers, ectoderm, mesoderm and endoderm. http://purl.obolibrary.org/obo/CL_0000502 type D enteroendocrine cell http://purl.obolibrary.org/obo/CL_0000172 somatostatin secreting cell A cell found throughout the gastrointestinal tract and in the pancreas. They secrete somatostatin in both an endocrine and paracrine manner. Somatostatin inhibits gastrin, cholecystokinin, insulin, glucagon, pancreatic enzymes, and gastric hydrochloric acid. A variety of substances which inhibit gastric acid secretion (vasoactive intestinal peptide, calcitonin gene-related peptide, cholecystokinin, beta-adrenergic agonists, and gastric inhibitory peptide) are thought to act by releasing somatostatin. http://purl.obolibrary.org/obo/GO_0007389 pattern specification process http://purl.obolibrary.org/obo/GO_0032501 multicellular organismal process Any developmental process that results in the creation of defined areas or spaces within an organism to which cells respond and eventually are instructed to differentiate. http://purl.obolibrary.org/obo/CL_0000503 theca cell http://purl.obolibrary.org/obo/CL_0002174 follicular cell of ovary A specialized stromal cell that forms the theca layer outside the basal lamina lining the ovarian follicle, appearing during the secondary follicle stage. http://purl.obolibrary.org/obo/GO_0007398 ectoderm development http://purl.obolibrary.org/obo/GO_0009888 tissue development The process whose specific outcome is the progression of the ectoderm over time, from its formation to the mature structure. In animal embryos, the ectoderm is the outer germ layer of the embryo, formed during gastrulation. http://purl.obolibrary.org/obo/CL_0000504 enterochromaffin-like cell http://purl.obolibrary.org/obo/CL_0002274 histamine secreting cell A enteroendocrine cell part of the glands of the gastric mucosa. They produce histamine and peptides such as chromogranins. This cell type respond to gastrin by releasing histamine which acts as a paracrine stimulator of the release of hydrochloric acid from the gastric parietal cells. http://purl.obolibrary.org/obo/GO_0007405 neuroblast proliferation http://purl.obolibrary.org/obo/GO_0061351 neural precursor cell proliferation The expansion of a neuroblast population by cell division. A neuroblast is any cell that will divide and give rise to a neuron. http://purl.obolibrary.org/obo/CL_0000505 substance P secreting cell http://purl.obolibrary.org/obo/CL_0000167 peptide hormone secreting cell A peptide hormone secreting cell that secretes substance P. http://purl.obolibrary.org/obo/GO_0007423 sensory organ development http://purl.obolibrary.org/obo/GO_0048513 animal organ development The process whose specific outcome is the progression of sensory organs over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/CL_0000506 enkephalin secreting cell http://purl.obolibrary.org/obo/CL_0000507 endorphin secreting cell An endorphine cell that secretes enkephalin. http://purl.obolibrary.org/obo/GO_0007492 endoderm development http://purl.obolibrary.org/obo/GO_0009888 tissue development The process whose specific outcome is the progression of the endoderm over time, from its formation to the mature structure. The endoderm is the innermost germ layer that develops into the gastrointestinal tract, the lungs and associated tissues. http://purl.obolibrary.org/obo/CL_0000507 endorphin secreting cell http://purl.obolibrary.org/obo/CL_0000167 peptide hormone secreting cell A peptide hormone secreting cell that secretes endorphin. http://purl.obolibrary.org/obo/GO_0007507 heart development http://purl.obolibrary.org/obo/GO_0048513 animal organ development The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. http://purl.obolibrary.org/obo/CL_0000508 type G enteroendocrine cell http://purl.obolibrary.org/obo/CL_0000509 gastrin secreting cell An endocrine cell found in the stomach and duodenum and is responsible for the secretion of gastrin and enkephalin. Most abundant in pyloric antrum, pyramidal in form with a narrow apex bearing long microvilli. http://purl.obolibrary.org/obo/GO_0007519 skeletal muscle tissue development http://purl.obolibrary.org/obo/GO_0014706 striated muscle tissue development The developmental sequence of events leading to the formation of adult skeletal muscle tissue. The main events are: the fusion of myoblasts to form myotubes that increase in size by further fusion to them of myoblasts, the formation of myofibrils within their cytoplasm and the establishment of functional neuromuscular junctions with motor neurons. At this stage they can be regarded as mature muscle fibers. http://purl.obolibrary.org/obo/CL_0000509 gastrin secreting cell http://purl.obolibrary.org/obo/CL_0000167 peptide hormone secreting cell A peptide hormone secreting cell that secretes gastrin. http://purl.obolibrary.org/obo/GO_0007585 respiratory gaseous exchange by respiratory system http://purl.obolibrary.org/obo/GO_0032501 multicellular organismal process The process of gaseous exchange between an organism and its environment. In plants, microorganisms, and many small animals, air or water makes direct contact with the organism's cells or tissue fluids, and the processes of diffusion supply the organism with dioxygen (O2) and remove carbon dioxide (CO2). In larger animals the efficiency of gaseous exchange is improved by specialized respiratory organs, such as lungs and gills, which are ventilated by breathing mechanisms. http://purl.obolibrary.org/obo/CL_0000510 paneth cell http://purl.obolibrary.org/obo/CL_0002563 intestinal epithelial cell An epithelial cell found in the basal part of the intestinal glands (crypts of Lieberkuhn) including the appendix. Paneth cells synthesize and secrete lysozyme and cryptdins. Numerous in the deeper parts of the intestinal crypts, particularly in the duodenum, rich in zinc, contain large acidophilic granules, with irregular apical microvilli and prominent membrane-bound vacuoles containing matrix. http://purl.obolibrary.org/obo/GO_0007610 behavior http://purl.obolibrary.org/obo/GO_0032501 multicellular organismal process The internally coordinated responses (actions or inactions) of animals (individuals or groups) to internal or external stimuli, via a mechanism that involves nervous system activity. http://purl.obolibrary.org/obo/CL_0000511 androgen binding protein secreting cell http://purl.obolibrary.org/obo/CL_0000154 protein secreting cell A peptide hormone secreting cell that secretes androgen binding protein. http://purl.obolibrary.org/obo/GO_0008016 regulation of heart contraction http://purl.obolibrary.org/obo/GO_1903522 regulation of blood circulation Any process that modulates the frequency, rate or extent of heart contraction. Heart contraction is the process in which the heart decreases in volume in a characteristic way to propel blood through the body. http://purl.obolibrary.org/obo/CL_0000513 cardiac muscle myoblast http://purl.obolibrary.org/obo/CL_0010021 cardiac myoblast A precursor cell destined to differentiate into cardiac muscle cell. http://purl.obolibrary.org/obo/GO_0008092 cytoskeletal protein binding http://purl.obolibrary.org/obo/GO_0005515 protein binding Binding to a protein component of a cytoskeleton (actin, microtubule, or intermediate filament cytoskeleton). http://purl.obolibrary.org/obo/CL_0000514 smooth muscle myoblast http://purl.obolibrary.org/obo/CL_0000056 myoblast A precursor cell destined to differentiate into smooth muscle myocytes. http://purl.obolibrary.org/obo/GO_0008094 ATP-dependent activity, acting on DNA http://purl.obolibrary.org/obo/GO_0140657 ATP-dependent activity Catalytic activity that acts to modify DNA, driven by ATP hydrolysis. http://purl.obolibrary.org/obo/CL_0000515 skeletal muscle myoblast http://purl.obolibrary.org/obo/CL_0000056 myoblast A myoblast that differentiates into skeletal muscle fibers. http://purl.obolibrary.org/obo/GO_0008134 transcription factor binding http://purl.obolibrary.org/obo/GO_0005515 protein binding Binding to a transcription factor, a protein required to initiate or regulate transcription. http://purl.obolibrary.org/obo/CL_0000516 perineuronal satellite cell http://purl.obolibrary.org/obo/CL_0000123 neuron associated cell (sensu Vertebrata) A non-neuronal cell that surrounds the neuronal cell bodies of the ganglia. http://purl.obolibrary.org/obo/GO_0008186 ATP-dependent activity, acting on RNA http://purl.obolibrary.org/obo/GO_0140657 ATP-dependent activity Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction requires the presence of RNA, and it drives another reaction. http://purl.obolibrary.org/obo/CL_0000517 macrophage derived foam cell http://purl.obolibrary.org/obo/CL_0000891 foam cell A type of foam cell derived from a macrophage containing lipids in small vacuoles and typically seen in atherolosclerotic lesions, as well as other conditions. http://purl.obolibrary.org/obo/GO_0008188 neuropeptide receptor activity http://purl.obolibrary.org/obo/GO_0008528 G protein-coupled peptide receptor activity Combining with a neuropeptide to initiate a change in cell activity. http://purl.obolibrary.org/obo/CL_0000518 phagocyte (sensu Vertebrata) http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell A phagocyte in vertebrates that is able to phagocytosis. http://purl.obolibrary.org/obo/GO_0008206 bile acid metabolic process http://purl.obolibrary.org/obo/GO_0032787 monocarboxylic acid metabolic process The chemical reactions and pathways involving bile acids, a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine. http://purl.obolibrary.org/obo/CL_0000519 phagocyte (sensu Nematoda and Protostomia) http://purl.obolibrary.org/obo/CL_0000234 phagocyte A phagocyte from organisms in the Nematoda or Protostomia clades. http://purl.obolibrary.org/obo/GO_0008217 regulation of blood pressure http://purl.obolibrary.org/obo/GO_0065008 regulation of biological quality Any process that modulates the force with which blood travels through the circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure. http://purl.obolibrary.org/obo/CL_0000521 fungal cell http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell Any cell that in taxon some Fungi. http://purl.obolibrary.org/obo/GO_0008227 G protein-coupled amine receptor activity http://purl.obolibrary.org/obo/GO_0004930 G protein-coupled receptor activity Combining with an extracellular amine and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. http://purl.obolibrary.org/obo/CL_0000523 mononuclear cytotrophoblast cell http://purl.obolibrary.org/obo/CL_0000351 trophoblast cell A cell from the inner layer of the trophoblast of the early mammalian embryo that gives rise to the outer surface and villi of the chorion. Mononuclear crytoblasts fuse to give rise to a multinuclear cytotrophoblast. http://purl.obolibrary.org/obo/GO_0008283 cell population proliferation http://purl.obolibrary.org/obo/GO_0009987 cellular process The multiplication or reproduction of cells, resulting in the expansion of a cell population. http://purl.obolibrary.org/obo/CL_0000524 spheroplast http://purl.obolibrary.org/obo/CL_0000371 protoplast A cell, usually of bacteria or yeast, which has partially lost its cell wall. http://purl.obolibrary.org/obo/GO_0008284 positive regulation of cell population proliferation http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the rate or extent of cell proliferation. http://purl.obolibrary.org/obo/CL_0000525 syncytiotrophoblast cell http://purl.obolibrary.org/obo/CL_0000351 trophoblast cell A cell from the outer syncytial layer of the trophoblast of an early mammalian embryo, directly associated with the maternal blood supply. It secretes hCG in order to maintain progesterone secretion and sustain a pregnancy. http://purl.obolibrary.org/obo/GO_0008289 lipid binding http://purl.obolibrary.org/obo/GO_0005488 binding Binding to a lipid. http://purl.obolibrary.org/obo/CL_0000526 afferent neuron http://purl.obolibrary.org/obo/CL_0000540 neuron A neuron which conveys sensory information centrally from the periphery. http://purl.obolibrary.org/obo/GO_0008306 associative learning http://purl.obolibrary.org/obo/GO_0007612 learning Learning by associating a stimulus (the cause) with a particular outcome (the effect). http://purl.obolibrary.org/obo/CL_0000527 efferent neuron http://purl.obolibrary.org/obo/CL_0000540 neuron A neuron which sends impulses peripherally to activate muscles or secretory cells. http://purl.obolibrary.org/obo/GO_0008324 monoatomic cation transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0015075 monoatomic ion transmembrane transporter activity Enables the transfer of cation from one side of a membrane to the other. http://purl.obolibrary.org/obo/CL_0000528 nitrergic neuron http://purl.obolibrary.org/obo/CL_0000540 neuron A nerve cell where transmission is mediated by nitric oxide. http://purl.obolibrary.org/obo/GO_0008348 negative regulation of antimicrobial humoral response http://purl.obolibrary.org/obo/GO_0032102 negative regulation of response to external stimulus Any process that stops, prevents, or reduces the frequency, rate, or extent of an antimicrobial humoral response. http://purl.obolibrary.org/obo/CL_0000530 primary neuron (sensu Teleostei) http://purl.obolibrary.org/obo/CL_2000029 central nervous system neuron A neuron that develops during the early segmentation stages in teleosts, before the neural tube is formed. http://purl.obolibrary.org/obo/GO_0008519 ammonium channel activity http://purl.obolibrary.org/obo/GO_0015267 channel activity Enables the energy-independent facilitated diffusion of ammonium through a transmembrane aqueous pore or channel. http://purl.obolibrary.org/obo/CL_0000531 primary sensory neuron (sensu Teleostei) http://purl.obolibrary.org/obo/CL_0000530 primary neuron (sensu Teleostei) A primary neuron (sensu Teleostei) that has a sensory function. http://purl.obolibrary.org/obo/GO_0008528 G protein-coupled peptide receptor activity http://purl.obolibrary.org/obo/GO_0004930 G protein-coupled receptor activity Combining with a peptide and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. http://purl.obolibrary.org/obo/CL_0000532 CAP motoneuron http://purl.obolibrary.org/obo/CL_0000533 primary motor neuron (sensu Teleostei) A primary motor neuron with its soma in the caudal region of a spinal cord. The axon of this motoneuron exit the spinal cord from one single point and innervates the lateral surface of ventral axial muscles http://purl.obolibrary.org/obo/GO_0008585 female gonad development http://purl.obolibrary.org/obo/GO_0008406 gonad development The process whose specific outcome is the progression of the female gonad over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/CL_0000533 primary motor neuron (sensu Teleostei) http://purl.obolibrary.org/obo/CL_0011001 spinal cord motor neuron A primary neuron (sensu Teleostei) that has a motor function. http://purl.obolibrary.org/obo/GO_0008652 amino acid biosynthetic process http://purl.obolibrary.org/obo/GO_0009058 biosynthetic process The chemical reactions and pathways resulting in the formation of amino acids, organic acids containing one or more amino substituents. http://purl.obolibrary.org/obo/CL_0000534 primary interneuron (sensu Teleostei) http://purl.obolibrary.org/obo/CL_0005000 spinal cord interneuron A primary neuron (sensu Teleostei) that is neither a sensory neuron or a motor neuron. http://purl.obolibrary.org/obo/GO_0009057 macromolecule catabolic process http://purl.obolibrary.org/obo/GO_0009056 catabolic process The chemical reactions and pathways resulting in the breakdown of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. http://purl.obolibrary.org/obo/CL_0000535 secondary neuron (sensu Teleostei) http://purl.obolibrary.org/obo/CL_2000029 central nervous system neuron A neuron of teleosts that develops later than a primary neuron, typically during the larval stages. http://purl.obolibrary.org/obo/GO_0009058 biosynthetic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process A cellular process consisting of the biochemical pathways by which a living organism synthesizes chemical substances. This typically represents the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones. http://purl.obolibrary.org/obo/CL_0000536 secondary motor neuron (sensu Teleostei) http://purl.obolibrary.org/obo/CL_0011001 spinal cord motor neuron A secondary neuron (sensu Teleostei) that has a motor function. http://purl.obolibrary.org/obo/GO_0009059 macromolecule biosynthetic process http://purl.obolibrary.org/obo/GO_0009058 biosynthetic process The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. http://purl.obolibrary.org/obo/CL_0000540 neuron http://purl.obolibrary.org/obo/CL_0002319 neural cell The basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system. http://purl.obolibrary.org/obo/GO_0009062 fatty acid catabolic process http://purl.obolibrary.org/obo/GO_0006631 fatty acid metabolic process The chemical reactions and pathways resulting in the breakdown of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes. http://purl.obolibrary.org/obo/CL_0000541 melanoblast http://purl.obolibrary.org/obo/CL_0011026 progenitor cell A cell that originates from the neural crest and differentiates into a pigment cell. http://purl.obolibrary.org/obo/GO_0009063 amino acid catabolic process http://purl.obolibrary.org/obo/GO_0009056 catabolic process The chemical reactions and pathways resulting in the breakdown of amino acids, organic acids containing one or more amino substituents. http://purl.obolibrary.org/obo/CL_0000542 lymphocyte http://purl.obolibrary.org/obo/CL_0000842 mononuclear leukocyte A lymphocyte is a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin. http://purl.obolibrary.org/obo/GO_0009073 aromatic amino acid family biosynthetic process http://purl.obolibrary.org/obo/GO_0046394 carboxylic acid biosynthetic process The chemical reactions and pathways resulting in the formation of aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan). http://purl.obolibrary.org/obo/CL_0000545 T-helper 1 cell http://purl.obolibrary.org/obo/CL_0000492 CD4-positive helper T cell A CD4-positive, alpha-beta T cell that has the phenotype T-bet-positive, CXCR3-positive, CCR6-negative, and is capable of producing interferon-gamma. http://purl.obolibrary.org/obo/GO_0009074 aromatic amino acid family catabolic process http://purl.obolibrary.org/obo/GO_0046395 carboxylic acid catabolic process The chemical reactions and pathways resulting in the breakdown of aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan). http://purl.obolibrary.org/obo/CL_0000546 T-helper 2 cell http://purl.obolibrary.org/obo/CL_0001051 CD4-positive, CXCR3-negative, CCR6-negative, alpha-beta T cell A CD4-positive, alpha-beta T cell that has the phenotype GATA-3-positive, CXCR3-negative, CCR6-negative, and is capable of producing interleukin-4. http://purl.obolibrary.org/obo/GO_0009306 protein secretion http://purl.obolibrary.org/obo/GO_0071692 protein localization to extracellular region The controlled release of proteins from a cell. http://purl.obolibrary.org/obo/CL_0000547 proerythroblast http://purl.obolibrary.org/obo/CL_0002242 nucleate cell An immature, nucleated erythrocyte occupying the stage of erythropoeisis that follows formation of erythroid progenitor cells. This cell is CD71-positive, has both a nucleus and a nucleolus, and lacks hematopoeitic lineage markers. http://purl.obolibrary.org/obo/GO_0009536 plastid http://purl.obolibrary.org/obo/GO_0043231 intracellular membrane-bounded organelle Any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid. http://purl.obolibrary.org/obo/CL_0000549 basophilic erythroblast http://purl.obolibrary.org/obo/CL_0000765 erythroblast A nucleated immature erythrocyte, having cytoplasm generally similar to that of the earlier proerythroblast but sometimes even more basophilic, and usually regular in outline. The nucleus is still relatively large, but the chromatin strands are thicker and more deeply staining, giving a coarser appearance; the nucleoli have disappeared. This cell is CD71-positive and lacks hematopoeitic lineage markers. http://purl.obolibrary.org/obo/GO_0009547 plastid ribosome http://purl.obolibrary.org/obo/GO_0000313 organellar ribosome A ribosome contained within a plastid. http://purl.obolibrary.org/obo/CL_0000550 polychromatophilic erythroblast http://purl.obolibrary.org/obo/CL_0000765 erythroblast A nucleated, immature erythrocyte in which the nucleus occupies a relatively smaller part of the cell than in its precursor, the basophilic erythroblast. The cytoplasm is beginning to acquire hemoglobin and thus is no longer a purely basophilic, but takes on acidophilic aspects, which becomes progressively more marked as the cell matures. The chromatin of the nucleus is arranged in coarse, deeply staining clumps. This cell is CD71-positive and lacks hematopoeitic lineage markers. http://purl.obolibrary.org/obo/GO_0009593 detection of chemical stimulus http://purl.obolibrary.org/obo/GO_0051606 detection of stimulus The series of events in which a chemical stimulus is received by a cell and converted into a molecular signal. http://purl.obolibrary.org/obo/CL_0000552 orthochromatic erythroblast http://purl.obolibrary.org/obo/CL_0000765 erythroblast The final stage of the nucleated, immature erythrocyte, before nuclear loss. Typically the cytoplasm is described as acidophilic, but it still shows a faint polychromatic tint. The nucleus is small and initially may still have coarse, clumped chromatin, as in its precursor, the polychromatophilic erythroblast, but ultimately it becomes pyknotic, and appears as a deeply staining, blue-black, homogeneous structureless mass. The nucleus is often eccentric and sometimes lobulated. http://purl.obolibrary.org/obo/GO_0009605 response to external stimulus http://purl.obolibrary.org/obo/GO_0050896 response to stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus. http://purl.obolibrary.org/obo/CL_0000553 megakaryocyte progenitor cell http://purl.obolibrary.org/obo/CL_0000839 myeloid lineage restricted progenitor cell The earliest cytologically identifiable precursor in the thrombocytic series. This cell is capable of endomitosis and lacks expression of hematopoieitic lineage markers (lin-negative). http://purl.obolibrary.org/obo/GO_0009607 response to biotic stimulus http://purl.obolibrary.org/obo/GO_0050896 response to stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotic stimulus, a stimulus caused or produced by a living organism. http://purl.obolibrary.org/obo/CL_0000554 gastrin stimulating hormone secreting cell http://purl.obolibrary.org/obo/CL_0000167 peptide hormone secreting cell A peptide hormone secreting cell that secretes gastrin stimulating hormone. http://purl.obolibrary.org/obo/GO_0009611 response to wounding http://purl.obolibrary.org/obo/GO_0006950 response to stress Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism. http://purl.obolibrary.org/obo/CL_0000556 megakaryocyte http://purl.obolibrary.org/obo/CL_0000763 myeloid cell A large hematopoietic cell (50 to 100 micron) with a lobated nucleus. Once mature, this cell undergoes multiple rounds of endomitosis and cytoplasmic restructuring to allow platelet formation and release. http://purl.obolibrary.org/obo/GO_0009617 response to bacterium http://purl.obolibrary.org/obo/GO_0051707 response to other organism Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a bacterium. http://purl.obolibrary.org/obo/CL_0000557 granulocyte monocyte progenitor cell http://purl.obolibrary.org/obo/CL_1001610 bone marrow hematopoietic cell A hematopoietic progenitor cell that is committed to the granulocyte and monocyte lineages. These cells are CD123-positive, and do not express Gata1 or Gata2 but do express C/EBPa, and Pu.1. http://purl.obolibrary.org/obo/GO_0009620 response to fungus http://purl.obolibrary.org/obo/GO_0051707 response to other organism Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a fungus. http://purl.obolibrary.org/obo/CL_0000558 reticulocyte http://purl.obolibrary.org/obo/CL_0000764 erythroid lineage cell An immature erythrocyte that changes the protein composition of its plasma membrane by exosome formation and extrusion. The types of protein removed differ between species though removal of the transferrin receptor is apparent in mammals and birds. http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis http://purl.obolibrary.org/obo/GO_0032502 developmental process The process in which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form. http://purl.obolibrary.org/obo/CL_0000559 promonocyte http://purl.obolibrary.org/obo/CL_0002194 monopoietic cell A precursor in the monocytic series, being a cell intermediate in development between the monoblast and monocyte. This cell is CD11b-positive and has fine azurophil granules. http://purl.obolibrary.org/obo/GO_0009755 hormone-mediated signaling pathway http://purl.obolibrary.org/obo/GO_0007165 signal transduction The series of molecular signals mediated by the detection of a hormone. http://purl.obolibrary.org/obo/CL_0000560 band form neutrophil http://purl.obolibrary.org/obo/CL_0000096 mature neutrophil A late neutrophilic metamyelocyte in which the nucleus is indented to more than half the distance to the farthest nuclear margin but in no area being condensed to a single filament. The nucleus is in the form of a curved or coiled band, not having acquired the typical multilobar shape of the mature neutrophil. These cells are fMLP receptor-positive, CD11b-positive, CD35-negative, and CD49d-negative. http://purl.obolibrary.org/obo/GO_0009791 post-embryonic development http://purl.obolibrary.org/obo/GO_0032501 multicellular organismal process The process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. See embryonic development. http://purl.obolibrary.org/obo/CL_0000561 amacrine cell http://purl.obolibrary.org/obo/CL_0009004 retinal cell Interneuron of the vertebrate retina. They integrate, modulate, and interpose a temporal domain in the visual message presented to the retinal ganglion cells, with which they synapse in the inner plexiform layer. They lack large axons. http://purl.obolibrary.org/obo/GO_0009792 embryo development ending in birth or egg hatching http://purl.obolibrary.org/obo/GO_0009790 embryo development The process whose specific outcome is the progression of an embryo over time, from zygote formation until the end of the embryonic life stage. The end of the embryonic life stage is organism-specific and may be somewhat arbitrary; for mammals it is usually considered to be birth, for insects the hatching of the first instar larva from the eggshell. http://purl.obolibrary.org/obo/CL_0000562 nucleate erythrocyte http://purl.obolibrary.org/obo/CL_0002242 nucleate cell An erythrocyte having a nucleus. http://purl.obolibrary.org/obo/GO_0009798 axis specification http://purl.obolibrary.org/obo/GO_0007389 pattern specification process The establishment, maintenance and elaboration of a pattern along a line or around a point. http://purl.obolibrary.org/obo/CL_0000563 endospore http://purl.obolibrary.org/obo/CL_0000520 prokaryotic cell A rounded, inactive form that certain bacteria assume under conditions of extreme temperature, dryness, or lack of food. The bacterium develops a waterproof cell wall that protects it from being dried out or damaged. http://purl.obolibrary.org/obo/CL_0000564 neutrophilic promyelocyte http://purl.obolibrary.org/obo/CL_0000836 promyelocyte A promyelocyte committed to the neutrophil lineage. This cell type is GATA-1-positive, C/EBPa-positive, AML-1-positive, MPO-positive, has low expression of PU.1 transcription factor and lacks lactotransferrin expression. http://purl.obolibrary.org/obo/GO_0009880 embryonic pattern specification http://purl.obolibrary.org/obo/GO_0007389 pattern specification process The process that results in the patterns of cell differentiation that will arise in an embryo. http://purl.obolibrary.org/obo/CL_0000565 fat body cell http://purl.obolibrary.org/obo/CL_0000325 stuff accumulating cell A cell found in fat bodies whose primary function is intermediary metabolism. http://purl.obolibrary.org/obo/GO_0009886 post-embryonic animal morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process, occurring after animal embryonic development, by which anatomical structures are generated and organized. http://purl.obolibrary.org/obo/CL_0000566 angioblastic mesenchymal cell http://purl.obolibrary.org/obo/CL_0011026 progenitor cell A mesenchymal stem cell capable of developing into blood vessel endothelium. http://purl.obolibrary.org/obo/GO_0009887 animal organ morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis Morphogenesis of an animal organ. An organ is defined as a tissue or set of tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. http://purl.obolibrary.org/obo/CL_0000568 amine precursor uptake and decarboxylation cell http://purl.obolibrary.org/obo/CL_0000165 neuroendocrine cell A cell that originates in the neural crest, that has certain cytochemical and ultrastructural characteristics and is found scattered throughout the body; types include melanocytes, the cells of the chromaffin system, and cells in the hypothalamus, hypophysis, thyroid, parathyroids, lungs, gastrointestinal tract, and pancreas. This cell type concentrates the amino acid precursors of certain amines and decarboxylate them, forming amines that function as regulators and neurotransmitters. This cell type produces substances such as epinephrine, norepinephrine, dopamine, serotonin, enkephalin, somatostatin, neurotensin, and substance P, the actions of which may affect contiguous cells, nearby groups of cells, or distant cells, thus functioning as local or systemic hormones. The name is an acronym for amine precursor uptake and decarboxylation cell. http://purl.obolibrary.org/obo/GO_0009888 tissue development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of a tissue over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0009913 epidermal cell differentiation http://purl.obolibrary.org/obo/GO_0030855 epithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of an epidermal cell, any of the cells making up the epidermis. http://purl.obolibrary.org/obo/CL_0000569 cardiac mesenchymal cell http://purl.obolibrary.org/obo/CL_2000073 migratory cardiac neural crest cell A mesenchymal cell found in the developing heart and that develops into some part of the heart. These cells derive from intra- and extra-cardiac sources, including the endocardium, epicardium, neural crest, and second heart field. http://purl.obolibrary.org/obo/GO_0009914 hormone transport http://purl.obolibrary.org/obo/GO_0010817 regulation of hormone levels The directed movement of hormones into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/CL_0000570 parafollicular cell http://purl.obolibrary.org/obo/CL_0002257 epithelial cell of thyroid gland A neuroepithelial cells that occurs singly or in small groups, close to the outer follicular borders but within the follicular basement membrane of the thyroid. This cell expresses a form of the neural cell adhesion molecule (N-CAM) on its surface and secretes calcitonin and serotonin (5-hydroxytryptamine). http://purl.obolibrary.org/obo/GO_0009952 anterior/posterior pattern specification http://purl.obolibrary.org/obo/GO_0003002 regionalization The regionalization process in which specific areas of cell differentiation are determined along the anterior-posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism. http://purl.obolibrary.org/obo/CL_0000571 leucophore http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell A pigment cell derived from the neural crest. Contains uric acid or other purine crystals deposited in stacks called leucosomes. The crystals reflect light and this gives a white appearance under white light. http://purl.obolibrary.org/obo/GO_0009966 regulation of signal transduction http://purl.obolibrary.org/obo/GO_0048583 regulation of response to stimulus Any process that modulates the frequency, rate or extent of signal transduction. http://purl.obolibrary.org/obo/CL_0000573 retinal cone cell http://purl.obolibrary.org/obo/CL_0010009 camera-type eye photoreceptor cell One of the two photoreceptor cell types in the vertebrate retina. In cones the photopigment is in invaginations of the cell membrane of the outer segment. Cones are less sensitive to light than rods, but they provide vision with higher spatial and temporal acuity, and the combination of signals from cones with different pigments allows color vision. http://purl.obolibrary.org/obo/GO_0009967 positive regulation of signal transduction http://purl.obolibrary.org/obo/GO_0010647 positive regulation of cell communication Any process that activates or increases the frequency, rate or extent of signal transduction. http://purl.obolibrary.org/obo/GO_0009968 negative regulation of signal transduction http://purl.obolibrary.org/obo/GO_0010648 negative regulation of cell communication Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction. http://purl.obolibrary.org/obo/CL_0000574 erythrophore http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell A pigment cell derived from the neural crest. Contains pteridine and/or carotenoid pigments in structures called pterinosomes or erythrosomes. This gives an orange to red appearance. http://purl.obolibrary.org/obo/GO_0009987 cellular process http://purl.obolibrary.org/obo/GO_0008150 biological_process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. http://purl.obolibrary.org/obo/CL_0000575 corneal epithelial cell http://purl.obolibrary.org/obo/CL_0002159 general ecto-epithelial cell An epithelial cell of the cornea. http://purl.obolibrary.org/obo/GO_0010001 glial cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a glial cell. http://purl.obolibrary.org/obo/CL_0000576 monocyte http://purl.obolibrary.org/obo/CL_0011026 progenitor cell Myeloid mononuclear recirculating leukocyte that can act as a precursor of tissue macrophages, osteoclasts and some populations of tissue dendritic cells. http://purl.obolibrary.org/obo/GO_0010002 cardioblast differentiation http://purl.obolibrary.org/obo/GO_0048863 stem cell differentiation The process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. http://purl.obolibrary.org/obo/CL_0000577 type EC enteroendocrine cell http://purl.obolibrary.org/obo/CL_0000506 enkephalin secreting cell A subtype of enteroendocrine cells found in the gastrointestinal mucosa, particularly in the glands of pyloric antrum; duodenum; and ileum. These cell type secretes serotonin and some neurotransmitters including enkephalins and substance P. Their secretory granules stain readily with silver (argentaffin stain). http://purl.obolibrary.org/obo/GO_0010463 mesenchymal cell proliferation http://purl.obolibrary.org/obo/GO_0008283 cell population proliferation The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets. http://purl.obolibrary.org/obo/CL_0000578 experimentally modified cell in vitro http://purl.obolibrary.org/obo/CL_0001034 cell in vitro A cell in vitro that has undergone physical changes as a consequence of a deliberate and specific experimental procedure. http://purl.obolibrary.org/obo/GO_0010464 regulation of mesenchymal cell proliferation http://purl.obolibrary.org/obo/GO_0042127 regulation of cell population proliferation Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets. http://purl.obolibrary.org/obo/CL_0000579 border follicle cell http://purl.obolibrary.org/obo/CL_0000477 follicle cell of egg chamber A follicle cell that migrates from the anterior pole of the insect egg chamber to the anterior of the oocyte where they participate in the formation of the micropyle. http://purl.obolibrary.org/obo/GO_0010467 gene expression http://purl.obolibrary.org/obo/GO_0009059 macromolecule biosynthetic process The process in which a gene's sequence is converted into a mature gene product (protein or RNA). This includes the production of an RNA transcript and its processing, as well as translation and maturation for protein-coding genes. http://purl.obolibrary.org/obo/CL_0000580 neutrophilic myelocyte http://purl.obolibrary.org/obo/CL_0002193 myelocyte A neutrophil precursor in the granulocytic series, being a cell intermediate in development between a promyelocyte and a metamyelocyte; in this stage, production of primary granules is complete and neutrophil-specific granules has started. No nucleolus is present. This cell type is CD13-positive, CD16-negative, integrin alpha-M-positive, CD15-positive, CD33-positive, CD24-positive, C/EBP-a-positive, C/EBPe-positive, PU.1-positive, lactotransferrin-positive, myeloperoxidase-positive and NGAL-positive. http://purl.obolibrary.org/obo/GO_0010468 regulation of gene expression http://purl.obolibrary.org/obo/GO_0010556 regulation of macromolecule biosynthetic process Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA). http://purl.obolibrary.org/obo/CL_0000581 peritoneal macrophage http://purl.obolibrary.org/obo/CL_0000864 tissue-resident macrophage A macrophage resident in the peritoneum under non-inflammatory conditions. Markers include F4/80-high, CD11b-high, CD68-positive, SIGNR1-positive, CD115-high, MHC-II-negative, and Dectin-1-positive. http://purl.obolibrary.org/obo/GO_0010556 regulation of macromolecule biosynthetic process http://purl.obolibrary.org/obo/GO_0009889 regulation of biosynthetic process Any process that modulates the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. http://purl.obolibrary.org/obo/CL_0000582 neutrophilic metamyelocyte http://purl.obolibrary.org/obo/CL_0002192 metamyelocyte A neutrophil precursor in the granulocytic series, being a cell intermediate in development between a myelocyte and the band form neutrophil. The protein synthesis seen in earlier stages decreases or stops; the nucleus becomes indented where the indentation is smaller than half the distance to the farthest nuclear margin; chromatin becomes coarse and clumped; specific granules predominate while primary granules are rare; and the cytoplasm becomes amphophilic like that of a mature granulocyte. This cell type is integrin alpha-M-positive, CD13-negative, CD15-positive, CD16-positive, CD33-positive, CD24-positive, fMLP receptor-negative and has expression of C/EBP-a, C/EBP-e, PU.1 transcription factor, lactotransferrin, myeloperoxidase and neutrophil gelatinase associated lipocalin. http://purl.obolibrary.org/obo/GO_0010557 positive regulation of macromolecule biosynthetic process http://purl.obolibrary.org/obo/GO_0009891 positive regulation of biosynthetic process Any process that increases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. http://purl.obolibrary.org/obo/CL_0000583 alveolar macrophage http://purl.obolibrary.org/obo/CL_1001603 lung macrophage A tissue-resident macrophage found in the alveoli of the lungs. Ingests small inhaled particles resulting in degradation and presentation of the antigen to immunocompetent cells. Markers include F4/80-positive, CD11b-/low, CD11c-positive, CD68-positive, sialoadhesin-positive, dectin-1-positive, MR-positive, CX3CR1-negative. http://purl.obolibrary.org/obo/GO_0010558 negative regulation of macromolecule biosynthetic process http://purl.obolibrary.org/obo/GO_0009890 negative regulation of biosynthetic process Any process that decreases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. http://purl.obolibrary.org/obo/CL_0000584 enterocyte http://purl.obolibrary.org/obo/CL_0002563 intestinal epithelial cell An epithelial cell that has its apical plasma membrane folded into microvilli to provide ample surface for the absorption of nutrients from the intestinal lumen. http://purl.obolibrary.org/obo/GO_0010604 positive regulation of macromolecule metabolic process http://purl.obolibrary.org/obo/GO_0009893 positive regulation of metabolic process Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. http://purl.obolibrary.org/obo/CL_0000586 germ cell http://purl.obolibrary.org/obo/CL_0000039 germ line cell The reproductive cell in multicellular organisms. http://purl.obolibrary.org/obo/GO_0010605 negative regulation of macromolecule metabolic process http://purl.obolibrary.org/obo/GO_0009892 negative regulation of metabolic process Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. http://purl.obolibrary.org/obo/CL_0000587 cold sensing thermoreceptor cell http://purl.obolibrary.org/obo/CL_0000205 thermoreceptor cell A thermoreceptor cell that detects reduced temperatures. http://purl.obolibrary.org/obo/GO_0010646 regulation of cell communication http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. http://purl.obolibrary.org/obo/CL_0000588 odontoclast http://purl.obolibrary.org/obo/CL_0000092 osteoclast A specialized osteoclast associated with the absorption and removal of cementum. http://purl.obolibrary.org/obo/GO_0010668 ectodermal cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features of an ectodermal cell. Differentiation includes the processes involved in commitment of a cell to a specific fate. http://purl.obolibrary.org/obo/CL_0000589 cochlear inner hair cell http://purl.obolibrary.org/obo/CL_4023120 cochlea auditory hair cell A bulbous cell that is medially placed in one row in the organ of Corti. In contrast to the outer hair cells, the inner hair cells are fewer in number, have fewer sensory hairs, and are less differentiated. http://purl.obolibrary.org/obo/GO_0010817 regulation of hormone levels http://purl.obolibrary.org/obo/GO_0065008 regulation of biological quality Any process that modulates the levels of hormone within an organism or a tissue. A hormone is any substance formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells in the same organism, upon which it has a specific regulatory action. http://purl.obolibrary.org/obo/CL_0000590 small luteal cell http://purl.obolibrary.org/obo/CL_0000175 luteal cell A progesterone secreting cell in the corpus luteum that develops from theca cells. http://purl.obolibrary.org/obo/GO_0010927 cellular component assembly involved in morphogenesis http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The cellular component assembly that is part of the initial shaping of the component during its developmental progression. http://purl.obolibrary.org/obo/CL_0000591 warmth sensing thermoreceptor cell http://purl.obolibrary.org/obo/CL_0000205 thermoreceptor cell A thermoreceptor cell that detects increased temperatures. http://purl.obolibrary.org/obo/GO_0010954 positive regulation of protein processing http://purl.obolibrary.org/obo/GO_1903319 positive regulation of protein maturation Any process that increases the rate, frequency or extent of protein maturation by peptide bond cleavage. http://purl.obolibrary.org/obo/CL_0000592 large luteal cell http://purl.obolibrary.org/obo/CL_0000177 testosterone secreting cell A large, progesterone secreting cell in the corpus luteum that develops from the granulosa cells. http://purl.obolibrary.org/obo/GO_0010959 regulation of metal ion transport http://purl.obolibrary.org/obo/GO_0043269 regulation of monoatomic ion transport Any process that modulates the frequency, rate, or extent of metal ion transport. Metal ion transport is the directed movement of metal ions, any metal ion with an electric charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/CL_0000593 androgen secreting cell http://purl.obolibrary.org/obo/CL_0000174 steroid hormone secreting cell A steroid hormone secreting cell that secretes androgen. http://purl.obolibrary.org/obo/GO_0012501 programmed cell death http://purl.obolibrary.org/obo/GO_0008219 cell death A process which begins when a cell receives an internal or external signal and activates a series of biochemical events (signaling pathway). The process ends with the death of the cell. http://purl.obolibrary.org/obo/CL_0000594 skeletal muscle satellite cell http://purl.obolibrary.org/obo/CL_0000680 muscle precursor cell An elongated, spindle-shaped, cell that is located between the basal lamina and the plasmalemma of a muscle fiber. These cells are mostly quiescent, but upon activation they divide to produce cells that generate new muscle fibers. http://purl.obolibrary.org/obo/GO_0014020 primary neural tube formation http://purl.obolibrary.org/obo/GO_0001838 embryonic epithelial tube formation The formation of the neural tube from an epithelial cell sheet (the neuroepithelium or neural plate). In primary neurulation, the cells surrounding the neural plate direct the neural plate cells to proliferate, invaginate, and pinch off from the surface to form a hollow epithelial tube. Primary neurulation is the typical mechanism of formation of the anterior neural tube. http://purl.obolibrary.org/obo/CL_0000595 enucleate erythrocyte http://purl.obolibrary.org/obo/CL_0000232 erythrocyte An erythrocyte lacking a nucleus. http://purl.obolibrary.org/obo/GO_0014032 neural crest cell development http://purl.obolibrary.org/obo/GO_0048864 stem cell development The process aimed at the progression of a neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell. http://purl.obolibrary.org/obo/CL_0000596 sexual spore http://purl.obolibrary.org/obo/CL_0002369 fungal spore A spore formed following meiosis. Sometimes following meiosis, prospores may undergo one or more rounds of mitosis before they are fully mature. http://purl.obolibrary.org/obo/GO_0014075 response to amine http://purl.obolibrary.org/obo/GO_1901698 response to nitrogen compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amine stimulus. An amine is a compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups. http://purl.obolibrary.org/obo/CL_0000597 microconidium http://purl.obolibrary.org/obo/CL_0002381 uninucleate conidium The smaller of two types of asexual spores formed by some fungi. An ovoid to pear-shaped asexual spore that contains very little cytoplasm and organelles, is uninucleate, and forms in vegetative hypae within a mycelium. Micronidia are extruded from the hyphal cell wall. http://purl.obolibrary.org/obo/GO_0014706 striated muscle tissue development http://purl.obolibrary.org/obo/GO_0060537 muscle tissue development The process whose specific outcome is the progression of a striated muscle over time, from its formation to the mature structure. Striated muscle contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle. Skeletal muscle myoblasts fuse to form myotubes and eventually multinucleated muscle fibers. The fusion of cardiac cells is very rare and can only form binucleate cells. http://purl.obolibrary.org/obo/CL_0000598 pyramidal neuron http://purl.obolibrary.org/obo/CL_2000029 central nervous system neuron Pyramidal neurons have a pyramid-shaped soma with a single axon, a large apical dendrite and multiple basal dendrites. The apex and an apical dendrite typically point toward the pial surface and other dendrites and an axon emerging from the base. The axons may have local collaterals but also project outside their region. Pyramidal neurons are found in the cerebral cortex, the hippocampus, and the amygdala. http://purl.obolibrary.org/obo/GO_0014896 muscle hypertrophy http://purl.obolibrary.org/obo/GO_0003012 muscle system process The muscle system process that results in enlargement or overgrowth of all or part of a muscle organ due to an increase in the size of its muscle cells. Physiological hypertrophy is a normal process during development (it stops in cardiac muscle after adolescence) and can also be brought on in response to demand. In athletes cardiac and skeletal muscles undergo hypertrophy stimulated by increasing muscle activity on exercise. Smooth muscle cells in the uterus undergo hypertrophy during pregnancy. http://purl.obolibrary.org/obo/CL_0000599 conidium http://purl.obolibrary.org/obo/CL_0000605 fungal asexual spore An asexual, nonmotile spore formed by higher fungi; conidia are usually made from the side or tip of specialized sporogenous cells and do not form by progressive cleavage of the cytoplasm. http://purl.obolibrary.org/obo/GO_0014897 striated muscle hypertrophy http://purl.obolibrary.org/obo/GO_0014896 muscle hypertrophy The enlargement or overgrowth of all or part of an organ due to an increase in size of muscle cells without cell division. In the case of striated muscle, this happens due to the additional synthesis of sarcomeric proteins and assembly of myofibrils. http://purl.obolibrary.org/obo/CL_0000600 heterokaryon http://purl.obolibrary.org/obo/CL_0000521 fungal cell A fungal cell with two or more genetically distinct nuclei. http://purl.obolibrary.org/obo/GO_0015078 proton transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0008324 monoatomic cation transmembrane transporter activity Enables the transfer of a proton from one side of a membrane to the other. http://purl.obolibrary.org/obo/CL_0000601 cochlear outer hair cell http://purl.obolibrary.org/obo/CL_4023120 cochlea auditory hair cell A mechanoreceptor in the organ of Corti. In mammals the outer hair cells are arranged in three rows which are further from the modiolus than the single row of inner hair cells. The motile properties of the outer hair cells may contribute actively to tuning the sensitivity and frequency selectivity of the cochlea. http://purl.obolibrary.org/obo/GO_0015171 amino acid transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity Enables the transfer of amino acids from one side of a membrane to the other. Amino acids are organic molecules that contain an amino group and a carboxyl group. http://purl.obolibrary.org/obo/CL_0000602 pressoreceptor cell http://purl.obolibrary.org/obo/CL_1000082 stretch receptor cell A receptor in the vascular system, particularly the aorta and carotid sinus, which is sensitive to stretch of the vessel walls. http://purl.obolibrary.org/obo/GO_0015175 neutral L-amino acid transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0015171 amino acid transmembrane transporter activity Enables the transfer of neutral L-amino acids from one side of a membrane to the other. Neutral amino acids have side chains with no charge at pH 7.3. http://purl.obolibrary.org/obo/CL_0000603 dikaryon http://purl.obolibrary.org/obo/CL_0000600 heterokaryon A fungal cell with two genetically distinct haploid nuclei. http://purl.obolibrary.org/obo/GO_0015179 L-amino acid transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0015171 amino acid transmembrane transporter activity Enables the transfer of an L-amino acid from one side of a membrane to the other. L-amino acids are the L-enantiomers of amino acids. http://purl.obolibrary.org/obo/CL_0000604 retinal rod cell http://purl.obolibrary.org/obo/CL_0010009 camera-type eye photoreceptor cell One of the two photoreceptor cell types of the vertebrate retina. In rods the photopigment is in stacks of membranous disks separate from the outer cell membrane. Rods are more sensitive to light than cones, but rod mediated vision has less spatial and temporal resolution than cone vision. http://purl.obolibrary.org/obo/GO_0015216 purine nucleotide transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0015215 nucleotide transmembrane transporter activity Enables the transfer of a purine nucleotide, any compound consisting of a purine nucleoside esterified with (ortho)phosphate, from one side of a membrane to the other. http://purl.obolibrary.org/obo/CL_0000605 fungal asexual spore http://purl.obolibrary.org/obo/CL_0002369 fungal spore A spore formed following mitosis or mitoses. http://purl.obolibrary.org/obo/GO_0015291 secondary active transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022804 active transmembrane transporter activity Enables the transfer of a solute from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy, not direct ATP coupling. Secondary active transporters include symporters and antiporters. http://purl.obolibrary.org/obo/CL_0000606 macroconidium http://purl.obolibrary.org/obo/CL_0000599 conidium The larger of two types of asexual spores formed by some fungi; usually round or oblong. http://purl.obolibrary.org/obo/GO_0015464 acetylcholine receptor activity http://purl.obolibrary.org/obo/GO_0098960 postsynaptic neurotransmitter receptor activity Combining with an acetylcholine receptor ligand and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. http://purl.obolibrary.org/obo/CL_0000607 ascospore http://purl.obolibrary.org/obo/CL_0000596 sexual spore A thick walled spore that stores and protects one or more nuclei following sexual reproduction in an Ascomycete. http://purl.obolibrary.org/obo/GO_0015605 organophosphate ester transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity Enables the transfer of organophosphate esters from one side of a membrane to the other. Organophosphate esters are small organic molecules containing phosphate ester bonds. http://purl.obolibrary.org/obo/CL_0000608 zygospore http://purl.obolibrary.org/obo/CL_0000596 sexual spore A thick walled, sexual, resting spore formed by Zygomycetes; sometimes refers to the spore and the multi-layered cell wall that encloses the spore, the zygosporangium. http://purl.obolibrary.org/obo/GO_0015629 actin cytoskeleton http://purl.obolibrary.org/obo/GO_0005856 cytoskeleton The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes. http://purl.obolibrary.org/obo/CL_0000609 vestibular hair cell http://purl.obolibrary.org/obo/CL_0002374 ear hair cell A mechanoreceptor located in the acoustic maculae and the semicircular canals that mediates the sense of balance, movement, and head position. The vestibular hair cells are connected to accessory structures in such a way that movements of the head displace their stereocilia. This influences the membrane potential of the cells which relay information about movements via the vestibular part of the vestibulocochlear nerve to the brain stem. http://purl.obolibrary.org/obo/GO_0015630 microtubule cytoskeleton http://purl.obolibrary.org/obo/GO_0005856 cytoskeleton The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins. http://purl.obolibrary.org/obo/CL_0000611 eosinophil progenitor cell http://purl.obolibrary.org/obo/CL_0002191 granulocytopoietic cell Any granulocytopoietic cell that has part some transcription factor PU.1 and has part some CCAAT/enhancer-binding protein alpha and has part some erythroid transcription factor and lacks plasma membrane part some CD19 molecule and lacks plasma membrane part some CD4 molecule and lacks plasma membrane part some integrin alpha-M and lacks plasma membrane part some CD3 epsilon and lacks plasma membrane part some neural cell adhesion molecule 1 and lacks plasma membrane part some CD2 molecule and lacks plasma membrane part some T-cell surface glycoprotein CD8 alpha chain and lacks plasma membrane part some membrane-spanning 4-domains subfamily A member 1 and lacks plasma membrane part some T-cell surface glycoprotein CD5 and lacks plasma membrane part some CD14 molecule and lacks plasma membrane part some lymphocyte antigen 6G and lacks plasma membrane part some lymphocyte antigen 76 (mouse) and has plasma membrane part some CD34 molecule and has plasma membrane part some ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 and has plasma membrane part some interleukin-3 receptor class 2 alpha chain and has plasma membrane part some interleukin-5 receptor subunit alpha and has plasma membrane part some mast/stem cell growth factor receptor and is capable of some eosinophil differentiation. http://purl.obolibrary.org/obo/GO_0015698 inorganic anion transport http://purl.obolibrary.org/obo/GO_0006810 transport The directed movement of inorganic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Inorganic anions are atoms or small molecules with a negative charge which do not contain carbon in covalent linkage. http://purl.obolibrary.org/obo/CL_0000612 eosinophilic myelocyte http://purl.obolibrary.org/obo/CL_0002193 myelocyte A eosinophil precursor in the granulocytic series, being a cell intermediate in development between a promyelocyte and a metamyelocyte;in this stage, production of primary granules is complete and eosinophil-specific granules has started. No nucleolus is present. These cells are integrin alpha-M-positive, CD13-positive, CD15-positive, CD16-negative, CD24-positive, and CD33-positive. http://purl.obolibrary.org/obo/GO_0015711 organic anion transport http://purl.obolibrary.org/obo/GO_0006810 transport The directed movement of organic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage. http://purl.obolibrary.org/obo/CL_0000613 basophil progenitor cell http://purl.obolibrary.org/obo/CL_0002191 granulocytopoietic cell A progenitor cell committed to the basophil lineage. This cell lacks hematopoietic lineage markers (lin-negative) and is CD34-positive, T1/ST2-low, CD117-negative, and FceRIa-high. This cell also expresses Gata-1, Gata-2 and C/EBPa. http://purl.obolibrary.org/obo/GO_0015748 organophosphate ester transport http://purl.obolibrary.org/obo/GO_0006810 transport The directed movement of organophosphate esters into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organophosphate esters are small organic molecules containing phosphate ester bonds. http://purl.obolibrary.org/obo/CL_0000614 basophilic myelocyte http://purl.obolibrary.org/obo/CL_0002087 nongranular leukocyte A basophil precursor in the granulocytic series, being a cell intermediate in development between a promyelocyte and a metamyelocyte; in this stage, production of primary granules is complete and basophil-specific granules has started. No nucleolus is present. Markers are being integrin alpha-M-positive, fucosyltransferase FUT4-positive, CD33-positive, CD24-positive, aminopeptidase N-positive. http://purl.obolibrary.org/obo/GO_0015804 neutral amino acid transport http://purl.obolibrary.org/obo/GO_0006865 amino acid transport The directed movement of neutral amino acids, amino acids with no net charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/CL_0000615 basidiospore http://purl.obolibrary.org/obo/CL_0000596 sexual spore A thick walled spore containing one or more haploid nuclei produced by sexual reproduction in an Basidiomycete; formed externally on extrusions of the basidium. http://purl.obolibrary.org/obo/GO_0015813 L-glutamate transmembrane transport http://purl.obolibrary.org/obo/GO_0051938 L-glutamate import The directed movement of L-glutamate across a membrane by means of some agent such as a transporter or a pore. http://purl.obolibrary.org/obo/CL_0000617 GABAergic neuron http://purl.obolibrary.org/obo/CL_0000540 neuron A neuron that uses GABA as a vesicular neurotransmitter http://purl.obolibrary.org/obo/GO_0015833 peptide transport http://purl.obolibrary.org/obo/GO_0006810 transport The directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/CL_0000621 fusion competent myoblast http://purl.obolibrary.org/obo/CL_0008018 somatic muscle myoblast A myoblast that is committed to a myotube-specific program of differentiation but not yet fused. It undergoes very limited additional proliferation. After fusion, it will take on a muscle identity specified by a `muscle founder cell` (CL:0008006). http://purl.obolibrary.org/obo/GO_0015865 purine nucleotide transport http://purl.obolibrary.org/obo/GO_0006862 nucleotide transport The directed movement of a purine nucleotide, any compound consisting of a purine nucleoside esterified with (ortho)phosphate, into, out of or within a cell. http://purl.obolibrary.org/obo/CL_0000622 acinar cell http://purl.obolibrary.org/obo/CL_0000154 protein secreting cell A secretory cell that is grouped together with other cells of the same type to form grape shaped clusters known as acini (singular acinus). http://purl.obolibrary.org/obo/GO_0015908 fatty acid transport http://purl.obolibrary.org/obo/GO_0006869 lipid transport The directed movement of fatty acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Fatty acids are aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis. http://purl.obolibrary.org/obo/CL_0000623 natural killer cell http://purl.obolibrary.org/obo/CL_0001067 group 1 innate lymphoid cell A lymphocyte that can spontaneously kill a variety of target cells without prior antigenic activation via germline encoded activation receptors and also regulate immune responses via cytokine release and direct contact with other cells. http://purl.obolibrary.org/obo/GO_0016049 cell growth http://purl.obolibrary.org/obo/GO_0040007 growth The process in which a cell irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present. http://purl.obolibrary.org/obo/CL_0000624 CD4-positive, alpha-beta T cell http://purl.obolibrary.org/obo/CL_0000791 mature alpha-beta T cell A mature alpha-beta T cell that expresses an alpha-beta T cell receptor and the CD4 coreceptor. http://purl.obolibrary.org/obo/GO_0016050 vesicle organization http://purl.obolibrary.org/obo/GO_0006996 organelle organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vesicle. http://purl.obolibrary.org/obo/CL_0000625 CD8-positive, alpha-beta T cell http://purl.obolibrary.org/obo/CL_0000791 mature alpha-beta T cell A T cell expressing an alpha-beta T cell receptor and the CD8 coreceptor. http://purl.obolibrary.org/obo/GO_0016051 carbohydrate biosynthetic process http://purl.obolibrary.org/obo/GO_0009058 biosynthetic process The chemical reactions and pathways resulting in the formation of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. http://purl.obolibrary.org/obo/CL_0000626 olfactory granule cell http://purl.obolibrary.org/obo/CL_1001434 olfactory bulb interneuron A granule cell that has a soma located in an olfactory bulb granule cell layer. An olfactory granule cell is an interneuron that lacks an axon, makes reciprocal dendro-dendritic synapses with mitral cells and tufted cells and is involved in the fine spatio-temporal tuning of the responses of these principal olfactory bulb neurons to odors. http://purl.obolibrary.org/obo/GO_0016052 carbohydrate catabolic process http://purl.obolibrary.org/obo/GO_0009056 catabolic process The chemical reactions and pathways resulting in the breakdown of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. http://purl.obolibrary.org/obo/CL_0000628 photosynthetic cell http://purl.obolibrary.org/obo/CL_0000000 cell A cell that can perform photosynthesis, in which carbohydrates are synthesized from carbon dioxide and water, using light as the energy source. http://purl.obolibrary.org/obo/GO_0016064 immunoglobulin mediated immune response http://purl.obolibrary.org/obo/GO_0019724 B cell mediated immunity An immune response mediated by immunoglobulins, whether cell-bound or in solution. http://purl.obolibrary.org/obo/CL_0000629 storage cell http://purl.obolibrary.org/obo/CL_0000325 stuff accumulating cell A cell that is specialized to store a particular substance(s), which is(are) later released from the store for a particular purpose. http://purl.obolibrary.org/obo/GO_0016070 RNA metabolic process http://purl.obolibrary.org/obo/GO_0090304 nucleic acid metabolic process The cellular chemical reactions and pathways involving RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. http://purl.obolibrary.org/obo/CL_0000630 supporting cell http://purl.obolibrary.org/obo/CL_0000000 cell A cell whose primary function is to support other cell types. http://purl.obolibrary.org/obo/GO_0016331 morphogenesis of embryonic epithelium http://purl.obolibrary.org/obo/GO_0048598 embryonic morphogenesis The process in which the anatomical structures of embryonic epithelia are generated and organized. http://purl.obolibrary.org/obo/CL_0000631 labyrinth supporting cell http://purl.obolibrary.org/obo/CL_0000630 supporting cell Cells forming a framework supporting the organ of Corti. Specific cells are those of Claudius, Deiters and Hensen. http://purl.obolibrary.org/obo/GO_0016358 dendrite development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the dendrite over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/CL_0000632 hepatic stellate cell http://purl.obolibrary.org/obo/CL_0000327 extracellular matrix secreting cell A cell that is found in the perisinusoidal space of the liver that is capable of multiple roles including storage of retinol, presentation of antigen to T cells (including CD1d-restricted NKT cells), and upon activation, production of extracellular matrix components that can contribute to liver fibrosis. This activated state has a myofibroblast-like phenotype, though it's not clear in the literature if this is terminally differentiated. This cell type comprises approximately 8-15% of total cells in the liver. http://purl.obolibrary.org/obo/GO_0016444 somatic cell DNA recombination http://purl.obolibrary.org/obo/GO_0006310 DNA recombination Recombination occurring within or between DNA molecules in somatic cells. http://purl.obolibrary.org/obo/CL_0000633 Hensen cell http://purl.obolibrary.org/obo/CL_0002490 organ of Corti supporting cell A tall supporting cell that is arranged in rows adjacent to the last row of outer phalangeal cells. This cell type constitutes the outer border of the organ of Corti. http://purl.obolibrary.org/obo/GO_0016445 somatic diversification of immunoglobulins http://purl.obolibrary.org/obo/GO_0002200 somatic diversification of immune receptors The somatic process that results in the generation of sequence diversity of immunoglobulins. http://purl.obolibrary.org/obo/CL_0000634 Claudius cell http://purl.obolibrary.org/obo/CL_0020029 cuboidal epithelial cell A cuboidal cell which along with Boettcher's cells form the floor of the external spiral sulcus, external to the organ of Corti. http://purl.obolibrary.org/obo/GO_0016446 somatic hypermutation of immunoglobulin genes http://purl.obolibrary.org/obo/GO_0016445 somatic diversification of immunoglobulins Mutations occurring somatically that result in amino acid changes in the rearranged V regions of immunoglobulins. http://purl.obolibrary.org/obo/CL_0000635 Deiter's cell http://purl.obolibrary.org/obo/CL_0002165 phalangeal cell The outer phalangeal cells of the organ of Corti. This cell holds the base of the hair cell in a cup-shaped depression. http://purl.obolibrary.org/obo/GO_0016447 somatic recombination of immunoglobulin gene segments http://purl.obolibrary.org/obo/GO_0016445 somatic diversification of immunoglobulins The process in which immunoglobulin genes are formed through recombination of the germline genetic elements, as known as immunoglobulin gene segments, within a single locus. http://purl.obolibrary.org/obo/CL_0000636 Mueller cell http://purl.obolibrary.org/obo/CL_0009004 retinal cell Astrocyte-like radial glial cell that extends vertically throughout the retina, with the nucleus are usually in the middle of the inner nuclear layer. http://purl.obolibrary.org/obo/GO_0016462 pyrophosphatase activity http://purl.obolibrary.org/obo/GO_0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides Catalysis of the hydrolysis of a pyrophosphate bond (diphosphate bond) between two phosphate groups. http://purl.obolibrary.org/obo/CL_0000637 chromophil cell of anterior pituitary gland http://purl.obolibrary.org/obo/CL_2000004 pituitary gland cell A cell that stains readily in the anterior pituitary gland. http://purl.obolibrary.org/obo/GO_0016477 cell migration http://purl.obolibrary.org/obo/GO_0048870 cell motility The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues. http://purl.obolibrary.org/obo/CL_0000638 acidophil cell of pars distalis of adenohypophysis http://purl.obolibrary.org/obo/CL_0000637 chromophil cell of anterior pituitary gland An acidophilic chromophil cell that of the anterior pituitary gland. http://purl.obolibrary.org/obo/GO_0016485 protein processing http://purl.obolibrary.org/obo/GO_0006508 proteolysis Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein. Protein maturation is the process leading to the attainment of the full functional capacity of a protein. http://purl.obolibrary.org/obo/CL_0000639 basophil cell of pars distalis of adenohypophysis http://purl.obolibrary.org/obo/CL_0000637 chromophil cell of anterior pituitary gland A basophilic chromophil cell that of the anterior pituitary gland. http://purl.obolibrary.org/obo/GO_0016486 peptide hormone processing http://purl.obolibrary.org/obo/GO_0140448 signaling receptor ligand precursor processing The generation of a mature peptide hormone by posttranslational processing of a prohormone. http://purl.obolibrary.org/obo/CL_0000641 chromophobe cell http://purl.obolibrary.org/obo/CL_0000163 endocrine cell A cell that is resistant to stains. http://purl.obolibrary.org/obo/GO_0016502 nucleotide receptor activity http://purl.obolibrary.org/obo/GO_0004888 transmembrane signaling receptor activity Combining with a nucleotide and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. A nucleotide is a compound that consists of a nucleoside esterified with a phosphate molecule. http://purl.obolibrary.org/obo/CL_0000642 folliculostellate cell http://purl.obolibrary.org/obo/CL_2000004 pituitary gland cell An agranular supporting cell of the anterior pituitary (adenohypophysis) that is characterized by a star-like morphology and ability to form follicles. Folliculostellate cells communicate with each other and with endocrine cells via gap junctions. http://purl.obolibrary.org/obo/GO_0016740 transferase activity http://purl.obolibrary.org/obo/GO_0003824 catalytic activity Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2. http://purl.obolibrary.org/obo/CL_0000644 Bergmann glial cell http://purl.obolibrary.org/obo/CL_0002603 astrocyte of the cerebellum Type of radial astrocyte in the cerebellar cortex that have their cell bodies in the Purkinje cell layer and processes that extend into the molecular layer, terminating with bulbous endfeet at the pial surface. Bergmann glia express high densities of glutamate transporters that limit diffusion of the neurotransmitter glutamate during its release from synaptic terminals. Besides their role in early development of the cerebellum, Bergmann glia are also required for the pruning or addition of synapses. http://purl.obolibrary.org/obo/GO_0016755 aminoacyltransferase activity http://purl.obolibrary.org/obo/GO_0016746 acyltransferase activity Catalysis of the transfer of an amino-acyl group from one compound (donor) to another (acceptor). http://purl.obolibrary.org/obo/CL_0000645 pituicyte http://purl.obolibrary.org/obo/CL_2000004 pituitary gland cell A glial cell of astrocytic lineage with long processes running parallel to adjacent axons in the proximal infundibulum of the neurohypophysis. These processes form a three-dimensional network among the axons of the hypothalamic neurosecretory cells and are connected by gap junctions which provide for their metabolic coupling. This cell type constitutes most of the nonexcitable tissue in the neurohypophsis; function may include possibly acting as an intermediate in the modulation of oxytocin and vasopressin release. This cell type is highly variable in size and shape and commonly contain lipid droplets and deposits of lipochrome pigment. http://purl.obolibrary.org/obo/GO_0016787 hydrolase activity http://purl.obolibrary.org/obo/GO_0003824 catalytic activity Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. http://purl.obolibrary.org/obo/CL_0000646 basal cell http://purl.obolibrary.org/obo/CL_0000036 epithelial fate stem cell Undifferentiated; mitotic stem cell for other epithelial cell types; rounded or elliptical with little cytoplasm and few organelles; contain cytokeratin intermediate filament. http://purl.obolibrary.org/obo/GO_0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides http://purl.obolibrary.org/obo/GO_0016817 hydrolase activity, acting on acid anhydrides Catalysis of the hydrolysis of any acid anhydride which contains phosphorus. http://purl.obolibrary.org/obo/CL_0000647 multinucleated giant cell http://purl.obolibrary.org/obo/CL_0000766 myeloid leukocyte A phagocytic syncytial cell formed by the fusion of macrophages, occurs in chronic inflammatory responses to persistent microorganism such as M.tuberculosis, component of granulomas. Sometimes used to refer to megakaryocytes. http://purl.obolibrary.org/obo/GO_0016853 isomerase activity http://purl.obolibrary.org/obo/GO_0003824 catalytic activity Catalysis of the geometric or structural changes within one molecule. Isomerase is the systematic name for any enzyme of EC class 5. http://purl.obolibrary.org/obo/CL_0000648 kidney granular cell http://purl.obolibrary.org/obo/CL_1000618 juxtaglomerular complex cell A smooth muscle cell that synthesizes, stores, and secretes the enzyme renin. This cell type are located in the wall of the afferent arteriole at the entrance to the glomerulus. While having a different origin than other kidney smooth muscle cells, this cell type expresses smooth muscle actin upon maturation. http://purl.obolibrary.org/obo/GO_0016887 ATP hydrolysis activity http://purl.obolibrary.org/obo/GO_0017111 ribonucleoside triphosphate phosphatase activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient. http://purl.obolibrary.org/obo/CL_0000649 spinous cell of epidermis http://purl.obolibrary.org/obo/CL_4052061 epidermal keratinocyte A keratinocyte found within the stratum spinosum (prickle cell layer) of the epidermis, distinguished by numerous intercellular desmosomes, which give it a “prickly” or spiny appearance. Positioned above the mitotically active basal layer and beneath the granular layer, it contributes to the skin’s mechanical strength and barrier function, preventing water loss and pathogen entry. This cell expresses differentiation-specific keratins K1 and K10 in mice, unlike basal cells that express K5 and K14, and lacks the keratohyalin granules found in granular cells, marking its intermediate stage of epidermal differentiation. http://purl.obolibrary.org/obo/GO_0017076 purine nucleotide binding http://purl.obolibrary.org/obo/GO_0000166 nucleotide binding Binding to a purine nucleotide, a compound consisting of a purine nucleoside esterified with (ortho)phosphate. http://purl.obolibrary.org/obo/CL_0000650 mesangial cell http://purl.obolibrary.org/obo/CL_1001318 renal interstitial pericyte A cell type that encapsulates the capillaries and venules in the kidney. This cell secretes mesangial matrix that provides the structural support for the capillaries. http://purl.obolibrary.org/obo/GO_0017111 ribonucleoside triphosphate phosphatase activity http://purl.obolibrary.org/obo/GO_0016462 pyrophosphatase activity Catalysis of the reaction: a ribonucleoside triphosphate + H2O = a ribonucleoside diphosphate + H+ + phosphate. http://purl.obolibrary.org/obo/CL_0000652 pinealocyte http://purl.obolibrary.org/obo/CL_0002319 neural cell This cell type produces and secretes melatonin and forms the pineal parenchyma. Extending from each cell body, which has a spherical, oval or lobulated mucleus, are one or more tortuous basophilic processes, containing parallel microtubules known as synaptic ribbons. These processes end in expanded terminal buds near capillaries or less, frequently, ependymal cells of the pineal recess. The terminal buds contain granular endoplasmic reticulum, mitochondria and electron-dense cored vesicles, which store monoamines and polypeptide hormones, release of which appears to require sympathetic innervation. http://purl.obolibrary.org/obo/GO_0017157 regulation of exocytosis http://purl.obolibrary.org/obo/GO_0060627 regulation of vesicle-mediated transport Any process that modulates the frequency, rate or extent of exocytosis. http://purl.obolibrary.org/obo/CL_0000653 podocyte http://purl.obolibrary.org/obo/CL_1000450 epithelial cell of glomerular capsule A specialized kidney epithelial cell, contained within a glomerulus, that contains "feet" that interdigitate with the "feet" of other podocytes. http://purl.obolibrary.org/obo/GO_0019221 cytokine-mediated signaling pathway http://purl.obolibrary.org/obo/GO_0007166 cell surface receptor signaling pathway The series of molecular signals initiated by the binding of a cytokine to a receptor on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription. http://purl.obolibrary.org/obo/CL_0000654 primary oocyte http://purl.obolibrary.org/obo/CL_0000023 oocyte A primary oocyte is an oocyte that has not completed female meosis I. http://purl.obolibrary.org/obo/GO_0019236 response to pheromone http://purl.obolibrary.org/obo/GO_0042221 response to chemical Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pheromone stimulus. http://purl.obolibrary.org/obo/CL_0000655 secondary oocyte http://purl.obolibrary.org/obo/CL_0000023 oocyte A secondary oocyte is an oocyte that has not completed meiosis II. http://purl.obolibrary.org/obo/GO_0019724 B cell mediated immunity http://purl.obolibrary.org/obo/GO_0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains Any process involved with the carrying out of an immune response by a B cell, through, for instance, the production of antibodies or cytokines, or antigen presentation to T cells. http://purl.obolibrary.org/obo/CL_0000656 primary spermatocyte http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell A diploid cell that has derived from a spermatogonium and can subsequently begin meiosis and divide into two haploid secondary spermatocytes. http://purl.obolibrary.org/obo/GO_0019730 antimicrobial humoral response http://purl.obolibrary.org/obo/GO_0140546 defense response to symbiont An immune response against microbes mediated through a body fluid. Examples of this process are seen in the antimicrobial humoral response of Drosophila melanogaster and Mus musculus. http://purl.obolibrary.org/obo/CL_0000657 secondary spermatocyte http://purl.obolibrary.org/obo/CL_0000413 haploid cell One of the two haploid cells into which a primary spermatocyte divides, and which in turn gives origin to spermatids. http://purl.obolibrary.org/obo/GO_0019865 immunoglobulin binding http://purl.obolibrary.org/obo/GO_0044877 protein-containing complex binding Binding to an immunoglobulin. http://purl.obolibrary.org/obo/CL_0000658 cuticle secreting cell http://purl.obolibrary.org/obo/CL_0000327 extracellular matrix secreting cell An epithelial cell that secretes cuticle. http://purl.obolibrary.org/obo/GO_0019882 antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002376 immune system process The process in which an antigen-presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex. http://purl.obolibrary.org/obo/CL_0000659 eggshell secreting cell http://purl.obolibrary.org/obo/CL_0000500 follicular epithelial cell An extracellular matrix secreting cell that secretes eggshell. http://purl.obolibrary.org/obo/GO_0019883 antigen processing and presentation of endogenous antigen http://purl.obolibrary.org/obo/GO_0019882 antigen processing and presentation The process in which an antigen-presenting cell expresses antigen (peptide or lipid) of endogenous origin on its cell surface in association with an MHC protein complex. http://purl.obolibrary.org/obo/CL_0000660 glycocalyx secreting cell http://purl.obolibrary.org/obo/CL_0000327 extracellular matrix secreting cell An extracellular matrix secreting cell that secretes glycocalyx. http://purl.obolibrary.org/obo/GO_0019884 antigen processing and presentation of exogenous antigen http://purl.obolibrary.org/obo/GO_0019882 antigen processing and presentation The process in which an antigen-presenting cell expresses antigen (peptide or lipid) of exogenous origin on its cell surface in association with an MHC protein complex. http://purl.obolibrary.org/obo/CL_0000666 fenestrated endothelial cell http://purl.obolibrary.org/obo/CL_0000115 endothelial cell An endothelial cell that has small pores, or fenestrations, which allow for the efficient exchange of substances between the blood and surrounding tissues. http://purl.obolibrary.org/obo/GO_0019953 sexual reproduction http://purl.obolibrary.org/obo/GO_0022414 reproductive process A type of reproduction that combines the genetic material of two gametes (such as a sperm or egg cell or fungal spores). The gametes have an haploid genome (with a single set of chromosomes, the product of a meiotic division) and combines with one another to produce a zygote (diploid). http://purl.obolibrary.org/obo/CL_0000667 collagen secreting cell http://purl.obolibrary.org/obo/CL_0000327 extracellular matrix secreting cell An extracellular matrix secreting cell that secretes collagen. http://purl.obolibrary.org/obo/GO_0019955 cytokine binding http://purl.obolibrary.org/obo/GO_0005515 protein binding Binding to a cytokine, any of a group of proteins that function to control the survival, growth and differentiation of tissues and cells, and which have autocrine and paracrine activity. http://purl.obolibrary.org/obo/CL_0000669 pericyte http://purl.obolibrary.org/obo/CL_0008034 mural cell An elongated, contractile cell found wrapped about precapillary arterioles outside the basement membrane. Pericytes are present in capillaries where proper adventitia and muscle layer are missing (thus distingushing this cell type from adventitial cells). They are relatively undifferentiated and may become fibroblasts, macrophages, or smooth muscle cells. http://purl.obolibrary.org/obo/GO_0021915 neural tube development http://purl.obolibrary.org/obo/GO_0060429 epithelium development The process whose specific outcome is the progression of the neural tube over time, from its formation to the mature structure. The mature structure of the neural tube exists when the tube has been segmented into the forebrain, midbrain, hindbrain and spinal cord regions. In addition neural crest has budded away from the epithelium. http://purl.obolibrary.org/obo/CL_0000670 primordial germ cell http://purl.obolibrary.org/obo/CL_0000219 motile cell A primordial germ cell is a diploid germ cell precursors that transiently exist in the embryo before they enter into close association with the somatic cells of the gonad and become irreversibly committed as germ cells. http://purl.obolibrary.org/obo/GO_0022402 cell cycle process http://purl.obolibrary.org/obo/GO_0009987 cellular process The cellular process that ensures successive accurate and complete genome replication and chromosome segregation. http://purl.obolibrary.org/obo/CL_0000671 centripetally migrating follicle cell http://purl.obolibrary.org/obo/CL_0000477 follicle cell of egg chamber A follicle cell that migrates from the dorso-anterior part of the oocyte associated follicular epithelium, in between the nurse cells and the oocyte, and participates in the formation of the operculum. http://purl.obolibrary.org/obo/GO_0022403 cell cycle phase http://purl.obolibrary.org/obo/GO_0044848 biological phase One of the distinct periods or stages into which the cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events. http://purl.obolibrary.org/obo/CL_0000673 Kenyon cell http://purl.obolibrary.org/obo/CL_0000028 CNS neuron (sensu Nematoda and Protostomia) An intrinsic neuron of the mushroom body of arthropods and annelids. They have tightly packed, cytoplasm-poor cell bodies. http://purl.obolibrary.org/obo/GO_0022405 hair cycle process http://purl.obolibrary.org/obo/GO_0022404 molting cycle process A multicellular organismal process involved in the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair; one of the collection or mass of filaments growing from the skin of an animal, and forming a covering for a part of the head or for any part or the whole of the body. http://purl.obolibrary.org/obo/CL_0000674 interfollicle cell http://purl.obolibrary.org/obo/CL_0000477 follicle cell of egg chamber A follicle cell that is part of the stalk connecting adjacent egg chambers. http://purl.obolibrary.org/obo/GO_0022412 cellular process involved in reproduction in multicellular organism http://purl.obolibrary.org/obo/GO_0009987 cellular process A process, occurring at the cellular level, that is involved in the reproductive function of a multicellular organism. http://purl.obolibrary.org/obo/CL_0000675 female gamete http://purl.obolibrary.org/obo/CL_0000300 gamete A mature sexual reproductive cell of the female germline. http://purl.obolibrary.org/obo/GO_0022413 reproductive process in single-celled organism http://purl.obolibrary.org/obo/GO_0022414 reproductive process A process, occurring at the cellular level, that is involved in the reproductive function of a single-celled organism. http://purl.obolibrary.org/obo/CL_0000677 gut absorptive cell http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell Cell of the intestinal epithelium with a brush border made up of many parallel packed microvilli; associated with absorption, particularly of macromolecules. http://purl.obolibrary.org/obo/GO_0022414 reproductive process http://purl.obolibrary.org/obo/GO_0008150 biological_process A biological process that directly contributes to the process of producing new individuals by one or two organisms. The new individuals inherit some proportion of their genetic material from the parent or parents. http://purl.obolibrary.org/obo/CL_0000678 commissural neuron http://purl.obolibrary.org/obo/CL_2000029 central nervous system neuron A neuron with soma location in the central nervous system that project its axon to the contralateral side of a central nervous system. This neuron can have its soma in the spinal cord, in the hemisphere of the brain, in the retina or in the ventral nerve cord of invertebrates. http://purl.obolibrary.org/obo/GO_0022600 digestive system process http://purl.obolibrary.org/obo/GO_0003008 system process A physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism. http://purl.obolibrary.org/obo/GO_0022602 ovulation cycle process http://purl.obolibrary.org/obo/GO_0022414 reproductive process A process involved in the sexual cycle seen in females, often with physiologic changes in the endometrium that recur at regular intervals during the reproductive years. http://purl.obolibrary.org/obo/CL_0000679 glutamatergic neuron http://purl.obolibrary.org/obo/CL_0000540 neuron A neuron that is capable of some neurotansmission by glutamate secretion. http://purl.obolibrary.org/obo/GO_0022603 regulation of anatomical structure morphogenesis http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of anatomical structure morphogenesis. http://purl.obolibrary.org/obo/CL_0000680 muscle precursor cell http://purl.obolibrary.org/obo/CL_0011026 progenitor cell A non-terminally differentiated cell that is capable of developing into a muscle cell. http://purl.obolibrary.org/obo/GO_0022607 cellular component assembly http://purl.obolibrary.org/obo/GO_0016043 cellular component organization The aggregation, arrangement and bonding together of a cellular component. http://purl.obolibrary.org/obo/CL_0000681 radial glial cell http://purl.obolibrary.org/obo/CL_0000125 glial cell A cell present in the developing CNS. Functions as both a precursor cell and as a scaffold to support neuronal migration. http://purl.obolibrary.org/obo/GO_0022618 protein-RNA complex assembly http://purl.obolibrary.org/obo/GO_0071826 protein-RNA complex organization The aggregation, arrangement and bonding together of proteins and RNA molecules to form a ribonucleoprotein complex. http://purl.obolibrary.org/obo/GO_0023051 regulation of signaling http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process Any process that modulates the frequency, rate or extent of a signaling process. http://purl.obolibrary.org/obo/CL_0000682 M cell of gut http://purl.obolibrary.org/obo/CL_0002563 intestinal epithelial cell An absorptive cell of the gut epithelium that endocytoses microorganisms and intact macromolecules from the gut lumen and transports them to the subepithelial space where they are presented to antigen-presenting cells and lymphocytes. http://purl.obolibrary.org/obo/GO_0023056 positive regulation of signaling http://purl.obolibrary.org/obo/GO_0048518 positive regulation of biological process Any process that activates, maintains or increases the frequency, rate or extent of a signaling process. http://purl.obolibrary.org/obo/CL_0000683 ependymoglial cell http://purl.obolibrary.org/obo/CL_0000065 ependymal cell A cell that transports hormones from neurosecretory cells. This nerve cell is characterized by bipolar shape and endfeet that contact a basal lamina around blood vessels, and/or the pia mater or vitreous body of the eye and additionally contact the ventricular surface or sub-retinal space. http://purl.obolibrary.org/obo/GO_0023057 negative regulation of signaling http://purl.obolibrary.org/obo/GO_0048519 negative regulation of biological process Any process that stops, prevents, or reduces the frequency, rate or extent of a signaling process. http://purl.obolibrary.org/obo/CL_0000686 cerebrospinal fluid secreting cell http://purl.obolibrary.org/obo/CL_0000710 neurecto-epithelial cell A columnar/cuboidal epithelial cell that secretes cerebrospinal fluid. http://purl.obolibrary.org/obo/GO_0030001 metal ion transport http://purl.obolibrary.org/obo/GO_0006812 monoatomic cation transport The directed movement of metal ions, any metal ion with an electric charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/CL_0000688 perijunctional fibroblast http://purl.obolibrary.org/obo/CL_0000630 supporting cell A fibroblast-like cell that provides support at neuromuscular junctions in vertebrates and are localized outside the synaptic basal lamina. http://purl.obolibrary.org/obo/GO_0030010 establishment of cell polarity http://purl.obolibrary.org/obo/GO_0007163 establishment or maintenance of cell polarity The specification and formation of anisotropic intracellular organization or cell growth patterns. http://purl.obolibrary.org/obo/CL_0000689 myoendocrine cell http://purl.obolibrary.org/obo/CL_0000163 endocrine cell A cell with both myofibrils and secretory granules. http://purl.obolibrary.org/obo/GO_0030097 hemopoiesis http://purl.obolibrary.org/obo/GO_0048468 cell development The process whose specific outcome is the progression of the myeloid and lymphoid derived organ/tissue systems of the blood and other parts of the body over time, from formation to the mature structure. The site of hemopoiesis is variable during development, but occurs primarily in bone marrow or kidney in many adult vertebrates. http://purl.obolibrary.org/obo/CL_0000691 stellate interneuron http://purl.obolibrary.org/obo/CL_0000122 stellate neuron Any interneuron that has characteristic some stellate morphology. http://purl.obolibrary.org/obo/GO_0030098 lymphocyte differentiation http://purl.obolibrary.org/obo/GO_1903131 mononuclear cell differentiation The process in which a relatively unspecialized precursor cell acquires specialized features of a lymphocyte. A lymphocyte is a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin. http://purl.obolibrary.org/obo/CL_0000692 terminal Schwann cell http://purl.obolibrary.org/obo/CL_0002376 non-myelinating Schwann cell A neuroglial cell of the peripheral nervous system inside the basal lamina of the neuromuscular junction providing chemical and physical support to the synapse. http://purl.obolibrary.org/obo/GO_0030099 myeloid cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte, megakaryocyte, thrombocyte, or erythrocyte lineages. http://purl.obolibrary.org/obo/CL_0000693 neurogliaform cell http://purl.obolibrary.org/obo/CL_0000099 interneuron An interneuron that has spider-like appearance with a small round soma, a large number (7-10) of short, smooth, or slightly beaded primary dendrites that give rise to only a few secondary branches, and a branched axon that establishes a dense axonal mesh with thin shafts. http://purl.obolibrary.org/obo/GO_0030101 natural killer cell activation http://purl.obolibrary.org/obo/GO_0046649 lymphocyte activation The change in morphology and behavior of a natural killer cell in response to a cytokine, chemokine, cellular ligand, or soluble factor. http://purl.obolibrary.org/obo/CL_0000695 Cajal-Retzius cell http://purl.obolibrary.org/obo/CL_0012001 neuron of the forebrain A type of transient, early-born glutamatergic neuron located primarily in the marginal zone (future layer I) of the developing cerebral cortex and hippocampus in vertebrates. it is characterized by a bipolar morphology with an elongated soma, a single thick dendrite oriented toward the pial surface, and a long, thin axon that extends tangentially to form horizontal plexuses across the cortical surface. It is important for the multiple developmental processes including migration, dendritogenesis and synaptogenesis. It typically undergoes programmed cell death following cortical maturation with species- and region specific patterns of survival. In mice, it is predominantly observed in the hippocampal formation, particularly in the stratum lacunosum-moleculare and outer molecular layer of the dentate gyrus (van Bruggen et al., 2023). In contrast, in humans, a second morphologically distinct subpopulation emerges mid-gestation and persists postnatally, with surviving cells observed in the cortical sulci and the hippocampus. http://purl.obolibrary.org/obo/GO_0030103 vasopressin secretion http://purl.obolibrary.org/obo/GO_0030072 peptide hormone secretion The regulated release of vasopressin from secretory granules into the blood. http://purl.obolibrary.org/obo/CL_0000696 PP cell http://purl.obolibrary.org/obo/CL_0000167 peptide hormone secreting cell A cell that stores and secretes pancreatic polypeptide hormone. http://purl.obolibrary.org/obo/GO_0030141 secretory granule http://purl.obolibrary.org/obo/GO_0099503 secretory vesicle A small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. Secretory granules move towards the periphery of the cell and upon stimulation, their membranes fuse with the cell membrane, and their protein load is exteriorized. Processing of the contained protein may take place in secretory granules. http://purl.obolibrary.org/obo/CL_0000699 paraganglial type 1 cell http://purl.obolibrary.org/obo/CL_0000165 neuroendocrine cell A type of glomus or chief cell, is sensitive to hypoxia and produce catecholamines. http://purl.obolibrary.org/obo/GO_0030154 cell differentiation http://purl.obolibrary.org/obo/GO_0048869 cellular developmental process The cellular developmental process in which a relatively unspecialized cell, e.g. embryonic or regenerative cell, acquires specialized structural and/or functional features that characterize a specific cell. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. http://purl.obolibrary.org/obo/CL_0000700 dopaminergic neuron http://purl.obolibrary.org/obo/CL_4033050 catecholaminergic neuron A neuron that releases dopamine as a neurotransmitter. http://purl.obolibrary.org/obo/GO_0030155 regulation of cell adhesion http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of attachment of a cell to another cell or to the extracellular matrix. http://purl.obolibrary.org/obo/CL_0000701 paraganglia type 2 cell http://purl.obolibrary.org/obo/CL_0000630 supporting cell Supports paraganglial type 1 cell. http://purl.obolibrary.org/obo/GO_0030182 neuron differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a neuron. http://purl.obolibrary.org/obo/CL_0000703 sustentacular cell http://purl.obolibrary.org/obo/CL_0000630 supporting cell Cell that provides some or all mechanical, nutritional and phagocytic support to their neighbors. http://purl.obolibrary.org/obo/GO_0030183 B cell differentiation http://purl.obolibrary.org/obo/GO_0042113 B cell activation The process in which a precursor cell type acquires the specialized features of a B cell. A B cell is a lymphocyte of B lineage with the phenotype CD19-positive and capable of B cell mediated immunity. http://purl.obolibrary.org/obo/CL_0000704 endothelial tip cell http://purl.obolibrary.org/obo/CL_0000071 blood vessel endothelial cell A specialized endothelial cell that senses extracellular signals and guides the directed growth of blood vessels. http://purl.obolibrary.org/obo/GO_0030194 positive regulation of blood coagulation http://purl.obolibrary.org/obo/GO_0030193 regulation of blood coagulation Any process that activates or increases the frequency, rate or extent of blood coagulation. http://purl.obolibrary.org/obo/CL_0000706 choroid plexus epithelial cell http://purl.obolibrary.org/obo/CL_0000239 brush border epithelial cell A specialized ependymal cell that is part of the choroid plexus epithelium, responsible for producing cerebrospinal fluid (CSF) by selectively filtering and modifying blood plasma components before secreting it into the brain and spinal cord. This cell is characterized by a brush border on its apical surface, which enhances the secretion of CSF. http://purl.obolibrary.org/obo/GO_0030203 glycosaminoglycan metabolic process http://purl.obolibrary.org/obo/GO_0006022 aminoglycan metabolic process The chemical reactions and pathways involving glycosaminoglycans, any of a group of linear polysaccharides composed of repeating disaccharide units. http://purl.obolibrary.org/obo/CL_0000708 leptomeningeal cell http://purl.obolibrary.org/obo/CL_0002319 neural cell Stromal cell that forms the internal covering of the vertebrate brain and produces ECM for this and the choroid plexus. http://purl.obolibrary.org/obo/GO_0030216 keratinocyte differentiation http://purl.obolibrary.org/obo/GO_0009913 epidermal cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a keratinocyte. http://purl.obolibrary.org/obo/CL_0000710 neurecto-epithelial cell http://purl.obolibrary.org/obo/CL_0002077 ecto-epithelial cell Epithelial cells derived from neural plate and neural crest. http://purl.obolibrary.org/obo/GO_0030217 T cell differentiation http://purl.obolibrary.org/obo/GO_0042110 T cell activation The process in which a precursor cell type acquires characteristics of a more mature T-cell. A T cell is a type of lymphocyte whose definin characteristic is the expression of a T cell receptor complex. http://purl.obolibrary.org/obo/CL_0000711 cumulus granulosa cell http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure Cumulus cell is a specialized granulosa cell that surrounds and nourishes the oocyte. This cell-type surrounds the fully-grown oocyte to form a cumulus-oocyte complex (abbr. COC). The terms cumulus oophorus cells, cumulus granulosa cells, cumulus oophorous granulosa cells, granulosa-cumulus cells are used to make a distinction between this cell and the other functionally different subpopulation of granulosa cells at the wall of the Graafian follicle. http://purl.obolibrary.org/obo/GO_0030247 polysaccharide binding http://purl.obolibrary.org/obo/GO_0030246 carbohydrate binding Binding to a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically. http://purl.obolibrary.org/obo/CL_0000712 stratum granulosum cell http://purl.obolibrary.org/obo/CL_0000362 epidermal cell Any epidermal cell that is part of some stratum granulosum of epidermis. http://purl.obolibrary.org/obo/GO_0030261 chromosome condensation http://purl.obolibrary.org/obo/GO_0051276 chromosome organization The progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells. http://purl.obolibrary.org/obo/CL_0000715 embryonic crystal cell http://purl.obolibrary.org/obo/CL_0011008 embryonic hemocyte A crystal cell that derives from the embryonic head mesoderm. http://purl.obolibrary.org/obo/GO_0030334 regulation of cell migration http://purl.obolibrary.org/obo/GO_2000145 regulation of cell motility Any process that modulates the frequency, rate or extent of cell migration. http://purl.obolibrary.org/obo/CL_0000716 lymph gland crystal cell http://purl.obolibrary.org/obo/CL_0000735 lymph gland hemocyte A crystal cell that derives from the larval lymph gland. http://purl.obolibrary.org/obo/GO_0030335 positive regulation of cell migration http://purl.obolibrary.org/obo/GO_2000147 positive regulation of cell motility Any process that activates or increases the frequency, rate or extent of cell migration. http://purl.obolibrary.org/obo/CL_0000718 compound eye cone cell http://purl.obolibrary.org/obo/CL_0002319 neural cell A cell of an ommatidium that secretes lens materials. http://purl.obolibrary.org/obo/GO_0030336 negative regulation of cell migration http://purl.obolibrary.org/obo/GO_2000146 negative regulation of cell motility Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration. http://purl.obolibrary.org/obo/CL_0000723 somatic stem cell http://purl.obolibrary.org/obo/CL_0000034 stem cell A stem cell that can give rise to cell types of the body other than those of the germ-line. http://purl.obolibrary.org/obo/GO_0030473 nuclear migration along microtubule http://purl.obolibrary.org/obo/GO_0072384 organelle transport along microtubule The directed movement of the nucleus along microtubules within the cell, mediated by motor proteins. http://purl.obolibrary.org/obo/CL_0000724 heterocyst http://purl.obolibrary.org/obo/CL_0000725 nitrogen fixing cell A differentiated cell that functions as a site of nitrogen fixation under aerobic conditions. http://purl.obolibrary.org/obo/GO_0030554 adenyl nucleotide binding http://purl.obolibrary.org/obo/GO_0017076 purine nucleotide binding Binding to an adenyl nucleotide, an adenosine esterified with (ortho)phosphate. http://purl.obolibrary.org/obo/CL_0000725 nitrogen fixing cell http://purl.obolibrary.org/obo/CL_0000000 cell Any cell that is capable of some nitrogen fixation. http://purl.obolibrary.org/obo/GO_0030595 leukocyte chemotaxis http://purl.obolibrary.org/obo/GO_0050900 leukocyte migration The movement of a leukocyte in response to an external stimulus. http://purl.obolibrary.org/obo/CL_0000726 chlamydospore http://purl.obolibrary.org/obo/CL_0000605 fungal asexual spore An asexual 1-celled spore (primarily for perennation, not dissemination). Originates endogenously and singly within part of a pre-existing cell by the contraction of the protoplast. Possesses an inner secondary and often thickened hyaline or brown wall, usually impregnated with hydrophobic material. http://purl.obolibrary.org/obo/GO_0030667 secretory granule membrane http://purl.obolibrary.org/obo/GO_0030659 cytoplasmic vesicle membrane The lipid bilayer surrounding a secretory granule. http://purl.obolibrary.org/obo/GO_0030855 epithelial cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell, any of the cells making up an epithelium. http://purl.obolibrary.org/obo/CL_0000730 leading edge cell http://purl.obolibrary.org/obo/CL_0000066 epithelial cell A cell at the front of a migrating epithelial sheet. http://purl.obolibrary.org/obo/GO_0030857 negative regulation of epithelial cell differentiation http://purl.obolibrary.org/obo/GO_0030856 regulation of epithelial cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of epithelial cell differentiation. http://purl.obolibrary.org/obo/CL_0000731 urothelial cell http://purl.obolibrary.org/obo/CL_0000244 transitional epithelial cell A cell of a layer of transitional epithelium in the wall of the proximal urethra, bladder, ureter or renal pelvis, external to the lamina propria. http://purl.obolibrary.org/obo/GO_0030879 mammary gland development http://purl.obolibrary.org/obo/GO_0048732 gland development The process whose specific outcome is the progression of the mammary gland over time, from its formation to the mature structure. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk. Its development starts with the formation of the mammary line and ends as the mature gland cycles between nursing and weaning stages. http://purl.obolibrary.org/obo/CL_0000733 lymph gland plasmatocyte http://purl.obolibrary.org/obo/CL_0000735 lymph gland hemocyte A plasmatocyte that derives from the larval lymph gland. http://purl.obolibrary.org/obo/GO_0030952 establishment or maintenance of cytoskeleton polarity http://purl.obolibrary.org/obo/GO_0007010 cytoskeleton organization Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures. http://purl.obolibrary.org/obo/CL_0000735 lymph gland hemocyte http://purl.obolibrary.org/obo/CL_0000387 hemocyte (sensu Arthropoda) A hemocyte that derives from the larval lymph gland. http://purl.obolibrary.org/obo/GO_0031018 endocrine pancreas development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the endocrine pancreas over time, from its formation to the mature structure. The endocrine pancreas is made up of islet cells that produce insulin, glucagon and somatostatin. http://purl.obolibrary.org/obo/CL_0000737 striated muscle cell http://purl.obolibrary.org/obo/CL_0000187 muscle cell Muscle cell which has as its direct parts myofilaments organized into sarcomeres. http://purl.obolibrary.org/obo/GO_0031128 developmental induction http://purl.obolibrary.org/obo/GO_0032502 developmental process A developmental process involving two tissues in which one tissue (the inducer) produces a signal that directs cell fate commitment of cells in the second tissue (the responder). http://purl.obolibrary.org/obo/CL_0000738 leukocyte http://purl.obolibrary.org/obo/CL_0002242 nucleate cell An achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue. http://purl.obolibrary.org/obo/GO_0031175 neuron projection development http://purl.obolibrary.org/obo/GO_0120036 plasma membrane bounded cell projection organization The process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites). http://purl.obolibrary.org/obo/CL_0000740 retinal ganglion cell http://purl.obolibrary.org/obo/CL_0000540 neuron The set of neurons that receives neural inputs via bipolar, horizontal and amacrine cells. The axons of these cells make up the optic nerve. http://purl.obolibrary.org/obo/GO_0031252 cell leading edge http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure The area of a motile cell closest to the direction of movement. http://purl.obolibrary.org/obo/CL_0000741 spinal accessory motor neuron http://purl.obolibrary.org/obo/CL_0008039 lower motor neuron A motor neuron that is located in the cervical region of the spinal cord and selectively innervates the sternocleidmastoid or trapezius muscle. Unlike other motor neurons, they extend axons dorsally along lateral margins of the spinal cord. http://purl.obolibrary.org/obo/GO_0031333 negative regulation of protein-containing complex assembly http://purl.obolibrary.org/obo/GO_0051129 negative regulation of cellular component organization Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex assembly. http://purl.obolibrary.org/obo/CL_0000742 periarticular chondrocyte http://purl.obolibrary.org/obo/CL_1001607 articular chondrocyte A round chondrocyte that first differentiates in the late embryonic growth plate of bone. http://purl.obolibrary.org/obo/GO_0031334 positive regulation of protein-containing complex assembly http://purl.obolibrary.org/obo/GO_0051130 positive regulation of cellular component organization Any process that activates or increases the frequency, rate or extent of protein complex assembly. http://purl.obolibrary.org/obo/CL_0000743 hypertrophic chondrocyte http://purl.obolibrary.org/obo/CL_0001035 bone cell A chondrocyte that is part of the hypertrophic cartilage zone. This cell is significantly enlarged and characterised by high expression of type X collagen (COL10A1) in both humans and mice. It actively coordinates endochondral ossification by mineralising the extracellular matrix, attracting blood vessels via angiogenic signalling, and mediating the transition from cartilage to bone - often by transdifferentiating into an osteoblast rather than undergoing apoptosis. http://purl.obolibrary.org/obo/GO_0031341 regulation of cell killing http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of cell killing, the process in which a cell brings about the death of another cell, either in the same or a different organism. http://purl.obolibrary.org/obo/CL_0000744 columnar chondrocyte http://purl.obolibrary.org/obo/CL_0000138 chondrocyte A columnar chondrocyte that differentiates in the late embryonic growth plate of bone. Columnar chondrocytes vigorously proliferate and form columns in the growth plate. http://purl.obolibrary.org/obo/GO_0031342 negative regulation of cell killing http://purl.obolibrary.org/obo/GO_0031341 regulation of cell killing Any process that stops, prevents, or reduces the frequency, rate or extent of cell killing. http://purl.obolibrary.org/obo/CL_0000745 retina horizontal cell http://purl.obolibrary.org/obo/CL_0000099 interneuron A neuron that laterally connects other neurons in the inner nuclear layer of the retina. http://purl.obolibrary.org/obo/GO_0031343 positive regulation of cell killing http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the frequency, rate or extent of cell killing. http://purl.obolibrary.org/obo/CL_0000746 cardiac muscle cell http://purl.obolibrary.org/obo/CL_0002494 cardiocyte Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. In mammals, the contractile fiber resembles those of skeletal muscle but are only one third as large in diameter, are richer in sarcoplasm, and contain centrally located instead of peripheral nuclei. http://purl.obolibrary.org/obo/GO_0031348 negative regulation of defense response http://purl.obolibrary.org/obo/GO_0031347 regulation of defense response Any process that stops, prevents, or reduces the frequency, rate or extent of a defense response. http://purl.obolibrary.org/obo/CL_0000747 cyanophore http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell A pigment cell derived from the neural crest. Contains blue pigment of unknown chemical composition in fibrous organelles termed cyanosomes. This gives a blue appearance. http://purl.obolibrary.org/obo/GO_0031349 positive regulation of defense response http://purl.obolibrary.org/obo/GO_0031347 regulation of defense response Any process that activates or increases the frequency, rate or extent of a defense response. http://purl.obolibrary.org/obo/CL_0000748 retinal bipolar neuron http://purl.obolibrary.org/obo/CL_0009004 retinal cell A bipolar neuron found in the retina and having connections with photoreceptors cells and neurons in the inner plexiform layer. http://purl.obolibrary.org/obo/GO_0031410 cytoplasmic vesicle http://purl.obolibrary.org/obo/GO_0097708 intracellular vesicle A vesicle found in the cytoplasm of a cell. http://purl.obolibrary.org/obo/CL_0000749 ON-bipolar cell http://purl.obolibrary.org/obo/CL_0000748 retinal bipolar neuron A bipolar neuron found in the retina and having connections with photoreceptors cells and neurons in the inner half of the inner plexiform layer. These cells depolarize in response to light stimulation of their corresponding photoreceptors. http://purl.obolibrary.org/obo/GO_0031981 nuclear lumen http://purl.obolibrary.org/obo/GO_0070013 intracellular organelle lumen The volume enclosed by the nuclear inner membrane. http://purl.obolibrary.org/obo/CL_0000750 OFF-bipolar cell http://purl.obolibrary.org/obo/CL_0000748 retinal bipolar neuron A bipolar neuron found in the retina and having connections with photoreceptors cells and neurons in the outer half of the inner plexiform layer. These cells depolarize in response to light to dark transition. http://purl.obolibrary.org/obo/GO_0032091 negative regulation of protein binding http://purl.obolibrary.org/obo/GO_0051100 negative regulation of binding Any process that stops, prevents, or reduces the frequency, rate or extent of protein binding. http://purl.obolibrary.org/obo/CL_0000751 rod bipolar cell http://purl.obolibrary.org/obo/CL_0000749 ON-bipolar cell A bipolar neuron found in the retina that is synapsed by rod photoreceptor cells but not by cone photoreceptor cells. These neurons depolarize in response to light. http://purl.obolibrary.org/obo/GO_0032101 regulation of response to external stimulus http://purl.obolibrary.org/obo/GO_0048583 regulation of response to stimulus Any process that modulates the frequency, rate or extent of a response to an external stimulus. http://purl.obolibrary.org/obo/CL_0000752 cone retinal bipolar cell http://purl.obolibrary.org/obo/CL_0000748 retinal bipolar neuron A bipolar neuron found in the retina and having connections with cone photoreceptor cells and neurons in the inner plexiform layer. http://purl.obolibrary.org/obo/GO_0032103 positive regulation of response to external stimulus http://purl.obolibrary.org/obo/GO_0048584 positive regulation of response to stimulus Any process that activates, maintains or increases the rate of a response to an external stimulus. http://purl.obolibrary.org/obo/CL_0000753 type 1 cone bipolar cell (sensu Mus) http://purl.obolibrary.org/obo/CL_0000752 cone retinal bipolar cell An OFF-bipolar neuron found in the retina and having connections with cone photoreceptors cells and neurons in the outer half of the inner plexiform layer. The cell body of these cells is in the middle of the inner plexiform layer. The dendritic tree is stout and the axon terminates in sublamina 1. The axonal terminal is wide and has only a few varicosities. http://purl.obolibrary.org/obo/GO_0032271 regulation of protein polymerization http://purl.obolibrary.org/obo/GO_0043254 regulation of protein-containing complex assembly Any process that modulates the frequency, rate or extent of the process of creating protein polymers. http://purl.obolibrary.org/obo/CL_0000754 type 2 cone bipolar cell (sensu Mus) http://purl.obolibrary.org/obo/CL_0000752 cone retinal bipolar cell An OFF-bipolar neuron found in the retina and having connections with cone photoreceptors cells and neurons in the outer half of the inner plexiform layer. The dendritic tree is not well filled and the dendrites are more delicate than in type 1 cells. The axon terminal is bushier and exhibits a dense plexus of varicosities in the inner part of sublamina 1 (Ghosh et al., 2004). It can be differentiated from other retinal bipolar neurons by its expression of marker genes: Neto1, Lhx3 and Irx-6 (Shekhar, 2016). http://purl.obolibrary.org/obo/GO_0032432 actin filament bundle http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure An assembly of actin filaments that are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness. http://purl.obolibrary.org/obo/CL_0000755 type 3 cone bipolar cell (sensu Mus) http://purl.obolibrary.org/obo/CL_0000752 cone retinal bipolar cell An OFF-bipolar neuron found in the retina and having connections with cone photoreceptors cells and neurons in the outer half of the inner plexiform layer. The dendritic tree is delicate and the dendritic tips appear small when compared with type 1 cells. The axon terminal is stratified and restricted to sublamina 2 of the inner plexiform layer. http://purl.obolibrary.org/obo/GO_0032501 multicellular organismal process http://purl.obolibrary.org/obo/GO_0008150 biological_process Any biological process, occurring at the level of a multicellular organism, pertinent to its function. http://purl.obolibrary.org/obo/CL_0000756 type 4 cone bipolar cell (sensu Mus) http://purl.obolibrary.org/obo/CL_0000752 cone retinal bipolar cell An OFF-bipolar neuron found in the retina and having connections with cone photoreceptors cells and neurons in the outer half of the inner plexiform layer. The cell has a diffuse axon terminal with varicosities in sublaminae 1 and 2 of the inner plexiform layer. http://purl.obolibrary.org/obo/GO_0032502 developmental process http://purl.obolibrary.org/obo/GO_0008150 biological_process A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition. http://purl.obolibrary.org/obo/CL_0000757 type 5 cone bipolar cell (sensu Mus) http://purl.obolibrary.org/obo/CL_0000752 cone retinal bipolar cell An ON-bipolar neuron found in the retina and having connections with cone photoreceptors cells and neurons in the inner half of the inner plexiform layer. The axon terminal is restricted to sublamina 3 of the inner plexiform layer. It is narrowly stratified and branched. The dendritic tree has many delicate branches. http://purl.obolibrary.org/obo/GO_0032774 RNA biosynthetic process http://purl.obolibrary.org/obo/GO_0016070 RNA metabolic process The chemical reactions and pathways resulting in the formation of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. Includes polymerization of ribonucleotide monomers. Refers not only to transcription but also to e.g. viral RNA replication. http://purl.obolibrary.org/obo/CL_0000758 type 6 cone bipolar cell (sensu Mus) http://purl.obolibrary.org/obo/CL_0000752 cone retinal bipolar cell An ON-bipolar neuron found in the retina and having connections with cone photoreceptors cells and neurons in the inner half of the inner plexiform layer. The cell has a loose, delicate axon terminal that opens in sublamina 3 of the inner plexiform layer and descends into sublamina 4. http://purl.obolibrary.org/obo/GO_0032781 positive regulation of ATP-dependent activity http://purl.obolibrary.org/obo/GO_0043462 regulation of ATP-dependent activity Any process that activates or increases the rate of an ATP-dependent activity. http://purl.obolibrary.org/obo/CL_0000759 type 7 cone bipolar cell (sensu Mus) http://purl.obolibrary.org/obo/CL_0000752 cone retinal bipolar cell An ON-bipolar neuron found in the retina and having connections with cone photoreceptors cells and neurons in the inner half of the inner plexiform layer. The axon terminal is narrowly stratified and are found just below a calretinin-expressing band in sublamina 4 of the inner plexiform layer. http://purl.obolibrary.org/obo/GO_0032940 secretion by cell http://purl.obolibrary.org/obo/GO_0046903 secretion The controlled release of a substance by a cell. http://purl.obolibrary.org/obo/CL_0000760 type 8 cone bipolar cell (sensu Mus) http://purl.obolibrary.org/obo/CL_0000752 cone retinal bipolar cell An ON-bipolar neuron found in the retina and having connections with cone photoreceptors cells and neurons in the inner half of the inner plexiform layer. This cell has the widest dendritic field and the widest axon terminal of all retinal bipolar cells. The axon terminal is delicate and stratified through sublaminae 4 and 5 of the inner plexiform layer. http://purl.obolibrary.org/obo/GO_0032984 protein-containing complex disassembly http://purl.obolibrary.org/obo/GO_0043933 protein-containing complex organization The disaggregation of a protein-containing macromolecular complex into its constituent components. http://purl.obolibrary.org/obo/CL_0000761 type 9 cone bipolar cell (sensu Mus) http://purl.obolibrary.org/obo/CL_0000752 cone retinal bipolar cell An ON-bipolar neuron found in the retina and having connections with cone photoreceptors cells and neurons in the inner half of the inner plexiform layer. The dendritic tree is wide and the dendritic convergence indicates cone selectivity. The axon terminal is sparsely branched and terminates in sublamina 5 of the inner plexiform layer. http://purl.obolibrary.org/obo/GO_0032988 protein-RNA complex disassembly http://purl.obolibrary.org/obo/GO_0071826 protein-RNA complex organization The disaggregation of a protein-RNA complex into its constituent components. http://purl.obolibrary.org/obo/CL_0000762 nucleated thrombocyte http://purl.obolibrary.org/obo/CL_0000763 myeloid cell A nucleated blood cell involved in coagulation, typically seen in birds and other non-mammalian vertebrates. http://purl.obolibrary.org/obo/GO_0032989 cellular anatomical entity morphogenesis http://purl.obolibrary.org/obo/GO_0016043 cellular component organization The process in which a cellular entity is generated and organized. A cellular entity has granularity above the level of a protein complex but below that of an anatomical system. http://purl.obolibrary.org/obo/CL_0000763 myeloid cell http://purl.obolibrary.org/obo/CL_0000988 hematopoietic cell A cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroid lineage. http://purl.obolibrary.org/obo/GO_0032991 protein-containing complex http://purl.obolibrary.org/obo/GO_0005575 cellular_component A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together. http://purl.obolibrary.org/obo/CL_0000764 erythroid lineage cell http://purl.obolibrary.org/obo/CL_0000763 myeloid cell A immature or mature cell in the lineage leading to and including erythrocytes. http://purl.obolibrary.org/obo/GO_0033028 myeloid cell apoptotic process http://purl.obolibrary.org/obo/GO_0006915 apoptotic process Any apoptotic process in a myeloid cell, a cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroid lineage. http://purl.obolibrary.org/obo/CL_0000765 erythroblast http://purl.obolibrary.org/obo/CL_0011026 progenitor cell A nucleated precursor of an erythrocyte that lacks hematopoietic lineage markers. http://purl.obolibrary.org/obo/GO_0033043 regulation of organelle organization http://purl.obolibrary.org/obo/GO_0051128 regulation of cellular component organization Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle. http://purl.obolibrary.org/obo/CL_0000766 myeloid leukocyte http://purl.obolibrary.org/obo/CL_0000763 myeloid cell A cell of the monocyte, granulocyte, or mast cell lineage. http://purl.obolibrary.org/obo/GO_0033293 monocarboxylic acid binding http://purl.obolibrary.org/obo/GO_0031406 carboxylic acid binding Binding to a monocarboxylic acid, any organic acid containing one carboxyl (COOH) group or anion (COO-). http://purl.obolibrary.org/obo/CL_0000767 basophil http://purl.obolibrary.org/obo/CL_0000094 granulocyte Any of the immature or mature forms of a granular leukocyte that in its mature form has an irregularly shaped, pale-staining nucleus that is partially constricted into two lobes, and with cytoplasm that contains coarse, bluish-black granules of variable size. Basophils contain vasoactive amines such as histamine and serotonin, which are released on appropriate stimulation. A basophil is CD123-positive, CD193-positive, CD203c-positive, and FceRIa-positive. http://purl.obolibrary.org/obo/GO_0033363 secretory granule organization http://purl.obolibrary.org/obo/GO_0016050 vesicle organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule. A secretory granule is a small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. http://purl.obolibrary.org/obo/CL_0000768 immature basophil http://purl.obolibrary.org/obo/CL_0000767 basophil Any of the immature forms of a basophil, in which basophilic specific granules are present but other phenotypic features of the mature form may be lacking. http://purl.obolibrary.org/obo/GO_0033554 cellular response to stress http://purl.obolibrary.org/obo/GO_0006950 response to stress Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). http://purl.obolibrary.org/obo/CL_0000769 basophilic metamyelocyte http://purl.obolibrary.org/obo/CL_0002192 metamyelocyte A basophil precursor in the granulocytic series, being a cell intermediate in development between a basophilic myelocyte and a band form basophil. The nucleus becomes indented where the indentation is smaller than half the distance to the farthest nuclear margin; chromatin becomes coarse and clumped; specific granules predominate while primary granules are rare. Markers are CD11b-positive, CD15-positive, CD16-positive, CD24-positive, CD33-positive, and CD13-positive. http://purl.obolibrary.org/obo/GO_0034599 cellular response to oxidative stress http://purl.obolibrary.org/obo/GO_0062197 cellular response to chemical stress Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals. http://purl.obolibrary.org/obo/CL_0000770 band form basophil http://purl.obolibrary.org/obo/CL_0000768 immature basophil A late basophilic metamyelocyte in which the nucleus is in the form of a curved or coiled band, not having acquired the typical multilobar shape of the mature basophil. http://purl.obolibrary.org/obo/GO_0034706 sodium channel complex http://purl.obolibrary.org/obo/GO_0034703 cation channel complex An ion channel complex through which sodium ions pass. http://purl.obolibrary.org/obo/CL_0000771 eosinophil http://purl.obolibrary.org/obo/CL_0000094 granulocyte Any of the immature or mature forms of a granular leukocyte with a nucleus that usually has two lobes connected by one or more slender threads of chromatin, and cytoplasm containing coarse, round granules that are uniform in size and which can be stained by the dye eosin. Eosinophils are CD9-positive, CD191-positive, and CD193-positive. http://purl.obolibrary.org/obo/GO_0034755 iron ion transmembrane transport http://purl.obolibrary.org/obo/GO_0098655 monoatomic cation transmembrane transport A process in which an iron ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/CL_0000772 immature eosinophil http://purl.obolibrary.org/obo/CL_0000771 eosinophil Any of the immature forms of an eosinophil, in which eosinophilic specific granules are present but other phenotypic features of the mature form may be lacking. http://purl.obolibrary.org/obo/GO_0035050 embryonic heart tube development http://purl.obolibrary.org/obo/GO_0060429 epithelium development The process whose specific outcome is the progression of the embryonic heart tube over time, from its formation to the mature structure. The heart tube forms as the heart rudiment from the heart field. http://purl.obolibrary.org/obo/CL_0000773 eosinophilic metamyelocyte http://purl.obolibrary.org/obo/CL_0002192 metamyelocyte A eosinophil precursor in the granulocytic series, being a cell intermediate in development between a eosinophilic myelocyte and a band form eosinophil. The nucleus becomes indented where the indentation is smaller than half the distance to the farthest nuclear margin; chromatin becomes coarse and clumped; specific granules predominate while primary granules are rare. Markers are integrin alpha-M-positive, fucosyltransferase FUT4-positive, low affinity immunoglobulin gamma Fc region receptor III-positive, CD33-positive, CD24-positive and aminopeptidase N-negative. http://purl.obolibrary.org/obo/GO_0035051 cardiocyte differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell that will form part of the cardiac organ of an individual. http://purl.obolibrary.org/obo/CL_0000774 band form eosinophil http://purl.obolibrary.org/obo/CL_0000772 immature eosinophil A late eosinophilic metamyelocyte in which the nucleus is in the form of a curved or coiled band, not having acquired the typical multilobar shape of the mature eosinophil. http://purl.obolibrary.org/obo/CL_0000775 neutrophil http://purl.obolibrary.org/obo/CL_0000094 granulocyte Any of the immature or mature forms of a granular leukocyte that in its mature form has a nucleus with three to five lobes connected by slender threads of chromatin, and cytoplasm containing fine inconspicuous granules and stainable by neutral dyes. http://purl.obolibrary.org/obo/CL_0000776 immature neutrophil http://purl.obolibrary.org/obo/CL_0000775 neutrophil Any of the immature forms of a neutrophil in which neutrophilic specific granules are present but other phenotypic features of the mature form may be lacking. http://purl.obolibrary.org/obo/CL_0000777 mesangial phagocyte http://purl.obolibrary.org/obo/CL_0000864 tissue-resident macrophage A tissue-resident macrophage of the renal glomerular mesangium involved in the disposal and degradation of filtration residues, presentation of antigen to T cells and in tissue remodeling. http://purl.obolibrary.org/obo/CL_0000778 mononuclear osteoclast http://purl.obolibrary.org/obo/CL_0000113 mononuclear phagocyte A specialized mononuclear osteoclast associated with the absorption and removal of bone, precursor of multinuclear osteoclasts. http://purl.obolibrary.org/obo/CL_0000779 multinuclear osteoclast http://purl.obolibrary.org/obo/CL_0000783 multinucleated phagocyte A specialized multinuclear osteoclast, forming a syncytium through the fusion of mononuclear precursor cells, associated with the absorption and removal of bone. http://purl.obolibrary.org/obo/CL_0000780 multinuclear odontoclast http://purl.obolibrary.org/obo/CL_0000779 multinuclear osteoclast A specialized multinuclear osteoclast associated with the absorption and removal of cementum. http://purl.obolibrary.org/obo/CL_0000781 mononuclear odontoclast http://purl.obolibrary.org/obo/CL_0000778 mononuclear osteoclast A specialized mononuclear osteoclast associated with the absorption and removal of cementum. http://purl.obolibrary.org/obo/CL_0000782 myeloid dendritic cell http://purl.obolibrary.org/obo/CL_0000990 conventional dendritic cell A dendritic cell of the myeloid lineage. http://purl.obolibrary.org/obo/CL_0000783 multinucleated phagocyte http://purl.obolibrary.org/obo/CL_0000518 phagocyte (sensu Vertebrata) A phagocyte formed by the fusion of mononuclear phagocytes. http://purl.obolibrary.org/obo/CL_0000784 plasmacytoid dendritic cell http://purl.obolibrary.org/obo/CL_0000451 dendritic cell A dendritic cell type of distinct morphology, localization, and surface marker expression (CD123-positive) from other dendritic cell types and associated with early stage immune responses, particularly the release of physiologically abundant amounts of type I interferons in response to infection. http://purl.obolibrary.org/obo/CL_0000785 mature B cell http://purl.obolibrary.org/obo/CL_0001201 B cell, CD19-positive A B cell that is mature, having left the bone marrow. Initially, these cells are IgM-positive and IgD-positive, and they can be activated by antigen. http://purl.obolibrary.org/obo/GO_0035282 segmentation http://purl.obolibrary.org/obo/GO_0003002 regionalization The regionalization process that divides an organism or part of an organism into a series of semi-repetitive parts, or segments, often arranged along a longitudinal axis. http://purl.obolibrary.org/obo/CL_0000786 plasma cell http://purl.obolibrary.org/obo/CL_0000946 antibody secreting cell A terminally differentiated, post-mitotic, antibody secreting cell of the B cell lineage with the phenotype CD138-positive, surface immunonoglobulin-negative, and MHC Class II-negative. Plasma cells are oval or round with extensive rough endoplasmic reticulum, a well-developed Golgi apparatus, and a round nucleus having a characteristic cartwheel heterochromatin pattern and are devoted to producing large amounts of immunoglobulin. http://purl.obolibrary.org/obo/GO_0035556 intracellular signal transduction http://purl.obolibrary.org/obo/GO_0007165 signal transduction The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell. http://purl.obolibrary.org/obo/CL_0000787 memory B cell http://purl.obolibrary.org/obo/CL_0000785 mature B cell A memory B cell is a mature B cell that is long-lived, readily activated upon re-encounter of its antigenic determinant, and has been selected for expression of higher affinity immunoglobulin. This cell type has the phenotype CD19-positive, CD20-positive, MHC Class II-positive, and CD138-negative. http://purl.obolibrary.org/obo/GO_0035590 purinergic nucleotide receptor signaling pathway http://purl.obolibrary.org/obo/GO_0007166 cell surface receptor signaling pathway The series of molecular signals initiated by an extracellular purine nucleotide binding to its receptor, and ending with the regulation of a downstream cellular process, e.g. transcription. http://purl.obolibrary.org/obo/CL_0000788 naive B cell http://purl.obolibrary.org/obo/CL_0000785 mature B cell A naive B cell is a mature B cell that has the phenotype surface IgD-positive, surface IgM-positive, CD20-positive, CD27-negative and that has not yet been activated by antigen in the periphery. http://purl.obolibrary.org/obo/CL_0000789 alpha-beta T cell http://purl.obolibrary.org/obo/CL_0000084 T cell A T cell that expresses an alpha-beta T cell receptor complex. http://purl.obolibrary.org/obo/GO_0035850 epithelial cell differentiation involved in kidney development http://purl.obolibrary.org/obo/GO_0061005 cell differentiation involved in kidney development The process in which relatively unspecialized cells acquire specialized structural and/or functional features of an epithelial cell that characterize the cells of the kidney as it progresses from its formation to the mature state. http://purl.obolibrary.org/obo/CL_0000790 immature alpha-beta T cell http://purl.obolibrary.org/obo/CL_0002420 immature T cell An alpha-beta T cell that has an immature phenotype and has not completed T cell selection. http://purl.obolibrary.org/obo/GO_0035883 enteroendocrine cell differentiation http://purl.obolibrary.org/obo/GO_0030855 epithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of an enteroendocrine cell. Enteroendocrine cells are hormonally active epithelial cells in the gut that constitute the diffuse neuroendocrine system. http://purl.obolibrary.org/obo/CL_0000791 mature alpha-beta T cell http://purl.obolibrary.org/obo/CL_0002419 mature T cell A alpha-beta T cell that has a mature phenotype. http://purl.obolibrary.org/obo/GO_0035932 aldosterone secretion http://purl.obolibrary.org/obo/GO_0035931 mineralocorticoid secretion The regulated release of aldosterone into the circulatory system. Aldosterone is a pregnane-based steroid hormone produced by the outer-section (zona glomerulosa) of the adrenal cortex in the adrenal gland, and acts on the distal tubules and collecting ducts of the kidney to cause the conservation of sodium, secretion of potassium, increased water retention, and increased blood pressure. The overall effect of aldosterone is to increase reabsorption of ions and water in the kidney. http://purl.obolibrary.org/obo/CL_0000792 CD4-positive, CD25-positive, alpha-beta regulatory T cell http://purl.obolibrary.org/obo/CL_0000815 regulatory T cell A CD4-positive, CD25-positive, alpha-beta T cell that regulates overall immune responses as well as the responses of other T cell subsets through direct cell-cell contact and cytokine release. http://purl.obolibrary.org/obo/GO_0035987 endodermal cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of an endoderm cell, a cell of the inner of the three germ layers of the embryo. http://purl.obolibrary.org/obo/CL_0000793 CD4-positive, alpha-beta intraepithelial T cell http://purl.obolibrary.org/obo/CL_0000797 alpha-beta intraepithelial T cell A CD4-positive, alpha-beta T cell that is found in the columnar epithelium of the gastrointestinal tract. http://purl.obolibrary.org/obo/GO_0035989 tendon development http://purl.obolibrary.org/obo/GO_0061448 connective tissue development The process whose specific outcome is the progression of a tendon over time, from its formation to the mature structure. A tendon is a fibrous, strong, connective tissue that connects muscle to bone or integument and is capable of withstanding tension. Tendons and muscles work together to exert a pulling force. http://purl.obolibrary.org/obo/CL_0000794 CD8-positive, alpha-beta cytotoxic T cell http://purl.obolibrary.org/obo/CL_0000625 CD8-positive, alpha-beta T cell A CD8-positive, alpha-beta T cell that is capable of killing target cells in an antigen specific manner with the phenotype perforin-positive and granzyme B-positive. http://purl.obolibrary.org/obo/GO_0036072 direct ossification http://purl.obolibrary.org/obo/GO_0001503 ossification The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance, that does not require the replacement of preexisting tissues. http://purl.obolibrary.org/obo/CL_0000795 CD8-positive, alpha-beta regulatory T cell http://purl.obolibrary.org/obo/CL_0000815 regulatory T cell A CD8-positive, alpha-beta T cell that regulates overall immune responses as well as the responses of other T cell subsets through direct cell-cell contact and cytokine release. http://purl.obolibrary.org/obo/GO_0036075 replacement ossification http://purl.obolibrary.org/obo/GO_0001503 ossification Ossification that requires the replacement of a preexisting tissue prior to bone tissue formation. http://purl.obolibrary.org/obo/CL_0000796 CD8-alpha-beta-positive, alpha-beta intraepithelial T cell http://purl.obolibrary.org/obo/CL_0000797 alpha-beta intraepithelial T cell A alpha-beta intraepithelial T cell found in the columnar epithelium of the gastrointestinal tract. Intraepithelial T cells often have distinct developmental pathways and activation requirements. http://purl.obolibrary.org/obo/GO_0036093 germ cell proliferation http://purl.obolibrary.org/obo/GO_0008283 cell population proliferation The multiplication or reproduction of germ cells, reproductive cells in multicellular organisms, resulting in the expansion of a cell population. http://purl.obolibrary.org/obo/CL_0000797 alpha-beta intraepithelial T cell http://purl.obolibrary.org/obo/CL_0020035 intestinal intraepithelial lymphocyte A mature alpha-beta T cell of the columnar epithelium of the gastrointestinal tract. Intraepithelial T cells often have distinct developmental pathways and activation requirements. http://purl.obolibrary.org/obo/GO_0036094 small molecule binding http://purl.obolibrary.org/obo/GO_0005488 binding Binding to a small molecule, any low molecular weight, monomeric, non-encoded molecule. http://purl.obolibrary.org/obo/CL_0000798 gamma-delta T cell http://purl.obolibrary.org/obo/CL_0000084 T cell A T cell that expresses a gamma-delta T cell receptor complex. http://purl.obolibrary.org/obo/GO_0036293 response to decreased oxygen levels http://purl.obolibrary.org/obo/GO_0070482 response to oxygen levels Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting a decline in the level of oxygen. http://purl.obolibrary.org/obo/CL_0000799 immature gamma-delta T cell http://purl.obolibrary.org/obo/CL_0002420 immature T cell A gamma-delta T cell that has an immature phenotype. http://purl.obolibrary.org/obo/GO_0036303 lymph vessel morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structures of lymph vessels are generated and organized. The lymph vessel is the vasculature carrying lymph. http://purl.obolibrary.org/obo/GO_0036336 dendritic cell migration http://purl.obolibrary.org/obo/GO_0071674 mononuclear cell migration The movement of a dendritic cell within or between different tissues and organs of the body. http://purl.obolibrary.org/obo/CL_0000800 mature gamma-delta T cell http://purl.obolibrary.org/obo/CL_0002419 mature T cell A gamma-delta T cell that has a mature phenotype. These cells can be found in tissues and circulation where they express unique TCR repertoire depending on their location. http://purl.obolibrary.org/obo/GO_0038023 signaling receptor activity http://purl.obolibrary.org/obo/GO_0060089 molecular transducer activity Receiving a signal and transmitting it in the cell to initiate a change in cell activity. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response. http://purl.obolibrary.org/obo/GO_0040007 growth http://purl.obolibrary.org/obo/GO_0008150 biological_process The increase in size or mass of an entire organism, a part of an organism or a cell. http://purl.obolibrary.org/obo/CL_0000801 gamma-delta intraepithelial T cell http://purl.obolibrary.org/obo/CL_0020035 intestinal intraepithelial lymphocyte A mature gamma-delta T cell that is found in the columnar epithelium of the gastrointestinal tract. These cells participate in mucosal immune responses. http://purl.obolibrary.org/obo/GO_0040008 regulation of growth http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process Any process that modulates the frequency, rate or extent of the growth of all or part of an organism so that it occurs at its proper speed, either globally or in a specific part of the organism's development. http://purl.obolibrary.org/obo/CL_0000802 CD8-alpha alpha positive, gamma-delta intraepithelial T cell http://purl.obolibrary.org/obo/CL_0000801 gamma-delta intraepithelial T cell A gamma-delta intraepithelial T cell that has the phenotype CD8-alpha alpha-positive. http://purl.obolibrary.org/obo/CL_0000803 CD4-negative CD8-negative gamma-delta intraepithelial T cell http://purl.obolibrary.org/obo/CL_0000801 gamma-delta intraepithelial T cell A gamma-delta intraepithelial T cell that has the phenotype CD4-negative and CD8-negative. http://purl.obolibrary.org/obo/GO_0042060 wound healing http://purl.obolibrary.org/obo/GO_0009611 response to wounding The series of events that restore integrity to a damaged tissue, following an injury. http://purl.obolibrary.org/obo/GO_0042074 cell migration involved in gastrulation http://purl.obolibrary.org/obo/GO_0001667 ameboidal-type cell migration The migration of individual cells within the blastocyst to help establish the multi-layered body plan of the organism (gastrulation). For example, the migration of cells from the surface to the interior of the embryo (ingression). http://purl.obolibrary.org/obo/CL_0000805 immature single positive thymocyte http://purl.obolibrary.org/obo/CL_0000893 thymocyte A thymocyte that has the phenotype CD4-negative, CD8-positive, CD44-negative, CD25-negative, and pre-TCR-positive. http://purl.obolibrary.org/obo/CL_0000806 DN2 thymocyte http://purl.obolibrary.org/obo/CL_0002489 double negative thymocyte A thymocyte that has the phenotype CD4-negative, CD8-negative, CD44-positive, and CD25-positive. http://purl.obolibrary.org/obo/GO_0042088 T-helper 1 type immune response http://purl.obolibrary.org/obo/GO_0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains An immune response which is associated with resistance to intracellular bacteria, fungi, and protozoa, and pathological conditions such as arthritis, and which is typically orchestrated by the production of particular cytokines by T-helper 1 cells, most notably interferon-gamma, IL-2, and lymphotoxin. http://purl.obolibrary.org/obo/CL_0000807 DN3 thymocyte http://purl.obolibrary.org/obo/CL_0002489 double negative thymocyte A thymocyte that has the phenotype CD4-negative, CD8-negative, CD44-negative, and CD25-positive and expressing the T cell receptor beta-chain in complex with the pre-T cell receptor alpha chain. http://purl.obolibrary.org/obo/GO_0042092 type 2 immune response http://purl.obolibrary.org/obo/GO_0006955 immune response An immune response which is associated with resistance to extracellular organisms such as helminths and pathological conditions such as allergy, which is orchestrated by the production of particular cytokines, most notably IL-4, IL-5, IL-10, and IL-13, by any of a variety of cell types including T-helper 2 cells, eosinophils, basophils, mast cells, and nuocytes, resulting in enhanced production of certain antibody isotypes and other effects. http://purl.obolibrary.org/obo/CL_0000808 DN4 thymocyte http://purl.obolibrary.org/obo/CL_0002489 double negative thymocyte A thymocyte that has the phenotype CD4-negative, CD8-negative, CD44-negative, CD25-negative, and pre-TCR-positive. http://purl.obolibrary.org/obo/CL_0000809 double-positive, alpha-beta thymocyte http://purl.obolibrary.org/obo/CL_0000893 thymocyte A thymocyte expressing the alpha-beta T cell receptor complex as well as both the CD4 and CD8 coreceptors. http://purl.obolibrary.org/obo/GO_0042093 T-helper cell differentiation http://purl.obolibrary.org/obo/GO_0043367 CD4-positive, alpha-beta T cell differentiation The process in which a relatively unspecialized thymocyte acquires specialized features of a T-helper cell. http://purl.obolibrary.org/obo/CL_0000810 CD4-positive, alpha-beta thymocyte http://purl.obolibrary.org/obo/CL_0000893 thymocyte An immature alpha-beta T cell that is located in the thymus and is CD4-positive and CD8-negative. http://purl.obolibrary.org/obo/GO_0042098 T cell proliferation http://purl.obolibrary.org/obo/GO_0046651 lymphocyte proliferation The expansion of a T cell population by cell division. Follows T cell activation. http://purl.obolibrary.org/obo/CL_0000811 CD8-positive, alpha-beta thymocyte http://purl.obolibrary.org/obo/CL_0000893 thymocyte An immature alpha-beta T cell that is located in the thymus and is CD8-positive and CD4-negative. http://purl.obolibrary.org/obo/GO_0042100 B cell proliferation http://purl.obolibrary.org/obo/GO_0046651 lymphocyte proliferation The expansion of a B cell population by cell division. Follows B cell activation. http://purl.obolibrary.org/obo/CL_0000813 memory T cell http://purl.obolibrary.org/obo/CL_0002419 mature T cell A long-lived, antigen-experienced T cell that has acquired a memory phenotype including distinct surface markers and the ability to differentiate into an effector T cell upon antigen reexposure. http://purl.obolibrary.org/obo/GO_0042110 T cell activation http://purl.obolibrary.org/obo/GO_0046649 lymphocyte activation The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. http://purl.obolibrary.org/obo/CL_0000814 mature NK T cell http://purl.obolibrary.org/obo/CL_0000791 mature alpha-beta T cell A mature alpha-beta T cell of a distinct lineage that bears natural killer markers and a T cell receptor specific for a limited set of ligands. NK T cells have activation and regulatory roles particularly early in an immune response. http://purl.obolibrary.org/obo/GO_0042113 B cell activation http://purl.obolibrary.org/obo/GO_0046649 lymphocyte activation The change in morphology and behavior of a mature or immature B cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. http://purl.obolibrary.org/obo/CL_0000815 regulatory T cell http://purl.obolibrary.org/obo/CL_0002419 mature T cell A T cell which regulates overall immune responses as well as the responses of other T cell subsets through direct cell-cell contact and cytokine release. http://purl.obolibrary.org/obo/GO_0042116 macrophage activation http://purl.obolibrary.org/obo/GO_0002274 myeloid leukocyte activation A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. http://purl.obolibrary.org/obo/CL_0000816 immature B cell http://purl.obolibrary.org/obo/CL_0001201 B cell, CD19-positive An immature B cell is a B cell that has the phenotype surface IgM-positive and surface IgD-negative, and have not undergone class immunoglobulin class switching or peripheral encounter with antigen and activation. http://purl.obolibrary.org/obo/CL_0000817 precursor B cell http://purl.obolibrary.org/obo/CL_0001201 B cell, CD19-positive A precursor B cell is a B cell with the phenotype CD10-positive. http://purl.obolibrary.org/obo/GO_0042117 monocyte activation http://purl.obolibrary.org/obo/GO_0002274 myeloid leukocyte activation The change in morphology and behavior of a monocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. http://purl.obolibrary.org/obo/GO_0042118 endothelial cell activation http://purl.obolibrary.org/obo/GO_0001775 cell activation The change in morphology and behavior of an endothelial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. http://purl.obolibrary.org/obo/CL_0000818 transitional stage B cell http://purl.obolibrary.org/obo/CL_0001201 B cell, CD19-positive An immature B cell of an intermediate stage between the pre-B cell stage and the mature naive stage with the phenotype surface IgM-positive and CD19-positive, and are subject to the process of B cell selection. A transitional B cell migrates from the bone marrow into the peripheral circulation, and then to the spleen. http://purl.obolibrary.org/obo/GO_0042119 neutrophil activation http://purl.obolibrary.org/obo/GO_0036230 granulocyte activation The change in morphology and behavior of a neutrophil resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. http://purl.obolibrary.org/obo/CL_0000819 B-1 B cell http://purl.obolibrary.org/obo/CL_0000785 mature B cell A B cell of distinct lineage and surface marker expression. B-1 B cells are thought to be the primary source of natural IgM immunoglobulin, that is, IgM produced in large quantities without prior antigenic stimulation and generally reactive against various microorganisms, as well as the source of T-independent IgA immunoglobulin in the mucosal areas. These cells are CD43-positive. http://purl.obolibrary.org/obo/GO_0042127 regulation of cell population proliferation http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of cell proliferation. http://purl.obolibrary.org/obo/GO_0042159 lipoprotein catabolic process http://purl.obolibrary.org/obo/GO_0042157 lipoprotein metabolic process The chemical reactions and pathways resulting in the breakdown of any conjugated, water-soluble protein in which the covalently attached nonprotein group consists of a lipid or lipids. http://purl.obolibrary.org/obo/CL_0000820 B-1a B cell http://purl.obolibrary.org/obo/CL_0000819 B-1 B cell A B-1 B cell that has the phenotype CD5-positive. http://purl.obolibrary.org/obo/CL_0000821 B-1b B cell http://purl.obolibrary.org/obo/CL_0000819 B-1 B cell A B-1 B cell that has the phenotype CD5-negative, but having other phenotypic attributes of a B-1 B cell. http://purl.obolibrary.org/obo/GO_0042221 response to chemical http://purl.obolibrary.org/obo/GO_0050896 response to stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus. http://purl.obolibrary.org/obo/CL_0000822 B-2 B cell http://purl.obolibrary.org/obo/CL_0000785 mature B cell A conventional B cell subject to antigenic stimulation and dependent on T cell help and with a distinct surface marker expression pattern from B-1 B cells. These cells are CD43-negative. http://purl.obolibrary.org/obo/GO_0042254 ribosome biogenesis http://purl.obolibrary.org/obo/GO_0022613 ribonucleoprotein complex biogenesis A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits; includes transport to the sites of protein synthesis. http://purl.obolibrary.org/obo/CL_0000823 immature natural killer cell http://purl.obolibrary.org/obo/CL_0001082 immature innate lymphoid cell A natural killer cell that is developmentally immature and expresses natural killer cell receptors (NKR). http://purl.obolibrary.org/obo/GO_0042255 ribosome assembly http://purl.obolibrary.org/obo/GO_0140694 membraneless organelle assembly The aggregation, arrangement and bonding together of the mature ribosome and of its subunits. http://purl.obolibrary.org/obo/CL_0000824 mature natural killer cell http://purl.obolibrary.org/obo/CL_0000623 natural killer cell A natural killer cell that is developmentally mature and expresses a variety of inhibitory and activating receptors that recognize MHC class I and other stress related molecules. http://purl.obolibrary.org/obo/GO_0042267 natural killer cell mediated cytotoxicity http://purl.obolibrary.org/obo/GO_0002228 natural killer cell mediated immunity The directed killing of a target cell by a natural killer cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors. http://purl.obolibrary.org/obo/GO_0042269 regulation of natural killer cell mediated cytotoxicity http://purl.obolibrary.org/obo/GO_0002715 regulation of natural killer cell mediated immunity Any process that modulates the frequency, rate, or extent of natural killer cell mediated cytotoxicity. http://purl.obolibrary.org/obo/CL_0000825 pro-NK cell http://purl.obolibrary.org/obo/CL_0000838 lymphoid lineage restricted progenitor cell A lymphoid progenitor cell that is committed to the natural killer cell lineage, expressing CD122 (IL-15) receptor, but lacking many of the phenotypic characteristics of later stages of natural killer cell development such as expression of NK activating and inhibitory molecules. In human this cell has the phenotype CD34-positive, CD45RA-positive, CD10-positive, CD117-negative, and CD161 negative. http://purl.obolibrary.org/obo/GO_0042277 peptide binding http://purl.obolibrary.org/obo/GO_0005488 binding Binding to a peptide, an organic compound comprising two or more amino acids linked by peptide bonds. http://purl.obolibrary.org/obo/CL_0000826 pro-B cell http://purl.obolibrary.org/obo/CL_0000838 lymphoid lineage restricted progenitor cell A progenitor cell of the B cell lineage, with some lineage specific activity such as early stages of recombination of B cell receptor genes, but not yet fully committed to the B cell lineage until the expression of PAX5 occurs. http://purl.obolibrary.org/obo/GO_0042330 taxis http://purl.obolibrary.org/obo/GO_0040011 locomotion The directed movement of a motile cell or organism in response to an external stimulus. http://purl.obolibrary.org/obo/GO_0042391 regulation of membrane potential http://purl.obolibrary.org/obo/GO_0065008 regulation of biological quality Any process that modulates the establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane. http://purl.obolibrary.org/obo/CL_0000827 pro-T cell http://purl.obolibrary.org/obo/CL_0000838 lymphoid lineage restricted progenitor cell A lymphoid progenitor cell of the T cell lineage, with some lineage specific marker expression, but not yet fully committed to the T cell lineage. http://purl.obolibrary.org/obo/CL_0000828 thromboblast http://purl.obolibrary.org/obo/CL_0000839 myeloid lineage restricted progenitor cell A progenitor cell of the thrombocyte, a nucleated blood cell involved in coagulation typically seen in birds and other non-mammalian vertebrates. http://purl.obolibrary.org/obo/GO_0042401 biogenic amine biosynthetic process http://purl.obolibrary.org/obo/GO_0009309 amine biosynthetic process The chemical reactions and pathways occurring at the level of individual cells resulting in the formation of any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters. http://purl.obolibrary.org/obo/CL_0000829 basophilic myeloblast http://purl.obolibrary.org/obo/CL_0000835 myeloblast A myeloblast committed to the basophil lineage. http://purl.obolibrary.org/obo/GO_0042402 biogenic amine catabolic process http://purl.obolibrary.org/obo/GO_0009310 amine catabolic process The chemical reactions and pathways occurring at the level of individual cells resulting in the breakdown of biogenic amines, any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters. http://purl.obolibrary.org/obo/CL_0000830 basophilic promyelocyte http://purl.obolibrary.org/obo/CL_0000836 promyelocyte A promyelocyte committed to the basophil lineage. http://purl.obolibrary.org/obo/CL_0000831 mast cell progenitor http://purl.obolibrary.org/obo/CL_0000839 myeloid lineage restricted progenitor cell A progenitor cell of the mast cell lineage. Markers for this cell are FceRIa-low, CD117-positive, CD9-positive, T1/ST2-positive, SCA1-negative, and lineage-negative. http://purl.obolibrary.org/obo/GO_0042419 epinephrine catabolic process http://purl.obolibrary.org/obo/GO_0042424 catecholamine catabolic process The chemical reactions and pathways resulting in the breakdown of epinephrine, a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine. http://purl.obolibrary.org/obo/CL_0000832 eosinophilic myeloblast http://purl.obolibrary.org/obo/CL_0000835 myeloblast A myeloblast committed to the eosinophil lineage. http://purl.obolibrary.org/obo/GO_0042472 inner ear morphogenesis http://purl.obolibrary.org/obo/GO_0048598 embryonic morphogenesis The process in which the anatomical structures of the inner ear are generated and organized. The inner ear is the structure in vertebrates that contains the organs of balance and hearing. It consists of soft hollow sensory structures (the membranous labyrinth) containing fluid (endolymph) surrounded by fluid (perilymph) and encased in a bony cavity (the bony labyrinth). It consists of two chambers, the sacculus and utriculus, from which arise the cochlea and semicircular canals respectively. http://purl.obolibrary.org/obo/CL_0000833 eosinophilic promyelocyte http://purl.obolibrary.org/obo/CL_0000836 promyelocyte A promyelocyte committed to the eosinophil lineage. http://purl.obolibrary.org/obo/CL_0000834 neutrophil progenitor cell http://purl.obolibrary.org/obo/CL_0002191 granulocytopoietic cell A progenitor cell of the neutrophil lineage. http://purl.obolibrary.org/obo/GO_0042492 gamma-delta T cell differentiation http://purl.obolibrary.org/obo/GO_0046629 gamma-delta T cell activation The process in which a relatively unspecialized hemopoietic cell acquires specialized features of a gamma-delta T cell. A gamma-delta T cell is a T cell that expresses a gamma-delta T cell receptor complex. http://purl.obolibrary.org/obo/CL_0000835 myeloblast http://purl.obolibrary.org/obo/CL_0002191 granulocytopoietic cell The most primitive precursor in the granulocytic series, having fine, evenly distributed chromatin, several nucleoli, a high nuclear-to-cytoplasmic ration (5:1-7:1), and a nongranular basophilic cytoplasm. They reside in the bone marrow. http://purl.obolibrary.org/obo/GO_0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I http://purl.obolibrary.org/obo/GO_0002478 antigen processing and presentation of exogenous peptide antigen The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class I protein complex. The peptide antigen is typically, but not always, processed from a whole protein. Class I here refers to classical class I molecules. http://purl.obolibrary.org/obo/CL_0000836 promyelocyte http://purl.obolibrary.org/obo/CL_0002191 granulocytopoietic cell A precursor in the granulocytic series, being a cell intermediate in development between a myeloblast and myelocyte, that has distinct nucleoli, a nuclear-to-cytoplasmic ratio of 5:1 to 3:1, and containing a few primary cytoplasmic granules. Markers for this cell are fucosyltransferase FUT4-positive, CD33-positive, integrin alpha-M-negative, low affinity immunoglobulin gamma Fc region receptor III-negative, and CD24-negative. http://purl.obolibrary.org/obo/GO_0042592 homeostatic process http://purl.obolibrary.org/obo/GO_0008150 biological_process Any biological process involved in the maintenance of an internal steady state. Homeostasis allows cells and organisms to maintain stable internal conditions despite varying external conditions. http://purl.obolibrary.org/obo/CL_0000837 hematopoietic multipotent progenitor cell http://purl.obolibrary.org/obo/CL_0008001 hematopoietic precursor cell A hematopoietic multipotent progenitor cell is multipotent, but not capable of long-term self-renewal. These cells are characterized as lacking lineage cell surface markers and being CD34-positive in both mice and humans. http://purl.obolibrary.org/obo/GO_0042593 glucose homeostasis http://purl.obolibrary.org/obo/GO_0033500 carbohydrate homeostasis Any process involved in the maintenance of an internal steady state of glucose within an organism or cell. http://purl.obolibrary.org/obo/CL_0000838 lymphoid lineage restricted progenitor cell http://purl.obolibrary.org/obo/CL_0011026 progenitor cell A progenitor cell restricted to the lymphoid lineage. http://purl.obolibrary.org/obo/GO_0042641 actomyosin http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure Any complex of actin, myosin, and accessory proteins. http://purl.obolibrary.org/obo/CL_0000839 myeloid lineage restricted progenitor cell http://purl.obolibrary.org/obo/CL_0011026 progenitor cell A progenitor cell restricted to the myeloid lineage. http://purl.obolibrary.org/obo/GO_0042645 mitochondrial nucleoid http://purl.obolibrary.org/obo/GO_0009295 nucleoid The region of a mitochondrion to which the DNA is confined. http://purl.obolibrary.org/obo/CL_0000840 immature conventional dendritic cell http://purl.obolibrary.org/obo/CL_0000990 conventional dendritic cell An immature cell of the conventional dendritic cell lineage, characterized by high levels of antigen uptake via endocytosis, macropinocytosis, and phagocytosis, and typically found resident in the tissues. Markers for this cell are CD80-low, CD86-low, and MHC-II-low. http://purl.obolibrary.org/obo/GO_0042981 regulation of apoptotic process http://purl.obolibrary.org/obo/GO_0043067 regulation of programmed cell death Any process that modulates the occurrence or rate of cell death by apoptotic process. http://purl.obolibrary.org/obo/GO_0042995 cell projection http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure A prolongation or process extending from a cell, e.g. a flagellum or axon. http://purl.obolibrary.org/obo/CL_0000841 mature conventional dendritic cell http://purl.obolibrary.org/obo/CL_0000990 conventional dendritic cell A mature cell of the conventional dendritic cell lineage, characterized by a high capacity for antigen presentation and typically found in a lymph node. http://purl.obolibrary.org/obo/CL_0000842 mononuclear leukocyte http://purl.obolibrary.org/obo/CL_0000738 leukocyte A leukocyte with a single non-segmented nucleus in the mature form. http://purl.obolibrary.org/obo/GO_0043009 chordate embryonic development http://purl.obolibrary.org/obo/GO_0009792 embryo development ending in birth or egg hatching The process whose specific outcome is the progression of the embryo over time, from zygote formation through a stage including a notochord and neural tube until birth or egg hatching. http://purl.obolibrary.org/obo/CL_0000843 follicular B cell http://purl.obolibrary.org/obo/CL_0000822 B-2 B cell A resting mature B cell that has the phenotype IgM-positive, IgD-positive, CD23-positive and CD21-positive, and found in the B cell follicles of the white pulp of the spleen or the corticol areas of the peripheral lymph nodes. This cell type is also described as being CD19-positive, B220-positive, AA4-negative, CD43-negative, and CD5-negative. http://purl.obolibrary.org/obo/GO_0043010 camera-type eye development http://purl.obolibrary.org/obo/GO_0001654 eye development The process whose specific outcome is the progression of the camera-type eye over time, from its formation to the mature structure. The camera-type eye is an organ of sight that receives light through an aperture and focuses it through a lens, projecting it on a photoreceptor field. http://purl.obolibrary.org/obo/CL_0000844 germinal center B cell http://purl.obolibrary.org/obo/CL_0000785 mature B cell A rapidly cycling mature B cell that has distinct phenotypic characteristics and is involved in T-dependent immune responses and located typically in the germinal centers of lymph nodes. This cell type expresses Ly77 after activation. http://purl.obolibrary.org/obo/GO_0043011 myeloid dendritic cell differentiation http://purl.obolibrary.org/obo/GO_0097028 dendritic cell differentiation The process in which a monocyte acquires the specialized features of a dendritic cell, an immunocompetent cell of the lymphoid and hemopoietic systems and skin. http://purl.obolibrary.org/obo/GO_0043029 T cell homeostasis http://purl.obolibrary.org/obo/GO_0002260 lymphocyte homeostasis The process of regulating the proliferation and elimination of T cells such that the total number of T cells within a whole or part of an organism is stable over time in the absence of an outside stimulus. http://purl.obolibrary.org/obo/CL_0000845 marginal zone B cell of spleen http://purl.obolibrary.org/obo/CL_2000074 splenocyte A mature B cell that is located in the marginal zone of the spleen with the phenotype CD23-negative and CD21-positive and expressing a B cell receptor usually reactive to bacterial cell wall components or senescent self components such as oxidized-LDL. This cell type is also described as being CD19-positive, B220-positive, IgM-high, AA4-negative, CD35-high. http://purl.obolibrary.org/obo/GO_0043043 peptide biosynthetic process http://purl.obolibrary.org/obo/GO_0009058 biosynthetic process The chemical reactions and pathways resulting in the formation of peptides, compounds of 2 or more (but usually less than 100) amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another. This may include the translation of a precursor protein and its subsequent processing into a functional peptide. http://purl.obolibrary.org/obo/CL_0000846 vestibular dark cell http://purl.obolibrary.org/obo/CL_0000066 epithelial cell An epithelial cell of the vestibular sensory organ that is characterized by intense enzymatic activities and numerous basal membrane infoldings. http://purl.obolibrary.org/obo/CL_0000847 ciliated olfactory receptor neuron http://purl.obolibrary.org/obo/CL_0000207 olfactory receptor cell An olfactory receptor cell in which the apical ending of the dendrite is a pronounced ciliated olfactory knob. http://purl.obolibrary.org/obo/GO_0043073 germ cell nucleus http://purl.obolibrary.org/obo/GO_0005634 nucleus The nucleus of a germ cell, a reproductive cell in multicellular organisms. http://purl.obolibrary.org/obo/CL_0000848 microvillous olfactory receptor neuron http://purl.obolibrary.org/obo/CL_0000207 olfactory receptor cell An olfactory receptor cell in which the apical ending of the dendrite is a knob that bears numerous microvilli. http://purl.obolibrary.org/obo/GO_0043083 synaptic cleft http://purl.obolibrary.org/obo/GO_0005576 extracellular region The narrow gap that separates the presynaptic and postsynaptic membranes, into which neurotransmitter is released. http://purl.obolibrary.org/obo/GO_0043114 regulation of vascular permeability http://purl.obolibrary.org/obo/GO_0065008 regulation of biological quality Any process that modulates the extent to which blood vessels can be pervaded by fluid. http://purl.obolibrary.org/obo/CL_0000849 crypt olfactory receptor neuron http://purl.obolibrary.org/obo/CL_0000207 olfactory receptor cell An olfactory receptor cell with short cilia growing in an invagination bordered by microvilli. http://purl.obolibrary.org/obo/CL_0000850 serotonergic neuron http://purl.obolibrary.org/obo/CL_0000540 neuron A neuron that releases serotonin as a neurotransmitter. http://purl.obolibrary.org/obo/GO_0043168 anion binding http://purl.obolibrary.org/obo/GO_0043167 ion binding Binding to an anion, a charged atom or group of atoms with a net negative charge. http://purl.obolibrary.org/obo/GO_0043171 peptide catabolic process http://purl.obolibrary.org/obo/GO_0009056 catabolic process The chemical reactions and pathways resulting in the breakdown of peptides, compounds of 2 or more (but usually less than 100) amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another. http://purl.obolibrary.org/obo/CL_0000851 neuromast mantle cell http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell Neuromast mantle cell is a non-sensory cell. Neuromast mantle cells surround the neuromast support cells and neuromast hair cells, separating the neuromast from the epidermis, and secrete cupula in which the ciliary bundles of all the hair cells are embedded. http://purl.obolibrary.org/obo/GO_0043178 alcohol binding http://purl.obolibrary.org/obo/GO_0036094 small molecule binding Binding to an alcohol, any of a class of alkyl compounds containing a hydroxyl group. http://purl.obolibrary.org/obo/CL_0000852 neuromast supporting cell http://purl.obolibrary.org/obo/CL_0000630 supporting cell Neuromast support cell is a non-sensory cell of the neuromast that extend between the sensory hair cells from the basement membrane to the apical surface; neuromast support cells are surrounded by neuromast mantle cells. http://purl.obolibrary.org/obo/GO_0043207 response to external biotic stimulus http://purl.obolibrary.org/obo/GO_0009607 response to biotic stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external biotic stimulus, an external stimulus caused by, or produced by living things. http://purl.obolibrary.org/obo/CL_0000853 olfactory epithelial supporting cell http://purl.obolibrary.org/obo/CL_0002167 olfactory epithelial cell Olfactory epithelial support cell is a columnar cell that extends from the epithelial free margin to the basement membrane of the olfactory epithelium. This cell type has a large, vertically, elongate, euchromatic nucleus, along with other nuclei, forms a layer superficial to the cell body of the receptor cell; sends long somewhat irregular microvilli into the mucus layer; at the base, with expanded end-feet containing numerous lamellated dense bodies resembling lipofuscin of neurons. http://purl.obolibrary.org/obo/GO_0043226 organelle http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane. http://purl.obolibrary.org/obo/GO_0043232 intracellular membraneless organelle http://purl.obolibrary.org/obo/GO_0043228 membraneless organelle Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes. http://purl.obolibrary.org/obo/CL_0000854 interneuromast cell http://purl.obolibrary.org/obo/CL_0000133 neurectodermal cell Interneuromast cell is a neuroectodermal cell deposited by the migrating lateral line primordium between the neuromasts. Interneuromast cells proliferate and migrate to form additional neuromasts. http://purl.obolibrary.org/obo/GO_0043235 receptor complex http://purl.obolibrary.org/obo/GO_0032991 protein-containing complex Any protein complex that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function. http://purl.obolibrary.org/obo/CL_0000855 sensory hair cell http://purl.obolibrary.org/obo/CL_0000199 mechanoreceptor cell Hair cell is a mechanoreceptor cell that is sensitive to movement of the hair-like projections (stereocilia and kinocilia) which relay the information centrally in the nervous system. http://purl.obolibrary.org/obo/GO_0043254 regulation of protein-containing complex assembly http://purl.obolibrary.org/obo/GO_0051128 regulation of cellular component organization Any process that modulates the frequency, rate or extent of protein complex assembly. http://purl.obolibrary.org/obo/CL_0000856 neuromast hair cell http://purl.obolibrary.org/obo/CL_0000855 sensory hair cell Neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. http://purl.obolibrary.org/obo/GO_0043299 leukocyte degranulation http://purl.obolibrary.org/obo/GO_0045055 regulated exocytosis The regulated exocytosis of secretory granules by a leukocyte. http://purl.obolibrary.org/obo/CL_0000857 slow muscle myoblast http://purl.obolibrary.org/obo/CL_0000515 skeletal muscle myoblast A skeletal muscle myoblast that differentiates into slow muscle fibers. http://purl.obolibrary.org/obo/GO_0043303 mast cell degranulation http://purl.obolibrary.org/obo/GO_0051656 establishment of organelle localization The regulated exocytosis of secretory granules containing preformed mediators such as histamine, serotonin, and neutral proteases by a mast cell. http://purl.obolibrary.org/obo/CL_0000858 fast muscle myoblast http://purl.obolibrary.org/obo/CL_0000515 skeletal muscle myoblast A skeletal muscle myoblast that differentiates into fast muscle fibers. http://purl.obolibrary.org/obo/GO_0043307 eosinophil activation http://purl.obolibrary.org/obo/GO_0036230 granulocyte activation The change in morphology and behavior of a eosinophil resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. http://purl.obolibrary.org/obo/CL_0000860 classical monocyte http://purl.obolibrary.org/obo/CL_0000576 monocyte A monocyte that responds rapidly to microbial stimuli by secreting cytokines and antimicrobial factors and which is characterized by high expression of CCR2 in both rodents and humans, negative for the lineage markers CD3, CD19, and CD20, and of larger size than non-classical monocytes. http://purl.obolibrary.org/obo/GO_0043367 CD4-positive, alpha-beta T cell differentiation http://purl.obolibrary.org/obo/GO_0035710 CD4-positive, alpha-beta T cell activation The process in which a relatively unspecialized T cell acquires specialized features of a mature CD4-positive, alpha-beta T cell. http://purl.obolibrary.org/obo/CL_0000861 elicited macrophage http://purl.obolibrary.org/obo/CL_0000235 macrophage A macrophage which develops from an inflammatory monocyte and is recruited into the tissues in response to injury and infection as part of an inflammatory response. Markers include CD11b-positive, CD68-positive, and F4/80-positive. http://purl.obolibrary.org/obo/GO_0043374 CD8-positive, alpha-beta T cell differentiation http://purl.obolibrary.org/obo/GO_0036037 CD8-positive, alpha-beta T cell activation The process in which a relatively unspecialized T cell acquires specialized features of a mature CD8-positive, alpha-beta T cell. http://purl.obolibrary.org/obo/CL_0000862 suppressor macrophage http://purl.obolibrary.org/obo/CL_0000861 elicited macrophage A macrophage that suppresses immune responses. http://purl.obolibrary.org/obo/GO_0043436 oxoacid metabolic process http://purl.obolibrary.org/obo/GO_0006082 organic acid metabolic process The chemical reactions and pathways involving any oxoacid; an oxoacid is a compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons). http://purl.obolibrary.org/obo/CL_0000863 M1 macrophage http://purl.obolibrary.org/obo/CL_0000861 elicited macrophage An elicited macrophage that is recruited into the tissues in response to injury and infection as part of an inflammatory response, expresses high levels of pro-inflammatory cytokines, ROS and NO, and shows potent microbicidal activity. http://purl.obolibrary.org/obo/GO_0043467 regulation of generation of precursor metabolites and energy http://purl.obolibrary.org/obo/GO_0019222 regulation of metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of precursor metabolites, substances from which energy is derived, and the processes involved in the liberation of energy from these substances. http://purl.obolibrary.org/obo/CL_0000864 tissue-resident macrophage http://purl.obolibrary.org/obo/CL_0000235 macrophage A macrophage constitutively resident in a particular tissue under non-inflammatory conditions, and capable of phagocytosing a variety of extracellular particulate material, including immune complexes, microorganisms, and dead cells. http://purl.obolibrary.org/obo/GO_0043500 muscle adaptation http://purl.obolibrary.org/obo/GO_0003012 muscle system process A process in which muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities. http://purl.obolibrary.org/obo/CL_0000865 gastrointestinal tract (lamina propria) macrophage http://purl.obolibrary.org/obo/CL_0000885 gut-associated lymphoid tissue macrophage A gut-associated lymphoid tissue macrophage found in lamina propria of the gut. http://purl.obolibrary.org/obo/CL_0000866 thymic macrophage http://purl.obolibrary.org/obo/CL_0000864 tissue-resident macrophage A tissue-resident macrophage resident found in the thymus, involved in the clearance of apoptotic thymocytes. http://purl.obolibrary.org/obo/GO_0043531 ADP binding http://purl.obolibrary.org/obo/GO_0043168 anion binding Binding to ADP, adenosine 5'-diphosphate. http://purl.obolibrary.org/obo/CL_0000867 secondary lymphoid organ macrophage http://purl.obolibrary.org/obo/CL_0000864 tissue-resident macrophage A tissue-resident macrophage found in a secondary lymphoid organ. http://purl.obolibrary.org/obo/GO_0043534 blood vessel endothelial cell migration http://purl.obolibrary.org/obo/GO_0043542 endothelial cell migration The orderly movement of an endothelial cell into the extracellular matrix in order to form new blood vessels during angiogenesis. http://purl.obolibrary.org/obo/CL_0000868 lymph node macrophage http://purl.obolibrary.org/obo/CL_0000867 secondary lymphoid organ macrophage A secondary lymphoid organ macrophage found in a lymph node. This cell is CD169-high. http://purl.obolibrary.org/obo/GO_0043933 protein-containing complex organization http://purl.obolibrary.org/obo/GO_0016043 cellular component organization Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein complex. http://purl.obolibrary.org/obo/CL_0000869 tonsillar macrophage http://purl.obolibrary.org/obo/CL_0000885 gut-associated lymphoid tissue macrophage A gut-associated lymphoid tissue macrophage found in tonsils. http://purl.obolibrary.org/obo/GO_0044065 regulation of respiratory system process http://purl.obolibrary.org/obo/GO_0043576 regulation of respiratory gaseous exchange Any process that modulates the frequency, rate or extent of a respiratory system process, an organ system process carried out by any of the organs or tissues of the respiratory system. http://purl.obolibrary.org/obo/CL_0000870 Peyer's patch macrophage http://purl.obolibrary.org/obo/CL_0000885 gut-associated lymphoid tissue macrophage A gut-associated lymphoid tissue macrophage found in the Peyer's patches. http://purl.obolibrary.org/obo/GO_0044272 sulfur compound biosynthetic process http://purl.obolibrary.org/obo/GO_0009058 biosynthetic process The chemical reactions and pathways resulting in the formation of compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione. http://purl.obolibrary.org/obo/CL_0000871 splenic macrophage http://purl.obolibrary.org/obo/CL_2000074 splenocyte A secondary lymphoid organ macrophage found in the spleen. http://purl.obolibrary.org/obo/CL_0000872 splenic marginal zone macrophage http://purl.obolibrary.org/obo/CL_0000871 splenic macrophage A splenic macrophage found in the marginal zone of the spleen, involved in recognition and clearance of particulate material from the splenic circulation. Markers include F4/80-negative, MARCO-positive, SR-A-positive, SIGN-R1-positive, and Dectin2-positive. http://purl.obolibrary.org/obo/GO_0044273 sulfur compound catabolic process http://purl.obolibrary.org/obo/GO_0009056 catabolic process The chemical reactions and pathways resulting in the breakdown of compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione. http://purl.obolibrary.org/obo/GO_0044282 small molecule catabolic process http://purl.obolibrary.org/obo/GO_0009056 catabolic process The chemical reactions and pathways resulting in the breakdown of small molecules, any low molecular weight, monomeric, non-encoded molecule. http://purl.obolibrary.org/obo/CL_0000873 splenic metallophillic macrophage http://purl.obolibrary.org/obo/CL_0000871 splenic macrophage A splenic macrophage found in the areas surrounding the white pulp of the spleen, adjacent to the marginal sinus. Markers include F4/80-negative, Dectin2-low, sialoadhesin-positive. http://purl.obolibrary.org/obo/GO_0044283 small molecule biosynthetic process http://purl.obolibrary.org/obo/GO_0009058 biosynthetic process The chemical reactions and pathways resulting in the formation of small molecules, any low molecular weight, monomeric, non-encoded molecule. http://purl.obolibrary.org/obo/CL_0000874 splenic red pulp macrophage http://purl.obolibrary.org/obo/CL_0000871 splenic macrophage A splenic macrophage found in the red-pulp of the spleen, and involved in immune responses to blood-borne pathogens and in the clearance of senescent erythrocytes. Markers include F4/80-positive, CD68-positive, MR-positive, Dectin2-positive, macrosialin-positive, and sialoadhesin-low. http://purl.obolibrary.org/obo/GO_0044703 multi-organism reproductive process http://purl.obolibrary.org/obo/GO_0022414 reproductive process A biological process that directly contributes to the process of producing new individuals, involving another organism. http://purl.obolibrary.org/obo/CL_0000875 non-classical monocyte http://purl.obolibrary.org/obo/CL_0000576 monocyte A type of monocyte characterized by low expression of CCR2, low responsiveness to monocyte chemoattractant CCL2/MCP1, low phagocytic activity, and decrease size relative to classical monocytes, but increased co-stimulatory activity. May also play a role in tissue repair. http://purl.obolibrary.org/obo/GO_0044848 biological phase http://purl.obolibrary.org/obo/GO_0008150 biological_process A distinct period or stage in a biological process or cycle. http://purl.obolibrary.org/obo/CL_0000876 splenic white pulp macrophage http://purl.obolibrary.org/obo/CL_0000871 splenic macrophage A splenic macrophage found in the white pulp of the spleen. Markers include F4/80-negative, CD68-positive, and macrosialin-positive. http://purl.obolibrary.org/obo/GO_0045026 plasma membrane fusion http://purl.obolibrary.org/obo/GO_0061025 membrane fusion The joining of the lipid bilayer membrane that surround a cell with that of another cell, producing a single cell. http://purl.obolibrary.org/obo/GO_0045028 G protein-coupled purinergic nucleotide receptor activity http://purl.obolibrary.org/obo/GO_0004930 G protein-coupled receptor activity Combining with a purine nucleotide and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. http://purl.obolibrary.org/obo/CL_0000877 splenic tingible body macrophage http://purl.obolibrary.org/obo/CL_0000876 splenic white pulp macrophage A splenic white pulp macrophage found in and around the germinal centers of the white pulp of the spleen that participates in phagocytosis of apoptotic B cells from the germinal centers. A marker for a cell of this type is Mertk-positive. http://purl.obolibrary.org/obo/GO_0045055 regulated exocytosis http://purl.obolibrary.org/obo/GO_0006887 exocytosis A process of exocytosis in which soluble proteins and other substances are initially stored in secretory vesicles for later release. It is found mainly in cells that are specialized for secreting products such as hormones, neurotransmitters, or digestive enzymes rapidly on demand. http://purl.obolibrary.org/obo/CL_0000878 central nervous system macrophage http://purl.obolibrary.org/obo/CL_0002319 neural cell A tissue-resident macrophage found in the central nervous system. http://purl.obolibrary.org/obo/CL_0000879 meningeal macrophage http://purl.obolibrary.org/obo/CL_4042003 border associated macrophage A border associated macrophage that is part of a meninx. This macrophage type is elongated and amoeboid spindle-shaped with limited mobility. This macrophage is highly phagocytic, expresses scavenger receptors, has dynamic protrusions and extends its processes during inflammation. http://purl.obolibrary.org/obo/GO_0045063 T-helper 1 cell differentiation http://purl.obolibrary.org/obo/GO_0042093 T-helper cell differentiation The process in which a relatively unspecialized T cell acquires the specialized features of a T-helper 1 (Th1) cell. A Th1 cell is a CD4-positive, alpha-beta T cell that has the phenotype T-bet-positive and produces interferon-gamma. http://purl.obolibrary.org/obo/CL_0000880 choroid plexus macrophage http://purl.obolibrary.org/obo/CL_4042003 border associated macrophage A border associated macrophage found at the interface between the blood and the cerebrospinal fluid in the brain. This central nervous system macrophage has a star-like shaped body and expresses scavenger receptors. http://purl.obolibrary.org/obo/GO_0045064 T-helper 2 cell differentiation http://purl.obolibrary.org/obo/GO_0042093 T-helper cell differentiation The process in which a relatively unspecialized T cell acquires specialized features of a T-helper 2 (Th2) cell. A Th2 cell is a CD4-positive, alpha-beta T cell that has the phenotype GATA-3-positive and produces interleukin-4. http://purl.obolibrary.org/obo/CL_0000881 perivascular macrophage http://purl.obolibrary.org/obo/CL_4042003 border associated macrophage A border associated macrophage that is adjacent to a small blood vessel of a brain. A perivascular macrophage expresses the markers CD14, CD16 and CD163. In homeostatic conditions, this central nervous system macrophage has a non-motile cell body with extending and retracting projections through the blood vessel wall. http://purl.obolibrary.org/obo/GO_0045065 cytotoxic T cell differentiation http://purl.obolibrary.org/obo/GO_0030217 T cell differentiation The process in which a relatively unspecialized T cell acquires specialized features of a cytotoxic T cell. http://purl.obolibrary.org/obo/CL_0000882 thymic medullary macrophage http://purl.obolibrary.org/obo/CL_0000866 thymic macrophage A thymic macrophage found in the thymic medulla. http://purl.obolibrary.org/obo/GO_0045066 regulatory T cell differentiation http://purl.obolibrary.org/obo/GO_0030217 T cell differentiation The process in which a relatively unspecialized T cell acquires specialized features of a regulatory T cell. Regulatory T cells control or suppress immune responses through a variety of mechanisms and subsets include the CD4+CD25+ cell type as well as certain CD8+ cell types. http://purl.obolibrary.org/obo/CL_0000883 thymic cortical macrophage http://purl.obolibrary.org/obo/CL_0000866 thymic macrophage A thymic macrophage found in the thymic cortex. http://purl.obolibrary.org/obo/GO_0045087 innate immune response http://purl.obolibrary.org/obo/GO_0140546 defense response to symbiont Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens. http://purl.obolibrary.org/obo/CL_0000884 mucosa-associated lymphoid tissue macrophage http://purl.obolibrary.org/obo/CL_0000867 secondary lymphoid organ macrophage A tissue-resident macrophage found in the mucosa associated lymphoid tissue. http://purl.obolibrary.org/obo/GO_0045088 regulation of innate immune response http://purl.obolibrary.org/obo/GO_0031347 regulation of defense response Any process that modulates the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection. http://purl.obolibrary.org/obo/CL_0000885 gut-associated lymphoid tissue macrophage http://purl.obolibrary.org/obo/CL_0000884 mucosa-associated lymphoid tissue macrophage A mucosa-associated lymphoid tissue macrophage found in the mucosa-associated lymphoid tissues of the gut. http://purl.obolibrary.org/obo/GO_0045089 positive regulation of innate immune response http://purl.obolibrary.org/obo/GO_0050778 positive regulation of immune response Any process that activates or increases the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection. http://purl.obolibrary.org/obo/CL_0000886 nasal and broncial associated lymphoid tissue macrophage http://purl.obolibrary.org/obo/CL_0000884 mucosa-associated lymphoid tissue macrophage A mucosa-associated lymphoid tissue macrophage found in the nasal and bronchial mucosa-associated lymphoid tissues. http://purl.obolibrary.org/obo/GO_0045120 pronucleus http://purl.obolibrary.org/obo/GO_0005634 nucleus The nucleus of either the ovum or the spermatozoon following fertilization. Thus, in the fertilized ovum, there are two pronuclei, one originating from the ovum, the other from the spermatozoon that brought about fertilization; they approach each other, but do not fuse until just before the first cleavage, when each pronucleus loses its membrane to release its contents. http://purl.obolibrary.org/obo/CL_0000887 lymph node subcapsular sinus macrophage http://purl.obolibrary.org/obo/CL_0000868 lymph node macrophage A lymph node macrophage found in the subcapsular sinus of lymph nodes that participates in sensing, clearance, and antigen presentation of lymph-borne particulate antigens. This macrophage is capable of activating invaraint NKT cells and is CD169-positive. http://purl.obolibrary.org/obo/GO_0045165 cell fate commitment http://purl.obolibrary.org/obo/GO_0048869 cellular developmental process The cellular developmental process by which a cell establishes the intrinsic character of a cell or tissue region irreversibly committing it to a particular fate. http://purl.obolibrary.org/obo/CL_0000888 lymph node tingible body macrophage http://purl.obolibrary.org/obo/CL_0000868 lymph node macrophage A lymph node macrophage found in the cortex of lymph nodes, in particular in and around the germinal centers, and that participates in phagocytosis of apoptotic B cells from the germinal centers. http://purl.obolibrary.org/obo/GO_0045216 cell-cell junction organization http://purl.obolibrary.org/obo/GO_0034330 cell junction organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell-cell junction. A cell-cell junction is a specialized region of connection between two cells. http://purl.obolibrary.org/obo/CL_0000889 myeloid suppressor cell http://purl.obolibrary.org/obo/CL_0000766 myeloid leukocyte An immature myeloid leukocyte of heterogeneous phenotype found particularly in cancer and sepsis patients that is capable of suppressing activity of T cells in ex vivo assays. This cell type is CD45-positive, CD11b-positive. http://purl.obolibrary.org/obo/GO_0045321 leukocyte activation http://purl.obolibrary.org/obo/GO_0002376 immune system process A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor. http://purl.obolibrary.org/obo/CL_0000890 M2 macrophage http://purl.obolibrary.org/obo/CL_0000861 elicited macrophage An elicited macrophage characterized by low production of pro-inflammatory and Th1 polarizing cytokines and high expression of arginase-1, and associated with tissue remodelling. http://purl.obolibrary.org/obo/GO_0045446 endothelial cell differentiation http://purl.obolibrary.org/obo/GO_0030855 epithelial cell differentiation The process in which a mesodermal, bone marrow or neural crest cell acquires specialized features of an endothelial cell, a thin flattened cell. A layer of such cells lines the inside surfaces of body cavities, blood vessels, and lymph vessels, making up the endothelium. http://purl.obolibrary.org/obo/CL_0000891 foam cell http://purl.obolibrary.org/obo/CL_0000000 cell A type of cell containing lipids in small vacuoles and typically seen in atherolosclerotic lesions, as well as other conditions. http://purl.obolibrary.org/obo/GO_0045575 basophil activation http://purl.obolibrary.org/obo/GO_0036230 granulocyte activation The change in morphology and behavior of a basophil resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the basophil has specifically bound via IgE bound to Fc-epsilonRI receptors. http://purl.obolibrary.org/obo/CL_0000892 smooth muscle cell derived foam cell http://purl.obolibrary.org/obo/CL_0000891 foam cell A type of foam cell derived from a smooth muscle cell containing lipids in small vacuoles and typically seen in atherolosclerotic lesions, as well as other conditions. http://purl.obolibrary.org/obo/GO_0045576 mast cell activation http://purl.obolibrary.org/obo/GO_0002274 myeloid leukocyte activation The change in morphology and behavior of a mast cell resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the mast cell has specifically bound via IgE bound to Fc-epsilonRI receptors. http://purl.obolibrary.org/obo/CL_0000893 thymocyte http://purl.obolibrary.org/obo/CL_0002420 immature T cell An immature T cell located in the thymus. http://purl.obolibrary.org/obo/GO_0045577 regulation of B cell differentiation http://purl.obolibrary.org/obo/GO_0050864 regulation of B cell activation Any process that modulates the frequency, rate or extent of B cell differentiation. http://purl.obolibrary.org/obo/CL_0000894 DN1 thymic pro-T cell http://purl.obolibrary.org/obo/CL_0000827 pro-T cell A pro-T cell that has the phenotype CD4-negative, CD8-negative, CD44-positive, and CD25-negative. http://purl.obolibrary.org/obo/GO_0045578 negative regulation of B cell differentiation http://purl.obolibrary.org/obo/GO_0050869 negative regulation of B cell activation Any process that stops, prevents, or reduces the frequency, rate or extent of B cell differentiation. http://purl.obolibrary.org/obo/CL_0000895 naive thymus-derived CD4-positive, alpha-beta T cell http://purl.obolibrary.org/obo/CL_0000898 naive T cell An antigen inexperienced CD4-positive, alpha-beta T cell with the phenotype CCR7-positive, CD127-positive and CD62L-positive. This cell type develops in the thymus. This cell type is also described as being CD25-negative, CD62L-high, and CD44-low. http://purl.obolibrary.org/obo/GO_0045579 positive regulation of B cell differentiation http://purl.obolibrary.org/obo/GO_0050871 positive regulation of B cell activation Any process that activates or increases the frequency, rate or extent of B cell differentiation. http://purl.obolibrary.org/obo/GO_0045637 regulation of myeloid cell differentiation http://purl.obolibrary.org/obo/GO_1903706 regulation of hemopoiesis Any process that modulates the frequency, rate or extent of myeloid cell differentiation. http://purl.obolibrary.org/obo/CL_0000896 activated CD4-positive, alpha-beta T cell http://purl.obolibrary.org/obo/CL_0000624 CD4-positive, alpha-beta T cell A recently activated CD4-positive, alpha-beta T cell with the phenotype CD69-positive, CD62L-negative, CD127-negative, and CD25-positive. http://purl.obolibrary.org/obo/GO_0045638 negative regulation of myeloid cell differentiation http://purl.obolibrary.org/obo/GO_0045637 regulation of myeloid cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of myeloid cell differentiation. http://purl.obolibrary.org/obo/CL_0000897 CD4-positive, alpha-beta memory T cell http://purl.obolibrary.org/obo/CL_0000813 memory T cell A CD4-positive, alpha-beta T cell that has differentiated into a memory T cell. http://purl.obolibrary.org/obo/GO_0045639 positive regulation of myeloid cell differentiation http://purl.obolibrary.org/obo/GO_0045597 positive regulation of cell differentiation Any process that activates or increases the frequency, rate or extent of myeloid cell differentiation. http://purl.obolibrary.org/obo/CL_0000898 naive T cell http://purl.obolibrary.org/obo/CL_0002419 mature T cell Mature T cell not yet exposed to antigen with the phenotype CCR7-positive, CD45RA-positive, and CD127-positive. This cell type is also described as being CD25-negative, CD62L-high and CD44-low. http://purl.obolibrary.org/obo/GO_0045730 respiratory burst http://purl.obolibrary.org/obo/GO_0008152 metabolic process A phase of elevated metabolic activity, during which oxygen consumption increases; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals. http://purl.obolibrary.org/obo/CL_0000899 T-helper 17 cell http://purl.obolibrary.org/obo/CL_0000492 CD4-positive helper T cell CD4-positive, alpha-beta T cell with the phenotype RORgamma-t-positive, CXCR3-negative, CCR6-positive, and capable of producing IL-17. http://purl.obolibrary.org/obo/GO_0045744 negative regulation of G protein-coupled receptor signaling pathway http://purl.obolibrary.org/obo/GO_0008277 regulation of G protein-coupled receptor signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of G protein-coupled receptor signaling pathway. http://purl.obolibrary.org/obo/CL_0000900 naive thymus-derived CD8-positive, alpha-beta T cell http://purl.obolibrary.org/obo/CL_0000898 naive T cell A CD8-positive, alpha-beta T cell that has not experienced activation via antigen contact and has the phenotype CD45RA-positive, CCR7-positive and CD127-positive. This cell type is also described as being CD25-negative, CD62L-high and CD44-low. http://purl.obolibrary.org/obo/GO_0045786 negative regulation of cell cycle http://purl.obolibrary.org/obo/GO_0051726 regulation of cell cycle Any process that stops, prevents or reduces the rate or extent of progression through the cell cycle. http://purl.obolibrary.org/obo/CL_0000901 Tr1 cell http://purl.obolibrary.org/obo/CL_0000815 regulatory T cell CD4-positive alpha-beta T cell with regulatory function that produces IL-10. http://purl.obolibrary.org/obo/GO_0045822 negative regulation of heart contraction http://purl.obolibrary.org/obo/GO_0008016 regulation of heart contraction Any process that stops, prevents, or reduces the frequency, rate or extent of heart contraction. http://purl.obolibrary.org/obo/CL_0000902 induced T-regulatory cell http://purl.obolibrary.org/obo/CL_0000792 CD4-positive, CD25-positive, alpha-beta regulatory T cell CD4-positive alpha-beta T cell with the phenotype CD25-positive, CTLA-4-positive, and FoxP3-positive with regulatory function. http://purl.obolibrary.org/obo/GO_0045823 positive regulation of heart contraction http://purl.obolibrary.org/obo/GO_0008016 regulation of heart contraction Any process that activates or increases the frequency, rate or extent of heart contraction. http://purl.obolibrary.org/obo/CL_0000903 natural T-regulatory cell http://purl.obolibrary.org/obo/CL_0000792 CD4-positive, CD25-positive, alpha-beta regulatory T cell CD4-positive alpha-beta T cell with the phenotype FoxP3-positive, CD25-positive, CD62L-positive, and CTLA-4 positive with regulatory function. http://purl.obolibrary.org/obo/GO_0045824 negative regulation of innate immune response http://purl.obolibrary.org/obo/GO_0032102 negative regulation of response to external stimulus Any process that stops, prevents, or reduces the frequency, rate or extent of the innate immune response. http://purl.obolibrary.org/obo/CL_0000904 central memory CD4-positive, alpha-beta T cell http://purl.obolibrary.org/obo/CL_0001204 CD4-positive, alpha-beta memory T cell, CD45RO-positive CD4-positive, alpha-beta memory T cell with the phenotype CCR7-positive, CD127-positive, CD45RA-negative, CD45RO-positive, and CD25-negative. http://purl.obolibrary.org/obo/GO_0045839 negative regulation of mitotic nuclear division http://purl.obolibrary.org/obo/GO_0010948 negative regulation of cell cycle process Any process that stops, prevents or reduces the rate or extent of mitosis. Mitosis is the division of the eukaryotic cell nucleus to produce two daughter nuclei that, usually, contain the identical chromosome complement to their mother. http://purl.obolibrary.org/obo/CL_0000905 effector memory CD4-positive, alpha-beta T cell http://purl.obolibrary.org/obo/CL_0001204 CD4-positive, alpha-beta memory T cell, CD45RO-positive CD4-positive, alpha-beta memory T cell with the phenotype CCR7-negative, CD127-positive, CD45RA-negative, CD45RO-positive, and CD25-negative. http://purl.obolibrary.org/obo/GO_0045910 negative regulation of DNA recombination http://purl.obolibrary.org/obo/GO_0000018 regulation of DNA recombination Any process that stops, prevents, or reduces the frequency, rate or extent of DNA recombination. http://purl.obolibrary.org/obo/CL_0000906 activated CD8-positive, alpha-beta T cell http://purl.obolibrary.org/obo/CL_0000625 CD8-positive, alpha-beta T cell A CD8-positive, alpha-beta T cell with the phenotype CD69-positive, CD62L-negative, CD127-negative, CD25-positive, and CCR7-negative. http://purl.obolibrary.org/obo/GO_0045911 positive regulation of DNA recombination http://purl.obolibrary.org/obo/GO_0051054 positive regulation of DNA metabolic process Any process that activates or increases the frequency, rate or extent of DNA recombination. http://purl.obolibrary.org/obo/CL_0000907 central memory CD8-positive, alpha-beta T cell http://purl.obolibrary.org/obo/CL_0001203 CD8-positive, alpha-beta memory T cell, CD45RO-positive CD8-positive, alpha-beta memory T cell with the phenotype CCR7-positive, CD127-positive, CD45RA-negative, CD45RO-positive, and CD25-negative. http://purl.obolibrary.org/obo/GO_0045920 negative regulation of exocytosis http://purl.obolibrary.org/obo/GO_1903531 negative regulation of secretion by cell Any process that stops, prevents, or reduces the frequency, rate or extent of exocytosis. http://purl.obolibrary.org/obo/CL_0000908 CD8-positive, alpha-beta cytokine secreting effector T cell http://purl.obolibrary.org/obo/CL_0000625 CD8-positive, alpha-beta T cell A CD8-positive, alpha-beta T cell with the phenotype CD69-positive, CD62L-negative, CD127-negative, and CD25-positive, that secretes cytokines. http://purl.obolibrary.org/obo/GO_0045921 positive regulation of exocytosis http://purl.obolibrary.org/obo/GO_1903532 positive regulation of secretion by cell Any process that activates or increases the frequency, rate or extent of exocytosis. http://purl.obolibrary.org/obo/CL_0000909 CD8-positive, alpha-beta memory T cell http://purl.obolibrary.org/obo/CL_0000813 memory T cell A CD8-positive, alpha-beta T cell that has differentiated into a memory T cell. http://purl.obolibrary.org/obo/GO_0045953 negative regulation of natural killer cell mediated cytotoxicity http://purl.obolibrary.org/obo/GO_0042269 regulation of natural killer cell mediated cytotoxicity Any process that stops, prevents, or reduces the rate of natural killer mediated cytotoxicity. http://purl.obolibrary.org/obo/CL_0000910 cytotoxic T cell http://purl.obolibrary.org/obo/CL_0000911 effector T cell A mature T cell that differentiated and acquired cytotoxic function with the phenotype perforin-positive and granzyme-B positive. http://purl.obolibrary.org/obo/GO_0045954 positive regulation of natural killer cell mediated cytotoxicity http://purl.obolibrary.org/obo/GO_0042269 regulation of natural killer cell mediated cytotoxicity Any process that activates or increases the frequency, rate or extent of natural killer cell mediated cytotoxicity. http://purl.obolibrary.org/obo/CL_0000911 effector T cell http://purl.obolibrary.org/obo/CL_0002419 mature T cell A differentiated T cell with ability to traffic to peripheral tissues and is capable of mounting a specific immune response. http://purl.obolibrary.org/obo/GO_0045995 regulation of embryonic development http://purl.obolibrary.org/obo/GO_2000026 regulation of multicellular organismal development Any process that modulates the frequency, rate or extent of embryonic development. http://purl.obolibrary.org/obo/CL_0000912 helper T cell http://purl.obolibrary.org/obo/CL_0000911 effector T cell A effector T cell that provides help in the form of secreted cytokines to other immune cells. http://purl.obolibrary.org/obo/GO_0046165 alcohol biosynthetic process http://purl.obolibrary.org/obo/GO_0044283 small molecule biosynthetic process The chemical reactions and pathways resulting in the formation of alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom. http://purl.obolibrary.org/obo/CL_0000913 effector memory CD8-positive, alpha-beta T cell http://purl.obolibrary.org/obo/CL_0001203 CD8-positive, alpha-beta memory T cell, CD45RO-positive CD8-positive, alpha-beta memory T cell with the phenotype CCR7-negative, CD127-positive, CD45RA-negative, CD45RO-positive, and CD25-negative. http://purl.obolibrary.org/obo/GO_0046394 carboxylic acid biosynthetic process http://purl.obolibrary.org/obo/GO_0016053 organic acid biosynthetic process The chemical reactions and pathways resulting in the formation of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups. http://purl.obolibrary.org/obo/CL_0000914 immature NK T cell http://purl.obolibrary.org/obo/CL_0000790 immature alpha-beta T cell An immature alpha-beta T-cell that express Egr2. These cells give rise to T cells expressing NK markers. http://purl.obolibrary.org/obo/GO_0046530 photoreceptor cell differentiation http://purl.obolibrary.org/obo/GO_0030182 neuron differentiation The specialization of organization of a photoreceptor, a cell that responds to incident electromagnetic radiation, particularly visible light. An example of this process is found in Drosophila melanogaster. http://purl.obolibrary.org/obo/CL_0000915 CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell http://purl.obolibrary.org/obo/CL_0000797 alpha-beta intraepithelial T cell An alpha-beta intraepithelial T cell with the phenotype CD8-alpha-alpha-positive located in the columnar epithelium of the gastrointestinal tract. These cells have a memory phenotype of CD2-negative and CD5-negative. http://purl.obolibrary.org/obo/GO_0046620 regulation of organ growth http://purl.obolibrary.org/obo/GO_0048638 regulation of developmental growth Any process that modulates the frequency, rate or extent of growth of an organ of an organism. http://purl.obolibrary.org/obo/CL_0000916 dendritic epidermal T cell http://purl.obolibrary.org/obo/CL_0000800 mature gamma-delta T cell A mature gamma-delta T cell located in the epidermis that regulates wound healing. http://purl.obolibrary.org/obo/GO_0046629 gamma-delta T cell activation http://purl.obolibrary.org/obo/GO_0042110 T cell activation The change in morphology and behavior of a gamma-delta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. http://purl.obolibrary.org/obo/CL_0000917 Tc1 cell http://purl.obolibrary.org/obo/CL_0000908 CD8-positive, alpha-beta cytokine secreting effector T cell A CD8-positive, alpha-beta positive T cell that has the phenotype T-bet-positive, eomesodermin-positive, CXCR3-positive, CCR6-negative, and is capable of producing interferon-gamma. http://purl.obolibrary.org/obo/GO_0046630 gamma-delta T cell proliferation http://purl.obolibrary.org/obo/GO_0046629 gamma-delta T cell activation The expansion of a gamma-delta T cell population by cell division. http://purl.obolibrary.org/obo/CL_0000918 Tc2 cell http://purl.obolibrary.org/obo/CL_0001052 CD8-positive, CXCR3-negative, CCR6-negative, alpha-beta T cell A CD8-positive, alpha-beta positive T cell expressing GATA-3 and secreting IL-4. http://purl.obolibrary.org/obo/GO_0046631 alpha-beta T cell activation http://purl.obolibrary.org/obo/GO_0042110 T cell activation The change in morphology and behavior of an alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. http://purl.obolibrary.org/obo/CL_0000919 CD8-positive, CD25-positive, alpha-beta regulatory T cell http://purl.obolibrary.org/obo/CL_0000795 CD8-positive, alpha-beta regulatory T cell A CD8-positive alpha beta-positive T cell with the phenotype FoxP3-positive and having suppressor function. http://purl.obolibrary.org/obo/GO_0046632 alpha-beta T cell differentiation http://purl.obolibrary.org/obo/GO_0046631 alpha-beta T cell activation The process in which a precursor cell type acquires the specialized features of an alpha-beta T cell. An alpha-beta T cell is a T cell that expresses an alpha-beta T cell receptor complex. http://purl.obolibrary.org/obo/CL_0000920 CD8-positive, CD28-negative, alpha-beta regulatory T cell http://purl.obolibrary.org/obo/CL_0000795 CD8-positive, alpha-beta regulatory T cell CD8-positive, alpha-beta positive regulatory T cell with the phenotype CD28-negative and FoxP3-positive. http://purl.obolibrary.org/obo/GO_0046633 alpha-beta T cell proliferation http://purl.obolibrary.org/obo/GO_0046631 alpha-beta T cell activation The expansion of an alpha-beta T cell population by cell division. http://purl.obolibrary.org/obo/CL_0000921 type I NK T cell http://purl.obolibrary.org/obo/CL_0000814 mature NK T cell An alpha-beta T cell expressing NK cell markers that is CD1d restricted and expresses specific V-alpha chains. NK T cells of this type recognize the glycolipid alpha-galactosylceramide in the context of CD1d. http://purl.obolibrary.org/obo/GO_0046649 lymphocyte activation http://purl.obolibrary.org/obo/GO_0045321 leukocyte activation A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor. http://purl.obolibrary.org/obo/CL_0000922 type II NK T cell http://purl.obolibrary.org/obo/CL_0000814 mature NK T cell An alpha-beta T cell expressing NK call markers that is CD1d restricted and expresses a diverse TCR repertoire. Type II NKT cells do not become activated by alpha-galactosylceramide when presented by CD1d. http://purl.obolibrary.org/obo/GO_0046651 lymphocyte proliferation http://purl.obolibrary.org/obo/GO_0032943 mononuclear cell proliferation The expansion of a lymphocyte population by cell division. http://purl.obolibrary.org/obo/CL_0000923 CD4-positive type I NK T cell http://purl.obolibrary.org/obo/CL_0000921 type I NK T cell A type I NK T cell that has the phenotype CD4-positive. http://purl.obolibrary.org/obo/GO_0046661 male sex differentiation http://purl.obolibrary.org/obo/GO_0007548 sex differentiation The establishment of the sex of a male organism by physical differentiation. http://purl.obolibrary.org/obo/CL_0000924 CD4-negative, CD8-negative type I NK T cell http://purl.obolibrary.org/obo/CL_0000921 type I NK T cell A type I NK T cell that has the phenotype CD4-negative and CD8-negative. http://purl.obolibrary.org/obo/GO_0046717 acid secretion http://purl.obolibrary.org/obo/GO_0046903 secretion The controlled release of acid by a cell or a tissue. http://purl.obolibrary.org/obo/CL_0000925 activated CD4-positive type I NK T cell http://purl.obolibrary.org/obo/CL_0000923 CD4-positive type I NK T cell A type I NK T cell that has been recently activated, secretes interferon-gamma and IL-4, and has the phenotype CD4-positive, CD69-positive, and downregulated NK markers. http://purl.obolibrary.org/obo/GO_0046872 metal ion binding http://purl.obolibrary.org/obo/GO_0043169 cation binding Binding to a metal ion. http://purl.obolibrary.org/obo/CL_0000926 CD4-positive type I NK T cell secreting interferon-gamma http://purl.obolibrary.org/obo/CL_0000923 CD4-positive type I NK T cell A mature NK T cell that secretes interferon-gamma and enhances type 1 immune responses. http://purl.obolibrary.org/obo/GO_0046879 hormone secretion http://purl.obolibrary.org/obo/GO_0023061 signal release The regulated release of hormones, substances with a specific regulatory effect on a particular organ or group of cells. http://purl.obolibrary.org/obo/CL_0000927 CD4-positive type I NK T cell secreting interleukin-4 http://purl.obolibrary.org/obo/CL_0000923 CD4-positive type I NK T cell A mature NK T cell that predominantly secretes type 2 cytokines such as interleukin-4 and interleukin-13 and enhances type 2 immune responses. http://purl.obolibrary.org/obo/GO_0046903 secretion http://purl.obolibrary.org/obo/GO_0006810 transport The controlled release of a substance by a cell or a tissue. http://purl.obolibrary.org/obo/CL_0000928 activated CD4-negative, CD8-negative type I NK T cell http://purl.obolibrary.org/obo/CL_0000924 CD4-negative, CD8-negative type I NK T cell A type I NK T cell that has been recently activated, secretes interferon-gamma and interleukin-4, and has phenotype CD4-negative, CD8-negative, CD69-positive, and downregulated NK markers. http://purl.obolibrary.org/obo/GO_0046928 regulation of neurotransmitter secretion http://purl.obolibrary.org/obo/GO_0050804 modulation of chemical synaptic transmission Any process that modulates the frequency, rate or extent of the regulated release of a neurotransmitter from a cell. http://purl.obolibrary.org/obo/CL_0000929 CD4-negative, CD8-negative type I NK T cell secreting interferon-gamma http://purl.obolibrary.org/obo/CL_0000924 CD4-negative, CD8-negative type I NK T cell A mature NK T cell that secretes interferon-gamma and enhances Th1 immune responses. http://purl.obolibrary.org/obo/GO_0048002 antigen processing and presentation of peptide antigen http://purl.obolibrary.org/obo/GO_0019882 antigen processing and presentation The process in which an antigen-presenting cell expresses peptide antigen in association with an MHC protein complex on its cell surface, including proteolysis and transport steps for the peptide antigen both prior to and following assembly with the MHC protein complex. The peptide antigen is typically, but not always, processed from an endogenous or exogenous protein. http://purl.obolibrary.org/obo/CL_0000930 CD4-negative, CD8-negative type I NK T cell secreting interleukin-4 http://purl.obolibrary.org/obo/CL_0000924 CD4-negative, CD8-negative type I NK T cell A mature NK T cell that secretes interleukin-4 and enhances Th2 immune responses. http://purl.obolibrary.org/obo/GO_0048143 astrocyte activation http://purl.obolibrary.org/obo/GO_0061900 glial cell activation A change in morphology and behavior of an astrocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. http://purl.obolibrary.org/obo/CL_0000931 activated type II NK T cell http://purl.obolibrary.org/obo/CL_0000922 type II NK T cell A type II NK T cell that has been recently activated, secretes interferon-gamma and interleukin-4, and has the phenotype CD69-positive and downregulated NK markers. http://purl.obolibrary.org/obo/GO_0048162 multi-layer follicle stage http://purl.obolibrary.org/obo/GO_0022605 mammalian oogenesis stage The stage in oogenesis when many layers of follicle cells surround the oocyte. There is a yolk nucleus (Balbiani's Body) near the germinal vesicle. http://purl.obolibrary.org/obo/CL_0000932 type II NK T cell secreting interferon-gamma http://purl.obolibrary.org/obo/CL_0000922 type II NK T cell A type II NK T cell that has been recently activated, secretes interferon-gamma, and has the phenotype CD69-positive and downregulated NK markers. http://purl.obolibrary.org/obo/GO_0048165 fused antrum stage http://purl.obolibrary.org/obo/GO_0022605 mammalian oogenesis stage The stage in oogenesis when the antral spaces fuse to form a single antral space. The oocyte is suspended in the cumulus oophorous and the first polar body in the perivitelline space. http://purl.obolibrary.org/obo/CL_0000933 type II NK T cell secreting interleukin-4 http://purl.obolibrary.org/obo/CL_0000922 type II NK T cell A type II NK T cell that has been recently activated, secretes interleukin-4, and has the phenotype CD69-positive and downregulated NK markers. http://purl.obolibrary.org/obo/CL_0000934 CD4-positive, alpha-beta cytotoxic T cell http://purl.obolibrary.org/obo/CL_0000624 CD4-positive, alpha-beta T cell A CD4-positive, alpha-beta T cell that has cytotoxic function. http://purl.obolibrary.org/obo/GO_0048209 regulation of vesicle targeting, to, from or within Golgi http://purl.obolibrary.org/obo/GO_0060341 regulation of cellular localization Any process that modulates the frequency, rate, or destination of vesicle-mediated transport to, from or within the Golgi apparatus. http://purl.obolibrary.org/obo/CL_0000935 CD4-negative, CD8-negative, alpha-beta intraepithelial T cell http://purl.obolibrary.org/obo/CL_0000797 alpha-beta intraepithelial T cell A CD4-negative, CD8-negative, alpha-beta intraepithelial T cell that is found in the columnar epithelium of the gastrointestinal tract. http://purl.obolibrary.org/obo/GO_0048247 lymphocyte chemotaxis http://purl.obolibrary.org/obo/GO_0030595 leukocyte chemotaxis The directed movement of a lymphocyte in response to an external stimulus. http://purl.obolibrary.org/obo/CL_0000936 early lymphoid progenitor http://purl.obolibrary.org/obo/CL_0011026 progenitor cell A lymphoid progenitor cell that is found in bone marrow, gives rise to B cells, T cells, natural killer cells and dendritic cells, and has the phenotype Lin-negative, Kit-positive, Sca-1-positive, FLT3-positive, CD34-positive, CD150 negative, and GlyA-negative. http://purl.obolibrary.org/obo/GO_0048284 organelle fusion http://purl.obolibrary.org/obo/GO_0006996 organelle organization The creation of a single organelle from two or more organelles. http://purl.obolibrary.org/obo/CL_0000937 pre-natural killer cell http://purl.obolibrary.org/obo/CL_0000623 natural killer cell Cell committed to natural killer cell lineage that has the phenotype CD122-positive, CD34-positive, and CD117-positive. This cell type lacks expression of natural killer receptor proteins. http://purl.obolibrary.org/obo/GO_0048285 organelle fission http://purl.obolibrary.org/obo/GO_0006996 organelle organization The creation of two or more organelles by division of one organelle. http://purl.obolibrary.org/obo/CL_0000938 CD16-negative, CD56-bright natural killer cell, human http://purl.obolibrary.org/obo/CL_0000824 mature natural killer cell NK cell that has the phenotype CD56-bright, CD16-negative, and CD84-positive with the function to secrete interferon-gamma but is not cytotoxic. http://purl.obolibrary.org/obo/GO_0048308 organelle inheritance http://purl.obolibrary.org/obo/GO_0006996 organelle organization The partitioning of organelles between daughter cells at cell division. http://purl.obolibrary.org/obo/CL_0000939 CD16-positive, CD56-dim natural killer cell, human http://purl.obolibrary.org/obo/CL_0000824 mature natural killer cell A mature natural killer cell that has the phenotype CD56-low, CD16-positive and which is capable of cytotoxicity and cytokine production. http://purl.obolibrary.org/obo/GO_0048311 mitochondrion distribution http://purl.obolibrary.org/obo/GO_0051646 mitochondrion localization Any process that establishes the spatial arrangement of mitochondria between and within cells. http://purl.obolibrary.org/obo/CL_0000940 mucosal-associated invariant T cell http://purl.obolibrary.org/obo/CL_0000791 mature alpha-beta T cell An alpha-beta T cell that is found in the lamina propria of mucosal tissues and is restricted by the MR-1 molecule. This cell develops from double-positive, alpha-beta thymocyte. http://purl.obolibrary.org/obo/GO_0048332 mesoderm morphogenesis http://purl.obolibrary.org/obo/GO_0048729 tissue morphogenesis The process in which the anatomical structures of the mesoderm are generated and organized. http://purl.obolibrary.org/obo/CL_0000942 thymic plasmacytoid dendritic cell http://purl.obolibrary.org/obo/CL_0000784 plasmacytoid dendritic cell A plasmacytoid dendritic cell developing in the thymus with phenotype CD11c-negative or low, CD45RA-positive, CD11b-negative, and CD123-positive. http://purl.obolibrary.org/obo/GO_0048333 mesodermal cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a mesoderm cell. http://purl.obolibrary.org/obo/CL_0000943 Be1 Cell http://purl.obolibrary.org/obo/CL_0000968 Be cell A Be cell that facilitates development of T-helper 1 (Th1) phenotype in CD4-positive T cells, and secretes high levels of interleukin-2, tumor necrosis factor-alpha and interferon-gamma. http://purl.obolibrary.org/obo/GO_0048368 lateral mesoderm development http://purl.obolibrary.org/obo/GO_0060485 mesenchyme development The process whose specific outcome is the progression of the lateral mesoderm over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/CL_0000944 Be2 cell http://purl.obolibrary.org/obo/CL_0000968 Be cell A Be cell that facilitates development of T-helper 2 (Th2) phenotype T cells, and secretes high levels of interleukin-2, interleukin-10, interleukin-4, and interleukin-6. http://purl.obolibrary.org/obo/GO_0048468 cell development http://purl.obolibrary.org/obo/GO_0048869 cellular developmental process The cellular developmental process in which a specific cell progresses from an immature to a mature state. Cell development start once cell commitment has taken place. http://purl.obolibrary.org/obo/CL_0000945 lymphocyte of B lineage http://purl.obolibrary.org/obo/CL_0000542 lymphocyte A lymphocyte of B lineage with the commitment to express an immunoglobulin complex. http://purl.obolibrary.org/obo/GO_0048469 cell maturation http://purl.obolibrary.org/obo/GO_0071695 anatomical structure maturation The cellular developmental process, independent of morphogenetic (shape) change, that is required for a specific cell to attain its fully functional state. http://purl.obolibrary.org/obo/CL_0000946 antibody secreting cell http://purl.obolibrary.org/obo/CL_0000945 lymphocyte of B lineage A lymphocyte of B lineage that is devoted to secreting large amounts of immunoglobulin. http://purl.obolibrary.org/obo/GO_0048505 regulation of timing of cell differentiation http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation The process controlling the activation and/or rate at which relatively unspecialized cells acquire specialized features. Any process that modulates the rate, frequency or extent of the XXX at a consistent predetermined time point during its development. http://purl.obolibrary.org/obo/CL_0000947 IgE plasma cell http://purl.obolibrary.org/obo/CL_0000974 long lived plasma cell A long lived plasma cell that secretes IgE. http://purl.obolibrary.org/obo/GO_0048513 animal organ development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. http://purl.obolibrary.org/obo/CL_0000948 IgE memory B cell http://purl.obolibrary.org/obo/CL_4052108 IgD-negative class switched memory B cell A class switched memory B cell that expresses IgE on the cell surface. http://purl.obolibrary.org/obo/GO_0048514 blood vessel morphogenesis http://purl.obolibrary.org/obo/GO_0035239 tube morphogenesis The process in which the anatomical structures of blood vessels are generated and organized. The blood vessel is the vasculature carrying blood. http://purl.obolibrary.org/obo/CL_0000949 IgD plasmablast http://purl.obolibrary.org/obo/CL_0000980 plasmablast A plasmablast that secretes IgD, and which occur in a small proportion of B cells in the adult. http://purl.obolibrary.org/obo/GO_0048518 positive regulation of biological process http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. http://purl.obolibrary.org/obo/CL_0000950 IgE plasmablast http://purl.obolibrary.org/obo/CL_0000980 plasmablast A plasmablast that secretes IgE. http://purl.obolibrary.org/obo/GO_0048519 negative regulation of biological process http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process Any process that stops, prevents, or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. http://purl.obolibrary.org/obo/CL_0000951 IgE short lived plasma cell http://purl.obolibrary.org/obo/CL_0000975 short lived plasma cell A short lived plasma cell that secretes IgE. http://purl.obolibrary.org/obo/GO_0048562 embryonic organ morphogenesis http://purl.obolibrary.org/obo/GO_0048598 embryonic morphogenesis Morphogenesis, during the embryonic phase, of a tissue or tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. http://purl.obolibrary.org/obo/CL_0000952 preBCR-positive large pre-B-II cell http://purl.obolibrary.org/obo/CL_0000957 large pre-B-II cell An preBRC-positive large pre-B-II cell is a large pre-B-II cell that is pre-B cell receptor-positive, composed of surrogate light chain protein (SL), which is composed of VpreB , Lambda 5/14.1, in complex with immunoglobulin mu heavy chain (IgHmu) on the cell surface. http://purl.obolibrary.org/obo/GO_0048568 embryonic organ development http://purl.obolibrary.org/obo/GO_0048513 animal organ development Development, taking place during the embryonic phase, of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. http://purl.obolibrary.org/obo/CL_0000953 preBCR-negative large pre-B-II cell http://purl.obolibrary.org/obo/CL_0000957 large pre-B-II cell A pre-BCR-negative large pre-B-II cell is a large pre-B-II cell that is pre-B cell receptor-negative, composed of surrogate light chain protein (SL), which is composed of VpreB and Lambda 5/14.1, in complex with immunoglobulin mu heavy chain (IgHmu), on the cell surface, and lack a DNA rearrangement of immunoglobulin light chain genes. http://purl.obolibrary.org/obo/GO_0048583 regulation of response to stimulus http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process Any process that modulates the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. http://purl.obolibrary.org/obo/CL_0000954 small pre-B-II cell http://purl.obolibrary.org/obo/CL_0000955 pre-B-II cell A small pre-B-II cell is a pre-B-II cell that is Rag1-positive, Rag2-positive, pre-BCR-negative, and BCR-negative, is not proliferating, and carries a DNA rearrangement of one or more immunoglobulin light chain genes. http://purl.obolibrary.org/obo/GO_0048584 positive regulation of response to stimulus http://purl.obolibrary.org/obo/GO_0048583 regulation of response to stimulus Any process that activates, maintains or increases the rate of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. http://purl.obolibrary.org/obo/CL_0000955 pre-B-II cell http://purl.obolibrary.org/obo/CL_0000817 precursor B cell A pre-B-II cell is a precursor B cell that expresses immunoglobulin mu heavy chain (IgHmu+), and lack expression of CD34, TdT, immunoglobulin kappa light chain and immunoglobulin lambda light chain. http://purl.obolibrary.org/obo/GO_0048585 negative regulation of response to stimulus http://purl.obolibrary.org/obo/GO_0048583 regulation of response to stimulus Any process that stops, prevents, or reduces the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. http://purl.obolibrary.org/obo/CL_0000956 pre-B-I cell http://purl.obolibrary.org/obo/CL_0000817 precursor B cell A pre-B-I cell is a precursor B cell that expresses CD34 and surrogate immunoglobulin light chain (VpreB , Lambda 5 (mouse)/14.1 (human)) on the cell surface, and TdT, Rag1,and Rag2 intracellularly. Cell type carries a D-JH DNA rearrangement, and lacks expression of immunglobulin heavy chain protein. http://purl.obolibrary.org/obo/GO_0048588 developmental cell growth http://purl.obolibrary.org/obo/GO_0048589 developmental growth The growth of a cell, where growth contributes to the progression of the cell over time from one condition to another. http://purl.obolibrary.org/obo/CL_0000957 large pre-B-II cell http://purl.obolibrary.org/obo/CL_0000955 pre-B-II cell A large pre-B-II cell is a pre-B-II cell that is proliferating and is Rag1-negative and Rag2-negative. http://purl.obolibrary.org/obo/GO_0048589 developmental growth http://purl.obolibrary.org/obo/GO_0040007 growth The increase in size or mass of an entire organism, a part of an organism or a cell, where the increase in size or mass has the specific outcome of the progression of the organism over time from one condition to another. http://purl.obolibrary.org/obo/CL_0000958 T1 B cell http://purl.obolibrary.org/obo/CL_0000818 transitional stage B cell A transitional stage B cell that migrates from the bone marrow into the peripheral circulation, and finally to the spleen. This cell type has the phenotype surface IgM-positive, surface IgD-negative, CD21-negative, CD23-negative, and CD62L-negative, and CD93-positive. This cell type has also been described as IgM-high, CD19-positive, B220-positive, AA4-positive, and CD23-negative. http://purl.obolibrary.org/obo/GO_0048592 eye morphogenesis http://purl.obolibrary.org/obo/GO_0090596 sensory organ morphogenesis The process in which the anatomical structures of the eye are generated and organized. http://purl.obolibrary.org/obo/CL_0000959 T2 B cell http://purl.obolibrary.org/obo/CL_0000818 transitional stage B cell A transitional stage B cell that has the phenotype surface IgM-positive, surface IgD-postive, CD21-positive, CD23-positive, CD62L-negative, CD93-positive and is located in the splenic B follicles. This cell type has also been described as IgM-high, CD19-positive, B220-positive, AA4-positive, and CD23-positive. http://purl.obolibrary.org/obo/GO_0048593 camera-type eye morphogenesis http://purl.obolibrary.org/obo/GO_0048592 eye morphogenesis The process in which the anatomical structures of the eye are generated and organized. The camera-type eye is an organ of sight that receives light through an aperture and focuses it through a lens, projecting it on a photoreceptor field. http://purl.obolibrary.org/obo/CL_0000960 T3 B cell http://purl.obolibrary.org/obo/CL_0000818 transitional stage B cell A transitional stage B cell that expresses surface IgM and IgD, and CD62L. This cell type appears to be an anergic B cell that does not proliferate upon BCR signaling, is found in the spleen and lymph nodes, and has the phenotype surface IgM-positive, surface IgD-positive, CD21-positive, CD23-positive, CD62L-positive, and CD93-positive. This cell type has also been described as IgM-low, CD19-positive, B220-positive, AA4-positive, and CD23-positive (i.e. this cell-type is distinguished from T2 cells by surface expression of IgM). http://purl.obolibrary.org/obo/GO_0048596 embryonic camera-type eye morphogenesis http://purl.obolibrary.org/obo/GO_0048048 embryonic eye morphogenesis The process in which the anatomical structures of the eye are generated and organized during embryonic development. http://purl.obolibrary.org/obo/CL_0000961 Bm1 B cell http://purl.obolibrary.org/obo/CL_0000843 follicular B cell A follicular B cell that is IgD-positive, CD23-negative, and CD38-negative. This naive cell type is activated in the extrafollicular areas through interaction with interdigitating dendritic cells and antigen-specific CD4-positive T cells. http://purl.obolibrary.org/obo/GO_0048598 embryonic morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which anatomical structures are generated and organized during the embryonic phase. The embryonic phase begins with zygote formation. The end of the embryonic phase is organism-specific. For example, it would be at birth for mammals, larval hatching for insects and seed dormancy in plants. http://purl.obolibrary.org/obo/CL_0000962 Bm2 B cell http://purl.obolibrary.org/obo/CL_0000843 follicular B cell A follicular B cell that is IgD-positive and CD23-positive and CD38-positive. This naive cell type is activated in the extrafollicular areas via interaction with dendritic cells and antigen specific T cells. http://purl.obolibrary.org/obo/GO_0048599 oocyte development http://purl.obolibrary.org/obo/GO_0007281 germ cell development The process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell. http://purl.obolibrary.org/obo/CL_0000963 Bm3-delta B cell http://purl.obolibrary.org/obo/CL_0000844 germinal center B cell A germinal center B cell that develops from a Bm3 B cell. This cell has the phenotype IgM-negative, IgD-positive, and CD38-positive. http://purl.obolibrary.org/obo/GO_0048608 reproductive structure development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The reproductive developmental process whose specific outcome is the progression of somatic structures that will be used in the process of creating new individuals from one or more parents, from their formation to the mature structures. http://purl.obolibrary.org/obo/CL_0000964 Bm2' B cell http://purl.obolibrary.org/obo/CL_0000844 germinal center B cell A germinal center B cell that founds a germinal center, and has the phenotype IgD-positive, CD38-positive, and CD23-negative. http://purl.obolibrary.org/obo/GO_0048645 animal organ formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process pertaining to the initial formation of an animal organ from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure, such as inductive events, and ends when the structural rudiment of the organ is recognizable, such as a condensation of mesenchymal cells into the organ rudiment. Organs are a natural part or structure in an animal or a plant, capable of performing some special action (termed its function), which is essential to the life or well-being of the whole. The heart and lungs are organs of animals, and the petal and leaf are organs of plants. In animals the organs are generally made up of several tissues, one of which usually predominates, and determines the principal function of the organ. http://purl.obolibrary.org/obo/CL_0000965 Bm3 B cell http://purl.obolibrary.org/obo/CL_0000844 germinal center B cell A germinal center B cell that is rapidly dividing and has the phenotype IgD-negative, CD38-positive, and CD77-positive. Somatic hypermutation of the immunoglobulin V gene region can occur during proliferation of this cell type. http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis http://purl.obolibrary.org/obo/GO_0032502 developmental process The developmental process pertaining to the initial formation of an anatomical structure from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome. http://purl.obolibrary.org/obo/CL_0000966 Bm4 B cell http://purl.obolibrary.org/obo/CL_0000844 germinal center B cell A germinal center B cell that has the phenotype CD77-negative, IgD-negative, and CD38-positive. These cells have undergone somatic mutation of the B cell receptor. http://purl.obolibrary.org/obo/GO_0048666 neuron development http://purl.obolibrary.org/obo/GO_0048468 cell development The process whose specific outcome is the progression of a neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. http://purl.obolibrary.org/obo/CL_0000967 Bm5 B cell http://purl.obolibrary.org/obo/CL_0001053 IgD-negative memory B cell A memory B cell arising in the germinal center that is IgD-negative and has undergone somatic mutation of the variable region of the immunoglobulin heavy and light chain genes. http://purl.obolibrary.org/obo/GO_0048667 cell morphogenesis involved in neuron differentiation http://purl.obolibrary.org/obo/GO_0000902 cell morphogenesis The process in which the structures of a neuron are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a neuron. http://purl.obolibrary.org/obo/CL_0000968 Be cell http://purl.obolibrary.org/obo/CL_0000785 mature B cell A mature B cell that produces cytokines that can influence CD4 T cell differentiation. http://purl.obolibrary.org/obo/GO_0048699 generation of neurons http://purl.obolibrary.org/obo/GO_0022008 neurogenesis The process in which nerve cells are generated. This includes the production of neuroblasts and their differentiation into neurons. http://purl.obolibrary.org/obo/CL_0000969 regulatory B cell http://purl.obolibrary.org/obo/CL_0000785 mature B cell A mature B cell that has the phenotype CD1d-positive and expresses interleukin-10. This cell type has been associated with suppression of chronic inflammatory responses and T cell responses. http://purl.obolibrary.org/obo/GO_0048705 skeletal system morphogenesis http://purl.obolibrary.org/obo/GO_0009887 animal organ morphogenesis The process in which the anatomical structures of the skeleton are generated and organized. http://purl.obolibrary.org/obo/CL_0000970 unswitched memory B cell http://purl.obolibrary.org/obo/CL_0000787 memory B cell An unswitched memory B cell is a memory B cell that has the phenotype IgM-positive, IgD-positive, CD27-positive, CD138-negative, IgG-negative, IgE-negative, and IgA-negative. http://purl.obolibrary.org/obo/GO_0048729 tissue morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structures of a tissue are generated and organized. http://purl.obolibrary.org/obo/CL_0000971 IgM memory B cell http://purl.obolibrary.org/obo/CL_0001053 IgD-negative memory B cell An IgM memory B cell is an unswitched memory B cell with the phenotype IgM-positive and IgD-negative. http://purl.obolibrary.org/obo/GO_0048731 system development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process. http://purl.obolibrary.org/obo/CL_0000972 class switched memory B cell http://purl.obolibrary.org/obo/CL_0000787 memory B cell A class switched memory B cell is a memory B cell that has undergone Ig class switching and therefore is IgM-negative on the cell surface. These cells are CD27-positive and have either IgG, IgE, or IgA on the cell surface. http://purl.obolibrary.org/obo/GO_0048732 gland development http://purl.obolibrary.org/obo/GO_0048513 animal organ development The process whose specific outcome is the progression of a gland over time, from its formation to the mature structure. A gland is an organ specialised for secretion. http://purl.obolibrary.org/obo/CL_0000973 IgA memory B cell http://purl.obolibrary.org/obo/CL_4052108 IgD-negative class switched memory B cell A class switched memory B cell that expresses IgA. http://purl.obolibrary.org/obo/GO_0048733 sebaceous gland development http://purl.obolibrary.org/obo/GO_0048732 gland development The process whose specific outcome is the progression of the sebaceous gland over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/CL_0000974 long lived plasma cell http://purl.obolibrary.org/obo/CL_0000786 plasma cell A fully differentiated plasma cell that lives for years, as opposed to months, secretes immunoglobulin, and has the phenotype weakly CD19-positive, CD20-negative, CD38-negative, strongly CD138-positive, MHC Class II-negative, surface immunoglobulin-negative, IgD-negative, and strongly CXCR4-positive. The majority of these cells of this type reside in the bone marrow. http://purl.obolibrary.org/obo/GO_0048738 cardiac muscle tissue development http://purl.obolibrary.org/obo/GO_0014706 striated muscle tissue development The process whose specific outcome is the progression of cardiac muscle over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/CL_0000975 short lived plasma cell http://purl.obolibrary.org/obo/CL_0000786 plasma cell A fully differentiated plasma cell that lives for months. http://purl.obolibrary.org/obo/GO_0048749 compound eye development http://purl.obolibrary.org/obo/GO_0001654 eye development The process whose specific outcome is the progression of the compound eye over time, from its formation to the mature structure. The compound eye is an organ of sight that contains multiple repeating units, often arranged hexagonally. Each unit has its own lens and photoreceptor cell(s) and can generate either a single pixelated image or multiple images, per eye. http://purl.obolibrary.org/obo/CL_0000976 IgA short lived plasma cell http://purl.obolibrary.org/obo/CL_0000975 short lived plasma cell A short lived plasma cell that secretes IgA. These cells may be found in the bone marrow as well as in the mucosal immune system. http://purl.obolibrary.org/obo/GO_0048754 branching morphogenesis of an epithelial tube http://purl.obolibrary.org/obo/GO_0061138 morphogenesis of a branching epithelium The process in which the anatomical structures of branches in an epithelial tube are generated and organized. A tube is a long hollow cylinder. http://purl.obolibrary.org/obo/CL_0000977 IgG short lived plasma cell http://purl.obolibrary.org/obo/CL_0000975 short lived plasma cell A short lived plasma cell that secretes IgG. http://purl.obolibrary.org/obo/GO_0048762 mesenchymal cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types. http://purl.obolibrary.org/obo/CL_0000978 IgM short lived plasma cell http://purl.obolibrary.org/obo/CL_0000975 short lived plasma cell A short lived plasma cell that secretes IgM. http://purl.obolibrary.org/obo/GO_0048771 tissue remodeling http://purl.obolibrary.org/obo/GO_0032501 multicellular organismal process The reorganization or renovation of existing tissues. This process can either change the characteristics of a tissue such as in blood vessel remodeling, or result in the dynamic equilibrium of a tissue such as in bone remodeling. http://purl.obolibrary.org/obo/CL_0000979 IgG memory B cell http://purl.obolibrary.org/obo/CL_0000972 class switched memory B cell An IgG memory B cell is a class switched memory B cell that is class switched and expresses IgG on the cell surface. http://purl.obolibrary.org/obo/GO_0048845 venous blood vessel morphogenesis http://purl.obolibrary.org/obo/GO_0048514 blood vessel morphogenesis The process in which the anatomical structures of venous blood vessels are generated and organized. Veins are blood vessels that transport blood from the body and its organs to the heart. http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development http://purl.obolibrary.org/obo/GO_0032502 developmental process The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome. http://purl.obolibrary.org/obo/CL_0000980 plasmablast http://purl.obolibrary.org/obo/CL_0000946 antibody secreting cell An activated mature (naive or memory) B cell that is secreting immunoglobulin, typified by being CD27-positive, CD38-positive, CD138-negative. http://purl.obolibrary.org/obo/GO_0048858 cell projection morphogenesis http://purl.obolibrary.org/obo/GO_0030030 cell projection organization The process in which the anatomical structures of a cell projection are generated and organized. http://purl.obolibrary.org/obo/CL_0000981 double negative memory B cell http://purl.obolibrary.org/obo/CL_0001053 IgD-negative memory B cell A memory B cell with the phenotype IgD-negative and CD27-negative. http://purl.obolibrary.org/obo/GO_0048869 cellular developmental process http://purl.obolibrary.org/obo/GO_0032502 developmental process A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition. http://purl.obolibrary.org/obo/CL_0000982 IgG plasmablast http://purl.obolibrary.org/obo/CL_0000980 plasmablast A plasmablast that secretes IgG. http://purl.obolibrary.org/obo/GO_0048870 cell motility http://purl.obolibrary.org/obo/GO_0009987 cellular process Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another. http://purl.obolibrary.org/obo/CL_0000983 IgM plasmablast http://purl.obolibrary.org/obo/CL_0000980 plasmablast A plasmablast that secretes IgM. http://purl.obolibrary.org/obo/GO_0048871 multicellular organismal-level homeostasis http://purl.obolibrary.org/obo/GO_0042592 homeostatic process Any process involved in the maintenance of an internal steady state at the level of the multicellular organism. http://purl.obolibrary.org/obo/CL_0000984 IgA plasmablast http://purl.obolibrary.org/obo/CL_0000980 plasmablast A plasmablast that secretes IgA. http://purl.obolibrary.org/obo/GO_0048872 homeostasis of number of cells http://purl.obolibrary.org/obo/GO_0048871 multicellular organismal-level homeostasis Any biological process involved in the maintenance of the steady-state number of cells within a population of cells. http://purl.obolibrary.org/obo/GO_0050673 epithelial cell proliferation http://purl.obolibrary.org/obo/GO_0008283 cell population proliferation The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population. Epithelial cells make up the epithelium, the covering of internal and external surfaces of the body, including the lining of vessels and other small cavities. It consists of cells joined by small amounts of cementing substances. http://purl.obolibrary.org/obo/GO_0050678 regulation of epithelial cell proliferation http://purl.obolibrary.org/obo/GO_0042127 regulation of cell population proliferation Any process that modulates the frequency, rate or extent of epithelial cell proliferation. http://purl.obolibrary.org/obo/GO_0050679 positive regulation of epithelial cell proliferation http://purl.obolibrary.org/obo/GO_0050678 regulation of epithelial cell proliferation Any process that activates or increases the rate or extent of epithelial cell proliferation. http://purl.obolibrary.org/obo/GO_0050680 negative regulation of epithelial cell proliferation http://purl.obolibrary.org/obo/GO_0008285 negative regulation of cell population proliferation Any process that stops, prevents or reduces the rate or extent of epithelial cell proliferation. http://purl.obolibrary.org/obo/CL_0000985 IgG plasma cell http://purl.obolibrary.org/obo/CL_0000974 long lived plasma cell A fully differentiated plasma cell that secretes IgG. http://purl.obolibrary.org/obo/GO_0050727 regulation of inflammatory response http://purl.obolibrary.org/obo/GO_0031347 regulation of defense response Any process that modulates the frequency, rate or extent of the inflammatory response, the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. http://purl.obolibrary.org/obo/CL_0000986 IgM plasma cell http://purl.obolibrary.org/obo/CL_0000974 long lived plasma cell A fully differentiated plasma cell that secretes IgM. http://purl.obolibrary.org/obo/GO_0050728 negative regulation of inflammatory response http://purl.obolibrary.org/obo/GO_0032102 negative regulation of response to external stimulus Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response. http://purl.obolibrary.org/obo/CL_0000987 IgA plasma cell http://purl.obolibrary.org/obo/CL_0000974 long lived plasma cell A fully differentiated plasma cell that secretes IgA. http://purl.obolibrary.org/obo/GO_0050729 positive regulation of inflammatory response http://purl.obolibrary.org/obo/GO_0050727 regulation of inflammatory response Any process that activates or increases the frequency, rate or extent of the inflammatory response. http://purl.obolibrary.org/obo/CL_0000988 hematopoietic cell http://purl.obolibrary.org/obo/CL_0000000 cell A cell of a hematopoietic lineage. http://purl.obolibrary.org/obo/GO_0050769 positive regulation of neurogenesis http://purl.obolibrary.org/obo/GO_0050767 regulation of neurogenesis Any process that activates or increases the frequency, rate or extent of neurogenesis, the generation of cells within the nervous system. http://purl.obolibrary.org/obo/CL_0000989 CD11c-low plasmacytoid dendritic cell http://purl.obolibrary.org/obo/CL_0000784 plasmacytoid dendritic cell CD11c-low plasmacytoid dendritic cell is a leukocyte that is CD11c-low, CD45R-positive, GR1-positive and CD11b-negative. http://purl.obolibrary.org/obo/GO_0050776 regulation of immune response http://purl.obolibrary.org/obo/GO_0048583 regulation of response to stimulus Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus. http://purl.obolibrary.org/obo/CL_0000990 conventional dendritic cell http://purl.obolibrary.org/obo/CL_0000451 dendritic cell Conventional dendritic cell is a dendritic cell that is CD11c-high. http://purl.obolibrary.org/obo/GO_0050777 negative regulation of immune response http://purl.obolibrary.org/obo/GO_0050776 regulation of immune response Any process that stops, prevents, or reduces the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus. http://purl.obolibrary.org/obo/CL_0000991 CD11c-negative plasmacytoid dendritic cell http://purl.obolibrary.org/obo/CL_0000784 plasmacytoid dendritic cell CD11c-negative plasmacytoid dendritic cell is a leukocyte is CD11c-negative, CD45RA-positive, CD85g-positive(ILT7), CD123-positive, CD303-positive. http://purl.obolibrary.org/obo/GO_0050778 positive regulation of immune response http://purl.obolibrary.org/obo/GO_0050776 regulation of immune response Any process that activates or increases the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus. http://purl.obolibrary.org/obo/CL_0000992 immature CD11c-low plasmacytoid dendritic cell http://purl.obolibrary.org/obo/CL_0000989 CD11c-low plasmacytoid dendritic cell Immature CD11c-low plasmacytoid dendritic cell is a CD11c-low plasmacytoid dendritic cell that is CD80-low and CD86-low. http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process http://purl.obolibrary.org/obo/GO_0065007 biological regulation Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. http://purl.obolibrary.org/obo/CL_0000993 mature CD11c-low plasmacytoid dendritic cell http://purl.obolibrary.org/obo/CL_0000989 CD11c-low plasmacytoid dendritic cell Mature CD11c-low plasmacytoid dendritic cell is a CD11c-low plasmacytoid dendritic cell that is CD83-high and is CD80-positive, CD86-positive, and MHCII-positive. http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. http://purl.obolibrary.org/obo/CL_0000994 immature CD11c-negative plasmacytoid dendritic cell http://purl.obolibrary.org/obo/CL_0000991 CD11c-negative plasmacytoid dendritic cell Immature CD11c-negative plasmacytoid dendritic cell is a CD11c-negative plasmacytoid dendritic cell is CD80-negative, CD86-low and MHCII-low. http://purl.obolibrary.org/obo/GO_0050806 positive regulation of synaptic transmission http://purl.obolibrary.org/obo/GO_0010647 positive regulation of cell communication Any process that activates or increases the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse. http://purl.obolibrary.org/obo/CL_0000996 mature CD11c-negative plasmacytoid dendritic cell http://purl.obolibrary.org/obo/CL_0000991 CD11c-negative plasmacytoid dendritic cell Mature CD11c-negative plasmacytoid dendritic cell is a CD11c-negative plasmacytoid dendritic cell is CD80-high, CD86-high, MHCII-high and is CD83-positive. http://purl.obolibrary.org/obo/GO_0050808 synapse organization http://purl.obolibrary.org/obo/GO_0034330 cell junction organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell). http://purl.obolibrary.org/obo/CL_0000997 immature CD8-alpha-negative CD11b-positive dendritic cell http://purl.obolibrary.org/obo/CL_0000999 CD4-positive CD11b-positive dendritic cell Immature CD8-alpha-negative CD11b-positive dendritic cell is a CD8-alpha-negative CD11b-positive dendritic cell that is CD80-low, CD86-low, and MHCII-low. http://purl.obolibrary.org/obo/GO_0050865 regulation of cell activation http://purl.obolibrary.org/obo/GO_0051239 regulation of multicellular organismal process Any process that modulates the frequency, rate or extent of cell activation, the change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand. http://purl.obolibrary.org/obo/CL_0000998 CD8-alpha-negative CD11b-negative dendritic cell http://purl.obolibrary.org/obo/CL_0000990 conventional dendritic cell CD8-alpha-negative CD11b-negative dendritic cell is a conventional dendritic cell that is CD11b-negative, CD4-negative CD8-alpha-negative and is CD205-positive. This cell is able to cross- present antigen to CD8-alpha-positive T cells. http://purl.obolibrary.org/obo/GO_0050866 negative regulation of cell activation http://purl.obolibrary.org/obo/GO_0051241 negative regulation of multicellular organismal process Any process that stops, prevents, or reduces the frequency, rate or extent of cell activation. http://purl.obolibrary.org/obo/GO_0050867 positive regulation of cell activation http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the frequency, rate or extent of activation. http://purl.obolibrary.org/obo/CL_0000999 CD4-positive CD11b-positive dendritic cell http://purl.obolibrary.org/obo/CL_0002465 CD11b-positive dendritic cell CD8-alpha-negative CD11b-positive dendritic cell is a conventional dendritic cell that is CD11b-positive, CD4-positive and is CD205-negative and CD8-alpha-negative. http://purl.obolibrary.org/obo/GO_0050877 nervous system process http://purl.obolibrary.org/obo/GO_0003008 system process An organ system process carried out by any of the organs or tissues of the neurological system. http://purl.obolibrary.org/obo/CL_0001000 CD8-alpha-positive CD11b-negative dendritic cell http://purl.obolibrary.org/obo/CL_0000990 conventional dendritic cell CD8-alpha-positive CD11b-negative dendritic cell is a conventional dendritic cell that is CD11b-negative, CD4-negative and is CD205-positive and CD8-alpha-positive. http://purl.obolibrary.org/obo/GO_0050878 regulation of body fluid levels http://purl.obolibrary.org/obo/GO_0065008 regulation of biological quality Any process that modulates the levels of body fluids. http://purl.obolibrary.org/obo/CL_0001001 immature CD8-alpha-negative CD11b-negative dendritic cell http://purl.obolibrary.org/obo/CL_0000998 CD8-alpha-negative CD11b-negative dendritic cell Immature CD8-alpha-negative CD11b-negative dendritic cell is a CD8-alpha-negative CD11b-negative dendritic cell that is CD80-low, CD86-low, and MHCII-low. http://purl.obolibrary.org/obo/GO_0050881 musculoskeletal movement http://purl.obolibrary.org/obo/GO_0050879 multicellular organismal movement The movement of an organism or part of an organism using mechanoreceptors, the nervous system, striated muscle and/or the skeletal system. http://purl.obolibrary.org/obo/CL_0001002 mature CD8-alpha-negative CD11b-negative dendritic cell http://purl.obolibrary.org/obo/CL_0000998 CD8-alpha-negative CD11b-negative dendritic cell Mature CD8-alpha-negative CD11b-negative dendritic cell is a CD8-alpha-negative CD11b-negative dendritic cell that is CD80-high, CD86-high, MHCII-high and is CD83-positive. http://purl.obolibrary.org/obo/GO_0050886 endocrine process http://purl.obolibrary.org/obo/GO_0003008 system process The process that involves the secretion of or response to endocrine hormones. An endocrine hormone is a hormone released into the circulatory system. http://purl.obolibrary.org/obo/CL_0001003 mature CD8-alpha-negative CD11b-positive dendritic cell http://purl.obolibrary.org/obo/CL_0000999 CD4-positive CD11b-positive dendritic cell Mature CD8-alpha-negative CD11b-positive dendritic cell is a CD8-alpha-negative CD11b-positive dendritic cell that is CD80-high, CD86-high, MHCII-high and is CD83-positive. http://purl.obolibrary.org/obo/GO_0050891 multicellular organismal-level water homeostasis http://purl.obolibrary.org/obo/GO_0140962 multicellular organismal-level chemical homeostasis A chemical homeostatic process involved in the maintenance of a steady state level of water within extracellular body fluids, such as blood, xylem or phloem, of a multicellular organism. This is distinct from maintenance of cellular homeostasis, which occurs within a cell. http://purl.obolibrary.org/obo/CL_0001004 immature CD8-alpha-positive CD11b-negative dendritic cell http://purl.obolibrary.org/obo/CL_0001000 CD8-alpha-positive CD11b-negative dendritic cell Immature CD8-alpha-positive CD11b-negative dendritic cell is a CD8-alpha-positive CD11b-negative dendritic cell that is CD80-low, CD86-low, and MHCII-low. http://purl.obolibrary.org/obo/GO_0050900 leukocyte migration http://purl.obolibrary.org/obo/GO_0016477 cell migration The movement of a leukocyte within or between different tissues and organs of the body. http://purl.obolibrary.org/obo/CL_0001005 mature CD8-alpha-positive CD11b-negative dendritic cell http://purl.obolibrary.org/obo/CL_0001000 CD8-alpha-positive CD11b-negative dendritic cell Mature CD8-alpha-positive CD11b-negative dendritic cell is a CD8-alpha-positive CD11b-negative dendritic cell that is CD80-high, CD86-high, MHCII-high and is CD83-positive. http://purl.obolibrary.org/obo/GO_0050905 neuromuscular process http://purl.obolibrary.org/obo/GO_0050877 nervous system process Any process pertaining to the functions of the nervous and muscular systems of an organism. http://purl.obolibrary.org/obo/CL_0001006 dermal dendritic cell http://purl.obolibrary.org/obo/CL_0002465 CD11b-positive dendritic cell Dermal dendritic cell is a conventional dendritic cell that is CD11b-positive, CD205-positive and CD8 alpha-negative. http://purl.obolibrary.org/obo/GO_0050912 detection of chemical stimulus involved in sensory perception of taste http://purl.obolibrary.org/obo/GO_0050907 detection of chemical stimulus involved in sensory perception The series of events involved in the perception of taste in which a gustatory chemical stimulus is received and converted into a molecular signal. http://purl.obolibrary.org/obo/CL_0001007 interstitial dendritic cell http://purl.obolibrary.org/obo/CL_0002465 CD11b-positive dendritic cell Interstitial dendritic cell is a conventional dendritic cell that is CD11b-positive, CD1a-positive, CD206-positive, CD209-positive, and CD36-positive. http://purl.obolibrary.org/obo/GO_0050920 regulation of chemotaxis http://purl.obolibrary.org/obo/GO_0040012 regulation of locomotion Any process that modulates the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient. http://purl.obolibrary.org/obo/CL_0001008 Kit and Sca1-positive hematopoietic stem cell http://purl.obolibrary.org/obo/CL_0000037 hematopoietic stem cell A hematopoietic stem cell that has plasma membrane part Kit-positive, SCA-1-positive, CD150-positive and CD34-negative. http://purl.obolibrary.org/obo/GO_0050921 positive regulation of chemotaxis http://purl.obolibrary.org/obo/GO_0040017 positive regulation of locomotion Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient. http://purl.obolibrary.org/obo/CL_0001009 immature dermal dendritic cell http://purl.obolibrary.org/obo/CL_0001006 dermal dendritic cell Immature dermal dendritic cell is a dermal dendritic cell that is CD80-low, CD86-low, and MHCII-low. http://purl.obolibrary.org/obo/GO_0050922 negative regulation of chemotaxis http://purl.obolibrary.org/obo/GO_0032102 negative regulation of response to external stimulus Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient. http://purl.obolibrary.org/obo/CL_0001010 mature dermal dendritic cell http://purl.obolibrary.org/obo/CL_0001006 dermal dendritic cell Mature dermal dendritic cell is a dermal dendritic cell that is CD80-high, CD86-high, MHCII-high and is CD83-positive. http://purl.obolibrary.org/obo/GO_0050982 detection of mechanical stimulus http://purl.obolibrary.org/obo/GO_0009582 detection of abiotic stimulus The series of events by which a mechanical stimulus is received and converted into a molecular signal. http://purl.obolibrary.org/obo/CL_0001011 immature interstitial dendritic cell http://purl.obolibrary.org/obo/CL_0001007 interstitial dendritic cell Immature interstitial dendritic cell is a interstitial dendritic cell that is CD80-low, CD86-low, and MHCII-low. http://purl.obolibrary.org/obo/GO_0051046 regulation of secretion http://purl.obolibrary.org/obo/GO_0051049 regulation of transport Any process that modulates the frequency, rate or extent of the controlled release of a substance from a cell or a tissue. http://purl.obolibrary.org/obo/CL_0001013 mature interstitial dendritic cell http://purl.obolibrary.org/obo/CL_0001007 interstitial dendritic cell Mature interstitial dendritic cell is a interstitial dendritic cell that is CD80-high, CD86-high, MHCII-high and is CD83-positive. http://purl.obolibrary.org/obo/GO_0051047 positive regulation of secretion http://purl.obolibrary.org/obo/GO_0051050 positive regulation of transport Any process that activates or increases the frequency, rate or extent of the controlled release of a substance from a cell or a tissue. http://purl.obolibrary.org/obo/CL_0001014 CD1a-positive Langerhans cell http://purl.obolibrary.org/obo/CL_0000453 Langerhans cell CD1a-positive Langerhans cell is a Langerhans_cell that is CD1a-positive and CD324-positive. http://purl.obolibrary.org/obo/GO_0051048 negative regulation of secretion http://purl.obolibrary.org/obo/GO_0051051 negative regulation of transport Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a substance from a cell or a tissue. http://purl.obolibrary.org/obo/CL_0001015 CD8-alpha-low Langerhans cell http://purl.obolibrary.org/obo/CL_0000453 Langerhans cell CD8-alpha-low Langerhans cell is a Langerhans cell that is CD205-high and is CD8-alpha-low. http://purl.obolibrary.org/obo/GO_0051052 regulation of DNA metabolic process http://purl.obolibrary.org/obo/GO_0060255 regulation of macromolecule metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving DNA. http://purl.obolibrary.org/obo/CL_0001016 immature CD1a-positive Langerhans cell http://purl.obolibrary.org/obo/CL_0001014 CD1a-positive Langerhans cell Immature CD1a-positive Langerhans cell is a CD1a-positive Langerhans cell that is CD80-low, CD86-low, and MHCII-low. http://purl.obolibrary.org/obo/GO_0051093 negative regulation of developmental process http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that stops, prevents or reduces the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). http://purl.obolibrary.org/obo/CL_0001017 mature CD1a-positive Langerhans cell http://purl.obolibrary.org/obo/CL_0001014 CD1a-positive Langerhans cell Mature CD1a-positive Langerhans cell is a CD1a-positive Langerhans cell that is CD80-high, CD86-high, MHCII-high and is CD83-positive. http://purl.obolibrary.org/obo/GO_0051094 positive regulation of developmental process http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that activates or increases the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). http://purl.obolibrary.org/obo/CL_0001018 immature CD8-alpha-low Langerhans cell http://purl.obolibrary.org/obo/CL_0001015 CD8-alpha-low Langerhans cell Immature CD8-alpha-low Langerhans cell is a CD8-alpha-low Langerhans cell that is CD80-low, CD86-low, and MHCII-low. http://purl.obolibrary.org/obo/GO_0051128 regulation of cellular component organization http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope. http://purl.obolibrary.org/obo/CL_0001020 mature CD8-alpha-low Langerhans cell http://purl.obolibrary.org/obo/CL_0001015 CD8-alpha-low Langerhans cell Mature CD8-alpha-low Langerhans cell is a CD8-alpha-low Langerhans cell that that is CD80-high, CD86-high, MHCII-high and is CD83-positive. http://purl.obolibrary.org/obo/GO_0051132 NK T cell activation http://purl.obolibrary.org/obo/GO_0046631 alpha-beta T cell activation The change in morphology and behavior of a mature or immature natural killer T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. http://purl.obolibrary.org/obo/CL_0001021 CD34-positive, CD38-positive common lymphoid progenitor http://purl.obolibrary.org/obo/CL_0000995 CD34-positive, CD38-positive common myeloid progenitor OR CD34-positive, CD38-positive common lymphoid progenitor A common lymphoid progenitor that is CD10-positive, CD45RA-positive, CD34-positive and CD38-positive. http://purl.obolibrary.org/obo/CL_0001022 CD115-positive monocyte http://purl.obolibrary.org/obo/CL_0001019 CD115-positive monocyte OR common dendritic progenitor CD115-positive monocyte is a monocyte that is CD115-positive and CD11b-positive. http://purl.obolibrary.org/obo/GO_0051216 cartilage development http://purl.obolibrary.org/obo/GO_0048513 animal organ development The process whose specific outcome is the progression of a cartilage element over time, from its formation to the mature structure. Cartilage elements are skeletal elements that consist of connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate. http://purl.obolibrary.org/obo/CL_0001023 Kit-positive, CD34-positive common myeloid progenitor http://purl.obolibrary.org/obo/CL_0001059 common myeloid progenitor, CD34-positive A common myeloid progenitor that is Kit-positive and CD34-positive, Il7ra-negative, and is SCA1-low and Fcgr2-low and Fcgr3-low. http://purl.obolibrary.org/obo/GO_0051239 regulation of multicellular organismal process http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs. http://purl.obolibrary.org/obo/CL_0001024 CD34-positive, CD38-negative hematopoietic stem cell http://purl.obolibrary.org/obo/CL_0000037 hematopoietic stem cell CD133-positive hematopoietic stem cell is a hematopoietic stem cell that is CD34-positive, CD90-positive, and CD133-positive. http://purl.obolibrary.org/obo/GO_0051240 positive regulation of multicellular organismal process http://purl.obolibrary.org/obo/GO_0051239 regulation of multicellular organismal process Any process that activates or increases the frequency, rate or extent of an organismal process, any of the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs. http://purl.obolibrary.org/obo/CL_0001025 Kit-positive, Sca1-positive common lymphoid progenitor http://purl.obolibrary.org/obo/CL_0001030 CD117-positive common myeloid progenitor OR CD217-positive common lymphoid progenitor A common lymphoid progenitor that is Kit-low, FLT3-positive, IL7ralpha-positive, and SCA1-low. http://purl.obolibrary.org/obo/GO_0051241 negative regulation of multicellular organismal process http://purl.obolibrary.org/obo/GO_0051239 regulation of multicellular organismal process Any process that stops, prevents, or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs. http://purl.obolibrary.org/obo/CL_0001026 CD34-positive, CD38-positive common myeloid progenitor http://purl.obolibrary.org/obo/CL_0001059 common myeloid progenitor, CD34-positive A common myeloid progenitor that is CD34-positive, CD38-positive, IL3ra-low, CD10-negative, CD7-negative, CD45RA-negative, and IL-5Ralpha-negative. http://purl.obolibrary.org/obo/GO_0051252 regulation of RNA metabolic process http://purl.obolibrary.org/obo/GO_0060255 regulation of macromolecule metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving RNA. http://purl.obolibrary.org/obo/CL_0001027 CD7-negative lymphoid progenitor cell http://purl.obolibrary.org/obo/CL_0001012 CD7-negative lymphoid progenitor OR granulocyte monocyte progenitor CD7-negative lymphoid progenitor cell is a lymphoid progenitor cell that is CD34-positive, CD7-negative and CD45RA-negative. http://purl.obolibrary.org/obo/GO_0051254 positive regulation of RNA metabolic process http://purl.obolibrary.org/obo/GO_0051252 regulation of RNA metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving RNA. http://purl.obolibrary.org/obo/CL_0001028 CD7-positive lymphoid progenitor cell http://purl.obolibrary.org/obo/CL_0000051 common lymphoid progenitor CD7-positive lymphoid progenitor cell is a lymphoid progenitor cell that is CD34-positive, CD7-positive and is CD45RA-negative. http://purl.obolibrary.org/obo/GO_0051258 protein polymerization http://purl.obolibrary.org/obo/GO_0065003 protein-containing complex assembly The process of creating protein polymers, compounds composed of a large number of component monomers; polymeric proteins may be made up of different or identical monomers. Polymerization occurs by the addition of extra monomers to an existing poly- or oligomeric protein. http://purl.obolibrary.org/obo/CL_0001029 common dendritic progenitor http://purl.obolibrary.org/obo/CL_0001019 CD115-positive monocyte OR common dendritic progenitor Common dendritic precursor is a hematopoietic progenitor cell that is CD117-low, CD135-positive, CD115-positive and lacks plasma membrane parts for hematopoietic lineage markers. http://purl.obolibrary.org/obo/GO_0051276 chromosome organization http://purl.obolibrary.org/obo/GO_0006996 organelle organization A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of chromosomes, structures composed of a very long molecule of DNA and associated proteins that carries hereditary information. This term covers covalent modifications at the molecular level as well as spatial relationships among the major components of a chromosome. http://purl.obolibrary.org/obo/GO_0051301 cell division http://purl.obolibrary.org/obo/GO_0009987 cellular process The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells. http://purl.obolibrary.org/obo/CL_0001031 cerebellar granule cell http://purl.obolibrary.org/obo/CL_2000028 cerebellum glutamatergic neuron An excitatory granule cell with a soma located in the granular layer of cerebellar cortex. A mature cerebellar granule cell has short dendrites with a characteristic claw-like appearance and a long axon that ascends to the molecular layer where it bifurcates (except in non-teleost fish, where it does not bifurcate) and extends mediolaterally to form parallel fibers. http://purl.obolibrary.org/obo/GO_0051302 regulation of cell division http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of the physical partitioning and separation of a cell into daughter cells. http://purl.obolibrary.org/obo/CL_0001032 cortical granule cell http://purl.obolibrary.org/obo/CL_0010012 cerebral cortex neuron Granule cell that is part of the cerebral cortex. http://purl.obolibrary.org/obo/GO_0051321 meiotic cell cycle http://purl.obolibrary.org/obo/GO_0022414 reproductive process Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell via two nuclear divisions. http://purl.obolibrary.org/obo/CL_0001033 hippocampal granule cell http://purl.obolibrary.org/obo/CL_0002608 hippocampal neuron Granule cell with a soma found in the hippocampus. http://purl.obolibrary.org/obo/GO_0051493 regulation of cytoskeleton organization http://purl.obolibrary.org/obo/GO_0033043 regulation of organelle organization Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures. http://purl.obolibrary.org/obo/CL_0001034 cell in vitro http://purl.obolibrary.org/obo/CL_0000000 cell A cell that is maintained or propagated in a controlled artificial environment for use in an investigation. http://purl.obolibrary.org/obo/GO_0051503 adenine nucleotide transport http://purl.obolibrary.org/obo/GO_0015865 purine nucleotide transport The directed movement of adenine nucleotides, ATP, ADP, and/or AMP, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/CL_0001035 bone cell http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell A connective tissue cell found in bone. http://purl.obolibrary.org/obo/GO_0051590 positive regulation of neurotransmitter transport http://purl.obolibrary.org/obo/GO_0051050 positive regulation of transport Any process that activates or increases the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/CL_0001039 terminally differentiated osteoblast http://purl.obolibrary.org/obo/CL_0000062 osteoblast Osteoblast that is terminally differentiated, located adjacent to acellular or cellular bone tissue within periosteum, and is capable of mineralizing the matrix. http://purl.obolibrary.org/obo/GO_0051608 histamine transport http://purl.obolibrary.org/obo/GO_0071705 nitrogen compound transport The directed movement of histamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Histamine is a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans. http://purl.obolibrary.org/obo/CL_0001040 non-terminally differentiated osteoblast http://purl.obolibrary.org/obo/CL_0011026 progenitor cell Osteoblast that is non-terminally differentiated and located in cellular bone tissue or under the periosteum in acellular bone. http://purl.obolibrary.org/obo/GO_0051707 response to other organism http://purl.obolibrary.org/obo/GO_0044419 biological process involved in interspecies interaction between organisms Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from another living organism. http://purl.obolibrary.org/obo/CL_0001041 CD8-positive, CXCR3-positive, alpha-beta regulatory T cell http://purl.obolibrary.org/obo/CL_0000795 CD8-positive, alpha-beta regulatory T cell A CD8-positive alpha-beta-positive T cell with the phenotype CXCR3-positive and having suppressor function. They are capable of producing IL-10, suppressing proliferation, and suppressing IFN-gamma production. http://purl.obolibrary.org/obo/GO_0051726 regulation of cell cycle http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that modulates the rate or extent of progression through the cell cycle. http://purl.obolibrary.org/obo/CL_0001042 T-helper 22 cell http://purl.obolibrary.org/obo/CL_0000492 CD4-positive helper T cell CD4-positive, alpha-beta T cell that produces IL-22. http://purl.obolibrary.org/obo/GO_0051899 membrane depolarization http://purl.obolibrary.org/obo/GO_0042391 regulation of membrane potential The process in which membrane potential decreases with respect to its steady-state potential, usually from negative potential to a more positive potential. For example, the initial depolarization during the rising phase of an action potential is in the direction from the negative steady-state resting potential towards the positive membrane potential that will be the peak of the action potential. http://purl.obolibrary.org/obo/CL_0001043 activated CD4-positive, alpha-beta T cell, human http://purl.obolibrary.org/obo/CL_0000896 activated CD4-positive, alpha-beta T cell A recently activated CD4-positive, alpha-beta T cell with the phenotype HLA-DRA-positive, CD38-positive, CD69-positive, CD62L-negative, CD127-negative, and CD25-positive. http://purl.obolibrary.org/obo/GO_0051955 regulation of amino acid transport http://purl.obolibrary.org/obo/GO_0051952 regulation of amine transport Any process that modulates the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/CL_0001044 effector CD4-positive, alpha-beta T cell http://purl.obolibrary.org/obo/CL_0000911 effector T cell A CD4-positive, alpha-beta T cell with the phenotype CCR7-negative, CD45RA-positive. http://purl.obolibrary.org/obo/GO_0051956 negative regulation of amino acid transport http://purl.obolibrary.org/obo/GO_0051953 negative regulation of amine transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/CL_0001045 naive CCR4-positive regulatory T cell http://purl.obolibrary.org/obo/CL_0002677 naive regulatory T cell A naive regulatory T cell with the phenotype CD4-positive, CD25-positive, CD127lo, CCR4-positive, and CD45RO-negative. http://purl.obolibrary.org/obo/GO_0051957 positive regulation of amino acid transport http://purl.obolibrary.org/obo/GO_0051954 positive regulation of amine transport Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/CL_0001046 memory CCR4-positive regulatory T cell http://purl.obolibrary.org/obo/CL_0002678 memory regulatory T cell A memory regulatory T cell with phenotype CD4-positive, CD25-positive, CD127lo, CCR4-positive, and CD45RO-positive. http://purl.obolibrary.org/obo/GO_0052803 imidazole-containing compound metabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process The chemical reactions and pathways involving imidazoles, five-membered organic heterocycle containing two nitrogen atoms at positions 1 and 3, or any of its derivatives; compounds containing an imidazole skeleton. http://purl.obolibrary.org/obo/CL_0001047 CD4-positive, CD25-positive, CCR4-positive, alpha-beta regulatory T cell http://purl.obolibrary.org/obo/CL_0000792 CD4-positive, CD25-positive, alpha-beta regulatory T cell A CD4-positive, CD25-positive, alpha-beta regulatory T cell with the additional phenotype CCR4-positive. http://purl.obolibrary.org/obo/CL_0001048 activated CD4-positive, CD25-positive, CCR4-positive, alpha-beta regulatory T cell, human http://purl.obolibrary.org/obo/CL_0001047 CD4-positive, CD25-positive, CCR4-positive, alpha-beta regulatory T cell A CD4-positive, CD25-positive, CCR4-positive, alpha-beta T regulatory cell with the phenotype HLA-DRA-positive, indicating recent activation. http://purl.obolibrary.org/obo/GO_0052805 imidazole-containing compound catabolic process http://purl.obolibrary.org/obo/GO_0009056 catabolic process The chemical reactions and pathways resulting in the breakdown of imidazoles, five-membered organic heterocycle containing two nitrogen atoms at positions 1 and 3, or any of its derivatives; compounds containing an imidazole skeleton. http://purl.obolibrary.org/obo/CL_0001049 activated CD8-positive, alpha-beta T cell, human http://purl.obolibrary.org/obo/CL_0000906 activated CD8-positive, alpha-beta T cell A recently activated CD8-positive, alpha-beta T cell with the phenotype HLA-DRA-positive, CD38-positive, CD69-positive, CD62L-negative, CD127-negative, CCR7-negative, and CD25-positive. http://purl.obolibrary.org/obo/GO_0055008 cardiac muscle tissue morphogenesis http://purl.obolibrary.org/obo/GO_0060415 muscle tissue morphogenesis The process in which the anatomical structures of cardiac muscle tissue are generated and organized. http://purl.obolibrary.org/obo/CL_0001050 effector CD8-positive, alpha-beta T cell http://purl.obolibrary.org/obo/CL_0000911 effector T cell A CD8-positive, alpha-beta T cell with the phenotype CCR7-negative, CD45RA-positive. http://purl.obolibrary.org/obo/GO_0055010 ventricular cardiac muscle tissue morphogenesis http://purl.obolibrary.org/obo/GO_0055008 cardiac muscle tissue morphogenesis The process in which the anatomical structures of cardiac ventricle muscle is generated and organized. http://purl.obolibrary.org/obo/CL_0001051 CD4-positive, CXCR3-negative, CCR6-negative, alpha-beta T cell http://purl.obolibrary.org/obo/CL_0000624 CD4-positive, alpha-beta T cell A CD4-positive, alpha-beta T cell that has the phenotype CXCR3-negative, CCR6-negative. http://purl.obolibrary.org/obo/GO_0055017 cardiac muscle tissue growth http://purl.obolibrary.org/obo/GO_0048589 developmental growth The increase in size or mass of a cardiac muscle, where the increase in size or mass has the specific outcome of the progression of the organism over time from one condition to another. http://purl.obolibrary.org/obo/CL_0001052 CD8-positive, CXCR3-negative, CCR6-negative, alpha-beta T cell http://purl.obolibrary.org/obo/CL_0000625 CD8-positive, alpha-beta T cell A CD8-positive, alpha-beta T cell that has the phenotype CXCR3-negative, CCR6-negative. http://purl.obolibrary.org/obo/GO_0055082 intracellular chemical homeostasis http://purl.obolibrary.org/obo/GO_0048878 chemical homeostasis A homeostatic process involved in the maintenance of a steady state level of a chemical within a cell. http://purl.obolibrary.org/obo/GO_0060039 pericardium development http://purl.obolibrary.org/obo/GO_0060429 epithelium development The process whose specific outcome is the progression of the pericardium over time, from its formation to the mature structure. The pericardium is a double-walled sac that contains the heart and the roots of the aorta, vena cava and the pulmonary artery. http://purl.obolibrary.org/obo/GO_0060041 retina development in camera-type eye http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the retina over time, from its formation to the mature structure. The retina is the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates. http://purl.obolibrary.org/obo/GO_0060117 auditory receptor cell development http://purl.obolibrary.org/obo/GO_0060119 inner ear receptor cell development The process whose specific outcome is the progression of an auditory receptor cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. http://purl.obolibrary.org/obo/GO_0060135 maternal process involved in female pregnancy http://purl.obolibrary.org/obo/GO_0048609 multicellular organismal reproductive process A reproductive process occurring in the mother that allows an embryo or fetus to develop within it. http://purl.obolibrary.org/obo/GO_0060231 mesenchymal to epithelial transition http://purl.obolibrary.org/obo/GO_0030855 epithelial cell differentiation A transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell. http://purl.obolibrary.org/obo/GO_0060249 anatomical structure homeostasis http://purl.obolibrary.org/obo/GO_0048871 multicellular organismal-level homeostasis A homeostatic process involved in the maintenance of an internal steady state within a defined anatomical structure of an organism, including control of cellular proliferation and death and control of metabolic function. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome. http://purl.obolibrary.org/obo/CL_0001053 IgD-negative memory B cell http://purl.obolibrary.org/obo/CL_0000787 memory B cell A memory B cell that lacks expression of surface IgD. http://purl.obolibrary.org/obo/GO_0060255 regulation of macromolecule metabolic process http://purl.obolibrary.org/obo/GO_0019222 regulation of metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. http://purl.obolibrary.org/obo/GO_0060350 endochondral bone morphogenesis http://purl.obolibrary.org/obo/GO_0060349 bone morphogenesis The process in which bones are generated and organized as a result of the conversion of initial cartilaginous anlage into bone. http://purl.obolibrary.org/obo/GO_0060351 cartilage development involved in endochondral bone morphogenesis http://purl.obolibrary.org/obo/GO_0051216 cartilage development The process whose specific outcome is the progression of the cartilage that will provide a scaffold for mineralization of endochondral bones. http://purl.obolibrary.org/obo/GO_0060379 cardiac muscle cell myoblast differentiation http://purl.obolibrary.org/obo/GO_0045445 myoblast differentiation The process in which a relatively unspecialized cell acquires specialized features of a cardiac myoblast. A cardiac myoblast is a precursor cell that has been committed to a cardiac muscle cell fate but retains the ability to divide and proliferate throughout life. http://purl.obolibrary.org/obo/CL_0001054 CD14-positive monocyte http://purl.obolibrary.org/obo/CL_0000576 monocyte A monocyte that expresses CD14 and is negative for the lineage markers CD3, CD19, and CD20. http://purl.obolibrary.org/obo/CL_0001055 CD14-positive, CD16-low monocyte http://purl.obolibrary.org/obo/CL_0002397 CD14-positive, CD16-positive monocyte An intermediate monocyte that is CD14-positive and with low amounts of CD16. http://purl.obolibrary.org/obo/GO_0060411 cardiac septum morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structure of a cardiac septum is generated and organized. A cardiac septum is a partition that separates parts of the heart. http://purl.obolibrary.org/obo/CL_0001056 dendritic cell, human http://purl.obolibrary.org/obo/CL_0000451 dendritic cell A dendritic cell with the phenotype HLA-DRA-positive. http://purl.obolibrary.org/obo/GO_0060412 ventricular septum morphogenesis http://purl.obolibrary.org/obo/GO_0060411 cardiac septum morphogenesis The developmental process in which a ventricular septum is generated and organized. A ventricular septum is an anatomical structure that separates the lower chambers (ventricles) of the heart from one another. http://purl.obolibrary.org/obo/CL_0001057 myeloid dendritic cell, human http://purl.obolibrary.org/obo/CL_0001056 dendritic cell, human A myeloid dendritic cell with the phenotype HLA-DRA-positive and CD14-negative. http://purl.obolibrary.org/obo/CL_0001058 plasmacytoid dendritic cell, human http://purl.obolibrary.org/obo/CL_0001056 dendritic cell, human A plasmacytoid dendritic cell with the phenotype HLA-DRA-positive, CD123-positive, CD11c-negative, and CD14-negative. http://purl.obolibrary.org/obo/GO_0060413 atrial septum morphogenesis http://purl.obolibrary.org/obo/GO_0060411 cardiac septum morphogenesis The developmental process in which atrial septum is generated and organized. The atrial septum separates the upper chambers (the atria) of the heart from one another. http://purl.obolibrary.org/obo/CL_0001059 common myeloid progenitor, CD34-positive http://purl.obolibrary.org/obo/CL_0011026 progenitor cell A progenitor cell committed to myeloid lineage, including the megakaryocyte and erythroid lineages. These cells are CD34-positive, and express Gata1, Gata2, C/EBPa, and Pu.1. http://purl.obolibrary.org/obo/CL_0001060 hematopoietic oligopotent progenitor cell, lineage-negative http://purl.obolibrary.org/obo/CL_0002032 hematopoietic oligopotent progenitor cell A hematopoietic oligopotent progenitor cell that has the ability to differentiate into limited cell types but lacks lineage cell markers and self renewal capabilities. Cell lacks hematopoeitic lineage markers. http://purl.obolibrary.org/obo/GO_0060415 muscle tissue morphogenesis http://purl.obolibrary.org/obo/GO_0048729 tissue morphogenesis The process in which the anatomical structures of muscle tissue are generated and organized. Muscle tissue consists of a set of cells that are part of an organ and carry out a contractive function. http://purl.obolibrary.org/obo/CL_0001062 effector memory CD8-positive, alpha-beta T cell, terminally differentiated http://purl.obolibrary.org/obo/CL_4030002 effector memory CD45RA-positive, alpha-beta T cell, terminally differentiated A CD8-positive, alpha beta memory T cell with the phenotype CD45RA-positive, CD45RO-negative, and CCR7-negative. http://purl.obolibrary.org/obo/CL_0002000 Kit-positive erythroid progenitor cell http://purl.obolibrary.org/obo/CL_0001066 erythroid progenitor cell, mammalian An erythroid progenitor cell is Kit-positive, Ly6A-negative, CD41-negative, CD127-negative, and CD123-negative. This cell type is also described as being lin-negative, Kit-positive, CD150-negative, CD41-negative, CD105-positive, and FcgR-negative. http://purl.obolibrary.org/obo/GO_0060419 heart growth http://purl.obolibrary.org/obo/GO_0035265 organ growth The increase in size or mass of the heart. http://purl.obolibrary.org/obo/CL_0002001 CD34-positive, CD38-positive granulocyte monocyte progenitor http://purl.obolibrary.org/obo/CL_0000557 granulocyte monocyte progenitor cell A granulocyte monocyte progenitor is CD34-positive, CD38-positive, IL-3receptor-alpha-positive and is CD45RA-negative. http://purl.obolibrary.org/obo/CL_0002002 Kit-positive granulocyte monocyte progenitor http://purl.obolibrary.org/obo/CL_0000557 granulocyte monocyte progenitor cell A granulocyte monocyte progenitor that is Kit-positive, CD34-positive, Fc-gamma receptor II/II-positive, and is Sca-1-negative, Il7ra-negative, Cxc3r1-negative, and CD90-negative. http://purl.obolibrary.org/obo/GO_0060429 epithelium development http://purl.obolibrary.org/obo/GO_0009888 tissue development The process whose specific outcome is the progression of an epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. http://purl.obolibrary.org/obo/CL_0002003 CD34-positive, GlyA-negative erythroid progenitor cell http://purl.obolibrary.org/obo/CL_0001066 erythroid progenitor cell, mammalian An erythroid progenitor cell that is CD34-positive and is GlyA-negative. http://purl.obolibrary.org/obo/GO_0060485 mesenchyme development http://purl.obolibrary.org/obo/GO_0009888 tissue development The process whose specific outcome is the progression of a mesenchymal tissue over time, from its formation to the mature structure. A mesenchymal tissue is made up of loosely packed stellate cells. http://purl.obolibrary.org/obo/CL_0002004 CD34-negative, GlyA-negative proerythroblast http://purl.obolibrary.org/obo/CL_0000547 proerythroblast A proerythoblast that is CD34-negative and GlyA-negative. http://purl.obolibrary.org/obo/CL_0002005 CD34-positive, CD38-positive megakaryocyte erythroid progenitor cell http://purl.obolibrary.org/obo/CL_0000050 megakaryocyte-erythroid progenitor cell A megakaryocyte erythroid progenitor cell is CD34-positive, CD38-positive and is IL3-receptor alpha-negative and CD45RA-negative. http://purl.obolibrary.org/obo/GO_0060536 cartilage morphogenesis http://purl.obolibrary.org/obo/GO_0048729 tissue morphogenesis The process in which the anatomical structures of cartilage are generated and organized. http://purl.obolibrary.org/obo/CL_0002006 Kit-positive, CD34-negative megakaryocyte erythroid progenitor cell http://purl.obolibrary.org/obo/CL_0000050 megakaryocyte-erythroid progenitor cell A megakaryocyte erythroid progenitor cell that is Kit-positive and is Sca1-negative, CD34-negative, CD90-negative, IL7r-alpha-negative and Fcgr II/III-low. http://purl.obolibrary.org/obo/CL_0002007 Kit-low, CD34-positive eosinophil progenitor cell http://purl.obolibrary.org/obo/CL_0000611 eosinophil progenitor cell A lineage marker-negative, CD34-positive, IL5r-alpha-positive, and Sca1-negative eosinophil progenitor cell. http://purl.obolibrary.org/obo/GO_0060538 skeletal muscle organ development http://purl.obolibrary.org/obo/GO_0007517 muscle organ development The progression of a skeletal muscle organ over time from its initial formation to its mature state. A skeletal muscle organ includes the skeletal muscle tissue and its associated connective tissue. http://purl.obolibrary.org/obo/CL_0002008 CD34-positive, CD38-positive eosinophil progenitor cell http://purl.obolibrary.org/obo/CL_0000611 eosinophil progenitor cell A lineage marker-negative, CD34-positive, CD38-positive, IL3r-alpha-positive, IL5r-alpha-positive, and CD45RA-negative eosinophil progenitor cell. http://purl.obolibrary.org/obo/CL_0002009 macrophage dendritic cell progenitor http://purl.obolibrary.org/obo/CL_0011026 progenitor cell A progenitor cell that can give rise to plasmacytoid and myeloid dendritic cells, and to monocytes and macrophages. http://purl.obolibrary.org/obo/GO_0060560 developmental growth involved in morphogenesis http://purl.obolibrary.org/obo/GO_0048589 developmental growth The increase in size or mass of an anatomical structure that contributes to the structure attaining its shape. http://purl.obolibrary.org/obo/CL_0002010 pre-conventional dendritic cell http://purl.obolibrary.org/obo/CL_0002031 hematopoietic lineage restricted progenitor cell A lin-negative, MHC-II-negative, CD11c-positive, FLT3-positive cell with intermediate expression of SIRP-alpha. http://purl.obolibrary.org/obo/CL_0002011 Kit-positive macrophage dendritic cell progenitor http://purl.obolibrary.org/obo/CL_0002009 macrophage dendritic cell progenitor A progenitor cell that can give rise to plasmacytoid and myeloid dendritic cells, and to monocytes and macrophages. Marker for this cell is Kit-high, CD115-positive, CD135-positive, Cx3cr1-positive, and is Il7ra-negative. http://purl.obolibrary.org/obo/GO_0060561 apoptotic process involved in morphogenesis http://purl.obolibrary.org/obo/GO_1902742 apoptotic process involved in development Any apoptotic process that contributes to the shaping of an anatomical structure. http://purl.obolibrary.org/obo/CL_0002012 Kit-low proerythroblast http://purl.obolibrary.org/obo/CL_0000547 proerythroblast A proerythoblast that is Kit-low, Lyg76-positive, and CD71-positive. http://purl.obolibrary.org/obo/GO_0060562 epithelial tube morphogenesis http://purl.obolibrary.org/obo/GO_0002009 morphogenesis of an epithelium The process in which the anatomical structures of a tube are generated and organized from an epithelium. Epithelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system. http://purl.obolibrary.org/obo/CL_0002013 GlyA-positive basophilic erythroblast http://purl.obolibrary.org/obo/CL_0000549 basophilic erythroblast A basophilic erythroblast that is GlyA-positive. http://purl.obolibrary.org/obo/CL_0002014 Kit-negative, Ly-76 high basophilic erythroblast http://purl.obolibrary.org/obo/CL_0000549 basophilic erythroblast A basophilic erythroblast that is Lyg 76-high and is Kit-negative. http://purl.obolibrary.org/obo/GO_0060563 neuroepithelial cell differentiation http://purl.obolibrary.org/obo/GO_0002065 columnar/cuboidal epithelial cell differentiation The process in which epiblast cells acquire specialized features of neuroepithelial cells. http://purl.obolibrary.org/obo/CL_0002015 Kit-negative, Ly-76 high polychromatophilic erythroblast http://purl.obolibrary.org/obo/CL_0000550 polychromatophilic erythroblast A polychromatophilic erythroblast that is Lyg 76-high and is Kit-negative. http://purl.obolibrary.org/obo/CL_0002016 CD71-low, GlyA-positive polychromatic erythroblast http://purl.obolibrary.org/obo/CL_0000550 polychromatophilic erythroblast A polychromatiic erythroblast that is Gly-A-positive and CD71-low. http://purl.obolibrary.org/obo/GO_0060571 morphogenesis of an epithelial fold http://purl.obolibrary.org/obo/GO_0002009 morphogenesis of an epithelium The morphogenetic process in which an epithelial sheet bends along a linear axis. http://purl.obolibrary.org/obo/CL_0002017 Kit-negative, Ly-76 high orthochromatophilic erythroblasts http://purl.obolibrary.org/obo/CL_0000552 orthochromatic erythroblast An orthochromatophilic erythroblast that is ter119-high, CD71-low, and Kit-negative. http://purl.obolibrary.org/obo/CL_0002018 CD71-negative, GlyA-positive orthochromatic erythroblast http://purl.obolibrary.org/obo/CL_0000552 orthochromatic erythroblast An erythroblast that is GlyA-positive and CD71-negative. http://purl.obolibrary.org/obo/GO_0060632 regulation of microtubule-based movement http://purl.obolibrary.org/obo/GO_0032886 regulation of microtubule-based process Any process that modulates the rate, frequency, or extent of microtubule-based movement, the movement of organelles, other microtubules and other particles along microtubules, mediated by motor proteins. http://purl.obolibrary.org/obo/CL_0002019 Ly-76 high reticulocyte http://purl.obolibrary.org/obo/CL_0002422 enucleated reticulocyte A reticulocyte that is Ly76-high and is Kit-negative. http://purl.obolibrary.org/obo/GO_0060675 ureteric bud morphogenesis http://purl.obolibrary.org/obo/GO_0072171 mesonephric tubule morphogenesis The process in which the ureteric bud is generated and organized. http://purl.obolibrary.org/obo/CL_0002020 GlyA-positive reticulocytes http://purl.obolibrary.org/obo/CL_0002422 enucleated reticulocyte A reticulocyte that is GlyA-positive. http://purl.obolibrary.org/obo/CL_0002021 GlyA-positive erythrocyte http://purl.obolibrary.org/obo/CL_0000595 enucleate erythrocyte An enucleate erythrocyte that is GlyA-positive. http://purl.obolibrary.org/obo/GO_0060759 regulation of response to cytokine stimulus http://purl.obolibrary.org/obo/GO_0048583 regulation of response to stimulus Any process that modulates the rate, frequency, or extent of a response to cytokine stimulus. http://purl.obolibrary.org/obo/CL_0002022 Ly-76 high positive erythrocyte http://purl.obolibrary.org/obo/CL_0000595 enucleate erythrocyte An enucleate erythrocyte that is Lyg-76-high. http://purl.obolibrary.org/obo/GO_0060760 positive regulation of response to cytokine stimulus http://purl.obolibrary.org/obo/GO_0060759 regulation of response to cytokine stimulus Any process that increases the rate, frequency, or extent of a response to cytokine stimulus. http://purl.obolibrary.org/obo/CL_0002023 CD34-positive, CD41-positive, CD42-positive megakaryocyte progenitor cell http://purl.obolibrary.org/obo/CL_0000553 megakaryocyte progenitor cell A megakaroycotye progenitor cell that is CD34-positive, CD41-positive and CD42-positive on the cell surface. http://purl.obolibrary.org/obo/GO_0060761 negative regulation of response to cytokine stimulus http://purl.obolibrary.org/obo/GO_0060759 regulation of response to cytokine stimulus Any process that decreases the rate, frequency, or extent of a response to cytokine stimulus. http://purl.obolibrary.org/obo/CL_0002024 Kit-positive megakaryocyte progenitor cell http://purl.obolibrary.org/obo/CL_0000553 megakaryocyte progenitor cell A megakaryocyte progenitor cell that is Kit-positive, CD41-positive, CD9-positive, Sca-1-negative, IL7ralpha-negative, CD150-negative, and Fcgamma receptor II/III-low. http://purl.obolibrary.org/obo/GO_0060788 ectodermal placode formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The developmental process in which an ectodermal placode forms. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm. http://purl.obolibrary.org/obo/CL_0002025 CD34-positive, CD41-positive, CD42-negative megakaryocyte progenitor cell http://purl.obolibrary.org/obo/CL_0000553 megakaryocyte progenitor cell A megakaryocyte progenitor cell that is CD34-positive, CD41-positive, and CD42-negative. http://purl.obolibrary.org/obo/CL_0002026 CD34-negative, CD41-positive, CD42-positive megakaryocyte cell http://purl.obolibrary.org/obo/CL_0000556 megakaryocyte A megakaryocyte progenitor cell that is CD34-negative, CD41-positive and CD42-positive. http://purl.obolibrary.org/obo/GO_0060795 cell fate commitment involved in formation of primary germ layer http://purl.obolibrary.org/obo/GO_0045165 cell fate commitment The commitment of cells to specific cell fates of the endoderm, ectoderm, or mesoderm as a part of gastrulation. http://purl.obolibrary.org/obo/CL_0002027 CD9-positive, CD41-positive megakaryocyte cell http://purl.obolibrary.org/obo/CL_0000556 megakaryocyte A megakaryocyte cell with is CD9-positive and CD41-positive. http://purl.obolibrary.org/obo/GO_0060841 venous blood vessel development http://purl.obolibrary.org/obo/GO_0001568 blood vessel development The progression of the venous blood vessel over time from its initial formation to the mature structure. Venous blood vessels carry blood back to the heart after the capillary bed. http://purl.obolibrary.org/obo/CL_0002028 basophil mast progenitor cell http://purl.obolibrary.org/obo/CL_0002191 granulocytopoietic cell A cell type that can give rise to basophil and mast cells. This cell is CD34-positive, CD117-positive, CD125-positive, FceRIa-negative, and T1/ST2-negative, and expresses Gata-1, Gata-2, C/EBPa http://purl.obolibrary.org/obo/CL_0002029 Fc-epsilon RIalpha-low mast cell progenitor http://purl.obolibrary.org/obo/CL_0000831 mast cell progenitor A lineage-negative, Kit-positive, CD45-positive mast cell progenitor that is Fc-epsilon RIalpha-low. http://purl.obolibrary.org/obo/GO_0060900 embryonic camera-type eye formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The developmental process pertaining to the initial formation of a camera-type eye from unspecified neurectoderm. This process begins with the differentiation of cells that form the optic field and ends when the optic cup has attained its shape. http://purl.obolibrary.org/obo/CL_0002030 Fc-epsilon RIalpha-high basophil progenitor cell http://purl.obolibrary.org/obo/CL_0000613 basophil progenitor cell A lineage negative, Sca1-negative basophil progenitor cell that is Fc epsilon RIalpha-high. http://purl.obolibrary.org/obo/CL_0002031 hematopoietic lineage restricted progenitor cell http://purl.obolibrary.org/obo/CL_0008001 hematopoietic precursor cell A hematopoietic progenitor cell that is capable of developing into only one lineage of hematopoietic cells. http://purl.obolibrary.org/obo/GO_0060914 heart formation http://purl.obolibrary.org/obo/GO_0048645 animal organ formation The developmental process pertaining to the initial formation of the heart from unspecified parts. This process begins with the specific processes that contribute to the appearance of the heart field and the arrival of cardiac neural crest to the heart region. The process ends when the structural rudiment is recognizable. http://purl.obolibrary.org/obo/CL_0002032 hematopoietic oligopotent progenitor cell http://purl.obolibrary.org/obo/CL_0008001 hematopoietic precursor cell A hematopoietic oligopotent progenitor cell that has the ability to differentiate into limited cell types but lacks lineage cell markers and self renewal capabilities. http://purl.obolibrary.org/obo/GO_0060932 His-Purkinje system cell differentiation http://purl.obolibrary.org/obo/GO_0055007 cardiac muscle cell differentiation The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell of the His-Purkinje system. These cells form the fibers regulate cardiac muscle contraction in the ventricles. http://purl.obolibrary.org/obo/CL_0002033 short term hematopoietic stem cell http://purl.obolibrary.org/obo/CL_0001008 Kit and Sca1-positive hematopoietic stem cell A hematopoietic stem cell capable of rapid replenishment of myeloerythroid progenitors and limited self renewal capability. This cell is Kit-positive, Sca1-positive, CD34-positive, CD150-positive, and is Flt3-negative. http://purl.obolibrary.org/obo/CL_0002034 long term hematopoietic stem cell http://purl.obolibrary.org/obo/CL_0001008 Kit and Sca1-positive hematopoietic stem cell A hematopoietic stem cell with long term self renewal capability. This cell is Kit-positive, Sca1-positive, CD150-positive, CD90-low, CD34-negative and Flt3-negative. http://purl.obolibrary.org/obo/GO_0060973 cell migration involved in heart development http://purl.obolibrary.org/obo/GO_0016477 cell migration The orderly movement of a cell from one site to another that will contribute to the progression of the heart over time, from its initial formation, to the mature organ. http://purl.obolibrary.org/obo/CL_0002035 Slamf1-negative multipotent progenitor cell http://purl.obolibrary.org/obo/CL_0000837 hematopoietic multipotent progenitor cell A hematopoietic progenitor that has restricted self-renewal capability. Cell is Kit-positive, Ly6-positive, CD150-negative and Flt3-negative. http://purl.obolibrary.org/obo/CL_0002036 Slamf1-positive multipotent progenitor cell http://purl.obolibrary.org/obo/CL_0000837 hematopoietic multipotent progenitor cell A hematopoietic progenitor that has some limited self-renewal capability. Cells are lin-negative, Kit-positive, CD34-positive, and Slamf1-positive. http://purl.obolibrary.org/obo/GO_0060974 cell migration involved in heart formation http://purl.obolibrary.org/obo/GO_0060973 cell migration involved in heart development The orderly movement of a cell from one site to another that contribute to the formation of the heart. The initial heart structure is made up of mesoderm-derived heart progenitor cells and neural crest-derived cells. http://purl.obolibrary.org/obo/CL_0002037 CD2-positive, CD5-positive, CD44-positive alpha-beta intraepithelial T cell http://purl.obolibrary.org/obo/CL_0000793 CD4-positive, alpha-beta intraepithelial T cell Intraepithelial T cells with a memory phenotype of CD2-positive, CD5-positive, and CD44-positive. http://purl.obolibrary.org/obo/CL_0002038 T follicular helper cell http://purl.obolibrary.org/obo/CL_0020030 CD4-positive exhausted alpha-beta T cell A CD4-positive, CXCR5-positive, CCR7-negative alpha-beta T cell located in follicles of secondary lymph nodes that is BCL6-high, ICOS-high and PD1-high, and stimulates follicular B cells to undergo class-switching and antibody production. http://purl.obolibrary.org/obo/GO_0060976 coronary vasculature development http://purl.obolibrary.org/obo/GO_0001568 blood vessel development The process whose specific outcome is the progression of the blood vessels of the heart over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/CL_0002039 immature NK T cell stage I, mouse http://purl.obolibrary.org/obo/CL_0000914 immature NK T cell A CD24-high, CD4-low, CD8-low, CD44-negative, NK1.1-negative NK T cell. http://purl.obolibrary.org/obo/CL_0002040 immature NK T cell stage II, mouse http://purl.obolibrary.org/obo/CL_0000914 immature NK T cell A CD24-low, CD44-negative, NK1.1-negative NK T cell. http://purl.obolibrary.org/obo/GO_0060977 coronary vasculature morphogenesis http://purl.obolibrary.org/obo/GO_0048514 blood vessel morphogenesis The process in which the anatomical structures of blood vessels of the heart are generated and organized. The blood vessel is the vasculature carrying blood. http://purl.obolibrary.org/obo/CL_0002041 immature NK T cell stage III, mouse http://purl.obolibrary.org/obo/CL_0000914 immature NK T cell A CD24-low, CD44-positive, DX5-low, NK1.1-negative NK T cell. http://purl.obolibrary.org/obo/CL_0002042 immature NK T cell stage IV, mouse http://purl.obolibrary.org/obo/CL_0000914 immature NK T cell A CD24-low, CD44-positive, DX5-high, NK1.1-negative NK T cell. http://purl.obolibrary.org/obo/GO_0060993 kidney morphogenesis http://purl.obolibrary.org/obo/GO_0009887 animal organ morphogenesis Morphogenesis of a kidney. A kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine. http://purl.obolibrary.org/obo/CL_0002043 CD34-positive, CD38-negative multipotent progenitor cell http://purl.obolibrary.org/obo/CL_0000837 hematopoietic multipotent progenitor cell A hematopoietic multipotent progenitor cell that is CD34-positive, CD38-negative, CD45RA-negative, and CD90-negative. http://purl.obolibrary.org/obo/GO_0061008 hepaticobiliary system development http://purl.obolibrary.org/obo/GO_0048731 system development The progression of the hepaticobiliary system over time, from its formation to the mature structure. The hepaticobiliary system is responsible for metabolic and catabolic processing of small molecules absorbed from the blood or gut, hormones and serum proteins, detoxification, storage of glycogen, triglycerides, metals and lipid soluble vitamins and excretion of bile. Included are the synthesis of albumin, blood coagulation factors, complement, and specific binding proteins. http://purl.obolibrary.org/obo/CL_0002044 Kit-positive, integrin beta7-high basophil mast progenitor cell http://purl.obolibrary.org/obo/CL_0002028 basophil mast progenitor cell A basophil mast progenitor cell that is Beta-7 integrin-high, Kit-positive FcRgammaII/III-positive and Sca1-negative. http://purl.obolibrary.org/obo/GO_0061025 membrane fusion http://purl.obolibrary.org/obo/GO_0061024 membrane organization The membrane organization process that joins two lipid bilayers to form a single membrane. http://purl.obolibrary.org/obo/CL_0002045 fraction A pre-pro B cell http://purl.obolibrary.org/obo/CL_0000826 pro-B cell A pro-B cell that is CD45R/B220-positive, CD43-positive, HSA-low, BP-1-negative and Ly6c-negative. This cell type is also described as being lin-negative, AA4-positive, Kit-positive, IL7Ra-positive and CD45R-positive. http://purl.obolibrary.org/obo/GO_0061035 regulation of cartilage development http://purl.obolibrary.org/obo/GO_2000026 regulation of multicellular organismal development Any process that modulates the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate. http://purl.obolibrary.org/obo/CL_0002046 early pro-B cell http://purl.obolibrary.org/obo/CL_0000826 pro-B cell A pro-B cell that is CD22-positive, CD34-positive, CD38-positive and TdT-positive (has TdT activity). Pre-BCR is expressed on the cell surface. Cell is CD19-negative, CD20-negative, complement receptor type 2-negative and CD10-low. D-to-J recombination of the heavy chain occurs at this stage. http://purl.obolibrary.org/obo/GO_0061049 cell growth involved in cardiac muscle cell development http://purl.obolibrary.org/obo/GO_0048588 developmental cell growth The growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state. http://purl.obolibrary.org/obo/CL_0002047 fraction B precursor B cell http://purl.obolibrary.org/obo/CL_0002400 fraction B/C precursor B cell A precursor B cell that is CD45RA-positive, CD43-positive, CD24-positive and BP-1-negative. http://purl.obolibrary.org/obo/GO_0061053 somite development http://purl.obolibrary.org/obo/GO_0060429 epithelium development The progression of a somite from its initial formation to the mature structure. Somites are mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo. http://purl.obolibrary.org/obo/CL_0002048 late pro-B cell http://purl.obolibrary.org/obo/CL_0000817 precursor B cell A pre-B cell precursor is CD19-low, CD22-positive , CD34-positive, CD38-positive. http://purl.obolibrary.org/obo/GO_0061081 positive regulation of myeloid leukocyte cytokine production involved in immune response http://purl.obolibrary.org/obo/GO_0002720 positive regulation of cytokine production involved in immune response Any process that modulates the rate, frequency, or extent of the production of a cytokine that contributes to the immune response. http://purl.obolibrary.org/obo/CL_0002049 fraction C precursor B cell http://purl.obolibrary.org/obo/CL_0002400 fraction B/C precursor B cell A precursor B cell that is CD45R-positive, CD43-positive, CD24-positive, and BP-positive. Intracellularly expression of surrogate light chain, Rag1 and Rag2, TdT, occurs while there is no expression of mu heavy chain. http://purl.obolibrary.org/obo/GO_0061082 myeloid leukocyte cytokine production http://purl.obolibrary.org/obo/GO_0002367 cytokine production involved in immune response Any process that contributes to cytokine production by a myeloid cell. http://purl.obolibrary.org/obo/CL_0002050 fraction C' precursor B cell http://purl.obolibrary.org/obo/CL_0000817 precursor B cell A pre-BCR-positive precursor B cell that is CD24-high, CD25-positive, CD43-positive, CD45R-positive and BP-positive. http://purl.obolibrary.org/obo/GO_0061308 cardiac neural crest cell development involved in heart development http://purl.obolibrary.org/obo/GO_0014032 neural crest cell development The process aimed at the progression of a cardiac neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell that contributes to the development of the heart. http://purl.obolibrary.org/obo/CL_0002051 CD38-high pre-BCR positive cell http://purl.obolibrary.org/obo/CL_0000952 preBCR-positive large pre-B-II cell A pre-BCR positive B cell that is CD38-high. http://purl.obolibrary.org/obo/GO_0061309 cardiac neural crest cell development involved in outflow tract morphogenesis http://purl.obolibrary.org/obo/GO_0061308 cardiac neural crest cell development involved in heart development The process aimed at the progression of a cardiac neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell that contributes to the shaping of the outflow tract. http://purl.obolibrary.org/obo/CL_0002052 fraction D precursor B cell http://purl.obolibrary.org/obo/CL_0002400 fraction B/C precursor B cell A pre-B cell that is pre-BCR-negative, and the kappa- and lambda- light immunoglobulin light chain-negative, CD43-low, and is BP-1-positive, CD45R-positive and CD25-positive. This cell type is also described as being AA4-positive, IgM-negative, CD19-positive, CD43-low/negative, and HSA-positive. http://purl.obolibrary.org/obo/CL_0002053 CD22-positive, CD38-low small pre-B cell http://purl.obolibrary.org/obo/CL_0000954 small pre-B-II cell A small pre-B cell that is CD22-positive and CD38-low. http://purl.obolibrary.org/obo/GO_0061311 cell surface receptor signaling pathway involved in heart development http://purl.obolibrary.org/obo/GO_0007166 cell surface receptor signaling pathway The series of molecular signals initiated by a ligand the binding to its receptor on the surface of a cell, which contributes to the progression of the heart over time. http://purl.obolibrary.org/obo/CL_0002054 fraction E immature B cell http://purl.obolibrary.org/obo/CL_0000816 immature B cell An immature B cell that is IgM-positive, CD45R-positive, CD43-low, CD25-negative, and CD127-negative. This cell type has also been described as being AA4-positive, IgM-positive, CD19-positive, CD43-low/negative, and HSA-positive. http://purl.obolibrary.org/obo/GO_0061323 cell proliferation involved in heart morphogenesis http://purl.obolibrary.org/obo/GO_0008283 cell population proliferation The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to the shaping of the heart. http://purl.obolibrary.org/obo/CL_0002055 CD38-negative immature B cell http://purl.obolibrary.org/obo/CL_0000816 immature B cell An immature B cell that is CD38-negative, CD10-low, CD21-low, and CD22-high. http://purl.obolibrary.org/obo/GO_0061343 cell adhesion involved in heart morphogenesis http://purl.obolibrary.org/obo/GO_0007155 cell adhesion The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules that contributes to the shaping of the heart. http://purl.obolibrary.org/obo/CL_0002056 fraction F mature B cell http://purl.obolibrary.org/obo/CL_0000822 B-2 B cell A mature B cell subset originally defined as having being CD45R-positive, IgM-positive, IgD-positive and CD43-negative. Subsequent research demonstrated being CD21-positive and CD23-negative and CD93 negative. http://purl.obolibrary.org/obo/GO_0061384 heart trabecula morphogenesis http://purl.obolibrary.org/obo/GO_0061383 trabecula morphogenesis The process of shaping a trabecula in the heart. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue. http://purl.obolibrary.org/obo/CL_0002057 CD14-positive, CD16-negative classical monocyte http://purl.obolibrary.org/obo/CL_0001054 CD14-positive monocyte A classical monocyte that is CD14-positive, CD16-negative, CD64-positive, CD163-positive. http://purl.obolibrary.org/obo/GO_0061448 connective tissue development http://purl.obolibrary.org/obo/GO_0009888 tissue development The progression of a connective tissue over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/CL_0002058 Gr1-low non-classical monocyte http://purl.obolibrary.org/obo/CL_0002398 Gr1-positive, CD43-positive monocyte A resident monocyte that is Gr-1 low, CD43-positive, and CX3CR1-positive. http://purl.obolibrary.org/obo/GO_0061844 antimicrobial humoral immune response mediated by antimicrobial peptide http://purl.obolibrary.org/obo/GO_0019730 antimicrobial humoral response An immune response against microbes mediated by anti-microbial peptides in body fluid. http://purl.obolibrary.org/obo/CL_0002059 CD8-alpha-positive thymic conventional dendritic cell http://purl.obolibrary.org/obo/CL_0000941 thymic conventional dendritic cell A conventional thymic dendritic cell that is CD8-alpha-positive. http://purl.obolibrary.org/obo/CL_0002060 melanophage http://purl.obolibrary.org/obo/CL_0000864 tissue-resident macrophage A melanin-containing macrophage that obtains the pigment by phagocytosis of melanosomes. http://purl.obolibrary.org/obo/GO_0065005 protein-lipid complex assembly http://purl.obolibrary.org/obo/GO_0071825 protein-lipid complex organization The aggregation, arrangement and bonding together of proteins and lipids to form a protein-lipid complex. http://purl.obolibrary.org/obo/CL_0002061 T-helper 9 cell http://purl.obolibrary.org/obo/CL_0000492 CD4-positive helper T cell A T-helper cell that is characterized by secreting interleukin 9 and responding to helminth infections. This cell-type can derives from Th2 cells in the presence of TGF-beta and IL-4. Th2 cytokine production is surpressed. http://purl.obolibrary.org/obo/GO_0065008 regulation of biological quality http://purl.obolibrary.org/obo/GO_0065007 biological regulation Any process that modulates a qualitative or quantitative trait of a biological quality. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc. http://purl.obolibrary.org/obo/CL_0002062 pulmonary alveolar type 1 cell http://purl.obolibrary.org/obo/CL_0000322 pulmonary alveolar epithelial cell A squamous pulmonary alveolar epithelial cell that is flattened and branched. A pulmonary alveolar type 1 cell covers more than 98% of the alveolar surface. This large cell has thin (50-100 nm) cytoplasmic extensions to form the air-blood barrier essential for normal gas exchange. http://purl.obolibrary.org/obo/GO_0070227 lymphocyte apoptotic process http://purl.obolibrary.org/obo/GO_0071887 leukocyte apoptotic process Any apoptotic process in a lymphocyte, a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin. http://purl.obolibrary.org/obo/CL_0002063 pulmonary alveolar type 2 cell http://purl.obolibrary.org/obo/CL_0020029 cuboidal epithelial cell A pulmonary alveolar epithelial cell that modulates the fluid surrounding the alveolar epithelium by secreting and recycling surfactants via specialized organelles called alveolar lamellar bodies. This cell type also contributes to tissue repair and can differentiate after injury into a pulmonary alveolar type 1 cell. This cuboidal cell is thicker than squamous alveolar cells, has a rounded apical surface that projects above the level of the surrounding epithelium, and its free surface is covered by short microvilli. http://purl.obolibrary.org/obo/GO_0070228 regulation of lymphocyte apoptotic process http://purl.obolibrary.org/obo/GO_2000106 regulation of leukocyte apoptotic process Any process that modulates the occurrence or rate of lymphocyte death by apoptotic process. http://purl.obolibrary.org/obo/GO_0070229 negative regulation of lymphocyte apoptotic process http://purl.obolibrary.org/obo/GO_2000107 negative regulation of leukocyte apoptotic process Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte death by apoptotic process. http://purl.obolibrary.org/obo/CL_0002064 pancreatic acinar cell http://purl.obolibrary.org/obo/CL_1001599 pancreas exocrine glandular cell A secretory cell found in pancreatic acini that secretes digestive enzymes and mucins. This cell is a typical zymogenic cell, have a basal nucleus and basophilic cytoplasm consisting of regular arrays of granular endoplasmic reticulum with mitochondria and dense secretory granules. http://purl.obolibrary.org/obo/GO_0070230 positive regulation of lymphocyte apoptotic process http://purl.obolibrary.org/obo/GO_2000108 positive regulation of leukocyte apoptotic process Any process that activates or increases the frequency, rate or extent of lymphocyte death by apoptotic process. http://purl.obolibrary.org/obo/GO_0070252 actin-mediated cell contraction http://purl.obolibrary.org/obo/GO_0030048 actin filament-based movement The actin filament-based process in which cytoplasmic actin filaments slide past one another resulting in contraction of all or part of the cell body. http://purl.obolibrary.org/obo/CL_0002066 Feyrter cell http://purl.obolibrary.org/obo/CL_0000165 neuroendocrine cell A neuroendocrine cell found in the epithelium of the lungs and respiratory tract. This cell type is rounded or elliptical in shape, situated mainly in the basal part of the epithelium; regulates bronchial secretion, smooth muscle contraction, lobular growth, ciliary activity and chemoreception. Cell has an electron-lucent cytoplasm, contains numerous dense-cored vesicles with a clear halo between the core and the limiting membrane. http://purl.obolibrary.org/obo/GO_0070278 extracellular matrix constituent secretion http://purl.obolibrary.org/obo/GO_0032940 secretion by cell The controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell. http://purl.obolibrary.org/obo/CL_0002067 type A enteroendocrine cell http://purl.obolibrary.org/obo/CL_0000170 glucagon secreting cell An enteroendocrine cell that produces glucagon. http://purl.obolibrary.org/obo/GO_0070482 response to oxygen levels http://purl.obolibrary.org/obo/GO_0009628 response to abiotic stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of oxygen. http://purl.obolibrary.org/obo/CL_0002068 Purkinje myocyte http://purl.obolibrary.org/obo/CL_0002086 specialized cardiac myocyte Specialized cardiac myocyte that is subendocardially interspersed with the regular cardiac muscle cell. They are uninucleate cylindrical cells, associated end-to-end in long rows, continue from the node to the atrioventricular bundle; relatively short compared to ordinary myocytes but are nearly twice their diameter. http://purl.obolibrary.org/obo/GO_0070483 detection of hypoxia http://purl.obolibrary.org/obo/GO_0003032 detection of oxygen The series of events in which a stimulus indicating lowered oxygen tension is received by a cell and converted into a molecular signal. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level. http://purl.obolibrary.org/obo/CL_0002069 type II vestibular sensory cell http://purl.obolibrary.org/obo/CL_0000609 vestibular hair cell Mostly cylindrical, resemble Type 1 in their contents and the presence of a kinocilium and stereocilium apically; much greater variation in size, some almost span the entire thickness of the sensory epithelium, while others are smaller than Type 1; receive multiple efferent nerve boutons around their bases as well as afferent endings, which are small expansions rather than chalices. http://purl.obolibrary.org/obo/GO_0070586 cell-cell adhesion involved in gastrulation http://purl.obolibrary.org/obo/GO_0098609 cell-cell adhesion The attachment of one cell to another cell affecting gastrulation. http://purl.obolibrary.org/obo/GO_0070661 leukocyte proliferation http://purl.obolibrary.org/obo/GO_0008283 cell population proliferation The expansion of a leukocyte population by cell division. http://purl.obolibrary.org/obo/CL_0002070 type I vestibular sensory cell http://purl.obolibrary.org/obo/CL_0000609 vestibular hair cell Bottle-shaped with narrow neck; broad, rounded basal portion where nucleus is located; stereocilia and a single kinocilium is present apically; receive nerve bouton at their base from an afferent cup-shaped (chalice or calyx) nerve ending. http://purl.obolibrary.org/obo/GO_0070887 cellular response to chemical stimulus http://purl.obolibrary.org/obo/GO_0042221 response to chemical Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus. http://purl.obolibrary.org/obo/CL_0002071 enterocyte of epithelium of large intestine http://purl.obolibrary.org/obo/CL_0002253 epithelial cell of large intestine A columnar absorptive epithelial cell found in the epithelium of large intestine, specialized for water and electrolyte absorption. Unlike small intestinal enterocytes, those in the large intestine have fewer apical microvilli. http://purl.obolibrary.org/obo/GO_0070925 organelle assembly http://purl.obolibrary.org/obo/GO_0022607 cellular component assembly The aggregation, arrangement and bonding together of a set of components to form an organelle. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane. http://purl.obolibrary.org/obo/CL_0002072 nodal myocyte http://purl.obolibrary.org/obo/CL_0002086 specialized cardiac myocyte A specialized cardiac myocyte in the sinoatrial and atrioventricular nodes. The cell is slender and fusiform confined to the nodal center, circumferentially arranged around the nodal artery. http://purl.obolibrary.org/obo/GO_0071248 cellular response to metal ion http://purl.obolibrary.org/obo/GO_0010038 response to metal ion Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metal ion stimulus. http://purl.obolibrary.org/obo/CL_0002073 transitional myocyte http://purl.obolibrary.org/obo/CL_0002086 specialized cardiac myocyte Specialized cardiac myocyte which is in the internodal tract and atrioventricular node. The cell is more slender than ordinary atrial myocytes and has more myofibrils than nodal myocytes. http://purl.obolibrary.org/obo/GO_0071621 granulocyte chemotaxis http://purl.obolibrary.org/obo/GO_0097530 granulocyte migration The movement of a granulocyte in response to an external stimulus. http://purl.obolibrary.org/obo/CL_0002074 myocardial endocrine cell http://purl.obolibrary.org/obo/CL_0002086 specialized cardiac myocyte The myoendocrine cellis a specialized myocyte localized mainly in the right and left atrial appendages, and also scattered within other areas of the atria and along the conductive system in the ventricular septum. The most conspicuous feature distinguishing myoendocrine cells from other atrial myoctyes is the presence of membane-bounded secretory granules (these granules contain precursor of cardiodilatins or atrial natriuretic polypeptides). http://purl.obolibrary.org/obo/GO_0071674 mononuclear cell migration http://purl.obolibrary.org/obo/GO_0050900 leukocyte migration The movement of a mononuclear cell within or between different tissues and organs of the body. http://purl.obolibrary.org/obo/GO_0071695 anatomical structure maturation http://purl.obolibrary.org/obo/GO_0021700 developmental maturation A developmental process, independent of morphogenetic (shape) change, that is required for an anatomical structure to attain its fully functional state. http://purl.obolibrary.org/obo/CL_0002075 brush cell of tracheobronchial tree http://purl.obolibrary.org/obo/CL_0002204 tuft cell A rare type of columnar epithelial cell that is part of the tracheobronchial epithelium. This cell is characterized by a distinctive tuft of apical microvilli, which extends into the cytoplasm, and a pear-shaped morphology, broad at the base and tapering to a narrow apex. It plays vital roles in chemosensation, producing cytokines like IL-25, and enhancing mucociliary clearance through acetylcholine release to support mucus movement and airway defense. http://purl.obolibrary.org/obo/GO_0071709 membrane assembly http://purl.obolibrary.org/obo/GO_0022607 cellular component assembly The aggregation, arrangement and bonding together of a set of components to form a membrane. http://purl.obolibrary.org/obo/GO_0071887 leukocyte apoptotic process http://purl.obolibrary.org/obo/GO_0006915 apoptotic process Any apoptotic process in a leukocyte, an achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue. http://purl.obolibrary.org/obo/CL_0002076 endo-epithelial cell http://purl.obolibrary.org/obo/CL_0000066 epithelial cell An epithelial cell derived from endoderm. http://purl.obolibrary.org/obo/CL_0002077 ecto-epithelial cell http://purl.obolibrary.org/obo/CL_0000066 epithelial cell An epithelial cell derived from ectoderm. http://purl.obolibrary.org/obo/GO_0071897 DNA biosynthetic process http://purl.obolibrary.org/obo/GO_0006259 DNA metabolic process The biosynthetic process resulting in the formation of DNA. http://purl.obolibrary.org/obo/CL_0002078 meso-epithelial cell http://purl.obolibrary.org/obo/CL_0000066 epithelial cell Epithelial cell derived from mesoderm or mesenchyme. http://purl.obolibrary.org/obo/GO_0072001 renal system development http://purl.obolibrary.org/obo/GO_0048731 system development The process whose specific outcome is the progression of the renal system over time, from its formation to the mature structure. The renal system maintains fluid balance and contributes to electrolyte balance, acid/base balance, and disposal of nitrogenous waste products. In humans, the renal system comprises a pair of kidneys, a pair of ureters, urinary bladder, urethra, sphincter muscle and associated blood vessels. http://purl.obolibrary.org/obo/CL_0002079 pancreatic ductal cell http://purl.obolibrary.org/obo/CL_1001433 epithelial cell of exocrine pancreas Epithelial cell found in the ducts of the pancreas. This cell type contributes to the high luminal pH. http://purl.obolibrary.org/obo/GO_0072132 mesenchyme morphogenesis http://purl.obolibrary.org/obo/GO_0048729 tissue morphogenesis The process in which the anatomical structures of a mesenchymal tissue are generated and organized. A mesenchymal tissue is made up of loosely packed stellate cells. http://purl.obolibrary.org/obo/CL_0002080 pancreatic centro-acinar cell http://purl.obolibrary.org/obo/CL_1001433 epithelial cell of exocrine pancreas A cubodial epithelial cell that is continuous with the lining of intercalated ducts that drain the acinus. This cell type secretes a high pH solution to aid in activation of zymogens, and can differentiate into endocrine and exocrine pancreatic cell types. http://purl.obolibrary.org/obo/GO_0072164 mesonephric tubule development http://purl.obolibrary.org/obo/GO_0072163 mesonephric epithelium development The progression of a mesonephric tubule over time, from its initial formation to the mature structure. A mesonephric tubule is an epithelial tube that is part of the mesonephros. http://purl.obolibrary.org/obo/CL_0002081 type II cell of carotid body http://purl.obolibrary.org/obo/CL_0002256 supporting cell of carotid body This cell resembles a glia cell, express the glial marker S100 and act as a supporting cell to type I cell. This cell is located in a small cluster of type I and type II cells near the fork of the carotid artery. http://purl.obolibrary.org/obo/GO_0072175 epithelial tube formation http://purl.obolibrary.org/obo/GO_0035148 tube formation The developmental process pertaining to the initial formation of an epithelial tube. http://purl.obolibrary.org/obo/CL_0002082 type II cell of adrenal medulla http://purl.obolibrary.org/obo/CL_0000454 epinephrine secreting cell A chromaffin cell of the adrenal medulla that produces epinephrine. http://purl.obolibrary.org/obo/GO_0072215 regulation of metanephros development http://purl.obolibrary.org/obo/GO_0090183 regulation of kidney development Any process that modulates the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine. http://purl.obolibrary.org/obo/CL_0002083 type I cell of adrenal medulla http://purl.obolibrary.org/obo/CL_0000459 noradrenergic cell A chromaffin cell of the adrenal medulla that produces norepinephrine. http://purl.obolibrary.org/obo/CL_0002084 Boettcher cell http://purl.obolibrary.org/obo/CL_0002315 supporting cell of cochlea A Boettcher cell is a polyhedral cells on the basilar membrane of the cochlea, and is located beneath Claudius cells. A Boettcher cell is considered a supporting cell for the organ of Corti, and is present only in the lower turn of the cochlea. These cells interweave with each other, and project microvilli into the intercellular space. Because of their structural specialization, a Boettcher cell is believed to play a significant role in the function of the cochlea. They demonstrate high levels of calmodulin, and may be involved in mediating Ca(2+) regulation and ion transport. http://purl.obolibrary.org/obo/GO_0072217 negative regulation of metanephros development http://purl.obolibrary.org/obo/GO_0090185 negative regulation of kidney development Any process that decreases the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine. http://purl.obolibrary.org/obo/GO_0072283 metanephric renal vesicle morphogenesis http://purl.obolibrary.org/obo/GO_0072077 renal vesicle morphogenesis The process in which the anatomical structures of the metanephric renal vesicle are generated and organized. The renal vesicle is the primordial structure of the metanephric nephron epithelium, and is formed by the condensation of mesenchymal cells. http://purl.obolibrary.org/obo/CL_0002085 tanycyte http://purl.obolibrary.org/obo/CL_0000065 ependymal cell A specialized elongated ventricular ependymal cell with one or more processes that extend into the brain parenchyma or associated blood vessels where they contact blood vessel endothelial cells and/or neurons. These cells are found in the ventricles and circumventricular organs of the brain. They are involved in hormonal regulation, gatekeeping molecules between the bloodstream and cerebrospinal fluid, metabolic sensing, and regulating food intake. http://purl.obolibrary.org/obo/GO_0072330 monocarboxylic acid biosynthetic process http://purl.obolibrary.org/obo/GO_0046394 carboxylic acid biosynthetic process The chemical reactions and pathways resulting in the formation of monocarboxylic acids, any organic acid containing one carboxyl (-COOH) group. http://purl.obolibrary.org/obo/CL_0002086 specialized cardiac myocyte http://purl.obolibrary.org/obo/CL_0000746 cardiac muscle cell A cardiac myocyte that is an excitable cells in the myocardium, specifically in the conducting system of heart. http://purl.obolibrary.org/obo/GO_0072341 modified amino acid binding http://purl.obolibrary.org/obo/GO_0005488 binding Binding to a modified amino acid. http://purl.obolibrary.org/obo/GO_0072348 sulfur compound transport http://purl.obolibrary.org/obo/GO_0006810 transport The directed movement of compounds that contain sulfur, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/CL_0002087 nongranular leukocyte http://purl.obolibrary.org/obo/CL_0000738 leukocyte A leukocyte that lacks granules. http://purl.obolibrary.org/obo/CL_0002088 interstitial cell of Cajal http://purl.obolibrary.org/obo/CL_0000710 neurecto-epithelial cell This is a cell found in the gastrointestinal tract of mammals and serves as a pacemaker that triggers gut contraction. ICCs mediate inputs from the enteric nervous system to smooth muscle cells and are thought to be the cells from which gastrointestinal stromal tumors (GISTs) arise. http://purl.obolibrary.org/obo/GO_0072349 modified amino acid transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity Enables the transfer of modified amino acids from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0072593 reactive oxygen species metabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process The chemical reactions and pathways involving a reactive oxygen species, any molecules or ions formed by the incomplete one-electron reduction of oxygen. They contribute to the microbicidal activity of phagocytes, regulation of signal transduction and gene expression, and the oxidative damage to biopolymers. http://purl.obolibrary.org/obo/CL_0002089 group 2 innate lymphoid cell, mouse http://purl.obolibrary.org/obo/CL_0001069 group 2 innate lymphoid cell A group 2 innate lymphoid cell in the mouse capable of secreting IL-13 in response to a helminth infection. This cell is lineage-negative, ICOS-positive, IL1RL1-positive, IL7Ralpha-positive, and IL17Br-positive. http://purl.obolibrary.org/obo/GO_0080135 regulation of cellular response to stress http://purl.obolibrary.org/obo/GO_0080134 regulation of response to stress Any process that modulates the frequency, rate or extent of a cellular response to stress. Cellular response to stress is a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). http://purl.obolibrary.org/obo/CL_0002090 polar body http://purl.obolibrary.org/obo/CL_0000021 female germ cell One of two small cells formed by the first and second meiotic division of oocytes. http://purl.obolibrary.org/obo/CL_0002091 primary polar body http://purl.obolibrary.org/obo/CL_0002090 polar body A small cell formed by the first meiotic division of oocytes. http://purl.obolibrary.org/obo/GO_0090087 regulation of peptide transport http://purl.obolibrary.org/obo/GO_0051049 regulation of transport Any process that modulates the frequency, rate or extent of the directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/CL_0002092 bone marrow cell http://purl.obolibrary.org/obo/CL_0001035 bone cell A cell found in the bone marrow. This can include fibroblasts, macrophages, adipocytes, osteoblasts, osteoclasts, endothelial cells and hematopoietic cells. http://purl.obolibrary.org/obo/CL_0002093 secondary polar body http://purl.obolibrary.org/obo/CL_0002090 polar body A small cell formed by the second meiotic division of oocytes. In mammals, the second polar body may fail to form unless the ovum has been penetrated by a sperm cell. http://purl.obolibrary.org/obo/GO_0090171 chondrocyte morphogenesis http://purl.obolibrary.org/obo/GO_0000902 cell morphogenesis The process in which the structures of a chondrocyte are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a chondrocyte. http://purl.obolibrary.org/obo/CL_0002094 interstitial cell of ovary http://purl.obolibrary.org/obo/CL_0002132 stromal cell of ovary A cell that makes up the loose connective tissue of the ovary. http://purl.obolibrary.org/obo/GO_0090174 organelle membrane fusion http://purl.obolibrary.org/obo/GO_0061025 membrane fusion The joining of two lipid bilayers to form a single organelle membrane. http://purl.obolibrary.org/obo/CL_0002095 hilus cell of ovary http://purl.obolibrary.org/obo/CL_0002132 stromal cell of ovary A cell in the hilum of the ovary that produces androgens. http://purl.obolibrary.org/obo/GO_0090594 inflammatory response to wounding http://purl.obolibrary.org/obo/GO_0009611 response to wounding The immediate defensive reaction by vertebrate tissue to injury caused by chemical or physical agents. http://purl.obolibrary.org/obo/CL_0002096 internodal tract myocyte http://purl.obolibrary.org/obo/CL_0008009 transversely striated visceral muscle cell A specialised myocyte that lies between the sinoatrial node and the atrioventricular node and is involved in the conduction of electrical signals. http://purl.obolibrary.org/obo/GO_0090715 immunological memory formation process http://purl.obolibrary.org/obo/GO_0090713 immunological memory process Any immunological memory process that can contribute to the formation of immunological memory. http://purl.obolibrary.org/obo/CL_0002097 cortical cell of adrenal gland http://purl.obolibrary.org/obo/CL_1001601 adrenal gland glandular cell A cell of the adrenal cortex. Cell types include those that synthesize and secrete chemical derivatives (steroids) of cholesterol. http://purl.obolibrary.org/obo/GO_0097028 dendritic cell differentiation http://purl.obolibrary.org/obo/GO_1903131 mononuclear cell differentiation The process in which a precursor cell type acquires the specialized features of a dendritic cell. A dendritic cell is a leukocyte of dendritic lineage specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation. http://purl.obolibrary.org/obo/CL_0002098 regular cardiac myocyte http://purl.obolibrary.org/obo/CL_0000746 cardiac muscle cell A cardiac myocyte that is connected to other cardiac myocytes by transverse intercalated discs (GO:0014704) at a regular interval. http://purl.obolibrary.org/obo/GO_0097190 apoptotic signaling pathway http://purl.obolibrary.org/obo/GO_0007165 signal transduction The series of molecular signals which triggers the apoptotic death of a cell. The pathway starts with reception of a signal, and ends when the execution phase of apoptosis is triggered. http://purl.obolibrary.org/obo/CL_0002099 type I cell of adrenal cortex http://purl.obolibrary.org/obo/CL_0002097 cortical cell of adrenal gland A small, polyhedral, cell found in rounded groups or curved columns with deeply staining nuclei, scanty basophilic cytoplasm and a few lipid droplets. This cell in the zona glomerulosa produces mineralocorticoids. http://purl.obolibrary.org/obo/GO_0097191 extrinsic apoptotic signaling pathway http://purl.obolibrary.org/obo/GO_0097190 apoptotic signaling pathway The series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with either a ligand binding to a cell surface receptor, or a ligand being withdrawn from a cell surface receptor (e.g. in the case of signaling by dependence receptors), and ends when the execution phase of apoptosis is triggered. http://purl.obolibrary.org/obo/CL_0002100 regular interventricular cardiac myocyte http://purl.obolibrary.org/obo/CL_0002098 regular cardiac myocyte A regular cardiac myocyte of the interventricular region of the heart. http://purl.obolibrary.org/obo/CL_0002101 CD38-positive naive B cell http://purl.obolibrary.org/obo/CL_0000788 naive B cell A CD38-positive naive B cell is a mature B cell that has the phenotype CD38-positive, surface IgD-positive, surface IgM-positive, and CD27-negative, and that has not yet been activated by antigen in the periphery. http://purl.obolibrary.org/obo/GO_0097205 renal filtration http://purl.obolibrary.org/obo/GO_0003014 renal system process A renal system process in which fluid circulating through the body is filtered through a barrier system. http://purl.obolibrary.org/obo/CL_0002102 CD38-negative naive B cell http://purl.obolibrary.org/obo/CL_0000788 naive B cell A CD38-negative naive B cell is a mature B cell that has the phenotype CD38-negative, surface IgD-positive, surface IgM-positive, and CD27-negative, that has not yet been activated by antigen in the periphery. http://purl.obolibrary.org/obo/GO_0097367 carbohydrate derivative binding http://purl.obolibrary.org/obo/GO_0005488 binding Binding to a carbohydrate derivative. http://purl.obolibrary.org/obo/GO_0097529 myeloid leukocyte migration http://purl.obolibrary.org/obo/GO_0050900 leukocyte migration The movement of a myeloid leukocyte within or between different tissues and organs of the body. http://purl.obolibrary.org/obo/CL_0002103 IgG-positive double negative memory B cell http://purl.obolibrary.org/obo/CL_0000981 double negative memory B cell An IgG-positive double negative memory B cell is a double negative memory B cell with the phenotype IgG-positive, IgD-negative, and CD27-negative. http://purl.obolibrary.org/obo/GO_0097531 mast cell migration http://purl.obolibrary.org/obo/GO_0097529 myeloid leukocyte migration The movement of a mast cell within or between different tissues and organs of the body. http://purl.obolibrary.org/obo/CL_0002104 IgG-negative double negative memory B cell http://purl.obolibrary.org/obo/CL_0000981 double negative memory B cell An IgG-negative double negative memory B cell is a double negative memory B cell with the phenotype IgG-negative, IgD-negative, and CD27-negative. http://purl.obolibrary.org/obo/GO_0097642 calcitonin family receptor activity http://purl.obolibrary.org/obo/GO_0008528 G protein-coupled peptide receptor activity Combining with any member of the calcitonin family (e.g. adrenomedullin, adrenomedullin 2 (intermedin), amylin, calcitonin and calcitonin gene-related peptides (CGRPs)) to initiate a change in cell activity. http://purl.obolibrary.org/obo/CL_0002105 CD38-positive IgG memory B cell http://purl.obolibrary.org/obo/CL_0000979 IgG memory B cell A CD38-positive IgG memory B cell is a class switched memory B cell that expresses IgG on the cell surface with the phenotype CD38-positive and IgG-positive. http://purl.obolibrary.org/obo/GO_0098542 defense response to other organism http://purl.obolibrary.org/obo/GO_0051707 response to other organism Reactions triggered in response to the presence of another organism that act to protect the cell or organism from damage caused by that organism. http://purl.obolibrary.org/obo/CL_0002106 IgD-positive CD38-positive IgG memory B cell http://purl.obolibrary.org/obo/CL_0002105 CD38-positive IgG memory B cell An IgD-positive CD38-positive IgG memory B cell is a CD38-positive IgG-positive class switched memory B cell that has class switched and expresses IgD on the cell surface with the phenotype IgD-positive, CD38-positive, and IgG-positive. http://purl.obolibrary.org/obo/GO_0098588 bounding membrane of organelle http://purl.obolibrary.org/obo/GO_0031090 organelle membrane The lipid bilayer that forms the outer-most layer of an organelle. http://purl.obolibrary.org/obo/CL_0002107 IgD-negative CD38-positive IgG memory B cell http://purl.obolibrary.org/obo/CL_4052108 IgD-negative class switched memory B cell An IgD-negative CD38-positive IgG memory B cell is a CD38-positive IgG-positive that has class switched and lacks expression of IgD on the cell surface with the phenotype IgD-negative, CD38-positive, and IgG-positive. http://purl.obolibrary.org/obo/GO_0098657 import into cell http://purl.obolibrary.org/obo/GO_0006810 transport The directed movement of some substance from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis. http://purl.obolibrary.org/obo/CL_0002108 CD38-negative IgG memory B cell http://purl.obolibrary.org/obo/CL_4052108 IgD-negative class switched memory B cell A CD38-negative IgG memory B cell is a IgG-positive class switched memory B cell that has class switched and expresses IgG on the cell surface with the phenotype CD38-negative, IgD-negative, and IgG-positive. http://purl.obolibrary.org/obo/GO_0098773 skin epidermis development http://purl.obolibrary.org/obo/GO_0008544 epidermis development The process whose specific outcome is the progression of the skin epidermis over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/CL_0002109 B220-positive CD38-positive naive B cell http://purl.obolibrary.org/obo/CL_0002101 CD38-positive naive B cell A B220-positive CD38-positive naive B cell is a CD38-positive naive B cell that has the phenotype B220-positive, CD38-positive, surface IgD-positive, surface IgM-positive, and CD27-negative, and that has not yet been activated by antigen in the periphery. http://purl.obolibrary.org/obo/GO_0098796 membrane protein complex http://purl.obolibrary.org/obo/GO_0032991 protein-containing complex Any protein complex that is part of a membrane. http://purl.obolibrary.org/obo/CL_0002110 B220-low CD38-positive naive B cell http://purl.obolibrary.org/obo/CL_0002109 B220-positive CD38-positive naive B cell A B220-low CD38-positive naive B cell is a CD38-positive naive B cell that has the phenotype B220-low, CD38-positive, surface IgD-positive, surface IgM-positive, and CD27-negative, that has not yet been activated by antigen in the periphery. http://purl.obolibrary.org/obo/GO_0098797 plasma membrane protein complex http://purl.obolibrary.org/obo/GO_0098796 membrane protein complex Any protein complex that is part of the plasma membrane. http://purl.obolibrary.org/obo/GO_0098799 outer mitochondrial membrane protein complex http://purl.obolibrary.org/obo/GO_0098796 membrane protein complex Any protein complex that is part of the outer mitochondrial membrane. http://purl.obolibrary.org/obo/CL_0002111 CD38-negative unswitched memory B cell http://purl.obolibrary.org/obo/CL_0000970 unswitched memory B cell An CD38-negative unswitched memory B cell is an unswitched memory B cell that has the phenotype CD38-negative, IgD-positive, CD138-negative, and IgG-negative. http://purl.obolibrary.org/obo/GO_0098801 regulation of renal system process http://purl.obolibrary.org/obo/GO_0044057 regulation of system process Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by the renal system. http://purl.obolibrary.org/obo/CL_0002112 B220-positive CD38-negative unswitched memory B cell http://purl.obolibrary.org/obo/CL_0002111 CD38-negative unswitched memory B cell A B220-positive CD38-negative unswitched memory B cell is a CD38-negative unswitched memory B cell that has the phenotype B220-positive, CD38-negative, IgD-positive, CD138-negative, and IgG-negative. http://purl.obolibrary.org/obo/GO_0098813 nuclear chromosome segregation http://purl.obolibrary.org/obo/GO_0007059 chromosome segregation The process in which genetic material, in the form of nuclear chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. Nuclear chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles. http://purl.obolibrary.org/obo/CL_0002113 B220-low CD38-negative unswitched memory B cell http://purl.obolibrary.org/obo/CL_0002112 B220-positive CD38-negative unswitched memory B cell A B220-low CD38-negative unswitched memory B cell is a CD38-negative unswitched memory B cell that has the phenotype B220-low, CD38-negative, IgD-positive, CD138-negative, and IgG-negative. http://purl.obolibrary.org/obo/CL_0002114 CD38-positive unswitched memory B cell http://purl.obolibrary.org/obo/CL_0000970 unswitched memory B cell A CD38-positive unswitched memory B cell is an unswitched memory B cell that has the phenotype CD38-positive, IgD-positive, CD138-negative, and IgG-negative. http://purl.obolibrary.org/obo/GO_0098852 lytic vacuole membrane http://purl.obolibrary.org/obo/GO_0005774 vacuolar membrane The lipid bilayer surrounding a lytic vacuole and separating its contents from the cytoplasm of the cell. http://purl.obolibrary.org/obo/CL_0002115 B220-positive CD38-positive unswitched memory B cell http://purl.obolibrary.org/obo/CL_0002114 CD38-positive unswitched memory B cell A B220-positive CD38-positive unswitched memory B cell is a CD38-positive unswitched memory B cell that has the phenotype B220-positive, CD38-positive, IgD-positive, CD138-negative, and IgG-negative. http://purl.obolibrary.org/obo/GO_0098868 bone growth http://purl.obolibrary.org/obo/GO_0035265 organ growth The increase in size or mass of a bone that contributes to the shaping of that bone. http://purl.obolibrary.org/obo/GO_0098988 G protein-coupled glutamate receptor activity http://purl.obolibrary.org/obo/GO_0004930 G protein-coupled receptor activity Combining with glutamate and transmitting a signal from one side of the membrane to the other by activating an associated G-protein, initiating a change in cell activity. http://purl.obolibrary.org/obo/CL_0002116 B220-low CD38-positive unswitched memory B cell http://purl.obolibrary.org/obo/CL_0002115 B220-positive CD38-positive unswitched memory B cell A B220-low CD38-positive unswitched memory B cell is a CD38-positive unswitched memory B cell that has the phenotype B220-low, CD38-positive, IgD-positive, CD138-negative, and IgG-negative. http://purl.obolibrary.org/obo/CL_0002117 IgG-negative class switched memory B cell http://purl.obolibrary.org/obo/CL_4052108 IgD-negative class switched memory B cell A class switched memory B cell that lacks IgG on the cell surface. http://purl.obolibrary.org/obo/GO_0099512 supramolecular fiber http://purl.obolibrary.org/obo/GO_0099081 supramolecular polymer A polymer consisting of an indefinite number of protein or protein complex subunits that have polymerised to form a fiber-shaped structure. http://purl.obolibrary.org/obo/GO_0099513 polymeric cytoskeletal fiber http://purl.obolibrary.org/obo/GO_0099512 supramolecular fiber A component of the cytoskeleton consisting of a homo or heteropolymeric fiber constructed from an indeterminate number of protein subunits. http://purl.obolibrary.org/obo/CL_0002118 CD38-negative IgG-negative class switched memory B cell http://purl.obolibrary.org/obo/CL_0002117 IgG-negative class switched memory B cell A CD38-negative IgG-negative memory B cell is a IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype CD38-negative and IgG-negative. http://purl.obolibrary.org/obo/GO_0099612 protein localization to axon http://purl.obolibrary.org/obo/GO_0008104 intracellular protein localization A process in which a protein is transported to or maintained in a location within an axon. http://purl.obolibrary.org/obo/CL_0002119 CD38-positive IgG-negative class switched memory B cell http://purl.obolibrary.org/obo/CL_0002117 IgG-negative class switched memory B cell A CD38-positive IgG-negative memory B cell is an IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype CD38-positive and IgG-negative. http://purl.obolibrary.org/obo/GO_1900150 regulation of defense response to fungus http://purl.obolibrary.org/obo/GO_0031347 regulation of defense response Any process that modulates the frequency, rate or extent of defense response to fungus. http://purl.obolibrary.org/obo/CL_0002120 CD24-positive CD38-negative IgG-negative class switched memory B cell http://purl.obolibrary.org/obo/CL_0002118 CD38-negative IgG-negative class switched memory B cell An CD24-positive CD38-negative IgG-negative memory B cell is a CD38-negative IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype CD24-positive, CD38-negative, and IgG-negative. http://purl.obolibrary.org/obo/GO_1900424 regulation of defense response to bacterium http://purl.obolibrary.org/obo/GO_0031347 regulation of defense response Any process that modulates the frequency, rate or extent of defense response to bacterium. http://purl.obolibrary.org/obo/CL_0002121 CD24-negative CD38-negative IgG-negative class switched memory B cell http://purl.obolibrary.org/obo/CL_0002118 CD38-negative IgG-negative class switched memory B cell A CD24-negative CD38-negative IgG-negative memory B cell is a CD38-negative IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype CD24-negative, CD38-negative, and IgG-negative. http://purl.obolibrary.org/obo/GO_1900425 negative regulation of defense response to bacterium http://purl.obolibrary.org/obo/GO_0032102 negative regulation of response to external stimulus Any process that stops, prevents or reduces the frequency, rate or extent of defense response to bacterium. http://purl.obolibrary.org/obo/CL_0002122 B220-positive CD38-positive IgG-negative class switched memory B cell http://purl.obolibrary.org/obo/CL_0002119 CD38-positive IgG-negative class switched memory B cell A B220-positive CD38-positive IgG-negative memory B cell is a CD38-positive IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype B220-positive, CD38-positive, and IgG-negative. http://purl.obolibrary.org/obo/GO_1900426 positive regulation of defense response to bacterium http://purl.obolibrary.org/obo/GO_1900424 regulation of defense response to bacterium Any process that activates or increases the frequency, rate or extent of defense response to bacterium. http://purl.obolibrary.org/obo/GO_1901265 nucleoside phosphate binding http://purl.obolibrary.org/obo/GO_0005488 binding Binding to nucleoside phosphate. http://purl.obolibrary.org/obo/CL_0002123 B220-low CD38-positive IgG-negative class switched memory B cell http://purl.obolibrary.org/obo/CL_0002122 B220-positive CD38-positive IgG-negative class switched memory B cell A B220-low CD38-positive IgG-negative memory B cell is a CD38-positive IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype B220-low, CD38-positive, and IgG-positive. http://purl.obolibrary.org/obo/GO_1901363 heterocyclic compound binding http://purl.obolibrary.org/obo/GO_0036094 small molecule binding Binding to heterocyclic compound. http://purl.obolibrary.org/obo/CL_0002124 CD27-positive gamma-delta T cell http://purl.obolibrary.org/obo/CL_0000800 mature gamma-delta T cell A circulating gamma-delta T cell that is CD27-positive and capable of producing IFN-gamma. http://purl.obolibrary.org/obo/GO_1901605 alpha-amino acid metabolic process http://purl.obolibrary.org/obo/GO_0006520 amino acid metabolic process The chemical reactions and pathways involving an alpha-amino acid. http://purl.obolibrary.org/obo/CL_0002125 CD27-negative gamma-delta T cell http://purl.obolibrary.org/obo/CL_0000800 mature gamma-delta T cell A circulating gamma-delta T cell that expresses RORgamma(t), is CD27-negative and is capable of IL-17 secretion. http://purl.obolibrary.org/obo/GO_1901607 alpha-amino acid biosynthetic process http://purl.obolibrary.org/obo/GO_1901605 alpha-amino acid metabolic process The chemical reactions and pathways resulting in the formation of an alpha-amino acid. http://purl.obolibrary.org/obo/CL_0002126 CD25-positive, CD27-positive immature gamma-delta T cell http://purl.obolibrary.org/obo/CL_0000893 thymocyte A CD25-positive, CD27-positive immature gamma-delta T cell found in the thymus that has an immature phenotype (i.e. CD24-high, CD25-high, CD62L-high, CD44-high, CD2-low, CD5-low). http://purl.obolibrary.org/obo/GO_1901681 sulfur compound binding http://purl.obolibrary.org/obo/GO_0005488 binding Binding to a sulfur compound. http://purl.obolibrary.org/obo/GO_1901682 sulfur compound transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity Enables the transfer of a sulfur compound from one side of a membrane to the other. http://purl.obolibrary.org/obo/CL_0002127 innate effector T cell http://purl.obolibrary.org/obo/CL_0000911 effector T cell A T cell with a receptor of limited diversity that is capable of immediate effector functions upon stimulation. http://purl.obolibrary.org/obo/GO_1901700 response to oxygen-containing compound http://purl.obolibrary.org/obo/GO_0042221 response to chemical Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen-containing compound stimulus. http://purl.obolibrary.org/obo/CL_0002128 Tc17 cell http://purl.obolibrary.org/obo/CL_0000908 CD8-positive, alpha-beta cytokine secreting effector T cell A CD8-positive, alpha-beta T cell that has the phenotype CXCR3-negative, CCR6-positive, CCR5-high, CD45RA-negative, and capable of producing IL-17 and some IFNg. http://purl.obolibrary.org/obo/GO_1902105 regulation of leukocyte differentiation http://purl.obolibrary.org/obo/GO_1903706 regulation of hemopoiesis Any process that modulates the frequency, rate or extent of leukocyte differentiation. http://purl.obolibrary.org/obo/CL_0002129 regular atrial cardiac myocyte http://purl.obolibrary.org/obo/CL_0002098 regular cardiac myocyte Regular cardiac myocyte of a cardiac atrium. http://purl.obolibrary.org/obo/CL_0002130 regular interatrial cardiac myocyte http://purl.obolibrary.org/obo/CL_0002098 regular cardiac myocyte A cardiac myocyte of the interatrial region of the heart. http://purl.obolibrary.org/obo/GO_1902106 negative regulation of leukocyte differentiation http://purl.obolibrary.org/obo/GO_1903707 negative regulation of hemopoiesis Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte differentiation. http://purl.obolibrary.org/obo/CL_0002131 regular ventricular cardiac myocyte http://purl.obolibrary.org/obo/CL_0002098 regular cardiac myocyte Regular cardiac myocyte of a cardiac ventricle. http://purl.obolibrary.org/obo/GO_1902107 positive regulation of leukocyte differentiation http://purl.obolibrary.org/obo/GO_1903708 positive regulation of hemopoiesis Any process that activates or increases the frequency, rate or extent of leukocyte differentiation. http://purl.obolibrary.org/obo/CL_0002132 stromal cell of ovary http://purl.obolibrary.org/obo/CL_0000499 stromal cell A stomal cell of the ovary http://purl.obolibrary.org/obo/GO_1902275 regulation of chromatin organization http://purl.obolibrary.org/obo/GO_0051128 regulation of cellular component organization Any process that modulates the frequency, rate or extent of chromatin organization. http://purl.obolibrary.org/obo/CL_0002133 stromal cell of ovarian cortex http://purl.obolibrary.org/obo/CL_0002132 stromal cell of ovary A stromal cell of the ovarian cortex. http://purl.obolibrary.org/obo/GO_1902369 negative regulation of RNA catabolic process http://purl.obolibrary.org/obo/GO_0009895 negative regulation of catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of RNA catabolic process. http://purl.obolibrary.org/obo/CL_0002134 stromal cell of ovarian medulla http://purl.obolibrary.org/obo/CL_0002132 stromal cell of ovary A stromal cell of the ovarian medulla. http://purl.obolibrary.org/obo/GO_1902494 catalytic complex http://purl.obolibrary.org/obo/GO_0032991 protein-containing complex A protein complex which is capable of catalytic activity. http://purl.obolibrary.org/obo/CL_0002135 nonkeratinized cell of epidermis http://purl.obolibrary.org/obo/CL_0000362 epidermal cell Epidermal cells that do not contain keratin. Cell type is usually associated with moist epidermal tissues. http://purl.obolibrary.org/obo/GO_1902692 regulation of neuroblast proliferation http://purl.obolibrary.org/obo/GO_2000177 regulation of neural precursor cell proliferation Any process that modulates the frequency, rate or extent of neuroblast proliferation. http://purl.obolibrary.org/obo/CL_0002136 type II cell of adrenal cortex http://purl.obolibrary.org/obo/CL_0002097 cortical cell of adrenal gland A cell in the zona fasciculata that produce glucocorticoids, e.g cortisol. http://purl.obolibrary.org/obo/GO_1902742 apoptotic process involved in development http://purl.obolibrary.org/obo/GO_0006915 apoptotic process Any apoptotic process that is involved in anatomical structure development. http://purl.obolibrary.org/obo/CL_0002137 type III cell of adrenal cortex http://purl.obolibrary.org/obo/CL_0002097 cortical cell of adrenal gland A cell in the zona reticularis that produce sex hormones. http://purl.obolibrary.org/obo/GO_1903010 regulation of bone development http://purl.obolibrary.org/obo/GO_2000026 regulation of multicellular organismal development Any process that modulates the frequency, rate or extent of bone development. http://purl.obolibrary.org/obo/CL_0002138 endothelial cell of lymphatic vessel http://purl.obolibrary.org/obo/CL_0002139 endothelial cell of vascular tree A endothelial cell of a lymphatic vessel. The border of the oak leaf-shaped endothelial cell of initial lymphatics are joined by specialized buttons. The discontinuous feature of buttons distinguishes them from zippers in collecting lymphatics, but both types of junctions are composed of proteins typical of adherens junctions and tight junctions found in the endothelium of blood vessels. Buttons seal the sides of flaps of the oak leaf-shaped endothelial cell, leaving open the tips of flaps as routes for fluid entry without disassembly and reformation of intercellular junctions. http://purl.obolibrary.org/obo/GO_1903046 meiotic cell cycle process http://purl.obolibrary.org/obo/GO_0022414 reproductive process A process that is part of the meiotic cell cycle. http://purl.obolibrary.org/obo/GO_1903047 mitotic cell cycle process http://purl.obolibrary.org/obo/GO_0022402 cell cycle process A process that is part of the mitotic cell cycle. http://purl.obolibrary.org/obo/CL_0002139 endothelial cell of vascular tree http://purl.obolibrary.org/obo/CL_0000115 endothelial cell An endothelial cell of the vascular tree, which includes blood vessels and lymphatic vessels. http://purl.obolibrary.org/obo/GO_1903053 regulation of extracellular matrix organization http://purl.obolibrary.org/obo/GO_0051128 regulation of cellular component organization Any process that modulates the frequency, rate or extent of extracellular matrix organization. http://purl.obolibrary.org/obo/GO_1903054 negative regulation of extracellular matrix organization http://purl.obolibrary.org/obo/GO_0051129 negative regulation of cellular component organization Any process that stops, prevents or reduces the frequency, rate or extent of extracellular matrix organization. http://purl.obolibrary.org/obo/CL_0002140 skin sebocyte http://purl.obolibrary.org/obo/CL_0000622 acinar cell An acinar cell that is part of a skin sebaceous gland. This cell produces and secretes sebum into hair follicles. http://purl.obolibrary.org/obo/GO_1903055 positive regulation of extracellular matrix organization http://purl.obolibrary.org/obo/GO_0051130 positive regulation of cellular component organization Any process that activates or increases the frequency, rate or extent of extracellular matrix organization. http://purl.obolibrary.org/obo/CL_0002141 active chief cell of parathyroid gland http://purl.obolibrary.org/obo/CL_0000446 chief cell of parathyroid gland A parathyroid chief cell that is actively secreting hormone. Have large Golgi complexes with numerous vesicles and small membrane-bound granules; secretory granules are rare, cytoplasmic glycogen sparse, much of the cytoplasm being occupied by flat sacs of granular endoplasmic reticulum in parallel arrays; in normal humans, inactive chief cells outnumber active chief cells in a ratio of 3-5:1 http://purl.obolibrary.org/obo/GO_1903409 reactive oxygen species biosynthetic process http://purl.obolibrary.org/obo/GO_0072593 reactive oxygen species metabolic process The chemical reactions and pathways resulting in the formation of reactive oxygen species, any molecules or ions formed by the incomplete one-electron reduction of oxygen. http://purl.obolibrary.org/obo/CL_0002142 dark cell of eccrine sweat gland http://purl.obolibrary.org/obo/CL_1000448 epithelial cell of sweat gland A cell pyramidal in shape, with their broad ends facing and forming the greater extent of the lining of the main lumen. Secretes glycoproteins associated with mucus. http://purl.obolibrary.org/obo/GO_1903530 regulation of secretion by cell http://purl.obolibrary.org/obo/GO_0051046 regulation of secretion Any process that modulates the frequency, rate or extent of secretion by cell. http://purl.obolibrary.org/obo/GO_1903531 negative regulation of secretion by cell http://purl.obolibrary.org/obo/GO_1903530 regulation of secretion by cell Any process that stops, prevents or reduces the frequency, rate or extent of secretion by cell. http://purl.obolibrary.org/obo/CL_0002143 dark chief cell of parathyroid gland http://purl.obolibrary.org/obo/CL_0000446 chief cell of parathyroid gland A chief cell that is smaller than light chief cells and has a smaller and darker nucleus and a finely granular cytoplasm with many granules. http://purl.obolibrary.org/obo/GO_1903532 positive regulation of secretion by cell http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the frequency, rate or extent of secretion by cell. http://purl.obolibrary.org/obo/CL_0002144 capillary endothelial cell http://purl.obolibrary.org/obo/CL_2000008 microvascular endothelial cell An endothelial cell found in capillaries. http://purl.obolibrary.org/obo/GO_1903578 regulation of ATP metabolic process http://purl.obolibrary.org/obo/GO_1900542 regulation of purine nucleotide metabolic process Any process that modulates the frequency, rate or extent of ATP metabolic process. http://purl.obolibrary.org/obo/CL_0002145 multiciliated columnar cell of tracheobronchial tree http://purl.obolibrary.org/obo/CL_4030034 respiratory tract multiciliated cell A multi-ciliated epithelial cell located in the trachea and bronchi, characterized by a columnar shape and motile cilia on its apical surface. These cilia facilitate mucociliary clearance by moving mucus and trapped particles toward the pharynx. http://purl.obolibrary.org/obo/GO_1904746 negative regulation of apoptotic process involved in development http://purl.obolibrary.org/obo/GO_1904748 regulation of apoptotic process involved in development Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in development. http://purl.obolibrary.org/obo/CL_0002146 clear cell of eccrine sweat gland http://purl.obolibrary.org/obo/CL_1000448 epithelial cell of sweat gland A sweat producing cell of eccrine sweat glands. Pyramidal in shape, with its base resting on the basal lamina or myoepitheliocytes, and its microvillus-covered apical plasma membrane line up the intercellular canaliculi. Cell is not stained by hematoxylin or eosin. http://purl.obolibrary.org/obo/GO_1904747 positive regulation of apoptotic process involved in development http://purl.obolibrary.org/obo/GO_0043065 positive regulation of apoptotic process Any process that activates or increases the frequency, rate or extent of apoptotic process involved in development. http://purl.obolibrary.org/obo/CL_0002147 clear chief cell of parathyroid gland http://purl.obolibrary.org/obo/CL_0000446 chief cell of parathyroid gland A chief cell of parathyroid glands that does not stain with hematoxylin or eosin. This cell is larger, has a larger nucleus and fewer secretory granules than dark chief cells. http://purl.obolibrary.org/obo/GO_1904748 regulation of apoptotic process involved in development http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of apoptotic process involved in development. http://purl.obolibrary.org/obo/GO_1905039 carboxylic acid transmembrane transport http://purl.obolibrary.org/obo/GO_0055085 transmembrane transport The process in which carboxylic acid is transported across a membrane. http://purl.obolibrary.org/obo/CL_0002148 dental pulp cell http://purl.obolibrary.org/obo/CL_0002320 connective tissue cell A cell found within the dental pulp. http://purl.obolibrary.org/obo/GO_1905145 cellular response to acetylcholine http://purl.obolibrary.org/obo/GO_1901701 cellular response to oxygen-containing compound Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetylcholine stimulus. http://purl.obolibrary.org/obo/CL_0002149 epithelial cell of uterus http://purl.obolibrary.org/obo/CL_0002078 meso-epithelial cell An epithelial cell of the uterus. This cell has a mesodermal origin. http://purl.obolibrary.org/obo/CL_0002150 epithelioid macrophage http://purl.obolibrary.org/obo/CL_0000235 macrophage Epithelioid macrophage is an activated macrophage that resembles an epithelial cell with finely granular, pale eosinophilic cytoplasm and central, ovoid nucleus (oval or elongate). This cell type is able to merge into one another to form aggregates. The presence of such aggregates may characterize some pathologic conditions, mainly granulomatous inflammation. http://purl.obolibrary.org/obo/GO_1905330 regulation of morphogenesis of an epithelium http://purl.obolibrary.org/obo/GO_0022603 regulation of anatomical structure morphogenesis Any process that modulates the frequency, rate or extent of morphogenesis of an epithelium. http://purl.obolibrary.org/obo/GO_1905331 negative regulation of morphogenesis of an epithelium http://purl.obolibrary.org/obo/GO_1905330 regulation of morphogenesis of an epithelium Any process that stops, prevents or reduces the frequency, rate or extent of morphogenesis of an epithelium. http://purl.obolibrary.org/obo/CL_0002151 late promyelocyte http://purl.obolibrary.org/obo/CL_0000836 promyelocyte A promyelocyte that is considerably smaller, with more condensed chromatin, and nucleoli are no longer conspicuous. http://purl.obolibrary.org/obo/GO_1990234 transferase complex http://purl.obolibrary.org/obo/GO_1902494 catalytic complex A protein complex capable of catalyzing the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). http://purl.obolibrary.org/obo/CL_0002152 columnar cell of endocervix http://purl.obolibrary.org/obo/CL_0002535 epithelial cell of cervix A simple columnar epithelial cell located in the endocervix. http://purl.obolibrary.org/obo/CL_0002153 corneocyte http://purl.obolibrary.org/obo/CL_0000311 keratin accumulating cell The dead keratin-filled squamous cell of the stratum corneum. This cell type lacks a nucleus. http://purl.obolibrary.org/obo/GO_1990845 adaptive thermogenesis http://purl.obolibrary.org/obo/GO_0001659 temperature homeostasis The regulated production of heat in response to short term environmental changes, such as stress, diet or reduced temperature. http://purl.obolibrary.org/obo/CL_0002154 early promyelocyte http://purl.obolibrary.org/obo/CL_0000836 promyelocyte A promyelocyte with a nucleus that is indented and contains more marginated heterochromatin compared to its precursor cell (myeloblast); cytoplasm is deeply basophilic and contains numerous mitochondria and meandering cysternae of endoplasmic reticulum; largest of the granulocyte lineages. http://purl.obolibrary.org/obo/GO_2000026 regulation of multicellular organismal development http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of multicellular organismal development. http://purl.obolibrary.org/obo/GO_2000027 regulation of animal organ morphogenesis http://purl.obolibrary.org/obo/GO_0022603 regulation of anatomical structure morphogenesis Any process that modulates the frequency, rate or extent of animal organ morphogenesis. http://purl.obolibrary.org/obo/CL_0002155 echinocyte http://purl.obolibrary.org/obo/CL_0000595 enucleate erythrocyte A crenated erythrocyte with 30+ crenations, bumps or spurs that are the result of damage due to age or disease. http://purl.obolibrary.org/obo/GO_2000114 regulation of establishment of cell polarity http://purl.obolibrary.org/obo/GO_0032878 regulation of establishment or maintenance of cell polarity Any process that modulates the frequency, rate or extent of establishment of cell polarity. http://purl.obolibrary.org/obo/CL_0002157 endosteal cell http://purl.obolibrary.org/obo/CL_0002078 meso-epithelial cell A cell type that makes up the highly vascular membrane lining the marrow cavity of long bones. http://purl.obolibrary.org/obo/GO_2000136 regulation of cell proliferation involved in heart morphogenesis http://purl.obolibrary.org/obo/GO_0042127 regulation of cell population proliferation Any process that modulates the frequency, rate or extent of cell proliferation involved in heart morphogenesis. http://purl.obolibrary.org/obo/CL_0002158 external epithelial cell of tympanic membrane http://purl.obolibrary.org/obo/CL_0002159 general ecto-epithelial cell Epithelial cell found on the external side of the tympanic membrane http://purl.obolibrary.org/obo/GO_2000137 negative regulation of cell proliferation involved in heart morphogenesis http://purl.obolibrary.org/obo/GO_0008285 negative regulation of cell population proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of cell proliferation involved in heart morphogenesis. http://purl.obolibrary.org/obo/CL_0002159 general ecto-epithelial cell http://purl.obolibrary.org/obo/CL_0002077 ecto-epithelial cell Epithelial cells derived from general body ectoderm and ectoderm placodes. http://purl.obolibrary.org/obo/GO_2000138 positive regulation of cell proliferation involved in heart morphogenesis http://purl.obolibrary.org/obo/GO_2000136 regulation of cell proliferation involved in heart morphogenesis Any process that activates or increases the frequency, rate or extent of cell proliferation involved in heart morphogenesis. http://purl.obolibrary.org/obo/CL_0002160 basal external epithelial cell of tympanic membrane http://purl.obolibrary.org/obo/CL_0002158 external epithelial cell of tympanic membrane A cell type found in the basal epithelial layer on the external side of the tympanic membrane. Cell type is flattened with intracellular spaces of variable dimensions. http://purl.obolibrary.org/obo/GO_2000179 positive regulation of neural precursor cell proliferation http://purl.obolibrary.org/obo/GO_2000177 regulation of neural precursor cell proliferation Any process that activates or increases the frequency, rate or extent of neural precursor cell proliferation. http://purl.obolibrary.org/obo/CL_0002161 superficial external epithelial cell of tympanic membrane http://purl.obolibrary.org/obo/CL_0002158 external epithelial cell of tympanic membrane A cell type found on the superficial layer of the external side of the tympanic membrane. This cell-type lacks a nucleus. http://purl.obolibrary.org/obo/GO_2000648 positive regulation of stem cell proliferation http://purl.obolibrary.org/obo/GO_0072091 regulation of stem cell proliferation Any process that activates or increases the frequency, rate or extent of stem cell proliferation. http://purl.obolibrary.org/obo/CL_0002162 internal epithelial cell of tympanic membrane http://purl.obolibrary.org/obo/CL_0002076 endo-epithelial cell An extremely flattened cell type found on the inner side of the tympanic membrane. The surface of this cell type carries sparse pleomorphic microvilli that are more common near the junctional zones. http://purl.obolibrary.org/obo/GO_2000696 regulation of epithelial cell differentiation involved in kidney development http://purl.obolibrary.org/obo/GO_0030856 regulation of epithelial cell differentiation Any process that modulates the frequency, rate or extent of epithelial cell differentiation involved in kidney development. http://purl.obolibrary.org/obo/CL_0002163 internal pillar cell of cochlea http://purl.obolibrary.org/obo/CL_1000191 pillar cell A rod-shpaed cell that forms a single row adjacent to and supporting the inner hair cells. http://purl.obolibrary.org/obo/GO_2000697 negative regulation of epithelial cell differentiation involved in kidney development http://purl.obolibrary.org/obo/GO_2000696 regulation of epithelial cell differentiation involved in kidney development Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell differentiation involved in kidney development. http://purl.obolibrary.org/obo/CL_0002164 external pillar cell of cochlea http://purl.obolibrary.org/obo/CL_1000191 pillar cell A rod-shaped cell found in 3 or 4 rows that lie adjacent to and support the outer hair cells. http://purl.obolibrary.org/obo/CL_0002165 phalangeal cell http://purl.obolibrary.org/obo/CL_0002490 organ of Corti supporting cell A supporting cell that is attached to the basement membrane and forms rows that support the hair cells. http://purl.obolibrary.org/obo/GO_2000793 cell proliferation involved in heart valve development http://purl.obolibrary.org/obo/GO_0008283 cell population proliferation Any cell proliferation that is involved in heart valve development. http://purl.obolibrary.org/obo/CL_0002166 epithelial cell of Malassez http://purl.obolibrary.org/obo/CL_0002159 general ecto-epithelial cell An epithelial cell that remains from the disintegration of the epithelial root sheath involved in the development of teeth. http://purl.obolibrary.org/obo/GO_2000826 regulation of heart morphogenesis http://purl.obolibrary.org/obo/GO_2000027 regulation of animal organ morphogenesis Any process that modulates the frequency, rate or extent of heart morphogenesis. http://purl.obolibrary.org/obo/CL_0002167 olfactory epithelial cell http://purl.obolibrary.org/obo/CL_0002631 epithelial cell of upper respiratory tract A specialized cell involved in sensory perception of smell. http://purl.obolibrary.org/obo/GO_2000858 regulation of aldosterone secretion http://purl.obolibrary.org/obo/GO_2000855 regulation of mineralocorticoid secretion Any process that modulates the frequency, rate or extent of aldosterone secretion. http://purl.obolibrary.org/obo/GO_2001141 regulation of RNA biosynthetic process http://purl.obolibrary.org/obo/GO_0051252 regulation of RNA metabolic process Any process that modulates the frequency, rate or extent of RNA biosynthetic process. http://purl.obolibrary.org/obo/CL_0002168 border cell of cochlea http://purl.obolibrary.org/obo/CL_0002315 supporting cell of cochlea A border cell is a slender columnar cell on the medial portion of the basilar membrane. http://purl.obolibrary.org/obo/CL_0002169 basal cell of olfactory epithelium http://purl.obolibrary.org/obo/CL_0002167 olfactory epithelial cell An epithelial cell located on the basal lamina of the olfactory epithelium. http://purl.obolibrary.org/obo/GO_0019093 mitochondrial RNA localization http://purl.obolibrary.org/obo/GO_0006403 RNA localization Any process in which mitochondrial RNA is transported to, or maintained in, a specific location. http://purl.obolibrary.org/obo/CL_0002170 keratinized cell of the oral mucosa http://purl.obolibrary.org/obo/CL_0002336 buccal mucosa cell A keratinized cell located in the hard palate or gingiva. http://purl.obolibrary.org/obo/GO_0019215 intermediate filament binding http://purl.obolibrary.org/obo/GO_0005488 binding Binding to an intermediate filament, a distinct elongated structure, characteristically 10 nm in diameter, that occurs in the cytoplasm of higher eukaryotic cells. Intermediate filaments form a fibrous system, composed of chemically heterogeneous subunits and involved in mechanically integrating the various components of the cytoplasmic space. http://purl.obolibrary.org/obo/CL_0002171 globose cell of olfactory epithelium http://purl.obolibrary.org/obo/CL_0002169 basal cell of olfactory epithelium A rounded or elliptical epithelial cell, with pale-staining open face nucleus and pale cytoplasm rich in free ribosomes and clusters of centrioles; form a distinct basal zone spaced slightly from the basal surface of the epithelium. http://purl.obolibrary.org/obo/GO_0019216 regulation of lipid metabolic process http://purl.obolibrary.org/obo/GO_0080090 regulation of primary metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving lipids. http://purl.obolibrary.org/obo/CL_0002172 interdental cell of cochlea http://purl.obolibrary.org/obo/CL_0002315 supporting cell of cochlea A long, spindle-shaped supporting cells arranged in parallel rows that secretes components of the tectorial membrane and potassium ions into the endolymph. http://purl.obolibrary.org/obo/CL_0002173 extraglomerular mesangial cell http://purl.obolibrary.org/obo/CL_1000618 juxtaglomerular complex cell A cell that is a specialized type of pericyte providing structural support for the capillary loops of kidney. A flat, elongated cell with extensive fine cytoplasmic processes found outside the kidney glomerulus near the macula densa and bound laterally by afferent and efferent arterioles. Being phagocytic, this cell participates in the continuous turnover of the basal lamina by removing its outer portion containing residues of filtration, while the lamina is renewed on its inner surface by the endothelial cells. http://purl.obolibrary.org/obo/GO_0019226 transmission of nerve impulse http://purl.obolibrary.org/obo/GO_0050877 nervous system process The neurological system process in which a signal is transmitted through the nervous system by a combination of action potential propagation and synaptic transmission. http://purl.obolibrary.org/obo/GO_0019228 neuronal action potential http://purl.obolibrary.org/obo/GO_0001508 action potential An action potential that occurs in a neuron. http://purl.obolibrary.org/obo/CL_0002174 follicular cell of ovary http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell A cell within the follicle of an ovary. http://purl.obolibrary.org/obo/GO_0019230 proprioception http://purl.obolibrary.org/obo/GO_0007600 sensory perception The series of events by which an organism senses the position, location, orientation, and movement of the body and its parts. Proprioception is mediated by proprioceptors, sensory nerve terminals found in muscles, tendons, and joint capsules, which give information concerning movements and position of the body. The receptors in the labyrinth are sometimes also considered proprioceptors. http://purl.obolibrary.org/obo/CL_0002175 primary follicular cell of ovary http://purl.obolibrary.org/obo/CL_0002174 follicular cell of ovary A cell within the primary follicle of the ovary. http://purl.obolibrary.org/obo/GO_0019233 sensory perception of pain http://purl.obolibrary.org/obo/GO_0007600 sensory perception The series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal. A painful stimulus is any physical or chemical event that has the potential to cause tissue damage (actual or perceived) and activates the nociceptive system. http://purl.obolibrary.org/obo/CL_0002176 secondary follicular cell of ovary http://purl.obolibrary.org/obo/CL_0002174 follicular cell of ovary A cell of a secondary follicile within the ovary. http://purl.obolibrary.org/obo/CL_0002177 folliculostellate cell of pars distalis of adenohypophysis http://purl.obolibrary.org/obo/CL_0000710 neurecto-epithelial cell A supporting cell of the anterior pituitary gland involved in trophic and catabolic processes; expresses a broad spectrum of cytokeratins indicative of their epithelial nature. http://purl.obolibrary.org/obo/GO_0019336 phenol-containing compound catabolic process http://purl.obolibrary.org/obo/GO_0009056 catabolic process The chemical reactions and pathways resulting in the breakdown of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring. http://purl.obolibrary.org/obo/CL_0002178 epithelial cell of stomach http://purl.obolibrary.org/obo/CL_0002251 epithelial cell of alimentary canal An epithelial cell found in the lining of the stomach. http://purl.obolibrary.org/obo/GO_0019377 glycolipid catabolic process http://purl.obolibrary.org/obo/GO_1901136 carbohydrate derivative catabolic process The chemical reactions and pathways resulting in the breakdown of glycolipid, a class of 1,2-di-O-acylglycerols joined at oxygen 3 by a glycosidic linkage to a carbohydrate part (usually a mono-, di- or tri-saccharide). http://purl.obolibrary.org/obo/CL_0002179 foveolar cell of stomach http://purl.obolibrary.org/obo/CL_0002180 mucous cell of stomach A simple columnar cell that populates the entire luminal surface including the gastric pits. This cell types secrete mucus to form a thick protective, lubricant layer over the gastric wall. http://purl.obolibrary.org/obo/CL_0002180 mucous cell of stomach http://purl.obolibrary.org/obo/CL_0002178 epithelial cell of stomach An epithelial cell of the stomach. This cell produces mucous. http://purl.obolibrary.org/obo/GO_0019464 glycine decarboxylation via glycine cleavage system http://purl.obolibrary.org/obo/GO_0006546 glycine catabolic process The chemical reactions and pathways resulting in the breakdown of glycine by oxidative cleavage to carbon dioxide, ammonia, and a methylene group, mediated by enzymes of the glycine cleavage complex. http://purl.obolibrary.org/obo/GO_0019614 catechol-containing compound catabolic process http://purl.obolibrary.org/obo/GO_0019336 phenol-containing compound catabolic process The chemical reactions and pathways resulting in the breakdown of catechol-containing compounds. Catechol is a compound containing a pyrocatechol nucleus or substituent. http://purl.obolibrary.org/obo/CL_0002181 mucous neck cell of gastric gland http://purl.obolibrary.org/obo/CL_0002659 glandular epithelial cell of stomach A columnar epithelial mucous secreting cell located in the neck of the gastric glands. These cells have numerous apical secretory vesicles containing mucins and a basally displaced nucleus. The mucous they secrete is distinct histochemically from that of the surface mucous cells of stomach. http://purl.obolibrary.org/obo/GO_0019626 short-chain fatty acid catabolic process http://purl.obolibrary.org/obo/GO_0046459 short-chain fatty acid metabolic process The chemical reactions and pathways resulting in the breakdown of a short-chain fatty acid. A short-chain fatty acid has an aliphatic tail containing fewer than 6 carbons. http://purl.obolibrary.org/obo/CL_0002183 stem cell of gastric gland http://purl.obolibrary.org/obo/CL_0002178 epithelial cell of stomach A stomach epithelial cell that is olumnar in form with a few short apical microvilli; relatively undifferentiated mitotic cell from which other types of gland are derived; few in number, situated in the isthmus region of the gland and base of the gastric pit. http://purl.obolibrary.org/obo/GO_0019814 immunoglobulin complex http://purl.obolibrary.org/obo/GO_0032991 protein-containing complex A protein complex that in its canonical form is composed of two identical immunoglobulin heavy chains and two identical immunoglobulin light chains, held together by disulfide bonds and sometimes complexed with additional proteins. An immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph. http://purl.obolibrary.org/obo/CL_0002184 basal proper cell of olfactory epithelium http://purl.obolibrary.org/obo/CL_0002169 basal cell of olfactory epithelium A flat or angular epithelial cell with condensed nuclei and darkly staining cytoplasm containing numerous intermediate filaments inserted into desmosomes contacting surrounding supporting cells; lie in contact with the basal lamina of olfactory epithelium. http://purl.obolibrary.org/obo/CL_0002187 basal cell of epidermis http://purl.obolibrary.org/obo/CL_4052061 epidermal keratinocyte A mitotically active, columnar-shaped keratinocyte located in the stratum basale of the epidermis and attached to the basement membrane. This cell exhibits heterogeneity, encompassing stem and progenitor subpopulations with distinct molecular and proliferative characteristics (Haensel et al., 2020), and serves as the primary source of new keratinocytes for epidermal renewal, homeostasis, and regeneration. http://purl.obolibrary.org/obo/GO_0019815 B cell receptor complex http://purl.obolibrary.org/obo/GO_0019814 immunoglobulin complex An immunoglobulin complex that is present in the plasma membrane of B cells and that in its canonical form is composed of two identical immunoglobulin heavy chains and two identical immunoglobulin light chains and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins. http://purl.obolibrary.org/obo/GO_0019825 oxygen binding http://purl.obolibrary.org/obo/GO_0036094 small molecule binding Binding to oxygen (O2). http://purl.obolibrary.org/obo/CL_0002188 glomerular endothelial cell http://purl.obolibrary.org/obo/CL_0002681 kidney cortical cell An endothelial cell that is part of the glomerulus of the kidney. This cell is flattened, highly fenestrated, and plays a vital role in the formation of glomerular ultrafiltrate. http://purl.obolibrary.org/obo/GO_0019896 axonal transport of mitochondrion http://purl.obolibrary.org/obo/GO_0047497 mitochondrion transport along microtubule The directed movement of mitochondria along microtubules in nerve cell axons. http://purl.obolibrary.org/obo/CL_0002189 granular cell of epidermis http://purl.obolibrary.org/obo/CL_4052061 epidermal keratinocyte A keratinocyte located in the stratum granulosum of the epidermis, characterized by the presence of keratohyalin granules containing filaggrin—which aggregate keratin filament —and by lamellar granules that secrete lipids and enzymes essential for forming the skin’s waterproof barrier. As these cells progress toward the surface, they adopt a flattened morphology and initiate keratinization to become corneocyte and form the protective stratum corneum. In human epidermis, granular keratinocytes are transcriptomically distinguished by high expression of differentiation markers such as DSC1, KRT2, IVL, and TGM3 (Wang et al., 2020), and LOR, FLG, and SPINK5 (Cheng et al., 2018). http://purl.obolibrary.org/obo/GO_0021501 prechordal plate formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The formation of the prechordal plate. The prechordal plate is a thickening of the endoderm at the cranial end of the primitive streak formed by the involution of Spemann's organizer cells. The prechordal plate and the notochord induce the formation of the neural plate from the overlying ectodermal cells. http://purl.obolibrary.org/obo/GO_0021508 floor plate formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The formation of a ventral region of glial cells in the neural tube that provides inductive signals for the specification of neuronal cell types. The floor plate is evident at the ventral midline by the neural fold stage. http://purl.obolibrary.org/obo/CL_0002190 squamous cell of epidermis http://purl.obolibrary.org/obo/CL_4052061 epidermal keratinocyte A flat keratinocyte immediately below the cornified layer. http://purl.obolibrary.org/obo/GO_0021509 roof plate formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The formation of a single row of glia at the dorsal midline of the developing neural tube. This region provides inductive signals for the specification of neuronal cell types and of the specification of neural crest cells. The cells comprising the roof plate are the precursors to radial glial cells. http://purl.obolibrary.org/obo/CL_0002191 granulocytopoietic cell http://purl.obolibrary.org/obo/CL_0000839 myeloid lineage restricted progenitor cell A cell involved in the formation of a granulocyte. http://purl.obolibrary.org/obo/GO_0021510 spinal cord development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the spinal cord over time, from its formation to the mature structure. The spinal cord primarily conducts sensory and motor nerve impulses between the brain and the peripheral nervous tissues. http://purl.obolibrary.org/obo/CL_0002192 metamyelocyte http://purl.obolibrary.org/obo/CL_0002191 granulocytopoietic cell A eosinophil precursor in the granulocytic series, being a cell intermediate in development between a myelocyte and a band form cell. The nucleus becomes indented where the indentation is smaller than half the distance to the farthest nuclear margin; chromatin becomes coarse and clumped; specific granules predominate while primary granules are rare. http://purl.obolibrary.org/obo/GO_0021514 ventral spinal cord interneuron differentiation http://purl.obolibrary.org/obo/GO_0021953 central nervous system neuron differentiation The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of ventral spinal cord interneurons. Ventral spinal cord interneurons are cells located in the ventral portion of the spinal cord that transmit signals between sensory and motor neurons and are required for reflexive responses. Differentiation includes the processes involved in commitment of a cell to a specific fate. http://purl.obolibrary.org/obo/CL_0002193 myelocyte http://purl.obolibrary.org/obo/CL_0002191 granulocytopoietic cell A cell type that is the first of the maturation stages of the granulocytic leukocytes normally found in the bone marrow. Granules are seen in the cytoplasm. The nuclear material of the myelocyte is denser than that of the myeloblast but lacks a definable membrane. The cell is flat and contains increasing numbers of granules as maturation progresses. http://purl.obolibrary.org/obo/GO_0021515 cell differentiation in spinal cord http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the spinal cord. Differentiation includes the processes involved in commitment of a cell to a specific fate. http://purl.obolibrary.org/obo/CL_0002194 monopoietic cell http://purl.obolibrary.org/obo/CL_0000839 myeloid lineage restricted progenitor cell A cell involved in the formation of a monocyte (monopoiesis). http://purl.obolibrary.org/obo/CL_0002195 hepatic stem cell http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell A stem cell that can give rise to the cells of the liver. The term usually refers to the self-renewing pool of hepatocyte precursors in the adult liver (differently from 'hepatoblast', often used for fetal precursors of hepatocytes). http://purl.obolibrary.org/obo/GO_0021516 dorsal spinal cord development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the dorsal region of the spinal cord over time, from its formation to the mature structure. The dorsal region of the mature spinal cord contains neurons that process and relay sensory input. http://purl.obolibrary.org/obo/CL_0002196 hepatic oval stem cell http://purl.obolibrary.org/obo/CL_0011026 progenitor cell A transient hepatic stem cell observed after liver injury with a high nuclear to cytoplasm ratio that can differentiate into mature hepatocytes and bile duct cells. Arises from more than one tissue. http://purl.obolibrary.org/obo/GO_0021517 ventral spinal cord development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the ventral region of the spinal cord over time, from its formation to the mature structure. The neurons of the ventral region of the mature spinal cord participate in motor output. http://purl.obolibrary.org/obo/GO_0021522 spinal cord motor neuron differentiation http://purl.obolibrary.org/obo/GO_0021953 central nervous system neuron differentiation The process in which neuroepithelial cells in the ventral neural tube acquire specialized structural and/or functional features of motor neurons. Motor neurons innervate an effector (muscle or glandular) tissue and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate. http://purl.obolibrary.org/obo/CL_0002197 inactive chief cell of parathyoid gland http://purl.obolibrary.org/obo/CL_0000446 chief cell of parathyroid gland A parathyroid chief cell that is not actively secreting hormone. Contains small Golgi complexes with only a few grouped vesicles and membrane-bound secretory granules; glycogen and many lipofuscin granules abound but sacs of granular endoplasmic reticulum are rare and dispersed. In normal humans, inactive chief cells out number active chief cells in a ratio of 3-5:1. http://purl.obolibrary.org/obo/CL_0002198 oncocyte http://purl.obolibrary.org/obo/CL_0002076 endo-epithelial cell A large epithelial cell with an extremely acidophilic and granular cytoplasm, containing vast numbers of mitochondria; such cells may undergo neoplastic transformation. From the Greek word onkos meaning swelling, this cell type is found in parathyroid, salivary and thyroid glands. http://purl.obolibrary.org/obo/GO_0021523 somatic motor neuron differentiation http://purl.obolibrary.org/obo/GO_0021522 spinal cord motor neuron differentiation The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of somatic motor neurons. Somatic motor neurons innervate skeletal muscle targets and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate. http://purl.obolibrary.org/obo/CL_0002199 oxyphil cell of parathyroid gland http://purl.obolibrary.org/obo/CL_0002260 epithelial cell of parathyroid gland An oncocyte located in the parathyroid gland. http://purl.obolibrary.org/obo/GO_0021525 lateral motor column neuron differentiation http://purl.obolibrary.org/obo/GO_0021522 spinal cord motor neuron differentiation The process in which differentiating motor neurons in the neural tube acquire the specialized structural and/or functional features of lateral motor column neurons. Lateral motor column neurons are generated only on limb levels and send axons into the limb mesenchyme. Differentiation includes the processes involved in commitment of a cell to a specific fate. http://purl.obolibrary.org/obo/CL_0002200 oxyphil cell of thyroid http://purl.obolibrary.org/obo/CL_0002257 epithelial cell of thyroid gland An oncocyte located in the thyroid. http://purl.obolibrary.org/obo/CL_0002201 renal beta-intercalated cell http://purl.obolibrary.org/obo/CL_0005010 renal intercalated cell A renal intercalated cell that secretes base and reabsorbs acid in the distal segments of the kidney tubule to maintain acid/base balance. http://purl.obolibrary.org/obo/GO_0021531 spinal cord radial glial cell differentiation http://purl.obolibrary.org/obo/GO_0060019 radial glial cell differentiation The process in which neuroepithelial cells in the ventral neural tube acquire specialized structural and/or functional features of radial glial cells. Radial cell precursors differentiate into both neuronal cell types and mature radial glial cells. Mature radial glial cells regulate the axon growth and pathfinding processes that occur during white matter patterning of the developing spinal cord. Differentiation includes the processes involved in commitment of a cell to a specific fate. http://purl.obolibrary.org/obo/CL_0002202 epithelial cell of tracheobronchial tree http://purl.obolibrary.org/obo/CL_0002632 epithelial cell of lower respiratory tract An epithelial cell of the tracheobronchial tree. http://purl.obolibrary.org/obo/CL_0002203 tuft cell of large intestine http://purl.obolibrary.org/obo/CL_0002253 epithelial cell of large intestine A tuft cell that is part of the epithelium of large intestine. http://purl.obolibrary.org/obo/GO_0021532 neural tube patterning http://purl.obolibrary.org/obo/GO_0003002 regionalization The regionalization process that regulates the coordinated growth that establishes the non-random spatial arrangement of the neural tube. http://purl.obolibrary.org/obo/CL_0002204 tuft cell http://purl.obolibrary.org/obo/CL_0000066 epithelial cell An epithelial cell found in various organs, including the gastrointestinal and respiratory tracts, characterized by a tuft of 120-140 blunt microvilli on its apical surface. This cell exhibits diverse functions depending on its location, which includes chemosensation, initiation of immune responses, contribution to mucociliary clearance, and defense against parasites. http://purl.obolibrary.org/obo/GO_0021533 cell differentiation in hindbrain http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mature cells of the hindbrain. Differentiation includes the processes involved in commitment of a cell to a specific fate. http://purl.obolibrary.org/obo/CL_0002205 brush cell of lobular bronchiole http://purl.obolibrary.org/obo/CL_0002075 brush cell of tracheobronchial tree A brush cell found in the epithelium of lobular bronchiole. http://purl.obolibrary.org/obo/GO_0021534 cell proliferation in hindbrain http://purl.obolibrary.org/obo/GO_0061351 neural precursor cell proliferation The multiplication or reproduction of cells, resulting in the expansion of a cell population in the hindbrain. http://purl.obolibrary.org/obo/CL_0002206 brush cell of terminal bronchiole http://purl.obolibrary.org/obo/CL_0002075 brush cell of tracheobronchial tree A brush cell of the epithelium in the terminal bronchiole. http://purl.obolibrary.org/obo/GO_0021535 cell migration in hindbrain http://purl.obolibrary.org/obo/GO_0016477 cell migration The orderly movement of a cell that will reside in the hindbrain. http://purl.obolibrary.org/obo/CL_0002207 brush cell of trachea http://purl.obolibrary.org/obo/CL_0002075 brush cell of tracheobronchial tree Brush cell of the epithelium in the trachea. http://purl.obolibrary.org/obo/GO_0021536 diencephalon development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the diencephalon over time, from its formation to the mature structure. The diencephalon is the paired caudal parts of the prosencephalon from which the thalamus, hypothalamus, epithalamus and subthalamus are derived; these regions regulate autonomic, visceral and endocrine function, and process information directed to the cerebral cortex. http://purl.obolibrary.org/obo/CL_0002208 brush cell of bronchus http://purl.obolibrary.org/obo/CL_0002328 bronchial epithelial cell A brush cell found in the epithelium of bronchus. http://purl.obolibrary.org/obo/GO_0021537 telencephalon development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the telencephalon over time, from its formation to the mature structure. The telencephalon is the paired anteriolateral division of the prosencephalon plus the lamina terminalis from which the olfactory lobes, cerebral cortex, and subcortical nuclei are derived. http://purl.obolibrary.org/obo/CL_0002209 intermediate epitheliocyte http://purl.obolibrary.org/obo/CL_0002202 epithelial cell of tracheobronchial tree An epithelial cell present in the trachea and bronchi; columnar in shape; generally lack cilia; immature forms of ciliated or secretory cells which have been formed from stem cells. http://purl.obolibrary.org/obo/CL_0002210 red muscle cell http://purl.obolibrary.org/obo/CL_0008046 extrafusal muscle fiber A slow muscle cell that contains high levels of myoglobin and oxygen storing proteins giving the cell a red appearance. http://purl.obolibrary.org/obo/GO_0021538 epithalamus development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the epithalamus over time from its initial formation until its mature state. The epithalamus is the small dorsomedial area of the thalamus including the habenular nuclei and associated fiber bundles, the pineal body, and the epithelial roof of the third ventricle. http://purl.obolibrary.org/obo/CL_0002211 type I muscle cell http://purl.obolibrary.org/obo/CL_0002210 red muscle cell A slow muscle cell that has large amounts of myoglobin, stores energy as triglycerides, generates ATP by the oxidative method and is resistant to fatigue. http://purl.obolibrary.org/obo/GO_0021539 subthalamus development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the subthalamus over time, from its formation to the mature structure. The subthalamus is the anterior part of the diencephalon that lies between the thalamus, hypothalamus, and tegmentum of the mesencephalon, including subthalamic nucleus, zona incerta, the fields of Forel, and the nucleus of ansa lenticularis. http://purl.obolibrary.org/obo/CL_0002212 type II muscle cell http://purl.obolibrary.org/obo/CL_0000190 fast muscle cell A fast muscle fiber cell that stores energy in the form of glycogen and creatine phosphate. http://purl.obolibrary.org/obo/GO_0021540 corpus callosum morphogenesis http://purl.obolibrary.org/obo/GO_0021952 central nervous system projection neuron axonogenesis The process in which the anatomical structures of the corpus callosum are generated and organized. The corpus callosum is a thick bundle of nerve fibers comprising a commissural plate connecting the two cerebral hemispheres. It consists of contralateral axon projections that provides communications between the right and left cerebral hemispheres. http://purl.obolibrary.org/obo/CL_0002213 white muscle cell http://purl.obolibrary.org/obo/CL_0000190 fast muscle cell A muscle cell with low content of myoglobin and other oxygen storing proteins. This muscle cell has a white appearance. http://purl.obolibrary.org/obo/CL_0002214 type IIa muscle cell http://purl.obolibrary.org/obo/CL_0002212 type II muscle cell A type II muscle cell that contains large amounts of myoglobin, has many mitochondria and very many blood capillaries. Type II A cells are red, have a very high capacity for generating ATP by oxidative metabolic processes, split ATP at a very rapid rate, have a fast contraction velocity and are resistant to fatigue. http://purl.obolibrary.org/obo/GO_0021541 ammon gyrus development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the ammon gyrus over time, from its formation to the mature structure. The ammon gyrus, often subdivided into the CA1 and CA3 regions, is one of the two interlocking gyri of the hippocampus that is rich in large pyramidal neurons. http://purl.obolibrary.org/obo/CL_0002215 type IIb muscle cell http://purl.obolibrary.org/obo/CL_0002213 white muscle cell A type II muscle cell that contains a low content of myoglobin, relatively few mitochondria, relatively few blood capillaries and large amounts of glycogen. Type II B fibres are white, geared to generate ATP by anaerobic metabolic processes, not able to supply skeletal muscle fibres continuously with sufficient ATP, fatigue easily, split ATP at a fast rate and have a fast contraction velocity. http://purl.obolibrary.org/obo/GO_0021542 dentate gyrus development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the dentate gyrus over time, from its formation to the mature structure. The dentate gyrus is one of two interlocking gyri of the hippocampus. It contains granule cells, which project to the pyramidal cells and interneurons of the CA3 region of the ammon gyrus. http://purl.obolibrary.org/obo/CL_0002216 intermediate muscle cell http://purl.obolibrary.org/obo/CL_0008046 extrafusal muscle fiber An intermediate muscle cell that has characteristics of both fast and slow muscle cells. http://purl.obolibrary.org/obo/GO_0021543 pallium development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the pallium over time, from its formation to the mature structure. The pallium is the roof region of the telencephalon. http://purl.obolibrary.org/obo/CL_0002217 intermediate trophoblast cell http://purl.obolibrary.org/obo/CL_0000351 trophoblast cell A trophoblast that leaves the placenta and invades the endometrium and myometrium. This cell type is crucial in increasing blood flow to the fetus. http://purl.obolibrary.org/obo/GO_0021544 subpallium development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the subpallium over time, from its formation to the mature structure. The subpallium is the base region of the telencephalon. http://purl.obolibrary.org/obo/CL_0002218 immature dendritic epithelial T cell precursor http://purl.obolibrary.org/obo/CL_0002404 fetal thymocyte A double negative thymocyte that has a T cell receptor consisting of a gamma chain that has as part a Vgamma3 segment, and a delta chain. This cell type is CD4-negative, CD8-negative and CD24-positive. This cell-type is found in the fetal thymus with highest numbers occurring at E17-E18. http://purl.obolibrary.org/obo/GO_0021545 cranial nerve development http://purl.obolibrary.org/obo/GO_0021675 nerve development The process whose specific outcome is the progression of the cranial nerves over time, from its formation to the mature structure. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions. http://purl.obolibrary.org/obo/CL_0002219 anchoring trophoblast http://purl.obolibrary.org/obo/CL_0000351 trophoblast cell A trophoblast found at the junction of the placenta. This cell type makes a unique fibronectin-trophouteronectin junction that helps mediate attachment of the placenta to the uterus. This cell type is also found junction of the chorion layer of the external membranes and the decidua. http://purl.obolibrary.org/obo/CL_0002220 interstitial cell of pineal gland http://purl.obolibrary.org/obo/CL_0000710 neurecto-epithelial cell A cell located between the pinealocytes. http://purl.obolibrary.org/obo/GO_0021546 rhombomere development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the rhombomere over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. http://purl.obolibrary.org/obo/CL_0002221 keratinized squamous cell of esophagus http://purl.obolibrary.org/obo/CL_0002252 epithelial cell of esophagus A squamous cell that has keratin in the esophagus. http://purl.obolibrary.org/obo/GO_0021547 midbrain-hindbrain boundary initiation http://purl.obolibrary.org/obo/GO_0003002 regionalization The regionalization process that gives rise to the midbrain-hindbrain boundary. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate. http://purl.obolibrary.org/obo/CL_0002222 vertebrate lens cell http://purl.obolibrary.org/obo/CL_0000306 crystallin accumulating cell A cell comprising the transparent, biconvex body separating the posterior chamber and vitreous body, and constituting part of the refracting mechanism of the mammalian eye. http://purl.obolibrary.org/obo/CL_0002223 anterior lens cell http://purl.obolibrary.org/obo/CL_0020029 cuboidal epithelial cell A cell of the transparent layer of simple cuboidal epithelium over the anterior surface of the lens; transform into lens fiber(s). http://purl.obolibrary.org/obo/GO_0021548 pons development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the pons over time, from its formation to the mature structure. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum. http://purl.obolibrary.org/obo/GO_0021549 cerebellum development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the cerebellum over time, from its formation to the mature structure. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. In mice, the cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills. http://purl.obolibrary.org/obo/CL_0002224 lens epithelial cell http://purl.obolibrary.org/obo/CL_0002222 vertebrate lens cell A cell of the cuboidal epithelium that covers the lens. The cells of the lens epithelium regulate most of the homeostatic functions of the lens. As ions, nutrients, and liquid enter the lens from the aqueous humor, Na+/K+ ATPase pumps in the lens epithelial cells pump ions out of the lens to maintain appropriate lens osmolarity and volume, with equatorially positioned lens epithelium cells contributing most to this current. The activity of the Na+/K+ ATPases keeps water and current flowing through the lens from the poles and exiting through the equatorial regions. The cells of the lens epithelium also serve as the progenitors for new lens fibers. It constantly lays down fibers in the embryo, fetus, infant, and adult, and continues to lay down fibers for lifelong growth. http://purl.obolibrary.org/obo/GO_0021550 medulla oblongata development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the medulla oblongata over time, from its formation to the mature structure. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate. http://purl.obolibrary.org/obo/GO_0021551 central nervous system morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structure of the central nervous system is generated and organized. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord. http://purl.obolibrary.org/obo/CL_0002225 secondary lens fiber http://purl.obolibrary.org/obo/CL_0011004 lens fiber cell A lens fiber cell that develops from primary lens fiber; located towards the center of lens; cell organelles are normally degraded or in the process of being degraded. http://purl.obolibrary.org/obo/CL_0002226 non-nucleated secondary lens fiber http://purl.obolibrary.org/obo/CL_0002225 secondary lens fiber A secondary lens fiber cell that lacks a nucleus. http://purl.obolibrary.org/obo/GO_0021553 olfactory nerve development http://purl.obolibrary.org/obo/GO_0021545 cranial nerve development The process whose specific outcome is the progression of the olfactory nerve over time, from its formation to the mature structure. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem. http://purl.obolibrary.org/obo/CL_0002227 nucleated secondary lens fiber http://purl.obolibrary.org/obo/CL_0002225 secondary lens fiber A secondary fiber cell that contains a nucleus. http://purl.obolibrary.org/obo/CL_0002228 primary lens fiber http://purl.obolibrary.org/obo/CL_0011004 lens fiber cell An elongating cell that rapidly obliterates the lumen of the lens vesicle. Subsequently, differentiation of this cell type at the lens equator leads to the formation of secondary fiber cells that come to overlie the primary fibers. http://purl.obolibrary.org/obo/GO_0021554 optic nerve development http://purl.obolibrary.org/obo/GO_0021545 cranial nerve development The process whose specific outcome is the progression of the optic nerve over time, from its formation to the mature structure. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain. http://purl.obolibrary.org/obo/CL_0002229 light chief cell of parathyroid gland http://purl.obolibrary.org/obo/CL_0000446 chief cell of parathyroid gland A chief cell that is bigger than dark chief cells and has a larger and lighter nucleus and a cytoplasm with few granules. http://purl.obolibrary.org/obo/CL_0002231 epithelial cell of prostate http://purl.obolibrary.org/obo/CL_0002076 endo-epithelial cell An epithelial cell of the prostate. http://purl.obolibrary.org/obo/GO_0021555 midbrain-hindbrain boundary morphogenesis http://purl.obolibrary.org/obo/GO_0048598 embryonic morphogenesis The process in which the anatomical structure of the midbrain-hindbrain boundary is generated and organized. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate. http://purl.obolibrary.org/obo/CL_0002232 epithelial cell of prostatic duct http://purl.obolibrary.org/obo/CL_0002231 epithelial cell of prostate An epithelial cell of prostatic duct. http://purl.obolibrary.org/obo/CL_0002233 epithelial cell of prostatic acinus http://purl.obolibrary.org/obo/CL_0002231 epithelial cell of prostate An epithelial cell of the prostatic acinus. http://purl.obolibrary.org/obo/GO_0021556 central nervous system formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process that gives rise to the central nervous system. This process pertains to the initial formation of a structure from unspecified parts. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain, spinal cord and spinal nerves. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord. http://purl.obolibrary.org/obo/CL_0002234 basal cell of prostatic acinus http://purl.obolibrary.org/obo/CL_0002341 basal cell of prostate epithelium A cell of the basal layer of the epithelium in the prostatic acinus. http://purl.obolibrary.org/obo/CL_0002235 luminal cell of prostatic acinus http://purl.obolibrary.org/obo/CL_0002340 luminal cell of prostate epithelium A cell of the luminal layer of the epithelium in the prostatic acinus. http://purl.obolibrary.org/obo/GO_0021557 oculomotor nerve development http://purl.obolibrary.org/obo/GO_0021545 cranial nerve development The process whose specific outcome is the progression of the oculomotor nerve over time, from its formation to the mature structure. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle. http://purl.obolibrary.org/obo/CL_0002236 basal epithelial cell of prostatic duct http://purl.obolibrary.org/obo/CL_0002341 basal cell of prostate epithelium A cell that constitutes the basal layer of epithelium in the prostatic duct. http://purl.obolibrary.org/obo/CL_0002237 luminal epithelial cell of prostatic duct http://purl.obolibrary.org/obo/CL_0002340 luminal cell of prostate epithelium A cell that constitutes the luminal layer of epithelium of prostatic duct. http://purl.obolibrary.org/obo/GO_0021559 trigeminal nerve development http://purl.obolibrary.org/obo/GO_0021545 cranial nerve development The process whose specific outcome is the progression of the trigeminal nerve over time, from its formation to the mature structure. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae. http://purl.obolibrary.org/obo/CL_0002238 male gonocyte http://purl.obolibrary.org/obo/CL_0000670 primordial germ cell A primordial germ cell that is destined to become a male germ cell. http://purl.obolibrary.org/obo/GO_0021561 facial nerve development http://purl.obolibrary.org/obo/GO_0021545 cranial nerve development The process whose specific outcome is the progression of the facial nerve over time, from its formation to the mature structure. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial ophthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives off nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities. http://purl.obolibrary.org/obo/CL_0002239 ooblast http://purl.obolibrary.org/obo/CL_0000670 primordial germ cell A primordial cell from which an oocyte (ovum) ultimately is developed. http://purl.obolibrary.org/obo/CL_0002240 marrow fibroblast http://purl.obolibrary.org/obo/CL_0010001 stromal cell of bone marrow A fibroblast in the bone marrow. http://purl.obolibrary.org/obo/GO_0021562 vestibulocochlear nerve development http://purl.obolibrary.org/obo/GO_0021545 cranial nerve development The process whose specific outcome is the progression of the vestibulocochlear nerve over time, from its formation to the mature structure. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea. http://purl.obolibrary.org/obo/CL_0002241 pulmonary interstitial fibroblast http://purl.obolibrary.org/obo/CL_0000057 fibroblast A fibroblasts found in interstitial spaces in the pulmonary tract. Greater numbers of these cells are found in idiopathic pulmonary fibrosis. http://purl.obolibrary.org/obo/CL_0002242 nucleate cell http://purl.obolibrary.org/obo/CL_0000000 cell A cell containing at least one nucleus. http://purl.obolibrary.org/obo/GO_0021563 glossopharyngeal nerve development http://purl.obolibrary.org/obo/GO_0021545 cranial nerve development Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion. http://purl.obolibrary.org/obo/CL_0002243 smooth muscle cell of sphincter of pupil http://purl.obolibrary.org/obo/CL_0000358 sphincter associated smooth muscle cell A circular smooth muscle cell of the iris, innervated by the ciliary nerves (parasympathetic), and acting to contract the pupil. This muscle cell derives from neuroectoderm. This smooth muscle cell results from transformation of epithelial cells to smooth muscle cells. http://purl.obolibrary.org/obo/GO_0021564 vagus nerve development http://purl.obolibrary.org/obo/GO_0021545 cranial nerve development The process whose specific outcome is the progression of the vagus nerve over time, from its formation to the mature structure. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis. http://purl.obolibrary.org/obo/CL_0002244 squamous cell of ectocervix http://purl.obolibrary.org/obo/CL_1001575 uterine cervix squamous cell A stratified squamous epithelial cell located in the ectocervix. http://purl.obolibrary.org/obo/CL_0002246 peripheral blood stem cell http://purl.obolibrary.org/obo/CL_0000080 circulating cell A hematopoeitic stem cell found in the blood. Normally found in very limited numbers in the peripheral circulation (less than 0.1% of all nucleated cells). http://purl.obolibrary.org/obo/GO_0021565 accessory nerve development http://purl.obolibrary.org/obo/GO_0021545 cranial nerve development The process whose specific outcome is the progression of the accessory nerve over time, from its formation to the mature structure. In mice, the spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve. http://purl.obolibrary.org/obo/CL_0002247 pleural macrophage http://purl.obolibrary.org/obo/CL_0000864 tissue-resident macrophage A tissue macrophage that is in the pleural space. http://purl.obolibrary.org/obo/CL_0002248 pluripotent stem cell http://purl.obolibrary.org/obo/CL_0000723 somatic stem cell A pluripotent stem cell has the ability to form cells from all three germ layers (ectoderm, mesoderm, and endoderm). However, unlike totipotent stem cells, they cell can not generate all the cells of the whole organism such as placenta. http://purl.obolibrary.org/obo/GO_0021566 hypoglossal nerve development http://purl.obolibrary.org/obo/GO_0021545 cranial nerve development The process whose specific outcome is the progression of the hypoglossal nerve over time, from its formation to the mature structure. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue. http://purl.obolibrary.org/obo/CL_0002249 primitive cardiac myocyte http://purl.obolibrary.org/obo/CL_0002078 meso-epithelial cell A stem cell that can differentiate into a cardiac myocyte. http://purl.obolibrary.org/obo/GO_0021567 rhombomere 1 development http://purl.obolibrary.org/obo/GO_0021546 rhombomere development The process whose specific outcome is the progression of rhombomere 1 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order. http://purl.obolibrary.org/obo/CL_0002250 intestinal crypt stem cell http://purl.obolibrary.org/obo/CL_0002563 intestinal epithelial cell A stem cell located in epithelium the based of the crypt of Lieberkuhn. Division of these cells serve both to maintain the stem cell population and produce the transit amplifying cells that are all precursors of all cell types that populate the intestinal epithelium. http://purl.obolibrary.org/obo/CL_0002251 epithelial cell of alimentary canal http://purl.obolibrary.org/obo/CL_0002076 endo-epithelial cell An epithelial cell of the musculomembranous digestive tube extending from the mouth to the anus. http://purl.obolibrary.org/obo/GO_0021575 hindbrain morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structure of the hindbrain is generated and organized. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions. http://purl.obolibrary.org/obo/CL_0002252 epithelial cell of esophagus http://purl.obolibrary.org/obo/CL_0002251 epithelial cell of alimentary canal An epithelial cell of the lining of the esophagus. http://purl.obolibrary.org/obo/GO_0021576 hindbrain formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process that gives rise to the hindbrain. This process pertains to the initial formation of a structure from unspecified parts. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions. http://purl.obolibrary.org/obo/CL_0002253 epithelial cell of large intestine http://purl.obolibrary.org/obo/CL_0002563 intestinal epithelial cell An epithelial cell of the lining of the large intestine. http://purl.obolibrary.org/obo/CL_0002254 epithelial cell of small intestine http://purl.obolibrary.org/obo/CL_0002563 intestinal epithelial cell An epithelial cell of the lining of the small intestine. http://purl.obolibrary.org/obo/GO_0021578 hindbrain maturation http://purl.obolibrary.org/obo/GO_0071695 anatomical structure maturation A developmental process, independent of morphogenetic (shape) change, that is required for the hindbrain to attain its fully functional state. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions. http://purl.obolibrary.org/obo/CL_0002255 stromal cell of endometrium http://purl.obolibrary.org/obo/CL_0000499 stromal cell A stromal cell of the endometrium, characterized by its fibroblast-like morphology, regenerative capacity, and ability to undergo decidualization. It differentiates into a decidual stromal cell during pregnancy, essential for embryo implantation and maintenance. This cell is involved in tissue proliferation, remodeling, and breakdown, responding to hormonal changes, particularly estrogen and progesterone. http://purl.obolibrary.org/obo/CL_0002256 supporting cell of carotid body http://purl.obolibrary.org/obo/CL_0000710 neurecto-epithelial cell A supportive cell that has characteristics of glial cell. Processes of this cell envelope the junctions between glomus cells and nerve endings. http://purl.obolibrary.org/obo/GO_0021579 medulla oblongata morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structure of the medulla oblongata is generated and organized. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate. http://purl.obolibrary.org/obo/CL_0002257 epithelial cell of thyroid gland http://purl.obolibrary.org/obo/CL_0002076 endo-epithelial cell An epithelial cell of thyroid gland. http://purl.obolibrary.org/obo/CL_0002258 thyroid follicular cell http://purl.obolibrary.org/obo/CL_0002257 epithelial cell of thyroid gland An epithelial cell that is part of the thyroid follicle epithelium, with a shape that ranges from squamous when inactive to cuboidal or columnar when active, reflecting its hormonal activity. Its apical surface is lined with microvilli projecting into the colloid-filled lumen, where it synthesizes, stores, and secretes the thyroid hormones thyroxine (T4) and triiodothyronine (T3), releasing them into the bloodstream in response to thyroid-stimulating hormone (TSH). http://purl.obolibrary.org/obo/GO_0021580 medulla oblongata formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process that gives rise to the medulla oblongata. This process pertains to the initial formation of a structure from unspecified parts. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate. http://purl.obolibrary.org/obo/CL_0002259 neuroepithelial stem cell http://purl.obolibrary.org/obo/CL_0000723 somatic stem cell The stem cell from which glial precursor cell arises from. http://purl.obolibrary.org/obo/CL_0002260 epithelial cell of parathyroid gland http://purl.obolibrary.org/obo/CL_0002076 endo-epithelial cell An epithelial cell of the parathyroid gland. http://purl.obolibrary.org/obo/GO_0021582 medulla oblongata maturation http://purl.obolibrary.org/obo/GO_0071695 anatomical structure maturation A developmental process, independent of morphogenetic (shape) change, that is required for the medulla oblongata to attain its fully functional state. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate. http://purl.obolibrary.org/obo/CL_0002261 endothelial cell of viscerocranial mucosa http://purl.obolibrary.org/obo/CL_0002076 endo-epithelial cell An endothelial cell found in the mucosa associated with the facial skeleton. http://purl.obolibrary.org/obo/CL_0002262 endothelial cell of sinusoid http://purl.obolibrary.org/obo/CL_0000071 blood vessel endothelial cell An endothelial cell that lines any of the venous cavities through which blood passes in various glands and organs such as the spleen and liver. http://purl.obolibrary.org/obo/GO_0021583 pons morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structure of the pons is generated and organized. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum. http://purl.obolibrary.org/obo/CL_0002263 transitional cell of parathyroid gland http://purl.obolibrary.org/obo/CL_0002260 epithelial cell of parathyroid gland One of three types of epithelial cells that populate the parathyroid gland; cytological characteristics intermediate between those of the chief cell and of the oxyphil cell. Because only one hormone is produced, the three cell forms are widely believed to be different phases in the life cycle of a single cell type, with the chief cell being its physiologically active stage. http://purl.obolibrary.org/obo/CL_0002264 type A cell of stomach http://purl.obolibrary.org/obo/CL_1001517 stomach enteroendocrine cell A type of enteroendocrine cell found in the stomach that secretes glucagon. http://purl.obolibrary.org/obo/GO_0021584 pons formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process that gives rise to the pons. This process pertains to the initial formation of a structure from unspecified parts. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum. http://purl.obolibrary.org/obo/CL_0002265 type D cell of colon http://purl.obolibrary.org/obo/CL_0009042 enteroendocrine cell of colon A D cell located in the colon. http://purl.obolibrary.org/obo/CL_0002266 type D cell of small intestine http://purl.obolibrary.org/obo/CL_0009006 enteroendocrine cell of small intestine A type D cell of the small intestine. http://purl.obolibrary.org/obo/GO_0021586 pons maturation http://purl.obolibrary.org/obo/GO_0071695 anatomical structure maturation A developmental process, independent of morphogenetic (shape) change, that is required for the pons to attain its fully functional state. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum. http://purl.obolibrary.org/obo/CL_0002267 type D cell of stomach http://purl.obolibrary.org/obo/CL_1000222 stomach neuroendocrine cell A type D cell found in the stomach. http://purl.obolibrary.org/obo/GO_0021587 cerebellum morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structure of the cerebellum is generated and organized. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. The cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills. http://purl.obolibrary.org/obo/CL_0002268 P/D1 enteroendocrine cell http://purl.obolibrary.org/obo/CL_0002269 vasoactive intestinal peptide secreting cell An enteroendocrine cell that stores and secretes Ghrelin. http://purl.obolibrary.org/obo/GO_0021588 cerebellum formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process that gives rise to the cerebellum. This process pertains to the initial formation of a structure from unspecified parts. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. The cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills. http://purl.obolibrary.org/obo/CL_0002269 vasoactive intestinal peptide secreting cell http://purl.obolibrary.org/obo/CL_0000167 peptide hormone secreting cell An endocrine cell that secretes vasoactive intestinal peptide. http://purl.obolibrary.org/obo/GO_0021590 cerebellum maturation http://purl.obolibrary.org/obo/GO_0071695 anatomical structure maturation A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellum to attain its fully functional state. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. The cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills. http://purl.obolibrary.org/obo/CL_0002270 type EC2 enteroendocrine cell http://purl.obolibrary.org/obo/CL_1001516 intestinal enteroendocrine cell A type EC enteroendocrine cell in the duodenum and jejunum that stores and secretes motilin and 5-hydroxytryptamine. http://purl.obolibrary.org/obo/GO_0021591 ventricular system development http://purl.obolibrary.org/obo/GO_0048731 system development The process whose specific outcome is the progression of the brain ventricular system over time, from its formation to the mature structure. The brain ventricular system consists of four communicating cavities within the brain that are continuous with the central canal of the spinal cord. These cavities include two lateral ventricles, the third ventricle and the fourth ventricle. Cerebrospinal fluid fills the ventricles and is produced by the choroid plexus. http://purl.obolibrary.org/obo/CL_0002271 type EC1 enteroendocrine cell http://purl.obolibrary.org/obo/CL_1001516 intestinal enteroendocrine cell A type EC enteredocrine cell in the intestines that stores and secretes substance P and 5-hydroxytryptamine. http://purl.obolibrary.org/obo/GO_0021592 fourth ventricle development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the fourth ventricle over time, from its formation to the mature structure. The fourth ventricle is an irregularly shaped cavity in the rhombencephalon, between the medulla oblongata, the pons, and the isthmus in front, and the cerebellum behind. It is continuous with the central canal of the cord below and with the cerebral aqueduct above, and through its lateral and median apertures it communicates with the subarachnoid space. http://purl.obolibrary.org/obo/CL_0002272 motilin secreting cell http://purl.obolibrary.org/obo/CL_0000167 peptide hormone secreting cell A cell that secretes motilin, a gastric hormone that at low pH inhibits gastric motor activity, whereas at high pH has a stimulating effect. http://purl.obolibrary.org/obo/CL_0002273 type ECL enteroendocrine cell http://purl.obolibrary.org/obo/CL_0002274 histamine secreting cell A type EC enteroendocrine cell type that is numerous in the fundus of the stomach; stores 5-hydroxytryptamine and histamine. http://purl.obolibrary.org/obo/GO_0021593 rhombomere morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structure of the rhombomere is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. http://purl.obolibrary.org/obo/CL_0002274 histamine secreting cell http://purl.obolibrary.org/obo/CL_0000457 biogenic amine secreting cell A cell type that secretes histamine. http://purl.obolibrary.org/obo/CL_0002275 pancreatic PP cell http://purl.obolibrary.org/obo/CL_0008024 pancreatic endocrine cell A PP cell located in the islets of the pancreas. http://purl.obolibrary.org/obo/GO_0021594 rhombomere formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process that gives rise to the rhombomere. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. http://purl.obolibrary.org/obo/CL_0002277 type I enteroendocrine cell http://purl.obolibrary.org/obo/CL_0009006 enteroendocrine cell of small intestine An enteroendocrine cell commonest in the duodenum and jejunum, rare in ileum, that secretes cholecystokinin. This cell type is involved in the regulation of digestive enzymes and bile. http://purl.obolibrary.org/obo/CL_0002278 GIP cell http://purl.obolibrary.org/obo/CL_0009006 enteroendocrine cell of small intestine An enteroendocrine cell of duodenum and jejunum that produces gastric inhibitory peptide. http://purl.obolibrary.org/obo/GO_0021602 cranial nerve morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structure of the cranial nerves are generated and organized. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions. http://purl.obolibrary.org/obo/CL_0002279 type L enteroendocrine cell http://purl.obolibrary.org/obo/CL_1001516 intestinal enteroendocrine cell A enteroendocrine cell type that is numerous in ileum, present in jejunum and large intestine, few in duodenum. This cell type produces glucagon-like immunoreactants (glicentin, glucagon-37, glucagon-29, GLP-1 and -2) and PYY. http://purl.obolibrary.org/obo/CL_0002280 type N enteroendocrine cell http://purl.obolibrary.org/obo/CL_0009006 enteroendocrine cell of small intestine An enteroendocrine cell found in the ileum and jejunum that produces neurotensin. http://purl.obolibrary.org/obo/GO_0021603 cranial nerve formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process that gives rise to the cranial nerves. This process pertains to the initial formation of a structure from unspecified parts. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions. http://purl.obolibrary.org/obo/CL_0002281 type S enteroendocrine cell http://purl.obolibrary.org/obo/CL_0009006 enteroendocrine cell of small intestine Scattered in duodenojejunal mucosa, this enteroendocrine cell secretes secretin and serotonin. http://purl.obolibrary.org/obo/CL_0002282 type TG enteroendocrine cell http://purl.obolibrary.org/obo/CL_0000509 gastrin secreting cell An enteroendocrine cell which produces a gastrin- and cholecystokinin-like peptide. The apical microvilli-rich plasma membrane is in open contact with the small intestine mucosa. This cell type is devoid of gastrin-17 but contains other fragments of the gastrin polypeptide. http://purl.obolibrary.org/obo/GO_0021605 cranial nerve maturation http://purl.obolibrary.org/obo/GO_0021682 nerve maturation A developmental process, independent of morphogenetic (shape) change, that is required for a cranial nerve to attain its fully functional state. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions. http://purl.obolibrary.org/obo/CL_0002283 ecto-epithelial cell of viscerocranial mucosa http://purl.obolibrary.org/obo/CL_0002159 general ecto-epithelial cell An epithelial cell of the mucosa associated with facial skeleton. http://purl.obolibrary.org/obo/CL_0002284 type X enteroendocrine cell http://purl.obolibrary.org/obo/CL_0005018 ghrelin secreting cell An enteroendocrine cell found in the fundus and pylorus; this cell type has dense round secretory granules that contain ghrelin. http://purl.obolibrary.org/obo/GO_0021606 accessory nerve maturation http://purl.obolibrary.org/obo/GO_0021605 cranial nerve maturation A developmental process, independent of morphogenetic (shape) change, that is required for the accessory nerve to attain its fully functional state. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve. http://purl.obolibrary.org/obo/CL_0002285 type III taste bud cell http://purl.obolibrary.org/obo/CL_0000209 taste receptor cell A taste receptor cell that is characterized by morphologically identifiable synaptic contacts with the gustatory nerve fibers and expression of the synaptic membrane protein-25 (SNAP-25) and NCAM. http://purl.obolibrary.org/obo/CL_0002286 type II taste cell http://purl.obolibrary.org/obo/CL_0000209 taste receptor cell A taste receptor cell that has a short microvilli, a projecting apical region, a large rounded nucleus, and expresses taste chemoreceptors thus making them the transducing cell for taste qualities. http://purl.obolibrary.org/obo/GO_0021607 accessory nerve morphogenesis http://purl.obolibrary.org/obo/GO_0021602 cranial nerve morphogenesis The process in which the anatomical structure of the accessory nerve is generated and organized. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve. http://purl.obolibrary.org/obo/CL_0002287 type IV taste receptor cell http://purl.obolibrary.org/obo/CL_0000209 taste receptor cell A rounded, mitotically active stem cell which is the source of new cells of the taste bud; located basally. http://purl.obolibrary.org/obo/CL_0002288 type V taste receptor cell http://purl.obolibrary.org/obo/CL_0000209 taste receptor cell A cell type that forms the boundary with the surrounding epithelium. http://purl.obolibrary.org/obo/GO_0021608 accessory nerve formation http://purl.obolibrary.org/obo/GO_0021603 cranial nerve formation The process that gives rise to the accessory nerve. This process pertains to the initial formation of a structure from unspecified parts. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve. http://purl.obolibrary.org/obo/CL_0002289 type I taste bud cell http://purl.obolibrary.org/obo/CL_0000703 sustentacular cell A densely staining taste receptor cell that contains many dense vacuoles in their apical regions which project into the apical space and bear microvilli. This cell type serves as a supporting cell by surrounding and isolating the other cell types from each other; secrete a dense amorphous material that surrounds the microvilli in the taste pore. This cell type expresses a glial glutumate transporter, GLAST. http://purl.obolibrary.org/obo/GO_0021610 facial nerve morphogenesis http://purl.obolibrary.org/obo/GO_0021602 cranial nerve morphogenesis The process in which the anatomical structure of the facial nerve is generated and organized. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial ophthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities. http://purl.obolibrary.org/obo/CL_0002290 Y chromosome-bearing sperm cell http://purl.obolibrary.org/obo/CL_0000019 sperm A sperm bearing a Y chromosome. Chromosomal and genetic sex is established at fertilization in mammals and depends upon whether an X-bearing sperm or a Y-bearing sperm fertilizes the X-bearing ovum. http://purl.obolibrary.org/obo/GO_0021611 facial nerve formation http://purl.obolibrary.org/obo/GO_0021603 cranial nerve formation The process that gives rise to the facial nerve. This process pertains to the initial formation of a structure from unspecified parts. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial ophthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities. http://purl.obolibrary.org/obo/CL_0002291 X chromosome-bearing sperm cell http://purl.obolibrary.org/obo/CL_0000019 sperm A sperm bearing an X chromosome. Chromosomal and genetic sex is established at fertilization in mammals and depends upon whether an X-bearing sperm or a Y-bearing sperm fertilizes the X-bearing ovum. http://purl.obolibrary.org/obo/CL_0002292 type I cell of carotid body http://purl.obolibrary.org/obo/CL_0000710 neurecto-epithelial cell A round or oval neuroepithelial cell that contacts other type I cells or capillaries. They occur in clusters that are surrounded by sheath cells (type-II cells) in the carotid body. This cell type is capable of secreting a number of neurotransmitters. http://purl.obolibrary.org/obo/GO_0021613 facial nerve maturation http://purl.obolibrary.org/obo/GO_0021605 cranial nerve maturation A developmental process, independent of morphogenetic (shape) change, that is required for the facial nerve to attain its fully functional state. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial ophthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities. http://purl.obolibrary.org/obo/CL_0002293 epithelial cell of thymus http://purl.obolibrary.org/obo/CL_0002076 endo-epithelial cell An epithelial cell of the thymus. Epithelial reticular cells are pleomorphic, stellate, non-phagocytic cells which seem to be supportive in function and are held together by desmosomes. They replace the fibroblastoid reticular cells found in other lymphoid organs. Other epithelial cells in the medulla have the ultrastructure of secretory cells. Although different epithelial cells throughout the thymus appear alike by light microscopy their ultrastructure and function varies. http://purl.obolibrary.org/obo/GO_0021614 glossopharyngeal nerve maturation http://purl.obolibrary.org/obo/GO_0021605 cranial nerve maturation A developmental process, independent of morphogenetic (shape) change, that is required for the glossopharyngeal nerve to attain its fully functional state. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion. http://purl.obolibrary.org/obo/CL_0002294 type-1 epithelial cell of thymus http://purl.obolibrary.org/obo/CL_0002364 cortical thymic epithelial cell An epithelial cell with a well defined Golgi apparatus that makes up the continuous layer of cells bordering the thymic tissue beneath the capsule. http://purl.obolibrary.org/obo/CL_0002295 type-6 epithelial cell of thymus http://purl.obolibrary.org/obo/CL_0002365 medullary thymic epithelial cell A thymic epithelial cell that has an eccentric, round, or irregularly shaped hetero or euchromatic nucleus. The hallmark of this cell type is the presence of vacuoles, which are clustered in one area of the cytoplasm in the vicinity of the nucleus. The vacuoles are small and acquire a grape-like form, occasionally showing delicate internal microvillous projections. http://purl.obolibrary.org/obo/GO_0021615 glossopharyngeal nerve morphogenesis http://purl.obolibrary.org/obo/GO_0021602 cranial nerve morphogenesis The process in which the anatomical structure of the glossopharyngeal nerve is generated and organized. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion. http://purl.obolibrary.org/obo/CL_0002296 type-4 epithelial cell of thymus http://purl.obolibrary.org/obo/CL_0002365 medullary thymic epithelial cell An epithelial cell with high nuclear and cytoplasmic electron-density. This cell type is found in the deeper portions of the cortex but is more abundant in the medulla of the thymus. http://purl.obolibrary.org/obo/CL_0002297 type-3 epithelial cell of thymus http://purl.obolibrary.org/obo/CL_0002364 cortical thymic epithelial cell A thymic epithelial cell with moderate nuclear and cytoplasmic electron-density. Scattered in the cortex, this cell type is predominant in the mid and deep cortex. http://purl.obolibrary.org/obo/GO_0021616 glossopharyngeal nerve formation http://purl.obolibrary.org/obo/GO_0021603 cranial nerve formation The process that gives rise to the glossopharyngeal nerve. This process pertains to the initial formation of a structure from unspecified parts. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion. http://purl.obolibrary.org/obo/CL_0002298 type-5 epithelial cell of thymus http://purl.obolibrary.org/obo/CL_0002365 medullary thymic epithelial cell A thymic epithelial cell type with low nuclear and cytoplasmic electrondensity; has a round, euchromatic nucleus and occurs in small groups at the corticomedullary junction or scattered singly in the medulla. http://purl.obolibrary.org/obo/CL_0002299 type-2 epithelial cell of thymus http://purl.obolibrary.org/obo/CL_0002364 cortical thymic epithelial cell An epithelial cell scattered in the cortex, predominant in the outer cortex with a large pale nucleus and a prominent nucleolus. http://purl.obolibrary.org/obo/GO_0021618 hypoglossal nerve morphogenesis http://purl.obolibrary.org/obo/GO_0021602 cranial nerve morphogenesis The process in which the anatomical structure of the hypoglossal nerve is generated and organized. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue. http://purl.obolibrary.org/obo/CL_0002300 type-7 epithelial cell of thymus http://purl.obolibrary.org/obo/CL_0002365 medullary thymic epithelial cell A small medullary thymic epithelial cell with a spindle shape, often arranged in groups and connected to each other by large desmosomes and interdigitations. The cytoplasm is sparse, with scanty organelles and thick bundles of cytokeratin. http://purl.obolibrary.org/obo/CL_0002301 type B synovial cell http://purl.obolibrary.org/obo/CL_0000499 stromal cell A resident stromal cell located in the synovial membrane and responsible for the production of immune-related cytokines and chemokines. This cell type secretes glycoproteins and hyaluronic acid, has abundant granular endoplasmic reticulum, but contains fewer vacuoles and vesicles. http://purl.obolibrary.org/obo/GO_0021619 hypoglossal nerve maturation http://purl.obolibrary.org/obo/GO_0021605 cranial nerve maturation A developmental process, independent of morphogenetic (shape) change, that is required for the hypoglossal nerve to attain its fully functional state. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue. http://purl.obolibrary.org/obo/CL_0002302 type A synovial cell http://purl.obolibrary.org/obo/CL_0000234 phagocyte A synovial cell that is macrophage-like, characterized by surface ruffles or lamellipodia, plasma membrane invaginations and associated micropinocytotic vesicles, Golgi apparatus and little granular endoplasmic reticulum. http://purl.obolibrary.org/obo/CL_0002303 pigmented ciliary epithelial cell http://purl.obolibrary.org/obo/CL_0000529 pigmented epithelial cell A cell that is part of pigmented ciliary epithelium. This cell type uptakes sodium and chloride ions from stromal interstitium and passes the ions to non-pigmented ciliary epithelial cells via gap junctions. http://purl.obolibrary.org/obo/GO_0021620 hypoglossal nerve formation http://purl.obolibrary.org/obo/GO_0021603 cranial nerve formation The process that gives rise to the hypoglossal nerve. This process pertains to the initial formation of a structure from unspecified parts. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue. http://purl.obolibrary.org/obo/CL_0002304 non-pigmented ciliary epithelial cell http://purl.obolibrary.org/obo/CL_0000710 neurecto-epithelial cell A cell that is part of non-pigmented ciliary epithelium. This cell type participates in aqueous humor formation by releasing solute, principally sodium and chloride ions received from pigmented epithelial cells via gap junctions, into the aqueous humor of the eye. http://purl.obolibrary.org/obo/CL_0002305 epithelial cell of distal tubule http://purl.obolibrary.org/obo/CL_1000615 kidney cortex tubule cell An epithelial cell of the distal convoluted tubule of the kidney that helps regulate systemic levels of potassium, sodium, calcium, and pH. http://purl.obolibrary.org/obo/GO_0021622 oculomotor nerve morphogenesis http://purl.obolibrary.org/obo/GO_0021602 cranial nerve morphogenesis The process in which the anatomical structure of the oculomotor nerve is generated and organized. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle. http://purl.obolibrary.org/obo/CL_0002306 epithelial cell of proximal tubule http://purl.obolibrary.org/obo/CL_1000615 kidney cortex tubule cell An epithelial cell of the proximal tubule of the kidney. http://purl.obolibrary.org/obo/GO_0021623 oculomotor nerve formation http://purl.obolibrary.org/obo/GO_0021603 cranial nerve formation The process that gives rise to the oculomotor nerve. This process pertains to the initial formation of a structure from unspecified parts. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle. http://purl.obolibrary.org/obo/CL_0002307 brush border cell of the proximal tubule http://purl.obolibrary.org/obo/CL_0002306 epithelial cell of proximal tubule A brush border epithelial cell located in the proximal tubule of the kidney, essential for reabsorbing substances like glucose and amino acids from the glomerular filtrate. These cells also secrete organic ions, playing a crucial role in maintaining kidney homeostasis, including electrolyte and acid-base balance, and excreting metabolic waste. http://purl.obolibrary.org/obo/CL_0002308 epithelial cell of skin gland http://purl.obolibrary.org/obo/CL_0002159 general ecto-epithelial cell An epithelial cell of a skin gland. http://purl.obolibrary.org/obo/GO_0021625 oculomotor nerve maturation http://purl.obolibrary.org/obo/GO_0021605 cranial nerve maturation A developmental process, independent of morphogenetic (shape) change, that is required for the oculomotor nerve to attain its fully functional state. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle. http://purl.obolibrary.org/obo/CL_0002309 corticotroph http://purl.obolibrary.org/obo/CL_0000639 basophil cell of pars distalis of adenohypophysis A basophil chromphil cell of the anterior pitiutary gland that produce adrenocorticotropic hormone, melanocyte-stimulating hormone and lipotropin. This cell type is irregular in shape and has short dendritic processes which are inserted among other neighboring cells; http://purl.obolibrary.org/obo/GO_0021626 central nervous system maturation http://purl.obolibrary.org/obo/GO_0071695 anatomical structure maturation A developmental process, independent of morphogenetic (shape) change, that is required for the central nervous system to attain its fully functional state. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord. http://purl.obolibrary.org/obo/CL_0002310 mammosomatotroph http://purl.obolibrary.org/obo/CL_0000638 acidophil cell of pars distalis of adenohypophysis An acidophil cell of the anterior pituitary gland that produces both prolactin and growth hormone. http://purl.obolibrary.org/obo/CL_0002311 mammotroph http://purl.obolibrary.org/obo/CL_0000638 acidophil cell of pars distalis of adenohypophysis An acidophilic cell of the anterior pituitary that produces prolactin. http://purl.obolibrary.org/obo/GO_0021627 olfactory nerve morphogenesis http://purl.obolibrary.org/obo/GO_0021602 cranial nerve morphogenesis The process in which the anatomical structure of the olfactory nerve is generated and organized. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem. http://purl.obolibrary.org/obo/CL_0002312 somatotroph http://purl.obolibrary.org/obo/CL_0000638 acidophil cell of pars distalis of adenohypophysis An acidophilic cell of the anterior pituitary that produces growth hormone, somatotropin. http://purl.obolibrary.org/obo/CL_0002313 endocrine-paracrine cell of prostate gland http://purl.obolibrary.org/obo/CL_0002159 general ecto-epithelial cell An ecto-epithelial cell of the prostate gland that secretes hormones. http://purl.obolibrary.org/obo/GO_0021628 olfactory nerve formation http://purl.obolibrary.org/obo/GO_0021603 cranial nerve formation The process that gives rise to the olfactory nerve. This process pertains to the initial formation of a structure from unspecified parts. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem. http://purl.obolibrary.org/obo/CL_0002314 external supporting cell of vestibular epithelium http://purl.obolibrary.org/obo/CL_0002316 supporting cell of vestibular epithelium An auditory epithelial support cell located in the vestibular epithelium that has many hallmarks of glial cells. This cell type express glial markers such as vimentin, S100, glutamate-aspartate transporter, low affinity neurotrophin receptor p75, glial fibrillary acidic protein, and proteolipid protein. http://purl.obolibrary.org/obo/CL_0002315 supporting cell of cochlea http://purl.obolibrary.org/obo/CL_0005014 auditory epithelial supporting cell An epithelial supporting cell located in the cochlea. http://purl.obolibrary.org/obo/GO_0021630 olfactory nerve maturation http://purl.obolibrary.org/obo/GO_0021605 cranial nerve maturation A developmental process, independent of morphogenetic (shape) change, that is required for the olfactory nerve to attain its fully functional state. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem. http://purl.obolibrary.org/obo/CL_0002316 supporting cell of vestibular epithelium http://purl.obolibrary.org/obo/CL_0005014 auditory epithelial supporting cell A supporting cell of the vestibular epithelium. http://purl.obolibrary.org/obo/GO_0021631 optic nerve morphogenesis http://purl.obolibrary.org/obo/GO_0021602 cranial nerve morphogenesis The process in which the anatomical structure of the optic nerve is generated and organized. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain. http://purl.obolibrary.org/obo/CL_0002317 external limiting cell of vestibular epithelium http://purl.obolibrary.org/obo/CL_0002316 supporting cell of vestibular epithelium An external limiting cell found in the vestibular epithelium. http://purl.obolibrary.org/obo/CL_0002318 peripheral blood mesothelial cell http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell A mesothelial cell capable of circulating in the blood by first losing its squamous character. This cell can incorporate into the regenerating mesothelium. http://purl.obolibrary.org/obo/GO_0021632 optic nerve maturation http://purl.obolibrary.org/obo/GO_0021605 cranial nerve maturation A developmental process, independent of morphogenetic (shape) change, that is required for the optic nerve to attain its fully functional state. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain. http://purl.obolibrary.org/obo/CL_0002319 neural cell http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell A cell that is part of the nervous system. http://purl.obolibrary.org/obo/CL_0002320 connective tissue cell http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell A cell of the supporting or framework tissue of the body, which includes adipose tissue, cartilage, and bone. In vertebrates, this cell arises chiefly from the embryonic mesoderm and, in cranial regions, from neural crest. http://purl.obolibrary.org/obo/GO_0021634 optic nerve formation http://purl.obolibrary.org/obo/GO_0021603 cranial nerve formation The process that gives rise to the optic nerve. This process pertains to the initial formation of a structure from unspecified parts. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain. http://purl.obolibrary.org/obo/CL_0002321 embryonic cell (metazoa) http://purl.obolibrary.org/obo/CL_0000000 cell A cell of the embryo. http://purl.obolibrary.org/obo/CL_0002322 embryonic stem cell http://purl.obolibrary.org/obo/CL_0002321 embryonic cell (metazoa) A stem cell of embryonic origin. http://purl.obolibrary.org/obo/GO_0021635 trigeminal nerve maturation http://purl.obolibrary.org/obo/GO_0021605 cranial nerve maturation A developmental process, independent of morphogenetic (shape) change, that is required for the trigeminal nerve to attain its fully functional state. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae. http://purl.obolibrary.org/obo/CL_0002324 basal-myoepithelial cell of mammary gland http://purl.obolibrary.org/obo/CL_0002327 mammary gland epithelial cell A myoepithelial cell that is part of a mammary gland and is located in the basal layer. During lactation, a basal-myoepithelial cell of mammary gland contracts under the stimulation of oxytocin. In humans, a basal-myoepithelial cell of mammary gland can be identified by high levels of CD49f and low levels of EpCAM. http://purl.obolibrary.org/obo/CL_0002325 lactocyte http://purl.obolibrary.org/obo/CL_1001586 mammary gland glandular cell A milk-producing glandular epithelial cell that is part of a mammary gland alveolus and differentiates from a luminal adaptive secretory precursor cell during secretory differentiation (also termed lactogenesis I). Following secretory activation (also termed lactogenesis II), a lactocyte is involved in the synthesis and/or transport of milk constituents including proteins, oligosaccharides, lactose, micronutrients, fat, hormones, immunoglobulins, and cytokines into the lumen of the lactating mammary gland. http://purl.obolibrary.org/obo/GO_0021636 trigeminal nerve morphogenesis http://purl.obolibrary.org/obo/GO_0021602 cranial nerve morphogenesis The process in which the anatomical structure of the trigeminal nerve is generated and organized. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae. http://purl.obolibrary.org/obo/CL_0002326 luminal epithelial cell of mammary gland http://purl.obolibrary.org/obo/CL_0002327 mammary gland epithelial cell A mammary epithelial cell that occurs in the lumen of the ductal and alveoli structure in the breast. http://purl.obolibrary.org/obo/CL_0002327 mammary gland epithelial cell http://purl.obolibrary.org/obo/CL_0000066 epithelial cell An epithelial cell of the mammary gland. http://purl.obolibrary.org/obo/GO_0021638 trigeminal nerve formation http://purl.obolibrary.org/obo/GO_0021603 cranial nerve formation The process that gives rise to the trigeminal nerve. This process pertains to the initial formation of a structure from unspecified parts. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae. http://purl.obolibrary.org/obo/CL_0002328 bronchial epithelial cell http://purl.obolibrary.org/obo/CL_0002202 epithelial cell of tracheobronchial tree An epithelial cell of the bronchus. http://purl.obolibrary.org/obo/CL_0002329 basal epithelial cell of tracheobronchial tree http://purl.obolibrary.org/obo/CL_0002202 epithelial cell of tracheobronchial tree An epithelial cell type that lacks the columnar shape typical for other respiratory epithelial cells. This cell type is able to differentiate into other respiratory epithelial cells in response to injury. http://purl.obolibrary.org/obo/GO_0021643 vagus nerve maturation http://purl.obolibrary.org/obo/GO_0021605 cranial nerve maturation A developmental process, independent of morphogenetic (shape) change, that is required for the vagus nerve to attain its fully functional state. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis. http://purl.obolibrary.org/obo/CL_0002330 undifferentiated cell of bronchus epithelium http://purl.obolibrary.org/obo/CL_0002328 bronchial epithelial cell An undifferentiated columnar cell of the bronchus epithelium http://purl.obolibrary.org/obo/CL_0002332 multiciliated epithelial cell of the bronchus http://purl.obolibrary.org/obo/CL_0002328 bronchial epithelial cell A multi-ciliated epithelial cell located in the bronchus epithelium, characterized by a columnar shape and motile cilia on its apical surface. http://purl.obolibrary.org/obo/GO_0021644 vagus nerve morphogenesis http://purl.obolibrary.org/obo/GO_0021602 cranial nerve morphogenesis The process in which the anatomical structure of the vagus nerve is generated and organized. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis. http://purl.obolibrary.org/obo/CL_0002333 neural crest derived adipocyte http://purl.obolibrary.org/obo/CL_0000136 adipocyte An adipocyte derived from a neural crest cell. http://purl.obolibrary.org/obo/CL_0002334 preadipocyte http://purl.obolibrary.org/obo/CL_0000057 fibroblast An undifferentiated fibroblast that can be stimulated to form a fat cell. http://purl.obolibrary.org/obo/GO_0021646 vagus nerve formation http://purl.obolibrary.org/obo/GO_0021603 cranial nerve formation The process that gives rise to the vagus nerve. This process pertains to the initial formation of a structure from unspecified parts. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis. http://purl.obolibrary.org/obo/CL_0002335 brown preadipocyte http://purl.obolibrary.org/obo/CL_0002334 preadipocyte A preadipocyte that is capable of differentiating into a brown adipocyte. This cell type expresses uncoupling protein-1, PPAR-gamma, PR-domain-containing 16; and PGC-1alpha (peroxisome proliferator-activated receptor-gamma (PPARgamma) coactivator-1alpha). http://purl.obolibrary.org/obo/CL_0002336 buccal mucosa cell http://purl.obolibrary.org/obo/CL_0002261 endothelial cell of viscerocranial mucosa An endothelial cell that lines the oral cavitiy including the mucosa of the gums, the palate, the lip, and the cheek. http://purl.obolibrary.org/obo/GO_0021647 vestibulocochlear nerve maturation http://purl.obolibrary.org/obo/GO_0021605 cranial nerve maturation A developmental process, independent of morphogenetic (shape) change, that is required for the vestibulocochlear nerve to attain its fully functional state. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea. http://purl.obolibrary.org/obo/CL_0002337 keratinocyte stem cell http://purl.obolibrary.org/obo/CL_0011026 progenitor cell A stem cell found in the basal layer of the epidermis, hair follicle, and sebaceous gland, characterised by its quiescent nature, high proliferative potential, and capacity for long-term self-renewal. This cell maintains epidermal homeostasis by producing transit-amplifying cells that differentiate to replenish the stratified squamous epithelium. http://purl.obolibrary.org/obo/GO_0021648 vestibulocochlear nerve morphogenesis http://purl.obolibrary.org/obo/GO_0021602 cranial nerve morphogenesis The process in which the anatomical structure of the vestibulocochlear nerve is generated and organized. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea. http://purl.obolibrary.org/obo/CL_0002338 CD56-positive, CD161-positive immature natural killer cell, human http://purl.obolibrary.org/obo/CL_0000823 immature natural killer cell A natural killer cell that is developmentally immature, has the phenotype CD34-negative, CD56-positive, CD117-positive, CD122-positive,and CD161-positive. http://purl.obolibrary.org/obo/GO_0021650 vestibulocochlear nerve formation http://purl.obolibrary.org/obo/GO_0021603 cranial nerve formation The process that gives rise to the vestibulocochlear nerve. This process pertains to the initial formation of a structure from unspecified parts. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea. http://purl.obolibrary.org/obo/CL_0002339 prostate stem cell http://purl.obolibrary.org/obo/CL_0002341 basal cell of prostate epithelium A prostate epithelial cell that is CD133-positive, CD44-positive, integrin A2beta3-high. This cell is a stem cell for the prostate epithelium. http://purl.obolibrary.org/obo/CL_0002340 luminal cell of prostate epithelium http://purl.obolibrary.org/obo/CL_0002231 epithelial cell of prostate The exocrine cell of the prostate, this epithelial cell secretes prostatic acid phosphotase and PSA, and is dependent on androgen hormones for survival. http://purl.obolibrary.org/obo/GO_0021651 rhombomere 1 morphogenesis http://purl.obolibrary.org/obo/GO_0021593 rhombomere morphogenesis The process in which the anatomical structure of rhombomere 1 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order. http://purl.obolibrary.org/obo/CL_0002341 basal cell of prostate epithelium http://purl.obolibrary.org/obo/CL_0002231 epithelial cell of prostate An undifferentiated cell of the prostate epithelium that lacks secretory activity. http://purl.obolibrary.org/obo/GO_0021652 rhombomere 1 formation http://purl.obolibrary.org/obo/GO_0021594 rhombomere formation The process that gives rise to rhombomere 1. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order. http://purl.obolibrary.org/obo/CL_0002342 circulating endothelial cell http://purl.obolibrary.org/obo/CL_0000115 endothelial cell A circulating endothelial cell of the phenotype CD146-positive, CD105-positive, CD45-negative. This cell type is indicative of recent vascular damage. http://purl.obolibrary.org/obo/CL_0002343 decidual natural killer cell, human http://purl.obolibrary.org/obo/CL_0000824 mature natural killer cell A natural killer cell subset that is found in the decidual of the uterus and is CD56-high, Galectin-1-positive and CD16-negative. This cell type represents the most abundant immune cell type in the decidual during the first trimester of pregnancy. http://purl.obolibrary.org/obo/GO_0021654 rhombomere boundary formation http://purl.obolibrary.org/obo/GO_0048859 formation of anatomical boundary The process that gives rise to a rhombomere boundary. This process pertains to the initial formation of a boundary delimiting a rhombomere. Rhombomeres are transverse segments of the developing rhombencephalon that are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order. http://purl.obolibrary.org/obo/CL_0002344 CD56-negative, CD161-positive immature natural killer cell, human http://purl.obolibrary.org/obo/CL_0000823 immature natural killer cell A natural killer cell that is developmentally immature, has the phenotype CD34-negative, CD56-negative, CD117-positive, CD122-positive,and CD161-positive. http://purl.obolibrary.org/obo/CL_0002345 CD27-low, CD11b-low immature natural killer cell, mouse http://purl.obolibrary.org/obo/CL_0000823 immature natural killer cell An immature natural killer cell that is NK1.1-positive, DX5-positive, Ly49-positive, CD27-low and CD11b-low. This cell type is found in high numbers in the liver. http://purl.obolibrary.org/obo/GO_0021670 lateral ventricle development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the lateral ventricles over time, from the formation to the mature structure. The two lateral ventricles are a cavity in each of the cerebral hemispheres derived from the cavity of the embryonic neural tube. They are separated from each other by the septum pellucidum, and each communicates with the third ventricle by the foramen of Monro, through which also the choroid plexuses of the lateral ventricles become continuous with that of the third ventricle. http://purl.obolibrary.org/obo/CL_0002346 Dx5-negative, NK1.1-positive immature natural killer cell, mouse http://purl.obolibrary.org/obo/CL_0000823 immature natural killer cell An immature natural killer cell that is NK1.1-positive and DX-5 negative. http://purl.obolibrary.org/obo/CL_0002347 CD27-high, CD11b-high natural killer cell, mouse http://purl.obolibrary.org/obo/CL_0000824 mature natural killer cell A mature natural killer cell that is CD27-high and CD11b-high. This cell type is capable of interferon-gamma secretion. http://purl.obolibrary.org/obo/GO_0021675 nerve development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of a nerve over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/CL_0002348 CD27-low, CD11b-high natural killer cell, mouse http://purl.obolibrary.org/obo/CL_0000824 mature natural killer cell A CD27-low, CD11b-high natural killer cell that has a higher threshold of activation due to higher expression of inhibitory receptors. http://purl.obolibrary.org/obo/CL_0002349 CD27-high, CD11b-low natural killer cell, mouse http://purl.obolibrary.org/obo/CL_0000824 mature natural killer cell A natural killer cell that is CD27-high and CD11b-low. http://purl.obolibrary.org/obo/GO_0021678 third ventricle development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the third ventricle over time, from its formation to the mature structure. The third ventricle is the narrow cleft inferior to the corpus callosum, within the diencephalon, between the paired thalami. Its floor is formed by the hypothalamus, its anterior wall by the lamina terminalis, and its roof by ependyma, and it communicates with the fourth ventricle by the cerebral aqueduct, and with the lateral ventricles by the interventricular foramina. http://purl.obolibrary.org/obo/CL_0002350 endocardial cell http://purl.obolibrary.org/obo/CL_0010008 cardiac endothelial cell An endothelial cell that lines the intracavitary lumen of the heart, separating the circulating blood from the underlying myocardium. This cell type releases a number of vasoactive substances including prostacyclin, nitrous oxide and endothelin. http://purl.obolibrary.org/obo/CL_0002351 progenitor cell of endocrine pancreas http://purl.obolibrary.org/obo/CL_0011026 progenitor cell A progenitor cell that is able to differentiate into the pancreas alpha, beta and delta endocrine cells. This cell type expresses neurogenin-3 and Isl-1. http://purl.obolibrary.org/obo/GO_0021679 cerebellar molecular layer development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the cerebellar molecular layer nerve over time, from its formation to the mature structure. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells. http://purl.obolibrary.org/obo/CL_0002352 gestational hematopoietic stem cell http://purl.obolibrary.org/obo/CL_0000037 hematopoietic stem cell A hematopoietic stem cell that exists during embryogenesis. http://purl.obolibrary.org/obo/CL_0002353 fetal liver hematopoietic progenitor cell http://purl.obolibrary.org/obo/CL_0002352 gestational hematopoietic stem cell A hematopoietic stem cell that resides in the fetal liver. In mice, this cell type is first observed at E10.5. This cell type is MHC-positive, HSA-positive, AA4.1-positive, CD45-positive, Sca-1 positive, CD150-positive, CD48-negative and CD244-negative. http://purl.obolibrary.org/obo/GO_0021680 cerebellar Purkinje cell layer development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the cerebellar Purkinje cell layer over time, from its formation to the mature structure. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells. http://purl.obolibrary.org/obo/CL_0002354 yolk sac hematopoietic stem cell http://purl.obolibrary.org/obo/CL_0002352 gestational hematopoietic stem cell A hematopoietic stem found in the yolk sac. In mice, this cell type is Sca-1-negative, CD45-negative, MHC-negative, HSA-positive, AA4.1-positive, CD44-positive. http://purl.obolibrary.org/obo/CL_0002355 primitive red blood cell http://purl.obolibrary.org/obo/CL_0002417 primitive erythroid lineage cell A large nucleated basophilic erythrocyte found in mammalian embryos. This cell type arises from the blood islands of yolk sacs and expresses different types of hemoglobins (beta-H1, gamma-1 and zeta) than adult erythrocytes. Considered a type of erythroblast as this cell type can enucleate in circulation. http://purl.obolibrary.org/obo/GO_0021681 cerebellar granular layer development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the cerebellar granule layer over time, from its formation to the mature structure. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer. http://purl.obolibrary.org/obo/CL_0002356 primitive reticulocyte http://purl.obolibrary.org/obo/CL_0002417 primitive erythroid lineage cell A primitive erythrocyte that has undergone enucleation. This cell type is 3-6 fold bigger than the fetal derived erythrocytes that they co-circulate with during fetal development. Expresses epsilon-gamma hemoglobin chains. http://purl.obolibrary.org/obo/GO_0021682 nerve maturation http://purl.obolibrary.org/obo/GO_0071695 anatomical structure maturation A developmental process, independent of morphogenetic (shape) change, that is required for a nerve to attain its fully functional state. http://purl.obolibrary.org/obo/CL_0002357 fetal derived definitive erythrocyte http://purl.obolibrary.org/obo/CL_0000595 enucleate erythrocyte A fetal liver derived enucleated erythrocyte. This erythrocyte resembles adult erythrocytes in that they are small (3- to 6- times smaller than primitive erythrocytes) and produce adult hemaglobins. http://purl.obolibrary.org/obo/CL_0002358 pyrenocyte http://purl.obolibrary.org/obo/CL_0002417 primitive erythroid lineage cell Derived from the Greek word pyren (the pit of a stone fruit), this is a transient nucleated cell type that results from exclusion of the nucleus from the primitive erythrocyte. http://purl.obolibrary.org/obo/GO_0021683 cerebellar granular layer morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structure of the cerebellar granular layer is generated and organized. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer. http://purl.obolibrary.org/obo/CL_0002359 placental hematopoietic stem cell http://purl.obolibrary.org/obo/CL_0002352 gestational hematopoietic stem cell A hematopoietic stem cell of the placenta. This cell type is first observed E10.5 This cell type may give rise to fetal liver hematopoietic stem cells. http://purl.obolibrary.org/obo/CL_0002360 AGM hematopoietic stem cell http://purl.obolibrary.org/obo/CL_0002352 gestational hematopoietic stem cell A hematopoietic stem cell from the aorta-gonad-mesonephros region of the developing embryo. First seen at E10.5 in mouse embryos. May give rise to fetal liver HSC. http://purl.obolibrary.org/obo/GO_0021684 cerebellar granular layer formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process that gives rise to the cerebellar granule layer. This process pertains to the initial formation of a structure from unspecified parts. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer. http://purl.obolibrary.org/obo/CL_0002361 primitive erythroid progenitor http://purl.obolibrary.org/obo/CL_0002417 primitive erythroid lineage cell A progenitor cell that is capable of forming colonies of primitive erythrocytes in the blood island of the yolk sac. First arrive at E7.5 in mouse and expresses CD41. http://purl.obolibrary.org/obo/GO_0021686 cerebellar granular layer maturation http://purl.obolibrary.org/obo/GO_0071695 anatomical structure maturation A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar granular layer to attain its fully functional state. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer. http://purl.obolibrary.org/obo/CL_0002362 cerebellar granule cell precursor http://purl.obolibrary.org/obo/CL_0002319 neural cell A cell located in the outermost proliferative zone of the external germinal layer that can differentiate into astroglial cells and granule cells. This cell type is glial fibrillary acidic protein-positive and HNK1-positive. http://purl.obolibrary.org/obo/CL_0002363 keratocyte http://purl.obolibrary.org/obo/CL_0000005 neural crest derived fibroblast A keratocyte is a specialized fibroblast residing in the cornea stroma that has a flattened, dendritic morphology; located between the lamellae with a large flattened nucleus, and lengthy processes which communicate with neighboring cells. This corneal layer, representing about 85-90% of corneal thickness, is built up from highly regular collagenous lamellae and extracellular matrix components. Keratocytes play the major role in keeping it transparent, healing its wounds, and synthesizing its components. This cell type secretes collagen I, V, VI, and keratan sulfate. http://purl.obolibrary.org/obo/GO_0021687 cerebellar molecular layer morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structure of the cerebellar molecular layer is generated and organized. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells. http://purl.obolibrary.org/obo/CL_0002364 cortical thymic epithelial cell http://purl.obolibrary.org/obo/CL_0002293 epithelial cell of thymus An epithelial cell of the cortical portion of the thymus. Epithelial cells in this region are required for positive selection of CD8-positive T cells. http://purl.obolibrary.org/obo/CL_0002365 medullary thymic epithelial cell http://purl.obolibrary.org/obo/CL_0002293 epithelial cell of thymus An epithelial cell of the medullary thymus. This cell type expresses a diverse range of tissue-specific antigens. This promiscuous gene expression is a cell-autonomous property of medullary epithelial cells and is maintained during the entire period of thymic T cell output. http://purl.obolibrary.org/obo/CL_0002366 myometrial cell http://purl.obolibrary.org/obo/CL_0002601 uterine smooth muscle cell A smooth muscle cell of the myometrium that enlarges and stretches during pregnancy, and contracts in response to oxytocin. http://purl.obolibrary.org/obo/GO_0021688 cerebellar molecular layer formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process that gives rise to the cerebellar molecular layer. This process pertains to the initial formation of a structure from unspecified parts. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells. http://purl.obolibrary.org/obo/CL_0002367 trabecular meshwork cell http://purl.obolibrary.org/obo/CL_0002320 connective tissue cell An ocular connective tissue cell that is part of the eye's trabecular meshwork and is directly responsible for regulating the outflow of aqueous humor from the anterior chamber of the eye, thereby maintaining proper intraocular pressure. http://purl.obolibrary.org/obo/CL_0002368 respiratory tract epithelial cell http://purl.obolibrary.org/obo/CL_0002076 endo-epithelial cell An epithelial cell of the respiratory tract epithelium. These cells have an endodermal origin. http://purl.obolibrary.org/obo/GO_0021690 cerebellar molecular layer maturation http://purl.obolibrary.org/obo/GO_0071695 anatomical structure maturation A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar molecular layer to attain its fully functional state. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells. http://purl.obolibrary.org/obo/CL_0002369 fungal spore http://purl.obolibrary.org/obo/CL_0000521 fungal cell A differentiated form of a fungus produced during or as a result of an asexual or sexual reproductive process; usually a cell with a thick cell wall that stores and protects one or more nuclei. Spores may be produced in response to, and are characteristically resistant to, adverse environmental conditions. http://purl.obolibrary.org/obo/CL_0002370 respiratory tract goblet cell http://purl.obolibrary.org/obo/CL_0008055 respiratory tract secretory epithelial cell A simple columnar epithelial cell that secretes mucin. Rough endoplasmic reticulum, mitochondria, the nucleus, and other organelles are concentrated in the basal portion. The apical plasma membrane projects microvilli to increase surface area for secretion. http://purl.obolibrary.org/obo/GO_0021691 cerebellar Purkinje cell layer maturation http://purl.obolibrary.org/obo/GO_0071695 anatomical structure maturation A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar Purkinje cell layer to attain its fully functional state. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells. http://purl.obolibrary.org/obo/CL_0002372 myotube http://purl.obolibrary.org/obo/CL_0000737 striated muscle cell A transversely striated, multinucleated syncytial muscle cell, formed by the fusion of myoblasts during muscle development. http://purl.obolibrary.org/obo/CL_0002373 growth hormone releasing hormone secreting cell http://purl.obolibrary.org/obo/CL_0000167 peptide hormone secreting cell A peptide hormone secreting cell that secretes growth hormone releasing hormone. http://purl.obolibrary.org/obo/GO_0021692 cerebellar Purkinje cell layer morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structure of the cerebellar Purkinje cell layer is generated and organized. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells. http://purl.obolibrary.org/obo/CL_0002374 ear hair cell http://purl.obolibrary.org/obo/CL_0000855 sensory hair cell A hair cell of the ear that contains the organs of balance and hearing. http://purl.obolibrary.org/obo/GO_0021694 cerebellar Purkinje cell layer formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process that gives rise to the cerebellar Purkinje cell layer. This process pertains to the initial formation of a structure from unspecified parts. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells. http://purl.obolibrary.org/obo/CL_0002375 Schwann cell precursor http://purl.obolibrary.org/obo/CL_0011026 progenitor cell A multipotent progenitor cell that develops from a migratory neural crest cell. The schwann cell precursor is embedded among axons, with minimal extracellular space separating them from nerve cell membranes. This cell lacks a basal lamina, which distinguishes it from more mature Schwann cells. In rodents, cadherin-19 (Cdh19) serves as a specific marker for this developmental stage. http://purl.obolibrary.org/obo/CL_0002376 non-myelinating Schwann cell http://purl.obolibrary.org/obo/CL_0002573 Schwann cell A glial cell that ensheaths multiple small diameter axons in the peripheral nervous system. The non-myelinating Schwann cell is embedded among neurons (axons) with minimal extracellular spaces separating them from nerve cell membranes and has a basal lamina. Cells can survive without an axon present. These cells can de-differentiate into immature Schwann cells. http://purl.obolibrary.org/obo/GO_0021695 cerebellar cortex development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the cerebellar cortex over time, from its formation to the mature structure. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function. http://purl.obolibrary.org/obo/CL_0002377 immature Schwann cell http://purl.obolibrary.org/obo/CL_0002573 Schwann cell A glial cell that develops from a Schwann cell precursor. The immature Schwann cell is embedded among neurons (axons) with minimal extracellular spaces separating them from nerve cell membranes and has a basal lamina. Cells can survive without an axon present. Immature Schwann cell can be found communally ensheathing large groups of axons. http://purl.obolibrary.org/obo/CL_0002378 immature Vgamma2-positive fetal thymocyte http://purl.obolibrary.org/obo/CL_0002404 fetal thymocyte A double negative thymocyte that has a T cell receptor consisting of a gamma chain containing a Vgamma2 segment, and a delta chain. This cell type is CD4-negative, CD8-negative and CD24-positive and is found in the fetal thymus. http://purl.obolibrary.org/obo/GO_0021696 cerebellar cortex morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structure of the cranial nerves are generated and organized. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function. http://purl.obolibrary.org/obo/CL_0002379 meningothelial cell http://purl.obolibrary.org/obo/CL_0000710 neurecto-epithelial cell A neurecto-epithelial cell found in the arachnoid villi of dura mater. This cell type facilitates flow of cerebrospinal fluid into the blood. http://purl.obolibrary.org/obo/GO_0021697 cerebellar cortex formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process that gives rise to the cerebellar cortex. This process pertains to the initial formation of a structure from unspecified parts. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function. http://purl.obolibrary.org/obo/CL_0002380 oospore http://purl.obolibrary.org/obo/CL_0000605 fungal asexual spore An asexual spore formed by Oomycetes; formed upon fertilization of an oosphere. http://purl.obolibrary.org/obo/GO_0021699 cerebellar cortex maturation http://purl.obolibrary.org/obo/GO_0071695 anatomical structure maturation A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar cortex to attain its fully functional state. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function. http://purl.obolibrary.org/obo/CL_0002381 uninucleate conidium http://purl.obolibrary.org/obo/CL_0000599 conidium A conidium that has only one nucleus. http://purl.obolibrary.org/obo/GO_0021701 cerebellar Golgi cell differentiation http://purl.obolibrary.org/obo/GO_0097154 GABAergic neuron differentiation The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar Golgi cell. Differentiation includes the processes involved in commitment of a neuroblast to a Golgi cell fate. A cerebellar Golgi cell is an inhibitory GABAergic interneuron found in the cerebellar cortex. http://purl.obolibrary.org/obo/CL_0002382 multinucleate conidium http://purl.obolibrary.org/obo/CL_0000599 conidium A conidium that has more than one nucleus. http://purl.obolibrary.org/obo/CL_0002383 conidium of conidiophore head http://purl.obolibrary.org/obo/CL_0002381 uninucleate conidium A uninucleate spore formed on specialized cells or projections, sterigma, of a conidiophore head. http://purl.obolibrary.org/obo/GO_0021702 cerebellar Purkinje cell differentiation http://purl.obolibrary.org/obo/GO_0097154 GABAergic neuron differentiation The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar Purkinje cell. Differentiation includes the processes involved in commitment of a neuroblast to a Purkinje cell fate. A Purkinje cell is an inhibitory GABAergic neuron found in the cerebellar cortex that projects to the deep cerebellar nuclei and brain stem. http://purl.obolibrary.org/obo/CL_0002384 uninucleate macroconidium http://purl.obolibrary.org/obo/CL_0002381 uninucleate conidium A macroconidium that has only one nucleus. http://purl.obolibrary.org/obo/CL_0002385 blastoconidium http://purl.obolibrary.org/obo/CL_0000606 macroconidium An oblong or round asexual spore formed from conidial chains. http://purl.obolibrary.org/obo/GO_0021703 locus ceruleus development http://purl.obolibrary.org/obo/GO_0048857 neural nucleus development The process whose specific outcome is the progression of the locus ceruleus over time, from its formation to the mature structure. The locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic. http://purl.obolibrary.org/obo/CL_0002386 multinucleate macroconidium http://purl.obolibrary.org/obo/CL_0002382 multinucleate conidium A macroconidium that has more than one nucleus. http://purl.obolibrary.org/obo/CL_0002387 arthroconidium http://purl.obolibrary.org/obo/CL_0000606 macroconidium Cylindrical spore formed by development and compartmentation of hyphae; the hyphae are often supporting blastoconidiophores. http://purl.obolibrary.org/obo/GO_0021704 locus ceruleus morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structure of the locus ceruleus is generated and organized. In mice, the locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic. http://purl.obolibrary.org/obo/CL_0002388 multinucleate arthroconidium http://purl.obolibrary.org/obo/CL_0002387 arthroconidium An arthroconidium that has more than one nucleus. http://purl.obolibrary.org/obo/GO_0021705 locus ceruleus formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process that gives rise to the locus ceruleus. This process pertains to the initial formation of a structure from unspecified parts. In mice, the locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic. http://purl.obolibrary.org/obo/CL_0002389 uninucleate arthroconidium http://purl.obolibrary.org/obo/CL_0002387 arthroconidium An arthroconidium that has only one nucleus. http://purl.obolibrary.org/obo/CL_0002390 uninucleate blastconidium http://purl.obolibrary.org/obo/CL_0002385 blastoconidium A blastoconidium that has only one nucleus. http://purl.obolibrary.org/obo/GO_0021706 locus ceruleus maturation http://purl.obolibrary.org/obo/GO_0071695 anatomical structure maturation A developmental process, independent of morphogenetic (shape) change, that is required for the locus ceruleus to attain its fully functional state. The locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic. http://purl.obolibrary.org/obo/CL_0002391 multinucleate blastoconidium http://purl.obolibrary.org/obo/CL_0002386 multinucleate macroconidium A blastoconidium that has more than one nucleus. http://purl.obolibrary.org/obo/CL_0002393 intermediate monocyte http://purl.obolibrary.org/obo/CL_0000576 monocyte A monocyte that has characteristics of both patrolling and inflammatory monocytes. http://purl.obolibrary.org/obo/GO_0021707 cerebellar granule cell differentiation http://purl.obolibrary.org/obo/GO_0021953 central nervous system neuron differentiation The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar granule cell. Differentiation includes the processes involved in commitment of a neuroblast to a granule cell fate. A granule cell is a glutamatergic interneuron found in the cerebellar cortex. http://purl.obolibrary.org/obo/CL_0002394 CD141-positive myeloid dendritic cell http://purl.obolibrary.org/obo/CL_0000784 plasmacytoid dendritic cell A myeloid dendritic cell found in the blood, lymph nodes, tonsil, bone marrow, and spleen that is CD141-positive (BDCA-3), XCR1-positive, and Clec9A-positive. This cell-type can cross-present antigen to CD8-positive T cells and can produce inteferon-beta. http://purl.obolibrary.org/obo/GO_0021708 Lugaro cell differentiation http://purl.obolibrary.org/obo/GO_0097154 GABAergic neuron differentiation The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature Lugaro cell. Differentiation includes the processes involved in commitment of a neuroblast to a Lugaro cell fate. A Lugaro cell is an inhibitory GABAergic interneuron found in the cerebellar cortex. http://purl.obolibrary.org/obo/CL_0002395 Gr1-high classical monocyte http://purl.obolibrary.org/obo/CL_0001022 CD115-positive monocyte A resident monocyte that is Gr-1 high, CD43-negative, CX3CR1-negative, CD115-positive, and B220-negative. http://purl.obolibrary.org/obo/CL_0002396 CD14-low, CD16-positive monocyte http://purl.obolibrary.org/obo/CL_0001054 CD14-positive monocyte A patrolling monocyte that is CD14-low and CD16-positive. http://purl.obolibrary.org/obo/GO_0021710 cerebellar stellate cell differentiation http://purl.obolibrary.org/obo/GO_0097154 GABAergic neuron differentiation The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar stellate cell. Differentiation includes the processes involved in commitment of a neuroblast to a cerebellar stellate cell fate. A cerebellar stellate cell is an inhibitory GABAergic interneuron found in the cerebellar cortex. http://purl.obolibrary.org/obo/CL_0002397 CD14-positive, CD16-positive monocyte http://purl.obolibrary.org/obo/CL_0001054 CD14-positive monocyte A CD14-positive monocyte that is also CD16-positive and CCR2-negative. http://purl.obolibrary.org/obo/GO_0021718 superior olivary nucleus development http://purl.obolibrary.org/obo/GO_0048857 neural nucleus development The process whose specific outcome is the progression of the superior olivary nucleus over time, from its formation to the mature structure. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound. http://purl.obolibrary.org/obo/CL_0002398 Gr1-positive, CD43-positive monocyte http://purl.obolibrary.org/obo/CL_0002393 intermediate monocyte An intermediate monocyte that is Gr1-positive, CD43-positive. http://purl.obolibrary.org/obo/CL_0002399 CD1c-positive myeloid dendritic cell http://purl.obolibrary.org/obo/CL_0000782 myeloid dendritic cell A myeloid dendritic cell that is CD1c-positive. http://purl.obolibrary.org/obo/GO_0021719 superior olivary nucleus morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structure of the superior olivary nucleus is generated and organized. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound. http://purl.obolibrary.org/obo/CL_0002400 fraction B/C precursor B cell http://purl.obolibrary.org/obo/CL_0000817 precursor B cell A precursor B cell that is AA4-positive, IgM-negative, CD19-positive, CD43-positive and HSA-positive. http://purl.obolibrary.org/obo/CL_0002401 mature dendritic epithelial T cell precursor http://purl.obolibrary.org/obo/CL_0002404 fetal thymocyte A thymocyte that has a T cell receptor consisting of a gamma chain that has as part a Vgamma3 segment, and a delta chain. This cell type is CD4-negative, CD8-negative and CD24-negative. This cell-type is found in the fetal thymus with highest numbers occurring at E17-E18. http://purl.obolibrary.org/obo/GO_0021720 superior olivary nucleus formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process that gives rise to the superior olivary nucleus. This process pertains to the initial formation of a structure from unspecified parts. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound. http://purl.obolibrary.org/obo/CL_0002402 Peyer's patch B cell http://purl.obolibrary.org/obo/CL_0009014 Peyer's patch lymphocyte A resting mature B cell within the Peyer's patch that is CD19-positive, B220-positive, IgM-positive, AA4-negative, CD23-positive, CD43-negative, and CD5-negative. http://purl.obolibrary.org/obo/CL_0002403 mature Vgamma2-positive fetal thymocyte http://purl.obolibrary.org/obo/CL_0002404 fetal thymocyte A thymocyte that has a T cell receptor consisting of a gamma chain containing Vgamma2 segment, and a delta chain. This cell type is CD4-negative, CD8-negative and CD24-negative. This cell-type is found in the fetal thymus. http://purl.obolibrary.org/obo/GO_0021722 superior olivary nucleus maturation http://purl.obolibrary.org/obo/GO_0071695 anatomical structure maturation A developmental process, independent of morphogenetic (shape) change, that is required for the superior olivary nucleus to attain its fully functional state. The superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound. http://purl.obolibrary.org/obo/CL_0002404 fetal thymocyte http://purl.obolibrary.org/obo/CL_0000893 thymocyte A thymocyte found in the fetal thymus. http://purl.obolibrary.org/obo/CL_0002405 gamma-delta thymocyte http://purl.obolibrary.org/obo/CL_0002489 double negative thymocyte A post-natal thymocyte expressing components of the gamma-delta T cell receptor. This cell type is always double-negative (i.e. CD4-negative, CD8-negative). http://purl.obolibrary.org/obo/GO_0021732 midbrain-hindbrain boundary maturation http://purl.obolibrary.org/obo/GO_0071695 anatomical structure maturation A developmental process, independent of morphogenetic (shape) change, that is required for the midbrain-hindbrain boundary to attain its fully functional state. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate. http://purl.obolibrary.org/obo/CL_0002406 immature Vgamma2-positive thymocyte http://purl.obolibrary.org/obo/CL_0002405 gamma-delta thymocyte A double negative post-natal thymocyte that has a T cell receptor consisting of a gamma chain containing a Vgamma2 segment, and a delta chain. This cell type is CD4-negative, CD8-negative and CD24-positive. http://purl.obolibrary.org/obo/CL_0002407 mature Vgamma2-positive thymocyte http://purl.obolibrary.org/obo/CL_0002405 gamma-delta thymocyte A thymocyte that has a T cell receptor consisting of a gamma chain containing Vgamma2 segment, and a delta chain. This cell type is CD4-negative, CD8-negative and CD24-negative. http://purl.obolibrary.org/obo/GO_0021743 hypoglossal nucleus development http://purl.obolibrary.org/obo/GO_0048857 neural nucleus development The process whose specific outcome is the progression of the hypoglossal nucleus over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/CL_0002408 immature Vgamma2-negative thymocyte http://purl.obolibrary.org/obo/CL_0002405 gamma-delta thymocyte A double negative post-natal thymocyte that has a T cell receptor consisting of a gamma chain that does not contain a Vgamma2 segment, and a delta chain. This cell type is CD4-negative, CD8-negative and CD24-positive. http://purl.obolibrary.org/obo/GO_0021747 cochlear nucleus development http://purl.obolibrary.org/obo/GO_0048857 neural nucleus development The process whose specific outcome is the progression of the cochlear nucleus over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/CL_0002409 mature Vgamma2-negative thymocyte http://purl.obolibrary.org/obo/CL_0002405 gamma-delta thymocyte A thymocyte that has a T cell receptor consisting of a gamma chain that does not contain the Vgamma2 segment, and a delta chain. This cell type is CD4-negative, CD8-negative and CD24-negative. http://purl.obolibrary.org/obo/GO_0021748 dorsal cochlear nucleus development http://purl.obolibrary.org/obo/GO_0021747 cochlear nucleus development The process whose specific outcome is the progression of the dorsal cochlear nucleus over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0021749 ventral cochlear nucleus development http://purl.obolibrary.org/obo/GO_0021747 cochlear nucleus development The process whose specific outcome is the progression of the ventral cochlear nucleus over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/CL_0002410 pancreatic stellate cell http://purl.obolibrary.org/obo/CL_0002574 stromal cell of pancreas A cell that is found in the periacinar space of the exocrine pancreas and in perivascular and periductal regions of the pancreas, and has long cytoplasmic processes that encircle the base of the acinus. Expresses several intermediate filament proteins including vimentin and nestin. Shares many of the characteristics of hepatatic stellate cells, but not stellate cells of the central nervous system. Upon activation, this cell type undergoes morphological and gene expression changes that make the cell suggestive of being a type of myofibroblast. http://purl.obolibrary.org/obo/GO_0021750 vestibular nucleus development http://purl.obolibrary.org/obo/GO_0048857 neural nucleus development The process whose specific outcome is the progression of the vestibular nucleus over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0021751 salivary nucleus development http://purl.obolibrary.org/obo/GO_0048857 neural nucleus development The process whose specific outcome is the progression of a salivary nucleus over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/CL_0002411 Vgamma1.1-positive, Vdelta6.3-negative thymocyte http://purl.obolibrary.org/obo/CL_0002405 gamma-delta thymocyte A gamma-delta receptor that expresses Vgamma1.1 but does not express Vdelta6.3 chains in the T-cell receptor. http://purl.obolibrary.org/obo/GO_0021753 superior salivary nucleus development http://purl.obolibrary.org/obo/GO_0021751 salivary nucleus development The process whose specific outcome is the progression of the superior salivary nucleus over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/CL_0002412 Vgamma1.1-positive, Vdelta6.3-positive thymocyte http://purl.obolibrary.org/obo/CL_0002405 gamma-delta thymocyte A gamma-delta receptor that expresses Vgamma1.1-Vdelta6.3 chains in the T-cell receptor. http://purl.obolibrary.org/obo/CL_0002413 mature Vgamma1.1-positive, Vdelta6.3-negative thymocyte http://purl.obolibrary.org/obo/CL_0002411 Vgamma1.1-positive, Vdelta6.3-negative thymocyte A Vgamma1.1-positive, Vdelta6.3-negative thymocyte that is CD24-negative. http://purl.obolibrary.org/obo/GO_0021754 facial nucleus development http://purl.obolibrary.org/obo/GO_0048857 neural nucleus development The process whose specific outcome is the progression of the facial nucleus over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/CL_0002414 immature Vgamma1.1-positive, Vdelta6.3-negative thymocyte http://purl.obolibrary.org/obo/CL_0002411 Vgamma1.1-positive, Vdelta6.3-negative thymocyte A Vgamma1.1-positive, Vdelta6.3-negative thymocyte that is CD24-positive. http://purl.obolibrary.org/obo/GO_0021755 eurydendroid cell differentiation http://purl.obolibrary.org/obo/GO_0021953 central nervous system neuron differentiation The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature eurydendroid cell. Differentiation includes the processes involved in commitment of a neuroblast to a eurydendroid cell fate. A eurydendroid cell is an efferent neuron found in the cerebellar cortex of teleosts. http://purl.obolibrary.org/obo/CL_0002415 immature Vgamma1.1-positive, Vdelta6.3-positive thymocyte http://purl.obolibrary.org/obo/CL_0002412 Vgamma1.1-positive, Vdelta6.3-positive thymocyte A Vgamma1.1-positive, Vdelta6.3-positive thymocyte that is CD24-positive. http://purl.obolibrary.org/obo/GO_0021756 striatum development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the striatum over time from its initial formation until its mature state. The striatum is a region of the forebrain consisting of the caudate nucleus, putamen and fundus striati. http://purl.obolibrary.org/obo/CL_0002416 mature Vgamma1.1-positive, Vdelta6.3-positive thymocyte http://purl.obolibrary.org/obo/CL_0002412 Vgamma1.1-positive, Vdelta6.3-positive thymocyte A Vgamma1.1-positive, Vdelta6.3-positive thymocyte that is CD24-negative. http://purl.obolibrary.org/obo/GO_0021757 caudate nucleus development http://purl.obolibrary.org/obo/GO_0048857 neural nucleus development The progression of the caudate nucleus over time from its initial formation until its mature state. The caudate nucleus is the C-shaped structures of the striatum containing input neurons involved with control of voluntary movement in the brain. http://purl.obolibrary.org/obo/CL_0002417 primitive erythroid lineage cell http://purl.obolibrary.org/obo/CL_0000764 erythroid lineage cell An immature or mature cell of the first erythroid lineage to arise during embryonic development. http://purl.obolibrary.org/obo/CL_0002418 hemangioblast http://purl.obolibrary.org/obo/CL_0000222 mesodermal cell A pluripotent cell in the yolk sac that can give rise to mesenchymal cells including erythrocytes and endothelial cells. http://purl.obolibrary.org/obo/GO_0021758 putamen development http://purl.obolibrary.org/obo/GO_0048857 neural nucleus development The progression of the putamen over time from its initial formation until its mature state. The putamen is the lens-shaped basal ganglion involved with control of voluntary movement in the brain. http://purl.obolibrary.org/obo/CL_0002419 mature T cell http://purl.obolibrary.org/obo/CL_0000084 T cell A T cell that expresses a T cell receptor complex and has completed T cell selection. http://purl.obolibrary.org/obo/GO_0021759 globus pallidus development http://purl.obolibrary.org/obo/GO_0048857 neural nucleus development The progression of the globus pallidus over time from its initial formation until its mature state. The globus pallidus is one of the basal ganglia involved with control of voluntary movement in the brain. http://purl.obolibrary.org/obo/CL_0002420 immature T cell http://purl.obolibrary.org/obo/CL_0000084 T cell A T cell that has not completed T cell selection. http://purl.obolibrary.org/obo/GO_0021761 limbic system development http://purl.obolibrary.org/obo/GO_0048731 system development The progression of the limbic system over time from its initial formation until its mature state. The limbic system is a collection of structures in the brain involved in emotion, motivation and emotional aspects of memory. http://purl.obolibrary.org/obo/CL_0002421 nucleated reticulocyte http://purl.obolibrary.org/obo/CL_0002242 nucleate cell A reticulocyte that retains the nucleus and other organelles. Found in birds, fish, amphibians and reptiles. http://purl.obolibrary.org/obo/CL_0002422 enucleated reticulocyte http://purl.obolibrary.org/obo/CL_0000558 reticulocyte A reticulocyte lacking a nucleus and showing a basophilic reticulum under vital staining due to the presence of ribosomes. http://purl.obolibrary.org/obo/GO_0021762 substantia nigra development http://purl.obolibrary.org/obo/GO_0048857 neural nucleus development The progression of the substantia nigra over time from its initial formation until its mature state. The substantia nigra is the layer of gray substance that separates the posterior parts of the cerebral peduncles (tegmentum mesencephali) from the anterior parts; it normally includes a posterior compact part with many pigmented cells (pars compacta) and an anterior reticular part whose cells contain little pigment (pars reticularis). http://purl.obolibrary.org/obo/CL_0002423 DN2a thymocyte http://purl.obolibrary.org/obo/CL_0000806 DN2 thymocyte A DN2 thymocyte that is Kit-hi. http://purl.obolibrary.org/obo/CL_0002424 DN2b thymocyte http://purl.obolibrary.org/obo/CL_0000806 DN2 thymocyte A DN2 thymocyte that is Kit-low. http://purl.obolibrary.org/obo/GO_0021763 subthalamic nucleus development http://purl.obolibrary.org/obo/GO_0048857 neural nucleus development The progression of the subthalamic nucleus over time from its initial formation until its mature state. The subthalamic nucleus is the lens-shaped nucleus located in the ventral part of the subthalamus on the inner aspect of the internal capsule that is concerned with the integration of somatic motor function. http://purl.obolibrary.org/obo/CL_0002425 early T lineage precursor http://purl.obolibrary.org/obo/CL_0000827 pro-T cell A pro-T cell that is lin-negative, CD25-negative, CD127-negative, CD44-positive and kit-positive. http://purl.obolibrary.org/obo/CL_0002426 CD11b-positive, CD27-positive natural killer cell, mouse http://purl.obolibrary.org/obo/CL_0002438 NK1.1-positive natural killer cell, mouse A mature natural killer cell that is CD11b-positive and CD27-positive. http://purl.obolibrary.org/obo/GO_0021764 amygdala development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the amygdala over time from its initial formation until its mature state. The amygdala is an almond-shaped set of neurons in the medial temporal lobe of the brain that play a key role in processing emotions such as fear and pleasure. http://purl.obolibrary.org/obo/CL_0002427 resting double-positive thymocyte http://purl.obolibrary.org/obo/CL_0000809 double-positive, alpha-beta thymocyte A double-positive, alpha-beta thymocyte that is small and not proliferating. http://purl.obolibrary.org/obo/GO_0021766 hippocampus development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the hippocampus over time from its initial formation until its mature state. http://purl.obolibrary.org/obo/CL_0002428 double-positive blast http://purl.obolibrary.org/obo/CL_0000809 double-positive, alpha-beta thymocyte A double-positive thymocyte that is large (i.e. has a high forward scatter signal in flow cytometry) and is actively proliferating. http://purl.obolibrary.org/obo/GO_0021767 mammillary body development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the mammillary body over time from its initial formation until its mature state. The mammillary body is a protrusion at the posterior end of the hypothalamus that contains hypothalamic nuclei. http://purl.obolibrary.org/obo/CL_0002429 CD69-positive double-positive thymocyte http://purl.obolibrary.org/obo/CL_0000809 double-positive, alpha-beta thymocyte A double-positive thymocyte that is CD69-positive and has begun positive selection. http://purl.obolibrary.org/obo/GO_0021768 nucleus accumbens development http://purl.obolibrary.org/obo/GO_0048857 neural nucleus development The progression of the nucleus accumbens over time from its initial formation until its mature state. The nucleus accumbens is a collection of pleomorphic cells in the caudal part of the anterior horn of the lateral ventricle, in the region of the olfactory tubercle, lying between the head of the caudate nucleus and the anterior perforated substance. It is part of the ventral striatum, a composite structure considered part of the basal ganglia. http://purl.obolibrary.org/obo/CL_0002430 CD4-intermediate, CD8-positive double-positive thymocyte http://purl.obolibrary.org/obo/CL_0000809 double-positive, alpha-beta thymocyte A double-positive thymocyte that is undergoing positive selection, has high expression of the alpha-beta T cell receptor, is CD69-positive, and is in the process of down regulating the CD4 co-receptor. http://purl.obolibrary.org/obo/CL_0002431 CD4-positive, CD8-intermediate double-positive thymocyte http://purl.obolibrary.org/obo/CL_0000809 double-positive, alpha-beta thymocyte A double-positive thymocyte that is undergoing positive selection, has high expression of the alpha-beta T cell receptor, is CD69-positive, and is in the process of down regulating the CD8 co-receptor. http://purl.obolibrary.org/obo/GO_0021771 lateral geniculate nucleus development http://purl.obolibrary.org/obo/GO_0048857 neural nucleus development The progression of the lateral geniculate nucleus over time from its initial formation until its mature state. The lateral geniculate nucleus is the primary processor of visual information received from the retina. http://purl.obolibrary.org/obo/CL_0002432 CD24-positive, CD4 single-positive thymocyte http://purl.obolibrary.org/obo/CL_0000810 CD4-positive, alpha-beta thymocyte A CD4-positive, CD8-negative thymocyte that is CD24-positive and expresses high levels of the alpha-beta T cell receptor. http://purl.obolibrary.org/obo/GO_0021772 olfactory bulb development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the olfactory bulb over time from its initial formation until its mature state. The olfactory bulb coordinates neuronal signaling involved in the perception of smell. It receives input from the sensory neurons and outputs to the olfactory cortex. http://purl.obolibrary.org/obo/CL_0002433 CD69-positive, CD4-positive single-positive thymocyte http://purl.obolibrary.org/obo/CL_0000810 CD4-positive, alpha-beta thymocyte A CD4-positive, CD8-negative thymocyte that expresses high levels of the alpha-beta T cell receptor and is CD69-positive. http://purl.obolibrary.org/obo/CL_0002434 CD24-positive, CD8 single-positive thymocyte http://purl.obolibrary.org/obo/CL_0000811 CD8-positive, alpha-beta thymocyte A CD8-positive, CD4-negative thymocyte that is CD24-positive and expresses high levels of the alpha-beta T cell receptor. http://purl.obolibrary.org/obo/GO_0021773 striatal medium spiny neuron differentiation http://purl.obolibrary.org/obo/GO_0097154 GABAergic neuron differentiation The process in which a relatively unspecialized cell acquires specialized features of a medium spiny neuron residing in the striatum. http://purl.obolibrary.org/obo/CL_0002435 CD69-positive, CD8-positive single-positive thymocyte http://purl.obolibrary.org/obo/CL_0000811 CD8-positive, alpha-beta thymocyte A CD8-positive, CD4-negative thymocyte that expresses high levels of the alpha-beta T cell receptor and is CD69-positive. http://purl.obolibrary.org/obo/GO_0021783 preganglionic parasympathetic fiber development http://purl.obolibrary.org/obo/GO_0048731 system development The process whose specific outcome is the progression of a preganglionic parasympathetic fiber over time, from its formation to the mature structure. A preganglionic parasympathetic fiber is a cholinergic axonal fiber projecting from the CNS to a parasympathetic ganglion. http://purl.obolibrary.org/obo/CL_0002436 mature CD4 single-positive thymocyte http://purl.obolibrary.org/obo/CL_0000624 CD4-positive, alpha-beta T cell A mature CD4-positive, CD8-negative alpha-beta T cell found in the thymus that is CD24-low and has high expression of the T cell receptor. http://purl.obolibrary.org/obo/GO_0021794 thalamus development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process in which the thalamus changes over time, from its initial formation to its mature state. http://purl.obolibrary.org/obo/CL_0002437 mature CD8 single-positive thymocyte http://purl.obolibrary.org/obo/CL_0000625 CD8-positive, alpha-beta T cell A mature CD8-positive, CD4-negative alpha-beta T cell found in the thymus that is CD24-low and has high expression of the T cell receptor. http://purl.obolibrary.org/obo/GO_0021795 cerebral cortex cell migration http://purl.obolibrary.org/obo/GO_0022029 telencephalon cell migration The orderly movement of cells from one site to another in the cerebral cortex. http://purl.obolibrary.org/obo/CL_0002438 NK1.1-positive natural killer cell, mouse http://purl.obolibrary.org/obo/CL_0000824 mature natural killer cell A mature NK cell that is NK1.1-positive. http://purl.obolibrary.org/obo/GO_0021799 cerebral cortex radially oriented cell migration http://purl.obolibrary.org/obo/GO_0021795 cerebral cortex cell migration The migration of cells in the developing cerebral cortex in which cells move from the ventricular and/or subventricular zone toward the surface of the brain. http://purl.obolibrary.org/obo/CL_0002439 NKGA2-positive natural killer cell, mouse http://purl.obolibrary.org/obo/CL_0002438 NK1.1-positive natural killer cell, mouse A NK1.1-positive T cell that is NKGA2-positive. http://purl.obolibrary.org/obo/GO_0021801 cerebral cortex radial glia-guided migration http://purl.obolibrary.org/obo/GO_0022030 telencephalon glial cell migration The radial migration of neuronal or glial precursor cells along radial glial cells during the development of the cerebral cortex. http://purl.obolibrary.org/obo/CL_0002440 Ly49D-positive natural killer cell, mouse http://purl.obolibrary.org/obo/CL_0002438 NK1.1-positive natural killer cell, mouse A NK1.1-positive T cell that is Ly49D-positive. http://purl.obolibrary.org/obo/GO_0021814 cell motility involved in cerebral cortex radial glia guided migration http://purl.obolibrary.org/obo/GO_0048870 cell motility The movement of a cell along the process of a radial glial cell involved in cerebral cortex glial-mediated radial migration. http://purl.obolibrary.org/obo/CL_0002441 CD94-positive natural killer cell, mouse http://purl.obolibrary.org/obo/CL_0002438 NK1.1-positive natural killer cell, mouse A NK1.1-positive T cell that is CD94-positive. http://purl.obolibrary.org/obo/GO_0021815 modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration http://purl.obolibrary.org/obo/GO_0000226 microtubule cytoskeleton organization Rearrangements of the microtubule cytoskeleton that contribute to the movement of cells along radial glial cells as a component of the process of cerebral cortex glial-mediated radial migration. http://purl.obolibrary.org/obo/CL_0002442 CD94-negative, Ly49CI-negative natural killer cell, mouse http://purl.obolibrary.org/obo/CL_0000623 natural killer cell A NK1.1-positive T cell that is CD94-negative and Ly49Cl-negative. http://purl.obolibrary.org/obo/CL_0002443 Ly49CI-positive natural killer cell, mouse http://purl.obolibrary.org/obo/CL_0002438 NK1.1-positive natural killer cell, mouse A NK1.1-positive T cell that is Ly49Cl-positive. http://purl.obolibrary.org/obo/GO_0021819 layer formation in cerebral cortex http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The detachment of cells from radial glial fibers at the appropriate time when they cease to migrate and form distinct layer in the cerebral cortex. http://purl.obolibrary.org/obo/CL_0002444 Ly49H-positive natural killer cell, mouse http://purl.obolibrary.org/obo/CL_0002438 NK1.1-positive natural killer cell, mouse A NK1.1-positive T cell that is Ly49H-positive. http://purl.obolibrary.org/obo/GO_0021822 negative regulation of cell motility involved in cerebral cortex radial glia guided migration http://purl.obolibrary.org/obo/GO_1903976 negative regulation of glial cell migration The intracellular signaling pathway that results in the cessation of cell movement involved in lamination of the cerebral cortex. http://purl.obolibrary.org/obo/CL_0002445 Ly49D-negative natural killer cell, mouse http://purl.obolibrary.org/obo/CL_0002438 NK1.1-positive natural killer cell, mouse A NK1.1-positive T cell that is Ly49D-negative. http://purl.obolibrary.org/obo/GO_0021826 substrate-independent telencephalic tangential migration http://purl.obolibrary.org/obo/GO_0022029 telencephalon cell migration The process where neuronal precursors migrate tangentially in the telencephalon, primarily guided by interactions that do not require cell-cell contact. http://purl.obolibrary.org/obo/CL_0002446 Ly49CI-negative natural killer cell, mouse http://purl.obolibrary.org/obo/CL_0002438 NK1.1-positive natural killer cell, mouse A NK1.1-positive T cell that is Ly49Cl-negative. http://purl.obolibrary.org/obo/GO_0021830 interneuron migration from the subpallium to the cortex http://purl.obolibrary.org/obo/GO_0021843 substrate-independent telencephalic tangential interneuron migration The directed movement of interneurons from the subpallium to the cortex during forebrain development. http://purl.obolibrary.org/obo/CL_0002447 CD94-negative natural killer cell, mouse http://purl.obolibrary.org/obo/CL_0002438 NK1.1-positive natural killer cell, mouse A NK1.1-positive T cell that is CD94-negative. http://purl.obolibrary.org/obo/CL_0002448 Ly49H-negative natural killer cell, mouse http://purl.obolibrary.org/obo/CL_0002438 NK1.1-positive natural killer cell, mouse A NK1.1-positive T cell that is Ly49H-negative. http://purl.obolibrary.org/obo/GO_0021843 substrate-independent telencephalic tangential interneuron migration http://purl.obolibrary.org/obo/GO_0021826 substrate-independent telencephalic tangential migration The directional movement of tangentially migrating interneurons that are not guided by attaching to extracellular substrates. http://purl.obolibrary.org/obo/CL_0002449 CD94-positive Ly49CI-positive natural killer cell, mouse http://purl.obolibrary.org/obo/CL_0002443 Ly49CI-positive natural killer cell, mouse A NK1.1-positive T cell that is CD94-positive and Ly49Cl-positive. http://purl.obolibrary.org/obo/GO_0021846 cell proliferation in forebrain http://purl.obolibrary.org/obo/GO_0061351 neural precursor cell proliferation The creation of greater cell numbers in the forebrain due to cell division of progenitor cells. http://purl.obolibrary.org/obo/CL_0002450 tether cell http://purl.obolibrary.org/obo/CL_0002374 ear hair cell A specialized hair cell that has an elongated kinocilium upon which an otolith accretes. The tether cell then anchors the otolith in place. http://purl.obolibrary.org/obo/GO_0021848 neuroblast division in subpallium http://purl.obolibrary.org/obo/GO_0055057 neuroblast division The division of neuroblasts in the subpallium area of the forebrain. The interneuron precursors that these cells give rise to include GABAergic interneurons and will migrate tangentially. http://purl.obolibrary.org/obo/CL_0002451 mammary stem cell http://purl.obolibrary.org/obo/CL_0000048 multi fate stem cell A multi-fate stem cell that is the source of cells for growth of the mammary gland during puberty and gestation. This cell type gives rise to both the luminal and myoepithelial cell types of the gland, and have been shown to have the ability to regenerate the entire organ in mice. This cell type also plays an important role in carcinogenesis of the breast. This cell type is Lin-, CD24-positive, CD29-hi. http://purl.obolibrary.org/obo/GO_0021852 pyramidal neuron migration to cerebral cortex http://purl.obolibrary.org/obo/GO_0140650 radial glia-guided pyramidal neuron migration The migration of a pyramidal neuron precursor from the ventricular zone to the correct layer of the cerebral cortex. http://purl.obolibrary.org/obo/GO_0021853 cerebral cortex GABAergic interneuron migration http://purl.obolibrary.org/obo/GO_1904936 interneuron migration The migration of GABAergic interneuron precursors from the subpallium to the cerebral cortex. http://purl.obolibrary.org/obo/CL_0002453 oligodendrocyte precursor cell http://purl.obolibrary.org/obo/CL_0011026 progenitor cell A proliferative and migratory glial progenitor cell that derives from a neural stem cell and resides within the central nervous system. It possesses the capacity to differentiate into a committed oligodendrocyte progenitor (COP) through a well-defined series of maturation steps, ultimately giving rise to a myelinating oligodendrocyte (MOL). In mice and humans, it is characterized by the expression of specific molecular markers, including Pdgfra, Cspg4 (also known as NG2) and Olig2. http://purl.obolibrary.org/obo/GO_0021854 hypothalamus development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the hypothalamus region of the forebrain, from its initial formation to its mature state. http://purl.obolibrary.org/obo/CL_0002454 CD4-negative, CD8-alpha-negative, CD11b-positive dendritic cell http://purl.obolibrary.org/obo/CL_0002465 CD11b-positive dendritic cell CD4-negative, CD8-alpha-negative, CD11b-positive dendritic cell is a conventional dendritic cell that is CD11b-positive, CD4-negative, CD8-alpha-negative and is CD205-positive. http://purl.obolibrary.org/obo/GO_0021859 pyramidal neuron differentiation http://purl.obolibrary.org/obo/GO_0021953 central nervous system neuron differentiation The process in which a neuroblast or one of its progeny commits to a pyramidal neuron fate, migrates from the ventricular zone to the appropriate layer in the cortex and develops into a mature neuron. http://purl.obolibrary.org/obo/GO_0021860 pyramidal neuron development http://purl.obolibrary.org/obo/GO_0021884 forebrain neuron development The progression of a pyramidal neuron from its initial formation to its mature state. http://purl.obolibrary.org/obo/CL_0002455 CD8-alpha-negative plasmacytoid dendritic cell http://purl.obolibrary.org/obo/CL_0000989 CD11c-low plasmacytoid dendritic cell A CD11c-low plasmacytoid dendritic cell that is CD8-alpha-negative and CD4-positive. http://purl.obolibrary.org/obo/GO_0021861 forebrain radial glial cell differentiation http://purl.obolibrary.org/obo/GO_0060019 radial glial cell differentiation The process in which neuroepithelial cells of the neural tube give rise to radial glial cells, specialized bipotential progenitors cells of the forebrain. Differentiation includes the processes involved in commitment of a cell to a specific fate. http://purl.obolibrary.org/obo/CL_0002456 CD8-alpha-positive plasmacytoid dendritic cell http://purl.obolibrary.org/obo/CL_0000989 CD11c-low plasmacytoid dendritic cell A CD11c-low plasmacytoid dendritic cell that is CD8-alpha-positive and CD4-positive. http://purl.obolibrary.org/obo/GO_0021863 forebrain neuroblast differentiation http://purl.obolibrary.org/obo/GO_0014016 neuroblast differentiation The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of basal progenitor cells, neuroblasts that lose their contacts with the ventricular surface. Differentiation includes the processes involved in commitment of a cell to a specific fate. http://purl.obolibrary.org/obo/GO_0021870 Cajal-Retzius cell differentiation http://purl.obolibrary.org/obo/GO_0021895 cerebral cortex neuron differentiation The process in which a neuroblast acquires specialized structural and/or functional features of a Cajal-Retzius cell, one of a transient population of pioneering neurons in the cerebral cortex. These cells are slender bipolar cells of the developing marginal zone. One feature of these cells in mammals is that they express the Reelin gene. http://purl.obolibrary.org/obo/CL_0002457 epidermal Langerhans cell http://purl.obolibrary.org/obo/CL_0002465 CD11b-positive dendritic cell A Langerhans cell that is in the epidermis and is CD45-positive, MHCII-positive, and CD11b-positive. http://purl.obolibrary.org/obo/GO_0021872 forebrain generation of neurons http://purl.obolibrary.org/obo/GO_0048699 generation of neurons The process in which nerve cells are generated in the forebrain. This includes the production of neuroblasts from and their differentiation into neurons. http://purl.obolibrary.org/obo/CL_0002458 langerin-positive dermal dendritic cell http://purl.obolibrary.org/obo/CL_0002461 CD103-positive dendritic cell A dermal dendritic cell that is langerin-positive and CD103-positive. http://purl.obolibrary.org/obo/GO_0021879 forebrain neuron differentiation http://purl.obolibrary.org/obo/GO_0021953 central nervous system neuron differentiation The process in which a relatively unspecialized cell acquires specialized features of a neuron that will reside in the forebrain. http://purl.obolibrary.org/obo/CL_0002459 langerin-negative dermal dendritic cell http://purl.obolibrary.org/obo/CL_0001006 dermal dendritic cell A dermal dendritic cell that is langerin-negative, CD103-negative, and CD11b-positive. http://purl.obolibrary.org/obo/GO_0021884 forebrain neuron development http://purl.obolibrary.org/obo/GO_0021954 central nervous system neuron development The process whose specific outcome is the progression of a neuron that resides in the forebrain, from its initial commitment to its fate, to the fully functional differentiated cell. http://purl.obolibrary.org/obo/CL_0002460 CD8-alpha-negative thymic conventional dendritic cell http://purl.obolibrary.org/obo/CL_0000941 thymic conventional dendritic cell A conventional thymic dendritic cell that is CD8-alpha-negative. http://purl.obolibrary.org/obo/CL_0002461 CD103-positive dendritic cell http://purl.obolibrary.org/obo/CL_0000990 conventional dendritic cell A conventional dendritic cell that is CD103-positive. This cell type is usually found in non-lymphoid tissue. http://purl.obolibrary.org/obo/GO_0021885 forebrain cell migration http://purl.obolibrary.org/obo/GO_0016477 cell migration The orderly movement of a cell from one site to another at least one of which is located in the forebrain. http://purl.obolibrary.org/obo/CL_0002462 adipose dendritic cell http://purl.obolibrary.org/obo/CL_0002320 connective tissue cell A F4/80-negative dendritic cell located in adipose tissue. http://purl.obolibrary.org/obo/GO_0021889 olfactory bulb interneuron differentiation http://purl.obolibrary.org/obo/GO_0021879 forebrain neuron differentiation The process in which a neuroblast acquires specialized features of an interneuron residing in the olfactory bulb. http://purl.obolibrary.org/obo/CL_0002463 SIRPa-positive adipose dendritic cell http://purl.obolibrary.org/obo/CL_0002462 adipose dendritic cell An adipose dendritic cell that is SIRPa-positive. http://purl.obolibrary.org/obo/GO_0021891 olfactory bulb interneuron development http://purl.obolibrary.org/obo/GO_0021884 forebrain neuron development The process whose specific outcome is the progression of an interneuron residing in the olfactory bulb, from its initial commitment, to the fully functional differentiated cell. http://purl.obolibrary.org/obo/CL_0002464 SIRPa-negative adipose dendritic cell http://purl.obolibrary.org/obo/CL_0002462 adipose dendritic cell An adipose dendritic cell that is SIRPa-negative. http://purl.obolibrary.org/obo/GO_0021892 cerebral cortex GABAergic interneuron differentiation http://purl.obolibrary.org/obo/GO_0097154 GABAergic neuron differentiation The process in which a relatively unspecialized cell acquires specialized features of a GABAergic interneuron residing in the cerebral cortex. http://purl.obolibrary.org/obo/CL_0002465 CD11b-positive dendritic cell http://purl.obolibrary.org/obo/CL_0000990 conventional dendritic cell A conventional dendritic cell that expresses CD11b (ITGAM). http://purl.obolibrary.org/obo/CL_0002466 small intestine serosal dendritic cell http://purl.obolibrary.org/obo/CL_0002465 CD11b-positive dendritic cell A CD11b-positive dendritic cell located in the serosal portion of the small intestine epithelium. This cell type is CD45-positive, MHC-II-positive, CD11c-low, CD103-negative. http://purl.obolibrary.org/obo/GO_0021894 cerebral cortex GABAergic interneuron development http://purl.obolibrary.org/obo/GO_0021884 forebrain neuron development The process whose specific outcome is the progression of a cerebral cortex GABAergic interneuron over time, from initial commitment to its fate, to the fully functional differentiated cell. http://purl.obolibrary.org/obo/CL_0002467 Gr1-high myeloid suppressor cell http://purl.obolibrary.org/obo/CL_0000889 myeloid suppressor cell A myeloid suppressor cell that is Gr1-high and CD11c-negative. http://purl.obolibrary.org/obo/GO_0021895 cerebral cortex neuron differentiation http://purl.obolibrary.org/obo/GO_0021879 forebrain neuron differentiation The process in which a relatively unspecialized cell acquires specialized features of a neuron residing in the cerebral cortex. http://purl.obolibrary.org/obo/CL_0002468 Gr1-low myeloid suppressor cell http://purl.obolibrary.org/obo/CL_0000889 myeloid suppressor cell A myeloid suppressor cell that is Gr1-low and CD11c-positive. http://purl.obolibrary.org/obo/GO_0021896 forebrain astrocyte differentiation http://purl.obolibrary.org/obo/GO_0048708 astrocyte differentiation The process in which a relatively unspecialized cell acquires the specialized features of an astrocyte residing in the forebrain. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function. http://purl.obolibrary.org/obo/CL_0002469 MHC-II-negative classical monocyte http://purl.obolibrary.org/obo/CL_0002395 Gr1-high classical monocyte Gr1-high monocyte that lacks MHC-II receptor complex. http://purl.obolibrary.org/obo/GO_0021897 forebrain astrocyte development http://purl.obolibrary.org/obo/GO_0014002 astrocyte development The process aimed at the progression of an astrocyte that resides in the forebrain, from initial commitment of the cell to its fate, to the fully functional differentiated cell. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function. http://purl.obolibrary.org/obo/CL_0002470 MHC-II-positive classical monocyte http://purl.obolibrary.org/obo/CL_0002395 Gr1-high classical monocyte Gr1-high monocyte that has a MHC-II receptor complex. http://purl.obolibrary.org/obo/CL_0002471 MHC-II-negative non-classical monocyte http://purl.obolibrary.org/obo/CL_0002058 Gr1-low non-classical monocyte Gr1-low non-classical monocyte that lacks expression of a MHC-II complex. http://purl.obolibrary.org/obo/GO_0021903 rostrocaudal neural tube patterning http://purl.obolibrary.org/obo/GO_0009952 anterior/posterior pattern specification The process in which the neural tube is divided into specific regions along the rostrocaudal axis. http://purl.obolibrary.org/obo/CL_0002472 MHC-II-low non-classical monocyte http://purl.obolibrary.org/obo/CL_0002058 Gr1-low non-classical monocyte Gr1-low non-classical monocyte that has low to intermediate expression of the MHC-II complex. http://purl.obolibrary.org/obo/GO_0021905 forebrain-midbrain boundary formation http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the creation of the forebrain-midbrain boundary. http://purl.obolibrary.org/obo/CL_0002473 MHC-II-high non-classical monocyte http://purl.obolibrary.org/obo/CL_0002058 Gr1-low non-classical monocyte Gr1-low non-classical monocyte that has high surface expression of a MHC-II complex. http://purl.obolibrary.org/obo/GO_0021906 hindbrain-spinal cord boundary formation http://purl.obolibrary.org/obo/GO_0048859 formation of anatomical boundary The process whose specific outcome is the formation of the hindbrain-spinal cord boundary. http://purl.obolibrary.org/obo/CL_0002474 lymphoid MHC-II-negative classical monocyte http://purl.obolibrary.org/obo/CL_0002469 MHC-II-negative classical monocyte A MHC-II-negative classical monocyte located in lymphoid tissue that is F4/80-positive, CD11c-negative, and CD11b-high. http://purl.obolibrary.org/obo/GO_0021921 regulation of cell proliferation in dorsal spinal cord http://purl.obolibrary.org/obo/GO_2000177 regulation of neural precursor cell proliferation The process that modulates the frequency, rate or extent of cell proliferation in the dorsal spinal cord. http://purl.obolibrary.org/obo/CL_0002475 lymphoid MHC-II-negative non-classical monocyte http://purl.obolibrary.org/obo/CL_0002471 MHC-II-negative non-classical monocyte A MHC-II-negative classical monocyte located in lymphoid tissue that is F4/80-positive, CD11c-intermediate, and CD11b-high. http://purl.obolibrary.org/obo/GO_0021952 central nervous system projection neuron axonogenesis http://purl.obolibrary.org/obo/GO_0021955 central nervous system neuron axonogenesis Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body towards target cells in a different central nervous system region. http://purl.obolibrary.org/obo/CL_0002476 bone marrow macrophage http://purl.obolibrary.org/obo/CL_0010004 mononuclear cell of bone marrow A tissue-resident macrophage located in the bone marrow. This cell type is B220-negative, CD3e-negative, Ly-6C-negative, CD115-positive, F4/80-positive. http://purl.obolibrary.org/obo/GO_0021953 central nervous system neuron differentiation http://purl.obolibrary.org/obo/GO_0030182 neuron differentiation The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the central nervous system. http://purl.obolibrary.org/obo/CL_0002477 adipose macrophage http://purl.obolibrary.org/obo/CL_0000864 tissue-resident macrophage A macrophage located in adipose tissue that is CD45-positive, CD11c-positive, and SIRPa-positive. http://purl.obolibrary.org/obo/GO_0021954 central nervous system neuron development http://purl.obolibrary.org/obo/GO_0048666 neuron development The process whose specific outcome is the progression of a neuron whose cell body is located in the central nervous system, from initial commitment of the cell to a neuronal fate, to the fully functional differentiated neuron. http://purl.obolibrary.org/obo/CL_0002478 F4/80-negative adipose macrophage http://purl.obolibrary.org/obo/CL_0002477 adipose macrophage An adipose macrophage that does not express F4/80but is MHC-II-positive. This cell type exhibits autofluorescence under typical flow cyometry conditions. http://purl.obolibrary.org/obo/GO_0021955 central nervous system neuron axonogenesis http://purl.obolibrary.org/obo/GO_0007409 axonogenesis Generation of a long process from a neuron whose cell body resides in the central nervous system. The process carries efferent (outgoing) action potentials from the cell body towards target cells. http://purl.obolibrary.org/obo/CL_0002479 F4/80-positive adipose macrophage http://purl.obolibrary.org/obo/CL_0002477 adipose macrophage An adipose macrophage that does not express MHC-II but is F4/80-positive. http://purl.obolibrary.org/obo/CL_0002480 nasal mucosa goblet cell http://purl.obolibrary.org/obo/CL_0002631 epithelial cell of upper respiratory tract A goblet cell located in the nasal epithelium. http://purl.obolibrary.org/obo/GO_0021957 corticospinal tract morphogenesis http://purl.obolibrary.org/obo/GO_0021952 central nervous system projection neuron axonogenesis Generation of a long process of a pyramidal cell, that carries efferent (outgoing) action potentials from the cell body in cerebral cortex layer V towards target cells in the gray matter of the spinal cord. This axonal process is a member of those that make up the corticospinal tract. http://purl.obolibrary.org/obo/CL_0002481 peritubular myoid cell http://purl.obolibrary.org/obo/CL_0002625 seminiferous tubule epithelial cell The flattened smooth myoepithelial cells of mesodermal origin that lie just outside the basal lamina of the seminiferous tubule. http://purl.obolibrary.org/obo/GO_0021961 posterior commissure morphogenesis http://purl.obolibrary.org/obo/GO_0021952 central nervous system projection neuron axonogenesis Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the midbrain towards target cells in the diencephalon. http://purl.obolibrary.org/obo/CL_0002482 dermal melanocyte http://purl.obolibrary.org/obo/CL_1000458 melanocyte of skin A melanocyte that produces pigment in the dermis. http://purl.obolibrary.org/obo/CL_0002483 hair follicle melanocyte http://purl.obolibrary.org/obo/CL_2000000 epidermal melanocyte A melanocyte that produces pigment within the hair follicle. http://purl.obolibrary.org/obo/GO_0021964 rubrospinal tract morphogenesis http://purl.obolibrary.org/obo/GO_0021952 central nervous system projection neuron axonogenesis Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the red nucleus of the midbrain towards target cells in the spinal cord. http://purl.obolibrary.org/obo/CL_0002484 epithelial melanocyte http://purl.obolibrary.org/obo/CL_0000148 melanocyte A melanocyte that produces pigment in the epithelium. http://purl.obolibrary.org/obo/GO_0021982 pineal gland development http://purl.obolibrary.org/obo/GO_0048732 gland development The progression of the pineal gland over time from its initial formation until its mature state. The pineal gland is an endocrine gland that secretes melatonin and is involved in circadian rhythms. http://purl.obolibrary.org/obo/CL_0002485 retinal melanocyte http://purl.obolibrary.org/obo/CL_0009004 retinal cell A melanocyte of the retina. This cell type is distinct from pigmented retinal epithelium. http://purl.obolibrary.org/obo/GO_0021983 pituitary gland development http://purl.obolibrary.org/obo/GO_0048732 gland development The progression of the pituitary gland over time from its initial formation until its mature state. The pituitary gland is an endocrine gland that secretes hormones that regulate many other glands. http://purl.obolibrary.org/obo/CL_0002486 strial intermediate cell http://purl.obolibrary.org/obo/CL_0002491 auditory epithelial cell A melanocyte located between the epithelial marginal cell layer and the mesodermal basal cell layer within the intrastrial space; the predominant cellular component of the electrogenic machinery that generates an endocochlear potential (80-100 mV) . http://purl.obolibrary.org/obo/GO_0021984 adenohypophysis development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the adenohypophysis over time from its initial formation until its mature state. The adenohypophysis is the anterior part of the pituitary. It secretes a variety of hormones and its function is regulated by the hypothalamus. http://purl.obolibrary.org/obo/CL_0002487 cutaneous/subcutaneous mechanoreceptor cell http://purl.obolibrary.org/obo/CL_0000199 mechanoreceptor cell A neuronal receptor that respond to mechanical pressure or distortion in the skin. http://purl.obolibrary.org/obo/CL_0002488 trophoblast giant cell http://purl.obolibrary.org/obo/CL_0000351 trophoblast cell A trophoblast cell that has a large volume of cytoplasm, is polyploid and is usually mononuclear but is also occasionally multi-nucleate. This cell type is important in establishing maternal physiology and remodeling of the vasculature of the placenta. http://purl.obolibrary.org/obo/GO_0021985 neurohypophysis development http://purl.obolibrary.org/obo/GO_0048732 gland development The progression of the neurohypophysis over time from its initial formation until its mature state. The neurohypophysis is the part of the pituitary gland that secretes hormones involved in blood pressure regulation. http://purl.obolibrary.org/obo/CL_0002489 double negative thymocyte http://purl.obolibrary.org/obo/CL_0000893 thymocyte A thymocyte that lacks expression of CD4 and CD8. http://purl.obolibrary.org/obo/GO_0021987 cerebral cortex development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the cerebral cortex over time from its initial formation until its mature state. The cerebral cortex is the outer layered region of the telencephalon. http://purl.obolibrary.org/obo/CL_0002490 organ of Corti supporting cell http://purl.obolibrary.org/obo/CL_0002315 supporting cell of cochlea A supporting cell of the organ of Corti. http://purl.obolibrary.org/obo/GO_0021988 olfactory lobe development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the olfactory lobe over time from its initial formation until its mature state. The olfactory lobe is the area of the brain that process the neural inputs for the sense of smell. http://purl.obolibrary.org/obo/CL_0002491 auditory epithelial cell http://purl.obolibrary.org/obo/CL_0000098 sensory epithelial cell A specialized cell involved in auditory sensory perception. http://purl.obolibrary.org/obo/GO_0021989 olfactory cortex development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the olfactory cortex over time from its initial formation until its mature state. The olfactory cortex is involved in the perception of smell. It receives input from the olfactory bulb and is responsible for the identification of odors. http://purl.obolibrary.org/obo/CL_0002492 strial marginal cell http://purl.obolibrary.org/obo/CL_0002491 auditory epithelial cell A polarized columnar cell that covesr the lateral surface of the cochlear duct, secretes potassium ions and forms a continuous sheet in contact with the endolymph; marginal cells form extensive interdigitations with the basal and intermediate cells in the normal adult stria. http://purl.obolibrary.org/obo/GO_0021990 neural plate formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The formation of the flat, thickened layer of ectodermal cells known as the neural plate. The underlying dorsal mesoderm signals the ectodermal cells above it to elongate into columnar neural plate cells. The neural plate subsequently develops into the neural tube, which gives rise to the central nervous system. http://purl.obolibrary.org/obo/CL_0002493 strial basal cell http://purl.obolibrary.org/obo/CL_0002491 auditory epithelial cell A polarized cell that is juxtaposed to fibrocytes in the underlying spiral ligament. This cell type secretes potassium ions derived from fibrocytes through gap junctions. http://purl.obolibrary.org/obo/CL_0002494 cardiocyte http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell A cell located in the heart, including both muscle and non muscle cells. http://purl.obolibrary.org/obo/GO_0021999 neural plate anterior/posterior regionalization http://purl.obolibrary.org/obo/GO_0060897 neural plate regionalization The process that regulates the coordinated growth and differentiation that establishes the non-random anterior-posterior spatial arrangement of the neural plate. http://purl.obolibrary.org/obo/CL_0002495 fetal cardiomyocyte http://purl.obolibrary.org/obo/CL_0000746 cardiac muscle cell A fetal and neonatal heart cell that undergoes proliferation and is not yet terminally differentiated into a binucleate or a multinucleate cardiac myocyte. http://purl.obolibrary.org/obo/GO_0022006 zona limitans intrathalamica formation http://purl.obolibrary.org/obo/GO_0048859 formation of anatomical boundary The formation of the narrow stripe of cells that lies between the prospective dorsal and ventral thalami. This boundary contains signals that pattern the prethalamic and thalamic territories of the future mid-diencephalon. http://purl.obolibrary.org/obo/CL_0002496 intraepithelial lymphocyte http://purl.obolibrary.org/obo/CL_0002419 mature T cell A tissue-resident lymphocyte located within the epithelial layer of mucosal tissues, particularly within the gastrointestinal, respiratory, and reproductive tracts. Characterised by permanent residency, this cell typically expresses CD103 (integrin alpha-E), which binds to E-cadherin on epithelial cells, enabling epithelial retention in both mice and humans. Phenotypically, IEL displays an activated, antigen-experienced state characterised by the constitutive expression of cytotoxic molecules (granzyme B, perforin) and innate-like receptors (such as NKG2D), enabling rapid, localised surveillance and immediate response to epithelial stress. http://purl.obolibrary.org/obo/GO_0022008 neurogenesis http://purl.obolibrary.org/obo/GO_0030154 cell differentiation Generation of cells within the nervous system. http://purl.obolibrary.org/obo/GO_0022009 central nervous system vasculogenesis http://purl.obolibrary.org/obo/GO_0001570 vasculogenesis The differentiation of endothelial cells from progenitor cells during blood vessel development, and the de novo formation of blood vessels and tubes in the central nervous system. The capillary endothelial cells in the brain are specialized to form the blood-brain barrier. http://purl.obolibrary.org/obo/CL_0002497 primary trophoblast giant cell http://purl.obolibrary.org/obo/CL_0002488 trophoblast giant cell A trophoblast giant cell derived from the mural trophectoderm. http://purl.obolibrary.org/obo/GO_0022010 central nervous system myelination http://purl.obolibrary.org/obo/GO_0042552 myelination The process in which neuronal axons and dendrites become coated with a segmented lipid-rich sheath (myelin) to enable faster and more energetically efficient conduction of electrical impulses. The sheath is formed by the cell membranes of oligodendrocytes in the central nervous system. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier. http://purl.obolibrary.org/obo/CL_0002498 secondary trophoblast giant cell http://purl.obolibrary.org/obo/CL_0002488 trophoblast giant cell A trophoblast giant cell that is derived from ectoplacental cone and, later in gestation, the spongiotrophoblast. http://purl.obolibrary.org/obo/GO_0022011 myelination in peripheral nervous system http://purl.obolibrary.org/obo/GO_0042552 myelination The process in which neuronal axons and dendrites become coated with a segmented lipid-rich sheath (myelin) to enable faster and more energetically efficient conduction of electrical impulses. The sheath is formed by the cell membranes of Schwann cells in the peripheral nervous system. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier. http://purl.obolibrary.org/obo/CL_0002499 spongiotrophoblast cell http://purl.obolibrary.org/obo/CL_0000351 trophoblast cell A trophoblast cell that arises in the junctional zone (basal plate) of the placenta. http://purl.obolibrary.org/obo/CL_0002500 P enteroendocrine cell http://purl.obolibrary.org/obo/CL_0002268 P/D1 enteroendocrine cell A P/D1 enteroendocrine cell that is Grimelius positive and stores bombesin-like polypeptide. http://purl.obolibrary.org/obo/GO_0022012 subpallium cell proliferation in forebrain http://purl.obolibrary.org/obo/GO_0021846 cell proliferation in forebrain The multiplication or reproduction of subpallium cells in the forebrain, resulting in the expansion of a cell population. http://purl.obolibrary.org/obo/CL_0002501 type D1 enteroendocrine cell http://purl.obolibrary.org/obo/CL_0002268 P/D1 enteroendocrine cell A P/D1 enteroendocrine cell that is argyrophilic and stores vasoactive intestinal polypeptide. http://purl.obolibrary.org/obo/GO_0022029 telencephalon cell migration http://purl.obolibrary.org/obo/GO_0021885 forebrain cell migration The orderly movement of a cell from one site to another at least one of which is located in the telencephalon. http://purl.obolibrary.org/obo/CL_0002502 type M enteroendocrine cell http://purl.obolibrary.org/obo/CL_0009006 enteroendocrine cell of small intestine An enteroendocrine cell of the small intestine that secretes motilin. http://purl.obolibrary.org/obo/GO_0022030 telencephalon glial cell migration http://purl.obolibrary.org/obo/GO_0008347 glial cell migration The orderly movement of glial cells through the telencephalon. http://purl.obolibrary.org/obo/CL_0002503 adventitial cell http://purl.obolibrary.org/obo/CL_0002320 connective tissue cell A cell of the adventitial layer of ductal structures such as the uterer, defent duct, biliary duct, etc http://purl.obolibrary.org/obo/GO_0022031 telencephalon astrocyte cell migration http://purl.obolibrary.org/obo/GO_0043615 astrocyte cell migration The orderly movement of an astrocyte cell through the telencephalon. http://purl.obolibrary.org/obo/CL_0002504 enteric smooth muscle cell http://purl.obolibrary.org/obo/CL_0000192 smooth muscle cell A smooth muscle cell of the intestine. http://purl.obolibrary.org/obo/GO_0022032 telencephalon oligodendrocyte cell migration http://purl.obolibrary.org/obo/GO_0022030 telencephalon glial cell migration The multiplication or reproduction of telencephalon oligodendrocyte cells, resulting in the expansion of a cell population. http://purl.obolibrary.org/obo/CL_0002505 liver CD103-negative dendritic cell http://purl.obolibrary.org/obo/CL_0002454 CD4-negative, CD8-alpha-negative, CD11b-positive dendritic cell A CD11b-positive dendritic cell that is CD11b-high, CD45-positive, MHC-II-positive and CD103-negative. http://purl.obolibrary.org/obo/GO_0022033 telencephalon microglial cell migration http://purl.obolibrary.org/obo/GO_0022030 telencephalon glial cell migration The orderly movement of microglial cells through the telencephalon. http://purl.obolibrary.org/obo/CL_0002506 liver CD103-positive dendritic cell http://purl.obolibrary.org/obo/CL_0002461 CD103-positive dendritic cell A CD11b-positive dendritic cell that is CD11b-low, CD45-positive, MHC-II-high and CD103-positive that is located in the liver. http://purl.obolibrary.org/obo/GO_0022035 rhombomere cell migration http://purl.obolibrary.org/obo/GO_0021535 cell migration in hindbrain The movement of a cell within a rhombomere. This process is known to occur as an early step in the generation of anatomical structure from a rhombomere. http://purl.obolibrary.org/obo/CL_0002507 langerin-positive lymph node dendritic cell http://purl.obolibrary.org/obo/CL_0000990 conventional dendritic cell A dermal dendritic cell isolated from skin draining lymph nodes that is langerin-positive, MHC-II-positive, and CD4-negative and CD8a-negative. http://purl.obolibrary.org/obo/GO_0022037 metencephalon development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the metencephalon over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/CL_0002508 langerin-negative, CD103-negative lymph node dendritic cell http://purl.obolibrary.org/obo/CL_0000990 conventional dendritic cell A dermal dendritic cell isolated from skin draining lymph nodes that is langerin-negative, MHC-II-positive, and CD4-negative and CD8a-negative. http://purl.obolibrary.org/obo/GO_0022038 corpus callosum development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the corpus callosum over time, from its formation to the mature structure. The corpus callosum is a thick bundle of nerve fibers comprising a commissural plate connecting the two cerebral hemispheres. It consists of contralateral axon projections that provide communication between the right and left cerebral hemispheres. http://purl.obolibrary.org/obo/CL_0002509 CD103-positive, langerin-positive lymph node dendritic cell http://purl.obolibrary.org/obo/CL_0002507 langerin-positive lymph node dendritic cell A langerin-positive lymph node dendritic cell that is CD103-positive and CD11b-low. http://purl.obolibrary.org/obo/CL_0002510 CD103-negative, langerin-positive lymph node dendritic cell http://purl.obolibrary.org/obo/CL_0002507 langerin-positive lymph node dendritic cell A langerin-positive lymph node dendritic cell that is CD103-negative and CD11b-high. http://purl.obolibrary.org/obo/GO_0022407 regulation of cell-cell adhesion http://purl.obolibrary.org/obo/GO_0030155 regulation of cell adhesion Any process that modulates the frequency, rate or extent of attachment of a cell to another cell. http://purl.obolibrary.org/obo/CL_0002511 CD11b-low, CD103-negative, langerin-negative lymph node dendritic cell http://purl.obolibrary.org/obo/CL_0002508 langerin-negative, CD103-negative lymph node dendritic cell A langerin-negative lymph node dendritic cell that is CD103-negative and CD11b-low. http://purl.obolibrary.org/obo/GO_0022408 negative regulation of cell-cell adhesion http://purl.obolibrary.org/obo/GO_0022407 regulation of cell-cell adhesion Any process that stops, prevents or reduces the rate or extent of cell adhesion to another cell. http://purl.obolibrary.org/obo/CL_0002512 CD11b-high, CD103-negative, langerin-negative lymph node dendritic cell http://purl.obolibrary.org/obo/CL_0002508 langerin-negative, CD103-negative lymph node dendritic cell A langerin-negative lymph node dendritic cell that is CD103-negative and CD11b-high. http://purl.obolibrary.org/obo/GO_0022409 positive regulation of cell-cell adhesion http://purl.obolibrary.org/obo/GO_0045785 positive regulation of cell adhesion Any process that activates or increases the rate or extent of cell adhesion to another cell. http://purl.obolibrary.org/obo/CL_0002513 Vgamma5-positive CD8-alpha alpha positive gamma-delta intraepithelial T cell http://purl.obolibrary.org/obo/CL_0000802 CD8-alpha alpha positive, gamma-delta intraepithelial T cell A CD8-alpha alpha positive gamma-delta intraepithelial T cell that expresses a TCR encoded in part by the Vgamma5 gene segment. http://purl.obolibrary.org/obo/GO_0022605 mammalian oogenesis stage http://purl.obolibrary.org/obo/GO_0048609 multicellular organismal reproductive process A reproductive process that is a step in the formation and maturation of an ovum or female gamete from a primordial female germ cell. http://purl.obolibrary.org/obo/CL_0002514 Vgamma5-negative CD8-alpha alpha positive gamma-delta intraepithelial T cell http://purl.obolibrary.org/obo/CL_0000802 CD8-alpha alpha positive, gamma-delta intraepithelial T cell A CD8-alpha alpha positive gamma-delta intraepithelial T cell that does not express a TCR partially encoded by the Vgamma5 gene segment. http://purl.obolibrary.org/obo/GO_0022613 ribonucleoprotein complex biogenesis http://purl.obolibrary.org/obo/GO_0044085 cellular component biogenesis A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a complex containing RNA and proteins. Includes the biosynthesis of the constituent RNA and protein molecules, and those macromolecular modifications that are involved in synthesis or assembly of the ribonucleoprotein complex. http://purl.obolibrary.org/obo/CL_0002515 interrenal norepinephrine type cell http://purl.obolibrary.org/obo/CL_0002516 interrenal chromaffin cell An interrenal chromaffin cell found in teleosts that contain heterogeneous vesicles with electron-dense granules located asymmetrically within the vesicular membrane. http://purl.obolibrary.org/obo/CL_0002516 interrenal chromaffin cell http://purl.obolibrary.org/obo/CL_0000166 chromaffin cell A chromaffin cell interspersed among the interrenal epithelial layer of the anterior kidney of teloest fish. http://purl.obolibrary.org/obo/GO_0022835 transmitter-gated channel activity http://purl.obolibrary.org/obo/GO_0022834 ligand-gated channel activity Enables the transmembrane transfer of a solute by a channel that opens when a specific neurotransmitter has been bound by the channel complex or one of its constituent parts. http://purl.obolibrary.org/obo/CL_0002517 interrenal epinephrin secreting cell http://purl.obolibrary.org/obo/CL_0002516 interrenal chromaffin cell An interrenal chromaffin cell found in teleosts that contain small, homogeneous electron-lucent granules that are separated from the vesicular membrane by a visible halo. http://purl.obolibrary.org/obo/GO_0022836 gated channel activity http://purl.obolibrary.org/obo/GO_0015267 channel activity Enables the transmembrane transfer of a solute by a channel that opens in response to a specific stimulus. http://purl.obolibrary.org/obo/GO_0022849 glutamate-gated calcium ion channel activity http://purl.obolibrary.org/obo/GO_0099604 ligand-gated calcium channel activity Enables the transmembrane transfer of a calcium ion by a channel that opens when glutamate has been bound by the channel complex or one of its constituent parts. http://purl.obolibrary.org/obo/CL_0002518 kidney epithelial cell http://purl.obolibrary.org/obo/CL_1000497 kidney cell An epithelial cell of the kidney. http://purl.obolibrary.org/obo/CL_0002519 interrenal epithelial cell http://purl.obolibrary.org/obo/CL_0002518 kidney epithelial cell An interrenal epithelial kidney cell is an epithelial cell found in the anterior kidney of teleosts fish. This cell type is arranged in layers around the posterior cardinal vein and contains many mitochondria with tubulovesicular cristae. Interrenal chromaffin cells are interspersed among the tissue layer created by this cell type. http://purl.obolibrary.org/obo/GO_0022898 regulation of transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0065009 regulation of molecular function Any process that modulates the frequency, rate or extent of transmembrane transporter activity. http://purl.obolibrary.org/obo/GO_0023019 signal transduction involved in regulation of gene expression http://purl.obolibrary.org/obo/GO_0007165 signal transduction Any process that modulates the frequency, rate or extent of gene expression as a consequence of a process in which a signal is released and/or conveyed from one location to another. http://purl.obolibrary.org/obo/CL_0002520 nephrocyte http://purl.obolibrary.org/obo/CL_0002522 renal filtration cell An insect excretory cell that regulates hemolymph composition by filtration and filtrate endocytosis. http://purl.obolibrary.org/obo/GO_0023023 MHC protein complex binding http://purl.obolibrary.org/obo/GO_0044877 protein-containing complex binding Binding to a major histocompatibility complex. http://purl.obolibrary.org/obo/CL_0002521 subcutaneous adipocyte http://purl.obolibrary.org/obo/CL_0000136 adipocyte An adipocyte that is part of subcutaneous adipose tissue. http://purl.obolibrary.org/obo/GO_0023026 MHC class II protein complex binding http://purl.obolibrary.org/obo/GO_0023023 MHC protein complex binding Binding to a class II major histocompatibility complex. http://purl.obolibrary.org/obo/CL_0002522 renal filtration cell http://purl.obolibrary.org/obo/CL_0000424 excretory cell A renal filtration cell is a specialized cell of the renal system that filter fluids by charge, size or both. http://purl.obolibrary.org/obo/GO_0023029 MHC class Ib protein binding http://purl.obolibrary.org/obo/GO_0042287 MHC protein binding Binding to a major histocompatibility complex class Ib molecules. http://purl.obolibrary.org/obo/CL_0002523 mesonephric podocyte http://purl.obolibrary.org/obo/CL_0000653 podocyte A specialized epithelial cell that contains "feet" that interdigitate with the "feet" of other glomerular epithelial cells in the mesonephros. http://purl.obolibrary.org/obo/GO_0023052 signaling http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process The entirety of a process in which information is transmitted within a biological system. This process begins with an active signal and ends when a cellular response has been triggered. http://purl.obolibrary.org/obo/CL_0002524 disseminated nephrocyte http://purl.obolibrary.org/obo/CL_0002520 nephrocyte A disseminated nephrocyte is a nephrocyte that filters hemolymph and is found at scattered locations in the fat body or other tissues. http://purl.obolibrary.org/obo/GO_0023061 signal release http://purl.obolibrary.org/obo/GO_0032940 secretion by cell The process in which a signal is secreted or discharged into the extracellular medium from a cellular source. http://purl.obolibrary.org/obo/CL_0002525 metanephric podocyte http://purl.obolibrary.org/obo/CL_0000653 podocyte A specialized epithelial cell that contains "feet" that interdigitate with the "feet" of other glomerular epithelial cells in the metanephros. http://purl.obolibrary.org/obo/GO_0030016 myofibril http://purl.obolibrary.org/obo/GO_0043292 contractile muscle fiber The contractile element of skeletal and cardiac muscle; a long, highly organized bundle of actin, myosin, and other proteins that contracts by a sliding filament mechanism. http://purl.obolibrary.org/obo/CL_0002526 CD14-positive dermal dendritic cell http://purl.obolibrary.org/obo/CL_0001006 dermal dendritic cell A dermal dendritic cell that is CD1a-negative and CD14-positive. http://purl.obolibrary.org/obo/GO_0030029 actin filament-based process http://purl.obolibrary.org/obo/GO_0009987 cellular process Any cellular process that depends upon or alters the actin cytoskeleton, that part of the cytoskeleton comprising actin filaments and their associated proteins. http://purl.obolibrary.org/obo/CL_0002527 immature CD14-positive dermal dendritic cell http://purl.obolibrary.org/obo/CL_0002526 CD14-positive dermal dendritic cell An immature CD14-positive dermal dendritic cell is CD80-low, CD86-low, and MHCII-low. http://purl.obolibrary.org/obo/GO_0030030 cell projection organization http://purl.obolibrary.org/obo/GO_0016043 cellular component organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon. http://purl.obolibrary.org/obo/CL_0002528 mature CD14-positive dermal dendritic cell http://purl.obolibrary.org/obo/CL_0002526 CD14-positive dermal dendritic cell A mature CD14-positive dermal dendritic cell is CD80-high, CD86-high, MHCII-high and is CD83-positive. http://purl.obolibrary.org/obo/GO_0030033 microvillus assembly http://purl.obolibrary.org/obo/GO_0120031 plasma membrane bounded cell projection assembly Formation of a microvillus, a thin cylindrical membrane-covered projection on the surface of a cell. http://purl.obolibrary.org/obo/CL_0002529 CD1a-positive dermal dendritic cell http://purl.obolibrary.org/obo/CL_0001006 dermal dendritic cell A dermal dendritic cell that is CD1a-positive and CD14-negative. http://purl.obolibrary.org/obo/GO_0030048 actin filament-based movement http://purl.obolibrary.org/obo/GO_0030029 actin filament-based process Movement of organelles or other particles along actin filaments, or sliding of actin filaments past each other, mediated by motor proteins. http://purl.obolibrary.org/obo/CL_0002530 immature CD1a-positive dermal dendritic cell http://purl.obolibrary.org/obo/CL_0002529 CD1a-positive dermal dendritic cell An immature CD1a-positive dermal dendritic cell is CD80-low, CD86-low, and MHCII-low. http://purl.obolibrary.org/obo/GO_0030050 vesicle transport along actin filament http://purl.obolibrary.org/obo/GO_0099518 vesicle cytoskeletal trafficking Movement of a vesicle along an actin filament, mediated by motor proteins. http://purl.obolibrary.org/obo/CL_0002531 mature CD1a-positive dermal dendritic cell http://purl.obolibrary.org/obo/CL_0002529 CD1a-positive dermal dendritic cell A mature CD1a-positive dermal dendritic cell is CD80-high, CD83-positive, CD86-high, and MHCII-high. http://purl.obolibrary.org/obo/GO_0030057 desmosome http://purl.obolibrary.org/obo/GO_0005911 cell-cell junction A cell-cell junction in which: on the cytoplasmic surface of each interacting plasma membrane is a dense plaque composed of a mixture of intracellular anchor proteins; a bundle of keratin intermediate filaments is attached to the surface of each plaque; transmembrane adhesion proteins of the cadherin family bind to the plaques and interact through their extracellular domains to hold the adjacent membranes together by a Ca2+-dependent mechanism. http://purl.obolibrary.org/obo/CL_0002532 CD16-positive myeloid dendritic cell http://purl.obolibrary.org/obo/CL_0000782 myeloid dendritic cell A myeloid dendritic cell found in the blood that is CD16-positive. http://purl.obolibrary.org/obo/CL_0002533 immature CD16-positive myeloid dendritic cell http://purl.obolibrary.org/obo/CL_0002532 CD16-positive myeloid dendritic cell An immature CD16-positive myeloid dendritic cell is CD80-low, CD86-low, and MHCII-low. http://purl.obolibrary.org/obo/GO_0030070 insulin processing http://purl.obolibrary.org/obo/GO_1901142 insulin metabolic process The formation of mature insulin by proteolysis of the precursor preproinsulin. The signal sequence is first cleaved from preproinsulin to form proinsulin; proinsulin is then cleaved to release the C peptide, leaving the A and B chains of mature insulin linked by disulfide bridges. http://purl.obolibrary.org/obo/CL_0002534 mature CD16-positive myeloid dendritic cell http://purl.obolibrary.org/obo/CL_0002532 CD16-positive myeloid dendritic cell A mature CD16-positive myeloid dendritic cell is CD80-high, CD83-positive, CD86-high, and MHCII-high. http://purl.obolibrary.org/obo/CL_0002535 epithelial cell of cervix http://purl.obolibrary.org/obo/CL_0002149 epithelial cell of uterus An epithelial cell of the cervix. http://purl.obolibrary.org/obo/GO_0030072 peptide hormone secretion http://purl.obolibrary.org/obo/GO_0046879 hormone secretion The regulated release of a peptide hormone from a cell. http://purl.obolibrary.org/obo/CL_0002536 epithelial cell of amnion http://purl.obolibrary.org/obo/CL_0000066 epithelial cell An epithelial cell that is part of the amnion. http://purl.obolibrary.org/obo/CL_0002537 amnion mesenchymal stem cell http://purl.obolibrary.org/obo/CL_0000134 mesenchymal stem cell A mesenchymal stem cell of the amnion membrane. http://purl.obolibrary.org/obo/GO_0030073 insulin secretion http://purl.obolibrary.org/obo/GO_0030072 peptide hormone secretion The regulated release of proinsulin from secretory granules accompanied by cleavage of proinsulin to form mature insulin. In vertebrates, insulin is secreted from B granules in the B cells of the vertebrate pancreas and from insulin-producing cells in insects. http://purl.obolibrary.org/obo/CL_0002538 intrahepatic cholangiocyte http://purl.obolibrary.org/obo/CL_1000488 cholangiocyte An epithelial cell of the intrahepatic portion of the bile duct. These cells are flattened or cuboidal in shape, and have a small nuclear-to-cytoplasmic ratio relative to large/extrahepatic cholangiocytes. http://purl.obolibrary.org/obo/GO_0030100 regulation of endocytosis http://purl.obolibrary.org/obo/GO_0060627 regulation of vesicle-mediated transport Any process that modulates the frequency, rate or extent of endocytosis. http://purl.obolibrary.org/obo/CL_0002539 aortic smooth muscle cell http://purl.obolibrary.org/obo/CL_0019018 blood vessel smooth muscle cell A smooth muscle cell of the aorta. http://purl.obolibrary.org/obo/GO_0030133 transport vesicle http://purl.obolibrary.org/obo/GO_0031410 cytoplasmic vesicle Any of the vesicles of the constitutive secretory pathway, which carry cargo from the endoplasmic reticulum to the Golgi, between Golgi cisternae, from the Golgi to the ER (retrograde transport) or to destinations within or outside the cell. http://purl.obolibrary.org/obo/CL_0002540 mesenchymal stem cell of the bone marrow http://purl.obolibrary.org/obo/CL_0002092 bone marrow cell A mesenchymal stem cell that is part of the bone marrow. http://purl.obolibrary.org/obo/GO_0030136 clathrin-coated vesicle http://purl.obolibrary.org/obo/GO_0030135 coated vesicle A vesicle with a coat formed of clathrin connected to the membrane via one of the clathrin adaptor complexes. http://purl.obolibrary.org/obo/CL_0002541 chorionic membrane mesenchymal stem cell http://purl.obolibrary.org/obo/CL_0000134 mesenchymal stem cell A mesenchymal stem cell of the chorionic membrane. http://purl.obolibrary.org/obo/GO_0030150 protein import into mitochondrial matrix http://purl.obolibrary.org/obo/GO_0071806 protein transmembrane transport The import of proteins across the outer and inner mitochondrial membranes into the matrix. Unfolded proteins enter the mitochondrial matrix with a chaperone protein; the information required to target the precursor protein from the cytosol to the mitochondrial matrix is contained within its N-terminal matrix-targeting sequence. Translocation of precursors to the matrix occurs at the rare sites where the outer and inner membranes are close together. http://purl.obolibrary.org/obo/CL_0002543 vein endothelial cell http://purl.obolibrary.org/obo/CL_0000071 blood vessel endothelial cell An endothelial cell that is part of the vein. http://purl.obolibrary.org/obo/CL_0002544 aortic endothelial cell http://purl.obolibrary.org/obo/CL_1000413 endothelial cell of artery An arterial endothelial cell that is part of the aorta endothelium. http://purl.obolibrary.org/obo/GO_0030162 regulation of proteolysis http://purl.obolibrary.org/obo/GO_0051246 regulation of protein metabolic process Any process that modulates the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein. http://purl.obolibrary.org/obo/CL_0002545 thoracic aorta endothelial cell http://purl.obolibrary.org/obo/CL_0002544 aortic endothelial cell An endothelial cell that is part of the thoracic endothelium. http://purl.obolibrary.org/obo/CL_0002546 embryonic blood vessel endothelial progenitor cell http://purl.obolibrary.org/obo/CL_0000222 mesodermal cell An endothelial progenitor cell that participates in angiogenesis during development. http://purl.obolibrary.org/obo/GO_0030167 proteoglycan catabolic process http://purl.obolibrary.org/obo/GO_0006516 glycoprotein catabolic process The chemical reactions and pathways resulting in the breakdown of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans. http://purl.obolibrary.org/obo/CL_0002547 fibroblast of the aortic adventitia http://purl.obolibrary.org/obo/CL_1000306 fibroblast of tunica adventitia of artery A fibroblast of the aortic adventitia. http://purl.obolibrary.org/obo/GO_0030171 voltage-gated proton channel activity http://purl.obolibrary.org/obo/GO_0015252 proton channel activity Enables the transmembrane transfer of a proton by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. http://purl.obolibrary.org/obo/CL_0002548 fibroblast of cardiac tissue http://purl.obolibrary.org/obo/CL_0002494 cardiocyte A fibroblast that is part of the heart. http://purl.obolibrary.org/obo/GO_0030184 nitric oxide transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity Enables the transfer of nitric oxide, nitrogen monoxide, from one side of a membrane to the other. http://purl.obolibrary.org/obo/CL_0002549 fibroblast of choroid plexus http://purl.obolibrary.org/obo/CL_0002319 neural cell A fibroblast that is part of the choroid plexus. http://purl.obolibrary.org/obo/GO_0030185 nitric oxide transport http://purl.obolibrary.org/obo/GO_0071705 nitrogen compound transport The directed movement of nitric oxide, nitrogen monoxide, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/CL_0002550 fibroblast of the conjunctiva http://purl.obolibrary.org/obo/CL_0000057 fibroblast A fibroblast that is part of the conjuctiva of the eye. http://purl.obolibrary.org/obo/GO_0030186 melatonin metabolic process http://purl.obolibrary.org/obo/GO_0042445 hormone metabolic process The chemical reactions and pathways involving melatonin (N-acetyl-5-methoxytryptamine). http://purl.obolibrary.org/obo/CL_0002551 fibroblast of dermis http://purl.obolibrary.org/obo/CL_0002620 skin fibroblast Any skin fibroblast that is part of some dermis. http://purl.obolibrary.org/obo/CL_0002552 fibroblast of gingiva http://purl.obolibrary.org/obo/CL_0000057 fibroblast Any fibroblast that is part of some gingiva. http://purl.obolibrary.org/obo/GO_0030187 melatonin biosynthetic process http://purl.obolibrary.org/obo/GO_0042435 indole-containing compound biosynthetic process The chemical reactions and pathways resulting in the formation of melatonin (N-acetyl-5-methoxytryptamine). http://purl.obolibrary.org/obo/CL_0002553 fibroblast of lung http://purl.obolibrary.org/obo/CL_0000057 fibroblast A fibroblast that is part of lung. http://purl.obolibrary.org/obo/GO_0030199 collagen fibril organization http://purl.obolibrary.org/obo/GO_0030198 extracellular matrix organization Any process that determines the size and arrangement of collagen fibrils within an extracellular matrix. http://purl.obolibrary.org/obo/CL_0002554 fibroblast of lymphatic vessel http://purl.obolibrary.org/obo/CL_0000057 fibroblast A fibroblast of the lymphatic system. http://purl.obolibrary.org/obo/GO_0030202 heparin proteoglycan metabolic process http://purl.obolibrary.org/obo/GO_0006029 proteoglycan metabolic process The chemical reactions and pathways involving heparin proteoglycans, which consist of a core protein linked to a heparin glycosaminoglycan. The heparin chain is composed of the repeating disaccharide unit beta-(1,4)-N-acetyl-D-glucosamine-alpha-(1,4)-hexuronic acid, the former being either sulfated or deacetylated on its amino group as well as sulfated on one of its hydroxyl groups, and the latter being e a mixture of sulfated and nonsulfated D-glucuronic and L-iduronic acids. Heparin is similar to heparan sulfate but it contains more N-sulfate and O-sulfate groups. Heparin proteoglycans are stored selectively in the secretory granules of mammalian mast cells. http://purl.obolibrary.org/obo/CL_0002555 fibroblast of mammary gland http://purl.obolibrary.org/obo/CL_0000057 fibroblast A fibroblast that is part of the mammary gland. http://purl.obolibrary.org/obo/CL_0002556 fibroblast of periodontium http://purl.obolibrary.org/obo/CL_0000057 fibroblast A fibroblast of the periodontium. http://purl.obolibrary.org/obo/GO_0030210 heparin proteoglycan biosynthetic process http://purl.obolibrary.org/obo/GO_0180064 protein O-linked glycosylation via xylose The chemical reactions and pathways resulting in the formation of heparin proteoglycans, which consist of a core protein linked to a heparin glycosaminoglycan. The heparin chain is composed of the repeating disaccharide unit beta-(1,4)-N-acetyl-D-glucosamine-alpha-(1,4)-hexuronic acid, the former being either sulfated or deacetylated on its amino group as well as sulfated on one of its hydroxyl groups, and the latter being a mixture of sulfated and nonsulfated D-glucuronic and L-iduronic acids. Heparin is similar to heparan sulfate but it contains more N-sulfate and O-sulfate groups. Heparin chains are covalently linked to serine/threonine residues (O-linked) of the core protein via a tetrasaccharide linker sequence (xylose-galactose-galactose-glucuronate). http://purl.obolibrary.org/obo/CL_0002557 fibroblast of pulmonary artery http://purl.obolibrary.org/obo/CL_0000057 fibroblast A fibroblast of pulmonary artery. http://purl.obolibrary.org/obo/CL_0002558 fibroblast of villous mesenchyme http://purl.obolibrary.org/obo/CL_0000057 fibroblast A fibroblast that is part of villous mesenchyme. http://purl.obolibrary.org/obo/GO_0030211 heparin proteoglycan catabolic process http://purl.obolibrary.org/obo/GO_0030202 heparin proteoglycan metabolic process The chemical reactions and pathways resulting in the breakdown of heparin proteoglycans, which consist of a core protein linked to a heparin glycosaminoglycan. The heparin chain is composed of the repeating disaccharide unit beta-(1,4)-N-acetyl-D-glucosamine-alpha-(1,4)-hexuronic acid, the former being either sulfated or deacetylated on its amino group as well as sulfated on one of its hydroxyl groups and the latter being a mixture of sulfated and nonsulfated D-glucuronic and L-iduronic acids. Heparin is similar to heparan sulfate but it contains more N-sulfate and O-sulfate groups. http://purl.obolibrary.org/obo/CL_0002559 hair follicle cell http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell An animal cell that is part of a hair follicle. http://purl.obolibrary.org/obo/CL_0002560 inner root sheath cell http://purl.obolibrary.org/obo/CL_0002559 hair follicle cell An epithelial cell that resides in the inner root sheath of the hair follicle. http://purl.obolibrary.org/obo/GO_0030212 hyaluronan metabolic process http://purl.obolibrary.org/obo/GO_0030203 glycosaminoglycan metabolic process The chemical reactions and pathways involving hyaluronan, the naturally occurring anionic form of hyaluronic acid. Hyaluronan is a type of non-sulfated glycosaminoglycan composed of the repeating disaccharide unit beta(1,4)-D-glucuronic acid-beta(1,3)-N-acetyl-D-glucosamine. http://purl.obolibrary.org/obo/CL_0002561 outer root sheath cell http://purl.obolibrary.org/obo/CL_0002559 hair follicle cell An epithelial cell that is part of the outer root sheath. http://purl.obolibrary.org/obo/CL_0002562 hair germinal matrix cell http://purl.obolibrary.org/obo/CL_0002559 hair follicle cell An epidermal cell that is part of the germinal matrix. http://purl.obolibrary.org/obo/GO_0030213 hyaluronan biosynthetic process http://purl.obolibrary.org/obo/GO_0030212 hyaluronan metabolic process The chemical reactions and pathways resulting in the formation of hyaluronan, the naturally occurring anionic form of hyaluronic acid. Hyaluronan is a type of non-sulfated glycosaminoglycan composed of the repeating disaccharide unit beta(1,4)-D-glucuronic acid-beta(1,3)-N-acetyl-D-glucosamine. http://purl.obolibrary.org/obo/CL_0002563 intestinal epithelial cell http://purl.obolibrary.org/obo/CL_0002251 epithelial cell of alimentary canal An epithelial cell of the lining of the intestine. http://purl.obolibrary.org/obo/CL_0002564 nucleus pulposus cell of intervertebral disc http://purl.obolibrary.org/obo/CL_0002320 connective tissue cell A connective tissue cell of the nucleus pulposus cell of intervertebral disc. http://purl.obolibrary.org/obo/GO_0030214 hyaluronan catabolic process http://purl.obolibrary.org/obo/GO_0030212 hyaluronan metabolic process The chemical reactions and pathways resulting in the breakdown of hyaluronan, the naturally occurring anionic form of hyaluronic acid. Hyaluronan is a type of non-sulfated glycosaminoglycan composed of the repeating disaccharide unit beta(1,4)-D-glucuronic acid-beta(1,3)-N-acetyl-D-glucosamine. http://purl.obolibrary.org/obo/CL_0002565 iris pigment epithelial cell http://purl.obolibrary.org/obo/CL_0000342 pigment cell (sensu Vertebrata) A pigment cell located in the epithelium of the iris. http://purl.obolibrary.org/obo/CL_0002566 dark melanocyte http://purl.obolibrary.org/obo/CL_0000148 melanocyte A melanocyte that appears darker due to content or amount of melanin granules. http://purl.obolibrary.org/obo/GO_0030218 erythrocyte differentiation http://purl.obolibrary.org/obo/GO_0030099 myeloid cell differentiation The process in which a myeloid precursor cell acquires specializes features of an erythrocyte. http://purl.obolibrary.org/obo/CL_0002567 light melanocyte http://purl.obolibrary.org/obo/CL_0000148 melanocyte A melanocyte that appears lighter in color. http://purl.obolibrary.org/obo/CL_0002568 mesenchymal stem cell of Wharton's jelly http://purl.obolibrary.org/obo/CL_0002569 mesenchymal stem cell of umbilical cord A mesenchymal stem cell that is part of Wharton's jelly. http://purl.obolibrary.org/obo/GO_0030219 megakaryocyte differentiation http://purl.obolibrary.org/obo/GO_0030099 myeloid cell differentiation The process in which a myeloid precursor cell acquires specializes features of a megakaryocyte. http://purl.obolibrary.org/obo/CL_0002569 mesenchymal stem cell of umbilical cord http://purl.obolibrary.org/obo/CL_0000349 extraembryonic cell A mesenchymal stem cell of the umbilical cord. http://purl.obolibrary.org/obo/CL_0002570 mesenchymal stem cell of adipose tissue http://purl.obolibrary.org/obo/CL_0000134 mesenchymal stem cell A mesenchymal stem cell of adipose tissue. http://purl.obolibrary.org/obo/GO_0030220 platelet formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process in which platelets bud from long processes extended by megakaryocytes. http://purl.obolibrary.org/obo/CL_0002571 hepatic mesenchymal stem cell http://purl.obolibrary.org/obo/CL_0002195 hepatic stem cell A mesenchymal stem cell of liver. http://purl.obolibrary.org/obo/CL_0002572 vertebral mesenchymal stem cell http://purl.obolibrary.org/obo/CL_0001035 bone cell A mesenchymal stem cell of the vertebrae. http://purl.obolibrary.org/obo/GO_0030221 basophil differentiation http://purl.obolibrary.org/obo/GO_0030851 granulocyte differentiation The process in which a relatively unspecialized myeloid precursor cell acquires specialized features of a basophil cell. http://purl.obolibrary.org/obo/CL_0002573 Schwann cell http://purl.obolibrary.org/obo/CL_0000125 glial cell A glial cell that myelinates or ensheathes axons in the peripheral nervous system. http://purl.obolibrary.org/obo/CL_0002574 stromal cell of pancreas http://purl.obolibrary.org/obo/CL_0000499 stromal cell A stromal cell of the pancreas. http://purl.obolibrary.org/obo/GO_0030222 eosinophil differentiation http://purl.obolibrary.org/obo/GO_0030851 granulocyte differentiation The process in which a relatively unspecialized myeloid precursor cell acquires the specializes features of an eosinophil. http://purl.obolibrary.org/obo/CL_0002575 central nervous system pericyte http://purl.obolibrary.org/obo/CL_0002319 neural cell A pericyte of the central nervous system. http://purl.obolibrary.org/obo/CL_0002576 perineurial cell http://purl.obolibrary.org/obo/CL_0002320 connective tissue cell A glial cell that is part of the perineurium. This cell type has thin long bipolar cytoplasmic processes, pinocytotic vesicles, fragments of external lamina and/or external lamina-like material, attachment plaques, and desmosome-like junctions. Perineurial cells historically have been referred to as fibroblasts because of shape; however, unlike fibroblasts, a perineurial cell: does not have a compact nucleus and large endoplasmic reticulum; does have a double basement membrane opposed to a single basal lamina; is carefully joined to other perineurial cells by tight junctions into a single sheet as opposed to arranged in a large mass; and finally, can surround a small axon bundle at a nerve terminal whereas a fibroblast cannot. http://purl.obolibrary.org/obo/GO_0030223 neutrophil differentiation http://purl.obolibrary.org/obo/GO_0030851 granulocyte differentiation The process in which a myeloid precursor cell acquires the specialized features of a neutrophil. http://purl.obolibrary.org/obo/GO_0030224 monocyte differentiation http://purl.obolibrary.org/obo/GO_1903131 mononuclear cell differentiation The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a monocyte. http://purl.obolibrary.org/obo/CL_0002577 placental epithelial cell http://purl.obolibrary.org/obo/CL_0000349 extraembryonic cell An epithelial cell of the placenta. http://purl.obolibrary.org/obo/GO_0030252 growth hormone secretion http://purl.obolibrary.org/obo/GO_0030072 peptide hormone secretion The regulated release of growth hormone from secretory granules into the blood. http://purl.obolibrary.org/obo/CL_0002578 mesenteric preadipocyte http://purl.obolibrary.org/obo/CL_0002334 preadipocyte A preadipocyte found in mesenteric tissue. http://purl.obolibrary.org/obo/GO_0030263 apoptotic chromosome condensation http://purl.obolibrary.org/obo/GO_0030261 chromosome condensation The compaction of chromatin during apoptosis. http://purl.obolibrary.org/obo/GO_0030264 nuclear fragmentation involved in apoptotic nuclear change http://purl.obolibrary.org/obo/GO_0071763 nuclear membrane organization The breakdown of the nucleus into small membrane-bounded compartments, or blebs, each of which contain compacted DNA. http://purl.obolibrary.org/obo/CL_0002579 omentum preadipocyte http://purl.obolibrary.org/obo/CL_0002334 preadipocyte A preadipocyte that is part of an omentum. http://purl.obolibrary.org/obo/GO_0030278 regulation of ossification http://purl.obolibrary.org/obo/GO_0051239 regulation of multicellular organismal process Any process that modulates the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance. http://purl.obolibrary.org/obo/CL_0002580 preadipocyte of the breast http://purl.obolibrary.org/obo/CL_4006000 fibroblast of breast A preadipocyte that is part of the breast. http://purl.obolibrary.org/obo/CL_0002581 perirenal preadipocyte http://purl.obolibrary.org/obo/CL_0002334 preadipocyte A preadipocyte that is part of a perirenal fat tissue. http://purl.obolibrary.org/obo/GO_0030279 negative regulation of ossification http://purl.obolibrary.org/obo/GO_0030278 regulation of ossification Any process that stops, prevents, or reduces the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance. http://purl.obolibrary.org/obo/CL_0002582 visceral preadipocyte http://purl.obolibrary.org/obo/CL_0002334 preadipocyte A preadipocyte that is part of visceral tissue. http://purl.obolibrary.org/obo/GO_0030282 bone mineralization http://purl.obolibrary.org/obo/GO_0031214 biomineral tissue development The deposition of hydroxyapatite, a form of calcium phosphate with the formula Ca10(PO4)6(OH)2, in bone tissue. http://purl.obolibrary.org/obo/CL_0002584 renal cortical epithelial cell http://purl.obolibrary.org/obo/CL_0002681 kidney cortical cell An epithelial cell of the kidney cortex. http://purl.obolibrary.org/obo/GO_0030307 positive regulation of cell growth http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the frequency, rate, extent or direction of cell growth. http://purl.obolibrary.org/obo/CL_0002585 retinal blood vessel endothelial cell http://purl.obolibrary.org/obo/CL_0009004 retinal cell A blood vessel endothelial cell that is part of the retina. http://purl.obolibrary.org/obo/GO_0030308 negative regulation of cell growth http://purl.obolibrary.org/obo/GO_0045926 negative regulation of growth Any process that stops, prevents, or reduces the frequency, rate, extent or direction of cell growth. http://purl.obolibrary.org/obo/CL_0002586 retinal pigment epithelial cell http://purl.obolibrary.org/obo/CL_0009004 retinal cell An epithelial cell of the retinal pigmented epithelium. http://purl.obolibrary.org/obo/GO_0030316 osteoclast differentiation http://purl.obolibrary.org/obo/GO_0002573 myeloid leukocyte differentiation The process in which a relatively unspecialized monocyte acquires the specialized features of an osteoclast. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue. http://purl.obolibrary.org/obo/CL_0002588 smooth muscle cell of the umbilical vein http://purl.obolibrary.org/obo/CL_0019018 blood vessel smooth muscle cell A smooth muscle cell of the umbilical vein. http://purl.obolibrary.org/obo/CL_0002589 smooth muscle cell of the brachiocephalic vasculature http://purl.obolibrary.org/obo/CL_0019018 blood vessel smooth muscle cell A smooth muscle cell of the bachiocephalic vasculature. http://purl.obolibrary.org/obo/GO_0030318 melanocyte differentiation http://purl.obolibrary.org/obo/GO_0050931 pigment cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a melanocyte. http://purl.obolibrary.org/obo/GO_0030323 respiratory tube development http://purl.obolibrary.org/obo/GO_0048513 animal organ development The process whose specific outcome is the progression of the respiratory tube over time, from its formation to the mature structure. The respiratory tube is assumed to mean any tube in the respiratory tract. http://purl.obolibrary.org/obo/CL_0002590 smooth muscle cell of the brain vasculature http://purl.obolibrary.org/obo/CL_0002319 neural cell A vascular associated smooth muscle cell of the brain vasculature. http://purl.obolibrary.org/obo/CL_0002591 smooth muscle cell of the pulmonary artery http://purl.obolibrary.org/obo/CL_0019018 blood vessel smooth muscle cell A smooth muscle of the pulmonary artery. http://purl.obolibrary.org/obo/GO_0030324 lung development http://purl.obolibrary.org/obo/GO_0048513 animal organ development The process whose specific outcome is the progression of the lung over time, from its formation to the mature structure. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the esophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into tubes ending in small air cells, in the walls of which the blood circulates in a fine network of capillaries. In mammals the lungs are more or less divided into lobes, and each lung occupies a separate cavity in the thorax. http://purl.obolibrary.org/obo/CL_0002592 smooth muscle cell of the coronary artery http://purl.obolibrary.org/obo/CL_0019018 blood vessel smooth muscle cell A smooth muscle cell of the coronary artery. http://purl.obolibrary.org/obo/CL_0002593 smooth muscle cell of the internal thoracic artery http://purl.obolibrary.org/obo/CL_0002595 smooth muscle cell of the subclavian artery A smooth muscle of the internal thoracic artery. http://purl.obolibrary.org/obo/GO_0030325 adrenal gland development http://purl.obolibrary.org/obo/GO_0048732 gland development The process whose specific outcome is the progression of the adrenal gland over time, from its formation to the mature structure. This gland can either be a discrete structure located bilaterally above each kidney, or a cluster of cells in the head kidney that perform the functions of the adrenal gland. In either case, this organ consists of two cells types, aminergic chromaffin cells and steroidogenic cortical cells. http://purl.obolibrary.org/obo/CL_0002594 smooth muscle cell of the umbilical artery http://purl.obolibrary.org/obo/CL_0019018 blood vessel smooth muscle cell A smooth muscle cell of the umbilical artery. http://purl.obolibrary.org/obo/CL_0002595 smooth muscle cell of the subclavian artery http://purl.obolibrary.org/obo/CL_0019018 blood vessel smooth muscle cell A smooth muscle cell of the subclavian artery. http://purl.obolibrary.org/obo/GO_0030331 nuclear estrogen receptor binding http://purl.obolibrary.org/obo/GO_0016922 nuclear receptor binding Binding to a nuclear estrogen receptor. http://purl.obolibrary.org/obo/CL_0002596 smooth muscle cell of the carotid artery http://purl.obolibrary.org/obo/CL_0019018 blood vessel smooth muscle cell Smooth muscle cell of the carotid artery. http://purl.obolibrary.org/obo/CL_0002597 smooth muscle cell of bladder http://purl.obolibrary.org/obo/CL_1001319 bladder cell A smooth muscle cell of the bladder. http://purl.obolibrary.org/obo/GO_0030382 sperm mitochondrion organization http://purl.obolibrary.org/obo/GO_0007005 mitochondrion organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of sperm mitochondria; the process in which they take on their characteristic morphology; they are flattened, elongated, and arranged circumferentially into a tight helical coil around the tail-dense fibers of the mature sperm. http://purl.obolibrary.org/obo/CL_0002598 bronchial smooth muscle cell http://purl.obolibrary.org/obo/CL_0019019 tracheobronchial smooth muscle cell Any smooth muscle cell that is part of some bronchus. http://purl.obolibrary.org/obo/CL_0002599 smooth muscle cell of the esophagus http://purl.obolibrary.org/obo/CL_0000192 smooth muscle cell A smooth muscle cell of the esophagus. http://purl.obolibrary.org/obo/GO_0030421 defecation http://purl.obolibrary.org/obo/GO_0022600 digestive system process The expulsion of feces from the rectum. http://purl.obolibrary.org/obo/CL_0002600 smooth muscle cell of trachea http://purl.obolibrary.org/obo/CL_0019019 tracheobronchial smooth muscle cell A smooth muscle cell of the trachea. http://purl.obolibrary.org/obo/CL_0002601 uterine smooth muscle cell http://purl.obolibrary.org/obo/CL_0000192 smooth muscle cell A smooth muscle cell of the uterus. http://purl.obolibrary.org/obo/GO_0030424 axon http://purl.obolibrary.org/obo/GO_0043005 neuron projection The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter. http://purl.obolibrary.org/obo/CL_0002602 annulus pulposus cell http://purl.obolibrary.org/obo/CL_0002320 connective tissue cell Any connective tissue cell that is part of some annulus fibrosus disci intervertebralis. http://purl.obolibrary.org/obo/CL_0002603 astrocyte of the cerebellum http://purl.obolibrary.org/obo/CL_2000005 brain macroglial cell An astrocyte of the cerebellum. http://purl.obolibrary.org/obo/GO_0030425 dendrite http://purl.obolibrary.org/obo/GO_0043005 neuron projection A neuron projection that has a short, tapering, morphology. Dendrites receive and integrate signals from other neurons or from sensory stimuli, and conduct nerve impulses towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body. http://purl.obolibrary.org/obo/CL_0002604 hippocampal astrocyte http://purl.obolibrary.org/obo/CL_1001580 hippocampal glial cell An astrocyte that is part of the hippocampus. http://purl.obolibrary.org/obo/CL_0002605 astrocyte of the cerebral cortex http://purl.obolibrary.org/obo/CL_1001579 cerebral cortex glial cell A transcriptomically distinct astrocyte that is found in the cerebral cortex. http://purl.obolibrary.org/obo/GO_0030432 peristalsis http://purl.obolibrary.org/obo/GO_0014821 phasic smooth muscle contraction A wavelike sequence of involuntary muscular contraction and relaxation that passes along a tubelike structure, such as the intestine, impelling the contents onwards. http://purl.obolibrary.org/obo/CL_0002606 astrocyte of the spinal cord http://purl.obolibrary.org/obo/CL_0000127 astrocyte An astrocyte of the spinal cord. http://purl.obolibrary.org/obo/GO_0030435 sporulation resulting in formation of a cellular spore http://purl.obolibrary.org/obo/GO_0043934 sporulation The process in which a relatively unspecialized cell acquires the specialized features of a cellular spore, a cell form that can be used for dissemination, for survival of adverse conditions because of its heat and desiccation resistance, and/or for reproduction. http://purl.obolibrary.org/obo/CL_0002607 migratory enteric neural crest cell http://purl.obolibrary.org/obo/CL_0000333 migratory neural crest cell A neural crest cell that gives rise to cells of the enteric nervous system. http://purl.obolibrary.org/obo/CL_0002608 hippocampal neuron http://purl.obolibrary.org/obo/CL_0010012 cerebral cortex neuron A neuron with a soma found in the hippocampus. http://purl.obolibrary.org/obo/GO_0030485 smooth muscle contractile fiber http://purl.obolibrary.org/obo/GO_0043292 contractile muscle fiber The contractile fiber of smooth muscle cells. http://purl.obolibrary.org/obo/CL_0002610 raphe nuclei neuron http://purl.obolibrary.org/obo/CL_2000029 central nervous system neuron A neuron of the raphe nuclei. http://purl.obolibrary.org/obo/GO_0030500 regulation of bone mineralization http://purl.obolibrary.org/obo/GO_0070167 regulation of biomineral tissue development Any process that modulates the frequency, rate or extent of bone mineralization. http://purl.obolibrary.org/obo/CL_0002611 neuron of the dorsal spinal cord http://purl.obolibrary.org/obo/CL_2000029 central nervous system neuron A CNS neuron of the dorsal spinal cord. http://purl.obolibrary.org/obo/GO_0030501 positive regulation of bone mineralization http://purl.obolibrary.org/obo/GO_0070169 positive regulation of biomineral tissue development Any process that activates or increases the frequency, rate or extent of bone mineralization. http://purl.obolibrary.org/obo/CL_0002612 neuron of the ventral spinal cord http://purl.obolibrary.org/obo/CL_2000029 central nervous system neuron A neuron of the ventral spinal cord. http://purl.obolibrary.org/obo/GO_0030502 negative regulation of bone mineralization http://purl.obolibrary.org/obo/GO_0070168 negative regulation of biomineral tissue development Any process that stops, prevents, or reduces the frequency, rate or extent of bone mineralization. http://purl.obolibrary.org/obo/CL_0002613 striatum neuron http://purl.obolibrary.org/obo/CL_0012001 neuron of the forebrain A neuron of the striatum. http://purl.obolibrary.org/obo/GO_0030539 male genitalia development http://purl.obolibrary.org/obo/GO_0061458 reproductive system development The process whose specific outcome is the progression of the male genitalia over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/CL_0002614 neuron of the substantia nigra http://purl.obolibrary.org/obo/CL_2000029 central nervous system neuron A neuron of the substantia nigra. http://purl.obolibrary.org/obo/GO_0030573 bile acid catabolic process http://purl.obolibrary.org/obo/GO_0008206 bile acid metabolic process The chemical reactions and pathways resulting in the breakdown of bile acids, any of a group of steroid carboxylic acids occurring in bile. http://purl.obolibrary.org/obo/CL_0002615 adipocyte of omentum tissue http://purl.obolibrary.org/obo/CL_0000136 adipocyte An adipocyte that is part of omentum tissue. http://purl.obolibrary.org/obo/GO_0030593 neutrophil chemotaxis http://purl.obolibrary.org/obo/GO_1990266 neutrophil migration The directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding. http://purl.obolibrary.org/obo/CL_0002616 perirenal adipocyte http://purl.obolibrary.org/obo/CL_0000136 adipocyte An adipocyte of perirenal fat tissue. http://purl.obolibrary.org/obo/CL_0002617 adipocyte of breast http://purl.obolibrary.org/obo/CL_0000136 adipocyte An adipocyte that is part of the breast. http://purl.obolibrary.org/obo/GO_0030643 intracellular phosphate ion homeostasis http://purl.obolibrary.org/obo/GO_0055062 phosphate ion homeostasis A homeostatic process involved in the maintenance of a steady state level of phosphate ions within a cell. http://purl.obolibrary.org/obo/CL_0002618 endothelial cell of umbilical vein http://purl.obolibrary.org/obo/CL_0002543 vein endothelial cell An endothelial cell of the umbilical vein. http://purl.obolibrary.org/obo/GO_0030659 cytoplasmic vesicle membrane http://purl.obolibrary.org/obo/GO_0012506 vesicle membrane The lipid bilayer surrounding a cytoplasmic vesicle. http://purl.obolibrary.org/obo/CL_0002619 adult endothelial progenitor cell http://purl.obolibrary.org/obo/CL_0000566 angioblastic mesenchymal cell An adult angioblastic cell released from the bone marrow, or from the kidney in some teleost species, capable of blood circulation and participation in angiogenesis by differentiating into blood vessel endothelial cells. http://purl.obolibrary.org/obo/GO_0030661 chitosome membrane http://purl.obolibrary.org/obo/GO_0030659 cytoplasmic vesicle membrane The lipid bilayer surrounding a chitosome. http://purl.obolibrary.org/obo/CL_0002620 skin fibroblast http://purl.obolibrary.org/obo/CL_0000057 fibroblast A fibroblast of skin. http://purl.obolibrary.org/obo/GO_0030718 germ-line stem cell population maintenance http://purl.obolibrary.org/obo/GO_0019827 stem cell population maintenance Any process by which an organism or tissue maintains a population of germ-line stem cells. http://purl.obolibrary.org/obo/CL_0002621 gingival epithelial cell http://purl.obolibrary.org/obo/CL_1001576 oral mucosa squamous cell Any stratified squamous epithelial cell that is part of some gingival epithelium. http://purl.obolibrary.org/obo/GO_0030720 oocyte localization involved in germarium-derived egg chamber formation http://purl.obolibrary.org/obo/GO_0051674 localization of cell Directed movement of the oocyte, following its specification, from its original central position in the cyst to a posterior position relative to the nurse cells of the egg chamber, and its maintenance in this posterior location. This is the first sign of anterior-posterior asymmetry in the developing egg chamber. http://purl.obolibrary.org/obo/CL_0002622 prostate stromal cell http://purl.obolibrary.org/obo/CL_0000499 stromal cell A stromal cell of the prostate. http://purl.obolibrary.org/obo/CL_0002623 acinar cell of salivary gland http://purl.obolibrary.org/obo/CL_1001596 salivary gland glandular cell An acinar cell that is part of the salivary gland epithelium, responsible for synthesizing and secreting the primary saliva essential for oral digestion, antimicrobial defense, and mucosal immunity. It features apical-basal polarity with apical secretory granules, and tight junctions that maintain polarity and regulate calcium-dependent saliva exocytosis triggered by parasympathetic and sympathetic signals (Ambudkar, 2015). This cell functions in coordination with contractile myoepithelial cells, which aid saliva flow through the ducts into the oral cavity (Khan et al., 2022). In mice and humans, acinar cell development relies on the transcription factor SOX2 (Emmerson et al., 2017), with self-renewal achieved primarily through acinar cell self-duplication and supported by progenitor populations during injury and regeneration (Aure et al., 2016). http://purl.obolibrary.org/obo/GO_0030808 regulation of nucleotide biosynthetic process http://purl.obolibrary.org/obo/GO_0009889 regulation of biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nucleotides. http://purl.obolibrary.org/obo/GO_0030809 negative regulation of nucleotide biosynthetic process http://purl.obolibrary.org/obo/GO_0009890 negative regulation of biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nucleotides. http://purl.obolibrary.org/obo/CL_0002624 paneth cell of the appendix http://purl.obolibrary.org/obo/CL_1001585 appendix glandular cell A paneth cell of the appendix. http://purl.obolibrary.org/obo/GO_0030810 positive regulation of nucleotide biosynthetic process http://purl.obolibrary.org/obo/GO_0009891 positive regulation of biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nucleotides. http://purl.obolibrary.org/obo/GO_0030811 regulation of nucleotide catabolic process http://purl.obolibrary.org/obo/GO_0009894 regulation of catabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of nucleotides. http://purl.obolibrary.org/obo/CL_0002625 seminiferous tubule epithelial cell http://purl.obolibrary.org/obo/CL_0000077 mesothelial cell A cell of the seminiferous tubule epithelium. http://purl.obolibrary.org/obo/GO_0030812 negative regulation of nucleotide catabolic process http://purl.obolibrary.org/obo/GO_0009895 negative regulation of catabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of nucleotides. http://purl.obolibrary.org/obo/GO_0030813 positive regulation of nucleotide catabolic process http://purl.obolibrary.org/obo/GO_0009896 positive regulation of catabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of nucleotides. http://purl.obolibrary.org/obo/CL_0002626 immature astrocyte http://purl.obolibrary.org/obo/CL_0000127 astrocyte An immature astrocyte. http://purl.obolibrary.org/obo/GO_0030849 autosome http://purl.obolibrary.org/obo/GO_0005694 chromosome Any chromosome other than a sex chromosome. http://purl.obolibrary.org/obo/CL_0002627 mature astrocyte http://purl.obolibrary.org/obo/CL_0000127 astrocyte A mature astrocyte that is capable of producing cytokines. http://purl.obolibrary.org/obo/GO_0030850 prostate gland development http://purl.obolibrary.org/obo/GO_0048732 gland development The process whose specific outcome is the progression of the prostate gland over time, from its formation to the mature structure. The prostate gland is a partly muscular, partly glandular body that is situated near the base of the mammalian male urethra and secretes an alkaline viscid fluid which is a major constituent of the ejaculatory fluid. http://purl.obolibrary.org/obo/CL_0002628 immature microglial cell http://purl.obolibrary.org/obo/CL_0000129 microglial cell An immature microglial cell with a ramified morphology. http://purl.obolibrary.org/obo/CL_0002629 mature microglial cell http://purl.obolibrary.org/obo/CL_0000129 microglial cell A mature microglial cell that has changed shape to an amoeboid morphology and is capable of cytokine production and antigen presentation. http://purl.obolibrary.org/obo/CL_0002630 actinomycete-type spore http://purl.obolibrary.org/obo/CL_0000520 prokaryotic cell A spore formed from bacteria in the order Actinomycetales. http://purl.obolibrary.org/obo/GO_0030851 granulocyte differentiation http://purl.obolibrary.org/obo/GO_0002573 myeloid leukocyte differentiation The process in which a myeloid precursor cell acquires the specialized features of a granulocyte. Granulocytes are a class of leukocytes characterized by the presence of granules in their cytoplasm. These cells are active in allergic immune reactions such as arthritic inflammation and rashes. This class includes basophils, eosinophils and neutrophils. http://purl.obolibrary.org/obo/CL_0002631 epithelial cell of upper respiratory tract http://purl.obolibrary.org/obo/CL_0002368 respiratory tract epithelial cell Any epithelial cell that is part of some upper respiratory tract epithelium. http://purl.obolibrary.org/obo/GO_0030852 regulation of granulocyte differentiation http://purl.obolibrary.org/obo/GO_0002761 regulation of myeloid leukocyte differentiation Any process that modulates the frequency, rate or extent of granulocyte differentiation. http://purl.obolibrary.org/obo/CL_0002632 epithelial cell of lower respiratory tract http://purl.obolibrary.org/obo/CL_0002368 respiratory tract epithelial cell Any epithelial cell that is part of some lower respiratory tract epithelium. http://purl.obolibrary.org/obo/GO_0030853 negative regulation of granulocyte differentiation http://purl.obolibrary.org/obo/GO_0030852 regulation of granulocyte differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of granulocyte differentiation. http://purl.obolibrary.org/obo/CL_0002633 respiratory basal cell http://purl.obolibrary.org/obo/CL_0000646 basal cell A basal cell in the respiratory tract. http://purl.obolibrary.org/obo/GO_0030854 positive regulation of granulocyte differentiation http://purl.obolibrary.org/obo/GO_0030852 regulation of granulocyte differentiation Any process that activates or increases the frequency, rate or extent of granulocyte differentiation. http://purl.obolibrary.org/obo/CL_0002634 epithelial cell of anal column http://purl.obolibrary.org/obo/CL_0002253 epithelial cell of large intestine An epithelial cell of the anal column. http://purl.obolibrary.org/obo/GO_0030856 regulation of epithelial cell differentiation http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the frequency, rate or extent of epithelial cell differentiation. http://purl.obolibrary.org/obo/CL_0002635 nonkeratinized epithelial cell of anal column http://purl.obolibrary.org/obo/CL_0002634 epithelial cell of anal column A nonkeratinized epithelial cell of the anal canal. http://purl.obolibrary.org/obo/GO_0030858 positive regulation of epithelial cell differentiation http://purl.obolibrary.org/obo/GO_0045597 positive regulation of cell differentiation Any process that activates or increases the frequency, rate or extent of epithelial cell differentiation. http://purl.obolibrary.org/obo/CL_0002636 nonkeratinized epithelial cell of inferior part of anal canal http://purl.obolibrary.org/obo/CL_1000438 epithelial cell of wall of inferior part of anal canal A nonkeratinized cell epithleial cell of the inferior part of the anal canal. http://purl.obolibrary.org/obo/GO_0030878 thyroid gland development http://purl.obolibrary.org/obo/GO_0048732 gland development The process whose specific outcome is the progression of the thyroid gland over time, from its formation to the mature structure. The thyroid gland is an endoderm-derived gland that produces thyroid hormone. http://purl.obolibrary.org/obo/CL_0002637 keratinized epithelial cell of the anal canal http://purl.obolibrary.org/obo/CL_0002634 epithelial cell of anal column An epithelial cell of the anal canal that is keratinized. This cell type is found towards the lower, rectal end of the anal canal. http://purl.obolibrary.org/obo/GO_0030885 regulation of myeloid dendritic cell activation http://purl.obolibrary.org/obo/GO_0002694 regulation of leukocyte activation Any process that modulates the frequency or rate of myeloid dendritic cell activation. http://purl.obolibrary.org/obo/GO_0030886 negative regulation of myeloid dendritic cell activation http://purl.obolibrary.org/obo/GO_0030885 regulation of myeloid dendritic cell activation Any process that stops, prevents, or reduces the frequency, rate or extent of myeloid dendritic cell activation. http://purl.obolibrary.org/obo/CL_0002638 bronchioalveolar stem cell http://purl.obolibrary.org/obo/CL_0002633 respiratory basal cell A respiratory stem cell found at the junction of the terminal (conductive) bronchiole and the respiratory bronchiole. This cell types gives rise to alveolar cell types and club cells in response to lung injury. This cell type expresses markers Scgb1a1 and Sftpc. http://purl.obolibrary.org/obo/GO_0030887 positive regulation of myeloid dendritic cell activation http://purl.obolibrary.org/obo/GO_0030885 regulation of myeloid dendritic cell activation Any process that stimulates, induces or increases the rate of myeloid dendritic cell activation. http://purl.obolibrary.org/obo/CL_0002639 amniotic stem cell http://purl.obolibrary.org/obo/CL_0002323 amniocyte An amniotic stem cell is a mesenchymalstem cell extracted from amniotic fluid. Amniotic stem cells are able to differentiate into various tissue type such as skin, cartilage, cardiac tissue, nerves, muscle, and bone http://purl.obolibrary.org/obo/GO_0030888 regulation of B cell proliferation http://purl.obolibrary.org/obo/GO_0050864 regulation of B cell activation Any process that modulates the frequency, rate or extent of B cell proliferation. http://purl.obolibrary.org/obo/CL_0002640 amniotic epithelial stem cell http://purl.obolibrary.org/obo/CL_0000036 epithelial fate stem cell An epithelial fate stem cell derived form the amnion membrane. http://purl.obolibrary.org/obo/GO_0030889 negative regulation of B cell proliferation http://purl.obolibrary.org/obo/GO_0050869 negative regulation of B cell activation Any process that stops, prevents or reduces the rate or extent of B cell proliferation. http://purl.obolibrary.org/obo/CL_0002641 epithelial cell of esophageal gland proper http://purl.obolibrary.org/obo/CL_0002657 glandular cell of esophagus An epithelial cell of the esophageal gland proper. http://purl.obolibrary.org/obo/GO_0030890 positive regulation of B cell proliferation http://purl.obolibrary.org/obo/GO_0050871 positive regulation of B cell activation Any process that activates or increases the rate or extent of B cell proliferation. http://purl.obolibrary.org/obo/CL_0002642 epithelial cell of esophageal cardiac gland http://purl.obolibrary.org/obo/CL_0002657 glandular cell of esophagus An epithelial cell of the esophageal cardiac gland that occurs both in the proximal and distal esophagus, within the lamina propia. http://purl.obolibrary.org/obo/GO_0030900 forebrain development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the forebrain over time, from its formation to the mature structure. The forebrain is the anterior of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes especially the cerebral hemispheres, the thalamus, and the hypothalamus and especially in higher vertebrates is the main control center for sensory and associative information processing, visceral functions, and voluntary motor functions). http://purl.obolibrary.org/obo/CL_0002643 nonkeratinized cell of stratum corneum of esophageal epithelium http://purl.obolibrary.org/obo/CL_0002654 epithelial cell of stratum corneum of esophageal epithelium An epithelial cell of stratum corneum of esophageal epithelium that lacks keratin. http://purl.obolibrary.org/obo/CL_0002644 endo-epithelial cell of tympanic part of viscerocranial mucosa http://purl.obolibrary.org/obo/CL_0002261 endothelial cell of viscerocranial mucosa An endothelial cell of viscerocranial mucosa that is part of the tympanic region of the viscerocranial mucosa. http://purl.obolibrary.org/obo/GO_0030901 midbrain development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the midbrain over time, from its formation to the mature structure. The midbrain is the middle division of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes a ventral part containing the cerebral peduncles and a dorsal tectum containing the corpora quadrigemina and that surrounds the aqueduct of Sylvius connecting the third and fourth ventricles). http://purl.obolibrary.org/obo/CL_0002645 endo-epithelial cell of pharyngotympanic part of viscerocranial mucosa http://purl.obolibrary.org/obo/CL_0002261 endothelial cell of viscerocranial mucosa An endocranial viscerocranial mucosa cell that is part of viscerocranial mucosa. http://purl.obolibrary.org/obo/CL_0002651 endothelial cell of venous sinus of spleen http://purl.obolibrary.org/obo/CL_0002262 endothelial cell of sinusoid An endothelial cell that is part of the venous sinus of spleen. This endothelial cell has an elongated, spindle-shaped, flattened morphology that is parallel to long axis of sinus. This cell type rests on a basement membrane interrupted by numerous narrow slits. http://purl.obolibrary.org/obo/GO_0030902 hindbrain development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the hindbrain over time, from its formation to the mature structure. The hindbrain is the posterior of the three primary divisions of the developing chordate brain, or the corresponding part of the adult brain (in vertebrates, includes the cerebellum, pons, and medulla oblongata and controls the autonomic functions and equilibrium). http://purl.obolibrary.org/obo/CL_0002652 endothelial cell of high endothelial venule http://purl.obolibrary.org/obo/CL_1000414 endothelial cell of venule A venule endothelial cell that is cubodial, expresses leukocyte-specific receptors, and allows for passage of lymphocytes into bloodstream. http://purl.obolibrary.org/obo/CL_0002653 squamous endothelial cell http://purl.obolibrary.org/obo/CL_0000115 endothelial cell A squamous shaped endothelial cell. http://purl.obolibrary.org/obo/GO_0030903 notochord development http://purl.obolibrary.org/obo/GO_0048568 embryonic organ development The process whose specific outcome is the progression of the notochord over time, from its formation to the mature structure. The notochord is a mesoderm-derived structure located ventral of the developing nerve cord. In vertebrates, the notochord serves as a core around which other mesodermal cells form the vertebrae. In the most primitive chordates, which lack vertebrae, the notochord persists as a substitute for a vertebral column. http://purl.obolibrary.org/obo/CL_0002654 epithelial cell of stratum corneum of esophageal epithelium http://purl.obolibrary.org/obo/CL_0002252 epithelial cell of esophagus An epithelial cell of stratum corneum of esophageal epithelium. http://purl.obolibrary.org/obo/CL_0002655 epithelial cell of stratum spinosum of esophageal epithelium http://purl.obolibrary.org/obo/CL_0002252 epithelial cell of esophagus An epithelial cell of stratum spinosum of esophageal epithelium. http://purl.obolibrary.org/obo/GO_0030910 olfactory placode formation http://purl.obolibrary.org/obo/GO_0060788 ectodermal placode formation The formation of a thickening of the neural ectoderm in the head region of the vertebrate embryo which develops into the olfactory region of the nasal cavity. http://purl.obolibrary.org/obo/CL_0002656 glandular endometrial unciliated epithelial cell http://purl.obolibrary.org/obo/CL_0009084 glandular epithelial cell of endometrium A glandular epithelial cell of the endometrium. Following ovulation, these cells secrete a glycogen-rich substance known as histotroph or uterine milk, which nourishes the embryo if implantation occurs. http://purl.obolibrary.org/obo/GO_0030916 otic vesicle formation http://purl.obolibrary.org/obo/GO_0072175 epithelial tube formation The process resulting in the transition of the otic placode into the otic vesicle, a transient embryonic structure formed during development of the vertebrate inner ear. http://purl.obolibrary.org/obo/CL_0002657 glandular cell of esophagus http://purl.obolibrary.org/obo/CL_0002252 epithelial cell of esophagus A glandular epithelial cell of the esophagus. http://purl.obolibrary.org/obo/GO_0030917 midbrain-hindbrain boundary development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the midbrain-hindbrain boundary over time, from its formation to the mature structure. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. http://purl.obolibrary.org/obo/CL_0002658 glandular cell of the large intestine http://purl.obolibrary.org/obo/CL_0002253 epithelial cell of large intestine A glandular epithelial cell of the large intestine. http://purl.obolibrary.org/obo/CL_0002659 glandular epithelial cell of stomach http://purl.obolibrary.org/obo/CL_0002178 epithelial cell of stomach A glandular epithelial cell that is part of the stomach. http://purl.obolibrary.org/obo/GO_0030955 potassium ion binding http://purl.obolibrary.org/obo/GO_0031420 alkali metal ion binding Binding to a potassium ion (K+). http://purl.obolibrary.org/obo/CL_0002660 luminal cell of acinus of lactiferous gland http://purl.obolibrary.org/obo/CL_0002326 luminal epithelial cell of mammary gland A luminal epithelial cell of mammary gland located in acinus of structure. http://purl.obolibrary.org/obo/GO_0031016 pancreas development http://purl.obolibrary.org/obo/GO_0048513 animal organ development The process whose specific outcome is the progression of the pancreas over time, from its formation to the mature structure. The pancreas is an endoderm derived structure that produces precursors of digestive enzymes and blood glucose regulating hormones. http://purl.obolibrary.org/obo/CL_0002661 luminal cell of lactiferous terminal ductal lobular unit http://purl.obolibrary.org/obo/CL_0002662 luminal cell of lactiferous duct A luminal cell of terminal ducts, i.e.e the terminal branch of a lactiferous duct which alveolar cells drain into. http://purl.obolibrary.org/obo/GO_0031017 exocrine pancreas development http://purl.obolibrary.org/obo/GO_0048732 gland development The process whose specific outcome is the progression of the exocrine pancreas over time, from its formation to the mature structure. The exocrine pancreas produces and store zymogens of digestive enzymes, such as chymotrypsinogen and trypsinogen in the acinar cells. http://purl.obolibrary.org/obo/CL_0002662 luminal cell of lactiferous duct http://purl.obolibrary.org/obo/CL_0020029 cuboidal epithelial cell A luminal epithelial cell of the lactiferous duct. This cuboidal epithelial cell expresses keratin-18 and is estrogen-receptor alpha positive. http://purl.obolibrary.org/obo/GO_0031022 nuclear migration along microfilament http://purl.obolibrary.org/obo/GO_0099515 actin filament-based transport The directed movement of the nucleus along microfilaments within the cell, mediated by motor proteins. http://purl.obolibrary.org/obo/CL_0002663 myocardial endocrine cell of atrium http://purl.obolibrary.org/obo/CL_0002074 myocardial endocrine cell A myocardial endocrine cell that is part of the atrium. http://purl.obolibrary.org/obo/CL_0002664 cardioblast http://purl.obolibrary.org/obo/CL_0000048 multi fate stem cell A stem cell that can give rise to multiple cell types (i.e. smooth muscle, endothelial) in the developing heart. http://purl.obolibrary.org/obo/GO_0031023 microtubule organizing center organization http://purl.obolibrary.org/obo/GO_0007017 microtubule-based process A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microtubule organizing center, a structure from which microtubules grow. http://purl.obolibrary.org/obo/CL_0002665 otic fibrocyte http://purl.obolibrary.org/obo/CL_0008019 mesenchymal cell A mesenchymal cell within the inner ear, specifically localised to supportive connective tissues such as the spiral ligament and spiral limbus. This cell has specialised structural and molecular adaptations, and it contributes to the homeostasis of the cochlear environment by participating in ionic regulation crucial for auditory function. http://purl.obolibrary.org/obo/GO_0031045 dense core granule http://purl.obolibrary.org/obo/GO_0030141 secretory granule Electron-dense organelle with a granular internal matrix; contains proteins destined to be secreted. http://purl.obolibrary.org/obo/GO_0031069 hair follicle morphogenesis http://purl.obolibrary.org/obo/GO_0022405 hair cycle process The process in which the anatomical structures of the hair follicle are generated and organized. http://purl.obolibrary.org/obo/CL_0002666 type II spiral ligament fibrocyte http://purl.obolibrary.org/obo/CL_0020005 spiral ligament fibrocyte A spiral ligament fibrocyte that is located near the spiral prominence between the basilar crest and the stria and plays an important role in potassium recycling by actively pumping K+ from the extracellular space and facilitating transcellular K+ transport through gap junctions toward Type I fibrocytes. In mice, Type II fibrocytes express connexin 26 (Gjb2) and connexin 30 (Gjb6) as part of the mesenchymal gap junction system, as well as the Na‑K‑2Cl cotransporter NKCC1. http://purl.obolibrary.org/obo/GO_0031076 embryonic camera-type eye development http://purl.obolibrary.org/obo/GO_0048568 embryonic organ development The process occurring during the embryonic phase whose specific outcome is the progression of the eye over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0031099 regeneration http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The regrowth of a lost or destroyed body part, such as an organ or tissue. This process may occur via renewal, repair, and/or growth alone (i.e. increase in size or mass). http://purl.obolibrary.org/obo/CL_0002667 type V spiral ligament fibrocyte http://purl.obolibrary.org/obo/CL_0020005 spiral ligament fibrocyte A spiral ligament fibrocyte located in the suprastrial region above the stria vascularis, distinguished from other fibrocytes by their unique expression of COX-1 in guinea pigs and end-foot structures that directly contact capillaries (Dai and Shi, 2011). This fibro-vascular coupling enables type V fibrocytes to regulate cochlear blood flow by translating Ca²⁺ signals into capillary vasodilation via COX-1-derived prostaglandins. This cell also participates in K⁺ recycling, expressing Na,K-ATPase (ATP1A1, ATP1B1) in mice and humans, and connexin 26/30 gap junctions enabling intercellular K⁺ transport within the spiral ligament syncytium (Peeleman et al., 2020). http://purl.obolibrary.org/obo/GO_0031100 animal organ regeneration http://purl.obolibrary.org/obo/GO_0031099 regeneration The regrowth of a lost or destroyed animal organ. http://purl.obolibrary.org/obo/CL_0002668 type IV spiral ligament fibrocyte http://purl.obolibrary.org/obo/CL_0020005 spiral ligament fibrocyte A spiral ligament fibrocyte that is located in the triangular space inferior to the crista basilaris (basilar crest). This cell is spindle-shaped and expresses NKCC1 but minimal to no Na,K-ATPase (ATP1A1, ATP1B1) in mice and humans, and lacks connexin 26/30 in mice, indicating it does not participate in K⁺ recycling, unlike type II fibrocytes. Type IV fibrocyte is uniquely characterised by strong expression of connective tissue growth factor (CTGF) in mice, suggesting roles in tissue remodelling and paracrine signalling to other cochlear cells. http://purl.obolibrary.org/obo/GO_0031110 regulation of microtubule polymerization or depolymerization http://purl.obolibrary.org/obo/GO_0070507 regulation of microtubule cytoskeleton organization Any process that modulates the frequency, rate or extent of microtubule polymerization or depolymerization by the addition or removal of tubulin heterodimers from a microtubule. http://purl.obolibrary.org/obo/GO_0031112 positive regulation of microtubule polymerization or depolymerization http://purl.obolibrary.org/obo/GO_0051495 positive regulation of cytoskeleton organization Any process that activates or increases the frequency, rate or extent of microtubule polymerization or depolymerization. http://purl.obolibrary.org/obo/CL_0002669 type III spiral ligament fibrocyte http://purl.obolibrary.org/obo/CL_0020005 spiral ligament fibrocyte A spiral ligament fibrocyte that is located in the deepest part of the inferior spiral ligament, directly lining the bony otic capsule. Distinguished from ion-transporting Type I and II fibrocytes, it utilises actin-myosin stress fibres and anchoring interactions to regulate basilar membrane tension. It has an elongated morphology, is most numerous in the basal, high-frequency cochlea, and expresses contractile and cytoskeletal proteins in mice, including α‑smooth muscle actin, non‑muscle myosin II, caldesmon, and the water channel Aquaporin‑1(Mahendrasingam et al., 2011; Kelly et al., 2012). http://purl.obolibrary.org/obo/GO_0031115 negative regulation of microtubule polymerization http://purl.obolibrary.org/obo/GO_0031113 regulation of microtubule polymerization Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule polymerization. http://purl.obolibrary.org/obo/GO_0031116 positive regulation of microtubule polymerization http://purl.obolibrary.org/obo/GO_0031113 regulation of microtubule polymerization Any process that activates or increases the frequency, rate or extent of microtubule polymerization. http://purl.obolibrary.org/obo/CL_0002670 type I spiral ligament fibrocyte http://purl.obolibrary.org/obo/CL_0020005 spiral ligament fibrocyte A spiral ligament fibrocyte that underlies the stria vascularis and is part of a mesenchymal gap junction network that regulates ionic homeostasis of the endolymph. In mice, expression of connexin 26 (Gjb2) and connexin 30 (Gjb6) serves as a distinguishing molecular signature. http://purl.obolibrary.org/obo/GO_0031117 positive regulation of microtubule depolymerization http://purl.obolibrary.org/obo/GO_1902905 positive regulation of supramolecular fiber organization Any process that activates or increases the frequency, rate or extent of microtubule depolymerization. http://purl.obolibrary.org/obo/GO_0031143 pseudopodium http://purl.obolibrary.org/obo/GO_0120025 plasma membrane bounded cell projection A temporary protrusion or retractile process of a cell, associated with flowing movements of the protoplasm, and serving for locomotion and feeding. http://purl.obolibrary.org/obo/CL_0002671 endothelial stalk cell http://purl.obolibrary.org/obo/CL_0000071 blood vessel endothelial cell An endothelial stalk cell is a specialized endothelial cell that follows behind the tip cell of an angiogenic sprout. http://purl.obolibrary.org/obo/GO_0031201 SNARE complex http://purl.obolibrary.org/obo/GO_0098796 membrane protein complex A protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers. One well-characterized example is the neuronal SNARE complex formed of synaptobrevin 2, syntaxin 1a, and SNAP-25. http://purl.obolibrary.org/obo/GO_0031214 biomineral tissue development http://purl.obolibrary.org/obo/GO_0009888 tissue development Formation of hard tissues that consist mainly of inorganic compounds, and also contain a small amounts of organic matrices that are believed to play important roles in their formation. http://purl.obolibrary.org/obo/CL_0002672 retinal progenitor cell http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell A multi-fate stem cell that can give rise to different retinal cell types including rod and cone cells. http://purl.obolibrary.org/obo/GO_0031253 cell projection membrane http://purl.obolibrary.org/obo/GO_0098590 plasma membrane region The portion of the plasma membrane surrounding a plasma membrane bounded cell surface projection. http://purl.obolibrary.org/obo/GO_0031256 leading edge membrane http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure The portion of the plasma membrane surrounding the leading edge of a motile cell. http://purl.obolibrary.org/obo/CL_0002673 tongue muscle cell http://purl.obolibrary.org/obo/CL_0008002 skeletal muscle fiber A skeletal muscle cell that is part of the tongue. http://purl.obolibrary.org/obo/GO_0031268 pseudopodium organization http://purl.obolibrary.org/obo/GO_0120036 plasma membrane bounded cell projection organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a pseudopodium, a temporary protrusion or retractile process of a cell, associated with cellular movement. http://purl.obolibrary.org/obo/CL_0002674 H minus http://purl.obolibrary.org/obo/CL_0000521 fungal cell A S. pombe mating type determined by the mat1-Mc and mat1-Mi on the mat1 locus. http://purl.obolibrary.org/obo/GO_0031269 pseudopodium assembly http://purl.obolibrary.org/obo/GO_0120031 plasma membrane bounded cell projection assembly The assembly of a pseudopodium by rearrangement of the actin cytoskeleton and overlying membrane. http://purl.obolibrary.org/obo/CL_0002675 H plus http://purl.obolibrary.org/obo/CL_0000521 fungal cell A S. pombe cell type determined by mat1-Pc and mat1-Pi on the mat1 locus. http://purl.obolibrary.org/obo/GO_0031270 pseudopodium retraction http://purl.obolibrary.org/obo/GO_0031268 pseudopodium organization The myosin-based contraction and retraction of a pseudopodium. http://purl.obolibrary.org/obo/CL_0002676 neural crest derived neuroblast http://purl.obolibrary.org/obo/CL_0000031 neuroblast (sensu Vertebrata) A neuroblast derived from a neural crest cell. http://purl.obolibrary.org/obo/CL_0002677 naive regulatory T cell http://purl.obolibrary.org/obo/CL_0000898 naive T cell A regulatory T cell that has not encountered antigen. http://purl.obolibrary.org/obo/GO_0031272 regulation of pseudopodium assembly http://purl.obolibrary.org/obo/GO_0120032 regulation of plasma membrane bounded cell projection assembly Any process that modulates the frequency, rate or extent of the assembly of pseudopodia. http://purl.obolibrary.org/obo/CL_0002678 memory regulatory T cell http://purl.obolibrary.org/obo/CL_0000897 CD4-positive, alpha-beta memory T cell A CD4-positive, CD25-positive alpha-beta regulatory T cell that has encountered antigen. http://purl.obolibrary.org/obo/GO_0031273 negative regulation of pseudopodium assembly http://purl.obolibrary.org/obo/GO_0120033 negative regulation of plasma membrane bounded cell projection assembly Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of pseudopodia. http://purl.obolibrary.org/obo/CL_0002679 natural helper lymphocyte http://purl.obolibrary.org/obo/CL_0000542 lymphocyte A lymphocyte found in adipose tissue that lacks lineage markers of other lymphocytes but is capable of mediating TH2 cytokine responses. This cell type is found in fat associated lymphoid clusters, proliferates in response to IL2 and produce large amounts of TH2 cytokines such as IL5, IL6 and IL13 http://purl.obolibrary.org/obo/GO_0031274 positive regulation of pseudopodium assembly http://purl.obolibrary.org/obo/GO_0120034 positive regulation of plasma membrane bounded cell projection assembly Any process that activates or increases the frequency, rate or extent of the assembly of pseudopodia. http://purl.obolibrary.org/obo/CL_0002680 PP cell of intestine http://purl.obolibrary.org/obo/CL_1001516 intestinal enteroendocrine cell A PP cell found in intestine. http://purl.obolibrary.org/obo/GO_0031294 lymphocyte costimulation http://purl.obolibrary.org/obo/GO_0051251 positive regulation of lymphocyte activation The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the B- or T cell receptor to augment B- or T cell activation. http://purl.obolibrary.org/obo/CL_0002681 kidney cortical cell http://purl.obolibrary.org/obo/CL_1000497 kidney cell A cell that is part of a cortex of kidney. http://purl.obolibrary.org/obo/GO_0031295 T cell costimulation http://purl.obolibrary.org/obo/GO_0050870 positive regulation of T cell activation The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the T cell receptor to augment T cell activation. http://purl.obolibrary.org/obo/CL_0005000 spinal cord interneuron http://purl.obolibrary.org/obo/CL_0000099 interneuron A CNS interneuron located in the spinal cord. http://purl.obolibrary.org/obo/GO_0031296 B cell costimulation http://purl.obolibrary.org/obo/GO_0050871 positive regulation of B cell activation The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the B cell receptor to augment B cell activation. http://purl.obolibrary.org/obo/CL_0005001 iridoblast http://purl.obolibrary.org/obo/CL_0011026 progenitor cell A non-terminally differentiated cell that originates from the neural crest and differentiates into an iridophore. http://purl.obolibrary.org/obo/GO_0031338 regulation of vesicle fusion http://purl.obolibrary.org/obo/GO_0060627 regulation of vesicle-mediated transport Any process that modulates the frequency, rate or extent of vesicle fusion. http://purl.obolibrary.org/obo/CL_0005002 xanthoblast http://purl.obolibrary.org/obo/CL_0011026 progenitor cell A non-terminally differentiated cell that differentiates into a xanthophore. http://purl.obolibrary.org/obo/GO_0031339 negative regulation of vesicle fusion http://purl.obolibrary.org/obo/GO_0051051 negative regulation of transport Any process that stops, prevents, or reduces the frequency, rate or extent of vesicle fusion. http://purl.obolibrary.org/obo/CL_0005003 leucoblast http://purl.obolibrary.org/obo/CL_0011026 progenitor cell A non-terminally differentiated cell that originates from the neural crest and differentiates into a leucophore. http://purl.obolibrary.org/obo/GO_0031340 positive regulation of vesicle fusion http://purl.obolibrary.org/obo/GO_0051050 positive regulation of transport Any process that activates or increases the frequency, rate or extent of vesicle fusion. http://purl.obolibrary.org/obo/CL_0005004 pigment erythroblast http://purl.obolibrary.org/obo/CL_0011026 progenitor cell A non-terminally differentiated cell that originates from the neural crest and differentiates into an erythrophore. http://purl.obolibrary.org/obo/GO_0031402 sodium ion binding http://purl.obolibrary.org/obo/GO_0031420 alkali metal ion binding Binding to a sodium ion (Na+). http://purl.obolibrary.org/obo/CL_0005005 cyanoblast http://purl.obolibrary.org/obo/CL_0011026 progenitor cell A non-terminally differentiated cell that originates from the neural crest and differentiates into a cyanophore. http://purl.obolibrary.org/obo/GO_0031409 pigment binding http://purl.obolibrary.org/obo/GO_0005488 binding Binding to a pigment, a general or particular coloring matter in living organisms, e.g. melanin. http://purl.obolibrary.org/obo/CL_0005006 ionocyte http://purl.obolibrary.org/obo/CL_0000066 epithelial cell Specialized epithelial cells involved in the maintenance of osmotic homeostasis. They are characterized by abundant mitochondria and ion transporters. In amniotes, they are present in the renal system. In freshwater fish, ionocytes in the skin and gills help maintain osmotic homeostasis by absorbing salt from the external environment. http://purl.obolibrary.org/obo/GO_0031420 alkali metal ion binding http://purl.obolibrary.org/obo/GO_0046872 metal ion binding Binding to an alkali metal ion; alkali metals are those elements in group Ia of the periodic table, with the exception of hydrogen. http://purl.obolibrary.org/obo/CL_0005007 Kolmer-Agduhr neuron http://purl.obolibrary.org/obo/CL_0011005 GABAergic interneuron Kolmer-Agduhr neurons are ciliated GABAergic neurons that contact the central canal of the spinal cord and have ipsilateral ascending axons. http://purl.obolibrary.org/obo/GO_0031424 keratinization http://purl.obolibrary.org/obo/GO_0032501 multicellular organismal process The process in which the cytoplasm of the outermost cells of the vertebrate epidermis is replaced by keratin. Keratinization occurs in the stratum corneum, feathers, hair, claws, nails, hooves, and horns. http://purl.obolibrary.org/obo/CL_0005008 macular hair cell http://purl.obolibrary.org/obo/CL_0002374 ear hair cell An auditory hair cell located in the macula that is sensitive to auditory stimuli. http://purl.obolibrary.org/obo/GO_0031445 regulation of heterochromatin formation http://purl.obolibrary.org/obo/GO_0010468 regulation of gene expression Any process that modulates the frequency, rate, extent or location of heterochromatin formation. http://purl.obolibrary.org/obo/CL_0005009 renal principal cell http://purl.obolibrary.org/obo/CL_0002518 kidney epithelial cell A cuboidal epithelial cell of the kidney which regulates sodium and potassium balance. The activity of sodium and potassium channels on the apical membrane of the cell is regulated by aldosterone and vasopressin. In mammals this cell type is located in the renal collecting duct system. http://purl.obolibrary.org/obo/GO_0031452 negative regulation of heterochromatin formation http://purl.obolibrary.org/obo/GO_0010628 positive regulation of gene expression Any process that stops, prevents, or reduces the frequency, rate or extent of heterochromatin formation. http://purl.obolibrary.org/obo/GO_0031453 positive regulation of heterochromatin formation http://purl.obolibrary.org/obo/GO_0044089 positive regulation of cellular component biogenesis Any process that activates or increases the frequency, rate or extent of heterochromatin formation. http://purl.obolibrary.org/obo/CL_0005010 renal intercalated cell http://purl.obolibrary.org/obo/CL_1000449 epithelial cell of nephron A cuboidal epithelial cell of the kidney that regulates acid/base balance. http://purl.obolibrary.org/obo/GO_0031503 protein-containing complex localization http://purl.obolibrary.org/obo/GO_0033036 macromolecule localization A localization process that acts on a protein complex; the complex is transported to, or maintained in, a specific location. http://purl.obolibrary.org/obo/CL_0005011 renal alpha-intercalated cell http://purl.obolibrary.org/obo/CL_0005010 renal intercalated cell A cuboidal epithelial cell of the kidney which secretes acid and reabsorbs base to regulate acid/base balance. http://purl.obolibrary.org/obo/CL_0005012 multiciliated epithelial cell http://purl.obolibrary.org/obo/CL_0000075 columnar/cuboidal epithelial cell A columnar/cuboidal epithelial cell with multiple motile cilia on its apical surface. These cells facilitate the movement of liquids such as mucus or cerebrospinal fluid across the epithelial surface. http://purl.obolibrary.org/obo/GO_0031507 heterochromatin formation http://purl.obolibrary.org/obo/GO_0070828 heterochromatin organization An epigenetic gene silencing mechanism in which chromatin is compacted into heterochromatin, resulting in a chromatin conformation refractory to transcription. This process starts with heterochromatin nucleation, its spreading, and ends with heterochromatin boundary formation. http://purl.obolibrary.org/obo/CL_0005013 single ciliated epithelial cell http://purl.obolibrary.org/obo/CL_0000067 ciliated epithelial cell A ciliated epithelial cell with a single cilium. http://purl.obolibrary.org/obo/GO_0031594 neuromuscular junction http://purl.obolibrary.org/obo/GO_0045202 synapse The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a change in post-synaptic potential. http://purl.obolibrary.org/obo/CL_0005014 auditory epithelial supporting cell http://purl.obolibrary.org/obo/CL_0002491 auditory epithelial cell A non-sensory cell that extends from the basement membrane to the apical surface of the auditory epithelium and provides support for auditory hair cells. http://purl.obolibrary.org/obo/CL_0005015 inner phalangeal cell http://purl.obolibrary.org/obo/CL_0002165 phalangeal cell An auditory epithelial support cell that surrounds the nerve fibers and synapses of the auditory inner hair cells. http://purl.obolibrary.org/obo/GO_0031641 regulation of myelination http://purl.obolibrary.org/obo/GO_0051960 regulation of nervous system development Any process that modulates the frequency, rate or extent of the formation of a myelin sheath around nerve axons. http://purl.obolibrary.org/obo/CL_0005018 ghrelin secreting cell http://purl.obolibrary.org/obo/CL_0000167 peptide hormone secreting cell A cell that secretes ghrelin, the peptide hormone that stimulates hunger. http://purl.obolibrary.org/obo/GO_0031642 negative regulation of myelination http://purl.obolibrary.org/obo/GO_0031645 negative regulation of nervous system process Any process that stops, prevents, or reduces the frequency, rate or extent of the formation of a myelin sheath around nerve axons. http://purl.obolibrary.org/obo/CL_0005019 pancreatic epsilon cell http://purl.obolibrary.org/obo/CL_0008024 pancreatic endocrine cell Ghrelin secreting cells found in the endocrine pancreas. http://purl.obolibrary.org/obo/GO_0031643 positive regulation of myelination http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the frequency, rate or extent of the formation of a myelin sheath around nerve axons. http://purl.obolibrary.org/obo/CL_0005020 lymphangioblast http://purl.obolibrary.org/obo/CL_4033054 perivascular cell Lymphatic progenitor cells. http://purl.obolibrary.org/obo/GO_0031644 regulation of nervous system process http://purl.obolibrary.org/obo/GO_0044057 regulation of system process Any process that modulates the frequency, rate or extent of a neurophysiological process, an organ system process carried out by any of the organs or tissues of the nervous system. http://purl.obolibrary.org/obo/CL_0005021 mesenchymal lymphangioblast http://purl.obolibrary.org/obo/CL_0005020 lymphangioblast Mesenchymal derived lymphatic progenitor cells that give rise to the superficial lymphatics. http://purl.obolibrary.org/obo/GO_0031645 negative regulation of nervous system process http://purl.obolibrary.org/obo/GO_0031644 regulation of nervous system process Any process that stops, prevents, or reduces the frequency, rate or extent of a neurophysiological process. http://purl.obolibrary.org/obo/CL_0005022 vascular lymphangioblast http://purl.obolibrary.org/obo/CL_0005020 lymphangioblast Lymphatic progenitor cells, derived from the veins, that give rise to lymphatic endothelial cells. http://purl.obolibrary.org/obo/GO_0031646 positive regulation of nervous system process http://purl.obolibrary.org/obo/GO_0031644 regulation of nervous system process Any process that activates or increases the frequency, rate or extent of a neurophysiological process. http://purl.obolibrary.org/obo/CL_0005023 branchiomotor neuron http://purl.obolibrary.org/obo/CL_0015000 cranial motor neuron Cranial motor neuron which innervates muscles derived from the branchial (pharyngeal) arches. http://purl.obolibrary.org/obo/GO_0031723 CXCR4 chemokine receptor binding http://purl.obolibrary.org/obo/GO_0045236 CXCR chemokine receptor binding Binding to a CXCR4 chemokine receptor. http://purl.obolibrary.org/obo/CL_0005024 somatomotor neuron http://purl.obolibrary.org/obo/CL_0000108 cholinergic neuron A motor neuron that innervates a skeletal muscle. These motor neurons are all excitatory and cholinergic. http://purl.obolibrary.org/obo/GO_0031727 CCR2 chemokine receptor binding http://purl.obolibrary.org/obo/GO_0048020 CCR chemokine receptor binding Binding to a CCR2 chemokine receptor. http://purl.obolibrary.org/obo/CL_0005025 visceromotor neuron http://purl.obolibrary.org/obo/CL_0000100 motor neuron A motor neuron that synapses to parasympathetic neurons that innervate tear glands, sweat glands, and the smooth muscles and glands of the pulmonary, cardiovascular, and gastrointestinal systems. http://purl.obolibrary.org/obo/GO_0031728 CCR3 chemokine receptor binding http://purl.obolibrary.org/obo/GO_0048020 CCR chemokine receptor binding Binding to a CCR3 chemokine receptor. http://purl.obolibrary.org/obo/CL_0005026 hepatoblast http://purl.obolibrary.org/obo/CL_0000048 multi fate stem cell Multi fate stem cell that gives rise to both hepatocytes and cholangiocytes as descendants. The term often refers to fetal precursors of hepatocytes (differently from 'hepatic stem cell', usually applied to the self-renewing pool of hepatocyte precursors in the adult liver). Hepatoblasts may also be endogenous, as some stem cells found in the liver come from the bone marrow via blood circulation. http://purl.obolibrary.org/obo/GO_0031731 CCR6 chemokine receptor binding http://purl.obolibrary.org/obo/GO_0048020 CCR chemokine receptor binding Binding to a CCR6 chemokine receptor. http://purl.obolibrary.org/obo/GO_0031732 CCR7 chemokine receptor binding http://purl.obolibrary.org/obo/GO_0048020 CCR chemokine receptor binding Binding to a CCR7 chemokine receptor. http://purl.obolibrary.org/obo/CL_0007000 preameloblast http://purl.obolibrary.org/obo/CL_0011026 progenitor cell Skeletogenic cell that has the potential to develop into an ameloblast. Located in the inner enamel epithelium, these cells elongate, their nuclei shift distally (away from the dental papilla), and their cytoplasm becomes filled with organelles needed for synthesis and secretion of enamel proteins. http://purl.obolibrary.org/obo/GO_0031737 CX3C chemokine receptor binding http://purl.obolibrary.org/obo/GO_0042379 chemokine receptor binding Binding to a CX3C chemokine receptor. http://purl.obolibrary.org/obo/GO_0031761 fMet-Leu-Phe receptor binding http://purl.obolibrary.org/obo/GO_0001664 G protein-coupled receptor binding Binding to a fMet-Leu-Phe receptor. http://purl.obolibrary.org/obo/CL_0007001 skeletogenic cell http://purl.obolibrary.org/obo/CL_0000000 cell Cell that has the potential to form a skeletal cell type (e.g. cells in periosteum, cells in marrow) and produce extracellular matrix (often mineralized) and skeletal tissue (often mineralized). http://purl.obolibrary.org/obo/GO_0031855 oxytocin receptor binding http://purl.obolibrary.org/obo/GO_0001664 G protein-coupled receptor binding Binding to an oxytocin receptor. http://purl.obolibrary.org/obo/CL_0007002 precementoblast http://purl.obolibrary.org/obo/CL_0011026 progenitor cell Skeletogenic cell that has the potential to develop into a cementoblast. http://purl.obolibrary.org/obo/GO_0031862 prostanoid receptor binding http://purl.obolibrary.org/obo/GO_0001664 G protein-coupled receptor binding Binding to a prostanoid receptor. http://purl.obolibrary.org/obo/CL_0007003 preodontoblast http://purl.obolibrary.org/obo/CL_0011026 progenitor cell Skeletogenic cell that has the potential to form an odontoblast, deposits predentine, and arises from a cranial neural crest cell. http://purl.obolibrary.org/obo/GO_0031943 regulation of glucocorticoid metabolic process http://purl.obolibrary.org/obo/GO_0032350 regulation of hormone metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving glucocorticoids. http://purl.obolibrary.org/obo/CL_0007004 premigratory neural crest cell http://purl.obolibrary.org/obo/CL_0011012 neural crest cell Cell that is part of the neural crest region of the neuroepithelium, prior to migration. Note that not all premigratory neural crest cells may become migratory neural crest cells. http://purl.obolibrary.org/obo/GO_0031946 regulation of glucocorticoid biosynthetic process http://purl.obolibrary.org/obo/GO_0031943 regulation of glucocorticoid metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucocorticoids. http://purl.obolibrary.org/obo/CL_0007005 notochordal cell http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell Cell that is part of the notochord. http://purl.obolibrary.org/obo/GO_0031947 negative regulation of glucocorticoid biosynthetic process http://purl.obolibrary.org/obo/GO_0090032 negative regulation of steroid hormone biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucocorticoids. http://purl.obolibrary.org/obo/CL_0007006 chordamesodermal cell http://purl.obolibrary.org/obo/CL_0000222 mesodermal cell Mesodermal cell that is axially located and gives rise to the cells of the notochord. http://purl.obolibrary.org/obo/GO_0031948 positive regulation of glucocorticoid biosynthetic process http://purl.obolibrary.org/obo/GO_0090031 positive regulation of steroid hormone biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucocorticoids. http://purl.obolibrary.org/obo/CL_0007007 notochordal sheath cell http://purl.obolibrary.org/obo/CL_0007005 notochordal cell Notochordal cell that is part of the outer epithelium of the notochord and surrounds the vacuolated notochord cells. http://purl.obolibrary.org/obo/GO_0031949 regulation of glucocorticoid catabolic process http://purl.obolibrary.org/obo/GO_0050994 regulation of lipid catabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glucocorticoids. http://purl.obolibrary.org/obo/CL_0007008 notochordal vacuole cell http://purl.obolibrary.org/obo/CL_0007005 notochordal cell Notochordal cell that is inner portion of the notochord and becomes vacuolated as development proceeds. http://purl.obolibrary.org/obo/CL_0007009 prechondroblast http://purl.obolibrary.org/obo/CL_0011026 progenitor cell Skeletogenic cell that has the potential to develop into a chondroblast; and arises from neural crest, meseosdermal and notochordal and connective tissue cells. http://purl.obolibrary.org/obo/GO_0031950 negative regulation of glucocorticoid catabolic process http://purl.obolibrary.org/obo/GO_0050995 negative regulation of lipid catabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glucocorticoids. http://purl.obolibrary.org/obo/CL_0007010 preosteoblast http://purl.obolibrary.org/obo/CL_0011026 progenitor cell Skeletogenic cell that has the potential to transform into an osteoblast, and develops from neural crest or mesodermal cells. http://purl.obolibrary.org/obo/GO_0031951 positive regulation of glucocorticoid catabolic process http://purl.obolibrary.org/obo/GO_0050996 positive regulation of lipid catabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glucocorticoids. http://purl.obolibrary.org/obo/CL_0007011 enteric neuron http://purl.obolibrary.org/obo/CL_0000107 autonomic neuron Neuron that is part of the enteric nervous system. http://purl.obolibrary.org/obo/GO_0031960 response to corticosteroid http://purl.obolibrary.org/obo/GO_0048545 response to steroid hormone Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosteroid hormone stimulus. A corticosteroid is a steroid hormone that is produced in the adrenal cortex. Corticosteroids are involved in a wide range of physiologic systems such as stress response, immune response and regulation of inflammation, carbohydrate metabolism, protein catabolism, blood electrolyte levels, and behavior. They include glucocorticoids and mineralocorticoids. http://purl.obolibrary.org/obo/CL_0007012 non-terminally differentiated odontoblast http://purl.obolibrary.org/obo/CL_0011026 progenitor cell Odontoblast that non-terminally differentiated, located in the odontogenic papilla and dentine tissue, and transforms from a odontoblast cell. http://purl.obolibrary.org/obo/CL_0007013 terminally differentiated odontoblast http://purl.obolibrary.org/obo/CL_0000060 odontoblast Odontoblast that is terminally differentiated and derived from an odontogenic papilla and associated with dentine. http://purl.obolibrary.org/obo/GO_0031987 locomotion involved in locomotory behavior http://purl.obolibrary.org/obo/GO_0040011 locomotion Self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement. http://purl.obolibrary.org/obo/CL_0007016 adaxial cell http://purl.obolibrary.org/obo/CL_0000680 muscle precursor cell Muscle precursor cell that is adjacent to the notochord and part of the presomitic mesoderm. http://purl.obolibrary.org/obo/CL_0007017 Stiftchenzellen http://purl.obolibrary.org/obo/CL_0000206 chemoreceptor cell An epidermal cell with apical microvilli or a single apical projection have synaptic associations with nerve fibres in the epidermis. http://purl.obolibrary.org/obo/GO_0032024 positive regulation of insulin secretion http://purl.obolibrary.org/obo/GO_0090277 positive regulation of peptide hormone secretion Any process that activates or increases the frequency, rate or extent of the regulated release of insulin. http://purl.obolibrary.org/obo/CL_0007018 epidermal ciliary cell http://purl.obolibrary.org/obo/CL_0002321 embryonic cell (metazoa) Ciliated cell of the embryonic epidermis and functions in embryonic movements. http://purl.obolibrary.org/obo/GO_0032043 mitochondrial DNA catabolic process http://purl.obolibrary.org/obo/GO_0006308 DNA catabolic process The chemical reactions and pathways resulting in the breakdown of mitochondrial DNA. http://purl.obolibrary.org/obo/GO_0032052 bile acid binding http://purl.obolibrary.org/obo/GO_0033293 monocarboxylic acid binding Binding to a bile acid, a steroid carboxylic acids occurring in bile. http://purl.obolibrary.org/obo/CL_0007020 bottle cell http://purl.obolibrary.org/obo/CL_0000007 early embryonic cell (metazoa) Characteristic early embryonic cell with a bottle or flask shape that is first to migrate inwards at the blastopore during gastrulation in amphibians. http://purl.obolibrary.org/obo/GO_0032053 ciliary basal body organization http://purl.obolibrary.org/obo/GO_0044782 cilium organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a ciliary basal body, a short cylindrical array of microtubules and associated proteins found at the base of a eukaryotic cilium (also called flagellum). http://purl.obolibrary.org/obo/CL_0007021 alarm substance cell http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell Secretory cell that produces a chemical mixture that triggers antipredator behavior. The substance is released only upon disruption of the epidermis. [Behavior of teleost fishes, second edition, edited by Pitcher, 1992] http://purl.obolibrary.org/obo/CL_0007022 micropylar cell http://purl.obolibrary.org/obo/CL_0002174 follicular cell of ovary A specialized pore forming cell of the follicle, located adjacent to the animal pole of the oocyte. The micropylar cell makes the single micropyle (pore) through the chorion through which the sperm fertilizes the egg. http://purl.obolibrary.org/obo/GO_0032055 negative regulation of translation in response to stress http://purl.obolibrary.org/obo/GO_0043555 regulation of translation in response to stress Any process that stops, prevents or reduces the rate of translation as a result of a stimulus indicating the organism is under stress. http://purl.obolibrary.org/obo/GO_0032057 negative regulation of translational initiation in response to stress http://purl.obolibrary.org/obo/GO_0045947 negative regulation of translational initiation Any process that stops, prevents or reduces the rate of translation initiation as a result of a stimulus indicating the organism is under stress. http://purl.obolibrary.org/obo/CL_0007023 flask cell http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell Epidermal cell rich in mitochondria. In amphibians, appears during metamorphosis. http://purl.obolibrary.org/obo/CL_0008000 non-striated muscle cell http://purl.obolibrary.org/obo/CL_0000187 muscle cell Any muscle cell in which the fibers are not organised into sarcomeres. http://purl.obolibrary.org/obo/GO_0032058 positive regulation of translational initiation in response to stress http://purl.obolibrary.org/obo/GO_0045948 positive regulation of translational initiation Any process that activates or increases the frequency, rate or extent of translation initiation as a result of a stimulus indicating the organism is under stress. http://purl.obolibrary.org/obo/CL_0008001 hematopoietic precursor cell http://purl.obolibrary.org/obo/CL_0000988 hematopoietic cell Any hematopoietic cell that is a precursor of some other hematopoietic cell type. http://purl.obolibrary.org/obo/GO_0032059 bleb http://purl.obolibrary.org/obo/GO_0120025 plasma membrane bounded cell projection A cell extension caused by localized decoupling of the cytoskeleton from the plasma membrane and characterized by rapid formation, rounded shape, and scarcity of organelles within the protrusion. Blebs are formed during apoptosis and other cellular processes, including cell locomotion, cell division, and as a result of physical or chemical stresses. http://purl.obolibrary.org/obo/CL_0008002 skeletal muscle fiber http://purl.obolibrary.org/obo/CL_0002372 myotube A transversely striated, synctial cell of skeletal muscle. It is formed when proliferating myoblasts exit the cell cycle, differentiate and fuse. http://purl.obolibrary.org/obo/CL_0008003 somatic muscle myotube http://purl.obolibrary.org/obo/CL_0008004 somatic muscle cell A myotube that is part of some somatic muscle. Examples include arthropod somatic muscle cells. http://purl.obolibrary.org/obo/GO_0032060 bleb assembly http://purl.obolibrary.org/obo/GO_0120031 plasma membrane bounded cell projection assembly The assembly of a bleb, a cell extension caused by localized decoupling of the cytoskeleton from the plasma membrane and characterized by rapid formation, rounded shape, and scarcity of organelles within the protrusion. Plasma membrane blebbing occurs during apoptosis and other cellular processes, including cell locomotion, cell division, and as a result of physical or chemical stresses. http://purl.obolibrary.org/obo/CL_0008004 somatic muscle cell http://purl.obolibrary.org/obo/CL_0000187 muscle cell A muscle cell that is part of some somatic muscle. http://purl.obolibrary.org/obo/GO_0032065 maintenance of protein location in cell cortex http://purl.obolibrary.org/obo/GO_0032507 maintenance of protein location in cell A process in which a protein or protein complex is maintained in a specific location in the cell cortex. http://purl.obolibrary.org/obo/CL_0008005 obliquely striated somatic muscle cell http://purl.obolibrary.org/obo/CL_0008004 somatic muscle cell A somatic muscle cell that is obliquely striated and mononucleated. Examples include the somatic muscles of nematodes. http://purl.obolibrary.org/obo/CL_0008006 muscle founder cell http://purl.obolibrary.org/obo/CL_0008018 somatic muscle myoblast A myoblast that detemines the properties (size, shape and attachment to the epidermis) of a `somatic muscle myotube` (CL:0008003) . It develops into a somatic muscle myotube via fusion with `fusion component myoblasts` (CL:0000621). http://purl.obolibrary.org/obo/GO_0032077 positive regulation of deoxyribonuclease activity http://purl.obolibrary.org/obo/GO_0051054 positive regulation of DNA metabolic process Any process that activates or increases the frequency, rate or extent of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid. http://purl.obolibrary.org/obo/GO_0032092 positive regulation of protein binding http://purl.obolibrary.org/obo/GO_0051099 positive regulation of binding Any process that activates or increases the frequency, rate or extent of protein binding. http://purl.obolibrary.org/obo/CL_0008007 visceral muscle cell http://purl.obolibrary.org/obo/CL_0000187 muscle cell A muscle cell that is part of some visceral muscle. http://purl.obolibrary.org/obo/CL_0008008 striated visceral muscle cell http://purl.obolibrary.org/obo/CL_0008007 visceral muscle cell A visceral muscle cell that is striated. Examples include the visceral muscle cells of arhtropods. http://purl.obolibrary.org/obo/GO_0032127 dense core granule membrane http://purl.obolibrary.org/obo/GO_0030667 secretory granule membrane The lipid bilayer surrounding a dense core granule. http://purl.obolibrary.org/obo/CL_0008009 transversely striated visceral muscle cell http://purl.obolibrary.org/obo/CL_0008008 striated visceral muscle cell A visceral muscle that is transversely striated. Examples include the visceral muscle cells of arthropods. http://purl.obolibrary.org/obo/GO_0032225 regulation of synaptic transmission, dopaminergic http://purl.obolibrary.org/obo/GO_0050804 modulation of chemical synaptic transmission Any process that modulates the frequency, rate or extent of dopaminergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter dopamine. http://purl.obolibrary.org/obo/CL_0008010 cranial somatomotor neuron http://purl.obolibrary.org/obo/CL_0015000 cranial motor neuron A cranial motor neuron whose soma is located in the midbrain andor hindbrain and which innervates the skeletal muscles of the eye or tongue. http://purl.obolibrary.org/obo/GO_0032226 positive regulation of synaptic transmission, dopaminergic http://purl.obolibrary.org/obo/GO_0032225 regulation of synaptic transmission, dopaminergic Any process that activates, maintains or increases the frequency, rate or extent of dopaminergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter dopamine. http://purl.obolibrary.org/obo/CL_0008013 cranial visceromotor neuron http://purl.obolibrary.org/obo/CL_2000029 central nervous system neuron A visceromotor motor neuron whose soma is located in the hindbrain, and which synapses to parasympathetic neurons that innervate tear glands, sweat glands, and the smooth muscles of the head. http://purl.obolibrary.org/obo/GO_0032227 negative regulation of synaptic transmission, dopaminergic http://purl.obolibrary.org/obo/GO_0050805 negative regulation of synaptic transmission Any process that stops, prevents, or reduces the frequency, rate or extent of dopaminergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter dopamine. http://purl.obolibrary.org/obo/CL_0008015 inhibitory motor neuron http://purl.obolibrary.org/obo/CL_0000100 motor neuron A motor neuron that is capable of directly inhibiting muscle contraction. http://purl.obolibrary.org/obo/GO_0032228 regulation of synaptic transmission, GABAergic http://purl.obolibrary.org/obo/GO_0050804 modulation of chemical synaptic transmission Any process that modulates the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA). http://purl.obolibrary.org/obo/CL_0009000 sensory neuron of spinal nerve http://purl.obolibrary.org/obo/CL_3000004 peripheral sensory neuron A sensory neuron of the spinal nerve that senses body position and sends information about how much the muscle is stretched to the spinal cord. http://purl.obolibrary.org/obo/GO_0032229 negative regulation of synaptic transmission, GABAergic http://purl.obolibrary.org/obo/GO_0050805 negative regulation of synaptic transmission Any process that stops, prevents, or reduces the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA). http://purl.obolibrary.org/obo/CL_0009001 compound eye retinal cell http://purl.obolibrary.org/obo/CL_0009004 retinal cell Any cell in the compound eye, a light sensing organ composed of ommatidia. http://purl.obolibrary.org/obo/CL_0009002 inflammatory cell http://purl.obolibrary.org/obo/CL_0000000 cell Any cell participating in the inflammatory response to a foreign substance, e.g. neutrophil, macrophage. http://purl.obolibrary.org/obo/GO_0032230 positive regulation of synaptic transmission, GABAergic http://purl.obolibrary.org/obo/GO_0032228 regulation of synaptic transmission, GABAergic Any process that activates, maintains or increases the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA). http://purl.obolibrary.org/obo/CL_0009003 larval midgut cell http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell Any cell in the midgut (middle subdivision of a digestive tract) of an insect larva. http://purl.obolibrary.org/obo/CL_0009004 retinal cell http://purl.obolibrary.org/obo/CL_0002319 neural cell Any cell in the retina, the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates. http://purl.obolibrary.org/obo/GO_0032231 regulation of actin filament bundle assembly http://purl.obolibrary.org/obo/GO_0110053 regulation of actin filament organization Any process that modulates the frequency, rate or extent of the assembly of actin filament bundles. http://purl.obolibrary.org/obo/CL_0009005 salivary gland cell http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell Any cell in a salivary gland. http://purl.obolibrary.org/obo/GO_0032232 negative regulation of actin filament bundle assembly http://purl.obolibrary.org/obo/GO_0051494 negative regulation of cytoskeleton organization Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of actin filament bundles. http://purl.obolibrary.org/obo/CL_0010001 stromal cell of bone marrow http://purl.obolibrary.org/obo/CL_0002092 bone marrow cell A stromal cell that is part_of a bone marrow. http://purl.obolibrary.org/obo/GO_0032233 positive regulation of actin filament bundle assembly http://purl.obolibrary.org/obo/GO_0051495 positive regulation of cytoskeleton organization Any process that activates or increases the frequency, rate or extent of the assembly of actin filament bundles. http://purl.obolibrary.org/obo/CL_0010002 epithelial cell of umbilical artery http://purl.obolibrary.org/obo/CL_0000066 epithelial cell An epithelial cell that is part_of a umbilical artery. http://purl.obolibrary.org/obo/GO_0032239 regulation of nucleobase-containing compound transport http://purl.obolibrary.org/obo/GO_0051049 regulation of transport Any process that modulates the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/CL_0010004 mononuclear cell of bone marrow http://purl.obolibrary.org/obo/CL_1001610 bone marrow hematopoietic cell A mononuclear cell that is part_of a bone marrow. http://purl.obolibrary.org/obo/GO_0032240 negative regulation of nucleobase-containing compound transport http://purl.obolibrary.org/obo/GO_0051051 negative regulation of transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/CL_0010005 atrioventricular bundle cell http://purl.obolibrary.org/obo/CL_0010007 His-Purkinje system cell A specialized cardiomyocyte that transmit signals from the AV node to the cardiac Purkinje fibers. http://purl.obolibrary.org/obo/CL_0010006 cardiac blood vessel endothelial cell http://purl.obolibrary.org/obo/CL_0010008 cardiac endothelial cell Any blood vessel endothelial cell that is part of some heart. http://purl.obolibrary.org/obo/GO_0032241 positive regulation of nucleobase-containing compound transport http://purl.obolibrary.org/obo/GO_0051050 positive regulation of transport Any process that activates or increases the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/CL_0010007 His-Purkinje system cell http://purl.obolibrary.org/obo/CL_0002494 cardiocyte Any cell that is part of some His-Purkinje system. http://purl.obolibrary.org/obo/GO_0032252 secretory granule localization http://purl.obolibrary.org/obo/GO_0051648 vesicle localization Any process in which a secretory granule is transported to, and/or maintained in, a specific location within the cell. http://purl.obolibrary.org/obo/CL_0010008 cardiac endothelial cell http://purl.obolibrary.org/obo/CL_0002494 cardiocyte Any endothelial cell that is part of some heart. http://purl.obolibrary.org/obo/CL_0010009 camera-type eye photoreceptor cell http://purl.obolibrary.org/obo/CL_0009004 retinal cell Any photoreceptor cell that is part of some camera-type eye. http://purl.obolibrary.org/obo/GO_0032253 dense core granule localization http://purl.obolibrary.org/obo/GO_0032252 secretory granule localization Any process in which a dense core granule is transported to, and/or maintained in, a specific location within the cell. http://purl.obolibrary.org/obo/CL_0010010 cerebellar stellate cell http://purl.obolibrary.org/obo/CL_0000691 stellate interneuron A GABAergic interneuron that is located in the molecular layer of the cerebellum. This cell receives excitatory inputs primarily from parallel fibers and plays a crucial role in feed-forward inhibition by suppressing the activity of Purkinje cells and modulating the output of the cerebellar cortex. The stellate cell is part of the local circuitry that contributes to the fine-tuning of motor coordination and a regulator of cerebellar blood flow via neurovascular coupling. http://purl.obolibrary.org/obo/GO_0032272 negative regulation of protein polymerization http://purl.obolibrary.org/obo/GO_0032271 regulation of protein polymerization Any process that stops, prevents, or reduces the frequency, rate or extent of the process of creating protein polymers. http://purl.obolibrary.org/obo/GO_0032273 positive regulation of protein polymerization http://purl.obolibrary.org/obo/GO_0032271 regulation of protein polymerization Any process that activates or increases the frequency, rate or extent of the process of creating protein polymers. http://purl.obolibrary.org/obo/CL_0010011 cerebral cortex GABAergic interneuron http://purl.obolibrary.org/obo/CL_0011005 GABAergic interneuron A GABAergic interneuron whose soma is located in the cerebral cortex. http://purl.obolibrary.org/obo/GO_0032274 gonadotropin secretion http://purl.obolibrary.org/obo/GO_0060986 endocrine hormone secretion The regulated release of a gonadotropin, any hormone that stimulates the gonads, especially follicle-stimulating hormone and luteinizing hormone. http://purl.obolibrary.org/obo/CL_0010012 cerebral cortex neuron http://purl.obolibrary.org/obo/CL_0012001 neuron of the forebrain A CNS neuron of the cerebral cortex. http://purl.obolibrary.org/obo/GO_0032275 luteinizing hormone secretion http://purl.obolibrary.org/obo/GO_0032274 gonadotropin secretion The regulated release of luteinizing hormone, a gonadotropic glycoprotein hormone secreted by the anterior pituitary. http://purl.obolibrary.org/obo/CL_0010020 cardiac glial cell http://purl.obolibrary.org/obo/CL_0002494 cardiocyte Any glial cell that is part of some heart. http://purl.obolibrary.org/obo/GO_0032276 regulation of gonadotropin secretion http://purl.obolibrary.org/obo/GO_0046883 regulation of hormone secretion Any process that modulates the frequency, rate or extent of the regulated release of a gonadotropin. http://purl.obolibrary.org/obo/CL_0010021 cardiac myoblast http://purl.obolibrary.org/obo/CL_0000056 myoblast Any myoblast that develops into some cardiac muscle cell. http://purl.obolibrary.org/obo/GO_0032277 negative regulation of gonadotropin secretion http://purl.obolibrary.org/obo/GO_0046888 negative regulation of hormone secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a gonadotropin. http://purl.obolibrary.org/obo/CL_0010022 cardiac neuron http://purl.obolibrary.org/obo/CL_2000032 peripheral nervous system neuron A neuron that has its soma in the heart. http://purl.obolibrary.org/obo/GO_0032278 positive regulation of gonadotropin secretion http://purl.obolibrary.org/obo/GO_0046887 positive regulation of hormone secretion Any process that activates or increases the frequency, rate or extent of the regulated release of a gonadotropin. http://purl.obolibrary.org/obo/CL_0011000 dorsal horn interneuron http://purl.obolibrary.org/obo/CL_0005000 spinal cord interneuron A CNS interneuron located in the dorsal horn of the spinal cord. http://purl.obolibrary.org/obo/GO_0032288 myelin assembly http://purl.obolibrary.org/obo/GO_0010927 cellular component assembly involved in morphogenesis The process in which the wraps of cell membrane that constitute myelin are laid down around an axon in the central or peripheral nervous system. http://purl.obolibrary.org/obo/CL_0011001 spinal cord motor neuron http://purl.obolibrary.org/obo/CL_2000029 central nervous system neuron A motor neuron that passes from the spinal cord toward or to a muscle and conducts an impulse that causes movement. http://purl.obolibrary.org/obo/CL_0011002 lateral motor column neuron http://purl.obolibrary.org/obo/CL_0011001 spinal cord motor neuron A motor neuron that is generated only on limb levels and send axons into the limb mesenchyme. http://purl.obolibrary.org/obo/GO_0032289 central nervous system myelin formation http://purl.obolibrary.org/obo/GO_0032288 myelin assembly The process in which the wraps of cell membrane that constitute myelin are laid down around an axon by an oligodendrocyte in the central nervous system. http://purl.obolibrary.org/obo/CL_0011003 magnocellular neurosecretory cell http://purl.obolibrary.org/obo/CL_0012001 neuron of the forebrain A neurosecretory neuron residing mainly in the hypothalamic supraoptic and paraventricular nuclei and in a number of smaller accessory cell groups between these two nuclei, that is capable of secreting the hormones oxytocin or vasopressin, and sometimes both, into the systemic circulation. http://purl.obolibrary.org/obo/GO_0032290 peripheral nervous system myelin formation http://purl.obolibrary.org/obo/GO_0032288 myelin assembly The process in which the wraps of cell membrane that constitute myelin are laid down around an axon by Schwann cells in the peripheral nervous system. http://purl.obolibrary.org/obo/GO_0032291 axon ensheathment in central nervous system http://purl.obolibrary.org/obo/GO_0008366 axon ensheathment The process in which a glial cell membrane closes around an axon in the central nervous system. This can be a myelinating or a non-myelinating neuron-glial interaction. http://purl.obolibrary.org/obo/CL_0011004 lens fiber cell http://purl.obolibrary.org/obo/CL_0002222 vertebrate lens cell A vetebrate lens cell that is any of the elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye. http://purl.obolibrary.org/obo/GO_0032292 peripheral nervous system axon ensheathment http://purl.obolibrary.org/obo/GO_0008366 axon ensheathment The process in which a Schwann cell membrane closes around an axon in the peripheral nervous system. This can be a myelinating or a non-myelinating neuron-glial interaction. http://purl.obolibrary.org/obo/CL_0011005 GABAergic interneuron http://purl.obolibrary.org/obo/CL_0000617 GABAergic neuron An interneuron that uses GABA as a vesicular neurotransmitter. These interneurons are inhibitory http://purl.obolibrary.org/obo/CL_0011006 Lugaro cell http://purl.obolibrary.org/obo/CL_0008059 GABA-Gly neuron A cerebellar interneuron characterized by a spindle-shaped or triangular soma, parasagittally oriented and located at the border between the granular layer and the Purkinje cell layer. The Lugaro cell extends dendrites predominantly in the parasagittal plane, forming synaptic interactions with basket, stellate, and Golgi cells. Its axonal projections extend upward into the molecular layer, where they form a parasagittal plexus and emit long transverse collaterals that run parallel to the long axis of the cerebellar folia. The Lugaro cell is capable of co-releasing GABA and glycine, as evidenced by the expression of glutamate decarboxylase (GAD65/67) and the glycine transporter GlyT2. http://purl.obolibrary.org/obo/GO_0032330 regulation of chondrocyte differentiation http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the frequency, rate or extent of chondrocyte differentiation. http://purl.obolibrary.org/obo/GO_0032331 negative regulation of chondrocyte differentiation http://purl.obolibrary.org/obo/GO_0061037 negative regulation of cartilage development Any process that stops, prevents, or reduces the frequency, rate or extent of chondrocyte differentiation. http://purl.obolibrary.org/obo/CL_0011100 galanergic neuron http://purl.obolibrary.org/obo/CL_0000540 neuron Neuron that secretes the neurotransmitter galanin. http://purl.obolibrary.org/obo/GO_0032332 positive regulation of chondrocyte differentiation http://purl.obolibrary.org/obo/GO_0045597 positive regulation of cell differentiation Any process that activates or increases the frequency, rate or extent of chondrocyte differentiation. http://purl.obolibrary.org/obo/GO_0032341 aldosterone metabolic process http://purl.obolibrary.org/obo/GO_0042180 ketone metabolic process The chemical reactions and pathways involving aldosterone, a corticosteroid hormone that is produced by the zona glomerulosa of the adrenal cortex and regulates salt (sodium and potassium) and water balance. http://purl.obolibrary.org/obo/CL_0011101 chorionic trophoblast cell http://purl.obolibrary.org/obo/CL_0000351 trophoblast cell Cells of the uterine chorion that acquire specialized structural and/or functional features that characterize chorionic trophoblasts. These cells will migrate towards the spongiotrophoblast layer and give rise to syncytiotrophoblasts of the labyrinthine layer. http://purl.obolibrary.org/obo/GO_0032342 aldosterone biosynthetic process http://purl.obolibrary.org/obo/GO_0032341 aldosterone metabolic process The chemical reactions and pathways resulting in the formation of aldosterone, a corticosteroid hormone that is produced by the zona glomerulosa of the adrenal cortex and regulates salt (sodium and potassium) and water balance. http://purl.obolibrary.org/obo/GO_0032343 aldosterone catabolic process http://purl.obolibrary.org/obo/GO_0046185 aldehyde catabolic process The chemical reactions and pathways resulting in the breakdown of aldosterone, a corticosteroid hormone that is produced by the zona glomerulosa of the adrenal cortex and regulates salt (sodium and potassium) and water balance. http://purl.obolibrary.org/obo/CL_0011102 parasympathetic neuron http://purl.obolibrary.org/obo/CL_0000107 autonomic neuron Parasympathetic neurons are part of the parasympathetic nervous sysem and the cell bodies lie in the brain and sacral region of the spinal cord. The neurons are mainly cholinergic. http://purl.obolibrary.org/obo/GO_0032344 regulation of aldosterone metabolic process http://purl.obolibrary.org/obo/GO_0062012 regulation of small molecule metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving aldosterone. http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron http://purl.obolibrary.org/obo/CL_0000107 autonomic neuron Sympathetic neurons are part of the sympathetic nervous system and are primarily adrenergic producing the neurotransmitter noradrenalin along with other neuropeptides. http://purl.obolibrary.org/obo/CL_0011104 interplexiform cell http://purl.obolibrary.org/obo/CL_0000748 retinal bipolar neuron A type of interneuron in the retinal inner nuclear layer which carries information from the inner plexiform layer and the outer plexiform layer. http://purl.obolibrary.org/obo/GO_0032347 regulation of aldosterone biosynthetic process http://purl.obolibrary.org/obo/GO_1902930 regulation of alcohol biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of aldosterone. http://purl.obolibrary.org/obo/GO_0032348 negative regulation of aldosterone biosynthetic process http://purl.obolibrary.org/obo/GO_1902931 negative regulation of alcohol biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of aldosterone. http://purl.obolibrary.org/obo/CL_0011105 dopamanergic interplexiform cell http://purl.obolibrary.org/obo/CL_0011104 interplexiform cell A type of interneuron in the retinal inner nuclear layer which carries information from the inner plexiform layer and the outer plexiform layer, using dopamine. http://purl.obolibrary.org/obo/GO_0032349 positive regulation of aldosterone biosynthetic process http://purl.obolibrary.org/obo/GO_1902932 positive regulation of alcohol biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of aldosterone. http://purl.obolibrary.org/obo/GO_0032351 negative regulation of hormone metabolic process http://purl.obolibrary.org/obo/GO_0009892 negative regulation of metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving any hormone. http://purl.obolibrary.org/obo/CL_0011106 GABAnergic interplexiform cell http://purl.obolibrary.org/obo/CL_0011104 interplexiform cell A type of interneuron in the retinal inner nuclear layer which carries information from the inner plexiform layer and the outer plexiform layer using GABA. http://purl.obolibrary.org/obo/GO_0032352 positive regulation of hormone metabolic process http://purl.obolibrary.org/obo/GO_0009893 positive regulation of metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving any hormone. http://purl.obolibrary.org/obo/GO_0032353 negative regulation of hormone biosynthetic process http://purl.obolibrary.org/obo/GO_0009890 negative regulation of biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hormones. http://purl.obolibrary.org/obo/CL_0011108 colon epithelial cell http://purl.obolibrary.org/obo/CL_0002253 epithelial cell of large intestine Epithelial cell that is part of the colon epithelium. http://purl.obolibrary.org/obo/GO_0032355 response to estradiol http://purl.obolibrary.org/obo/GO_0033993 response to lipid Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen. http://purl.obolibrary.org/obo/CL_0011109 hypocretin-secreting neuron http://purl.obolibrary.org/obo/CL_0000540 neuron A neuron that releases hypocretin as a neurotransmitter. http://purl.obolibrary.org/obo/CL_0011110 histaminergic neuron http://purl.obolibrary.org/obo/CL_0002274 histamine secreting cell Neuron that secretes histamine. http://purl.obolibrary.org/obo/GO_0032364 intracellular oxygen homeostasis http://purl.obolibrary.org/obo/GO_0055082 intracellular chemical homeostasis A homeostatic process involved in the maintenance of a steady state level of oxygen within a cell. http://purl.obolibrary.org/obo/CL_0011111 hypothalamic gonadotropin-releasing hormone neuron http://purl.obolibrary.org/obo/CL_0012001 neuron of the forebrain a specialized neuroendocrine cell that synthesizes and secretes GnRH decapeptide, a key regulator of reproductive function. It originates from the olfactory placode during embryonic development and migrates into the forebrain where it localises predominantly in the hypothalamus and in humans, in extrahypothalamic regions like the basal ganglia (Skrapits et al., 2021). This cell regulates reproduction by secreting GnRH into the pituitary portal vessels to induce the release of gonadotropins into the general circulation. It expresses receptor subunits required for AMPA, NMDA, and kainate receptor signaling and may use glutamate as a neurotransmitter in recurrent collateral innervation. http://purl.obolibrary.org/obo/GO_0032369 negative regulation of lipid transport http://purl.obolibrary.org/obo/GO_1905953 negative regulation of lipid localization Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0032370 positive regulation of lipid transport http://purl.obolibrary.org/obo/GO_1905954 positive regulation of lipid localization Any process that activates or increases the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/CL_0011113 spiral ganglion neuron http://purl.obolibrary.org/obo/CL_2000032 peripheral nervous system neuron Neuron found in the spiral ganglion. http://purl.obolibrary.org/obo/GO_0032377 regulation of intracellular lipid transport http://purl.obolibrary.org/obo/GO_0032386 regulation of intracellular transport Any process that modulates the frequency, rate or extent of the directed movement of lipids within cells. http://purl.obolibrary.org/obo/GO_0032378 negative regulation of intracellular lipid transport http://purl.obolibrary.org/obo/GO_0032387 negative regulation of intracellular transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids within cells. http://purl.obolibrary.org/obo/CL_0012000 astrocyte of the forebrain http://purl.obolibrary.org/obo/CL_2000005 brain macroglial cell An astrocyte of the forebrain. http://purl.obolibrary.org/obo/GO_0032379 positive regulation of intracellular lipid transport http://purl.obolibrary.org/obo/GO_0032388 positive regulation of intracellular transport Any process that activates or increases the frequency, rate or extent of the directed movement of lipids within cells. http://purl.obolibrary.org/obo/CL_0012001 neuron of the forebrain http://purl.obolibrary.org/obo/CL_2000029 central nervous system neuron A CNS neuron of the forebrain. http://purl.obolibrary.org/obo/CL_0013000 forebrain radial glial cell http://purl.obolibrary.org/obo/CL_0000681 radial glial cell Any radial glial cell that is part of some forebrain. http://purl.obolibrary.org/obo/GO_0032386 regulation of intracellular transport http://purl.obolibrary.org/obo/GO_0060341 regulation of cellular localization Any process that modulates the frequency, rate or extent of the directed movement of substances within cells. http://purl.obolibrary.org/obo/CL_0015000 cranial motor neuron http://purl.obolibrary.org/obo/CL_0000100 motor neuron Motor neuron that innervate muscles that control eye, jaw, and facial movements of the vertebrate head and parasympathetic neurons that innervate certain glands and organs. http://purl.obolibrary.org/obo/GO_0032387 negative regulation of intracellular transport http://purl.obolibrary.org/obo/GO_0051051 negative regulation of transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances within cells. http://purl.obolibrary.org/obo/CL_1000001 retrotrapezoid nucleus neuron http://purl.obolibrary.org/obo/CL_2000029 central nervous system neuron Any neuron that has its soma located in some retrotrapezoid nucleus. http://purl.obolibrary.org/obo/GO_0032388 positive regulation of intracellular transport http://purl.obolibrary.org/obo/GO_0051050 positive regulation of transport Any process that activates or increases the frequency, rate or extent of the directed movement of substances within cells. http://purl.obolibrary.org/obo/CL_1000022 mesonephric nephron tubule epithelial cell http://purl.obolibrary.org/obo/CL_1000507 kidney tubule cell Any epithelial cell that is part of some mesonephric nephron tubule. http://purl.obolibrary.org/obo/GO_0032394 MHC class Ib receptor activity http://purl.obolibrary.org/obo/GO_0140375 immune receptor activity Combining with an MHC class Ib protein complex and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. Class Ib here refers to non-classical class I molecules, such as those of the CD1 or HLA-E gene families. http://purl.obolibrary.org/obo/CL_1000042 forebrain neuroblast http://purl.obolibrary.org/obo/CL_0002319 neural cell Any neuroblast (sensu Vertebrata) that is part of some forebrain. http://purl.obolibrary.org/obo/GO_0032400 melanosome localization http://purl.obolibrary.org/obo/GO_0051875 pigment granule localization Any process in which a melanosome is transported to, and/or maintained in, a specific location within the cell. http://purl.obolibrary.org/obo/CL_1000050 lateral line nerve glial cell http://purl.obolibrary.org/obo/CL_0000125 glial cell Any glial cell that is part of some lateral line nerve. http://purl.obolibrary.org/obo/GO_0032401 establishment of melanosome localization http://purl.obolibrary.org/obo/GO_0051905 establishment of pigment granule localization The directed movement of a melanosome to a specific location. http://purl.obolibrary.org/obo/CL_1000073 spinal cord radial glial cell http://purl.obolibrary.org/obo/CL_0000681 radial glial cell Any radial glial cell that is part of some spinal cord. http://purl.obolibrary.org/obo/CL_1000090 pronephric nephron tubule epithelial cell http://purl.obolibrary.org/obo/CL_1000507 kidney tubule cell Any epithelial cell that is part of some pronephric nephron tubule. http://purl.obolibrary.org/obo/GO_0032402 melanosome transport http://purl.obolibrary.org/obo/GO_0051904 pigment granule transport The directed movement of melanosomes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/CL_1000123 metanephric nephron tubule epithelial cell http://purl.obolibrary.org/obo/CL_1000507 kidney tubule cell Any epithelial cell that is part of some metanephric nephron tubule. http://purl.obolibrary.org/obo/GO_0032410 negative regulation of transporter activity http://purl.obolibrary.org/obo/GO_0051051 negative regulation of transport Any process that stops or reduces the activity of a transporter. http://purl.obolibrary.org/obo/CL_1000143 lung goblet cell http://purl.obolibrary.org/obo/CL_1000272 lung secretory cell Any goblet cell that is part of some lung epithelium. http://purl.obolibrary.org/obo/GO_0032411 positive regulation of transporter activity http://purl.obolibrary.org/obo/GO_0051050 positive regulation of transport Any process that activates or increases the activity of a transporter. http://purl.obolibrary.org/obo/CL_1000147 cardiac valve cell http://purl.obolibrary.org/obo/CL_0002494 cardiocyte A cell that is part of a cardiac valve. http://purl.obolibrary.org/obo/GO_0032414 positive regulation of ion transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0034767 positive regulation of monoatomic ion transmembrane transport Any process that activates or increases the activity of an ion transporter. http://purl.obolibrary.org/obo/CL_1000155 Malpighian tubule stellate cell http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell A specialized epithelial secretory cell that moves chloride ions and water across the tubule epithelium. http://purl.obolibrary.org/obo/GO_0032418 lysosome localization http://purl.obolibrary.org/obo/GO_1990849 vacuolar localization Any process in which a lysosome is transported to, and/or maintained in, a specific location. http://purl.obolibrary.org/obo/CL_1000182 malpighian tubule tip cell http://purl.obolibrary.org/obo/CL_0000423 tip cell Any tip cell that is part of some Malpighian tubule. http://purl.obolibrary.org/obo/GO_0032438 melanosome organization http://purl.obolibrary.org/obo/GO_0048753 pigment granule organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a melanosome. A melanosome is a tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored. http://purl.obolibrary.org/obo/CL_1000191 pillar cell http://purl.obolibrary.org/obo/CL_0002490 organ of Corti supporting cell A rod-like cell in the inner ear, having their heads joined and their bases on the basilar membrane widely separated so as to form a spiral tunnel known as the tunnel of Corti. http://purl.obolibrary.org/obo/GO_0032468 Golgi calcium ion homeostasis http://purl.obolibrary.org/obo/GO_0006874 intracellular calcium ion homeostasis Any process involved in the maintenance of an internal steady state of calcium ions within the Golgi apparatus of a cell or between the Golgi and its surroundings. http://purl.obolibrary.org/obo/CL_1000217 growth plate cartilage chondrocyte http://purl.obolibrary.org/obo/CL_0000138 chondrocyte Any chondrocyte that is part of some growth plate cartilage. http://purl.obolibrary.org/obo/GO_0032472 Golgi calcium ion transport http://purl.obolibrary.org/obo/GO_0006816 calcium ion transport The directed movement of calcium ions (Ca2+) into, out of or within the Golgi apparatus. http://purl.obolibrary.org/obo/CL_1000222 stomach neuroendocrine cell http://purl.obolibrary.org/obo/CL_1001517 stomach enteroendocrine cell A specialised neuroendocrine cell located in the gastric mucosa that regulates digestive processes including acid secretion and gut motility. This cell stores hormones in large dense core vesicles and synaptic-like microvesicles. http://purl.obolibrary.org/obo/GO_0032479 regulation of type I interferon production http://purl.obolibrary.org/obo/GO_0001817 regulation of cytokine production Any process that modulates the frequency, rate, or extent of interferon type I production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families. http://purl.obolibrary.org/obo/CL_1000223 pulmonary neuroendocrine cell http://purl.obolibrary.org/obo/CL_1000272 lung secretory cell A neuroendocrine cell that is part of respiratory epithelium of the lung and is involved in the sensory detection of environmental stimuli, including hypoxia, nicotine and air pressure. Ultrastructurally, this cell type is characterized by the presence of cytoplasmic dense core granules, which are considered the storage sites of amine and peptide hormones. Pulmonary neuroendocrine cells are innervated and appear as solitary cells or as clustered masses, localized at airway bifurcation sites, called neuroepithelial bodies that can release serotonin in response to hypoxia and interact with sensory nerve terminals. Pulmonary neuroendocrine cells also function as reserve stem cells that repair the surrounding epithelium after injury. http://purl.obolibrary.org/obo/GO_0032480 negative regulation of type I interferon production http://purl.obolibrary.org/obo/GO_0032479 regulation of type I interferon production Any process that stops, prevents, or reduces the frequency, rate, or extent of type I interferon production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families. http://purl.obolibrary.org/obo/GO_0032481 positive regulation of type I interferon production http://purl.obolibrary.org/obo/GO_0032479 regulation of type I interferon production Any process that activates or increases the frequency, rate, or extent of type I interferon production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families. http://purl.obolibrary.org/obo/CL_1000236 posterior lateral line nerve glial cell http://purl.obolibrary.org/obo/CL_1000050 lateral line nerve glial cell Any glial cell that is part of some posterior lateral line nerve. http://purl.obolibrary.org/obo/GO_0032528 microvillus organization http://purl.obolibrary.org/obo/GO_0120036 plasma membrane bounded cell projection organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microvillus, a thin cylindrical membrane-covered projection on the surface of a cell. http://purl.obolibrary.org/obo/GO_0032529 follicle cell microvillus organization http://purl.obolibrary.org/obo/GO_0032528 microvillus organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microvillus on a follicle cell. A microvillus is a thin cylindrical membrane-covered projection on the surface of an animal cell containing a core bundle of actin filaments. http://purl.obolibrary.org/obo/CL_1000239 anterior lateral line nerve glial cell http://purl.obolibrary.org/obo/CL_1000050 lateral line nerve glial cell Any glial cell that is part of some anterior lateral line nerve. http://purl.obolibrary.org/obo/CL_1000245 posterior lateral line ganglion neuron http://purl.obolibrary.org/obo/CL_2000031 lateral line ganglion neuron Any peripheral nervous system neuron that has its soma located in some posterior lateral line ganglion. http://purl.obolibrary.org/obo/GO_0032530 regulation of microvillus organization http://purl.obolibrary.org/obo/GO_0120035 regulation of plasma membrane bounded cell projection organization Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a microvillus. http://purl.obolibrary.org/obo/CL_1000271 lung multiciliated epithelial cell http://purl.obolibrary.org/obo/CL_4030034 respiratory tract multiciliated cell An epithelial cell that is part of the lung epithelium. This cell is characterised by the presence of cilia on its apical surface. http://purl.obolibrary.org/obo/GO_0032531 regulation of follicle cell microvillus organization http://purl.obolibrary.org/obo/GO_0032530 regulation of microvillus organization Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a microvillus on a follicle cell. http://purl.obolibrary.org/obo/CL_1000272 lung secretory cell http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell Any secretory cell that is part of some lung. http://purl.obolibrary.org/obo/GO_0032534 regulation of microvillus assembly http://purl.obolibrary.org/obo/GO_0120032 regulation of plasma membrane bounded cell projection assembly A process that modulates the formation of a microvillus. http://purl.obolibrary.org/obo/CL_1000274 trophectodermal cell http://purl.obolibrary.org/obo/CL_0000349 extraembryonic cell An extraembryonic cell that is part of the trophectoderm, representing the first lineage to differentiate in the embryo. This cell is crucial for implantation into the uterine wall and differentiates into trophoblast cells, which contribute to placenta formation and facilitate maternal-fetal nutrient and signal exchange. http://purl.obolibrary.org/obo/CL_1000275 smooth muscle cell of small intestine http://purl.obolibrary.org/obo/CL_0002504 enteric smooth muscle cell A smooth muscle cell that is part of the small intestine. http://purl.obolibrary.org/obo/GO_0032543 mitochondrial translation http://purl.obolibrary.org/obo/GO_0006412 translation The chemical reactions and pathways resulting in the formation of a protein in a mitochondrion. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein; the mitochondrion has its own ribosomes and transfer RNAs, and uses a genetic code that differs from the nuclear code. http://purl.obolibrary.org/obo/CL_1000276 smooth muscle fiber of duodenum http://purl.obolibrary.org/obo/CL_1000275 smooth muscle cell of small intestine A smooth muscle cell that is part of the duodenum. http://purl.obolibrary.org/obo/CL_1000277 smooth muscle fiber of jejunum http://purl.obolibrary.org/obo/CL_1000275 smooth muscle cell of small intestine A smooth muscle cell that is part of the jejunum. http://purl.obolibrary.org/obo/GO_0032544 plastid translation http://purl.obolibrary.org/obo/GO_0009657 plastid organization The chemical reactions and pathways resulting in the formation of a protein in a plastid. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein; the plastid has its own ribosomes and transfer RNAs, and uses a genetic code that differs from the nuclear code. http://purl.obolibrary.org/obo/CL_1000278 smooth muscle fiber of ileum http://purl.obolibrary.org/obo/CL_1000275 smooth muscle cell of small intestine A smooth muscle cell that is part of the ileum. http://purl.obolibrary.org/obo/CL_1000279 smooth muscle cell of large intestine http://purl.obolibrary.org/obo/CL_0002504 enteric smooth muscle cell A smooth muscle cell that is part of the large intestine. http://purl.obolibrary.org/obo/GO_0032555 purine ribonucleotide binding http://purl.obolibrary.org/obo/GO_0032553 ribonucleotide binding Binding to a purine ribonucleotide, any compound consisting of a purine ribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety. http://purl.obolibrary.org/obo/CL_1000280 smooth muscle cell of colon http://purl.obolibrary.org/obo/CL_1000279 smooth muscle cell of large intestine A smooth muscle cell that is part of the colon. http://purl.obolibrary.org/obo/CL_1000281 smooth muscle cell of cecum http://purl.obolibrary.org/obo/CL_1000280 smooth muscle cell of colon A smooth muscle cell that is part of the cecum. http://purl.obolibrary.org/obo/GO_0032570 response to progesterone http://purl.obolibrary.org/obo/GO_1901654 response to ketone Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a progesterone stimulus. http://purl.obolibrary.org/obo/CL_1000282 smooth muscle fiber of ascending colon http://purl.obolibrary.org/obo/CL_1000280 smooth muscle cell of colon A smooth muscle cell that is part of the ascending colon. http://purl.obolibrary.org/obo/GO_0032589 neuron projection membrane http://purl.obolibrary.org/obo/GO_0031256 leading edge membrane The portion of the plasma membrane surrounding a neuron projection. http://purl.obolibrary.org/obo/CL_1000283 smooth muscle fiber of transverse colon http://purl.obolibrary.org/obo/CL_1000280 smooth muscle cell of colon A smooth muscle cell that is part of the transverse colon. http://purl.obolibrary.org/obo/GO_0032590 dendrite membrane http://purl.obolibrary.org/obo/GO_0032589 neuron projection membrane The portion of the plasma membrane surrounding a dendrite. http://purl.obolibrary.org/obo/CL_1000284 smooth muscle fiber of descending colon http://purl.obolibrary.org/obo/CL_1000280 smooth muscle cell of colon A smooth muscle cell that is part of the descending colon. http://purl.obolibrary.org/obo/GO_0032594 protein transport within lipid bilayer http://purl.obolibrary.org/obo/GO_0006886 intracellular protein transport The directed movement of a protein from one location to another within a lipid bilayer. http://purl.obolibrary.org/obo/CL_1000285 smooth muscle cell of sigmoid colon http://purl.obolibrary.org/obo/CL_1000280 smooth muscle cell of colon A smooth muscle cell that is part of the sigmoid colon. http://purl.obolibrary.org/obo/GO_0032606 type I interferon production http://purl.obolibrary.org/obo/GO_0001816 cytokine production The appearance of type I interferon due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families. http://purl.obolibrary.org/obo/CL_1000286 smooth muscle cell of rectum http://purl.obolibrary.org/obo/CL_1000279 smooth muscle cell of large intestine A smooth muscle cell that is part of the rectum. http://purl.obolibrary.org/obo/CL_1000287 myocyte of anterior internodal tract http://purl.obolibrary.org/obo/CL_0002096 internodal tract myocyte A muscle cell that is part of the anterior internodal tract. http://purl.obolibrary.org/obo/GO_0032609 type II interferon production http://purl.obolibrary.org/obo/GO_0001816 cytokine production The appearance of interferon-gamma due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Interferon-gamma is also known as type II interferon. http://purl.obolibrary.org/obo/CL_1000288 myocyte of atrial branch of anterior internodal tract http://purl.obolibrary.org/obo/CL_0002096 internodal tract myocyte A muscle cell that is part of the atrial branch of anterior internodal tract. http://purl.obolibrary.org/obo/GO_0032611 interleukin-1 beta production http://purl.obolibrary.org/obo/GO_0032612 interleukin-1 production The appearance of interleukin-1 beta due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. http://purl.obolibrary.org/obo/CL_1000289 myocyte of atrial septal branch of anterior internodal tract http://purl.obolibrary.org/obo/CL_0002096 internodal tract myocyte A muscle cell that is part of the atrial septal branch of anterior internodal tract. http://purl.obolibrary.org/obo/GO_0032612 interleukin-1 production http://purl.obolibrary.org/obo/GO_0001816 cytokine production The appearance of interleukin-1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. http://purl.obolibrary.org/obo/CL_1000290 myocyte of middle internodal tract http://purl.obolibrary.org/obo/CL_0002096 internodal tract myocyte A muscle cell that is part of the middle internodal tract. http://purl.obolibrary.org/obo/GO_0032613 interleukin-10 production http://purl.obolibrary.org/obo/GO_0001816 cytokine production The appearance of interleukin-10 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. http://purl.obolibrary.org/obo/CL_1000291 myocyte of posterior internodal tract http://purl.obolibrary.org/obo/CL_0002096 internodal tract myocyte A muscle cell that is part of the posterior internodal tract. http://purl.obolibrary.org/obo/CL_1000296 epithelial cell of urethra http://purl.obolibrary.org/obo/CL_1001320 urethra cell An epithelial cell that is part of the urethra. http://purl.obolibrary.org/obo/GO_0032616 interleukin-13 production http://purl.obolibrary.org/obo/GO_0001816 cytokine production The appearance of interleukin-13 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. http://purl.obolibrary.org/obo/CL_1000298 mesothelial cell of dura mater http://purl.obolibrary.org/obo/CL_0002319 neural cell A mesothelial cell that is part of the dura mater. http://purl.obolibrary.org/obo/GO_0032620 interleukin-17 production http://purl.obolibrary.org/obo/GO_0001816 cytokine production The appearance of any member of the interleukin-17 family of cytokines due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. http://purl.obolibrary.org/obo/CL_1000299 fibroblast of connective tissue of prostate http://purl.obolibrary.org/obo/CL_0002622 prostate stromal cell A fibroblast that is part of the connective tissue of prostate. http://purl.obolibrary.org/obo/GO_0032623 interleukin-2 production http://purl.obolibrary.org/obo/GO_0001816 cytokine production The appearance of interleukin-2 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. http://purl.obolibrary.org/obo/CL_1000300 fibroblast of outer membrane of prostatic capsule http://purl.obolibrary.org/obo/CL_0002622 prostate stromal cell A fibroblast that is part of the outer membrane of prostatic capsule. http://purl.obolibrary.org/obo/GO_0032626 interleukin-22 production http://purl.obolibrary.org/obo/GO_0001816 cytokine production The appearance of interleukin-22 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. http://purl.obolibrary.org/obo/CL_1000301 fibroblast of subepithelial connective tissue of prostatic gland http://purl.obolibrary.org/obo/CL_0002622 prostate stromal cell A fibroblast that is part of the subepithelial connective tissue of prostatic gland. http://purl.obolibrary.org/obo/GO_0032633 interleukin-4 production http://purl.obolibrary.org/obo/GO_0001816 cytokine production The appearance of interleukin-4 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. http://purl.obolibrary.org/obo/CL_1000302 fibroblast of papillary layer of dermis http://purl.obolibrary.org/obo/CL_0002551 fibroblast of dermis A fibroblast that is part of the papillary layer of dermis. http://purl.obolibrary.org/obo/GO_0032634 interleukin-5 production http://purl.obolibrary.org/obo/GO_0001816 cytokine production The appearance of interleukin-5 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. http://purl.obolibrary.org/obo/CL_1000303 fibroblast of areolar connective tissue http://purl.obolibrary.org/obo/CL_0000057 fibroblast A fibroblast that is part of the areolar connective tissue. http://purl.obolibrary.org/obo/CL_1000304 fibroblast of connective tissue of nonglandular part of prostate http://purl.obolibrary.org/obo/CL_0002622 prostate stromal cell A fibroblast that is part of the connective tissue of nonglandular part of prostate. http://purl.obolibrary.org/obo/GO_0032635 interleukin-6 production http://purl.obolibrary.org/obo/GO_0001816 cytokine production The appearance of interleukin-6 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. http://purl.obolibrary.org/obo/CL_1000305 fibroblast of connective tissue of glandular part of prostate http://purl.obolibrary.org/obo/CL_0002622 prostate stromal cell A fibroblast that is part of the connective tissue of glandular part of prostate. http://purl.obolibrary.org/obo/GO_0032637 interleukin-8 production http://purl.obolibrary.org/obo/GO_0001816 cytokine production The appearance of interleukin-8 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. http://purl.obolibrary.org/obo/CL_1000306 fibroblast of tunica adventitia of artery http://purl.obolibrary.org/obo/CL_4052030 adventitial fibroblast A fibroblast that is part of the tunica adventitia of artery. http://purl.obolibrary.org/obo/GO_0032638 interleukin-9 production http://purl.obolibrary.org/obo/GO_0001816 cytokine production The appearance of interleukin-9 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. http://purl.obolibrary.org/obo/CL_1000307 fibroblast of dense regular elastic tissue http://purl.obolibrary.org/obo/CL_0000057 fibroblast A fibroblast that is part of the dense regular elastic tissue. http://purl.obolibrary.org/obo/GO_0032640 tumor necrosis factor production http://purl.obolibrary.org/obo/GO_0071706 tumor necrosis factor superfamily cytokine production The appearance of tumor necrosis factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Tumor necrosis factor is an inflammatory cytokine produced by macrophages/monocytes during acute inflammation and which is responsible for a diverse range of signaling events within cells, leading to necrosis or apoptosis. http://purl.obolibrary.org/obo/CL_1000308 fibrocyte of adventitia of ureter http://purl.obolibrary.org/obo/CL_1000708 ureter adventitial cell A stromal cell that is part of the outer adventitial layer of the ureter. This cell type is marked by expression of periostin (POSTN) in mice, and it is derived from Foxd1+ mesenchymal progenitors around embryonic day 12.5. The adventitial fibrocyte initiates differentiation earlier than smooth muscle cells and becomes terminally differentiated by E16.5-18.5 in mice, exhibiting low proliferative capacity in adulthood. http://purl.obolibrary.org/obo/GO_0032649 regulation of type II interferon production http://purl.obolibrary.org/obo/GO_0001817 regulation of cytokine production Any process that modulates the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon. http://purl.obolibrary.org/obo/CL_1000309 epicardial adipocyte http://purl.obolibrary.org/obo/CL_0002494 cardiocyte An adipocyte that is part of the epicardial fat. http://purl.obolibrary.org/obo/GO_0032651 regulation of interleukin-1 beta production http://purl.obolibrary.org/obo/GO_0032652 regulation of interleukin-1 production Any process that modulates the frequency, rate, or extent of interleukin-1 beta production. http://purl.obolibrary.org/obo/CL_1000310 adipocyte of epicardial fat of right ventricle http://purl.obolibrary.org/obo/CL_1000309 epicardial adipocyte An adipocyte that is part of the epicardial fat of right ventricle. http://purl.obolibrary.org/obo/GO_0032652 regulation of interleukin-1 production http://purl.obolibrary.org/obo/GO_0001817 regulation of cytokine production Any process that modulates the frequency, rate, or extent of interleukin-1 production. http://purl.obolibrary.org/obo/CL_1000311 adipocyte of epicardial fat of left ventricle http://purl.obolibrary.org/obo/CL_1000309 epicardial adipocyte An adipocyte that is part of the epicardial fat of left ventricle. http://purl.obolibrary.org/obo/GO_0032653 regulation of interleukin-10 production http://purl.obolibrary.org/obo/GO_0001817 regulation of cytokine production Any process that modulates the frequency, rate, or extent of interleukin-10 production. http://purl.obolibrary.org/obo/CL_1000312 bronchial goblet cell http://purl.obolibrary.org/obo/CL_0019003 tracheobronchial goblet cell A goblet cell that is part of the epithelium of bronchus. http://purl.obolibrary.org/obo/GO_0032656 regulation of interleukin-13 production http://purl.obolibrary.org/obo/GO_0001817 regulation of cytokine production Any process that modulates the frequency, rate, or extent of interleukin-13 production. http://purl.obolibrary.org/obo/CL_1000313 gastric goblet cell http://purl.obolibrary.org/obo/CL_0002180 mucous cell of stomach A goblet cell that is part of the epithelium of stomach. http://purl.obolibrary.org/obo/GO_0032660 regulation of interleukin-17 production http://purl.obolibrary.org/obo/GO_0001817 regulation of cytokine production Any process that modulates the frequency, rate, or extent of production of any member of the interleukin-17 family of cytokines. http://purl.obolibrary.org/obo/CL_1000314 gastric cardiac gland goblet cell http://purl.obolibrary.org/obo/CL_1000313 gastric goblet cell A goblet cell that is part of the epithelium of gastric cardiac gland. http://purl.obolibrary.org/obo/GO_0032663 regulation of interleukin-2 production http://purl.obolibrary.org/obo/GO_0001817 regulation of cytokine production Any process that modulates the frequency, rate, or extent of interleukin-2 production. http://purl.obolibrary.org/obo/CL_1000315 principal gastric gland goblet cell http://purl.obolibrary.org/obo/CL_1000313 gastric goblet cell A goblet cell that is part of the epithelium of principal gastric gland. http://purl.obolibrary.org/obo/GO_0032666 regulation of interleukin-22 production http://purl.obolibrary.org/obo/GO_0001817 regulation of cytokine production Any process that modulates the frequency, rate, or extent of interleukin-22 production. http://purl.obolibrary.org/obo/CL_1000317 intestinal villus goblet cell http://purl.obolibrary.org/obo/CL_1000495 small intestine goblet cell A goblet cell that is part of the epithelium of intestinal villus. http://purl.obolibrary.org/obo/GO_0032673 regulation of interleukin-4 production http://purl.obolibrary.org/obo/GO_0001817 regulation of cytokine production Any process that modulates the frequency, rate, or extent of interleukin-4 production. http://purl.obolibrary.org/obo/CL_1000320 large intestine goblet cell http://purl.obolibrary.org/obo/CL_0002253 epithelial cell of large intestine A goblet cell that is part of the epithelium of large intestine. http://purl.obolibrary.org/obo/CL_1000321 large intestine crypt goblet cell http://purl.obolibrary.org/obo/CL_1000320 large intestine goblet cell A goblet cell that is part of the epithelium of crypt of Lieberkuhn of large intestine. http://purl.obolibrary.org/obo/GO_0032674 regulation of interleukin-5 production http://purl.obolibrary.org/obo/GO_0001817 regulation of cytokine production Any process that modulates the frequency, rate, or extent of interleukin-5 production. http://purl.obolibrary.org/obo/CL_1000322 pancreatic goblet cell http://purl.obolibrary.org/obo/CL_1001599 pancreas exocrine glandular cell A goblet cell that is part of the epithelium of pancreatic duct. http://purl.obolibrary.org/obo/GO_0032675 regulation of interleukin-6 production http://purl.obolibrary.org/obo/GO_0001817 regulation of cytokine production Any process that modulates the frequency, rate, or extent of interleukin-6 production. http://purl.obolibrary.org/obo/CL_1000323 pyloric gastric gland goblet cell http://purl.obolibrary.org/obo/CL_1000313 gastric goblet cell A goblet cell that is part of the epithelium of pyloric gland. http://purl.obolibrary.org/obo/GO_0032677 regulation of interleukin-8 production http://purl.obolibrary.org/obo/GO_0001817 regulation of cytokine production Any process that modulates the frequency, rate, or extent of interleukin-8 production. http://purl.obolibrary.org/obo/CL_1000324 duodenal goblet cell http://purl.obolibrary.org/obo/CL_1001589 duodenum secretory cell A goblet cell that is part of the epithelium proper of duodenum. http://purl.obolibrary.org/obo/GO_0032678 regulation of interleukin-9 production http://purl.obolibrary.org/obo/GO_0001817 regulation of cytokine production Any process that modulates the frequency, rate, or extent of interleukin-9 production. http://purl.obolibrary.org/obo/CL_1000325 jejunal goblet cell http://purl.obolibrary.org/obo/CL_1000317 intestinal villus goblet cell A goblet cell that is part of the epithelium proper of jejunum. http://purl.obolibrary.org/obo/GO_0032680 regulation of tumor necrosis factor production http://purl.obolibrary.org/obo/GO_1903555 regulation of tumor necrosis factor superfamily cytokine production Any process that modulates the frequency, rate or extent of tumor necrosis factor production. http://purl.obolibrary.org/obo/CL_1000326 ileal goblet cell http://purl.obolibrary.org/obo/CL_1000317 intestinal villus goblet cell A goblet cell that is part of the epithelium proper of ileum. http://purl.obolibrary.org/obo/GO_0032689 negative regulation of type II interferon production http://purl.obolibrary.org/obo/GO_0032649 regulation of type II interferon production Any process that stops, prevents, or reduces the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon. http://purl.obolibrary.org/obo/CL_1000327 appendix goblet cell http://purl.obolibrary.org/obo/CL_1000405 epithelial cell of appendix A goblet cell that is part of the epithelium proper of appendix. http://purl.obolibrary.org/obo/GO_0032691 negative regulation of interleukin-1 beta production http://purl.obolibrary.org/obo/GO_0032692 negative regulation of interleukin-1 production Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-1 beta production. http://purl.obolibrary.org/obo/CL_1000329 tracheal goblet cell http://purl.obolibrary.org/obo/CL_0019003 tracheobronchial goblet cell A goblet cell that is part of the epithelium of trachea. http://purl.obolibrary.org/obo/GO_0032692 negative regulation of interleukin-1 production http://purl.obolibrary.org/obo/GO_0032652 regulation of interleukin-1 production Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-1 production. http://purl.obolibrary.org/obo/CL_1000330 serous cell of epithelium of trachea http://purl.obolibrary.org/obo/CL_0019001 tracheobronchial serous cell A serous secreting cell that is part of the epithelium of trachea. http://purl.obolibrary.org/obo/CL_1000331 serous cell of epithelium of bronchus http://purl.obolibrary.org/obo/CL_0019001 tracheobronchial serous cell A serous secreting cell that is part of the epithelium of bronchus. http://purl.obolibrary.org/obo/GO_0032693 negative regulation of interleukin-10 production http://purl.obolibrary.org/obo/GO_0032653 regulation of interleukin-10 production Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-10 production. http://purl.obolibrary.org/obo/CL_1000332 serous cell of epithelium of terminal bronchiole http://purl.obolibrary.org/obo/CL_0019001 tracheobronchial serous cell A serous secreting cell that is part of the epithelium of terminal bronchiole. http://purl.obolibrary.org/obo/GO_0032696 negative regulation of interleukin-13 production http://purl.obolibrary.org/obo/GO_0032656 regulation of interleukin-13 production Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-13 production. http://purl.obolibrary.org/obo/GO_0032700 negative regulation of interleukin-17 production http://purl.obolibrary.org/obo/GO_0032660 regulation of interleukin-17 production Any process that stops, prevents, or reduces the frequency, rate, or extent of production of any member of the interleukin-17 family of cytokines. http://purl.obolibrary.org/obo/CL_1000333 serous cell of epithelium of lobular bronchiole http://purl.obolibrary.org/obo/CL_0019001 tracheobronchial serous cell A serous secreting cell that is part of the epithelium of bronchiole. http://purl.obolibrary.org/obo/CL_1000334 enterocyte of epithelium of small intestine http://purl.obolibrary.org/obo/CL_0002254 epithelial cell of small intestine An enterocyte that is part of the epithelium of small intestine. http://purl.obolibrary.org/obo/GO_0032703 negative regulation of interleukin-2 production http://purl.obolibrary.org/obo/GO_0032663 regulation of interleukin-2 production Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-2 production. http://purl.obolibrary.org/obo/CL_1000335 enterocyte of epithelium of intestinal villus http://purl.obolibrary.org/obo/CL_1000334 enterocyte of epithelium of small intestine An enterocyte that is part of the epithelium of intestinal villus. http://purl.obolibrary.org/obo/GO_0032706 negative regulation of interleukin-22 production http://purl.obolibrary.org/obo/GO_0032666 regulation of interleukin-22 production Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-22 production. http://purl.obolibrary.org/obo/CL_1000337 enterocyte of epithelium of duodenal gland http://purl.obolibrary.org/obo/CL_1000334 enterocyte of epithelium of small intestine An enterocyte that is part of the epithelium of duodenal gland. http://purl.obolibrary.org/obo/GO_0032713 negative regulation of interleukin-4 production http://purl.obolibrary.org/obo/GO_0032673 regulation of interleukin-4 production Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-4 production. http://purl.obolibrary.org/obo/CL_1000338 enterocyte of epithelium of crypt of Lieberkuhn of small intestine http://purl.obolibrary.org/obo/CL_1000334 enterocyte of epithelium of small intestine An enterocyte that is part of the epithelium of crypt of Lieberkuhn of small intestine. http://purl.obolibrary.org/obo/GO_0032714 negative regulation of interleukin-5 production http://purl.obolibrary.org/obo/GO_0032674 regulation of interleukin-5 production Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-5 production. http://purl.obolibrary.org/obo/CL_1000339 enterocyte of epithelium proper of small intestine http://purl.obolibrary.org/obo/CL_1000334 enterocyte of epithelium of small intestine An enterocyte that is part of the epithelium proper of small intestine. http://purl.obolibrary.org/obo/GO_0032715 negative regulation of interleukin-6 production http://purl.obolibrary.org/obo/GO_0032675 regulation of interleukin-6 production Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-6 production. http://purl.obolibrary.org/obo/CL_1000340 enterocyte of epithelium proper of duodenum http://purl.obolibrary.org/obo/CL_1000339 enterocyte of epithelium proper of small intestine An enterocyte that is part of the epithelium proper of duodenum. http://purl.obolibrary.org/obo/GO_0032717 negative regulation of interleukin-8 production http://purl.obolibrary.org/obo/GO_0032677 regulation of interleukin-8 production Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-8 production. http://purl.obolibrary.org/obo/CL_1000341 enterocyte of epithelium proper of jejunum http://purl.obolibrary.org/obo/CL_1000339 enterocyte of epithelium proper of small intestine An enterocyte that is part of the epithelium proper of jejunum. http://purl.obolibrary.org/obo/GO_0032718 negative regulation of interleukin-9 production http://purl.obolibrary.org/obo/GO_0032678 regulation of interleukin-9 production Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-9 production. http://purl.obolibrary.org/obo/CL_1000342 enterocyte of epithelium proper of ileum http://purl.obolibrary.org/obo/CL_1000339 enterocyte of epithelium proper of small intestine An enterocyte that is part of the epithelium proper of ileum. http://purl.obolibrary.org/obo/GO_0032720 negative regulation of tumor necrosis factor production http://purl.obolibrary.org/obo/GO_1903556 negative regulation of tumor necrosis factor superfamily cytokine production Any process that stops, prevents, or reduces the frequency, rate, or extent of tumor necrosis factor production. http://purl.obolibrary.org/obo/CL_1000343 paneth cell of epithelium of small intestine http://purl.obolibrary.org/obo/CL_1001598 small intestine secretory cell A paneth cell that is part of the epithelium of small intestine. http://purl.obolibrary.org/obo/GO_0032729 positive regulation of type II interferon production http://purl.obolibrary.org/obo/GO_0032649 regulation of type II interferon production Any process that activates or increases the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon. http://purl.obolibrary.org/obo/CL_1000344 paneth cell of epithelium proper of small intestine http://purl.obolibrary.org/obo/CL_1000343 paneth cell of epithelium of small intestine A Paneth cell that is part of the epithelium proper of small intestine. http://purl.obolibrary.org/obo/GO_0032731 positive regulation of interleukin-1 beta production http://purl.obolibrary.org/obo/GO_0032732 positive regulation of interleukin-1 production Any process that activates or increases the frequency, rate, or extent of interleukin-1 beta production. http://purl.obolibrary.org/obo/CL_1000345 paneth cell of epithelium of crypt of Lieberkuhn of small intestine http://purl.obolibrary.org/obo/CL_1000343 paneth cell of epithelium of small intestine A paneth cell that is part of the epithelium of crypt of Lieberkuhn of small intestine. http://purl.obolibrary.org/obo/CL_1000346 enterocyte of epithelium proper of large intestine http://purl.obolibrary.org/obo/CL_0002071 enterocyte of epithelium of large intestine An enterocyte that is part of the epithelium proper of large intestine. http://purl.obolibrary.org/obo/GO_0032732 positive regulation of interleukin-1 production http://purl.obolibrary.org/obo/GO_0032652 regulation of interleukin-1 production Any process that activates or increases the frequency, rate, or extent of interleukin-1 production. http://purl.obolibrary.org/obo/CL_1000347 colonocyte http://purl.obolibrary.org/obo/CL_0011108 colon epithelial cell An enterocyte (absorptive epithelial cell) of the colonic epithelium, characterized by a columnar shape. This cell is responsible for the absorption, transport, and metabolization of short-chain fatty acids (SCFAs) produced by gut bacteria, as well as the transport and absorption of water and electrolytes. http://purl.obolibrary.org/obo/GO_0032733 positive regulation of interleukin-10 production http://purl.obolibrary.org/obo/GO_0032653 regulation of interleukin-10 production Any process that activates or increases the frequency, rate, or extent of interleukin-10 production. http://purl.obolibrary.org/obo/GO_0032736 positive regulation of interleukin-13 production http://purl.obolibrary.org/obo/GO_0032656 regulation of interleukin-13 production Any process that activates or increases the frequency, rate, or extent of interleukin-13 production. http://purl.obolibrary.org/obo/CL_1000348 basal cell of epithelium of trachea http://purl.obolibrary.org/obo/CL_0002633 respiratory basal cell A basal cell that is part of the epithelium of trachea. http://purl.obolibrary.org/obo/CL_1000349 basal cell of epithelium of bronchus http://purl.obolibrary.org/obo/CL_0002633 respiratory basal cell A basal cell found in the bronchus epithelium. http://purl.obolibrary.org/obo/GO_0032740 positive regulation of interleukin-17 production http://purl.obolibrary.org/obo/GO_0032660 regulation of interleukin-17 production Any process that activates or increases the frequency, rate, or extent of production of any member of the interleukin-17 family of cytokines. http://purl.obolibrary.org/obo/CL_1000350 basal cell of epithelium of terminal bronchiole http://purl.obolibrary.org/obo/CL_0002633 respiratory basal cell A basal cell that is part of the epithelium of terminal bronchiole. http://purl.obolibrary.org/obo/GO_0032743 positive regulation of interleukin-2 production http://purl.obolibrary.org/obo/GO_0032663 regulation of interleukin-2 production Any process that activates or increases the frequency, rate, or extent of interleukin-2 production. http://purl.obolibrary.org/obo/CL_1000351 basal cell of epithelium of respiratory bronchiole http://purl.obolibrary.org/obo/CL_0002633 respiratory basal cell A basal cell that is part of the epithelium of respiratory bronchiole. http://purl.obolibrary.org/obo/GO_0032746 positive regulation of interleukin-22 production http://purl.obolibrary.org/obo/GO_0032666 regulation of interleukin-22 production Any process that activates or increases the frequency, rate, or extent of interleukin-22 production. http://purl.obolibrary.org/obo/CL_1000352 basal cell of epithelium of lobular bronchiole http://purl.obolibrary.org/obo/CL_0002633 respiratory basal cell A basal cell that is part of the epithelium of bronchiole. http://purl.obolibrary.org/obo/GO_0032753 positive regulation of interleukin-4 production http://purl.obolibrary.org/obo/GO_0032673 regulation of interleukin-4 production Any process that activates or increases the frequency, rate, or extent of interleukin-4 production. http://purl.obolibrary.org/obo/CL_1000353 microfold cell of epithelium of small intestine http://purl.obolibrary.org/obo/CL_0002254 epithelial cell of small intestine A M cell that is part of the epithelium of small intestine. http://purl.obolibrary.org/obo/GO_0032754 positive regulation of interleukin-5 production http://purl.obolibrary.org/obo/GO_0032674 regulation of interleukin-5 production Any process that activates or increases the frequency, rate, or extent of interleukin-5 production. http://purl.obolibrary.org/obo/CL_1000354 microfold cell of epithelium of intestinal villus http://purl.obolibrary.org/obo/CL_1000353 microfold cell of epithelium of small intestine A M cell that is part of the epithelium of intestinal villus. http://purl.obolibrary.org/obo/GO_0032755 positive regulation of interleukin-6 production http://purl.obolibrary.org/obo/GO_0032675 regulation of interleukin-6 production Any process that activates or increases the frequency, rate, or extent of interleukin-6 production. http://purl.obolibrary.org/obo/CL_1000355 microfold cell of epithelium proper of small intestine http://purl.obolibrary.org/obo/CL_1000353 microfold cell of epithelium of small intestine A M cell that is part of the epithelium proper of small intestine. http://purl.obolibrary.org/obo/GO_0032757 positive regulation of interleukin-8 production http://purl.obolibrary.org/obo/GO_0032677 regulation of interleukin-8 production Any process that activates or increases the frequency, rate, or extent of interleukin-8 production. http://purl.obolibrary.org/obo/CL_1000356 microfold cell of epithelium proper of duodenum http://purl.obolibrary.org/obo/CL_1000354 microfold cell of epithelium of intestinal villus A M cell that is part of the epithelium proper of duodenum. http://purl.obolibrary.org/obo/GO_0032758 positive regulation of interleukin-9 production http://purl.obolibrary.org/obo/GO_0032678 regulation of interleukin-9 production Any process that activates or increases the frequency, rate, or extent of interleukin-9 production. http://purl.obolibrary.org/obo/CL_1000357 microfold cell of epithelium proper of jejunum http://purl.obolibrary.org/obo/CL_1000353 microfold cell of epithelium of small intestine A M cell that is part of the epithelium proper of jejunum. http://purl.obolibrary.org/obo/GO_0032760 positive regulation of tumor necrosis factor production http://purl.obolibrary.org/obo/GO_1903557 positive regulation of tumor necrosis factor superfamily cytokine production Any process that activates or increases the frequency, rate or extent of tumor necrosis factor production. http://purl.obolibrary.org/obo/CL_1000358 microfold cell of epithelium proper of ileum http://purl.obolibrary.org/obo/CL_1000353 microfold cell of epithelium of small intestine A M cell that is part of the epithelium proper of ileum. http://purl.obolibrary.org/obo/GO_0032762 mast cell cytokine production http://purl.obolibrary.org/obo/GO_0061082 myeloid leukocyte cytokine production Any process that contributes to cytokine production by a mast cell. http://purl.obolibrary.org/obo/CL_1000359 microfold cell of epithelium proper of appendix http://purl.obolibrary.org/obo/CL_1000405 epithelial cell of appendix A M cell that is part of the epithelium proper of appendix. http://purl.obolibrary.org/obo/GO_0032763 regulation of mast cell cytokine production http://purl.obolibrary.org/obo/GO_0002718 regulation of cytokine production involved in immune response Any process that modulates the frequency, rate, or extent of mast cell cytokine production. http://purl.obolibrary.org/obo/GO_0032764 negative regulation of mast cell cytokine production http://purl.obolibrary.org/obo/GO_0032763 regulation of mast cell cytokine production Any process that stops, prevents, or reduces the frequency, rate, or extent of mast cell cytokine production. http://purl.obolibrary.org/obo/CL_1000360 microfold cell of epithelium proper of large intestine http://purl.obolibrary.org/obo/CL_0002253 epithelial cell of large intestine A M cell that is part of the epithelium proper of large intestine. http://purl.obolibrary.org/obo/GO_0032765 positive regulation of mast cell cytokine production http://purl.obolibrary.org/obo/GO_0032763 regulation of mast cell cytokine production Any process that activates or increases the frequency, rate, or extent of mast cell cytokine production. http://purl.obolibrary.org/obo/GO_0032780 negative regulation of ATP-dependent activity http://purl.obolibrary.org/obo/GO_0043462 regulation of ATP-dependent activity Any process that stops or reduces the rate of an ATP-dependent activity. http://purl.obolibrary.org/obo/GO_0032790 ribosome disassembly http://purl.obolibrary.org/obo/GO_1903008 organelle disassembly The disaggregation of a ribosome into its constituent components; includes the dissociation of ribosomal subunits. http://purl.obolibrary.org/obo/GO_0032808 lacrimal gland development http://purl.obolibrary.org/obo/GO_0048732 gland development The process whose specific outcome is the progression of the lacrimal gland over time, from its formation to the mature structure. The lacrimal gland produces secretions that lubricate and protect the cornea of the eye. http://purl.obolibrary.org/obo/CL_1000361 transitional myocyte of interatrial septum http://purl.obolibrary.org/obo/CL_2000022 cardiac septum cell A transitional myocyte that is part of the interatrial septum. http://purl.obolibrary.org/obo/GO_0032811 negative regulation of epinephrine secretion http://purl.obolibrary.org/obo/GO_0033604 negative regulation of catecholamine secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of epinephrine. http://purl.obolibrary.org/obo/CL_1000362 transitional myocyte of interventricular septum http://purl.obolibrary.org/obo/CL_2000022 cardiac septum cell A transitional myocyte that is part of the interventricular septum. http://purl.obolibrary.org/obo/GO_0032812 positive regulation of epinephrine secretion http://purl.obolibrary.org/obo/GO_0033605 positive regulation of catecholamine secretion Any process that activates or increases the frequency, rate or extent of the regulated release of epinephrine. http://purl.obolibrary.org/obo/GO_0032814 regulation of natural killer cell activation http://purl.obolibrary.org/obo/GO_0051249 regulation of lymphocyte activation Any process that modulates the frequency, rate or extent of natural killer cell activation. http://purl.obolibrary.org/obo/CL_1000363 transitional myocyte of atrial branch of anterior internodal tract http://purl.obolibrary.org/obo/CL_1000480 transitional myocyte of internodal tract A transitional myocyte that is part of the atrial branch of anterior internodal tract. http://purl.obolibrary.org/obo/GO_0032815 negative regulation of natural killer cell activation http://purl.obolibrary.org/obo/GO_0051250 negative regulation of lymphocyte activation Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell activation. http://purl.obolibrary.org/obo/CL_1000364 transitional myocyte of anterior internodal tract http://purl.obolibrary.org/obo/CL_1000480 transitional myocyte of internodal tract A transitional myocyte that is part of the anterior internodal tract. http://purl.obolibrary.org/obo/CL_1000365 transitional myocyte of atrial septal branch of anterior internodal tract http://purl.obolibrary.org/obo/CL_1000480 transitional myocyte of internodal tract A transitional myocyte that is part of the atrial septal branch of anterior internodal tract. http://purl.obolibrary.org/obo/CL_1000366 transitional myocyte of middle internodal tract http://purl.obolibrary.org/obo/CL_1000480 transitional myocyte of internodal tract A transitional myocyte that is part of the middle internodal tract. http://purl.obolibrary.org/obo/GO_0032816 positive regulation of natural killer cell activation http://purl.obolibrary.org/obo/GO_0051251 positive regulation of lymphocyte activation Any process that activates or increases the frequency, rate or extent of natural killer cell activation. http://purl.obolibrary.org/obo/CL_1000367 transitional myocyte of posterior internodal tract http://purl.obolibrary.org/obo/CL_1000480 transitional myocyte of internodal tract A transitional myocyte that is part of the posterior internodal tract. http://purl.obolibrary.org/obo/GO_0032817 regulation of natural killer cell proliferation http://purl.obolibrary.org/obo/GO_0050670 regulation of lymphocyte proliferation Any process that modulates the frequency, rate or extent of natural killer cell proliferation. http://purl.obolibrary.org/obo/CL_1000368 transitional myocyte of anterior division of left branch of atrioventricular bundle http://purl.obolibrary.org/obo/CL_1000370 transitional myocyte of left branch of atrioventricular bundle A transitional myocyte that is part of the anterior division of left branch of atrioventricular bundle. http://purl.obolibrary.org/obo/CL_1000369 transitional myocyte of septal division of left branch of atrioventricular bundle http://purl.obolibrary.org/obo/CL_1000370 transitional myocyte of left branch of atrioventricular bundle A transitional myocyte that is part of the septal division of left branch of atrioventricular bundle. http://purl.obolibrary.org/obo/GO_0032818 negative regulation of natural killer cell proliferation http://purl.obolibrary.org/obo/GO_0050672 negative regulation of lymphocyte proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell proliferation. http://purl.obolibrary.org/obo/CL_1000370 transitional myocyte of left branch of atrioventricular bundle http://purl.obolibrary.org/obo/CL_1000481 transitional myocyte of atrioventricular bundle A transitional myocyte that is part of the left branch of atrioventricular bundle. http://purl.obolibrary.org/obo/CL_1000371 transitional myocyte of right branch of atrioventricular bundle http://purl.obolibrary.org/obo/CL_1000481 transitional myocyte of atrioventricular bundle A transitional myocyte that is part of the right branch of atrioventricular bundle. http://purl.obolibrary.org/obo/GO_0032819 positive regulation of natural killer cell proliferation http://purl.obolibrary.org/obo/GO_0050671 positive regulation of lymphocyte proliferation Any process that activates or increases the frequency, rate or extent of natural killer cell proliferation. http://purl.obolibrary.org/obo/CL_1000372 transitional myocyte of atrial part of atrioventricular bundle http://purl.obolibrary.org/obo/CL_1000481 transitional myocyte of atrioventricular bundle A transitional myocyte that is part of the atrial part of atrioventricular bundle. http://purl.obolibrary.org/obo/CL_1000373 transitional myocyte of ventricular part of atrioventricular bundle http://purl.obolibrary.org/obo/CL_1000481 transitional myocyte of atrioventricular bundle A transitional myocyte that is part of the ventricular part of atrioventricular bundle. http://purl.obolibrary.org/obo/GO_0032823 regulation of natural killer cell differentiation http://purl.obolibrary.org/obo/GO_0045619 regulation of lymphocyte differentiation Any process that modulates the frequency, rate or extent of natural killer cell differentiation. http://purl.obolibrary.org/obo/CL_1000374 transitional myocyte of posterior division of left branch of atrioventricular bundle http://purl.obolibrary.org/obo/CL_1000370 transitional myocyte of left branch of atrioventricular bundle A transitional myocyte that is part of the posterior division of left branch of atrioventricular bundle. http://purl.obolibrary.org/obo/GO_0032824 negative regulation of natural killer cell differentiation http://purl.obolibrary.org/obo/GO_0045620 negative regulation of lymphocyte differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell differentiation. http://purl.obolibrary.org/obo/CL_1000375 myocardial endocrine cell of septal division of left branch of atrioventricular bundle http://purl.obolibrary.org/obo/CL_2000046 ventricular cardiac muscle cell A myocardial endocrine cell that is part of the septal division of left branch of atrioventricular bundle. http://purl.obolibrary.org/obo/CL_1000376 Purkinje myocyte of interventricular septum http://purl.obolibrary.org/obo/CL_2000022 cardiac septum cell A Purkinje myocyte that is part of the interventricular septum. http://purl.obolibrary.org/obo/GO_0032825 positive regulation of natural killer cell differentiation http://purl.obolibrary.org/obo/GO_0045621 positive regulation of lymphocyte differentiation Any process that activates or increases the frequency, rate or extent of natural killer cell differentiation. http://purl.obolibrary.org/obo/CL_1000377 dense-core granulated cell of epithelium of trachea http://purl.obolibrary.org/obo/CL_0008055 respiratory tract secretory epithelial cell A Feyrter cell that is part of the epithelium of trachea. http://purl.obolibrary.org/obo/CL_1000378 type 1 vestibular sensory cell of stato-acoustic epithelium http://purl.obolibrary.org/obo/CL_3000004 peripheral sensory neuron A type I vestibular sensory cell that is part of the stato-acoustic epithelium. http://purl.obolibrary.org/obo/GO_0032829 regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation http://purl.obolibrary.org/obo/GO_0045589 regulation of regulatory T cell differentiation Any process that modulates the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells. http://purl.obolibrary.org/obo/CL_1000379 type 1 vestibular sensory cell of epithelium of macula of utricle of membranous labyrinth http://purl.obolibrary.org/obo/CL_3000004 peripheral sensory neuron A type I vestibular sensory cell that is part of the epithelium of macula of utricle of membranous labyrinth. http://purl.obolibrary.org/obo/CL_1000380 type 1 vestibular sensory cell of epithelium of macula of saccule of membranous labyrinth http://purl.obolibrary.org/obo/CL_3000004 peripheral sensory neuron A type I vestibular sensory cell that is part of the epithelium of macula of saccule of membranous labyrinth. http://purl.obolibrary.org/obo/GO_0032830 negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation http://purl.obolibrary.org/obo/GO_0045590 negative regulation of regulatory T cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells. http://purl.obolibrary.org/obo/CL_1000381 type 1 vestibular sensory cell of epithelium of crista of ampulla of semicircular duct of membranous labyrinth http://purl.obolibrary.org/obo/CL_3000004 peripheral sensory neuron A type I vestibular sensory cell that is part of the epithelium of crista of ampulla of semicircular duct of membranous labyrinth. http://purl.obolibrary.org/obo/CL_1000382 type 2 vestibular sensory cell of stato-acoustic epithelium http://purl.obolibrary.org/obo/CL_3000004 peripheral sensory neuron A type II vestibular sensory cell that is part of the stato-acoustic epithelium. http://purl.obolibrary.org/obo/GO_0032831 positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation http://purl.obolibrary.org/obo/GO_0045591 positive regulation of regulatory T cell differentiation Any process that activates or increases the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells. http://purl.obolibrary.org/obo/CL_1000383 type 2 vestibular sensory cell of epithelium of macula of utricle of membranous labyrinth http://purl.obolibrary.org/obo/CL_3000004 peripheral sensory neuron A type II vestibular sensory cell that is part of the epithelium of macula of utricle of membranous labyrinth. http://purl.obolibrary.org/obo/CL_1000384 type 2 vestibular sensory cell of epithelium of macula of saccule of membranous labyrinth http://purl.obolibrary.org/obo/CL_3000004 peripheral sensory neuron A type II vestibular sensory cell that is part of the epithelium of macula of saccule of membranous labyrinth. http://purl.obolibrary.org/obo/GO_0032835 glomerulus development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the vertebrate kidney. The glomerulus is part of the nephron and is restricted to one body segment. http://purl.obolibrary.org/obo/CL_1000385 type 2 vestibular sensory cell of epithelium of crista of ampulla of semicircular duct of membranous labyrinth http://purl.obolibrary.org/obo/CL_3000004 peripheral sensory neuron A type II vestibular sensory cell that is part of the epithelium of crista of ampulla of semicircular duct of membranous labyrinth. http://purl.obolibrary.org/obo/CL_1000391 melanocyte of eyelid http://purl.obolibrary.org/obo/CL_0000148 melanocyte A melanocyte that is part of the eyelid. http://purl.obolibrary.org/obo/GO_0032836 glomerular basement membrane development http://purl.obolibrary.org/obo/GO_0030198 extracellular matrix organization The process whose specific outcome is the progression of the glomerular basement membrane over time, from its formation to the mature structure. The glomerular basement membrane is the basal laminal portion of the glomerulus which performs the actual filtration. http://purl.obolibrary.org/obo/CL_1000394 myoepithelial cell of intralobular lactiferous duct http://purl.obolibrary.org/obo/CL_0000185 myoepithelial cell A myoepithelial cell that is part of the intralobular part of terminal lactiferous duct. http://purl.obolibrary.org/obo/CL_1000397 endothelial cell of venous sinus of red pulp of spleen http://purl.obolibrary.org/obo/CL_2000053 splenic endothelial cell An endothelial cell that is part of the venous sinus of red pulp of spleen. http://purl.obolibrary.org/obo/GO_0032839 dendrite cytoplasm http://purl.obolibrary.org/obo/GO_0120111 neuron projection cytoplasm All of the contents of a dendrite, excluding the surrounding plasma membrane. http://purl.obolibrary.org/obo/CL_1000398 endothelial cell of hepatic sinusoid http://purl.obolibrary.org/obo/CL_0002262 endothelial cell of sinusoid An endothelial cell that is part of the hepatic sinusoid. These cells possess flattened areas containing perforations about 0.1 micrometers in diameter, known as fenestrae. The fenestrae are arranged in groups known as sieve plates. http://purl.obolibrary.org/obo/CL_1000405 epithelial cell of appendix http://purl.obolibrary.org/obo/CL_0002253 epithelial cell of large intestine An epithelial cell that is part of the appendix. http://purl.obolibrary.org/obo/GO_0032868 response to insulin http://purl.obolibrary.org/obo/GO_0043434 response to peptide hormone Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms. http://purl.obolibrary.org/obo/CL_1000409 myocyte of sinoatrial node http://purl.obolibrary.org/obo/CL_0008009 transversely striated visceral muscle cell A muscle cell that is part of the sinoatrial node. http://purl.obolibrary.org/obo/CL_1000410 myocyte of atrioventricular node http://purl.obolibrary.org/obo/CL_2000022 cardiac septum cell A muscle cell that is part of the atrioventricular node. http://purl.obolibrary.org/obo/GO_0032871 regulation of karyogamy http://purl.obolibrary.org/obo/GO_1903353 regulation of nucleus organization Any process that modulates the frequency, rate or extent of karyogamy, the creation of a single nucleus from multiple nuclei as a result of membrane fusion. http://purl.obolibrary.org/obo/CL_1000411 endothelial cell of Peyer's patch http://purl.obolibrary.org/obo/CL_0000131 gut endothelial cell An endothelial cell that is part of the small intestine Peyer's patch. http://purl.obolibrary.org/obo/GO_0032878 regulation of establishment or maintenance of cell polarity http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns. http://purl.obolibrary.org/obo/CL_1000412 endothelial cell of arteriole http://purl.obolibrary.org/obo/CL_0000071 blood vessel endothelial cell An endothelial cell that is part of the arteriole. http://purl.obolibrary.org/obo/CL_1000413 endothelial cell of artery http://purl.obolibrary.org/obo/CL_0000071 blood vessel endothelial cell A blood vessel endothelial cell that is part of an arterial endothelium. http://purl.obolibrary.org/obo/GO_0032880 regulation of protein localization http://purl.obolibrary.org/obo/GO_0032879 regulation of localization Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location. http://purl.obolibrary.org/obo/CL_1000414 endothelial cell of venule http://purl.obolibrary.org/obo/CL_0000071 blood vessel endothelial cell An endothelial cell that is part of the venule. http://purl.obolibrary.org/obo/CL_1000415 epithelial cell of gallbladder http://purl.obolibrary.org/obo/CL_0000066 epithelial cell An epithelial cell that is part of the gallbladder. http://purl.obolibrary.org/obo/GO_0032881 regulation of polysaccharide metabolic process http://purl.obolibrary.org/obo/GO_0060255 regulation of macromolecule metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving polysaccharides. http://purl.obolibrary.org/obo/CL_1000417 myoepithelial cell of sweat gland http://purl.obolibrary.org/obo/CL_1000448 epithelial cell of sweat gland A myoepithelial cell that is part of the sweat gland. http://purl.obolibrary.org/obo/CL_1000418 myoepithelial cell of lactiferous alveolus http://purl.obolibrary.org/obo/CL_0002324 basal-myoepithelial cell of mammary gland A myoepithelial cell that is part of the mammary gland alveolus. http://purl.obolibrary.org/obo/GO_0032886 regulation of microtubule-based process http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the microtubule cytoskeleton. http://purl.obolibrary.org/obo/CL_1000419 myoepithelial cell of lactiferous duct http://purl.obolibrary.org/obo/CL_0002324 basal-myoepithelial cell of mammary gland A myoepithelial cell that is part of the lactiferous duct. http://purl.obolibrary.org/obo/GO_0032890 regulation of organic acid transport http://purl.obolibrary.org/obo/GO_0051049 regulation of transport Any process that modulates the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/CL_1000420 myoepithelial cell of terminal lactiferous duct http://purl.obolibrary.org/obo/CL_0000185 myoepithelial cell A myoepithelial cell that is part of the terminal lactiferous duct. http://purl.obolibrary.org/obo/GO_0032891 negative regulation of organic acid transport http://purl.obolibrary.org/obo/GO_0051051 negative regulation of transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/CL_1000424 chromaffin cell of paraaortic body http://purl.obolibrary.org/obo/CL_1000425 chromaffin cell of paraganglion A chromaffin cell that is part of the paraaortic body. http://purl.obolibrary.org/obo/CL_1000425 chromaffin cell of paraganglion http://purl.obolibrary.org/obo/CL_0000166 chromaffin cell A chromaffin cell that is part of the paraganglion. http://purl.obolibrary.org/obo/GO_0032892 positive regulation of organic acid transport http://purl.obolibrary.org/obo/GO_0051050 positive regulation of transport Any process that activates or increases the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/CL_1000426 chromaffin cell of adrenal gland http://purl.obolibrary.org/obo/CL_0000166 chromaffin cell A chromaffin cell that is part of the adrenal gland. http://purl.obolibrary.org/obo/GO_0032928 regulation of superoxide anion generation http://purl.obolibrary.org/obo/GO_0090322 regulation of superoxide metabolic process Any process that modulates the frequency, rate or extent of enzymatic generation of superoxide by a cell. http://purl.obolibrary.org/obo/CL_1000427 adrenal cortex chromaffin cell http://purl.obolibrary.org/obo/CL_1001601 adrenal gland glandular cell A chromaffin cell that is part of the adrenal cortex. http://purl.obolibrary.org/obo/CL_1000428 stem cell of epidermis http://purl.obolibrary.org/obo/CL_0000723 somatic stem cell A somatic stem cell that is part of the epidermis. http://purl.obolibrary.org/obo/GO_0032929 negative regulation of superoxide anion generation http://purl.obolibrary.org/obo/GO_2000378 negative regulation of reactive oxygen species metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of enzymatic generation of superoxide by a cell. http://purl.obolibrary.org/obo/CL_1000432 conjunctival epithelial cell http://purl.obolibrary.org/obo/CL_0000066 epithelial cell An epithelial cell that is part of the conjunctiva. http://purl.obolibrary.org/obo/GO_0032930 positive regulation of superoxide anion generation http://purl.obolibrary.org/obo/GO_2000379 positive regulation of reactive oxygen species metabolic process Any process that activates or increases the frequency, rate or extent of enzymatic generation of superoxide by a cell. http://purl.obolibrary.org/obo/CL_1000433 epithelial cell of lacrimal canaliculus http://purl.obolibrary.org/obo/CL_0000066 epithelial cell An epithelial cell that is part of the lacrimal canaliculus. http://purl.obolibrary.org/obo/GO_0032938 negative regulation of translation in response to oxidative stress http://purl.obolibrary.org/obo/GO_0043558 regulation of translational initiation in response to stress Any process that stops, prevents, or reduces the frequency, rate or extent of translation as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals. http://purl.obolibrary.org/obo/CL_1000434 epithelial cell of external acoustic meatus http://purl.obolibrary.org/obo/CL_0000066 epithelial cell An epithelial cell that is part of the external acoustic meatus. http://purl.obolibrary.org/obo/CL_1000435 epithelial cell of lacrimal drainage system http://purl.obolibrary.org/obo/CL_0000072 non-branched duct epithelial cell An epithelial cell that is part of the lacrimal drainage system. http://purl.obolibrary.org/obo/GO_0032939 positive regulation of translation in response to oxidative stress http://purl.obolibrary.org/obo/GO_0032056 positive regulation of translation in response to stress Any process that activates or increases the frequency, rate or extent of translation as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals. http://purl.obolibrary.org/obo/CL_1000436 epithelial cell of lacrimal sac http://purl.obolibrary.org/obo/CL_1000437 epithelial cell of nasolacrimal duct An epithelial cell that is part of the lacrimal sac. http://purl.obolibrary.org/obo/GO_0032941 secretion by tissue http://purl.obolibrary.org/obo/GO_0046903 secretion The controlled release of a substance by a tissue. http://purl.obolibrary.org/obo/CL_1000437 epithelial cell of nasolacrimal duct http://purl.obolibrary.org/obo/CL_1000435 epithelial cell of lacrimal drainage system An epithelial cell that is part of the nasolacrimal duct. http://purl.obolibrary.org/obo/GO_0032943 mononuclear cell proliferation http://purl.obolibrary.org/obo/GO_0070661 leukocyte proliferation The expansion of a mononuclear cell population by cell division. A mononuclear cell is a leukocyte with a single non-segmented nucleus in the mature form. http://purl.obolibrary.org/obo/CL_1000438 epithelial cell of wall of inferior part of anal canal http://purl.obolibrary.org/obo/CL_0002634 epithelial cell of anal column An epithelial cell that is part of the wall of inferior part of anal canal. http://purl.obolibrary.org/obo/GO_0032944 regulation of mononuclear cell proliferation http://purl.obolibrary.org/obo/GO_0070663 regulation of leukocyte proliferation Any process that modulates the frequency, rate or extent of mononuclear cell proliferation. http://purl.obolibrary.org/obo/CL_1000441 epithelial cell of viscerocranial mucosa http://purl.obolibrary.org/obo/CL_0000066 epithelial cell An epithelial cell that is part of the viscerocranial mucosa. http://purl.obolibrary.org/obo/CL_1000442 urothelial cell of trigone of urinary bladder http://purl.obolibrary.org/obo/CL_1001428 bladder urothelial cell An urothelial cell that is part of the trigone of urinary bladder. http://purl.obolibrary.org/obo/GO_0032945 negative regulation of mononuclear cell proliferation http://purl.obolibrary.org/obo/GO_0070664 negative regulation of leukocyte proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of mononuclear cell proliferation. http://purl.obolibrary.org/obo/CL_1000443 ciliary muscle cell http://purl.obolibrary.org/obo/CL_0000192 smooth muscle cell A smooth muscle cell that is part of the ciliary body. http://purl.obolibrary.org/obo/GO_0032946 positive regulation of mononuclear cell proliferation http://purl.obolibrary.org/obo/GO_0070665 positive regulation of leukocyte proliferation Any process that activates or increases the frequency, rate or extent of mononuclear cell proliferation. http://purl.obolibrary.org/obo/CL_1000444 mesothelial cell of anterior chamber of eye http://purl.obolibrary.org/obo/CL_0000077 mesothelial cell A mesothelial cell that is part of the anterior chamber of eyeball. http://purl.obolibrary.org/obo/GO_0032956 regulation of actin cytoskeleton organization http://purl.obolibrary.org/obo/GO_0032970 regulation of actin filament-based process Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins. http://purl.obolibrary.org/obo/CL_1000445 myoepithelial cell of dilator pupillae http://purl.obolibrary.org/obo/CL_0000185 myoepithelial cell A myoepithelial cell that is part of the dilatator pupillae. http://purl.obolibrary.org/obo/GO_0032964 collagen biosynthetic process http://purl.obolibrary.org/obo/GO_0032963 collagen metabolic process The chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%). http://purl.obolibrary.org/obo/CL_1000447 epithelial cell of stratum germinativum of esophagus http://purl.obolibrary.org/obo/CL_0000646 basal cell A basal cell that is part of the epithelium of esophagus. http://purl.obolibrary.org/obo/CL_1000448 epithelial cell of sweat gland http://purl.obolibrary.org/obo/CL_0002308 epithelial cell of skin gland An epithelial cell that is part of the sweat gland. http://purl.obolibrary.org/obo/GO_0032965 regulation of collagen biosynthetic process http://purl.obolibrary.org/obo/GO_0010712 regulation of collagen metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. http://purl.obolibrary.org/obo/CL_1000449 epithelial cell of nephron http://purl.obolibrary.org/obo/CL_0002518 kidney epithelial cell An epithelial cell that is part of the nephron. http://purl.obolibrary.org/obo/GO_0032966 negative regulation of collagen biosynthetic process http://purl.obolibrary.org/obo/GO_0010713 negative regulation of collagen metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. http://purl.obolibrary.org/obo/CL_1000450 epithelial cell of glomerular capsule http://purl.obolibrary.org/obo/CL_1000510 kidney glomerular epithelial cell An epithelial cell that is part of the glomerular capsule. http://purl.obolibrary.org/obo/CL_1000452 parietal epithelial cell http://purl.obolibrary.org/obo/CL_1000450 epithelial cell of glomerular capsule An epithelial cell that is part of the glomerular parietal epithelium. http://purl.obolibrary.org/obo/GO_0032967 positive regulation of collagen biosynthetic process http://purl.obolibrary.org/obo/GO_0010714 positive regulation of collagen metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. http://purl.obolibrary.org/obo/CL_1000453 epithelial cell of intermediate tubule http://purl.obolibrary.org/obo/CL_1000909 kidney loop of Henle epithelial cell An epithelial cell that is part of the intermediate tubule. http://purl.obolibrary.org/obo/CL_1000454 kidney collecting duct epithelial cell http://purl.obolibrary.org/obo/CL_1001225 kidney collecting duct cell An epithelial cell that is part of the collecting duct of renal tubule. http://purl.obolibrary.org/obo/GO_0032970 regulation of actin filament-based process http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the actin cytoskeleton. http://purl.obolibrary.org/obo/CL_1000456 mesothelial cell of parietal peritoneum http://purl.obolibrary.org/obo/CL_1000490 mesothelial cell of peritoneum A mesothelial cell that is part of the parietal peritoneum. http://purl.obolibrary.org/obo/GO_0032973 amino acid export across plasma membrane http://purl.obolibrary.org/obo/GO_0140115 export across plasma membrane The directed movement of amino acids from inside of a cell, across the plasma membrane and into the extracellular region. http://purl.obolibrary.org/obo/CL_1000457 mesothelial cell of visceral peritoneum http://purl.obolibrary.org/obo/CL_1000490 mesothelial cell of peritoneum A mesothelial cell that is part of the visceral peritoneum. http://purl.obolibrary.org/obo/GO_0032974 amino acid transmembrane export from vacuole http://purl.obolibrary.org/obo/GO_0034486 vacuolar transmembrane transport The directed movement of amino acids out of the vacuole, across the vacuolar membrane. http://purl.obolibrary.org/obo/CL_1000458 melanocyte of skin http://purl.obolibrary.org/obo/CL_0000148 melanocyte A melanocyte that is part of the skin of body. http://purl.obolibrary.org/obo/GO_0032975 amino acid transmembrane import into vacuole http://purl.obolibrary.org/obo/GO_0034486 vacuolar transmembrane transport The directed movement of amino acids into the vacuole across the vacuolar membrane. http://purl.obolibrary.org/obo/GO_0032980 keratinocyte activation http://purl.obolibrary.org/obo/GO_0001775 cell activation A change in the morphology or behavior of a keratinocyte resulting from exposure to an activating factor such as a cellular or soluble ligand. Upon activation, keratinocytes become migratory and hyperproliferative, and produce growth factors and cytokines. http://purl.obolibrary.org/obo/CL_1000465 chromaffin cell of ovary http://purl.obolibrary.org/obo/CL_0000166 chromaffin cell A chromaffin cell that is part of the ovary. http://purl.obolibrary.org/obo/CL_1000466 chromaffin cell of right ovary http://purl.obolibrary.org/obo/CL_1000465 chromaffin cell of ovary A chromaffin cell that is part of the right ovary. http://purl.obolibrary.org/obo/GO_0032983 kainate selective glutamate receptor complex http://purl.obolibrary.org/obo/GO_0008328 ionotropic glutamate receptor complex An assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex. Kainate receptors are multimeric assemblies of GluK1-3 (also called GluR5-7), GluK4 (KA1) and GluK5 (KA2) subunits. http://purl.obolibrary.org/obo/CL_1000467 chromaffin cell of left ovary http://purl.obolibrary.org/obo/CL_1000465 chromaffin cell of ovary A chromaffin cell that is part of the left ovary. http://purl.obolibrary.org/obo/CL_1000468 myoepithelial cell of acinus of lactiferous gland http://purl.obolibrary.org/obo/CL_0002324 basal-myoepithelial cell of mammary gland A myoepithelial cell that is part of the acinus of lactiferous gland. http://purl.obolibrary.org/obo/GO_0032987 protein-lipid complex disassembly http://purl.obolibrary.org/obo/GO_0071825 protein-lipid complex organization The disaggregation of a protein-lipid complex into its constituent components. http://purl.obolibrary.org/obo/CL_1000469 myoepithelial cell of main lactiferous duct http://purl.obolibrary.org/obo/CL_0000185 myoepithelial cell A myoepithelial cell that is part of the main lactiferous duct. http://purl.obolibrary.org/obo/CL_1000470 myoepithelial cell of primary lactiferous duct http://purl.obolibrary.org/obo/CL_0000185 myoepithelial cell A myoepithelial cell that is part of the primary lactiferous duct. http://purl.obolibrary.org/obo/GO_0032994 protein-lipid complex http://purl.obolibrary.org/obo/GO_0032991 protein-containing complex A macromolecular complex containing separate protein and lipid molecules. Separate in this context means not covalently bound to each other. http://purl.obolibrary.org/obo/CL_1000471 myoepithelial cell of secondary lactiferous duct http://purl.obolibrary.org/obo/CL_0000185 myoepithelial cell A myoepithelial cell that is part of the secondary lactiferous duct. http://purl.obolibrary.org/obo/GO_0032997 Fc receptor complex http://purl.obolibrary.org/obo/GO_0098797 plasma membrane protein complex A protein complex composed of a subunit or subunits capable of binding the Fc portion of an immunoglobulin with additional signaling components. The complex functions as a receptor for immunoglobulin. http://purl.obolibrary.org/obo/CL_1000472 myoepithelial cell of tertiary lactiferous duct http://purl.obolibrary.org/obo/CL_0000185 myoepithelial cell A myoepithelial cell that is part of the tertiary lactiferous duct. http://purl.obolibrary.org/obo/GO_0033001 Fc-gamma receptor III complex http://purl.obolibrary.org/obo/GO_0032997 Fc receptor complex A protein complex composed of an Fc-gamma RIII alpha chain and an Fc-epsilon RI gamma chain dimer with or without an Fc-epsilon RI beta chain and additional signaling components. The complex functions primarily as an activating receptor for IgG. http://purl.obolibrary.org/obo/CL_1000473 myoepithelial cell of quarternary lactiferous duct http://purl.obolibrary.org/obo/CL_0000185 myoepithelial cell A myoepithelial cell that is part of the quarternary lactiferous duct. http://purl.obolibrary.org/obo/GO_0033003 regulation of mast cell activation http://purl.obolibrary.org/obo/GO_0002694 regulation of leukocyte activation Any process that modulates the frequency, rate, or extent of mast cell activation. http://purl.obolibrary.org/obo/CL_1000477 cardiac pacemaker cell of sinoatrial node http://purl.obolibrary.org/obo/CL_1000409 myocyte of sinoatrial node A nodal myocyte that is part of the sinoatrial node. http://purl.obolibrary.org/obo/GO_0033004 negative regulation of mast cell activation http://purl.obolibrary.org/obo/GO_0033003 regulation of mast cell activation Any process that stops, prevents, or reduces the frequency, rate, or extent of mast cell activation. http://purl.obolibrary.org/obo/CL_1000478 transitional myocyte of sinoatrial node http://purl.obolibrary.org/obo/CL_1000409 myocyte of sinoatrial node A transitional myocyte that is part of the sinoatrial node. http://purl.obolibrary.org/obo/GO_0033005 positive regulation of mast cell activation http://purl.obolibrary.org/obo/GO_0033003 regulation of mast cell activation Any process that activates or increases the frequency, rate, or extent of mast cell activation. http://purl.obolibrary.org/obo/CL_1000479 Purkinje myocyte of atrioventricular node http://purl.obolibrary.org/obo/CL_1000410 myocyte of atrioventricular node A Purkinje myocyte that is part of the atrioventricular node. http://purl.obolibrary.org/obo/CL_1000480 transitional myocyte of internodal tract http://purl.obolibrary.org/obo/CL_0002096 internodal tract myocyte A transitional myocyte that is part of the internodal tract. http://purl.obolibrary.org/obo/GO_0033007 negative regulation of mast cell activation involved in immune response http://purl.obolibrary.org/obo/GO_0033004 negative regulation of mast cell activation Any process that stops, prevents, or reduces the frequency, rate, or extent of mast cell activation as part of an immune response. http://purl.obolibrary.org/obo/CL_1000481 transitional myocyte of atrioventricular bundle http://purl.obolibrary.org/obo/CL_2000046 ventricular cardiac muscle cell A transitional myocyte that is part of the atrioventricular bundle. http://purl.obolibrary.org/obo/GO_0033008 positive regulation of mast cell activation involved in immune response http://purl.obolibrary.org/obo/GO_0033005 positive regulation of mast cell activation Any process that activates or increases the frequency, rate, or extent of mast cell activation as part of an immune response. http://purl.obolibrary.org/obo/CL_1000482 myocardial endocrine cell of interventricular septum http://purl.obolibrary.org/obo/CL_2000022 cardiac septum cell A myocardial endocrine cell that is part of the interventricular septum. http://purl.obolibrary.org/obo/GO_0033023 mast cell homeostasis http://purl.obolibrary.org/obo/GO_0002262 myeloid cell homeostasis The process of regulating the proliferation and elimination of mast cells such that the total number of mast cells within a whole or part of an organism is stable over time in the absence of an outside stimulus. http://purl.obolibrary.org/obo/CL_1000483 Purkinje myocyte of internodal tract http://purl.obolibrary.org/obo/CL_0002096 internodal tract myocyte A Purkinje myocyte that is part of the internodal tract. http://purl.obolibrary.org/obo/GO_0033024 mast cell apoptotic process http://purl.obolibrary.org/obo/GO_0071887 leukocyte apoptotic process Any apoptotic process in a mast cell, a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation. http://purl.obolibrary.org/obo/CL_1000484 Purkinje myocyte of atrioventricular bundle http://purl.obolibrary.org/obo/CL_2000046 ventricular cardiac muscle cell A Purkinje myocyte that is part of the atrioventricular bundle. http://purl.obolibrary.org/obo/GO_0033025 regulation of mast cell apoptotic process http://purl.obolibrary.org/obo/GO_2000106 regulation of leukocyte apoptotic process Any process that modulates the frequency, rate, or extent of mast cell apoptotic process. http://purl.obolibrary.org/obo/CL_1000486 basal cell of urothelium http://purl.obolibrary.org/obo/CL_0011026 progenitor cell A basal cell that is part of the urothelium. Compared to other urothelial cell types, a basal cell of the urothelium is positioned along the basement membrane, is the most undifferentiated and serves a progenitor role. http://purl.obolibrary.org/obo/GO_0033026 negative regulation of mast cell apoptotic process http://purl.obolibrary.org/obo/GO_2000107 negative regulation of leukocyte apoptotic process Any process that stops, prevents, or reduces the frequency, rate, or extent of mast cell apoptotic process. http://purl.obolibrary.org/obo/CL_1000487 smooth muscle cell of prostate http://purl.obolibrary.org/obo/CL_0000192 smooth muscle cell A smooth muscle cell that is part of the prostate gland. http://purl.obolibrary.org/obo/GO_0033027 positive regulation of mast cell apoptotic process http://purl.obolibrary.org/obo/GO_2000108 positive regulation of leukocyte apoptotic process Any process that activates or increases the frequency, rate, or extent of mast cell apoptotic process. http://purl.obolibrary.org/obo/CL_1000488 cholangiocyte http://purl.obolibrary.org/obo/CL_0000069 branched duct epithelial cell An epithelial cell that is part of the bile duct. Cholangiocytes contribute to bile secretion via net release of bicarbonate and water. They are cuboidal epithelium in the small interlobular bile ducts, but become columnar and mucus secreting in larger bile ducts approaching the porta hepatis and the extrahepatic ducts. http://purl.obolibrary.org/obo/GO_0033029 regulation of neutrophil apoptotic process http://purl.obolibrary.org/obo/GO_2000106 regulation of leukocyte apoptotic process Any process that modulates the frequency, rate, or extent of neutrophil apoptotic process. http://purl.obolibrary.org/obo/GO_0033030 negative regulation of neutrophil apoptotic process http://purl.obolibrary.org/obo/GO_2000107 negative regulation of leukocyte apoptotic process Any process that stops, prevents, or reduces the frequency, rate, or extent of neutrophil apoptotic process. http://purl.obolibrary.org/obo/CL_1000489 reticular cell of splenic cord http://purl.obolibrary.org/obo/CL_2000051 splenic fibroblast A reticular cell that is part of the splenic cord. http://purl.obolibrary.org/obo/GO_0033031 positive regulation of neutrophil apoptotic process http://purl.obolibrary.org/obo/GO_2000108 positive regulation of leukocyte apoptotic process Any process that activates or increases the frequency, rate, or extent of neutrophil apoptotic process. http://purl.obolibrary.org/obo/CL_1000490 mesothelial cell of peritoneum http://purl.obolibrary.org/obo/CL_0000077 mesothelial cell A mesothelial cell that is part of the peritoneum. http://purl.obolibrary.org/obo/CL_1000491 mesothelial cell of pleura http://purl.obolibrary.org/obo/CL_0000077 mesothelial cell A mesothelial cell that is part of the pleura. http://purl.obolibrary.org/obo/GO_0033032 regulation of myeloid cell apoptotic process http://purl.obolibrary.org/obo/GO_0042981 regulation of apoptotic process Any process that modulates the frequency, rate, or extent of myeloid cell apoptotic process. http://purl.obolibrary.org/obo/CL_1000492 mesothelial cell of parietal pleura http://purl.obolibrary.org/obo/CL_1000491 mesothelial cell of pleura A mesothelial cell that is part of the parietal pleura. http://purl.obolibrary.org/obo/GO_0033033 negative regulation of myeloid cell apoptotic process http://purl.obolibrary.org/obo/GO_0033032 regulation of myeloid cell apoptotic process Any process that stops, prevents, or reduces the frequency, rate, or extent of a myeloid cell apoptotic process. http://purl.obolibrary.org/obo/CL_1000493 mesothelial cell of visceral pleura http://purl.obolibrary.org/obo/CL_1000491 mesothelial cell of pleura A mesothelial cell that is part of the visceral pleura. http://purl.obolibrary.org/obo/GO_0033034 positive regulation of myeloid cell apoptotic process http://purl.obolibrary.org/obo/GO_0043065 positive regulation of apoptotic process Any process that activates or increases the frequency, rate, or extent of myeloid cell apoptotic process. http://purl.obolibrary.org/obo/CL_1000494 nephron tubule epithelial cell http://purl.obolibrary.org/obo/CL_1000507 kidney tubule cell An epithelial cell that is part of a nephron tubule. http://purl.obolibrary.org/obo/GO_0033044 regulation of chromosome organization http://purl.obolibrary.org/obo/GO_0033043 regulation of organelle organization Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a chromosome. http://purl.obolibrary.org/obo/CL_1000495 small intestine goblet cell http://purl.obolibrary.org/obo/CL_1001598 small intestine secretory cell A goblet cell that is part of the small intestine. http://purl.obolibrary.org/obo/GO_0033046 negative regulation of sister chromatid segregation http://purl.obolibrary.org/obo/GO_2001251 negative regulation of chromosome organization Any process that stops, prevents, or reduces the frequency, rate or extent of sister chromatid segregation. http://purl.obolibrary.org/obo/CL_1000497 kidney cell http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell A cell that is part of a kidney. http://purl.obolibrary.org/obo/GO_0033048 negative regulation of mitotic sister chromatid segregation http://purl.obolibrary.org/obo/GO_0033047 regulation of mitotic sister chromatid segregation Any process that stops, prevents, or reduces the frequency, rate or extent of sister chromatid segregation during mitosis. http://purl.obolibrary.org/obo/CL_1000500 kidney interstitial cell http://purl.obolibrary.org/obo/CL_1000497 kidney cell A cell that is part of kidney interstitium. http://purl.obolibrary.org/obo/CL_1000504 kidney medulla cell http://purl.obolibrary.org/obo/CL_1000497 kidney cell A cell that is part of a renal medulla. http://purl.obolibrary.org/obo/GO_0033059 cellular pigmentation http://purl.obolibrary.org/obo/GO_0043473 pigmentation The deposition or aggregation of coloring matter in a cell. http://purl.obolibrary.org/obo/CL_1000505 kidney pelvis cell http://purl.obolibrary.org/obo/CL_1000497 kidney cell A cell that is part of a renal pelvis. http://purl.obolibrary.org/obo/GO_0033077 T cell differentiation in thymus http://purl.obolibrary.org/obo/GO_0030217 T cell differentiation The process in which a precursor cell type acquires the specialized features of a T cell via a differentiation pathway dependent upon transit through the thymus. http://purl.obolibrary.org/obo/CL_1000507 kidney tubule cell http://purl.obolibrary.org/obo/CL_1000497 kidney cell A cell that is part of a nephron tubule. http://purl.obolibrary.org/obo/GO_0033079 immature T cell proliferation http://purl.obolibrary.org/obo/GO_0042098 T cell proliferation The expansion of an immature T cell population by cell division. http://purl.obolibrary.org/obo/CL_1000510 kidney glomerular epithelial cell http://purl.obolibrary.org/obo/CL_1000746 glomerular cell Any kidney epithelial cell that is part of some glomerular epithelium. http://purl.obolibrary.org/obo/GO_0033080 immature T cell proliferation in thymus http://purl.obolibrary.org/obo/GO_0033079 immature T cell proliferation The expansion of an immature T cell population by cell division in the thymus. http://purl.obolibrary.org/obo/CL_1000546 kidney medulla collecting duct epithelial cell http://purl.obolibrary.org/obo/CL_1000504 kidney medulla cell An epithelial cell that is part of a renal medulla collecting duct. http://purl.obolibrary.org/obo/GO_0033081 regulation of T cell differentiation in thymus http://purl.obolibrary.org/obo/GO_0045580 regulation of T cell differentiation Any process that modulates the frequency, rate or extent of T cell differentiation in the thymus. http://purl.obolibrary.org/obo/CL_1000547 kidney inner medulla collecting duct epithelial cell http://purl.obolibrary.org/obo/CL_1000617 kidney inner medulla cell An epithelial cell that is part of some inner medullary collecting duct. http://purl.obolibrary.org/obo/GO_0033083 regulation of immature T cell proliferation http://purl.obolibrary.org/obo/GO_0042129 regulation of T cell proliferation Any process that modulates the frequency, rate or extent of immature T cell proliferation. http://purl.obolibrary.org/obo/CL_1000548 kidney outer medulla collecting duct epithelial cell http://purl.obolibrary.org/obo/CL_1000616 kidney outer medulla cell An epithelial cell that is part of an outer medullary collecting duct. http://purl.obolibrary.org/obo/GO_0033084 regulation of immature T cell proliferation in thymus http://purl.obolibrary.org/obo/GO_0033083 regulation of immature T cell proliferation Any process that modulates the frequency, rate or extent of immature T cell proliferation in the thymus. http://purl.obolibrary.org/obo/CL_1000549 kidney cortex collecting duct epithelial cell http://purl.obolibrary.org/obo/CL_1000454 kidney collecting duct epithelial cell An epithelial cell that is part of a cortical collecting duct. http://purl.obolibrary.org/obo/GO_0033085 negative regulation of T cell differentiation in thymus http://purl.obolibrary.org/obo/GO_0045581 negative regulation of T cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of T cell differentiation in the thymus. http://purl.obolibrary.org/obo/CL_1000550 kidney papillary duct principal epithelial cell http://purl.obolibrary.org/obo/CL_1001225 kidney collecting duct cell Any kidney cell that is part of some papillary duct. http://purl.obolibrary.org/obo/GO_0033087 negative regulation of immature T cell proliferation http://purl.obolibrary.org/obo/GO_0042130 negative regulation of T cell proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of immature T cell proliferation. http://purl.obolibrary.org/obo/CL_1000596 inner renal cortex cell http://purl.obolibrary.org/obo/CL_0002681 kidney cortical cell Any kidney cell that is part of some juxtamedullary cortex. http://purl.obolibrary.org/obo/GO_0033088 negative regulation of immature T cell proliferation in thymus http://purl.obolibrary.org/obo/GO_0033087 negative regulation of immature T cell proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of immature T cell proliferation in the thymus. http://purl.obolibrary.org/obo/CL_1000597 papillary tips cell http://purl.obolibrary.org/obo/CL_1000617 kidney inner medulla cell A cell that is part of a tip of a renal papilla. http://purl.obolibrary.org/obo/GO_0033089 positive regulation of T cell differentiation in thymus http://purl.obolibrary.org/obo/GO_0045582 positive regulation of T cell differentiation Any process that activates or increases the frequency, rate or extent of T cell differentiation in the thymus. http://purl.obolibrary.org/obo/CL_1000600 lower urinary tract cell http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell Any cell that is part of some lower urinary tract. http://purl.obolibrary.org/obo/GO_0033091 positive regulation of immature T cell proliferation http://purl.obolibrary.org/obo/GO_0042102 positive regulation of T cell proliferation Any process that activates or increases the frequency, rate or extent of immature T cell proliferation. http://purl.obolibrary.org/obo/CL_1000601 ureteral cell http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell Any cell that is part of some ureter. http://purl.obolibrary.org/obo/CL_1000606 kidney nerve cell http://purl.obolibrary.org/obo/CL_2000032 peripheral nervous system neuron Any neuron that has its soma located in some kidney. http://purl.obolibrary.org/obo/GO_0033092 positive regulation of immature T cell proliferation in thymus http://purl.obolibrary.org/obo/GO_0033091 positive regulation of immature T cell proliferation Any process that activates or increases the frequency, rate or extent of immature T cell proliferation in the thymus. http://purl.obolibrary.org/obo/CL_1000612 kidney corpuscule cell http://purl.obolibrary.org/obo/CL_1000449 epithelial cell of nephron Any renal cortical epithelial cell that is part of some renal corpuscle. http://purl.obolibrary.org/obo/GO_0033093 Weibel-Palade body http://purl.obolibrary.org/obo/GO_0030136 clathrin-coated vesicle A large, elongated, rod-shaped secretory granule characteristic of vascular endothelial cells that contain a number of structurally and functionally distinct proteins, of which the best characterized are von Willebrand factor (VWF) and P-selectin. Weibel-Palade bodies are formed from the trans-Golgi network in a process that depends on VWF, which is densely packed in a highly organized manner, and on coat proteins that remain associated with the granules. Upon cell stimulation, regulated exocytosis releases the contained proteins to the cell surface, where they act in the recruitment of platelets and leukocytes and in inflammatory and vasoactive responses. http://purl.obolibrary.org/obo/CL_1000615 kidney cortex tubule cell http://purl.obolibrary.org/obo/CL_1000507 kidney tubule cell Any kidney tubule cell that is part of some renal cortex tubule. http://purl.obolibrary.org/obo/CL_1000616 kidney outer medulla cell http://purl.obolibrary.org/obo/CL_1000504 kidney medulla cell Any kidney medulla cell that is part of some outer medulla of kidney. http://purl.obolibrary.org/obo/GO_0033121 regulation of purine nucleotide catabolic process http://purl.obolibrary.org/obo/GO_1900542 regulation of purine nucleotide metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of purine nucleotides. http://purl.obolibrary.org/obo/CL_1000617 kidney inner medulla cell http://purl.obolibrary.org/obo/CL_1000504 kidney medulla cell Any kidney medulla cell that is part of some inner medulla of kidney. http://purl.obolibrary.org/obo/GO_0033122 negative regulation of purine nucleotide catabolic process http://purl.obolibrary.org/obo/GO_1900543 negative regulation of purine nucleotide metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of purine nucleotides. http://purl.obolibrary.org/obo/CL_1000618 juxtaglomerular complex cell http://purl.obolibrary.org/obo/CL_0002681 kidney cortical cell Any kidney cortical cell that is part of some juxtaglomerular apparatus. http://purl.obolibrary.org/obo/GO_0033123 positive regulation of purine nucleotide catabolic process http://purl.obolibrary.org/obo/GO_1900544 positive regulation of purine nucleotide metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of purine nucleotides. http://purl.obolibrary.org/obo/CL_1000681 kidney cortex interstitial cell http://purl.obolibrary.org/obo/CL_1000500 kidney interstitial cell A cell that is part of an interstitial compartment of a renal cortex. http://purl.obolibrary.org/obo/GO_0033151 V(D)J recombination http://purl.obolibrary.org/obo/GO_0002562 somatic diversification of immune receptors via germline recombination within a single locus The process in which immune receptor V, D, and J, or V and J gene segments, depending on the specific receptor, are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS). http://purl.obolibrary.org/obo/CL_1000682 kidney medulla interstitial cell http://purl.obolibrary.org/obo/CL_1000504 kidney medulla cell A cell that is part of an interstitum of a renal medulla. http://purl.obolibrary.org/obo/GO_0033152 immunoglobulin V(D)J recombination http://purl.obolibrary.org/obo/GO_0033151 V(D)J recombination The process in which immunoglobulin gene segments are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS). For immunoglobulin heavy chains V, D, and J gene segments are joined, and for immunoglobulin light chains V and J gene segments are joined. http://purl.obolibrary.org/obo/CL_1000692 kidney interstitial fibroblast http://purl.obolibrary.org/obo/CL_1000500 kidney interstitial cell A fibroblast that is part of an interstitial compartment of a kidney. http://purl.obolibrary.org/obo/CL_1000693 kidney interstitial fibrocyte http://purl.obolibrary.org/obo/CL_1000500 kidney interstitial cell A stromal cell that infiltrates and resides in the kidney interstitium following injury, characterized by the co-expression of CD45 with mesenchymal markers including α-SMA, and collagen I in humans (Kim et al., 2023). This cell originates from circulating monocyte-derived fibrocytes. It produces extracellular matrix components, contributing to renal fibrosis by potentially differentiating into myofibroblasts upon infiltration into injured kidneys (Sun et al., 2016). Migration into the kidney is dependent on chemokine receptor signaling, particularly CCR2 in mice (Reich et al., 2013). http://purl.obolibrary.org/obo/GO_0033157 regulation of intracellular protein transport http://purl.obolibrary.org/obo/GO_0051223 regulation of protein transport Any process that modulates the frequency, rate or extent of the directed movement of proteins within cells. http://purl.obolibrary.org/obo/CL_1000698 kidney resident macrophage http://purl.obolibrary.org/obo/CL_1000500 kidney interstitial cell A tissue-resident macrophage that is part of some kidney. http://purl.obolibrary.org/obo/GO_0033162 melanosome membrane http://purl.obolibrary.org/obo/GO_0090741 pigment granule membrane The lipid bilayer surrounding a melanosome. http://purl.obolibrary.org/obo/CL_1000699 kidney resident dendritic cell http://purl.obolibrary.org/obo/CL_1000500 kidney interstitial cell A resident-dendritic cell that is part of a kidney. http://purl.obolibrary.org/obo/GO_0033198 response to ATP http://purl.obolibrary.org/obo/GO_0014074 response to purine-containing compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ATP (adenosine 5'-triphosphate) stimulus. http://purl.obolibrary.org/obo/CL_1000702 kidney pelvis smooth muscle cell http://purl.obolibrary.org/obo/CL_1000505 kidney pelvis cell Any smooth muscle cell that is part of some kidney pelvis smooth muscle. http://purl.obolibrary.org/obo/GO_0033212 iron import into cell http://purl.obolibrary.org/obo/GO_0051649 establishment of localization in cell The directed movement of iron ions from outside of a cell into the cytoplasmic compartment. This may occur via transport across the plasma membrane or via endocytosis. http://purl.obolibrary.org/obo/CL_1000703 kidney pelvis urothelial cell http://purl.obolibrary.org/obo/CL_1000505 kidney pelvis cell Any kidney epithelial cell that is part of some kidney pelvis urothelium. http://purl.obolibrary.org/obo/CL_1000706 ureter urothelial cell http://purl.obolibrary.org/obo/CL_1000601 ureteral cell A urothelial cell that is part of the urothelium of ureter. http://purl.obolibrary.org/obo/GO_0033239 negative regulation of amine metabolic process http://purl.obolibrary.org/obo/GO_0009892 negative regulation of metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amines. http://purl.obolibrary.org/obo/CL_1000708 ureter adventitial cell http://purl.obolibrary.org/obo/CL_1000601 ureteral cell Any ureteral cell that is part of some adventitia of ureter. http://purl.obolibrary.org/obo/GO_0033240 positive regulation of amine metabolic process http://purl.obolibrary.org/obo/GO_0009893 positive regulation of metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amines. http://purl.obolibrary.org/obo/CL_1000714 kidney cortex collecting duct principal cell http://purl.obolibrary.org/obo/CL_1001431 kidney collecting duct principal cell Any renal principal cell that is part of some cortical collecting duct. http://purl.obolibrary.org/obo/GO_0033241 regulation of amine catabolic process http://purl.obolibrary.org/obo/GO_0009894 regulation of catabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines. http://purl.obolibrary.org/obo/CL_1000715 kidney cortex collecting duct intercalated cell http://purl.obolibrary.org/obo/CL_1001432 kidney collecting duct intercalated cell Any renal intercalated cell that is part of some cortical collecting duct. http://purl.obolibrary.org/obo/GO_0033242 negative regulation of amine catabolic process http://purl.obolibrary.org/obo/GO_0009895 negative regulation of catabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines. http://purl.obolibrary.org/obo/CL_1000716 kidney outer medulla collecting duct principal cell http://purl.obolibrary.org/obo/CL_1001431 kidney collecting duct principal cell Principal cell that is part of some outer medullary collecting duct. It is known in some mammalian species that this cell may express the epithelial sodium channel (ENaC). http://purl.obolibrary.org/obo/GO_0033243 positive regulation of amine catabolic process http://purl.obolibrary.org/obo/GO_0009896 positive regulation of catabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines. http://purl.obolibrary.org/obo/CL_1000717 kidney outer medulla collecting duct intercalated cell http://purl.obolibrary.org/obo/CL_1001432 kidney collecting duct intercalated cell Intercalated cell that is part of some outer medullary collecting duct. It is known in some mammalian species that this cell may contribute in the maintenance of acid/base homeostasis. http://purl.obolibrary.org/obo/GO_0033278 cell proliferation in midbrain http://purl.obolibrary.org/obo/GO_0061351 neural precursor cell proliferation The multiplication or reproduction of cells, resulting in the expansion of a cell population in the midbrain. http://purl.obolibrary.org/obo/CL_1000718 kidney inner medulla collecting duct principal cell http://purl.obolibrary.org/obo/CL_1001431 kidney collecting duct principal cell Any renal principal cell that is part of some inner medullary collecting duct. http://purl.obolibrary.org/obo/GO_0033326 cerebrospinal fluid secretion http://purl.obolibrary.org/obo/GO_0032941 secretion by tissue The regulated release of cerebrospinal fluid (CSF) from the choroid plexus of the lateral, third and fourth ventricles. The cerebrospinal fluid is a clear liquid that located within the ventricles, spinal canal, and subarachnoid spaces. http://purl.obolibrary.org/obo/CL_1000719 kidney inner medulla collecting duct intercalated cell http://purl.obolibrary.org/obo/CL_1001432 kidney collecting duct intercalated cell Any renal intercalated cell that is part of some inner medullary collecting duct. http://purl.obolibrary.org/obo/GO_0033327 Leydig cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a Leydig cell. A Leydig cell is a testosterone-secreting cell in the interstitial area, between the seminiferous tubules, in the testis. http://purl.obolibrary.org/obo/CL_1000720 kidney papillary duct intercalated cell http://purl.obolibrary.org/obo/CL_1001432 kidney collecting duct intercalated cell Any renal intercalated cell that is part of some papillary duct. http://purl.obolibrary.org/obo/CL_1000721 kidney papillary duct principal cell http://purl.obolibrary.org/obo/CL_1001431 kidney collecting duct principal cell Any renal principal cell that is part of some papillary duct. http://purl.obolibrary.org/obo/GO_0033364 mast cell secretory granule organization http://purl.obolibrary.org/obo/GO_0033363 secretory granule organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule in a mast cell. A secretory granule is a small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. http://purl.obolibrary.org/obo/CL_1000742 glomerular mesangial cell http://purl.obolibrary.org/obo/CL_1000746 glomerular cell A mesangial cell located among the glomerular capillaries in a renal corpuscle. http://purl.obolibrary.org/obo/GO_0033365 protein localization to organelle http://purl.obolibrary.org/obo/GO_0008104 intracellular protein localization A process in which a protein is transported to, or maintained in, a location within an organelle. http://purl.obolibrary.org/obo/CL_1000746 glomerular cell http://purl.obolibrary.org/obo/CL_1000612 kidney corpuscule cell Any kidney corpuscule cell that is part of some renal glomerulus. http://purl.obolibrary.org/obo/GO_0033366 protein localization to secretory granule http://purl.obolibrary.org/obo/GO_0033365 protein localization to organelle A process in which a protein is transported to, or maintained in, a location within a secretory granule. http://purl.obolibrary.org/obo/CL_1000768 kidney connecting tubule epithelial cell http://purl.obolibrary.org/obo/CL_1000615 kidney cortex tubule cell Any nephron tubule epithelial cell that is part of some renal connecting tubule. http://purl.obolibrary.org/obo/CL_1000803 kidney inner medulla interstitial cell http://purl.obolibrary.org/obo/CL_1000682 kidney medulla interstitial cell A cell that is part of an interstitial compartment of an inner renal medulla. http://purl.obolibrary.org/obo/GO_0033371 T cell secretory granule organization http://purl.obolibrary.org/obo/GO_0033363 secretory granule organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule in a T cell. A secretory granule is a small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. http://purl.obolibrary.org/obo/CL_1000804 kidney outer medulla interstitial cell http://purl.obolibrary.org/obo/CL_1000682 kidney medulla interstitial cell A kidney cell that is part of an interstitial compartment of an outer renal medulla. http://purl.obolibrary.org/obo/GO_0033374 protein localization to T cell secretory granule http://purl.obolibrary.org/obo/GO_0033366 protein localization to secretory granule A process in which a protein is transported to, or maintained in, a location within a secretory granule in a T cell. http://purl.obolibrary.org/obo/CL_1000838 kidney proximal convoluted tubule epithelial cell http://purl.obolibrary.org/obo/CL_0002307 brush border cell of the proximal tubule Any epithelial cell of proximal tubule that is part of some proximal convoluted tubule and has part some brush border. http://purl.obolibrary.org/obo/GO_0033375 protease localization to T cell secretory granule http://purl.obolibrary.org/obo/GO_0033374 protein localization to T cell secretory granule Any process in which a protease is transported to, or maintained in, a location within a secretory granule in a T cell. http://purl.obolibrary.org/obo/CL_1000839 kidney proximal straight tubule epithelial cell http://purl.obolibrary.org/obo/CL_1001021 kidney loop of Henle descending limb epithelial cell Any epithelial cell of proximal tubule that is part of some proximal straight tubule. http://purl.obolibrary.org/obo/GO_0033380 granzyme B localization to T cell secretory granule http://purl.obolibrary.org/obo/GO_0033375 protease localization to T cell secretory granule Any process in which the protease granzyme B is transported to, or maintained in, a location within a secretory granule in a T cell. http://purl.obolibrary.org/obo/CL_1000849 kidney distal convoluted tubule epithelial cell http://purl.obolibrary.org/obo/CL_0002305 epithelial cell of distal tubule Any epithelial cell of distal tubule that is part of some distal convoluted tubule. http://purl.obolibrary.org/obo/GO_0033484 intracellular nitric oxide homeostasis http://purl.obolibrary.org/obo/GO_0055082 intracellular chemical homeostasis A homeostatic process involved in the maintenance of a steady state level of nitric oxide within a cell. http://purl.obolibrary.org/obo/CL_1000850 macula densa epithelial cell http://purl.obolibrary.org/obo/CL_1000618 juxtaglomerular complex cell An epithelial cell that is part of the macula densa, characterized by a tightly packed arrangement, apically positioned nuclei, and prominent primary cilia, creating a distinctive 'dense spot' appearance under microscopy. It is involved in regulating renal blood flow, glomerular filtration rate, and renin release. http://purl.obolibrary.org/obo/GO_0033500 carbohydrate homeostasis http://purl.obolibrary.org/obo/GO_0048878 chemical homeostasis A homeostatic process involved in the maintenance of an internal steady state of a carbohydrate within an organism or cell. http://purl.obolibrary.org/obo/CL_1000854 kidney blood vessel cell http://purl.obolibrary.org/obo/CL_1000504 kidney medulla cell A blood vessel cell that is part of a kidney. http://purl.obolibrary.org/obo/GO_0033504 floor plate development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the floor plate over time from its initial formation until its mature state. http://purl.obolibrary.org/obo/CL_1000891 kidney arterial blood vessel cell http://purl.obolibrary.org/obo/CL_1000854 kidney blood vessel cell Any kidney blood vessel cell that is part of some kidney arterial blood vessel. http://purl.obolibrary.org/obo/GO_0033505 floor plate morphogenesis http://purl.obolibrary.org/obo/GO_0048729 tissue morphogenesis The process in which the anatomical structure of the floor plate is generated and organized. http://purl.obolibrary.org/obo/CL_1000892 kidney capillary endothelial cell http://purl.obolibrary.org/obo/CL_1000854 kidney blood vessel cell An endothelial cell that is part of the capillary of the kidney. http://purl.obolibrary.org/obo/GO_0033568 lactoferrin receptor activity http://purl.obolibrary.org/obo/GO_0038024 cargo receptor activity Combining with lactoferrin and delivering lactoferrin into the cell via endocytosis. Lactoferrin is an iron-binding glycoprotein which binds ferric iron most efficiently at low pH. http://purl.obolibrary.org/obo/CL_1000893 kidney venous blood vessel cell http://purl.obolibrary.org/obo/CL_1000854 kidney blood vessel cell Any kidney blood vessel cell that is part of some renal vein. http://purl.obolibrary.org/obo/GO_0033569 lactoferrin transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0008320 protein transmembrane transporter activity Enables the transfer of lactoferrin from one side of a membrane to the other. http://purl.obolibrary.org/obo/CL_1000909 kidney loop of Henle epithelial cell http://purl.obolibrary.org/obo/CL_1000494 nephron tubule epithelial cell Any nephron tubule epithelial cell that is part of some loop of Henle. http://purl.obolibrary.org/obo/CL_1000979 ureter smooth muscle cell http://purl.obolibrary.org/obo/CL_1000601 ureteral cell Any smooth muscle cell that is part of some muscular coat of ureter. http://purl.obolibrary.org/obo/GO_0033571 lactoferrin transport http://purl.obolibrary.org/obo/GO_0015031 protein transport The directed movement of lactoferrin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/CL_1001005 glomerular capillary endothelial cell http://purl.obolibrary.org/obo/CL_1000892 kidney capillary endothelial cell An endothelial cell that is part of the glomerular capillary of the kidney. http://purl.obolibrary.org/obo/GO_0033574 response to testosterone http://purl.obolibrary.org/obo/GO_0033993 response to lipid Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a testosterone stimulus. http://purl.obolibrary.org/obo/CL_1001006 kidney afferent arteriole cell http://purl.obolibrary.org/obo/CL_1000891 kidney arterial blood vessel cell An endothelial cell which is part of the afferent arteriole in the kidney. This cell is responsible for maintaining renal blood flow and glomerular filtration rate. http://purl.obolibrary.org/obo/GO_0033602 negative regulation of dopamine secretion http://purl.obolibrary.org/obo/GO_0033604 negative regulation of catecholamine secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of dopamine. http://purl.obolibrary.org/obo/CL_1001009 kidney efferent arteriole cell http://purl.obolibrary.org/obo/CL_1000891 kidney arterial blood vessel cell Any kidney arterial blood vessel cell that is part of some renal efferent arteriole. http://purl.obolibrary.org/obo/GO_0033603 positive regulation of dopamine secretion http://purl.obolibrary.org/obo/GO_0033605 positive regulation of catecholamine secretion Any process that activates or increases the frequency, rate or extent of the regulated release of dopamine. http://purl.obolibrary.org/obo/CL_1001016 kidney loop of Henle ascending limb epithelial cell http://purl.obolibrary.org/obo/CL_1000909 kidney loop of Henle epithelial cell Any kidney loop of Henle epithelial cell that is part of some ascending limb of loop of Henle. http://purl.obolibrary.org/obo/GO_0033684 regulation of luteinizing hormone secretion http://purl.obolibrary.org/obo/GO_0032276 regulation of gonadotropin secretion Any process that modulates the frequency, rate or extent of the regulated release of luteinizing hormone. http://purl.obolibrary.org/obo/CL_1001021 kidney loop of Henle descending limb epithelial cell http://purl.obolibrary.org/obo/CL_1000909 kidney loop of Henle epithelial cell Any kidney loop of Henle epithelial cell that is part of some descending limb of loop of Henle. http://purl.obolibrary.org/obo/GO_0033685 negative regulation of luteinizing hormone secretion http://purl.obolibrary.org/obo/GO_0033684 regulation of luteinizing hormone secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of luteinizing hormone. http://purl.obolibrary.org/obo/CL_1001033 peritubular capillary endothelial cell http://purl.obolibrary.org/obo/CL_1000892 kidney capillary endothelial cell An endothelial cell that is part of the peritubular capillary of the kidney. This cell is highly fenestrated and plays a vital role in the kidney's filtration process, enabling the exchange of materials between the blood and the renal tubules. http://purl.obolibrary.org/obo/GO_0033686 positive regulation of luteinizing hormone secretion http://purl.obolibrary.org/obo/GO_0033684 regulation of luteinizing hormone secretion Any process that activates or increases the frequency, rate or extent of the regulated release of luteinizing hormone. http://purl.obolibrary.org/obo/CL_1001036 vasa recta cell http://purl.obolibrary.org/obo/CL_2000008 microvascular endothelial cell A cell that is part of a vasa recta. http://purl.obolibrary.org/obo/GO_0033687 osteoblast proliferation http://purl.obolibrary.org/obo/GO_0008283 cell population proliferation The multiplication or reproduction of osteoblasts, resulting in the expansion of an osteoblast cell population. An osteoblast is a bone-forming cell which secretes an extracellular matrix. Hydroxyapatite crystals are then deposited into the matrix to form bone. http://purl.obolibrary.org/obo/CL_1001045 kidney cortex artery cell http://purl.obolibrary.org/obo/CL_1000891 kidney arterial blood vessel cell Any kidney arterial blood vessel cell that is part of some renal cortex artery. http://purl.obolibrary.org/obo/GO_0033688 regulation of osteoblast proliferation http://purl.obolibrary.org/obo/GO_0042127 regulation of cell population proliferation Any process that modulates the frequency, rate or extent of osteoblast proliferation. http://purl.obolibrary.org/obo/CL_1001052 kidney cortex vein cell http://purl.obolibrary.org/obo/CL_1000893 kidney venous blood vessel cell Any kidney venous blood vessel cell that is part of some renal cortex vein. http://purl.obolibrary.org/obo/GO_0033689 negative regulation of osteoblast proliferation http://purl.obolibrary.org/obo/GO_0008285 negative regulation of cell population proliferation Any process that stops, prevents or reduces the rate or extent of osteoblast proliferation. http://purl.obolibrary.org/obo/CL_1001096 kidney afferent arteriole endothelial cell http://purl.obolibrary.org/obo/CL_1001006 kidney afferent arteriole cell An endothelial cell that lines the interior surface of the afferent arteriole and maintains vascular tone. This cell responds to changing ion concentrations and blood pressure by releasing vasoactive substances, in order to regulate blood flow into the glomeruli, which is essential for glomerular filtration. http://purl.obolibrary.org/obo/GO_0033690 positive regulation of osteoblast proliferation http://purl.obolibrary.org/obo/GO_0033688 regulation of osteoblast proliferation Any process that activates or increases the rate or extent of osteoblast proliferation. http://purl.obolibrary.org/obo/CL_1001097 kidney afferent arteriole smooth muscle cell http://purl.obolibrary.org/obo/CL_0008035 microcirculation associated smooth muscle cell A smooth muscle cell found in the wall of the afferent arteriole. This cell contracts and relaxes in response to changes in blood pressure, a process known as a myogenic response, to alter artery diameter and regulate blood flow into the glomeruli. http://purl.obolibrary.org/obo/GO_0033696 heterochromatin boundary formation http://purl.obolibrary.org/obo/GO_0070828 heterochromatin organization A process that forms a boundary that limits the spreading of heterochromatin along a chromosome. http://purl.obolibrary.org/obo/GO_0033750 ribosome localization http://purl.obolibrary.org/obo/GO_0051640 organelle localization A process in which a ribosome is transported to, and/or maintained in, a specific location. http://purl.obolibrary.org/obo/CL_1001099 kidney efferent arteriole endothelial cell http://purl.obolibrary.org/obo/CL_1001009 kidney efferent arteriole cell Any endothelial cell that is part of some renal efferent arteriole. http://purl.obolibrary.org/obo/GO_0033762 response to glucagon http://purl.obolibrary.org/obo/GO_0043434 response to peptide hormone Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucagon stimulus. http://purl.obolibrary.org/obo/CL_1001100 kidney efferent arteriole smooth muscle cell http://purl.obolibrary.org/obo/CL_0008035 microcirculation associated smooth muscle cell Any smooth muscle cell that is part of some renal efferent arteriole. http://purl.obolibrary.org/obo/CL_1001106 kidney loop of Henle thick ascending limb epithelial cell http://purl.obolibrary.org/obo/CL_1001016 kidney loop of Henle ascending limb epithelial cell An epithelial cell that is part of some loop of Henle thick ascending limb. It is known in some mammalian species that this cell may express the Na+-K+-2Cl− cotransporter (NKCC2) apically. http://purl.obolibrary.org/obo/GO_0034067 protein localization to Golgi apparatus http://purl.obolibrary.org/obo/GO_0033365 protein localization to organelle A process in which a protein is transported to, or maintained in, a location within the Golgi apparatus. http://purl.obolibrary.org/obo/GO_0034097 response to cytokine http://purl.obolibrary.org/obo/GO_1901652 response to peptide Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokine stimulus. http://purl.obolibrary.org/obo/CL_1001107 kidney loop of Henle thin ascending limb epithelial cell http://purl.obolibrary.org/obo/CL_1001016 kidney loop of Henle ascending limb epithelial cell An epithelial cell that is part of some loop of Henle thin ascending limb. http://purl.obolibrary.org/obo/CL_1001108 kidney loop of Henle medullary thick ascending limb epithelial cell http://purl.obolibrary.org/obo/CL_1001106 kidney loop of Henle thick ascending limb epithelial cell An epithelial cell that is part of some loop of Henle thick ascending limb segment located in the renal medulla. http://purl.obolibrary.org/obo/GO_0034101 erythrocyte homeostasis http://purl.obolibrary.org/obo/GO_0002262 myeloid cell homeostasis Any process of regulating the production and elimination of erythrocytes within an organism. http://purl.obolibrary.org/obo/GO_0034102 erythrocyte clearance http://purl.obolibrary.org/obo/GO_0048771 tissue remodeling The selective elimination of erythrocytes from the body by autoregulatory mechanisms. http://purl.obolibrary.org/obo/CL_1001109 kidney loop of Henle cortical thick ascending limb epithelial cell http://purl.obolibrary.org/obo/CL_1001106 kidney loop of Henle thick ascending limb epithelial cell An epithelial cell that is part of some loop of Henle thick ascending limb segment located in the renal cortex. http://purl.obolibrary.org/obo/GO_0034103 regulation of tissue remodeling http://purl.obolibrary.org/obo/GO_0051239 regulation of multicellular organismal process Any process that modulates the frequency, rate, or extent of tissue remodeling. http://purl.obolibrary.org/obo/CL_1001111 kidney loop of Henle thin descending limb epithelial cell http://purl.obolibrary.org/obo/CL_1001021 kidney loop of Henle descending limb epithelial cell An epithelial cell that is part of some loop of Henle thin descending limb. http://purl.obolibrary.org/obo/GO_0034104 negative regulation of tissue remodeling http://purl.obolibrary.org/obo/GO_0034103 regulation of tissue remodeling Any process that stops, prevents, or reduces the frequency, rate, or extent of tissue remodeling. http://purl.obolibrary.org/obo/CL_1001123 kidney outer medulla peritubular capillary cell http://purl.obolibrary.org/obo/CL_1001033 peritubular capillary endothelial cell An endothelial cell that is part of the peritubular capillary of the outer renal medulla. http://purl.obolibrary.org/obo/GO_0034105 positive regulation of tissue remodeling http://purl.obolibrary.org/obo/GO_0034103 regulation of tissue remodeling Any process that activates or increases the frequency, rate, or extent of tissue remodeling. http://purl.obolibrary.org/obo/CL_1001124 kidney cortex peritubular capillary cell http://purl.obolibrary.org/obo/CL_1001033 peritubular capillary endothelial cell An endothelial cell that is part of the peritubular capillary of the renal cortex. http://purl.obolibrary.org/obo/CL_1001126 inner renal medulla vasa recta cell http://purl.obolibrary.org/obo/CL_1001036 vasa recta cell Any vasa recta cell that is part of some inner renal medulla vasa recta. http://purl.obolibrary.org/obo/GO_0034106 regulation of erythrocyte clearance http://purl.obolibrary.org/obo/GO_0034103 regulation of tissue remodeling Any process that modulates the frequency, rate, or extent of erythrocyte clearance. http://purl.obolibrary.org/obo/CL_1001127 outer renal medulla vasa recta cell http://purl.obolibrary.org/obo/CL_1001036 vasa recta cell Any vasa recta cell that is part of some outer renal medulla vasa recta. http://purl.obolibrary.org/obo/GO_0034107 negative regulation of erythrocyte clearance http://purl.obolibrary.org/obo/GO_0034106 regulation of erythrocyte clearance Any process that stops, prevents, or reduces the frequency, rate, or extent of erythrocyte clearance. http://purl.obolibrary.org/obo/CL_1001131 vasa recta ascending limb cell http://purl.obolibrary.org/obo/CL_1001036 vasa recta cell A cell that is part of some vasa recta ascending limb. http://purl.obolibrary.org/obo/GO_0034108 positive regulation of erythrocyte clearance http://purl.obolibrary.org/obo/GO_0034106 regulation of erythrocyte clearance Any process that activates or increases the frequency, rate, or extent of erythrocyte clearance. http://purl.obolibrary.org/obo/CL_1001135 arcuate artery cell http://purl.obolibrary.org/obo/CL_1001045 kidney cortex artery cell Any kidney cortex artery cell that is part of some kidney arcuate artery. http://purl.obolibrary.org/obo/GO_0034242 negative regulation of syncytium formation by plasma membrane fusion http://purl.obolibrary.org/obo/GO_0051129 negative regulation of cellular component organization Any process that decreases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells. http://purl.obolibrary.org/obo/CL_1001138 interlobular artery cell http://purl.obolibrary.org/obo/CL_1001045 kidney cortex artery cell Any kidney cortex artery cell that is part of some interlobular artery. http://purl.obolibrary.org/obo/GO_0034307 regulation of ascospore formation http://purl.obolibrary.org/obo/GO_0060284 regulation of cell development Any process that modulates the frequency, rate or extent of ascospore formation. An example of this process is found in Saccharomyces cerevisiae. http://purl.obolibrary.org/obo/GO_0034487 vacuolar amino acid transmembrane transport http://purl.obolibrary.org/obo/GO_0003333 amino acid transmembrane transport The process in which an amino acid is transported from one side of the vacuolar membrane to the other. http://purl.obolibrary.org/obo/CL_1001142 arcuate vein cell http://purl.obolibrary.org/obo/CL_1001052 kidney cortex vein cell Any kidney cortex vein cell that is part of some kidney arcuate vein. http://purl.obolibrary.org/obo/CL_1001145 interlobular vein cell http://purl.obolibrary.org/obo/CL_1001052 kidney cortex vein cell Any kidney cortex vein cell that is part of some renal interlobular vein. http://purl.obolibrary.org/obo/GO_0034762 regulation of transmembrane transport http://purl.obolibrary.org/obo/GO_0051049 regulation of transport Any process that modulates the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other. http://purl.obolibrary.org/obo/CL_1001209 inner medulla vasa recta ascending limb cell http://purl.obolibrary.org/obo/CL_1001131 vasa recta ascending limb cell Any vasa recta ascending limb cell that is part of some inner medulla ascending vasa recta. http://purl.obolibrary.org/obo/GO_0034766 negative regulation of monoatomic ion transmembrane transport http://purl.obolibrary.org/obo/GO_0043271 negative regulation of monoatomic ion transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other. http://purl.obolibrary.org/obo/CL_1001210 outer medulla vasa recta ascending limb cell http://purl.obolibrary.org/obo/CL_1001131 vasa recta ascending limb cell Any vasa recta ascending limb cell that is part of some outer medulla ascending vasa recta. http://purl.obolibrary.org/obo/CL_1001213 arcuate artery endothelial cell http://purl.obolibrary.org/obo/CL_1001135 arcuate artery cell Any endothelial cell that is part of some kidney arcuate artery. http://purl.obolibrary.org/obo/GO_0034767 positive regulation of monoatomic ion transmembrane transport http://purl.obolibrary.org/obo/GO_0043270 positive regulation of monoatomic ion transport Any process that activates or increases the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other. http://purl.obolibrary.org/obo/CL_1001214 arcuate artery smooth muscle cell http://purl.obolibrary.org/obo/CL_1001135 arcuate artery cell Any smooth muscle cell that is part of some kidney arcuate artery. http://purl.obolibrary.org/obo/GO_0035107 appendage morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structures of appendages are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch. http://purl.obolibrary.org/obo/CL_1001216 interlobulary artery endothelial cell http://purl.obolibrary.org/obo/CL_1001138 interlobular artery cell Any endothelial cell that is part of some interlobular artery. http://purl.obolibrary.org/obo/GO_0035108 limb morphogenesis http://purl.obolibrary.org/obo/GO_0035107 appendage morphogenesis The process in which the anatomical structures of a limb are generated and organized. A limb is a paired appendage of a tetrapod used for locomotion or grasping. http://purl.obolibrary.org/obo/CL_1001217 interlobulary artery smooth muscle cell http://purl.obolibrary.org/obo/CL_1001138 interlobular artery cell Any smooth muscle cell that is part of some interlobular artery. http://purl.obolibrary.org/obo/GO_0035112 genitalia morphogenesis http://purl.obolibrary.org/obo/GO_0009887 animal organ morphogenesis The process in which the anatomical structures of genitalia are generated and organized. The genitalia are the organs of reproduction or generation, external and internal. http://purl.obolibrary.org/obo/CL_1001220 arcuate vein endothelial cell http://purl.obolibrary.org/obo/CL_1001142 arcuate vein cell Any endothelial cell that is part of some kidney arcuate vein. http://purl.obolibrary.org/obo/CL_1001221 arcuate vein smooth muscle cell http://purl.obolibrary.org/obo/CL_1001142 arcuate vein cell Any smooth muscle cell that is part of some kidney arcuate vein. http://purl.obolibrary.org/obo/GO_0035270 endocrine system development http://purl.obolibrary.org/obo/GO_0048731 system development Progression of the endocrine system over time, from its formation to a mature structure. The endocrine system is a system of hormones and ductless glands, where the glands release hormones directly into the blood, lymph or other intercellular fluid, and the hormones circulate within the body to affect distant organs. The major glands that make up the human endocrine system are the hypothalamus, pituitary, thyroid, parathryoids, adrenals, pineal body, and the reproductive glands which include the ovaries and testes. http://purl.obolibrary.org/obo/CL_1001223 interlobulary vein endothelial cell http://purl.obolibrary.org/obo/CL_1001145 interlobular vein cell Any endothelial cell that is part of some renal interlobular vein. http://purl.obolibrary.org/obo/GO_0035869 ciliary transition zone http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure A region of the cilium between the basal body and proximal segment that is characterized by Y-shaped assemblages that connect axonemal microtubules to the ciliary membrane. The ciliary transition zone appears to function as a gate that controls ciliary membrane composition and separates the cytosol from the ciliary plasm. http://purl.obolibrary.org/obo/CL_1001224 interlobulary vein smooth muscle cell http://purl.obolibrary.org/obo/CL_1001145 interlobular vein cell Any smooth muscle cell that is part of some renal interlobular vein. http://purl.obolibrary.org/obo/CL_1001225 kidney collecting duct cell http://purl.obolibrary.org/obo/CL_1000497 kidney cell A cell that is part of a collecting duct of renal tubule. http://purl.obolibrary.org/obo/GO_0036344 platelet morphogenesis http://purl.obolibrary.org/obo/GO_0000902 cell morphogenesis Generation and organization of a platelet, a non-nucleated disk-shaped cell formed by extrusion from megakaryocytes, found in the blood of all mammals, and mainly involved in blood coagulation. http://purl.obolibrary.org/obo/CL_1001285 vasa recta descending limb cell http://purl.obolibrary.org/obo/CL_1001036 vasa recta cell A cell that is part of some vasa recta descending limb. http://purl.obolibrary.org/obo/CL_1001286 inner medulla vasa recta descending limb cell http://purl.obolibrary.org/obo/CL_1001285 vasa recta descending limb cell Any vasa recta descending limb cell that is part of some inner medulla descending vasa recta. http://purl.obolibrary.org/obo/GO_0036477 somatodendritic compartment http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure The region of a neuron that includes the cell body (cell soma) and dendrite(s), but excludes the axon. http://purl.obolibrary.org/obo/CL_1001287 outer medulla vasa recta descending limb cell http://purl.obolibrary.org/obo/CL_1001285 vasa recta descending limb cell Any vasa recta descending limb cell that is part of some outer medulla descending vasa recta. http://purl.obolibrary.org/obo/CL_1001318 renal interstitial pericyte http://purl.obolibrary.org/obo/CL_1000500 kidney interstitial cell A pericyte cell located in the kidney interstitium. http://purl.obolibrary.org/obo/GO_0040011 locomotion http://purl.obolibrary.org/obo/GO_0008150 biological_process Self-propelled movement of a cell or organism from one location to another. http://purl.obolibrary.org/obo/CL_1001319 bladder cell http://purl.obolibrary.org/obo/CL_1000600 lower urinary tract cell Any cell that is part of some urinary bladder. http://purl.obolibrary.org/obo/GO_0040020 regulation of meiotic nuclear division http://purl.obolibrary.org/obo/GO_0051445 regulation of meiotic cell cycle Any process that modulates the frequency, rate or extent of meiotic nuclear division, the process in which the nucleus of a diploid cell divides twice forming four haploid cells, one or more of which usually function as gametes. http://purl.obolibrary.org/obo/CL_1001320 urethra cell http://purl.obolibrary.org/obo/CL_1000600 lower urinary tract cell Any cell that is part of some urethra. http://purl.obolibrary.org/obo/GO_0042102 positive regulation of T cell proliferation http://purl.obolibrary.org/obo/GO_0050870 positive regulation of T cell activation Any process that activates or increases the rate or extent of T cell proliferation. http://purl.obolibrary.org/obo/CL_1001428 bladder urothelial cell http://purl.obolibrary.org/obo/CL_1001319 bladder cell A urothelial cell that is part of the urothelium of the urinary bladder. http://purl.obolibrary.org/obo/GO_0042129 regulation of T cell proliferation http://purl.obolibrary.org/obo/GO_0050863 regulation of T cell activation Any process that modulates the frequency, rate or extent of T cell proliferation. http://purl.obolibrary.org/obo/CL_1001430 urethra urothelial cell http://purl.obolibrary.org/obo/CL_1000296 epithelial cell of urethra A urothelial cell that is part of the urethra urothelium. This cell plays a crucial role in maintaining the urethral barrier function, protecting against toxic substances in urine, sensing environmental changes, and defending against pathogen entry. http://purl.obolibrary.org/obo/GO_0042130 negative regulation of T cell proliferation http://purl.obolibrary.org/obo/GO_0050868 negative regulation of T cell activation Any process that stops, prevents or reduces the rate or extent of T cell proliferation. http://purl.obolibrary.org/obo/CL_1001431 kidney collecting duct principal cell http://purl.obolibrary.org/obo/CL_1000454 kidney collecting duct epithelial cell Any renal principal cell that is part of some collecting duct of renal tubule. http://purl.obolibrary.org/obo/GO_0042246 tissue regeneration http://purl.obolibrary.org/obo/GO_0031099 regeneration The regrowth of lost or destroyed tissues. http://purl.obolibrary.org/obo/CL_1001432 kidney collecting duct intercalated cell http://purl.obolibrary.org/obo/CL_1000454 kidney collecting duct epithelial cell Any renal intercalated cell that is part of some collecting duct of renal tubule. http://purl.obolibrary.org/obo/GO_0042287 MHC protein binding http://purl.obolibrary.org/obo/GO_0005102 signaling receptor binding Binding to a major histocompatibility complex molecule; a set of molecules displayed on cell surfaces that are responsible for lymphocyte recognition and antigen presentation. http://purl.obolibrary.org/obo/CL_1001433 epithelial cell of exocrine pancreas http://purl.obolibrary.org/obo/CL_0000083 epithelial cell of pancreas An epithelial cell of the exocrine pancreas. http://purl.obolibrary.org/obo/GO_0042306 regulation of protein import into nucleus http://purl.obolibrary.org/obo/GO_1900180 regulation of protein localization to nucleus Any process that modulates the frequency, rate or extent of movement of proteins from the cytoplasm to the nucleus. http://purl.obolibrary.org/obo/CL_1001434 olfactory bulb interneuron http://purl.obolibrary.org/obo/CL_0000101 sensory neuron A neuron residing in the olfactory bulb that serve to process and refine signals arising from olfactory sensory neurons http://purl.obolibrary.org/obo/GO_0042307 positive regulation of protein import into nucleus http://purl.obolibrary.org/obo/GO_1900182 positive regulation of protein localization to nucleus Any process that activates or increases the frequency, rate or extent of movement of proteins from the cytoplasm into the nucleus. http://purl.obolibrary.org/obo/CL_1001435 periglomerular cell http://purl.obolibrary.org/obo/CL_1001434 olfactory bulb interneuron The small neuron in the glomerular layer of the olfactory bulb whose dendrites arborize within a glomerulus, where it receives synaptic input from olfactory receptor cell axon terminals, and also engages in dendrodendritic interactions with mitral and tufted cell dendrites; uses both GABA and dopamine as a neurotransmitter. http://purl.obolibrary.org/obo/GO_0042308 negative regulation of protein import into nucleus http://purl.obolibrary.org/obo/GO_1900181 negative regulation of protein localization to nucleus Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of proteins from the cytoplasm into the nucleus. http://purl.obolibrary.org/obo/GO_0042470 melanosome http://purl.obolibrary.org/obo/GO_0048770 pigment granule A tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored. Melanosomes are synthesized in melanocyte cells. http://purl.obolibrary.org/obo/CL_1001436 hair-tylotrich neuron http://purl.obolibrary.org/obo/CL_0002487 cutaneous/subcutaneous mechanoreceptor cell The subcutaneous mechanoreceptors that innervate tylotrich hair follicles. http://purl.obolibrary.org/obo/GO_0042552 myelination http://purl.obolibrary.org/obo/GO_0008366 axon ensheathment The process in which myelin sheaths are formed and maintained around neurons. Oligodendrocytes in the brain and spinal cord and Schwann cells in the peripheral nervous system wrap axons with compact layers of their plasma membrane. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier. http://purl.obolibrary.org/obo/CL_1001437 hair-down neuron http://purl.obolibrary.org/obo/CL_0002487 cutaneous/subcutaneous mechanoreceptor cell The subcutaneous mechanoreceptors that innervate vellus hairs. http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion http://purl.obolibrary.org/obo/CL_3000004 peripheral sensory neuron A sensory neuron of the dorsal root ganglia that senses body position and sends information about how much the muscle is stretched to the spinal cord. http://purl.obolibrary.org/obo/GO_0042554 superoxide anion generation http://purl.obolibrary.org/obo/GO_0006801 superoxide metabolic process The enzymatic generation of superoxide, the superoxide anion O2- (superoxide free radical), or any compound containing this species, by a cell in response to environmental stress, thereby mediating the activation of various stress-inducible signaling pathways. http://purl.obolibrary.org/obo/CL_1001474 medium spiny neuron http://purl.obolibrary.org/obo/CL_0000617 GABAergic neuron An inhibitory, GABAergic projection neuron in the striatum that integrates glutamatergic signals arising from the cerebral cortex and thalamus. http://purl.obolibrary.org/obo/GO_0042611 MHC protein complex http://purl.obolibrary.org/obo/GO_0098797 plasma membrane protein complex A transmembrane protein complex composed of an MHC alpha chain and, in most cases, either an MHC class II beta chain or an invariant beta2-microglobin chain, and with or without a bound peptide, lipid, or polysaccharide antigen. http://purl.obolibrary.org/obo/CL_1001502 mitral cell http://purl.obolibrary.org/obo/CL_1001434 olfactory bulb interneuron The large glutaminergic nerve cells whose dendrites synapse with axons of the olfactory receptor neurons in the glomerular layer of the olfactory bulb, and whose axons pass centrally in the olfactory tract to the olfactory cortex. http://purl.obolibrary.org/obo/GO_0042633 hair cycle http://purl.obolibrary.org/obo/GO_0042303 molting cycle The cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair; one of the collection or mass of filaments growing from the skin of an animal, and forming a covering for a part of the head or for any part or the whole of the body. http://purl.obolibrary.org/obo/CL_1001503 olfactory bulb tufted cell http://purl.obolibrary.org/obo/CL_2000029 central nervous system neuron The principal glutaminergic neuron located in the outer third of the external plexiform layer of the olfactory bulb; a single short primary dendrite traverses the outer external plexiform layer and terminates within an olfactory glomerulus in a tuft of branches, where it receives the input from olfactory receptor neuron axon terminals; axons of the tufted cells transfer information to a number of areas in the brain, including the piriform cortex, entorhinal cortex, olfactory tubercle, and amygdala. http://purl.obolibrary.org/obo/GO_0042698 ovulation cycle http://purl.obolibrary.org/obo/GO_0048609 multicellular organismal reproductive process The type of sexual cycle seen in females, often with physiologic changes in the endometrium that recur at regular intervals during the reproductive years. http://purl.obolibrary.org/obo/GO_0043022 ribosome binding http://purl.obolibrary.org/obo/GO_0043021 ribonucleoprotein complex binding Binding to a ribosome. http://purl.obolibrary.org/obo/CL_1001505 parvocellular neurosecretory cell http://purl.obolibrary.org/obo/CL_2000030 hypothalamus cell The secretory neurons of the paraventricular nucleus that synthesize and secrete vasopressin, corticotropin-releasing factor (CRF) and thyrotropin-releasing hormone (TRH) into blood vessels in the hypothalamo-pituitary portal system. http://purl.obolibrary.org/obo/GO_0043025 neuronal cell body http://purl.obolibrary.org/obo/GO_0044297 cell body The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites. http://purl.obolibrary.org/obo/GO_0043062 extracellular structure organization http://purl.obolibrary.org/obo/GO_0016043 cellular component organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures in the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane, and also covers the host cell environment outside an intracellular parasite. http://purl.obolibrary.org/obo/CL_1001509 glycinergic neuron http://purl.obolibrary.org/obo/CL_0000540 neuron The neurons that utilize glycine as a neurotransmitter. http://purl.obolibrary.org/obo/CL_1001516 intestinal enteroendocrine cell http://purl.obolibrary.org/obo/CL_0002563 intestinal epithelial cell The various hormone- or neurotransmitter-secreting cells present throughout the mucosa of the intestinal tract. http://purl.obolibrary.org/obo/GO_0043069 negative regulation of programmed cell death http://purl.obolibrary.org/obo/GO_0043067 regulation of programmed cell death Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes. http://purl.obolibrary.org/obo/CL_1001517 stomach enteroendocrine cell http://purl.obolibrary.org/obo/CL_0002178 epithelial cell of stomach The various hormone- or neurotransmitter-secreting cells present throughout the mucosa of the stomach. http://purl.obolibrary.org/obo/CL_1001561 vomeronasal sensory neuron http://purl.obolibrary.org/obo/CL_0000101 sensory neuron Chemosensitive cells that innervate the vomernasal organ epithelium and are responsible for receiving and transmitting pheromone signals. http://purl.obolibrary.org/obo/GO_0043177 organic acid binding http://purl.obolibrary.org/obo/GO_0036094 small molecule binding Binding to an organic acid, any acidic compound containing carbon in covalent linkage. http://purl.obolibrary.org/obo/CL_1001567 lung endothelial cell http://purl.obolibrary.org/obo/CL_0002139 endothelial cell of vascular tree Any endothelial cell of vascular tree that is part of some lung. http://purl.obolibrary.org/obo/GO_0043227 membrane-bounded organelle http://purl.obolibrary.org/obo/GO_0043226 organelle Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane. http://purl.obolibrary.org/obo/CL_1001568 pulmonary artery endothelial cell http://purl.obolibrary.org/obo/CL_1000413 endothelial cell of artery Any endothelial cell of vascular tree that is part of some pulmonary artery. http://purl.obolibrary.org/obo/GO_0043233 organelle lumen http://purl.obolibrary.org/obo/GO_0031974 membrane-enclosed lumen The internal volume enclosed by the membranes of a particular organelle; includes the volume enclosed by a single organelle membrane, e.g. endoplasmic reticulum lumen, or the volume enclosed by the innermost of the two lipid bilayers of an organelle envelope, e.g. nuclear lumen. http://purl.obolibrary.org/obo/CL_1001569 hippocampal interneuron http://purl.obolibrary.org/obo/CL_0002608 hippocampal neuron An interneuron with a soma found in the hippocampus. http://purl.obolibrary.org/obo/GO_0043253 chloroplast ribosome http://purl.obolibrary.org/obo/GO_0009547 plastid ribosome A ribosome contained within a chloroplast. http://purl.obolibrary.org/obo/CL_1001571 hippocampal pyramidal neuron http://purl.obolibrary.org/obo/CL_4023111 cerebral cortex pyramidal neuron A pyramidal neuron with a soma found in the hippocampus. http://purl.obolibrary.org/obo/GO_0043297 apical junction assembly http://purl.obolibrary.org/obo/GO_0007043 cell-cell junction assembly The formation of an apical junction, a functional unit located near the cell apex at the points of contact between epithelial cells composed of the tight junction, the zonula adherens junction and the desmosomes, by the aggregation, arrangement and bonding together of its constituents. http://purl.obolibrary.org/obo/CL_1001572 colon endothelial cell http://purl.obolibrary.org/obo/CL_0000131 gut endothelial cell A vascular endothelial cell found in colon blood vessels. http://purl.obolibrary.org/obo/GO_0043370 regulation of CD4-positive, alpha-beta T cell differentiation http://purl.obolibrary.org/obo/GO_2000514 regulation of CD4-positive, alpha-beta T cell activation Any process that modulates the frequency, rate, or extent of CD4-positive, alpha-beta T cell differentiation. http://purl.obolibrary.org/obo/CL_1001573 nasopharyngeal epithelial cell http://purl.obolibrary.org/obo/CL_0002631 epithelial cell of upper respiratory tract Cell of the nasopharyngeal epithelium. http://purl.obolibrary.org/obo/GO_0043371 negative regulation of CD4-positive, alpha-beta T cell differentiation http://purl.obolibrary.org/obo/GO_2000515 negative regulation of CD4-positive, alpha-beta T cell activation Any process that stops, prevents, or reduces the frequency, rate, or extent of CD4-positive, alpha-beta T cell differentiation. http://purl.obolibrary.org/obo/CL_1001575 uterine cervix squamous cell http://purl.obolibrary.org/obo/CL_0002535 epithelial cell of cervix Squamous cell of uterine cervix epithelium. http://purl.obolibrary.org/obo/GO_0043372 positive regulation of CD4-positive, alpha-beta T cell differentiation http://purl.obolibrary.org/obo/GO_2000516 positive regulation of CD4-positive, alpha-beta T cell activation Any process that activates or increases the frequency, rate or extent of CD4-positive, alpha-beta T cell differentiation. http://purl.obolibrary.org/obo/GO_0043393 regulation of protein binding http://purl.obolibrary.org/obo/GO_0051098 regulation of binding Any process that modulates the frequency, rate or extent of protein binding. http://purl.obolibrary.org/obo/CL_1001576 oral mucosa squamous cell http://purl.obolibrary.org/obo/CL_0002251 epithelial cell of alimentary canal Squamous cell of oral epithelium. http://purl.obolibrary.org/obo/GO_0043434 response to peptide hormone http://purl.obolibrary.org/obo/GO_1901698 response to nitrogen compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide hormone stimulus. A peptide hormone is any of a class of peptides that are secreted into the blood stream and have endocrine functions in living animals. http://purl.obolibrary.org/obo/CL_1001577 tonsil squamous cell http://purl.obolibrary.org/obo/CL_0002251 epithelial cell of alimentary canal Squamous cell of tonsil epithelium. http://purl.obolibrary.org/obo/GO_0043473 pigmentation http://purl.obolibrary.org/obo/GO_0008150 biological_process The accumulation of pigment in an organism, tissue or cell, either by increased deposition or by increased number of cells. http://purl.obolibrary.org/obo/CL_1001578 vagina squamous cell http://purl.obolibrary.org/obo/CL_0000240 stratified squamous epithelial cell Squamous cell of vaginal epithelium. http://purl.obolibrary.org/obo/GO_0043555 regulation of translation in response to stress http://purl.obolibrary.org/obo/GO_0006417 regulation of translation Modulation of the frequency, rate or extent of translation as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). http://purl.obolibrary.org/obo/CL_1001579 cerebral cortex glial cell http://purl.obolibrary.org/obo/CL_0000125 glial cell Glial cell of cerebral cortex. http://purl.obolibrary.org/obo/GO_0043556 regulation of translation in response to oxidative stress http://purl.obolibrary.org/obo/GO_0032055 negative regulation of translation in response to stress Any process that modulates the frequency, rate or extent of translation as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals. http://purl.obolibrary.org/obo/CL_1001580 hippocampal glial cell http://purl.obolibrary.org/obo/CL_1001579 cerebral cortex glial cell A glial cell that is part of the hippocampus. http://purl.obolibrary.org/obo/GO_0043584 nose development http://purl.obolibrary.org/obo/GO_0007423 sensory organ development The process whose specific outcome is the progression of the nose over time, from its formation to the mature structure. The nose is the specialized structure of the face that serves as the organ of the sense of smell and as part of the respiratory system. Includes the nasi externus (external nose) and cavitas nasi (nasal cavity). http://purl.obolibrary.org/obo/CL_1001581 lateral ventricle glial cell http://purl.obolibrary.org/obo/CL_0000125 glial cell Glial cell of lateral ventricle. http://purl.obolibrary.org/obo/GO_0043588 skin development http://purl.obolibrary.org/obo/GO_0048513 animal organ development The process whose specific outcome is the progression of the skin over time, from its formation to the mature structure. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner vascular dermis (cutis, corium or true skin) composed mostly of connective tissue. http://purl.obolibrary.org/obo/CL_1001582 lateral ventricle neuron http://purl.obolibrary.org/obo/CL_0012001 neuron of the forebrain Neuron of lateral ventricle. http://purl.obolibrary.org/obo/GO_0043615 astrocyte cell migration http://purl.obolibrary.org/obo/GO_0008347 glial cell migration The orderly movement of an astrocyte, a class of large neuroglial (macroglial) cells in the central nervous system, the largest and most numerous neuroglial cells in the brain and spinal cord. http://purl.obolibrary.org/obo/CL_1001585 appendix glandular cell http://purl.obolibrary.org/obo/CL_1000405 epithelial cell of appendix Glandular cell of appendix epithelium. Example: Goblet cells; enterocytes or absorptive cells; enteroendocrine and M cells. http://purl.obolibrary.org/obo/GO_0043934 sporulation http://purl.obolibrary.org/obo/GO_0032502 developmental process The process whose specific outcome is the progression of a spore over time, from its initiation to the mature structure. A spore is a structure that can be used for dissemination, for survival of adverse conditions because of its heat and desiccation resistance, and/or for reproduction. http://purl.obolibrary.org/obo/CL_1001586 mammary gland glandular cell http://purl.obolibrary.org/obo/CL_0002327 mammary gland epithelial cell Glandular cell of mammary epithelium. Example: glandular cells of large and intermediate ducts, glandular cells in terminal ducts. http://purl.obolibrary.org/obo/GO_0043935 sexual sporulation resulting in formation of a cellular spore http://purl.obolibrary.org/obo/GO_0034293 sexual sporulation The formation of spores derived from the products of meiosis. A cellular spore is a cell form that can be used for dissemination, for survival of adverse conditions because of its heat and desiccation resistance, and/or for reproduction. http://purl.obolibrary.org/obo/CL_1001587 uterine cervix secretory cell http://purl.obolibrary.org/obo/CL_1001591 oviduct secretory cell Glandular cell of uterine cervix epithelium. http://purl.obolibrary.org/obo/GO_0044057 regulation of system process http://purl.obolibrary.org/obo/GO_0051239 regulation of multicellular organismal process Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by any of the organs or tissues in an organ system. http://purl.obolibrary.org/obo/GO_0044088 regulation of vacuole organization http://purl.obolibrary.org/obo/GO_0033043 regulation of organelle organization Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a vacuole. http://purl.obolibrary.org/obo/CL_1001588 colon glandular cell http://purl.obolibrary.org/obo/CL_0011108 colon epithelial cell Glandular cell of colon epithelium. Example: Goblet cells; enterocytes or absorptive cells; enteroendocrine and M cells. http://purl.obolibrary.org/obo/GO_0044092 negative regulation of molecular function http://purl.obolibrary.org/obo/GO_0065009 regulation of molecular function Any process that stops or reduces the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding. http://purl.obolibrary.org/obo/CL_1001589 duodenum secretory cell http://purl.obolibrary.org/obo/CL_1001598 small intestine secretory cell Glandular cell of duodenal epithelium. Example: Enterocytes, Goblet cells, enteroendocrine cells; Paneth cells; M cells; Brunner's gland cell. http://purl.obolibrary.org/obo/GO_0044093 positive regulation of molecular function http://purl.obolibrary.org/obo/GO_0065009 regulation of molecular function Any process that activates or increases the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding. http://purl.obolibrary.org/obo/CL_1001590 epididymis secretory cell http://purl.obolibrary.org/obo/CL_0000068 duct epithelial cell Glandular cell of epididymal epithelium. http://purl.obolibrary.org/obo/GO_0044423 virion component http://purl.obolibrary.org/obo/GO_0005575 cellular_component Any constituent part of a virion, a complete fully infectious extracellular virus particle. http://purl.obolibrary.org/obo/CL_1001591 oviduct secretory cell http://purl.obolibrary.org/obo/CL_1100001 secretory epithelial cell Glandular cell of oviduct epithelium. Example: peg cells, ciliated cells. http://purl.obolibrary.org/obo/GO_0044782 cilium organization http://purl.obolibrary.org/obo/GO_0006996 organelle organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole. http://purl.obolibrary.org/obo/CL_1001592 gallbladder glandular cell http://purl.obolibrary.org/obo/CL_1000415 epithelial cell of gallbladder Glandular cell of gallbladder epithelium. http://purl.obolibrary.org/obo/GO_0044877 protein-containing complex binding http://purl.obolibrary.org/obo/GO_0005488 binding Binding to a macromolecular complex. http://purl.obolibrary.org/obo/CL_1001593 parathyroid glandular cell http://purl.obolibrary.org/obo/CL_0002260 epithelial cell of parathyroid gland Glandular (secretory) cell of parathyroid epithelium. http://purl.obolibrary.org/obo/GO_0045009 chitosome http://purl.obolibrary.org/obo/GO_0031410 cytoplasmic vesicle An intracellular membrane-bounded particle found in fungi and containing chitin synthase; it synthesizes chitin microfibrils. Chitin synthase activity exists in chitosomes and they are proposed to act as a reservoir for regulated transport of chitin synthase enzymes to the division septum. http://purl.obolibrary.org/obo/CL_1001595 rectum glandular cell http://purl.obolibrary.org/obo/CL_0002658 glandular cell of the large intestine Glandular cell of rectal epithelium. Example: Goblet cell; enterocytes or absorptive cells; enteroendocrine and M cells. http://purl.obolibrary.org/obo/GO_0045110 intermediate filament bundle assembly http://purl.obolibrary.org/obo/GO_0045109 intermediate filament organization The formation of the bundles of intermediate filaments. Intermediate filament-associated proteins (IFAPs) cross-link intermediate filaments with one another, forming a bundle or a network, and with other cell structures, including the plasma membrane. The organization of intermediate filaments and their supportive function in various cells types depends in large part on their linkage to other cell structures via IFAPs. http://purl.obolibrary.org/obo/CL_1001596 salivary gland glandular cell http://purl.obolibrary.org/obo/CL_0009005 salivary gland cell Glandular cell of salivary gland. Example: Serous cells, mucous cells, cuboidal epithelial cells of the intercalated ducts, simple cuboidal epithelium of the striated ducts, epithelial cells of excretory ducts. http://purl.obolibrary.org/obo/GO_0045168 cell-cell signaling involved in cell fate commitment http://purl.obolibrary.org/obo/GO_0007267 cell-cell signaling Signaling at long or short range between cells that results in the commitment of a cell to a certain fate. http://purl.obolibrary.org/obo/CL_1001597 seminal vesicle glandular cell http://purl.obolibrary.org/obo/CL_0000150 glandular secretory epithelial cell Glandular cell of seminal vesicle epithelium. http://purl.obolibrary.org/obo/GO_0045185 maintenance of protein location http://purl.obolibrary.org/obo/GO_0051235 maintenance of location Any process in which a protein is maintained in a location and prevented from moving elsewhere. These include sequestration, stabilization to prevent transport elsewhere and the active retrieval of proteins that do move away. http://purl.obolibrary.org/obo/CL_1001598 small intestine secretory cell http://purl.obolibrary.org/obo/CL_0002254 epithelial cell of small intestine A glandular cell found in the epithelium of the small intestine. Example: Enterocytes, Goblet cells, enteroendocrine cells; Paneth cells; M cells; Somatostatin-secreting Cells (D-cells) . http://purl.obolibrary.org/obo/GO_0045202 synapse http://purl.obolibrary.org/obo/GO_0030054 cell junction The junction between an axon of one neuron and a dendrite of another neuron, a muscle fiber or a glial cell. As the axon approaches the synapse it enlarges into a specialized structure, the presynaptic terminal bouton, which contains mitochondria and synaptic vesicles. At the tip of the terminal bouton is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic terminal bouton secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane. http://purl.obolibrary.org/obo/CL_1001599 pancreas exocrine glandular cell http://purl.obolibrary.org/obo/CL_1001433 epithelial cell of exocrine pancreas Glandular cell of exocrine pancreas epithelium. Example: pancreatic acinar cell, glandular cells in pancreatic canaliculi, glandular cells in pancreatic ducts. http://purl.obolibrary.org/obo/GO_0045580 regulation of T cell differentiation http://purl.obolibrary.org/obo/GO_0050863 regulation of T cell activation Any process that modulates the frequency, rate or extent of T cell differentiation. http://purl.obolibrary.org/obo/CL_1001601 adrenal gland glandular cell http://purl.obolibrary.org/obo/CL_0000150 glandular secretory epithelial cell Hormone secreting cell located in the cortex of adrenal gland. Glandular cells in the adrenal cortex secrete mineralocorticoids, glucocorticoids and androgens. http://purl.obolibrary.org/obo/GO_0045581 negative regulation of T cell differentiation http://purl.obolibrary.org/obo/GO_0050868 negative regulation of T cell activation Any process that stops, prevents, or reduces the frequency, rate or extent of T cell differentiation. http://purl.obolibrary.org/obo/CL_1001602 cerebral cortex endothelial cell http://purl.obolibrary.org/obo/CL_0002319 neural cell A distinct endothelial cell forming the walls of the capillaries within the cerebral cortex. http://purl.obolibrary.org/obo/GO_0045582 positive regulation of T cell differentiation http://purl.obolibrary.org/obo/GO_0050870 positive regulation of T cell activation Any process that activates or increases the frequency, rate or extent of T cell differentiation. http://purl.obolibrary.org/obo/CL_1001603 lung macrophage http://purl.obolibrary.org/obo/CL_0000235 macrophage Circulating macrophages and tissue macrophages (alveolar macrophages) of lung. http://purl.obolibrary.org/obo/GO_0045589 regulation of regulatory T cell differentiation http://purl.obolibrary.org/obo/GO_0045580 regulation of T cell differentiation Any process that modulates the frequency, rate or extent of differentiation of regulatory T cells. http://purl.obolibrary.org/obo/CL_1001606 foreskin keratinocyte http://purl.obolibrary.org/obo/CL_0000312 keratinocyte Keratinocyte from foreskin. http://purl.obolibrary.org/obo/GO_0045590 negative regulation of regulatory T cell differentiation http://purl.obolibrary.org/obo/GO_0045589 regulation of regulatory T cell differentiation Any process that stops, prevents, or reduces the rate of differentiation of regulatory T cells. http://purl.obolibrary.org/obo/CL_1001607 articular chondrocyte http://purl.obolibrary.org/obo/CL_0000138 chondrocyte Chondrocyte forming the hyaline cartilage found in joints. http://purl.obolibrary.org/obo/GO_0045591 positive regulation of regulatory T cell differentiation http://purl.obolibrary.org/obo/GO_0045589 regulation of regulatory T cell differentiation Any process that activates or increases the frequency, rate or extent of differentiation of regulatory T cells. http://purl.obolibrary.org/obo/CL_1001608 foreskin fibroblast http://purl.obolibrary.org/obo/CL_0002620 skin fibroblast Fibroblast from foreskin. http://purl.obolibrary.org/obo/GO_0045619 regulation of lymphocyte differentiation http://purl.obolibrary.org/obo/GO_0051249 regulation of lymphocyte activation Any process that modulates the frequency, rate or extent of lymphocyte differentiation. http://purl.obolibrary.org/obo/CL_1001609 muscle fibroblast http://purl.obolibrary.org/obo/CL_0000057 fibroblast Fibroblast from muscle organ. http://purl.obolibrary.org/obo/GO_0045620 negative regulation of lymphocyte differentiation http://purl.obolibrary.org/obo/GO_0051250 negative regulation of lymphocyte activation Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte differentiation. http://purl.obolibrary.org/obo/CL_1001610 bone marrow hematopoietic cell http://purl.obolibrary.org/obo/CL_0002092 bone marrow cell Hematopoietic cells resident in the bone marrow. Include: hematopoietic stem cells (lymphoid stem cells and myeloid stem cells) and the precursor cells for thrombocytes, erythrocytes, basophils, neutrophils, eosinophils, monocytes and lymphocytes. http://purl.obolibrary.org/obo/GO_0045621 positive regulation of lymphocyte differentiation http://purl.obolibrary.org/obo/GO_0051251 positive regulation of lymphocyte activation Any process that activates or increases the frequency, rate or extent of lymphocyte differentiation. http://purl.obolibrary.org/obo/CL_1001611 cerebellar neuron http://purl.obolibrary.org/obo/CL_2000029 central nervous system neuron Neuron of the cerebellum. http://purl.obolibrary.org/obo/GO_0045717 negative regulation of fatty acid biosynthetic process http://purl.obolibrary.org/obo/GO_0051055 negative regulation of lipid biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids. http://purl.obolibrary.org/obo/CL_2000000 epidermal melanocyte http://purl.obolibrary.org/obo/CL_1000458 melanocyte of skin Any melanocyte that is part of a epidermis. http://purl.obolibrary.org/obo/GO_0045763 negative regulation of amino acid metabolic process http://purl.obolibrary.org/obo/GO_0009892 negative regulation of metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amino acid. http://purl.obolibrary.org/obo/CL_2000001 peripheral blood mononuclear cell http://purl.obolibrary.org/obo/CL_0000842 mononuclear leukocyte A leukocyte with a single non-segmented nucleus in the mature form found in the circulatory pool of blood. http://purl.obolibrary.org/obo/GO_0045764 positive regulation of amino acid metabolic process http://purl.obolibrary.org/obo/GO_0009893 positive regulation of metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amino acid. http://purl.obolibrary.org/obo/CL_2000002 decidual cell http://purl.obolibrary.org/obo/CL_0000499 stromal cell A specialized, enlarged, connective tissue cell of the decidua with enlarged nucleus, dense membrane‐bound secretory granules and cytoplasmic accumulation of glycogen and lipid droplets. These cells develop by the transformation of endometrial stromal cells during decidualization. http://purl.obolibrary.org/obo/GO_0045778 positive regulation of ossification http://purl.obolibrary.org/obo/GO_0030278 regulation of ossification Any process that activates or increases the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance. http://purl.obolibrary.org/obo/CL_2000004 pituitary gland cell http://purl.obolibrary.org/obo/CL_0002319 neural cell Any cell that is part of a pituitary gland. http://purl.obolibrary.org/obo/GO_0045835 negative regulation of meiotic nuclear division http://purl.obolibrary.org/obo/GO_0010948 negative regulation of cell cycle process Any process that stops, prevents, or reduces the frequency, rate or extent of meiosis. http://purl.obolibrary.org/obo/CL_2000005 brain macroglial cell http://purl.obolibrary.org/obo/CL_0000126 macroglial cell Any macroglial cell that is part of a brain. http://purl.obolibrary.org/obo/GO_0045836 positive regulation of meiotic nuclear division http://purl.obolibrary.org/obo/GO_0090068 positive regulation of cell cycle process Any process that activates or increases the frequency, rate or extent of meiosis. http://purl.obolibrary.org/obo/CL_2000006 tonsil germinal center B cell http://purl.obolibrary.org/obo/CL_0000844 germinal center B cell Any germinal center B cell that is part of a tonsil. http://purl.obolibrary.org/obo/GO_0045840 positive regulation of mitotic nuclear division http://purl.obolibrary.org/obo/GO_0090068 positive regulation of cell cycle process Any process that activates or increases the frequency, rate or extent of mitosis. http://purl.obolibrary.org/obo/UBERON_0000007 pituitary gland http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure The pituitary gland is an endocrine gland that secretes hormones that regulate many other glands [GO]. An endocrine gland located ventral to the diencephalon and derived from mixed neuroectodermal and non neuroectodermal origin [ZFIN]. http://purl.obolibrary.org/obo/GO_0045926 negative regulation of growth http://purl.obolibrary.org/obo/GO_0048519 negative regulation of biological process Any process that stops, prevents or reduces the rate or extent of growth, the increase in size or mass of all or part of an organism. http://purl.obolibrary.org/obo/UBERON_0000010 peripheral nervous system http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision A major division of the nervous system that contains nerves which connect the central nervous system (CNS) with sensory organs, other organs, muscles, blood vessels and glands. http://purl.obolibrary.org/obo/GO_0045927 positive regulation of growth http://purl.obolibrary.org/obo/GO_0048518 positive regulation of biological process Any process that activates or increases the rate or extent of growth, the increase in size or mass of all or part of an organism. http://purl.obolibrary.org/obo/UBERON_0000014 zone of skin http://purl.obolibrary.org/obo/UBERON_0034944 zone of organ Any portion of the organ that covers that body and consists of a layer of epidermis and a layer of dermis. http://purl.obolibrary.org/obo/GO_0045947 negative regulation of translational initiation http://purl.obolibrary.org/obo/GO_0017148 negative regulation of translation Any process that stops, prevents, or reduces the frequency, rate or extent of translational initiation. http://purl.obolibrary.org/obo/UBERON_0000016 endocrine pancreas http://purl.obolibrary.org/obo/UBERON_0004119 endoderm-derived structure The part of the pancreas that is part of the endocrine system and is made up of islet cells, which produce insulin, glucagon and somatostatin. http://purl.obolibrary.org/obo/GO_0045948 positive regulation of translational initiation http://purl.obolibrary.org/obo/GO_0045727 positive regulation of translation Any process that activates or increases the frequency, rate or extent of translational initiation. http://purl.obolibrary.org/obo/UBERON_0000020 sense organ http://purl.obolibrary.org/obo/UBERON_0000062 organ An organ that is capable of transducing sensory stimulus to the nervous system. http://purl.obolibrary.org/obo/GO_0045980 negative regulation of nucleotide metabolic process http://purl.obolibrary.org/obo/GO_0045936 negative regulation of phosphate metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleotides. http://purl.obolibrary.org/obo/UBERON_0000029 lymph node http://purl.obolibrary.org/obo/UBERON_0005057 immune organ Any of the rounded masses of lymphoid tissue that are surrounded by a capsule of connective tissue, are distributed along the lymphatic vessels, and contain numerous lymphocytes which filter the flow of lymph. http://purl.obolibrary.org/obo/GO_0045981 positive regulation of nucleotide metabolic process http://purl.obolibrary.org/obo/GO_0045937 positive regulation of phosphate metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleotides. http://purl.obolibrary.org/obo/UBERON_0000056 ureter http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure Muscular duct that propels urine from the kidneys to the urinary bladder, or related organs. http://purl.obolibrary.org/obo/GO_0046364 monosaccharide biosynthetic process http://purl.obolibrary.org/obo/GO_0044283 small molecule biosynthetic process The chemical reactions and pathways resulting in the formation of monosaccharides, polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. http://purl.obolibrary.org/obo/UBERON_0000059 large intestine http://purl.obolibrary.org/obo/UBERON_0013765 digestive system element A subdivision of the digestive tract that connects the small intestine to the cloaca or anus. Lacks or has few villi[Kardong]. http://purl.obolibrary.org/obo/GO_0046459 short-chain fatty acid metabolic process http://purl.obolibrary.org/obo/GO_0006631 fatty acid metabolic process The chemical reactions and pathways involving a short-chain fatty acid. A short-chain fatty acid has an aliphatic tail containing fewer than 6 carbons. http://purl.obolibrary.org/obo/UBERON_0000065 respiratory tract http://purl.obolibrary.org/obo/UBERON_0001005 respiratory airway Anatomical structure that is part of the respiratory system. In mammals consists of upper and lower tracts. http://purl.obolibrary.org/obo/GO_0046660 female sex differentiation http://purl.obolibrary.org/obo/GO_0007548 sex differentiation The establishment of the sex of a female organism by physical differentiation. http://purl.obolibrary.org/obo/UBERON_0000159 anal canal http://purl.obolibrary.org/obo/UBERON_0004111 anatomical conduit The terminal part of the large intestine, continuous proximally with the rectum and distally terminates with the anus. http://purl.obolibrary.org/obo/GO_0046683 response to organophosphorus http://purl.obolibrary.org/obo/GO_0042221 response to chemical Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organophosphorus stimulus. Organophosphorus is a compound containing phosphorus bound to an organic molecule; several organophosphorus compounds are used as insecticides, and they are highly toxic cholinesterase inhibitors. http://purl.obolibrary.org/obo/UBERON_0000160 intestine http://purl.obolibrary.org/obo/UBERON_0004921 subdivision of digestive tract Segment of the alimentary canal extending from the stomach to the anus and, in humans and other mammals, consists of two segments, the small intestine and the large intestine. http://purl.obolibrary.org/obo/GO_0046887 positive regulation of hormone secretion http://purl.obolibrary.org/obo/GO_0010647 positive regulation of cell communication Any process that activates or increases the frequency, rate or extent of the regulated release of a hormone from a cell. http://purl.obolibrary.org/obo/UBERON_0000165 mouth http://purl.obolibrary.org/obo/UBERON_0004921 subdivision of digestive tract The proximal portion of the digestive tract, containing the oral cavity and bounded by the oral opening. In vertebrates, this extends to the pharynx and includes gums, lips, tongue and parts of the palate. Typically also includes the teeth, except where these occur elsewhere (e.g. pharyngeal jaws) or protrude from the mouth (tusks). http://purl.obolibrary.org/obo/GO_0046888 negative regulation of hormone secretion http://purl.obolibrary.org/obo/GO_0010648 negative regulation of cell communication Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a hormone from a cell. http://purl.obolibrary.org/obo/UBERON_0000167 oral cavity http://purl.obolibrary.org/obo/UBERON_0002553 anatomical cavity Anatomical cavity at the start of the digestive tract that that is enclosed by the mouth. The boundaries and contents vary depending on the species. In vertebrates, the boundaries are the oral opening, the cheeks, the palate and (if present) the palatoglossal arch - if this is not present then the mouth and pharynx form the oropharyngeal cavity. The buccal cavity contains the teeth, tongue and palate (when present). http://purl.obolibrary.org/obo/GO_0047497 mitochondrion transport along microtubule http://purl.obolibrary.org/obo/GO_0034643 establishment of mitochondrion localization, microtubule-mediated The directed movement of a mitochondrion along a microtubule, mediated by motor proteins. http://purl.obolibrary.org/obo/UBERON_0000178 blood http://purl.obolibrary.org/obo/UBERON_0000179 haemolymphatic fluid A fluid that is composed of blood plasma and erythrocytes. http://purl.obolibrary.org/obo/GO_0048020 CCR chemokine receptor binding http://purl.obolibrary.org/obo/GO_0042379 chemokine receptor binding Binding to a CCR chemokine receptor. http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure Multicellular, connected anatomical structure that has multiple organs as parts and whose parts work together to achieve some shared function. http://purl.obolibrary.org/obo/GO_0048483 autonomic nervous system development http://purl.obolibrary.org/obo/GO_0048731 system development The process whose specific outcome is the progression of the autonomic nervous system over time, from its formation to the mature structure. The autonomic nervous system is composed of neurons that are not under conscious control, and is comprised of two antagonistic components, the sympathetic and parasympathetic nervous systems. The autonomic nervous system regulates key functions including the activity of the cardiac (heart) muscle, smooth muscles (e.g. of the gut), and glands. http://purl.obolibrary.org/obo/UBERON_0000945 stomach http://purl.obolibrary.org/obo/UBERON_0010039 food storage organ An expanded region of the vertebrate alimentary tract that serves as a food storage compartment and digestive organ. A stomach is lined, in whole or in part by a glandular epithelium. http://purl.obolibrary.org/obo/GO_0048486 parasympathetic nervous system development http://purl.obolibrary.org/obo/GO_0048731 system development The process whose specific outcome is the progression of the parasympathetic nervous system over time, from its formation to the mature structure. The parasympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system. Parasympathetic nerves emerge cranially as pre ganglionic fibers from oculomotor, facial, glossopharyngeal and vagus and from the sacral region of the spinal cord. Most neurons are cholinergic and responses are mediated by muscarinic receptors. The parasympathetic system innervates, for example: salivary glands, thoracic and abdominal viscera, bladder and genitalia. http://purl.obolibrary.org/obo/UBERON_0000948 heart http://purl.obolibrary.org/obo/UBERON_0010314 structure with developmental contribution from neural crest A myogenic muscular circulatory organ found in the vertebrate cardiovascular system composed of chambers of cardiac muscle. It is the primary circulatory organ. http://purl.obolibrary.org/obo/GO_0048521 negative regulation of behavior http://purl.obolibrary.org/obo/GO_0050795 regulation of behavior Any process that stops, prevents, or reduces the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli. http://purl.obolibrary.org/obo/UBERON_0000949 endocrine system http://purl.obolibrary.org/obo/UBERON_0015204 glandular system Anatomical system that consists of the glands and parts of glands that produce endocrine secretions and help to integrate and control bodily metabolic activity. http://purl.obolibrary.org/obo/GO_0048534 hematopoietic or lymphoid organ development http://purl.obolibrary.org/obo/GO_0048513 animal organ development The process whose specific outcome is the progression of any organ involved in hematopoiesis (also known as hemopoiesis) or lymphoid cell activation over time, from its formation to the mature structure. Such development includes differentiation of resident cell types (stromal cells) and of migratory cell types dependent on the unique microenvironment afforded by the organ for their proper differentiation. http://purl.obolibrary.org/obo/UBERON_0000955 brain http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure The brain is the center of the nervous system in all vertebrate, and most invertebrate, animals. Some primitive animals such as jellyfish and starfish have a decentralized nervous system without a brain, while sponges lack any nervous system at all. In vertebrates, the brain is located in the head, protected by the skull and close to the primary sensory apparatus of vision, hearing, balance, taste, and smell[WP]. http://purl.obolibrary.org/obo/GO_0048545 response to steroid hormone http://purl.obolibrary.org/obo/GO_0033993 response to lipid Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a steroid hormone stimulus. http://purl.obolibrary.org/obo/UBERON_0000964 cornea http://purl.obolibrary.org/obo/UBERON_0010313 neural crest-derived structure The transparent anterior portion of the fibrous coat of the eye that serves as the chief refractory structure. http://purl.obolibrary.org/obo/GO_0048640 negative regulation of developmental growth http://purl.obolibrary.org/obo/GO_0048638 regulation of developmental growth Any process that stops, prevents, or reduces the frequency, rate or extent of developmental growth. http://purl.obolibrary.org/obo/UBERON_0000965 lens of camera-type eye http://purl.obolibrary.org/obo/UBERON_0005389 transparent eye structure A transparent and refractive lens located posterior to the iris. The lens of camera-type eye refracts light to be focused on the retina. http://purl.obolibrary.org/obo/GO_0048730 epidermis morphogenesis http://purl.obolibrary.org/obo/GO_0002009 morphogenesis of an epithelium The process in which the anatomical structures of the epidermis are generated and organized. The epidermis is the outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species. http://purl.obolibrary.org/obo/UBERON_0000966 retina http://purl.obolibrary.org/obo/UBERON_0005388 photoreceptor array The retina is the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates. http://purl.obolibrary.org/obo/GO_0048736 appendage development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of an appendage over time, from its formation to the mature structure. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch. http://purl.obolibrary.org/obo/UBERON_0000970 eye http://purl.obolibrary.org/obo/UBERON_0000020 sense organ An organ that detects light. http://purl.obolibrary.org/obo/GO_0048857 neural nucleus development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The biological process whose specific outcome is the progression of a neural nucleus from its initial condition to its mature state. A neural nucleus is an anatomical structure consisting of a discrete aggregate of neuronal soma. http://purl.obolibrary.org/obo/UBERON_0000977 pleura http://purl.obolibrary.org/obo/UBERON_0000042 serous membrane The invaginated serous membrane that surrounds the lungs (the visceral portion) and lines the walls of the pleural cavity (parietal portion). http://purl.obolibrary.org/obo/GO_0048860 glioblast division http://purl.obolibrary.org/obo/GO_0051301 cell division The process resulting in the physical partitioning and separation of a glioblast into daughter cells. http://purl.obolibrary.org/obo/UBERON_0000989 penis http://purl.obolibrary.org/obo/UBERON_0008811 intromittent organ An intromittent organ in certain biologically male organisms. In placental mammals, this also serves as the organ of urination. http://purl.obolibrary.org/obo/GO_0048909 anterior lateral line nerve development http://purl.obolibrary.org/obo/GO_0048892 lateral line nerve development The process whose specific outcome is the progression of the anterior lateral line nerve over time, form its formation to the mature structure. The anterior lateral line nerve contains efferent axons that innervate hair cells of the ALL and afferent axons that project to an octavolateralis column in the hindbrain. The octavolateralis column consists of the medial octavolateralis nucleus (MON), the caudal octavolateralis nucleus, and the magnocellular nucleus. http://purl.obolibrary.org/obo/UBERON_0000990 reproductive system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system Anatomical system that has as its parts the organs concerned with reproduction. http://purl.obolibrary.org/obo/GO_0048918 posterior lateral line nerve development http://purl.obolibrary.org/obo/GO_0048892 lateral line nerve development The process whose specific outcome is the progression of the posterior lateral line nerve over time, from its formation to the mature structure. The posterior lateral line nerve innervates hair cells of the PLL and projects to an octavolateralis column in the hindbrain that consists of the medial octavolateralis nucleus (MON), the caudal octavolateralis nucleus, and the magnocellular nucleus. http://purl.obolibrary.org/obo/UBERON_0000992 ovary http://purl.obolibrary.org/obo/UBERON_0003134 female reproductive organ The gonad of a female organism which contains germ cells. http://purl.obolibrary.org/obo/UBERON_0000995 uterus http://purl.obolibrary.org/obo/UBERON_0013515 subdivision of oviduct The female muscular organ of gestation in which the developing embryo or fetus is nourished until birth. http://purl.obolibrary.org/obo/GO_0050670 regulation of lymphocyte proliferation http://purl.obolibrary.org/obo/GO_0051249 regulation of lymphocyte activation Any process that modulates the frequency, rate or extent of lymphocyte proliferation. http://purl.obolibrary.org/obo/UBERON_0000996 vagina http://purl.obolibrary.org/obo/UBERON_0013515 subdivision of oviduct A fibromuscular tubular tract leading from the uterus to the exterior of the body in female placental mammals and marsupials, or to the cloaca in female birds, monotremes, and some reptiles[WP]. http://purl.obolibrary.org/obo/GO_0050671 positive regulation of lymphocyte proliferation http://purl.obolibrary.org/obo/GO_0051251 positive regulation of lymphocyte activation Any process that activates or increases the rate or extent of lymphocyte proliferation. http://purl.obolibrary.org/obo/UBERON_0000997 mammalian vulva http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure External genital organs of the female mammal[WP]. http://purl.obolibrary.org/obo/GO_0050672 negative regulation of lymphocyte proliferation http://purl.obolibrary.org/obo/GO_0051250 negative regulation of lymphocyte activation Any process that stops, prevents or reduces the rate or extent of lymphocyte proliferation. http://purl.obolibrary.org/obo/UBERON_0000998 seminal vesicle http://purl.obolibrary.org/obo/UBERON_0006868 seminal fluid secreting gland Either of a pair of glandular pouches that lie one on either side of the male reproductive tract posterolateral to the urinary bladder and in the human male secrete a sugar- and protein-containing fluid into the ejaculatory duct. http://purl.obolibrary.org/obo/GO_0050714 positive regulation of protein secretion http://purl.obolibrary.org/obo/GO_0051222 positive regulation of protein transport Any process that activates or increases the frequency, rate or extent of the controlled release of a protein from a cell. http://purl.obolibrary.org/obo/UBERON_0001004 respiratory system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system Functional system which consists of structures involved in respiration. http://purl.obolibrary.org/obo/GO_0050770 regulation of axonogenesis http://purl.obolibrary.org/obo/GO_0010975 regulation of neuron projection development Any process that modulates the frequency, rate or extent of axonogenesis, the generation of an axon, the long process of a neuron. http://purl.obolibrary.org/obo/UBERON_0001016 nervous system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system The nervous system is an organ system containing predominantly neuron and glial cells. In bilaterally symmetrical organism, it is arranged in a network of tree-like structures connected to a central body. The main functions of the nervous system are to regulate and control body functions, and to receive sensory input, process this information, and generate behavior [CUMBO]. http://purl.obolibrary.org/obo/GO_0050771 negative regulation of axonogenesis http://purl.obolibrary.org/obo/GO_0010977 negative regulation of neuron projection development Any process that stops, prevents, or reduces the frequency, rate or extent of axonogenesis. http://purl.obolibrary.org/obo/UBERON_0001017 central nervous system http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the neural tube derivatives: the brain and spinal cord. In invertebrates it includes central ganglia plus nerve cord. http://purl.obolibrary.org/obo/UBERON_0001032 sensory system http://purl.obolibrary.org/obo/UBERON_0015203 non-connected functional system Anatomical system that overlaps the nervous system and is responsible for receiving and processing sensory information. http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process Any process that modulates the frequency, rate or extent of development, the biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). http://purl.obolibrary.org/obo/UBERON_0001043 esophagus http://purl.obolibrary.org/obo/UBERON_0013765 digestive system element Tube that connects the pharynx to the stomach. In mammals, the oesophagus connects the buccal cavity with the stomach. The stratified squamous non-keratinised epithelium lining the buccal cavity is continued through the pharynx down into the oesophagus. The lowest part of the oesophagus (ca. 2 cm) is lined with gastric mucosa and covered by peritoneum. The main body of the oesophagus is lined with small, simple mucous glands. Each gland opens into the lumen by a long duct which pierces the muscularis mucosae (Wilson and Washington, 1989). A sphincter is situated at the point where the oesophagus enters the stomach to prevent gastro-oesophageal reflux, i.e. to prevent acidic gastric contents from reaching stratified epithelia of the oesophagus, where they can cause inflammation and irritation (Wilson and Washington, 1989; Brown et al., 1993). http://purl.obolibrary.org/obo/UBERON_0001044 saliva-secreting gland http://purl.obolibrary.org/obo/UBERON_0010047 oral gland Saliva-secreting exocrine glands of the oral cavity[GO]. http://purl.obolibrary.org/obo/GO_0050795 regulation of behavior http://purl.obolibrary.org/obo/GO_0051239 regulation of multicellular organismal process Any process that modulates the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli. http://purl.obolibrary.org/obo/UBERON_0001052 rectum http://purl.obolibrary.org/obo/UBERON_0004921 subdivision of digestive tract The terminal portion of the intestinal tube, terminating with the anus. http://purl.obolibrary.org/obo/GO_0050796 regulation of insulin secretion http://purl.obolibrary.org/obo/GO_0090276 regulation of peptide hormone secretion Any process that modulates the frequency, rate or extent of the regulated release of insulin. http://purl.obolibrary.org/obo/UBERON_0001091 calcareous tooth http://purl.obolibrary.org/obo/UBERON_0010314 structure with developmental contribution from neural crest Skeletal element within the mouth (or in some species, upper part of the digestive tract) that is composed of dentine and is used in procuring or masticating food. http://purl.obolibrary.org/obo/GO_0050804 modulation of chemical synaptic transmission http://purl.obolibrary.org/obo/GO_0099177 regulation of trans-synaptic signaling Any process that modulates the frequency or amplitude of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse. Amplitude, in this case, refers to the change in postsynaptic membrane potential due to a single instance of synaptic transmission. http://purl.obolibrary.org/obo/UBERON_0001103 diaphragm http://purl.obolibrary.org/obo/UBERON_0003831 respiratory system muscle A thin musculomebranous barrier that separates the abdominal and thoracic cavities. Often used for breathing control. http://purl.obolibrary.org/obo/GO_0050805 negative regulation of synaptic transmission http://purl.obolibrary.org/obo/GO_0010648 negative regulation of cell communication Any process that stops, prevents, or reduces the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse. http://purl.obolibrary.org/obo/UBERON_0001130 vertebral column http://purl.obolibrary.org/obo/UBERON_0000075 subdivision of skeletal system Subdivision of skeletal system that consists of all the vertebra and associated skeletal elements and joints in the body[modified from VSAO]. http://purl.obolibrary.org/obo/UBERON_0001132 parathyroid gland http://purl.obolibrary.org/obo/UBERON_0002368 endocrine gland The parathyroid gland is an endocrine gland for secretion of parathyroid hormone, usually found as a pair, embedded in the connective tissue capsule on the posterior surface of the thyroid gland. Parathyroid regulates calcium and phosphorous metabolism. http://purl.obolibrary.org/obo/GO_0050818 regulation of coagulation http://purl.obolibrary.org/obo/GO_0051239 regulation of multicellular organismal process Any process that modulates the frequency, rate or extent of coagulation, the process in which a fluid solution, or part of it, changes into a solid or semisolid mass. http://purl.obolibrary.org/obo/UBERON_0001134 skeletal muscle tissue http://purl.obolibrary.org/obo/UBERON_0002036 striated muscle tissue Muscle tissue that consists primarily of skeletal muscle fibers. http://purl.obolibrary.org/obo/UBERON_0001153 caecum http://purl.obolibrary.org/obo/UBERON_0009854 digestive tract diverticulum A pouch in the digestive tract that connects the ileum with the ascending colon of the large intestine. It is separated from the ileum by the ileocecal valve, and is the beginning of the large intestine. It is also separated from the colon by the cecocolic junction. http://purl.obolibrary.org/obo/GO_0050819 negative regulation of coagulation http://purl.obolibrary.org/obo/GO_0050818 regulation of coagulation Any process that stops, prevents, or reduces the frequency, rate or extent of coagulation. http://purl.obolibrary.org/obo/GO_0050820 positive regulation of coagulation http://purl.obolibrary.org/obo/GO_0050818 regulation of coagulation Any process that activates or increases the frequency, rate or extent of coagulation. http://purl.obolibrary.org/obo/GO_0050849 negative regulation of calcium-mediated signaling http://purl.obolibrary.org/obo/GO_1902532 negative regulation of intracellular signal transduction Any process that stops, prevents, or reduces the frequency, rate or extent of calcium-mediated signaling. http://purl.obolibrary.org/obo/UBERON_0001154 vermiform appendix http://purl.obolibrary.org/obo/UBERON_0013765 digestive system element A blind-ended tube connected to the cecum, from which it develops embryologically[WP]. http://purl.obolibrary.org/obo/GO_0050850 positive regulation of calcium-mediated signaling http://purl.obolibrary.org/obo/GO_1902533 positive regulation of intracellular signal transduction Any process that activates or increases the frequency, rate or extent of calcium-mediated signaling. http://purl.obolibrary.org/obo/GO_0050864 regulation of B cell activation http://purl.obolibrary.org/obo/GO_0051249 regulation of lymphocyte activation Any process that modulates the frequency, rate or extent of B cell activation. http://purl.obolibrary.org/obo/GO_0050869 negative regulation of B cell activation http://purl.obolibrary.org/obo/GO_0051250 negative regulation of lymphocyte activation Any process that stops, prevents, or reduces the frequency, rate or extent of B cell activation. http://purl.obolibrary.org/obo/UBERON_0001155 colon http://purl.obolibrary.org/obo/UBERON_0004921 subdivision of digestive tract A portion of the large intestine before it becomes the rectum. In mammals, the colon is the most part of the large intestine, excluding the vermiform appendix, the rectum and the anal canal. http://purl.obolibrary.org/obo/GO_0050870 positive regulation of T cell activation http://purl.obolibrary.org/obo/GO_0050863 regulation of T cell activation Any process that activates or increases the frequency, rate or extent of T cell activation. http://purl.obolibrary.org/obo/GO_0050871 positive regulation of B cell activation http://purl.obolibrary.org/obo/GO_0051251 positive regulation of lymphocyte activation Any process that activates or increases the frequency, rate or extent of B cell activation. http://purl.obolibrary.org/obo/UBERON_0001158 descending colon http://purl.obolibrary.org/obo/UBERON_0000168 proximal-distal subdivision of colon The portion of the colon between the left colic flexure and the sigmoid colon at the pelvic brim; the portion of the descending colon lying in the left iliac fossa is sometimes called the iliac colon. http://purl.obolibrary.org/obo/GO_0050884 neuromuscular process controlling posture http://purl.obolibrary.org/obo/GO_0050905 neuromuscular process Any process in which an organism voluntarily modulates its posture, the alignment of its anatomical parts. http://purl.obolibrary.org/obo/UBERON_0001159 sigmoid colon http://purl.obolibrary.org/obo/UBERON_0000168 proximal-distal subdivision of colon The part of the large intestine that is closest to the rectum and anus. It forms a loop that averages about 40 cm. in length, and normally lies within the pelvis, but on account of its freedom of movement it is liable to be displaced into the abdominal cavity. http://purl.obolibrary.org/obo/GO_0050931 pigment cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a pigmented cell, such as a melanocyte. http://purl.obolibrary.org/obo/UBERON_0001160 fundus of stomach http://purl.obolibrary.org/obo/UBERON_0009870 zone of stomach The fundus is the portion of the stomach that lies above the cardiac notch, and contains the fundic glands[GO, Kardong]. http://purl.obolibrary.org/obo/GO_0051017 actin filament bundle assembly http://purl.obolibrary.org/obo/GO_0022607 cellular component assembly The assembly of actin filament bundles; actin filaments are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness. http://purl.obolibrary.org/obo/UBERON_0001162 cardia of stomach http://purl.obolibrary.org/obo/UBERON_0009870 zone of stomach The part of the stomach attached to the esophagus. The cardia begins immediately distal to the z-line of the gastroeosphageal junction, where the squamous epithelium of the esophagus gives way to the columnar epithelium of the gastrointestinal tract[WP]. http://purl.obolibrary.org/obo/GO_0051054 positive regulation of DNA metabolic process http://purl.obolibrary.org/obo/GO_0051052 regulation of DNA metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving DNA. http://purl.obolibrary.org/obo/UBERON_0001165 pyloric antrum http://purl.obolibrary.org/obo/UBERON_0009870 zone of stomach The area at the bottom of the stomach on the caudal side of the pyloric canal that contains gastrin-producing G cells, which stimulate acid production, and the luminal pH-sensitive population of somatostatin-producing D cells. http://purl.obolibrary.org/obo/GO_0051099 positive regulation of binding http://purl.obolibrary.org/obo/GO_0051098 regulation of binding Any process that activates or increases the rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule. http://purl.obolibrary.org/obo/UBERON_0001166 pylorus http://purl.obolibrary.org/obo/UBERON_0009870 zone of stomach The stomach tissue region surrounding and controlling the distal outlet of the stomach, which opens into the duodenum. http://purl.obolibrary.org/obo/GO_0051100 negative regulation of binding http://purl.obolibrary.org/obo/GO_0051098 regulation of binding Any process that stops or reduces the rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule. http://purl.obolibrary.org/obo/UBERON_0001184 renal artery http://purl.obolibrary.org/obo/UBERON_0012254 abdominal aorta artery One of two laterally paired arteries that supplies the kidneys. These are large arteries that branch from the dorsal aorta in primitive vertebrates. http://purl.obolibrary.org/obo/GO_0051179 localization http://purl.obolibrary.org/obo/GO_0008150 biological_process Any process in which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported, tethered to or otherwise maintained in a specific location. In the case of substances, localization may also be achieved via selective degradation. http://purl.obolibrary.org/obo/UBERON_0001245 anus http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure Orifice at the opposite end of an animal's digestive tract from the mouth. Its function is to expel feces, unwanted semi-solid matter produced during digestion, which, depending on the type of animal, may be one or more of: matter which the animal cannot digest, such as bones; food material after all the nutrients have been extracted, for example cellulose or lignin; ingested matter which would be toxic if it remained in the digestive tract; and dead or excess gut bacteria and other endosymbionts. http://purl.obolibrary.org/obo/GO_0051223 regulation of protein transport http://purl.obolibrary.org/obo/GO_0051049 regulation of transport Any process that modulates the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/UBERON_0001255 urinary bladder http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure Distensible musculomembranous organ situated in the anterior part of the pelvic cavity in which urine collects before excretion[MP]. http://purl.obolibrary.org/obo/GO_0051235 maintenance of location http://purl.obolibrary.org/obo/GO_0051179 localization Any process in which a cell, substance or cellular entity, such as a protein complex or organelle, is maintained in a location and prevented from moving elsewhere. http://purl.obolibrary.org/obo/UBERON_0001257 trigone of urinary bladder http://purl.obolibrary.org/obo/UBERON_0000064 organ part The smooth triangular region of the wall of the urinary bladder formed by the two ureteral orifices and the internal urethral orifice; it is an area in which the muscle fibers are closely adherent to the mucosa. http://purl.obolibrary.org/obo/GO_0051246 regulation of protein metabolic process http://purl.obolibrary.org/obo/GO_0060255 regulation of macromolecule metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein. http://purl.obolibrary.org/obo/UBERON_0001258 neck of urinary bladder http://purl.obolibrary.org/obo/UBERON_0001560 neck of organ The constricted portion of the urinary bladder, formed by the meeting of its inferolateral surfaces proximal to the opening of the urethra[MP]. http://purl.obolibrary.org/obo/GO_0051247 positive regulation of protein metabolic process http://purl.obolibrary.org/obo/GO_0051246 regulation of protein metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein. http://purl.obolibrary.org/obo/UBERON_0001295 endometrium http://purl.obolibrary.org/obo/UBERON_0019042 reproductive system mucosa The glandular mucous membrane lining of the uterine cavity that is hormonally responsive during the estrous/menstrual cycle and during pregnancy. http://purl.obolibrary.org/obo/GO_0051248 negative regulation of protein metabolic process http://purl.obolibrary.org/obo/GO_0051246 regulation of protein metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of chemical reactions and pathways involving a protein. http://purl.obolibrary.org/obo/UBERON_0001299 glans penis http://purl.obolibrary.org/obo/UBERON_0035651 glans The conic expansion of the corpus spongiosum that forms the head of the penis. http://purl.obolibrary.org/obo/GO_0051249 regulation of lymphocyte activation http://purl.obolibrary.org/obo/GO_0002694 regulation of leukocyte activation Any process that modulates the frequency, rate or extent of lymphocyte activation. http://purl.obolibrary.org/obo/UBERON_0001301 epididymis http://purl.obolibrary.org/obo/UBERON_0005904 duct of male reproductive system The elongated structure connected to the posterior surface of the testis that transports, stores, and matures spermatozoa between testis and vas deferens. http://purl.obolibrary.org/obo/GO_0051250 negative regulation of lymphocyte activation http://purl.obolibrary.org/obo/GO_0051249 regulation of lymphocyte activation Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte activation. http://purl.obolibrary.org/obo/UBERON_0001322 sciatic nerve http://purl.obolibrary.org/obo/UBERON_0001021 nerve A large nerve that supplies nearly the whole of the skin of the leg, the muscles of the back of the thigh, and those of the leg and foot. It begins in the lower back and runs through the buttock and down the lower limb. http://purl.obolibrary.org/obo/GO_0051251 positive regulation of lymphocyte activation http://purl.obolibrary.org/obo/GO_0051249 regulation of lymphocyte activation Any process that activates or increases the frequency, rate or extent of lymphocyte activation. http://purl.obolibrary.org/obo/UBERON_0001323 tibial nerve http://purl.obolibrary.org/obo/UBERON_0003431 leg nerve The tibial nerve is a branch of the sciatic nerve. The tibial nerve passes through the popliteal fossa to pass below the arch of soleus. In the popliteal fossa the nerve gives off branches to gastrocnemius, popliteus, soleus and plantaris muscles, an articular branch to the knee joint, and a cutaneous branch that will become the sural nerve. The sural nerve is joined by fibres from the common peroneal nerve and runs down the calf to supply the lateral side of the foot. Below the soleus muscle the nerve lies close to the tibia and supplies the tibialis posterior, the flexor digitorum longus and the flexor hallucis longus. The nerve passes into the foot running posterior to the medial malleolus. Here it is bound down by the flexor retinaculum in company with the posterior tibial artery. [WP,unvetted]. http://purl.obolibrary.org/obo/GO_0051253 negative regulation of RNA metabolic process http://purl.obolibrary.org/obo/GO_0045934 negative regulation of nucleobase-containing compound metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving RNA. http://purl.obolibrary.org/obo/UBERON_0001361 femoral vein http://purl.obolibrary.org/obo/UBERON_0003516 hindlimb blood vessel In the human body, the femoral vein is a blood vessel that accompanies the femoral artery in the femoral sheath. It begins at the adductor canal (also known as Hunter's canal) and is a continuation of the popliteal vein. It ends at the inferior margin of the inguinal ligament, where it becomes the external iliac vein. [WP,unvetted]. http://purl.obolibrary.org/obo/GO_0051280 negative regulation of release of sequestered calcium ion into cytosol http://purl.obolibrary.org/obo/GO_0051279 regulation of release of sequestered calcium ion into cytosol Any process that stops, prevents, or reduces the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria. http://purl.obolibrary.org/obo/UBERON_0001558 lower respiratory tract http://purl.obolibrary.org/obo/UBERON_0000072 proximo-distal subdivision of respiratory tract The segment of the respiratory tract that starts proximally with the trachea and includes all distal structures including the lungs[WP,modified]. http://purl.obolibrary.org/obo/GO_0051281 positive regulation of release of sequestered calcium ion into cytosol http://purl.obolibrary.org/obo/GO_0051279 regulation of release of sequestered calcium ion into cytosol Any process that activates or increases the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria. http://purl.obolibrary.org/obo/UBERON_0001637 artery http://purl.obolibrary.org/obo/UBERON_0003509 arterial blood vessel An epithelial tube or tree of tibes that transports blood away from the heart[modified from AEO definition]. http://purl.obolibrary.org/obo/GO_0051418 microtubule nucleation by microtubule organizing center http://purl.obolibrary.org/obo/GO_0007020 microtubule nucleation The 'de novo' formation of a microtubule, mediated by the microtubule organizing center. http://purl.obolibrary.org/obo/UBERON_0001648 vestibulocochlear nerve http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure Cranial nerve that transmits sound and equilibrium (balance) information from the inner ear to the brain. http://purl.obolibrary.org/obo/GO_0051644 plastid localization http://purl.obolibrary.org/obo/GO_0051640 organelle localization Any process in which a plastid is transported to, and/or maintained in, a specific location within the cell. http://purl.obolibrary.org/obo/UBERON_0001650 hypoglossal nerve http://purl.obolibrary.org/obo/UBERON_0001785 cranial nerve Cranial nerve that innervates the muscles of the tongue. http://purl.obolibrary.org/obo/GO_0051647 nucleus localization http://purl.obolibrary.org/obo/GO_0051640 organelle localization Any process in which the nucleus is transported to, and/or maintained in, a specific location within the cell. http://purl.obolibrary.org/obo/UBERON_0001677 sphenoid bone http://purl.obolibrary.org/obo/UBERON_0015060 sphenoid endochondral element An unpaired bone situated at the base of the skull in front of the temporal bone and basilar part of the occipital bone. The sphenoid bone is one of the seven bones that articulate to form the orbit. Its shape somewhat resembles that of a butterfly or bat with its wings extended. http://purl.obolibrary.org/obo/GO_0051648 vesicle localization http://purl.obolibrary.org/obo/GO_0051640 organelle localization Any process in which a vesicle or vesicles are transported to, and/or maintained in, a specific location. http://purl.obolibrary.org/obo/UBERON_0001705 nail http://purl.obolibrary.org/obo/UBERON_0009564 distal limb integumentary appendage A horn-like keratin structure covering the dorsal aspect of the terminal phalanges of fingers and toes[WP]. http://purl.obolibrary.org/obo/GO_0051655 maintenance of vesicle location http://purl.obolibrary.org/obo/GO_0051648 vesicle localization Any process in which a vesicle is maintained in a specific location within a cell and prevented from moving elsewhere. http://purl.obolibrary.org/obo/UBERON_0001707 nasal cavity http://purl.obolibrary.org/obo/UBERON_0002553 anatomical cavity An anatomical cavity that is part of the olfactory apparatus. This includes the space bounded anteriorly by the nares and posteriorly by the choanae, when these structures are present. http://purl.obolibrary.org/obo/GO_0051656 establishment of organelle localization http://purl.obolibrary.org/obo/GO_0051640 organelle localization The directed movement of an organelle to a specific location. http://purl.obolibrary.org/obo/UBERON_0001708 jaw skeleton http://purl.obolibrary.org/obo/UBERON_0010912 subdivision of skeleton Subdivision of skeleton which includes upper and lower jaw skeletons. http://purl.obolibrary.org/obo/GO_0051668 localization within membrane http://purl.obolibrary.org/obo/GO_0051641 cellular localization Any process in which a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a membrane. http://purl.obolibrary.org/obo/UBERON_0001711 eyelid http://purl.obolibrary.org/obo/UBERON_0000064 organ part A fold of skin that covers and protects part of the eyeball. Examples: upper eyelid, lower eyelid, nictitating membrane. http://purl.obolibrary.org/obo/UBERON_0001723 tongue http://purl.obolibrary.org/obo/UBERON_0013765 digestive system element A muscular organ in the floor of the mouth. http://purl.obolibrary.org/obo/GO_0051674 localization of cell http://purl.obolibrary.org/obo/GO_0051179 localization Any process in which a cell is transported to, and/or maintained in, a specific location. http://purl.obolibrary.org/obo/GO_0051781 positive regulation of cell division http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the frequency, rate or extent of cell division. http://purl.obolibrary.org/obo/UBERON_0001736 submandibular gland http://purl.obolibrary.org/obo/UBERON_0001829 major salivary gland Either of the paired compound tubuloalveolar (aka tubuloacinar) major salivary glands composed of both serous and mucous secretory cells and situated beneath the mandible. http://purl.obolibrary.org/obo/GO_0051782 negative regulation of cell division http://purl.obolibrary.org/obo/GO_0051302 regulation of cell division Any process that stops, prevents, or reduces the frequency, rate or extent of cell division. http://purl.obolibrary.org/obo/UBERON_0001737 larynx http://purl.obolibrary.org/obo/UBERON_0000072 proximo-distal subdivision of respiratory tract A continuation of the pharynx that is involved in breathing, sound production, and protecting the trachea against food aspiration. http://purl.obolibrary.org/obo/GO_0051790 short-chain fatty acid biosynthetic process http://purl.obolibrary.org/obo/GO_0046459 short-chain fatty acid metabolic process The chemical reactions and pathways resulting in the formation of a short-chain fatty acid. A short-chain fatty acid has an aliphatic tail containing fewer than 6 carbons. http://purl.obolibrary.org/obo/UBERON_0001739 laryngeal cartilage http://purl.obolibrary.org/obo/UBERON_0011004 pharyngeal arch cartilage The cartilaginous structures that support the larynx. http://purl.obolibrary.org/obo/GO_0051861 glycolipid binding http://purl.obolibrary.org/obo/GO_0097367 carbohydrate derivative binding Binding to a glycolipid, any compound containing one or more monosaccharide residues bound by a glycosidic linkage to a hydrophobic group such as an acylglycerol, a sphingoid, a ceramide (N-acylsphingoid) or a prenyl phosphate. http://purl.obolibrary.org/obo/UBERON_0001750 lacrimal apparatus http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system A network of orbital structures of the eye that secrete and drain tears from the surface of the eyeball into the nasal cavity; these parts include the lacrimal glands, lacrimal lake, lacrimal ducts, lacrimal canals, lacrimal sacs, nasolacrimal ducts, and lacrimal puncta. http://purl.obolibrary.org/obo/GO_0051875 pigment granule localization http://purl.obolibrary.org/obo/GO_0051648 vesicle localization Any process in which a pigment granule is transported to, and/or maintained in, a specific location within the cell. http://purl.obolibrary.org/obo/UBERON_0001756 middle ear http://purl.obolibrary.org/obo/UBERON_0034921 multi organ part structure The middle ear is the air-filled cavity within the skull of vertebrates that lies between the outer ear and the inner ear. It is linked to the pharynx (and therefore to outside air) via the Eustachian tube and in mammals contains the three ear ossicles, which transmit auditory vibrations from the outer ear (via the tympanum) to the inner ear (via the oval window)[GO]. http://purl.obolibrary.org/obo/GO_0051904 pigment granule transport http://purl.obolibrary.org/obo/GO_0051905 establishment of pigment granule localization The directed movement of pigment granules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/UBERON_0001759 vagus nerve http://purl.obolibrary.org/obo/UBERON_0010314 structure with developmental contribution from neural crest Cranial nerve that branches into the lateral (to body sense organs) and the intestino-accessorial (to the skin, muscles of shoulder, hyoid, larynx, gut, lungs, and heart). http://purl.obolibrary.org/obo/GO_0051905 establishment of pigment granule localization http://purl.obolibrary.org/obo/GO_0051650 establishment of vesicle localization The directed movement of a pigment granule to a specific location. http://purl.obolibrary.org/obo/UBERON_0001776 optic choroid http://purl.obolibrary.org/obo/UBERON_0002203 vasculature of eye Vascular layer containing connective tissue, of the eye lying between the retina and the sclera. The choroid provides oxygen and nourishment to the outer layers of the retina. Along with the ciliary body and iris, the choroid forms the uveal tract[WP]. http://purl.obolibrary.org/obo/GO_0051932 synaptic transmission, GABAergic http://purl.obolibrary.org/obo/GO_0007268 chemical synaptic transmission The vesicular release of gamma-aminobutyric acid (GABA). from a presynapse, across a chemical synapse, the subsequent activation of GABA receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse. http://purl.obolibrary.org/obo/UBERON_0001811 conjunctiva http://purl.obolibrary.org/obo/UBERON_0000060 anatomical wall The mucous membrane that lines the inner surface of the eyelids and the front of the eyeball. http://purl.obolibrary.org/obo/GO_0051960 regulation of nervous system development http://purl.obolibrary.org/obo/GO_2000026 regulation of multicellular organismal development Any process that modulates the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue. http://purl.obolibrary.org/obo/UBERON_0001820 sweat gland http://purl.obolibrary.org/obo/UBERON_0019319 exocrine gland of integumental system Any of the coil glands of the skin that secrete sweat. http://purl.obolibrary.org/obo/GO_0051961 negative regulation of nervous system development http://purl.obolibrary.org/obo/GO_0051960 regulation of nervous system development Any process that stops, prevents, or reduces the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue. http://purl.obolibrary.org/obo/UBERON_0001831 parotid gland http://purl.obolibrary.org/obo/UBERON_0012102 buccal salivary gland The parotid gland is the largest of the salivary glands. It is found wrapped around the mandibular ramus, and it secretes saliva through Stensen's duct into the oral cavity, to facilitate mastication and swallowing. [WP,unvetted]. http://purl.obolibrary.org/obo/GO_0051962 positive regulation of nervous system development http://purl.obolibrary.org/obo/GO_0051960 regulation of nervous system development Any process that activates, maintains or increases the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue. http://purl.obolibrary.org/obo/UBERON_0001833 lip http://purl.obolibrary.org/obo/UBERON_0003102 surface structure One of the two fleshy folds which surround the opening of the mouth. http://purl.obolibrary.org/obo/GO_0051983 regulation of chromosome segregation http://purl.obolibrary.org/obo/GO_0010564 regulation of cell cycle process Any process that modulates the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets. http://purl.obolibrary.org/obo/UBERON_0001872 parietal lobe http://purl.obolibrary.org/obo/UBERON_0016526 lobe of cerebral hemisphere Upper central part of the cerebral hemisphere. (MSH). http://purl.obolibrary.org/obo/GO_0051985 negative regulation of chromosome segregation http://purl.obolibrary.org/obo/GO_0010948 negative regulation of cell cycle process Any process that stops, prevents, or reduces the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets. http://purl.obolibrary.org/obo/UBERON_0001961 mucosa-associated lymphoid tissue http://purl.obolibrary.org/obo/UBERON_0012069 epithelium-associated lymphoid tissue Diffuse system of small concentrations of lymphoid tissue found in various sites of the body such as the gastrointestinal tract, thyroid, breast, lung, salivary glands, eye, and skin[WP]. Mucosal-associated lymphoid tissue is typically found as nodules associated with mucosal epithelia with distinct internal structures including B- and T-zones for the activation of lymphocytes[GO]. http://purl.obolibrary.org/obo/GO_0055001 muscle cell development http://purl.obolibrary.org/obo/GO_0048468 cell development The process whose specific outcome is the progression of a muscle cell over time, from its formation to the mature structure. Muscle cell development does not include the steps involved in committing an unspecified cell to the muscle cell fate. http://purl.obolibrary.org/obo/UBERON_0001982 capillary http://purl.obolibrary.org/obo/UBERON_8410081 blood microvessel Any of the smallest blood vessels connecting arterioles with venules. http://purl.obolibrary.org/obo/GO_0055057 neuroblast division http://purl.obolibrary.org/obo/GO_0051301 cell division The process resulting in the physical partitioning and separation of a neuroblast into daughter cells. A neuroblast is any cell that will divide and give rise to a neuron. http://purl.obolibrary.org/obo/UBERON_0002012 pulmonary artery http://purl.obolibrary.org/obo/UBERON_0013768 great vessel of heart An artery that carries deoxygenated blood from heart to the lungs. They are the only arteries (other than umbilical arteries in the fetus) that carry deoxygenated blood.. http://purl.obolibrary.org/obo/GO_0055062 phosphate ion homeostasis http://purl.obolibrary.org/obo/GO_0098771 inorganic ion homeostasis Any process involved in the maintenance of an internal steady state of phosphate ions within an organism or cell. http://purl.obolibrary.org/obo/UBERON_0002046 thyroid gland http://purl.obolibrary.org/obo/UBERON_0010314 structure with developmental contribution from neural crest A two-lobed endocrine gland found in all vertebrates, located in front of and on either side of the trachea in humans, and producing various hormones, such as triiodothyronine and calcitonin[BTO]. http://purl.obolibrary.org/obo/UBERON_0002048 lung http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure Respiration organ that develops as an outpocketing of the esophagus. http://purl.obolibrary.org/obo/GO_0055075 potassium ion homeostasis http://purl.obolibrary.org/obo/GO_0098771 inorganic ion homeostasis Any process involved in the maintenance of an internal steady state of potassium ions within an organism or cell. http://purl.obolibrary.org/obo/UBERON_0002101 limb http://purl.obolibrary.org/obo/UBERON_0004708 paired limb/fin A paired appendage that is evolved from a paired fin. The extent of this structure includes autopod, stylopod and zeugopod regions when present, but excludes the girdle and its parts. http://purl.obolibrary.org/obo/GO_0055080 monoatomic cation homeostasis http://purl.obolibrary.org/obo/GO_0050801 monoatomic ion homeostasis Any process involved in the maintenance of an internal steady state of monoatomic cations within an organism or cell. Monatomic cations (also called simple cations) are cations consisting of exactly one atom. http://purl.obolibrary.org/obo/UBERON_0002106 spleen http://purl.obolibrary.org/obo/UBERON_0017672 abdominal viscera The organ that functions to filter blood and to store red corpuscles and platelets. http://purl.obolibrary.org/obo/GO_0055123 digestive system development http://purl.obolibrary.org/obo/GO_0048731 system development The process whose specific outcome is the progression of the digestive system over time, from its formation to the mature structure. The digestive system is the entire structure in which digestion takes place. Digestion is all of the physical, chemical, and biochemical processes carried out by multicellular organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism. http://purl.obolibrary.org/obo/UBERON_0002107 liver http://purl.obolibrary.org/obo/UBERON_0006925 digestive system gland An exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes[GO]. http://purl.obolibrary.org/obo/GO_0060019 radial glial cell differentiation http://purl.obolibrary.org/obo/GO_0010001 glial cell differentiation The process in which neuroepithelial cells of the neural tube give rise to radial glial cells, specialized bipotential progenitors cells of the brain. Differentiation includes the processes involved in commitment of a cell to a specific fate. http://purl.obolibrary.org/obo/UBERON_0002108 small intestine http://purl.obolibrary.org/obo/UBERON_0013765 digestive system element Subdivision of digestive tract that connects the stomach to the large intestine and is where much of the digestion and absorption of food takes place (with the exception of ruminants). The mammalian small intestine is long and coiled and can be differentiated histologically into: duodenum, jejunem, ileum[WP,cjm,Kardong]. http://purl.obolibrary.org/obo/GO_0060090 molecular adaptor activity http://purl.obolibrary.org/obo/GO_0003674 molecular_function The binding activity of a molecule that brings together two or more molecules through a selective, non-covalent, often stoichiometric interaction, permitting those molecules to function in a coordinated way. http://purl.obolibrary.org/obo/GO_0060142 regulation of syncytium formation by plasma membrane fusion http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells. http://purl.obolibrary.org/obo/UBERON_0002110 gallbladder http://purl.obolibrary.org/obo/UBERON_0017672 abdominal viscera An organ that aids digestion and stores bile produced by the liver[WP]. http://purl.obolibrary.org/obo/GO_0060143 positive regulation of syncytium formation by plasma membrane fusion http://purl.obolibrary.org/obo/GO_0051130 positive regulation of cellular component organization Any process that increases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells. http://purl.obolibrary.org/obo/UBERON_0002113 kidney http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure A paired organ of the urinary tract that produces urine and maintains bodily fluid homeostasis, blood pressure, pH levels, red blood cell production and skeleton mineralization. http://purl.obolibrary.org/obo/GO_0060170 ciliary membrane http://purl.obolibrary.org/obo/GO_0031253 cell projection membrane The portion of the plasma membrane surrounding a cilium. http://purl.obolibrary.org/obo/UBERON_0002114 duodenum http://purl.obolibrary.org/obo/UBERON_0004921 subdivision of digestive tract The first part of the small intestine. At the junction of the stomach and the duodenum the alimentary canal is inflected. The duodenum first goes anteriorly for a short distance, turns dorsally, and eventually caudally, thus it is a U-shaped structure with two horizontal sections (a ventral and a dorsal one). http://purl.obolibrary.org/obo/GO_0060896 neural plate pattern specification http://purl.obolibrary.org/obo/GO_0007389 pattern specification process The developmental process that results in the creation of defined areas or spaces within the neural plate to which cells respond and eventually are instructed to differentiate. http://purl.obolibrary.org/obo/UBERON_0002115 jejunum http://purl.obolibrary.org/obo/UBERON_0004921 subdivision of digestive tract The portion of the small intestine that extends from the duodenum to the ileum. http://purl.obolibrary.org/obo/GO_0060897 neural plate regionalization http://purl.obolibrary.org/obo/GO_0060896 neural plate pattern specification The pattern specification process that results in the subdivision of an axis or axes of the neural plate in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment. http://purl.obolibrary.org/obo/UBERON_0002116 ileum http://purl.obolibrary.org/obo/UBERON_0004921 subdivision of digestive tract The portion of the small intestine that extends from the jejunum to the colon. http://purl.obolibrary.org/obo/GO_0060986 endocrine hormone secretion http://purl.obolibrary.org/obo/GO_0046879 hormone secretion The regulated release of a hormone into the circulatory system. http://purl.obolibrary.org/obo/UBERON_0002165 endocardium http://purl.obolibrary.org/obo/UBERON_0005983 heart layer The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers[GO]. http://purl.obolibrary.org/obo/GO_0061036 positive regulation of cartilage development http://purl.obolibrary.org/obo/GO_0061035 regulation of cartilage development Any process that increases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate. http://purl.obolibrary.org/obo/UBERON_0002185 bronchus http://purl.obolibrary.org/obo/UBERON_0000117 respiratory tube The upper conducting airways of the lung; these airways arise from the terminus of the trachea. http://purl.obolibrary.org/obo/GO_0061037 negative regulation of cartilage development http://purl.obolibrary.org/obo/GO_0061035 regulation of cartilage development Any process that decreases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate. http://purl.obolibrary.org/obo/UBERON_0002204 musculoskeletal system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system Anatomical system that consists of the muscular and skeletal systems. http://purl.obolibrary.org/obo/GO_0061041 regulation of wound healing http://purl.obolibrary.org/obo/GO_1903034 regulation of response to wounding Any process that modulates the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury. http://purl.obolibrary.org/obo/UBERON_0002240 spinal cord http://purl.obolibrary.org/obo/UBERON_0010314 structure with developmental contribution from neural crest Part of the central nervous system located in the vertebral canal continuous with and caudal to the brain; demarcated from brain by plane of foramen magnum. It is composed of an inner core of gray matter in which nerve cells predominate, and an outer layer of white matter in which myelinated nerve fibers predominate, and surrounds the central canal. (CUMBO). http://purl.obolibrary.org/obo/GO_0061045 negative regulation of wound healing http://purl.obolibrary.org/obo/GO_0032102 negative regulation of response to external stimulus Any process that decreases the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury. http://purl.obolibrary.org/obo/UBERON_0002298 brainstem http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain Stalk-like part of the brain that includes amongst its parts the medulla oblongata of the hindbrain and the tegmentum of the midbrain[ZFA,MP,generalized]. http://purl.obolibrary.org/obo/GO_0061180 mammary gland epithelium development http://purl.obolibrary.org/obo/GO_0060429 epithelium development The process whose specific outcome is the progression of the mammary gland epithelium over time, from its formation to the mature structure. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk. http://purl.obolibrary.org/obo/UBERON_0002330 exocrine system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system Anatomical system that consists of the glands and parts of glands that produce exocrine secretions and help to integrate and control bodily metabolic activity. Exocrine glands are glands that secrete their products (hormones) into ducts (duct glands). They are the counterparts to endocrine glands, which secrete their products (hormones) directly into the bloodstream (ductless glands) or release hormones (paracrines) that affect only target cells nearby the release site. [Wikipedia]. http://purl.obolibrary.org/obo/GO_0061458 reproductive system development http://purl.obolibrary.org/obo/GO_0048731 system development The progression of the reproductive system over time from its formation to the mature structure. The reproductive system consists of the organs that function in reproduction. http://purl.obolibrary.org/obo/UBERON_0002336 corpus callosum http://purl.obolibrary.org/obo/UBERON_0005340 dorsal telencephalic commissure White matter structure containing massive numbers of commissural fibers connecting cortical areas in the two cerebral hemispheres. It is subdivided into a genu, a rostrum, a body, and a splenium. (MM). http://purl.obolibrary.org/obo/GO_0065010 extracellular membrane-bounded organelle http://purl.obolibrary.org/obo/GO_0043230 extracellular organelle Organized structure of distinctive morphology and function, bounded by a lipid bilayer membrane and occurring outside the cell. http://purl.obolibrary.org/obo/UBERON_0002351 sinoatrial node http://purl.obolibrary.org/obo/UBERON_0010131 conducting tissue of heart The part of the cardiac conduction system that controls the timing of heart muscle contraction. It relays electrical signals to the AV node[GO]. Subdivision of conducting system of heart at the junction of the right atrium and the superior vena cava, around the sinoatrial nodal branch of right coronary artery and is continuous with the internodal tract[FMA]. http://purl.obolibrary.org/obo/UBERON_0002358 peritoneum http://purl.obolibrary.org/obo/UBERON_0000042 serous membrane A serous membrane that lines the peritoneal cavity[VHOG,modified]. http://purl.obolibrary.org/obo/GO_0070167 regulation of biomineral tissue development http://purl.obolibrary.org/obo/GO_2000026 regulation of multicellular organismal development Any process that modulates the frequency, rate or extent of biomineral tissue development, the formation of hard tissues that consist mainly of inorganic compounds. http://purl.obolibrary.org/obo/UBERON_0002367 prostate gland http://purl.obolibrary.org/obo/UBERON_0010147 male accessory sex gland The prostate gland is a partly muscular, partly glandular body that is situated near the base of the mammalian male urethra and secretes an alkaline viscid fluid which is a major constituent of the ejaculatory fluid. http://purl.obolibrary.org/obo/GO_0070168 negative regulation of biomineral tissue development http://purl.obolibrary.org/obo/GO_0070167 regulation of biomineral tissue development Any process that stops, prevents, or reduces the frequency, rate or extent of biomineral tissue development, the formation of hard tissues that consist mainly of inorganic compounds. http://purl.obolibrary.org/obo/UBERON_0002368 endocrine gland http://purl.obolibrary.org/obo/UBERON_0002530 gland Endocrine glands are glands of the endocrine system that secrete their products directly into the circulatory system rather than through a duct.[WP, modified]. http://purl.obolibrary.org/obo/GO_0070169 positive regulation of biomineral tissue development http://purl.obolibrary.org/obo/GO_0070167 regulation of biomineral tissue development Any process that activates or increases the frequency, rate or extent of biomineral tissue development, the formation of hard tissues that consist mainly of inorganic compounds. http://purl.obolibrary.org/obo/UBERON_0002370 thymus http://purl.obolibrary.org/obo/UBERON_0005058 hemolymphoid system gland Anatomical structure of largely lymphoid tissue that functions in cell-mediated immunity by being the site where T cells develop. http://purl.obolibrary.org/obo/GO_0070405 ammonium ion binding http://purl.obolibrary.org/obo/GO_0043169 cation binding Binding to ammonium ions (NH4+). http://purl.obolibrary.org/obo/UBERON_0002372 tonsil http://purl.obolibrary.org/obo/UBERON_0001962 gut-associated lymphoid tissue Either of the two small almond-shaped masses of lymph tissue found on either side of the oropharynx. http://purl.obolibrary.org/obo/GO_0070542 response to fatty acid http://purl.obolibrary.org/obo/GO_0033993 response to lipid Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fatty acid stimulus. http://purl.obolibrary.org/obo/UBERON_0002384 connective tissue http://purl.obolibrary.org/obo/UBERON_0000479 tissue Tissue with cells that deposit non-polarized extracellular matrix including connective tissue fibers and ground substance. http://purl.obolibrary.org/obo/GO_0070587 regulation of cell-cell adhesion involved in gastrulation http://purl.obolibrary.org/obo/GO_0022407 regulation of cell-cell adhesion Any process that modulates the frequency, rate, or extent of attachment of a cell to another cell affecting gastrulation. http://purl.obolibrary.org/obo/UBERON_0002387 pes http://purl.obolibrary.org/obo/UBERON_0008784 lower limb segment Distal portion of the hind limb, including tarsal region, metatarsal region and digits. http://purl.obolibrary.org/obo/GO_0070633 transepithelial transport http://purl.obolibrary.org/obo/GO_0006810 transport The directed movement of a substance from one side of an epithelium to the other. http://purl.obolibrary.org/obo/UBERON_0002389 manual digit http://purl.obolibrary.org/obo/UBERON_0002544 digit A digit that is part of a manus (hand). http://purl.obolibrary.org/obo/GO_0070663 regulation of leukocyte proliferation http://purl.obolibrary.org/obo/GO_0042127 regulation of cell population proliferation Any process that modulates the frequency, rate or extent of leukocyte proliferation. http://purl.obolibrary.org/obo/UBERON_0002391 lymph http://purl.obolibrary.org/obo/UBERON_0000179 haemolymphatic fluid Lymph is the fluid that is formed when interstitial fluid enters the conduits of the lymphatic system through lymph capillaries[WP]. http://purl.obolibrary.org/obo/GO_0070664 negative regulation of leukocyte proliferation http://purl.obolibrary.org/obo/GO_0008285 negative regulation of cell population proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of leukocyte proliferation. http://purl.obolibrary.org/obo/UBERON_0002394 bile duct http://purl.obolibrary.org/obo/UBERON_0004119 endoderm-derived structure Any of the ducts that form the biliary tree, carrying bile from the liver to the small intestine. http://purl.obolibrary.org/obo/GO_0070665 positive regulation of leukocyte proliferation http://purl.obolibrary.org/obo/GO_0070663 regulation of leukocyte proliferation Any process that activates or increases the frequency, rate or extent of leukocyte proliferation. http://purl.obolibrary.org/obo/UBERON_0002398 manus http://purl.obolibrary.org/obo/UBERON_0008785 upper limb segment Distal segment of the fore limb, including carpal region, metacarpal region and digits. http://purl.obolibrary.org/obo/GO_0070828 heterochromatin organization http://purl.obolibrary.org/obo/GO_0006325 chromatin organization Any process that results in the specification, formation or maintenance of the physical structure of eukaryotic heterochromatin, a compact and highly condensed form of chromatin. http://purl.obolibrary.org/obo/UBERON_0002405 immune system http://purl.obolibrary.org/obo/UBERON_0015203 non-connected functional system Anatomical system that protects the body from foreign substances, cells, and tissues by producing the immune response and that includes especially the thymus, spleen, lymphoid tissue, lymphocytes including the B cells and T cells, and antibodies. http://purl.obolibrary.org/obo/GO_0071345 cellular response to cytokine stimulus http://purl.obolibrary.org/obo/GO_0034097 response to cytokine Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokine stimulus. http://purl.obolibrary.org/obo/UBERON_0002407 pericardium http://purl.obolibrary.org/obo/UBERON_0000481 multi-tissue structure The combination of pericardial sac (a double-walled sac containing the heart and the roots of the great vessels) plus fibrous pericardium. http://purl.obolibrary.org/obo/GO_0071375 cellular response to peptide hormone stimulus http://purl.obolibrary.org/obo/GO_0032870 cellular response to hormone stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide hormone stimulus. A peptide hormone is any of a class of peptides that are secreted into the blood stream and have endocrine functions in living animals. http://purl.obolibrary.org/obo/UBERON_0002410 autonomic nervous system http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision The autonomic nervous system is composed of neurons that are not under conscious control, and is comprised of two antagonistic components, the sympathetic and parasympathetic nervous systems. The autonomic nervous system regulates key functions including the activity of the cardiac (heart) muscle, smooth muscles (e.g. of the gut), and glands[GO]. http://purl.obolibrary.org/obo/GO_0071451 cellular response to superoxide http://purl.obolibrary.org/obo/GO_0071450 cellular response to oxygen radical Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a superoxide stimulus. Superoxide is the anion, oxygen-, formed by addition of one electron to dioxygen (O2) or any compound containing the superoxide anion. http://purl.obolibrary.org/obo/UBERON_0002416 integumental system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system Connected anatomical system that forms a barrier between an animal and its environment. In vertebrates, the integumental system consists of the epidermis, dermis plus associated glands and adnexa such as hair and scales. In invertebrates, the integumental system may include cuticle. http://purl.obolibrary.org/obo/GO_0071495 cellular response to endogenous stimulus http://purl.obolibrary.org/obo/GO_0009719 response to endogenous stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus arising within the organism. http://purl.obolibrary.org/obo/UBERON_0002446 patella http://purl.obolibrary.org/obo/UBERON_0011141 appendicular ossicle A large sesamoid bone found in the distal femur/proximal tibial region of the hindlimb of tetrapods. The patella is the attachment site for proximal hindlimb tendons.[PHENOSCAPE:ad]. http://purl.obolibrary.org/obo/GO_0071600 otic vesicle morphogenesis http://purl.obolibrary.org/obo/GO_0060562 epithelial tube morphogenesis The process in which the anatomical structures of the otic vesicle are generated and organized. The otic vesicle is a transient embryonic structure formed during development of the vertebrate inner ear. http://purl.obolibrary.org/obo/UBERON_0003126 trachea http://purl.obolibrary.org/obo/UBERON_0000117 respiratory tube The trachea is the portion of the airway that attaches to the bronchi as it branches [GO:dph]. http://purl.obolibrary.org/obo/GO_0071699 olfactory placode morphogenesis http://purl.obolibrary.org/obo/GO_0071697 ectodermal placode morphogenesis The process in which the anatomical structures of the olfactory placode are generated and organized. The olfactory placode is a thickening of the neural ectoderm in the head region of the vertebrate embryo which develops into the olfactory region of the nasal cavity. http://purl.obolibrary.org/obo/UBERON_0003133 reproductive organ http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure An organ involved in reproduction. http://purl.obolibrary.org/obo/UBERON_0003134 female reproductive organ http://purl.obolibrary.org/obo/UBERON_0003133 reproductive organ A female organ involved in reproduction. http://purl.obolibrary.org/obo/GO_0071706 tumor necrosis factor superfamily cytokine production http://purl.obolibrary.org/obo/GO_0001816 cytokine production The appearance of any member of the TNF superfamily due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. http://purl.obolibrary.org/obo/UBERON_0003135 male reproductive organ http://purl.obolibrary.org/obo/UBERON_0003133 reproductive organ A male organ involved in reproduction. http://purl.obolibrary.org/obo/GO_0071763 nuclear membrane organization http://purl.obolibrary.org/obo/GO_0061024 membrane organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear inner or outer membrane. http://purl.obolibrary.org/obo/UBERON_0003221 phalanx http://purl.obolibrary.org/obo/UBERON_0015023 phalanx endochondral element Endochondral bones that are often elongate and arranged in rows of articulating elements, and form the visible part of the digits. http://purl.obolibrary.org/obo/GO_0071825 protein-lipid complex organization http://purl.obolibrary.org/obo/GO_0043933 protein-containing complex organization Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein-lipid complex. http://purl.obolibrary.org/obo/UBERON_0003691 epidural space http://purl.obolibrary.org/obo/UBERON_0010276 space in vertebral column The outermost part of the spinal canal. It is the space within the canal (formed by the surrounding vertebrae) lying outside the dura mater. http://purl.obolibrary.org/obo/GO_0071826 protein-RNA complex organization http://purl.obolibrary.org/obo/GO_0043933 protein-containing complex organization Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a ribonucleoprotein complex. http://purl.obolibrary.org/obo/UBERON_0003703 extrahepatic bile duct http://purl.obolibrary.org/obo/UBERON_0002394 bile duct Passages external to the liver for the conveyance of bile. These include the common bile duct and the common hepatic duct. http://purl.obolibrary.org/obo/GO_0072006 nephron development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the nephron over time, from its formation to the mature structure. A nephron is the functional unit of the kidney. http://purl.obolibrary.org/obo/UBERON_0003728 mediastinum http://purl.obolibrary.org/obo/UBERON_0002553 anatomical cavity The central part of the thoracic cavity enclosed by the left and right pleurae. http://purl.obolibrary.org/obo/GO_0072384 organelle transport along microtubule http://purl.obolibrary.org/obo/GO_0051656 establishment of organelle localization The directed movement of an organelle along a microtubule, mediated by motor proteins. This process begins with the attachment of an organelle to a microtubule, and ends when the organelle reaches its final destination. http://purl.obolibrary.org/obo/UBERON_0003889 fallopian tube http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure Initial section of the oviduct through which the ova pass from the ovary to the uterus. http://purl.obolibrary.org/obo/GO_0090031 positive regulation of steroid hormone biosynthetic process http://purl.obolibrary.org/obo/GO_0046886 positive regulation of hormone biosynthetic process Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroid hormones,compounds with a 1, 2, cyclopentanoperhydrophenanthrene nucleus that act as hormones. http://purl.obolibrary.org/obo/UBERON_0003959 rete testis http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure An anastomosing network of delicate tubules located in the hilum of the testicle (mediastinum testis) that carries sperm from the seminiferous tubules to the vasa efferentia[WP]. http://purl.obolibrary.org/obo/GO_0090066 regulation of anatomical structure size http://purl.obolibrary.org/obo/GO_0065008 regulation of biological quality Any process that modulates the size of an anatomical structure. http://purl.obolibrary.org/obo/UBERON_0004117 pharyngeal pouch http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue An internal pocketing of pharyngeal endoderm that contacts a region of ectoderm (a pharyngeal cleft) and interdigitates in the anterior and posterior directions with the pharyngeal arches. http://purl.obolibrary.org/obo/GO_0090277 positive regulation of peptide hormone secretion http://purl.obolibrary.org/obo/GO_0090276 regulation of peptide hormone secretion Any process that increases the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules. http://purl.obolibrary.org/obo/UBERON_0004535 cardiovascular system http://purl.obolibrary.org/obo/UBERON_0010314 structure with developmental contribution from neural crest Anatomical system that has as its parts the heart and blood vessels. http://purl.obolibrary.org/obo/GO_0090303 positive regulation of wound healing http://purl.obolibrary.org/obo/GO_0061041 regulation of wound healing Any process that increases the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury. http://purl.obolibrary.org/obo/UBERON_0004913 hepatopancreatic ampulla http://purl.obolibrary.org/obo/UBERON_0002394 bile duct A dilation of the duodenal papilla that is the opening of the juncture of the common bile duct and the main pancreatic duct. http://purl.obolibrary.org/obo/GO_0090322 regulation of superoxide metabolic process http://purl.obolibrary.org/obo/GO_2000377 regulation of reactive oxygen species metabolic process Any process that modulates the rate, frequency, or extent of superoxide metabolism, the chemical reactions and pathways involving superoxide, the superoxide anion O2- (superoxide free radical), or any compound containing this species. http://purl.obolibrary.org/obo/UBERON_0005057 immune organ http://purl.obolibrary.org/obo/UBERON_0000062 organ An organ that is part of a immune system [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0097060 synaptic membrane http://purl.obolibrary.org/obo/GO_0098590 plasma membrane region A specialized area of membrane on either the presynaptic or the postsynaptic side of a synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell. http://purl.obolibrary.org/obo/UBERON_0005352 spermatic cord http://purl.obolibrary.org/obo/UBERON_0034921 multi organ part structure The cord-like structure in males comprising the vas deferens and associated tissue that runs from the abdomen down to each testis[MP]. http://purl.obolibrary.org/obo/GO_0097154 GABAergic neuron differentiation http://purl.obolibrary.org/obo/GO_0030182 neuron differentiation The process in which a neuroblast acquires the specialized structural and functional features of a GABAergic neuron. http://purl.obolibrary.org/obo/UBERON_0005409 alimentary part of gastrointestinal system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system The part of the digestive system that excludes the hepatobiliary system. http://purl.obolibrary.org/obo/GO_0097644 calcitonin family binding http://purl.obolibrary.org/obo/GO_0017046 peptide hormone binding Binding to a member of the calcitonin family (e.g. adrenomedullin, adrenomedullin 2 (intermedin), amylin, calcitonin and calcitonin gene-related peptides (CGRPs)). http://purl.obolibrary.org/obo/UBERON_0005610 iliac vein http://purl.obolibrary.org/obo/UBERON_0001638 vein Any of the three veins including the common, external and internal iliac veins. http://purl.obolibrary.org/obo/GO_0097708 intracellular vesicle http://purl.obolibrary.org/obo/GO_0031982 vesicle Any vesicle that is part of the intracellular region. http://purl.obolibrary.org/obo/UBERON_0006558 lymphatic part of lymphoid system http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision An organ system subdivision that is a network of vessels capable of removing accumulating protein and fluid from the interstitial space and returning it to the vascular space. In some species, this network is connected to the immune system via lymph nodes and lymphocyte-producing organs, with the whole being the lymphoid system. http://purl.obolibrary.org/obo/GO_0097722 sperm motility http://purl.obolibrary.org/obo/GO_0048870 cell motility Any process involved in the controlled movement of a sperm cell. http://purl.obolibrary.org/obo/GO_0097730 non-motile cilium http://purl.obolibrary.org/obo/GO_0005929 cilium A cilium which may have a variable array of axonemal microtubules but does not contain molecular motors. http://purl.obolibrary.org/obo/GO_0098711 iron ion import across plasma membrane http://purl.obolibrary.org/obo/GO_0098659 inorganic cation import across plasma membrane The directed movement of iron ions from outside of a cell, across the plasma membrane and into the cytosol. http://purl.obolibrary.org/obo/GO_0099501 exocytic vesicle membrane http://purl.obolibrary.org/obo/GO_0030658 transport vesicle membrane The lipid bilayer surrounding an exocytic vesicle. http://purl.obolibrary.org/obo/GO_0099503 secretory vesicle http://purl.obolibrary.org/obo/GO_0031410 cytoplasmic vesicle A cytoplasmic, membrane bound vesicle that is capable of fusing to the plasma membrane to release its contents into the extracellular space. http://purl.obolibrary.org/obo/GO_0099515 actin filament-based transport http://purl.obolibrary.org/obo/GO_0030705 cytoskeleton-dependent intracellular transport The transport of organelles or other particles from one location in the cell to another along actin filaments. http://purl.obolibrary.org/obo/GO_0099518 vesicle cytoskeletal trafficking http://purl.obolibrary.org/obo/GO_0030705 cytoskeleton-dependent intracellular transport The directed movement of a vesicle along a cytoskeletal fiber such as a microtubule or and actin filament, mediated by motor proteins. http://purl.obolibrary.org/obo/GO_1900046 regulation of hemostasis http://purl.obolibrary.org/obo/GO_0050878 regulation of body fluid levels Any process that modulates the frequency, rate or extent of hemostasis. http://purl.obolibrary.org/obo/GO_1900047 negative regulation of hemostasis http://purl.obolibrary.org/obo/GO_1900046 regulation of hemostasis Any process that stops, prevents or reduces the frequency, rate or extent of hemostasis. http://purl.obolibrary.org/obo/GO_1900048 positive regulation of hemostasis http://purl.obolibrary.org/obo/GO_1900046 regulation of hemostasis Any process that activates or increases the frequency, rate or extent of hemostasis. http://purl.obolibrary.org/obo/GO_1900371 regulation of purine nucleotide biosynthetic process http://purl.obolibrary.org/obo/GO_1900542 regulation of purine nucleotide metabolic process Any process that modulates the frequency, rate or extent of purine nucleotide biosynthetic processes. http://purl.obolibrary.org/obo/GO_1900372 negative regulation of purine nucleotide biosynthetic process http://purl.obolibrary.org/obo/GO_1900543 negative regulation of purine nucleotide metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of purine nucleotide biosynthetic processes. http://purl.obolibrary.org/obo/GO_1900373 positive regulation of purine nucleotide biosynthetic process http://purl.obolibrary.org/obo/GO_1900544 positive regulation of purine nucleotide metabolic process Any process that activates or increases the frequency, rate or extent of purine nucleotide biosynthetic processes. http://purl.obolibrary.org/obo/GO_1900542 regulation of purine nucleotide metabolic process http://purl.obolibrary.org/obo/GO_0006140 regulation of nucleotide metabolic process Any process that modulates the frequency, rate or extent of purine nucleotide metabolic process. http://purl.obolibrary.org/obo/UBERON_0006562 pharynx http://purl.obolibrary.org/obo/UBERON_0004921 subdivision of digestive tract The pharynx is the part of the digestive system immediately posterior to the mouth[GO]. http://purl.obolibrary.org/obo/GO_1900543 negative regulation of purine nucleotide metabolic process http://purl.obolibrary.org/obo/GO_1900542 regulation of purine nucleotide metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of purine nucleotide metabolic process. http://purl.obolibrary.org/obo/UBERON_0010011 collection of basal ganglia http://purl.obolibrary.org/obo/UBERON_0010009 aggregate regional part of brain Subcortical masses of gray matter in the forebrain and midbrain that are richly interconnected and so viewed as a functional system. The nuclei usually included are the caudate nucleus (caudoputamen in rodents), putamen, globus pallidus, substantia nigra (pars compacta and pars reticulata) and the subthalamic nucleus. Some also include the nucleus accumbens and ventral pallidum. http://purl.obolibrary.org/obo/GO_1900544 positive regulation of purine nucleotide metabolic process http://purl.obolibrary.org/obo/GO_1900542 regulation of purine nucleotide metabolic process Any process that activates or increases the frequency, rate or extent of purine nucleotide metabolic process. http://purl.obolibrary.org/obo/UBERON_0011374 prepuce http://purl.obolibrary.org/obo/UBERON_0034929 external soft tissue zone A retractable double-layered fold of skin and mucous membrane that covers the glans penis or clitoris. Glands may also be present. http://purl.obolibrary.org/obo/GO_1901020 negative regulation of calcium ion transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0032413 negative regulation of ion transmembrane transporter activity Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion transmembrane transporter activity. http://purl.obolibrary.org/obo/UBERON_0012332 broad ligament of uterus http://purl.obolibrary.org/obo/UBERON_0000211 ligament A broad fold of peritoneum that extends from the side of the uterus to the wall of the pelvis. http://purl.obolibrary.org/obo/GO_1901142 insulin metabolic process http://purl.obolibrary.org/obo/GO_0019538 protein metabolic process The chemical reactions and pathways involving insulin. http://purl.obolibrary.org/obo/UBERON_0016410 male breast http://purl.obolibrary.org/obo/UBERON_0000310 breast A breast that is part of a male organism. http://purl.obolibrary.org/obo/GO_1901161 primary amino compound catabolic process http://purl.obolibrary.org/obo/GO_0009056 catabolic process The chemical reactions and pathways resulting in the breakdown of primary amino compound. http://purl.obolibrary.org/obo/UBERON_0016435 chest wall http://purl.obolibrary.org/obo/UBERON_0000060 anatomical wall Subdivision of thorax which includes all structures from the skin to the costal pleura. Examples: There is only one chest wall. http://purl.obolibrary.org/obo/GO_1901652 response to peptide http://purl.obolibrary.org/obo/GO_0042221 response to chemical Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide stimulus. http://purl.obolibrary.org/obo/UBERON_0016525 frontal lobe http://purl.obolibrary.org/obo/UBERON_0016526 lobe of cerebral hemisphere Frontal lobe is the anterior-most of five lobes of the cerebral hemisphere. It is bounded by the central sulcus on its posterior border and by the longitudinal cerebral fissure on its medial border. http://purl.obolibrary.org/obo/GO_1901654 response to ketone http://purl.obolibrary.org/obo/GO_1901700 response to oxygen-containing compound A response that results in a state of tolerance to ketone. http://purl.obolibrary.org/obo/UBERON_0034940 venous sinus cavity http://purl.obolibrary.org/obo/UBERON_0010161 lumen of blood vessel An enlarged chamber in the blood sinus capable of accumulating a large volume of blood. http://purl.obolibrary.org/obo/GO_1901879 regulation of protein depolymerization http://purl.obolibrary.org/obo/GO_0043244 regulation of protein-containing complex disassembly Any process that modulates the frequency, rate or extent of protein depolymerization. http://purl.obolibrary.org/obo/UBERON_0034953 embryonic lymph sac http://purl.obolibrary.org/obo/UBERON_0007499 epithelial sac A population of lymphatic endothelial cell precursors that will form the lymph vessels. http://purl.obolibrary.org/obo/GO_1901881 positive regulation of protein depolymerization http://purl.obolibrary.org/obo/GO_0043243 positive regulation of protein-containing complex disassembly Any process that activates or increases the frequency, rate or extent of protein depolymerization. http://purl.obolibrary.org/obo/UBERON_0035014 functional part of brain http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain A brain region defined by functional criteria, e.g. auditory cortex, rather than by structural or histological criteria. http://purl.obolibrary.org/obo/GO_1902679 negative regulation of RNA biosynthetic process http://purl.obolibrary.org/obo/GO_0051253 negative regulation of RNA metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of RNA biosynthetic process. http://purl.obolibrary.org/obo/UBERON_0035045 parotid gland intralobular duct http://purl.obolibrary.org/obo/UBERON_0014719 intralobular duct Any of the tubular canals of the parotid gland located within the parenchymal (secretory) tissue i.e. within lobules; both intercalated and striated (secretory) ducts are intralobular ducts. http://purl.obolibrary.org/obo/GO_1902905 positive regulation of supramolecular fiber organization http://purl.obolibrary.org/obo/GO_0051130 positive regulation of cellular component organization Any process that activates or increases the frequency, rate or extent of supramolecular fiber organization. http://purl.obolibrary.org/obo/UBERON_0035048 parotid gland excretory duct http://purl.obolibrary.org/obo/UBERON_0035049 excretory duct of salivary gland Any of the interlobular excretory ducts of the parotid gland which are found in the connective tissue septa and formed by the union of several intralobular striated (secretory) ducts; ultimately, the excretory ducts of the parotid gland coalesce and form a single main excretory duct (Stensen's duct) that opens into the oral cavity; excretory ducts do not change the secretory product. http://purl.obolibrary.org/obo/GO_1903008 organelle disassembly http://purl.obolibrary.org/obo/GO_0022411 cellular component disassembly The disaggregation of an organelle into its constituent components. http://purl.obolibrary.org/obo/UBERON_0035076 parotid gland myoepithelium http://purl.obolibrary.org/obo/UBERON_0003360 epithelium of parotid gland Epithelium that consists of stellate-shaped contractile cells with long dendritic processes that surround the secretory acini and intercalated ducts of the parotid gland, usually found in the glandular epithelium as a thin layer above the basement membrane but generally beneath the luminal cells; they display features of both smooth muscle and epithelium, such as numerous microfilaments with focal densities in the cytoplasmic processes, and desmosomes which attach them to the epithelial cells; their functions include contraction when the gland is stimulated to secrete, compressing or reinforcing the underlying parenchymal cells, thus aiding in the expulsion of saliva and preventing damage to the other cells. http://purl.obolibrary.org/obo/GO_1903115 regulation of actin filament-based movement http://purl.obolibrary.org/obo/GO_0032970 regulation of actin filament-based process Any process that modulates the frequency, rate or extent of actin filament-based movement. http://purl.obolibrary.org/obo/UBERON_0035078 parotid gland interlobular duct http://purl.obolibrary.org/obo/UBERON_0035053 interlobular duct of salivary gland Any of the excretory ducts of the parotid gland which are found in the connective tissue septa i.e. between lobules. http://purl.obolibrary.org/obo/GO_1903131 mononuclear cell differentiation http://purl.obolibrary.org/obo/GO_0002521 leukocyte differentiation The process in which a relatively unspecialized cell acquires the specialized features of a mononuclear cell. http://purl.obolibrary.org/obo/UBERON_0035083 transverse process-bearing vertebra http://purl.obolibrary.org/obo/UBERON_0002412 vertebra A vertebra that has a transverse process. http://purl.obolibrary.org/obo/GO_1903314 regulation of nitrogen cycle metabolic process http://purl.obolibrary.org/obo/GO_0019222 regulation of metabolic process Any process that modulates the frequency, rate or extent of nitrogen cycle metabolic process. http://purl.obolibrary.org/obo/UBERON_0035102 transverse process of caudal vertebra http://purl.obolibrary.org/obo/UBERON_0001077 transverse process of vertebra A transverse process that is part of a caudal vertebra. http://purl.obolibrary.org/obo/GO_1903353 regulation of nucleus organization http://purl.obolibrary.org/obo/GO_0033043 regulation of organelle organization Any process that modulates the frequency, rate or extent of nucleus organization. http://purl.obolibrary.org/obo/GO_1903555 regulation of tumor necrosis factor superfamily cytokine production http://purl.obolibrary.org/obo/GO_0001817 regulation of cytokine production Any process that modulates the frequency, rate or extent of tumor necrosis factor superfamily cytokine production. http://purl.obolibrary.org/obo/UBERON_0035198 superficial lymphatic vessel http://purl.obolibrary.org/obo/UBERON_0001473 lymphatic vessel The tubules that carry lymph throughout the body that are just beneath the surface of the skin. http://purl.obolibrary.org/obo/GO_1903556 negative regulation of tumor necrosis factor superfamily cytokine production http://purl.obolibrary.org/obo/GO_1903555 regulation of tumor necrosis factor superfamily cytokine production Any process that stops, prevents or reduces the frequency, rate or extent of tumor necrosis factor superfamily cytokine production. http://purl.obolibrary.org/obo/GO_1903557 positive regulation of tumor necrosis factor superfamily cytokine production http://purl.obolibrary.org/obo/GO_1903555 regulation of tumor necrosis factor superfamily cytokine production Any process that activates or increases the frequency, rate or extent of tumor necrosis factor superfamily cytokine production. http://purl.obolibrary.org/obo/UBERON_0035545 deep lymphatic vessel http://purl.obolibrary.org/obo/UBERON_0001473 lymphatic vessel The tubules that carry lymph throughout the body that are in the interior of the body or limbs. http://purl.obolibrary.org/obo/GO_1903976 negative regulation of glial cell migration http://purl.obolibrary.org/obo/GO_1903975 regulation of glial cell migration Any process that stops, prevents or reduces the frequency, rate or extent of glial cell migration. http://purl.obolibrary.org/obo/GO_1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential http://purl.obolibrary.org/obo/GO_0022824 transmitter-gated monoatomic ion channel activity Any transmitter-gated ion channel activity that is involved in regulation of postsynaptic membrane potential. http://purl.obolibrary.org/obo/UBERON_0035549 vasculature of integument http://purl.obolibrary.org/obo/UBERON_0002049 vasculature The part of the circulatory system that lies within the subcutaneous tissue layers close to the surface of the skin. http://purl.obolibrary.org/obo/GO_1904936 interneuron migration http://purl.obolibrary.org/obo/GO_0001764 neuron migration The orderly movement of an interneuron from one site to another. http://purl.obolibrary.org/obo/UBERON_0035551 deep vasculature http://purl.obolibrary.org/obo/UBERON_0002049 vasculature The part of the circulatory system that lies deep beneath the subcutaneous tissue layers away from the surface of the skin. http://purl.obolibrary.org/obo/GO_1905268 negative regulation of chromatin organization http://purl.obolibrary.org/obo/GO_0051129 negative regulation of cellular component organization Any process that stops, prevents or reduces the frequency, rate or extent of chromatin organization. http://purl.obolibrary.org/obo/GO_1905269 positive regulation of chromatin organization http://purl.obolibrary.org/obo/GO_2001252 positive regulation of chromosome organization Any process that activates or increases the frequency, rate or extent of chromatin organization. http://purl.obolibrary.org/obo/GO_1905332 positive regulation of morphogenesis of an epithelium http://purl.obolibrary.org/obo/GO_1905330 regulation of morphogenesis of an epithelium Any process that activates or increases the frequency, rate or extent of morphogenesis of an epithelium. http://purl.obolibrary.org/obo/GO_1905879 regulation of oogenesis http://purl.obolibrary.org/obo/GO_2000241 regulation of reproductive process Any process that modulates the frequency, rate or extent of oogenesis. http://purl.obolibrary.org/obo/GO_1905880 negative regulation of oogenesis http://purl.obolibrary.org/obo/GO_2000242 negative regulation of reproductive process Any process that stops, prevents or reduces the frequency, rate or extent of oogenesis. http://purl.obolibrary.org/obo/GO_1905881 positive regulation of oogenesis http://purl.obolibrary.org/obo/GO_2000243 positive regulation of reproductive process Any process that activates or increases the frequency, rate or extent of oogenesis. http://purl.obolibrary.org/obo/GO_1990266 neutrophil migration http://purl.obolibrary.org/obo/GO_0097530 granulocyte migration The movement of a neutrophil within or between different tissues and organs of the body. http://purl.obolibrary.org/obo/UBERON_0035552 deep vein http://purl.obolibrary.org/obo/UBERON_0001638 vein A blood vessel carrying deoxygenated blood far beneath the skin usually accompanying an artery. http://purl.obolibrary.org/obo/GO_1990351 transporter complex http://purl.obolibrary.org/obo/GO_0032991 protein-containing complex A protein complex facilitating transport of molecules (proteins, small molecules, nucleic acids) into, out of or within a cell, or between cells. http://purl.obolibrary.org/obo/UBERON_0035597 profundal placode http://purl.obolibrary.org/obo/UBERON_0009955 neurogenic placode An embryonic structure positioned halfway between the prospective eye and ear, adjacent to the future midbrain-hindbrain boundary. The profundal and the trigeminal ganglia are separate distally but fused at their proximal end as they condense around NF stage 24. http://purl.obolibrary.org/obo/GO_1990904 ribonucleoprotein complex http://purl.obolibrary.org/obo/GO_0032991 protein-containing complex A macromolecular complex that contains both RNA and protein molecules. http://purl.obolibrary.org/obo/UBERON_0035642 laryngeal nerve http://purl.obolibrary.org/obo/UBERON_0001021 nerve Any nerve that innervates the larynx. http://purl.obolibrary.org/obo/GO_2000106 regulation of leukocyte apoptotic process http://purl.obolibrary.org/obo/GO_0042981 regulation of apoptotic process Any process that modulates the frequency, rate or extent of leukocyte apoptotic process. http://purl.obolibrary.org/obo/UBERON_0035648 nerve innervating pinna http://purl.obolibrary.org/obo/UBERON_0011779 nerve of head region Any nerve that innervates the pinna. http://purl.obolibrary.org/obo/GO_2000107 negative regulation of leukocyte apoptotic process http://purl.obolibrary.org/obo/GO_2000106 regulation of leukocyte apoptotic process Any process that stops, prevents, or reduces the frequency, rate or extent of leukocyte apoptotic process. http://purl.obolibrary.org/obo/GO_2000108 positive regulation of leukocyte apoptotic process http://purl.obolibrary.org/obo/GO_0043065 positive regulation of apoptotic process Any process that activates or increases the frequency, rate or extent of leukocyte apoptotic process. http://purl.obolibrary.org/obo/UBERON_0035775 submandibular region http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision The region between the mandible and the hyoid bone that contains the submandibular and sublingual glands, suprahyoid muscles, submandibular ganglion, and lingual artery. http://purl.obolibrary.org/obo/GO_2000145 regulation of cell motility http://purl.obolibrary.org/obo/GO_0040012 regulation of locomotion Any process that modulates the frequency, rate or extent of cell motility. http://purl.obolibrary.org/obo/UBERON_0035776 accessory ciliary ganglion http://purl.obolibrary.org/obo/UBERON_0035783 ganglion of ciliary nerve A parasympathetic ganglion located on the short ciliary nerve differentiated from the main ciliary ganglion by virtue of the fact that it had no root derived directly from the inferior trunk of the oculomotor nerve and it never attaches to this nerve. http://purl.obolibrary.org/obo/GO_2000146 negative regulation of cell motility http://purl.obolibrary.org/obo/GO_0040013 negative regulation of locomotion Any process that stops, prevents, or reduces the frequency, rate or extent of cell motility. http://purl.obolibrary.org/obo/GO_2000147 positive regulation of cell motility http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the frequency, rate or extent of cell motility. http://purl.obolibrary.org/obo/UBERON_0035783 ganglion of ciliary nerve http://purl.obolibrary.org/obo/UBERON_0001808 parasympathetic ganglion Any parasympathetic ganglion that extends fibers into the short ciliary nerve. Includes both the main and acccessory ciliary ganglia. http://purl.obolibrary.org/obo/GO_2000177 regulation of neural precursor cell proliferation http://purl.obolibrary.org/obo/GO_0042127 regulation of cell population proliferation Any process that modulates the frequency, rate or extent of neural precursor cell proliferation. http://purl.obolibrary.org/obo/CL_0003042 M9-OFF retinal ganglion cell http://purl.obolibrary.org/obo/CL_0003040 M9 retinal ganglion cell An M9 retinal ganglion cell with synaptic terminals in S4 that is depolarized by decreased illumination of their receptive field center http://purl.obolibrary.org/obo/GO_0110097 regulation of calcium import into the mitochondrion http://purl.obolibrary.org/obo/GO_1903169 regulation of calcium ion transmembrane transport Any process that modulates the frequency, rate or extent of calcium import into the mitochondrion. http://purl.obolibrary.org/obo/GO_2000278 regulation of DNA biosynthetic process http://purl.obolibrary.org/obo/GO_0051052 regulation of DNA metabolic process Any process that modulates the frequency, rate or extent of DNA biosynthetic process. http://purl.obolibrary.org/obo/GO_2000279 negative regulation of DNA biosynthetic process http://purl.obolibrary.org/obo/GO_2000278 regulation of DNA biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of DNA biosynthetic process. http://purl.obolibrary.org/obo/GO_0110098 positive regulation of calcium import into the mitochondrion http://purl.obolibrary.org/obo/GO_1904427 positive regulation of calcium ion transmembrane transport Any process that activates or increases the frequency, rate or extent of calcium import into the mitochondrion. http://purl.obolibrary.org/obo/GO_2000573 positive regulation of DNA biosynthetic process http://purl.obolibrary.org/obo/GO_2000278 regulation of DNA biosynthetic process Any process that activates or increases the frequency, rate or extent of DNA biosynthetic process. http://purl.obolibrary.org/obo/GO_0110099 negative regulation of calcium import into the mitochondrion http://purl.obolibrary.org/obo/GO_1903170 negative regulation of calcium ion transmembrane transport Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion import into the mitochondrion. http://purl.obolibrary.org/obo/GO_0110110 positive regulation of animal organ morphogenesis http://purl.obolibrary.org/obo/GO_2000027 regulation of animal organ morphogenesis Any process that activates or increases the frequency, rate or extent of animal organ morphogenesis. http://purl.obolibrary.org/obo/GO_2000649 regulation of sodium ion transmembrane transporter activity http://purl.obolibrary.org/obo/GO_1902305 regulation of sodium ion transmembrane transport Any process that modulates the frequency, rate or extent of sodium ion transmembrane transporter activity. http://purl.obolibrary.org/obo/GO_2000651 positive regulation of sodium ion transmembrane transporter activity http://purl.obolibrary.org/obo/GO_1902307 positive regulation of sodium ion transmembrane transport Any process that activates or increases the frequency, rate or extent of sodium ion transmembrane transporter activity. http://purl.obolibrary.org/obo/GO_0110111 negative regulation of animal organ morphogenesis http://purl.obolibrary.org/obo/GO_2000027 regulation of animal organ morphogenesis Any process that stops, prevents, or reduces the frequency, rate or extent of animal organ morphogenesis. http://purl.obolibrary.org/obo/GO_0140231 anterograde axonal transport of neurotransmitter receptor complex http://purl.obolibrary.org/obo/GO_0099641 anterograde axonal protein transport The directed movement of a neurotransmitter receptor complex along microtubules from the cell body toward the cell periphery in nerve cell axons. http://purl.obolibrary.org/obo/GO_2001251 negative regulation of chromosome organization http://purl.obolibrary.org/obo/GO_0010639 negative regulation of organelle organization Any process that stops, prevents or reduces the frequency, rate or extent of chromosome organization. http://purl.obolibrary.org/obo/GO_0150105 protein localization to cell-cell junction http://purl.obolibrary.org/obo/GO_1902414 protein localization to cell junction A process in which a protein is transported to, or maintained, in a location within a cell-cell junction. http://purl.obolibrary.org/obo/GO_2001252 positive regulation of chromosome organization http://purl.obolibrary.org/obo/GO_0010638 positive regulation of organelle organization Any process that activates or increases the frequency, rate or extent of chromosome organization. http://purl.obolibrary.org/obo/GO_0120305 regulation of pigmentation http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process Any process that modulates the frequency, rate or extent of the deposition or modulates the distribution of coloring matter in an organism. http://purl.obolibrary.org/obo/GO_2001259 positive regulation of cation channel activity http://purl.obolibrary.org/obo/GO_1904064 positive regulation of cation transmembrane transport Any process that activates or increases the frequency, rate or extent of cation channel activity. http://purl.obolibrary.org/obo/PATO_0070029 corticothalamic projecting http://purl.obolibrary.org/obo/PATO_0070033 neuron projection quality A neuron projection quality that is a characteristic of neurons with soma in the cerebral cortex and projections to the thalamus. http://purl.obolibrary.org/obo/GO_0034293 sexual sporulation http://purl.obolibrary.org/obo/GO_0043934 sporulation The formation of spores derived from the products of meiosis. http://purl.obolibrary.org/obo/PATO_0070031 corticomedulla projecting http://purl.obolibrary.org/obo/PATO_0070033 neuron projection quality A neuron projection quality that is a characteristic of neurons that project to the medulla oblongata from other brain regions. http://purl.obolibrary.org/obo/GO_0034295 basidiospore formation http://purl.obolibrary.org/obo/GO_0043935 sexual sporulation resulting in formation of a cellular spore The process in which spores form outside a specialized end cell known as a basidium. Basidia are characteristic of the basidiomycete fungi (phylum Basidiomycota), and give rise to spores that each contain a haploid nucleus that is the product of meiosis. The spores are usually attached to the basidium by short spikes called sterigmata (singular: sterigma). In most basidiomycetes there are four sterigmata (and four spores) to a basidium. http://purl.obolibrary.org/obo/PATO_0070034 intratelencephalic projecting http://purl.obolibrary.org/obo/PATO_0070033 neuron projection quality A neuron projection quality that is a characteristic of neurons with both soma and projections entirely within the telencephalon. http://purl.obolibrary.org/obo/GO_0034296 zygospore formation http://purl.obolibrary.org/obo/GO_0043935 sexual sporulation resulting in formation of a cellular spore The process in which zygospores are formed. Zygospores are characteristic of the zygomycete fungi (phylum Zygomycota) thick-walled and darkly colored, and usually heavily ornamented as well, with many spines or ridges. It is formed between two specialized organs called suspensors, which are themselves usually heavily ornamented, one from each mating partner. The zygospore forms between them and then breaks away. http://purl.obolibrary.org/obo/CL_4023088 large basket cell http://purl.obolibrary.org/obo/CL_2000086 neocortex basket cell A basket cell that is large, and typically ascends to give rise to many long horizontally and vertically projecting axon collaterals that traverse neighboring columns and can extend through all cortical layers. http://purl.obolibrary.org/obo/GO_0034306 regulation of sexual sporulation http://purl.obolibrary.org/obo/GO_0051445 regulation of meiotic cell cycle Any process that modulates the frequency, rate or extent of spore formation from the products of meiosis. An example of this is found in Saccharomyces cerevisiae. http://purl.obolibrary.org/obo/CL_4023050 L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex http://purl.obolibrary.org/obo/CL_4030065 L6 intratelencephalic projecting glutamatergic neuron An intratelencephalic-projecting glutamatergic neuron with a soma found in L6 of the primary motor cortex. These cells are short untufted pyramidal cells, which could be stellate or inverted. http://purl.obolibrary.org/obo/GO_0034330 cell junction organization http://purl.obolibrary.org/obo/GO_0016043 cellular component organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell junction. A cell junction is a specialized region of connection between two cells or between a cell and the extracellular matrix. http://purl.obolibrary.org/obo/CL_4023038 L6b glutamatergic cortical neuron http://purl.obolibrary.org/obo/CL_0010012 cerebral cortex neuron A glutamatergic neuron with a soma found in cortical layer 6b. They are transcriptomically related to corticothalamic-projecting neurons but have differential projections to the thalamus or anterior cingulate. http://purl.obolibrary.org/obo/CL_0009020 tuft cell of appendix http://purl.obolibrary.org/obo/CL_0002203 tuft cell of large intestine An intestinal tuft cell that is a part of a vermiform appendix. http://purl.obolibrary.org/obo/GO_0034349 glial cell apoptotic process http://purl.obolibrary.org/obo/GO_0006915 apoptotic process Any apoptotic process in a glial cell, a non-neuronal cell of the nervous system. http://purl.obolibrary.org/obo/GO_0034350 regulation of glial cell apoptotic process http://purl.obolibrary.org/obo/GO_0042981 regulation of apoptotic process Any process that modulates the frequency, rate, or extent of glial cell apoptotic process. http://purl.obolibrary.org/obo/CL_4030007 fallopian tube multiciliated epithelial cell http://purl.obolibrary.org/obo/CL_0005012 multiciliated epithelial cell A multi-ciliated epithelial cell that is part of the fallopian tube, mainly found on the apex of the mucosal folds. This cell exhibits a columnar shape with an oval nucleus and is characterized by the presence of cilia on its surface. The coordinated beating of these cilia, together with peristaltic contractions, contributes to the self-propulsion of spermatozoa, the transport of ovum during ovulation and the transport of the fertilized ovum to the intramural fallopian tube. http://purl.obolibrary.org/obo/GO_0034351 negative regulation of glial cell apoptotic process http://purl.obolibrary.org/obo/GO_0034350 regulation of glial cell apoptotic process Any process that stops, prevents, or reduces the frequency, rate, or extent of glial cell apoptotic process. http://purl.obolibrary.org/obo/CL_4023187 koniocellular cell http://purl.obolibrary.org/obo/CL_0012001 neuron of the forebrain A neuron with a small cell body that is located in a koniocellular layer of the lateral geniculate nucleus (LGN). http://purl.obolibrary.org/obo/GO_0034352 positive regulation of glial cell apoptotic process http://purl.obolibrary.org/obo/GO_0043065 positive regulation of apoptotic process Any process that activates or increases the frequency, rate, or extent of glial cell apoptotic process. http://purl.obolibrary.org/obo/UBERON_8440076 somatomotor area http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain A part of the cerebral cortex that comprises of the primary motor cortex and the premotor cortex. http://purl.obolibrary.org/obo/GO_0034390 smooth muscle cell apoptotic process http://purl.obolibrary.org/obo/GO_0010657 muscle cell apoptotic process Any apoptotic process in a smooth muscle cell. Smooth muscle consists of non-striated, elongated, spindle-shaped cell found lining the digestive tract, uterus, and blood vessels. http://purl.obolibrary.org/obo/CL_0003027 retinal ganglion cell D2 http://purl.obolibrary.org/obo/CL_0003001 bistratified retinal ganglion cell A bistratified retinal ganglion cell D cell that has medium dendritic arbor and a large dendritic field that terminates in S2 and S4. http://purl.obolibrary.org/obo/GO_0034391 regulation of smooth muscle cell apoptotic process http://purl.obolibrary.org/obo/GO_0010660 regulation of muscle cell apoptotic process Any process that modulates the frequency, rate, or extent of smooth muscle cell apoptotic process. http://purl.obolibrary.org/obo/CL_0004238 asymmetric bistratified amacrine cell http://purl.obolibrary.org/obo/CL_0004252 medium field retinal amacrine cell A bistratified amacrine cell with a medium dendritic field, a flat and sparse dendritic arbor, and post-synaptic terminals at the intersections of S1 and S2, and S3 and S4. http://purl.obolibrary.org/obo/GO_0034392 negative regulation of smooth muscle cell apoptotic process http://purl.obolibrary.org/obo/GO_0010656 negative regulation of muscle cell apoptotic process Any process that stops, prevents, or reduces the frequency, rate, or extent of smooth muscle cell apoptotic process. http://purl.obolibrary.org/obo/CL_0004137 retinal ganglion cell A2 inner http://purl.obolibrary.org/obo/CL_0004138 retinal ganglion cell A2 A retinal ganglion A2 cell with dendrites terminating in S4. http://purl.obolibrary.org/obo/GO_0034393 positive regulation of smooth muscle cell apoptotic process http://purl.obolibrary.org/obo/GO_0010661 positive regulation of muscle cell apoptotic process Any process that activates or increases the frequency, rate, or extent of smooth muscle cell apoptotic process. http://purl.obolibrary.org/obo/CL_0004233 DAPI-3 amacrine cell http://purl.obolibrary.org/obo/CL_0004252 medium field retinal amacrine cell An amacrine cell with a medium dendritic field and post-synaptic terminals that stratify at S2, with a second stratification that occurs in S3 and S4. This cell type releases the neurotransmitter glycine. http://purl.obolibrary.org/obo/GO_0034436 glycoprotein transport http://purl.obolibrary.org/obo/GO_1901264 carbohydrate derivative transport The directed movement of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/CL_0004221 flag A amacrine cell http://purl.obolibrary.org/obo/CL_4030028 glycinergic amacrine cell A flag amacrine cell with post-synaptic terminals in S2 and S3. This cell type releases the neurotransmitter glycine. http://purl.obolibrary.org/obo/GO_0034486 vacuolar transmembrane transport http://purl.obolibrary.org/obo/GO_0055085 transmembrane transport The process in which a solute is transported from one side of the vacuolar membrane to the other. http://purl.obolibrary.org/obo/CL_0003013 G10 retinal ganglion cell http://purl.obolibrary.org/obo/CL_0000740 retinal ganglion cell A mono-stratified retinal ganglion cell that has a large dendritic field, a medium dendritic arbor, and a long secondary dendrite shaft with post synaptic terminals in sublaminar layer S4. http://purl.obolibrary.org/obo/GO_0034488 basic amino acid transmembrane export from vacuole http://purl.obolibrary.org/obo/GO_1990822 basic amino acid transmembrane transport The directed movement of basic amino acids out of the vacuole, across the vacuolar membrane. http://purl.obolibrary.org/obo/CL_0004228 broad diffuse amacrine cell http://purl.obolibrary.org/obo/CL_0004251 narrow field retinal amacrine cell An amacrine cell with a small dendritic field that has post-synaptic terminals in S1, S2, S3, and S4. http://purl.obolibrary.org/obo/GO_0034489 neutral amino acid transmembrane export from vacuole http://purl.obolibrary.org/obo/GO_0032974 amino acid transmembrane export from vacuole The directed movement of neutral amino acids out of the vacuole, across the vacuolar membrane. http://purl.obolibrary.org/obo/CL_4033017 bronchiolar smooth muscle cell http://purl.obolibrary.org/obo/CL_0019019 tracheobronchial smooth muscle cell A smooth muscle cell that is part of a bronchiole. http://purl.obolibrary.org/obo/GO_0034490 basic amino acid transmembrane import into vacuole http://purl.obolibrary.org/obo/GO_1990822 basic amino acid transmembrane transport The directed movement of basic amino acids into the vacuole across the vacuolar membrane. http://purl.obolibrary.org/obo/UBERON_8600023 placental villous stroma http://purl.obolibrary.org/obo/UBERON_0003891 stroma A stroma that is part of a chorionic villus (placental villus). A placental villous stroma supports the fetal capillaries and villous trophoblast. http://purl.obolibrary.org/obo/GO_0034491 neutral amino acid transmembrane import into vacuole http://purl.obolibrary.org/obo/GO_0032975 amino acid transmembrane import into vacuole The directed movement of neutral amino acids into the vacuole across the vacuolar membrane. http://purl.obolibrary.org/obo/UBERON_8600034 jejunum lamina propria http://purl.obolibrary.org/obo/UBERON_0001238 lamina propria of small intestine A lamina propria that is part of a jejunum. http://purl.obolibrary.org/obo/GO_0034502 protein localization to chromosome http://purl.obolibrary.org/obo/GO_0033365 protein localization to organelle Any process in which a protein is transported to, or maintained at, a specific location on a chromosome. http://purl.obolibrary.org/obo/UBERON_8600035 ileum lamina propria http://purl.obolibrary.org/obo/UBERON_0001238 lamina propria of small intestine A lamina propria that is part of an ileum. http://purl.obolibrary.org/obo/GO_0034505 tooth mineralization http://purl.obolibrary.org/obo/GO_0031214 biomineral tissue development The process in which calcium salts are deposited into calcareous tooth structures such as dental enamel, dentin and cementum. http://purl.obolibrary.org/obo/UBERON_8600039 chorionic villous mesenchyme http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue A mesenchyme that is part of a chorionic villus. http://purl.obolibrary.org/obo/GO_0034614 cellular response to reactive oxygen species http://purl.obolibrary.org/obo/GO_1901701 cellular response to oxygen-containing compound Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals. http://purl.obolibrary.org/obo/UBERON_8600042 endometrial lymphatic vessel http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure A lymphatic vessel that is part of an endometrium. http://purl.obolibrary.org/obo/GO_0034642 mitochondrion migration along actin filament http://purl.obolibrary.org/obo/GO_0051654 establishment of mitochondrion localization The directed movement of a mitochondrion along a microfilament, mediated by motor proteins. http://purl.obolibrary.org/obo/CL_0008040 squamous endothelial cell of venule http://purl.obolibrary.org/obo/CL_1000414 endothelial cell of venule An endothelial cell of the venule that is squamous shaped. This is in contrast to the cubodial shape of high endothelial venule cells. http://purl.obolibrary.org/obo/GO_0034643 establishment of mitochondrion localization, microtubule-mediated http://purl.obolibrary.org/obo/GO_0051654 establishment of mitochondrion localization The directed movement of the mitochondrion to a specific location, by a process involving microtubules. http://purl.obolibrary.org/obo/CL_4033066 pre-granulosa cell http://purl.obolibrary.org/obo/CL_0000630 supporting cell A supporting cell that is part of the ovary and differentiates into a granulosa cell. A pre-granulosa cell develops from an early supporting gonadal cell by repressing testis determination, which can then proliferate to form primordial follicles. http://purl.obolibrary.org/obo/GO_0034672 anterior/posterior pattern specification involved in pronephros development http://purl.obolibrary.org/obo/GO_0009952 anterior/posterior pattern specification The developmental process that results in the creation of defined areas or spaces within the pronephros along the anterior/posterior axis to which cells respond and eventually are instructed to differentiate. http://purl.obolibrary.org/obo/CL_4033067 mural granulosa cell http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure A follicular cell of ovary that differentiates from a cuboidal granulosa cell during the secondary follicle stage. Mural granulosa cells line the inner surface of the follicle wall, surrounding the fluid-filled antral cavity. These cells produce oestrogen during the follicular phase in response to follicle-stimulating hormone (FSH), and progesterone after ovulation in response to luteinizing hormone (LH). http://purl.obolibrary.org/obo/GO_0034756 regulation of iron ion transport http://purl.obolibrary.org/obo/GO_0010959 regulation of metal ion transport Any process that modulates the frequency, rate or extent of the directed movement of iron ions (Fe) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/CL_4042012 L2 marginal neuron http://purl.obolibrary.org/obo/CL_4030060 L2 intratelencephalic projecting glutamatergic neuron An L2 intratelencephalic projecting glutamatergic neuron with a soma on the L1-L2 border. This neuron type has small apical dendrites projecting to L1. http://purl.obolibrary.org/obo/GO_0034757 negative regulation of iron ion transport http://purl.obolibrary.org/obo/GO_0043271 negative regulation of monoatomic ion transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of iron ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/CL_4042013 Lamp5 Lhx6 neuron http://purl.obolibrary.org/obo/CL_4023069 medial ganglionic eminence derived GABAergic interneuron A transcriptomically distinct GABAergic interneuron marked by Lamp5 and Lhx6 expression, derived from the Medial Ganglionic Eminence (MGE), and located in the pallium. http://purl.obolibrary.org/obo/UBERON_8910000 stomatogastric nervous system http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision The part of the nervous system that controls the stomach, such as in crabs, lobsters, and flies http://purl.obolibrary.org/obo/GO_0034758 positive regulation of iron ion transport http://purl.obolibrary.org/obo/GO_0043270 positive regulation of monoatomic ion transport Any process that activates or increases the frequency, rate or extent of the directed movement of iron ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/CL_4307052 Astro-OLF NN_1 Stk32a astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301596 Astro-OLF NN_1 astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Aqp4 (Mmus), Prss23 (Mmus), Stk32a (Mmus). It is distinguished from other Astro-OLF NN_1 cells by expression of Stk32a. These cells are located in the Olfactory areas, brain , in or close to the regions: olfactory nerve layer of main olfactory bulb, Main olfactory bulb . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5232 Astro-OLF NN_1. http://purl.obolibrary.org/obo/CL_4307035 Astro-NT NN_2 Sez6l astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301590 Astro-NT NN_2 astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gja1 (Mmus), A330076C08Rik (Mmus), Otx2 (Mmus), Unc13c (Mmus). It is distinguished from other Astro-NT NN_2 cells by expression of Sez6l, Unc13c. These cells are located in the Thalamus , in or close to the regions: Posterior complex of the thalamus, Ventral posteromedial nucleus of the thalamus . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5215 Astro-NT NN_2. http://purl.obolibrary.org/obo/GO_0034759 regulation of iron ion transmembrane transport http://purl.obolibrary.org/obo/GO_1904062 regulation of monoatomic cation transmembrane transport Any process that modulates the frequency, rate or extent of the directed movement of iron ions (Fe) from one side of a membrane to the other by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/CL_4300366 oligodendrocyte precursor cell (Mmus) http://purl.obolibrary.org/obo/CL_4300031 OPC-Oligo cell (Mmus) A oligodendrocyte precursor cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Pdgfra (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Subclass:326 OPC NN. http://purl.obolibrary.org/obo/CL_4300349 Purkinje layer interneuron (Mmus) http://purl.obolibrary.org/obo/CL_4072102 Purkinje layer interneuron A Purkinje layer interneuron of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Rgs6 (Mmus), Slc6a5 (Mmus), Shisa9 (Mmus), Zic1 (Mmus), Bmp6 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Subclass:309 CB PLI Gly-Gaba. http://purl.obolibrary.org/obo/GO_0034760 negative regulation of iron ion transmembrane transport http://purl.obolibrary.org/obo/GO_1904063 negative regulation of cation transmembrane transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of iron ions from one side of a membrane to the other by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/CL_4301584 CB Granule Glut_1 cerebellar granule cell (Mmus) http://purl.obolibrary.org/obo/CL_4300354 cerebellar granule cell (Mmus) A cerebellar granule cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gabra6 (Mmus), Lmx1a (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1154 CB Granule Glut_1. http://purl.obolibrary.org/obo/CL_4301575 Lugaro cell (Mmus) http://purl.obolibrary.org/obo/CL_4300349 Purkinje layer interneuron (Mmus) A Lugaro cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Pthlh (Mmus), Tfap2b (Mmus), Rspo2 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1145 CB PLI Gly-Gaba_2. http://purl.obolibrary.org/obo/CL_4307095 COP NN_1 Bmp4 committed oligodendrocyte precursor (Mmus) http://purl.obolibrary.org/obo/CL_4301611 commited oligodendrocyte precursor (Mmus) A committed oligodendrocyte precursor of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of 9630013A20Rik (Mmus), Bmp4 (Mmus), Mob3b (Mmus). It is distinguished from other COP NN_1 cells by expression of Bmp4, Mob3b. These cells are located in the brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5275 COP NN_1. http://purl.obolibrary.org/obo/GO_0034761 positive regulation of iron ion transmembrane transport http://purl.obolibrary.org/obo/GO_1904064 positive regulation of cation transmembrane transport Any process that activates or increases the frequency, rate or extent of the directed movement of iron ions from one side of a membrane to the other by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/CL_4300028 cerebellar GABAergic neuron (Mmus) http://purl.obolibrary.org/obo/CL_1001611 cerebellar neuron A cerebellar neuron of the Mus musculus brain. Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Class:28 CB GABA. http://purl.obolibrary.org/obo/GO_0004518 nuclease activity http://purl.obolibrary.org/obo/GO_0140640 catalytic activity, acting on a nucleic acid Catalysis of the cleavage of ester linkages within nucleic acids. http://purl.obolibrary.org/obo/GO_0004536 DNA nuclease activity http://purl.obolibrary.org/obo/GO_0140097 catalytic activity, acting on DNA Catalysis of the cleavage of ester linkages within deoxyribonucleic acid. http://purl.obolibrary.org/obo/GO_0034763 negative regulation of transmembrane transport http://purl.obolibrary.org/obo/GO_0051051 negative regulation of transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0004925 prolactin receptor activity http://purl.obolibrary.org/obo/GO_0004896 cytokine receptor activity Combining with prolactin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. http://purl.obolibrary.org/obo/GO_0004948 calcitonin receptor activity http://purl.obolibrary.org/obo/GO_0097642 calcitonin family receptor activity Combining with calcitonin and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. http://purl.obolibrary.org/obo/GO_0004951 cholecystokinin receptor activity http://purl.obolibrary.org/obo/GO_0008528 G protein-coupled peptide receptor activity Combining with cholecystokinin and transmitting the signal across the membrane by activating an associated G-protein to initiate a change in cell activity. Cholecystokinin can act as a neuropeptide or as a gastrointestinal hormone. http://purl.obolibrary.org/obo/GO_0034764 positive regulation of transmembrane transport http://purl.obolibrary.org/obo/GO_0051050 positive regulation of transport Any process that activates or increases the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0004966 galanin receptor activity http://purl.obolibrary.org/obo/GO_0008188 neuropeptide receptor activity Combining with galanin to initiate a change in cell activity. http://purl.obolibrary.org/obo/GO_0004967 glucagon receptor activity http://purl.obolibrary.org/obo/GO_0008528 G protein-coupled peptide receptor activity Combining with glucagon and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. http://purl.obolibrary.org/obo/GO_0004969 histamine receptor activity http://purl.obolibrary.org/obo/GO_0008227 G protein-coupled amine receptor activity Combining with histamine to initiate a change in cell activity. Histamine is a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans. http://purl.obolibrary.org/obo/GO_0034769 basement membrane disassembly http://purl.obolibrary.org/obo/GO_0022617 extracellular matrix disassembly The controlled breakdown of the basement membrane in the context of a normal process such as imaginal disc eversion. http://purl.obolibrary.org/obo/GO_0004970 glutamate-gated receptor activity http://purl.obolibrary.org/obo/GO_0015171 amino acid transmembrane transporter activity Catalysis of the transmembrane transfer of an ion by a channel that opens when glutamate has been bound by the channel complex or one of its constituent parts. http://purl.obolibrary.org/obo/GO_0004977 melanocortin receptor activity http://purl.obolibrary.org/obo/GO_0008528 G protein-coupled peptide receptor activity Combining with melanocortin to initiate a change in cell activity. http://purl.obolibrary.org/obo/GO_0034776 response to histamine http://purl.obolibrary.org/obo/GO_1901698 response to nitrogen compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histamine stimulus. Histamine, the biogenic amine 2-(1H-imidazol-4-yl)ethanamine, is involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter. http://purl.obolibrary.org/obo/GO_0004978 corticotropin receptor activity http://purl.obolibrary.org/obo/GO_0008188 neuropeptide receptor activity Combining with corticotropin to initiate a change in cell activity. http://purl.obolibrary.org/obo/GO_0004990 oxytocin receptor activity http://purl.obolibrary.org/obo/GO_0008528 G protein-coupled peptide receptor activity Combining with oxytocin to initiate a change in cell activity. http://purl.obolibrary.org/obo/GO_0035010 encapsulation of foreign target http://purl.obolibrary.org/obo/GO_0002252 immune effector process Events resulting in the formation of a multilayered cellular sheath surrounding an invader and thus preventing its development. This defense mechanism is often seen in insects in response to nematodes or parasitoids, which are too large to be phagocytosed by individual hemocytes. In some organisms the capsule is blackened due to melanization. http://purl.obolibrary.org/obo/GO_0004994 somatostatin receptor activity http://purl.obolibrary.org/obo/GO_0008188 neuropeptide receptor activity Combining with somatostatin to initiate a change in cell activity. Somatostatin is a peptide hormone that regulates the endocrine system by signaling via G protein-coupled somatostatin receptors. Somatostatin has two active forms produced by proteolytic cleavage: a 14 amino acid peptide (SST-14) and a 28 amino acid peptide (SST-28). http://purl.obolibrary.org/obo/GO_0005000 vasopressin receptor activity http://purl.obolibrary.org/obo/GO_0008528 G protein-coupled peptide receptor activity Combining with vasopressin to initiate a change in cell activity. http://purl.obolibrary.org/obo/GO_0035019 somatic stem cell population maintenance http://purl.obolibrary.org/obo/GO_0019827 stem cell population maintenance Any process by which an organism retains a population of somatic stem cells, undifferentiated cells in the embryo or adult which can undergo unlimited division and give rise to cell types of the body other than those of the germ-line. http://purl.obolibrary.org/obo/GO_0005044 scavenger receptor activity http://purl.obolibrary.org/obo/GO_0038024 cargo receptor activity Combining with any modified low-density lipoprotein (LDL) or other polyanionic ligand and delivering the ligand into the cell via endocytosis. Ligands include acetylated and oxidized LDL, Gram-positive and Gram-negative bacteria, apoptotic cells, amyloid-beta fibrils, and advanced glycation end products (AGEs). http://purl.obolibrary.org/obo/GO_0005122 torso binding http://purl.obolibrary.org/obo/GO_0005102 signaling receptor binding Binding to a torso (tor) protein, a receptor tyrosine kinase. http://purl.obolibrary.org/obo/GO_0035026 leading edge cell differentiation http://purl.obolibrary.org/obo/GO_0030855 epithelial cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features of leading edge cells, cells at the front of a migrating epithelial sheet. http://purl.obolibrary.org/obo/GO_0005172 vascular endothelial growth factor receptor binding http://purl.obolibrary.org/obo/GO_0005126 cytokine receptor binding Binding to a vascular endothelial growth factor receptor. http://purl.obolibrary.org/obo/GO_0005173 stem cell factor receptor binding http://purl.obolibrary.org/obo/GO_0005126 cytokine receptor binding Binding to a stem cell factor receptor (SCFR), a type III transmembrane kinase receptor. http://purl.obolibrary.org/obo/GO_0035039 male pronucleus assembly http://purl.obolibrary.org/obo/GO_0070925 organelle assembly The conversion at fertilization of the inactive sperm nucleus into a male pronucleus with its chromosomes processed for the first zygotic division. http://purl.obolibrary.org/obo/GO_0005215 transporter activity http://purl.obolibrary.org/obo/GO_0003674 molecular_function Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, accross or in between cells. http://purl.obolibrary.org/obo/GO_0005216 monoatomic ion channel activity http://purl.obolibrary.org/obo/GO_0015267 channel activity Enables the facilitated diffusion of a monoatomic ion (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. May be either selective (it enables passage of a specific ion only) or non-selective (it enables passage of two or more ions of same charge but different size). http://purl.obolibrary.org/obo/GO_0035040 sperm nuclear envelope removal http://purl.obolibrary.org/obo/GO_0051081 nuclear membrane disassembly Removal of the sperm nuclear envelope, allowing entry of maternal factors into the sperm nucleus. http://purl.obolibrary.org/obo/GO_0005227 calcium-activated cation channel activity http://purl.obolibrary.org/obo/GO_0099094 ligand-gated monoatomic cation channel activity Enables the transmembrane transfer of an inorganic cation by a channel that opens when a calcium cation has been bound by the channel complex or one of its constituent parts. http://purl.obolibrary.org/obo/GO_0005228 intracellular sodium-activated potassium channel activity http://purl.obolibrary.org/obo/GO_0099094 ligand-gated monoatomic cation channel activity Enables the transmembrane transfer of potassium by a channel that opens in response to stimulus by a sodium ion or ions. Transport by a channel involves facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism. Sodium activated potassium channels have distinctive properties, including a large single channel conductance, subconductance states, and a block of single channel currents at positive potentials, similar to inward rectification. http://purl.obolibrary.org/obo/GO_0035045 sperm plasma membrane disassembly http://purl.obolibrary.org/obo/GO_0030397 membrane disassembly The gradual disintegration of the sperm plasma membrane following insemination. This process is seen in Drosophila after entry of the entire sperm, surrounded by its plasma membrane, into the egg. http://purl.obolibrary.org/obo/GO_0005230 extracellular ligand-gated monoatomic ion channel activity http://purl.obolibrary.org/obo/GO_0015276 ligand-gated monoatomic ion channel activity Enables the transmembrane transfer of an ion by a channel that opens when a specific extracellular ligand has been bound by the channel complex or one of its constituent parts. http://purl.obolibrary.org/obo/GO_0005231 excitatory extracellular ligand-gated monoatomic ion channel activity http://purl.obolibrary.org/obo/GO_0005230 extracellular ligand-gated monoatomic ion channel activity Enables the transmembrane transfer of an ion by a channel that opens when a specific extracellular ligand has been bound by the channel complex or one of its constituent parts, where channel opening contributes to an increase in membrane potential. http://purl.obolibrary.org/obo/GO_0035099 hemocyte migration http://purl.obolibrary.org/obo/GO_0016477 cell migration The directed movement of a hemocyte within the embryo. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. In Drosophila, embryonic hemocytes originate from the head mesoderm as a cluster of cells. The cluster splits into two and one group of cells crosses the amnioserosa. Both populations then spread toward the middle of the embryo and then disperse evenly throughout the embryo. http://purl.obolibrary.org/obo/GO_0005244 voltage-gated monoatomic ion channel activity http://purl.obolibrary.org/obo/GO_0022832 voltage-gated channel activity Enables the transmembrane transfer of an ion by a voltage-gated channel. An ion is an atom or group of atoms carrying an electric charge by virtue of having gained or lost one or more electrons. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. http://purl.obolibrary.org/obo/GO_0005245 voltage-gated calcium channel activity http://purl.obolibrary.org/obo/GO_0022843 voltage-gated monoatomic cation channel activity Enables the transmembrane transfer of a calcium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. http://purl.obolibrary.org/obo/GO_0035136 forelimb morphogenesis http://purl.obolibrary.org/obo/GO_0035108 limb morphogenesis The process in which the anatomical structures of the forelimb are generated and organized. The forelimbs are the front limbs of an animal, e.g. the arms of a human. http://purl.obolibrary.org/obo/GO_0005248 voltage-gated sodium channel activity http://purl.obolibrary.org/obo/GO_0005272 sodium channel activity Enables the transmembrane transfer of a sodium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. http://purl.obolibrary.org/obo/GO_0005249 voltage-gated potassium channel activity http://purl.obolibrary.org/obo/GO_0022843 voltage-gated monoatomic cation channel activity Enables the transmembrane transfer of a potassium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. http://purl.obolibrary.org/obo/GO_0035137 hindlimb morphogenesis http://purl.obolibrary.org/obo/GO_0035108 limb morphogenesis The process in which the anatomical structures of the hindlimb are generated and organized. http://purl.obolibrary.org/obo/GO_0005261 monoatomic cation channel activity http://purl.obolibrary.org/obo/GO_0008324 monoatomic cation transmembrane transporter activity Enables the energy-independent facilitated diffusion of a monoatomic cation through a transmembrane aqueous pore or channel. http://purl.obolibrary.org/obo/GO_0005262 calcium channel activity http://purl.obolibrary.org/obo/GO_0015085 calcium ion transmembrane transporter activity Enables the energy-independent facilitated diffusion of a calcium ion through a transmembrane aqueous pore or channel. http://purl.obolibrary.org/obo/GO_0035148 tube formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis Creation of the central hole of a tube in an anatomical structure through which gases and/or liquids flow. http://purl.obolibrary.org/obo/GO_0005267 potassium channel activity http://purl.obolibrary.org/obo/GO_0015079 potassium ion transmembrane transporter activity Enables the energy-independent facilitated diffusion of a potassium ion through a transmembrane aqueous pore or channel. http://purl.obolibrary.org/obo/GO_0005272 sodium channel activity http://purl.obolibrary.org/obo/GO_0015081 sodium ion transmembrane transporter activity Enables the energy-independent facilitated diffusion of a sodium ion through a transmembrane aqueous pore or channel. http://purl.obolibrary.org/obo/GO_0005275 amine transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity Enables the transfer of amines, including polyamines, from one side of a membrane to the other. Amines are organic compounds that are weakly basic in character and contain an amino (-NH2) or substituted amino group. http://purl.obolibrary.org/obo/GO_0035162 embryonic hemopoiesis http://purl.obolibrary.org/obo/GO_0048568 embryonic organ development The stages of blood cell formation that take place within the embryo. http://purl.obolibrary.org/obo/GO_0005277 acetylcholine transmembrane transporter activity http://purl.obolibrary.org/obo/GO_1901375 acetate ester transmembrane transporter activity Enables the transfer of acetylcholine from one side of a membrane to the other. Acetylcholine is an acetic acid ester of the organic base choline and functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions. http://purl.obolibrary.org/obo/GO_0005290 L-histidine transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0015179 L-amino acid transmembrane transporter activity Enables the transfer of L-histidine from one side of a membrane to the other. L-histidine is 2-amino-3-(1H-imidazol-4-yl)propanoic acid. http://purl.obolibrary.org/obo/GO_0035163 embryonic hemocyte differentiation http://purl.obolibrary.org/obo/GO_0042386 hemocyte differentiation The process in which a relatively unspecialized cell derived from the embryonic head mesoderm acquires the specialized features of a mature hemocyte. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. http://purl.obolibrary.org/obo/GO_0005313 L-glutamate transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0015179 L-amino acid transmembrane transporter activity Enables the transfer of L-glutamate from one side of a membrane to the other. L-glutamate is the anion of 2-aminopentanedioic acid. http://purl.obolibrary.org/obo/GO_0005315 phosphate transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0015291 secondary active transmembrane transporter activity Enables the transfer of phosphate ions from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters. http://purl.obolibrary.org/obo/GO_0005319 lipid transporter activity http://purl.obolibrary.org/obo/GO_0005215 transporter activity Enables the directed movement of lipids into, out of or within a cell, or between cells. http://purl.obolibrary.org/obo/GO_0035165 embryonic crystal cell differentiation http://purl.obolibrary.org/obo/GO_0042688 crystal cell differentiation The process in which an embryonic mesoderm-derived hemocyte precursor cell acquires the specialized features of a crystal cell. Crystal cells are a class of cells that contain crystalline inclusions and are involved in the melanization of pathogenic material in the hemolymph. http://purl.obolibrary.org/obo/GO_0005326 neurotransmitter transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity Enables the directed movement of a neurotransmitter into, out of or within a cell, or between cells. Neurotransmitters are any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell. http://purl.obolibrary.org/obo/GO_0005346 purine ribonucleotide transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0015216 purine nucleotide transmembrane transporter activity Enables the transfer of a purine ribonucleotide, any compound consisting of a purine ribonucleoside (a purine organic base attached to a ribose sugar) esterified with (ortho)phosphate, from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0005347 ATP transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0000295 adenine nucleotide transmembrane transporter activity Enables the transfer of ATP, adenosine triphosphate, from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0035166 post-embryonic hemopoiesis http://purl.obolibrary.org/obo/GO_0030097 hemopoiesis The stages of blood cell formation that take place after completion of embryonic development. http://purl.obolibrary.org/obo/GO_0005372 water transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity Enables the transfer of water (H2O) from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0005381 iron ion transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0046915 transition metal ion transmembrane transporter activity Enables the transfer of iron (Fe) ions from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0035167 larval lymph gland hemopoiesis http://purl.obolibrary.org/obo/GO_0035166 post-embryonic hemopoiesis The production of blood cells from the larval lymph gland. The lymph gland consists of three to six bilaterally paired lobes that are attached to the cardioblasts during larval stages, and it degenerates during pupal stages. http://purl.obolibrary.org/obo/GO_0005496 steroid binding http://purl.obolibrary.org/obo/GO_0008289 lipid binding Binding to a steroid, any of a large group of substances that have in common a ring system based on 1,2-cyclopentanoperhydrophenanthrene. http://purl.obolibrary.org/obo/GO_0005500 juvenile hormone binding http://purl.obolibrary.org/obo/GO_0042562 hormone binding Binding to a juvenile hormone, a sesquiterpenoid derivative that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis. http://purl.obolibrary.org/obo/GO_0035168 larval lymph gland hemocyte differentiation http://purl.obolibrary.org/obo/GO_0042386 hemocyte differentiation The process in which a relatively unspecialized cell derived from the larval lymph gland acquires the specialized features of a mature hemocyte. The lymph gland consists of three to six bilaterally paired lobes that are attached to the cardioblasts during larval stages, and it degenerates during pupal stages. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this process is found in Drosophila melanogaster. http://purl.obolibrary.org/obo/GO_0005504 fatty acid binding http://purl.obolibrary.org/obo/GO_0033293 monocarboxylic acid binding Binding to a fatty acid, an aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis. http://purl.obolibrary.org/obo/GO_0005506 iron ion binding http://purl.obolibrary.org/obo/GO_0046914 transition metal ion binding Binding to an iron (Fe) ion. http://purl.obolibrary.org/obo/GO_0005509 calcium ion binding http://purl.obolibrary.org/obo/GO_0046872 metal ion binding Binding to a calcium ion (Ca2+). http://purl.obolibrary.org/obo/GO_0035169 lymph gland plasmatocyte differentiation http://purl.obolibrary.org/obo/GO_0042387 plasmatocyte differentiation The process in which a relatively unspecialized larval lymph gland-derived hemocyte precursor cell acquires the specialized features of the phagocytic blood-cell type, the plasmatocyte. http://purl.obolibrary.org/obo/GO_0005518 collagen binding http://purl.obolibrary.org/obo/GO_0044877 protein-containing complex binding Binding to collagen, a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%). http://purl.obolibrary.org/obo/GO_0035170 lymph gland crystal cell differentiation http://purl.obolibrary.org/obo/GO_0042688 crystal cell differentiation The process in which a relatively unspecialized larval lymph gland-derived hemocyte precursor cell acquires the specialized features of a crystal cell. Crystal cells are a class of cells that contain crystalline inclusions and are involved in the melanization of pathogenic material in the hemolymph. http://purl.obolibrary.org/obo/GO_0005524 ATP binding http://purl.obolibrary.org/obo/GO_0035639 purine ribonucleoside triphosphate binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. http://purl.obolibrary.org/obo/GO_0005536 D-glucose binding http://purl.obolibrary.org/obo/GO_0048029 monosaccharide binding Binding to D-enantiomers of glucose. http://purl.obolibrary.org/obo/GO_0035171 lamellocyte differentiation http://purl.obolibrary.org/obo/GO_0035168 larval lymph gland hemocyte differentiation The process in which a relatively unspecialized hemocyte precursor cell acquires the specialized features of a lamellocyte. Lamellocytes are a hemocyte lineage that exists only in larvae, but are seldom observed in healthy animals. Lamellocytes differentiate massively in the lymph glands after parasitization and are large flat cells devoted to encapsulation of invaders too large to be phagocytosed by plasmatocytes. http://purl.obolibrary.org/obo/GO_0005539 glycosaminoglycan binding http://purl.obolibrary.org/obo/GO_0097367 carbohydrate derivative binding Binding to a glycan (polysaccharide) containing a substantial proportion of aminomonosaccharide residues. http://purl.obolibrary.org/obo/GO_0035172 hemocyte proliferation http://purl.obolibrary.org/obo/GO_0008283 cell population proliferation The multiplication or reproduction of hemocytes, resulting in the expansion of the cell population. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. http://purl.obolibrary.org/obo/GO_0005540 hyaluronic acid binding http://purl.obolibrary.org/obo/GO_0005539 glycosaminoglycan binding Binding to hyaluronic acid, a polymer composed of repeating dimeric units of glucuronic acid and N-acetyl glucosamine. http://purl.obolibrary.org/obo/GO_0035190 syncytial nuclear migration http://purl.obolibrary.org/obo/GO_0007097 nuclear migration The directed movement of nuclei within the syncytial embryo of insects. These precise temporal and spatial patterns of nuclear movement are coordinated with mitotic divisions and are required during blastoderm formation to reposition dividing nuclei from the interior of the syncytial embryo to the cortex. http://purl.obolibrary.org/obo/GO_0005576 extracellular region http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite. http://purl.obolibrary.org/obo/GO_0035203 regulation of lamellocyte differentiation http://purl.obolibrary.org/obo/GO_1903706 regulation of hemopoiesis Any process that modulates the frequency, rate or extent of lamellocyte differentiation. Lamellocytes differentiate massively in the lymph glands after parasitization and are large flat cells devoted to encapsulation of invaders too large to be phagocytosed by plasmatocytes. http://purl.obolibrary.org/obo/GO_0005577 fibrinogen complex http://purl.obolibrary.org/obo/GO_0032991 protein-containing complex A highly soluble, elongated protein complex found in blood plasma and involved in clot formation. It is converted into fibrin monomer by the action of thrombin. In the mouse, fibrinogen is a hexamer, 46 nm long and 9 nm maximal diameter, containing two sets of nonidentical chains (alpha, beta, and gamma) linked together by disulfide bonds. http://purl.obolibrary.org/obo/GO_0005581 collagen trimer http://purl.obolibrary.org/obo/GO_0032991 protein-containing complex A protein complex consisting of three collagen chains assembled into a left-handed triple helix. These trimers typically assemble into higher order structures. http://purl.obolibrary.org/obo/GO_0035204 negative regulation of lamellocyte differentiation http://purl.obolibrary.org/obo/GO_0045611 negative regulation of hemocyte differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of lamellocyte differentiation. Lamellocytes differentiate massively in the lymph glands after parasitization and are large flat cells devoted to encapsulation of invaders too large to be phagocytosed by plasmatocytes. http://purl.obolibrary.org/obo/GO_0005583 fibrillar collagen trimer http://purl.obolibrary.org/obo/GO_0005581 collagen trimer Any triple helical collagen trimer that forms fibrils. http://purl.obolibrary.org/obo/GO_0035205 positive regulation of lamellocyte differentiation http://purl.obolibrary.org/obo/GO_0045612 positive regulation of hemocyte differentiation Any process that activates or increases the frequency, rate or extent of lamellocyte differentiation. Lamellocytes differentiate massively in the lymph glands after parasitization and are large flat cells devoted to encapsulation of invaders too large to be phagocytosed by plasmatocytes. http://purl.obolibrary.org/obo/GO_0005584 collagen type I trimer http://purl.obolibrary.org/obo/GO_0005583 fibrillar collagen trimer A collagen trimer containing alpha(I) chains. The most common form of type I collagen is a heterotrimer containing two alpha1(I) chains and one alpha2(I) chain; homotrimers containing three alpha1(I) chains are also found. Type I collagen triple helices associate to form banded fibrils. http://purl.obolibrary.org/obo/GO_0005585 collagen type II trimer http://purl.obolibrary.org/obo/GO_0005583 fibrillar collagen trimer A collagen homotrimer of alpha1(II) chains; type II collagen triple helices associate to form fibrils. http://purl.obolibrary.org/obo/GO_0035206 regulation of hemocyte proliferation http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of hemocyte proliferation. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this is found in Drosophila melanogaster. http://purl.obolibrary.org/obo/GO_0005587 collagen type IV trimer http://purl.obolibrary.org/obo/GO_0098642 network-forming collagen trimer A collagen heterotrimer containing type IV alpha chains; [alpha1(IV)]2alpha2(IV) trimers are commonly observed, although more type IV alpha chains exist and may be present in type IV trimers; type IV collagen triple helices associate to form 3 dimensional nets within basement membranes. http://purl.obolibrary.org/obo/GO_0035207 negative regulation of hemocyte proliferation http://purl.obolibrary.org/obo/GO_0008285 negative regulation of cell population proliferation Any process that stops, prevents or reduces the rate or extent of hemocyte proliferation. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this is found in Drosophila melanogaster. http://purl.obolibrary.org/obo/GO_0005604 basement membrane http://purl.obolibrary.org/obo/GO_0031012 extracellular matrix A collagen-containing extracellular matrix consisting of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue. It consists of the basal lamina plus an associated layer of reticulin fibers. http://purl.obolibrary.org/obo/GO_0035208 positive regulation of hemocyte proliferation http://purl.obolibrary.org/obo/GO_0035206 regulation of hemocyte proliferation Any process that activates or increases the rate or extent of hemocyte proliferation. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) that are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this process is found in Drosophila melanogaster. http://purl.obolibrary.org/obo/GO_0005614 interstitial matrix http://purl.obolibrary.org/obo/GO_0031012 extracellular matrix A type of extracellular matrix found in interstitial connective tissue, characterized by the presence of fibronectins, proteoglycans, and types I, III, V, VI, VII and XII collagens. http://purl.obolibrary.org/obo/GO_0005615 extracellular space http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid. http://purl.obolibrary.org/obo/GO_0035234 ectopic germ cell programmed cell death http://purl.obolibrary.org/obo/GO_0010623 programmed cell death involved in cell development Programmed cell death of an errant germ line cell that is outside the normal migratory path or ectopic to the gonad. This is an important mechanism of regulating germ cell survival within the embryo. http://purl.obolibrary.org/obo/GO_0005635 nuclear envelope http://purl.obolibrary.org/obo/GO_0031967 organelle envelope The double lipid bilayer that encloses the nucleus, separating its contents from the cytoplasm. It consists of an inner and outer nuclear membrane, with an intermembrane space (20-40 nm wide, also called the perinuclear space) between them. The envelope is supported by the nuclear lamina and contains nuclear pore complexes, which regulate molecular transport. http://purl.obolibrary.org/obo/GO_0035249 synaptic transmission, glutamatergic http://purl.obolibrary.org/obo/GO_0007268 chemical synaptic transmission The vesicular release of glutamate from a presynapse, across a chemical synapse, the subsequent activation of glutamate receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse. http://purl.obolibrary.org/obo/GO_0005640 nuclear outer membrane http://purl.obolibrary.org/obo/GO_0031968 organelle outer membrane The outer, i.e. cytoplasm-facing, lipid bilayer of the nuclear envelope; continuous with the endoplasmic reticulum of the cell and sometimes studded with ribosomes. http://purl.obolibrary.org/obo/GO_0005677 chromatin silencing complex http://purl.obolibrary.org/obo/GO_0140513 nuclear protein-containing complex Any protein complex that mediates changes in chromatin structure that result in transcriptional silencing. http://purl.obolibrary.org/obo/GO_0035260 internal genitalia morphogenesis http://purl.obolibrary.org/obo/GO_0035112 genitalia morphogenesis The process in which the anatomical structures of the internal genitalia are generated and organized. The internal genitalia are the internal sex organs such as the uterine tube, the uterus and the vagina in female mammals, and the testis, seminal vesicle, ejaculatory duct and prostate in male mammals. http://purl.obolibrary.org/obo/GO_0005730 nucleolus http://purl.obolibrary.org/obo/GO_0043232 intracellular membraneless organelle A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome. http://purl.obolibrary.org/obo/GO_0035261 external genitalia morphogenesis http://purl.obolibrary.org/obo/GO_0035112 genitalia morphogenesis The process in which the anatomical structures of the external genitalia are generated and organized. The external genitalia are the outer sex organs, such as the penis or vulva in mammals. http://purl.obolibrary.org/obo/GO_0035262 gonad morphogenesis http://purl.obolibrary.org/obo/GO_0009887 animal organ morphogenesis The process in which the anatomical structures of the gonads are generated and organized. A gonad is an animal organ producing gametes, e.g. the testes or the ovary in mammals. http://purl.obolibrary.org/obo/GO_0005740 mitochondrial envelope http://purl.obolibrary.org/obo/GO_0031967 organelle envelope The double lipid bilayer enclosing the mitochondrion and separating its contents from the cell cytoplasm; includes the intermembrane space. http://purl.obolibrary.org/obo/GO_0035264 multicellular organism growth http://purl.obolibrary.org/obo/GO_0048589 developmental growth The increase in size or mass of an entire multicellular organism, as opposed to cell growth. http://purl.obolibrary.org/obo/GO_0005759 mitochondrial matrix http://purl.obolibrary.org/obo/GO_0070013 intracellular organelle lumen The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation. http://purl.obolibrary.org/obo/GO_0035290 trunk segmentation http://purl.obolibrary.org/obo/GO_0035282 segmentation Partitioning of the blastoderm embryo into trunk segmental units. In Drosophila, the trunk segments include thoracic segments and abdominal segments A1 to A8. http://purl.obolibrary.org/obo/GO_0035315 hair cell differentiation http://purl.obolibrary.org/obo/GO_0030182 neuron differentiation The process in which a relatively unspecialized cell acquires specialized features of a hair cell. http://purl.obolibrary.org/obo/GO_0005761 mitochondrial ribosome http://purl.obolibrary.org/obo/GO_0000313 organellar ribosome A ribosome found in the mitochondrion of a eukaryotic cell; contains a characteristic set of proteins distinct from those of cytosolic ribosomes. http://purl.obolibrary.org/obo/GO_0035316 non-sensory hair organization http://purl.obolibrary.org/obo/GO_0120036 plasma membrane bounded cell projection organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of non-sensory hairs. These hairs are polarized cellular extensions that cover much of the insect epidermis. http://purl.obolibrary.org/obo/GO_0005765 lysosomal membrane http://purl.obolibrary.org/obo/GO_0098852 lytic vacuole membrane The lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm. http://purl.obolibrary.org/obo/GO_0035369 pre-B cell receptor complex http://purl.obolibrary.org/obo/GO_0098796 membrane protein complex An immunoglobulin-like complex that is present in at least the plasma membrane of pre-B cells, and that is composed of two identical immunoglobulin heavy chains and two surrogate light chains, each composed of the lambda-5 and VpreB proteins, and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins. http://purl.obolibrary.org/obo/GO_0005766 primary lysosome http://purl.obolibrary.org/obo/GO_0005764 lysosome A lysosome before it has fused with a vesicle or vacuole. http://purl.obolibrary.org/obo/GO_0005794 Golgi apparatus http://purl.obolibrary.org/obo/GO_0043231 intracellular membrane-bounded organelle A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways. http://purl.obolibrary.org/obo/GO_0035372 protein localization to microtubule http://purl.obolibrary.org/obo/GO_0072698 protein localization to microtubule cytoskeleton A process in which a protein is transported to, or maintained at, a microtubule. http://purl.obolibrary.org/obo/GO_0035374 chondroitin sulfate binding http://purl.obolibrary.org/obo/GO_1901681 sulfur compound binding Binding to chondroitin sulfate, a glycosaminoglycan made up of two alternating monosaccharides: D-glucuronic acid (GlcA) and N-acetyl-D-galactosamine (GalNAc). http://purl.obolibrary.org/obo/GO_0005798 Golgi-associated vesicle http://purl.obolibrary.org/obo/GO_0031410 cytoplasmic vesicle Any vesicle associated with the Golgi complex and involved in mediating transport within the Golgi or between the Golgi and other parts of the cell. http://purl.obolibrary.org/obo/GO_0035377 transepithelial water transport http://purl.obolibrary.org/obo/GO_0042045 epithelial fluid transport The directed movement of water (H2O) from one side of an epithelium to the other. http://purl.obolibrary.org/obo/GO_0005814 centriole http://purl.obolibrary.org/obo/GO_0043232 intracellular membraneless organelle A cellular organelle, found close to the nucleus in many eukaryotic cells, consisting of a small cylinder with microtubular walls, 300-500 nm long and 150-250 nm in diameter. It contains nine short, parallel, peripheral microtubular fibrils, each fibril consisting of one complete microtubule fused to two incomplete microtubules. Cells usually have two centrioles, lying at right angles to each other. At division, each pair of centrioles generates another pair and the twin pairs form the pole of the mitotic spindle. http://purl.obolibrary.org/obo/GO_0035418 protein localization to synapse http://purl.obolibrary.org/obo/GO_1902414 protein localization to cell junction Any process in which a protein is transported to, and/or maintained at the synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell. http://purl.obolibrary.org/obo/GO_0035441 cell migration involved in vasculogenesis http://purl.obolibrary.org/obo/GO_0016477 cell migration The orderly movement of a cell from one site to another that will contribute to the differentiation of an endothelial cell that will form de novo blood vessels and tubes. http://purl.obolibrary.org/obo/GO_0005856 cytoskeleton http://purl.obolibrary.org/obo/GO_0043232 intracellular membraneless organelle A cellular structure that forms the internal framework of eukaryotic and prokaryotic cells. The cytoskeleton includes intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles. http://purl.obolibrary.org/obo/GO_0035490 regulation of leukotriene production involved in inflammatory response http://purl.obolibrary.org/obo/GO_0051239 regulation of multicellular organismal process Any process that modulates the rate, frequency or extent of the synthesis or release of any leukotriene following a stimulus as part of an inflammatory response. http://purl.obolibrary.org/obo/GO_0035491 positive regulation of leukotriene production involved in inflammatory response http://purl.obolibrary.org/obo/GO_0035490 regulation of leukotriene production involved in inflammatory response Any process that increases the rate, frequency or extent of the synthesis or release of any leukotriene following a stimulus as part of an inflammatory response. http://purl.obolibrary.org/obo/GO_0005858 axonemal dynein complex http://purl.obolibrary.org/obo/GO_0030286 dynein complex A dynein complex found in eukaryotic cilia and flagella; the motor domain heads interact with adjacent microtubules to generate a sliding force which is converted to a bending motion. http://purl.obolibrary.org/obo/GO_0035493 SNARE complex assembly http://purl.obolibrary.org/obo/GO_0065003 protein-containing complex assembly The aggregation, arrangement and bonding together of a set of components to form a SNARE complex, a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers. http://purl.obolibrary.org/obo/GO_0005874 microtubule http://purl.obolibrary.org/obo/GO_0099513 polymeric cytoskeletal fiber Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle. http://purl.obolibrary.org/obo/GO_0035494 SNARE complex disassembly http://purl.obolibrary.org/obo/GO_0032984 protein-containing complex disassembly The disaggregation of the SNARE protein complex into its constituent components. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers. http://purl.obolibrary.org/obo/GO_0005875 microtubule associated complex http://purl.obolibrary.org/obo/GO_0032991 protein-containing complex Any multimeric complex connected to a microtubule. http://purl.obolibrary.org/obo/GO_0035495 regulation of SNARE complex disassembly http://purl.obolibrary.org/obo/GO_0043244 regulation of protein-containing complex disassembly Any process that modulates the frequency, rate or extent of disassembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers. http://purl.obolibrary.org/obo/GO_0005879 axonemal microtubule http://purl.obolibrary.org/obo/GO_0005881 cytoplasmic microtubule A microtubule in the axoneme of a eukaryotic cilium or flagellum; an axoneme contains nine modified doublet microtubules, which may or may not surround a pair of single microtubules. http://purl.obolibrary.org/obo/GO_0035540 positive regulation of SNARE complex disassembly http://purl.obolibrary.org/obo/GO_0051050 positive regulation of transport Any process that increases the frequency, rate or extent of disassembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers. http://purl.obolibrary.org/obo/GO_0005880 nuclear microtubule http://purl.obolibrary.org/obo/GO_0005874 microtubule Any microtubule in the nucleus of a cell. http://purl.obolibrary.org/obo/GO_0005882 intermediate filament http://purl.obolibrary.org/obo/GO_0099513 polymeric cytoskeletal fiber A cytoskeletal structure that forms a distinct elongated structure, characteristically 10 nm in diameter, that occurs in the cytoplasm of eukaryotic cells. Intermediate filaments form a fibrous system, composed of chemically heterogeneous subunits and involved in mechanically integrating the various components of the cytoplasmic space. Intermediate filaments may be divided into five chemically distinct classes: Type I, acidic keratins; Type II, basic keratins; Type III, including desmin, vimentin and others; Type IV, neurofilaments and related filaments; and Type V, lamins. http://purl.obolibrary.org/obo/GO_0035541 negative regulation of SNARE complex disassembly http://purl.obolibrary.org/obo/GO_0051051 negative regulation of transport Any process that decreases the frequency, rate or extent of disassembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers. http://purl.obolibrary.org/obo/GO_0035542 regulation of SNARE complex assembly http://purl.obolibrary.org/obo/GO_0043254 regulation of protein-containing complex assembly Any process that modulates the frequency, rate or extent of assembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers. http://purl.obolibrary.org/obo/GO_0005884 actin filament http://purl.obolibrary.org/obo/GO_0099513 polymeric cytoskeletal fiber A filamentous structure formed of a two-stranded helical polymer of the protein actin and associated proteins. Actin filaments are a major component of the contractile apparatus of skeletal muscle and the microfilaments of the cytoskeleton of eukaryotic cells. The filaments, comprising polymerized globular actin molecules, appear as flexible structures with a diameter of 5-9 nm. They are organized into a variety of linear bundles, two-dimensional networks, and three dimensional gels. In the cytoskeleton they are most highly concentrated in the cortex of the cell just beneath the plasma membrane. http://purl.obolibrary.org/obo/GO_0035543 positive regulation of SNARE complex assembly http://purl.obolibrary.org/obo/GO_0035542 regulation of SNARE complex assembly Any process that increases the frequency, rate or extent of assembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers. http://purl.obolibrary.org/obo/GO_0035544 negative regulation of SNARE complex assembly http://purl.obolibrary.org/obo/GO_0035542 regulation of SNARE complex assembly Any process that decreases the frequency, rate or extent of assembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers. http://purl.obolibrary.org/obo/GO_0005891 voltage-gated calcium channel complex http://purl.obolibrary.org/obo/GO_0098797 plasma membrane protein complex A protein complex that forms a transmembrane channel through which calcium ions may pass in response to changes in membrane potential. http://purl.obolibrary.org/obo/GO_0005902 microvillus http://purl.obolibrary.org/obo/GO_0098858 actin-based cell projection Thin cylindrical membrane-covered projections on the surface of an animal cell containing a core bundle of actin filaments. Present in especially large numbers on the absorptive surface of intestinal cells. http://purl.obolibrary.org/obo/GO_0035562 negative regulation of chromatin binding http://purl.obolibrary.org/obo/GO_0051100 negative regulation of binding Any process that stops or reduces the frequency, rate or extent of chromatin binding. Chromatin binding is the selective interaction with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase. http://purl.obolibrary.org/obo/GO_0005903 brush border http://purl.obolibrary.org/obo/GO_0098862 cluster of actin-based cell projections The dense covering of microvilli on the apical surface of an epithelial cell in tissues such as the intestine, kidney, and choroid plexus; the microvilli aid absorption by increasing the surface area of the cell. http://purl.obolibrary.org/obo/GO_0035563 positive regulation of chromatin binding http://purl.obolibrary.org/obo/GO_0051099 positive regulation of binding Any process that increases the frequency, rate or extent of chromatin binding. Chromatin binding is the selective interaction with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase. http://purl.obolibrary.org/obo/GO_0005911 cell-cell junction http://purl.obolibrary.org/obo/GO_0070161 anchoring junction A cell junction that forms a connection between two or more cells of an organism; excludes direct cytoplasmic intercellular bridges, such as ring canals in insects. http://purl.obolibrary.org/obo/GO_0035577 azurophil granule membrane http://purl.obolibrary.org/obo/GO_0030667 secretory granule membrane The lipid bilayer surrounding an azurophil granule, a primary lysosomal granule found in neutrophil granulocytes that contains a wide range of hydrolytic enzymes and is released into the extracellular fluid. http://purl.obolibrary.org/obo/GO_0005923 bicellular tight junction http://purl.obolibrary.org/obo/GO_0070160 tight junction An occluding cell-cell junction that is composed of a branching network of sealing strands that completely encircles the apical end of each cell in an epithelial sheet; the outer leaflets of the two interacting plasma membranes are seen to be tightly apposed where sealing strands are present. Each sealing strand is composed of a long row of transmembrane adhesion proteins embedded in each of the two interacting plasma membranes. http://purl.obolibrary.org/obo/GO_0035589 G protein-coupled purinergic nucleotide receptor signaling pathway http://purl.obolibrary.org/obo/GO_0035590 purinergic nucleotide receptor signaling pathway A G protein-coupled receptor signaling pathway initiated by an extracellular purine nucleotide binding to its receptor, and ending with the regulation of a downstream cellular process. http://purl.obolibrary.org/obo/GO_0035592 establishment of protein localization to extracellular region http://purl.obolibrary.org/obo/GO_0045184 establishment of protein localization The directed movement of a protein to a specific location within the extracellular region. http://purl.obolibrary.org/obo/GO_0005927 muscle tendon junction http://purl.obolibrary.org/obo/GO_0030055 cell-substrate junction A cell-substrate junction found at the terminal anchorage site of skeletal muscle cells to tendons. http://purl.obolibrary.org/obo/GO_0005929 cilium http://purl.obolibrary.org/obo/GO_0043227 membrane-bounded organelle A specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface and of some cytoplasmic parts. Each cilium is largely bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored to a basal body. http://purl.obolibrary.org/obo/GO_0035622 intrahepatic bile duct development http://purl.obolibrary.org/obo/GO_0061009 common bile duct development The progression of the intrahepatic bile ducts over time, from their formation to the mature structure. Intrahepatic bile ducts (bile ducts within the liver) collect bile from bile canaliculi in the liver, and connect to the extrahepatic bile ducts (bile ducts outside the liver). http://purl.obolibrary.org/obo/GO_0005930 axoneme http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure The bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements. http://purl.obolibrary.org/obo/GO_0035628 cystic duct development http://purl.obolibrary.org/obo/GO_0061009 common bile duct development The progression of the cystic duct over time, from its formation to the mature structure. The cystic duct runs from the gallbladder to the common bile duct. http://purl.obolibrary.org/obo/GO_0005938 cell cortex http://purl.obolibrary.org/obo/GO_0005737 cytoplasm The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins. http://purl.obolibrary.org/obo/GO_0035630 bone mineralization involved in bone maturation http://purl.obolibrary.org/obo/GO_0030282 bone mineralization The deposition of hydroxyapatite, involved in the progression of the skeleton from its formation to its mature state. http://purl.obolibrary.org/obo/GO_0005975 carbohydrate metabolic process http://purl.obolibrary.org/obo/GO_0044238 primary metabolic process The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. http://purl.obolibrary.org/obo/GO_0035645 enteric smooth muscle cell differentiation http://purl.obolibrary.org/obo/GO_0051145 smooth muscle cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell of the intestine. http://purl.obolibrary.org/obo/GO_0005978 glycogen biosynthetic process http://purl.obolibrary.org/obo/GO_0005977 glycogen metabolic process The chemical reactions and pathways resulting in the formation of glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues. http://purl.obolibrary.org/obo/GO_0035675 neuromast hair cell development http://purl.obolibrary.org/obo/GO_0048666 neuron development The process whose specific outcome is the progression of a neuromast hair cell over time, from its formation to the mature structure. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. Cell development does not include the steps involved in committing a cell to a specific fate. http://purl.obolibrary.org/obo/GO_0005979 regulation of glycogen biosynthetic process http://purl.obolibrary.org/obo/GO_0070873 regulation of glycogen metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen. http://purl.obolibrary.org/obo/GO_0035676 anterior lateral line neuromast hair cell development http://purl.obolibrary.org/obo/GO_0035675 neuromast hair cell development The process whose specific outcome is the progression of an anterior lateral line neuromast hair cell over time, from its formation to the mature structure. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. Cell development does not include the steps involved in committing a cell to a specific fate. http://purl.obolibrary.org/obo/GO_0005980 glycogen catabolic process http://purl.obolibrary.org/obo/GO_0005977 glycogen metabolic process The chemical reactions and pathways resulting in the breakdown of glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues. http://purl.obolibrary.org/obo/GO_0005981 regulation of glycogen catabolic process http://purl.obolibrary.org/obo/GO_0070873 regulation of glycogen metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen. http://purl.obolibrary.org/obo/GO_0035677 posterior lateral line neuromast hair cell development http://purl.obolibrary.org/obo/GO_0035675 neuromast hair cell development The process whose specific outcome is the progression of a posterior lateral line neuromast hair cell over time, from its formation to the mature structure. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. Cell development does not include the steps involved in committing a cell to a specific fate. http://purl.obolibrary.org/obo/GO_0005982 starch metabolic process http://purl.obolibrary.org/obo/GO_0044042 glucan metabolic process The chemical reactions and pathways involving starch, the most important reserve polysaccharide in plants. It is a glucan consisting of two components, amylose and amylopectin, which are both glucose homopolymers. Starch is synthesized as a temporary storage form of carbon and can be catabolized to produce sucrose. http://purl.obolibrary.org/obo/GO_0005983 starch catabolic process http://purl.obolibrary.org/obo/GO_0009251 glucan catabolic process The chemical reactions and pathways resulting in the breakdown of starch, the most important reserve polysaccharide in plants. http://purl.obolibrary.org/obo/GO_0035678 neuromast hair cell morphogenesis http://purl.obolibrary.org/obo/GO_0048667 cell morphogenesis involved in neuron differentiation The change in form (cell shape and size) that occurs when a neuromast hair cell progresses from its initial formation to its mature state. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. http://purl.obolibrary.org/obo/GO_0005996 monosaccharide metabolic process http://purl.obolibrary.org/obo/GO_0044281 small molecule metabolic process The chemical reactions and pathways involving monosaccharides, the simplest carbohydrates. They are polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides. http://purl.obolibrary.org/obo/GO_0035694 mitochondrial protein catabolic process http://purl.obolibrary.org/obo/GO_0030163 protein catabolic process The chemical reactions and pathways resulting in the breakdown of a mitochondrial protein. This process is necessary to maintain the healthy state of mitochondria and is thought to occur via the induction of an intramitochondrial lysosome-like organelle that acts to eliminate the damaged oxidised mitochondrial proteins without destroying the mitochondrial structure. http://purl.obolibrary.org/obo/GO_0006006 glucose metabolic process http://purl.obolibrary.org/obo/GO_0019318 hexose metabolic process The chemical reactions and pathways involving glucose, the aldohexose gluco-hexose. D-glucose is dextrorotatory and is sometimes known as dextrose; it is an important source of energy for living organisms and is found free as well as combined in homo- and hetero-oligosaccharides and polysaccharides. http://purl.obolibrary.org/obo/GO_0006007 glucose catabolic process http://purl.obolibrary.org/obo/GO_0019320 hexose catabolic process The chemical reactions and pathways resulting in the breakdown of glucose, the aldohexose gluco-hexose. http://purl.obolibrary.org/obo/GO_0035700 astrocyte chemotaxis http://purl.obolibrary.org/obo/GO_0043615 astrocyte cell migration The directed movement of an astrocyte guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis). http://purl.obolibrary.org/obo/GO_0006022 aminoglycan metabolic process http://purl.obolibrary.org/obo/GO_1901135 carbohydrate derivative metabolic process The chemical reactions and pathways involving aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages. http://purl.obolibrary.org/obo/GO_0035701 hematopoietic stem cell migration http://purl.obolibrary.org/obo/GO_0016477 cell migration The orderly movement of a hematopoietic stem cell from one site to another. A hematopoietic stem cell is a cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system. http://purl.obolibrary.org/obo/GO_0006023 aminoglycan biosynthetic process http://purl.obolibrary.org/obo/GO_0009059 macromolecule biosynthetic process The chemical reactions and pathways resulting in the formation of aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages. http://purl.obolibrary.org/obo/GO_0035702 monocyte homeostasis http://purl.obolibrary.org/obo/GO_0002262 myeloid cell homeostasis The process of regulating the proliferation and elimination of monocytes such that the total number of monocytes within a whole or part of an organism is stable over time in the absence of an outside stimulus. http://purl.obolibrary.org/obo/GO_0006024 glycosaminoglycan biosynthetic process http://purl.obolibrary.org/obo/GO_0030203 glycosaminoglycan metabolic process The chemical reactions and pathways resulting in the formation of glycosaminoglycans, any one of a group of linear polysaccharides composed of repeating disaccharide units. http://purl.obolibrary.org/obo/GO_0035704 helper T cell chemotaxis http://purl.obolibrary.org/obo/GO_0010818 T cell chemotaxis The directed movement of a helper T cell in response to an external stimulus. http://purl.obolibrary.org/obo/GO_0006026 aminoglycan catabolic process http://purl.obolibrary.org/obo/GO_0009057 macromolecule catabolic process The chemical reactions and pathways resulting in the breakdown of aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages. http://purl.obolibrary.org/obo/GO_0035705 T-helper 17 cell chemotaxis http://purl.obolibrary.org/obo/GO_0010818 T cell chemotaxis The directed movement of a T-helper 17 cell in response to an external stimulus. http://purl.obolibrary.org/obo/GO_0006027 glycosaminoglycan catabolic process http://purl.obolibrary.org/obo/GO_0030203 glycosaminoglycan metabolic process The chemical reactions and pathways resulting in the breakdown of glycosaminoglycans, any one of a group of linear polysaccharides composed of repeating disaccharide units. http://purl.obolibrary.org/obo/GO_0035706 T-helper 1 cell chemotaxis http://purl.obolibrary.org/obo/GO_0010818 T cell chemotaxis The directed movement of a T-helper 1 cell in response to an external stimulus. http://purl.obolibrary.org/obo/GO_0006029 proteoglycan metabolic process http://purl.obolibrary.org/obo/GO_0009100 glycoprotein metabolic process The chemical reactions and pathways involving proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans. http://purl.obolibrary.org/obo/GO_0035707 T-helper 2 cell chemotaxis http://purl.obolibrary.org/obo/GO_0010818 T cell chemotaxis The directed movement of a T-helper 2 cell in response to an external stimulus. http://purl.obolibrary.org/obo/GO_0006066 alcohol metabolic process http://purl.obolibrary.org/obo/GO_0044281 small molecule metabolic process The chemical reactions and pathways involving alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom. http://purl.obolibrary.org/obo/GO_0035709 memory T cell activation http://purl.obolibrary.org/obo/GO_0042110 T cell activation The change in morphology and behavior of a memory T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. http://purl.obolibrary.org/obo/GO_0035710 CD4-positive, alpha-beta T cell activation http://purl.obolibrary.org/obo/GO_0046631 alpha-beta T cell activation The change in morphology and behavior of a CD4-positive, alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. http://purl.obolibrary.org/obo/GO_0006081 aldehyde metabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process The chemical reactions and pathways involving aldehydes, any organic compound with the formula R-CH=O, as carried out by individual cells. http://purl.obolibrary.org/obo/GO_0006082 organic acid metabolic process http://purl.obolibrary.org/obo/GO_0044281 small molecule metabolic process The chemical reactions and pathways involving organic acids, any acidic compound containing carbon in covalent linkage. http://purl.obolibrary.org/obo/GO_0035711 T-helper 1 cell activation http://purl.obolibrary.org/obo/GO_0035710 CD4-positive, alpha-beta T cell activation The change in morphology and behavior of a T-helper 1 cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. http://purl.obolibrary.org/obo/GO_0035712 T-helper 2 cell activation http://purl.obolibrary.org/obo/GO_0035710 CD4-positive, alpha-beta T cell activation The change in morphology and behavior of a T helper 2 cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. http://purl.obolibrary.org/obo/GO_0006091 generation of precursor metabolites and energy http://purl.obolibrary.org/obo/GO_0008152 metabolic process The chemical reactions and pathways resulting in the formation of precursor metabolites, substances from which energy is derived, and any process involved in the liberation of energy from these substances. http://purl.obolibrary.org/obo/GO_0035719 tRNA import into nucleus http://purl.obolibrary.org/obo/GO_0051031 tRNA transport The directed movement of tRNA from the cytoplasm to the nucleus. http://purl.obolibrary.org/obo/GO_0006094 gluconeogenesis http://purl.obolibrary.org/obo/GO_0019319 hexose biosynthetic process The formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol. http://purl.obolibrary.org/obo/GO_0035733 hepatic stellate cell activation http://purl.obolibrary.org/obo/GO_0072537 fibroblast activation A change in the morphology or behavior of a hepatic stellate cell resulting from exposure to a cytokine, chemokine, hormone, cellular ligand or soluble factor. http://purl.obolibrary.org/obo/GO_0006109 regulation of carbohydrate metabolic process http://purl.obolibrary.org/obo/GO_0080090 regulation of primary metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving carbohydrates. http://purl.obolibrary.org/obo/GO_0006111 regulation of gluconeogenesis http://purl.obolibrary.org/obo/GO_0043255 regulation of carbohydrate biosynthetic process Any process that modulates the frequency, rate or extent of gluconeogenesis, the formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol. http://purl.obolibrary.org/obo/GO_0035735 intraciliary transport involved in cilium assembly http://purl.obolibrary.org/obo/GO_0042073 intraciliary transport The bidirectional movement of large protein complexes along microtubules within a cilium that contributes to cilium assembly. http://purl.obolibrary.org/obo/GO_0035736 cell proliferation involved in compound eye morphogenesis http://purl.obolibrary.org/obo/GO_0008283 cell population proliferation The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to compound eye morphogenesis. http://purl.obolibrary.org/obo/GO_0006112 energy reserve metabolic process http://purl.obolibrary.org/obo/GO_0015980 energy derivation by oxidation of organic compounds The chemical reactions and pathways by which a cell derives energy from stored compounds such as fats or glycogen. http://purl.obolibrary.org/obo/GO_0035739 CD4-positive, alpha-beta T cell proliferation http://purl.obolibrary.org/obo/GO_0035710 CD4-positive, alpha-beta T cell activation The expansion of a CD4-positive, alpha-beta T cell population by cell division. http://purl.obolibrary.org/obo/GO_0006139 nucleobase-containing compound metabolic process http://purl.obolibrary.org/obo/GO_0044238 primary metabolic process Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids. http://purl.obolibrary.org/obo/GO_0035740 CD8-positive, alpha-beta T cell proliferation http://purl.obolibrary.org/obo/GO_0036037 CD8-positive, alpha-beta T cell activation The expansion of a CD8-positive, alpha-beta T cell population by cell division. http://purl.obolibrary.org/obo/GO_0006140 regulation of nucleotide metabolic process http://purl.obolibrary.org/obo/GO_0051174 regulation of phosphorus metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleotides. http://purl.obolibrary.org/obo/GO_0035741 activated CD4-positive, alpha-beta T cell proliferation http://purl.obolibrary.org/obo/GO_0035739 CD4-positive, alpha-beta T cell proliferation The expansion of an activated CD4-positive, alpha-beta T cell population by cell division. http://purl.obolibrary.org/obo/GO_0006163 purine nucleotide metabolic process http://purl.obolibrary.org/obo/GO_0072521 purine-containing compound metabolic process The chemical reactions and pathways involving a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. http://purl.obolibrary.org/obo/GO_0035742 activated CD8-positive, alpha-beta T cell proliferation http://purl.obolibrary.org/obo/GO_0035740 CD8-positive, alpha-beta T cell proliferation The expansion of an activated CD8-positive, alpha-beta T cell population by cell division. http://purl.obolibrary.org/obo/GO_0006164 purine nucleotide biosynthetic process http://purl.obolibrary.org/obo/GO_0072522 purine-containing compound biosynthetic process The chemical reactions and pathways resulting in the formation of a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. http://purl.obolibrary.org/obo/GO_0035743 CD4-positive, alpha-beta T cell cytokine production http://purl.obolibrary.org/obo/GO_0002369 T cell cytokine production Any process that contributes to cytokine production by a CD4-positive, alpha-beta T cell. http://purl.obolibrary.org/obo/GO_0006172 ADP biosynthetic process http://purl.obolibrary.org/obo/GO_0046031 ADP metabolic process The chemical reactions and pathways resulting in the formation of ADP, adenosine 5'-diphosphate. http://purl.obolibrary.org/obo/GO_0035744 T-helper 1 cell cytokine production http://purl.obolibrary.org/obo/GO_0035743 CD4-positive, alpha-beta T cell cytokine production Any process that contributes to cytokine production by a T-helper 1 cell. http://purl.obolibrary.org/obo/GO_0006195 purine nucleotide catabolic process http://purl.obolibrary.org/obo/GO_0072523 purine-containing compound catabolic process The chemical reactions and pathways resulting in the breakdown of a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. http://purl.obolibrary.org/obo/GO_0035745 T-helper 2 cell cytokine production http://purl.obolibrary.org/obo/GO_0035743 CD4-positive, alpha-beta T cell cytokine production Any process that contributes to cytokine production by a T-helper 2 cell. http://purl.obolibrary.org/obo/GO_0035747 natural killer cell chemotaxis http://purl.obolibrary.org/obo/GO_0048247 lymphocyte chemotaxis The directed movement of a natural killer cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis). http://purl.obolibrary.org/obo/GO_0006309 apoptotic DNA fragmentation http://purl.obolibrary.org/obo/GO_0006308 DNA catabolic process The cleavage of DNA during apoptosis, which usually occurs in two stages: cleavage into fragments of about 50 kbp followed by cleavage between nucleosomes to yield 200 bp fragments. http://purl.obolibrary.org/obo/GO_0035754 B cell chemotaxis http://purl.obolibrary.org/obo/GO_0048247 lymphocyte chemotaxis The directed movement of a B cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis). http://purl.obolibrary.org/obo/GO_0006338 chromatin remodeling http://purl.obolibrary.org/obo/GO_0006325 chromatin organization A dynamic process of chromatin reorganization resulting in changes to chromatin structure. These changes allow DNA metabolic processes such as transcriptional regulation, DNA recombination, DNA repair, and DNA replication. http://purl.obolibrary.org/obo/GO_0035767 endothelial cell chemotaxis http://purl.obolibrary.org/obo/GO_0043542 endothelial cell migration The directed movement of an endothelial cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis). http://purl.obolibrary.org/obo/GO_0006399 tRNA metabolic process http://purl.obolibrary.org/obo/GO_0016070 RNA metabolic process The chemical reactions and pathways involving tRNA, transfer RNA, a class of relatively small RNA molecules responsible for mediating the insertion of amino acids into the sequence of nascent polypeptide chains during protein synthesis. Transfer RNA is characterized by the presence of many unusual minor bases, the function of which has not been completely established. http://purl.obolibrary.org/obo/GO_0035773 insulin secretion involved in cellular response to glucose stimulus http://purl.obolibrary.org/obo/GO_0030073 insulin secretion The regulated release of proinsulin from secretory granules (B granules) in the B cells of the pancreas; accompanied by cleavage of proinsulin to form mature insulin, in response to a glucose stimulus. http://purl.obolibrary.org/obo/GO_0006403 RNA localization http://purl.obolibrary.org/obo/GO_0033036 macromolecule localization A process in which RNA is transported to, or maintained in, a specific location. http://purl.obolibrary.org/obo/GO_0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus http://purl.obolibrary.org/obo/GO_0061178 regulation of insulin secretion involved in cellular response to glucose stimulus Any process that increases the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose. http://purl.obolibrary.org/obo/GO_0006404 RNA import into nucleus http://purl.obolibrary.org/obo/GO_0051170 import into nucleus The import of RNA from the cytoplasm to the nucleus. http://purl.obolibrary.org/obo/GO_0006405 RNA export from nucleus http://purl.obolibrary.org/obo/GO_0051168 nuclear export The directed movement of RNA from the nucleus to the cytoplasm. http://purl.obolibrary.org/obo/GO_0035775 pronephric glomerulus morphogenesis http://purl.obolibrary.org/obo/GO_0072102 glomerulus morphogenesis The process in which the anatomical structures of the pronephric glomerulus are generated and organized. The pronephric glomerulus is part of the pronephric nephron and is restricted to one body segment. http://purl.obolibrary.org/obo/GO_0006409 tRNA export from nucleus http://purl.obolibrary.org/obo/GO_0051031 tRNA transport The directed movement of tRNA from the nucleus to the cytoplasm. http://purl.obolibrary.org/obo/GO_0035776 pronephric proximal tubule development http://purl.obolibrary.org/obo/GO_0072014 proximal tubule development The progression of the pronephric proximal tubule over time, from its formation to the mature structure. A pronephric nephron tubule is an epithelial tube that is part of the pronephros. http://purl.obolibrary.org/obo/GO_0006417 regulation of translation http://purl.obolibrary.org/obo/GO_0051246 regulation of protein metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA. http://purl.obolibrary.org/obo/GO_0035777 pronephric distal tubule development http://purl.obolibrary.org/obo/GO_0072017 distal tubule development The process whose specific outcome is the progression of the pronephric distal tubule over time, from its formation to the mature structure. A pronephric nephron tubule is an epithelial tube that is part of the pronephros. http://purl.obolibrary.org/obo/GO_0006446 regulation of translational initiation http://purl.obolibrary.org/obo/GO_0006417 regulation of translation Any process that modulates the frequency, rate or extent of translational initiation. http://purl.obolibrary.org/obo/GO_0035778 pronephric nephron tubule epithelial cell differentiation http://purl.obolibrary.org/obo/GO_0072160 nephron tubule epithelial cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the pronephric nephron tubule as it progresses from its formation to the mature state. http://purl.obolibrary.org/obo/GO_0006448 regulation of translational elongation http://purl.obolibrary.org/obo/GO_0006417 regulation of translation Any process that modulates the frequency, rate, extent or accuracy of translational elongation. http://purl.obolibrary.org/obo/GO_0006449 regulation of translational termination http://purl.obolibrary.org/obo/GO_0043244 regulation of protein-containing complex disassembly Any process that modulates the frequency, rate or extent of translational termination. http://purl.obolibrary.org/obo/GO_0035779 angioblast cell differentiation http://purl.obolibrary.org/obo/GO_0048863 stem cell differentiation The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an angioblast cell. Angioblasts are one of the two products formed from hemangioblast cells (the other being pluripotent hemopoietic stem cells). http://purl.obolibrary.org/obo/GO_0006493 protein O-linked glycosylation http://purl.obolibrary.org/obo/GO_0009101 glycoprotein biosynthetic process A glycoprotein biosynthetic process starting with the covalent linkage of carbohydrate or carbohydrate derivative unit via a glycosidic bond to the oxygen atom of a serine, threonine, hydroxylysine, hydroxyproline or tyrosine side chain in a protein, which can be further elongated with the sequential addition of sugar units resulting in the formation of a protein O-linked glycan. http://purl.obolibrary.org/obo/GO_0035787 cell migration involved in kidney development http://purl.obolibrary.org/obo/GO_0016477 cell migration The orderly movement of a cell from one site to another that will contribute to the progression of the kidney over time, from its formation to the mature organ. http://purl.obolibrary.org/obo/GO_0035788 cell migration involved in metanephros development http://purl.obolibrary.org/obo/GO_0035787 cell migration involved in kidney development The orderly movement of a cell from one site to another that will contribute to the progression of the metanephric kidney over time, from its formation to the mature organ. http://purl.obolibrary.org/obo/GO_0006516 glycoprotein catabolic process http://purl.obolibrary.org/obo/GO_1901136 carbohydrate derivative catabolic process The chemical reactions and pathways resulting in the breakdown of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide. http://purl.obolibrary.org/obo/GO_0035799 ureter maturation http://purl.obolibrary.org/obo/GO_0048799 animal organ maturation A developmental process, independent of morphogenetic (shape) change, that is required for the ureter to attain its fully functional state. The ureter is a muscular tube that transports urine from the kidney to the urinary bladder or from the Malpighian tubule to the hindgut. http://purl.obolibrary.org/obo/GO_0006518 peptide metabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process The chemical reactions and pathways involving peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another. http://purl.obolibrary.org/obo/GO_0035801 adrenal cortex development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the adrenal cortex over time, from its formation to the mature structure. The adrenal cortex is located at the periphery of the adrenal gland and controls glucose and electrolyte metabolism, response to stress and sexual development through the production of different classes of steroid hormones (glucocorticoids, mineralocorticoids and androgens). http://purl.obolibrary.org/obo/GO_0006536 glutamate metabolic process http://purl.obolibrary.org/obo/GO_1901605 alpha-amino acid metabolic process The chemical reactions and pathways involving glutamate, the anion of 2-aminopentanedioic acid. http://purl.obolibrary.org/obo/GO_0006538 L-glutamate catabolic process http://purl.obolibrary.org/obo/GO_0170040 proteinogenic amino acid catabolic process The chemical reactions and pathways resulting in the breakdown of L-glutamate, the anion of 2-aminopentanedioic acid. http://purl.obolibrary.org/obo/GO_0035802 adrenal cortex formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process that gives rise to the adrenal cortex. This process pertains to the initial formation of a structure from unspecified parts. The adrenogonadal primordium from which the adrenal cortex is formed derives from a condensation of coelomic epithelial cells (the urogenital ridge; the same structure from which gonads and kidney also originate). http://purl.obolibrary.org/obo/GO_0006544 glycine metabolic process http://purl.obolibrary.org/obo/GO_0170039 proteinogenic amino acid metabolic process The chemical reactions and pathways involving glycine, aminoethanoic acid. http://purl.obolibrary.org/obo/GO_0006545 glycine biosynthetic process http://purl.obolibrary.org/obo/GO_0170038 proteinogenic amino acid biosynthetic process The chemical reactions and pathways resulting in the formation of glycine, aminoethanoic acid. http://purl.obolibrary.org/obo/GO_0035809 regulation of urine volume http://purl.obolibrary.org/obo/GO_0050878 regulation of body fluid levels Any process that modulates the amount of urine excreted from the body over a unit of time. http://purl.obolibrary.org/obo/GO_0006546 glycine catabolic process http://purl.obolibrary.org/obo/GO_0170040 proteinogenic amino acid catabolic process The chemical reactions and pathways resulting in the breakdown of glycine, aminoethanoic acid. http://purl.obolibrary.org/obo/GO_0035844 cloaca development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the cloaca over time, from it's formation to the mature structure. The cloaca is the common chamber into which intestinal, genital and urinary canals open in vertebrates. http://purl.obolibrary.org/obo/GO_0006548 L-histidine catabolic process http://purl.obolibrary.org/obo/GO_0170040 proteinogenic amino acid catabolic process The chemical reactions and pathways resulting in the breakdown of L-histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid. http://purl.obolibrary.org/obo/GO_0035846 oviduct epithelium development http://purl.obolibrary.org/obo/GO_0060429 epithelium development The progression of the oviduct epithelium over time from its initial formation to the mature structure. An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism. The oviduct epithelium is the specialized epithelium that lines the oviduct. http://purl.obolibrary.org/obo/GO_0006584 catecholamine metabolic process http://purl.obolibrary.org/obo/GO_0006576 biogenic amine metabolic process The chemical reactions and pathways involving any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine. http://purl.obolibrary.org/obo/GO_0035847 uterine epithelium development http://purl.obolibrary.org/obo/GO_0035846 oviduct epithelium development The progression of an epithelium of the uterus over time from its initial formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. http://purl.obolibrary.org/obo/GO_0006590 thyroid hormone generation http://purl.obolibrary.org/obo/GO_0042403 thyroid hormone metabolic process The formation of either of the compounds secreted by the thyroid gland, mainly thyroxine and triiodothyronine. This is achieved by the iodination and joining of tyrosine molecules to form the precursor thyroglobin, proteolysis of this precursor gives rise to the thyroid hormones. http://purl.obolibrary.org/obo/GO_0006611 protein export from nucleus http://purl.obolibrary.org/obo/GO_0006886 intracellular protein transport The directed movement of a protein from the nucleus into the cytoplasm. http://purl.obolibrary.org/obo/GO_0035848 oviduct morphogenesis http://purl.obolibrary.org/obo/GO_0009887 animal organ morphogenesis The process in which anatomical structures of the oviduct are generated and organized. An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism. http://purl.obolibrary.org/obo/GO_0006624 vacuolar protein processing http://purl.obolibrary.org/obo/GO_0016485 protein processing Protein processing that takes place in the vacuole. Most protein processing in the vacuole represents proteolytic cleavage of precursors to form active enzymes. http://purl.obolibrary.org/obo/GO_0035855 megakaryocyte development http://purl.obolibrary.org/obo/GO_0061515 myeloid cell development The process whose specific outcome is the progression of a megakaryocyte cell over time, from its formation to the mature structure. Megakaryocyte development does not include the steps involved in committing a cell to a megakaryocyte fate. A megakaryocyte is a giant cell 50 to 100 micron in diameter, with a greatly lobulated nucleus, found in the bone marrow. http://purl.obolibrary.org/obo/GO_0006629 lipid metabolic process http://purl.obolibrary.org/obo/GO_0044238 primary metabolic process The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids. http://purl.obolibrary.org/obo/GO_0035864 response to potassium ion http://purl.obolibrary.org/obo/GO_0010038 response to metal ion Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a potassium ion stimulus. http://purl.obolibrary.org/obo/GO_0006664 glycolipid metabolic process http://purl.obolibrary.org/obo/GO_1903509 liposaccharide metabolic process The chemical reactions and pathways involving glycolipids, a class of 1,2-di-O-acylglycerols joined at oxygen 3 by a glycosidic linkage to a carbohydrate part (usually a mono-, di- or tri-saccharide). Some substances classified as bacterial glycolipids have the sugar group acylated by one or more fatty acids and the glycerol group may be absent. http://purl.obolibrary.org/obo/GO_0035865 cellular response to potassium ion http://purl.obolibrary.org/obo/GO_0035864 response to potassium ion Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a potassium ion stimulus. http://purl.obolibrary.org/obo/GO_0006665 sphingolipid metabolic process http://purl.obolibrary.org/obo/GO_0006629 lipid metabolic process The chemical reactions and pathways involving sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid). http://purl.obolibrary.org/obo/GO_0035878 nail development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of a nail over time, from its formation to the mature structure. A nail is a horn-like envelope covering the outer end of a finger or toe, and consists of the nail plate, the nail matrix and the nail bed below it, and the grooves surrounding it. http://purl.obolibrary.org/obo/GO_0006694 steroid biosynthetic process http://purl.obolibrary.org/obo/GO_0008610 lipid biosynthetic process The chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus; includes de novo formation and steroid interconversion by modification. http://purl.obolibrary.org/obo/GO_0035881 amacrine cell differentiation http://purl.obolibrary.org/obo/GO_0021953 central nervous system neuron differentiation The process in which a relatively unspecialized cell acquires specialized features of an amacrine cell, an interneuron generated in the inner nuclear layer (INL) of the vertebrate retina. Amacrine cells integrate, modulate, and interpose a temporal domain in the visual message presented to the retinal ganglion cells, with which they synapse in the inner plexiform layer. Amacrine cells lack large axons. http://purl.obolibrary.org/obo/GO_0006699 bile acid biosynthetic process http://purl.obolibrary.org/obo/GO_0072330 monocarboxylic acid biosynthetic process The chemical reactions and pathways resulting in the formation of bile acids, any of a group of steroid carboxylic acids occurring in bile. http://purl.obolibrary.org/obo/GO_0035886 vascular associated smooth muscle cell differentiation http://purl.obolibrary.org/obo/GO_0051145 smooth muscle cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a vascular smooth muscle cell. http://purl.obolibrary.org/obo/GO_0006700 C21-steroid hormone biosynthetic process http://purl.obolibrary.org/obo/GO_0042446 hormone biosynthetic process The chemical reactions and pathways resulting in the formation of C21-steroid hormones, steroid compounds containing 21 carbons which function as hormones. http://purl.obolibrary.org/obo/GO_0035887 aortic smooth muscle cell differentiation http://purl.obolibrary.org/obo/GO_0035886 vascular associated smooth muscle cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell surrounding the aorta. http://purl.obolibrary.org/obo/GO_0006701 progesterone biosynthetic process http://purl.obolibrary.org/obo/GO_0042448 progesterone metabolic process The chemical reactions and pathways resulting in the formation of progesterone, a steroid hormone produced in the ovary which prepares and maintains the uterus for pregnancy. Also found in plants. http://purl.obolibrary.org/obo/GO_0035898 parathyroid hormone secretion http://purl.obolibrary.org/obo/GO_0060986 endocrine hormone secretion The regulated release of parathyroid hormone into the circulatory system. http://purl.obolibrary.org/obo/GO_0006704 glucocorticoid biosynthetic process http://purl.obolibrary.org/obo/GO_0008211 glucocorticoid metabolic process The chemical reactions and pathways resulting in the formation of glucocorticoids, hormonal C21 corticosteroids synthesized from cholesterol. http://purl.obolibrary.org/obo/GO_0035904 aorta development http://purl.obolibrary.org/obo/GO_0060840 artery development The progression of the aorta over time, from its initial formation to the mature structure. An aorta is an artery that carries blood from the heart to other parts of the body. http://purl.obolibrary.org/obo/GO_0006705 mineralocorticoid biosynthetic process http://purl.obolibrary.org/obo/GO_0042446 hormone biosynthetic process The chemical reactions and pathways resulting in the formation of mineralocorticoids, hormonal C21 corticosteroids synthesized from cholesterol. http://purl.obolibrary.org/obo/GO_0035905 ascending aorta development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the ascending aorta over time, from its initial formation to the mature structure. The ascending aorta is the portion of the aorta in a two-pass circulatory system that lies between the heart and the arch of aorta. In a two-pass circulatory system blood passes twice through the heart to supply the body once. http://purl.obolibrary.org/obo/GO_0006706 steroid catabolic process http://purl.obolibrary.org/obo/GO_0016042 lipid catabolic process The chemical reactions and pathways resulting in the breakdown of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus. http://purl.obolibrary.org/obo/GO_0035906 descending aorta development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the descending aorta over time, from its initial formation to the mature structure. The descending aorta is the portion of the aorta in a two-pass circulatory system from the arch of aorta to the point where it divides into the common iliac arteries. In a two-pass circulatory system blood passes twice through the heart to supply the body once. http://purl.obolibrary.org/obo/GO_0006709 progesterone catabolic process http://purl.obolibrary.org/obo/GO_0042448 progesterone metabolic process The chemical reactions and pathways resulting in the breakdown of progesterone, a steroid hormone produced in the ovary which prepares and maintains the uterus for pregnancy. Also found in plants. http://purl.obolibrary.org/obo/GO_0035907 dorsal aorta development http://purl.obolibrary.org/obo/GO_0035904 aorta development The progression of the dorsal aorta over time, from its initial formation to the mature structure. The dorsal aorta is a blood vessel in a single-pass circulatory system that carries oxygenated blood from the gills to the rest of the body. In a single-pass circulatory system blood passes once through the heart to supply the body once. http://purl.obolibrary.org/obo/GO_0006712 mineralocorticoid catabolic process http://purl.obolibrary.org/obo/GO_0042447 hormone catabolic process The chemical reactions and pathways resulting in the breakdown of mineralocorticoids, hormonal C21 corticosteroids synthesized from cholesterol. http://purl.obolibrary.org/obo/GO_0035909 aorta morphogenesis http://purl.obolibrary.org/obo/GO_0048844 artery morphogenesis The process in which the anatomical structures of an aorta are generated and organized. An aorta is an artery that carries blood from the heart to other parts of the body. http://purl.obolibrary.org/obo/GO_0006713 glucocorticoid catabolic process http://purl.obolibrary.org/obo/GO_0008211 glucocorticoid metabolic process The chemical reactions and pathways resulting in the breakdown of glucocorticoids, hormonal C21 corticosteroids synthesized from cholesterol. http://purl.obolibrary.org/obo/GO_0035910 ascending aorta morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structures of the ascending aorta are generated and organized. The ascending aorta is the portion of the aorta in a two-pass circulatory system that lies between the heart and the arch of aorta. In a two-pass circulatory system blood passes twice through the heart to supply the body once. http://purl.obolibrary.org/obo/GO_0006714 sesquiterpenoid metabolic process http://purl.obolibrary.org/obo/GO_0006721 terpenoid metabolic process The chemical reactions and pathways involving sesquiterpenoid compounds, terpenoids with three isoprene units. http://purl.obolibrary.org/obo/GO_0035911 descending aorta morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structures of the descending aorta are generated and organized. The descending aorta is the portion of the aorta in a two-pass circulatory system from the arch of aorta to the point where it divides into the common iliac arteries. In a two-pass circulatory system blood passes twice through the heart to supply the body once. http://purl.obolibrary.org/obo/GO_0006716 juvenile hormone metabolic process http://purl.obolibrary.org/obo/GO_0042445 hormone metabolic process The chemical reactions and pathways involving juvenile hormones, the three sesquiterpenoid derivatives that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis. http://purl.obolibrary.org/obo/GO_0035912 dorsal aorta morphogenesis http://purl.obolibrary.org/obo/GO_0035909 aorta morphogenesis The process in which the anatomical structures of the dorsal aorta are generated and organized. The dorsal aorta is a blood vessel in a single-pass circulatory system that carries oxygenated blood from the gills to the rest of the body. In a single-pass circulatory system blood passes once through the heart to supply the body once. http://purl.obolibrary.org/obo/GO_0006718 juvenile hormone biosynthetic process http://purl.obolibrary.org/obo/GO_0042446 hormone biosynthetic process The chemical reactions and pathways resulting in the formation of juvenile hormones, the three sesquiterpenoid derivatives that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis. http://purl.obolibrary.org/obo/GO_0035921 desmosome disassembly http://purl.obolibrary.org/obo/GO_0150147 cell-cell junction disassembly The controlled breakdown of a desmosome. A desmosome is a patch-like intercellular junction found in vertebrate tissues, consisting of parallel zones of two cell membranes, separated by an space of 25-35 nm, and having dense fibrillar plaques in the subjacent cytoplasm. http://purl.obolibrary.org/obo/GO_0006719 juvenile hormone catabolic process http://purl.obolibrary.org/obo/GO_0042447 hormone catabolic process The chemical reactions and pathways resulting in the breakdown of juvenile hormones, the three sesquiterpenoid derivatives that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis. http://purl.obolibrary.org/obo/GO_0035929 steroid hormone secretion http://purl.obolibrary.org/obo/GO_0140353 lipid export from cell The regulated release of any steroid that acts as a hormone into the circulatory system. http://purl.obolibrary.org/obo/GO_0006720 isoprenoid metabolic process http://purl.obolibrary.org/obo/GO_0006629 lipid metabolic process The chemical reactions and pathways involving isoprenoid compounds, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues. http://purl.obolibrary.org/obo/GO_0035930 corticosteroid hormone secretion http://purl.obolibrary.org/obo/GO_0035929 steroid hormone secretion The regulated release of any corticosteroid hormone into the circulatory system. http://purl.obolibrary.org/obo/GO_0006721 terpenoid metabolic process http://purl.obolibrary.org/obo/GO_0006720 isoprenoid metabolic process The chemical reactions and pathways involving terpenoids, any member of a class of compounds characterized by an isoprenoid chemical structure and including derivatives with various functional groups. http://purl.obolibrary.org/obo/GO_0035931 mineralocorticoid secretion http://purl.obolibrary.org/obo/GO_0035930 corticosteroid hormone secretion The regulated release of any mineralocorticoid into the circulatory system. Mineralocorticoids are a class of steroid hormones that regulate water and electrolyte metabolism. http://purl.obolibrary.org/obo/GO_0006753 nucleoside phosphate metabolic process http://purl.obolibrary.org/obo/GO_0055086 nucleobase-containing small molecule metabolic process The chemical reactions and pathways involving any phosphorylated nucleoside. http://purl.obolibrary.org/obo/GO_0035933 glucocorticoid secretion http://purl.obolibrary.org/obo/GO_0035930 corticosteroid hormone secretion The regulated release of any glucocorticoid hormone into the circulatory system. Glucocorticoids are a class of steroid hormones that regulate a variety of physiological processes, in particular control of the concentration of glucose in blood. http://purl.obolibrary.org/obo/GO_0006754 ATP biosynthetic process http://purl.obolibrary.org/obo/GO_0046034 ATP metabolic process The chemical reactions and pathways resulting in the formation of ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. http://purl.obolibrary.org/obo/GO_0035935 androgen secretion http://purl.obolibrary.org/obo/GO_0035929 steroid hormone secretion The regulated release of an androgen into the circulatory system. Androgens are steroid hormones that stimulate or control the development and maintenance of masculine characteristics in vertebrates. http://purl.obolibrary.org/obo/GO_0006793 phosphorus metabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process The chemical reactions and pathways involving the nonmetallic element phosphorus or compounds that contain phosphorus. http://purl.obolibrary.org/obo/GO_0035936 testosterone secretion http://purl.obolibrary.org/obo/GO_0140353 lipid export from cell The regulated release of testosterone into the circulatory system. Testosterone is an androgen having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-4-C-5. http://purl.obolibrary.org/obo/GO_0006796 phosphate-containing compound metabolic process http://purl.obolibrary.org/obo/GO_0006793 phosphorus metabolic process The chemical reactions and pathways involving the phosphate group, the anion or salt of any phosphoric acid. http://purl.obolibrary.org/obo/GO_0035938 estradiol secretion http://purl.obolibrary.org/obo/GO_0035929 steroid hormone secretion The regulated release of estradiol into the circulatory system. http://purl.obolibrary.org/obo/GO_0006801 superoxide metabolic process http://purl.obolibrary.org/obo/GO_0072593 reactive oxygen species metabolic process The chemical reactions and pathways involving superoxide, the superoxide anion O2- (superoxide free radical), or any compound containing this species. http://purl.obolibrary.org/obo/GO_0035981 tongue muscle cell differentiation http://purl.obolibrary.org/obo/GO_0098528 skeletal muscle fiber differentiation The process in which a relatively unspecialized cell acquires specialized features of a tongue muscle cell. http://purl.obolibrary.org/obo/GO_0006809 nitric oxide biosynthetic process http://purl.obolibrary.org/obo/GO_0009058 biosynthetic process The chemical reactions and pathways resulting in the formation of nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water. http://purl.obolibrary.org/obo/GO_0035990 tendon cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a tendon cell. Tendon cell are elongated fibrocytes in which the cytoplasm is stretched between the collagen fibres of the tendon. Tendon cells have a central cell nucleus with a prominent nucleolus, a well-developed rough endoplasmic reticulum, and are responsible for synthesis and turnover of tendon fibres and ground substance. http://purl.obolibrary.org/obo/GO_0006810 transport http://purl.obolibrary.org/obo/GO_0051234 establishment of localization The directed movement of substances (such as macromolecules, small molecules, ions) or cellular components (such as complexes and organelles) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or a transporter complex, a pore or a motor protein. http://purl.obolibrary.org/obo/GO_0035992 tendon formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process that gives rise to a tendon. This process pertains to the initial formation of a tendon from unspecified parts. http://purl.obolibrary.org/obo/GO_0006811 monoatomic ion transport http://purl.obolibrary.org/obo/GO_0006810 transport The directed movement of a monoatomic ion into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Monatomic ions (also called simple ions) are ions consisting of exactly one atom. http://purl.obolibrary.org/obo/GO_0035993 deltoid tuberosity development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the deltoid tuberosity over time, from its formation to the mature structure. The deltoid tuberosity is the region on the shaft of the humerus to which the deltoid muscle attaches. The deltoid tuberosity develops through endochondral ossification in a two-phase process; an initiating tendon-dependent phase, and a muscle-dependent growth phase. http://purl.obolibrary.org/obo/GO_0006812 monoatomic cation transport http://purl.obolibrary.org/obo/GO_0006811 monoatomic ion transport The directed movement of a monoatomic cation, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Monatomic cations (also called simple cations) are positively charged ions consisting of exactly one atom. http://purl.obolibrary.org/obo/GO_0036022 limb joint morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structures of a limb joint are generated and organized. A limb joint is a flexible region that separates the rigid sections of a limb to allow movement in a controlled manner. http://purl.obolibrary.org/obo/GO_0006813 potassium ion transport http://purl.obolibrary.org/obo/GO_0030001 metal ion transport The directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0036035 osteoclast development http://purl.obolibrary.org/obo/GO_0061515 myeloid cell development The process whose specific outcome is the progression of a osteoclast from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue. http://purl.obolibrary.org/obo/GO_0006817 phosphate ion transport http://purl.obolibrary.org/obo/GO_0015698 inorganic anion transport The directed movement of phosphate ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0036037 CD8-positive, alpha-beta T cell activation http://purl.obolibrary.org/obo/GO_0046631 alpha-beta T cell activation The change in morphology and behavior of a CD8-positive, alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. http://purl.obolibrary.org/obo/GO_0006826 iron ion transport http://purl.obolibrary.org/obo/GO_0000041 transition metal ion transport The directed movement of iron (Fe) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0036053 glomerular endothelium fenestra http://purl.obolibrary.org/obo/GO_0046930 pore complex A large plasma membrane-lined circular pore that perforates the flattened glomerular endothelium and, unlike those of other fenestrated capillaries, is not spanned by diaphragms; the density and size of glomerular fenestrae account, at least in part, for the high permeability of the glomerular capillary wall to water and small solutes. http://purl.obolibrary.org/obo/GO_0006835 dicarboxylic acid transport http://purl.obolibrary.org/obo/GO_0046942 carboxylic acid transport The directed movement of dicarboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0036098 male germ-line stem cell population maintenance http://purl.obolibrary.org/obo/GO_0030718 germ-line stem cell population maintenance The process by which an organism or tissue maintains a population of male germ-line stem cells. http://purl.obolibrary.org/obo/GO_0006851 mitochondrial calcium ion transmembrane transport http://purl.obolibrary.org/obo/GO_0070588 calcium ion transmembrane transport The process in which a calcium ion (Ca2+) is transported across a mitochondrial membrane, into or out of the mitochondrion. http://purl.obolibrary.org/obo/GO_0036099 female germ-line stem cell population maintenance http://purl.obolibrary.org/obo/GO_0030718 germ-line stem cell population maintenance The process by which an organism or tissue maintains a population of female germ-line stem cells. http://purl.obolibrary.org/obo/GO_0006858 extracellular transport http://purl.obolibrary.org/obo/GO_0006810 transport The transport of substances that occurs outside cells. http://purl.obolibrary.org/obo/GO_0036135 Schwann cell migration http://purl.obolibrary.org/obo/GO_0008347 glial cell migration The orderly movement of a Schwann cell from one site to another. A Schwann cell is a glial cell that ensheathes axons of neuron in the peripheral nervous system and is necessary for their maintenance and function. http://purl.obolibrary.org/obo/GO_0006860 extracellular amino acid transport http://purl.obolibrary.org/obo/GO_0006865 amino acid transport The directed extracellular movement of amino acids. http://purl.obolibrary.org/obo/GO_0036145 dendritic cell homeostasis http://purl.obolibrary.org/obo/GO_0001776 leukocyte homeostasis The process of regulating the proliferation and elimination of dendritic cells such that the total number of dendritic cells within a whole or part of an organism is stable over time in the absence of an outside stimulus. http://purl.obolibrary.org/obo/GO_0006862 nucleotide transport http://purl.obolibrary.org/obo/GO_0015748 organophosphate ester transport The directed movement of a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate, into, out of or within a cell. http://purl.obolibrary.org/obo/GO_0036156 inner dynein arm http://purl.obolibrary.org/obo/GO_0005858 axonemal dynein complex Inner arm structure present on the outer doublet microtubules of ciliary and flagellar axonemes. The structure of inner dynein arms is complex and may vary within the axoneme. Inner dynein arms are heteromeric, comprising 8 different heavy chains and various subunits. Inner and outer dynein arms have different functions in the generation of microtubule-based motility. http://purl.obolibrary.org/obo/GO_0006873 intracellular monoatomic ion homeostasis http://purl.obolibrary.org/obo/GO_0055082 intracellular chemical homeostasis A homeostatic process involved in the maintenance of a steady state level of monoatomic ions within a cell. Monatomic ions (also called simple ions) are ions consisting of exactly one atom. http://purl.obolibrary.org/obo/GO_0036157 outer dynein arm http://purl.obolibrary.org/obo/GO_0005858 axonemal dynein complex Outer arm structure present on the outer doublet microtubules of ciliary and flagellar axonemes. Outer dynein arms contain 2-3 heavy chains, two or more intermediate chains and a cluster of 4-8 light chains. Inner and outer dynein arms have different functions in the generation of microtubule-based motility. http://purl.obolibrary.org/obo/GO_0006874 intracellular calcium ion homeostasis http://purl.obolibrary.org/obo/GO_0055074 calcium ion homeostasis A homeostatic process involved in the maintenance of a steady state level of calcium ions within a cell. http://purl.obolibrary.org/obo/GO_0036158 outer dynein arm assembly http://purl.obolibrary.org/obo/GO_0070286 axonemal dynein complex assembly The aggregation, arrangement and bonding together of a set of components to form an axonemal dynein outer arm, an outer arm structure present on the outer doublet microtubules of ciliary and flagellar axonemes. http://purl.obolibrary.org/obo/GO_0006879 intracellular iron ion homeostasis http://purl.obolibrary.org/obo/GO_0098771 inorganic ion homeostasis A homeostatic process involved in the maintenance of a steady state level of iron ions within a cell. http://purl.obolibrary.org/obo/GO_0036159 inner dynein arm assembly http://purl.obolibrary.org/obo/GO_0070286 axonemal dynein complex assembly The aggregation, arrangement and bonding together of a set of components to form an axonemal dynein inner arm, an inner arm structure present on the outer doublet microtubules of ciliary and flagellar axonemes. http://purl.obolibrary.org/obo/GO_0006883 intracellular sodium ion homeostasis http://purl.obolibrary.org/obo/GO_0055078 sodium ion homeostasis A homeostatic process involved in the maintenance of a steady state level of sodium ions within a cell. http://purl.obolibrary.org/obo/GO_0036160 melanocyte-stimulating hormone secretion http://purl.obolibrary.org/obo/GO_0030072 peptide hormone secretion The regulated release of a melanocyte-stimulating hormone, any of a group of peptide hormones that are produced by cells in the intermediate lobe of the pituitary gland, and stimulate the production of melanin to increase pigmentation. http://purl.obolibrary.org/obo/GO_0006884 cell volume homeostasis http://purl.obolibrary.org/obo/GO_0019725 cellular homeostasis Any process involved in maintaining the steady state of a cell's volume. The cell's volume refers to the three-dimensional space occupied by a cell. http://purl.obolibrary.org/obo/GO_0036161 calcitonin secretion http://purl.obolibrary.org/obo/GO_0030072 peptide hormone secretion The regulated release of calcitonin, a peptide hormone that participates in calcium and phosphorus metabolism, from a cell. http://purl.obolibrary.org/obo/GO_0006887 exocytosis http://purl.obolibrary.org/obo/GO_0032940 secretion by cell A process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle. Exocytosis can occur either by full fusion, when the vesicle collapses into the plasma membrane, or by a kiss-and-run mechanism that involves the formation of a transient contact, a pore, between a granule (for example of chromaffin cells) and the plasma membrane. The latter process most of the time leads to only partial secretion of the granule content. Exocytosis begins with steps that prepare vesicles for fusion with the membrane (tethering and docking) and ends when molecules are secreted from the cell. http://purl.obolibrary.org/obo/GO_0036162 oxytocin production http://purl.obolibrary.org/obo/GO_0010467 gene expression The appearance of oxytocin, a cyclic nonapeptide hormone with amino acid sequence CYIQNCPLG, due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Oxytocin is the principal uterine-contracting and milk-ejecting hormone of the posterior pituitary, and together with the neuropeptide vasopressin, is believed to influence social cognition and behavior. It also acts as a neurotransmitter in the brain. http://purl.obolibrary.org/obo/GO_0006892 post-Golgi vesicle-mediated transport http://purl.obolibrary.org/obo/GO_0048193 Golgi vesicle transport The directed movement of substances from the Golgi to other parts of the cell, including organelles and the plasma membrane, mediated by small transport vesicles. http://purl.obolibrary.org/obo/GO_0036179 osteoclast maturation http://purl.obolibrary.org/obo/GO_0048469 cell maturation A developmental process, independent of morphogenetic (shape) change, that is required for an osteoclast cell to attain its fully functional state. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue, and which typically differentiates from monocytes. http://purl.obolibrary.org/obo/GO_0006893 Golgi to plasma membrane transport http://purl.obolibrary.org/obo/GO_0098876 vesicle-mediated transport to the plasma membrane The directed movement of substances from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane. Golgi to plasma membrane transport precedes exocytosis. http://purl.obolibrary.org/obo/GO_0036194 muscle cell projection http://purl.obolibrary.org/obo/GO_0120025 plasma membrane bounded cell projection A prolongation or process extending from a muscle cell. A muscle cell is a mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns. http://purl.obolibrary.org/obo/GO_0006896 Golgi to vacuole transport http://purl.obolibrary.org/obo/GO_0007034 vacuolar transport The directed movement of substances from the Golgi to the vacuole. http://purl.obolibrary.org/obo/GO_0036195 muscle cell projection membrane http://purl.obolibrary.org/obo/GO_0031253 cell projection membrane The portion of the plasma membrane surrounding a muscle cell projection. http://purl.obolibrary.org/obo/GO_0006897 endocytosis http://purl.obolibrary.org/obo/GO_0098657 import into cell A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a part of the plasma membrane to form a new membrane-bounded vesicle. http://purl.obolibrary.org/obo/GO_0036230 granulocyte activation http://purl.obolibrary.org/obo/GO_0002274 myeloid leukocyte activation The change in morphology and behavior of a granulocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. http://purl.obolibrary.org/obo/GO_0006900 vesicle budding from membrane http://purl.obolibrary.org/obo/GO_0016050 vesicle organization The evagination of a membrane, resulting in formation of a vesicle. http://purl.obolibrary.org/obo/GO_0036304 umbilical cord morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structures of the umbilical cord are generated and organized. The umbilical cord is an organ or embryonic origin consisting of the 2 umbilical arteries and the one umbilical vein. The umbilical cord connects the cardiovascular system of the fetus to the mother via the placenta. http://purl.obolibrary.org/obo/GO_0006903 vesicle targeting http://purl.obolibrary.org/obo/GO_0009987 cellular process The process in which vesicles are directed to specific destination membranes. Targeting involves coordinated interactions among cytoskeletal elements (microtubules or actin filaments), motor proteins, molecules at the vesicle membrane and target membrane surfaces, and vesicle cargo. http://purl.obolibrary.org/obo/GO_0036305 ameloblast differentiation http://purl.obolibrary.org/obo/GO_0002065 columnar/cuboidal epithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of an ameloblast, a cylindrical epithelial cell in the innermost layer of the enamel organ. http://purl.obolibrary.org/obo/GO_0006906 vesicle fusion http://purl.obolibrary.org/obo/GO_0090174 organelle membrane fusion Fusion of the membrane of a transport vesicle with its target membrane. http://purl.obolibrary.org/obo/GO_0036321 ghrelin secretion http://purl.obolibrary.org/obo/GO_0030072 peptide hormone secretion The regulated release of ghrelin from a cell. Ghrelin is a 28 amino acid hunger-stimulating peptide hormone. http://purl.obolibrary.org/obo/GO_0006921 cellular component disassembly involved in execution phase of apoptosis http://purl.obolibrary.org/obo/GO_0022411 cellular component disassembly The breakdown of structures such as organelles, proteins, or other macromolecular structures during apoptosis. http://purl.obolibrary.org/obo/GO_0006935 chemotaxis http://purl.obolibrary.org/obo/GO_0042330 taxis The directed movement of a motile cell or organism, or the directed growth of a cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis). http://purl.obolibrary.org/obo/GO_0036322 pancreatic polypeptide secretion http://purl.obolibrary.org/obo/GO_0030072 peptide hormone secretion The regulated release of pancreatic polypeptide (PP) from a cell. Pancreatic polypeptide is a 36 amino acid polypeptide secreted by islets of Langerhans cells in the pancreas. http://purl.obolibrary.org/obo/GO_0006936 muscle contraction http://purl.obolibrary.org/obo/GO_0003012 muscle system process A process in which force is generated within muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. http://purl.obolibrary.org/obo/GO_0036333 hepatocyte homeostasis http://purl.obolibrary.org/obo/GO_0048872 homeostasis of number of cells Any biological process involved in the maintenance of the steady-state number of hepatocytes within a population of cells. Hepatocytes are specialized epithelial cells of the liver that are organized into interconnected plates called lobules. http://purl.obolibrary.org/obo/GO_0006937 regulation of muscle contraction http://purl.obolibrary.org/obo/GO_0090257 regulation of muscle system process Any process that modulates the frequency, rate or extent of muscle contraction. http://purl.obolibrary.org/obo/GO_0036334 epidermal stem cell homeostasis http://purl.obolibrary.org/obo/GO_0048872 homeostasis of number of cells Any biological process involved in the maintenance of the steady-state number of epidermal stem cells within a population of cells. http://purl.obolibrary.org/obo/GO_0006939 smooth muscle contraction http://purl.obolibrary.org/obo/GO_0006936 muscle contraction A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Smooth muscle differs from striated muscle in the much higher actin/myosin ratio, the absence of conspicuous sarcomeres and the ability to contract to a much smaller fraction of its resting length. http://purl.obolibrary.org/obo/GO_0036342 post-anal tail morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which a post-anal tail is generated and organized. A post-anal tail is a muscular region of the body that extends posterior to the anus. The post-anal tail may aid locomotion and balance. http://purl.obolibrary.org/obo/GO_0006942 regulation of striated muscle contraction http://purl.obolibrary.org/obo/GO_0006937 regulation of muscle contraction Any process that modulates the frequency, rate or extent of striated muscle contraction. http://purl.obolibrary.org/obo/GO_0036345 platelet maturation http://purl.obolibrary.org/obo/GO_0048469 cell maturation A developmental process, independent of morphogenetic (shape) change, that is required for a platelet to attain its fully functional state. A platelet is a non-nucleated disk-shaped cell formed by extrusion from megakaryocytes, found in the blood of all mammals, and mainly involved in blood coagulation. http://purl.obolibrary.org/obo/GO_0036376 sodium ion export across plasma membrane http://purl.obolibrary.org/obo/GO_0140115 export across plasma membrane The directed movement of sodium ions from inside of a cell, across the plasma membrane and into the extracellular region. http://purl.obolibrary.org/obo/GO_0006996 organelle organization http://purl.obolibrary.org/obo/GO_0016043 cellular component organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an organelle within a cell. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane. http://purl.obolibrary.org/obo/GO_0036444 calcium import into the mitochondrion http://purl.obolibrary.org/obo/GO_0006851 mitochondrial calcium ion transmembrane transport A process in which a calcium ion (Ca2+) is transported from the cytosol into the mitochondrial matrix. http://purl.obolibrary.org/obo/GO_0036446 myofibroblast differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which an undifferentiated cell acquires the features of a myofibroblast cell. http://purl.obolibrary.org/obo/GO_0006998 nuclear envelope organization http://purl.obolibrary.org/obo/GO_0061024 membrane organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear envelope. http://purl.obolibrary.org/obo/GO_0036457 keratohyalin granule http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure A cytoplasmic, non-membrane bound granule of, at least, keratinocyte. Associated to keratin intermediate filaments and partially crosslinked to the cell envelope. http://purl.obolibrary.org/obo/GO_0007000 nucleolus organization http://purl.obolibrary.org/obo/GO_0006997 nucleus organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleolus. http://purl.obolibrary.org/obo/GO_0036484 trunk neural crest cell migration http://purl.obolibrary.org/obo/GO_0001755 neural crest cell migration The characteristic movement of trunk neural crest cells from the neural tube to other locations in the vertebrate embryo. http://purl.obolibrary.org/obo/GO_0007006 mitochondrial membrane organization http://purl.obolibrary.org/obo/GO_0007005 mitochondrion organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrial membrane, either of the lipid bilayer surrounding a mitochondrion. http://purl.obolibrary.org/obo/GO_0036504 Golgi membrane fusion http://purl.obolibrary.org/obo/GO_0090174 organelle membrane fusion The joining of two lipid bilayers that surround the Golgi apparatus to form a single Golgi membrane. http://purl.obolibrary.org/obo/GO_0007008 outer mitochondrial membrane organization http://purl.obolibrary.org/obo/GO_0007006 mitochondrial membrane organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the mitochondrial outer membrane. http://purl.obolibrary.org/obo/GO_0036520 astrocyte-dopaminergic neuron signaling http://purl.obolibrary.org/obo/GO_0150098 glial cell-neuron signaling Cell-cell signaling that mediates the transfer of information from an astrocyte to a dopaminergic neuron. http://purl.obolibrary.org/obo/GO_0007015 actin filament organization http://purl.obolibrary.org/obo/GO_0097435 supramolecular fiber organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments. Includes processes that control the spatial distribution of actin filaments, such as organizing filaments into meshworks, bundles, or other structures, as by cross-linking. http://purl.obolibrary.org/obo/GO_0038169 somatostatin receptor signaling pathway http://purl.obolibrary.org/obo/GO_0007186 G protein-coupled receptor signaling pathway A G protein-coupled receptor signaling pathway initiated by somatostatin binding to the somatostatin receptor (SSTR) on the surface of a target cell, and ending with the regulation of a downstream cellular process. http://purl.obolibrary.org/obo/GO_0007019 microtubule depolymerization http://purl.obolibrary.org/obo/GO_0097435 supramolecular fiber organization The removal of tubulin heterodimers from one or both ends of a microtubule. http://purl.obolibrary.org/obo/GO_0039006 pronephric nephron tubule formation http://purl.obolibrary.org/obo/GO_0072079 nephron tubule formation The developmental process pertaining to the initial formation of a pronephric nephron tubule from unspecified parts. A pronephric nephron tubule is an epithelial tube that is part of a nephron in the pronephros. http://purl.obolibrary.org/obo/GO_0007020 microtubule nucleation http://purl.obolibrary.org/obo/GO_0000226 microtubule cytoskeleton organization The process in which tubulin alpha-beta heterodimers begin aggregation to form an oligomeric tubulin structure (a microtubule seed). Microtubule nucleation is the initiating step in the formation of a microtubule in the absence of any existing microtubules ('de novo' microtubule formation). http://purl.obolibrary.org/obo/GO_0039007 pronephric nephron morphogenesis http://purl.obolibrary.org/obo/GO_0072028 nephron morphogenesis The process in which the anatomical structures of the pronephric nephron are generated and organized. A pronephric nephron is the functional unit of the pronephros. http://purl.obolibrary.org/obo/GO_0007026 negative regulation of microtubule depolymerization http://purl.obolibrary.org/obo/GO_1902904 negative regulation of supramolecular fiber organization Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule depolymerization; prevention of depolymerization of a microtubule can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol. http://purl.obolibrary.org/obo/GO_0039008 pronephric nephron tubule morphogenesis http://purl.obolibrary.org/obo/GO_0072078 nephron tubule morphogenesis The process in which the anatomical structures of a pronephric nephron tubule are generated and organized from an epithelium. A pronephric nephron tubule is an epithelial tube that is part of the pronephric nephron. http://purl.obolibrary.org/obo/GO_0007027 negative regulation of axonemal microtubule depolymerization http://purl.obolibrary.org/obo/GO_0120035 regulation of plasma membrane bounded cell projection organization Any process that stops, prevents, or reduces the frequency, rate or extent of the depolymerization of the specialized microtubules of the axoneme. http://purl.obolibrary.org/obo/GO_0039011 pronephric proximal tubule morphogenesis http://purl.obolibrary.org/obo/GO_0072158 proximal tubule morphogenesis The process in which the anatomical structures of a pronephric nephron proximal tubule are generated and organized. A pronephric nephron tubule is an epithelial tube that is part of the pronephros. http://purl.obolibrary.org/obo/GO_0007028 cytoplasm organization http://purl.obolibrary.org/obo/GO_0016043 cellular component organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the cytoplasm. The cytoplasm is all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. http://purl.obolibrary.org/obo/GO_0039013 pronephric distal tubule morphogenesis http://purl.obolibrary.org/obo/GO_0072156 distal tubule morphogenesis The process in which the anatomical structures of a pronephric nephron distal tubule are generated and organized. A pronephric nephron tubule is an epithelial tube that is part of the pronephros. http://purl.obolibrary.org/obo/GO_0007030 Golgi organization http://purl.obolibrary.org/obo/GO_0006996 organelle organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the Golgi apparatus. http://purl.obolibrary.org/obo/GO_0039015 cell proliferation involved in pronephros development http://purl.obolibrary.org/obo/GO_0072111 cell proliferation involved in kidney development The multiplication or reproduction of cells, resulting in the expansion of the population in the pronephros. http://purl.obolibrary.org/obo/GO_0007034 vacuolar transport http://purl.obolibrary.org/obo/GO_0046907 intracellular transport The directed movement of substances into, out of or within a vacuole. http://purl.obolibrary.org/obo/GO_0007036 vacuolar calcium ion homeostasis http://purl.obolibrary.org/obo/GO_0006874 intracellular calcium ion homeostasis Any process involved in the maintenance of an internal steady state of calcium ions in the vacuole or between a vacuole and its surroundings. http://purl.obolibrary.org/obo/GO_0039019 pronephric nephron development http://purl.obolibrary.org/obo/GO_0072006 nephron development The process whose specific outcome is the progression of the pronephric nephron over time, from its formation to the mature structure. A pronephric nephron is the functional unit of the pronephros. http://purl.obolibrary.org/obo/GO_0007039 protein catabolic process in the vacuole http://purl.obolibrary.org/obo/GO_0030163 protein catabolic process The chemical reactions and pathways resulting in the breakdown of a protein in the vacuole, usually by the action of vacuolar proteases. http://purl.obolibrary.org/obo/GO_0039020 pronephric nephron tubule development http://purl.obolibrary.org/obo/GO_0072080 nephron tubule development The process whose specific outcome is the progression of a pronephric nephron tubule over time, from its formation to the mature structure. The pronephric nephron tubule is an epithelial tube that is part of the pronephric nephron and connects the filtration unit (glomerulus or glomus) of the pronephros to the pronephric duct. http://purl.obolibrary.org/obo/GO_0007041 lysosomal transport http://purl.obolibrary.org/obo/GO_0007034 vacuolar transport The directed movement of substances into, out of or within a lysosome. http://purl.obolibrary.org/obo/GO_0039021 pronephric glomerulus development http://purl.obolibrary.org/obo/GO_0032835 glomerulus development The progression of the glomerulus of the pronephric kidney over time from its initial formation until its mature state. The pronephric glomerulus is part of the pronephric nephron and is restricted to one body segment. http://purl.obolibrary.org/obo/GO_0007044 cell-substrate junction assembly http://purl.obolibrary.org/obo/GO_0150115 cell-substrate junction organization The aggregation, arrangement and bonding together of a set of components to form a junction between a cell and its substrate. http://purl.obolibrary.org/obo/GO_0039022 pronephric duct development http://purl.obolibrary.org/obo/GO_0072176 nephric duct development The process whose specific outcome is the progression of the pronephric duct over time, from its formation to the mature structure. The pronephric duct collects the filtrate from the pronephric tubules and opens to the exterior of the pronephric kidney. http://purl.obolibrary.org/obo/GO_0007059 chromosome segregation http://purl.obolibrary.org/obo/GO_0022402 cell cycle process The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles. http://purl.obolibrary.org/obo/GO_0039023 pronephric duct morphogenesis http://purl.obolibrary.org/obo/GO_0072178 nephric duct morphogenesis The process in which the anatomical structures of the pronephric duct are generated and organized. The pronephric duct collects the filtrate from the pronephric tubules and opens to the exterior of the kidney. http://purl.obolibrary.org/obo/GO_0007076 mitotic chromosome condensation http://purl.obolibrary.org/obo/GO_1903047 mitotic cell cycle process The cell cycle process in which chromatin structure is compacted prior to and during mitosis in eukaryotic cells. http://purl.obolibrary.org/obo/GO_0040012 regulation of locomotion http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process Any process that modulates the frequency, rate or extent of locomotion of a cell or organism. http://purl.obolibrary.org/obo/GO_0007077 mitotic nuclear membrane disassembly http://purl.obolibrary.org/obo/GO_1903047 mitotic cell cycle process The mitotic cell cycle process in which the controlled partial or complete breakdown of the nuclear membranes during occurs during mitosis. http://purl.obolibrary.org/obo/GO_0040013 negative regulation of locomotion http://purl.obolibrary.org/obo/GO_0040012 regulation of locomotion Any process that stops, prevents, or reduces the frequency, rate or extent of locomotion of a cell or organism. http://purl.obolibrary.org/obo/GO_0007088 regulation of mitotic nuclear division http://purl.obolibrary.org/obo/GO_0051783 regulation of nuclear division Any process that modulates the frequency, rate or extent of mitosis. http://purl.obolibrary.org/obo/GO_0040014 regulation of multicellular organism growth http://purl.obolibrary.org/obo/GO_0048638 regulation of developmental growth Any process that modulates the frequency, rate or extent of growth of the body of an organism so that it reaches its usual body size. http://purl.obolibrary.org/obo/GO_0007113 endomitotic cell cycle http://purl.obolibrary.org/obo/GO_0000278 mitotic cell cycle A mitotic cell cycle in which chromosomes are replicated and sister chromatids separate, but spindle formation, nuclear membrane breakdown and nuclear division do not occur, resulting in an increased number of chromosomes in the cell. http://purl.obolibrary.org/obo/GO_0040015 negative regulation of multicellular organism growth http://purl.obolibrary.org/obo/GO_0040014 regulation of multicellular organism growth Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organism to reach its usual body size. http://purl.obolibrary.org/obo/GO_0007135 meiosis II http://purl.obolibrary.org/obo/GO_0061983 meiosis II cell cycle process The second nuclear division of meiosis, in which the two chromatids in each chromosome are separated, resulting in four daughter nuclei from the two nuclei produced in meiosis II. http://purl.obolibrary.org/obo/GO_0040016 embryonic cleavage http://purl.obolibrary.org/obo/GO_0051301 cell division The first few specialized divisions of an activated animal egg. http://purl.obolibrary.org/obo/GO_0007140 male meiotic nuclear division http://purl.obolibrary.org/obo/GO_0140013 meiotic nuclear division A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the male germline. http://purl.obolibrary.org/obo/GO_0040017 positive regulation of locomotion http://purl.obolibrary.org/obo/GO_0040012 regulation of locomotion Any process that activates or increases the frequency, rate or extent of locomotion of a cell or organism. http://purl.obolibrary.org/obo/GO_0007142 male meiosis II http://purl.obolibrary.org/obo/GO_0007140 male meiotic nuclear division A cell cycle process comprising the steps by which a cell progresses through male meiosis II, the second meiotic division in the male germline. http://purl.obolibrary.org/obo/GO_0040018 positive regulation of multicellular organism growth http://purl.obolibrary.org/obo/GO_0048639 positive regulation of developmental growth Any process that activates or increases the frequency, rate or extent of growth of an organism to reach its usual body size. http://purl.obolibrary.org/obo/GO_0007143 female meiotic nuclear division http://purl.obolibrary.org/obo/GO_0140013 meiotic nuclear division A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the female germline. http://purl.obolibrary.org/obo/GO_0040019 positive regulation of embryonic development http://purl.obolibrary.org/obo/GO_0051240 positive regulation of multicellular organismal process Any process that activates or increases the frequency, rate or extent of embryonic development. http://purl.obolibrary.org/obo/GO_0007147 female meiosis II http://purl.obolibrary.org/obo/GO_0007143 female meiotic nuclear division The cell cycle process in which the second meiotic division occurs in the female germline. http://purl.obolibrary.org/obo/GO_0040034 regulation of development, heterochronic http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the consistent predetermined time point at which an integrated living unit or organism progresses from an initial condition to a later condition and the rate at which this time point is reached. http://purl.obolibrary.org/obo/GO_0007159 leukocyte cell-cell adhesion http://purl.obolibrary.org/obo/GO_0098609 cell-cell adhesion The attachment of a leukocyte to another cell via adhesion molecules. http://purl.obolibrary.org/obo/GO_0042045 epithelial fluid transport http://purl.obolibrary.org/obo/GO_0070633 transepithelial transport The directed movement of fluid across epithelia. http://purl.obolibrary.org/obo/GO_0007162 negative regulation of cell adhesion http://purl.obolibrary.org/obo/GO_0030155 regulation of cell adhesion Any process that stops, prevents, or reduces the frequency, rate or extent of cell adhesion. http://purl.obolibrary.org/obo/GO_0042051 compound eye photoreceptor development http://purl.obolibrary.org/obo/GO_0042462 eye photoreceptor cell development The process whose specific outcome is the progression of a light-responsive receptor in the compound eye over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0007163 establishment or maintenance of cell polarity http://purl.obolibrary.org/obo/GO_0009987 cellular process Any cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns. http://purl.obolibrary.org/obo/GO_0042053 regulation of dopamine metabolic process http://purl.obolibrary.org/obo/GO_0042069 regulation of catecholamine metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving dopamine. http://purl.obolibrary.org/obo/GO_0007204 positive regulation of cytosolic calcium ion concentration http://purl.obolibrary.org/obo/GO_0065008 regulation of biological quality Any process that increases the concentration of calcium ions in the cytosol. http://purl.obolibrary.org/obo/GO_0042065 glial cell growth http://purl.obolibrary.org/obo/GO_0048588 developmental cell growth Growth of glial cells, non-neuronal cells that provide support and nutrition, maintain homeostasis, form myelin, and participate in signal transmission in the nervous system. http://purl.obolibrary.org/obo/GO_0007210 serotonin receptor signaling pathway http://purl.obolibrary.org/obo/GO_0007165 signal transduction The series of molecular signals generated as a consequence of a serotonin receptor binding to one of its physiological ligands. http://purl.obolibrary.org/obo/GO_0042069 regulation of catecholamine metabolic process http://purl.obolibrary.org/obo/GO_0080090 regulation of primary metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving catecholamines. http://purl.obolibrary.org/obo/GO_0007213 G protein-coupled acetylcholine receptor signaling pathway http://purl.obolibrary.org/obo/GO_0007186 G protein-coupled receptor signaling pathway A G protein-coupled receptor signaling pathway initiated by a ligand binding to an acetylcholine receptor on the surface of a target cell, and ends with regulation of a downstream cellular process, e.g. transcription. http://purl.obolibrary.org/obo/GO_0042073 intraciliary transport http://purl.obolibrary.org/obo/GO_0010970 transport along microtubule The bidirectional movement of large protein complexes along microtubules within a cilium, mediated by motor proteins. http://purl.obolibrary.org/obo/GO_0007214 gamma-aminobutyric acid signaling pathway http://purl.obolibrary.org/obo/GO_0007267 cell-cell signaling The series of molecular signals generated by the binding of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms, to its receptor on the surface of a target cell. http://purl.obolibrary.org/obo/GO_0042078 germ-line stem cell division http://purl.obolibrary.org/obo/GO_0017145 stem cell division The self-renewing division of a germline stem cell to produce a daughter stem cell and a daughter germ cell, which will divide to form the gametes. http://purl.obolibrary.org/obo/GO_0007215 glutamate receptor signaling pathway http://purl.obolibrary.org/obo/GO_0007166 cell surface receptor signaling pathway The series of molecular signals initiated by the binding of glutamate to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. http://purl.obolibrary.org/obo/GO_0042101 T cell receptor complex http://purl.obolibrary.org/obo/GO_0098802 plasma membrane signaling receptor complex A protein complex that contains a disulfide-linked heterodimer of T cell receptor (TCR) chains, which are members of the immunoglobulin superfamily, and mediates antigen recognition, ultimately resulting in T cell activation. The TCR heterodimer is associated with the CD3 complex, which consists of the nonpolymorphic polypeptides gamma, delta, epsilon, zeta, and, in some cases, eta (an RNA splice variant of zeta) or Fc epsilon chains. http://purl.obolibrary.org/obo/GO_0007216 G protein-coupled glutamate receptor signaling pathway http://purl.obolibrary.org/obo/GO_0007186 G protein-coupled receptor signaling pathway A G protein-coupled receptor signaling pathway initiated by glutamate binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process. http://purl.obolibrary.org/obo/GO_0042103 positive regulation of T cell homeostatic proliferation http://purl.obolibrary.org/obo/GO_0046013 regulation of T cell homeostatic proliferation Any process that activates or increases the rate or extent of resting T cell proliferation. http://purl.obolibrary.org/obo/GO_0007218 neuropeptide signaling pathway http://purl.obolibrary.org/obo/GO_0007186 G protein-coupled receptor signaling pathway A G protein-coupled receptor signaling pathway initiated by a neuropeptide binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process. http://purl.obolibrary.org/obo/GO_0042105 alpha-beta T cell receptor complex http://purl.obolibrary.org/obo/GO_0042101 T cell receptor complex A T cell receptor complex in which the TCR heterodimer comprises alpha and beta chains, associated with the CD3 complex; recognizes a complex consisting of an antigen-derived peptide bound to a class I or class II MHC protein. http://purl.obolibrary.org/obo/GO_0042106 gamma-delta T cell receptor complex http://purl.obolibrary.org/obo/GO_0042101 T cell receptor complex A T cell receptor complex in which the TCR heterodimer comprises gamma and delta chains, associated with the CD3 complex; recognizes antigen directly, without a requirement for processing and presentation by an MHC protein. http://purl.obolibrary.org/obo/GO_0007268 chemical synaptic transmission http://purl.obolibrary.org/obo/GO_0098916 anterograde trans-synaptic signaling The vesicular release of classical neurotransmitter molecules from a presynapse, across a chemical synapse, the subsequent activation of neurotransmitter receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse. http://purl.obolibrary.org/obo/GO_0042151 nematocyst http://purl.obolibrary.org/obo/GO_0043232 intracellular membraneless organelle An organelle found in cnidoblast (nematoblast) cells. When matured, these stinging organelles store toxins and can deliver them when the cnidocil (a short extension of the cnidocyst) is stimulated by a prey or another stimulus. http://purl.obolibrary.org/obo/GO_0007272 ensheathment of neurons http://purl.obolibrary.org/obo/GO_0009987 cellular process The process in which glial cells envelop neuronal cell bodies and/or axons to form an insulating layer. This can take the form of myelinating or non-myelinating ensheathment. http://purl.obolibrary.org/obo/GO_0042157 lipoprotein metabolic process http://purl.obolibrary.org/obo/GO_0019538 protein metabolic process The chemical reactions and pathways involving any conjugated, water-soluble protein in which the covalently attached nonprotein group consists of a lipid or lipids. http://purl.obolibrary.org/obo/GO_0007274 neuromuscular synaptic transmission http://purl.obolibrary.org/obo/GO_0007268 chemical synaptic transmission The process of synaptic transmission from a neuron to a muscle, across a synapse. http://purl.obolibrary.org/obo/GO_0042173 regulation of sporulation resulting in formation of a cellular spore http://purl.obolibrary.org/obo/GO_0043937 regulation of sporulation Any process that modulates the frequency, rate or extent of spore formation. http://purl.obolibrary.org/obo/GO_0007276 gamete generation http://purl.obolibrary.org/obo/GO_0048609 multicellular organismal reproductive process The generation and maintenance of gametes in a multicellular organism. A gamete is a haploid reproductive cell. http://purl.obolibrary.org/obo/GO_0042174 negative regulation of sporulation resulting in formation of a cellular spore http://purl.obolibrary.org/obo/GO_0043939 negative regulation of sporulation Any process that stops, prevents, or reduces the frequency, rate or extent of sporulation. http://purl.obolibrary.org/obo/GO_0007277 pole cell development http://purl.obolibrary.org/obo/GO_0048468 cell development The process whose specific outcome is the progression of the pole cell over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0007279 pole cell formation http://purl.obolibrary.org/obo/GO_0003006 developmental process involved in reproduction Formation of a small group of cells (pole cells) at the posterior pole of the insect blastula. They are the first cells to cellularize after the arrival of nuclei at the end of the syncytial blastula stage and are the precursors to the insect germ cells. http://purl.obolibrary.org/obo/GO_0042176 regulation of protein catabolic process http://purl.obolibrary.org/obo/GO_0009894 regulation of catabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds. http://purl.obolibrary.org/obo/GO_0007281 germ cell development http://purl.obolibrary.org/obo/GO_0048468 cell development The process whose specific outcome is the progression of an immature germ cell over time, from its formation to the mature structure (gamete). A germ cell is any reproductive cell in a multicellular organism. http://purl.obolibrary.org/obo/GO_0042177 negative regulation of protein catabolic process http://purl.obolibrary.org/obo/GO_0009895 negative regulation of catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of protein catabolic process. http://purl.obolibrary.org/obo/GO_0007282 cystoblast division http://purl.obolibrary.org/obo/GO_0008356 asymmetric cell division Any of the rounds of incomplete mitosis undergone by a cystoblast to form a cyst of interconnected cells. http://purl.obolibrary.org/obo/GO_0042301 phosphate ion binding http://purl.obolibrary.org/obo/GO_0043168 anion binding Binding to a phosphate ion. http://purl.obolibrary.org/obo/GO_0007283 spermatogenesis http://purl.obolibrary.org/obo/GO_0003006 developmental process involved in reproduction The developmental process by which male germ line stem cells self renew or give rise to successive cell types resulting in the development of a spermatozoa. http://purl.obolibrary.org/obo/GO_0042304 regulation of fatty acid biosynthetic process http://purl.obolibrary.org/obo/GO_0046890 regulation of lipid biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. http://purl.obolibrary.org/obo/GO_0007284 spermatogonial cell division http://purl.obolibrary.org/obo/GO_0051301 cell division The mitotic divisions of the primary spermatogonial cell (a primordial male germ cell) to form secondary spermatogonia (primary spermatocytes). http://purl.obolibrary.org/obo/GO_0042387 plasmatocyte differentiation http://purl.obolibrary.org/obo/GO_0042386 hemocyte differentiation The process in which a hemocyte precursor cell acquires the characteristics of the phagocytic blood-cell type, the plasmatocyte. Plasmatocytes are a class of arthropod hemocytes important in the cellular defense response. http://purl.obolibrary.org/obo/GO_0007285 primary spermatocyte growth http://purl.obolibrary.org/obo/GO_0048588 developmental cell growth The phase of growth and gene expression that male germ cells undergo as they enter the spermatocyte stage. The cells grow in volume and transcribe most of the gene products needed for the morphological events that follow meiosis. http://purl.obolibrary.org/obo/GO_0042414 epinephrine metabolic process http://purl.obolibrary.org/obo/GO_0006584 catecholamine metabolic process The chemical reactions and pathways involving epinephrine, a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine. http://purl.obolibrary.org/obo/GO_0007288 sperm axoneme assembly http://purl.obolibrary.org/obo/GO_0003006 developmental process involved in reproduction The assembly and organization of the sperm flagellar axoneme, the bundle of microtubules and associated proteins that forms the core of the eukaryotic sperm flagellum, and is responsible for movement. http://purl.obolibrary.org/obo/GO_0042415 norepinephrine metabolic process http://purl.obolibrary.org/obo/GO_0006584 catecholamine metabolic process The chemical reactions and pathways involving norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine. http://purl.obolibrary.org/obo/GO_0007289 spermatid nucleus differentiation http://purl.obolibrary.org/obo/GO_0006997 nucleus organization The specialization of the spermatid nucleus during the development of a spermatid into a mature male gamete competent for fertilization. http://purl.obolibrary.org/obo/GO_0042417 dopamine metabolic process http://purl.obolibrary.org/obo/GO_0006584 catecholamine metabolic process The chemical reactions and pathways involving dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline. http://purl.obolibrary.org/obo/GO_0007292 female gamete generation http://purl.obolibrary.org/obo/GO_0007276 gamete generation Generation of the female gamete; specialised haploid cells produced by meiosis and along with a male gamete takes part in sexual reproduction. http://purl.obolibrary.org/obo/GO_0042418 epinephrine biosynthetic process http://purl.obolibrary.org/obo/GO_0042423 catecholamine biosynthetic process The chemical reactions and pathways resulting in the formation of epinephrine, a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine. http://purl.obolibrary.org/obo/GO_0007293 germarium-derived egg chamber formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis Construction of a stage-1 egg chamber in the anterior part of the germarium, from the progeny of germ-line and somatic stem cells. An example of this is found in Drosophila melanogaster. http://purl.obolibrary.org/obo/GO_0042420 dopamine catabolic process http://purl.obolibrary.org/obo/GO_0042424 catecholamine catabolic process The chemical reactions and pathways resulting in the breakdown of dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline. http://purl.obolibrary.org/obo/GO_0042421 norepinephrine biosynthetic process http://purl.obolibrary.org/obo/GO_0042423 catecholamine biosynthetic process The chemical reactions and pathways resulting in the formation of norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine. http://purl.obolibrary.org/obo/GO_0042422 norepinephrine catabolic process http://purl.obolibrary.org/obo/GO_0042424 catecholamine catabolic process The chemical reactions and pathways resulting in the breakdown of norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine. http://purl.obolibrary.org/obo/GO_0042423 catecholamine biosynthetic process http://purl.obolibrary.org/obo/GO_0009713 catechol-containing compound biosynthetic process The chemical reactions and pathways resulting in the formation of any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine. http://purl.obolibrary.org/obo/GO_0042424 catecholamine catabolic process http://purl.obolibrary.org/obo/GO_0019614 catechol-containing compound catabolic process The chemical reactions and pathways resulting in the breakdown of any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine. http://purl.obolibrary.org/obo/GO_0042428 serotonin metabolic process http://purl.obolibrary.org/obo/GO_0042430 indole-containing compound metabolic process The chemical reactions and pathways involving serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties. http://purl.obolibrary.org/obo/GO_0042429 serotonin catabolic process http://purl.obolibrary.org/obo/GO_0042436 indole-containing compound catabolic process The chemical reactions and pathways resulting in the breakdown of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties. http://purl.obolibrary.org/obo/GO_0042436 indole-containing compound catabolic process http://purl.obolibrary.org/obo/GO_0009056 catabolic process The chemical reactions and pathways resulting in the breakdown of compounds that contain an indole (2,3-benzopyrrole) skeleton. http://purl.obolibrary.org/obo/GO_0042442 melatonin catabolic process http://purl.obolibrary.org/obo/GO_0042436 indole-containing compound catabolic process The chemical reactions and pathways resulting in the breakdown of melatonin (N-acetyl-5-methoxytryptamine). http://purl.obolibrary.org/obo/GO_0042462 eye photoreceptor cell development http://purl.obolibrary.org/obo/GO_0042461 photoreceptor cell development Development of a photoreceptor, a sensory cell in the eye that reacts to the presence of light. They usually contain a pigment that undergoes a chemical change when light is absorbed, thus stimulating a nerve. http://purl.obolibrary.org/obo/GO_0042471 ear morphogenesis http://purl.obolibrary.org/obo/GO_0090596 sensory organ morphogenesis The process in which the anatomical structures of the ear are generated and organized. The ear is the sense organ in vertebrates that is specialized for the detection of sound, and the maintenance of balance. Includes the outer ear and middle ear, which collect and transmit sound waves; and the inner ear, which contains the organs of balance and (except in fish) hearing. Also includes the pinna, the visible part of the outer ear, present in some mammals. http://purl.obolibrary.org/obo/GO_0042473 outer ear morphogenesis http://purl.obolibrary.org/obo/GO_0048598 embryonic morphogenesis The process in which the anatomical structures of the outer ear are generated and organized. The outer ear is the part of the ear external to the tympanum (eardrum). It consists of a tube (the external auditory meatus) that directs sound waves on to the tympanum, and may also include the external pinna, which extends beyond the skull. http://purl.obolibrary.org/obo/GO_0042474 middle ear morphogenesis http://purl.obolibrary.org/obo/GO_0048598 embryonic morphogenesis The process in which the anatomical structures of the middle ear are generated and organized. The middle ear is the air-filled cavity within the skull of vertebrates that lies between the outer ear and the inner ear. It is linked to the pharynx (and therefore to outside air) via the Eustachian tube and in mammals contains the three ear ossicles, which transmit auditory vibrations from the outer ear (via the tympanum) to the inner ear (via the oval window). http://purl.obolibrary.org/obo/GO_0042475 odontogenesis of dentin-containing tooth http://purl.obolibrary.org/obo/GO_0042476 odontogenesis The process whose specific outcome is the progression of a dentin-containing tooth over time, from its formation to the mature structure. A dentin-containing tooth is a hard, bony organ borne on the jaw or other bone of a vertebrate, and is composed mainly of dentin, a dense calcified substance, covered by a layer of enamel. http://purl.obolibrary.org/obo/GO_0042476 odontogenesis http://purl.obolibrary.org/obo/GO_0009887 animal organ morphogenesis The process whose specific outcome is the progression of a tooth or teeth over time, from formation to the mature structure(s). A tooth is any hard bony, calcareous, or chitinous organ found in the mouth or pharynx of an animal and used in procuring or masticating food. http://purl.obolibrary.org/obo/GO_0042478 regulation of eye photoreceptor cell development http://purl.obolibrary.org/obo/GO_0060284 regulation of cell development Any process that modulates the frequency, rate or extent of eye photoreceptor development. http://purl.obolibrary.org/obo/GO_0042479 positive regulation of eye photoreceptor cell development http://purl.obolibrary.org/obo/GO_0010720 positive regulation of cell development Any process that activates or increases the frequency, rate or extent of eye photoreceptor development. http://purl.obolibrary.org/obo/GO_0042480 negative regulation of eye photoreceptor cell development http://purl.obolibrary.org/obo/GO_0010721 negative regulation of cell development Any process that stops, prevents, or reduces the frequency, rate or extent of eye photoreceptor development. http://purl.obolibrary.org/obo/GO_0007297 follicle cell of egg chamber migration http://purl.obolibrary.org/obo/GO_0010631 epithelial cell migration The directed movement of an ovarian follicle cell that takes place during oogenesis. During egg chamber formation, follicle cells migrate to envelop the germ-line cysts and move in between cysts. At stage 10B, follicle cells migrate centripetally between the nurse cells and the oocyte, enclosing the anterior of the egg. An example of this is found in Drosophila melanogaster. http://purl.obolibrary.org/obo/GO_0042481 regulation of odontogenesis http://purl.obolibrary.org/obo/GO_2000027 regulation of animal organ morphogenesis Any process that modulates the frequency, rate or extent of the formation and development of a tooth or teeth. http://purl.obolibrary.org/obo/GO_0007298 border follicle cell migration http://purl.obolibrary.org/obo/GO_0007297 follicle cell of egg chamber migration The directed movement of a border cell through the nurse cells to reach the oocyte. An example of this is found in Drosophila melanogaster. http://purl.obolibrary.org/obo/GO_0042482 positive regulation of odontogenesis http://purl.obolibrary.org/obo/GO_0042481 regulation of odontogenesis Any process that activates or increases the frequency, rate or extent of the formation and development of a tooth or teeth. http://purl.obolibrary.org/obo/GO_0007308 oocyte construction http://purl.obolibrary.org/obo/GO_0048469 cell maturation The synthesis, deposition, and organization of the materials in a cell of an ovary; where the cell can then undergo meiosis and form an ovum. An example of this is found in Drosophila melanogaster. http://purl.obolibrary.org/obo/GO_0007309 oocyte axis specification http://purl.obolibrary.org/obo/GO_0009798 axis specification The establishment, maintenance and elaboration of an axis in the oocyte. An example of this is found in Drosophila melanogaster. http://purl.obolibrary.org/obo/GO_0042483 negative regulation of odontogenesis http://purl.obolibrary.org/obo/GO_0042481 regulation of odontogenesis Any process that stops, prevents, or reduces the frequency, rate or extent of the formation and development of a tooth or teeth. http://purl.obolibrary.org/obo/GO_0007314 oocyte anterior/posterior axis specification http://purl.obolibrary.org/obo/GO_0009948 anterior/posterior axis specification Polarization of the oocyte along its anterior-posterior axis. An example of this is found in Drosophila melanogaster. http://purl.obolibrary.org/obo/GO_0042487 regulation of odontogenesis of dentin-containing tooth http://purl.obolibrary.org/obo/GO_0042481 regulation of odontogenesis Any process that modulates the frequency, rate or extent of the formation and development of teeth, the hard, bony appendages which are borne on the jaws, or on other bones in the walls of the mouth or pharynx of most vertebrates. http://purl.obolibrary.org/obo/GO_0007320 insemination http://purl.obolibrary.org/obo/GO_0044703 multi-organism reproductive process The introduction of semen or sperm into the genital tract of a female. http://purl.obolibrary.org/obo/GO_0042488 positive regulation of odontogenesis of dentin-containing tooth http://purl.obolibrary.org/obo/GO_0042487 regulation of odontogenesis of dentin-containing tooth Any process that activates or increases the frequency, rate or extent of the formation and development of teeth, the hard, bony appendages that are borne on the jaws, or on other bones in the walls of the mouth or pharynx of most vertebrates. http://purl.obolibrary.org/obo/GO_0007338 single fertilization http://purl.obolibrary.org/obo/GO_0009566 fertilization The union of male and female gametes to form a zygote. http://purl.obolibrary.org/obo/GO_0042489 negative regulation of odontogenesis of dentin-containing tooth http://purl.obolibrary.org/obo/GO_0042487 regulation of odontogenesis of dentin-containing tooth Any process that stops, prevents, or reduces the frequency, rate or extent of the formation and development of teeth, the hard, bony appendages which are borne on the jaws, or on other bones in the walls of the mouth or pharynx. http://purl.obolibrary.org/obo/GO_0007343 egg activation http://purl.obolibrary.org/obo/GO_0001775 cell activation The process in which the egg becomes metabolically active, initiates protein and DNA synthesis and undergoes structural changes to its cortex and/or cytoplasm. http://purl.obolibrary.org/obo/GO_0042490 mechanoreceptor differentiation http://purl.obolibrary.org/obo/GO_0030182 neuron differentiation The process in which a relatively unspecialized cell acquires specialized features of a mechanoreceptor, a cell specialized to transduce mechanical stimuli and relay that information centrally in the nervous system. http://purl.obolibrary.org/obo/GO_0007346 regulation of mitotic cell cycle http://purl.obolibrary.org/obo/GO_0051726 regulation of cell cycle Any process that modulates the rate or extent of progress through the mitotic cell cycle. http://purl.obolibrary.org/obo/GO_0042571 immunoglobulin complex, circulating http://purl.obolibrary.org/obo/GO_0019814 immunoglobulin complex An immunoglobulin complex that is secreted into extracellular space and found in mucosal areas or other tissues or circulating in the blood or lymph. In its canonical form, a circulating immunoglobulin complex is composed of two identical heavy chains and two identical light chains, held together by disulfide bonds. Some forms of are polymers of the basic structure and contain additional components such as J-chain and the secretory component. http://purl.obolibrary.org/obo/GO_0007349 cellularization http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The separation of a multi-nucleate cell or syncytium into individual cells. An example of this is found in Drosophila melanogaster embryo development. http://purl.obolibrary.org/obo/GO_0042582 azurophil granule http://purl.obolibrary.org/obo/GO_0030141 secretory granule Primary lysosomal granule readily stainable with a Romanowsky stain. http://purl.obolibrary.org/obo/GO_0007350 blastoderm segmentation http://purl.obolibrary.org/obo/GO_0035282 segmentation The hierarchical steps resulting in the progressive subdivision of the anterior/posterior axis of the embryo. http://purl.obolibrary.org/obo/GO_0042585 germinal vesicle http://purl.obolibrary.org/obo/GO_0001674 female germ cell nucleus The enlarged, fluid filled nucleus of a primary oocyte, the development of which is suspended in prophase I of the first meiotic division between embryohood and sexual maturity. http://purl.obolibrary.org/obo/GO_0007351 tripartite regional subdivision http://purl.obolibrary.org/obo/GO_0003002 regionalization Subdivision of the embryo along the anterior/posterior axis into anterior, posterior and terminal regions. http://purl.obolibrary.org/obo/GO_0042588 zymogen granule http://purl.obolibrary.org/obo/GO_0030141 secretory granule A membrane-bounded, cytoplasmic secretory granule found in enzyme-secreting cells and visible by light microscopy. Contain zymogen, an inactive enzyme precursor, often of a digestive enzyme. http://purl.obolibrary.org/obo/GO_0007354 zygotic determination of anterior/posterior axis, embryo http://purl.obolibrary.org/obo/GO_0008595 anterior/posterior axis specification, embryo The specification of the anterior/posterior axis of the embryo by products of genes expressed in the zygote; exemplified in insects by the gap genes, pair rule genes and segment polarity gene cascade. http://purl.obolibrary.org/obo/GO_0042589 zymogen granule membrane http://purl.obolibrary.org/obo/GO_0030667 secretory granule membrane The lipid bilayer surrounding a zymogen granule. http://purl.obolibrary.org/obo/GO_0007378 amnioserosa formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis Formation of the amnioserosa, an epithelium that occupies a hole in the embryonic dorsal epidermis. This occurs by the transformation of a narrow strip of cells at the dorsal midline of the blastoderm from columnar to squamous cells, accompanied by a lateral shift. http://purl.obolibrary.org/obo/GO_0042599 lamellar body http://purl.obolibrary.org/obo/GO_0030141 secretory granule A membrane-bounded organelle, specialized for the storage and secretion of various substances (surfactant phospholipids, glycoproteins and acid phosphates) which are arranged in the form of tightly packed, concentric, membrane sheets or lamellae. Has some similar properties to, but is distinct from, a lysosome. http://purl.obolibrary.org/obo/GO_0007399 nervous system development http://purl.obolibrary.org/obo/GO_0048731 system development The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state. http://purl.obolibrary.org/obo/GO_0042608 T cell receptor binding http://purl.obolibrary.org/obo/GO_0044877 protein-containing complex binding Binding to a T cell receptor, the antigen-recognizing receptor on the surface of T cells. http://purl.obolibrary.org/obo/GO_0007406 negative regulation of neuroblast proliferation http://purl.obolibrary.org/obo/GO_1902692 regulation of neuroblast proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of the proliferation of neuroblasts. http://purl.obolibrary.org/obo/GO_0042613 MHC class II protein complex http://purl.obolibrary.org/obo/GO_0042611 MHC protein complex A transmembrane protein complex composed of an MHC class II alpha and MHC class II beta chain, and with or without a bound peptide or polysaccharide antigen. http://purl.obolibrary.org/obo/GO_0007407 neuroblast activation http://purl.obolibrary.org/obo/GO_0001775 cell activation A change in the morphology or behavior of a neuroblast resulting from exposure to an activating factor such as a cellular or soluble ligand. http://purl.obolibrary.org/obo/GO_0042629 mast cell granule http://purl.obolibrary.org/obo/GO_0005764 lysosome Coarse, bluish-black staining cytoplasmic granules, bounded by a plasma membrane and found in mast cells and basophils. Contents include histamine, heparin, chondroitin sulfates, chymase and tryptase. http://purl.obolibrary.org/obo/GO_0007409 axonogenesis http://purl.obolibrary.org/obo/GO_0048812 neuron projection morphogenesis De novo generation of a long process of a neuron, including the terminal branched region. Refers to the morphogenesis or creation of shape or form of the developing axon, which carries efferent (outgoing) action potentials from the cell body towards target cells. http://purl.obolibrary.org/obo/GO_0042634 regulation of hair cycle http://purl.obolibrary.org/obo/GO_0051239 regulation of multicellular organismal process Any process that modulates the frequency, rate or extent of the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair. http://purl.obolibrary.org/obo/GO_0007416 synapse assembly http://purl.obolibrary.org/obo/GO_0050808 synapse organization The aggregation, arrangement and bonding together of a set of components to form a synapse. This process ends when the synapse is mature (functional). http://purl.obolibrary.org/obo/GO_0042635 positive regulation of hair cycle http://purl.obolibrary.org/obo/GO_0042634 regulation of hair cycle Any process that activates or increases the frequency, rate or extent of the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair. http://purl.obolibrary.org/obo/GO_0007417 central nervous system development http://purl.obolibrary.org/obo/GO_0048731 system development The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord. http://purl.obolibrary.org/obo/GO_0042636 negative regulation of hair cycle http://purl.obolibrary.org/obo/GO_0042634 regulation of hair cycle Any process that stops, prevents, or reduces the frequency, rate or extent of the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair. http://purl.obolibrary.org/obo/GO_0007418 ventral midline development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the ventral midline over time, from its formation to the mature structure. In protostomes (such as insects, snails and worms) as well as deuterostomes (vertebrates), the midline is an embryonic region that functions in patterning of the adjacent nervous tissue. The ventral midline in insects is a cell population extending along the ventral surface of the embryo and is the region from which cells detach to form the ventrally located nerve cords. In vertebrates, the midline is originally located dorsally. During development, it folds inwards and becomes the ventral part of the dorsally located neural tube and is then called the ventral midline, or floor plate. http://purl.obolibrary.org/obo/GO_0042644 chloroplast nucleoid http://purl.obolibrary.org/obo/GO_0042646 plastid nucleoid The region of a chloroplast to which the DNA is confined. http://purl.obolibrary.org/obo/GO_0007420 brain development http://purl.obolibrary.org/obo/GO_0048513 animal organ development The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.). http://purl.obolibrary.org/obo/GO_0042648 chloroplast chromosome http://purl.obolibrary.org/obo/GO_0009508 plastid chromosome A circular DNA molecule containing chloroplast encoded genes. http://purl.obolibrary.org/obo/GO_0007422 peripheral nervous system development http://purl.obolibrary.org/obo/GO_0048731 system development The process whose specific outcome is the progression of the peripheral nervous system over time, from its formation to the mature structure. The peripheral nervous system is one of the two major divisions of the nervous system. Nerves in the PNS connect the central nervous system (CNS) with sensory organs, other organs, muscles, blood vessels and glands. http://purl.obolibrary.org/obo/GO_0042670 retinal cone cell differentiation http://purl.obolibrary.org/obo/GO_0060219 camera-type eye photoreceptor cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a retinal cone cell. http://purl.obolibrary.org/obo/GO_0007424 open tracheal system development http://purl.obolibrary.org/obo/GO_0060541 respiratory system development The process whose specific outcome is the progression of an open tracheal system over time, from its formation to the mature structure. An open tracheal system is a respiratory system, a branched network of epithelial tubes that supplies oxygen to target tissues via spiracles. An example of this is found in Drosophila melanogaster. http://purl.obolibrary.org/obo/GO_0042675 compound eye cone cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a compound eye cone cell, a cone-shaped cell, that focuses light in a compound eye. http://purl.obolibrary.org/obo/GO_0007431 salivary gland development http://purl.obolibrary.org/obo/GO_0048732 gland development The process whose specific outcome is the progression of the salivary gland over time, from its formation to the mature structure. Salivary glands include any of the saliva-secreting exocrine glands of the oral cavity. http://purl.obolibrary.org/obo/GO_0042688 crystal cell differentiation http://purl.obolibrary.org/obo/GO_0042386 hemocyte differentiation The process in which a hemocyte precursor cell acquires the characteristics of a crystal cell, a class of cells that contain crystalline inclusions and are involved in the melanization of pathogenic material in the hemolymph. http://purl.obolibrary.org/obo/GO_0007435 salivary gland morphogenesis http://purl.obolibrary.org/obo/GO_0022612 gland morphogenesis The process in which the anatomical structures of the salivary gland are generated and organized. http://purl.obolibrary.org/obo/GO_0042689 regulation of crystal cell differentiation http://purl.obolibrary.org/obo/GO_0045610 regulation of hemocyte differentiation Any process that modulates the frequency, rate or extent of crystal cell differentiation. http://purl.obolibrary.org/obo/GO_0007438 oenocyte development http://purl.obolibrary.org/obo/GO_0048468 cell development The process whose specific outcome is the progression of the oenocyte over time, from its formation to the mature structure. The oenocytes are large secretory cells found in clusters underlying the epidermis of larval abdominal segments. http://purl.obolibrary.org/obo/GO_0042690 negative regulation of crystal cell differentiation http://purl.obolibrary.org/obo/GO_0045611 negative regulation of hemocyte differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of crystal cell differentiation. http://purl.obolibrary.org/obo/GO_0007439 ectodermal digestive tract development http://purl.obolibrary.org/obo/GO_0048729 tissue morphogenesis The process whose specific outcome is the progression of the ectodermal digestive tract over time, from its formation to the mature structure. The ectodermal digestive tract includes those portions that are derived from ectoderm. http://purl.obolibrary.org/obo/GO_0042691 positive regulation of crystal cell differentiation http://purl.obolibrary.org/obo/GO_0045612 positive regulation of hemocyte differentiation Any process that activates or increases the frequency, rate or extent of crystal cell differentiation. http://purl.obolibrary.org/obo/GO_0007440 foregut morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structures of the foregut are generated and organized. http://purl.obolibrary.org/obo/GO_0042692 muscle cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a muscle cell. http://purl.obolibrary.org/obo/GO_0007442 hindgut morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structures of the hindgut are generated and organized. http://purl.obolibrary.org/obo/GO_0042701 progesterone secretion http://purl.obolibrary.org/obo/GO_0035929 steroid hormone secretion The regulated release of progesterone, a steroid hormone, by the corpus luteum of the ovary and by the placenta. http://purl.obolibrary.org/obo/GO_0007443 Malpighian tubule morphogenesis http://purl.obolibrary.org/obo/GO_0048598 embryonic morphogenesis The process in which the anatomical structures of the Malpighian tubule are generated and organized. This process takes place entirely during the embryonic phase. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which leads into the posterior part of the gut. http://purl.obolibrary.org/obo/GO_0042702 uterine wall growth http://purl.obolibrary.org/obo/GO_0048589 developmental growth The regrowth of the endometrium and blood vessels in the uterus following menstruation, resulting from a rise in progesterone levels. http://purl.obolibrary.org/obo/GO_0007444 imaginal disc development http://purl.obolibrary.org/obo/GO_0048513 animal organ development The process whose specific outcome is the progression of the imaginal disc over time, from its formation to the metamorphosis to form adult structures. Imaginal discs are epithelial infoldings in the larvae of holometabolous insects that develop into adult structures (legs, antennae, wings, etc.). http://purl.obolibrary.org/obo/GO_0042713 sperm ejaculation http://purl.obolibrary.org/obo/GO_0048609 multicellular organismal reproductive process The expulsion of seminal fluid, thick white fluid containing spermatozoa, from the male genital tract. http://purl.obolibrary.org/obo/GO_0007446 imaginal disc growth http://purl.obolibrary.org/obo/GO_0048589 developmental growth The increase in mass of imaginal discs by cell proliferation prior to metamorphosis. Imaginal discs are epithelial infoldings in the larvae of holometabolous insects that develop into adult structures (legs, antennae, wings, etc.) during metamorphosis from larval to adult form. http://purl.obolibrary.org/obo/GO_0042953 lipoprotein transport http://purl.obolibrary.org/obo/GO_0044872 lipoprotein localization The directed movement of any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0007488 histoblast morphogenesis http://purl.obolibrary.org/obo/GO_0000902 cell morphogenesis The process in which the anatomical structures derived from the histoblast disc are generated and organized. This includes the transformation of histoblast cells into adult structures during pupal metamorphosis. Histoblast cells are cells founded in the embryo that are the progenitors to the adult abdomen. http://purl.obolibrary.org/obo/GO_0042996 regulation of Golgi to plasma membrane protein transport http://purl.obolibrary.org/obo/GO_0060627 regulation of vesicle-mediated transport Any process that modulates the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane. http://purl.obolibrary.org/obo/GO_0007494 midgut development http://purl.obolibrary.org/obo/GO_0048565 digestive tract development The process whose specific outcome is the progression of the midgut over time, from its formation to the mature structure. The midgut is the middle part of the alimentary canal from the stomach, or entrance of the bile duct, to, or including, the large intestine. http://purl.obolibrary.org/obo/GO_0042997 negative regulation of Golgi to plasma membrane protein transport http://purl.obolibrary.org/obo/GO_1903077 negative regulation of protein localization to plasma membrane Any process that stops, prevents, or reduces the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane. http://purl.obolibrary.org/obo/GO_0007498 mesoderm development http://purl.obolibrary.org/obo/GO_0009888 tissue development The process whose specific outcome is the progression of the mesoderm over time, from its formation to the mature structure. The mesoderm is the middle germ layer that develops into muscle, bone, cartilage, blood and connective tissue. http://purl.obolibrary.org/obo/GO_0042998 positive regulation of Golgi to plasma membrane protein transport http://purl.obolibrary.org/obo/GO_1903078 positive regulation of protein localization to plasma membrane Any process that activates or increases the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane. http://purl.obolibrary.org/obo/GO_0007506 gonadal mesoderm development http://purl.obolibrary.org/obo/GO_0060485 mesenchyme development The process whose specific outcome is the progression of the gonadal mesoderm over time, from its formation to the mature structure. The gonadal mesoderm is the middle layer of the three primary germ layers of the embryo which will go on to form the gonads of the organism. http://purl.obolibrary.org/obo/GO_0043001 Golgi to plasma membrane protein transport http://purl.obolibrary.org/obo/GO_0072659 protein localization to plasma membrane The directed movement of proteins from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane. Golgi to plasma membrane transport precedes exocytosis. http://purl.obolibrary.org/obo/GO_0007516 hemocyte development http://purl.obolibrary.org/obo/GO_0030097 hemopoiesis The process whose specific outcome is the progression of the hemocyte over time, from its formation to the mature structure. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. http://purl.obolibrary.org/obo/GO_0043030 regulation of macrophage activation http://purl.obolibrary.org/obo/GO_0002694 regulation of leukocyte activation Any process that modulates the frequency or rate of macrophage activation. http://purl.obolibrary.org/obo/GO_0007517 muscle organ development http://purl.obolibrary.org/obo/GO_0048513 animal organ development The process whose specific outcome is the progression of the muscle over time, from its formation to the mature structure. The muscle is an organ consisting of a tissue made up of various elongated cells that are specialized to contract and thus to produce movement and mechanical work. http://purl.obolibrary.org/obo/GO_0043031 negative regulation of macrophage activation http://purl.obolibrary.org/obo/GO_0043030 regulation of macrophage activation Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage activation. http://purl.obolibrary.org/obo/GO_0007528 neuromuscular junction development http://purl.obolibrary.org/obo/GO_0050808 synapse organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuromuscular junction. http://purl.obolibrary.org/obo/GO_0043032 positive regulation of macrophage activation http://purl.obolibrary.org/obo/GO_0043030 regulation of macrophage activation Any process that stimulates, induces or increases the rate of macrophage activation. http://purl.obolibrary.org/obo/GO_0007530 sex determination http://purl.obolibrary.org/obo/GO_0003006 developmental process involved in reproduction Any process that establishes and transmits the specification of sexual status of an individual organism. http://purl.obolibrary.org/obo/GO_0043038 amino acid activation http://purl.obolibrary.org/obo/GO_0006520 amino acid metabolic process The modification of an amino acid to an active form, for incorporation into a peptide, protein or other macromolecule. http://purl.obolibrary.org/obo/GO_0007548 sex differentiation http://purl.obolibrary.org/obo/GO_0003006 developmental process involved in reproduction The establishment of the sex of an organism by physical differentiation. http://purl.obolibrary.org/obo/GO_0043049 otic placode formation http://purl.obolibrary.org/obo/GO_0060788 ectodermal placode formation The initial developmental process that will lead to the formation of the vertebrate inner ear. The otic placode forms as a thickening of the head ectoderm adjacent to the developing hindbrain. http://purl.obolibrary.org/obo/GO_0007552 metamorphosis http://purl.obolibrary.org/obo/GO_0007275 multicellular organism development A biological process in which an animal physically develops after birth or hatching, involving a conspicuous and relatively abrupt change in the animal's form or structure. Examples include the change from tadpole to frog, and the change from larva to adult. An example of this is found in Drosophila melanogaster. http://purl.obolibrary.org/obo/GO_0007553 regulation of ecdysteroid metabolic process http://purl.obolibrary.org/obo/GO_0032350 regulation of hormone metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving ecdysteroids, a group of polyhydroxylated ketosteroids which initiate post-embryonic development, including the metamorphosis of immature forms and the development of the reproductive system and the maturation of oocytes in adult females. http://purl.obolibrary.org/obo/GO_0007554 regulation of ecdysteroid biosynthetic process http://purl.obolibrary.org/obo/GO_0090030 regulation of steroid hormone biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ecdysteroids. http://purl.obolibrary.org/obo/GO_0007555 regulation of ecdysteroid secretion http://purl.obolibrary.org/obo/GO_2000831 regulation of steroid hormone secretion Any process that modulates the frequency, rate or extent of the regulated release of ecdysteroid from a cell. http://purl.obolibrary.org/obo/GO_0007557 regulation of juvenile hormone biosynthetic process http://purl.obolibrary.org/obo/GO_0046890 regulation of lipid biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of juvenile hormone. http://purl.obolibrary.org/obo/GO_0007558 regulation of juvenile hormone secretion http://purl.obolibrary.org/obo/GO_0046883 regulation of hormone secretion Any process that modulates the frequency, rate or extent of juvenile hormone secretion. http://purl.obolibrary.org/obo/GO_0043116 negative regulation of vascular permeability http://purl.obolibrary.org/obo/GO_0043114 regulation of vascular permeability Any process that reduces the extent to which blood vessels can be pervaded by fluid. http://purl.obolibrary.org/obo/GO_0007560 imaginal disc morphogenesis http://purl.obolibrary.org/obo/GO_0009887 animal organ morphogenesis The process in which the anatomical structures derived from an imaginal disc are generated and organized. The imaginal discs are epithelial infoldings in the larvae of holometabolous insects that develop into adult appendages (legs, antennae, wings, etc.) during metamorphosis from larval to adult form. http://purl.obolibrary.org/obo/GO_0043117 positive regulation of vascular permeability http://purl.obolibrary.org/obo/GO_0043114 regulation of vascular permeability Any process that increases the extent to which blood vessels can be pervaded by fluid. http://purl.obolibrary.org/obo/GO_0007565 female pregnancy http://purl.obolibrary.org/obo/GO_0044703 multi-organism reproductive process The set of physiological processes that allow an embryo or foetus to develop within the body of a female animal. It covers the time from fertilization of a female ovum by a male spermatozoon until birth. http://purl.obolibrary.org/obo/GO_0043129 surfactant homeostasis http://purl.obolibrary.org/obo/GO_0140962 multicellular organismal-level chemical homeostasis Any process involved in the maintenance of a steady-state level of a surface-active agent that maintains the surface tension of a liquid. http://purl.obolibrary.org/obo/GO_0007566 embryo implantation http://purl.obolibrary.org/obo/GO_0022414 reproductive process Attachment of the blastocyst to the uterine lining. http://purl.obolibrary.org/obo/GO_0043133 hindgut contraction http://purl.obolibrary.org/obo/GO_0022600 digestive system process A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the hindgut. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The hindgut is the posterior part of the alimentary canal, including the rectum, and the large intestine. http://purl.obolibrary.org/obo/GO_0007586 digestion http://purl.obolibrary.org/obo/GO_0032501 multicellular organismal process The whole of the physical, chemical, and biochemical processes carried out by multicellular organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism. http://purl.obolibrary.org/obo/GO_0043134 regulation of hindgut contraction http://purl.obolibrary.org/obo/GO_0044058 regulation of digestive system process Any process that modulates the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine. http://purl.obolibrary.org/obo/GO_0007588 excretion http://purl.obolibrary.org/obo/GO_0003008 system process The elimination by an organism of the waste products that arise as a result of metabolic activity. These products include water, carbon dioxide (CO2), and nitrogenous compounds. http://purl.obolibrary.org/obo/GO_0043143 regulation of translation by machinery localization http://purl.obolibrary.org/obo/GO_0008104 intracellular protein localization Any process in which proteins and protein complexes involved in translation are transported to, or maintained in, a specific location. http://purl.obolibrary.org/obo/GO_0007589 body fluid secretion http://purl.obolibrary.org/obo/GO_0050878 regulation of body fluid levels The controlled release of a fluid by a cell or tissue in an animal. http://purl.obolibrary.org/obo/GO_0043158 heterocyst development http://purl.obolibrary.org/obo/GO_0048869 cellular developmental process The cellular developmental process by which a cell becomes a heterocyst, a cell that carries out nitrogen fixation. This process involves changes to the cell wall, expression of nitrogenase and other proteins involved in nitrogen fixation, and degradation of photosystem II, which produces oxygen. This process is known to occur in some cyanobacteria. http://purl.obolibrary.org/obo/GO_0007595 lactation http://purl.obolibrary.org/obo/GO_0007589 body fluid secretion The regulated release of milk from the mammary glands and the period of time that a mother lactates to feed her young. http://purl.obolibrary.org/obo/GO_0043167 ion binding http://purl.obolibrary.org/obo/GO_0036094 small molecule binding Binding to an ion, a charged atoms or groups of atoms. http://purl.obolibrary.org/obo/GO_0007596 blood coagulation http://purl.obolibrary.org/obo/GO_0050817 coagulation The sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot; it may be divided into three stages: stage 1, the formation of intrinsic and extrinsic prothrombin converting principle; stage 2, the formation of thrombin; stage 3, the formation of stable fibrin polymers. http://purl.obolibrary.org/obo/GO_0043184 vascular endothelial growth factor receptor 2 binding http://purl.obolibrary.org/obo/GO_0005172 vascular endothelial growth factor receptor binding Binding to a vascular endothelial growth factor receptor 2. http://purl.obolibrary.org/obo/GO_0007599 hemostasis http://purl.obolibrary.org/obo/GO_0050878 regulation of body fluid levels The stopping of bleeding (loss of body fluid) or the arrest of the circulation to an organ or part. http://purl.obolibrary.org/obo/GO_0043195 terminal bouton http://purl.obolibrary.org/obo/GO_0098793 presynapse Terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters. The axon terminus is considered to be the whole region of thickening and the terminal bouton is a specialized region of it. http://purl.obolibrary.org/obo/GO_0007600 sensory perception http://purl.obolibrary.org/obo/GO_0050877 nervous system process The series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. http://purl.obolibrary.org/obo/GO_0043208 glycosphingolipid binding http://purl.obolibrary.org/obo/GO_0046625 sphingolipid binding Binding to glycosphingolipid, a compound with residues of sphingoid and at least one monosaccharide. http://purl.obolibrary.org/obo/GO_0007601 visual perception http://purl.obolibrary.org/obo/GO_0050953 sensory perception of light stimulus The series of events required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual stimuli are detected in the form of photons and are processed to form an image. http://purl.obolibrary.org/obo/GO_0043209 myelin sheath http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure An electrically insulating fatty layer that surrounds the axons of many neurons. It is an outgrowth of glial cells: Schwann cells supply the myelin for peripheral neurons while oligodendrocytes supply it to those of the central nervous system. http://purl.obolibrary.org/obo/GO_0007605 sensory perception of sound http://purl.obolibrary.org/obo/GO_0050954 sensory perception of mechanical stimulus The series of events required for an organism to receive an auditory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Sonic stimuli are detected in the form of vibrations and are processed to form a sound. http://purl.obolibrary.org/obo/GO_0043229 intracellular organelle http://purl.obolibrary.org/obo/GO_0043226 organelle Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane. http://purl.obolibrary.org/obo/GO_0007606 sensory perception of chemical stimulus http://purl.obolibrary.org/obo/GO_0007600 sensory perception The series of events required for an organism to receive a sensory chemical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. http://purl.obolibrary.org/obo/GO_0043230 extracellular organelle http://purl.obolibrary.org/obo/GO_0043226 organelle Organized structure of distinctive morphology and function, occurring outside the cell. Includes, for example, extracellular membrane vesicles (EMVs) and the cellulosomes of anaerobic bacteria and fungi. http://purl.obolibrary.org/obo/GO_0007608 sensory perception of smell http://purl.obolibrary.org/obo/GO_0007606 sensory perception of chemical stimulus The series of events required for an organism to receive an olfactory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Olfaction involves the detection of chemical composition of an organism's ambient medium by chemoreceptors. This is a neurological process. http://purl.obolibrary.org/obo/GO_0043242 negative regulation of protein-containing complex disassembly http://purl.obolibrary.org/obo/GO_0051129 negative regulation of cellular component organization Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components. http://purl.obolibrary.org/obo/GO_0007611 learning or memory http://purl.obolibrary.org/obo/GO_0007610 behavior The acquisition and processing of information and/or the storage and retrieval of this information over time. http://purl.obolibrary.org/obo/GO_0043243 positive regulation of protein-containing complex disassembly http://purl.obolibrary.org/obo/GO_0051130 positive regulation of cellular component organization Any process that activates or increases the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components. http://purl.obolibrary.org/obo/GO_0007612 learning http://purl.obolibrary.org/obo/GO_0007611 learning or memory Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs as the result of experience. http://purl.obolibrary.org/obo/GO_0043249 erythrocyte maturation http://purl.obolibrary.org/obo/GO_0048469 cell maturation A developmental process, independent of morphogenetic (shape) change, that is required for an erythrocyte to attain its fully functional state. http://purl.obolibrary.org/obo/GO_0007613 memory http://purl.obolibrary.org/obo/GO_0007611 learning or memory The activities involved in the mental information processing system that receives (registers), modifies, stores, and retrieves informational stimuli. The main stages involved in the formation and retrieval of memory are encoding (processing of received information by acquisition), storage (building a permanent record of received information as a result of consolidation) and retrieval (calling back the stored information and use it in a suitable way to execute a given task). http://purl.obolibrary.org/obo/GO_0043264 extracellular membraneless organelle http://purl.obolibrary.org/obo/GO_0043228 membraneless organelle Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring outside the cell. http://purl.obolibrary.org/obo/GO_0007617 mating behavior http://purl.obolibrary.org/obo/GO_0019098 reproductive behavior The behavioral interactions between organisms for the purpose of mating, or sexual reproduction resulting in the formation of zygotes. http://purl.obolibrary.org/obo/GO_0043266 regulation of potassium ion transport http://purl.obolibrary.org/obo/GO_0010959 regulation of metal ion transport Any process that modulates the frequency, rate or extent of the directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0007620 copulation http://purl.obolibrary.org/obo/GO_0007617 mating behavior The act of sexual union between male and female, involving the transfer of sperm. http://purl.obolibrary.org/obo/GO_0043267 negative regulation of potassium ion transport http://purl.obolibrary.org/obo/GO_0043271 negative regulation of monoatomic ion transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0007626 locomotory behavior http://purl.obolibrary.org/obo/GO_0007610 behavior The specific movement from place to place of an organism in response to external or internal stimuli. Locomotion of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions. http://purl.obolibrary.org/obo/GO_0043268 positive regulation of potassium ion transport http://purl.obolibrary.org/obo/GO_0043270 positive regulation of monoatomic ion transport Any process that activates or increases the frequency, rate or extent of the directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0007635 chemosensory behavior http://purl.obolibrary.org/obo/GO_0007610 behavior Behavior that is dependent upon the sensation of chemicals. http://purl.obolibrary.org/obo/GO_0043277 apoptotic cell clearance http://purl.obolibrary.org/obo/GO_0006909 phagocytosis The recognition and removal of an apoptotic cell by a neighboring cell or by a phagocyte. http://purl.obolibrary.org/obo/GO_0008015 blood circulation http://purl.obolibrary.org/obo/GO_0003013 circulatory system process The flow of blood through the body of an animal, enabling the transport of nutrients to the tissues and the removal of waste products. http://purl.obolibrary.org/obo/GO_0043282 chordate pharyngeal muscle development http://purl.obolibrary.org/obo/GO_0007517 muscle organ development The process whose specific outcome is the progression of the pharyngeal muscle over time, from its formation to the mature structure. A pharyngeal muscle is any muscle that forms part of the pharynx. http://purl.obolibrary.org/obo/GO_0008017 microtubule binding http://purl.obolibrary.org/obo/GO_0015631 tubulin binding Binding to a microtubule, a filament composed of tubulin monomers. http://purl.obolibrary.org/obo/GO_0043300 regulation of leukocyte degranulation http://purl.obolibrary.org/obo/GO_1903305 regulation of regulated secretory pathway Any process that modulates the frequency, rate, or extent of leukocyte degranulation. http://purl.obolibrary.org/obo/GO_0008028 monocarboxylic acid transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0046943 carboxylic acid transmembrane transporter activity Enables the transfer of monocarboxylic acids from one side of a membrane to the other. A monocarboxylic acid is an organic acid with one COOH group. http://purl.obolibrary.org/obo/GO_0043301 negative regulation of leukocyte degranulation http://purl.obolibrary.org/obo/GO_1903306 negative regulation of regulated secretory pathway Any process that stops, prevents, or reduces the rate of leukocyte degranulation. http://purl.obolibrary.org/obo/GO_0008053 mitochondrial fusion http://purl.obolibrary.org/obo/GO_0048284 organelle fusion Merging of two or more mitochondria within a cell to form a single compartment. http://purl.obolibrary.org/obo/GO_0043302 positive regulation of leukocyte degranulation http://purl.obolibrary.org/obo/GO_1903307 positive regulation of regulated secretory pathway Any process that activates or increases the frequency, rate or extent of leukocyte degranulation. http://purl.obolibrary.org/obo/GO_0008066 glutamate receptor activity http://purl.obolibrary.org/obo/GO_0004888 transmembrane signaling receptor activity Combining with glutamate and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. http://purl.obolibrary.org/obo/GO_0043304 regulation of mast cell degranulation http://purl.obolibrary.org/obo/GO_0043300 regulation of leukocyte degranulation Any process that modulates the frequency, rate, or extent of mast cell degranulation. http://purl.obolibrary.org/obo/GO_0008076 voltage-gated potassium channel complex http://purl.obolibrary.org/obo/GO_0098797 plasma membrane protein complex A protein complex that forms a transmembrane channel through which potassium ions may cross a cell membrane in response to changes in membrane potential. http://purl.obolibrary.org/obo/GO_0043305 negative regulation of mast cell degranulation http://purl.obolibrary.org/obo/GO_0043304 regulation of mast cell degranulation Any process that stops, prevents, or reduces the rate of mast cell degranulation. http://purl.obolibrary.org/obo/GO_0008078 mesodermal cell migration http://purl.obolibrary.org/obo/GO_0001667 ameboidal-type cell migration The orderly movement of mesodermal cells from one site to another. http://purl.obolibrary.org/obo/GO_0043306 positive regulation of mast cell degranulation http://purl.obolibrary.org/obo/GO_0043304 regulation of mast cell degranulation Any process that activates or increases the frequency, rate or extent of mast cell degranulation. http://purl.obolibrary.org/obo/GO_0008088 axo-dendritic transport http://purl.obolibrary.org/obo/GO_0010970 transport along microtubule The directed movement of organelles or molecules along microtubules in neuron projections. http://purl.obolibrary.org/obo/GO_0043308 eosinophil degranulation http://purl.obolibrary.org/obo/GO_0043299 leukocyte degranulation The regulated exocytosis of secretory granules containing preformed mediators such as major basic protein, eosinophil peroxidase, and eosinophil cationic protein by an eosinophil. http://purl.obolibrary.org/obo/GO_0008089 anterograde axonal transport http://purl.obolibrary.org/obo/GO_0098930 axonal transport The directed movement of organelles or molecules along microtubules from the cell body toward the cell periphery in nerve cell axons. http://purl.obolibrary.org/obo/GO_0043309 regulation of eosinophil degranulation http://purl.obolibrary.org/obo/GO_0043300 regulation of leukocyte degranulation Any process that modulates the frequency, rate, or extent of eosinophil degranulation. http://purl.obolibrary.org/obo/GO_0008090 retrograde axonal transport http://purl.obolibrary.org/obo/GO_0098930 axonal transport The directed movement of organelles or molecules along microtubules from the cell periphery toward the cell body in nerve cell axons. http://purl.obolibrary.org/obo/GO_0043310 negative regulation of eosinophil degranulation http://purl.obolibrary.org/obo/GO_0043309 regulation of eosinophil degranulation Any process that stops, prevents, or reduces the rate of eosinophil degranulation. http://purl.obolibrary.org/obo/GO_0008104 intracellular protein localization http://purl.obolibrary.org/obo/GO_0033036 macromolecule localization Any process in which a protein is transported to, or maintained in, a specific location. http://purl.obolibrary.org/obo/GO_0043311 positive regulation of eosinophil degranulation http://purl.obolibrary.org/obo/GO_0043309 regulation of eosinophil degranulation Any process that activates or increases the frequency, rate or extent of eosinophil degranulation. http://purl.obolibrary.org/obo/GO_0008152 metabolic process http://purl.obolibrary.org/obo/GO_0009987 cellular process A cellular process consisting of the biochemical pathways by which a living organism transforms chemical substances. This includes including anabolism (biosynthetic process) and catabolism (catabolic process). Metabolic processes includes the transformation of small molecules, as well macromolecular processes such as DNA repair and replication, protein synthesis and degradation. http://purl.obolibrary.org/obo/GO_0043312 neutrophil degranulation http://purl.obolibrary.org/obo/GO_0043299 leukocyte degranulation The regulated exocytosis of secretory granules containing preformed mediators such as proteases, lipases, and inflammatory mediators by a neutrophil. http://purl.obolibrary.org/obo/GO_0008202 steroid metabolic process http://purl.obolibrary.org/obo/GO_0006629 lipid metabolic process The chemical reactions and pathways involving steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus. http://purl.obolibrary.org/obo/GO_0043313 regulation of neutrophil degranulation http://purl.obolibrary.org/obo/GO_0043300 regulation of leukocyte degranulation Any process that modulates the frequency, rate, or extent of neutrophil degranulation. http://purl.obolibrary.org/obo/GO_0008207 C21-steroid hormone metabolic process http://purl.obolibrary.org/obo/GO_0042445 hormone metabolic process The chemical reactions and pathways involving C21-steroid hormones, steroid compounds containing 21 carbons which function as hormones. http://purl.obolibrary.org/obo/GO_0043314 negative regulation of neutrophil degranulation http://purl.obolibrary.org/obo/GO_0043313 regulation of neutrophil degranulation Any process that stops, prevents, or reduces the rate of neutrophil degranulation. http://purl.obolibrary.org/obo/GO_0008208 C21-steroid hormone catabolic process http://purl.obolibrary.org/obo/GO_0042447 hormone catabolic process The chemical reactions and pathways resulting in the breakdown of C21-steroid hormones, steroid compounds containing 21 carbons which function as hormones. http://purl.obolibrary.org/obo/GO_0043315 positive regulation of neutrophil degranulation http://purl.obolibrary.org/obo/GO_0043313 regulation of neutrophil degranulation Any process that activates or increases the frequency, rate or extent of neutrophil degranulation. http://purl.obolibrary.org/obo/GO_0008211 glucocorticoid metabolic process http://purl.obolibrary.org/obo/GO_0008202 steroid metabolic process The chemical reactions and pathways involving glucocorticoids, hormonal C21 corticosteroids synthesized from cholesterol. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects. http://purl.obolibrary.org/obo/GO_0043316 cytotoxic T cell degranulation http://purl.obolibrary.org/obo/GO_0043299 leukocyte degranulation The regulated exocytosis of secretory granules containing preformed mediators such as perforin and granzymes by a cytotoxic T cell. http://purl.obolibrary.org/obo/GO_0008212 mineralocorticoid metabolic process http://purl.obolibrary.org/obo/GO_0042445 hormone metabolic process The chemical reactions and pathways involving mineralocorticoids, hormonal C21 corticosteroids synthesized from cholesterol. Mineralocorticoids act primarily on water and electrolyte balance. http://purl.obolibrary.org/obo/GO_0043317 regulation of cytotoxic T cell degranulation http://purl.obolibrary.org/obo/GO_0043300 regulation of leukocyte degranulation Any process that modulates the frequency, rate, or extent of cytotoxic T cell degranulation. http://purl.obolibrary.org/obo/GO_0043318 negative regulation of cytotoxic T cell degranulation http://purl.obolibrary.org/obo/GO_0043317 regulation of cytotoxic T cell degranulation Any process that stops, prevents, or reduces the rate of cytotoxic T cell degranulation. http://purl.obolibrary.org/obo/GO_0008291 acetylcholine metabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process The chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues. http://purl.obolibrary.org/obo/GO_0043319 positive regulation of cytotoxic T cell degranulation http://purl.obolibrary.org/obo/GO_0043317 regulation of cytotoxic T cell degranulation Any process that activates or increases the frequency, rate or extent of cytotoxic T cell degranulation. http://purl.obolibrary.org/obo/GO_0008354 germ cell migration http://purl.obolibrary.org/obo/GO_0016477 cell migration The orderly movement of a cell specialized to produce haploid gametes through the embryo from its site of production to the place where the gonads will form. http://purl.obolibrary.org/obo/GO_0043320 natural killer cell degranulation http://purl.obolibrary.org/obo/GO_0043299 leukocyte degranulation The regulated exocytosis of secretory granules containing preformed mediators such as perforin and granzymes by a natural killer cell. http://purl.obolibrary.org/obo/GO_0008356 asymmetric cell division http://purl.obolibrary.org/obo/GO_0051301 cell division The asymmetric division of cells to produce two daughter cells with different developmental potentials. It is of fundamental significance for the generation of cell diversity. http://purl.obolibrary.org/obo/GO_0043321 regulation of natural killer cell degranulation http://purl.obolibrary.org/obo/GO_0043300 regulation of leukocyte degranulation Any process that modulates the frequency, rate, or extent of natural killer cell degranulation. http://purl.obolibrary.org/obo/GO_0008358 maternal determination of anterior/posterior axis, embryo http://purl.obolibrary.org/obo/GO_0008595 anterior/posterior axis specification, embryo The specification of the anterior/posterior axis of the embryo by gradients of maternally-transcribed gene products; exemplified in insects by the morphogens, bicoid and nanos. http://purl.obolibrary.org/obo/GO_0043322 negative regulation of natural killer cell degranulation http://purl.obolibrary.org/obo/GO_0043321 regulation of natural killer cell degranulation Any process that stops, prevents, or reduces the rate of natural killer cell degranulation. http://purl.obolibrary.org/obo/GO_0008361 regulation of cell size http://purl.obolibrary.org/obo/GO_0032535 regulation of cellular component size Any process that modulates the size of a cell. http://purl.obolibrary.org/obo/GO_0043323 positive regulation of natural killer cell degranulation http://purl.obolibrary.org/obo/GO_0043321 regulation of natural killer cell degranulation Any process that activates or increases the frequency, rate or extent of natural killer cell degranulation. http://purl.obolibrary.org/obo/GO_0008406 gonad development http://purl.obolibrary.org/obo/GO_0048608 reproductive structure development The process whose specific outcome is the progression of the gonad over time, from its formation to the mature structure. The gonad is an animal organ that produces gametes; in some species it also produces hormones. http://purl.obolibrary.org/obo/GO_0043324 pigment metabolic process involved in developmental pigmentation http://purl.obolibrary.org/obo/GO_0043474 pigment metabolic process involved in pigmentation The chemical reactions and pathways involving biological pigments e.g. melanin, occurring as part of the development of an organ or organism. http://purl.obolibrary.org/obo/GO_0008504 monoamine transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022804 active transmembrane transporter activity Enables the transfer of monoamines, organic compounds that contain one amino group that is connected to an aromatic ring by an ethylene group (-CH2-CH2-), from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0043353 enucleate erythrocyte differentiation http://purl.obolibrary.org/obo/GO_0030218 erythrocyte differentiation The process in which a myeloid precursor cell acquires specialized features of an erythrocyte without a nucleus. An example of this process is found in Mus musculus. http://purl.obolibrary.org/obo/GO_0008595 anterior/posterior axis specification, embryo http://purl.obolibrary.org/obo/GO_0000578 embryonic axis specification The specification of the anterior/posterior axis of the embryo by the products of genes expressed maternally and genes expressed in the zygote. http://purl.obolibrary.org/obo/GO_0043354 enucleate erythrocyte maturation http://purl.obolibrary.org/obo/GO_0043249 erythrocyte maturation A developmental process, independent of morphogenetic (shape) change, that is required for an enucleate erythrocyte to attain its fully functional state. An enucleate erythrocyte is an erythrocyte without a nucleus. http://purl.obolibrary.org/obo/GO_0008610 lipid biosynthetic process http://purl.obolibrary.org/obo/GO_0009058 biosynthetic process The chemical reactions and pathways resulting in the formation of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. http://purl.obolibrary.org/obo/GO_0043362 nucleate erythrocyte maturation http://purl.obolibrary.org/obo/GO_0043249 erythrocyte maturation A developmental process, independent of morphogenetic (shape) change, that is required for a nucleate erythrocyte to attain its fully functional state. A nucleate erythrocyte is an erythrocyte with a nucleus. http://purl.obolibrary.org/obo/GO_0008643 carbohydrate transport http://purl.obolibrary.org/obo/GO_0006810 transport The directed movement of carbohydrate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carbohydrates are a group of organic compounds based of the general formula Cx(H2O)y. http://purl.obolibrary.org/obo/GO_0043363 nucleate erythrocyte differentiation http://purl.obolibrary.org/obo/GO_0030218 erythrocyte differentiation The process in which a myeloid precursor cell acquires specializes features of an erythrocyte with a nucleus, as found in non-mammalian vertebrates such as birds. http://purl.obolibrary.org/obo/GO_0043368 positive T cell selection http://purl.obolibrary.org/obo/GO_0045058 T cell selection The process of sparing immature T cells which react with self-MHC protein complexes with low affinity levels from apoptotic death. http://purl.obolibrary.org/obo/GO_0009070 serine family amino acid biosynthetic process http://purl.obolibrary.org/obo/GO_1901607 alpha-amino acid biosynthetic process The chemical reactions and pathways resulting in the formation of amino acids of the serine family, comprising cysteine, glycine, homoserine, selenocysteine and serine. http://purl.obolibrary.org/obo/GO_0043376 regulation of CD8-positive, alpha-beta T cell differentiation http://purl.obolibrary.org/obo/GO_2001185 regulation of CD8-positive, alpha-beta T cell activation Any process that modulates the frequency, rate, or extent of CD8-positive, alpha-beta T cell differentiation. http://purl.obolibrary.org/obo/GO_0009072 aromatic amino acid metabolic process http://purl.obolibrary.org/obo/GO_0006520 amino acid metabolic process The chemical reactions and pathways involving aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan). http://purl.obolibrary.org/obo/GO_0043377 negative regulation of CD8-positive, alpha-beta T cell differentiation http://purl.obolibrary.org/obo/GO_2001186 negative regulation of CD8-positive, alpha-beta T cell activation Any process that stops, prevents, or reduces the rate of CD8-positive, alpha-beta T cell differentiation. http://purl.obolibrary.org/obo/GO_0009084 L-glutamine family amino acid biosynthetic process http://purl.obolibrary.org/obo/GO_0170038 proteinogenic amino acid biosynthetic process The chemical reactions and pathways resulting in the formation of amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline. http://purl.obolibrary.org/obo/GO_0043378 positive regulation of CD8-positive, alpha-beta T cell differentiation http://purl.obolibrary.org/obo/GO_2001187 positive regulation of CD8-positive, alpha-beta T cell activation Any process that activates or increases the frequency, rate or extent of CD8-positive, alpha-beta T cell differentiation. http://purl.obolibrary.org/obo/GO_0009100 glycoprotein metabolic process http://purl.obolibrary.org/obo/GO_1901135 carbohydrate derivative metabolic process The chemical reactions and pathways involving glycoproteins, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide. http://purl.obolibrary.org/obo/GO_0043379 memory T cell differentiation http://purl.obolibrary.org/obo/GO_0090715 immunological memory formation process The process in which a newly activated T cell acquires specialized features of a memory T cell. http://purl.obolibrary.org/obo/GO_0009101 glycoprotein biosynthetic process http://purl.obolibrary.org/obo/GO_0009059 macromolecule biosynthetic process The chemical reactions and pathways resulting in the formation of glycoproteins, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide. http://purl.obolibrary.org/obo/GO_0043380 regulation of memory T cell differentiation http://purl.obolibrary.org/obo/GO_0045580 regulation of T cell differentiation Any process that modulates the frequency, rate, or extent of memory T cell differentiation. http://purl.obolibrary.org/obo/GO_0009117 nucleotide metabolic process http://purl.obolibrary.org/obo/GO_0006753 nucleoside phosphate metabolic process The chemical reactions and pathways involving a nucleotide, a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic nucleotides (nucleoside cyclic phosphates). http://purl.obolibrary.org/obo/GO_0043381 negative regulation of memory T cell differentiation http://purl.obolibrary.org/obo/GO_0043380 regulation of memory T cell differentiation Any process that stops, prevents, or reduces the rate of memory T cell differentiation. http://purl.obolibrary.org/obo/GO_0009132 nucleoside diphosphate metabolic process http://purl.obolibrary.org/obo/GO_0006753 nucleoside phosphate metabolic process The chemical reactions and pathways involving a nucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with diphosphate on the sugar. http://purl.obolibrary.org/obo/GO_0043382 positive regulation of memory T cell differentiation http://purl.obolibrary.org/obo/GO_0043380 regulation of memory T cell differentiation Any process that activates or increases the frequency, rate or extent of memory T cell differentiation. http://purl.obolibrary.org/obo/GO_0009152 purine ribonucleotide biosynthetic process http://purl.obolibrary.org/obo/GO_0009260 ribonucleotide biosynthetic process The chemical reactions and pathways resulting in the formation of a purine ribonucleotide, a compound consisting of ribonucleoside (a purine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. http://purl.obolibrary.org/obo/GO_0043384 pre-T cell receptor complex http://purl.obolibrary.org/obo/GO_0098802 plasma membrane signaling receptor complex A receptor complex found on immature T cells consisting of a T cell receptor beta chain and the pre-TCR-alpha chain, along with additional signaling components including CD3 family members and additional signaling proteins. http://purl.obolibrary.org/obo/UBERON_0035006 preputial swelling of female http://purl.obolibrary.org/obo/UBERON_0035004 preputial swelling http://purl.obolibrary.org/obo/GO_0043388 positive regulation of DNA binding http://purl.obolibrary.org/obo/GO_0051101 regulation of DNA binding Any process that increases the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid). http://purl.obolibrary.org/obo/NCBITaxon_2301119 Rhabditomorpha http://purl.obolibrary.org/obo/NCBITaxon_2301116 Rhabditina http://purl.obolibrary.org/obo/GO_0043392 negative regulation of DNA binding http://purl.obolibrary.org/obo/GO_0051101 regulation of DNA binding Any process that stops or reduces the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid). http://purl.obolibrary.org/obo/GO_0043394 proteoglycan binding http://purl.obolibrary.org/obo/GO_0097367 carbohydrate derivative binding Binding to a proteoglycan, any glycoprotein in which the carbohydrate units are glycosaminoglycans. http://purl.obolibrary.org/obo/PATO_0002062 physical quality of a process http://purl.obolibrary.org/obo/PATO_0001236 process quality http://purl.obolibrary.org/obo/GO_0043417 negative regulation of skeletal muscle tissue regeneration http://purl.obolibrary.org/obo/GO_0043416 regulation of skeletal muscle tissue regeneration Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle regeneration. http://purl.obolibrary.org/obo/UBERON_6000004 panarthropod head http://purl.obolibrary.org/obo/UBERON_0000033 head http://purl.obolibrary.org/obo/GO_0043474 pigment metabolic process involved in pigmentation http://purl.obolibrary.org/obo/GO_0042440 pigment metabolic process The chemical reactions and pathways involving a pigment, any general or particular coloring matter in living organisms, resulting in the deposition or aggregation of pigment in an organism, tissue or cell. http://purl.obolibrary.org/obo/UBERON_0036267 vulval vein http://purl.obolibrary.org/obo/UBERON_0001638 vein http://purl.obolibrary.org/obo/GO_0043523 regulation of neuron apoptotic process http://purl.obolibrary.org/obo/GO_0042981 regulation of apoptotic process Any process that modulates the occurrence or rate of cell death by apoptotic process in neurons. http://purl.obolibrary.org/obo/UBERON_0035546 uveal vein http://purl.obolibrary.org/obo/UBERON_0001638 vein http://purl.obolibrary.org/obo/GO_0043524 negative regulation of neuron apoptotic process http://purl.obolibrary.org/obo/GO_0043523 regulation of neuron apoptotic process Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process in neurons. http://purl.obolibrary.org/obo/UBERON_0035662 parotid vein http://purl.obolibrary.org/obo/UBERON_0001638 vein http://purl.obolibrary.org/obo/GO_0043525 positive regulation of neuron apoptotic process http://purl.obolibrary.org/obo/GO_0043065 positive regulation of apoptotic process Any process that activates or increases the frequency, rate or extent of cell death of neurons by apoptotic process. https://purl.brain-bican.org/ontology/mbao/MBA_953 Pineal body https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions http://purl.obolibrary.org/obo/GO_0043535 regulation of blood vessel endothelial cell migration http://purl.obolibrary.org/obo/GO_0010594 regulation of endothelial cell migration Any process that modulates the frequency, rate or extent of the migration of the endothelial cells of blood vessels. https://purl.brain-bican.org/ontology/mbao/MBA_645 Vermal regions https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions http://purl.obolibrary.org/obo/GO_0043536 positive regulation of blood vessel endothelial cell migration http://purl.obolibrary.org/obo/GO_0010595 positive regulation of endothelial cell migration Any process that activates or increases the frequency, rate or extent of the migration of the endothelial cells of blood vessels. http://purl.obolibrary.org/obo/UBERON_0035237 branch of internal carotid artery http://purl.obolibrary.org/obo/UBERON_0005396 carotid artery segment http://purl.obolibrary.org/obo/GO_0043537 negative regulation of blood vessel endothelial cell migration http://purl.obolibrary.org/obo/GO_0010596 negative regulation of endothelial cell migration Any process that stops, prevents, or reduces the frequency, rate or extent of the migration of the endothelial cells of blood vessels. http://purl.obolibrary.org/obo/IAO_0000027 data entity http://purl.obolibrary.org/obo/IAO_0000030 information content entity http://purl.obolibrary.org/obo/GO_0043576 regulation of respiratory gaseous exchange http://purl.obolibrary.org/obo/GO_0051239 regulation of multicellular organismal process Any process that modulates the frequency, rate or extent of the process of gaseous exchange between an organism and its environment. http://purl.obolibrary.org/obo/CL_0000445 apoptosis fated cell http://purl.obolibrary.org/obo/CL_0000000 cell http://purl.obolibrary.org/obo/GO_0043583 ear development http://purl.obolibrary.org/obo/GO_0007423 sensory organ development The process whose specific outcome is the progression of the ear over time, from its formation to the mature structure. The ear is the sense organ in vertebrates that is specialized for the detection of sound, and the maintenance of balance. Includes the outer ear and middle ear, which collect and transmit sound waves; and the inner ear, which contains the organs of balance and (except in fish) hearing. Also includes the pinna, the visible part of the outer ear, present in some mammals. http://purl.obolibrary.org/obo/CL_0000520 prokaryotic cell http://purl.obolibrary.org/obo/CL_0000000 cell http://purl.obolibrary.org/obo/GO_0043585 nose morphogenesis http://purl.obolibrary.org/obo/GO_0090596 sensory organ morphogenesis The process in which the anatomical structures of the nose are generated and organized. The nose is the specialized structure of the face that serves as the organ of the sense of smell and as part of the respiratory system. Includes the nasi externus (external nose) and cavitas nasi (nasal cavity). http://purl.obolibrary.org/obo/CL_0000204 acceleration receptive cell http://purl.obolibrary.org/obo/CL_0000006 neuronal receptor cell http://purl.obolibrary.org/obo/GO_0043586 tongue development http://purl.obolibrary.org/obo/GO_0007423 sensory organ development The process whose specific outcome is the progression of the tongue over time, from its formation to the mature structure. The tongue is the movable, muscular organ on the floor of the mouth of most vertebrates, in many other mammals is the principal organ of taste, aids in the prehension of food, in swallowing, and in modifying the voice as in speech. http://purl.obolibrary.org/obo/CL_0000376 humidity receptor cell http://purl.obolibrary.org/obo/CL_0000006 neuronal receptor cell http://purl.obolibrary.org/obo/GO_0043587 tongue morphogenesis http://purl.obolibrary.org/obo/GO_0090596 sensory organ morphogenesis The process in which the anatomical structures of the tongue are generated and organized. The tongue is the movable, muscular organ on the floor of the mouth of most vertebrates, in man other mammals is the principal organ of taste, aids in the prehension of food, in swallowing, and in modifying the voice as in speech. http://purl.obolibrary.org/obo/CL_1000082 stretch receptor cell http://purl.obolibrary.org/obo/CL_0000006 neuronal receptor cell http://purl.obolibrary.org/obo/GO_0043589 skin morphogenesis http://purl.obolibrary.org/obo/GO_0009887 animal organ morphogenesis The process in which the anatomical structures of the skin are generated and organized. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner, sensitive and vascular dermis (cutis, corium or true skin) composed mostly of connective tissue. http://purl.obolibrary.org/obo/CL_0000356 hair matrix stem cell http://purl.obolibrary.org/obo/CL_0000035 single fate stem cell http://purl.obolibrary.org/obo/GO_0043679 axon terminus http://purl.obolibrary.org/obo/GO_0044306 neuron projection terminus Terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters. The axon terminus is considered to be the whole region of thickening and the terminal button is a specialized region of it. http://purl.obolibrary.org/obo/CL_0000357 stratified epithelial stem cell http://purl.obolibrary.org/obo/CL_0000036 epithelial fate stem cell http://purl.obolibrary.org/obo/GO_0043695 detection of pheromone http://purl.obolibrary.org/obo/GO_0019236 response to pheromone The series of events in which a pheromone stimulus is received by a cell and converted into a molecular signal. http://purl.obolibrary.org/obo/CL_0000354 blastemal cell http://purl.obolibrary.org/obo/CL_0000048 multi fate stem cell http://purl.obolibrary.org/obo/GO_0043931 ossification involved in bone maturation http://purl.obolibrary.org/obo/GO_0001503 ossification The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone, involved in the progression of the skeleton from its formation to its mature state. http://purl.obolibrary.org/obo/CL_0000069 branched duct epithelial cell http://purl.obolibrary.org/obo/CL_0000068 duct epithelial cell http://purl.obolibrary.org/obo/CL_0000072 non-branched duct epithelial cell http://purl.obolibrary.org/obo/CL_0002078 meso-epithelial cell http://purl.obolibrary.org/obo/GO_0043932 ossification involved in bone remodeling http://purl.obolibrary.org/obo/GO_0001503 ossification The formation or growth of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone, involved in response to injury or other physical, physiological or environmental stress stimuli. http://purl.obolibrary.org/obo/CL_0000377 tracheoblast http://purl.obolibrary.org/obo/CL_0000069 branched duct epithelial cell http://purl.obolibrary.org/obo/GO_0043937 regulation of sporulation http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of sporulation, the process whose specific outcome is the progression of a spore over time, from its initiation to the mature structure. http://purl.obolibrary.org/obo/CL_0000146 simple columnar epithelial cell http://purl.obolibrary.org/obo/CL_0000075 columnar/cuboidal epithelial cell http://purl.obolibrary.org/obo/GO_0043938 positive regulation of sporulation http://purl.obolibrary.org/obo/GO_0043937 regulation of sporulation Any process that activates, maintains or increases the frequency, rate or extent of sporulation, the process whose specific outcome is the progression of a spore over time, from its initiation to the mature structure. http://purl.obolibrary.org/obo/CL_0000618 sheath cell http://purl.obolibrary.org/obo/CL_0000075 columnar/cuboidal epithelial cell http://purl.obolibrary.org/obo/GO_0043939 negative regulation of sporulation http://purl.obolibrary.org/obo/GO_0043937 regulation of sporulation Any process that stops, prevents, or reduces the frequency, rate or extent of sporulation, the process whose specific outcome is the progression of a spore over time, from its initiation to the mature structure. http://purl.obolibrary.org/obo/CL_0000684 littoral cell of liver http://purl.obolibrary.org/obo/CL_0000077 mesothelial cell http://purl.obolibrary.org/obo/GO_0043940 regulation of sexual sporulation resulting in formation of a cellular spore http://purl.obolibrary.org/obo/GO_0042173 regulation of sporulation resulting in formation of a cellular spore Any process that modulates the frequency, rate or extent of the formation of cellular spores derived from the products of meiosis. http://purl.obolibrary.org/obo/CL_0000237 keratinizing barrier epithelial cell http://purl.obolibrary.org/obo/CL_0002077 ecto-epithelial cell http://purl.obolibrary.org/obo/GO_0043941 positive regulation of sexual sporulation resulting in formation of a cellular spore http://purl.obolibrary.org/obo/GO_0051446 positive regulation of meiotic cell cycle Any process that activates, maintains or increases the frequency, rate or extent of the formation of cellular spores derived from the products of meiosis. http://purl.obolibrary.org/obo/CL_0000390 blood cell (sensu Nematoda and Protostomia) http://purl.obolibrary.org/obo/CL_0000081 blood cell http://purl.obolibrary.org/obo/GO_0043942 negative regulation of sexual sporulation resulting in formation of a cellular spore http://purl.obolibrary.org/obo/GO_0051447 negative regulation of meiotic cell cycle Any process that stops, prevents, or reduces the frequency, rate or extent of the formation of cellular spores derived from the products of meiosis. http://purl.obolibrary.org/obo/CL_0000123 neuron associated cell (sensu Vertebrata) http://purl.obolibrary.org/obo/CL_0000095 neuron associated cell http://purl.obolibrary.org/obo/GO_0044058 regulation of digestive system process http://purl.obolibrary.org/obo/GO_0044057 regulation of system process Any process that modulates the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism. http://purl.obolibrary.org/obo/CL_0000130 neuron associated cell (sensu Nematoda and Protostomia) http://purl.obolibrary.org/obo/CL_0000095 neuron associated cell http://purl.obolibrary.org/obo/GO_0044062 regulation of excretion http://purl.obolibrary.org/obo/GO_0044057 regulation of system process Any process that modulates the frequency, rate, or extent of excretion, the elimination by an organism of the waste products that arise as a result of metabolic activity. http://purl.obolibrary.org/obo/CL_0000246 Mauthner neuron http://purl.obolibrary.org/obo/CL_0000099 interneuron http://purl.obolibrary.org/obo/GO_0044090 positive regulation of vacuole organization http://purl.obolibrary.org/obo/GO_0010638 positive regulation of organelle organization Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a vacuole. http://purl.obolibrary.org/obo/CL_0000406 CNS short range interneuron http://purl.obolibrary.org/obo/CL_0000099 interneuron http://purl.obolibrary.org/obo/GO_0044207 translation initiation ternary complex http://purl.obolibrary.org/obo/GO_1990904 ribonucleoprotein complex A ribonucleoprotein complex that contains aminoacylated initiator methionine tRNA, GTP, and initiation factor 2 (either eIF2 in eukaryotes, or IF2 in prokaryotes). In prokaryotes, fMet-tRNA (initiator) is used rather than Met-tRNA (initiator). http://purl.obolibrary.org/obo/CL_0000410 CNS long range interneuron http://purl.obolibrary.org/obo/CL_0000099 interneuron http://purl.obolibrary.org/obo/GO_0044258 intestinal lipid catabolic process http://purl.obolibrary.org/obo/GO_0016042 lipid catabolic process The chemical reactions and pathways resulting in the breakdown into fatty acids and monoglycerides of lipids in the small intestine. Lipids are broken down by lipases released by the pancreas. http://purl.obolibrary.org/obo/CL_0000251 extramedullary cell http://purl.obolibrary.org/obo/CL_0000101 sensory neuron http://purl.obolibrary.org/obo/GO_0044292 dendrite terminus http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure A structure at the distal end of a dendrite adapted to carry out a specific function, e.g. dendriole. http://purl.obolibrary.org/obo/CL_0000143 guidepost cell http://purl.obolibrary.org/obo/CL_0000130 neuron associated cell (sensu Nematoda and Protostomia) http://purl.obolibrary.org/obo/GO_0044293 dendriole http://purl.obolibrary.org/obo/GO_0044292 dendrite terminus Small dendrites that makes up a brush structure found as the terminal specialization of a dendrite of a unipolar brush cell (UBC). http://purl.obolibrary.org/obo/CL_0000324 metanephric mesenchyme stem cell http://purl.obolibrary.org/obo/CL_0000134 mesenchymal stem cell http://purl.obolibrary.org/obo/GO_0044297 cell body http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure The portion of a cell bearing surface projections such as axons, dendrites, cilia, or flagella that includes the nucleus, but excludes all cell projections. http://purl.obolibrary.org/obo/CL_0000383 nephrogenic mesenchyme stem cell http://purl.obolibrary.org/obo/CL_0011026 progenitor cell http://purl.obolibrary.org/obo/GO_0044306 neuron projection terminus http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure The specialized, terminal region of a neuron projection such as an axon or a dendrite. http://purl.obolibrary.org/obo/CL_0000149 visual pigment cell http://purl.obolibrary.org/obo/CL_0000147 pigment cell http://purl.obolibrary.org/obo/GO_0044316 cone cell pedicle http://purl.obolibrary.org/obo/GO_0043679 axon terminus A specialized axon terminus which is produced by retinal cone cells. Pedicles are large, conical, flat end-feet (8-10 micrometers diameter) of the retinal cone axon that lie more or less side by side on the same plane at the outer edge of the outer plexiform layer (OPL). http://purl.obolibrary.org/obo/CL_0000341 pigment cell (sensu Nematoda and Protostomia) http://purl.obolibrary.org/obo/CL_0000147 pigment cell http://purl.obolibrary.org/obo/GO_0044342 type B pancreatic cell proliferation http://purl.obolibrary.org/obo/GO_0050673 epithelial cell proliferation The multiplication or reproduction of pancreatic B cells, resulting in the expansion of an pancreatic B cell population. Pancreatic B cell are cells of the pancreas that secrete insulin. http://purl.obolibrary.org/obo/CL_0001658 visual pigment cell (sensu Nematoda and Protostomia) http://purl.obolibrary.org/obo/CL_0000341 pigment cell (sensu Nematoda and Protostomia) http://purl.obolibrary.org/obo/GO_0044346 fibroblast apoptotic process http://purl.obolibrary.org/obo/GO_0006915 apoptotic process Any apoptotic process in a fibroblast, a connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. http://purl.obolibrary.org/obo/CL_0000159 seromucus secreting cell http://purl.obolibrary.org/obo/CL_0000151 secretory cell http://purl.obolibrary.org/obo/GO_0044380 protein localization to cytoskeleton http://purl.obolibrary.org/obo/GO_0033365 protein localization to organelle A process in which a protein is transported to, or maintained in, a location within the cytoskeleton. http://purl.obolibrary.org/obo/CL_0000249 hatching gland cell http://purl.obolibrary.org/obo/CL_0000151 secretory cell http://purl.obolibrary.org/obo/GO_0044458 motile cilium assembly http://purl.obolibrary.org/obo/GO_0060271 cilium assembly The aggregation, arrangement and bonding together of a set of components to form a motile cilium. http://purl.obolibrary.org/obo/CL_0000314 milk secreting cell http://purl.obolibrary.org/obo/CL_0000151 secretory cell http://purl.obolibrary.org/obo/GO_0044565 dendritic cell proliferation http://purl.obolibrary.org/obo/GO_0032943 mononuclear cell proliferation The expansion of a dendritic cell population by cell division. A dendritic cell is a cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation. http://purl.obolibrary.org/obo/CL_0000435 alkali secreting cell http://purl.obolibrary.org/obo/CL_0000151 secretory cell http://purl.obolibrary.org/obo/GO_0044566 chondrocyte activation http://purl.obolibrary.org/obo/GO_0001775 cell activation A change in the morphology or behavior of a chondrocyte resulting from exposure to an activating factor such as a cellular or soluble ligand. A chondrocyte is a polymorphic cell that forms cartilage. http://purl.obolibrary.org/obo/CL_0000436 vaginal lubricant secreting cell http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell http://purl.obolibrary.org/obo/GO_0044872 lipoprotein localization http://purl.obolibrary.org/obo/GO_0033036 macromolecule localization Any process in which a lipoprotein is transported to, or maintained in, a specific location. http://purl.obolibrary.org/obo/CL_0000447 carbohydrate secreting cell http://purl.obolibrary.org/obo/CL_0000151 secretory cell http://purl.obolibrary.org/obo/GO_0044873 lipoprotein localization to membrane http://purl.obolibrary.org/obo/GO_0044872 lipoprotein localization A process in which a lipoprotein is transported to, or maintained in, a specific location in a membrane. http://purl.obolibrary.org/obo/CL_0000457 biogenic amine secreting cell http://purl.obolibrary.org/obo/CL_0000151 secretory cell http://purl.obolibrary.org/obo/GO_0044874 lipoprotein localization to outer membrane http://purl.obolibrary.org/obo/GO_0044873 lipoprotein localization to membrane A process in which a lipoprotein is transported to, or maintained in, a specific location in an outer membrane. http://purl.obolibrary.org/obo/CL_0000323 lysozyme secreting cell http://purl.obolibrary.org/obo/CL_0000154 protein secreting cell http://purl.obolibrary.org/obo/GO_0045019 negative regulation of nitric oxide biosynthetic process http://purl.obolibrary.org/obo/GO_0009890 negative regulation of biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nitric oxide. http://purl.obolibrary.org/obo/CL_0000470 digestive enzyme secreting cell http://purl.obolibrary.org/obo/CL_0000154 protein secreting cell http://purl.obolibrary.org/obo/GO_0045031 G protein-coupled ATP receptor activity http://purl.obolibrary.org/obo/GO_0045028 G protein-coupled purinergic nucleotide receptor activity Combining with ATP and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. http://purl.obolibrary.org/obo/CL_1000691 kidney interstitial myofibroblast http://purl.obolibrary.org/obo/CL_1000500 kidney interstitial cell http://purl.obolibrary.org/obo/GO_0045037 protein import into chloroplast stroma http://purl.obolibrary.org/obo/GO_0072598 protein localization to chloroplast The targeting and import of proteins into the chloroplast stroma. Import depends on ATP hydrolysis catalyzed by stromal chaperones. Chloroplast stromal proteins, such as the S subunit of rubisco, have a N-terminal stromal-import sequence of about 44 amino acids which is cleaved from the protein precursor after import. http://purl.obolibrary.org/obo/CL_0000551 unimodal nocireceptor http://purl.obolibrary.org/obo/CL_0000198 pain receptor cell http://purl.obolibrary.org/obo/GO_0045058 T cell selection http://purl.obolibrary.org/obo/GO_0002376 immune system process The process in which T cells that express T cell receptors that are restricted by self MHC protein complexes and tolerant to self antigens are selected for further maturation. http://purl.obolibrary.org/obo/CL_0000567 polymodal nocireceptor http://purl.obolibrary.org/obo/CL_0000198 pain receptor cell http://purl.obolibrary.org/obo/GO_0045095 keratin filament http://purl.obolibrary.org/obo/GO_0005882 intermediate filament A filament composed of acidic and basic keratins (types I and II), typically expressed in epithelial cells. The keratins are the most diverse classes of IF proteins, with a large number of keratin isoforms being expressed. Each type of epithelium always expresses a characteristic combination of type I and type II keratins. http://purl.obolibrary.org/obo/CL_0000544 slowly adapting mechanoreceptor cell http://purl.obolibrary.org/obo/CL_0000199 mechanoreceptor cell http://purl.obolibrary.org/obo/GO_0045103 intermediate filament-based process http://purl.obolibrary.org/obo/GO_0009987 cellular process Any cellular process that depends upon or alters the intermediate filament cytoskeleton, that part of the cytoskeleton comprising intermediate filaments and their associated proteins. http://purl.obolibrary.org/obo/CL_0000208 pH receptor cell http://purl.obolibrary.org/obo/CL_0000206 chemoreceptor cell http://purl.obolibrary.org/obo/GO_0045104 intermediate filament cytoskeleton organization http://purl.obolibrary.org/obo/GO_0045103 intermediate filament-based process A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising intermediate filaments and their associated proteins. http://purl.obolibrary.org/obo/GO_0045109 intermediate filament organization http://purl.obolibrary.org/obo/GO_0045104 intermediate filament cytoskeleton organization Control of the spatial distribution of intermediate filaments; includes organizing filaments into meshworks, bundles, or other structures, as by cross-linking. http://purl.obolibrary.org/obo/CL_0000489 scotopic photoreceptor cell http://purl.obolibrary.org/obo/CL_0000210 photoreceptor cell http://purl.obolibrary.org/obo/CL_0000732 amoeboid cell http://purl.obolibrary.org/obo/CL_0000219 motile cell http://purl.obolibrary.org/obo/GO_0045124 regulation of bone resorption http://purl.obolibrary.org/obo/GO_0046850 regulation of bone remodeling Any process that modulates the frequency, rate or extent of bone tissue loss (resorption). http://purl.obolibrary.org/obo/CL_0000238 non keratinizing barrier epithelial cell http://purl.obolibrary.org/obo/CL_0000240 stratified squamous epithelial cell http://purl.obolibrary.org/obo/GO_0045144 meiotic sister chromatid segregation http://purl.obolibrary.org/obo/GO_0000819 sister chromatid segregation The cell cycle process in which sister chromatids are organized and then physically separated and randomly apportioned to two sets during the second division of the meiotic cell cycle. http://purl.obolibrary.org/obo/CL_0000722 cystoblast http://purl.obolibrary.org/obo/CL_0000586 germ cell http://purl.obolibrary.org/obo/GO_0045190 isotype switching http://purl.obolibrary.org/obo/GO_0002312 B cell activation involved in immune response The switching of activated B cells from IgM biosynthesis to biosynthesis of other isotypes of immunoglobulin, accomplished through a recombination process involving an intrachromosomal deletion involving switch regions that reside 5' of each constant region gene segment in the immunoglobulin heavy chain locus. http://purl.obolibrary.org/obo/CL_0000309 copper accumulating cell http://purl.obolibrary.org/obo/CL_0000308 metal ion accumulating cell http://purl.obolibrary.org/obo/CL_0000310 iron accumulating cell http://purl.obolibrary.org/obo/CL_0000308 metal ion accumulating cell http://purl.obolibrary.org/obo/GO_0045191 regulation of isotype switching http://purl.obolibrary.org/obo/GO_0050864 regulation of B cell activation Any process that modulates the frequency, rate or extent of isotype switching. http://purl.obolibrary.org/obo/CL_0007019 epidermal mucus secreting cell http://purl.obolibrary.org/obo/CL_0000319 mucus secreting cell http://purl.obolibrary.org/obo/GO_0045196 establishment or maintenance of neuroblast polarity http://purl.obolibrary.org/obo/GO_0007163 establishment or maintenance of cell polarity Any cellular process that results in the specification, formation or maintenance of the apicobasal polarity of a neuroblast cell, a progenitor of the central nervous system. http://purl.obolibrary.org/obo/CL_0000256 uric acid accumulating cell http://purl.obolibrary.org/obo/CL_0000325 stuff accumulating cell http://purl.obolibrary.org/obo/CL_0000306 crystallin accumulating cell http://purl.obolibrary.org/obo/CL_0000325 stuff accumulating cell http://purl.obolibrary.org/obo/GO_0045200 establishment of neuroblast polarity http://purl.obolibrary.org/obo/GO_0045196 establishment or maintenance of neuroblast polarity The specification and formation of the apicobasal polarity of a neuroblast cell, a progenitor of the central nervous system. http://purl.obolibrary.org/obo/CL_0000308 metal ion accumulating cell http://purl.obolibrary.org/obo/CL_0000325 stuff accumulating cell http://purl.obolibrary.org/obo/CL_0000311 keratin accumulating cell http://purl.obolibrary.org/obo/CL_0000325 stuff accumulating cell http://purl.obolibrary.org/obo/GO_0045211 postsynaptic membrane http://purl.obolibrary.org/obo/GO_0097060 synaptic membrane A specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). Neurotransmitters cross the synaptic cleft and transmit the signal to the postsynaptic membrane. http://purl.obolibrary.org/obo/CL_0000326 glycogen accumulating cell http://purl.obolibrary.org/obo/CL_0000325 stuff accumulating cell http://purl.obolibrary.org/obo/GO_0045296 cadherin binding http://purl.obolibrary.org/obo/GO_0050839 cell adhesion molecule binding Binding to cadherin, a type I membrane protein involved in cell adhesion. http://purl.obolibrary.org/obo/CL_0000428 yolk cell http://purl.obolibrary.org/obo/CL_0000349 extraembryonic cell http://purl.obolibrary.org/obo/GO_0045314 regulation of compound eye photoreceptor development http://purl.obolibrary.org/obo/GO_0042478 regulation of eye photoreceptor cell development Any process that modulates the frequency, rate or extent of compound eye photoreceptor development. http://purl.obolibrary.org/obo/CL_1000083 stratified keratinized epithelial stem cell http://purl.obolibrary.org/obo/CL_0000357 stratified epithelial stem cell http://purl.obolibrary.org/obo/GO_0045315 positive regulation of compound eye photoreceptor development http://purl.obolibrary.org/obo/GO_0045314 regulation of compound eye photoreceptor development Any process that activates or increases the frequency, rate or extent of compound eye photoreceptor development. http://purl.obolibrary.org/obo/CL_1000085 stratified non keratinized epithelial stem cell http://purl.obolibrary.org/obo/CL_0000357 stratified epithelial stem cell http://purl.obolibrary.org/obo/GO_0045316 negative regulation of compound eye photoreceptor development http://purl.obolibrary.org/obo/GO_0045314 regulation of compound eye photoreceptor development Any process that stops, prevents, or reduces the frequency, rate or extent of compound eye photoreceptor development. http://purl.obolibrary.org/obo/CL_0000619 supporting cell (sensu Nematoda) http://purl.obolibrary.org/obo/CL_0000378 supporting cell (sensu Nematoda and Protostomia) http://purl.obolibrary.org/obo/CL_0000676 cap cell http://purl.obolibrary.org/obo/CL_0000378 supporting cell (sensu Nematoda and Protostomia) http://purl.obolibrary.org/obo/GO_0045428 regulation of nitric oxide biosynthetic process http://purl.obolibrary.org/obo/GO_0009889 regulation of biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nitric oxide. http://purl.obolibrary.org/obo/CL_0000416 polytene cell http://purl.obolibrary.org/obo/CL_0000412 polyploid cell http://purl.obolibrary.org/obo/CL_0000417 endopolyploid cell http://purl.obolibrary.org/obo/CL_0000412 polyploid cell http://purl.obolibrary.org/obo/GO_0045429 positive regulation of nitric oxide biosynthetic process http://purl.obolibrary.org/obo/GO_0009891 positive regulation of biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nitric oxide. http://purl.obolibrary.org/obo/CL_0000423 tip cell http://purl.obolibrary.org/obo/CL_0000422 mitogenic signaling cell http://purl.obolibrary.org/obo/GO_0045444 fat cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires specialized features of an adipocyte, an animal connective tissue cell specialized for the synthesis and storage of fat. http://purl.obolibrary.org/obo/CL_0000661 distal tip cell (sensu Nematoda) http://purl.obolibrary.org/obo/CL_0000422 mitogenic signaling cell http://purl.obolibrary.org/obo/GO_0045453 bone resorption http://purl.obolibrary.org/obo/GO_0001894 tissue homeostasis The process in which specialized cells known as osteoclasts degrade the organic and inorganic portions of bone, and endocytose and transport the degradation products. http://purl.obolibrary.org/obo/CL_0000662 neuroglioblast (sensu Nematoda) http://purl.obolibrary.org/obo/CL_0000468 neuroglioblast (sensu Nematoda and Protostomia) http://purl.obolibrary.org/obo/CL_0000490 photopic photoreceptor cell http://purl.obolibrary.org/obo/CL_0000488 visible light photoreceptor cell http://purl.obolibrary.org/obo/GO_0045463 R8 cell development http://purl.obolibrary.org/obo/GO_0042051 compound eye photoreceptor development The process whose specific outcome is the progression of the R8 photoreceptor over time, from its formation to the mature structure. The R8 photoreceptor is the founding receptor of each ommatidium. http://purl.obolibrary.org/obo/CL_0000687 R1 photoreceptor cell http://purl.obolibrary.org/obo/CL_2000019 compound eye photoreceptor cell http://purl.obolibrary.org/obo/GO_0045467 R7 cell development http://purl.obolibrary.org/obo/GO_0042051 compound eye photoreceptor development The process whose specific outcome is the progression of the R7 photoreceptor over time, from its formation to the mature structure. The R7 photoreceptor is the last photoreceptor to develop in the ommatidium. http://purl.obolibrary.org/obo/CL_0000690 R2 photoreceptor cell http://purl.obolibrary.org/obo/CL_2000019 compound eye photoreceptor cell http://purl.obolibrary.org/obo/CL_0000694 R3 photoreceptor cell http://purl.obolibrary.org/obo/CL_2000019 compound eye photoreceptor cell http://purl.obolibrary.org/obo/GO_0045476 nurse cell apoptotic process http://purl.obolibrary.org/obo/GO_0010623 programmed cell death involved in cell development Any apoptotic process in a nurse cell. During late oogenesis, following the transfer of substances from the nurse cells to the oocyte, nurse cell remnants are cleared from the egg chamber by apoptotic process. http://purl.obolibrary.org/obo/CL_0000697 R4 photoreceptor cell http://purl.obolibrary.org/obo/CL_2000019 compound eye photoreceptor cell http://purl.obolibrary.org/obo/CL_0000702 R5 photoreceptor cell http://purl.obolibrary.org/obo/CL_2000019 compound eye photoreceptor cell http://purl.obolibrary.org/obo/GO_0045477 regulation of nurse cell apoptotic process http://purl.obolibrary.org/obo/GO_2000241 regulation of reproductive process Any process that modulates the frequency, rate or extent of nurse cell apoptotic process. http://purl.obolibrary.org/obo/CL_0000705 R6 photoreceptor cell http://purl.obolibrary.org/obo/CL_2000019 compound eye photoreceptor cell http://purl.obolibrary.org/obo/GO_0045570 regulation of imaginal disc growth http://purl.obolibrary.org/obo/GO_0048638 regulation of developmental growth Any process that modulates the frequency, rate or extent of the growth of the imaginal disc. http://purl.obolibrary.org/obo/CL_0000709 R8 photoreceptor cell http://purl.obolibrary.org/obo/CL_2000019 compound eye photoreceptor cell http://purl.obolibrary.org/obo/GO_0045571 negative regulation of imaginal disc growth http://purl.obolibrary.org/obo/GO_0045570 regulation of imaginal disc growth Any process that stops, prevents, or reduces the frequency, rate or extent of imaginal disc growth. http://purl.obolibrary.org/obo/CL_0000707 R7 photoreceptor cell http://purl.obolibrary.org/obo/CL_2000019 compound eye photoreceptor cell http://purl.obolibrary.org/obo/GO_0045572 positive regulation of imaginal disc growth http://purl.obolibrary.org/obo/GO_0048639 positive regulation of developmental growth Any process that activates or increases the frequency, rate or extent of imaginal disc growth. http://purl.obolibrary.org/obo/CL_0000327 extracellular matrix secreting cell http://purl.obolibrary.org/obo/CL_0000499 stromal cell http://purl.obolibrary.org/obo/GO_0045583 regulation of cytotoxic T cell differentiation http://purl.obolibrary.org/obo/GO_0045580 regulation of T cell differentiation Any process that modulates the frequency, rate or extent of cytotoxic T cell differentiation. http://purl.obolibrary.org/obo/CL_0000334 vegetative cell (sensu Fungi) http://purl.obolibrary.org/obo/CL_0000521 fungal cell http://purl.obolibrary.org/obo/GO_0045584 negative regulation of cytotoxic T cell differentiation http://purl.obolibrary.org/obo/GO_0045583 regulation of cytotoxic T cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of cytotoxic T cell differentiation. http://purl.obolibrary.org/obo/CL_0000253 eurydendroid cell http://purl.obolibrary.org/obo/CL_0000527 efferent neuron http://purl.obolibrary.org/obo/CL_0000367 sheath cell (sensu Nematoda) http://purl.obolibrary.org/obo/CL_0000619 supporting cell (sensu Nematoda) http://purl.obolibrary.org/obo/GO_0045585 positive regulation of cytotoxic T cell differentiation http://purl.obolibrary.org/obo/GO_0045583 regulation of cytotoxic T cell differentiation Any process that activates or increases the frequency, rate or extent of cytotoxic T cell differentiation. http://purl.obolibrary.org/obo/CL_0000389 socket cell (sensu Nematoda) http://purl.obolibrary.org/obo/CL_0000658 cuticle secreting cell http://purl.obolibrary.org/obo/GO_0045586 regulation of gamma-delta T cell differentiation http://purl.obolibrary.org/obo/GO_0046643 regulation of gamma-delta T cell activation Any process that modulates the frequency, rate or extent of gamma-delta T cell differentiation. http://purl.obolibrary.org/obo/CL_0000378 supporting cell (sensu Nematoda and Protostomia) http://purl.obolibrary.org/obo/CL_0000630 supporting cell http://purl.obolibrary.org/obo/GO_0045587 negative regulation of gamma-delta T cell differentiation http://purl.obolibrary.org/obo/GO_0046644 negative regulation of gamma-delta T cell activation Any process that stops, prevents, or reduces the frequency, rate or extent of gamma-delta T cell differentiation. http://purl.obolibrary.org/obo/CL_0000384 ligament cell http://purl.obolibrary.org/obo/CL_0000630 supporting cell http://purl.obolibrary.org/obo/CL_0000529 pigmented epithelial cell http://purl.obolibrary.org/obo/CL_0000710 neurecto-epithelial cell http://purl.obolibrary.org/obo/GO_0045588 positive regulation of gamma-delta T cell differentiation http://purl.obolibrary.org/obo/GO_0046645 positive regulation of gamma-delta T cell activation Any process that activates or increases the frequency, rate or extent of gamma-delta T cell differentiation. http://purl.obolibrary.org/obo/CL_0000713 corona radiata cell http://purl.obolibrary.org/obo/CL_0000711 cumulus granulosa cell http://purl.obolibrary.org/obo/GO_0045592 regulation of cumulus cell differentiation http://purl.obolibrary.org/obo/GO_2000387 regulation of antral ovarian follicle growth Any process that modulates the frequency, rate or extent of ovarian cumulus cell differentiation. http://purl.obolibrary.org/obo/CL_0000719 posterior cone cell (sensu Endopterygota) http://purl.obolibrary.org/obo/CL_0000718 compound eye cone cell http://purl.obolibrary.org/obo/GO_0045593 negative regulation of cumulus cell differentiation http://purl.obolibrary.org/obo/GO_2000242 negative regulation of reproductive process Any process that stops, prevents, or reduces the frequency, rate or extent of ovarian cumulus cell differentiation. http://purl.obolibrary.org/obo/CL_0000720 anterior cone cell (sensu Endopterygota) http://purl.obolibrary.org/obo/CL_0000718 compound eye cone cell http://purl.obolibrary.org/obo/GO_0045594 positive regulation of cumulus cell differentiation http://purl.obolibrary.org/obo/GO_2000243 positive regulation of reproductive process Any process that activates or increases the frequency, rate or extent of ovarian cumulus cell differentiation. http://purl.obolibrary.org/obo/CL_0000721 equatorial cone cell (sensu Endopterygota) http://purl.obolibrary.org/obo/CL_0000718 compound eye cone cell http://purl.obolibrary.org/obo/CL_0001019 CD115-positive monocyte OR common dendritic progenitor http://purl.obolibrary.org/obo/CL_0002031 hematopoietic lineage restricted progenitor cell http://purl.obolibrary.org/obo/GO_0045598 regulation of fat cell differentiation http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the frequency, rate or extent of adipocyte differentiation. http://purl.obolibrary.org/obo/CL_1000697 kidney interstitial suppressor macrophage http://purl.obolibrary.org/obo/CL_1000500 kidney interstitial cell http://purl.obolibrary.org/obo/GO_0045599 negative regulation of fat cell differentiation http://purl.obolibrary.org/obo/GO_0045598 regulation of fat cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of adipocyte differentiation. http://purl.obolibrary.org/obo/CL_1000696 kidney interstitial inflammatory macrophage http://purl.obolibrary.org/obo/CL_1000500 kidney interstitial cell http://purl.obolibrary.org/obo/CL_1000695 kidney interstitial alternatively activated macrophage http://purl.obolibrary.org/obo/CL_1000500 kidney interstitial cell http://purl.obolibrary.org/obo/GO_0045600 positive regulation of fat cell differentiation http://purl.obolibrary.org/obo/GO_0045597 positive regulation of cell differentiation Any process that activates or increases the frequency, rate or extent of adipocyte differentiation. http://purl.obolibrary.org/obo/CL_0000995 CD34-positive, CD38-positive common myeloid progenitor OR CD34-positive, CD38-positive common lymphoid progenitor http://purl.obolibrary.org/obo/CL_0011026 progenitor cell http://purl.obolibrary.org/obo/GO_0045601 regulation of endothelial cell differentiation http://purl.obolibrary.org/obo/GO_0030856 regulation of epithelial cell differentiation Any process that modulates the frequency, rate or extent of endothelial cell differentiation. http://purl.obolibrary.org/obo/CL_0001012 CD7-negative lymphoid progenitor OR granulocyte monocyte progenitor http://purl.obolibrary.org/obo/CL_0011026 progenitor cell http://purl.obolibrary.org/obo/GO_0045602 negative regulation of endothelial cell differentiation http://purl.obolibrary.org/obo/GO_0045601 regulation of endothelial cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of endothelial cell differentiation. http://purl.obolibrary.org/obo/CL_0001030 CD117-positive common myeloid progenitor OR CD217-positive common lymphoid progenitor http://purl.obolibrary.org/obo/CL_0011026 progenitor cell http://purl.obolibrary.org/obo/CL_0000095 neuron associated cell http://purl.obolibrary.org/obo/CL_0002319 neural cell http://purl.obolibrary.org/obo/GO_0045603 positive regulation of endothelial cell differentiation http://purl.obolibrary.org/obo/GO_0045601 regulation of endothelial cell differentiation Any process that activates or increases the frequency, rate or extent of endothelial cell differentiation. http://purl.obolibrary.org/obo/CL_1001064 kidney artery smooth muscle cell http://purl.obolibrary.org/obo/CL_0019018 blood vessel smooth muscle cell http://purl.obolibrary.org/obo/GO_0045604 regulation of epidermal cell differentiation http://purl.obolibrary.org/obo/GO_0045682 regulation of epidermis development Any process that modulates the frequency, rate or extent of epidermal cell differentiation. http://purl.obolibrary.org/obo/CL_1001066 kidney arteriole smooth muscle cell http://purl.obolibrary.org/obo/CL_0019018 blood vessel smooth muscle cell http://purl.obolibrary.org/obo/GO_0045605 negative regulation of epidermal cell differentiation http://purl.obolibrary.org/obo/GO_0045683 negative regulation of epidermis development Any process that stops, prevents, or reduces the frequency, rate or extent of epidermal cell differentiation. http://purl.obolibrary.org/obo/CL_1001068 kidney venous system smooth muscle cell http://purl.obolibrary.org/obo/CL_0019018 blood vessel smooth muscle cell http://purl.obolibrary.org/obo/GO_0045606 positive regulation of epidermal cell differentiation http://purl.obolibrary.org/obo/GO_0045684 positive regulation of epidermis development Any process that activates or increases the frequency, rate or extent of epidermal cell differentiation. http://purl.obolibrary.org/obo/UBERON_0035548 colic artery http://purl.obolibrary.org/obo/UBERON_0001637 artery http://purl.obolibrary.org/obo/GO_0045607 regulation of inner ear auditory receptor cell differentiation http://purl.obolibrary.org/obo/GO_2000980 regulation of inner ear receptor cell differentiation Any process that modulates the frequency, rate or extent of auditory hair cell differentiation. http://purl.obolibrary.org/obo/UBERON_0035398 branch of external carotid artery http://purl.obolibrary.org/obo/UBERON_0001637 artery http://purl.obolibrary.org/obo/GO_0045609 positive regulation of inner ear auditory receptor cell differentiation http://purl.obolibrary.org/obo/GO_2000982 positive regulation of inner ear receptor cell differentiation Any process that activates or increases the frequency, rate or extent of auditory hair cell differentiation. http://purl.obolibrary.org/obo/UBERON_0035131 auditory ossicle cartilage element http://purl.obolibrary.org/obo/UBERON_0011004 pharyngeal arch cartilage http://purl.obolibrary.org/obo/GO_0045610 regulation of hemocyte differentiation http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the frequency, rate or extent of hemocyte differentiation. http://purl.obolibrary.org/obo/GO_0045611 negative regulation of hemocyte differentiation http://purl.obolibrary.org/obo/GO_0045610 regulation of hemocyte differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of hemocyte differentiation. http://purl.obolibrary.org/obo/UBERON_0035132 auditory ossicle pre-cartilage element http://purl.obolibrary.org/obo/UBERON_0035130 auditory ossicle endochondral element http://purl.obolibrary.org/obo/NCBITaxon_4896 Schizosaccharomyces pombe http://purl.obolibrary.org/obo/NCBITaxon_4895 Schizosaccharomyces http://purl.obolibrary.org/obo/GO_0045612 positive regulation of hemocyte differentiation http://purl.obolibrary.org/obo/GO_0045597 positive regulation of cell differentiation Any process that activates or increases the frequency, rate or extent of hemocyte differentiation. http://purl.obolibrary.org/obo/NCBITaxon_9682 Felis http://purl.obolibrary.org/obo/NCBITaxon_338152 Felinae http://purl.obolibrary.org/obo/NCBITaxon_2 Bacteria http://purl.obolibrary.org/obo/NCBITaxon_131567 cellular organisms http://purl.obolibrary.org/obo/GO_0045613 regulation of plasmatocyte differentiation http://purl.obolibrary.org/obo/GO_0045610 regulation of hemocyte differentiation Any process that modulates the frequency, rate or extent of plasmatocyte differentiation. http://purl.obolibrary.org/obo/NCBITaxon_4751 Fungi http://purl.obolibrary.org/obo/NCBITaxon_33154 Opisthokonta http://purl.obolibrary.org/obo/GO_0045614 negative regulation of plasmatocyte differentiation http://purl.obolibrary.org/obo/GO_0045613 regulation of plasmatocyte differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of plasmatocyte differentiation. http://purl.obolibrary.org/obo/NCBITaxon_4890 Ascomycota http://purl.obolibrary.org/obo/NCBITaxon_451864 Dikarya http://purl.obolibrary.org/obo/GO_0045615 positive regulation of plasmatocyte differentiation http://purl.obolibrary.org/obo/GO_0045613 regulation of plasmatocyte differentiation Any process that activates or increases the frequency, rate or extent of plasmatocyte differentiation. http://purl.obolibrary.org/obo/NCBITaxon_2172821 Multicrustacea http://purl.obolibrary.org/obo/NCBITaxon_6657 Crustacea http://purl.obolibrary.org/obo/GO_0045616 regulation of keratinocyte differentiation http://purl.obolibrary.org/obo/GO_0045604 regulation of epidermal cell differentiation Any process that modulates the frequency, rate or extent of keratinocyte differentiation. http://purl.obolibrary.org/obo/NCBITaxon_6712 Astacidea http://purl.obolibrary.org/obo/NCBITaxon_6692 Pleocyemata http://purl.obolibrary.org/obo/NCBITaxon_10090 Mus musculus http://purl.obolibrary.org/obo/NCBITaxon_862507 Mus http://purl.obolibrary.org/obo/GO_0045617 negative regulation of keratinocyte differentiation http://purl.obolibrary.org/obo/GO_0045616 regulation of keratinocyte differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of keratinocyte differentiation. http://purl.obolibrary.org/obo/UBERON_0035651 glans http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure http://purl.obolibrary.org/obo/GO_0045618 positive regulation of keratinocyte differentiation http://purl.obolibrary.org/obo/GO_0045616 regulation of keratinocyte differentiation Any process that activates or increases the frequency, rate or extent of keratinocyte differentiation. http://purl.obolibrary.org/obo/UBERON_0035383 lateral wall of nasopharynx http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure http://purl.obolibrary.org/obo/GO_0045622 regulation of T-helper cell differentiation http://purl.obolibrary.org/obo/GO_0043370 regulation of CD4-positive, alpha-beta T cell differentiation Any process that modulates the frequency, rate or extent of T-helper cell differentiation. http://purl.obolibrary.org/obo/UBERON_0035401 posterior wall of nasopharynx http://purl.obolibrary.org/obo/UBERON_0000328 gut wall http://purl.obolibrary.org/obo/GO_0045623 negative regulation of T-helper cell differentiation http://purl.obolibrary.org/obo/GO_0045622 regulation of T-helper cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of T-helper cell differentiation. http://purl.obolibrary.org/obo/UBERON_0035322 right common iliac artery http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure http://purl.obolibrary.org/obo/GO_0045624 positive regulation of T-helper cell differentiation http://purl.obolibrary.org/obo/GO_0045622 regulation of T-helper cell differentiation Any process that activates or increases the frequency, rate or extent of T-helper cell differentiation. http://purl.obolibrary.org/obo/UBERON_0035529 left common iliac artery http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure http://purl.obolibrary.org/obo/GO_0045625 regulation of T-helper 1 cell differentiation http://purl.obolibrary.org/obo/GO_0045622 regulation of T-helper cell differentiation Any process that modulates the frequency, rate or extent of T-helper 1 cell differentiation. http://purl.obolibrary.org/obo/UBERON_0035771 mesenteric plexus http://purl.obolibrary.org/obo/UBERON_0001816 autonomic nerve plexus http://purl.obolibrary.org/obo/UBERON_0035772 aortic plexus http://purl.obolibrary.org/obo/UBERON_0001816 autonomic nerve plexus http://purl.obolibrary.org/obo/GO_0045626 negative regulation of T-helper 1 cell differentiation http://purl.obolibrary.org/obo/GO_0045625 regulation of T-helper 1 cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of T-helper 1 cell differentiation. http://purl.obolibrary.org/obo/UBERON_0035428 postcapillary venule http://purl.obolibrary.org/obo/UBERON_0001979 venule http://purl.obolibrary.org/obo/GO_0045627 positive regulation of T-helper 1 cell differentiation http://purl.obolibrary.org/obo/GO_0045625 regulation of T-helper 1 cell differentiation Any process that activates or increases the frequency, rate or extent of T-helper 1 cell differentiation. http://purl.obolibrary.org/obo/UBERON_0035004 preputial swelling http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure http://purl.obolibrary.org/obo/GO_0045628 regulation of T-helper 2 cell differentiation http://purl.obolibrary.org/obo/GO_0045622 regulation of T-helper cell differentiation Any process that modulates the frequency, rate or extent of T-helper 2 cell differentiation. http://purl.obolibrary.org/obo/UBERON_0036301 vasculature of spleen http://purl.obolibrary.org/obo/UBERON_0006876 vasculature of organ http://purl.obolibrary.org/obo/GO_0045629 negative regulation of T-helper 2 cell differentiation http://purl.obolibrary.org/obo/GO_0045628 regulation of T-helper 2 cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of T-helper 2 cell differentiation. https://purl.brain-bican.org/ontology/mbao/MBA_467 Hypothalamic medial zone http://purl.obolibrary.org/obo/UBERON_0002272 medial zone of hypothalamus http://purl.obolibrary.org/obo/UBERON_0035788 layer of CA3 field http://purl.obolibrary.org/obo/UBERON_0002305 layer of hippocampus http://purl.obolibrary.org/obo/GO_0045630 positive regulation of T-helper 2 cell differentiation http://purl.obolibrary.org/obo/GO_0045628 regulation of T-helper 2 cell differentiation Any process that activates or increases the frequency, rate or extent of T-helper 2 cell differentiation. http://purl.obolibrary.org/obo/UBERON_0036186 fibroelastic connective tissue http://purl.obolibrary.org/obo/UBERON_0011824 fibrous connective tissue http://purl.obolibrary.org/obo/GO_0045631 regulation of mechanoreceptor differentiation http://purl.obolibrary.org/obo/GO_0045664 regulation of neuron differentiation Any process that modulates the frequency, rate or extent of mechanoreceptor differentiation. https://purl.brain-bican.org/ontology/mbao/MBA_784 corticospinal tract https://purl.brain-bican.org/ontology/mbao/MBA_1009 fiber tracts http://purl.obolibrary.org/obo/GO_0045632 negative regulation of mechanoreceptor differentiation http://purl.obolibrary.org/obo/GO_0045665 negative regulation of neuron differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of mechanoreceptor differentiation. http://purl.obolibrary.org/obo/UBERON_0035020 left vagus X nerve trunk http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure http://purl.obolibrary.org/obo/UBERON_0035021 right vagus X nerve trunk http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure http://purl.obolibrary.org/obo/GO_0045633 positive regulation of mechanoreceptor differentiation http://purl.obolibrary.org/obo/GO_0045666 positive regulation of neuron differentiation Any process that activates or increases the frequency, rate or extent of mechanoreceptor differentiation. http://purl.obolibrary.org/obo/GO_0045634 regulation of melanocyte differentiation http://purl.obolibrary.org/obo/GO_0050932 regulation of pigment cell differentiation Any process that modulates the frequency, rate or extent of melanocyte differentiation. http://purl.obolibrary.org/obo/UBERON_0035096 fascia of tail http://purl.obolibrary.org/obo/UBERON_0008982 fascia http://purl.obolibrary.org/obo/UBERON_0035769 mesenteric ganglion http://purl.obolibrary.org/obo/UBERON_0003964 prevertebral ganglion http://purl.obolibrary.org/obo/UBERON_0034994 hindbrain cortical intermediate zone http://purl.obolibrary.org/obo/UBERON_0004040 cortical intermediate zone http://purl.obolibrary.org/obo/GO_0045635 negative regulation of melanocyte differentiation http://purl.obolibrary.org/obo/GO_0050941 negative regulation of pigment cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of melanocyte differentiation. https://purl.brain-bican.org/ontology/mbao/MBA_73 ventricular systems http://purl.obolibrary.org/obo/UBERON_0005281 ventricular system of central nervous system http://purl.obolibrary.org/obo/GO_0045636 positive regulation of melanocyte differentiation http://purl.obolibrary.org/obo/GO_0050942 positive regulation of pigment cell differentiation Any process that activates or increases the frequency, rate or extent of melanocyte differentiation. http://purl.obolibrary.org/obo/UBERON_0036290 myocardium of anterior wall of left ventricle http://purl.obolibrary.org/obo/UBERON_0006566 left ventricle myocardium http://purl.obolibrary.org/obo/GO_0045640 regulation of basophil differentiation http://purl.obolibrary.org/obo/GO_0030852 regulation of granulocyte differentiation Any process that modulates the frequency, rate or extent of basophil differentiation. http://purl.obolibrary.org/obo/GO_0045641 negative regulation of basophil differentiation http://purl.obolibrary.org/obo/GO_0045640 regulation of basophil differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of basophil differentiation. http://purl.obolibrary.org/obo/UBERON_0036291 myocardium of anterior wall of right ventricle http://purl.obolibrary.org/obo/UBERON_0006567 right ventricle myocardium http://purl.obolibrary.org/obo/GO_0045642 positive regulation of basophil differentiation http://purl.obolibrary.org/obo/GO_0045640 regulation of basophil differentiation Any process that activates or increases the frequency, rate or extent of basophil differentiation. http://purl.obolibrary.org/obo/GO_0045643 regulation of eosinophil differentiation http://purl.obolibrary.org/obo/GO_0030852 regulation of granulocyte differentiation Any process that modulates the frequency, rate or extent of eosinophil differentiation. http://purl.obolibrary.org/obo/GO_0045644 negative regulation of eosinophil differentiation http://purl.obolibrary.org/obo/GO_0045643 regulation of eosinophil differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of eosinophil differentiation. http://purl.obolibrary.org/obo/GO_0045645 positive regulation of eosinophil differentiation http://purl.obolibrary.org/obo/GO_0045643 regulation of eosinophil differentiation Any process that activates or increases the frequency, rate or extent of eosinophil differentiation. http://purl.obolibrary.org/obo/GO_0045647 negative regulation of erythrocyte differentiation http://purl.obolibrary.org/obo/GO_0045646 regulation of erythrocyte differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of erythrocyte differentiation. http://purl.obolibrary.org/obo/GO_0045648 positive regulation of erythrocyte differentiation http://purl.obolibrary.org/obo/GO_0045646 regulation of erythrocyte differentiation Any process that activates or increases the frequency, rate or extent of erythrocyte differentiation. http://purl.obolibrary.org/obo/GO_0045652 regulation of megakaryocyte differentiation http://purl.obolibrary.org/obo/GO_0045637 regulation of myeloid cell differentiation Any process that modulates the frequency, rate or extent of megakaryocyte differentiation. http://purl.obolibrary.org/obo/GO_0045653 negative regulation of megakaryocyte differentiation http://purl.obolibrary.org/obo/GO_0045652 regulation of megakaryocyte differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of megakaryocyte differentiation. http://purl.obolibrary.org/obo/GO_0045654 positive regulation of megakaryocyte differentiation http://purl.obolibrary.org/obo/GO_0045652 regulation of megakaryocyte differentiation Any process that activates or increases the frequency, rate or extent of megakaryocyte differentiation. http://purl.obolibrary.org/obo/GO_0045655 regulation of monocyte differentiation http://purl.obolibrary.org/obo/GO_0002761 regulation of myeloid leukocyte differentiation Any process that modulates the frequency, rate or extent of monocyte differentiation. http://purl.obolibrary.org/obo/GO_0045656 negative regulation of monocyte differentiation http://purl.obolibrary.org/obo/GO_0045655 regulation of monocyte differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of monocyte differentiation. http://purl.obolibrary.org/obo/GO_0045657 positive regulation of monocyte differentiation http://purl.obolibrary.org/obo/GO_0045655 regulation of monocyte differentiation Any process that activates or increases the frequency, rate or extent of monocyte differentiation. http://purl.obolibrary.org/obo/GO_0045658 regulation of neutrophil differentiation http://purl.obolibrary.org/obo/GO_0030852 regulation of granulocyte differentiation Any process that modulates the frequency, rate or extent of neutrophil differentiation. https://purl.brain-bican.org/ontology/mbao/MBA_904 Medial septal complex http://purl.obolibrary.org/obo/UBERON_0007629 medial septal complex http://purl.obolibrary.org/obo/GO_0045659 negative regulation of neutrophil differentiation http://purl.obolibrary.org/obo/GO_0045658 regulation of neutrophil differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of neutrophil differentiation. http://purl.obolibrary.org/obo/GO_0045660 positive regulation of neutrophil differentiation http://purl.obolibrary.org/obo/GO_0045658 regulation of neutrophil differentiation Any process that activates or increases the frequency, rate or extent of neutrophil differentiation. http://purl.obolibrary.org/obo/GO_0045661 regulation of myoblast differentiation http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. http://purl.obolibrary.org/obo/GO_0045662 negative regulation of myoblast differentiation http://purl.obolibrary.org/obo/GO_0045661 regulation of myoblast differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. http://purl.obolibrary.org/obo/GO_0045663 positive regulation of myoblast differentiation http://purl.obolibrary.org/obo/GO_0045597 positive regulation of cell differentiation Any process that activates or increases the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. http://purl.obolibrary.org/obo/GO_0045667 regulation of osteoblast differentiation http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the frequency, rate or extent of osteoblast differentiation. http://purl.obolibrary.org/obo/UBERON_0035130 auditory ossicle endochondral element http://purl.obolibrary.org/obo/UBERON_0010363 endochondral element http://purl.obolibrary.org/obo/GO_0045668 negative regulation of osteoblast differentiation http://purl.obolibrary.org/obo/GO_0045667 regulation of osteoblast differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of osteoblast differentiation. http://purl.obolibrary.org/obo/UBERON_0035927 sulcus of parietal lobe http://purl.obolibrary.org/obo/UBERON_0013118 sulcus of brain https://purl.brain-bican.org/ontology/mbao/MBA_1024 grooves http://purl.obolibrary.org/obo/UBERON_0013118 sulcus of brain http://purl.obolibrary.org/obo/GO_0045669 positive regulation of osteoblast differentiation http://purl.obolibrary.org/obo/GO_0045597 positive regulation of cell differentiation Any process that activates or increases the frequency, rate or extent of osteoblast differentiation. http://purl.obolibrary.org/obo/GO_0045670 regulation of osteoclast differentiation http://purl.obolibrary.org/obo/GO_0002761 regulation of myeloid leukocyte differentiation Any process that modulates the frequency, rate or extent of osteoclast differentiation. http://purl.obolibrary.org/obo/CLM_5006977 S1pr1,Crym,Grin2c (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5001605 Apod,Npy (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/GO_0045671 negative regulation of osteoclast differentiation http://purl.obolibrary.org/obo/GO_0045670 regulation of osteoclast differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of osteoclast differentiation. http://purl.obolibrary.org/obo/CLM_5022219 Col25a1,C230072F16Rik (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/GO_0045672 positive regulation of osteoclast differentiation http://purl.obolibrary.org/obo/GO_0045670 regulation of osteoclast differentiation Any process that activates or increases the frequency, rate or extent of osteoclast differentiation. http://purl.obolibrary.org/obo/CLM_5022254 Plin3,Grm7 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/GO_0045676 regulation of R7 cell differentiation http://purl.obolibrary.org/obo/GO_0110116 regulation of compound eye photoreceptor cell differentiation Any process that modulates the frequency, rate or extent of R7 differentiation. http://purl.obolibrary.org/obo/CLM_5022244 C1ql1,Gstp1 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/GO_0045677 negative regulation of R7 cell differentiation http://purl.obolibrary.org/obo/GO_0045676 regulation of R7 cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of R7cell differentiation. http://purl.obolibrary.org/obo/CLM_5001604 Cldn11,Anln (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5000354 Gabra6,Ror1 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/GO_0045678 positive regulation of R7 cell differentiation http://purl.obolibrary.org/obo/GO_0045676 regulation of R7 cell differentiation Any process that activates or increases the frequency, rate or extent of R7 cell differentiation. http://purl.obolibrary.org/obo/CLM_5022213 Cnmd (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/GO_0045679 regulation of R8 cell differentiation http://purl.obolibrary.org/obo/GO_0110116 regulation of compound eye photoreceptor cell differentiation Any process that modulates the frequency, rate or extent of R8 differentiation. http://purl.obolibrary.org/obo/CLM_5006967 Aqp4,A330076C08Rik,Fbln5,Mdga2 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/GO_0045680 negative regulation of R8 cell differentiation http://purl.obolibrary.org/obo/GO_0045679 regulation of R8 cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of R8 cell differentiation. http://purl.obolibrary.org/obo/CLM_5007041 Apod,Mybpc1,Syk (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/GO_0045681 positive regulation of R8 cell differentiation http://purl.obolibrary.org/obo/GO_0045679 regulation of R8 cell differentiation Any process that activates or increases the frequency, rate or extent of R8 cell differentiation. http://purl.obolibrary.org/obo/CLM_5000363 Tmem212,Rarres2 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5016796 Sln (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5016826 Slc47a1 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5000367 Cldn11,Gjc3 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5007652 Gm34838 (NSforest). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/GO_0045682 regulation of epidermis development http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of epidermis development. http://purl.obolibrary.org/obo/CLM_5001586 Aqp4,Prss23,Igfbp2 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/GO_0045683 negative regulation of epidermis development http://purl.obolibrary.org/obo/GO_0045682 regulation of epidermis development Any process that stops, prevents, or reduces the frequency, rate or extent of epidermis development. http://purl.obolibrary.org/obo/CLM_5016807 C4b,Atp13a4 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/GO_0045684 positive regulation of epidermis development http://purl.obolibrary.org/obo/GO_0045682 regulation of epidermis development Any process that activates or increases the frequency, rate or extent of epidermis development. http://purl.obolibrary.org/obo/CLM_5022189 Rasl10b,Igfbp5 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/GO_0045700 regulation of spermatid nuclear differentiation http://purl.obolibrary.org/obo/GO_1903353 regulation of nucleus organization Any process that modulates the frequency, rate or extent of spermatid nuclear differentiation. http://purl.obolibrary.org/obo/CLM_5007000 Fndc3c1,Ecrg4 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/GO_0045701 negative regulation of spermatid nuclear differentiation http://purl.obolibrary.org/obo/GO_2000242 negative regulation of reproductive process Any process that stops, prevents, or reduces the frequency, rate or extent of spermatid nuclear differentiation. http://purl.obolibrary.org/obo/CLM_5007988 Frzb, Apod (NSforest). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/GO_0045702 positive regulation of spermatid nuclear differentiation http://purl.obolibrary.org/obo/GO_2000243 positive regulation of reproductive process Any process that activates or increases the frequency, rate or extent of spermatid nuclear differentiation. http://purl.obolibrary.org/obo/CLM_5001587 Gja1,Hs3st3a1,Slco1c1 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/GO_0045719 negative regulation of glycogen biosynthetic process http://purl.obolibrary.org/obo/GO_0070874 negative regulation of glycogen metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen. http://purl.obolibrary.org/obo/CLM_5007031 9630013A20Rik,Piezo2,Ptprb (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/GO_0045721 negative regulation of gluconeogenesis http://purl.obolibrary.org/obo/GO_0045912 negative regulation of carbohydrate metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of gluconeogenesis. http://purl.obolibrary.org/obo/CLM_5001570 Gabra6,Pvalb (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/GO_0045722 positive regulation of gluconeogenesis http://purl.obolibrary.org/obo/GO_0010907 positive regulation of glucose metabolic process Any process that activates or increases the frequency, rate or extent of gluconeogenesis. http://purl.obolibrary.org/obo/CLM_5001561 Il22,Rftn1 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/GO_0045723 positive regulation of fatty acid biosynthetic process http://purl.obolibrary.org/obo/GO_0046889 positive regulation of lipid biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids. http://purl.obolibrary.org/obo/CLM_1000001 NS forest marker set of alveolar adventitial fibroblast (Human lung). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/GO_0045724 positive regulation of cilium assembly http://purl.obolibrary.org/obo/GO_0120034 positive regulation of plasma membrane bounded cell projection assembly Any process that activates or increases the frequency, rate or extent of the formation of a cilium. http://purl.obolibrary.org/obo/CLM_1000002 NS forest marker set of alveolar type 1 fibroblast cell (Human lung). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/GO_0045725 positive regulation of glycogen biosynthetic process http://purl.obolibrary.org/obo/GO_0070875 positive regulation of glycogen metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen. http://purl.obolibrary.org/obo/CLM_1000003 NS forest marker set of alveolar macrophage (Human lung). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/GO_0045729 respiratory burst at fertilization http://purl.obolibrary.org/obo/GO_0045730 respiratory burst The phase of elevated metabolic activity, during which oxygen consumption increases, that occurs at fertilization. An enhanced uptake of oxygen leads to the production of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals. Capacitation, a necessary prerequisite event to successful fertilization, can be induced by reactive oxygen species in vitro; hydrogen peroxide is used as an extracellular oxidant to cross-link the protective surface envelopes. http://purl.obolibrary.org/obo/CLM_1000004 NS forest marker set of CCL3-positive alveolar macrophage (Human lung). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/GO_0045732 positive regulation of protein catabolic process http://purl.obolibrary.org/obo/GO_0009896 positive regulation of catabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds. http://purl.obolibrary.org/obo/CLM_1000005 NS forest marker set of metallothionein-positive alveolar macrophage (Human lung). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/GO_0045745 positive regulation of G protein-coupled receptor signaling pathway http://purl.obolibrary.org/obo/GO_0008277 regulation of G protein-coupled receptor signaling pathway Any process that activates or increases the frequency, rate or extent of G protein-coupled receptor signaling pathway activity. http://purl.obolibrary.org/obo/CLM_1000006 NS forest marker set of cycling alveolar macrophage (Human lung). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/GO_0045759 negative regulation of action potential http://purl.obolibrary.org/obo/GO_0098900 regulation of action potential Any process that stops, prevents, or reduces the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels. http://purl.obolibrary.org/obo/CLM_1000008 NS forest marker set of pulmonary alveolar type 1 cell (Human lung). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/GO_0045760 positive regulation of action potential http://purl.obolibrary.org/obo/GO_0098900 regulation of action potential Any process that activates or increases the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels. http://purl.obolibrary.org/obo/CLM_1000009 NS forest marker set of pulmonary alveolar type 2 cell (Human lung). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/GO_0045766 positive regulation of angiogenesis http://purl.obolibrary.org/obo/GO_0045765 regulation of angiogenesis Any process that activates or increases angiogenesis. http://purl.obolibrary.org/obo/CLM_1000010 NS forest marker set of cycling pulmonary alveolar type 2 cell (Human lung). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/GO_0045769 negative regulation of asymmetric cell division http://purl.obolibrary.org/obo/GO_0009786 regulation of asymmetric cell division Any process that stops, prevents, or reduces the frequency, rate or extent of asymmetric cell division. http://purl.obolibrary.org/obo/CLM_1000026 NS forest marker set of bronchial goblet cell (Human lung). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/GO_0045770 positive regulation of asymmetric cell division http://purl.obolibrary.org/obo/GO_0009786 regulation of asymmetric cell division Any process that activates or increases the frequency, rate or extent of asymmetric cell division. http://purl.obolibrary.org/obo/CLM_1000027 NS forest marker set of nasal mucosa goblet cell (Human lung). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/GO_0045779 negative regulation of bone resorption http://purl.obolibrary.org/obo/GO_0046851 negative regulation of bone remodeling Any process that stops, prevents, or reduces the frequency, rate or extent of bone resorption. http://purl.obolibrary.org/obo/CLM_1000031 NS forest marker set of lung interstitial macrophage (Human lung). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/GO_0045780 positive regulation of bone resorption http://purl.obolibrary.org/obo/GO_0045124 regulation of bone resorption Any process that activates or increases the frequency, rate or extent of bone resorption. http://purl.obolibrary.org/obo/CLM_1000032 NS forest marker set of pulmonary ionocyte (Human lung). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/GO_0045787 positive regulation of cell cycle http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the rate or extent of progression through the cell cycle. http://purl.obolibrary.org/obo/CLM_1000041 NS forest marker set of multiciliated columnar cell of tracheobronchial tree (Human lung). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_1000043 NS forest marker set of pulmonary neuroendocrine cell (Human lung). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/GO_0045881 positive regulation of sporulation resulting in formation of a cellular spore http://purl.obolibrary.org/obo/GO_0043938 positive regulation of sporulation Any process that activates or increases the frequency, rate or extent of sporulation. http://purl.obolibrary.org/obo/CLM_1000046 NS forest marker set of pulmonary interstitial fibroblast (Human lung). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/GO_0045922 negative regulation of fatty acid metabolic process http://purl.obolibrary.org/obo/GO_0045833 negative regulation of lipid metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving fatty acids. http://purl.obolibrary.org/obo/CLM_1000047 NS forest marker set of lung pericyte (Human lung). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/GO_0045923 positive regulation of fatty acid metabolic process http://purl.obolibrary.org/obo/GO_0045834 positive regulation of lipid metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving fatty acids. http://purl.obolibrary.org/obo/CLM_1000052 NS forest marker set of airway submucosal gland collecting duct epithelial cell (Human lung). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/GO_0045937 positive regulation of phosphate metabolic process http://purl.obolibrary.org/obo/GO_0010562 positive regulation of phosphorus metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving phosphates. http://purl.obolibrary.org/obo/CLM_1000053 NS forest marker set of mucus secreting cell of bronchus submucosal gland (Human lung). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/GO_0046013 regulation of T cell homeostatic proliferation http://purl.obolibrary.org/obo/GO_0042129 regulation of T cell proliferation Any process that modulates the frequency, rate or extent of resting T cell proliferation. http://purl.obolibrary.org/obo/CLM_1000054 NS forest marker set of serous secreting cell of bronchus submucosal gland (Human lung). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/GO_0046532 regulation of photoreceptor cell differentiation http://purl.obolibrary.org/obo/GO_0045664 regulation of neuron differentiation Any process that modulates the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster. http://purl.obolibrary.org/obo/CLM_1000056 NS forest marker set of tracheobronchial smooth muscle cell (Human lung). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/GO_0046533 negative regulation of photoreceptor cell differentiation http://purl.obolibrary.org/obo/GO_0045665 negative regulation of neuron differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster. http://purl.obolibrary.org/obo/CLM_1000059 NS forest marker set of respiratory tract suprabasal cell (Human lung). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/GO_0046534 positive regulation of photoreceptor cell differentiation http://purl.obolibrary.org/obo/GO_0045666 positive regulation of neuron differentiation Any process that activates or increases the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster. http://purl.obolibrary.org/obo/CLM_1000061 NS forest marker set of brush cell of tracheobronchial tree (Human lung). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/GO_0046621 negative regulation of organ growth http://purl.obolibrary.org/obo/GO_0048640 negative regulation of developmental growth Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organ of an organism. http://purl.obolibrary.org/obo/GO_0046622 positive regulation of organ growth http://purl.obolibrary.org/obo/GO_0048639 positive regulation of developmental growth Any process that activates or increases the frequency, rate or extent of growth of an organ of an organism. http://purl.obolibrary.org/obo/GO_0046625 sphingolipid binding http://purl.obolibrary.org/obo/GO_0008289 lipid binding Binding to a sphingolipid, a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid). http://purl.obolibrary.org/obo/CLM_1000063 NS forest marker set of pvalb chandelier GABAergic interneuron (Human neocortex). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/GO_0046637 regulation of alpha-beta T cell differentiation http://purl.obolibrary.org/obo/GO_0045580 regulation of T cell differentiation Any process that modulates the frequency, rate or extent of alpha-beta T cell differentiation. http://purl.obolibrary.org/obo/CLM_1000065 NS forest marker set of L2/3 intratelencephalic projecting glutamatergic neuron (Human neocortex). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/GO_0046638 positive regulation of alpha-beta T cell differentiation http://purl.obolibrary.org/obo/GO_0046637 regulation of alpha-beta T cell differentiation Any process that activates or increases the frequency, rate or extent of alpha-beta T cell differentiation. http://purl.obolibrary.org/obo/CLM_1000066 NS forest marker set of L4 intratelencephalic projecting glutamatergic neuron (Human neocortex). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/GO_0046639 negative regulation of alpha-beta T cell differentiation http://purl.obolibrary.org/obo/GO_0046637 regulation of alpha-beta T cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of alpha-beta T cell differentiation. http://purl.obolibrary.org/obo/CLM_1000067 NS forest marker set of L5 extratelencephalic projecting glutamatergic cortical neuron (Human neocortex). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/GO_0046643 regulation of gamma-delta T cell activation http://purl.obolibrary.org/obo/GO_0050863 regulation of T cell activation Any process that modulates the frequency, rate or extent of gamma-delta T cell activation. http://purl.obolibrary.org/obo/CLM_1000068 NS forest marker set of L5 intratelencephalic projecting glutamatergic neuron (Human neocortex). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/GO_0046644 negative regulation of gamma-delta T cell activation http://purl.obolibrary.org/obo/GO_0050868 negative regulation of T cell activation Any process that stops, prevents, or reduces the frequency, rate or extent of gamma-delta T cell activation. http://purl.obolibrary.org/obo/CLM_1000069 NS forest marker set of L5/6 near-projecting glutamatergic neuron (Human neocortex). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_1000070 NS forest marker set of L6 corticothalamic-projecting glutamatergic cortical neuron (Human neocortex). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/GO_0046645 positive regulation of gamma-delta T cell activation http://purl.obolibrary.org/obo/GO_0046643 regulation of gamma-delta T cell activation Any process that activates or increases the frequency, rate or extent of gamma-delta T cell activation. http://purl.obolibrary.org/obo/CLM_1000071 NS forest marker set of L6 intratelencephalic projecting glutamatergic neuron (Human neocortex). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_1000072 NS forest marker set of L6 intratelencephalic projecting Car3 glutamatergic neuron (Human neocortex). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/GO_0046822 regulation of nucleocytoplasmic transport http://purl.obolibrary.org/obo/GO_0032386 regulation of intracellular transport Any process that modulates the frequency, rate or extent of the directed movement of substances between the nucleus and the cytoplasm. http://purl.obolibrary.org/obo/CLM_1000073 NS forest marker set of L6b glutamatergic neuron of the primary motor cortex (Human neocortex). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_1000074 NS forest marker set of lamp5 GABAergic interneuron (Human neocortex). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/GO_0046823 negative regulation of nucleocytoplasmic transport http://purl.obolibrary.org/obo/GO_0046822 regulation of nucleocytoplasmic transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances between the cytoplasm and the nucleus. http://purl.obolibrary.org/obo/CLM_1000075 NS forest marker set of Lamp5 Lhx6 neuron (Human neocortex). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_1000079 NS forest marker set of PAX6 GABAergic interneuron (Human neocortex). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/GO_0046824 positive regulation of nucleocytoplasmic transport http://purl.obolibrary.org/obo/GO_0046822 regulation of nucleocytoplasmic transport Any process that activates or increases the frequency, rate or extent of the directed movement of substances between the nucleus and the cytoplasm. http://purl.obolibrary.org/obo/CLM_1000080 NS forest marker set of pvalb GABAergic interneuron (Human neocortex). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_1000081 NS forest marker set of sncg GABAergic interneuron (Human neocortex). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_1000082 NS forest marker set of sst GABAergic interneuron (Human neocortex). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/GO_0046827 positive regulation of protein export from nucleus http://purl.obolibrary.org/obo/GO_0046825 regulation of protein export from nucleus Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the nucleus into the cytoplasm. http://purl.obolibrary.org/obo/CLM_1000083 NS forest marker set of sst chodl GABAergic interneuron (Human neocortex). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_1000085 NS forest marker set of VIP GABAergic interneuron (Human neocortex). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/GO_0046849 bone remodeling http://purl.obolibrary.org/obo/GO_0048771 tissue remodeling The continuous turnover of bone matrix and mineral that involves first, an increase in resorption (osteoclastic activity) and later, reactive bone formation (osteoblastic activity). The process of bone remodeling takes place in the adult skeleton at discrete foci. The process ensures the mechanical integrity of the skeleton throughout life and plays an important role in calcium homeostasis. An imbalance in the regulation of bone resorption and bone formation results in many of the metabolic bone diseases, such as osteoporosis. http://purl.obolibrary.org/obo/CLM_5007021 Pdgfra,Cenpf,Cenpa (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022142 Ppp1r17 4 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/GO_0046850 regulation of bone remodeling http://purl.obolibrary.org/obo/GO_0034103 regulation of tissue remodeling Any process that modulates the frequency, rate or extent of bone remodeling, the processes of bone formation and resorption that combine to maintain skeletal integrity. http://purl.obolibrary.org/obo/CLM_5001572 Pcp2,Stk17b (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5016784 Afap1l2,Coro6 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/GO_0046851 negative regulation of bone remodeling http://purl.obolibrary.org/obo/GO_0046850 regulation of bone remodeling Any process that stops, prevents, or reduces the frequency, rate or extent of bone remodeling. http://purl.obolibrary.org/obo/CLM_5022282 C1qa,Tmem119 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5001575 Gabra6,Gap43,Rab37 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/GO_0046852 positive regulation of bone remodeling http://purl.obolibrary.org/obo/GO_0046850 regulation of bone remodeling Any process that activates or increases the frequency, rate or extent of bone remodeling. http://purl.obolibrary.org/obo/CLM_5007975 Sln, Fat2 (NSforest). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5007042 Apod,Mybpc1,Rasgef1c (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/GO_0046865 terpenoid transport http://purl.obolibrary.org/obo/GO_0046864 isoprenoid transport The directed movement of terpenoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Terpenoids are a class of compounds characterized by an isoprenoid chemical structure and include derivatives with various functional groups. http://purl.obolibrary.org/obo/CLM_5007990 Slc6a13, Foxc1 (NSforest). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5006976 S1pr1,Ranbp3l,Emx2os,Zic4 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/GO_0048103 somatic stem cell division http://purl.obolibrary.org/obo/GO_0017145 stem cell division The self-renewing division of a somatic stem cell, a stem cell that can give rise to cell types of the body other than those of the germ-line. http://purl.obolibrary.org/obo/CLM_5006965 Gja1,A330076C08Rik,Otx2,Unc13c (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5016790 Gabra6 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/GO_0048194 Golgi vesicle budding http://purl.obolibrary.org/obo/GO_0006900 vesicle budding from membrane The evagination of the Golgi membrane, resulting in formation of a vesicle. http://purl.obolibrary.org/obo/CLM_5024423 Ctps, Cldn11 (CAS evidence). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5006942 Cdh1,Acvr1c,Adamts15,Pax2 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/GO_0048199 vesicle targeting, to, from or within Golgi http://purl.obolibrary.org/obo/GO_0006903 vesicle targeting The process in which vesicles are directed to specific destination membranes during transport to, from or within the Golgi apparatus; mediated by the addition of specific coat proteins, including COPI and COPII proteins and clathrin, to the membrane during vesicle formation. http://purl.obolibrary.org/obo/CLM_5007044 Slc47a1,Dapl1 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022179 Slc36a2,Sfrp5 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/GO_0048289 isotype switching to IgE isotypes http://purl.obolibrary.org/obo/GO_0045190 isotype switching The switching of activated B cells from IgM biosynthesis to IgE biosynthesis, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and IgE constant region gene segments in the immunoglobulin heavy chain locus. http://purl.obolibrary.org/obo/CLM_5007035 Cldn11,A230001M10Rik,Spock3,Rhoj (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022248 9630013A20Rik,Grin2b (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/GO_0048542 lymph gland development http://purl.obolibrary.org/obo/GO_0048534 hematopoietic or lymphoid organ development The process whose specific outcome is the progression of the lymph gland over time, from its formation to the mature structure. The lymph gland is one of the sites of hemocyte differentiation. It consists of three to six bilaterally paired lobes that are attached to the cardioblasts during larval stages, and it degenerates during pupal stages. http://purl.obolibrary.org/obo/CLM_5006968 Myoc,Lhx2,Kcne1l,Alpk1 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5001568 Zfp385c,Tfap2b (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/GO_0048639 positive regulation of developmental growth http://purl.obolibrary.org/obo/GO_0048638 regulation of developmental growth Any process that activates, maintains or increases the rate of developmental growth. http://purl.obolibrary.org/obo/CLM_5006981 Gja1,Chrdl1,Ano1,Il33 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5016822 Egflam,Man1a (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/GO_0048770 pigment granule http://purl.obolibrary.org/obo/GO_0031410 cytoplasmic vesicle A small, subcellular membrane-bounded vesicle containing pigment and/or pigment precursor molecules. Pigment granule biogenesis is poorly understood, as pigment granules are derived from multiple sources including the endoplasmic reticulum, coated vesicles, lysosomes, and endosomes. http://purl.obolibrary.org/obo/CLM_5007024 Gpr17,Bgn,Gstp1,C1ql1 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5016795 Gap43 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5006975 S1pr1,Fam163a,Kcnq3,Kcnq1ot1 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/GO_0048793 pronephros development http://purl.obolibrary.org/obo/GO_0001822 kidney development The process whose specific outcome is the progression of the pronephros over time, from its formation to the mature structure. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life. http://purl.obolibrary.org/obo/CLM_5022218 Otx2,Nkx2-4 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5001563 Fat2,Slc6a5,Cgnl1 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5006980 S1pr1,Adamts18,Crym (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/GO_0048799 animal organ maturation http://purl.obolibrary.org/obo/GO_0071695 anatomical structure maturation A developmental process, independent of morphogenetic (shape) change, that is required for an animal organ to attain its fully functional state. An organ is a tissue or set of tissues that work together to perform a specific function or functions. http://purl.obolibrary.org/obo/UBERON_0035471 posterior surface of kidney http://purl.obolibrary.org/obo/UBERON_0036215 anatomical surface region http://purl.obolibrary.org/obo/NCBITaxon_4895 Schizosaccharomyces http://purl.obolibrary.org/obo/NCBITaxon_4894 Schizosaccharomycetaceae http://purl.obolibrary.org/obo/GO_0048820 hair follicle maturation http://purl.obolibrary.org/obo/GO_0071695 anatomical structure maturation A developmental process, independent of morphogenetic (shape) change, that is required for a hair follicle to attain its fully functional state. http://purl.obolibrary.org/obo/NCBITaxon_2605435 Evosea http://purl.obolibrary.org/obo/NCBITaxon_554915 Amoebozoa http://purl.obolibrary.org/obo/UBERON_0036288 anterior wall of left ventricle http://purl.obolibrary.org/obo/UBERON_0036285 wall of left ventricle http://purl.obolibrary.org/obo/GO_0048821 erythrocyte development http://purl.obolibrary.org/obo/GO_0061515 myeloid cell development The process whose specific outcome is the progression of an erythrocyte over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/CL_0000028 CNS neuron (sensu Nematoda and Protostomia) http://purl.obolibrary.org/obo/CL_2000029 central nervous system neuron http://purl.obolibrary.org/obo/CL_0000117 CNS neuron (sensu Vertebrata) http://purl.obolibrary.org/obo/CL_2000029 central nervous system neuron http://purl.obolibrary.org/obo/CL_0000379 sensory processing neuron http://purl.obolibrary.org/obo/CL_2000029 central nervous system neuron http://purl.obolibrary.org/obo/GO_0048822 enucleate erythrocyte development http://purl.obolibrary.org/obo/GO_0048821 erythrocyte development The process aimed at the progression of an enucleate erythrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. http://purl.obolibrary.org/obo/NCBITaxon_2301116 Rhabditina http://purl.obolibrary.org/obo/NCBITaxon_6236 Rhabditida http://purl.obolibrary.org/obo/NCBITaxon_9606 Homo sapiens http://purl.obolibrary.org/obo/NCBITaxon_9605 Homo http://purl.obolibrary.org/obo/GO_0048823 nucleate erythrocyte development http://purl.obolibrary.org/obo/GO_0048821 erythrocyte development The process aimed at the progression of a nucleate erythrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. http://purl.obolibrary.org/obo/NCBITaxon_338152 Felinae http://purl.obolibrary.org/obo/NCBITaxon_9681 Felidae http://purl.obolibrary.org/obo/CL_0000109 adrenergic neuron http://purl.obolibrary.org/obo/CL_4033050 catecholaminergic neuron http://purl.obolibrary.org/obo/GO_0048839 inner ear development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the inner ear over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0009154 purine ribonucleotide catabolic process http://purl.obolibrary.org/obo/GO_0009261 ribonucleotide catabolic process The chemical reactions and pathways resulting in the breakdown of a purine ribonucleotide, a compound consisting of ribonucleoside (a purine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. http://purl.obolibrary.org/obo/GO_0009165 nucleotide biosynthetic process http://purl.obolibrary.org/obo/GO_1901293 nucleoside phosphate biosynthetic process The chemical reactions and pathways resulting in the formation of nucleotides, any nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic-nucleotides (nucleoside cyclic phosphates). http://purl.obolibrary.org/obo/GO_0048844 artery morphogenesis http://purl.obolibrary.org/obo/GO_0048514 blood vessel morphogenesis The process in which the anatomical structures of arterial blood vessels are generated and organized. Arteries are blood vessels that transport blood from the heart to the body and its organs. http://purl.obolibrary.org/obo/GO_0009166 nucleotide catabolic process http://purl.obolibrary.org/obo/GO_1901292 nucleoside phosphate catabolic process The chemical reactions and pathways resulting in the breakdown of nucleotides, any nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic-nucleotides (nucleoside cyclic phosphates). http://purl.obolibrary.org/obo/GO_0009180 purine ribonucleoside diphosphate biosynthetic process http://purl.obolibrary.org/obo/GO_0009188 ribonucleoside diphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of purine ribonucleoside diphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with diphosphate on the sugar. http://purl.obolibrary.org/obo/GO_0048886 neuromast hair cell differentiation http://purl.obolibrary.org/obo/GO_0042490 mechanoreceptor differentiation The process in which a relatively unspecialized cell acquires specialized features of a neuromast hair cell. Hair cells are the sensory receptors of the neuromast and are located in a portion of the neuromast called the sensory strip. Each hair cell of the neuromast is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. There are approximately seven hair cells within each neuromast, with each hair cell innervated by afferent and efferent neurons. http://purl.obolibrary.org/obo/GO_0009206 purine ribonucleoside triphosphate biosynthetic process http://purl.obolibrary.org/obo/GO_0009205 purine ribonucleoside triphosphate metabolic process The chemical reactions and pathways resulting in the formation of purine ribonucleoside triphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with triphosphate on the sugar. http://purl.obolibrary.org/obo/GO_0009207 purine ribonucleoside triphosphate catabolic process http://purl.obolibrary.org/obo/GO_0009205 purine ribonucleoside triphosphate metabolic process The chemical reactions and pathways resulting in the breakdown of purine ribonucleoside triphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with triphosphate on the sugar. http://purl.obolibrary.org/obo/GO_0048903 anterior lateral line neuromast hair cell differentiation http://purl.obolibrary.org/obo/GO_0048886 neuromast hair cell differentiation The process in which a relatively unspecialized cell acquires specialized features of an anterior lateral line neuromast hair cell. Neuromast hair cells are the sensory receptors of the neuromast and are located in a portion of the neuromast called the sensory strip. Each hair cell of the neuromast is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. There are approximately seven hair cells within each neuromast, with each hair cell innervated by afferent and efferent neurons. http://purl.obolibrary.org/obo/GO_0009247 glycolipid biosynthetic process http://purl.obolibrary.org/obo/GO_1901137 carbohydrate derivative biosynthetic process The chemical reactions and pathways resulting in the formation of glycolipid, a class of 1,2-di-O-acylglycerols joined at oxygen 3 by a glycosidic linkage to a carbohydrate part (usually a mono-, di- or tri-saccharide). http://purl.obolibrary.org/obo/GO_0009250 glucan biosynthetic process http://purl.obolibrary.org/obo/GO_0000271 polysaccharide biosynthetic process The chemical reactions and pathways resulting in the formation of glucans, polysaccharides consisting only of glucose residues. http://purl.obolibrary.org/obo/GO_0048923 posterior lateral line neuromast hair cell differentiation http://purl.obolibrary.org/obo/GO_0048886 neuromast hair cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a posterior lateral line neuromast hair cell. (N.B. This may be development of neuromast hair cell type or a set of cell of neuromast hair cell type. This will involve the change of a cell or set of cells from one cell identity to another). Hair cells are the sensory receptors of the neuromast and are located in a portion of the neuromast called the sensory strip. Each hair cell of the neuromast is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. There are approximately seven hair cells within each neuromast, with each hair cell innervated by afferent and efferent neurons. http://purl.obolibrary.org/obo/GO_0009251 glucan catabolic process http://purl.obolibrary.org/obo/GO_0000272 polysaccharide catabolic process The chemical reactions and pathways resulting in the breakdown of glucans, polysaccharides consisting only of glucose residues. http://purl.obolibrary.org/obo/GO_0009416 response to light stimulus http://purl.obolibrary.org/obo/GO_0009314 response to radiation Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light. http://purl.obolibrary.org/obo/GO_0050000 chromosome localization http://purl.obolibrary.org/obo/GO_0051640 organelle localization Any process in which a chromosome is transported to, or maintained in, a specific location. http://purl.obolibrary.org/obo/GO_0009566 fertilization http://purl.obolibrary.org/obo/GO_0022414 reproductive process The union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy). http://purl.obolibrary.org/obo/GO_0009583 detection of light stimulus http://purl.obolibrary.org/obo/GO_0009582 detection of abiotic stimulus The series of events in which a light stimulus (in the form of photons) is received and converted into a molecular signal. http://purl.obolibrary.org/obo/GO_0050746 regulation of lipoprotein metabolic process http://purl.obolibrary.org/obo/GO_0051246 regulation of protein metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving lipoproteins, any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids. http://purl.obolibrary.org/obo/GO_0009584 detection of visible light http://purl.obolibrary.org/obo/GO_0009583 detection of light stimulus The series of events in which a visible light stimulus is received by a cell and converted into a molecular signal. A visible light stimulus is electromagnetic radiation that can be perceived visually by an organism; for organisms lacking a visual system, this can be defined as light with a wavelength within the range 380 to 780 nm. http://purl.obolibrary.org/obo/GO_0009589 detection of UV http://purl.obolibrary.org/obo/GO_0009411 response to UV The series of events in which an ultraviolet radiation (UV light) stimulus is received and converted into a molecular signal. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers. http://purl.obolibrary.org/obo/GO_0050748 negative regulation of lipoprotein metabolic process http://purl.obolibrary.org/obo/GO_0050746 regulation of lipoprotein metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving lipoproteins, any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids. http://purl.obolibrary.org/obo/GO_0009612 response to mechanical stimulus http://purl.obolibrary.org/obo/GO_0009605 response to external stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mechanical stimulus. http://purl.obolibrary.org/obo/GO_0009628 response to abiotic stimulus http://purl.obolibrary.org/obo/GO_0050896 response to stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (not derived from living organisms) stimulus. http://purl.obolibrary.org/obo/GO_0050772 positive regulation of axonogenesis http://purl.obolibrary.org/obo/GO_0031346 positive regulation of cell projection organization Any process that activates or increases the frequency, rate or extent of axonogenesis. http://purl.obolibrary.org/obo/GO_0009712 catechol-containing compound metabolic process http://purl.obolibrary.org/obo/GO_0018958 phenol-containing compound metabolic process The chemical reactions and pathways involving a compound containing a pyrocatechol (1,2-benzenediol) nucleus or substituent. http://purl.obolibrary.org/obo/GO_0009948 anterior/posterior axis specification http://purl.obolibrary.org/obo/GO_0009798 axis specification The establishment, maintenance and elaboration of the anterior/posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism. http://purl.obolibrary.org/obo/GO_0050840 extracellular matrix binding http://purl.obolibrary.org/obo/GO_0005488 binding Binding to a component of the extracellular matrix. http://purl.obolibrary.org/obo/GO_0010004 gastrulation involving germ band extension http://purl.obolibrary.org/obo/GO_0001703 gastrulation with mouth forming first A complex and coordinated series of cellular movements, including germ band extension, that occurs at the end of cleavage during embryonic development. An example of this process is found in Drosophila melanogaster. http://purl.obolibrary.org/obo/GO_0010160 formation of animal organ boundary http://purl.obolibrary.org/obo/GO_0003002 regionalization The regionalization process that specifies animal organ primordium boundaries resulting in a restriction of organogenesis to a limited spatial domain and keeping the organ separate from surrounding tissues. http://purl.obolibrary.org/obo/GO_0050863 regulation of T cell activation http://purl.obolibrary.org/obo/GO_0051249 regulation of lymphocyte activation Any process that modulates the frequency, rate or extent of T cell activation. http://purl.obolibrary.org/obo/GO_0010256 endomembrane system organization http://purl.obolibrary.org/obo/GO_0016043 cellular component organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endomembrane system. http://purl.obolibrary.org/obo/GO_0050868 negative regulation of T cell activation http://purl.obolibrary.org/obo/GO_0050863 regulation of T cell activation Any process that stops, prevents, or reduces the frequency, rate or extent of T cell activation. http://purl.obolibrary.org/obo/GO_0010324 membrane invagination http://purl.obolibrary.org/obo/GO_0061024 membrane organization The infolding of a membrane. http://purl.obolibrary.org/obo/GO_0050932 regulation of pigment cell differentiation http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the frequency, rate or extent of pigmented cell differentiation. http://purl.obolibrary.org/obo/GO_0010469 regulation of signaling receptor activity http://purl.obolibrary.org/obo/GO_0065009 regulation of molecular function Any process that modulates the frequency, rate or extent of a signaling receptor activity. Receptor activity is when a molecule combines with an extracellular or intracellular messenger to initiate a change in cell activity. http://purl.obolibrary.org/obo/GO_0050941 negative regulation of pigment cell differentiation http://purl.obolibrary.org/obo/GO_0050932 regulation of pigment cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of pigment cell differentiation. http://purl.obolibrary.org/obo/GO_0010564 regulation of cell cycle process http://purl.obolibrary.org/obo/GO_0051726 regulation of cell cycle Any process that modulates a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. http://purl.obolibrary.org/obo/GO_0050942 positive regulation of pigment cell differentiation http://purl.obolibrary.org/obo/GO_0045597 positive regulation of cell differentiation Any process that activates or increases the frequency, rate or extent of pigment cell differentiation. http://purl.obolibrary.org/obo/GO_0010565 regulation of ketone metabolic process http://purl.obolibrary.org/obo/GO_0019222 regulation of metabolic process Any process that modulates the chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups. http://purl.obolibrary.org/obo/GO_0051098 regulation of binding http://purl.obolibrary.org/obo/GO_0065009 regulation of molecular function Any process that modulates the frequency, rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule. http://purl.obolibrary.org/obo/GO_0051101 regulation of DNA binding http://purl.obolibrary.org/obo/GO_0051098 regulation of binding Any process that modulates the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid). http://purl.obolibrary.org/obo/GO_0010566 regulation of ketone biosynthetic process http://purl.obolibrary.org/obo/GO_0009889 regulation of biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of a ketone, carried out by individual cells. http://purl.obolibrary.org/obo/GO_0010608 post-transcriptional regulation of gene expression http://purl.obolibrary.org/obo/GO_0010468 regulation of gene expression Any process that modulates the frequency, rate or extent of gene expression after the production of an RNA transcript. http://purl.obolibrary.org/obo/GO_0051145 smooth muscle cell differentiation http://purl.obolibrary.org/obo/GO_0042692 muscle cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell; smooth muscle lacks transverse striations in its constituent fibers and are almost always involuntary. http://purl.obolibrary.org/obo/GO_0010629 negative regulation of gene expression http://purl.obolibrary.org/obo/GO_0010558 negative regulation of macromolecule biosynthetic process Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA). http://purl.obolibrary.org/obo/GO_0051147 regulation of muscle cell differentiation http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the frequency, rate or extent of muscle cell differentiation. http://purl.obolibrary.org/obo/GO_0051148 negative regulation of muscle cell differentiation http://purl.obolibrary.org/obo/GO_0051147 regulation of muscle cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of muscle cell differentiation. http://purl.obolibrary.org/obo/GO_0010631 epithelial cell migration http://purl.obolibrary.org/obo/GO_0001667 ameboidal-type cell migration The orderly movement of an epithelial cell from one site to another, often during the development of a multicellular organism. http://purl.obolibrary.org/obo/GO_0010876 lipid localization http://purl.obolibrary.org/obo/GO_0033036 macromolecule localization Any process in which a lipid is transported to, or maintained in, a specific location. http://purl.obolibrary.org/obo/GO_0051149 positive regulation of muscle cell differentiation http://purl.obolibrary.org/obo/GO_0045597 positive regulation of cell differentiation Any process that activates or increases the frequency, rate or extent of muscle cell differentiation. http://purl.obolibrary.org/obo/GO_0010906 regulation of glucose metabolic process http://purl.obolibrary.org/obo/GO_0062012 regulation of small molecule metabolic process Any process that modulates the rate, frequency or extent of glucose metabolism. Glucose metabolic processes are the chemical reactions and pathways involving glucose, the aldohexose gluco-hexose. http://purl.obolibrary.org/obo/GO_0051222 positive regulation of protein transport http://purl.obolibrary.org/obo/GO_0051050 positive regulation of transport Any process that activates or increases the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0010962 regulation of glucan biosynthetic process http://purl.obolibrary.org/obo/GO_0032885 regulation of polysaccharide biosynthetic process Any process that modulates the rate, frequency, or extent of glucan biosynthesis. Glucan biosynthetic processes are the chemical reactions and pathways resulting in the formation of glucans, polysaccharides consisting only of glucose residues. http://purl.obolibrary.org/obo/GO_0051224 negative regulation of protein transport http://purl.obolibrary.org/obo/GO_1903828 negative regulation of protein localization Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0010970 transport along microtubule http://purl.obolibrary.org/obo/GO_0099111 microtubule-based transport The movement of organelles or other particles from one location in the cell to another along microtubules, driven by motor activity. http://purl.obolibrary.org/obo/GO_0051338 regulation of transferase activity http://purl.obolibrary.org/obo/GO_0050790 regulation of catalytic activity Any process that modulates the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2. http://purl.obolibrary.org/obo/GO_0012505 endomembrane system http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles. http://purl.obolibrary.org/obo/GO_0051402 neuron apoptotic process http://purl.obolibrary.org/obo/GO_0006915 apoptotic process Any apoptotic process in a neuron, the basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system. http://purl.obolibrary.org/obo/GO_0014902 myotube differentiation http://purl.obolibrary.org/obo/GO_0051146 striated muscle cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotube differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual myotubes can fuse to form bigger myotubes and start to contract. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse. http://purl.obolibrary.org/obo/GO_0051445 regulation of meiotic cell cycle http://purl.obolibrary.org/obo/GO_2000241 regulation of reproductive process Any process that modulates the rate or extent of progression through the meiotic cell cycle. http://purl.obolibrary.org/obo/GO_0051446 positive regulation of meiotic cell cycle http://purl.obolibrary.org/obo/GO_2000243 positive regulation of reproductive process Any process that activates or increases the frequency, rate or extent of progression through the meiotic cell cycle. http://purl.obolibrary.org/obo/GO_0015031 protein transport http://purl.obolibrary.org/obo/GO_0045184 establishment of protein localization The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0051447 negative regulation of meiotic cell cycle http://purl.obolibrary.org/obo/GO_2000242 negative regulation of reproductive process Any process that stops, prevents or reduces the rate or extent of progression through the meiotic cell cycle. http://purl.obolibrary.org/obo/GO_0015075 monoatomic ion transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity Enables the transfer of an ion from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0051469 vesicle fusion with vacuole http://purl.obolibrary.org/obo/GO_0097576 vacuole fusion The joining of the lipid bilayer membrane around a vesicle with the lipid bilayer membrane around the vacuole. http://purl.obolibrary.org/obo/GO_0015079 potassium ion transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0046873 metal ion transmembrane transporter activity Enables the transfer of potassium ions (K+) from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0051654 establishment of mitochondrion localization http://purl.obolibrary.org/obo/GO_0051656 establishment of organelle localization The directed movement of the mitochondrion to a specific location. http://purl.obolibrary.org/obo/GO_0015081 sodium ion transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0046873 metal ion transmembrane transporter activity Enables the transfer of sodium ions (Na+) from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0051658 maintenance of nucleus location http://purl.obolibrary.org/obo/GO_0051647 nucleus localization Any process in which the nucleus is maintained in a specific location within a cell and prevented from moving elsewhere. http://purl.obolibrary.org/obo/GO_0015085 calcium ion transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0046873 metal ion transmembrane transporter activity Enables the transfer of calcium (Ca) ions from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0051890 regulation of cardioblast differentiation http://purl.obolibrary.org/obo/GO_2000736 regulation of stem cell differentiation Any process that modulates the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. http://purl.obolibrary.org/obo/GO_0015149 hexose transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0015145 monosaccharide transmembrane transporter activity Enables the transfer of a hexose sugar, a monosaccharide with 6 carbon atoms, from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0015172 acidic amino acid transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0015171 amino acid transmembrane transporter activity Enables the transfer of acidic amino acids from one side of a membrane to the other. Acidic amino acids have side chains with a negative charge at pH 7.3. http://purl.obolibrary.org/obo/GO_0051930 regulation of sensory perception of pain http://purl.obolibrary.org/obo/GO_0051931 regulation of sensory perception Any process that modulates the frequency, rate or extent of the sensory perception of pain, the series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal. http://purl.obolibrary.org/obo/GO_0015173 aromatic amino acid transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0046943 carboxylic acid transmembrane transporter activity Enables the transfer of aromatic amino acids from one side of a membrane to the other. Aromatic amino acids have an aromatic ring. http://purl.obolibrary.org/obo/GO_0051969 regulation of transmission of nerve impulse http://purl.obolibrary.org/obo/GO_0031644 regulation of nervous system process Any process that modulates the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation. http://purl.obolibrary.org/obo/GO_0015174 basic amino acid transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0015171 amino acid transmembrane transporter activity Enables the transfer of basic amino acids from one side of a membrane to the other. Basic amino acids have side chains with a positive charge at pH 7.3. http://purl.obolibrary.org/obo/GO_0055059 asymmetric neuroblast division http://purl.obolibrary.org/obo/GO_0055057 neuroblast division The process resulting in the physical partitioning and separation of a neuroblast into two daughter cells with different developmental potentials. http://purl.obolibrary.org/obo/GO_0015185 gamma-aminobutyric acid transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0015171 amino acid transmembrane transporter activity Enables the transfer of gamma-aminobutyric acid from one side of a membrane to the other. Gamma-aminobutyric acid is 4-aminobutyrate (GABA). http://purl.obolibrary.org/obo/GO_0060065 uterus development http://purl.obolibrary.org/obo/GO_0048608 reproductive structure development The reproductive developmental process whose specific outcome is the progression of the uterus over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0015215 nucleotide transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0015605 organophosphate ester transmembrane transporter activity Enables the transfer of a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate, from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0060066 oviduct development http://purl.obolibrary.org/obo/GO_0048608 reproductive structure development The reproductive developmental process whose specific outcome is the progression of an oviduct over time, from its formation to the mature structure. An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism. http://purl.obolibrary.org/obo/GO_0015217 ADP transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0000295 adenine nucleotide transmembrane transporter activity Enables the transfer of ADP, adenosine diphosphate, from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0015245 fatty acid transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0170055 lipid transmembrane transporter activity Enables the transfer of fatty acids from one side of a membrane to the other. Fatty acids are aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis. http://purl.obolibrary.org/obo/GO_0060113 inner ear receptor cell differentiation http://purl.obolibrary.org/obo/GO_0042490 mechanoreceptor differentiation The process in which relatively unspecialized cells, acquire specialized structural and/or functional features of inner ear receptor cells. Inner ear receptor cells are mechanorecptors found in the inner ear responsible for transducing signals involved in balance and sensory perception of sound. http://purl.obolibrary.org/obo/GO_0015276 ligand-gated monoatomic ion channel activity http://purl.obolibrary.org/obo/GO_0022834 ligand-gated channel activity Enables the transmembrane transfer of an ion by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts. http://purl.obolibrary.org/obo/GO_0060173 limb development http://purl.obolibrary.org/obo/GO_0048736 appendage development The process whose specific outcome is the progression of a limb over time, from its formation to the mature structure. A limb is an appendage of an animal used for locomotion or grasping. Examples include legs, arms or some types of fin. http://purl.obolibrary.org/obo/GO_0015631 tubulin binding http://purl.obolibrary.org/obo/GO_0008092 cytoskeletal protein binding Binding to monomeric or multimeric forms of tubulin, including microtubules. http://purl.obolibrary.org/obo/GO_0060174 limb bud formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process pertaining to the initial formation of a limb bud from unspecified parts. This process begins with the formation of a local condensation of mesenchyme cells within the prospective limb field, and ends when a limb bud is recognizable. http://purl.obolibrary.org/obo/GO_0015671 oxygen transport http://purl.obolibrary.org/obo/GO_0015669 gas transport The directed movement of oxygen (O2) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0015718 monocarboxylic acid transport http://purl.obolibrary.org/obo/GO_0046942 carboxylic acid transport The directed movement of monocarboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0060219 camera-type eye photoreceptor cell differentiation http://purl.obolibrary.org/obo/GO_0001754 eye photoreceptor cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a photoreceptor cell in a camera-type eye. http://purl.obolibrary.org/obo/GO_0060271 cilium assembly http://purl.obolibrary.org/obo/GO_0120031 plasma membrane bounded cell projection assembly The assembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole. http://purl.obolibrary.org/obo/GO_0015837 amine transport http://purl.obolibrary.org/obo/GO_0071705 nitrogen compound transport The directed movement of amines, including polyamines, organic compounds containing one or more amino groups, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0015844 monoamine transport http://purl.obolibrary.org/obo/GO_0071705 nitrogen compound transport The directed movement of monoamines, organic compounds that contain one amino group that is connected to an aromatic ring by an ethylene group (-CH2-CH2-), into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0060348 bone development http://purl.obolibrary.org/obo/GO_0048513 animal organ development The process whose specific outcome is the progression of bone over time, from its formation to the mature structure. Bone is the hard skeletal connective tissue consisting of both mineral and cellular components. http://purl.obolibrary.org/obo/GO_0015850 organic hydroxy compound transport http://purl.obolibrary.org/obo/GO_0006810 transport The directed movement of an organic hydroxy compound (organic alcohol) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. An organic hydroxy compound is an organic compound having at least one hydroxy group attached to a carbon atom. http://purl.obolibrary.org/obo/GO_0060359 response to ammonium ion http://purl.obolibrary.org/obo/GO_1901698 response to nitrogen compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ammonium stimulus. http://purl.obolibrary.org/obo/GO_0060465 pharynx development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The biological process whose specific outcome is the progression of a pharynx from an initial condition to its mature state. The pharynx is the part of the digestive system immediately posterior to the mouth. http://purl.obolibrary.org/obo/GO_0015867 ATP transport http://purl.obolibrary.org/obo/GO_0015868 purine ribonucleotide transport The directed movement of ATP, adenosine triphosphate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0015931 nucleobase-containing compound transport http://purl.obolibrary.org/obo/GO_0071705 nitrogen compound transport The directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0060467 negative regulation of fertilization http://purl.obolibrary.org/obo/GO_2000242 negative regulation of reproductive process Any process that decreases the rate, frequency or extent of fertilization. Fertilization is the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy). http://purl.obolibrary.org/obo/GO_0015932 nucleobase-containing compound transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity Enables the transfer of nucleobases, nucleosides, nucleotides and nucleic acids from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0060581 cell fate commitment involved in pattern specification http://purl.obolibrary.org/obo/GO_0045165 cell fate commitment The commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells within a field of cells that will exhibit a certain pattern of differentiation. Positional information is established through protein signals that emanate from a localized source within a developmental field resulting in specification of a cell type. Those signals are then interpreted in a cell-autonomous manner resulting in the determination of the cell type. http://purl.obolibrary.org/obo/GO_0015980 energy derivation by oxidation of organic compounds http://purl.obolibrary.org/obo/GO_0006091 generation of precursor metabolites and energy The chemical reactions and pathways by which a cell derives energy from organic compounds; results in the oxidation of the compounds from which energy is released. http://purl.obolibrary.org/obo/GO_0016020 membrane http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. http://purl.obolibrary.org/obo/GO_0060840 artery development http://purl.obolibrary.org/obo/GO_0001568 blood vessel development The progression of the artery over time, from its initial formation to the mature structure. An artery is a blood vessel that carries blood away from the heart to a capillary bed. http://purl.obolibrary.org/obo/GO_0016042 lipid catabolic process http://purl.obolibrary.org/obo/GO_0009056 catabolic process The chemical reactions and pathways resulting in the breakdown of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. http://purl.obolibrary.org/obo/GO_0061005 cell differentiation involved in kidney development http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the kidney as it progresses from its formation to the mature state. http://purl.obolibrary.org/obo/GO_0016043 cellular component organization http://purl.obolibrary.org/obo/GO_0071840 cellular component organization or biogenesis A process that results in the assembly, arrangement of constituent parts, or disassembly of a cellular component. http://purl.obolibrary.org/obo/GO_0061009 common bile duct development http://purl.obolibrary.org/obo/GO_0035295 tube development The progression of the common bile duct over time, from its formation to the mature structure. The common bile duct is formed from the joining of the common hepatic duct running from the liver, and the cystic duct running from the gallbladder. The common bile duct transports bile from the liver and gallbladder to the intestine. http://purl.obolibrary.org/obo/GO_0016106 sesquiterpenoid biosynthetic process http://purl.obolibrary.org/obo/GO_0016114 terpenoid biosynthetic process The chemical reactions and pathways resulting in the formation of sesquiterpenoid compounds, terpenoids with three isoprene units. http://purl.obolibrary.org/obo/GO_0016107 sesquiterpenoid catabolic process http://purl.obolibrary.org/obo/GO_0016115 terpenoid catabolic process The chemical reactions and pathways resulting in the breakdown of sesquiterpenoid compounds, terpenoids with three isoprene units. http://purl.obolibrary.org/obo/GO_0061027 umbilical cord development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the development of the umbilical cord, from its formation to the mature structure. The umbilical cord is an organ or embryonic origin consisting of the 2 umbilical arteries and the one umbilical vein. The umbilical cord connects the cardiovascular system of the fetus to the mother via the placenta. http://purl.obolibrary.org/obo/GO_0016192 vesicle-mediated transport http://purl.obolibrary.org/obo/GO_0009987 cellular process A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane. http://purl.obolibrary.org/obo/GO_0061178 regulation of insulin secretion involved in cellular response to glucose stimulus http://purl.obolibrary.org/obo/GO_0060341 regulation of cellular localization Any process that modulates the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose. http://purl.obolibrary.org/obo/GO_0016325 oocyte microtubule cytoskeleton organization http://purl.obolibrary.org/obo/GO_0030951 establishment or maintenance of microtubule cytoskeleton polarity Formation and maintenance of a polarized microtubule array originating from a microtubule-organizing center (MTOC) in the oocyte. An example of this is found in Drosophila melanogaster. http://purl.obolibrary.org/obo/GO_0061303 cornea development in camera-type eye http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the cornea over time, from its formation to the mature structure. The cornea is the transparent structure that covers the anterior of the eye. http://purl.obolibrary.org/obo/GO_0061469 regulation of type B pancreatic cell proliferation http://purl.obolibrary.org/obo/GO_0050678 regulation of epithelial cell proliferation Any process that modulates the frequency, rate or extent of type B pancreatic cell proliferation. http://purl.obolibrary.org/obo/GO_0016482 cytosolic transport http://purl.obolibrary.org/obo/GO_0046907 intracellular transport The directed movement of substances or organelles within the cytosol. http://purl.obolibrary.org/obo/GO_0016595 glutamate binding http://purl.obolibrary.org/obo/GO_0016597 amino acid binding Binding to glutamate, the anion of 2-aminopentanedioic acid. http://purl.obolibrary.org/obo/GO_0070026 nitric oxide binding http://purl.obolibrary.org/obo/GO_0036094 small molecule binding Binding to nitric oxide (NO). http://purl.obolibrary.org/obo/GO_0070286 axonemal dynein complex assembly http://purl.obolibrary.org/obo/GO_0065003 protein-containing complex assembly The aggregation, arrangement and bonding together of a set of components to form an axonemal dynein complex, a dynein complex found in eukaryotic cilia and flagella, in which the motor domain heads interact with adjacent microtubules to generate a sliding force which is converted to a bending motion. http://purl.obolibrary.org/obo/GO_0016907 G protein-coupled acetylcholine receptor activity http://purl.obolibrary.org/obo/GO_0099528 G protein-coupled neurotransmitter receptor activity Combining with acetylcholine and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. http://purl.obolibrary.org/obo/GO_0016917 GABA receptor activity http://purl.obolibrary.org/obo/GO_0004888 transmembrane signaling receptor activity Combining with gamma-aminobutyric acid (GABA), and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. (GABA, 4-aminobutyrate) is an amino acid which acts as a neurotransmitter in some organisms. http://purl.obolibrary.org/obo/GO_0070293 renal absorption http://purl.obolibrary.org/obo/GO_0003014 renal system process A renal system process in which water, ions, glucose and proteins are taken up from the collecting ducts, glomerulus and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures (e.g. protein absorption is observed in nephrocytes in Drosophila, see PMID:23264686). http://purl.obolibrary.org/obo/GO_0017148 negative regulation of translation http://purl.obolibrary.org/obo/GO_0051248 negative regulation of protein metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA. http://purl.obolibrary.org/obo/GO_0070295 renal water absorption http://purl.obolibrary.org/obo/GO_0070293 renal absorption A renal system process in which water is taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures. http://purl.obolibrary.org/obo/GO_0070509 calcium ion import http://purl.obolibrary.org/obo/GO_0006816 calcium ion transport The directed movement of calcium ions into a cell or organelle. http://purl.obolibrary.org/obo/GO_0018958 phenol-containing compound metabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process The chemical reactions and pathways involving a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring. http://purl.obolibrary.org/obo/GO_0070840 dynein complex binding http://purl.obolibrary.org/obo/GO_0044877 protein-containing complex binding Binding to a dynein complex, a protein complex that contains two or three dynein heavy chains and several light chains, and has microtubule motor activity. http://purl.obolibrary.org/obo/GO_0019098 reproductive behavior http://purl.obolibrary.org/obo/GO_0007610 behavior The specific behavior of an organism that is associated with reproduction. http://purl.obolibrary.org/obo/GO_0019217 regulation of fatty acid metabolic process http://purl.obolibrary.org/obo/GO_0019216 regulation of lipid metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving fatty acids. http://purl.obolibrary.org/obo/GO_0070874 negative regulation of glycogen metabolic process http://purl.obolibrary.org/obo/GO_0045912 negative regulation of carbohydrate metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving glycogen. http://purl.obolibrary.org/obo/GO_0019218 regulation of steroid metabolic process http://purl.obolibrary.org/obo/GO_0019216 regulation of lipid metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving steroids. http://purl.obolibrary.org/obo/GO_0070875 positive regulation of glycogen metabolic process http://purl.obolibrary.org/obo/GO_0010907 positive regulation of glucose metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving glycogen. http://purl.obolibrary.org/obo/GO_0019219 regulation of nucleobase-containing compound metabolic process http://purl.obolibrary.org/obo/GO_0080090 regulation of primary metabolic process Any cellular process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids. http://purl.obolibrary.org/obo/GO_0070977 bone maturation http://purl.obolibrary.org/obo/GO_0048799 animal organ maturation A developmental process, independent of morphogenetic (shape) change, that is required for bone to attain its fully functional state. http://purl.obolibrary.org/obo/GO_0019318 hexose metabolic process http://purl.obolibrary.org/obo/GO_0005996 monosaccharide metabolic process The chemical reactions and pathways involving a hexose, any monosaccharide with a chain of six carbon atoms in the molecule. http://purl.obolibrary.org/obo/GO_0019319 hexose biosynthetic process http://purl.obolibrary.org/obo/GO_0046364 monosaccharide biosynthetic process The chemical reactions and pathways resulting in the formation of hexose, any monosaccharide with a chain of six carbon atoms in the molecule. http://purl.obolibrary.org/obo/GO_0071230 cellular response to amino acid stimulus http://purl.obolibrary.org/obo/GO_0071229 cellular response to acid chemical Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups. http://purl.obolibrary.org/obo/GO_0019320 hexose catabolic process http://purl.obolibrary.org/obo/GO_0046365 monosaccharide catabolic process The chemical reactions and pathways resulting in the breakdown of hexose, any monosaccharide with a chain of six carbon atoms in the molecule. http://purl.obolibrary.org/obo/GO_0071242 cellular response to ammonium ion http://purl.obolibrary.org/obo/GO_1901699 cellular response to nitrogen compound Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ammonium stimulus. http://purl.obolibrary.org/obo/GO_0019538 protein metabolic process http://purl.obolibrary.org/obo/GO_0044238 primary metabolic process The chemical reactions and pathways involving a protein. Includes protein modification. http://purl.obolibrary.org/obo/GO_0071281 cellular response to iron ion http://purl.obolibrary.org/obo/GO_0010039 response to iron ion Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron ion stimulus. http://purl.obolibrary.org/obo/GO_0019637 organophosphate metabolic process http://purl.obolibrary.org/obo/GO_0006793 phosphorus metabolic process The chemical reactions and pathways involving organophosphates, any phosphate-containing organic compound. http://purl.obolibrary.org/obo/GO_0071383 cellular response to steroid hormone stimulus http://purl.obolibrary.org/obo/GO_0032870 cellular response to hormone stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a steroid hormone stimulus. http://purl.obolibrary.org/obo/GO_0019693 ribose phosphate metabolic process http://purl.obolibrary.org/obo/GO_1901135 carbohydrate derivative metabolic process The chemical reactions and pathways involving ribose phosphate, any phosphorylated ribose sugar. http://purl.obolibrary.org/obo/GO_0071385 cellular response to glucocorticoid stimulus http://purl.obolibrary.org/obo/GO_0071384 cellular response to corticosteroid stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucocorticoid stimulus. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects. http://purl.obolibrary.org/obo/GO_0019722 calcium-mediated signaling http://purl.obolibrary.org/obo/GO_0141124 intracellular signaling cassette Any intracellular signal transduction in which the signal is passed on within the cell via calcium ions. http://purl.obolibrary.org/obo/GO_0019725 cellular homeostasis http://purl.obolibrary.org/obo/GO_0042592 homeostatic process Any process involved in the maintenance of an internal steady state at the level of the cell. http://purl.obolibrary.org/obo/GO_0071396 cellular response to lipid http://purl.obolibrary.org/obo/GO_0033993 response to lipid Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid stimulus. http://purl.obolibrary.org/obo/GO_0019747 regulation of isoprenoid metabolic process http://purl.obolibrary.org/obo/GO_0019216 regulation of lipid metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving isoprenoids. http://purl.obolibrary.org/obo/GO_0019752 carboxylic acid metabolic process http://purl.obolibrary.org/obo/GO_0043436 oxoacid metabolic process The chemical reactions and pathways involving carboxylic acids, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-). http://purl.obolibrary.org/obo/GO_0071418 cellular response to amine stimulus http://purl.obolibrary.org/obo/GO_1901699 cellular response to nitrogen compound Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amine stimulus. An amine is a compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups. http://purl.obolibrary.org/obo/GO_0019840 isoprenoid binding http://purl.obolibrary.org/obo/GO_0008289 lipid binding Binding to an isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues. http://purl.obolibrary.org/obo/GO_0071462 cellular response to water stimulus http://purl.obolibrary.org/obo/GO_0071229 cellular response to acid chemical Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of water. http://purl.obolibrary.org/obo/GO_0021700 developmental maturation http://purl.obolibrary.org/obo/GO_0032502 developmental process A developmental process, independent of morphogenetic (shape) change, that is required for an anatomical structure, cell or cellular component to attain its fully functional state. http://purl.obolibrary.org/obo/GO_0071692 protein localization to extracellular region http://purl.obolibrary.org/obo/GO_0033036 macromolecule localization Any process in which a protein is transported from one specific location in the extracellular region to another, or maintained in a specific extracellular location. http://purl.obolibrary.org/obo/GO_0022404 molting cycle process http://purl.obolibrary.org/obo/GO_0032501 multicellular organismal process A multicellular organismal process involved in the periodic casting off and regeneration of an outer covering of cuticle, feathers, hair, horns, skin. http://purl.obolibrary.org/obo/GO_0071711 basement membrane organization http://purl.obolibrary.org/obo/GO_0030198 extracellular matrix organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the basement membrane. http://purl.obolibrary.org/obo/GO_0022411 cellular component disassembly http://purl.obolibrary.org/obo/GO_0016043 cellular component organization A cellular process that results in the breakdown of a cellular component. http://purl.obolibrary.org/obo/GO_0071731 response to nitric oxide http://purl.obolibrary.org/obo/GO_1901698 response to nitrogen compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitric oxide stimulus. http://purl.obolibrary.org/obo/GO_0022612 gland morphogenesis http://purl.obolibrary.org/obo/GO_0009887 animal organ morphogenesis The process in which the anatomical structures of a gland are generated and organized. http://purl.obolibrary.org/obo/GO_0071867 response to monoamine http://purl.obolibrary.org/obo/GO_1901698 response to nitrogen compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monoamine stimulus. A monoamine is any of a group of molecular messengers that contain one amino group that is connected to an aromatic ring by ethylene group (-CH2-CH2-). Monoamines are derived from the aromatic amino acids phenylalanine, tyrosine, histidine and tryptophan. http://purl.obolibrary.org/obo/GO_0022626 cytosolic ribosome http://purl.obolibrary.org/obo/GO_0005840 ribosome A ribosome located in the cytosol. http://purl.obolibrary.org/obo/GO_0022824 transmitter-gated monoatomic ion channel activity http://purl.obolibrary.org/obo/GO_0022835 transmitter-gated channel activity Enables the transmembrane transfer of an ion by a channel that opens when a specific neurotransmitter has been bound by the channel complex or one of its constituent parts. http://purl.obolibrary.org/obo/GO_0072014 proximal tubule development http://purl.obolibrary.org/obo/GO_0072080 nephron tubule development The process whose specific outcome is the progression of the proximal tubule over time, from its formation to the mature structure. In mammals, the proximal tubule is a nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle. It has a brush border epithelial morphology. http://purl.obolibrary.org/obo/GO_0022832 voltage-gated channel activity http://purl.obolibrary.org/obo/GO_0022836 gated channel activity Enables the transmembrane transfer of a solute by a channel whose open state is dependent on the voltage across the membrane in which it is embedded. http://purl.obolibrary.org/obo/GO_0072017 distal tubule development http://purl.obolibrary.org/obo/GO_0072080 nephron tubule development The process whose specific outcome is the progression of the distal tubule over time, from its formation to the mature structure. In mammals, the distal tubule is a nephron tubule that begins at the macula densa and extends to the connecting tubule. http://purl.obolibrary.org/obo/GO_0022839 monoatomic ion-gated channel activity http://purl.obolibrary.org/obo/GO_0022834 ligand-gated channel activity Enables the transmembrane transfer of a solute by a channel that opens in response to a specific ion stimulus. http://purl.obolibrary.org/obo/GO_0022843 voltage-gated monoatomic cation channel activity http://purl.obolibrary.org/obo/GO_0005261 monoatomic cation channel activity Enables the transmembrane transfer of a cation by a voltage-gated channel. A cation is a positively charged ion. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. http://purl.obolibrary.org/obo/GO_0072028 nephron morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structures of the nephron are generated and organized. A nephron is the functional unit of the kidney. http://purl.obolibrary.org/obo/GO_0022848 acetylcholine-gated monoatomic cation-selective channel activity http://purl.obolibrary.org/obo/GO_0098960 postsynaptic neurotransmitter receptor activity Selectively enables the transmembrane transfer of a cation by a channel that opens upon binding acetylcholine. http://purl.obolibrary.org/obo/GO_0072078 nephron tubule morphogenesis http://purl.obolibrary.org/obo/GO_0072088 nephron epithelium morphogenesis The process in which the anatomical structures of a nephron tubule are generated and organized. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney. http://purl.obolibrary.org/obo/GO_0022850 serotonin-gated monoatomic cation channel activity http://purl.obolibrary.org/obo/GO_0099589 serotonin receptor activity Enables the transmembrane transfer of a cation by a channel that opens when serotonin has been bound by the channel complex or one of its constituent parts. http://purl.obolibrary.org/obo/GO_0072079 nephron tubule formation http://purl.obolibrary.org/obo/GO_0001838 embryonic epithelial tube formation The developmental process pertaining to the initial formation of a nephron tubule from unspecified parts. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney. http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0005215 transporter activity Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0072080 nephron tubule development http://purl.obolibrary.org/obo/GO_0072009 nephron epithelium development The progression of a nephron tubule over time, from its initial formation to the mature structure. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney. http://purl.obolibrary.org/obo/GO_0072102 glomerulus morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structures of the glomerulus are generated and organized. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney. http://purl.obolibrary.org/obo/GO_0030003 intracellular monoatomic cation homeostasis http://purl.obolibrary.org/obo/GO_0055080 monoatomic cation homeostasis A homeostatic process involved in the maintenance of a steady state level of monoatomic cations within a cell. Monatomic cations (also called simple cations) are cations consisting of exactly one atom. http://purl.obolibrary.org/obo/GO_0072111 cell proliferation involved in kidney development http://purl.obolibrary.org/obo/GO_0008283 cell population proliferation The multiplication or reproduction of cells, resulting in the expansion of the population in the kidney. http://purl.obolibrary.org/obo/GO_0030017 sarcomere http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure The repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs. http://purl.obolibrary.org/obo/GO_0072114 pronephros morphogenesis http://purl.obolibrary.org/obo/GO_0060993 kidney morphogenesis The process in which the anatomical structures of the pronephros are generated and organized. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life. http://purl.obolibrary.org/obo/GO_0030031 cell projection assembly http://purl.obolibrary.org/obo/GO_0030030 cell projection organization Formation of a prolongation or process extending from a cell, e.g. a flagellum or axon. http://purl.obolibrary.org/obo/GO_0072116 pronephros formation http://purl.obolibrary.org/obo/GO_0072003 kidney rudiment formation The developmental process pertaining to the initial formation of the pronephros. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life. http://purl.obolibrary.org/obo/GO_0030036 actin cytoskeleton organization http://purl.obolibrary.org/obo/GO_0030029 actin filament-based process A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins. http://purl.obolibrary.org/obo/GO_0072156 distal tubule morphogenesis http://purl.obolibrary.org/obo/GO_0072078 nephron tubule morphogenesis The process in which the anatomical structures of a distal tubule are generated and organized. The distal tubule is a nephron tubule that begins at the macula densa and extends to the connecting tubule. http://purl.obolibrary.org/obo/GO_0030054 cell junction http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure A cellular component that forms a specialized region of connection between two or more cells, or between a cell and the extracellular matrix, or between two membrane-bound components of a cell, such as flagella. http://purl.obolibrary.org/obo/GO_0072158 proximal tubule morphogenesis http://purl.obolibrary.org/obo/GO_0072078 nephron tubule morphogenesis The process in which the anatomical structures of a proximal tubule are generated and organized. The proximal tubule is a nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle. It has a brush border epithelial morphology. http://purl.obolibrary.org/obo/GO_0030055 cell-substrate junction http://purl.obolibrary.org/obo/GO_0070161 anchoring junction A cell junction that forms a connection between a cell and the extracellular matrix. http://purl.obolibrary.org/obo/GO_0072160 nephron tubule epithelial cell differentiation http://purl.obolibrary.org/obo/GO_0035850 epithelial cell differentiation involved in kidney development The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the nephron tubule as it progresses from its formation to the mature state. http://purl.obolibrary.org/obo/GO_0030135 coated vesicle http://purl.obolibrary.org/obo/GO_0031410 cytoplasmic vesicle Small membrane-bounded organelle formed by pinching off of a coated region of membrane. Some coats are made of clathrin, whereas others are made from other proteins. http://purl.obolibrary.org/obo/GO_0030148 sphingolipid biosynthetic process http://purl.obolibrary.org/obo/GO_0008610 lipid biosynthetic process The chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid). http://purl.obolibrary.org/obo/GO_0072176 nephric duct development http://purl.obolibrary.org/obo/GO_0072073 kidney epithelium development The process whose specific outcome is the progression of a nephric duct over time, from its initial formation to a mature structure. A nephric duct is a tube that drains a primitive kidney. http://purl.obolibrary.org/obo/GO_0030149 sphingolipid catabolic process http://purl.obolibrary.org/obo/GO_0016042 lipid catabolic process The chemical reactions and pathways resulting in the breakdown of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid). http://purl.obolibrary.org/obo/GO_0072178 nephric duct morphogenesis http://purl.obolibrary.org/obo/GO_0060562 epithelial tube morphogenesis The process in which the anatomical structures of the nephric duct are generated and organized. A nephric duct is a tube that drains a primitive kidney. http://purl.obolibrary.org/obo/GO_0030163 protein catabolic process http://purl.obolibrary.org/obo/GO_0009057 macromolecule catabolic process The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds. http://purl.obolibrary.org/obo/GO_0072189 ureter development http://purl.obolibrary.org/obo/GO_0048513 animal organ development The process whose specific outcome is the progression of the ureter over time, from its formation to the mature structure. The ureter is a muscular tube that transports urine from the kidney to the urinary bladder or from the Malpighian tubule to the hindgut. http://purl.obolibrary.org/obo/GO_0030228 lipoprotein particle receptor activity http://purl.obolibrary.org/obo/GO_0038024 cargo receptor activity Combining with a lipoprotein particle and delivering the lipoprotein particle into the cell via endocytosis. A lipoprotein particle, also known as a lipoprotein, is a clathrate complex consisting of a lipid enwrapped in a protein host without covalent binding in such a way that the complex has a hydrophilic outer surface consisting of all the protein and the polar ends of any phospholipids. http://purl.obolibrary.org/obo/GO_0072197 ureter morphogenesis http://purl.obolibrary.org/obo/GO_0009887 animal organ morphogenesis The process in which the anatomical structures of the ureter are generated and organized. The ureter is a muscular tube that transports urine from the kidney to the urinary bladder. http://purl.obolibrary.org/obo/GO_0030246 carbohydrate binding http://purl.obolibrary.org/obo/GO_0005488 binding Binding to a carbohydrate, which includes monosaccharides, oligosaccharides and polysaccharides as well as substances derived from monosaccharides by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom. Cyclitols are generally not regarded as carbohydrates. http://purl.obolibrary.org/obo/GO_0072497 mesenchymal stem cell differentiation http://purl.obolibrary.org/obo/GO_0048863 stem cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal stem cell. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells. http://purl.obolibrary.org/obo/GO_0030262 apoptotic nuclear changes http://purl.obolibrary.org/obo/GO_0006921 cellular component disassembly involved in execution phase of apoptosis Alterations undergone by nuclei at the molecular and morphological level as part of the execution phase of apoptosis. http://purl.obolibrary.org/obo/GO_0072537 fibroblast activation http://purl.obolibrary.org/obo/GO_0001775 cell activation A change in the morphology or behavior of a fibroblast resulting from exposure to an activating factor such as a cellular or soluble ligand. http://purl.obolibrary.org/obo/GO_0030286 dynein complex http://purl.obolibrary.org/obo/GO_1902494 catalytic complex Any of several large complexes that contain two or three dynein heavy chains and several light chains, and have microtubule motor activity. http://purl.obolibrary.org/obo/GO_0072595 maintenance of protein localization in organelle http://purl.obolibrary.org/obo/GO_0032507 maintenance of protein location in cell Any process in which a protein is maintained in a specific location a specific location on or in an organelle, and is prevented from moving elsewhere. Encompasses establishment of localization in the membrane or lumen of a membrane-bounded organelle. http://purl.obolibrary.org/obo/GO_0030312 external encapsulating structure http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure A structure that lies outside the plasma membrane and surrounds the entire cell or cells. This does not include the periplasmic space. http://purl.obolibrary.org/obo/GO_0072596 establishment of protein localization to chloroplast http://purl.obolibrary.org/obo/GO_0072594 establishment of protein localization to organelle The directed movement of a protein to a specific location in a chloroplast. http://purl.obolibrary.org/obo/GO_0030317 flagellated sperm motility http://purl.obolibrary.org/obo/GO_0060294 cilium movement involved in cell motility The directed, self-propelled movement of a cilium (aka flagellum) that contributes to the movement of a flagellated sperm. http://purl.obolibrary.org/obo/GO_0072657 protein localization to membrane http://purl.obolibrary.org/obo/GO_0051668 localization within membrane A process in which a protein is transported to, or maintained in, a specific location in a membrane. http://purl.obolibrary.org/obo/GO_0030437 ascospore formation http://purl.obolibrary.org/obo/GO_0043935 sexual sporulation resulting in formation of a cellular spore The process in which cells that are products of meiosis acquire the specialized features of ascospores. Ascospores are generally found in clusters of four or eight spores within a single mother cell, the ascus, and are characteristic of the ascomycete fungi (phylum Ascomycota). http://purl.obolibrary.org/obo/GO_0072659 protein localization to plasma membrane http://purl.obolibrary.org/obo/GO_1990778 protein localization to cell periphery A process in which a protein is transported to, or maintained in, a specific location in the plasma membrane. http://purl.obolibrary.org/obo/GO_0030540 female genitalia development http://purl.obolibrary.org/obo/GO_0048806 genitalia development The process whose specific outcome is the progression of the female genitalia over time, from formation to the mature structure. http://purl.obolibrary.org/obo/GO_0072697 protein localization to cell cortex http://purl.obolibrary.org/obo/GO_1990778 protein localization to cell periphery A process in which a protein is transported to, or maintained in, the cell cortex. http://purl.obolibrary.org/obo/GO_0030594 neurotransmitter receptor activity http://purl.obolibrary.org/obo/GO_0038023 signaling receptor activity Combining with a neurotransmitter and transmitting the signal to initiate a change in cell activity. http://purl.obolibrary.org/obo/GO_0072698 protein localization to microtubule cytoskeleton http://purl.obolibrary.org/obo/GO_0044380 protein localization to cytoskeleton A cellular protein localization process in which a protein is transported to, or maintained at, a location within the microtubule cytoskeleton. http://purl.obolibrary.org/obo/GO_0030707 follicle cell of egg chamber development http://purl.obolibrary.org/obo/GO_0003006 developmental process involved in reproduction The process that occurs during oogenesis involving the ovarian follicle cells, somatic cells which surround the germ cells of an ovary. An example of this is found in Drosophila melanogaster. http://purl.obolibrary.org/obo/GO_0030936 transmembrane collagen trimer http://purl.obolibrary.org/obo/GO_0098797 plasma membrane protein complex Any collagen trimer that passes through a lipid bilayer membrane. http://purl.obolibrary.org/obo/GO_0080154 regulation of fertilization http://purl.obolibrary.org/obo/GO_2000241 regulation of reproductive process Any process that modulates the rate, frequency or extent of fertilization. Fertilization is the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy). http://purl.obolibrary.org/obo/GO_0030990 intraciliary transport particle http://purl.obolibrary.org/obo/GO_0032991 protein-containing complex A nonmembrane-bound oligomeric protein complex that participates in bidirectional transport of molecules (cargo) along axonemal microtubules. http://purl.obolibrary.org/obo/GO_0090162 establishment of epithelial cell polarity http://purl.obolibrary.org/obo/GO_0030010 establishment of cell polarity The specification and formation of anisotropic intracellular organization of an epithelial cell. http://purl.obolibrary.org/obo/GO_0031012 extracellular matrix http://purl.obolibrary.org/obo/GO_0030312 external encapsulating structure A structure lying external to one or more cells, which provides structural support, biochemical or biomechanical cues for cells or tissues. http://purl.obolibrary.org/obo/GO_0090168 Golgi reassembly http://purl.obolibrary.org/obo/GO_0022607 cellular component assembly The reformation of the Golgi following its breakdown and partitioning contributing to Golgi inheritance. http://purl.obolibrary.org/obo/GO_0031109 microtubule polymerization or depolymerization http://purl.obolibrary.org/obo/GO_0000226 microtubule cytoskeleton organization Assembly or disassembly of microtubules by the addition or removal of tubulin heterodimers from a microtubule. http://purl.obolibrary.org/obo/GO_0090276 regulation of peptide hormone secretion http://purl.obolibrary.org/obo/GO_0002791 regulation of peptide secretion Any process that modulates the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules. http://purl.obolibrary.org/obo/GO_0031111 negative regulation of microtubule polymerization or depolymerization http://purl.obolibrary.org/obo/GO_0051494 negative regulation of cytoskeleton organization Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule polymerization or depolymerization. http://purl.obolibrary.org/obo/GO_0090316 positive regulation of intracellular protein transport http://purl.obolibrary.org/obo/GO_0051222 positive regulation of protein transport Any process that activates or increases the frequency, rate or extent of the directed movement of proteins within cells. http://purl.obolibrary.org/obo/GO_0031114 regulation of microtubule depolymerization http://purl.obolibrary.org/obo/GO_1901879 regulation of protein depolymerization Any process that modulates the frequency, rate or extent of microtubule depolymerization. http://purl.obolibrary.org/obo/GO_0090317 negative regulation of intracellular protein transport http://purl.obolibrary.org/obo/GO_0051224 negative regulation of protein transport Any process that decreases the frequency, rate or extent of the directed movement of proteins within cells. http://purl.obolibrary.org/obo/GO_0031345 negative regulation of cell projection organization http://purl.obolibrary.org/obo/GO_0051129 negative regulation of cellular component organization Any process that stops, prevents, or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections. http://purl.obolibrary.org/obo/GO_0031406 carboxylic acid binding http://purl.obolibrary.org/obo/GO_0043177 organic acid binding Binding to a carboxylic acid, an organic acid containing one or more carboxyl (COOH) groups or anions (COO-). http://purl.obolibrary.org/obo/GO_0090435 protein localization to nuclear envelope http://purl.obolibrary.org/obo/GO_0034504 protein localization to nucleus A process in which a protein is transported to, or maintained at, a location within a nuclear envelope. http://purl.obolibrary.org/obo/GO_0031965 nuclear membrane http://purl.obolibrary.org/obo/GO_0031090 organelle membrane Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space. http://purl.obolibrary.org/obo/GO_0090497 mesenchymal cell migration http://purl.obolibrary.org/obo/GO_0001667 ameboidal-type cell migration The orderly movement of a mesenchymal cell from one site to another, often during the development of a multicellular organism. http://purl.obolibrary.org/obo/GO_0031966 mitochondrial membrane http://purl.obolibrary.org/obo/GO_0031090 organelle membrane Either of the lipid bilayers that surround the mitochondrion and form the mitochondrial envelope. http://purl.obolibrary.org/obo/GO_0090596 sensory organ morphogenesis http://purl.obolibrary.org/obo/GO_0009887 animal organ morphogenesis Morphogenesis of a sensory organ. A sensory organ is defined as a tissue or set of tissues that work together to receive and transmit signals from external or internal stimuli. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. http://purl.obolibrary.org/obo/GO_0031967 organelle envelope http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure A double membrane structure enclosing an organelle, including two lipid bilayers and the region between them. In some cases, an organelle envelope may have more than two membranes. http://purl.obolibrary.org/obo/GO_0090598 male anatomical structure morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The processes by which anatomical structures that are only present in the male organism are generated and organized. http://purl.obolibrary.org/obo/GO_0031968 organelle outer membrane http://purl.obolibrary.org/obo/GO_0019867 outer membrane The outer, i.e. cytoplasm-facing in a cellular organelle, lipid bilayer of an organelle envelope. http://purl.obolibrary.org/obo/GO_0097237 cellular response to toxic substance http://purl.obolibrary.org/obo/GO_0009636 response to toxic substance Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus. http://purl.obolibrary.org/obo/GO_0031974 membrane-enclosed lumen http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure The enclosed volume within a sealed membrane or between two sealed membranes. Encompasses the volume enclosed by the membranes of a particular organelle, e.g. endoplasmic reticulum lumen, or the space between the two lipid bilayers of a double membrane surrounding an organelle, e.g. nuclear envelope lumen. http://purl.obolibrary.org/obo/GO_0032042 mitochondrial DNA metabolic process http://purl.obolibrary.org/obo/GO_0006259 DNA metabolic process The chemical reactions and pathways involving mitochondrial DNA. http://purl.obolibrary.org/obo/GO_0097355 protein localization to heterochromatin http://purl.obolibrary.org/obo/GO_0071168 protein localization to chromatin Any process in which a protein is transported to, or maintained at, a part of a chromosome that is organized into heterochromatin. http://purl.obolibrary.org/obo/GO_0032350 regulation of hormone metabolic process http://purl.obolibrary.org/obo/GO_0019222 regulation of metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving any hormone. http://purl.obolibrary.org/obo/GO_0032365 intracellular lipid transport http://purl.obolibrary.org/obo/GO_0006869 lipid transport The directed movement of lipids within cells. http://purl.obolibrary.org/obo/GO_0097576 vacuole fusion http://purl.obolibrary.org/obo/GO_0048284 organelle fusion Merging of two or more vacuoles, or of vacuoles and vesicles within a cell to form a single larger vacuole. http://purl.obolibrary.org/obo/GO_0032368 regulation of lipid transport http://purl.obolibrary.org/obo/GO_1905952 regulation of lipid localization Any process that modulates the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0097648 G protein-coupled receptor complex http://purl.obolibrary.org/obo/GO_0098802 plasma membrane signaling receptor complex A protein complex that contains G protein-coupled receptors. http://purl.obolibrary.org/obo/GO_0032507 maintenance of protein location in cell http://purl.obolibrary.org/obo/GO_0045185 maintenance of protein location Any process in which a protein is maintained in a specific location within, or in the membrane of, a cell, and is prevented from moving elsewhere. http://purl.obolibrary.org/obo/GO_0097729 9+2 motile cilium http://purl.obolibrary.org/obo/GO_0031514 motile cilium A motile cilium where the axoneme has a ring of nine outer microtubule doublets plus two central microtubules (and is therefore called a 9+2 axoneme). http://purl.obolibrary.org/obo/GO_0032559 adenyl ribonucleotide binding http://purl.obolibrary.org/obo/GO_0032555 purine ribonucleotide binding Binding to an adenyl ribonucleotide, any compound consisting of adenosine esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety. http://purl.obolibrary.org/obo/GO_0098528 skeletal muscle fiber differentiation http://purl.obolibrary.org/obo/GO_0035914 skeletal muscle cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a skeletal muscle fiber cell. Skeletal muscle fiber differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual skeletal muscle fibers fuse to form bigger myotubes and start to contract. http://purl.obolibrary.org/obo/GO_0032787 monocarboxylic acid metabolic process http://purl.obolibrary.org/obo/GO_0019752 carboxylic acid metabolic process The chemical reactions and pathways involving monocarboxylic acids, any organic acid containing one carboxyl (COOH) group or anion (COO-). http://purl.obolibrary.org/obo/GO_0098751 bone cell development http://purl.obolibrary.org/obo/GO_0048468 cell development The process whose specific outcome is the progression of a bone cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. http://purl.obolibrary.org/obo/GO_0032841 calcitonin binding http://purl.obolibrary.org/obo/GO_0097644 calcitonin family binding Binding to calcitonin, a peptide hormone responsible for reducing serum calcium levels by inhibiting osteoclastic bone reabsorption and promoting renal calcium excretion. It is synthesized and released by the C cells of the thyroid. http://purl.obolibrary.org/obo/GO_0098794 postsynapse http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure The part of a synapse that is part of the post-synaptic cell. http://purl.obolibrary.org/obo/GO_0033036 macromolecule localization http://purl.obolibrary.org/obo/GO_0051179 localization Any process in which a macromolecule is transported to, or maintained in, a specific location. http://purl.obolibrary.org/obo/GO_0098840 protein transport along microtubule http://purl.obolibrary.org/obo/GO_0099118 microtubule-based protein transport The directed movement of a protein along a microtubule, mediated by motor proteins. http://purl.obolibrary.org/obo/GO_0033037 polysaccharide localization http://purl.obolibrary.org/obo/GO_0033036 macromolecule localization Any process in which a polysaccharide is transported to, or maintained in, a specific location. http://purl.obolibrary.org/obo/GO_0099098 microtubule polymerization based movement http://purl.obolibrary.org/obo/GO_0007018 microtubule-based movement The movement of a cellular component as a result of microtubule polymerization. http://purl.obolibrary.org/obo/GO_0033045 regulation of sister chromatid segregation http://purl.obolibrary.org/obo/GO_0051983 regulation of chromosome segregation Any process that modulates the frequency, rate or extent of sister chromatid segregation. http://purl.obolibrary.org/obo/GO_0099632 protein transport within plasma membrane http://purl.obolibrary.org/obo/GO_0032594 protein transport within lipid bilayer A process in which protein is transported from one region of the plasma membrane to another. http://purl.obolibrary.org/obo/GO_0033238 regulation of amine metabolic process http://purl.obolibrary.org/obo/GO_0019222 regulation of metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform amines. http://purl.obolibrary.org/obo/GO_1900116 extracellular negative regulation of signal transduction http://purl.obolibrary.org/obo/GO_1900115 extracellular regulation of signal transduction Any negative regulation of signal transduction that takes place in extracellular region. http://purl.obolibrary.org/obo/GO_0034308 primary alcohol metabolic process http://purl.obolibrary.org/obo/GO_0006066 alcohol metabolic process The chemical reactions and pathways involving primary alcohols. A primary alcohol is any alcohol in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it. http://purl.obolibrary.org/obo/GO_0034309 primary alcohol biosynthetic process http://purl.obolibrary.org/obo/GO_0046165 alcohol biosynthetic process The chemical reactions and pathways resulting in the formation of primary alcohols. A primary alcohol is any alcohol in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it. http://purl.obolibrary.org/obo/GO_1900180 regulation of protein localization to nucleus http://purl.obolibrary.org/obo/GO_0032880 regulation of protein localization Any process that modulates the frequency, rate or extent of protein localization to nucleus. http://purl.obolibrary.org/obo/GO_1900181 negative regulation of protein localization to nucleus http://purl.obolibrary.org/obo/GO_1903828 negative regulation of protein localization Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to nucleus. http://purl.obolibrary.org/obo/GO_0034310 primary alcohol catabolic process http://purl.obolibrary.org/obo/GO_0046164 alcohol catabolic process The chemical reactions and pathways resulting in the breakdown of primary alcohols. A primary alcohol is any alcohol in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it. http://purl.obolibrary.org/obo/GO_1900182 positive regulation of protein localization to nucleus http://purl.obolibrary.org/obo/GO_1903829 positive regulation of protein localization Any process that activates or increases the frequency, rate or extent of protein localization to nucleus. http://purl.obolibrary.org/obo/GO_0034329 cell junction assembly http://purl.obolibrary.org/obo/GO_0034330 cell junction organization A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a cell junction. http://purl.obolibrary.org/obo/GO_1901162 primary amino compound biosynthetic process http://purl.obolibrary.org/obo/GO_0009058 biosynthetic process The chemical reactions and pathways resulting in the formation of primary amino compound. http://purl.obolibrary.org/obo/GO_0034504 protein localization to nucleus http://purl.obolibrary.org/obo/GO_0033365 protein localization to organelle A process in which a protein transports or maintains the localization of another protein to the nucleus. http://purl.obolibrary.org/obo/GO_1901338 catecholamine binding http://purl.obolibrary.org/obo/GO_0005488 binding Binding to catecholamine. http://purl.obolibrary.org/obo/GO_0034655 nucleobase-containing compound catabolic process http://purl.obolibrary.org/obo/GO_0009056 catabolic process The chemical reactions and pathways resulting in the breakdown of nucleobases, nucleosides, nucleotides and nucleic acids. http://purl.obolibrary.org/obo/GO_1901342 regulation of vasculature development http://purl.obolibrary.org/obo/GO_2000026 regulation of multicellular organismal development Any process that modulates the frequency, rate or extent of vasculature development. http://purl.obolibrary.org/obo/GO_0034702 monoatomic ion channel complex http://purl.obolibrary.org/obo/GO_1902495 transmembrane transporter complex A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective monoatomic ion transport down its electrochemical gradient. http://purl.obolibrary.org/obo/GO_1901655 cellular response to ketone http://purl.obolibrary.org/obo/GO_1901701 cellular response to oxygen-containing compound Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ketone stimulus. http://purl.obolibrary.org/obo/GO_0034704 calcium channel complex http://purl.obolibrary.org/obo/GO_0034703 cation channel complex An ion channel complex through which calcium ions pass. http://purl.obolibrary.org/obo/GO_1901699 cellular response to nitrogen compound http://purl.obolibrary.org/obo/GO_1901698 response to nitrogen compound Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen compound stimulus. http://purl.obolibrary.org/obo/GO_0034705 potassium channel complex http://purl.obolibrary.org/obo/GO_0034703 cation channel complex An ion channel complex through which potassium ions pass. http://purl.obolibrary.org/obo/GO_1901701 cellular response to oxygen-containing compound http://purl.obolibrary.org/obo/GO_1901700 response to oxygen-containing compound Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen-containing compound stimulus. http://purl.obolibrary.org/obo/GO_0034765 regulation of monoatomic ion transmembrane transport http://purl.obolibrary.org/obo/GO_0043269 regulation of monoatomic ion transport Any process that modulates the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_1902017 regulation of cilium assembly http://purl.obolibrary.org/obo/GO_0120032 regulation of plasma membrane bounded cell projection assembly Any process that modulates the frequency, rate or extent of cilium assembly. http://purl.obolibrary.org/obo/GO_0034982 mitochondrial protein processing http://purl.obolibrary.org/obo/GO_0016485 protein processing The peptide cleavage of mitochondrial proteins, including cleavage contributing to their import. http://purl.obolibrary.org/obo/GO_1902563 regulation of neutrophil activation http://purl.obolibrary.org/obo/GO_0002694 regulation of leukocyte activation Any process that modulates the frequency, rate or extent of neutrophil activation. http://purl.obolibrary.org/obo/GO_1902564 negative regulation of neutrophil activation http://purl.obolibrary.org/obo/GO_1902563 regulation of neutrophil activation Any process that stops, prevents or reduces the frequency, rate or extent of neutrophil activation. http://purl.obolibrary.org/obo/GO_0035082 axoneme assembly http://purl.obolibrary.org/obo/GO_0022607 cellular component assembly The assembly and organization of an axoneme, the bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements. http://purl.obolibrary.org/obo/GO_1902565 positive regulation of neutrophil activation http://purl.obolibrary.org/obo/GO_1902563 regulation of neutrophil activation Any process that activates or increases the frequency, rate or extent of neutrophil activation. http://purl.obolibrary.org/obo/GO_0035235 ionotropic glutamate receptor signaling pathway http://purl.obolibrary.org/obo/GO_1990806 ligand-gated ion channel signaling pathway The series of molecular signals initiated by glutamate binding to a glutamate receptor on the surface of the target cell, followed by the movement of ions through a channel in the receptor complex, and ending with the regulation of a downstream cellular process, e.g. transcription. http://purl.obolibrary.org/obo/GO_1902566 regulation of eosinophil activation http://purl.obolibrary.org/obo/GO_0002694 regulation of leukocyte activation Any process that modulates the frequency, rate or extent of eosinophil activation. http://purl.obolibrary.org/obo/GO_0035239 tube morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structures of a tube are generated and organized. Epithelial and endothelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system. http://purl.obolibrary.org/obo/GO_1902567 negative regulation of eosinophil activation http://purl.obolibrary.org/obo/GO_1902566 regulation of eosinophil activation Any process that stops, prevents or reduces the frequency, rate or extent of eosinophil activation. http://purl.obolibrary.org/obo/GO_0035240 dopamine binding http://purl.obolibrary.org/obo/GO_0043169 cation binding Binding to dopamine, a catecholamine neurotransmitter formed by aromatic-L-amino-acid decarboxylase from 3,4-dihydroxy-L-phenylalanine. http://purl.obolibrary.org/obo/GO_1902568 positive regulation of eosinophil activation http://purl.obolibrary.org/obo/GO_1902566 regulation of eosinophil activation Any process that activates or increases the frequency, rate or extent of eosinophil activation. http://purl.obolibrary.org/obo/GO_0035265 organ growth http://purl.obolibrary.org/obo/GO_0048589 developmental growth The increase in size or mass of an organ. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that function together as to perform a specific function. http://purl.obolibrary.org/obo/GO_1902913 positive regulation of neuroepithelial cell differentiation http://purl.obolibrary.org/obo/GO_0030858 positive regulation of epithelial cell differentiation Any process that activates or increases the frequency, rate or extent of neuroepithelial cell differentiation. http://purl.obolibrary.org/obo/GO_0035272 exocrine system development http://purl.obolibrary.org/obo/GO_0048731 system development Progression of the exocrine system over time, from its formation to a mature structure. The exocrine system is a system of hormones and glands, where the glands secrete straight to a target site via ducts or tubes. The human exocrine system includes the salivary glands, sweat glands and many glands of the digestive system. http://purl.obolibrary.org/obo/GO_1903119 protein localization to actin cytoskeleton http://purl.obolibrary.org/obo/GO_0044380 protein localization to cytoskeleton A process in which a protein is transported to, or maintained in, the location of an actin cytoskeleton. http://purl.obolibrary.org/obo/GO_0035295 tube development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of a tube over time, from its initial formation to a mature structure. Epithelial and endothelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues including lung and trachea, kidney, the mammary gland, the vascular system and the gastrointestinal and urinary-genital tracts. http://purl.obolibrary.org/obo/GO_1903224 regulation of endodermal cell differentiation http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the frequency, rate or extent of endodermal cell differentiation. http://purl.obolibrary.org/obo/GO_0035381 ATP-gated ion channel activity http://purl.obolibrary.org/obo/GO_0022834 ligand-gated channel activity Enables the transmembrane transfer of an ion by a channel that opens when ATP has been bound by the channel complex or one of its constituent parts. http://purl.obolibrary.org/obo/GO_1903225 negative regulation of endodermal cell differentiation http://purl.obolibrary.org/obo/GO_1903224 regulation of endodermal cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of endodermal cell differentiation. http://purl.obolibrary.org/obo/GO_0035639 purine ribonucleoside triphosphate binding http://purl.obolibrary.org/obo/GO_1901363 heterocyclic compound binding Binding to a purine ribonucleoside triphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with triphosphate on the sugar. http://purl.obolibrary.org/obo/GO_0035725 sodium ion transmembrane transport http://purl.obolibrary.org/obo/GO_0098655 monoatomic cation transmembrane transport A process in which a sodium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_1903306 negative regulation of regulated secretory pathway http://purl.obolibrary.org/obo/GO_1903305 regulation of regulated secretory pathway Any process that stops, prevents or reduces the frequency, rate or extent of regulated secretory pathway. http://purl.obolibrary.org/obo/GO_0036064 ciliary basal body http://purl.obolibrary.org/obo/GO_0005815 microtubule organizing center A membrane-tethered, short cylindrical array of microtubules and associated proteins found at the base of a eukaryotic cilium (also called flagellum) that is similar in structure to a centriole and derives from it. The cilium basal body is the site of assembly and remodeling of the cilium and serves as a nucleation site for axoneme growth. As well as anchoring the cilium, it is thought to provide a selective gateway regulating the entry of ciliary proteins and vesicles by intraflagellar transport. http://purl.obolibrary.org/obo/GO_1903307 positive regulation of regulated secretory pathway http://purl.obolibrary.org/obo/GO_1903305 regulation of regulated secretory pathway Any process that activates or increases the frequency, rate or extent of regulated secretory pathway. http://purl.obolibrary.org/obo/GO_0036379 myofilament http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure Any of the smallest contractile units of a myofibril (striated muscle fiber). http://purl.obolibrary.org/obo/GO_1903706 regulation of hemopoiesis http://purl.obolibrary.org/obo/GO_0060284 regulation of cell development Any process that modulates the frequency, rate or extent of hemopoiesis. http://purl.obolibrary.org/obo/GO_0038024 cargo receptor activity http://purl.obolibrary.org/obo/GO_0003674 molecular_function Binding specifically to a substance (cargo) to deliver it to a transport vesicle. Cargo receptors span membranes (for instance the plasma membrane or the endoplasmic reticulum membrane), binding simultaneously to cargo molecules and coat adaptors, to efficiently recruit the cargo molecules to nascent vesicles. http://purl.obolibrary.org/obo/GO_1903707 negative regulation of hemopoiesis http://purl.obolibrary.org/obo/GO_0010721 negative regulation of cell development Any process that stops, prevents or reduces the frequency, rate or extent of hemopoiesis. http://purl.obolibrary.org/obo/GO_0038161 prolactin signaling pathway http://purl.obolibrary.org/obo/GO_0019221 cytokine-mediated signaling pathway The series of molecular signals initiated by the binding of the peptide hormone prolactin to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. http://purl.obolibrary.org/obo/GO_1903708 positive regulation of hemopoiesis http://purl.obolibrary.org/obo/GO_0010720 positive regulation of cell development Any process that activates or increases the frequency, rate or extent of hemopoiesis. http://purl.obolibrary.org/obo/GO_0038170 somatostatin signaling pathway http://purl.obolibrary.org/obo/GO_0038169 somatostatin receptor signaling pathway A G protein-coupled receptor signaling pathway initiated by somatostatin binding to a somatostatin receptor (SSTR), and ending with the regulation of a downstream cellular process, e.g. transcription. http://purl.obolibrary.org/obo/GO_1903729 regulation of plasma membrane organization http://purl.obolibrary.org/obo/GO_0051128 regulation of cellular component organization Any process that modulates the frequency, rate or extent of plasma membrane organization. http://purl.obolibrary.org/obo/GO_0038188 cholecystokinin signaling pathway http://purl.obolibrary.org/obo/GO_0007186 G protein-coupled receptor signaling pathway A G protein-coupled receptor signaling pathway initiated by cholecystokinin binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. http://purl.obolibrary.org/obo/GO_1903778 protein localization to vacuolar membrane http://purl.obolibrary.org/obo/GO_0072665 protein localization to vacuole A process in which a protein is transported to, or maintained in, a location within a vacuolar membrane. http://purl.obolibrary.org/obo/GO_0040029 epigenetic regulation of gene expression http://purl.obolibrary.org/obo/GO_0010468 regulation of gene expression A process that modulates the frequency, rate or extent of gene expression through chromatin remodeling either by modifying higher order chromatin fiber structure, nucleosomal histones, or cytosine methylation of DNA. Once established, this regulation may be maintained over many cell divisions. It can also be heritable in the absence of the instigating signal. http://purl.obolibrary.org/obo/GO_1904018 positive regulation of vasculature development http://purl.obolibrary.org/obo/GO_1901342 regulation of vasculature development Any process that activates or increases the frequency, rate or extent of vasculature development. http://purl.obolibrary.org/obo/GO_0042044 fluid transport http://purl.obolibrary.org/obo/GO_0006810 transport The directed movement of substances that are in liquid form in normal living conditions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_1904063 negative regulation of cation transmembrane transport http://purl.obolibrary.org/obo/GO_1904062 regulation of monoatomic cation transmembrane transport Any process that stops, prevents or reduces the frequency, rate or extent of cation transmembrane transport. http://purl.obolibrary.org/obo/GO_0042158 lipoprotein biosynthetic process http://purl.obolibrary.org/obo/GO_0042157 lipoprotein metabolic process The chemical reactions and pathways resulting in the formation of any conjugated, water-soluble protein in which the covalently attached nonprotein group consists of a lipid or lipids. http://purl.obolibrary.org/obo/GO_1904064 positive regulation of cation transmembrane transport http://purl.obolibrary.org/obo/GO_1904062 regulation of monoatomic cation transmembrane transport Any process that activates or increases the frequency, rate or extent of cation transmembrane transport. http://purl.obolibrary.org/obo/GO_0042175 nuclear outer membrane-endoplasmic reticulum membrane network http://purl.obolibrary.org/obo/GO_0016020 membrane The continuous network of membranes encompassing the nuclear outer membrane and the endoplasmic reticulum membrane. http://purl.obolibrary.org/obo/GO_1905156 negative regulation of photosynthesis http://purl.obolibrary.org/obo/GO_0010109 regulation of photosynthesis Any process that stops, prevents or reduces the frequency, rate or extent of photosynthesis. http://purl.obolibrary.org/obo/GO_0042180 ketone metabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process The chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms, as carried out by individual cells. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups. http://purl.obolibrary.org/obo/GO_0042181 ketone biosynthetic process http://purl.obolibrary.org/obo/GO_0044283 small molecule biosynthetic process The chemical reactions and pathways resulting in the formation of ketones, a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups. http://purl.obolibrary.org/obo/GO_1905515 non-motile cilium assembly http://purl.obolibrary.org/obo/GO_0060271 cilium assembly The aggregation, arrangement and bonding together of a set of components to form a non-motile cilium. http://purl.obolibrary.org/obo/GO_0042182 ketone catabolic process http://purl.obolibrary.org/obo/GO_0044282 small molecule catabolic process The chemical reactions and pathways resulting in the breakdown of ketones, a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups. http://purl.obolibrary.org/obo/GO_0042219 modified amino acid catabolic process http://purl.obolibrary.org/obo/GO_0009056 catabolic process The chemical reactions and pathways resulting in the breakdown of compounds derived from amino acids, organic acids containing one or more amino substituents. http://purl.obolibrary.org/obo/GO_1905690 nucleus disassembly http://purl.obolibrary.org/obo/GO_1903008 organelle disassembly The disaggregation of a nucleus into its constituent components. http://purl.obolibrary.org/obo/GO_0042303 molting cycle http://purl.obolibrary.org/obo/GO_0032501 multicellular organismal process The periodic casting off and regeneration of an outer covering of cuticle, feathers, hair, horns, skin, etc. http://purl.obolibrary.org/obo/GO_1905770 regulation of mesodermal cell differentiation http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the frequency, rate or extent of mesodermal cell differentiation. http://purl.obolibrary.org/obo/GO_0042379 chemokine receptor binding http://purl.obolibrary.org/obo/GO_0005126 cytokine receptor binding Binding to a chemokine receptor. http://purl.obolibrary.org/obo/GO_0042386 hemocyte differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires the characteristics of a mature hemocyte. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. http://purl.obolibrary.org/obo/GO_0042398 modified amino acid biosynthetic process http://purl.obolibrary.org/obo/GO_0009058 biosynthetic process The chemical reactions and pathways resulting in the formation of compounds derived from amino acids, organic acids containing one or more amino substituents. http://purl.obolibrary.org/obo/GO_1905771 negative regulation of mesodermal cell differentiation http://purl.obolibrary.org/obo/GO_1905770 regulation of mesodermal cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of mesodermal cell differentiation. http://purl.obolibrary.org/obo/GO_0042403 thyroid hormone metabolic process http://purl.obolibrary.org/obo/GO_0042445 hormone metabolic process The chemical reactions and pathways involving any of the compounds secreted by the thyroid gland, largely thyroxine and triiodothyronine. http://purl.obolibrary.org/obo/GO_1990777 lipoprotein particle http://purl.obolibrary.org/obo/GO_0032994 protein-lipid complex A spherical particle containing non-covalently associated proteins and lipids. Examples are plasma lipoprotein particles which transport lipids in the blood or lymph. http://purl.obolibrary.org/obo/GO_1990778 protein localization to cell periphery http://purl.obolibrary.org/obo/GO_0008104 intracellular protein localization A process in which a protein is transported to, or maintained in, the cell periphery. http://purl.obolibrary.org/obo/GO_0042416 dopamine biosynthetic process http://purl.obolibrary.org/obo/GO_0042423 catecholamine biosynthetic process The chemical reactions and pathways resulting in the formation of dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline. http://purl.obolibrary.org/obo/GO_2000355 negative regulation of ovarian follicle development http://purl.obolibrary.org/obo/GO_2000354 regulation of ovarian follicle development Any process that stops, prevents or reduces the frequency, rate or extent of ovarian follicle development. http://purl.obolibrary.org/obo/GO_2000383 regulation of ectoderm development http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of ectoderm development. http://purl.obolibrary.org/obo/GO_0042427 serotonin biosynthetic process http://purl.obolibrary.org/obo/GO_0042435 indole-containing compound biosynthetic process The chemical reactions and pathways resulting in the formation of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties. http://purl.obolibrary.org/obo/GO_2000384 negative regulation of ectoderm development http://purl.obolibrary.org/obo/GO_2000383 regulation of ectoderm development Any process that stops, prevents or reduces the frequency, rate or extent of ectoderm development. http://purl.obolibrary.org/obo/GO_2000387 regulation of antral ovarian follicle growth http://purl.obolibrary.org/obo/GO_2000241 regulation of reproductive process Any process that modulates the frequency, rate or extent of antral ovarian follicle growth. http://purl.obolibrary.org/obo/GO_0042430 indole-containing compound metabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process The chemical reactions and pathways involving compounds that contain an indole (2,3-benzopyrrole) skeleton. http://purl.obolibrary.org/obo/GO_2000388 positive regulation of antral ovarian follicle growth http://purl.obolibrary.org/obo/GO_2000243 positive regulation of reproductive process Any process that activates or increases the frequency, rate or extent of antral ovarian follicle growth. http://purl.obolibrary.org/obo/GO_0042440 pigment metabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process The chemical reactions and pathways involving pigment, any general or particular coloring matter in living organisms, e.g. melanin. http://purl.obolibrary.org/obo/GO_2000514 regulation of CD4-positive, alpha-beta T cell activation http://purl.obolibrary.org/obo/GO_0046634 regulation of alpha-beta T cell activation Any process that modulates the frequency, rate or extent of CD4-positive, alpha-beta T cell activation. http://purl.obolibrary.org/obo/GO_0042446 hormone biosynthetic process http://purl.obolibrary.org/obo/GO_0042445 hormone metabolic process The chemical reactions and pathways resulting in the formation of any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone. http://purl.obolibrary.org/obo/GO_2000515 negative regulation of CD4-positive, alpha-beta T cell activation http://purl.obolibrary.org/obo/GO_2000514 regulation of CD4-positive, alpha-beta T cell activation Any process that stops, prevents or reduces the frequency, rate or extent of CD4-positive, alpha-beta T cell activation. http://purl.obolibrary.org/obo/GO_0042447 hormone catabolic process http://purl.obolibrary.org/obo/GO_0042445 hormone metabolic process The chemical reactions and pathways resulting in the breakdown of any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone. http://purl.obolibrary.org/obo/GO_0042448 progesterone metabolic process http://purl.obolibrary.org/obo/GO_0042180 ketone metabolic process The chemical reactions and pathways involving progesterone, a steroid hormone produced in the ovary which prepares and maintains the uterus for pregnancy. Also found in plants. http://purl.obolibrary.org/obo/GO_0042461 photoreceptor cell development http://purl.obolibrary.org/obo/GO_0048666 neuron development Development of a photoreceptor, a cell that responds to incident electromagnetic radiation, particularly visible light. http://purl.obolibrary.org/obo/GO_2000516 positive regulation of CD4-positive, alpha-beta T cell activation http://purl.obolibrary.org/obo/GO_2000514 regulation of CD4-positive, alpha-beta T cell activation Any process that activates or increases the frequency, rate or extent of CD4-positive, alpha-beta T cell activation. http://purl.obolibrary.org/obo/GO_0042562 hormone binding http://purl.obolibrary.org/obo/GO_0005488 binding Binding to an hormone, a naturally occurring substance secreted by specialized cells that affect the metabolism or behavior of cells possessing functional receptors for the hormone. Hormones may be produced by the same, or different, cell as express the receptor. http://purl.obolibrary.org/obo/GO_2000542 negative regulation of gastrulation http://purl.obolibrary.org/obo/GO_0010470 regulation of gastrulation Any process that stops, prevents or reduces the frequency, rate or extent of gastrulation. http://purl.obolibrary.org/obo/GO_0043005 neuron projection http://purl.obolibrary.org/obo/GO_0120025 plasma membrane bounded cell projection A prolongation or process extending from a nerve cell, e.g. an axon or dendrite. http://purl.obolibrary.org/obo/GO_0043021 ribonucleoprotein complex binding http://purl.obolibrary.org/obo/GO_0044877 protein-containing complex binding Binding to a complex of RNA and protein. http://purl.obolibrary.org/obo/GO_0043039 tRNA aminoacylation http://purl.obolibrary.org/obo/GO_0043038 amino acid activation The chemical reactions and pathways by which the various amino acids become bonded to their corresponding tRNAs. The most common route for synthesis of aminoacyl tRNA is by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA and the alpha carboxylic acid group of an amino acid, usually catalyzed by the cognate aminoacyl-tRNA ligase. A given aminoacyl-tRNA ligase aminoacylates all species of an isoaccepting group of tRNA molecules. http://purl.obolibrary.org/obo/GO_2000881 regulation of starch catabolic process http://purl.obolibrary.org/obo/GO_2000904 regulation of starch metabolic process Any process that modulates the frequency, rate or extent of starch catabolic process. http://purl.obolibrary.org/obo/GO_0043066 negative regulation of apoptotic process http://purl.obolibrary.org/obo/GO_0043069 negative regulation of programmed cell death Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process. http://purl.obolibrary.org/obo/GO_2000883 positive regulation of starch catabolic process http://purl.obolibrary.org/obo/GO_0045913 positive regulation of carbohydrate metabolic process Any process that activates or increases the frequency, rate or extent of starch catabolic process. http://purl.obolibrary.org/obo/GO_0043085 positive regulation of catalytic activity http://purl.obolibrary.org/obo/GO_0050790 regulation of catalytic activity Any process that activates or increases the activity of an enzyme. http://purl.obolibrary.org/obo/GO_0043086 negative regulation of catalytic activity http://purl.obolibrary.org/obo/GO_0050790 regulation of catalytic activity Any process that stops or reduces the activity of an enzyme. http://purl.obolibrary.org/obo/GO_2000980 regulation of inner ear receptor cell differentiation http://purl.obolibrary.org/obo/GO_0045631 regulation of mechanoreceptor differentiation Any process that modulates the frequency, rate or extent of inner ear receptor cell differentiation. http://purl.obolibrary.org/obo/GO_0043170 macromolecule metabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. http://purl.obolibrary.org/obo/GO_0043176 amine binding http://purl.obolibrary.org/obo/GO_0005488 binding Binding to an amine, a weakly basic organic compound that contains an amino or a substituted amino group. http://purl.obolibrary.org/obo/GO_2000981 negative regulation of inner ear receptor cell differentiation http://purl.obolibrary.org/obo/GO_2000980 regulation of inner ear receptor cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of inner ear receptor cell differentiation. http://purl.obolibrary.org/obo/GO_0043231 intracellular membrane-bounded organelle http://purl.obolibrary.org/obo/GO_0043229 intracellular organelle Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane. http://purl.obolibrary.org/obo/GO_2000982 positive regulation of inner ear receptor cell differentiation http://purl.obolibrary.org/obo/GO_2000980 regulation of inner ear receptor cell differentiation Any process that activates or increases the frequency, rate or extent of inner ear receptor cell differentiation. http://purl.obolibrary.org/obo/GO_0043244 regulation of protein-containing complex disassembly http://purl.obolibrary.org/obo/GO_0051128 regulation of cellular component organization Any process that modulates the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components. http://purl.obolibrary.org/obo/GO_2001028 positive regulation of endothelial cell chemotaxis http://purl.obolibrary.org/obo/GO_0010595 positive regulation of endothelial cell migration Any process that activates or increases the frequency, rate or extent of endothelial cell chemotaxis. http://purl.obolibrary.org/obo/GO_0043255 regulation of carbohydrate biosynthetic process http://purl.obolibrary.org/obo/GO_0009889 regulation of biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of carbohydrates. http://purl.obolibrary.org/obo/GO_2001057 reactive nitrogen species metabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process The chemical reactions and pathways involving a reactive nitrogen species. http://purl.obolibrary.org/obo/GO_0043292 contractile muscle fiber http://purl.obolibrary.org/obo/GO_0099512 supramolecular fiber Fibers, composed of actin, myosin, and associated proteins, found in cells of smooth or striated muscle. http://purl.obolibrary.org/obo/GO_2001185 regulation of CD8-positive, alpha-beta T cell activation http://purl.obolibrary.org/obo/GO_0046634 regulation of alpha-beta T cell activation Any process that modulates the frequency, rate or extent of CD8-positive, alpha-beta T cell activation. http://purl.obolibrary.org/obo/GO_0043296 apical junction complex http://purl.obolibrary.org/obo/GO_0005911 cell-cell junction A functional unit located near the cell apex at the points of contact between epithelial cells, which in vertebrates is composed of the tight junction, the zonula adherens, and desmosomes and in some invertebrates, such as Drosophila, is composed of the subapical complex (SAC), the zonula adherens and the septate junction. Functions in the regulation of cell polarity, tissue integrity and intercellular adhesion and permeability. http://purl.obolibrary.org/obo/GO_2001186 negative regulation of CD8-positive, alpha-beta T cell activation http://purl.obolibrary.org/obo/GO_2001185 regulation of CD8-positive, alpha-beta T cell activation Any process that stops, prevents or reduces the frequency, rate or extent of CD8-positive, alpha-beta T cell activation. http://purl.obolibrary.org/obo/GO_0043470 regulation of carbohydrate catabolic process http://purl.obolibrary.org/obo/GO_0009894 regulation of catabolic process Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of carbohydrates. http://purl.obolibrary.org/obo/GO_2001187 positive regulation of CD8-positive, alpha-beta T cell activation http://purl.obolibrary.org/obo/GO_2001185 regulation of CD8-positive, alpha-beta T cell activation Any process that activates or increases the frequency, rate or extent of CD8-positive, alpha-beta T cell activation. http://purl.obolibrary.org/obo/GO_0043559 insulin binding http://purl.obolibrary.org/obo/GO_0017046 peptide hormone binding Binding to insulin, a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms. http://purl.obolibrary.org/obo/GO_0080164 regulation of nitric oxide metabolic process http://purl.obolibrary.org/obo/GO_0019222 regulation of metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water. http://purl.obolibrary.org/obo/GO_0043648 dicarboxylic acid metabolic process http://purl.obolibrary.org/obo/GO_0019752 carboxylic acid metabolic process The chemical reactions and pathways involving dicarboxylic acids, any organic acid containing two carboxyl (COOH) groups or anions (COO-). http://purl.obolibrary.org/obo/GO_0086001 cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_0001508 action potential An action potential that occurs in a cardiac muscle cell. http://purl.obolibrary.org/obo/GO_0043649 dicarboxylic acid catabolic process http://purl.obolibrary.org/obo/GO_0046395 carboxylic acid catabolic process The chemical reactions and pathways resulting in the breakdown of dicarboxylic acids, any organic acid containing two carboxyl (-COOH) groups. http://purl.obolibrary.org/obo/GO_0086002 cardiac muscle cell action potential involved in contraction http://purl.obolibrary.org/obo/GO_0086001 cardiac muscle cell action potential An action potential that occurs in a cardiac muscle cell and is involved in its contraction. http://purl.obolibrary.org/obo/GO_0043650 dicarboxylic acid biosynthetic process http://purl.obolibrary.org/obo/GO_0046394 carboxylic acid biosynthetic process The chemical reactions and pathways resulting in the formation of dicarboxylic acids, any organic acid containing two carboxyl (-COOH) groups. http://purl.obolibrary.org/obo/GO_0086003 cardiac muscle cell contraction http://purl.obolibrary.org/obo/GO_0070252 actin-mediated cell contraction The actin filament-based process in which cytoplasmic actin filaments slide past one another resulting in contraction of a cardiac muscle cell. http://purl.obolibrary.org/obo/GO_0044042 glucan metabolic process http://purl.obolibrary.org/obo/GO_0005976 polysaccharide metabolic process The chemical reactions and pathways involving glucans, polysaccharides consisting only of glucose residues. http://purl.obolibrary.org/obo/GO_0086004 regulation of cardiac muscle cell contraction http://purl.obolibrary.org/obo/GO_0055117 regulation of cardiac muscle contraction Any process that modulates the frequency, rate or extent of cardiac muscle cell contraction. http://purl.obolibrary.org/obo/GO_0044060 regulation of endocrine process http://purl.obolibrary.org/obo/GO_0044057 regulation of system process Any process that modulates the frequency, rate or extent of an endocrine process, a process involving the secretion of or response to endocrine hormones. An endocrine hormone is a hormone released into the circulatory system. http://purl.obolibrary.org/obo/GO_0086005 ventricular cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_0086002 cardiac muscle cell action potential involved in contraction An action potential that occurs in a ventricular cardiac muscle cell. http://purl.obolibrary.org/obo/GO_0044087 regulation of cellular component biogenesis http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of cellular component biogenesis, a process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component. http://purl.obolibrary.org/obo/GO_0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_0005248 voltage-gated sodium channel activity Enables the transmembrane transfer of a sodium ion by a voltage-gated channel through the plasma membrane of a cardiac muscle cell contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. http://purl.obolibrary.org/obo/GO_0044238 primary metabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism. http://purl.obolibrary.org/obo/GO_0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_0005245 voltage-gated calcium channel activity Enables the transmembrane transfer of a calcium ion by a voltage-gated channel across the plasma membrane of a cardiac muscle cell that contributes to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. http://purl.obolibrary.org/obo/GO_0044281 small molecule metabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process The chemical reactions and pathways involving small molecules, any low molecular weight, monomeric, non-encoded molecule. http://purl.obolibrary.org/obo/GO_0044706 multi-multicellular organism process http://purl.obolibrary.org/obo/GO_0032501 multicellular organismal process A multicellular organism process which involves another multicellular organism of the same or different species. http://purl.obolibrary.org/obo/GO_0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization http://purl.obolibrary.org/obo/GO_0005249 voltage-gated potassium channel activity Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of a cardiac muscle cell contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. http://purl.obolibrary.org/obo/GO_0045111 intermediate filament cytoskeleton http://purl.obolibrary.org/obo/GO_0005856 cytoskeleton Cytoskeletal structure made from intermediate filaments, typically organized in the cytosol as an extended system that stretches from the nuclear envelope to the plasma membrane. Some intermediate filaments run parallel to the cell surface, while others traverse the cytosol; together they form an internal framework that helps support the shape and resilience of the cell. http://purl.obolibrary.org/obo/GO_0045132 meiotic chromosome segregation http://purl.obolibrary.org/obo/GO_1903046 meiotic cell cycle process The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets during M phase of the meiotic cell cycle. http://purl.obolibrary.org/obo/GO_0045214 sarcomere organization http://purl.obolibrary.org/obo/GO_0031032 actomyosin structure organization The myofibril assembly process that results in the organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs. http://purl.obolibrary.org/obo/GO_0086010 membrane depolarization during action potential http://purl.obolibrary.org/obo/GO_0051899 membrane depolarization The process in which membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential. http://purl.obolibrary.org/obo/GO_0045236 CXCR chemokine receptor binding http://purl.obolibrary.org/obo/GO_0042379 chemokine receptor binding Binding to a chemokine receptor in the CXCR family. http://purl.obolibrary.org/obo/GO_0086011 membrane repolarization during action potential http://purl.obolibrary.org/obo/GO_0086009 membrane repolarization The process in which ions are transported across a membrane such that the membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential. http://purl.obolibrary.org/obo/GO_0045443 juvenile hormone secretion http://purl.obolibrary.org/obo/GO_0140353 lipid export from cell The regulated release of juvenile hormones, the three sesquiterpenoid derivatives that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis. http://purl.obolibrary.org/obo/GO_0086012 membrane depolarization during cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_0086010 membrane depolarization during action potential The process in which cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential. http://purl.obolibrary.org/obo/GO_0045455 ecdysteroid metabolic process http://purl.obolibrary.org/obo/GO_0042445 hormone metabolic process The chemical reactions and pathways involving ecdysteroids, a group of polyhydroxylated ketosteroids ubiquitous in insects and other arthropods, in which they initiate post-embryonic development, including the metamorphosis of immature forms and the development of the reproductive system and the maturation of oocytes in adult females. http://purl.obolibrary.org/obo/GO_0086013 membrane repolarization during cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_0099622 cardiac muscle cell membrane repolarization The process in which ions are transported across a membrane such that the cardiac muscle cell plasma membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential. http://purl.obolibrary.org/obo/GO_0045456 ecdysteroid biosynthetic process http://purl.obolibrary.org/obo/GO_0045455 ecdysteroid metabolic process The chemical reactions and pathways resulting in the formation of ecdysteroids, a group of polyhydroxylated ketosteroids which initiate post-embryonic development. http://purl.obolibrary.org/obo/GO_0086014 atrial cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_0086002 cardiac muscle cell action potential involved in contraction An action potential that occurs in an atrial cardiac muscle cell. http://purl.obolibrary.org/obo/GO_0045457 ecdysteroid secretion http://purl.obolibrary.org/obo/GO_0035929 steroid hormone secretion The regulated release of ecdysteroids, a group of polyhydroxylated ketosteroids which initiate post-embryonic development. http://purl.obolibrary.org/obo/GO_0086015 SA node cell action potential http://purl.obolibrary.org/obo/GO_0086001 cardiac muscle cell action potential An action potential that occurs in a sinoatrial node cardiac muscle cell. http://purl.obolibrary.org/obo/GO_0045465 R8 cell differentiation http://purl.obolibrary.org/obo/GO_0001751 compound eye photoreceptor cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of the R8 photoreceptor. http://purl.obolibrary.org/obo/GO_0086016 AV node cell action potential http://purl.obolibrary.org/obo/GO_0086001 cardiac muscle cell action potential An action potential that occurs in an atrioventricular node cardiac muscle cell. http://purl.obolibrary.org/obo/GO_0045466 R7 cell differentiation http://purl.obolibrary.org/obo/GO_0001751 compound eye photoreceptor cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of the R7 photoreceptor. http://purl.obolibrary.org/obo/GO_0045596 negative regulation of cell differentiation http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of cell differentiation. http://purl.obolibrary.org/obo/GO_0086017 Purkinje myocyte action potential http://purl.obolibrary.org/obo/GO_0086001 cardiac muscle cell action potential An action potential that occurs in a Purkinje myocyte. http://purl.obolibrary.org/obo/GO_0086018 SA node cell to atrial cardiac muscle cell signaling http://purl.obolibrary.org/obo/GO_0086070 SA node cell to atrial cardiac muscle cell communication Any process that mediates the transfer of information from an SA node cardiomyocyte to an atrial cardiomyocyte. http://purl.obolibrary.org/obo/GO_0045814 negative regulation of gene expression, epigenetic http://purl.obolibrary.org/obo/GO_0040029 epigenetic regulation of gene expression An epigenetic process that silences gene expression at specific genomic regions through chromatin remodeling either by modifying higher order chromatin fiber structure, nucleosomal histones, or the cytosine DNA methylation. http://purl.obolibrary.org/obo/GO_0086026 atrial cardiac muscle cell to AV node cell signaling http://purl.obolibrary.org/obo/GO_0086066 atrial cardiac muscle cell to AV node cell communication Any process that mediates the transfer of information from an atrial cardiomyocyte to an AV node cell. http://purl.obolibrary.org/obo/GO_0045930 negative regulation of mitotic cell cycle http://purl.obolibrary.org/obo/GO_0045786 negative regulation of cell cycle Any process that stops, prevents or reduces the rate or extent of progression through the mitotic cell cycle. http://purl.obolibrary.org/obo/GO_0086027 AV node cell to bundle of His cell signaling http://purl.obolibrary.org/obo/GO_0086067 AV node cell to bundle of His cell communication Any process that mediates the transfer of information from an AV node cardiac muscle cell to a bundle of His cardiomyocyte. http://purl.obolibrary.org/obo/GO_0046031 ADP metabolic process http://purl.obolibrary.org/obo/GO_0009179 purine ribonucleoside diphosphate metabolic process The chemical reactions and pathways involving ADP, adenosine 5'-diphosphate. http://purl.obolibrary.org/obo/GO_0046034 ATP metabolic process http://purl.obolibrary.org/obo/GO_0009205 purine ribonucleoside triphosphate metabolic process The chemical reactions and pathways involving ATP, adenosine triphosphate, a universally important coenzyme and enzyme regulator. http://purl.obolibrary.org/obo/GO_0086028 bundle of His cell to Purkinje myocyte signaling http://purl.obolibrary.org/obo/GO_0086069 bundle of His cell to Purkinje myocyte communication Any process that mediates the transfer of information from a bundle of His cardiomyocyte to a Purkinje myocyte. http://purl.obolibrary.org/obo/GO_0086029 Purkinje myocyte to ventricular cardiac muscle cell signaling http://purl.obolibrary.org/obo/GO_0086068 Purkinje myocyte to ventricular cardiac muscle cell communication Any process that mediates the transfer of information from a Purkinje myocyte to a ventricular cardiac muscle cell. http://purl.obolibrary.org/obo/GO_0046148 pigment biosynthetic process http://purl.obolibrary.org/obo/GO_0042440 pigment metabolic process The chemical reactions and pathways resulting in the formation of a pigment, any general or particular coloring matter in living organisms, e.g. melanin. http://purl.obolibrary.org/obo/GO_0086041 voltage-gated potassium channel activity involved in SA node cell action potential depolarization http://purl.obolibrary.org/obo/GO_0005249 voltage-gated potassium channel activity Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of an SA node cardiac muscle cell contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. http://purl.obolibrary.org/obo/GO_0086043 bundle of His cell action potential http://purl.obolibrary.org/obo/GO_0086001 cardiac muscle cell action potential An action potential that occurs in a bundle of His cell. http://purl.obolibrary.org/obo/GO_0046164 alcohol catabolic process http://purl.obolibrary.org/obo/GO_0044282 small molecule catabolic process The chemical reactions and pathways resulting in the breakdown of alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom. http://purl.obolibrary.org/obo/GO_0086045 membrane depolarization during AV node cell action potential http://purl.obolibrary.org/obo/GO_0086012 membrane depolarization during cardiac muscle cell action potential The process in which AV node cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential. http://purl.obolibrary.org/obo/GO_0046184 aldehyde biosynthetic process http://purl.obolibrary.org/obo/GO_0009058 biosynthetic process The chemical reactions and pathways resulting in the formation of aldehydes, any organic compound with the formula R-CH=O. http://purl.obolibrary.org/obo/GO_0086046 membrane depolarization during SA node cell action potential http://purl.obolibrary.org/obo/GO_0086012 membrane depolarization during cardiac muscle cell action potential The process in which SA node cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential. http://purl.obolibrary.org/obo/GO_0046189 phenol-containing compound biosynthetic process http://purl.obolibrary.org/obo/GO_0009058 biosynthetic process The chemical reactions and pathways resulting in the formation of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring. http://purl.obolibrary.org/obo/GO_0086047 membrane depolarization during Purkinje myocyte cell action potential http://purl.obolibrary.org/obo/GO_0086012 membrane depolarization during cardiac muscle cell action potential The process in which Purkinje myocyte membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential. http://purl.obolibrary.org/obo/GO_0046209 nitric oxide metabolic process http://purl.obolibrary.org/obo/GO_2001057 reactive nitrogen species metabolic process The chemical reactions and pathways involving nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water. http://purl.obolibrary.org/obo/GO_0086048 membrane depolarization during bundle of His cell action potential http://purl.obolibrary.org/obo/GO_0086012 membrane depolarization during cardiac muscle cell action potential The process in which bundle of His cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential. http://purl.obolibrary.org/obo/GO_0046344 ecdysteroid catabolic process http://purl.obolibrary.org/obo/GO_0045455 ecdysteroid metabolic process The chemical reactions and pathways resulting in the breakdown of ecdysteroids, a group of polyhydroxylated ketosteroids which initiate post-embryonic development. http://purl.obolibrary.org/obo/GO_0086049 membrane repolarization during AV node cell action potential http://purl.obolibrary.org/obo/GO_0086013 membrane repolarization during cardiac muscle cell action potential The process in which ions are transported across a membrane such that the AV node cardiac muscle cell membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential. http://purl.obolibrary.org/obo/GO_0046365 monosaccharide catabolic process http://purl.obolibrary.org/obo/GO_0044282 small molecule catabolic process The chemical reactions and pathways resulting in the breakdown of monosaccharides, polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. http://purl.obolibrary.org/obo/GO_0086050 membrane repolarization during bundle of His cell action potential http://purl.obolibrary.org/obo/GO_0086013 membrane repolarization during cardiac muscle cell action potential The process in which ions are transported across a membrane such that the bundle of His cardiac muscle cell membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential. http://purl.obolibrary.org/obo/GO_0046390 ribose phosphate biosynthetic process http://purl.obolibrary.org/obo/GO_1901137 carbohydrate derivative biosynthetic process The chemical reactions and pathways resulting in the formation of ribose phosphate, any phosphorylated ribose sugar. http://purl.obolibrary.org/obo/GO_0086051 membrane repolarization during Purkinje myocyte action potential http://purl.obolibrary.org/obo/GO_0086013 membrane repolarization during cardiac muscle cell action potential The process in which ions are transported across a membrane such that the Purkinje myocyte membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential. http://purl.obolibrary.org/obo/GO_0046479 glycosphingolipid catabolic process http://purl.obolibrary.org/obo/GO_0019377 glycolipid catabolic process The chemical reactions and pathways resulting in the breakdown of glycosphingolipid, a compound with residues of sphingoid and at least one monosaccharide. http://purl.obolibrary.org/obo/GO_0086052 membrane repolarization during SA node cell action potential http://purl.obolibrary.org/obo/GO_0086013 membrane repolarization during cardiac muscle cell action potential The process in which an SA node cardiac muscle cell membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential. http://purl.obolibrary.org/obo/GO_0046785 microtubule polymerization http://purl.obolibrary.org/obo/GO_0051258 protein polymerization The addition of tubulin heterodimers to one or both ends of a microtubule. http://purl.obolibrary.org/obo/GO_0086056 voltage-gated calcium channel activity involved in AV node cell action potential http://purl.obolibrary.org/obo/GO_0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential Enables the transmembrane transfer of a calcium ion by a voltage-gated channel across the plasma membrane of an AV node cardiac muscle cell that contributes to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. http://purl.obolibrary.org/obo/GO_0046883 regulation of hormone secretion http://purl.obolibrary.org/obo/GO_1903530 regulation of secretion by cell Any process that modulates the frequency, rate or extent of the regulated release of a hormone from a cell. http://purl.obolibrary.org/obo/GO_0086057 voltage-gated calcium channel activity involved in bundle of His cell action potential http://purl.obolibrary.org/obo/GO_0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential Enables the transmembrane transfer of a calcium ion by a voltage-gated channel across the plasma membrane of a bundle of His cardiac muscle cell that contributes to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. http://purl.obolibrary.org/obo/GO_0046885 regulation of hormone biosynthetic process http://purl.obolibrary.org/obo/GO_0009889 regulation of biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hormones. http://purl.obolibrary.org/obo/GO_0086059 voltage-gated calcium channel activity involved SA node cell action potential http://purl.obolibrary.org/obo/GO_0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential Enables the transmembrane transfer of a calcium ion by a voltage-gated channel across the plasma membrane of an SA node cardiac muscle cell that contributes to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. http://purl.obolibrary.org/obo/GO_0046890 regulation of lipid biosynthetic process http://purl.obolibrary.org/obo/GO_0009889 regulation of biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids. http://purl.obolibrary.org/obo/GO_0086060 voltage-gated sodium channel activity involved in AV node cell action potential http://purl.obolibrary.org/obo/GO_0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential Enables the transmembrane transfer of a sodium ion by a voltage-gated channel through the plasma membrane of an AV node cardiac muscle cell contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. http://purl.obolibrary.org/obo/GO_0046907 intracellular transport http://purl.obolibrary.org/obo/GO_0051641 cellular localization The directed movement of substances within a cell. http://purl.obolibrary.org/obo/GO_0086061 voltage-gated sodium channel activity involved in bundle of His cell action potential http://purl.obolibrary.org/obo/GO_0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential Enables the transmembrane transfer of a sodium ion by a voltage-gated channel through the plasma membrane of a bundle of His cardiac muscle cell contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. http://purl.obolibrary.org/obo/GO_0046914 transition metal ion binding http://purl.obolibrary.org/obo/GO_0046872 metal ion binding Binding to a transition metal ions; a transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver. http://purl.obolibrary.org/obo/GO_0046915 transition metal ion transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0046873 metal ion transmembrane transporter activity Enables the transfer of transition metal ions from one side of a membrane to the other. A transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver. http://purl.obolibrary.org/obo/GO_0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential http://purl.obolibrary.org/obo/GO_0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential Enables the transmembrane transfer of a sodium ion by a voltage-gated channel through the plasma membrane of a Purkinje myocyte contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. http://purl.obolibrary.org/obo/GO_0046930 pore complex http://purl.obolibrary.org/obo/GO_0098796 membrane protein complex A protein complex providing a discrete opening in a membrane that allows the passage of gases and/or liquids. http://purl.obolibrary.org/obo/GO_0086063 voltage-gated sodium channel activity involved in SA node cell action potential http://purl.obolibrary.org/obo/GO_0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential Enables the transmembrane transfer of a sodium ion by a voltage-gated channel through the plasma membrane of an SA node cardiac muscle cell contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. http://purl.obolibrary.org/obo/GO_0046942 carboxylic acid transport http://purl.obolibrary.org/obo/GO_0015849 organic acid transport The directed movement of carboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-). http://purl.obolibrary.org/obo/GO_0086065 cell communication involved in cardiac conduction http://purl.obolibrary.org/obo/GO_0007154 cell communication Any process that mediates interactions between a cell and its surroundings that contributes to the process of cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. http://purl.obolibrary.org/obo/GO_0046943 carboxylic acid transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity Enables the transfer of carboxylic acids from one side of a membrane to the other. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-). http://purl.obolibrary.org/obo/GO_0086066 atrial cardiac muscle cell to AV node cell communication http://purl.obolibrary.org/obo/GO_0086065 cell communication involved in cardiac conduction The process that mediates interactions between an atrial cardiomyocyte and its surroundings that contributes to the process of the atrial cardiomyocyte communicating with an AV node cell in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. http://purl.obolibrary.org/obo/GO_0048029 monosaccharide binding http://purl.obolibrary.org/obo/GO_0036094 small molecule binding Binding to a monosaccharide. Monosaccharides are the simplest carbohydrates; they are polyhydroxy aldehydes H[CH(OH)]nC(=O)H or polyhydroxy ketones H[CHOH]nC(=O)[CHOH]mH with three or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides. http://purl.obolibrary.org/obo/GO_0086067 AV node cell to bundle of His cell communication http://purl.obolibrary.org/obo/GO_0086065 cell communication involved in cardiac conduction The process that mediates interactions between an AV node cell and its surroundings that contributes to the process of the AV node cell communicating with a bundle of His cell in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. http://purl.obolibrary.org/obo/GO_0048066 developmental pigmentation http://purl.obolibrary.org/obo/GO_0043473 pigmentation The developmental process that results in the deposition of coloring matter in an organism, tissue or cell. http://purl.obolibrary.org/obo/GO_0086068 Purkinje myocyte to ventricular cardiac muscle cell communication http://purl.obolibrary.org/obo/GO_0086065 cell communication involved in cardiac conduction The process that mediates interactions between a Purkinje myocyte and its surroundings that contributes to the process of the Purkinje myocyte communicating with a ventricular cardiac muscle cell in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. http://purl.obolibrary.org/obo/GO_0048193 Golgi vesicle transport http://purl.obolibrary.org/obo/GO_0016192 vesicle-mediated transport The directed movement of substances into, out of or within the Golgi apparatus, mediated by vesicles. http://purl.obolibrary.org/obo/GO_0086069 bundle of His cell to Purkinje myocyte communication http://purl.obolibrary.org/obo/GO_0086065 cell communication involved in cardiac conduction The process that mediates interactions between a bundle of His cell and its surroundings that contributes to the process of the bundle of His cell communicating with a Purkinje myocyte in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. http://purl.obolibrary.org/obo/GO_0048232 male gamete generation http://purl.obolibrary.org/obo/GO_0007276 gamete generation Generation of the male gamete; specialised haploid cells produced by meiosis and along with a female gamete takes part in sexual reproduction. http://purl.obolibrary.org/obo/GO_0086070 SA node cell to atrial cardiac muscle cell communication http://purl.obolibrary.org/obo/GO_0086065 cell communication involved in cardiac conduction The process that mediates interactions between an SA node cardiomyocyte and its surroundings that contributes to the process of the SA node cardiomyocyte communicating with an atrial cardiomyocyte in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. http://purl.obolibrary.org/obo/GO_0048477 oogenesis http://purl.obolibrary.org/obo/GO_0007292 female gamete generation The complete process of formation and maturation of an ovum or female gamete from a primordial female germ cell. Examples of this process are found in Mus musculus and Drosophila melanogaster. http://purl.obolibrary.org/obo/GO_0086087 voltage-gated potassium channel activity involved in bundle of His cell action potential repolarization http://purl.obolibrary.org/obo/GO_0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of a bundle of His cell contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. http://purl.obolibrary.org/obo/GO_0048511 rhythmic process http://purl.obolibrary.org/obo/GO_0008150 biological_process Any process pertinent to the generation and maintenance of rhythms in the physiology of an organism. http://purl.obolibrary.org/obo/GO_0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization http://purl.obolibrary.org/obo/GO_0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of an atrial cardiomyocyte contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. http://purl.obolibrary.org/obo/GO_0048515 spermatid differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process whose specific outcome is the progression of a spermatid over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. http://purl.obolibrary.org/obo/GO_0086090 voltage-gated potassium channel activity involved in SA node cell action potential repolarization http://purl.obolibrary.org/obo/GO_0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of an SA node cell contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. http://purl.obolibrary.org/obo/GO_0048523 negative regulation of cellular process http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that stops, prevents, or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. http://purl.obolibrary.org/obo/GO_0086103 G protein-coupled receptor signaling pathway involved in heart process http://purl.obolibrary.org/obo/GO_0007186 G protein-coupled receptor signaling pathway An G protein-coupled receptor signaling pathway which contributes to a circulatory system process carried out by the heart. http://purl.obolibrary.org/obo/GO_0048546 digestive tract morphogenesis http://purl.obolibrary.org/obo/GO_0035239 tube morphogenesis The process in which the anatomical structures of the digestive tract are generated and organized. The digestive tract is the anatomical structure through which food passes and is processed. http://purl.obolibrary.org/obo/GO_0089704 L-glutamate transmembrane export from vacuole http://purl.obolibrary.org/obo/GO_0032974 amino acid transmembrane export from vacuole The directed movement of L-glutamate out of the vacuole, across the vacuolar membrane. http://purl.obolibrary.org/obo/GO_0048565 digestive tract development http://purl.obolibrary.org/obo/GO_0035295 tube development The process whose specific outcome is the progression of the digestive tract over time, from its formation to the mature structure. The digestive tract is the anatomical structure through which food passes and is processed. http://purl.obolibrary.org/obo/GO_0089708 L-histidine transmembrane export from vacuole http://purl.obolibrary.org/obo/GO_1902024 L-histidine transport The directed movement of L-histidine out of the vacuole, across the vacuolar membrane. http://purl.obolibrary.org/obo/GO_0048580 regulation of post-embryonic development http://purl.obolibrary.org/obo/GO_2000026 regulation of multicellular organismal development Any process that modulates the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. http://purl.obolibrary.org/obo/GO_0089718 amino acid import across plasma membrane http://purl.obolibrary.org/obo/GO_0098739 import across plasma membrane The directed movement of an amino acid from outside of a cell, across the plasma membrane and into the cytosol. http://purl.obolibrary.org/obo/GO_0048609 multicellular organismal reproductive process http://purl.obolibrary.org/obo/GO_0022414 reproductive process The process, occurring above the cellular level, that is pertinent to the reproductive function of a multicellular organism. This includes the integrated processes at the level of tissues and organs. http://purl.obolibrary.org/obo/GO_0090009 primitive streak formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The developmental process pertaining to the initial formation of the primitive streak from unspecified parts. The primitive streak is a ridge of cells running along the midline of the embryo where the mesoderm ingresses. It defines the anterior-posterior axis. http://purl.obolibrary.org/obo/GO_0048619 embryonic hindgut morphogenesis http://purl.obolibrary.org/obo/GO_0048598 embryonic morphogenesis The process in which the anatomical structures of the hindgut are generated and organized, during the embryonic phase. http://purl.obolibrary.org/obo/GO_0090022 regulation of neutrophil chemotaxis http://purl.obolibrary.org/obo/GO_0071622 regulation of granulocyte chemotaxis Any process that modulates the frequency, rate, or extent of neutrophil chemotaxis. Neutrophil chemotaxis is the directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding. http://purl.obolibrary.org/obo/GO_0048707 instar larval or pupal morphogenesis http://purl.obolibrary.org/obo/GO_0009886 post-embryonic animal morphogenesis The process, occurring during instar larval or pupal development, by which anatomical structures are generated and organized. http://purl.obolibrary.org/obo/GO_0048753 pigment granule organization http://purl.obolibrary.org/obo/GO_0016050 vesicle organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a pigment granule. http://purl.obolibrary.org/obo/GO_0090023 positive regulation of neutrophil chemotaxis http://purl.obolibrary.org/obo/GO_0071624 positive regulation of granulocyte chemotaxis Any process that increases the frequency, rate, or extent of neutrophil chemotaxis. Neutrophil chemotaxis is the directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding. http://purl.obolibrary.org/obo/GO_0048806 genitalia development http://purl.obolibrary.org/obo/GO_0048608 reproductive structure development The process whose specific outcome is the progression of the genitalia over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0090024 negative regulation of neutrophil chemotaxis http://purl.obolibrary.org/obo/GO_0071623 negative regulation of granulocyte chemotaxis Any process that decreases the frequency, rate, or extent of neutrophil chemotaxis. Neutrophil chemotaxis is the directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding. http://purl.obolibrary.org/obo/GO_0048812 neuron projection morphogenesis http://purl.obolibrary.org/obo/GO_0120039 plasma membrane bounded cell projection morphogenesis The process in which the anatomical structures of a neuron projection are generated and organized. A neuron projection is any process extending from a neural cell, such as axons or dendrites. http://purl.obolibrary.org/obo/GO_0090025 regulation of monocyte chemotaxis http://purl.obolibrary.org/obo/GO_0071675 regulation of mononuclear cell migration Any process that modulates the frequency, rate, or extent of monocyte chemotaxis. http://purl.obolibrary.org/obo/GO_0048859 formation of anatomical boundary http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process in which the limits of an anatomical structure are generated. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome. http://purl.obolibrary.org/obo/GO_0090026 positive regulation of monocyte chemotaxis http://purl.obolibrary.org/obo/GO_0071677 positive regulation of mononuclear cell migration Any process that increases the frequency, rate, or extent of monocyte chemotaxis. http://purl.obolibrary.org/obo/GO_0090027 negative regulation of monocyte chemotaxis http://purl.obolibrary.org/obo/GO_0071676 negative regulation of mononuclear cell migration Any process that decreases the frequency, rate, or extent of monocyte chemotaxis. http://purl.obolibrary.org/obo/GO_0048873 homeostasis of number of cells within a tissue http://purl.obolibrary.org/obo/GO_0048872 homeostasis of number of cells Any biological process involved in the maintenance of the steady-state number of cells within a population of cells in a tissue. http://purl.obolibrary.org/obo/GO_0090063 positive regulation of microtubule nucleation http://purl.obolibrary.org/obo/GO_0010968 regulation of microtubule nucleation Any process that increases the rate, frequency or extent of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell. http://purl.obolibrary.org/obo/GO_0050658 RNA transport http://purl.obolibrary.org/obo/GO_0051236 establishment of RNA localization The directed movement of RNA, ribonucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0090069 regulation of ribosome biogenesis http://purl.obolibrary.org/obo/GO_0044087 regulation of cellular component biogenesis Any process that modulates the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits. http://purl.obolibrary.org/obo/GO_0050768 negative regulation of neurogenesis http://purl.obolibrary.org/obo/GO_0050767 regulation of neurogenesis Any process that stops, prevents, or reduces the frequency, rate or extent of neurogenesis, the generation of cells within the nervous system. http://purl.obolibrary.org/obo/GO_0090070 positive regulation of ribosome biogenesis http://purl.obolibrary.org/obo/GO_0044089 positive regulation of cellular component biogenesis Any process that increases the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits. http://purl.obolibrary.org/obo/GO_0090071 negative regulation of ribosome biogenesis http://purl.obolibrary.org/obo/GO_0090069 regulation of ribosome biogenesis Any process that decreases the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits. http://purl.obolibrary.org/obo/GO_0050801 monoatomic ion homeostasis http://purl.obolibrary.org/obo/GO_0048878 chemical homeostasis Any process involved in the maintenance of an internal steady state of monoatomic ions within an organism or cell. Monatomic ions (also called simple ions) are ions consisting of exactly one atom. http://purl.obolibrary.org/obo/GO_0090078 smooth muscle derived foam cell differentiation http://purl.obolibrary.org/obo/GO_0090077 foam cell differentiation The process in which a smooth muscle cell acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions. http://purl.obolibrary.org/obo/GO_0050817 coagulation http://purl.obolibrary.org/obo/GO_0032501 multicellular organismal process The process in which a fluid solution, or part of it, changes into a solid or semisolid mass. http://purl.obolibrary.org/obo/GO_0090091 positive regulation of extracellular matrix disassembly http://purl.obolibrary.org/obo/GO_0010715 regulation of extracellular matrix disassembly Any process that increases the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix. http://purl.obolibrary.org/obo/GO_0050839 cell adhesion molecule binding http://purl.obolibrary.org/obo/GO_0005515 protein binding Binding to a cell adhesion molecule. http://purl.obolibrary.org/obo/GO_0090102 cochlea development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the cochlea over time from its formation to the mature structure. The cochlea is the snail-shaped portion of the inner ear that is responsible for the detection of sound. http://purl.obolibrary.org/obo/GO_0050890 cognition http://purl.obolibrary.org/obo/GO_0050877 nervous system process The operation of the mind by which an organism becomes aware of objects of thought or perception; it includes the mental activities associated with thinking, learning, and memory. http://purl.obolibrary.org/obo/GO_0090103 cochlea morphogenesis http://purl.obolibrary.org/obo/GO_0048598 embryonic morphogenesis The process in which the cochlea is generated and organized. http://purl.obolibrary.org/obo/GO_0050896 response to stimulus http://purl.obolibrary.org/obo/GO_0008150 biological_process Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism. http://purl.obolibrary.org/obo/GO_0090104 pancreatic epsilon cell differentiation http://purl.obolibrary.org/obo/GO_0035883 enteroendocrine cell differentiation The process in which relatively unspecialized cells acquire specialized structural and functional features of a pancreatic epsilon cell. A pancreatic epsilon cell is a cell in the pancreas that secretes ghrelin. http://purl.obolibrary.org/obo/GO_0050911 detection of chemical stimulus involved in sensory perception of smell http://purl.obolibrary.org/obo/GO_0050907 detection of chemical stimulus involved in sensory perception The series of events involved in the perception of smell in which an olfactory chemical stimulus is received and converted into a molecular signal. http://purl.obolibrary.org/obo/GO_0090105 pancreatic E cell development http://purl.obolibrary.org/obo/GO_0002064 epithelial cell development The process whose specific outcome is the progression of a pancreatic E cell over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0050953 sensory perception of light stimulus http://purl.obolibrary.org/obo/GO_0007600 sensory perception The series of events required for an organism to receive a sensory light stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. http://purl.obolibrary.org/obo/GO_0090138 regulation of actin cytoskeleton organization by cell-cell adhesion http://purl.obolibrary.org/obo/GO_0098609 cell-cell adhesion Any cell-cell adhesion process that modulates the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins. http://purl.obolibrary.org/obo/GO_0050954 sensory perception of mechanical stimulus http://purl.obolibrary.org/obo/GO_0007600 sensory perception The series of events required for an organism to receive a sensory mechanical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. http://purl.obolibrary.org/obo/GO_0090139 mitochondrial chromosome packaging http://purl.obolibrary.org/obo/GO_0051276 chromosome organization A process in which mitochondrial chromosomal DNA and associated proteins organize into a compact, orderly structure. http://purl.obolibrary.org/obo/GO_0051031 tRNA transport http://purl.obolibrary.org/obo/GO_0050658 RNA transport The directed movement of tRNA, transfer ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0090140 regulation of mitochondrial fission http://purl.obolibrary.org/obo/GO_0010821 regulation of mitochondrion organization Any process that modulates the rate, frequency or extent of mitochondrial fission. Mitochondrial fission is the division of a mitochondrion within a cell to form two or more separate mitochondrial compartments. http://purl.obolibrary.org/obo/GO_0051053 negative regulation of DNA metabolic process http://purl.obolibrary.org/obo/GO_0045934 negative regulation of nucleobase-containing compound metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving DNA. http://purl.obolibrary.org/obo/GO_0090141 positive regulation of mitochondrial fission http://purl.obolibrary.org/obo/GO_0010638 positive regulation of organelle organization Any process that increases the rate, frequency or extent of mitochondrial fission. Mitochondrial fission is the division of a mitochondrion within a cell to form two or more separate mitochondrial compartments. http://purl.obolibrary.org/obo/GO_0051081 nuclear membrane disassembly http://purl.obolibrary.org/obo/GO_0030397 membrane disassembly The controlled breakdown of the nuclear membranes, for example during cellular division. http://purl.obolibrary.org/obo/GO_0090153 regulation of sphingolipid biosynthetic process http://purl.obolibrary.org/obo/GO_0010556 regulation of macromolecule biosynthetic process Any process that modulates the rate, frequency or extent of sphingolipid biosynthesis. Sphingolipid biosynthesis is the chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid). http://purl.obolibrary.org/obo/GO_0051119 sugar transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0015144 carbohydrate transmembrane transporter activity Enables the transfer of a sugar from one side of a membrane to the other. A sugar is any member of a class of sweet, water-soluble, crystallizable carbohydrates, which are the monosaccharides and smaller oligosaccharides. http://purl.obolibrary.org/obo/GO_0090154 positive regulation of sphingolipid biosynthetic process http://purl.obolibrary.org/obo/GO_0046889 positive regulation of lipid biosynthetic process Any process that increases the rate, frequency or extent of sphingolipid biosynthesis. Sphingolipid biosynthesis is the chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid). http://purl.obolibrary.org/obo/GO_0051168 nuclear export http://purl.obolibrary.org/obo/GO_0006913 nucleocytoplasmic transport The directed movement of substances out of the nucleus. http://purl.obolibrary.org/obo/GO_0090155 negative regulation of sphingolipid biosynthetic process http://purl.obolibrary.org/obo/GO_0051055 negative regulation of lipid biosynthetic process Any process that decreases the rate, frequency or extent of sphingolipid biosynthesis. Sphingolipid biosynthesis is the chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid). http://purl.obolibrary.org/obo/GO_0051169 nuclear transport http://purl.obolibrary.org/obo/GO_0046907 intracellular transport The directed movement of substances into, out of, or within the nucleus. http://purl.obolibrary.org/obo/GO_0090156 intracellular sphingolipid homeostasis http://purl.obolibrary.org/obo/GO_0055088 lipid homeostasis A homeostatic process involved in the maintenance of a steady state level of sphingolipids within a cell. http://purl.obolibrary.org/obo/GO_0051170 import into nucleus http://purl.obolibrary.org/obo/GO_0006913 nucleocytoplasmic transport The directed movement of substances into the nucleus. http://purl.obolibrary.org/obo/GO_0090160 Golgi to lysosome transport http://purl.obolibrary.org/obo/GO_0016482 cytosolic transport The directed movement of substances from the Golgi to lysosomes. http://purl.obolibrary.org/obo/GO_0051234 establishment of localization http://purl.obolibrary.org/obo/GO_0051179 localization Any process that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation. http://purl.obolibrary.org/obo/GO_0090166 Golgi disassembly http://purl.obolibrary.org/obo/GO_1903008 organelle disassembly A cellular process that results in the breakdown of a Golgi apparatus that contributes to Golgi inheritance. http://purl.obolibrary.org/obo/GO_0051261 protein depolymerization http://purl.obolibrary.org/obo/GO_0032984 protein-containing complex disassembly The process in which protein polymers, compounds composed of a large number of component monomers, are broken down. Depolymerization occurs by the successive removal of monomers from an existing poly- or oligomeric protein. http://purl.obolibrary.org/obo/GO_0090170 regulation of Golgi inheritance http://purl.obolibrary.org/obo/GO_1903358 regulation of Golgi organization Any process that modulates the rate, frequency or extent of Golgi inheritance. Golgi inheritance is the partitioning of Golgi apparatus between daughter cells at cell division. http://purl.obolibrary.org/obo/GO_0051378 serotonin binding http://purl.obolibrary.org/obo/GO_0043169 cation binding Binding to serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties. http://purl.obolibrary.org/obo/GO_0090190 positive regulation of branching involved in ureteric bud morphogenesis http://purl.obolibrary.org/obo/GO_0090189 regulation of branching involved in ureteric bud morphogenesis Any process that increases the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules. http://purl.obolibrary.org/obo/GO_0051381 histamine binding http://purl.obolibrary.org/obo/GO_0043169 cation binding Binding to histamine, a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans. http://purl.obolibrary.org/obo/GO_0090258 negative regulation of mitochondrial fission http://purl.obolibrary.org/obo/GO_0010639 negative regulation of organelle organization Any process that decreases the rate, frequency or extent of mitochondrial fission. Mitochondrial fission is the division of a mitochondrion within a cell to form two or more separate mitochondrial compartments. http://purl.obolibrary.org/obo/GO_0051592 response to calcium ion http://purl.obolibrary.org/obo/GO_0010038 response to metal ion Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus. http://purl.obolibrary.org/obo/GO_0090273 regulation of somatostatin secretion http://purl.obolibrary.org/obo/GO_0090276 regulation of peptide hormone secretion Any process that modulates the rate, frequency, extent of the regulated release of somatostatin from secretory granules in the D cells of the pancreas. http://purl.obolibrary.org/obo/GO_0051604 protein maturation http://purl.obolibrary.org/obo/GO_0019538 protein metabolic process Any process leading to the attainment of the full functional capacity of a protein. http://purl.obolibrary.org/obo/GO_0090274 positive regulation of somatostatin secretion http://purl.obolibrary.org/obo/GO_0090273 regulation of somatostatin secretion Any process that increases the rate, frequency, extent of the regulated release of somatostatin from secretory granules in the D cells of the pancreas. http://purl.obolibrary.org/obo/GO_0051649 establishment of localization in cell http://purl.obolibrary.org/obo/GO_0051234 establishment of localization Any process, occurring in a cell, that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation. http://purl.obolibrary.org/obo/GO_0090275 negative regulation of somatostatin secretion http://purl.obolibrary.org/obo/GO_0090273 regulation of somatostatin secretion Any process that decreases the rate, frequency, extent of the regulated release of somatostatin from secretory granules in the D cells of the pancreas. http://purl.obolibrary.org/obo/GO_0051650 establishment of vesicle localization http://purl.obolibrary.org/obo/GO_0051656 establishment of organelle localization The directed movement of a vesicle to a specific location. http://purl.obolibrary.org/obo/GO_0090289 regulation of osteoclast proliferation http://purl.obolibrary.org/obo/GO_0070663 regulation of leukocyte proliferation Any process that modulates the rate, frequency, or extent of the multiplication or reproduction of osteoclasts, resulting in the expansion of an osteoclast cell population. http://purl.obolibrary.org/obo/GO_0051651 maintenance of location in cell http://purl.obolibrary.org/obo/GO_0051235 maintenance of location Any process in which a substance or cellular entity, such as a protein complex or organelle, is maintained in a specific location within, or in the membrane of, a cell, and is prevented from moving elsewhere. http://purl.obolibrary.org/obo/GO_0090290 positive regulation of osteoclast proliferation http://purl.obolibrary.org/obo/GO_0090289 regulation of osteoclast proliferation Any process that increases the rate, frequency, or extent of the multiplication or reproduction of osteoclasts, resulting in the expansion of an osteoclast cell population. http://purl.obolibrary.org/obo/GO_0051716 cellular response to stimulus http://purl.obolibrary.org/obo/GO_0009987 cellular process Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus by a cell and ends with a change in state or activity or the cell. http://purl.obolibrary.org/obo/GO_0090291 negative regulation of osteoclast proliferation http://purl.obolibrary.org/obo/GO_0090289 regulation of osteoclast proliferation Any process that decreases the rate, frequency, or extent of the multiplication or reproduction of osteoclasts, resulting in the expansion of an osteoclast cell population. http://purl.obolibrary.org/obo/GO_0051783 regulation of nuclear division http://purl.obolibrary.org/obo/GO_0033043 regulation of organelle organization Any process that modulates the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information. http://purl.obolibrary.org/obo/GO_0090299 regulation of neural crest formation http://purl.obolibrary.org/obo/GO_0010717 regulation of epithelial to mesenchymal transition Any process that modulates the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation proceeds. http://purl.obolibrary.org/obo/GO_0055074 calcium ion homeostasis http://purl.obolibrary.org/obo/GO_0098771 inorganic ion homeostasis Any process involved in the maintenance of an internal steady state of calcium ions within an organism or cell. http://purl.obolibrary.org/obo/GO_0090300 positive regulation of neural crest formation http://purl.obolibrary.org/obo/GO_0010718 positive regulation of epithelial to mesenchymal transition Any process that increases the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation proceeds. http://purl.obolibrary.org/obo/GO_0055078 sodium ion homeostasis http://purl.obolibrary.org/obo/GO_0098771 inorganic ion homeostasis Any process involved in the maintenance of an internal steady state of sodium ions within an organism or cell. http://purl.obolibrary.org/obo/GO_0090301 negative regulation of neural crest formation http://purl.obolibrary.org/obo/GO_0010719 negative regulation of epithelial to mesenchymal transition Any process that decreases the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation proceeds. http://purl.obolibrary.org/obo/GO_0055085 transmembrane transport http://purl.obolibrary.org/obo/GO_0009987 cellular process The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0090325 regulation of locomotion involved in locomotory behavior http://purl.obolibrary.org/obo/GO_0040012 regulation of locomotion Any process that modulates the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement. http://purl.obolibrary.org/obo/GO_0055086 nucleobase-containing small molecule metabolic process http://purl.obolibrary.org/obo/GO_0044281 small molecule metabolic process The cellular chemical reactions and pathways involving a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide. http://purl.obolibrary.org/obo/GO_0090326 positive regulation of locomotion involved in locomotory behavior http://purl.obolibrary.org/obo/GO_0048520 positive regulation of behavior Any process that increases the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement. http://purl.obolibrary.org/obo/GO_0060004 reflex http://purl.obolibrary.org/obo/GO_0009605 response to external stimulus An automatic response to a stimulus beginning with a nerve impulse from a receptor and ending with the action of an effector such as a gland or a muscle. Signaling never reaches a level of consciousness. http://purl.obolibrary.org/obo/GO_0090327 negative regulation of locomotion involved in locomotory behavior http://purl.obolibrary.org/obo/GO_0090325 regulation of locomotion involved in locomotory behavior Any process that decreases the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement. http://purl.obolibrary.org/obo/GO_0060047 heart contraction http://purl.obolibrary.org/obo/GO_0003015 heart process The multicellular organismal process in which the heart decreases in volume in a characteristic way to propel blood through the body. http://purl.obolibrary.org/obo/GO_0060079 excitatory postsynaptic potential http://purl.obolibrary.org/obo/GO_0060078 regulation of postsynaptic membrane potential A process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential. http://purl.obolibrary.org/obo/GO_0090328 regulation of olfactory learning http://purl.obolibrary.org/obo/GO_0050795 regulation of behavior Any process that modulates the rate, frequency, or extent of olfactory learning. Olfactory learning is any process in an organism in which a relatively long-lasting adaptive behavioral change occurs in response to (repeated) exposure to an olfactory cue. http://purl.obolibrary.org/obo/GO_0060089 molecular transducer activity http://purl.obolibrary.org/obo/GO_0003674 molecular_function A compound molecular function in which an effector function is controlled by one or more regulatory components. http://purl.obolibrary.org/obo/GO_0090335 regulation of brown fat cell differentiation http://purl.obolibrary.org/obo/GO_0045598 regulation of fat cell differentiation Any process that modulates the rate, frequency, or extent of brown fat cell differentiation. Brown fat cell differentiation is the process in which a relatively unspecialized cell acquires specialized features of a brown adipocyte, an animal connective tissue cell involved in adaptive thermogenesis. Brown adipocytes contain multiple small droplets of triglycerides and a high number of mitochondria. http://purl.obolibrary.org/obo/GO_0060156 milk ejection reflex http://purl.obolibrary.org/obo/GO_0032941 secretion by tissue A reflex that occurs in response to suckling, beginning with a nerve impulse from a receptor in the mammary gland and ending with the ejection of milk from the gland. Signaling never reaches a level of consciousness. http://purl.obolibrary.org/obo/GO_0060281 regulation of oocyte development http://purl.obolibrary.org/obo/GO_1905879 regulation of oogenesis Any process that modulates the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell. http://purl.obolibrary.org/obo/GO_0090336 positive regulation of brown fat cell differentiation http://purl.obolibrary.org/obo/GO_0090335 regulation of brown fat cell differentiation Any process that increases the rate, frequency, or extent of brown fat cell differentiation. Brown fat cell differentiation is the process in which a relatively unspecialized cell acquires specialized features of a brown adipocyte, an animal connective tissue cell involved in adaptive thermogenesis. Brown adipocytes contain multiple small droplets of triglycerides and a high number of mitochondria. http://purl.obolibrary.org/obo/GO_0060322 head development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The biological process whose specific outcome is the progression of a head from an initial condition to its mature state. The head is the anterior-most division of the body. http://purl.obolibrary.org/obo/GO_0060326 cell chemotaxis http://purl.obolibrary.org/obo/GO_0016477 cell migration The directed movement of a motile cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis). http://purl.obolibrary.org/obo/GO_0090394 negative regulation of excitatory postsynaptic potential http://purl.obolibrary.org/obo/GO_0098815 modulation of excitatory postsynaptic potential Any process that prevents the establishment or decreases the extent of the excitatory postsynaptic potential (EPSP) which is a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential. http://purl.obolibrary.org/obo/GO_0060327 cytoplasmic actin-based contraction involved in cell motility http://purl.obolibrary.org/obo/GO_0070252 actin-mediated cell contraction The actin filament-based movement by which cytoplasmic actin filaments slide past one another resulting in a contraction that propels the cell from one place to another. http://purl.obolibrary.org/obo/GO_0090454 glutamate transmembrane import into vacuole http://purl.obolibrary.org/obo/GO_0015800 acidic amino acid transport The directed movement of glutamate into the vacuole across the vacuolar membrane. http://purl.obolibrary.org/obo/GO_0060404 axonemal microtubule depolymerization http://purl.obolibrary.org/obo/GO_0061523 cilium disassembly The removal of tubulin heterodimers from one or both ends of an axonemal microtubule. An axonemal microtubule is a microtubule in the axoneme of a cilium or flagellum; an axoneme contains nine modified doublet microtubules surrounding a pair of single microtubules. http://purl.obolibrary.org/obo/GO_0090461 intracellular glutamate homeostasis http://purl.obolibrary.org/obo/GO_0080144 intracellular amino acid homeostasis A homeostatic process involved in the maintenance of a steady state level of glutamate within a cell. http://purl.obolibrary.org/obo/GO_0060446 branching involved in open tracheal system development http://purl.obolibrary.org/obo/GO_0048754 branching morphogenesis of an epithelial tube The process in which the anatomical structures of branches in the open tracheal system are generated and organized. http://purl.obolibrary.org/obo/GO_0060541 respiratory system development http://purl.obolibrary.org/obo/GO_0048731 system development The progression of the respiratory system over time from its formation to its mature structure. The respiratory system carries out respiratory gaseous exchange. http://purl.obolibrary.org/obo/GO_0090513 L-histidine transmembrane import into vacuole http://purl.obolibrary.org/obo/GO_1902024 L-histidine transport The directed movement of L-histidine into the vacuole across the vacuolar membrane. http://purl.obolibrary.org/obo/GO_0060612 adipose tissue development http://purl.obolibrary.org/obo/GO_0061448 connective tissue development The process whose specific outcome is the progression of adipose tissue over time, from its formation to the mature structure. Adipose tissue is specialized tissue that is used to store fat. http://purl.obolibrary.org/obo/GO_0090515 L-glutamate transmembrane import into vacuole http://purl.obolibrary.org/obo/GO_0090454 glutamate transmembrane import into vacuole The directed movement of L-glutamate into the vacuole across the vacuolar membrane. http://purl.obolibrary.org/obo/GO_0061024 membrane organization http://purl.obolibrary.org/obo/GO_0016043 cellular component organization A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane. A membrane is a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins. http://purl.obolibrary.org/obo/GO_0061061 muscle structure development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of a muscle structure over time, from its formation to its mature state. Muscle structures are contractile cells, tissues or organs that are found in multicellular organisms. http://purl.obolibrary.org/obo/GO_0090521 podocyte cell migration http://purl.obolibrary.org/obo/GO_0010631 epithelial cell migration The orderly movement of a podocyte from one site to another, often during the development of a multicellular organism or multicellular structure. A podocyte is a specialized kidney epithelial cell. http://purl.obolibrary.org/obo/GO_0061320 pericardial nephrocyte differentiation http://purl.obolibrary.org/obo/GO_0061319 nephrocyte differentiation The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a pericardial nephrocyte. A pericardial nephrocyte is an insect renal cell that filters hemolymph and is found with other pericardial nephrocytes in two rows flanking the dorsal vessel. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. http://purl.obolibrary.org/obo/GO_0090634 microglial cell mediated cytotoxicity http://purl.obolibrary.org/obo/GO_0002444 myeloid leukocyte mediated immunity The directed killing of a target cell by a microglial cell. http://purl.obolibrary.org/obo/GO_0061321 garland nephrocyte differentiation http://purl.obolibrary.org/obo/GO_0061319 nephrocyte differentiation The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a garland nephrocyte. A garland nephrocyte is an insect renal cell that filters hemolymph and forms a ring with other garland nephrocytes around the esophagus. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. http://purl.obolibrary.org/obo/GO_0090685 RNA localization to nucleus http://purl.obolibrary.org/obo/GO_0006403 RNA localization A macromolecular localization process in which RNA is transported to and maintained in a location within the nucleus. http://purl.obolibrary.org/obo/GO_0061333 renal tubule morphogenesis http://purl.obolibrary.org/obo/GO_0060562 epithelial tube morphogenesis The process in which the renal tubule is generated by specification of cell fate, through the maintenance of cell polarity, regulated cell proliferation and morphogenetic cell rearrangements, shape changes and growth. A renal tubule is a tube that filters, re-absorbs and secretes substances to rid an organism of waste and to play a role in fluid homeostasis. http://purl.obolibrary.org/obo/GO_0090713 immunological memory process http://purl.obolibrary.org/obo/GO_0002376 immune system process Any process of the immune system that can contribute to the formation of immunological memory or an immune response based upon activation of immunological memory. http://purl.obolibrary.org/obo/GO_0061351 neural precursor cell proliferation http://purl.obolibrary.org/obo/GO_0008283 cell population proliferation The multiplication or reproduction of neural precursor cells, resulting in the expansion of a cell population. A neural precursor cell is either a nervous system stem cell or a nervous system progenitor cell. http://purl.obolibrary.org/obo/GO_0097026 dendritic cell dendrite assembly http://purl.obolibrary.org/obo/GO_0120031 plasma membrane bounded cell projection assembly Formation of dendrites, branched cellular projections (or cytoplasmic extension) that are extended from the surface of a dendritic immune cell, and which enable the cell to sample luminal pathogens and increase the surface area for antigen presentation to T cells. http://purl.obolibrary.org/obo/GO_0061462 protein localization to lysosome http://purl.obolibrary.org/obo/GO_0072665 protein localization to vacuole A process in which a protein is transported to, or maintained in, a location within a lysosome. http://purl.obolibrary.org/obo/GO_0097029 mature conventional dendritic cell differentiation http://purl.obolibrary.org/obo/GO_0097028 dendritic cell differentiation The process in which antigen-activated dendritic cells acquire the specialized features of a mature conventional dendritic cell. Mature conventional dendritic cells upregulate the surface expression of MHC molecules, chemokine receptors and adhesion molecules, and increase the number of dendrites (cytoplasmic protrusions) in preparation for migration to lymphoid organs where they present antigen to T cells. http://purl.obolibrary.org/obo/GO_0061525 hindgut development http://purl.obolibrary.org/obo/GO_0048565 digestive tract development The process whose specific outcome is the progression of the hindgut over time, from its formation to the mature structure. The hindgut is part of the alimentary canal that lies posterior to the midgut. http://purl.obolibrary.org/obo/GO_0097048 dendritic cell apoptotic process http://purl.obolibrary.org/obo/GO_0071887 leukocyte apoptotic process Any apoptotic process in a dendritic cell, a cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation. http://purl.obolibrary.org/obo/GO_0061564 axon development http://purl.obolibrary.org/obo/GO_0031175 neuron projection development The progression of an axon over time. Covers axonogenesis (de novo generation of an axon) and axon regeneration (regrowth), as well as processes pertaining to the progression of the axon over time (fasciculation and defasciculation). http://purl.obolibrary.org/obo/GO_0097049 motor neuron apoptotic process http://purl.obolibrary.org/obo/GO_0051402 neuron apoptotic process Any apoptotic process in a motor neuron, an efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes movement. http://purl.obolibrary.org/obo/GO_0065002 intracellular protein transmembrane transport http://purl.obolibrary.org/obo/GO_0071806 protein transmembrane transport The directed movement of proteins in a cell, from one side of a membrane to another by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0097050 type B pancreatic cell apoptotic process http://purl.obolibrary.org/obo/GO_1904019 epithelial cell apoptotic process Any apoptotic process in a type B pancreatic cell, a cell located towards center of the islets of Langerhans that secretes insulin. http://purl.obolibrary.org/obo/GO_0065003 protein-containing complex assembly http://purl.obolibrary.org/obo/GO_0043933 protein-containing complex organization The aggregation, arrangement and bonding together of a set of macromolecules to form a protein-containing complex. http://purl.obolibrary.org/obo/GO_0097054 L-glutamate biosynthetic process http://purl.obolibrary.org/obo/GO_0043650 dicarboxylic acid biosynthetic process The chemical reactions and pathways resulting in the formation of L-glutamate, the L enantiomer anion of 2-aminopentanedioic acid. http://purl.obolibrary.org/obo/GO_0070013 intracellular organelle lumen http://purl.obolibrary.org/obo/GO_0043233 organelle lumen An organelle lumen that is part of an intracellular organelle. http://purl.obolibrary.org/obo/GO_0097086 amniotic stem cell differentiation http://purl.obolibrary.org/obo/GO_0072497 mesenchymal stem cell differentiation The process whereby a relatively unspecialized cell acquires specialized features of an amniotic stem cell. An amniotic stem cell is a mesenchymal stem cell extracted from amniotic fluid. Amniotic stem cells are able to differentiate into various tissue types such as skin, cartilage, cardiac tissue, nerves, muscle, and bone. http://purl.obolibrary.org/obo/GO_0070160 tight junction http://purl.obolibrary.org/obo/GO_0005911 cell-cell junction A cell-cell junction that seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other. http://purl.obolibrary.org/obo/GO_0097096 facial suture morphogenesis http://purl.obolibrary.org/obo/GO_0097094 craniofacial suture morphogenesis The process in which any suture between facial bones is generated and organized. http://purl.obolibrary.org/obo/GO_0070161 anchoring junction http://purl.obolibrary.org/obo/GO_0030054 cell junction A cell junction that mechanically attaches a cell (and its cytoskeleton) to neighboring cells or to the extracellular matrix. http://purl.obolibrary.org/obo/GO_0097104 postsynaptic membrane assembly http://purl.obolibrary.org/obo/GO_0071709 membrane assembly The aggregation, arrangement and bonding together of a set of components to form a postsynaptic membrane, a specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). http://purl.obolibrary.org/obo/GO_0070192 chromosome organization involved in meiotic cell cycle http://purl.obolibrary.org/obo/GO_1903046 meiotic cell cycle process A process of chromosome organization that is involved in a meiotic cell cycle. http://purl.obolibrary.org/obo/GO_0097120 receptor localization to synapse http://purl.obolibrary.org/obo/GO_0051179 localization Any process in which a receptor is transported to, and/or maintained at the synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell. http://purl.obolibrary.org/obo/GO_0070231 T cell apoptotic process http://purl.obolibrary.org/obo/GO_0070227 lymphocyte apoptotic process Any apoptotic process in a T cell, a type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex. http://purl.obolibrary.org/obo/GO_0070382 exocytic vesicle http://purl.obolibrary.org/obo/GO_0099503 secretory vesicle A transport vesicle that mediates transport from an intracellular compartment to the plasma membrane, and fuses with the plasma membrane to release various cargo molecules, such as proteins or hormones, by exocytosis. http://purl.obolibrary.org/obo/GO_0097152 mesenchymal cell apoptotic process http://purl.obolibrary.org/obo/GO_0006915 apoptotic process Any apoptotic process in a mesenchymal cell. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types. http://purl.obolibrary.org/obo/GO_0097177 mitochondrial ribosome binding http://purl.obolibrary.org/obo/GO_0043022 ribosome binding Binding to a mitochondrial ribosome. http://purl.obolibrary.org/obo/GO_0070588 calcium ion transmembrane transport http://purl.obolibrary.org/obo/GO_0098655 monoatomic cation transmembrane transport A process in which a calcium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0070851 growth factor receptor binding http://purl.obolibrary.org/obo/GO_0005102 signaling receptor binding Binding to a growth factor receptor. http://purl.obolibrary.org/obo/GO_0097187 dentinogenesis http://purl.obolibrary.org/obo/GO_0042475 odontogenesis of dentin-containing tooth The process whose specific outcome is the formation of dentin, the mineralized tissue that constitutes the major bulk of teeth. Dentin may be one of three types: primary dentin, secondary dentin, and tertiary dentin. http://purl.obolibrary.org/obo/GO_0070873 regulation of glycogen metabolic process http://purl.obolibrary.org/obo/GO_0032881 regulation of polysaccharide metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving glycogen. http://purl.obolibrary.org/obo/GO_0097208 alveolar lamellar body http://purl.obolibrary.org/obo/GO_0042599 lamellar body A specialized secretory organelle found in type II pneumocytes and involved in the synthesis, secretion, and reutilization of pulmonary surfactant. http://purl.obolibrary.org/obo/GO_0071377 cellular response to glucagon stimulus http://purl.obolibrary.org/obo/GO_0071375 cellular response to peptide hormone stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucagon stimulus. http://purl.obolibrary.org/obo/GO_0071705 nitrogen compound transport http://purl.obolibrary.org/obo/GO_0006810 transport The directed movement of nitrogen-containing compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0097209 epidermal lamellar body http://purl.obolibrary.org/obo/GO_0042599 lamellar body A specialized secretory organelle found in keratinocytes and involved in the formation of an impermeable, lipid-containing membrane that serves as a water barrier and is required for correct skin barrier function. http://purl.obolibrary.org/obo/GO_0071805 potassium ion transmembrane transport http://purl.obolibrary.org/obo/GO_0098655 monoatomic cation transmembrane transport A process in which a potassium ion is transported from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0097212 lysosomal membrane organization http://purl.obolibrary.org/obo/GO_0061024 membrane organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lysosomal membrane. A lysosomal membrane is the lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm. http://purl.obolibrary.org/obo/GO_0071813 lipoprotein particle binding http://purl.obolibrary.org/obo/GO_0071814 protein-lipid complex binding Binding to a lipoprotein particle. A lipoprotein particle, also known as a lipoprotein, is a clathrate complex consisting of a lipid enwrapped in a protein host without covalent binding in such a way that the complex has a hydrophilic outer surface consisting of all the protein and the polar ends of any phospholipids. http://purl.obolibrary.org/obo/GO_0071944 cell periphery http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures. http://purl.obolibrary.org/obo/GO_0072002 Malpighian tubule development http://purl.obolibrary.org/obo/GO_0061326 renal tubule development The process whose specific outcome is the progression of the Malpighian tubule over time, from its formation to the mature structure. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which leads into the posterior part of the gut. http://purl.obolibrary.org/obo/GO_0072089 stem cell proliferation http://purl.obolibrary.org/obo/GO_0008283 cell population proliferation The multiplication or reproduction of stem cells, resulting in the expansion of a stem cell population. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells. http://purl.obolibrary.org/obo/GO_0097232 lamellar body membrane http://purl.obolibrary.org/obo/GO_0030667 secretory granule membrane The lipid bilayer surrounding a lamellar body. A lamellar body is a membrane-bounded organelle, specialized for the storage and secretion of various substances (surfactant phospholipids, glycoproteins and acid phosphates) which are arranged in the form of tightly packed, concentric, membrane sheets or lamellae. Has some similar properties to, but is distinct from, a lysosome. http://purl.obolibrary.org/obo/GO_0072329 monocarboxylic acid catabolic process http://purl.obolibrary.org/obo/GO_0046395 carboxylic acid catabolic process The chemical reactions and pathways resulting in the breakdown of monocarboxylic acids, any organic acid containing one carboxyl (-COOH) group. http://purl.obolibrary.org/obo/GO_0097233 alveolar lamellar body membrane http://purl.obolibrary.org/obo/GO_0097232 lamellar body membrane The lipid bilayer surrounding an alveolar lamellar body, a specialized secretory organelle found in type II pneumocytes and involved in the synthesis, secretion, and reutilization of pulmonary surfactant. http://purl.obolibrary.org/obo/GO_0072359 circulatory system development http://purl.obolibrary.org/obo/GO_0048731 system development The process whose specific outcome is the progression of the circulatory system over time, from its formation to the mature structure. The circulatory system is the organ system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells, etc. to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis. http://purl.obolibrary.org/obo/GO_0097234 epidermal lamellar body membrane http://purl.obolibrary.org/obo/GO_0097232 lamellar body membrane The lipid bilayer surrounding an epidermal lamellar body, a specialized secretory organelle found in keratinocytes and involved in the formation of an impermeable, lipid-containing membrane that serves as a water barrier and is required for correct skin barrier function. http://purl.obolibrary.org/obo/GO_0072521 purine-containing compound metabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process The chemical reactions and pathways involving a purine-containing compound, i.e. any compound that contains purine or a formal derivative thereof. http://purl.obolibrary.org/obo/GO_0097252 oligodendrocyte apoptotic process http://purl.obolibrary.org/obo/GO_0034349 glial cell apoptotic process Any apoptotic process in an oligodendrocyte. Oligodendrocytes belong to a class of large neuroglial (macroglial) cells in the central nervous system, where they form the insulating myelin sheath of axons. http://purl.obolibrary.org/obo/GO_0072522 purine-containing compound biosynthetic process http://purl.obolibrary.org/obo/GO_0009058 biosynthetic process The chemical reactions and pathways resulting in the formation of a purine-containing compound, i.e. any compound that contains purine or a formal derivative thereof. http://purl.obolibrary.org/obo/GO_0097254 renal tubular secretion http://purl.obolibrary.org/obo/GO_0003014 renal system process The elimination of substances from peritubular capillaries (or surrounding hemolymph in invertebrates) into the renal tubules to be incorporated subsequently into the urine. Substances that are secreted include organic anions, ammonia, potassium and drugs. http://purl.obolibrary.org/obo/GO_0072523 purine-containing compound catabolic process http://purl.obolibrary.org/obo/GO_0009056 catabolic process The chemical reactions and pathways resulting in the breakdown of a purine-containing compound, i.e. any compound that contains purine or a formal derivative thereof. http://purl.obolibrary.org/obo/GO_0097272 ammonium homeostasis http://purl.obolibrary.org/obo/GO_0098771 inorganic ion homeostasis Any biological process involved in the maintenance of an internal steady state of ammonium. http://purl.obolibrary.org/obo/GO_0072594 establishment of protein localization to organelle http://purl.obolibrary.org/obo/GO_0045184 establishment of protein localization The directed movement of a protein to a specific location on or in an organelle. Encompasses establishment of localization in the membrane or lumen of a membrane-bounded organelle. http://purl.obolibrary.org/obo/GO_0097275 intracellular ammonium homeostasis http://purl.obolibrary.org/obo/GO_0097272 ammonium homeostasis A homeostatic process involved in the maintenance of a steady state level of ammonium within a cell. http://purl.obolibrary.org/obo/GO_0072666 establishment of protein localization to vacuole http://purl.obolibrary.org/obo/GO_0072594 establishment of protein localization to organelle The directed movement of a protein to a specific location in a vacuole. http://purl.obolibrary.org/obo/GO_0097283 keratinocyte apoptotic process http://purl.obolibrary.org/obo/GO_1904019 epithelial cell apoptotic process Any apoptotic process in a keratinocyte. A keratinocyte is an epidermal cell which synthesizes keratin and undergoes a characteristic change as it moves upward from the basal layers of the epidermis to the cornified (horny) layer of the skin. http://purl.obolibrary.org/obo/GO_0080090 regulation of primary metabolic process http://purl.obolibrary.org/obo/GO_0019222 regulation of metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism involving those compounds formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism. http://purl.obolibrary.org/obo/GO_0097284 hepatocyte apoptotic process http://purl.obolibrary.org/obo/GO_1904019 epithelial cell apoptotic process Any apoptotic process in a hepatocyte, the main structural component of the liver. http://purl.obolibrary.org/obo/GO_0080171 lytic vacuole organization http://purl.obolibrary.org/obo/GO_0007033 vacuole organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lytic vacuole. http://purl.obolibrary.org/obo/GO_0097324 melanocyte migration http://purl.obolibrary.org/obo/GO_0010631 epithelial cell migration The orderly movement of melanocytes from one site to another, often during the development of a multicellular organism. A melanocyte is a pigment cell derived from the neural crest. It contains melanin-filled pigment granules, which give a brown to black appearance. http://purl.obolibrary.org/obo/GO_0089709 L-histidine transmembrane transport http://purl.obolibrary.org/obo/GO_1902475 L-alpha-amino acid transmembrane transport The directed movement of L-histidine across a membrane. http://purl.obolibrary.org/obo/GO_0097360 chorionic trophoblast cell proliferation http://purl.obolibrary.org/obo/GO_0008283 cell population proliferation The multiplication or reproduction of chorionic trophoblast cells, resulting in the expansion of their population. http://purl.obolibrary.org/obo/GO_0090030 regulation of steroid hormone biosynthetic process http://purl.obolibrary.org/obo/GO_0050810 regulation of steroid biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroid hormones,compounds with a 1, 2, cyclopentanoperhydrophenanthrene nucleus that act as hormones. http://purl.obolibrary.org/obo/GO_0097386 glial cell projection http://purl.obolibrary.org/obo/GO_0120025 plasma membrane bounded cell projection A prolongation or process extending from a glial cell. http://purl.obolibrary.org/obo/GO_0090130 tissue migration http://purl.obolibrary.org/obo/GO_0032501 multicellular organismal process The process in which the population of cells that make up a tissue undergo directed movement. http://purl.obolibrary.org/obo/GO_0097402 neuroblast migration http://purl.obolibrary.org/obo/GO_0016477 cell migration The orderly movement of a neuroblast from one site to another, often during the development of a multicellular organism or multicellular structure. A neuroblast is any cell that will divide and give rise to a neuron. http://purl.obolibrary.org/obo/GO_0090150 establishment of protein localization to membrane http://purl.obolibrary.org/obo/GO_0045184 establishment of protein localization The directed movement of a protein to a specific location in a membrane. http://purl.obolibrary.org/obo/GO_0097410 hippocampal interneuron differentiation http://purl.obolibrary.org/obo/GO_0021895 cerebral cortex neuron differentiation The process in which a relatively unspecialized cell acquires specialized features of a hippocampal interneuron. http://purl.obolibrary.org/obo/GO_0090257 regulation of muscle system process http://purl.obolibrary.org/obo/GO_0044057 regulation of system process Any process that modulates the frequency, rate or extent of a muscle system process, a multicellular organismal process carried out by any of the organs or tissues in a muscle system. http://purl.obolibrary.org/obo/GO_0097427 microtubule bundle http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure An arrangement of closely apposed microtubules running parallel to each other. http://purl.obolibrary.org/obo/GO_0090304 nucleic acid metabolic process http://purl.obolibrary.org/obo/GO_0043170 macromolecule metabolic process Any cellular metabolic process involving nucleic acids. http://purl.obolibrary.org/obo/GO_0097432 hippocampal pyramidal neuron differentiation http://purl.obolibrary.org/obo/GO_0021895 cerebral cortex neuron differentiation The process in which a relatively unspecialized cell acquires specialized features of a hippocampal pyramidal neuron, a pyramidal cell of the hippocampus. http://purl.obolibrary.org/obo/GO_0090407 organophosphate biosynthetic process http://purl.obolibrary.org/obo/GO_0009058 biosynthetic process The chemical reactions and pathways resulting in the biosynthesis of deoxyribose phosphate, the phosphorylated sugar 2-deoxy-erythro-pentose. http://purl.obolibrary.org/obo/GO_0097447 dendritic tree http://purl.obolibrary.org/obo/GO_0043005 neuron projection The entire complement of dendrites for a neuron, consisting of each primary dendrite and all its branches. http://purl.obolibrary.org/obo/GO_0095500 acetylcholine receptor signaling pathway http://purl.obolibrary.org/obo/GO_0098926 postsynaptic signal transduction The series of molecular signals generated as a consequence of an acetylcholine receptor binding to one of its physiological ligands. http://purl.obolibrary.org/obo/GO_0097449 astrocyte projection http://purl.obolibrary.org/obo/GO_0097386 glial cell projection A prolongation or process extending from the soma of an astrocyte and wrapping around neurons. http://purl.obolibrary.org/obo/GO_0097014 ciliary plasm http://purl.obolibrary.org/obo/GO_0005737 cytoplasm All of the contents of a cilium, excluding the plasma membrane surrounding the cilium. http://purl.obolibrary.org/obo/GO_0097454 Schwann cell microvillus http://purl.obolibrary.org/obo/GO_0097386 glial cell projection Small finger-like extension of a Schwann cell that contacts the nodal membrane. http://purl.obolibrary.org/obo/GO_0097194 execution phase of apoptosis http://purl.obolibrary.org/obo/GO_0009987 cellular process A stage of the apoptotic process that starts with the controlled breakdown of the cell through the action of effector caspases or other effector molecules (e.g. cathepsins, calpains etc.). Key steps of the execution phase are rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died. http://purl.obolibrary.org/obo/GO_0097457 hippocampal mossy fiber http://purl.obolibrary.org/obo/GO_0030424 axon An axon of a hippocampal granule cell, including dentate gyrus granule cell and CA3 granule cell, characterized by expansions (mossy fiber expansions) giving the fibers a mossy appearance. These unmyelinated axons were first described by Ramon y Cajal. http://purl.obolibrary.org/obo/GO_0097435 supramolecular fiber organization http://purl.obolibrary.org/obo/GO_0016043 cellular component organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a supramolecular fiber, a polymer consisting of an indefinite number of protein or protein complex subunits that have polymerised to form a fiber-shaped structure. http://purl.obolibrary.org/obo/GO_0097473 retinal rod cell apoptotic process http://purl.obolibrary.org/obo/GO_0051402 neuron apoptotic process Any apoptotic process in a retinal rod cell, one of the two photoreceptor cell types of the vertebrate retina. http://purl.obolibrary.org/obo/GO_0098534 centriole assembly http://purl.obolibrary.org/obo/GO_0140694 membraneless organelle assembly A cellular process that results in the assembly of one or more centrioles. http://purl.obolibrary.org/obo/GO_0097474 retinal cone cell apoptotic process http://purl.obolibrary.org/obo/GO_0051402 neuron apoptotic process Any apoptotic process in a retinal cone cell, one of the two photoreceptor cell types of the vertebrate retina. http://purl.obolibrary.org/obo/GO_0098642 network-forming collagen trimer http://purl.obolibrary.org/obo/GO_0005581 collagen trimer A collagen trimer that forms networks. http://purl.obolibrary.org/obo/GO_0097475 motor neuron migration http://purl.obolibrary.org/obo/GO_0001764 neuron migration The orderly movement of a motor neuron from one site to another. A motor neuron is an efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes movement. http://purl.obolibrary.org/obo/GO_0098643 fibrillar collagen complex http://purl.obolibrary.org/obo/GO_0098644 complex of collagen trimers A supramolecular assembly of fibrillar collagen complexes in the form of a long fiber (fibril) with transverse striations (bands). http://purl.obolibrary.org/obo/GO_0097476 spinal cord motor neuron migration http://purl.obolibrary.org/obo/GO_0097475 motor neuron migration The orderly movement of a spinal cord motor neuron from one site to another. A spinal cord motor neuron is a motor neuron that passes from the spinal cord toward or to a muscle and conducts an impulse that causes movement. http://purl.obolibrary.org/obo/GO_0098645 complex of network-forming collagens http://purl.obolibrary.org/obo/GO_0098644 complex of collagen trimers A supramolecular complex that consists of collagen triple helices associated to form a network. http://purl.obolibrary.org/obo/GO_0098664 G protein-coupled serotonin receptor signaling pathway http://purl.obolibrary.org/obo/GO_0007186 G protein-coupled receptor signaling pathway The series of molecular signals generated as a consequence of a G protein-coupled serotonin receptor binding to one of its physiological ligands. http://purl.obolibrary.org/obo/GO_0097477 lateral motor column neuron migration http://purl.obolibrary.org/obo/GO_0097476 spinal cord motor neuron migration The orderly movement of a lateral motor column neuron from one site to another. A lateral motor column neuron is a motor neuron that is generated only on limb levels and send axons into the limb mesenchyme. http://purl.obolibrary.org/obo/GO_0098793 presynapse http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure The part of a synapse that is part of the presynaptic cell. http://purl.obolibrary.org/obo/GO_0098798 mitochondrial protein-containing complex http://purl.obolibrary.org/obo/GO_0032991 protein-containing complex A protein complex that is part of a mitochondrion. http://purl.obolibrary.org/obo/GO_0097499 protein localization to non-motile cilium http://purl.obolibrary.org/obo/GO_0061512 protein localization to cilium A process in which a protein is transported to, or maintained in, a location within a non-motile cilium. http://purl.obolibrary.org/obo/GO_0098802 plasma membrane signaling receptor complex http://purl.obolibrary.org/obo/GO_0098797 plasma membrane protein complex Any protein complex that is part of the plasma membrane and which functions as a signaling receptor. http://purl.obolibrary.org/obo/GO_0097511 dendritic cell dendrite http://purl.obolibrary.org/obo/GO_0120025 plasma membrane bounded cell projection A branched cellular projection (or cytoplasmic extension) that is extended from the surface of a dendritic immune cell, and which enables the cell to sample luminal pathogens and increase the surface area for antigen presentation to T cells. http://purl.obolibrary.org/obo/GO_0098858 actin-based cell projection http://purl.obolibrary.org/obo/GO_0120025 plasma membrane bounded cell projection A cell projection supported by an assembly of actin filaments, and which lacks microtubules. http://purl.obolibrary.org/obo/GO_0097512 cardiac myofibril http://purl.obolibrary.org/obo/GO_0030016 myofibril A cardiac myofibril is a myofibril specific to cardiac muscle cells. http://purl.obolibrary.org/obo/GO_0098862 cluster of actin-based cell projections http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure A cell part consisting of multiple, closely packed actin-based cell projections. http://purl.obolibrary.org/obo/GO_0097524 sperm plasma membrane http://purl.obolibrary.org/obo/GO_0005886 plasma membrane A plasma membrane that is part of a sperm cell. http://purl.obolibrary.org/obo/GO_0098876 vesicle-mediated transport to the plasma membrane http://purl.obolibrary.org/obo/GO_0051668 localization within membrane The directed movement of substances to the plasma membrane in transport vesicles that fuse with the plasma membrane by exocytosis. http://purl.obolibrary.org/obo/GO_0097534 lymphoid lineage cell migration http://purl.obolibrary.org/obo/GO_0016477 cell migration The orderly movement of a lymphoid lineage cell from one site to another. A lymphoid lineage cell, also called a lymphoid lineage restricted progenitor cell, is a progenitor cell restricted to the lymphoid lineage. http://purl.obolibrary.org/obo/GO_0098916 anterograde trans-synaptic signaling http://purl.obolibrary.org/obo/GO_0099537 trans-synaptic signaling Cell-cell signaling from pre to post-synapse, across the synaptic cleft. http://purl.obolibrary.org/obo/GO_0097536 thymus epithelium morphogenesis http://purl.obolibrary.org/obo/GO_0002009 morphogenesis of an epithelium The process in which the thymus epithelium is generated and organized. http://purl.obolibrary.org/obo/GO_0098930 axonal transport http://purl.obolibrary.org/obo/GO_0008088 axo-dendritic transport The directed movement of organelles or molecules along microtubules in axons. http://purl.obolibrary.org/obo/GO_0097540 axonemal central pair http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure Part of the axoneme consisting of the inner two microtubule doublets of the 9+2 axoneme occurring in most motile cilia. http://purl.obolibrary.org/obo/GO_0099080 supramolecular complex http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure A cellular component that consists of an indeterminate number of proteins or macromolecular complexes, organized into a regular, higher-order structure such as a polymer, sheet, network or a fiber. http://purl.obolibrary.org/obo/GO_0099094 ligand-gated monoatomic cation channel activity http://purl.obolibrary.org/obo/GO_0015276 ligand-gated monoatomic ion channel activity Enables the transmembrane transfer of an inorganic cation by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts. http://purl.obolibrary.org/obo/GO_0097545 axonemal doublet microtubule http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure A cellular anatomical entity that is part of an axoneme consisting of a doublet microtubule. http://purl.obolibrary.org/obo/GO_0099500 vesicle fusion to plasma membrane http://purl.obolibrary.org/obo/GO_0140029 exocytic process Fusion of the membrane of a vesicle with the plasma membrane, thereby releasing its contents into the extracellular space. http://purl.obolibrary.org/obo/GO_0097623 potassium ion export across plasma membrane http://purl.obolibrary.org/obo/GO_0140115 export across plasma membrane The directed movement of potassium ions from inside of a cell, across the plasma membrane and into the extracellular region. http://purl.obolibrary.org/obo/GO_0099589 serotonin receptor activity http://purl.obolibrary.org/obo/GO_0004888 transmembrane signaling receptor activity Combining with the biogenic amine serotonin and transmitting a signal across a membrane by activating some effector activity. Serotonin (5-hydroxytryptamine) is a neurotransmitter and hormone found in vertebrates and invertebrates. http://purl.obolibrary.org/obo/GO_0097628 distal tip cell migration http://purl.obolibrary.org/obo/GO_0016477 cell migration The orderly movement of a distal tip cell. http://purl.obolibrary.org/obo/GO_0097649 A axonemal microtubule http://purl.obolibrary.org/obo/GO_0005879 axonemal microtubule A complete microtubule with 13 protofilaments that fuses with an incomplete microtubule called B tubule (containing 10 protofilaments only) to form an axonemal outer doublet. Inner and outer dynein arms, as well as the radial spoke, are attached to the A tubule. http://purl.obolibrary.org/obo/GO_0099643 signal release from synapse http://purl.obolibrary.org/obo/GO_0023061 signal release Any signal release from a synapse. http://purl.obolibrary.org/obo/GO_0097650 B axonemal microtubule http://purl.obolibrary.org/obo/GO_0005879 axonemal microtubule An incomplete microtubule containing 10 protofilaments that fuses with a complete microtubule called A tubule (containing 13 protofilaments) to form an axonemal outer doublet. http://purl.obolibrary.org/obo/GO_1901135 carbohydrate derivative metabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process The chemical reactions and pathways involving carbohydrate derivative. http://purl.obolibrary.org/obo/GO_0097711 ciliary basal body-plasma membrane docking http://purl.obolibrary.org/obo/GO_0140056 organelle localization by membrane tethering The docking of a cytosolic centriole/basal body to the plasma membrane via the ciliary transition fibers. In some species this may happen via an intermediate step, by first docking to the ciliary vesicle via the ciliary transition fibers. The basal body-ciliary vesicle then relocates to the plasma membrane, followed by the ciliary vesicle fusing with the plasma membrane, effectively attaching the basal body to the plasma membrane. http://purl.obolibrary.org/obo/GO_1901136 carbohydrate derivative catabolic process http://purl.obolibrary.org/obo/GO_0009056 catabolic process The chemical reactions and pathways resulting in the breakdown of carbohydrate derivative. http://purl.obolibrary.org/obo/GO_0097719 neural tissue regeneration http://purl.obolibrary.org/obo/GO_0042246 tissue regeneration The regrowth of neural tissue following its loss or destruction. http://purl.obolibrary.org/obo/GO_1901137 carbohydrate derivative biosynthetic process http://purl.obolibrary.org/obo/GO_0009058 biosynthetic process The chemical reactions and pathways resulting in the formation of carbohydrate derivative. http://purl.obolibrary.org/obo/GO_0097742 de novo centriole assembly http://purl.obolibrary.org/obo/GO_0098534 centriole assembly Centriole assembly in which a centriole arises de novo, rather than by replication from an existing centriole. This process may occur via different mechanisms. Examples include the deuterosome pathway in multicilated epithelial animal cells and formation of centrioles during parthenogenesis in some insects. http://purl.obolibrary.org/obo/GO_1901375 acetate ester transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity Enables the transfer of an acetate ester from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0098520 excitatory neuromuscular junction http://purl.obolibrary.org/obo/GO_0060076 excitatory synapse The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a post-synaptic potential responsible for muscle contraction. http://purl.obolibrary.org/obo/GO_1901474 azole transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity Enables the directed movement of azoles, heterocyclic compound found in many biologically important substances, from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0098522 neuromuscular junction of skeletal muscle fiber http://purl.obolibrary.org/obo/GO_0098981 cholinergic synapse A neuromuscular junction in which the target muscle cell is a skeletal muscle fiber. http://purl.obolibrary.org/obo/GO_1901505 carbohydrate derivative transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity Enables the transfer of carbohydrate derivative from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0098523 neuromuscular junction of myotube http://purl.obolibrary.org/obo/GO_0031594 neuromuscular junction A neuromuscular junction in which the target muscle cell is a myotube. http://purl.obolibrary.org/obo/GO_1901606 alpha-amino acid catabolic process http://purl.obolibrary.org/obo/GO_0046395 carboxylic acid catabolic process The chemical reactions and pathways resulting in the breakdown of an alpha-amino acid. http://purl.obolibrary.org/obo/GO_0098524 neuromuscular junction of somatic muscle myotube http://purl.obolibrary.org/obo/GO_0098527 neuromuscular junction of somatic muscle A neuromuscular junction in which the target muscle cell is a somatic muscle myotube, such as an arthropod somatic muscle cell. http://purl.obolibrary.org/obo/GO_1901880 negative regulation of protein depolymerization http://purl.obolibrary.org/obo/GO_0043242 negative regulation of protein-containing complex disassembly Any process that stops, prevents or reduces the frequency, rate or extent of protein depolymerization. http://purl.obolibrary.org/obo/GO_0098525 excitatory neuromuscular junction of somatic myotube http://purl.obolibrary.org/obo/GO_0098524 neuromuscular junction of somatic muscle myotube A neuromuscular junction that functions in the excitation of somatic muscle myotubes, such as an arthropod somatic muscle cells. http://purl.obolibrary.org/obo/GO_1902001 fatty acid transmembrane transport http://purl.obolibrary.org/obo/GO_1905039 carboxylic acid transmembrane transport The process in which a fatty acid is transported across a membrane. http://purl.obolibrary.org/obo/GO_0098527 neuromuscular junction of somatic muscle http://purl.obolibrary.org/obo/GO_0031594 neuromuscular junction A neuromuscular junction in which the target muscle cell is a somatic muscle cell, such as those found in nematodes and arthropods. http://purl.obolibrary.org/obo/GO_1902850 microtubule cytoskeleton organization involved in mitosis http://purl.obolibrary.org/obo/GO_1903047 mitotic cell cycle process Any microtubule cytoskeleton organization that is involved in mitosis. http://purl.obolibrary.org/obo/GO_0098529 neuromuscular junction development, skeletal muscle fiber http://purl.obolibrary.org/obo/GO_0007528 neuromuscular junction development A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuromuscular junction that targets a skeletal muscle fiber. http://purl.obolibrary.org/obo/GO_1902875 regulation of embryonic pattern specification http://purl.obolibrary.org/obo/GO_0051239 regulation of multicellular organismal process Any process that modulates the frequency, rate or extent of embryonic pattern specification. http://purl.obolibrary.org/obo/GO_0098535 de novo centriole assembly involved in multi-ciliated epithelial cell differentiation http://purl.obolibrary.org/obo/GO_0097742 de novo centriole assembly Centriole assembly in which a centriole arises de novo by a process involving an electron-dense structure known as a deuterosome, rather than by duplication of an existing centriole, and occurring as part of multi-ciliated epithelial cell differentiation. http://purl.obolibrary.org/obo/GO_1902903 regulation of supramolecular fiber organization http://purl.obolibrary.org/obo/GO_0051128 regulation of cellular component organization Any process that modulates the frequency, rate or extent of supramolecular fiber organization. http://purl.obolibrary.org/obo/GO_0098536 deuterosome http://purl.obolibrary.org/obo/GO_0043232 intracellular membraneless organelle A spherical, electron dense, cytoplasmic structure that is involved in de novo assembly of centrioles. http://purl.obolibrary.org/obo/GO_1902904 negative regulation of supramolecular fiber organization http://purl.obolibrary.org/obo/GO_0051129 negative regulation of cellular component organization Any process that stops, prevents or reduces the frequency, rate or extent of fibril organization. http://purl.obolibrary.org/obo/GO_0098544 maintenance of protein complex location http://purl.obolibrary.org/obo/GO_0051235 maintenance of location Any process in which a protein complex is maintained in a location and prevented from moving elsewhere. These include sequestration, stabilization to prevent transport elsewhere and the active retrieval of protein complexes that move away. http://purl.obolibrary.org/obo/GO_1903429 regulation of cell maturation http://purl.obolibrary.org/obo/GO_0060284 regulation of cell development Any process that modulates the frequency, rate or extent of cell maturation. http://purl.obolibrary.org/obo/GO_0098545 maintenance of protein complex location in cytoplasm http://purl.obolibrary.org/obo/GO_0098544 maintenance of protein complex location Any process in which a protein complex is maintained in a specific location within the cytoplasm and is prevented from moving elsewhere. http://purl.obolibrary.org/obo/GO_0098594 mucin granule http://purl.obolibrary.org/obo/GO_0030141 secretory granule A secretory granule that contains mucin. http://purl.obolibrary.org/obo/GO_1903509 liposaccharide metabolic process http://purl.obolibrary.org/obo/GO_1901135 carbohydrate derivative metabolic process The chemical reactions and pathways involving liposaccharide. http://purl.obolibrary.org/obo/GO_0098631 cell adhesion mediator activity http://purl.obolibrary.org/obo/GO_0050839 cell adhesion molecule binding The binding by a cell-adhesion protein on a cell surface to an adhesion molecule on another cell surface or an external substrate, to mediate adhesion of the cell to the external substrate or to another cell. http://purl.obolibrary.org/obo/GO_1903522 regulation of blood circulation http://purl.obolibrary.org/obo/GO_0044057 regulation of system process Any process that modulates the frequency, rate or extent of blood circulation. http://purl.obolibrary.org/obo/GO_0098632 cell-cell adhesion mediator activity http://purl.obolibrary.org/obo/GO_0098631 cell adhesion mediator activity The binding by a cell-adhesion protein on the cell surface to an extracellular component of a different cell, to mediate adhesion of the cell to another cell. http://purl.obolibrary.org/obo/GO_1904115 axon cytoplasm http://purl.obolibrary.org/obo/GO_0120111 neuron projection cytoplasm Any cytoplasm that is part of a axon. http://purl.obolibrary.org/obo/GO_0098633 collagen fibril binding http://purl.obolibrary.org/obo/GO_0050840 extracellular matrix binding Binding to a collagen fibril. http://purl.obolibrary.org/obo/GO_1904659 D-glucose transmembrane transport http://purl.obolibrary.org/obo/GO_0008645 hexose transmembrane transport The process in which D-glucose is transported across a membrane. http://purl.obolibrary.org/obo/GO_0098635 protein complex involved in cell-cell adhesion http://purl.obolibrary.org/obo/GO_0098636 protein complex involved in cell adhesion Any protein complex that is capable of carrying out some part of the process of cell-cell adhesion. http://purl.obolibrary.org/obo/GO_1905030 voltage-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential http://purl.obolibrary.org/obo/GO_0005244 voltage-gated monoatomic ion channel activity Any voltage-gated ion channel activity that is involved in regulation of postsynaptic membrane potential. http://purl.obolibrary.org/obo/GO_0098641 cadherin binding involved in cell-cell adhesion http://purl.obolibrary.org/obo/GO_0098632 cell-cell adhesion mediator activity Any cadherin binding that occurs as part of the process of cell-cell adhesion. http://purl.obolibrary.org/obo/GO_1990542 mitochondrial transmembrane transport http://purl.obolibrary.org/obo/GO_0006839 mitochondrial transport The process in which a solute is transported from one side of a membrane to the other into, out of or within a mitochondrion. http://purl.obolibrary.org/obo/GO_0098644 complex of collagen trimers http://purl.obolibrary.org/obo/GO_0099080 supramolecular complex A complex of collagen trimers such as a fibril or collagen network. http://purl.obolibrary.org/obo/GO_2000178 negative regulation of neural precursor cell proliferation http://purl.obolibrary.org/obo/GO_0008285 negative regulation of cell population proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of neural precursor cell proliferation. http://purl.obolibrary.org/obo/GO_0098658 inorganic anion import across plasma membrane http://purl.obolibrary.org/obo/GO_0099587 inorganic ion import across plasma membrane The directed movement of inorganic anions from outside of a cell, across the plasma membrane and into the cytosol. http://purl.obolibrary.org/obo/GO_2000272 negative regulation of signaling receptor activity http://purl.obolibrary.org/obo/GO_0044092 negative regulation of molecular function Any process that stops, prevents or reduces the frequency, rate or extent of a signaling receptor activity. http://purl.obolibrary.org/obo/GO_0098659 inorganic cation import across plasma membrane http://purl.obolibrary.org/obo/GO_0099587 inorganic ion import across plasma membrane The directed movement of inorganic cations from outside of a cell, across the plasma membrane and into the cytosol. http://purl.obolibrary.org/obo/GO_2000647 negative regulation of stem cell proliferation http://purl.obolibrary.org/obo/GO_0072091 regulation of stem cell proliferation Any process that stops, prevents or reduces the frequency, rate or extent of stem cell proliferation. http://purl.obolibrary.org/obo/GO_0098665 serotonin receptor complex http://purl.obolibrary.org/obo/GO_0043235 receptor complex A protein complex that is capable of serotonin receptor activity. http://purl.obolibrary.org/obo/GO_2000831 regulation of steroid hormone secretion http://purl.obolibrary.org/obo/GO_0046883 regulation of hormone secretion Any process that modulates the frequency, rate or extent of steroid hormone secretion. http://purl.obolibrary.org/obo/GO_0098666 G protein-coupled serotonin receptor complex http://purl.obolibrary.org/obo/GO_0043235 receptor complex A protein complex that is capable of G protein-coupled serotonin receptor activity. http://purl.obolibrary.org/obo/GO_0045806 negative regulation of endocytosis http://purl.obolibrary.org/obo/GO_0051129 negative regulation of cellular component organization Any process that stops, prevents, or reduces the frequency, rate or extent of endocytosis. http://purl.obolibrary.org/obo/GO_0098703 calcium ion import across plasma membrane http://purl.obolibrary.org/obo/GO_1902656 calcium ion import into cytosol The directed movement of calcium ions from outside of a cell, across the plasma membrane and into the cytosol. http://purl.obolibrary.org/obo/GO_0098704 carbohydrate import across plasma membrane http://purl.obolibrary.org/obo/GO_0034219 carbohydrate transmembrane transport The directed movement of a carbohydrate from outside of a cell, across the plasma membrane and into the cytosol. http://purl.obolibrary.org/obo/GO_0045807 positive regulation of endocytosis http://purl.obolibrary.org/obo/GO_0051130 positive regulation of cellular component organization Any process that activates or increases the frequency, rate or extent of endocytosis. http://purl.obolibrary.org/obo/GO_0098708 D-glucose import across plasma membrane http://purl.obolibrary.org/obo/GO_0140271 hexose import across plasma membrane The directed movement of D-glucose from outside of a cell, across the plasma membrane and into the cytosol. http://purl.obolibrary.org/obo/GO_0045818 negative regulation of glycogen catabolic process http://purl.obolibrary.org/obo/GO_0009895 negative regulation of catabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen. http://purl.obolibrary.org/obo/GO_0098712 L-glutamate import across plasma membrane http://purl.obolibrary.org/obo/GO_0089718 amino acid import across plasma membrane The directed movement of L-glutamate from outside of a cell, across the plasma membrane and into the cytosol. http://purl.obolibrary.org/obo/GO_0045819 positive regulation of glycogen catabolic process http://purl.obolibrary.org/obo/GO_0009896 positive regulation of catabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen. http://purl.obolibrary.org/obo/GO_0098719 sodium ion import across plasma membrane http://purl.obolibrary.org/obo/GO_0098659 inorganic cation import across plasma membrane The directed movement of sodium ions from outside of a cell, across the plasma membrane and into the cytosol. http://purl.obolibrary.org/obo/GO_0045829 negative regulation of isotype switching http://purl.obolibrary.org/obo/GO_0045191 regulation of isotype switching Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching. http://purl.obolibrary.org/obo/GO_0098723 skeletal muscle myofibril http://purl.obolibrary.org/obo/GO_0030016 myofibril A myofibril of a skeletal muscle fiber. http://purl.obolibrary.org/obo/GO_0045830 positive regulation of isotype switching http://purl.obolibrary.org/obo/GO_0045191 regulation of isotype switching Any process that activates or increases the frequency, rate or extent of isotype switching. http://purl.obolibrary.org/obo/GO_0098739 import across plasma membrane http://purl.obolibrary.org/obo/GO_0098657 import into cell The directed movement of some substance from outside of a cell, across the plasma membrane and into the cytosol. http://purl.obolibrary.org/obo/GO_0045833 negative regulation of lipid metabolic process http://purl.obolibrary.org/obo/GO_0009892 negative regulation of metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving lipids. http://purl.obolibrary.org/obo/GO_0098749 cerebellar neuron development http://purl.obolibrary.org/obo/GO_0021954 central nervous system neuron development The process whose specific outcome is the progression of a cerebellar neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. http://purl.obolibrary.org/obo/GO_0045834 positive regulation of lipid metabolic process http://purl.obolibrary.org/obo/GO_0009893 positive regulation of metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving lipids. http://purl.obolibrary.org/obo/GO_0098804 non-motile cilium membrane http://purl.obolibrary.org/obo/GO_0060170 ciliary membrane The portion of the plasma membrane surrounding a non-motile cilium. http://purl.obolibrary.org/obo/GO_0045843 negative regulation of striated muscle tissue development http://purl.obolibrary.org/obo/GO_0048635 negative regulation of muscle organ development Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle development. http://purl.obolibrary.org/obo/GO_0098867 intramembranous bone growth http://purl.obolibrary.org/obo/GO_0098868 bone growth The increase in size or mass of an intramembranous bone that contributes to the shaping of the bone. http://purl.obolibrary.org/obo/GO_0045844 positive regulation of striated muscle tissue development http://purl.obolibrary.org/obo/GO_0048636 positive regulation of muscle organ development Any process that activates or increases the frequency, rate or extent of striated muscle development. http://purl.obolibrary.org/obo/GO_0098871 postsynaptic actin cytoskeleton http://purl.obolibrary.org/obo/GO_0099571 postsynaptic cytoskeleton The actin cytoskeleton that is part of a postsynapse. http://purl.obolibrary.org/obo/GO_0045849 negative regulation of nurse cell apoptotic process http://purl.obolibrary.org/obo/GO_2000242 negative regulation of reproductive process Any process that stops, prevents, or reduces the frequency, rate or extent of nurse cell apoptotic process. http://purl.obolibrary.org/obo/GO_0098877 neurotransmitter receptor transport to plasma membrane http://purl.obolibrary.org/obo/GO_0099637 neurotransmitter receptor transport The directed movement of neurotransmitter receptor to the plasma membrane in transport vesicles. http://purl.obolibrary.org/obo/GO_0045850 positive regulation of nurse cell apoptotic process http://purl.obolibrary.org/obo/GO_2000243 positive regulation of reproductive process Any process that activates or increases the frequency, rate or extent of nurse cell apoptotic process. http://purl.obolibrary.org/obo/GO_0098883 synapse pruning http://purl.obolibrary.org/obo/GO_0050808 synapse organization A cellular process that results in the controlled breakdown of synapse. After it starts the process is continuous until the synapse has disappeared. http://purl.obolibrary.org/obo/GO_0045900 negative regulation of translational elongation http://purl.obolibrary.org/obo/GO_0017148 negative regulation of translation Any process that stops, prevents, or reduces the frequency, rate or extent of translational elongation. http://purl.obolibrary.org/obo/GO_0045901 positive regulation of translational elongation http://purl.obolibrary.org/obo/GO_0045727 positive regulation of translation Any process that activates or increases the frequency, rate or extent of translational elongation. http://purl.obolibrary.org/obo/GO_0098901 regulation of cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_0098900 regulation of action potential Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a cardiac muscle cell. This typically occurs via modulation of the activity or expression of voltage-gated ion channels. http://purl.obolibrary.org/obo/GO_0045904 negative regulation of translational termination http://purl.obolibrary.org/obo/GO_0043242 negative regulation of protein-containing complex disassembly Any process that stops, prevents, or reduces the frequency, rate or extent of translational termination. http://purl.obolibrary.org/obo/GO_0098902 regulation of membrane depolarization during action potential http://purl.obolibrary.org/obo/GO_0003254 regulation of membrane depolarization Any process that modulates the rate, frequency or extent of membrane depolarization during an action potential. Membrane depolarization is the process in which membrane potential changes in the depolarizing direction from the resting potential. http://purl.obolibrary.org/obo/GO_0045905 positive regulation of translational termination http://purl.obolibrary.org/obo/GO_0045727 positive regulation of translation Any process that activates or increases the frequency, rate or extent of translational termination. http://purl.obolibrary.org/obo/GO_0098903 regulation of membrane repolarization during action potential http://purl.obolibrary.org/obo/GO_0060306 regulation of membrane repolarization Any process that modulates the rate, frequency or extent of membrane repolarization during an action potential. Membrane repolarization is the process in which membrane potential changes in the repolarizing direction, towards the resting potential. http://purl.obolibrary.org/obo/GO_0045928 negative regulation of juvenile hormone metabolic process http://purl.obolibrary.org/obo/GO_0045827 negative regulation of isoprenoid metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving juvenile hormone. http://purl.obolibrary.org/obo/GO_0098904 regulation of AV node cell action potential http://purl.obolibrary.org/obo/GO_0098901 regulation of cardiac muscle cell action potential Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in an atrioventricular node myocyte. This typically occurs via modulation of the activity or expression of voltage-gated ion channels. http://purl.obolibrary.org/obo/GO_0045931 positive regulation of mitotic cell cycle http://purl.obolibrary.org/obo/GO_0045787 positive regulation of cell cycle Any process that activates or increases the rate or extent of progression through the mitotic cell cycle. http://purl.obolibrary.org/obo/GO_0098905 regulation of bundle of His cell action potential http://purl.obolibrary.org/obo/GO_0098901 regulation of cardiac muscle cell action potential Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a cardiac muscle cell of the bundle of His. This typically occurs via modulation of the activity or expression of voltage-gated ion channels. http://purl.obolibrary.org/obo/GO_0045932 negative regulation of muscle contraction http://purl.obolibrary.org/obo/GO_0051241 negative regulation of multicellular organismal process Any process that stops, prevents, or reduces the frequency, rate or extent of muscle contraction. http://purl.obolibrary.org/obo/GO_0098906 regulation of Purkinje myocyte action potential http://purl.obolibrary.org/obo/GO_0098901 regulation of cardiac muscle cell action potential Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a Purkinje myocyte. This typically occurs via modulation of the activity or expression of voltage-gated ion channels. http://purl.obolibrary.org/obo/GO_0045933 positive regulation of muscle contraction http://purl.obolibrary.org/obo/GO_0051240 positive regulation of multicellular organismal process Any process that activates or increases the frequency, rate or extent of muscle contraction. http://purl.obolibrary.org/obo/GO_0098907 regulation of SA node cell action potential http://purl.obolibrary.org/obo/GO_0098901 regulation of cardiac muscle cell action potential Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in an SA node cardiac myocyte. This typically occurs via modulation of the activity or expression of voltage-gated ion channels. http://purl.obolibrary.org/obo/GO_0045952 regulation of juvenile hormone catabolic process http://purl.obolibrary.org/obo/GO_0050994 regulation of lipid catabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of juvenile hormone. http://purl.obolibrary.org/obo/GO_0098908 regulation of neuronal action potential http://purl.obolibrary.org/obo/GO_0098900 regulation of action potential Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a neuron. This typically occurs via modulation of the activity or expression of voltage-gated ion channels. http://purl.obolibrary.org/obo/GO_0045955 negative regulation of calcium ion-dependent exocytosis http://purl.obolibrary.org/obo/GO_0017158 regulation of calcium ion-dependent exocytosis Any process that stops, prevents, or reduces the frequency, rate or extent of calcium ion-dependent exocytosis. http://purl.obolibrary.org/obo/GO_0098909 regulation of cardiac muscle cell action potential involved in regulation of contraction http://purl.obolibrary.org/obo/GO_0098901 regulation of cardiac muscle cell action potential Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a cardiac muscle cell contributing to the regulation of its contraction. http://purl.obolibrary.org/obo/GO_0045956 positive regulation of calcium ion-dependent exocytosis http://purl.obolibrary.org/obo/GO_0017158 regulation of calcium ion-dependent exocytosis Any process that activates or increases the frequency, rate or extent of calcium ion-dependent exocytosis. http://purl.obolibrary.org/obo/GO_0098910 regulation of atrial cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_1903779 regulation of cardiac conduction Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in an atrial cardiac muscle cell contributing to the regulation of its contraction. This typically occurs via modulation of the activity or expression of voltage-gated ion channels. http://purl.obolibrary.org/obo/GO_0045963 negative regulation of dopamine metabolic process http://purl.obolibrary.org/obo/GO_0042053 regulation of dopamine metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving dopamine. http://purl.obolibrary.org/obo/GO_0098911 regulation of ventricular cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_0098901 regulation of cardiac muscle cell action potential Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a ventricular cardiac muscle cell contributing to the regulation of its contraction. This typically occurs via modulation of the activity or expression of voltage-gated ion channels. http://purl.obolibrary.org/obo/GO_0045964 positive regulation of dopamine metabolic process http://purl.obolibrary.org/obo/GO_0042053 regulation of dopamine metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving dopamine. http://purl.obolibrary.org/obo/GO_0098912 membrane depolarization during atrial cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_0086012 membrane depolarization during cardiac muscle cell action potential The process in which atrial cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential. http://purl.obolibrary.org/obo/GO_0045968 negative regulation of juvenile hormone biosynthetic process http://purl.obolibrary.org/obo/GO_0051055 negative regulation of lipid biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of juvenile hormone. http://purl.obolibrary.org/obo/GO_0098913 membrane depolarization during ventricular cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_0086012 membrane depolarization during cardiac muscle cell action potential The process in which ventricular cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential. http://purl.obolibrary.org/obo/GO_0045969 positive regulation of juvenile hormone biosynthetic process http://purl.obolibrary.org/obo/GO_0046889 positive regulation of lipid biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of juvenile hormone. http://purl.obolibrary.org/obo/GO_0098914 membrane repolarization during atrial cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_0099624 atrial cardiac muscle cell membrane repolarization The process in which ions are transported across a membrane such that the atrial cardiomyocyte membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential. http://purl.obolibrary.org/obo/GO_0045970 negative regulation of juvenile hormone catabolic process http://purl.obolibrary.org/obo/GO_0050995 negative regulation of lipid catabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of juvenile hormone. http://purl.obolibrary.org/obo/GO_0098915 membrane repolarization during ventricular cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_0099625 ventricular cardiac muscle cell membrane repolarization The process in which ions are transported across a membrane such that the ventricular cardiomyocyte membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential. http://purl.obolibrary.org/obo/GO_0045971 positive regulation of juvenile hormone catabolic process http://purl.obolibrary.org/obo/GO_0050996 positive regulation of lipid catabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of juvenile hormone. http://purl.obolibrary.org/obo/GO_0098917 retrograde trans-synaptic signaling http://purl.obolibrary.org/obo/GO_0099537 trans-synaptic signaling Cell-cell signaling from post to pre-synapse, across the synaptic cleft. http://purl.obolibrary.org/obo/GO_0045972 negative regulation of juvenile hormone secretion http://purl.obolibrary.org/obo/GO_0046888 negative regulation of hormone secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of juvenile hormone. http://purl.obolibrary.org/obo/GO_0098920 retrograde trans-synaptic signaling by lipid http://purl.obolibrary.org/obo/GO_0099541 trans-synaptic signaling by lipid Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by a lipid ligand. http://purl.obolibrary.org/obo/GO_0045973 positive regulation of juvenile hormone secretion http://purl.obolibrary.org/obo/GO_0046887 positive regulation of hormone secretion Any process that activates or increases the frequency, rate or extent of the regulated release of juvenile hormone. http://purl.obolibrary.org/obo/GO_0098923 retrograde trans-synaptic signaling by soluble gas http://purl.obolibrary.org/obo/GO_0099543 trans-synaptic signaling by soluble gas Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by an soluble gas ligand. http://purl.obolibrary.org/obo/GO_0045986 negative regulation of smooth muscle contraction http://purl.obolibrary.org/obo/GO_0006940 regulation of smooth muscle contraction Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle contraction. http://purl.obolibrary.org/obo/GO_0098924 retrograde trans-synaptic signaling by nitric oxide http://purl.obolibrary.org/obo/GO_0099548 trans-synaptic signaling by nitric oxide Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by nitric oxide. http://purl.obolibrary.org/obo/GO_0045987 positive regulation of smooth muscle contraction http://purl.obolibrary.org/obo/GO_0006940 regulation of smooth muscle contraction Any process that activates or increases the frequency, rate or extent of smooth muscle contraction. http://purl.obolibrary.org/obo/GO_0098925 retrograde trans-synaptic signaling by nitric oxide, modulating synaptic transmission http://purl.obolibrary.org/obo/GO_0099555 trans-synaptic signaling by nitric oxide, modulating synaptic transmission Modulation of synaptic transmission by cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by nitric oxide. http://purl.obolibrary.org/obo/GO_0045992 negative regulation of embryonic development http://purl.obolibrary.org/obo/GO_0051241 negative regulation of multicellular organismal process Any process that stops, prevents, or reduces the frequency, rate or extent of embryonic development. http://purl.obolibrary.org/obo/GO_0098926 postsynaptic signal transduction http://purl.obolibrary.org/obo/GO_0007165 signal transduction Signal transduction in which the initial step occurs in a postsynapse. http://purl.obolibrary.org/obo/GO_0045997 negative regulation of ecdysteroid biosynthetic process http://purl.obolibrary.org/obo/GO_0090032 negative regulation of steroid hormone biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ecdysteroids. http://purl.obolibrary.org/obo/GO_0098928 presynaptic signal transduction http://purl.obolibrary.org/obo/GO_0007165 signal transduction Signal transduction in which the initial step occurs in a presynapse. http://purl.obolibrary.org/obo/GO_0045998 positive regulation of ecdysteroid biosynthetic process http://purl.obolibrary.org/obo/GO_0090031 positive regulation of steroid hormone biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ecdysteroids. http://purl.obolibrary.org/obo/GO_0098934 retrograde dendritic transport http://purl.obolibrary.org/obo/GO_0098935 dendritic transport The directed movement of organelles or molecules along microtubules in a dendrite from the postsynapse towards the cell body. http://purl.obolibrary.org/obo/GO_0098935 dendritic transport http://purl.obolibrary.org/obo/GO_0008088 axo-dendritic transport The directed movement of organelles or molecules along microtubules in dendrites. http://purl.obolibrary.org/obo/GO_0045999 negative regulation of ecdysteroid secretion http://purl.obolibrary.org/obo/GO_2000832 negative regulation of steroid hormone secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of ecdysteroid. http://purl.obolibrary.org/obo/GO_0098937 anterograde dendritic transport http://purl.obolibrary.org/obo/GO_0098935 dendritic transport The directed movement of organelles or molecules along microtubules from the cell body toward the postsynapse in dendrites. http://purl.obolibrary.org/obo/GO_0098939 dendritic transport of mitochondrion http://purl.obolibrary.org/obo/GO_0098935 dendritic transport The directed movement of mitochondria along microtubules in nerve cell dendrites. http://purl.obolibrary.org/obo/GO_0046000 positive regulation of ecdysteroid secretion http://purl.obolibrary.org/obo/GO_2000833 positive regulation of steroid hormone secretion Any process that activates or increases the frequency, rate or extent of the regulated release of ecdysteroid. http://purl.obolibrary.org/obo/GO_0098940 anterograde trans-synaptic signaling by nitric oxide http://purl.obolibrary.org/obo/GO_0099548 trans-synaptic signaling by nitric oxide Cell-cell signaling from presynapse to postynapse, across the synaptic cleft, mediated by nitric oxide. http://purl.obolibrary.org/obo/GO_0046014 negative regulation of T cell homeostatic proliferation http://purl.obolibrary.org/obo/GO_0046013 regulation of T cell homeostatic proliferation Any process that stops, prevents or reduces the rate or extent of resting T cell proliferation. http://purl.obolibrary.org/obo/GO_0098957 anterograde axonal transport of mitochondrion http://purl.obolibrary.org/obo/GO_0019896 axonal transport of mitochondrion The directed movement of mitochondria along microtubules in axons away from the cell body and towards the presynapse. http://purl.obolibrary.org/obo/GO_0046032 ADP catabolic process http://purl.obolibrary.org/obo/GO_0009181 purine ribonucleoside diphosphate catabolic process The chemical reactions and pathways resulting in the breakdown of ADP, adenosine 5'-diphosphate. http://purl.obolibrary.org/obo/GO_0098958 retrograde axonal transport of mitochondrion http://purl.obolibrary.org/obo/GO_0019896 axonal transport of mitochondrion The directed movement of mitochondria along microtubules in axons towards the cell body and away from the presynapse. http://purl.obolibrary.org/obo/GO_0046210 nitric oxide catabolic process http://purl.obolibrary.org/obo/GO_0009056 catabolic process The chemical reactions and pathways resulting in the breakdown of nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water. http://purl.obolibrary.org/obo/GO_0098959 retrograde dendritic transport of mitochondrion http://purl.obolibrary.org/obo/GO_0098939 dendritic transport of mitochondrion The directed movement of mitochondria along microtubules in dendrites towards the cell body and away from the postsynapse. http://purl.obolibrary.org/obo/GO_0046324 regulation of D-glucose import across plasma membrane http://purl.obolibrary.org/obo/GO_0010827 regulation of D-glucose transmembrane transport Any process that modulates the frequency, rate or extent of the import of the hexose monosaccharide glucose into a cell. http://purl.obolibrary.org/obo/GO_0098960 postsynaptic neurotransmitter receptor activity http://purl.obolibrary.org/obo/GO_0030594 neurotransmitter receptor activity Neurotransmitter receptor activity occurring in the postsynaptic membrane during synaptic transmission. http://purl.obolibrary.org/obo/GO_0046325 negative regulation of D-glucose import across plasma membrane http://purl.obolibrary.org/obo/GO_0010829 negative regulation of D-glucose transmembrane transport Any process that stops, prevents, or reduces the frequency, rate or extent of the import of the hexose monosaccharide glucose into a cell. http://purl.obolibrary.org/obo/GO_0098961 dendritic transport of ribonucleoprotein complex http://purl.obolibrary.org/obo/GO_0098935 dendritic transport The directed movement of a ribonucleoprotein complex along microtubules in nerve cell dendrites. http://purl.obolibrary.org/obo/GO_0046326 positive regulation of D-glucose import across plasma membrane http://purl.obolibrary.org/obo/GO_0010828 positive regulation of D-glucose transmembrane transport Any process that activates or increases the frequency, rate or extent of the import of the hexose monosaccharide glucose into a cell. http://purl.obolibrary.org/obo/GO_0098967 exocytic insertion of neurotransmitter receptor to postsynaptic membrane http://purl.obolibrary.org/obo/GO_0099072 regulation of postsynaptic membrane neurotransmitter receptor levels The exocytic fusion of neurotransmitter receptor containing vesicles with the postsynaptic membrane resulting in the integration of NT receptors, enabling them to participate in neurotransmitter reception. This process includes tethering and docking steps that prepare vesicles for fusion. http://purl.obolibrary.org/obo/GO_0046541 saliva secretion http://purl.obolibrary.org/obo/GO_0032941 secretion by tissue The regulated release of saliva from the salivary glands. In man, the saliva is a turbid and slightly viscous fluid, generally of an alkaline reaction, and is secreted by the parotid, submaxillary, and sublingual glands. In the mouth the saliva is mixed with the secretion from the buccal glands. In man and many animals, saliva is an important digestive fluid on account of the presence of the peculiar enzyme, ptyalin. http://purl.obolibrary.org/obo/GO_0098969 neurotransmitter receptor transport to postsynaptic membrane http://purl.obolibrary.org/obo/GO_1903540 establishment of protein localization to postsynaptic membrane The directed movement of neurotransmitter receptor to the postsynaptic membrane in transport vesicles. http://purl.obolibrary.org/obo/GO_0046548 retinal rod cell development http://purl.obolibrary.org/obo/GO_0042462 eye photoreceptor cell development Development of a rod cell, one of the sensory cells in the eye that reacts to the presence of light. Rod cells contain the photopigment rhodopsin or porphyropsin and are responsible for vision in dim light. http://purl.obolibrary.org/obo/GO_0098971 anterograde dendritic transport of neurotransmitter receptor complex http://purl.obolibrary.org/obo/GO_0098937 anterograde dendritic transport The directed movement of a neurotransmitter receptor complex along microtubules in nerve cell dendrites towards the postsynapse. http://purl.obolibrary.org/obo/GO_0046549 retinal cone cell development http://purl.obolibrary.org/obo/GO_0042462 eye photoreceptor cell development Development of a cone cell, one of the sensory cells in the eye that reacts to the presence of light. Cone cells contain the photopigment iodopsin or cyanopsin and are responsible for photopic (daylight) vision. http://purl.obolibrary.org/obo/GO_0098972 anterograde dendritic transport of mitochondrion http://purl.obolibrary.org/obo/GO_0098939 dendritic transport of mitochondrion The directed movement of mitochondria along microtubules in dendrites towards the postsynapse and away from the cell body. http://purl.obolibrary.org/obo/GO_0046634 regulation of alpha-beta T cell activation http://purl.obolibrary.org/obo/GO_0050863 regulation of T cell activation Any process that modulates the frequency, rate or extent of alpha-beta T cell activation. http://purl.obolibrary.org/obo/GO_0098974 postsynaptic actin cytoskeleton organization http://purl.obolibrary.org/obo/GO_0099188 postsynaptic cytoskeleton organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins in the postsynaptic actin cytoskeleton. http://purl.obolibrary.org/obo/GO_0046635 positive regulation of alpha-beta T cell activation http://purl.obolibrary.org/obo/GO_0050870 positive regulation of T cell activation Any process that activates or increases the frequency, rate or extent of alpha-beta T cell activation. http://purl.obolibrary.org/obo/GO_0098975 postsynapse of neuromuscular junction http://purl.obolibrary.org/obo/GO_0098794 postsynapse The postsynapse of a neuromuscular junction. In vertebrate muscles this includes the motor end-plate, consisting of postjunctional folds of the sarcolemma. http://purl.obolibrary.org/obo/GO_0046636 negative regulation of alpha-beta T cell activation http://purl.obolibrary.org/obo/GO_0050868 negative regulation of T cell activation Any process that stops, prevents, or reduces the frequency, rate or extent of alpha-beta T cell activation. http://purl.obolibrary.org/obo/GO_0098976 excitatory chemical synaptic transmission http://purl.obolibrary.org/obo/GO_0007268 chemical synaptic transmission Synaptic transmission that results in an excitatory postsynaptic potential. http://purl.obolibrary.org/obo/GO_0046640 regulation of alpha-beta T cell proliferation http://purl.obolibrary.org/obo/GO_0042129 regulation of T cell proliferation Any process that modulates the frequency, rate or extent of alpha-beta T cell proliferation. http://purl.obolibrary.org/obo/GO_0098978 glutamatergic synapse http://purl.obolibrary.org/obo/GO_0045202 synapse A synapse that uses glutamate as a neurotransmitter. http://purl.obolibrary.org/obo/GO_0046641 positive regulation of alpha-beta T cell proliferation http://purl.obolibrary.org/obo/GO_0042102 positive regulation of T cell proliferation Any process that activates or increases the frequency, rate or extent of alpha-beta T cell proliferation. http://purl.obolibrary.org/obo/GO_0098981 cholinergic synapse http://purl.obolibrary.org/obo/GO_0045202 synapse A synapse that uses acetylcholine as a neurotransmitter. http://purl.obolibrary.org/obo/GO_0046642 negative regulation of alpha-beta T cell proliferation http://purl.obolibrary.org/obo/GO_0042130 negative regulation of T cell proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of alpha-beta T cell proliferation. http://purl.obolibrary.org/obo/GO_0098982 GABA-ergic synapse http://purl.obolibrary.org/obo/GO_0045202 synapse A synapse that uses GABA as a neurotransmitter. These synapses are typically inhibitory. http://purl.obolibrary.org/obo/GO_0046646 regulation of gamma-delta T cell proliferation http://purl.obolibrary.org/obo/GO_0046643 regulation of gamma-delta T cell activation Any process that modulates the frequency, rate or extent of gamma-delta T cell proliferation. http://purl.obolibrary.org/obo/GO_0098991 kainate selective glutamate receptor signaling pathway http://purl.obolibrary.org/obo/GO_0035235 ionotropic glutamate receptor signaling pathway The series of molecular signals initiated by glutamate binding to an kainate-selective glutamate receptor on the surface of the target cell, followed by the movement of ions through a channel in the receptor complex, ending with the regulation of a downstream cellular process, e.g. transcription. http://purl.obolibrary.org/obo/GO_0046647 negative regulation of gamma-delta T cell proliferation http://purl.obolibrary.org/obo/GO_0046644 negative regulation of gamma-delta T cell activation Any process that stops, prevents, or reduces the frequency, rate or extent of gamma-delta T cell proliferation. http://purl.obolibrary.org/obo/GO_0098992 neuronal dense core vesicle http://purl.obolibrary.org/obo/GO_0031045 dense core granule A dense core vesicle (granule) that is part of a neuron. These vesicles typically contain neuropeptides. They can be found in all parts of neurons, including the soma, dendrites, axonal swellings (varicosities) and synaptic terminals. http://purl.obolibrary.org/obo/GO_0046648 positive regulation of gamma-delta T cell proliferation http://purl.obolibrary.org/obo/GO_0046645 positive regulation of gamma-delta T cell activation Any process that activates or increases the frequency, rate or extent of gamma-delta T cell proliferation. http://purl.obolibrary.org/obo/GO_0046666 retinal cell programmed cell death http://purl.obolibrary.org/obo/GO_0010623 programmed cell death involved in cell development Programmed cell death that occurs in the developing retina. http://purl.obolibrary.org/obo/GO_0099011 neuronal dense core vesicle exocytosis http://purl.obolibrary.org/obo/GO_1990504 dense core granule exocytosis The secretion of molecules (e.g. neuropeptides, insulin-related peptides or neuromodulators such as serotonin and dopamine) contained within a neuronal dense core vesicle by fusion of the granule with the plasma membrane of a neuron in response to increased cytosolic calcium levels. http://purl.obolibrary.org/obo/GO_0046667 compound eye retinal cell programmed cell death http://purl.obolibrary.org/obo/GO_0046666 retinal cell programmed cell death Programmed cell death that occurs in the retina to remove excess cells between ommatidia, thus resulting in a hexagonal lattice, precise with respect to cell number and position surrounding each ommatidium. http://purl.obolibrary.org/obo/GO_0099012 neuronal dense core vesicle membrane http://purl.obolibrary.org/obo/GO_0032127 dense core granule membrane The lipid bilayer surrounding a neuronal dense core vesicle. http://purl.obolibrary.org/obo/GO_0046668 regulation of retinal cell programmed cell death http://purl.obolibrary.org/obo/GO_0043067 regulation of programmed cell death Any process that modulates the frequency, rate or extent of programmed cell death that occurs in the retina. http://purl.obolibrary.org/obo/GO_0099014 neuronal dense core vesicle organization http://purl.obolibrary.org/obo/GO_0061109 dense core granule organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuronal dense core vesicle. http://purl.obolibrary.org/obo/GO_0046669 regulation of compound eye retinal cell programmed cell death http://purl.obolibrary.org/obo/GO_0046668 regulation of retinal cell programmed cell death Any process that modulates the frequency, rate or extent of programmed cell death that occurs in the compound eye retina. http://purl.obolibrary.org/obo/GO_0099054 presynapse assembly http://purl.obolibrary.org/obo/GO_0099172 presynapse organization The aggregation, arrangement and bonding together of a set of components to form a presynapse. http://purl.obolibrary.org/obo/GO_0046670 positive regulation of retinal cell programmed cell death http://purl.obolibrary.org/obo/GO_0043068 positive regulation of programmed cell death Any process that activates or increases the frequency, rate or extent of programmed cell death that occurs in the retina. http://purl.obolibrary.org/obo/GO_0099068 postsynapse assembly http://purl.obolibrary.org/obo/GO_0022607 cellular component assembly The aggregation, arrangement and bonding together of a set of components to form a postsynapse. http://purl.obolibrary.org/obo/GO_0046671 negative regulation of retinal cell programmed cell death http://purl.obolibrary.org/obo/GO_0043069 negative regulation of programmed cell death Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death that occurs in the retina. http://purl.obolibrary.org/obo/GO_0099072 regulation of postsynaptic membrane neurotransmitter receptor levels http://purl.obolibrary.org/obo/GO_0065008 regulation of biological quality Any process that regulates the the local concentration of neurotransmitter receptor at the postsynaptic membrane. http://purl.obolibrary.org/obo/GO_0046672 positive regulation of compound eye retinal cell programmed cell death http://purl.obolibrary.org/obo/GO_0046670 positive regulation of retinal cell programmed cell death Any process that activates or increases the frequency, rate or extent of programmed cell death that occurs in the compound eye retina. http://purl.obolibrary.org/obo/GO_0099074 mitochondrion to lysosome vesicle-mediated transport http://purl.obolibrary.org/obo/GO_0099075 mitochondrion-derived vesicle mediated transport Vesicle-mediated transport of cargo from the mitochondrion to the lysosome, mediated by a mitochondrion-derived vesicle. http://purl.obolibrary.org/obo/GO_0099075 mitochondrion-derived vesicle mediated transport http://purl.obolibrary.org/obo/GO_0016192 vesicle-mediated transport Vesicle-mediated transport of cargo from the mitochondrion by a mitochondrion-derived vesicle. http://purl.obolibrary.org/obo/GO_0099081 supramolecular polymer http://purl.obolibrary.org/obo/GO_0099080 supramolecular complex A polymeric supramolecular structure. http://purl.obolibrary.org/obo/GO_0099082 retrograde trans-synaptic signaling by neuropeptide http://purl.obolibrary.org/obo/GO_0099540 trans-synaptic signaling by neuropeptide Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by a neuropeptide. http://purl.obolibrary.org/obo/GO_0099083 retrograde trans-synaptic signaling by neuropeptide, modulating synaptic transmission http://purl.obolibrary.org/obo/GO_0099551 trans-synaptic signaling by neuropeptide, modulating synaptic transmission Modulation of synaptic transmission by cell-cell signaling across the synaptic cleft from postsynapse to presynapse, mediated by a neuropeptide. http://purl.obolibrary.org/obo/GO_0099093 calcium export from the mitochondrion http://purl.obolibrary.org/obo/GO_0051209 release of sequestered calcium ion into cytosol A process in which a calcium ion (Ca2+) is transported out of the mitochondrial matrix, and into the cytosol. http://purl.obolibrary.org/obo/GO_0046673 negative regulation of compound eye retinal cell programmed cell death http://purl.obolibrary.org/obo/GO_0046671 negative regulation of retinal cell programmed cell death Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death that occurs in the compound eye retina. http://purl.obolibrary.org/obo/GO_0099096 vestibular calyx terminal http://purl.obolibrary.org/obo/GO_0043679 axon terminus The giant, cup-shaped axon terminal of a vestibular afferent neuron, serving as a post-synaptic contact to a type I hair cell. http://purl.obolibrary.org/obo/GO_0046676 negative regulation of insulin secretion http://purl.obolibrary.org/obo/GO_0050796 regulation of insulin secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of insulin. http://purl.obolibrary.org/obo/GO_0099112 microtubule polymerization based protein transport http://purl.obolibrary.org/obo/GO_0099118 microtubule-based protein transport The transport of a protein driven by polymerization of a microtubule to which it is attached. http://purl.obolibrary.org/obo/GO_0046697 decidualization http://purl.obolibrary.org/obo/GO_0009888 tissue development The cellular and vascular changes occurring in the endometrium of the pregnant uterus just after the onset of blastocyst implantation. This process involves the proliferation and differentiation of the fibroblast-like endometrial stromal cells into large, polyploid decidual cells that eventually form the maternal component of the placenta. http://purl.obolibrary.org/obo/GO_0099118 microtubule-based protein transport http://purl.obolibrary.org/obo/GO_0099111 microtubule-based transport A microtubule-based process that results in the transport of proteins. http://purl.obolibrary.org/obo/GO_0046716 muscle cell cellular homeostasis http://purl.obolibrary.org/obo/GO_0019725 cellular homeostasis The cellular homeostatic process that preserves a muscle cell in a stable functional or structural state. http://purl.obolibrary.org/obo/GO_0099123 somato-dendritic dopamine secretion http://purl.obolibrary.org/obo/GO_0014046 dopamine secretion The regulated release of dopamine from the somatodendritic compartment (cell body or dendrites) of a neuron. http://purl.obolibrary.org/obo/GO_0046826 negative regulation of protein export from nucleus http://purl.obolibrary.org/obo/GO_0046825 regulation of protein export from nucleus Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of proteins from the nucleus into the cytoplasm. http://purl.obolibrary.org/obo/GO_0099519 dense core granule cytoskeletal transport http://purl.obolibrary.org/obo/GO_1901950 dense core granule transport The directed movement of dense core granules along cytoskeletal fibers, such as microtubules or actin filaments. http://purl.obolibrary.org/obo/GO_0046828 regulation of RNA import into nucleus http://purl.obolibrary.org/obo/GO_0046822 regulation of nucleocytoplasmic transport Any process that modulates the frequency, rate or extent of movement of RNA from the cytoplasm to the nucleus. http://purl.obolibrary.org/obo/GO_0099523 presynaptic cytosol http://purl.obolibrary.org/obo/GO_0005829 cytosol The region of the cytosol consisting of all cytosol that is part of the presynapse. http://purl.obolibrary.org/obo/GO_0046829 negative regulation of RNA import into nucleus http://purl.obolibrary.org/obo/GO_0046823 negative regulation of nucleocytoplasmic transport Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of RNA from the cytoplasm into the nucleus. http://purl.obolibrary.org/obo/GO_0099524 postsynaptic cytosol http://purl.obolibrary.org/obo/GO_0005829 cytosol The region of the cytosol consisting of all cytosol that is part of the postsynapse. http://purl.obolibrary.org/obo/GO_0046830 positive regulation of RNA import into nucleus http://purl.obolibrary.org/obo/GO_0046824 positive regulation of nucleocytoplasmic transport Any process that activates or increases the frequency, rate or extent of movement of RNA from the cytoplasm into the nucleus. http://purl.obolibrary.org/obo/GO_0099525 presynaptic dense core vesicle exocytosis http://purl.obolibrary.org/obo/GO_0099011 neuronal dense core vesicle exocytosis The secretion of molecules (e.g. neuropeptides and neuromodulators such as serotonin and dopamine) contained within a membrane-bounced dense in response to increased presynaptic cytosolic calcium levels. http://purl.obolibrary.org/obo/GO_0046832 negative regulation of RNA export from nucleus http://purl.obolibrary.org/obo/GO_0046831 regulation of RNA export from nucleus Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of RNA from the nucleus into the cytoplasm. http://purl.obolibrary.org/obo/GO_0099530 G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential http://purl.obolibrary.org/obo/GO_0004930 G protein-coupled receptor activity A G protein-coupled receptor activity occurring in the postsynaptic membrane that is part of a GPCR signaling pathway that positively regulates ion channel activity in the postsynaptic membrane. http://purl.obolibrary.org/obo/GO_0046833 positive regulation of RNA export from nucleus http://purl.obolibrary.org/obo/GO_0046831 regulation of RNA export from nucleus Any process that activates or increases the frequency, rate or extent of directed movement of RNA from the nucleus into the cytoplasm. http://purl.obolibrary.org/obo/GO_0099533 positive regulation of presynaptic cytosolic calcium concentration http://purl.obolibrary.org/obo/GO_0007204 positive regulation of cytosolic calcium ion concentration Any process that increases the concentration of calcium ions in the presynaptic cytosol. http://purl.obolibrary.org/obo/GO_0046848 hydroxyapatite binding http://purl.obolibrary.org/obo/GO_0036094 small molecule binding Binding to hydroxyapatite, the calcium phosphate mineral of formula Ca10(PO4)6(OH)2 found both in rocks of nonorganic origin and as a component of bone and dentin. http://purl.obolibrary.org/obo/GO_0099536 synaptic signaling http://purl.obolibrary.org/obo/GO_0007267 cell-cell signaling Cell-cell signaling to, from or within a synapse. http://purl.obolibrary.org/obo/GO_0046864 isoprenoid transport http://purl.obolibrary.org/obo/GO_0006869 lipid transport The directed movement of isoprenoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Isoprenoids comprise a group of compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues. http://purl.obolibrary.org/obo/GO_0099537 trans-synaptic signaling http://purl.obolibrary.org/obo/GO_0099536 synaptic signaling Cell-cell signaling in either direction across the synaptic cleft. http://purl.obolibrary.org/obo/GO_0046866 tetraterpenoid transport http://purl.obolibrary.org/obo/GO_0046865 terpenoid transport The directed movement of tetraterpenoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Tetraterpenoids are terpenoids with eight isoprene units. http://purl.obolibrary.org/obo/GO_0099538 synaptic signaling via neuropeptide http://purl.obolibrary.org/obo/GO_0099536 synaptic signaling Cell-cell signaling to or from a synapse, mediated by a peptide. http://purl.obolibrary.org/obo/GO_0046867 carotenoid transport http://purl.obolibrary.org/obo/GO_0046866 tetraterpenoid transport The directed movement of carotenoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carotenoids are tetraterpenoid compounds in which two units of 4 isoprenoid residues joined head-to-tail are themselves joined tail-to-tail. http://purl.obolibrary.org/obo/GO_0099539 neuropeptide secretion from presynapse http://purl.obolibrary.org/obo/GO_0099525 presynaptic dense core vesicle exocytosis The secretion of neuropeptides contained within a dense core vesicle by fusion of the granule with the presynaptic membrane, stimulated by a rise in cytosolic calcium ion concentration. http://purl.obolibrary.org/obo/GO_0099540 trans-synaptic signaling by neuropeptide http://purl.obolibrary.org/obo/GO_0099538 synaptic signaling via neuropeptide Cell-cell signaling between presynapse and postsynapse mediated by a peptide ligand crossing the synaptic cleft. http://purl.obolibrary.org/obo/GO_0046877 regulation of saliva secretion http://purl.obolibrary.org/obo/GO_0044058 regulation of digestive system process Any process that modulates the frequency, rate or extent of the regulated release of saliva from a cell or a tissue. http://purl.obolibrary.org/obo/GO_0099541 trans-synaptic signaling by lipid http://purl.obolibrary.org/obo/GO_0099537 trans-synaptic signaling Cell-cell signaling from post to pre-synapse, across the synaptic cleft, mediated by a lipid. http://purl.obolibrary.org/obo/GO_0099543 trans-synaptic signaling by soluble gas http://purl.obolibrary.org/obo/GO_0099537 trans-synaptic signaling Cell-cell signaling between presynapse and postsynapse mediated by a soluble gas ligand crossing the synaptic cleft. http://purl.obolibrary.org/obo/GO_0046878 positive regulation of saliva secretion http://purl.obolibrary.org/obo/GO_0051047 positive regulation of secretion Any process that activates or increases the frequency, rate or extent of the regulated release of saliva. http://purl.obolibrary.org/obo/GO_0099546 protein catabolic process, modulating synaptic transmission http://purl.obolibrary.org/obo/GO_0140246 protein catabolic process at synapse Any protein degradation process, occurring at a presynapse, that regulates synaptic transmission. http://purl.obolibrary.org/obo/GO_0046931 pore complex assembly http://purl.obolibrary.org/obo/GO_0065003 protein-containing complex assembly The aggregation, arrangement and bonding together of a set of components to form a pore complex. A pore complex is a small opening in a membrane that allows the passage of liquids and/or gases. http://purl.obolibrary.org/obo/GO_0099547 regulation of translation at synapse, modulating synaptic transmission http://purl.obolibrary.org/obo/GO_0050804 modulation of chemical synaptic transmission Any process that modulates synaptic transmission by regulating translation occurring at the synapse. http://purl.obolibrary.org/obo/GO_0047496 vesicle transport along microtubule http://purl.obolibrary.org/obo/GO_0099518 vesicle cytoskeletal trafficking The directed movement of a vesicle along a microtubule, mediated by motor proteins. This process begins with the attachment of a vesicle to a microtubule, and ends when the vesicle reaches its final destination. http://purl.obolibrary.org/obo/GO_0099548 trans-synaptic signaling by nitric oxide http://purl.obolibrary.org/obo/GO_0099543 trans-synaptic signaling by soluble gas Cell-cell signaling between presynapse and postsynapse mediated by nitric oxide. http://purl.obolibrary.org/obo/GO_0048048 embryonic eye morphogenesis http://purl.obolibrary.org/obo/GO_0048592 eye morphogenesis The process occurring in the embryo by which the anatomical structures of the post-embryonic eye are generated and organized. http://purl.obolibrary.org/obo/GO_0099550 trans-synaptic signaling, modulating synaptic transmission http://purl.obolibrary.org/obo/GO_0099537 trans-synaptic signaling Cell-cell signaling between presynapse and postsynapse, across the synaptic cleft, that modulates the synaptic transmission properties of the synapse. http://purl.obolibrary.org/obo/GO_0048070 regulation of developmental pigmentation http://purl.obolibrary.org/obo/GO_0120305 regulation of pigmentation Any process that modulates the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism. http://purl.obolibrary.org/obo/GO_0099551 trans-synaptic signaling by neuropeptide, modulating synaptic transmission http://purl.obolibrary.org/obo/GO_0099550 trans-synaptic signaling, modulating synaptic transmission Cell-cell signaling between presynapse and postsynapse, via the vesicular release and reception of neuropeptide molecules, that modulates the synaptic transmission properties of the synapse. http://purl.obolibrary.org/obo/GO_0048086 negative regulation of developmental pigmentation http://purl.obolibrary.org/obo/GO_0048519 negative regulation of biological process Any process that decreases the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism. http://purl.obolibrary.org/obo/GO_0099552 trans-synaptic signaling by lipid, modulating synaptic transmission http://purl.obolibrary.org/obo/GO_0099550 trans-synaptic signaling, modulating synaptic transmission Cell-cell signaling between presynapse and postsynapse, via the release and reception of lipid molecules, that modulates the synaptic transmission properties of the synapse. http://purl.obolibrary.org/obo/GO_0048087 positive regulation of developmental pigmentation http://purl.obolibrary.org/obo/GO_0048518 positive regulation of biological process Any process that increases the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism. http://purl.obolibrary.org/obo/GO_0099554 trans-synaptic signaling by soluble gas, modulating synaptic transmission http://purl.obolibrary.org/obo/GO_0099550 trans-synaptic signaling, modulating synaptic transmission Cell-cell signaling between presynapse and postsynapse, via the release and reception of gaseous molecules, that modulates the synaptic transmission properties of the synapse. http://purl.obolibrary.org/obo/GO_0099555 trans-synaptic signaling by nitric oxide, modulating synaptic transmission http://purl.obolibrary.org/obo/GO_0099554 trans-synaptic signaling by soluble gas, modulating synaptic transmission Cell-cell signaling between presynapse and postsynapse, via the release and reception of nitric oxide molecules, that modulates the synaptic transmission properties of the synapse. http://purl.obolibrary.org/obo/GO_0048132 female germ-line stem cell asymmetric division http://purl.obolibrary.org/obo/GO_0098728 germline stem cell asymmetric division The self-renewing division of a germline stem cell in the female gonad, to produce a daughter stem cell and a daughter germ cell, which will divide to form the female gametes. http://purl.obolibrary.org/obo/GO_0099571 postsynaptic cytoskeleton http://purl.obolibrary.org/obo/GO_0005856 cytoskeleton The portion of the cytoskeleton contained within the postsynapse. http://purl.obolibrary.org/obo/GO_0048133 male germ-line stem cell asymmetric division http://purl.obolibrary.org/obo/GO_0098728 germline stem cell asymmetric division The self-renewing division of a germline stem cell in the male gonad, to produce a daughter stem cell and a daughter germ cell, which will divide to form the male gametes. http://purl.obolibrary.org/obo/GO_0099574 regulation of protein catabolic process at synapse, modulating synaptic transmission http://purl.obolibrary.org/obo/GO_0050804 modulation of chemical synaptic transmission Any process that modulates synaptic transmission by regulating protein degradation at the synapse. http://purl.obolibrary.org/obo/GO_0048137 spermatocyte division http://purl.obolibrary.org/obo/GO_0051301 cell division The meiotic divisions undergone by the primary and secondary spermatocytes to produce haploid spermatids. http://purl.obolibrary.org/obo/GO_0099575 regulation of protein catabolic process at presynapse, modulating synaptic transmission http://purl.obolibrary.org/obo/GO_0099171 presynaptic modulation of chemical synaptic transmission Any process that modulates synaptic transmission by regulating a catabolic process occurring at a presynapse. http://purl.obolibrary.org/obo/GO_0048144 fibroblast proliferation http://purl.obolibrary.org/obo/GO_0008283 cell population proliferation The multiplication or reproduction of fibroblast cells, resulting in the expansion of the fibroblast population. http://purl.obolibrary.org/obo/GO_0099576 regulation of protein catabolic process at postsynapse, modulating synaptic transmission http://purl.obolibrary.org/obo/GO_0099170 postsynaptic modulation of chemical synaptic transmission Any process that modulates synaptic transmission by regulating a catabolic process occurring at a postsynapse. http://purl.obolibrary.org/obo/GO_0048145 regulation of fibroblast proliferation http://purl.obolibrary.org/obo/GO_0042127 regulation of cell population proliferation Any process that modulates the frequency, rate or extent of multiplication or reproduction of fibroblast cells. http://purl.obolibrary.org/obo/GO_0099577 regulation of translation at presynapse, modulating synaptic transmission http://purl.obolibrary.org/obo/GO_0140244 regulation of translation at presynapse Any process that modulates synaptic transmission by regulating translation occurring at the presynapse. http://purl.obolibrary.org/obo/GO_0048146 positive regulation of fibroblast proliferation http://purl.obolibrary.org/obo/GO_0008284 positive regulation of cell population proliferation Any process that activates or increases the frequency, rate or extent of multiplication or reproduction of fibroblast cells. http://purl.obolibrary.org/obo/GO_0099578 regulation of translation at postsynapse, modulating synaptic transmission http://purl.obolibrary.org/obo/GO_0099170 postsynaptic modulation of chemical synaptic transmission Any process that modulates synaptic transmission by regulating translation occurring at the postsynapse. http://purl.obolibrary.org/obo/GO_0048147 negative regulation of fibroblast proliferation http://purl.obolibrary.org/obo/GO_0008285 negative regulation of cell population proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of multiplication or reproduction of fibroblast cells. http://purl.obolibrary.org/obo/GO_0099585 release of sequestered calcium ion into presynaptic cytosol http://purl.obolibrary.org/obo/GO_0051209 release of sequestered calcium ion into cytosol The process in which calcium ions sequestered in the endoplasmic reticulum, Golgi apparatus or mitochondria are released into the presynaptic cytosol. http://purl.obolibrary.org/obo/GO_0048240 sperm capacitation http://purl.obolibrary.org/obo/GO_0048469 cell maturation A process required for sperm to reach fertilization competence. Sperm undergo an incompletely understood series of morphological and molecular maturational processes, termed capacitation, involving, among other processes, protein tyrosine phosphorylation and increased intracellular calcium. http://purl.obolibrary.org/obo/GO_0099586 release of sequestered calcium ion into postsynaptic cytosol http://purl.obolibrary.org/obo/GO_0051209 release of sequestered calcium ion into cytosol The process in which calcium ions sequestered in the endoplasmic reticulum, Golgi apparatus or mitochondria are released into the postsynaptic cytosol. http://purl.obolibrary.org/obo/GO_0048241 epinephrine transport http://purl.obolibrary.org/obo/GO_0051937 catecholamine transport The directed movement of epinephrine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0099587 inorganic ion import across plasma membrane http://purl.obolibrary.org/obo/GO_0098739 import across plasma membrane The directed movement of inorganic ions from outside of a cell, across the plasma membrane and into the cytosol. http://purl.obolibrary.org/obo/GO_0048245 eosinophil chemotaxis http://purl.obolibrary.org/obo/GO_0071621 granulocyte chemotaxis The movement of an eosinophil in response to an external stimulus. http://purl.obolibrary.org/obo/GO_0099588 positive regulation of postsynaptic cytosolic calcium concentration http://purl.obolibrary.org/obo/GO_0007204 positive regulation of cytosolic calcium ion concentration Any process that increases the concentration of calcium ions in the postsynaptic cytosol. http://purl.obolibrary.org/obo/GO_0048250 iron import into the mitochondrion http://purl.obolibrary.org/obo/GO_0034755 iron ion transmembrane transport The process in which iron is transported from the cytosol into the mitochondrial matrix. http://purl.obolibrary.org/obo/GO_0099601 regulation of neurotransmitter receptor activity http://purl.obolibrary.org/obo/GO_0010469 regulation of signaling receptor activity Any process that modulates the frequency, rate or extent of neurotransmitter receptor activity. Modulation may be via an effect on ligand affinity, or effector function such as ion selectivity or pore opening/closing in ionotropic receptors. http://purl.obolibrary.org/obo/GO_0048251 elastic fiber assembly http://purl.obolibrary.org/obo/GO_0085029 extracellular matrix assembly Assembly of the extracellular matrix fibers that enables the matrix to recoil after transient stretching. http://purl.obolibrary.org/obo/GO_0099622 cardiac muscle cell membrane repolarization http://purl.obolibrary.org/obo/GO_0086009 membrane repolarization The process in which ions are transported across the plasma membrane of a cardiac muscle cell such that the membrane potential changes in the repolarizing direction, toward the steady state potential. For example, the repolarization during an action potential is from a positive membrane potential towards a negative resting potential. http://purl.obolibrary.org/obo/GO_0048280 vesicle fusion with Golgi apparatus http://purl.obolibrary.org/obo/GO_0007030 Golgi organization The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane around the Golgi. http://purl.obolibrary.org/obo/GO_0099635 voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels http://purl.obolibrary.org/obo/GO_0005245 voltage-gated calcium channel activity Positive regulation of presynaptic cytosolic calcium ion concentrations via the directed movement of calcium ions across the plasma-membrane into the cytosol via the action of voltage-gated calcium ion channels. This is the first step in synaptic transmission. http://purl.obolibrary.org/obo/GO_0048286 lung alveolus development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the alveolus over time, from its formation to the mature structure. The alveolus is a sac for holding air in the lungs; formed by the terminal dilation of air passageways. http://purl.obolibrary.org/obo/GO_0099637 neurotransmitter receptor transport http://purl.obolibrary.org/obo/GO_0031503 protein-containing complex localization The directed movement of neurotransmitter receptors. http://purl.obolibrary.org/obo/GO_0048288 nuclear membrane fusion involved in karyogamy http://purl.obolibrary.org/obo/GO_0000740 nuclear membrane fusion The joining of 2 or more lipid bilayer membranes that surround the nucleus during the creation of a single nucleus from multiple nuclei. http://purl.obolibrary.org/obo/GO_0099640 axo-dendritic protein transport http://purl.obolibrary.org/obo/GO_0098840 protein transport along microtubule The directed movement of proteins along microtubules in neuron projections. http://purl.obolibrary.org/obo/GO_0099641 anterograde axonal protein transport http://purl.obolibrary.org/obo/GO_1905383 protein localization to presynapse The directed movement of proteins along microtubules from the cell body toward the cell periphery in nerve cell axons. http://purl.obolibrary.org/obo/GO_0048293 regulation of isotype switching to IgE isotypes http://purl.obolibrary.org/obo/GO_0045191 regulation of isotype switching Any process that modulates the frequency, rate or extent of isotype switching to IgE isotypes. http://purl.obolibrary.org/obo/GO_0099642 retrograde axonal protein transport http://purl.obolibrary.org/obo/GO_0099640 axo-dendritic protein transport The directed movement of proteins along microtubules from the cell periphery toward the cell body in nerve cell axons. http://purl.obolibrary.org/obo/GO_0048294 negative regulation of isotype switching to IgE isotypes http://purl.obolibrary.org/obo/GO_0048293 regulation of isotype switching to IgE isotypes Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching to IgE isotypes. http://purl.obolibrary.org/obo/GO_0099703 induction of synaptic vesicle exocytosis by positive regulation of presynaptic cytosolic calcium ion concentration http://purl.obolibrary.org/obo/GO_2000302 positive regulation of synaptic vesicle exocytosis The induction of synaptic vesicle release by any process that leads to a rise in intracellular calcium ion concentration at the presynapse. This is the first step in synaptic transmission. http://purl.obolibrary.org/obo/GO_0048295 positive regulation of isotype switching to IgE isotypes http://purl.obolibrary.org/obo/GO_0048293 regulation of isotype switching to IgE isotypes Any process that activates or increases the frequency, rate or extent of isotype switching to IgE isotypes. http://purl.obolibrary.org/obo/GO_0101010 pulmonary blood vessel remodeling http://purl.obolibrary.org/obo/GO_0001974 blood vessel remodeling The reorganization or renovation of existing pulmonary blood vessels. http://purl.obolibrary.org/obo/GO_0101023 vascular endothelial cell proliferation http://purl.obolibrary.org/obo/GO_0001935 endothelial cell proliferation The multiplication or reproduction of blood vessel endothelial cells, resulting in the expansion of a cell population. http://purl.obolibrary.org/obo/GO_0048306 calcium-dependent protein binding http://purl.obolibrary.org/obo/GO_0005515 protein binding Binding to a protein or protein complex in the presence of calcium. http://purl.obolibrary.org/obo/GO_0101024 mitotic nuclear membrane organization http://purl.obolibrary.org/obo/GO_0071763 nuclear membrane organization A mitotic cell cycle process which results in the assembly, arrangement, or disassembly of the nuclear inner or outer membrane during mitosis. http://purl.obolibrary.org/obo/GO_0048313 Golgi inheritance http://purl.obolibrary.org/obo/GO_0048308 organelle inheritance The partitioning of Golgi apparatus between daughter cells at cell division. http://purl.obolibrary.org/obo/GO_0101025 nuclear membrane biogenesis http://purl.obolibrary.org/obo/GO_0044091 membrane biogenesis The process in which a nuclear membrane is synthesized, aggregates, and bonds together. http://purl.obolibrary.org/obo/GO_0048318 axial mesoderm development http://purl.obolibrary.org/obo/GO_0007498 mesoderm development The process whose specific outcome is the progression of the axial mesoderm over time, from its formation to the mature structure. The axial mesoderm includes the prechordal mesoderm and the chordamesoderm. It gives rise to the prechordal plate and to the notochord. http://purl.obolibrary.org/obo/GO_1900015 regulation of cytokine production involved in inflammatory response http://purl.obolibrary.org/obo/GO_0001817 regulation of cytokine production Any process that modulates the frequency, rate or extent of cytokine production involved in inflammatory response. http://purl.obolibrary.org/obo/GO_0048319 axial mesoderm morphogenesis http://purl.obolibrary.org/obo/GO_0048332 mesoderm morphogenesis The process in which the anatomical structures of the axial mesoderm are generated and organized. http://purl.obolibrary.org/obo/GO_1900016 negative regulation of cytokine production involved in inflammatory response http://purl.obolibrary.org/obo/GO_1900015 regulation of cytokine production involved in inflammatory response Any process that stops, prevents or reduces the frequency, rate or extent of cytokine production involved in inflammatory response. http://purl.obolibrary.org/obo/GO_0048320 axial mesoderm formation http://purl.obolibrary.org/obo/GO_0001707 mesoderm formation The process that gives rise to the axial mesoderm. This process pertains to the initial formation of the structure from unspecified parts. http://purl.obolibrary.org/obo/GO_1900017 positive regulation of cytokine production involved in inflammatory response http://purl.obolibrary.org/obo/GO_1900015 regulation of cytokine production involved in inflammatory response Any process that activates or increases the frequency, rate or extent of cytokine production involved in inflammatory response. http://purl.obolibrary.org/obo/GO_0048339 paraxial mesoderm development http://purl.obolibrary.org/obo/GO_0060485 mesenchyme development The process whose specific outcome is the progression of the paraxial mesoderm over time, from its formation to the mature structure. The paraxial mesoderm is the mesoderm located bilaterally adjacent to the notochord and neural tube. http://purl.obolibrary.org/obo/GO_1900073 regulation of neuromuscular synaptic transmission http://purl.obolibrary.org/obo/GO_0050804 modulation of chemical synaptic transmission Any process that modulates the frequency, rate or extent of neuromuscular synaptic transmission. http://purl.obolibrary.org/obo/GO_0048340 paraxial mesoderm morphogenesis http://purl.obolibrary.org/obo/GO_0072132 mesenchyme morphogenesis The process in which the anatomical structures of the paraxial mesoderm are generated and organized. http://purl.obolibrary.org/obo/GO_1900074 negative regulation of neuromuscular synaptic transmission http://purl.obolibrary.org/obo/GO_1900073 regulation of neuromuscular synaptic transmission Any process that stops, prevents or reduces the frequency, rate or extent of neuromuscular synaptic transmission. http://purl.obolibrary.org/obo/GO_1900075 positive regulation of neuromuscular synaptic transmission http://purl.obolibrary.org/obo/GO_1900073 regulation of neuromuscular synaptic transmission Any process that activates or increases the frequency, rate or extent of neuromuscular synaptic transmission. http://purl.obolibrary.org/obo/GO_1900098 regulation of plasma cell differentiation http://purl.obolibrary.org/obo/GO_0050776 regulation of immune response Any process that modulates the frequency, rate or extent of plasma cell differentiation. http://purl.obolibrary.org/obo/GO_1900099 negative regulation of plasma cell differentiation http://purl.obolibrary.org/obo/GO_1900098 regulation of plasma cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of plasma cell differentiation. http://purl.obolibrary.org/obo/GO_0048341 paraxial mesoderm formation http://purl.obolibrary.org/obo/GO_0001707 mesoderm formation The process that gives rise to the paraxial mesoderm. This process pertains to the initial formation of the structure from unspecified parts. http://purl.obolibrary.org/obo/GO_1900100 positive regulation of plasma cell differentiation http://purl.obolibrary.org/obo/GO_1900098 regulation of plasma cell differentiation Any process that activates or increases the frequency, rate or extent of plasma cell differentiation. http://purl.obolibrary.org/obo/GO_0048369 lateral mesoderm morphogenesis http://purl.obolibrary.org/obo/GO_0072132 mesenchyme morphogenesis The process in which the anatomical structures of the lateral mesoderm are generated and organized. http://purl.obolibrary.org/obo/GO_1900115 extracellular regulation of signal transduction http://purl.obolibrary.org/obo/GO_0009966 regulation of signal transduction Any regulation of signal transduction that takes place in the extracellular region. http://purl.obolibrary.org/obo/GO_0048370 lateral mesoderm formation http://purl.obolibrary.org/obo/GO_0001707 mesoderm formation The process that gives rise to the lateral mesoderm. This process pertains to the initial formation of the structure from unspecified parts. http://purl.obolibrary.org/obo/GO_1900117 regulation of execution phase of apoptosis http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of execution phase of apoptosis. http://purl.obolibrary.org/obo/GO_0048389 intermediate mesoderm development http://purl.obolibrary.org/obo/GO_0007498 mesoderm development The process whose specific outcome is the progression of the intermediate mesoderm over time, from its formation to the mature structure. The intermediate mesoderm is located between the lateral mesoderm and the paraxial mesoderm. It develops into the kidney and gonads. http://purl.obolibrary.org/obo/GO_1900118 negative regulation of execution phase of apoptosis http://purl.obolibrary.org/obo/GO_1900117 regulation of execution phase of apoptosis Any process that stops, prevents or reduces the frequency, rate or extent of execution phase of apoptosis. http://purl.obolibrary.org/obo/GO_0048390 intermediate mesoderm morphogenesis http://purl.obolibrary.org/obo/GO_0048332 mesoderm morphogenesis The process in which the anatomical structures of the intermediate mesoderm are generated and organized. http://purl.obolibrary.org/obo/GO_1900119 positive regulation of execution phase of apoptosis http://purl.obolibrary.org/obo/GO_0043065 positive regulation of apoptotic process Any process that activates or increases the frequency, rate or extent of execution phase of apoptosis. http://purl.obolibrary.org/obo/GO_0048391 intermediate mesoderm formation http://purl.obolibrary.org/obo/GO_0001707 mesoderm formation The process that gives rise to the intermediate mesoderm. This process pertains to the initial formation of the structure from unspecified parts. http://purl.obolibrary.org/obo/GO_1900125 regulation of hyaluronan biosynthetic process http://purl.obolibrary.org/obo/GO_0032885 regulation of polysaccharide biosynthetic process Any process that modulates the frequency, rate or extent of hyaluronan biosynthetic process. http://purl.obolibrary.org/obo/GO_0048484 enteric nervous system development http://purl.obolibrary.org/obo/GO_0048731 system development The process whose specific outcome is the progression of the enteric nervous system over time, from its formation to the mature structure. The enteric nervous system is composed of two ganglionated neural plexuses in the gut wall which form one of the three major divisions of the autonomic nervous system. The enteric nervous system innervates the gastrointestinal tract, the pancreas, and the gallbladder. It contains sensory neurons, interneurons, and motor neurons. Thus the circuitry can autonomously sense the tension and the chemical environment in the gut and regulate blood vessel tone, motility, secretions, and fluid transport. The system is itself governed by the central nervous system and receives both parasympathetic and sympathetic innervation. http://purl.obolibrary.org/obo/GO_1900126 negative regulation of hyaluronan biosynthetic process http://purl.obolibrary.org/obo/GO_0045912 negative regulation of carbohydrate metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of hyaluronan biosynthetic process. http://purl.obolibrary.org/obo/GO_0048485 sympathetic nervous system development http://purl.obolibrary.org/obo/GO_0048731 system development The process whose specific outcome is the progression of the sympathetic nervous system over time, from its formation to the mature structure. The sympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system (the other being the parasympathetic nervous system). The sympathetic preganglionic neurons have their cell bodies in the thoracic and lumbar regions of the spinal cord and connect to the paravertebral chain of sympathetic ganglia. Innervate heart and blood vessels, sweat glands, viscera and the adrenal medulla. Most sympathetic neurons, but not all, use noradrenaline as a post-ganglionic neurotransmitter. http://purl.obolibrary.org/obo/GO_1900127 positive regulation of hyaluronan biosynthetic process http://purl.obolibrary.org/obo/GO_0045913 positive regulation of carbohydrate metabolic process Any process that activates or increases the frequency, rate or extent of hyaluronan biosynthetic process. http://purl.obolibrary.org/obo/GO_0048535 lymph node development http://purl.obolibrary.org/obo/GO_0048534 hematopoietic or lymphoid organ development The process whose specific outcome is the progression of lymph nodes over time, from their formation to the mature structure. A lymph node is a round, oval, or bean shaped structure localized in clusters along the lymphatic vessels, with a distinct internal structure including specialized vasculature and B- and T-zones for the activation of lymphocytes. http://purl.obolibrary.org/obo/GO_1900131 negative regulation of lipid binding http://purl.obolibrary.org/obo/GO_0051100 negative regulation of binding Any process that stops, prevents or reduces the frequency, rate or extent of lipid binding. http://purl.obolibrary.org/obo/GO_0048536 spleen development http://purl.obolibrary.org/obo/GO_0048534 hematopoietic or lymphoid organ development The process whose specific outcome is the progression of the spleen over time, from its formation to the mature structure. The spleen is a large vascular lymphatic organ composed of white and red pulp, involved both in hemopoietic and immune system functions. http://purl.obolibrary.org/obo/GO_1900133 regulation of renin secretion into blood stream http://purl.obolibrary.org/obo/GO_0098801 regulation of renal system process Any process that modulates the frequency, rate or extent of renin secretion into blood stream. http://purl.obolibrary.org/obo/GO_0048537 mucosa-associated lymphoid tissue development http://purl.obolibrary.org/obo/GO_0048534 hematopoietic or lymphoid organ development The process whose specific outcome is the progression of mucosal-associated lymphoid tissue over time, from its formation to the mature structure. Mucosal-associated lymphoid tissue is typically found as nodules associated with mucosal epithelia with distinct internal structures including B- and T-zones for the activation of lymphocytes. http://purl.obolibrary.org/obo/GO_1900134 negative regulation of renin secretion into blood stream http://purl.obolibrary.org/obo/GO_1900133 regulation of renin secretion into blood stream Any process that stops, prevents or reduces the frequency, rate or extent of renin secretion into blood stream. http://purl.obolibrary.org/obo/GO_0048538 thymus development http://purl.obolibrary.org/obo/GO_0048534 hematopoietic or lymphoid organ development The process whose specific outcome is the progression of the thymus over time, from its formation to the mature structure. The thymus is a symmetric bi-lobed organ involved primarily in the differentiation of immature to mature T cells, with unique vascular, nervous, epithelial, and lymphoid cell components. http://purl.obolibrary.org/obo/GO_1900135 positive regulation of renin secretion into blood stream http://purl.obolibrary.org/obo/GO_1900133 regulation of renin secretion into blood stream Any process that activates or increases the frequency, rate or extent of renin secretion into blood stream. http://purl.obolibrary.org/obo/GO_0048539 bone marrow development http://purl.obolibrary.org/obo/GO_0048534 hematopoietic or lymphoid organ development The process whose specific outcome is the progression of the bone marrow over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_1900141 regulation of oligodendrocyte apoptotic process http://purl.obolibrary.org/obo/GO_0034350 regulation of glial cell apoptotic process Any process that modulates the frequency, rate or extent of oligodendrocyte apoptotic process. http://purl.obolibrary.org/obo/GO_0048541 Peyer's patch development http://purl.obolibrary.org/obo/GO_0048537 mucosa-associated lymphoid tissue development The process whose specific outcome is the progression of Peyer's patches over time, from their formation to the mature structure. Peyer's patches are typically found as nodules associated with gut epithelium with distinct internal structures including B- and T-zones for the activation of lymphocytes. http://purl.obolibrary.org/obo/GO_1900142 negative regulation of oligodendrocyte apoptotic process http://purl.obolibrary.org/obo/GO_1900141 regulation of oligodendrocyte apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of oligodendrocyte apoptotic process. http://purl.obolibrary.org/obo/GO_0048601 oocyte morphogenesis http://purl.obolibrary.org/obo/GO_0003006 developmental process involved in reproduction The process in which the structures of an oocyte are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of an oocyte. http://purl.obolibrary.org/obo/GO_1900143 positive regulation of oligodendrocyte apoptotic process http://purl.obolibrary.org/obo/GO_1900141 regulation of oligodendrocyte apoptotic process Any process that activates or increases the frequency, rate or extent of oligodendrocyte apoptotic process. http://purl.obolibrary.org/obo/GO_0048627 myoblast development http://purl.obolibrary.org/obo/GO_0048468 cell development The process whose specific outcome is the progression of the myoblast over time, from its formation to the mature structure. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. http://purl.obolibrary.org/obo/GO_1900147 regulation of Schwann cell migration http://purl.obolibrary.org/obo/GO_1903975 regulation of glial cell migration Any process that modulates the frequency, rate or extent of Schwann cell migration. http://purl.obolibrary.org/obo/GO_0048630 skeletal muscle tissue growth http://purl.obolibrary.org/obo/GO_0048589 developmental growth The increase in size or mass of a skeletal muscle. This may be due to a change in the fiber number or size. http://purl.obolibrary.org/obo/GO_0048631 regulation of skeletal muscle tissue growth http://purl.obolibrary.org/obo/GO_0048638 regulation of developmental growth Any process that modulates the frequency, rate or extent of skeletal muscle growth. http://purl.obolibrary.org/obo/GO_1900148 negative regulation of Schwann cell migration http://purl.obolibrary.org/obo/GO_1900147 regulation of Schwann cell migration Any process that stops, prevents or reduces the frequency, rate or extent of Schwann cell migration. http://purl.obolibrary.org/obo/GO_1900149 positive regulation of Schwann cell migration http://purl.obolibrary.org/obo/GO_1903977 positive regulation of glial cell migration Any process that activates or increases the frequency, rate or extent of Schwann cell migration. http://purl.obolibrary.org/obo/GO_0048632 negative regulation of skeletal muscle tissue growth http://purl.obolibrary.org/obo/GO_0048640 negative regulation of developmental growth Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle growth. http://purl.obolibrary.org/obo/GO_0048633 positive regulation of skeletal muscle tissue growth http://purl.obolibrary.org/obo/GO_0048643 positive regulation of skeletal muscle tissue development Any process that activates, maintains or increases the rate of skeletal muscle growth. http://purl.obolibrary.org/obo/GO_1900158 negative regulation of bone mineralization involved in bone maturation http://purl.obolibrary.org/obo/GO_0030502 negative regulation of bone mineralization Any process that stops, prevents or reduces the frequency, rate or extent of bone mineralization involved in bone maturation. http://purl.obolibrary.org/obo/GO_0048644 muscle organ morphogenesis http://purl.obolibrary.org/obo/GO_0009887 animal organ morphogenesis The process in which the anatomical structures of muscle are generated and organized. http://purl.obolibrary.org/obo/GO_1900159 positive regulation of bone mineralization involved in bone maturation http://purl.obolibrary.org/obo/GO_0030501 positive regulation of bone mineralization Any process that activates or increases the frequency, rate or extent of bone mineralization involved in bone maturation. http://purl.obolibrary.org/obo/GO_0048659 smooth muscle cell proliferation http://purl.obolibrary.org/obo/GO_0033002 muscle cell proliferation The multiplication or reproduction of smooth muscle cells, resulting in the expansion of a cell population. http://purl.obolibrary.org/obo/GO_1900160 plastid chromosome packaging http://purl.obolibrary.org/obo/GO_0051276 chromosome organization A process in which plastidial DNA and associated proteins organize into a compact, orderly structure. http://purl.obolibrary.org/obo/GO_0048660 regulation of smooth muscle cell proliferation http://purl.obolibrary.org/obo/GO_0042127 regulation of cell population proliferation Any process that modulates the frequency, rate or extent of smooth muscle cell proliferation. http://purl.obolibrary.org/obo/GO_1900193 regulation of oocyte maturation http://purl.obolibrary.org/obo/GO_2000241 regulation of reproductive process Any process that modulates the frequency, rate or extent of oocyte maturation. http://purl.obolibrary.org/obo/GO_0048661 positive regulation of smooth muscle cell proliferation http://purl.obolibrary.org/obo/GO_0008284 positive regulation of cell population proliferation Any process that activates or increases the rate or extent of smooth muscle cell proliferation. http://purl.obolibrary.org/obo/GO_1900194 negative regulation of oocyte maturation http://purl.obolibrary.org/obo/GO_2000242 negative regulation of reproductive process Any process that stops, prevents or reduces the frequency, rate or extent of oocyte maturation. http://purl.obolibrary.org/obo/GO_1900195 positive regulation of oocyte maturation http://purl.obolibrary.org/obo/GO_2000243 positive regulation of reproductive process Any process that activates or increases the frequency, rate or extent of oocyte maturation. http://purl.obolibrary.org/obo/GO_0048662 negative regulation of smooth muscle cell proliferation http://purl.obolibrary.org/obo/GO_0008285 negative regulation of cell population proliferation Any process that stops, prevents or reduces the rate or extent of smooth muscle cell proliferation. http://purl.obolibrary.org/obo/GO_1900200 mesenchymal cell apoptotic process involved in metanephros development http://purl.obolibrary.org/obo/GO_0097152 mesenchymal cell apoptotic process Any mesenchymal cell apoptotic process that is involved in metanephros development. http://purl.obolibrary.org/obo/GO_1900206 regulation of pronephric nephron tubule development http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of pronephric nephron tubule development. http://purl.obolibrary.org/obo/GO_0048710 regulation of astrocyte differentiation http://purl.obolibrary.org/obo/GO_0045685 regulation of glial cell differentiation Any process that modulates the frequency, rate or extent of astrocyte differentiation. http://purl.obolibrary.org/obo/GO_1900207 negative regulation of pronephric nephron tubule development http://purl.obolibrary.org/obo/GO_1900206 regulation of pronephric nephron tubule development Any process that stops, prevents or reduces the frequency, rate or extent of pronephric nephron tubule development. http://purl.obolibrary.org/obo/GO_0048711 positive regulation of astrocyte differentiation http://purl.obolibrary.org/obo/GO_0045687 positive regulation of glial cell differentiation Any process that activates or increases the frequency, rate or extent of astrocyte differentiation. http://purl.obolibrary.org/obo/GO_1900247 regulation of cytoplasmic translational elongation http://purl.obolibrary.org/obo/GO_0006448 regulation of translational elongation Any process that modulates the frequency, rate or extent of cytoplasmic translational elongation. http://purl.obolibrary.org/obo/GO_0048712 negative regulation of astrocyte differentiation http://purl.obolibrary.org/obo/GO_0045686 negative regulation of glial cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of astrocyte differentiation. http://purl.obolibrary.org/obo/GO_1900248 negative regulation of cytoplasmic translational elongation http://purl.obolibrary.org/obo/GO_2000766 negative regulation of cytoplasmic translation Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic translational elongation. http://purl.obolibrary.org/obo/GO_0048713 regulation of oligodendrocyte differentiation http://purl.obolibrary.org/obo/GO_0045685 regulation of glial cell differentiation Any process that modulates the frequency, rate or extent of oligodendrocyte differentiation. http://purl.obolibrary.org/obo/GO_1900249 positive regulation of cytoplasmic translational elongation http://purl.obolibrary.org/obo/GO_1900247 regulation of cytoplasmic translational elongation Any process that activates or increases the frequency, rate or extent of cytoplasmic translational elongation. http://purl.obolibrary.org/obo/GO_0048714 positive regulation of oligodendrocyte differentiation http://purl.obolibrary.org/obo/GO_0045687 positive regulation of glial cell differentiation Any process that activates or increases the frequency, rate or extent of oligodendrocyte differentiation. http://purl.obolibrary.org/obo/GO_1900366 negative regulation of defense response to insect http://purl.obolibrary.org/obo/GO_0032102 negative regulation of response to external stimulus Any process that stops, prevents or reduces the frequency, rate or extent of defense response to insect. http://purl.obolibrary.org/obo/GO_0048715 negative regulation of oligodendrocyte differentiation http://purl.obolibrary.org/obo/GO_0045686 negative regulation of glial cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of oligodendrocyte differentiation. http://purl.obolibrary.org/obo/GO_1900367 positive regulation of defense response to insect http://purl.obolibrary.org/obo/GO_2000068 regulation of defense response to insect Any process that activates or increases the frequency, rate or extent of defense response to insect. http://purl.obolibrary.org/obo/GO_0048741 skeletal muscle fiber development http://purl.obolibrary.org/obo/GO_0014904 myotube cell development The process whose specific outcome is the progression of the skeletal muscle fiber over time, from its formation to the mature structure. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast. http://purl.obolibrary.org/obo/GO_1900407 regulation of cellular response to oxidative stress http://purl.obolibrary.org/obo/GO_1902882 regulation of response to oxidative stress Any process that modulates the frequency, rate or extent of cellular response to oxidative stress. http://purl.obolibrary.org/obo/GO_0048742 regulation of skeletal muscle fiber development http://purl.obolibrary.org/obo/GO_0060284 regulation of cell development Any process that modulates the frequency, rate or extent of skeletal muscle fiber development. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast. http://purl.obolibrary.org/obo/GO_1900408 negative regulation of cellular response to oxidative stress http://purl.obolibrary.org/obo/GO_1902883 negative regulation of response to oxidative stress Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to oxidative stress. http://purl.obolibrary.org/obo/GO_0048743 positive regulation of skeletal muscle fiber development http://purl.obolibrary.org/obo/GO_0051155 positive regulation of striated muscle cell differentiation Any process that activates, maintains or increases the rate of skeletal muscle fiber development. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast. http://purl.obolibrary.org/obo/GO_1900409 positive regulation of cellular response to oxidative stress http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the frequency, rate or extent of cellular response to oxidative stress. http://purl.obolibrary.org/obo/GO_0048744 negative regulation of skeletal muscle fiber development http://purl.obolibrary.org/obo/GO_0051154 negative regulation of striated muscle cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle fiber development. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast. http://purl.obolibrary.org/obo/GO_1900419 regulation of alcohol catabolic process http://purl.obolibrary.org/obo/GO_0009894 regulation of catabolic process Any process that modulates the frequency, rate or extent of alcohol catabolic process within a cell. http://purl.obolibrary.org/obo/GO_0048745 smooth muscle tissue development http://purl.obolibrary.org/obo/GO_0060537 muscle tissue development The process whose specific outcome is the progression of smooth muscle over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_1900420 negative regulation of alcohol catabolic process http://purl.obolibrary.org/obo/GO_0009895 negative regulation of catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of alcohol catabolic process within a cell. http://purl.obolibrary.org/obo/GO_0048752 semicircular canal morphogenesis http://purl.obolibrary.org/obo/GO_0048598 embryonic morphogenesis The process in which the anatomical structures of the semicircular canals are generated and organized. http://purl.obolibrary.org/obo/GO_1900421 positive regulation of alcohol catabolic process http://purl.obolibrary.org/obo/GO_0009896 positive regulation of catabolic process Any process that activates or increases the frequency, rate or extent of alcohol catabolic process within a cell. http://purl.obolibrary.org/obo/GO_0048755 branching morphogenesis of a nerve http://purl.obolibrary.org/obo/GO_0001763 morphogenesis of a branching structure The process in which the anatomical structures of branches in a nerve are generated and organized. This term refers to an anatomical structure (nerve) not a cell (neuron). http://purl.obolibrary.org/obo/GO_1900449 regulation of glutamate receptor signaling pathway http://purl.obolibrary.org/obo/GO_0009966 regulation of signal transduction Any process that modulates the frequency, rate or extent of glutamate receptor signaling pathway. http://purl.obolibrary.org/obo/GO_0048772 leucophore differentiation http://purl.obolibrary.org/obo/GO_0050931 pigment cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a leucophore cell. Leucophores are pigment cells derived from the neural crest. They contain uric acid or other purine crystals, deposited in stacks called leucosomes. This gives them a white appearance. http://purl.obolibrary.org/obo/GO_1900450 negative regulation of glutamate receptor signaling pathway http://purl.obolibrary.org/obo/GO_1900449 regulation of glutamate receptor signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of glutamate receptor signaling pathway. http://purl.obolibrary.org/obo/GO_0048773 erythrophore differentiation http://purl.obolibrary.org/obo/GO_0050931 pigment cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of an erythrophore cell. Erythrophores are pigment cells derived from the neural crest. They contain pteridine and/or carotenoid pigments in structures called pterinosomes or erythrosomes. This gives them an orange to red appearance. http://purl.obolibrary.org/obo/GO_1900451 positive regulation of glutamate receptor signaling pathway http://purl.obolibrary.org/obo/GO_1900449 regulation of glutamate receptor signaling pathway Any process that activates or increases the frequency, rate or extent of glutamate receptor signaling pathway. http://purl.obolibrary.org/obo/GO_0048774 cyanophore differentiation http://purl.obolibrary.org/obo/GO_0050931 pigment cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a cyanophore cell. Cyanophores are pigment cells derived from the neural crest. They contain a blue pigment of unknown chemical composition. The pigment is stored in fibrous organelles termed cyanosomes. http://purl.obolibrary.org/obo/GO_1900825 regulation of membrane depolarization during cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_0098902 regulation of membrane depolarization during action potential Any process that modulates the frequency, rate or extent of membrane depolarization during a cardiac muscle cell action potential. http://purl.obolibrary.org/obo/GO_0048775 regulation of leucophore differentiation http://purl.obolibrary.org/obo/GO_0050932 regulation of pigment cell differentiation Any process that modulates the frequency, rate or extent of leucophore differentiation. http://purl.obolibrary.org/obo/GO_1900826 negative regulation of membrane depolarization during cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_1900825 regulation of membrane depolarization during cardiac muscle cell action potential Any process that stops, prevents or reduces the frequency, rate or extent of membrane depolarization during a cardiac muscle cell action potential. http://purl.obolibrary.org/obo/GO_0048776 negative regulation of leucophore differentiation http://purl.obolibrary.org/obo/GO_0050941 negative regulation of pigment cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of leucophore differentiation. http://purl.obolibrary.org/obo/GO_1900827 positive regulation of membrane depolarization during cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_1900825 regulation of membrane depolarization during cardiac muscle cell action potential Any process that activates or increases the frequency, rate or extent of membrane depolarization during a cardiac muscle cell action potential. http://purl.obolibrary.org/obo/GO_0048777 positive regulation of leucophore differentiation http://purl.obolibrary.org/obo/GO_0050942 positive regulation of pigment cell differentiation Any process that activates or increases the frequency, rate or extent of leucophore differentiation. http://purl.obolibrary.org/obo/GO_1900923 regulation of glycine import across plasma membrane http://purl.obolibrary.org/obo/GO_0010958 regulation of amino acid import across plasma membrane Any process that modulates the frequency, rate or extent of glycine import into a cell. http://purl.obolibrary.org/obo/GO_0048778 regulation of erythrophore differentiation http://purl.obolibrary.org/obo/GO_0050932 regulation of pigment cell differentiation Any process that modulates the frequency, rate or extent of erythrophore differentiation. http://purl.obolibrary.org/obo/GO_1900924 negative regulation of glycine import across plasma membrane http://purl.obolibrary.org/obo/GO_1900923 regulation of glycine import across plasma membrane Any process that stops, prevents or reduces the frequency, rate or extent of glycine import into a cell. http://purl.obolibrary.org/obo/GO_0048779 negative regulation of erythrophore differentiation http://purl.obolibrary.org/obo/GO_0050941 negative regulation of pigment cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of erythrophore differentiation. http://purl.obolibrary.org/obo/GO_1900925 positive regulation of glycine import across plasma membrane http://purl.obolibrary.org/obo/GO_1900923 regulation of glycine import across plasma membrane Any process that activates or increases the frequency, rate or extent of glycine import. http://purl.obolibrary.org/obo/GO_0048780 positive regulation of erythrophore differentiation http://purl.obolibrary.org/obo/GO_0050942 positive regulation of pigment cell differentiation Any process that activates or increases the frequency, rate or extent of erythrophore differentiation. http://purl.obolibrary.org/obo/GO_1901017 negative regulation of potassium ion transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0032413 negative regulation of ion transmembrane transporter activity Any process that stops, prevents or reduces the frequency, rate or extent of potassium ion transmembrane transporter activity. http://purl.obolibrary.org/obo/GO_0048781 regulation of cyanophore differentiation http://purl.obolibrary.org/obo/GO_0050932 regulation of pigment cell differentiation Any process that modulates the frequency, rate or extent of cyanophore differentiation. http://purl.obolibrary.org/obo/GO_1901031 regulation of response to reactive oxygen species http://purl.obolibrary.org/obo/GO_1902882 regulation of response to oxidative stress Any process that modulates the frequency, rate or extent of response to reactive oxygen species. http://purl.obolibrary.org/obo/GO_0048782 negative regulation of cyanophore differentiation http://purl.obolibrary.org/obo/GO_0050941 negative regulation of pigment cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of cyanophore differentiation. http://purl.obolibrary.org/obo/GO_1901032 negative regulation of response to reactive oxygen species http://purl.obolibrary.org/obo/GO_1902883 negative regulation of response to oxidative stress Any process that stops, prevents or reduces the frequency, rate or extent of response to reactive oxygen species. http://purl.obolibrary.org/obo/GO_0048783 positive regulation of cyanophore differentiation http://purl.obolibrary.org/obo/GO_0050942 positive regulation of pigment cell differentiation Any process that activates or increases the frequency, rate or extent of cyanophore differentiation. http://purl.obolibrary.org/obo/GO_1901033 positive regulation of response to reactive oxygen species http://purl.obolibrary.org/obo/GO_1902884 positive regulation of response to oxidative stress Any process that activates or increases the frequency, rate or extent of response to reactive oxygen species. http://purl.obolibrary.org/obo/GO_0048791 calcium ion-regulated exocytosis of neurotransmitter http://purl.obolibrary.org/obo/GO_0017156 calcium-ion regulated exocytosis The release of a neurotransmitter into the synaptic cleft by exocytosis of synaptic vesicles, where the release step is dependent on a rise in cytosolic calcium ion levels. http://purl.obolibrary.org/obo/GO_1901143 insulin catabolic process http://purl.obolibrary.org/obo/GO_1901142 insulin metabolic process The chemical reactions and pathways resulting in the breakdown of insulin. http://purl.obolibrary.org/obo/GO_0048808 male genitalia morphogenesis http://purl.obolibrary.org/obo/GO_0090598 male anatomical structure morphogenesis The process in which the anatomical structures of male genitalia are generated and organized. http://purl.obolibrary.org/obo/GO_0048813 dendrite morphogenesis http://purl.obolibrary.org/obo/GO_0048812 neuron projection morphogenesis The process in which the anatomical structures of a dendrite are generated and organized. http://purl.obolibrary.org/obo/GO_1901148 gene expression involved in extracellular matrix organization http://purl.obolibrary.org/obo/GO_0010467 gene expression Any gene expression that is involved in extracellular matrix organization. Gene expression includes both transcription to produce an RNA transcript, and the translation of that mRNA into protein. Protein maturation is included in gene expression when required to form an active form of a product from an inactive precursor form. http://purl.obolibrary.org/obo/GO_0048814 regulation of dendrite morphogenesis http://purl.obolibrary.org/obo/GO_0022603 regulation of anatomical structure morphogenesis Any process that modulates the frequency, rate or extent of dendrite morphogenesis. http://purl.obolibrary.org/obo/GO_1901163 regulation of trophoblast cell migration http://purl.obolibrary.org/obo/GO_0030334 regulation of cell migration Any process that modulates the frequency, rate or extent of trophoblast cell migration. http://purl.obolibrary.org/obo/GO_0048817 negative regulation of hair follicle maturation http://purl.obolibrary.org/obo/GO_0051799 negative regulation of hair follicle development Any process that stops, prevents, or reduces the frequency, rate or extent of hair follicle maturation. http://purl.obolibrary.org/obo/GO_1901164 negative regulation of trophoblast cell migration http://purl.obolibrary.org/obo/GO_2000242 negative regulation of reproductive process Any process that stops, prevents or reduces the frequency, rate or extent of trophoblast cell migration. http://purl.obolibrary.org/obo/GO_0048818 positive regulation of hair follicle maturation http://purl.obolibrary.org/obo/GO_0051798 positive regulation of hair follicle development Any process that activates or increases the frequency, rate or extent of hair follicle maturation. http://purl.obolibrary.org/obo/GO_0048819 regulation of hair follicle maturation http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of hair follicle maturation. http://purl.obolibrary.org/obo/GO_1901165 positive regulation of trophoblast cell migration http://purl.obolibrary.org/obo/GO_2000243 positive regulation of reproductive process Any process that activates or increases the frequency, rate or extent of trophoblast cell migration. http://purl.obolibrary.org/obo/GO_0048847 adenohypophysis formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process that gives rise to adenohypophysis. This process pertains to the initial formation of a structure from unspecified parts. The adenohypophysis is the anterior part of the pituitary. It secretes a variety of hormones and its function is regulated by the hypothalamus. http://purl.obolibrary.org/obo/GO_0048848 neurohypophysis morphogenesis http://purl.obolibrary.org/obo/GO_0022612 gland morphogenesis The process in which the anatomical structures of the neurohypophysis are generated and organized. The neurohypophysis is the part of the pituitary gland that secretes hormones involved in blood pressure regulation. http://purl.obolibrary.org/obo/GO_1901166 neural crest cell migration involved in autonomic nervous system development http://purl.obolibrary.org/obo/GO_0001755 neural crest cell migration Any neural crest cell migration that is involved in autonomic nervous system development. http://purl.obolibrary.org/obo/GO_0048849 neurohypophysis formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process that gives rise to neurohypophysis. This process pertains to the initial formation of a structure from unspecified parts. The neurohypophysis is the part of the pituitary gland that secretes hormones involved in blood pressure regulation. http://purl.obolibrary.org/obo/GO_1901190 regulation of formation of translation initiation ternary complex http://purl.obolibrary.org/obo/GO_0043254 regulation of protein-containing complex assembly Any process that modulates the frequency, rate or extent of formation of translation initiation ternary complex. http://purl.obolibrary.org/obo/GO_0048850 hypophysis morphogenesis http://purl.obolibrary.org/obo/GO_0022612 gland morphogenesis The process in which the anatomical structures of the hypophysis are generated and organized. The pituitary gland is an endocrine gland that secretes hormones that regulate many other glands. http://purl.obolibrary.org/obo/GO_1901191 negative regulation of formation of translation initiation ternary complex http://purl.obolibrary.org/obo/GO_1901190 regulation of formation of translation initiation ternary complex Any process that stops, prevents or reduces the frequency, rate or extent of formation of translation initiation ternary complex. http://purl.obolibrary.org/obo/GO_0048851 hypophysis formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process in which the anatomical structures of the hypophysis are generated and organized. The hypophysis is an endocrine gland that secretes hormones that regulate many other glands. http://purl.obolibrary.org/obo/GO_1901192 positive regulation of formation of translation initiation ternary complex http://purl.obolibrary.org/obo/GO_1901190 regulation of formation of translation initiation ternary complex Any process that activates or increases the frequency, rate or extent of formation of translation initiation ternary complex. http://purl.obolibrary.org/obo/GO_0048852 diencephalon morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structures of the diencephalon are generated and organized. The diencephalon is the paired caudal parts of the prosencephalon from which the thalamus, hypothalamus, epithalamus and subthalamus are derived; these regions regulate autonomic, visceral and endocrine function, and process information directed to the cerebral cortex. http://purl.obolibrary.org/obo/GO_1901201 regulation of extracellular matrix assembly http://purl.obolibrary.org/obo/GO_1903053 regulation of extracellular matrix organization Any process that modulates the frequency, rate or extent of extracellular matrix assembly. http://purl.obolibrary.org/obo/GO_0048853 forebrain morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structures of the forebrain are generated and organized. The forebrain is the anterior of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes especially the cerebral hemispheres, the thalamus, and the hypothalamus and especially in higher vertebrates is the main control center for sensory and associative information processing, visceral functions, and voluntary motor functions). http://purl.obolibrary.org/obo/GO_1901202 negative regulation of extracellular matrix assembly http://purl.obolibrary.org/obo/GO_1901201 regulation of extracellular matrix assembly Any process that stops, prevents or reduces the frequency, rate or extent of extracellular matrix assembly. http://purl.obolibrary.org/obo/GO_0048854 brain morphogenesis http://purl.obolibrary.org/obo/GO_0009887 animal organ morphogenesis The process in which the anatomical structures of the brain are generated and organized. The brain is one of the two components of the central nervous system and is the center of thought and emotion. It is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.). http://purl.obolibrary.org/obo/GO_1901203 positive regulation of extracellular matrix assembly http://purl.obolibrary.org/obo/GO_0044089 positive regulation of cellular component biogenesis Any process that activates or increases the frequency, rate or extent of extracellular matrix assembly. http://purl.obolibrary.org/obo/GO_0048855 adenohypophysis morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structures of the adenohypophysis are generated and organized. The adenohypophysis is the anterior part of the pituitary. It secretes a variety of hormones and its function is regulated by the hypothalamus. http://purl.obolibrary.org/obo/GO_1901210 regulation of cardiac chamber formation http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of cardiac chamber formation. http://purl.obolibrary.org/obo/GO_0048880 sensory system development http://purl.obolibrary.org/obo/GO_0048731 system development The process whose specific outcome is the progression of a sensory system over time from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_1901211 negative regulation of cardiac chamber formation http://purl.obolibrary.org/obo/GO_1901210 regulation of cardiac chamber formation Any process that stops, prevents or reduces the frequency, rate or extent of cardiac chamber formation. http://purl.obolibrary.org/obo/GO_0048881 mechanosensory lateral line system development http://purl.obolibrary.org/obo/GO_0048925 lateral line system development The process whose specific outcome is the progression of the mechanosensory lateral line system over time, from its formation to the mature structure. The mechanosensory lateral line system consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head and body of all fishes and most amphibians. The neuromasts are innervated by several lateral line nerves, which project primarily to the hindbrain. The mechanosensory lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the fish through the water, as well as facilitating shoaling, prey capture, and predator and obstacle avoidance. http://purl.obolibrary.org/obo/GO_1901212 positive regulation of cardiac chamber formation http://purl.obolibrary.org/obo/GO_1901221 positive regulation of cardiac chamber morphogenesis Any process that activates or increases the frequency, rate or extent of cardiac chamber formation. http://purl.obolibrary.org/obo/GO_0048882 lateral line development http://purl.obolibrary.org/obo/GO_0009888 tissue development The process whose specific outcome is the progression of the lateral line over time, from its formation to the mature structure. The lateral line consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head and body of all fishes and most amphibians. The lateral line develops from cranial ectodermal placodes situated behind the ear and between the eye and ear. http://purl.obolibrary.org/obo/GO_1901219 regulation of cardiac chamber morphogenesis http://purl.obolibrary.org/obo/GO_2000826 regulation of heart morphogenesis Any process that modulates the frequency, rate or extent of cardiac chamber morphogenesis. http://purl.obolibrary.org/obo/GO_0048884 neuromast development http://purl.obolibrary.org/obo/GO_0007423 sensory organ development The process whose specific outcome is the progression of the neuromast over time, from its formation to the mature structure. The neuromast is the sensory organ of the lateral line and is composed of a population of sensory hair cells, and nonsensory supporting cells and mantle cells. Neuromasts are located superficially on the epithelium or in lateral line canals. http://purl.obolibrary.org/obo/GO_1901220 negative regulation of cardiac chamber morphogenesis http://purl.obolibrary.org/obo/GO_1901219 regulation of cardiac chamber morphogenesis Any process that stops, prevents or reduces the frequency, rate or extent of cardiac chamber morphogenesis. http://purl.obolibrary.org/obo/GO_0048888 neuromast mantle cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a neuromast mantle cell. Mantle cells are non-sensory cells that surround the sensory strip, separating the neuromast from the epidermis. Mantle cells secrete the cupula in which the ciliary bundles of all of the hair cells are embedded. http://purl.obolibrary.org/obo/GO_1901221 positive regulation of cardiac chamber morphogenesis http://purl.obolibrary.org/obo/GO_1901219 regulation of cardiac chamber morphogenesis Any process that activates or increases the frequency, rate or extent of cardiac chamber morphogenesis. http://purl.obolibrary.org/obo/GO_0048889 neuromast support cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a neuromast support cell. Support cells are non-sensory cells of the neuromast that extend between the sensory hair cells from the basement membrane to the apical surface; they are surrounded by mantle cells. http://purl.obolibrary.org/obo/GO_1901246 regulation of lung ciliated cell differentiation http://purl.obolibrary.org/obo/GO_0030856 regulation of epithelial cell differentiation Any process that modulates the frequency, rate or extent of lung ciliated cell differentiation. http://purl.obolibrary.org/obo/GO_0048890 lateral line ganglion development http://purl.obolibrary.org/obo/GO_0061550 cranial ganglion development The process whose specific outcome is the progression of the lateral line ganglion over time, from its formation to the mature structure. The lateral line ganglion develops from cranial ectodermal placodes situated between the eye and ear and behind the ear. http://purl.obolibrary.org/obo/GO_1901247 negative regulation of lung ciliated cell differentiation http://purl.obolibrary.org/obo/GO_1901246 regulation of lung ciliated cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of lung ciliated cell differentiation. http://purl.obolibrary.org/obo/GO_0048891 lateral line ganglion neuron differentiation http://purl.obolibrary.org/obo/GO_0048934 peripheral nervous system neuron differentiation The process in which a relatively unspecialized cell acquires specialized features of a lateral line ganglion neuron. http://purl.obolibrary.org/obo/GO_1901248 positive regulation of lung ciliated cell differentiation http://purl.obolibrary.org/obo/GO_1901246 regulation of lung ciliated cell differentiation Any process that activates or increases the frequency, rate or extent of lung ciliated cell differentiation. http://purl.obolibrary.org/obo/GO_0048892 lateral line nerve development http://purl.obolibrary.org/obo/GO_0021545 cranial nerve development The process whose specific outcome is the progression of the lateral line nerve over time, form its formation to the mature structure. Lateral line nerves project primarily to an octavolateralis column in the hindbrain that consists of the medial octavolateralis nucleus (MON), the caudal octavolateralis nucleus, and the magnocellular nucleus. http://purl.obolibrary.org/obo/GO_1901249 regulation of lung goblet cell differentiation http://purl.obolibrary.org/obo/GO_0030856 regulation of epithelial cell differentiation Any process that modulates the frequency, rate or extent of lung goblet cell differentiation. http://purl.obolibrary.org/obo/GO_0048895 lateral line nerve glial cell differentiation http://purl.obolibrary.org/obo/GO_0010001 glial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a glial cell in a lateral line nerve. http://purl.obolibrary.org/obo/GO_1901250 negative regulation of lung goblet cell differentiation http://purl.obolibrary.org/obo/GO_1901249 regulation of lung goblet cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of lung goblet cell differentiation. http://purl.obolibrary.org/obo/GO_0048896 lateral line nerve glial cell migration http://purl.obolibrary.org/obo/GO_0008347 glial cell migration The movement of a glial cell along the axons in a lateral line nerve. http://purl.obolibrary.org/obo/GO_1901379 regulation of potassium ion transmembrane transport http://purl.obolibrary.org/obo/GO_1904062 regulation of monoatomic cation transmembrane transport Any process that modulates the frequency, rate or extent of potassium ion transmembrane transport. http://purl.obolibrary.org/obo/GO_0048898 anterior lateral line system development http://purl.obolibrary.org/obo/GO_0048925 lateral line system development The process whose specific outcome is the progression of the anterior lateral line system over time, from its formation to the mature structure. The anterior lateral line system develops from cranial ectodermal placodes, situated between the eye and the ear, that give rise to both the neuromasts and the anterior lateral line sensory nerves that innervate the neuromasts. The anterior lateral line system consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head of all fishes and most amphibians and are innervated by several lateral line nerves, which project to the hindbrain. The anterior lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the fish through the water, as well as facilitating shoaling, prey capture, and predator and obstacle avoidance. http://purl.obolibrary.org/obo/GO_1901380 negative regulation of potassium ion transmembrane transport http://purl.obolibrary.org/obo/GO_1901379 regulation of potassium ion transmembrane transport Any process that stops, prevents or reduces the frequency, rate or extent of potassium ion transmembrane transport. http://purl.obolibrary.org/obo/GO_0048899 anterior lateral line development http://purl.obolibrary.org/obo/GO_0048882 lateral line development The process whose specific outcome is the progression of the anterior lateral line over time, from its formation to the mature structure. The anterior lateral line consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head of all fishes and most amphibians. The anterior lateral line develops from cranial ectodermal placodes situated between the eye and ear. http://purl.obolibrary.org/obo/GO_1901381 positive regulation of potassium ion transmembrane transport http://purl.obolibrary.org/obo/GO_1901379 regulation of potassium ion transmembrane transport Any process that activates or increases the frequency, rate or extent of potassium ion transmembrane transport. http://purl.obolibrary.org/obo/GO_0048901 anterior lateral line neuromast development http://purl.obolibrary.org/obo/GO_0048884 neuromast development The process whose specific outcome is the progression of the anterior lateral line neuromast over time, from its formation to the mature structure. The neuromast is the sensory receptor of the anterior lateral line system and is composed of a population of sensory hair cells, and nonsensory supporting cells and mantle cells. Neuromast are located superficially on the epithelium or in lateral line canals. http://purl.obolibrary.org/obo/GO_1901858 regulation of mitochondrial DNA metabolic process http://purl.obolibrary.org/obo/GO_0051052 regulation of DNA metabolic process Any process that modulates the frequency, rate or extent of mitochondrial DNA metabolic process. http://purl.obolibrary.org/obo/GO_0048905 anterior lateral line neuromast mantle cell differentiation http://purl.obolibrary.org/obo/GO_0048888 neuromast mantle cell differentiation The process in which a relatively unspecialized cell acquires specialized features of an anterior lateral line neuromast mantle cell. Mantle cells are non-sensory cells that surround the sensory strip, separating the neuromast from the epidermis. Mantle cells secrete the cupula in which the ciliary bundles of all of the hair cells are embedded. http://purl.obolibrary.org/obo/GO_1901859 negative regulation of mitochondrial DNA metabolic process http://purl.obolibrary.org/obo/GO_1901858 regulation of mitochondrial DNA metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial DNA metabolic process. http://purl.obolibrary.org/obo/GO_0048906 anterior lateral line neuromast support cell differentiation http://purl.obolibrary.org/obo/GO_0048889 neuromast support cell differentiation The process in which a relatively unspecialized cell acquires specialized features of an anterior lateral line neuromast support cell. Support cells are non-sensory cells of the neuromast that extend between the sensory hair cells from the basement membrane to the apical surface; they are surrounded by mantle cells. http://purl.obolibrary.org/obo/GO_1901860 positive regulation of mitochondrial DNA metabolic process http://purl.obolibrary.org/obo/GO_0010821 regulation of mitochondrion organization Any process that activates or increases the frequency, rate or extent of mitochondrial DNA metabolic process. http://purl.obolibrary.org/obo/GO_0048907 anterior lateral line ganglion development http://purl.obolibrary.org/obo/GO_0048890 lateral line ganglion development The process whose specific outcome is the progression of the anterior lateral line ganglion over time, from its formation to the mature structure. The anterior lateral line ganglion develops from cranial ectodermal placodes situated between the eye and ear. http://purl.obolibrary.org/obo/GO_1901888 regulation of cell junction assembly http://purl.obolibrary.org/obo/GO_0051128 regulation of cellular component organization Any process that modulates the frequency, rate or extent of cell junction assembly. http://purl.obolibrary.org/obo/GO_0048913 anterior lateral line nerve glial cell differentiation http://purl.obolibrary.org/obo/GO_0048895 lateral line nerve glial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a glial cell in the anterior lateral line nerve. http://purl.obolibrary.org/obo/GO_1901950 dense core granule transport http://purl.obolibrary.org/obo/GO_0032253 dense core granule localization The directed movement a dense core granule within a cell. http://purl.obolibrary.org/obo/GO_0048915 posterior lateral line system development http://purl.obolibrary.org/obo/GO_0048925 lateral line system development The process whose specific outcome is the progression of the posterior lateral line system over time, from its formation to the mature structure. The posterior lateral line system develops from cranial ectodermal placodes, situated behind the ear, that give rise to both the neuromasts and the posterior lateral line sensory nerves that innervate the neuromasts. The posterior lateral line system consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head of all fishes and most amphibians. The neuromasts are innervated by several lateral line nerves, which project primarily to the hindbrain. The posterior mechanosensory lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the fish through the water, as well as facilitating shoaling, prey capture, and predator and obstacle avoidance. http://purl.obolibrary.org/obo/GO_1902622 regulation of neutrophil migration http://purl.obolibrary.org/obo/GO_0002685 regulation of leukocyte migration Any process that modulates the frequency, rate or extent of neutrophil migration. http://purl.obolibrary.org/obo/GO_0048916 posterior lateral line development http://purl.obolibrary.org/obo/GO_0048882 lateral line development The process whose specific outcome is the progression of the posterior lateral line over time, from its formation to the mature structure. The posterior lateral line consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the body and trunk of all fishes and most amphibians. The posterior lateral line develops from cranial ectodermal placodes situated behind the ear. http://purl.obolibrary.org/obo/GO_1902623 negative regulation of neutrophil migration http://purl.obolibrary.org/obo/GO_1902622 regulation of neutrophil migration Any process that stops, prevents or reduces the frequency, rate or extent of neutrophil migration. http://purl.obolibrary.org/obo/GO_0048917 posterior lateral line ganglion development http://purl.obolibrary.org/obo/GO_0048890 lateral line ganglion development The process whose specific outcome is the progression of the posterior lateral line ganglion over time, from its formation to the mature structure. The posterior lateral line ganglion develops from cranial ectodermal placodes situated behind the ear. http://purl.obolibrary.org/obo/GO_1902624 positive regulation of neutrophil migration http://purl.obolibrary.org/obo/GO_1902622 regulation of neutrophil migration Any process that activates or increases the frequency, rate or extent of neutrophil migration. http://purl.obolibrary.org/obo/GO_0048919 posterior lateral line neuromast development http://purl.obolibrary.org/obo/GO_0048884 neuromast development The process whose specific outcome is the progression of the posterior lateral line neuromast over time, from its formation to the mature structure. The neuromast is the sensory receptor of the anterior lateral line system and is composed of a population of sensory hair cells, and nonsensory supporting cells and mantle cells. Neuromast are located superficially on the epithelium or in lateral line canals. http://purl.obolibrary.org/obo/GO_1902656 calcium ion import into cytosol http://purl.obolibrary.org/obo/GO_0006816 calcium ion transport The directed movement of calcium ion into a cytosol. http://purl.obolibrary.org/obo/GO_0048924 posterior lateral line neuromast mantle cell differentiation http://purl.obolibrary.org/obo/GO_0048888 neuromast mantle cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a posterior lateral line neuromast mantle cell. (N.B. This may be development of neuromast mantle cell type or a set of cells of neuromast mantle cell type. This will involve the change of a cell or set of cells from one cell identity to another). Mantle cells are non-sensory cells that surround the sensory strip, separating the neuromast from the epidermis. Mantle cells secrete the cupula in which the ciliary bundles of all of the hair cells are embedded. http://purl.obolibrary.org/obo/GO_1902882 regulation of response to oxidative stress http://purl.obolibrary.org/obo/GO_0080134 regulation of response to stress Any process that modulates the frequency, rate or extent of response to oxidative stress. http://purl.obolibrary.org/obo/GO_0048925 lateral line system development http://purl.obolibrary.org/obo/GO_0048880 sensory system development The process whose specific outcome is the progression of the lateral line system over time, from its formation to the mature structure. The lateral line system is a network of sensory organs (neuromasts) and lateral line nerves located superficially on the skin or just under the skin in fluid-filled canals on the head and body of all fishes and most amphibians. The lateral line system develops from cranial ectodermal placodes situated between the eye and ear. http://purl.obolibrary.org/obo/GO_1902883 negative regulation of response to oxidative stress http://purl.obolibrary.org/obo/GO_1902882 regulation of response to oxidative stress Any process that stops, prevents or reduces the frequency, rate or extent of response to oxidative stress. http://purl.obolibrary.org/obo/GO_0048927 posterior lateral line neuromast support cell differentiation http://purl.obolibrary.org/obo/GO_0048889 neuromast support cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a posterior lateral line neuromast support cell. Support cells are non-sensory cells of the neuromast that extend between the sensory hair cells from the basement membrane to the apical surface; they are surrounded by mantle cells. http://purl.obolibrary.org/obo/GO_1902884 positive regulation of response to oxidative stress http://purl.obolibrary.org/obo/GO_1902882 regulation of response to oxidative stress Any process that activates or increases the frequency, rate or extent of response to oxidative stress. http://purl.obolibrary.org/obo/GO_0048928 posterior lateral line ganglion neuron differentiation http://purl.obolibrary.org/obo/GO_0048891 lateral line ganglion neuron differentiation The process in which a relatively unspecialized cell acquires specialized features of a neuron of the posterior lateral line ganglion. http://purl.obolibrary.org/obo/GO_1903011 negative regulation of bone development http://purl.obolibrary.org/obo/GO_1903010 regulation of bone development Any process that stops, prevents or reduces the frequency, rate or extent of bone development. http://purl.obolibrary.org/obo/GO_0048931 posterior lateral line nerve glial cell differentiation http://purl.obolibrary.org/obo/GO_0048895 lateral line nerve glial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a glial cell in the posterior lateral line nerve. http://purl.obolibrary.org/obo/GO_1903012 positive regulation of bone development http://purl.obolibrary.org/obo/GO_1903010 regulation of bone development Any process that activates or increases the frequency, rate or extent of bone development. http://purl.obolibrary.org/obo/GO_0048934 peripheral nervous system neuron differentiation http://purl.obolibrary.org/obo/GO_0030182 neuron differentiation The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the peripheral nervous system. http://purl.obolibrary.org/obo/GO_1903076 regulation of protein localization to plasma membrane http://purl.obolibrary.org/obo/GO_1904375 regulation of protein localization to cell periphery Any process that modulates the frequency, rate or extent of protein localization to plasma membrane. http://purl.obolibrary.org/obo/GO_1903077 negative regulation of protein localization to plasma membrane http://purl.obolibrary.org/obo/GO_1904376 negative regulation of protein localization to cell periphery Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to plasma membrane. http://purl.obolibrary.org/obo/GO_0048935 peripheral nervous system neuron development http://purl.obolibrary.org/obo/GO_0048666 neuron development The process whose specific outcome is the progression of a neuron whose cell body is located in the peripheral nervous system, from initial commitment of the cell to a neuronal fate, to the fully functional differentiated neuron. http://purl.obolibrary.org/obo/GO_1903078 positive regulation of protein localization to plasma membrane http://purl.obolibrary.org/obo/GO_1904377 positive regulation of protein localization to cell periphery Any process that activates or increases the frequency, rate or extent of protein localization to plasma membrane. http://purl.obolibrary.org/obo/GO_1903251 multi-ciliated epithelial cell differentiation http://purl.obolibrary.org/obo/GO_0002065 columnar/cuboidal epithelial cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a multi-ciliated epithelial cell. http://purl.obolibrary.org/obo/GO_0048937 lateral line nerve glial cell development http://purl.obolibrary.org/obo/GO_0021782 glial cell development The process aimed at the progression of a lateral line glial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. http://purl.obolibrary.org/obo/GO_1903327 negative regulation of tRNA metabolic process http://purl.obolibrary.org/obo/GO_1903326 regulation of tRNA metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of tRNA metabolic process. http://purl.obolibrary.org/obo/GO_0048939 anterior lateral line nerve glial cell development http://purl.obolibrary.org/obo/GO_0048937 lateral line nerve glial cell development The process aimed at the progression of a glial cell in the anterior lateral line nerve over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. http://purl.obolibrary.org/obo/GO_1903335 regulation of vacuolar transport http://purl.obolibrary.org/obo/GO_0032386 regulation of intracellular transport Any process that modulates the frequency, rate or extent of vacuolar transport. http://purl.obolibrary.org/obo/GO_0048940 anterior lateral line nerve glial cell morphogenesis involved in differentiation http://purl.obolibrary.org/obo/GO_0000902 cell morphogenesis The process in which the structures of a glial cell in the anterior lateral line nerve are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a glial cell in the anterior lateral line nerve. http://purl.obolibrary.org/obo/GO_1903336 negative regulation of vacuolar transport http://purl.obolibrary.org/obo/GO_1903335 regulation of vacuolar transport Any process that stops, prevents or reduces the frequency, rate or extent of vacuolar transport. http://purl.obolibrary.org/obo/GO_0048941 posterior lateral line nerve glial cell development http://purl.obolibrary.org/obo/GO_0048937 lateral line nerve glial cell development The process aimed at the progression of a glial cell in the posterior lateral line nerve over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. http://purl.obolibrary.org/obo/GO_1903337 positive regulation of vacuolar transport http://purl.obolibrary.org/obo/GO_1903335 regulation of vacuolar transport Any process that activates or increases the frequency, rate or extent of vacuolar transport. http://purl.obolibrary.org/obo/GO_0048942 posterior lateral line nerve glial cell morphogenesis involved in differentiation http://purl.obolibrary.org/obo/GO_0000902 cell morphogenesis The process in which the structures of a glial cell in the posterior lateral line nerve are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a glial cell in the posterior lateral line nerve. http://purl.obolibrary.org/obo/GO_1903358 regulation of Golgi organization http://purl.obolibrary.org/obo/GO_0033043 regulation of organelle organization Any process that modulates the frequency, rate or extent of Golgi organization. http://purl.obolibrary.org/obo/GO_0050657 nucleic acid transport http://purl.obolibrary.org/obo/GO_0015931 nucleobase-containing compound transport The directed movement of nucleic acids, single or double-stranded polynucleotides involved in the storage, transmission and transfer of genetic information, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_1903441 protein localization to ciliary membrane http://purl.obolibrary.org/obo/GO_0061512 protein localization to cilium A process in which a protein is transported to, or maintained in, a location within a ciliary membrane. http://purl.obolibrary.org/obo/GO_0050674 urothelial cell proliferation http://purl.obolibrary.org/obo/GO_0050673 epithelial cell proliferation The multiplication or reproduction of urothelial cells, resulting in the expansion of a cell population. Urothelial cells make up a layer of transitional epithelium in the wall of the bladder, ureter, and renal pelvis, external to the lamina propria. http://purl.obolibrary.org/obo/GO_1903539 protein localization to postsynaptic membrane http://purl.obolibrary.org/obo/GO_0062237 protein localization to postsynapse A process in which a protein is transported to, or maintained in, a location within a postsynaptic membrane. http://purl.obolibrary.org/obo/GO_0050675 regulation of urothelial cell proliferation http://purl.obolibrary.org/obo/GO_0050678 regulation of epithelial cell proliferation Any process that modulates the frequency, rate or extent of urothelial cell proliferation. http://purl.obolibrary.org/obo/GO_1903540 establishment of protein localization to postsynaptic membrane http://purl.obolibrary.org/obo/GO_0090150 establishment of protein localization to membrane The directed movement of a protein to a specific location in a postsynaptic membrane. http://purl.obolibrary.org/obo/GO_0050676 negative regulation of urothelial cell proliferation http://purl.obolibrary.org/obo/GO_0050680 negative regulation of epithelial cell proliferation Any process that stops, prevents or reduces the rate or extent of urothelial cell proliferation. http://purl.obolibrary.org/obo/GO_1903747 regulation of protein localization to mitochondrion http://purl.obolibrary.org/obo/GO_0032880 regulation of protein localization Any process that modulates the frequency, rate or extent of protein localization to mitochondrion. http://purl.obolibrary.org/obo/GO_0050677 positive regulation of urothelial cell proliferation http://purl.obolibrary.org/obo/GO_0050679 positive regulation of epithelial cell proliferation Any process that activates or increases the rate or extent of urothelial cell proliferation. http://purl.obolibrary.org/obo/GO_1903749 positive regulation of protein localization to mitochondrion http://purl.obolibrary.org/obo/GO_1903829 positive regulation of protein localization Any process that activates or increases the frequency, rate or extent of protein localization to mitochondrion. http://purl.obolibrary.org/obo/GO_0050708 regulation of protein secretion http://purl.obolibrary.org/obo/GO_0051223 regulation of protein transport Any process that modulates the frequency, rate or extent of the controlled release of a protein from a cell. http://purl.obolibrary.org/obo/GO_1903779 regulation of cardiac conduction http://purl.obolibrary.org/obo/GO_0008016 regulation of heart contraction Any process that modulates the frequency, rate or extent of cardiac conduction. http://purl.obolibrary.org/obo/GO_0050709 negative regulation of protein secretion http://purl.obolibrary.org/obo/GO_0051224 negative regulation of protein transport Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a protein from a cell. http://purl.obolibrary.org/obo/GO_1903810 L-histidine import across plasma membrane http://purl.obolibrary.org/obo/GO_0089718 amino acid import across plasma membrane The directed movement of L-histidine from outside of a cell, across the plasma membrane and into the cytosol. http://purl.obolibrary.org/obo/GO_0050747 positive regulation of lipoprotein metabolic process http://purl.obolibrary.org/obo/GO_0009891 positive regulation of biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving lipoproteins, any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids. http://purl.obolibrary.org/obo/GO_1903829 positive regulation of protein localization http://purl.obolibrary.org/obo/GO_0032880 regulation of protein localization Any process that activates or increases the frequency, rate or extent of a protein localization. http://purl.obolibrary.org/obo/GO_0050764 regulation of phagocytosis http://purl.obolibrary.org/obo/GO_0030100 regulation of endocytosis Any process that modulates the frequency, rate or extent of phagocytosis, the process in which phagocytes engulf external particulate material. http://purl.obolibrary.org/obo/GO_1903831 signal transduction involved in cellular response to ammonium ion http://purl.obolibrary.org/obo/GO_0007165 signal transduction Any signal transduction that is involved in cellular response to ammonium ion. http://purl.obolibrary.org/obo/GO_0050765 negative regulation of phagocytosis http://purl.obolibrary.org/obo/GO_0050764 regulation of phagocytosis Any process that stops, prevents, or reduces the frequency, rate or extent of phagocytosis. http://purl.obolibrary.org/obo/GO_1903975 regulation of glial cell migration http://purl.obolibrary.org/obo/GO_0030334 regulation of cell migration Any process that modulates the frequency, rate or extent of glial cell migration. http://purl.obolibrary.org/obo/GO_0050766 positive regulation of phagocytosis http://purl.obolibrary.org/obo/GO_0050764 regulation of phagocytosis Any process that activates or increases the frequency, rate or extent of phagocytosis. http://purl.obolibrary.org/obo/GO_1903977 positive regulation of glial cell migration http://purl.obolibrary.org/obo/GO_1903975 regulation of glial cell migration Any process that activates or increases the frequency, rate or extent of glial cell migration. http://purl.obolibrary.org/obo/GO_0050773 regulation of dendrite development http://purl.obolibrary.org/obo/GO_0010975 regulation of neuron projection development Any process that modulates the frequency, rate or extent of dendrite development. http://purl.obolibrary.org/obo/GO_0050774 negative regulation of dendrite morphogenesis http://purl.obolibrary.org/obo/GO_0048814 regulation of dendrite morphogenesis Any process that stops, prevents, or reduces the frequency, rate or extent of dendrite morphogenesis. http://purl.obolibrary.org/obo/GO_1904587 response to glycoprotein http://purl.obolibrary.org/obo/GO_1901700 response to oxygen-containing compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycoprotein stimulus. http://purl.obolibrary.org/obo/GO_0050775 positive regulation of dendrite morphogenesis http://purl.obolibrary.org/obo/GO_0031346 positive regulation of cell projection organization Any process that activates or increases the frequency, rate or extent of dendrite morphogenesis. http://purl.obolibrary.org/obo/GO_1904688 regulation of cytoplasmic translational initiation http://purl.obolibrary.org/obo/GO_2000765 regulation of cytoplasmic translation Any process that modulates the frequency, rate or extent of cytoplasmic translational initiation. http://purl.obolibrary.org/obo/GO_0050803 regulation of synapse structure or activity http://purl.obolibrary.org/obo/GO_0065008 regulation of biological quality Any process that modulates the physical form or the activity of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell). http://purl.obolibrary.org/obo/GO_1904689 negative regulation of cytoplasmic translational initiation http://purl.obolibrary.org/obo/GO_1904688 regulation of cytoplasmic translational initiation Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic translational initiation. http://purl.obolibrary.org/obo/GO_0050807 regulation of synapse organization http://purl.obolibrary.org/obo/GO_0051128 regulation of cellular component organization Any process that modulates the physical form of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell). http://purl.obolibrary.org/obo/GO_1904690 positive regulation of cytoplasmic translational initiation http://purl.obolibrary.org/obo/GO_1904688 regulation of cytoplasmic translational initiation Any process that activates or increases the frequency, rate or extent of cytoplasmic translational initiation. http://purl.obolibrary.org/obo/GO_0050825 ice binding http://purl.obolibrary.org/obo/GO_0036094 small molecule binding Binding to ice, water reduced to the solid state by cold temperature. It is a white or transparent colorless substance, crystalline, brittle, and viscoidal. http://purl.obolibrary.org/obo/GO_1904861 excitatory synapse assembly http://purl.obolibrary.org/obo/GO_0007416 synapse assembly The aggregation, arrangement and bonding together of a set of components to form an excitatory synapse. http://purl.obolibrary.org/obo/GO_0050872 white fat cell differentiation http://purl.obolibrary.org/obo/GO_0045444 fat cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a white adipocyte, an animal connective tissue cell involved in energy storage. White adipocytes have cytoplasmic lipids arranged in a unique vacuole. http://purl.obolibrary.org/obo/GO_1904970 brush border assembly http://purl.obolibrary.org/obo/GO_0022607 cellular component assembly The aggregation, arrangement and bonding together of adjacent microvilli through the formation of Ca(2+)-dependent adhesion links between them, forming a brush border. http://purl.obolibrary.org/obo/GO_0050873 brown fat cell differentiation http://purl.obolibrary.org/obo/GO_0045444 fat cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a brown adipocyte, an animal connective tissue cell involved in adaptive thermogenesis. Brown adipocytes contain multiple small droplets of triglycerides and a high number of mitochondria. http://purl.obolibrary.org/obo/GO_1905270 Meynert cell differentiation http://purl.obolibrary.org/obo/GO_0021895 cerebral cortex neuron differentiation The process in which a relatively unspecialized cell acquires the specialized features of a Meynert cell. http://purl.obolibrary.org/obo/GO_0050885 neuromuscular process controlling balance http://purl.obolibrary.org/obo/GO_0050905 neuromuscular process Any process that an organism uses to control its balance, the orientation of the organism (or the head of the organism) in relation to the source of gravity. In humans and animals, balance is perceived through visual cues, the labyrinth system of the inner ears and information from skin pressure receptors and muscle and joint receptors. http://purl.obolibrary.org/obo/GO_1905383 protein localization to presynapse http://purl.obolibrary.org/obo/GO_0035418 protein localization to synapse A process in which a protein is transported to, or maintained in, a location within a presynapse. http://purl.obolibrary.org/obo/GO_0050893 sensory processing http://purl.obolibrary.org/obo/GO_0050890 cognition Any neural process required for an organism to sense and interpret the dimensions of a sensory experience: modality, location, intensity and affect. http://purl.obolibrary.org/obo/GO_1905475 regulation of protein localization to membrane http://purl.obolibrary.org/obo/GO_0060341 regulation of cellular localization Any process that modulates the frequency, rate or extent of protein localization to membrane. http://purl.obolibrary.org/obo/GO_0050906 detection of stimulus involved in sensory perception http://purl.obolibrary.org/obo/GO_0051606 detection of stimulus The series of events involved in sensory perception in which a sensory stimulus is received and converted into a molecular signal. http://purl.obolibrary.org/obo/GO_1905476 negative regulation of protein localization to membrane http://purl.obolibrary.org/obo/GO_1903828 negative regulation of protein localization Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to membrane. http://purl.obolibrary.org/obo/GO_0050907 detection of chemical stimulus involved in sensory perception http://purl.obolibrary.org/obo/GO_0009593 detection of chemical stimulus The series of events in which a chemical stimulus is received and converted into a molecular signal as part of sensory perception. http://purl.obolibrary.org/obo/GO_1905477 positive regulation of protein localization to membrane http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the frequency, rate or extent of protein localization to membrane. http://purl.obolibrary.org/obo/GO_0050908 detection of light stimulus involved in visual perception http://purl.obolibrary.org/obo/GO_0050962 detection of light stimulus involved in sensory perception The series of events involved in visual perception in which a light stimulus is received and converted into a molecular signal. http://purl.obolibrary.org/obo/GO_1990182 exosomal secretion http://purl.obolibrary.org/obo/GO_0051650 establishment of vesicle localization The process whereby a membrane-bounded vesicle is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. http://purl.obolibrary.org/obo/GO_0050909 sensory perception of taste http://purl.obolibrary.org/obo/GO_0007606 sensory perception of chemical stimulus The series of events required for an organism to receive a gustatory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Gustation involves the direct detection of chemical composition, usually through contact with chemoreceptor cells. This is a neurological process. http://purl.obolibrary.org/obo/GO_1990716 axonemal central apparatus http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure Part of the 9+2 axoneme, that occurs in most motile cilia, consisting of the pair of two single central microtubules and their associated structures which include the central pair projections, the central pair bridges linking the two tubules, and the central pair caps which are attached to the distal or plus ends of the microtubules. http://purl.obolibrary.org/obo/GO_0050935 iridophore differentiation http://purl.obolibrary.org/obo/GO_0050931 pigment cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of an iridophore. Iridophores are pigment cells derived from the neural crest. They contain guanidine or other purine crystals deposited in stacks called reflecting platets or iridisomes. This gives them a silver, gold, or iridescent appearance. http://purl.obolibrary.org/obo/GO_1990719 C1 axonemal microtubule http://purl.obolibrary.org/obo/GO_0005879 axonemal microtubule One of two microtubules present in the axonemal central pair. It is distinguishable from the C2 axonemal microtubule (also called C2 tubule) by the presence of differing protein components of the projections. http://purl.obolibrary.org/obo/GO_0050936 xanthophore differentiation http://purl.obolibrary.org/obo/GO_0050931 pigment cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a xanthophore cell. Xanthophores are pigment cells derived from the neural crest. They contain pteridine and/or carotenoid pigments in structures called pterinosomes or xanthosomes. This makes them yellow to orange in appearance. http://purl.obolibrary.org/obo/GO_1990720 C2 axonemal microtubule http://purl.obolibrary.org/obo/GO_0005879 axonemal microtubule One of two microtubules present in the axonemal central pair. It is distinguishable from the C1 axonemal microtubule (also called C1 tubule) by the presence of differing protein components of the projections. http://purl.obolibrary.org/obo/GO_0050937 regulation of iridophore differentiation http://purl.obolibrary.org/obo/GO_0050932 regulation of pigment cell differentiation Any process that modulates the frequency, rate or extent of iridophore differentiation. http://purl.obolibrary.org/obo/GO_2000068 regulation of defense response to insect http://purl.obolibrary.org/obo/GO_0031347 regulation of defense response Any process that modulates the frequency, rate or extent of defense response to insect. http://purl.obolibrary.org/obo/GO_2000282 regulation of amino acid biosynthetic process http://purl.obolibrary.org/obo/GO_0009889 regulation of biosynthetic process Any process that modulates the frequency, rate or extent of cellular amino acid biosynthetic process. http://purl.obolibrary.org/obo/GO_0050938 regulation of xanthophore differentiation http://purl.obolibrary.org/obo/GO_0050932 regulation of pigment cell differentiation Any process that modulates the frequency, rate or extent of xanthophore differentiation. http://purl.obolibrary.org/obo/GO_2000283 negative regulation of amino acid biosynthetic process http://purl.obolibrary.org/obo/GO_0009890 negative regulation of biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of an amino acid biosynthetic process. http://purl.obolibrary.org/obo/GO_0050943 negative regulation of iridophore differentiation http://purl.obolibrary.org/obo/GO_0050941 negative regulation of pigment cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of iridophore differentiation. http://purl.obolibrary.org/obo/GO_2000284 positive regulation of amino acid biosynthetic process http://purl.obolibrary.org/obo/GO_0009891 positive regulation of biosynthetic process Any process that activates or increases the frequency, rate or extent of cellular amino acid biosynthetic process. http://purl.obolibrary.org/obo/GO_2000380 regulation of mesoderm development http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of mesoderm development. http://purl.obolibrary.org/obo/GO_0050944 negative regulation of xanthophore differentiation http://purl.obolibrary.org/obo/GO_0050941 negative regulation of pigment cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of xanthophore differentiation. http://purl.obolibrary.org/obo/GO_2000381 negative regulation of mesoderm development http://purl.obolibrary.org/obo/GO_2000380 regulation of mesoderm development Any process that stops, prevents or reduces the frequency, rate or extent of mesoderm development. http://purl.obolibrary.org/obo/GO_0050945 positive regulation of iridophore differentiation http://purl.obolibrary.org/obo/GO_0050942 positive regulation of pigment cell differentiation Any process that activates or increases the frequency, rate or extent of iridophore differentiation. http://purl.obolibrary.org/obo/GO_2000382 positive regulation of mesoderm development http://purl.obolibrary.org/obo/GO_2000380 regulation of mesoderm development Any process that activates or increases the frequency, rate or extent of mesoderm development. http://purl.obolibrary.org/obo/GO_0050946 positive regulation of xanthophore differentiation http://purl.obolibrary.org/obo/GO_0050942 positive regulation of pigment cell differentiation Any process that activates or increases the frequency, rate or extent of xanthophore differentiation. http://purl.obolibrary.org/obo/GO_2000425 regulation of apoptotic cell clearance http://purl.obolibrary.org/obo/GO_0050764 regulation of phagocytosis Any process that modulates the frequency, rate or extent of apoptotic cell clearance. http://purl.obolibrary.org/obo/GO_0050951 sensory perception of temperature stimulus http://purl.obolibrary.org/obo/GO_0007600 sensory perception The series of events required for an organism to receive a sensory temperature stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. http://purl.obolibrary.org/obo/GO_2000426 negative regulation of apoptotic cell clearance http://purl.obolibrary.org/obo/GO_2000425 regulation of apoptotic cell clearance Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic cell clearance. http://purl.obolibrary.org/obo/GO_0050952 sensory perception of electrical stimulus http://purl.obolibrary.org/obo/GO_0007600 sensory perception The series of events required for an organism to receive a sensory electrical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. http://purl.obolibrary.org/obo/GO_2000427 positive regulation of apoptotic cell clearance http://purl.obolibrary.org/obo/GO_2000425 regulation of apoptotic cell clearance Any process that activates or increases the frequency, rate or extent of apoptotic cell clearance. http://purl.obolibrary.org/obo/GO_0050955 thermoception http://purl.obolibrary.org/obo/GO_0050951 sensory perception of temperature stimulus The series of events required for an organism to receive a temperature stimulus, convert it to a molecular signal, and recognize and characterize the signal. Thermoception in larger animals is mainly done in the skin; mammals have at least two types of sensor, for detecting heat (temperatures above body temperature) and cold (temperatures below body temperature). http://purl.obolibrary.org/obo/GO_2000523 regulation of T cell costimulation http://purl.obolibrary.org/obo/GO_0050863 regulation of T cell activation Any process that modulates the frequency, rate or extent of T cell costimulation. http://purl.obolibrary.org/obo/GO_0050956 electroception http://purl.obolibrary.org/obo/GO_0050952 sensory perception of electrical stimulus The series of events required for an organism to receive an electrical stimulus, convert it to a molecular signal, and recognize and characterize the signal. Many fish possess an electroception sense; for example, the electric eel uses low voltage pulses of electricity for navigation and prey location. http://purl.obolibrary.org/obo/GO_2000524 negative regulation of T cell costimulation http://purl.obolibrary.org/obo/GO_2000523 regulation of T cell costimulation Any process that stops, prevents or reduces the frequency, rate or extent of T cell costimulation. http://purl.obolibrary.org/obo/GO_0050957 equilibrioception http://purl.obolibrary.org/obo/GO_0007600 sensory perception The series of events required for an organism to receive an orientational stimulus, convert it to a molecular signal, and recognize and characterize the signal. Equilibrioception refers to a combination of processes by which an organism can perceive its orientation with respect to gravity. In animals, stimuli come from labyrinth system of the inner ears, monitoring the direction of motion; visual stimuli, with information on orientation and motion; pressure receptors, which tell the organism which body surfaces are in contact with the ground; and proprioceptive cues, which report which parts of the body are in motion. http://purl.obolibrary.org/obo/GO_2000525 positive regulation of T cell costimulation http://purl.obolibrary.org/obo/GO_2000523 regulation of T cell costimulation Any process that activates or increases the frequency, rate or extent of T cell costimulation. http://purl.obolibrary.org/obo/GO_0050960 detection of temperature stimulus involved in thermoception http://purl.obolibrary.org/obo/GO_0050961 detection of temperature stimulus involved in sensory perception The series of events in which a temperature stimulus is received and converted into a molecular signal as part of thermoception. http://purl.obolibrary.org/obo/GO_2000765 regulation of cytoplasmic translation http://purl.obolibrary.org/obo/GO_0006417 regulation of translation Any process that modulates the frequency, rate or extent of cytoplasmic translation. http://purl.obolibrary.org/obo/GO_0050961 detection of temperature stimulus involved in sensory perception http://purl.obolibrary.org/obo/GO_0016048 detection of temperature stimulus The series of events in which a temperature stimulus is received and converted into a molecular signal as part of sensory perception. http://purl.obolibrary.org/obo/GO_2000766 negative regulation of cytoplasmic translation http://purl.obolibrary.org/obo/GO_2000765 regulation of cytoplasmic translation Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic translation. http://purl.obolibrary.org/obo/GO_0050962 detection of light stimulus involved in sensory perception http://purl.obolibrary.org/obo/GO_0050906 detection of stimulus involved in sensory perception The series of events in which a light stimulus is received by a cell and converted into a molecular signal as part of the sensory perception of light. http://purl.obolibrary.org/obo/GO_2000767 positive regulation of cytoplasmic translation http://purl.obolibrary.org/obo/GO_0045727 positive regulation of translation Any process that activates or increases the frequency, rate or extent of cytoplasmic translation. http://purl.obolibrary.org/obo/GO_0050965 detection of temperature stimulus involved in sensory perception of pain http://purl.obolibrary.org/obo/GO_0050961 detection of temperature stimulus involved in sensory perception The series of events involved in the perception of pain in which a temperature stimulus is received and converted into a molecular signal. http://purl.obolibrary.org/obo/GO_2001233 regulation of apoptotic signaling pathway http://purl.obolibrary.org/obo/GO_0042981 regulation of apoptotic process Any process that modulates the frequency, rate or extent of apoptotic signaling pathway. http://purl.obolibrary.org/obo/GO_0050966 detection of mechanical stimulus involved in sensory perception of pain http://purl.obolibrary.org/obo/GO_0050974 detection of mechanical stimulus involved in sensory perception The series of events involved in the perception of pain in which a mechanical stimulus is received and converted into a molecular signal. http://purl.obolibrary.org/obo/GO_2001234 negative regulation of apoptotic signaling pathway http://purl.obolibrary.org/obo/GO_2001233 regulation of apoptotic signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic signaling pathway. http://purl.obolibrary.org/obo/GO_0050968 detection of chemical stimulus involved in sensory perception of pain http://purl.obolibrary.org/obo/GO_0050907 detection of chemical stimulus involved in sensory perception The series of events involved in the perception of pain in which a chemical stimulus is received and converted into a molecular signal. http://purl.obolibrary.org/obo/GO_2001235 positive regulation of apoptotic signaling pathway http://purl.obolibrary.org/obo/GO_0043065 positive regulation of apoptotic process Any process that activates or increases the frequency, rate or extent of apoptotic signaling pathway. http://purl.obolibrary.org/obo/GO_0050973 detection of mechanical stimulus involved in equilibrioception http://purl.obolibrary.org/obo/GO_0050974 detection of mechanical stimulus involved in sensory perception The series of events involved in equilibrioception in which a mechanical stimulus is received and converted into a molecular signal. During equilibrioception, mechanical stimuli may be in the form of input from pressure receptors or from the labyrinth system of the inner ears. http://purl.obolibrary.org/obo/GO_1901251 positive regulation of lung goblet cell differentiation http://purl.obolibrary.org/obo/GO_1901249 regulation of lung goblet cell differentiation Any process that activates or increases the frequency, rate or extent of lung goblet cell differentiation. http://purl.obolibrary.org/obo/GO_0050974 detection of mechanical stimulus involved in sensory perception http://purl.obolibrary.org/obo/GO_0050982 detection of mechanical stimulus The series of events in which a mechanical stimulus is received and converted into a molecular signal as part of sensory perception. http://purl.obolibrary.org/obo/GO_1901317 regulation of flagellated sperm motility http://purl.obolibrary.org/obo/GO_0060295 regulation of cilium movement involved in cell motility Any process that modulates the frequency, rate or extent of flagellated sperm motility. http://purl.obolibrary.org/obo/GO_0050975 sensory perception of touch http://purl.obolibrary.org/obo/GO_0050954 sensory perception of mechanical stimulus The series of events required for an organism to receive a touch stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. The perception of touch in animals is mediated by mechanoreceptors in the skin and mucous membranes and is the sense by which contact with objects gives evidence as to certain of their qualities. Different types of touch can be perceived (for example, light, coarse, pressure and tickling) and the stimulus may be external or internal (e.g. the feeling of a full stomach). http://purl.obolibrary.org/obo/GO_1901318 negative regulation of flagellated sperm motility http://purl.obolibrary.org/obo/GO_2000242 negative regulation of reproductive process Any process that stops, prevents or reduces the frequency, rate or extent of flagellated sperm motility. http://purl.obolibrary.org/obo/GO_0050976 detection of mechanical stimulus involved in sensory perception of touch http://purl.obolibrary.org/obo/GO_0050974 detection of mechanical stimulus involved in sensory perception The series of events involved in the perception of touch in which a mechanical stimulus is received and converted into a molecular signal. http://purl.obolibrary.org/obo/GO_1901329 regulation of odontoblast differentiation http://purl.obolibrary.org/obo/GO_0030856 regulation of epithelial cell differentiation Any process that modulates the frequency, rate or extent of odontoblast differentiation. http://purl.obolibrary.org/obo/GO_0051032 nucleic acid transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022884 macromolecule transmembrane transporter activity Enables the transfer of nucleic acids from one side of a membrane to the other. Nucleic acids are single or double-stranded polynucleotides involved in the storage, transmission and transfer of genetic information. http://purl.obolibrary.org/obo/GO_1901330 negative regulation of odontoblast differentiation http://purl.obolibrary.org/obo/GO_1901329 regulation of odontoblast differentiation Any process that stops, prevents or reduces the frequency, rate or extent of odontoblast differentiation. http://purl.obolibrary.org/obo/GO_0051033 RNA transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0051032 nucleic acid transmembrane transporter activity Enables the transfer of RNA, ribonucleic acid, from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_1901331 positive regulation of odontoblast differentiation http://purl.obolibrary.org/obo/GO_1901329 regulation of odontoblast differentiation Any process that activates or increases the frequency, rate or extent of odontoblast differentiation. http://purl.obolibrary.org/obo/GO_0051034 tRNA transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0051033 RNA transmembrane transporter activity Enables the transfer of tRNA, transfer ribonucleic acid, from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_1901382 regulation of chorionic trophoblast cell proliferation http://purl.obolibrary.org/obo/GO_0042127 regulation of cell population proliferation Any process that modulates the frequency, rate or extent of chorionic trophoblast cell proliferation. http://purl.obolibrary.org/obo/GO_0051059 NF-kappaB binding http://purl.obolibrary.org/obo/GO_0061629 RNA polymerase II-specific DNA-binding transcription factor binding Binding to NF-kappaB, a transcription factor for eukaryotic RNA polymerase II promoters. http://purl.obolibrary.org/obo/GO_1901383 negative regulation of chorionic trophoblast cell proliferation http://purl.obolibrary.org/obo/GO_0008285 negative regulation of cell population proliferation Any process that stops, prevents or reduces the frequency, rate or extent of chorionic trophoblast cell proliferation. http://purl.obolibrary.org/obo/GO_0051078 meiotic nuclear membrane disassembly http://purl.obolibrary.org/obo/GO_1903046 meiotic cell cycle process The cell cycle process in which the controlled breakdown of the nuclear membranes during meiotic cell division occurs. http://purl.obolibrary.org/obo/GO_1901384 positive regulation of chorionic trophoblast cell proliferation http://purl.obolibrary.org/obo/GO_1901382 regulation of chorionic trophoblast cell proliferation Any process that activates or increases the frequency, rate or extent of chorionic trophoblast cell proliferation. http://purl.obolibrary.org/obo/GO_0051080 meiosis II nuclear membrane disassembly http://purl.obolibrary.org/obo/GO_0051078 meiotic nuclear membrane disassembly The controlled breakdown of the nuclear membranes during the second division of meiosis. http://purl.obolibrary.org/obo/GO_0051133 regulation of NK T cell activation http://purl.obolibrary.org/obo/GO_0046634 regulation of alpha-beta T cell activation Any process that modulates the frequency, rate or extent of natural killer T cell activation. http://purl.obolibrary.org/obo/GO_1901386 negative regulation of voltage-gated calcium channel activity http://purl.obolibrary.org/obo/GO_1901385 regulation of voltage-gated calcium channel activity Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated calcium channel activity. http://purl.obolibrary.org/obo/GO_0051134 negative regulation of NK T cell activation http://purl.obolibrary.org/obo/GO_0051133 regulation of NK T cell activation Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer T cell activation. http://purl.obolibrary.org/obo/GO_1901387 positive regulation of voltage-gated calcium channel activity http://purl.obolibrary.org/obo/GO_1901385 regulation of voltage-gated calcium channel activity Any process that activates or increases the frequency, rate or extent of voltage-gated calcium channel activity. http://purl.obolibrary.org/obo/GO_0051135 positive regulation of NK T cell activation http://purl.obolibrary.org/obo/GO_0051133 regulation of NK T cell activation Any process that activates or increases the frequency, rate or extent of natural killer T cell activation. http://purl.obolibrary.org/obo/GO_1901472 regulation of Golgi calcium ion export http://purl.obolibrary.org/obo/GO_0051279 regulation of release of sequestered calcium ion into cytosol Any process that modulates the frequency, rate or extent of Golgi calcium ion export. http://purl.obolibrary.org/obo/GO_0051136 regulation of NK T cell differentiation http://purl.obolibrary.org/obo/GO_0046637 regulation of alpha-beta T cell differentiation Any process that modulates the frequency, rate or extent of natural killer T cell differentiation. http://purl.obolibrary.org/obo/GO_0051137 negative regulation of NK T cell differentiation http://purl.obolibrary.org/obo/GO_0046639 negative regulation of alpha-beta T cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer T cell differentiation. http://purl.obolibrary.org/obo/GO_1901490 regulation of lymphangiogenesis http://purl.obolibrary.org/obo/GO_0022603 regulation of anatomical structure morphogenesis Any process that modulates the frequency, rate or extent of lymphangiogenesis. http://purl.obolibrary.org/obo/GO_0051138 positive regulation of NK T cell differentiation http://purl.obolibrary.org/obo/GO_0046638 positive regulation of alpha-beta T cell differentiation Any process that activates or increases the frequency, rate or extent of natural killer T cell differentiation. http://purl.obolibrary.org/obo/GO_1901491 negative regulation of lymphangiogenesis http://purl.obolibrary.org/obo/GO_1901490 regulation of lymphangiogenesis Any process that stops, prevents or reduces the frequency, rate or extent of lymphangiogenesis. http://purl.obolibrary.org/obo/GO_0051140 regulation of NK T cell proliferation http://purl.obolibrary.org/obo/GO_0051133 regulation of NK T cell activation Any process that modulates the frequency, rate or extent of natural killer T cell proliferation. http://purl.obolibrary.org/obo/GO_1901492 positive regulation of lymphangiogenesis http://purl.obolibrary.org/obo/GO_1901490 regulation of lymphangiogenesis Any process that activates or increases the frequency, rate or extent of lymphangiogenesis. http://purl.obolibrary.org/obo/GO_0051141 negative regulation of NK T cell proliferation http://purl.obolibrary.org/obo/GO_0051140 regulation of NK T cell proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer T cell proliferation. http://purl.obolibrary.org/obo/GO_1901509 regulation of endothelial tube morphogenesis http://purl.obolibrary.org/obo/GO_1905330 regulation of morphogenesis of an epithelium Any process that modulates the frequency, rate or extent of endothelial tube morphogenesis. http://purl.obolibrary.org/obo/GO_0051142 positive regulation of NK T cell proliferation http://purl.obolibrary.org/obo/GO_0051140 regulation of NK T cell proliferation Any process that activates or increases the frequency, rate or extent of natural killer T cell proliferation. http://purl.obolibrary.org/obo/GO_1901532 regulation of hematopoietic progenitor cell differentiation http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the frequency, rate or extent of hematopoietic progenitor cell differentiation. http://purl.obolibrary.org/obo/GO_0051150 regulation of smooth muscle cell differentiation http://purl.obolibrary.org/obo/GO_0051147 regulation of muscle cell differentiation Any process that modulates the frequency, rate or extent of smooth muscle cell differentiation. http://purl.obolibrary.org/obo/GO_1901533 negative regulation of hematopoietic progenitor cell differentiation http://purl.obolibrary.org/obo/GO_1901532 regulation of hematopoietic progenitor cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic progenitor cell differentiation. http://purl.obolibrary.org/obo/GO_1901534 positive regulation of hematopoietic progenitor cell differentiation http://purl.obolibrary.org/obo/GO_0045597 positive regulation of cell differentiation Any process that activates or increases the frequency, rate or extent of hematopoietic progenitor cell differentiation. http://purl.obolibrary.org/obo/GO_0051151 negative regulation of smooth muscle cell differentiation http://purl.obolibrary.org/obo/GO_0051148 negative regulation of muscle cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell differentiation. http://purl.obolibrary.org/obo/GO_1901550 regulation of endothelial cell development http://purl.obolibrary.org/obo/GO_0060284 regulation of cell development Any process that modulates the frequency, rate or extent of endothelial cell development. http://purl.obolibrary.org/obo/GO_0051152 positive regulation of smooth muscle cell differentiation http://purl.obolibrary.org/obo/GO_0051149 positive regulation of muscle cell differentiation Any process that activates or increases the frequency, rate or extent of smooth muscle cell differentiation. http://purl.obolibrary.org/obo/GO_0051236 establishment of RNA localization http://purl.obolibrary.org/obo/GO_0051234 establishment of localization The directed movement of RNA to a specific location. http://purl.obolibrary.org/obo/GO_0051355 proprioception involved in equilibrioception http://purl.obolibrary.org/obo/GO_0019230 proprioception The series of events contributing to equilibrioception by which an organism senses the position, location, orientation, and movement of the body and its parts. Proprioception plays an important role in the ability of an organism to perceive its orientation with respect to gravity. http://purl.obolibrary.org/obo/GO_0051379 epinephrine binding http://purl.obolibrary.org/obo/GO_0043169 cation binding Binding to epinephrine, a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine. http://purl.obolibrary.org/obo/GO_1901551 negative regulation of endothelial cell development http://purl.obolibrary.org/obo/GO_0010721 negative regulation of cell development Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell development. http://purl.obolibrary.org/obo/GO_0051380 norepinephrine binding http://purl.obolibrary.org/obo/GO_0043169 cation binding Binding to norepinephrine, (3,4-dihydroxyphenyl-2-aminoethanol), a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine. http://purl.obolibrary.org/obo/GO_1901552 positive regulation of endothelial cell development http://purl.obolibrary.org/obo/GO_0010720 positive regulation of cell development Any process that activates or increases the frequency, rate or extent of endothelial cell development. http://purl.obolibrary.org/obo/GO_0051384 response to glucocorticoid http://purl.obolibrary.org/obo/GO_0031960 response to corticosteroid Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucocorticoid stimulus. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects. http://purl.obolibrary.org/obo/GO_1901588 dendritic microtubule http://purl.obolibrary.org/obo/GO_0005874 microtubule Any microtubule in a dendrite, a neuron projection. http://purl.obolibrary.org/obo/GO_0051385 response to mineralocorticoid http://purl.obolibrary.org/obo/GO_0031960 response to corticosteroid Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mineralocorticoid stimulus. Mineralocorticoids are hormonal C21 corticosteroids synthesized from cholesterol and characterized by their similarity to aldosterone. Mineralocorticoids act primarily on water and electrolyte balance. http://purl.obolibrary.org/obo/GO_1901589 axon microtubule bundle http://purl.obolibrary.org/obo/GO_0097427 microtubule bundle An arrangement of closely apposed microtubules running parallel to each other in the axon hillock and initial segment. http://purl.obolibrary.org/obo/GO_0051410 detoxification of nitrogen compound http://purl.obolibrary.org/obo/GO_0098754 detoxification Any process that reduces or removes the toxicity of nitrogenous compounds which are dangerous or toxic. This includes the aerobic conversion of toxic compounds to harmless substances. http://purl.obolibrary.org/obo/GO_1901608 regulation of vesicle transport along microtubule http://purl.obolibrary.org/obo/GO_1902513 regulation of organelle transport along microtubule Any process that modulates the frequency, rate or extent of vesicle transport along microtubule. http://purl.obolibrary.org/obo/GO_0051457 maintenance of protein location in nucleus http://purl.obolibrary.org/obo/GO_0072595 maintenance of protein localization in organelle Any process in which a protein is maintained in the nucleus and prevented from moving elsewhere. These include sequestration within the nucleus, protein stabilization to prevent transport elsewhere and the active retrieval of proteins that escape the nucleus. http://purl.obolibrary.org/obo/GO_1901609 negative regulation of vesicle transport along microtubule http://purl.obolibrary.org/obo/GO_1901608 regulation of vesicle transport along microtubule Any process that stops, prevents or reduces the frequency, rate or extent of vesicle transport along microtubule. http://purl.obolibrary.org/obo/GO_0051458 corticotropin secretion http://purl.obolibrary.org/obo/GO_0060986 endocrine hormone secretion The regulated release of corticotropin by a cell. Corticotropin hormone is a polypeptide hormone synthesized and secreted from corticotropes in the anterior lobe of the pituitary gland in response to corticotropin-releasing hormone (CRH) released by the hypothalamus. http://purl.obolibrary.org/obo/GO_1901610 positive regulation of vesicle transport along microtubule http://purl.obolibrary.org/obo/GO_1901608 regulation of vesicle transport along microtubule Any process that activates or increases the frequency, rate or extent of vesicle transport along microtubule. http://purl.obolibrary.org/obo/GO_0051459 regulation of corticotropin secretion http://purl.obolibrary.org/obo/GO_0090276 regulation of peptide hormone secretion Any process that modulates the frequency, rate or extent of the regulated release of corticotropic hormone from a cell. http://purl.obolibrary.org/obo/GO_1901613 negative regulation of terminal button organization http://purl.obolibrary.org/obo/GO_0051129 negative regulation of cellular component organization Any process that stops, prevents or reduces the frequency, rate or extent of terminal button organization. http://purl.obolibrary.org/obo/GO_0051460 negative regulation of corticotropin secretion http://purl.obolibrary.org/obo/GO_0051241 negative regulation of multicellular organismal process Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of corticotropic hormone from a cell. http://purl.obolibrary.org/obo/GO_1901614 positive regulation of terminal button organization http://purl.obolibrary.org/obo/GO_0051130 positive regulation of cellular component organization Any process that activates or increases the frequency, rate or extent of terminal button organization. http://purl.obolibrary.org/obo/GO_0051461 positive regulation of corticotropin secretion http://purl.obolibrary.org/obo/GO_0090277 positive regulation of peptide hormone secretion Any process that activates or increases the frequency, rate or extent of the regulated release of corticotropin hormone from a cell. http://purl.obolibrary.org/obo/GO_1901624 negative regulation of lymphocyte chemotaxis http://purl.obolibrary.org/obo/GO_1901623 regulation of lymphocyte chemotaxis Any process that stops, prevents or reduces the frequency, rate or extent of lymphocyte chemotaxis. http://purl.obolibrary.org/obo/GO_0051546 keratinocyte migration http://purl.obolibrary.org/obo/GO_0010631 epithelial cell migration The directed movement of a keratinocyte, epidermal cells which synthesize keratin, from one site to another. http://purl.obolibrary.org/obo/GO_1901626 regulation of postsynaptic membrane organization http://purl.obolibrary.org/obo/GO_0051128 regulation of cellular component organization Any process that modulates the frequency, rate or extent of postsynaptic membrane organization. http://purl.obolibrary.org/obo/GO_0051547 regulation of keratinocyte migration http://purl.obolibrary.org/obo/GO_0010632 regulation of epithelial cell migration Any process that modulates the frequency, rate or extent of keratinocyte migration. http://purl.obolibrary.org/obo/GO_1901627 negative regulation of postsynaptic membrane organization http://purl.obolibrary.org/obo/GO_1905809 negative regulation of synapse organization Any process that stops, prevents or reduces the frequency, rate or extent of postsynaptic membrane organization. http://purl.obolibrary.org/obo/GO_0051548 negative regulation of keratinocyte migration http://purl.obolibrary.org/obo/GO_0010633 negative regulation of epithelial cell migration Any process that stops, prevents, or reduces the frequency, rate or extent of keratinocyte migration. http://purl.obolibrary.org/obo/GO_1901628 positive regulation of postsynaptic membrane organization http://purl.obolibrary.org/obo/GO_0051130 positive regulation of cellular component organization Any process that activates or increases the frequency, rate or extent of postsynaptic membrane organization. http://purl.obolibrary.org/obo/GO_0051549 positive regulation of keratinocyte migration http://purl.obolibrary.org/obo/GO_0010634 positive regulation of epithelial cell migration Any process that activates or increases the frequency, rate or extent of keratinocyte migration. http://purl.obolibrary.org/obo/GO_0051560 mitochondrial calcium ion homeostasis http://purl.obolibrary.org/obo/GO_0006874 intracellular calcium ion homeostasis Any process involved in the maintenance of an internal steady state of calcium ions within the cytoplasm of a cell or between mitochondria and their surroundings. http://purl.obolibrary.org/obo/GO_1901645 regulation of synoviocyte proliferation http://purl.obolibrary.org/obo/GO_0050678 regulation of epithelial cell proliferation Any process that modulates the frequency, rate or extent of synoviocyte proliferation. http://purl.obolibrary.org/obo/GO_0051580 regulation of neurotransmitter uptake http://purl.obolibrary.org/obo/GO_0051588 regulation of neurotransmitter transport Any process that modulates the frequency, rate or extent of the directed movement of a neurotransmitter into a neuron or glial cell. http://purl.obolibrary.org/obo/GO_1901646 negative regulation of synoviocyte proliferation http://purl.obolibrary.org/obo/GO_1901645 regulation of synoviocyte proliferation Any process that stops, prevents or reduces the frequency, rate or extent of synoviocyte proliferation. http://purl.obolibrary.org/obo/GO_0051581 negative regulation of neurotransmitter uptake http://purl.obolibrary.org/obo/GO_0051589 negative regulation of neurotransmitter transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a neurotransmitter into a neuron or glial cell. http://purl.obolibrary.org/obo/GO_1901647 positive regulation of synoviocyte proliferation http://purl.obolibrary.org/obo/GO_1901645 regulation of synoviocyte proliferation Any process that activates or increases the frequency, rate or extent of synoviocyte proliferation. http://purl.obolibrary.org/obo/GO_0051582 positive regulation of neurotransmitter uptake http://purl.obolibrary.org/obo/GO_0051590 positive regulation of neurotransmitter transport Any process that activates or increases the frequency, rate or extent of the directed movement of a neurotransmitter into a neuron or glial cell. http://purl.obolibrary.org/obo/GO_0051588 regulation of neurotransmitter transport http://purl.obolibrary.org/obo/GO_0051049 regulation of transport Any process that modulates the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_1901691 proton binding http://purl.obolibrary.org/obo/GO_0043169 cation binding Binding to proton. http://purl.obolibrary.org/obo/GO_0051589 negative regulation of neurotransmitter transport http://purl.obolibrary.org/obo/GO_0051051 negative regulation of transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_1901692 regulation of compound eye retinal cell apoptotic process http://purl.obolibrary.org/obo/GO_0042981 regulation of apoptotic process Any process that modulates the frequency, rate or extent of compound eye retinal cell apoptotic process. http://purl.obolibrary.org/obo/GO_0051615 histamine uptake http://purl.obolibrary.org/obo/GO_0051608 histamine transport The directed movement of histamine into a cell, typically presynaptic neurons or glial cells. Histamine is a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans. http://purl.obolibrary.org/obo/GO_1901693 negative regulation of compound eye retinal cell apoptotic process http://purl.obolibrary.org/obo/GO_1901692 regulation of compound eye retinal cell apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of compound eye retinal cell apoptotic process. http://purl.obolibrary.org/obo/GO_0051616 regulation of histamine uptake http://purl.obolibrary.org/obo/GO_0051580 regulation of neurotransmitter uptake Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter histamine into a cell. http://purl.obolibrary.org/obo/GO_1901706 mesenchymal cell differentiation involved in bone development http://purl.obolibrary.org/obo/GO_0048762 mesenchymal cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of bone as it progresses from its formation to the mature state. http://purl.obolibrary.org/obo/GO_0051617 negative regulation of histamine uptake http://purl.obolibrary.org/obo/GO_0051616 regulation of histamine uptake Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of histamine into a cell. http://purl.obolibrary.org/obo/GO_1901715 regulation of gamma-aminobutyric acid catabolic process http://purl.obolibrary.org/obo/GO_0009894 regulation of catabolic process Any process that modulates the frequency, rate or extent of gamma-aminobutyric acid catabolic process. http://purl.obolibrary.org/obo/GO_0051618 positive regulation of histamine uptake http://purl.obolibrary.org/obo/GO_0051616 regulation of histamine uptake Any process that activates or increases the frequency, rate or extent of the directed movement of histamine into a cell. http://purl.obolibrary.org/obo/GO_1901716 negative regulation of gamma-aminobutyric acid catabolic process http://purl.obolibrary.org/obo/GO_0009895 negative regulation of catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of gamma-aminobutyric acid catabolic process. http://purl.obolibrary.org/obo/GO_0051620 norepinephrine uptake http://purl.obolibrary.org/obo/GO_0015874 norepinephrine transport The directed movement of norepinephrine into a cell, typically presynaptic neurons or glial cells. Norepinephrine (3,4-dihydroxyphenyl-2-aminoethanol) is a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine. http://purl.obolibrary.org/obo/GO_1901717 positive regulation of gamma-aminobutyric acid catabolic process http://purl.obolibrary.org/obo/GO_0009896 positive regulation of catabolic process Any process that activates or increases the frequency, rate or extent of gamma-aminobutyric acid catabolic process. http://purl.obolibrary.org/obo/GO_0051621 regulation of norepinephrine uptake http://purl.obolibrary.org/obo/GO_0051049 regulation of transport Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter norepinephrine into a cell. http://purl.obolibrary.org/obo/GO_1901826 zeaxanthin catabolic process http://purl.obolibrary.org/obo/GO_0016124 xanthophyll catabolic process The chemical reactions and pathways resulting in the breakdown of zeaxanthin. http://purl.obolibrary.org/obo/GO_0051622 negative regulation of norepinephrine uptake http://purl.obolibrary.org/obo/GO_0051051 negative regulation of transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of norepinephrine into a cell. http://purl.obolibrary.org/obo/GO_1901827 zeaxanthin biosynthetic process http://purl.obolibrary.org/obo/GO_0016123 xanthophyll biosynthetic process The chemical reactions and pathways resulting in the formation of zeaxanthin. http://purl.obolibrary.org/obo/GO_0051623 positive regulation of norepinephrine uptake http://purl.obolibrary.org/obo/GO_0051050 positive regulation of transport Any process that activates or increases the frequency, rate or extent of the directed movement of norepinephrine into a cell. http://purl.obolibrary.org/obo/GO_1901876 regulation of calcium ion binding http://purl.obolibrary.org/obo/GO_0051098 regulation of binding Any process that modulates the frequency, rate or extent of calcium ion binding. http://purl.obolibrary.org/obo/GO_0051630 acetylcholine uptake http://purl.obolibrary.org/obo/GO_0015870 acetylcholine transport The directed movement of acetylcholine into a cell, typically presynaptic neurons or glial cells. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues. http://purl.obolibrary.org/obo/GO_0051631 regulation of acetylcholine uptake http://purl.obolibrary.org/obo/GO_0051952 regulation of amine transport Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter acetylcholine into a cell. http://purl.obolibrary.org/obo/GO_1901951 regulation of anterograde dense core granule transport http://purl.obolibrary.org/obo/GO_1904809 regulation of dense core granule transport Any process that modulates the frequency, rate or extent of anterograde dense core granule transport. http://purl.obolibrary.org/obo/GO_0051632 negative regulation of acetylcholine uptake http://purl.obolibrary.org/obo/GO_0051953 negative regulation of amine transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of acetylcholine into a cell. http://purl.obolibrary.org/obo/GO_0051633 positive regulation of acetylcholine uptake http://purl.obolibrary.org/obo/GO_0051954 positive regulation of amine transport Any process that activates or increases the frequency, rate or extent of the directed movement of acetylcholine into a cell. http://purl.obolibrary.org/obo/GO_1901952 negative regulation of anterograde dense core granule transport http://purl.obolibrary.org/obo/GO_1904810 negative regulation of dense core granule transport Any process that stops, prevents or reduces the frequency, rate or extent of anterograde dense core granule transport. http://purl.obolibrary.org/obo/GO_0051641 cellular localization http://purl.obolibrary.org/obo/GO_0051179 localization A cellular localization process whereby a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a cell including the localization of substances or cellular entities to the cell membrane. http://purl.obolibrary.org/obo/GO_0051645 Golgi localization http://purl.obolibrary.org/obo/GO_0051640 organelle localization Any process in which the Golgi is transported to, and/or maintained in, a specific location within the cell. http://purl.obolibrary.org/obo/GO_1901953 positive regulation of anterograde dense core granule transport http://purl.obolibrary.org/obo/GO_1904811 positive regulation of dense core granule transport Any process that activates or increases the frequency, rate or extent of anterograde dense core granule transport. http://purl.obolibrary.org/obo/GO_0051646 mitochondrion localization http://purl.obolibrary.org/obo/GO_0051640 organelle localization Any process in which a mitochondrion or mitochondria are transported to, and/or maintained in, a specific location within the cell. http://purl.obolibrary.org/obo/GO_1901954 regulation of retrograde dense core granule transport http://purl.obolibrary.org/obo/GO_2001017 regulation of retrograde axon cargo transport Any process that modulates the frequency, rate or extent of retrograde dense core granule transport. http://purl.obolibrary.org/obo/GO_0051657 maintenance of organelle location http://purl.obolibrary.org/obo/GO_0051651 maintenance of location in cell Any process in which an organelle is maintained in a specific location within a cell and prevented from moving elsewhere. http://purl.obolibrary.org/obo/GO_1901955 negative regulation of retrograde dense core granule transport http://purl.obolibrary.org/obo/GO_2001018 negative regulation of retrograde axon cargo transport Any process that stops, prevents or reduces the frequency, rate or extent of retrograde dense core granule transport. http://purl.obolibrary.org/obo/GO_0051659 maintenance of mitochondrion location http://purl.obolibrary.org/obo/GO_0051657 maintenance of organelle location Any process in which a mitochondrion is maintained in a specific location within a cell and prevented from moving elsewhere. http://purl.obolibrary.org/obo/GO_1901956 positive regulation of retrograde dense core granule transport http://purl.obolibrary.org/obo/GO_2001019 positive regulation of retrograde axon cargo transport Any process that activates or increases the frequency, rate or extent of retrograde dense core granule transport. http://purl.obolibrary.org/obo/GO_0051683 establishment of Golgi localization http://purl.obolibrary.org/obo/GO_0051656 establishment of organelle localization The directed movement of the Golgi to a specific location. http://purl.obolibrary.org/obo/GO_1902018 negative regulation of cilium assembly http://purl.obolibrary.org/obo/GO_0120033 negative regulation of plasma membrane bounded cell projection assembly Any process that stops, prevents or reduces the frequency, rate or extent of cilium assembly. http://purl.obolibrary.org/obo/GO_0051684 maintenance of Golgi location http://purl.obolibrary.org/obo/GO_0051657 maintenance of organelle location Any process in which the Golgi is maintained in a specific location within a cell and prevented from moving elsewhere. http://purl.obolibrary.org/obo/GO_0051688 maintenance of plastid location http://purl.obolibrary.org/obo/GO_0051644 plastid localization Any process in which a plastid is maintained in a specific location within a cell and prevented from moving elsewhere. http://purl.obolibrary.org/obo/GO_1902020 negative regulation of cilium-dependent cell motility http://purl.obolibrary.org/obo/GO_1902019 regulation of cilium-dependent cell motility Any process that stops, prevents or reduces the frequency, rate or extent of cilium-dependent cell motility. http://purl.obolibrary.org/obo/GO_0051738 xanthophyll binding http://purl.obolibrary.org/obo/GO_0031409 pigment binding Binding to xanthophylls, any of several neutral yellow to orange carotenoid pigments containing oxygen. http://purl.obolibrary.org/obo/GO_1902033 regulation of hematopoietic stem cell proliferation http://purl.obolibrary.org/obo/GO_0072091 regulation of stem cell proliferation Any process that modulates the frequency, rate or extent of hematopoietic stem cell proliferation. http://purl.obolibrary.org/obo/GO_1902034 negative regulation of hematopoietic stem cell proliferation http://purl.obolibrary.org/obo/GO_1902033 regulation of hematopoietic stem cell proliferation Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic stem cell proliferation. http://purl.obolibrary.org/obo/GO_0051784 negative regulation of nuclear division http://purl.obolibrary.org/obo/GO_0010639 negative regulation of organelle organization Any process that stops, prevents, or reduces the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information. http://purl.obolibrary.org/obo/GO_1902035 positive regulation of hematopoietic stem cell proliferation http://purl.obolibrary.org/obo/GO_1902033 regulation of hematopoietic stem cell proliferation Any process that activates or increases the frequency, rate or extent of hematopoietic stem cell proliferation. http://purl.obolibrary.org/obo/GO_0051785 positive regulation of nuclear division http://purl.obolibrary.org/obo/GO_0010638 positive regulation of organelle organization Any process that activates or increases the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information. http://purl.obolibrary.org/obo/GO_1902036 regulation of hematopoietic stem cell differentiation http://purl.obolibrary.org/obo/GO_1901532 regulation of hematopoietic progenitor cell differentiation Any process that modulates the frequency, rate or extent of hematopoietic stem cell differentiation. http://purl.obolibrary.org/obo/GO_0051797 regulation of hair follicle development http://purl.obolibrary.org/obo/GO_0042634 regulation of hair cycle Any process that modulates the frequency, rate or extent of hair follicle development. http://purl.obolibrary.org/obo/GO_1902037 negative regulation of hematopoietic stem cell differentiation http://purl.obolibrary.org/obo/GO_1902036 regulation of hematopoietic stem cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic stem cell differentiation. http://purl.obolibrary.org/obo/GO_0051798 positive regulation of hair follicle development http://purl.obolibrary.org/obo/GO_0051240 positive regulation of multicellular organismal process Any process that activates or increases the frequency, rate or extent of hair follicle development. http://purl.obolibrary.org/obo/GO_1902038 positive regulation of hematopoietic stem cell differentiation http://purl.obolibrary.org/obo/GO_1902036 regulation of hematopoietic stem cell differentiation Any process that activates or increases the frequency, rate or extent of hematopoietic stem cell differentiation. http://purl.obolibrary.org/obo/GO_0051799 negative regulation of hair follicle development http://purl.obolibrary.org/obo/GO_0051241 negative regulation of multicellular organismal process Any process that stops, prevents, or reduces the frequency, rate or extent of hair follicle development. http://purl.obolibrary.org/obo/GO_1902065 response to L-glutamate http://purl.obolibrary.org/obo/GO_1901698 response to nitrogen compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an L-glutamate stimulus. http://purl.obolibrary.org/obo/GO_0051882 mitochondrial depolarization http://purl.obolibrary.org/obo/GO_0051881 regulation of mitochondrial membrane potential The process in which the potential difference across the mitochondrial membrane is reduced from its steady state level. http://purl.obolibrary.org/obo/GO_1902076 regulation of lateral motor column neuron migration http://purl.obolibrary.org/obo/GO_1905483 regulation of motor neuron migration Any process that modulates the frequency, rate or extent of lateral motor column neuron migration. http://purl.obolibrary.org/obo/GO_0051891 positive regulation of cardioblast differentiation http://purl.obolibrary.org/obo/GO_0051890 regulation of cardioblast differentiation Any process that activates or increases the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. http://purl.obolibrary.org/obo/GO_1902077 negative regulation of lateral motor column neuron migration http://purl.obolibrary.org/obo/GO_1905484 negative regulation of motor neuron migration Any process that stops, prevents or reduces the frequency, rate or extent of lateral motor column neuron migration. http://purl.obolibrary.org/obo/GO_0051900 regulation of mitochondrial depolarization http://purl.obolibrary.org/obo/GO_0051881 regulation of mitochondrial membrane potential Any process that modulates the frequency, rate or extent of the change in the membrane potential of the mitochondria from negative to positive. http://purl.obolibrary.org/obo/GO_1902078 positive regulation of lateral motor column neuron migration http://purl.obolibrary.org/obo/GO_1905485 positive regulation of motor neuron migration Any process that activates or increases the frequency, rate or extent of lateral motor column neuron migration. http://purl.obolibrary.org/obo/GO_0051901 positive regulation of mitochondrial depolarization http://purl.obolibrary.org/obo/GO_1904181 positive regulation of membrane depolarization Any process that activates, maintains or increases the frequency, rate or extent of the change in the membrane potential of the mitochondria from negative to positive. http://purl.obolibrary.org/obo/GO_1902172 regulation of keratinocyte apoptotic process http://purl.obolibrary.org/obo/GO_1904035 regulation of epithelial cell apoptotic process Any process that modulates the frequency, rate or extent of keratinocyte apoptotic process. http://purl.obolibrary.org/obo/GO_0051902 negative regulation of mitochondrial depolarization http://purl.obolibrary.org/obo/GO_1904180 negative regulation of membrane depolarization Any process that stops, prevents, or reduces the frequency, rate or extent of the change in the membrane potential of the mitochondria from negative to positive. http://purl.obolibrary.org/obo/GO_1902173 negative regulation of keratinocyte apoptotic process http://purl.obolibrary.org/obo/GO_1904036 negative regulation of epithelial cell apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of keratinocyte apoptotic process. http://purl.obolibrary.org/obo/GO_0051931 regulation of sensory perception http://purl.obolibrary.org/obo/GO_0031644 regulation of nervous system process Any process that modulates the frequency, rate or extent of sensory perception, the series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal. http://purl.obolibrary.org/obo/GO_1902174 positive regulation of keratinocyte apoptotic process http://purl.obolibrary.org/obo/GO_1904037 positive regulation of epithelial cell apoptotic process Any process that activates or increases the frequency, rate or extent of keratinocyte apoptotic process. http://purl.obolibrary.org/obo/GO_0051939 gamma-aminobutyric acid import http://purl.obolibrary.org/obo/GO_0015812 gamma-aminobutyric acid transport The directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate) into a cell or organelle. http://purl.obolibrary.org/obo/GO_1902211 regulation of prolactin signaling pathway http://purl.obolibrary.org/obo/GO_0001959 regulation of cytokine-mediated signaling pathway Any process that modulates the frequency, rate or extent of prolactin signaling pathway. http://purl.obolibrary.org/obo/GO_0051964 negative regulation of synapse assembly http://purl.obolibrary.org/obo/GO_1905809 negative regulation of synapse organization Any process that stops, prevents, or reduces the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse. http://purl.obolibrary.org/obo/GO_1902212 negative regulation of prolactin signaling pathway http://purl.obolibrary.org/obo/GO_1902211 regulation of prolactin signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of prolactin signaling pathway. http://purl.obolibrary.org/obo/GO_0051965 positive regulation of synapse assembly http://purl.obolibrary.org/obo/GO_0051963 regulation of synapse assembly Any process that activates, maintains or increases the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse. http://purl.obolibrary.org/obo/GO_1902213 positive regulation of prolactin signaling pathway http://purl.obolibrary.org/obo/GO_1902211 regulation of prolactin signaling pathway Any process that activates or increases the frequency, rate or extent of prolactin signaling pathway. http://purl.obolibrary.org/obo/GO_0051984 positive regulation of chromosome segregation http://purl.obolibrary.org/obo/GO_0090068 positive regulation of cell cycle process Any process that activates or increases the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets. http://purl.obolibrary.org/obo/GO_1902217 erythrocyte apoptotic process http://purl.obolibrary.org/obo/GO_0033028 myeloid cell apoptotic process Any apoptotic process in an erythrocyte. http://purl.obolibrary.org/obo/GO_0055013 cardiac muscle cell development http://purl.obolibrary.org/obo/GO_0055006 cardiac cell development The process whose specific outcome is the progression of a cardiac muscle cell over time, from its formation to the mature state. http://purl.obolibrary.org/obo/GO_1902250 regulation of erythrocyte apoptotic process http://purl.obolibrary.org/obo/GO_0033032 regulation of myeloid cell apoptotic process Any process that modulates the frequency, rate or extent of erythrocyte apoptotic process. http://purl.obolibrary.org/obo/GO_0060282 positive regulation of oocyte development http://purl.obolibrary.org/obo/GO_2000243 positive regulation of reproductive process Any process that increases the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell. http://purl.obolibrary.org/obo/GO_1902251 negative regulation of erythrocyte apoptotic process http://purl.obolibrary.org/obo/GO_1902250 regulation of erythrocyte apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of erythrocyte apoptotic process. http://purl.obolibrary.org/obo/GO_0060283 negative regulation of oocyte development http://purl.obolibrary.org/obo/GO_2000242 negative regulation of reproductive process Any process that decreases the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell. http://purl.obolibrary.org/obo/GO_1902252 positive regulation of erythrocyte apoptotic process http://purl.obolibrary.org/obo/GO_1902250 regulation of erythrocyte apoptotic process Any process that activates or increases the frequency, rate or extent of erythrocyte apoptotic process. http://purl.obolibrary.org/obo/GO_0060456 positive regulation of digestive system process http://purl.obolibrary.org/obo/GO_0044058 regulation of digestive system process Any process that increases the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism. http://purl.obolibrary.org/obo/GO_1902256 regulation of apoptotic process involved in outflow tract morphogenesis http://purl.obolibrary.org/obo/GO_1904748 regulation of apoptotic process involved in development Any process that modulates the frequency, rate or extent of apoptotic process involved in outflow tract morphogenesis. http://purl.obolibrary.org/obo/GO_0060872 semicircular canal development http://purl.obolibrary.org/obo/GO_0035295 tube development The progression of the semicircular canal from its initial formation to the mature structure. http://purl.obolibrary.org/obo/GO_1902257 negative regulation of apoptotic process involved in outflow tract morphogenesis http://purl.obolibrary.org/obo/GO_1902338 negative regulation of apoptotic process involved in morphogenesis Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in outflow tract morphogenesis. http://purl.obolibrary.org/obo/GO_0061138 morphogenesis of a branching epithelium http://purl.obolibrary.org/obo/GO_0002009 morphogenesis of an epithelium The process in which the anatomical structures of a branched epithelium are generated and organized. http://purl.obolibrary.org/obo/GO_1902262 apoptotic process involved in blood vessel morphogenesis http://purl.obolibrary.org/obo/GO_0060561 apoptotic process involved in morphogenesis Any apoptotic process that is involved in blood vessel morphogenesis. http://purl.obolibrary.org/obo/GO_0061550 cranial ganglion development http://purl.obolibrary.org/obo/GO_0061548 ganglion development The process whose specific outcome is the progression of a cranial ganglion over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization http://purl.obolibrary.org/obo/GO_0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of a ventricular cardiomyocyte contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. http://purl.obolibrary.org/obo/GO_0061572 actin filament bundle organization http://purl.obolibrary.org/obo/GO_0007015 actin filament organization A process that results in the assembly, arrangement of constituent parts, or disassembly of an actin filament bundle. http://purl.obolibrary.org/obo/GO_1902305 regulation of sodium ion transmembrane transport http://purl.obolibrary.org/obo/GO_1904062 regulation of monoatomic cation transmembrane transport Any process that modulates the frequency, rate or extent of sodium ion transmembrane transport. http://purl.obolibrary.org/obo/GO_0061842 microtubule organizing center localization http://purl.obolibrary.org/obo/GO_0051179 localization Any process in which the microtubule organizing center is transported to, and/or maintained in, a specific location within the cell. http://purl.obolibrary.org/obo/GO_1902306 negative regulation of sodium ion transmembrane transport http://purl.obolibrary.org/obo/GO_0010766 negative regulation of sodium ion transport Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion transmembrane transport. http://purl.obolibrary.org/obo/GO_0065007 biological regulation http://purl.obolibrary.org/obo/GO_0008150 biological_process Any process that modulates a measurable attribute of any biological process, quality or function. http://purl.obolibrary.org/obo/GO_1902307 positive regulation of sodium ion transmembrane transport http://purl.obolibrary.org/obo/GO_0010765 positive regulation of sodium ion transport Any process that activates or increases the frequency, rate or extent of sodium ion transmembrane transport. http://purl.obolibrary.org/obo/GO_0070201 regulation of establishment of protein localization http://purl.obolibrary.org/obo/GO_0032880 regulation of protein localization Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location. http://purl.obolibrary.org/obo/GO_1902340 negative regulation of chromosome condensation http://purl.obolibrary.org/obo/GO_0060623 regulation of chromosome condensation Any process that stops, prevents or reduces the frequency, rate or extent of chromosome condensation. http://purl.obolibrary.org/obo/GO_0070585 protein localization to mitochondrion http://purl.obolibrary.org/obo/GO_0033365 protein localization to organelle A process in which a protein is transported to, or maintained in, a location within the mitochondrion. http://purl.obolibrary.org/obo/GO_1902362 melanocyte apoptotic process http://purl.obolibrary.org/obo/GO_0006915 apoptotic process Any apoptotic process in a melanocyte, the main structural component of the epidermis. http://purl.obolibrary.org/obo/GO_0072676 lymphocyte migration http://purl.obolibrary.org/obo/GO_0071674 mononuclear cell migration The movement of a lymphocyte within or between different tissues and organs of the body. http://purl.obolibrary.org/obo/GO_1902396 protein localization to bicellular tight junction http://purl.obolibrary.org/obo/GO_0150105 protein localization to cell-cell junction A process in which a protein is transported to, or maintained in, a location within a bicellular tight junction. http://purl.obolibrary.org/obo/GO_0072677 eosinophil migration http://purl.obolibrary.org/obo/GO_0097530 granulocyte migration The movement of an eosinophil within or between different tissues and organs of the body. http://purl.obolibrary.org/obo/GO_1902427 regulation of water channel activity http://purl.obolibrary.org/obo/GO_0022898 regulation of transmembrane transporter activity Any process that modulates the frequency, rate or extent of water channel activity. http://purl.obolibrary.org/obo/GO_0090109 regulation of cell-substrate junction assembly http://purl.obolibrary.org/obo/GO_0150116 regulation of cell-substrate junction organization Any process that modulates the rate, frequency, or extent of cell-substrate junction assembly. Cell-substrate junction assembly is the aggregation, arrangement and bonding together of a set of components to form a junction between a cell and its substrate. http://purl.obolibrary.org/obo/GO_1902455 negative regulation of stem cell population maintenance http://purl.obolibrary.org/obo/GO_2000036 regulation of stem cell population maintenance Any process that stops, prevents or reduces the frequency, rate or extent of stem cell population maintenance. http://purl.obolibrary.org/obo/GO_0090278 negative regulation of peptide hormone secretion http://purl.obolibrary.org/obo/GO_0090276 regulation of peptide hormone secretion Any process that decreases the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules. http://purl.obolibrary.org/obo/GO_1902459 positive regulation of stem cell population maintenance http://purl.obolibrary.org/obo/GO_2000036 regulation of stem cell population maintenance Any process that activates or increases the frequency, rate or extent of stem cell population maintenance. http://purl.obolibrary.org/obo/GO_0090279 regulation of calcium ion import http://purl.obolibrary.org/obo/GO_0051924 regulation of calcium ion transport Any process that modulates the rate, frequency, or extent of the directed movement of calcium ions into a cell or organelle. http://purl.obolibrary.org/obo/GO_0090280 positive regulation of calcium ion import http://purl.obolibrary.org/obo/GO_0051928 positive regulation of calcium ion transport Any process that increases the rate, frequency, or extent of the directed movement of calcium ions into a cell or organelle. http://purl.obolibrary.org/obo/GO_0090281 negative regulation of calcium ion import http://purl.obolibrary.org/obo/GO_0051926 negative regulation of calcium ion transport Any process that decreases the rate, frequency, or extent of the directed movement of calcium ions into a cell or organelle. http://purl.obolibrary.org/obo/GO_1902463 protein localization to cell leading edge http://purl.obolibrary.org/obo/GO_0008104 intracellular protein localization A process in which a protein is transported to, or maintained in, a location within a cell leading edge. http://purl.obolibrary.org/obo/GO_0090493 catecholamine uptake http://purl.obolibrary.org/obo/GO_0051937 catecholamine transport The directed movement of catecholamine into a cell. http://purl.obolibrary.org/obo/GO_1902473 regulation of protein localization to synapse http://purl.obolibrary.org/obo/GO_0032880 regulation of protein localization Any process that modulates the frequency, rate or extent of protein localization to synapse. http://purl.obolibrary.org/obo/GO_0090494 dopamine uptake http://purl.obolibrary.org/obo/GO_0015872 dopamine transport The directed movement of dopamine into a cell. http://purl.obolibrary.org/obo/GO_1902474 positive regulation of protein localization to synapse http://purl.obolibrary.org/obo/GO_1902473 regulation of protein localization to synapse Any process that activates or increases the frequency, rate or extent of protein localization to synapse. http://purl.obolibrary.org/obo/GO_0097553 calcium ion transmembrane import into cytosol http://purl.obolibrary.org/obo/GO_0070588 calcium ion transmembrane transport A process in which a calcium ion is transported from one side of a membrane to the other into the cytosol by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_1902482 regulatory T cell apoptotic process http://purl.obolibrary.org/obo/GO_0070231 T cell apoptotic process Any apoptotic process in a regulatory T cell. http://purl.obolibrary.org/obo/GO_0098728 germline stem cell asymmetric division http://purl.obolibrary.org/obo/GO_0098722 asymmetric stem cell division The self-renewing division of a germline stem cell, to produce a daughter stem cell and a daughter germ cell which will divide to form one or more gametes. http://purl.obolibrary.org/obo/GO_1902484 Sertoli cell apoptotic process http://purl.obolibrary.org/obo/GO_1904019 epithelial cell apoptotic process Any apoptotic process in a Sertoli cell. http://purl.obolibrary.org/obo/GO_0099569 presynaptic cytoskeleton http://purl.obolibrary.org/obo/GO_0005856 cytoskeleton The portion of the cytoskeleton contained within the presynapse. http://purl.obolibrary.org/obo/GO_1902488 cholangiocyte apoptotic process http://purl.obolibrary.org/obo/GO_1904019 epithelial cell apoptotic process Any apoptotic process in a cholangiocyte. http://purl.obolibrary.org/obo/GO_1900006 positive regulation of dendrite development http://purl.obolibrary.org/obo/GO_0010976 positive regulation of neuron projection development Any process that activates or increases the frequency, rate or extent of dendrite development. http://purl.obolibrary.org/obo/GO_1902489 hepatoblast apoptotic process http://purl.obolibrary.org/obo/GO_0006915 apoptotic process Any apoptotic process in a hepatoblast. http://purl.obolibrary.org/obo/GO_1900076 regulation of cellular response to insulin stimulus http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of cellular response to insulin stimulus. http://purl.obolibrary.org/obo/GO_1902490 regulation of sperm capacitation http://purl.obolibrary.org/obo/GO_2000241 regulation of reproductive process Any process that modulates the frequency, rate or extent of sperm capacitation. http://purl.obolibrary.org/obo/GO_1900077 negative regulation of cellular response to insulin stimulus http://purl.obolibrary.org/obo/GO_0048585 negative regulation of response to stimulus Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to insulin stimulus. http://purl.obolibrary.org/obo/GO_1902491 negative regulation of sperm capacitation http://purl.obolibrary.org/obo/GO_2000242 negative regulation of reproductive process Any process that stops, prevents or reduces the frequency, rate or extent of sperm capacitation. http://purl.obolibrary.org/obo/GO_1900078 positive regulation of cellular response to insulin stimulus http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the frequency, rate or extent of cellular response to insulin stimulus. http://purl.obolibrary.org/obo/GO_1902492 positive regulation of sperm capacitation http://purl.obolibrary.org/obo/GO_2000243 positive regulation of reproductive process Any process that activates or increases the frequency, rate or extent of sperm capacitation. http://purl.obolibrary.org/obo/GO_1901694 positive regulation of compound eye retinal cell apoptotic process http://purl.obolibrary.org/obo/GO_0043065 positive regulation of apoptotic process Any process that activates or increases the frequency, rate or extent of compound eye retinal cell apoptotic process. http://purl.obolibrary.org/obo/GO_1902510 regulation of apoptotic DNA fragmentation http://purl.obolibrary.org/obo/GO_1903624 regulation of DNA catabolic process Any process that modulates the frequency, rate or extent of apoptotic DNA fragmentation. http://purl.obolibrary.org/obo/GO_1901862 negative regulation of muscle tissue development http://purl.obolibrary.org/obo/GO_1901861 regulation of muscle tissue development Any process that stops, prevents or reduces the frequency, rate or extent of muscle tissue development. http://purl.obolibrary.org/obo/GO_1902511 negative regulation of apoptotic DNA fragmentation http://purl.obolibrary.org/obo/GO_1903625 negative regulation of DNA catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic DNA fragmentation. http://purl.obolibrary.org/obo/GO_1901863 positive regulation of muscle tissue development http://purl.obolibrary.org/obo/GO_1901861 regulation of muscle tissue development Any process that activates or increases the frequency, rate or extent of muscle tissue development. http://purl.obolibrary.org/obo/GO_1902512 positive regulation of apoptotic DNA fragmentation http://purl.obolibrary.org/obo/GO_1903626 positive regulation of DNA catabolic process Any process that activates or increases the frequency, rate or extent of apoptotic DNA fragmentation. http://purl.obolibrary.org/obo/GO_1901889 negative regulation of cell junction assembly http://purl.obolibrary.org/obo/GO_0051129 negative regulation of cellular component organization Any process that stops, prevents or reduces the frequency, rate or extent of cell junction assembly. http://purl.obolibrary.org/obo/GO_1902513 regulation of organelle transport along microtubule http://purl.obolibrary.org/obo/GO_0032386 regulation of intracellular transport Any process that modulates the frequency, rate or extent of organelle transport along microtubule. http://purl.obolibrary.org/obo/GO_1901890 positive regulation of cell junction assembly http://purl.obolibrary.org/obo/GO_0051130 positive regulation of cellular component organization Any process that activates or increases the frequency, rate or extent of cell junction assembly. http://purl.obolibrary.org/obo/GO_1902570 protein localization to nucleolus http://purl.obolibrary.org/obo/GO_0034504 protein localization to nucleus A process in which a protein is transported to, or maintained in, a location within a nucleolus. http://purl.obolibrary.org/obo/GO_1902680 positive regulation of RNA biosynthetic process http://purl.obolibrary.org/obo/GO_2001141 regulation of RNA biosynthetic process Any process that activates or increases the frequency, rate or extent of RNA biosynthetic process. http://purl.obolibrary.org/obo/GO_1902584 positive regulation of response to water deprivation http://purl.obolibrary.org/obo/GO_2000070 regulation of response to water deprivation Any process that activates or increases the frequency, rate or extent of response to water deprivation. http://purl.obolibrary.org/obo/GO_1902876 negative regulation of embryonic pattern specification http://purl.obolibrary.org/obo/GO_0051241 negative regulation of multicellular organismal process Any process that stops, prevents or reduces the frequency, rate or extent of embryonic pattern specification. http://purl.obolibrary.org/obo/GO_1902683 regulation of receptor localization to synapse http://purl.obolibrary.org/obo/GO_0032879 regulation of localization Any process that modulates the frequency, rate or extent of receptor localization to synapse. http://purl.obolibrary.org/obo/GO_1902877 positive regulation of embryonic pattern specification http://purl.obolibrary.org/obo/GO_0051240 positive regulation of multicellular organismal process Any process that activates or increases the frequency, rate or extent of embryonic pattern specification. http://purl.obolibrary.org/obo/GO_1902684 negative regulation of receptor localization to synapse http://purl.obolibrary.org/obo/GO_1902683 regulation of receptor localization to synapse Any process that stops, prevents or reduces the frequency, rate or extent of receptor localization to synapse. http://purl.obolibrary.org/obo/GO_1903034 regulation of response to wounding http://purl.obolibrary.org/obo/GO_0080134 regulation of response to stress Any process that modulates the frequency, rate or extent of response to wounding. http://purl.obolibrary.org/obo/GO_1902685 positive regulation of receptor localization to synapse http://purl.obolibrary.org/obo/GO_1902683 regulation of receptor localization to synapse Any process that activates or increases the frequency, rate or extent of receptor localization to synapse. http://purl.obolibrary.org/obo/GO_1903035 negative regulation of response to wounding http://purl.obolibrary.org/obo/GO_0048585 negative regulation of response to stimulus Any process that stops, prevents or reduces the frequency, rate or extent of response to wounding. http://purl.obolibrary.org/obo/GO_1902691 respiratory basal cell differentiation http://purl.obolibrary.org/obo/GO_0048863 stem cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a respiratory basal cell. http://purl.obolibrary.org/obo/GO_1903036 positive regulation of response to wounding http://purl.obolibrary.org/obo/GO_0048584 positive regulation of response to stimulus Any process that activates or increases the frequency, rate or extent of response to wounding. http://purl.obolibrary.org/obo/GO_1903037 regulation of leukocyte cell-cell adhesion http://purl.obolibrary.org/obo/GO_0022407 regulation of cell-cell adhesion Any process that modulates the frequency, rate or extent of leukocyte cell-cell adhesion. http://purl.obolibrary.org/obo/GO_1902710 GABA receptor complex http://purl.obolibrary.org/obo/GO_0043235 receptor complex A protein complex which is capable of GABA receptor activity. Upon binding of gamma-aminobutyric acid (GABA) it transmits the signal from one side of the membrane to the other to initiate a change in cell activity. Major inhibitory receptor in vertebrate brain. Also found in other vertebrate tissues, invertebrates and possibly in plants. Effective benzodiazepine receptor. http://purl.obolibrary.org/obo/GO_1903038 negative regulation of leukocyte cell-cell adhesion http://purl.obolibrary.org/obo/GO_0022408 negative regulation of cell-cell adhesion Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte cell-cell adhesion. http://purl.obolibrary.org/obo/GO_1902721 negative regulation of prolactin secretion http://purl.obolibrary.org/obo/GO_0090278 negative regulation of peptide hormone secretion Any process that stops, prevents or reduces the frequency, rate or extent of prolactin secretion. http://purl.obolibrary.org/obo/GO_1903039 positive regulation of leukocyte cell-cell adhesion http://purl.obolibrary.org/obo/GO_0022409 positive regulation of cell-cell adhesion Any process that activates or increases the frequency, rate or extent of leukocyte cell-cell adhesion. http://purl.obolibrary.org/obo/GO_1902722 positive regulation of prolactin secretion http://purl.obolibrary.org/obo/GO_0090277 positive regulation of peptide hormone secretion Any process that activates or increases the frequency, rate or extent of prolactin secretion. http://purl.obolibrary.org/obo/GO_1903169 regulation of calcium ion transmembrane transport http://purl.obolibrary.org/obo/GO_1904062 regulation of monoatomic cation transmembrane transport Any process that modulates the frequency, rate or extent of calcium ion transmembrane transport. http://purl.obolibrary.org/obo/GO_1902723 negative regulation of skeletal muscle satellite cell proliferation http://purl.obolibrary.org/obo/GO_0014859 negative regulation of skeletal muscle cell proliferation Any process that stops, prevents or reduces the frequency, rate or extent of satellite cell proliferation. http://purl.obolibrary.org/obo/GO_1903170 negative regulation of calcium ion transmembrane transport http://purl.obolibrary.org/obo/GO_0051926 negative regulation of calcium ion transport Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion transmembrane transport. http://purl.obolibrary.org/obo/GO_1902724 positive regulation of skeletal muscle satellite cell proliferation http://purl.obolibrary.org/obo/GO_0014858 positive regulation of skeletal muscle cell proliferation Any process that activates or increases the frequency, rate or extent of skeletal muscle satellite cell proliferation. http://purl.obolibrary.org/obo/GO_1903523 negative regulation of blood circulation http://purl.obolibrary.org/obo/GO_0051241 negative regulation of multicellular organismal process Any process that stops, prevents or reduces the frequency, rate or extent of blood circulation. http://purl.obolibrary.org/obo/GO_1902725 negative regulation of satellite cell differentiation http://purl.obolibrary.org/obo/GO_2001015 negative regulation of skeletal muscle cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of satellite cell differentiation. http://purl.obolibrary.org/obo/GO_1903524 positive regulation of blood circulation http://purl.obolibrary.org/obo/GO_0051240 positive regulation of multicellular organismal process Any process that activates or increases the frequency, rate or extent of blood circulation. http://purl.obolibrary.org/obo/GO_1902726 positive regulation of skeletal muscle satellite cell differentiation http://purl.obolibrary.org/obo/GO_2001016 positive regulation of skeletal muscle cell differentiation Any process that activates or increases the frequency, rate or extent of satellite cell differentiation. http://purl.obolibrary.org/obo/GO_1903579 negative regulation of ATP metabolic process http://purl.obolibrary.org/obo/GO_1900543 negative regulation of purine nucleotide metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of ATP metabolic process. http://purl.obolibrary.org/obo/GO_1902729 negative regulation of proteoglycan biosynthetic process http://purl.obolibrary.org/obo/GO_0010561 negative regulation of glycoprotein biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans. http://purl.obolibrary.org/obo/GO_1903580 positive regulation of ATP metabolic process http://purl.obolibrary.org/obo/GO_1900544 positive regulation of purine nucleotide metabolic process Any process that activates or increases the frequency, rate or extent of ATP metabolic process. http://purl.obolibrary.org/obo/GO_1902733 regulation of growth plate cartilage chondrocyte differentiation http://purl.obolibrary.org/obo/GO_1902738 regulation of chondrocyte differentiation involved in endochondral bone morphogenesis Any process that modulates the rate, frequency, or extent of the process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the growth of a bone. A chondrocyte is a polymorphic cell that forms cartilage. http://purl.obolibrary.org/obo/GO_1904180 negative regulation of membrane depolarization http://purl.obolibrary.org/obo/GO_0048519 negative regulation of biological process Any process that stops, prevents or reduces the frequency, rate or extent of membrane depolarization. http://purl.obolibrary.org/obo/GO_1902738 regulation of chondrocyte differentiation involved in endochondral bone morphogenesis http://purl.obolibrary.org/obo/GO_0032330 regulation of chondrocyte differentiation Any process that modulates the rate, frequency, or extent of the process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the development of a bone. A chondrocyte is a polymorphic cell that forms cartilage. http://purl.obolibrary.org/obo/GO_1904181 positive regulation of membrane depolarization http://purl.obolibrary.org/obo/GO_0048518 positive regulation of biological process Any process that activates or increases the frequency, rate or extent of membrane depolarization. http://purl.obolibrary.org/obo/GO_1902746 regulation of lens fiber cell differentiation http://purl.obolibrary.org/obo/GO_0030856 regulation of epithelial cell differentiation Any process that modulates the frequency, rate or extent of lens fiber cell differentiation. http://purl.obolibrary.org/obo/GO_1904397 negative regulation of neuromuscular junction development http://purl.obolibrary.org/obo/GO_1905809 negative regulation of synapse organization Any process that stops, prevents or reduces the frequency, rate or extent of neuromuscular junction development. http://purl.obolibrary.org/obo/GO_1902747 negative regulation of lens fiber cell differentiation http://purl.obolibrary.org/obo/GO_1902746 regulation of lens fiber cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of lens fiber cell differentiation. http://purl.obolibrary.org/obo/GO_1904398 positive regulation of neuromuscular junction development http://purl.obolibrary.org/obo/GO_1904396 regulation of neuromuscular junction development Any process that activates or increases the frequency, rate or extent of neuromuscular junction development. http://purl.obolibrary.org/obo/GO_1904427 positive regulation of calcium ion transmembrane transport http://purl.obolibrary.org/obo/GO_0051928 positive regulation of calcium ion transport Any process that activates or increases the frequency, rate or extent of calcium ion transmembrane transport. http://purl.obolibrary.org/obo/GO_1902748 positive regulation of lens fiber cell differentiation http://purl.obolibrary.org/obo/GO_1902746 regulation of lens fiber cell differentiation Any process that activates or increases the frequency, rate or extent of lens fiber cell differentiation. http://purl.obolibrary.org/obo/GO_1902761 positive regulation of chondrocyte development http://purl.obolibrary.org/obo/GO_0061181 regulation of chondrocyte development Any process that activates or increases the frequency, rate or extent of chondrocyte development. http://purl.obolibrary.org/obo/GO_1904888 cranial skeletal system development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of a cranial skeletal system over time, from its formation to the mature structure. The cranial skeletal system is the skeletal subdivision of the head, and includes the skull (cranium plus mandible), pharyngeal and/or hyoid apparatus. http://purl.obolibrary.org/obo/GO_1902766 skeletal muscle satellite cell migration http://purl.obolibrary.org/obo/GO_0016477 cell migration The orderly movement of a skeletal muscle satellite cell from one site to another. Migration of these cells is a key step in the process of growth and repair of skeletal muscle cells. http://purl.obolibrary.org/obo/GO_1904950 negative regulation of establishment of protein localization http://purl.obolibrary.org/obo/GO_0048519 negative regulation of biological process Any process that stops, prevents or reduces the frequency, rate or extent of establishment of protein localization. http://purl.obolibrary.org/obo/GO_1902809 regulation of skeletal muscle fiber differentiation http://purl.obolibrary.org/obo/GO_0010830 regulation of myotube differentiation Any process that modulates the frequency, rate or extent of skeletal muscle fiber differentiation. http://purl.obolibrary.org/obo/GO_1904951 positive regulation of establishment of protein localization http://purl.obolibrary.org/obo/GO_0048518 positive regulation of biological process Any process that activates or increases the frequency, rate or extent of establishment of protein localization. http://purl.obolibrary.org/obo/GO_1905207 regulation of cardiocyte differentiation http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the frequency, rate or extent of cardiocyte differentiation. http://purl.obolibrary.org/obo/GO_1902810 negative regulation of skeletal muscle fiber differentiation http://purl.obolibrary.org/obo/GO_0010832 negative regulation of myotube differentiation Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle fiber differentiation. http://purl.obolibrary.org/obo/GO_1902811 positive regulation of skeletal muscle fiber differentiation http://purl.obolibrary.org/obo/GO_0010831 positive regulation of myotube differentiation Any process that activates or increases the frequency, rate or extent of skeletal muscle fiber differentiation. http://purl.obolibrary.org/obo/GO_1905208 negative regulation of cardiocyte differentiation http://purl.obolibrary.org/obo/GO_0051241 negative regulation of multicellular organismal process Any process that stops, prevents or reduces the frequency, rate or extent of cardiocyte differentiation. http://purl.obolibrary.org/obo/GO_1905209 positive regulation of cardiocyte differentiation http://purl.obolibrary.org/obo/GO_0045597 positive regulation of cell differentiation Any process that activates or increases the frequency, rate or extent of cardiocyte differentiation. http://purl.obolibrary.org/obo/GO_1902816 regulation of protein localization to microtubule http://purl.obolibrary.org/obo/GO_0032880 regulation of protein localization Any process that modulates the frequency, rate or extent of protein localization to microtubule. http://purl.obolibrary.org/obo/GO_1905517 macrophage migration http://purl.obolibrary.org/obo/GO_0097529 myeloid leukocyte migration The orderly movement of a macrophage from one site to another. http://purl.obolibrary.org/obo/GO_1902817 negative regulation of protein localization to microtubule http://purl.obolibrary.org/obo/GO_1903828 negative regulation of protein localization Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to microtubule. http://purl.obolibrary.org/obo/GO_1905772 positive regulation of mesodermal cell differentiation http://purl.obolibrary.org/obo/GO_0045597 positive regulation of cell differentiation Any process that activates or increases the frequency, rate or extent of mesodermal cell differentiation. http://purl.obolibrary.org/obo/GO_1902832 negative regulation of cell proliferation in dorsal spinal cord http://purl.obolibrary.org/obo/GO_0021921 regulation of cell proliferation in dorsal spinal cord Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation in dorsal spinal cord. http://purl.obolibrary.org/obo/GO_1902833 positive regulation of cell proliferation in dorsal spinal cord http://purl.obolibrary.org/obo/GO_0021921 regulation of cell proliferation in dorsal spinal cord Any process that activates or increases the frequency, rate or extent of cell proliferation in dorsal spinal cord. http://purl.obolibrary.org/obo/GO_1990009 retinal cell apoptotic process http://purl.obolibrary.org/obo/GO_0006915 apoptotic process Any apoptotic process in a retinal cell. http://purl.obolibrary.org/obo/GO_2000171 negative regulation of dendrite development http://purl.obolibrary.org/obo/GO_0010977 negative regulation of neuron projection development Any process that stops, prevents, or reduces the frequency, rate or extent of dendrite development. http://purl.obolibrary.org/obo/GO_1902838 regulation of nuclear migration along microtubule http://purl.obolibrary.org/obo/GO_1902513 regulation of organelle transport along microtubule Any process that modulates the frequency, rate or extent of nuclear migration along microtubule. http://purl.obolibrary.org/obo/GO_2000736 regulation of stem cell differentiation http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the frequency, rate or extent of stem cell differentiation. http://purl.obolibrary.org/obo/GO_1902839 negative regulation of nuclear migration along microtubule http://purl.obolibrary.org/obo/GO_1902838 regulation of nuclear migration along microtubule Any process that stops, prevents or reduces the frequency, rate or extent of nuclear migration along microtubule. http://purl.obolibrary.org/obo/GO_2000737 negative regulation of stem cell differentiation http://purl.obolibrary.org/obo/GO_2000736 regulation of stem cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of stem cell differentiation. http://purl.obolibrary.org/obo/GO_1902840 positive regulation of nuclear migration along microtubule http://purl.obolibrary.org/obo/GO_1902838 regulation of nuclear migration along microtubule Any process that activates or increases the frequency, rate or extent of nuclear migration along microtubule. http://purl.obolibrary.org/obo/GO_1902855 regulation of non-motile cilium assembly http://purl.obolibrary.org/obo/GO_1902017 regulation of cilium assembly Any process that modulates the frequency, rate or extent of non-motile cilium assembly. http://purl.obolibrary.org/obo/GO_2000738 positive regulation of stem cell differentiation http://purl.obolibrary.org/obo/GO_0045597 positive regulation of cell differentiation Any process that activates or increases the frequency, rate or extent of stem cell differentiation. http://purl.obolibrary.org/obo/GO_1902856 negative regulation of non-motile cilium assembly http://purl.obolibrary.org/obo/GO_1902855 regulation of non-motile cilium assembly Any process that stops, prevents or reduces the frequency, rate or extent of non-motile cilium assembly. http://purl.obolibrary.org/obo/GO_2000832 negative regulation of steroid hormone secretion http://purl.obolibrary.org/obo/GO_0046888 negative regulation of hormone secretion Any process that stops, prevents or reduces the frequency, rate or extent of steroid hormone secretion. http://purl.obolibrary.org/obo/GO_1902857 positive regulation of non-motile cilium assembly http://purl.obolibrary.org/obo/GO_1902855 regulation of non-motile cilium assembly Any process that activates or increases the frequency, rate or extent of non-motile cilium assembly. http://purl.obolibrary.org/obo/GO_2000833 positive regulation of steroid hormone secretion http://purl.obolibrary.org/obo/GO_0046887 positive regulation of hormone secretion Any process that activates or increases the frequency, rate or extent of steroid hormone secretion. http://purl.obolibrary.org/obo/GO_1902863 regulation of embryonic camera-type eye development http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of embryonic camera-type eye development. http://purl.obolibrary.org/obo/GO_2000849 regulation of glucocorticoid secretion http://purl.obolibrary.org/obo/GO_2000846 regulation of corticosteroid hormone secretion Any process that modulates the frequency, rate or extent of glucocorticoid secretion. http://purl.obolibrary.org/obo/GO_1902864 negative regulation of embryonic camera-type eye development http://purl.obolibrary.org/obo/GO_1902863 regulation of embryonic camera-type eye development Any process that stops, prevents or reduces the frequency, rate or extent of embryonic camera-type eye development. http://purl.obolibrary.org/obo/GO_1902865 positive regulation of embryonic camera-type eye development http://purl.obolibrary.org/obo/GO_1902863 regulation of embryonic camera-type eye development Any process that activates or increases the frequency, rate or extent of embryonic camera-type eye development. http://purl.obolibrary.org/obo/GO_2000850 negative regulation of glucocorticoid secretion http://purl.obolibrary.org/obo/GO_2000847 negative regulation of corticosteroid hormone secretion Any process that stops, prevents or reduces the frequency, rate or extent of glucocorticoid secretion. http://purl.obolibrary.org/obo/GO_2000851 positive regulation of glucocorticoid secretion http://purl.obolibrary.org/obo/GO_2000848 positive regulation of corticosteroid hormone secretion Any process that activates or increases the frequency, rate or extent of glucocorticoid secretion. http://purl.obolibrary.org/obo/GO_1902869 regulation of amacrine cell differentiation http://purl.obolibrary.org/obo/GO_0045664 regulation of neuron differentiation Any process that modulates the frequency, rate or extent of amacrine cell differentiation. http://purl.obolibrary.org/obo/GO_1902870 negative regulation of amacrine cell differentiation http://purl.obolibrary.org/obo/GO_0045665 negative regulation of neuron differentiation Any process that stops, prevents or reduces the frequency, rate or extent of amacrine cell differentiation. http://purl.obolibrary.org/obo/GO_1903680 acinar cell of sebaceous gland differentiation http://purl.obolibrary.org/obo/GO_0090425 acinar cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of an acinar cell of sebaceous gland. http://purl.obolibrary.org/obo/GO_1903684 regulation of border follicle cell migration http://purl.obolibrary.org/obo/GO_0010632 regulation of epithelial cell migration Any process that modulates the frequency, rate or extent of border follicle cell migration. http://purl.obolibrary.org/obo/GO_1902871 positive regulation of amacrine cell differentiation http://purl.obolibrary.org/obo/GO_0045666 positive regulation of neuron differentiation Any process that activates or increases the frequency, rate or extent of amacrine cell differentiation. http://purl.obolibrary.org/obo/GO_1902908 regulation of melanosome transport http://purl.obolibrary.org/obo/GO_0051049 regulation of transport Any process that modulates the frequency, rate or extent of melanosome transport. http://purl.obolibrary.org/obo/GO_1903687 negative regulation of border follicle cell migration http://purl.obolibrary.org/obo/GO_0010633 negative regulation of epithelial cell migration Any process that stops, prevents or reduces the frequency, rate or extent of border follicle cell migration. http://purl.obolibrary.org/obo/GO_1902909 negative regulation of melanosome transport http://purl.obolibrary.org/obo/GO_0051051 negative regulation of transport Any process that stops, prevents or reduces the frequency, rate or extent of melanosome transport. http://purl.obolibrary.org/obo/GO_1903688 positive regulation of border follicle cell migration http://purl.obolibrary.org/obo/GO_0010634 positive regulation of epithelial cell migration Any process that activates or increases the frequency, rate or extent of border follicle cell migration. http://purl.obolibrary.org/obo/GO_1902910 positive regulation of melanosome transport http://purl.obolibrary.org/obo/GO_0051050 positive regulation of transport Any process that activates or increases the frequency, rate or extent of melanosome transport. http://purl.obolibrary.org/obo/GO_1903697 negative regulation of microvillus assembly http://purl.obolibrary.org/obo/GO_0120033 negative regulation of plasma membrane bounded cell projection assembly Any process that stops, prevents or reduces the frequency, rate or extent of microvillus assembly. http://purl.obolibrary.org/obo/GO_1903000 regulation of lipid transport across blood-brain barrier http://purl.obolibrary.org/obo/GO_0150200 regulation of transport across blood-brain barrier Any process that modulates the frequency, rate or extent of lipid transport across blood-brain barrier. http://purl.obolibrary.org/obo/GO_1903698 positive regulation of microvillus assembly http://purl.obolibrary.org/obo/GO_0120034 positive regulation of plasma membrane bounded cell projection assembly Any process that activates or increases the frequency, rate or extent of microvillus assembly. http://purl.obolibrary.org/obo/GO_1903001 negative regulation of lipid transport across blood-brain barrier http://purl.obolibrary.org/obo/GO_0150202 negative regulation of transport across blood-brain barrier Any process that stops, prevents or reduces the frequency, rate or extent of lipid transport across blood-brain barrier. http://purl.obolibrary.org/obo/GO_1903700 caecum development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of a caecum over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_1903002 positive regulation of lipid transport across blood-brain barrier http://purl.obolibrary.org/obo/GO_0150201 positive regulation of transport across blood-brain barrier Any process that activates or increases the frequency, rate or extent of lipid transport across blood-brain barrier. http://purl.obolibrary.org/obo/GO_1903701 substantia propria of cornea development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of a substantia propria of cornea over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_1903041 regulation of chondrocyte hypertrophy http://purl.obolibrary.org/obo/GO_0061181 regulation of chondrocyte development Any process that modulates the frequency, rate or extent of chondrocyte hypertrophy. http://purl.obolibrary.org/obo/GO_1903702 esophagus development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of an esophagus over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_1903703 enterocyte differentiation http://purl.obolibrary.org/obo/GO_0060575 intestinal epithelial cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of an enterocyte. http://purl.obolibrary.org/obo/GO_1903042 negative regulation of chondrocyte hypertrophy http://purl.obolibrary.org/obo/GO_0061182 negative regulation of chondrocyte development Any process that stops, prevents or reduces the frequency, rate or extent of chondrocyte hypertrophy. http://purl.obolibrary.org/obo/GO_1903043 positive regulation of chondrocyte hypertrophy http://purl.obolibrary.org/obo/GO_1903041 regulation of chondrocyte hypertrophy Any process that activates or increases the frequency, rate or extent of chondrocyte hypertrophy. http://purl.obolibrary.org/obo/GO_1903045 neural crest cell migration involved in sympathetic nervous system development http://purl.obolibrary.org/obo/GO_1901166 neural crest cell migration involved in autonomic nervous system development Any neural crest cell migration that is involved in sympathetic nervous system development. http://purl.obolibrary.org/obo/GO_1903709 uterine gland development http://purl.obolibrary.org/obo/GO_0048732 gland development The process whose specific outcome is the progression of an uterine gland over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_1903056 regulation of melanosome organization http://purl.obolibrary.org/obo/GO_0033043 regulation of organelle organization Any process that modulates the frequency, rate or extent of melanosome organization. http://purl.obolibrary.org/obo/GO_1903057 negative regulation of melanosome organization http://purl.obolibrary.org/obo/GO_0010639 negative regulation of organelle organization Any process that stops, prevents or reduces the frequency, rate or extent of melanosome organization. http://purl.obolibrary.org/obo/GO_1903728 luteal cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a luteal cell. Large luteal cells develop from granulosa cells. Small luteal cells develop from theca cells. http://purl.obolibrary.org/obo/GO_1903058 positive regulation of melanosome organization http://purl.obolibrary.org/obo/GO_0010638 positive regulation of organelle organization Any process that activates or increases the frequency, rate or extent of melanosome organization. http://purl.obolibrary.org/obo/GO_1903764 regulation of potassium ion export across plasma membrane http://purl.obolibrary.org/obo/GO_1901379 regulation of potassium ion transmembrane transport Any process that modulates the frequency, rate or extent of potassium ion export across the plasma membrane. http://purl.obolibrary.org/obo/GO_1903116 positive regulation of actin filament-based movement http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the frequency, rate or extent of actin filament-based movement. http://purl.obolibrary.org/obo/GO_1903765 negative regulation of potassium ion export across plasma membrane http://purl.obolibrary.org/obo/GO_1901380 negative regulation of potassium ion transmembrane transport Any process that stops, prevents or reduces the frequency, rate or extent of potassium ion export across the plasma membrane. http://purl.obolibrary.org/obo/GO_1903120 protein localization to actin filament bundle http://purl.obolibrary.org/obo/GO_1903119 protein localization to actin cytoskeleton A process in which a protein is transported to, or maintained in, the location of an actin filament bundle. http://purl.obolibrary.org/obo/GO_1903766 positive regulation of potassium ion export across plasma membrane http://purl.obolibrary.org/obo/GO_1901381 positive regulation of potassium ion transmembrane transport Any process that activates or increases the frequency, rate or extent of potassium ion export across the plasma membrane. http://purl.obolibrary.org/obo/GO_1903179 regulation of dopamine biosynthetic process http://purl.obolibrary.org/obo/GO_0009889 regulation of biosynthetic process Any process that modulates the frequency, rate or extent of dopamine biosynthetic process. http://purl.obolibrary.org/obo/GO_1903782 regulation of sodium ion import across plasma membrane http://purl.obolibrary.org/obo/GO_1902305 regulation of sodium ion transmembrane transport Any process that modulates the frequency, rate or extent of sodium ion import across the plasma membrane. http://purl.obolibrary.org/obo/GO_1903180 negative regulation of dopamine biosynthetic process http://purl.obolibrary.org/obo/GO_0009890 negative regulation of biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of dopamine biosynthetic process. http://purl.obolibrary.org/obo/GO_1903783 negative regulation of sodium ion import across plasma membrane http://purl.obolibrary.org/obo/GO_1902306 negative regulation of sodium ion transmembrane transport Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion import across the plasma membrane. http://purl.obolibrary.org/obo/GO_1903181 positive regulation of dopamine biosynthetic process http://purl.obolibrary.org/obo/GO_0009891 positive regulation of biosynthetic process Any process that activates or increases the frequency, rate or extent of dopamine biosynthetic process. http://purl.obolibrary.org/obo/GO_1903784 positive regulation of sodium ion import across plasma membrane http://purl.obolibrary.org/obo/GO_1902307 positive regulation of sodium ion transmembrane transport Any process that activates or increases the frequency, rate or extent of sodium ion import across the plasma membrane. http://purl.obolibrary.org/obo/GO_1903210 podocyte apoptotic process http://purl.obolibrary.org/obo/GO_1904019 epithelial cell apoptotic process Any apoptotic process in a glomerular visceral epithelial cell. http://purl.obolibrary.org/obo/GO_1903789 regulation of amino acid transmembrane transport http://purl.obolibrary.org/obo/GO_0034762 regulation of transmembrane transport Any process that modulates the frequency, rate or extent of amino acid transmembrane transport. http://purl.obolibrary.org/obo/GO_1903226 positive regulation of endodermal cell differentiation http://purl.obolibrary.org/obo/GO_0045597 positive regulation of cell differentiation Any process that activates or increases the frequency, rate or extent of endodermal cell differentiation. http://purl.obolibrary.org/obo/GO_1903804 glycine import across plasma membrane http://purl.obolibrary.org/obo/GO_0015816 glycine transport The directed movement of glycine from outside of a cell, across the plasma membrane and into the cytosol. http://purl.obolibrary.org/obo/GO_1903232 melanosome assembly http://purl.obolibrary.org/obo/GO_0032438 melanosome organization The aggregation, arrangement and bonding together of a set of components to form a melanosome, a tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored. http://purl.obolibrary.org/obo/GO_1903847 regulation of aorta morphogenesis http://purl.obolibrary.org/obo/GO_1905651 regulation of artery morphogenesis Any process that modulates the frequency, rate or extent of aorta morphogenesis. http://purl.obolibrary.org/obo/GO_1903233 regulation of calcium ion-dependent exocytosis of neurotransmitter http://purl.obolibrary.org/obo/GO_2000300 regulation of synaptic vesicle exocytosis Any process that modulates the frequency, rate or extent of calcium ion-dependent exocytosis of neurotransmitter. http://purl.obolibrary.org/obo/GO_1903848 negative regulation of aorta morphogenesis http://purl.obolibrary.org/obo/GO_1905652 negative regulation of artery morphogenesis Any process that stops, prevents or reduces the frequency, rate or extent of aorta morphogenesis. http://purl.obolibrary.org/obo/GO_1903234 negative regulation of calcium ion-dependent exocytosis of neurotransmitter http://purl.obolibrary.org/obo/GO_2000301 negative regulation of synaptic vesicle exocytosis Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion-dependent exocytosis of neurotransmitter. http://purl.obolibrary.org/obo/GO_1903235 positive regulation of calcium ion-dependent exocytosis of neurotransmitter http://purl.obolibrary.org/obo/GO_2000302 positive regulation of synaptic vesicle exocytosis Any process that activates or increases the frequency, rate or extent of calcium ion-dependent exocytosis of neurotransmitter. http://purl.obolibrary.org/obo/GO_1903849 positive regulation of aorta morphogenesis http://purl.obolibrary.org/obo/GO_1905653 positive regulation of artery morphogenesis Any process that activates or increases the frequency, rate or extent of aorta morphogenesis. http://purl.obolibrary.org/obo/GO_1903903 regulation of establishment of T cell polarity http://purl.obolibrary.org/obo/GO_2000114 regulation of establishment of cell polarity Any process that modulates the frequency, rate or extent of establishment of T cell polarity. http://purl.obolibrary.org/obo/GO_1903276 regulation of sodium ion export across plasma membrane http://purl.obolibrary.org/obo/GO_1902305 regulation of sodium ion transmembrane transport Any process that modulates the frequency, rate or extent of sodium ion export across the plasma membrane. http://purl.obolibrary.org/obo/GO_1903904 negative regulation of establishment of T cell polarity http://purl.obolibrary.org/obo/GO_0050868 negative regulation of T cell activation Any process that stops, prevents or reduces the frequency, rate or extent of establishment of T cell polarity. http://purl.obolibrary.org/obo/GO_1903277 negative regulation of sodium ion export across plasma membrane http://purl.obolibrary.org/obo/GO_1903276 regulation of sodium ion export across plasma membrane Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion export across the plasma membrane. http://purl.obolibrary.org/obo/GO_1903905 positive regulation of establishment of T cell polarity http://purl.obolibrary.org/obo/GO_0050870 positive regulation of T cell activation Any process that activates or increases the frequency, rate or extent of establishment of T cell polarity. http://purl.obolibrary.org/obo/GO_1903278 positive regulation of sodium ion export across plasma membrane http://purl.obolibrary.org/obo/GO_1903276 regulation of sodium ion export across plasma membrane Any process that activates or increases the frequency, rate or extent of sodium ion export across the plasma membrane. http://purl.obolibrary.org/obo/GO_1903924 estradiol binding http://purl.obolibrary.org/obo/GO_0005496 steroid binding Binding to estradiol. http://purl.obolibrary.org/obo/GO_1903286 regulation of potassium ion import http://purl.obolibrary.org/obo/GO_1901379 regulation of potassium ion transmembrane transport Any process that modulates the frequency, rate or extent of potassium ion import. http://purl.obolibrary.org/obo/GO_1903941 negative regulation of respiratory gaseous exchange http://purl.obolibrary.org/obo/GO_0043576 regulation of respiratory gaseous exchange Any process that stops, prevents or reduces the frequency, rate or extent of respiratory gaseous exchange. http://purl.obolibrary.org/obo/GO_1903287 negative regulation of potassium ion import across plasma membrane http://purl.obolibrary.org/obo/GO_1903286 regulation of potassium ion import Any process that stops, prevents or reduces the frequency, rate or extent of potassium ion import across the plasma membrane. http://purl.obolibrary.org/obo/GO_1903942 positive regulation of respiratory gaseous exchange http://purl.obolibrary.org/obo/GO_0043576 regulation of respiratory gaseous exchange Any process that activates or increases the frequency, rate or extent of respiratory gaseous exchange. http://purl.obolibrary.org/obo/GO_1903288 positive regulation of potassium ion import across plasma membrane http://purl.obolibrary.org/obo/GO_1903286 regulation of potassium ion import Any process that activates or increases the frequency, rate or extent of potassium ion import across the plasma membrane. http://purl.obolibrary.org/obo/GO_1903943 regulation of hepatocyte apoptotic process http://purl.obolibrary.org/obo/GO_1904035 regulation of epithelial cell apoptotic process Any process that modulates the frequency, rate or extent of hepatocyte apoptotic process. http://purl.obolibrary.org/obo/GO_1903292 protein localization to Golgi membrane http://purl.obolibrary.org/obo/GO_0072657 protein localization to membrane A process in which a protein is transported to, or maintained in, a location within a Golgi membrane. http://purl.obolibrary.org/obo/GO_1903944 negative regulation of hepatocyte apoptotic process http://purl.obolibrary.org/obo/GO_1904036 negative regulation of epithelial cell apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of hepatocyte apoptotic process. http://purl.obolibrary.org/obo/GO_1903294 regulation of glutamate secretion, neurotransmission http://purl.obolibrary.org/obo/GO_0051966 regulation of synaptic transmission, glutamatergic Any process that modulates the frequency, rate or extent of glutamate secretion, neurotransmission. http://purl.obolibrary.org/obo/GO_1903945 positive regulation of hepatocyte apoptotic process http://purl.obolibrary.org/obo/GO_1904037 positive regulation of epithelial cell apoptotic process Any process that activates or increases the frequency, rate or extent of hepatocyte apoptotic process. http://purl.obolibrary.org/obo/GO_1903946 negative regulation of ventricular cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_0106135 negative regulation of cardiac muscle cell contraction Any process that stops, prevents or reduces the frequency, rate or extent of ventricular cardiac muscle cell action potential. http://purl.obolibrary.org/obo/GO_1903295 negative regulation of glutamate secretion, neurotransmission http://purl.obolibrary.org/obo/GO_0051967 negative regulation of synaptic transmission, glutamatergic Any process that stops, prevents or reduces the frequency, rate or extent of glutamate secretion, neurotransmission. http://purl.obolibrary.org/obo/GO_1903315 negative regulation of nitrogen cycle metabolic process http://purl.obolibrary.org/obo/GO_0009892 negative regulation of metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of nitrogen cycle metabolic process. http://purl.obolibrary.org/obo/GO_1903947 positive regulation of ventricular cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_0106134 positive regulation of cardiac muscle cell contraction Any process that activates or increases the frequency, rate or extent of ventricular cardiac muscle cell action potential. http://purl.obolibrary.org/obo/GO_1903948 negative regulation of atrial cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_0106135 negative regulation of cardiac muscle cell contraction Any process that stops, prevents or reduces the frequency, rate or extent of atrial cardiac muscle cell action potential. http://purl.obolibrary.org/obo/GO_1903316 positive regulation of nitrogen cycle metabolic process http://purl.obolibrary.org/obo/GO_0009893 positive regulation of metabolic process Any process that activates or increases the frequency, rate or extent of nitrogen cycle metabolic process. http://purl.obolibrary.org/obo/GO_1903326 regulation of tRNA metabolic process http://purl.obolibrary.org/obo/GO_0051252 regulation of RNA metabolic process Any process that modulates the frequency, rate or extent of tRNA metabolic process. http://purl.obolibrary.org/obo/GO_1903949 positive regulation of atrial cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_0098910 regulation of atrial cardiac muscle cell action potential Any process that activates or increases the frequency, rate or extent of atrial cardiac muscle cell action potential. http://purl.obolibrary.org/obo/GO_1903328 positive regulation of tRNA metabolic process http://purl.obolibrary.org/obo/GO_1903326 regulation of tRNA metabolic process Any process that activates or increases the frequency, rate or extent of tRNA metabolic process. http://purl.obolibrary.org/obo/GO_1903950 negative regulation of AV node cell action potential http://purl.obolibrary.org/obo/GO_0098904 regulation of AV node cell action potential Any process that stops, prevents or reduces the frequency, rate or extent of AV node cell action potential. http://purl.obolibrary.org/obo/GO_1903347 negative regulation of bicellular tight junction assembly http://purl.obolibrary.org/obo/GO_2000810 regulation of bicellular tight junction assembly Any process that stops, prevents or reduces the frequency, rate or extent of tight junction assembly. http://purl.obolibrary.org/obo/GO_1903951 positive regulation of AV node cell action potential http://purl.obolibrary.org/obo/GO_0098904 regulation of AV node cell action potential Any process that activates or increases the frequency, rate or extent of AV node cell action potential. http://purl.obolibrary.org/obo/GO_1903348 positive regulation of bicellular tight junction assembly http://purl.obolibrary.org/obo/GO_2000810 regulation of bicellular tight junction assembly Any process that activates or increases the frequency, rate or extent of tight junction assembly. http://purl.obolibrary.org/obo/GO_1903978 regulation of microglial cell activation http://purl.obolibrary.org/obo/GO_0043030 regulation of macrophage activation Any process that modulates the frequency, rate or extent of microglial cell activation. http://purl.obolibrary.org/obo/GO_1903350 response to dopamine http://purl.obolibrary.org/obo/GO_0071869 response to catecholamine Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dopamine stimulus. http://purl.obolibrary.org/obo/GO_1903979 negative regulation of microglial cell activation http://purl.obolibrary.org/obo/GO_0150079 negative regulation of neuroinflammatory response Any process that stops, prevents or reduces the frequency, rate or extent of microglial cell activation. http://purl.obolibrary.org/obo/GO_1903980 positive regulation of microglial cell activation http://purl.obolibrary.org/obo/GO_0150078 positive regulation of neuroinflammatory response Any process that activates or increases the frequency, rate or extent of microglial cell activation. http://purl.obolibrary.org/obo/GO_1903351 cellular response to dopamine http://purl.obolibrary.org/obo/GO_0071870 cellular response to catecholamine stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dopamine stimulus. http://purl.obolibrary.org/obo/GO_1903988 iron ion export across plasma membrane http://purl.obolibrary.org/obo/GO_0140115 export across plasma membrane The directed movement of iron ions from inside of a cell, across the plasma membrane and into the extracellular region. http://purl.obolibrary.org/obo/GO_1903354 regulation of distal tip cell migration http://purl.obolibrary.org/obo/GO_0030334 regulation of cell migration Any process that modulates the frequency, rate or extent of distal tip cell migration. http://purl.obolibrary.org/obo/GO_1903355 negative regulation of distal tip cell migration http://purl.obolibrary.org/obo/GO_1903354 regulation of distal tip cell migration Any process that stops, prevents or reduces the frequency, rate or extent of distal tip cell migration. http://purl.obolibrary.org/obo/GO_1904002 regulation of sebum secreting cell proliferation http://purl.obolibrary.org/obo/GO_0050678 regulation of epithelial cell proliferation Any process that modulates the frequency, rate or extent of sebum secreting cell proliferation. http://purl.obolibrary.org/obo/GO_1904003 negative regulation of sebum secreting cell proliferation http://purl.obolibrary.org/obo/GO_0050680 negative regulation of epithelial cell proliferation Any process that stops, prevents or reduces the frequency, rate or extent of sebum secreting cell proliferation. http://purl.obolibrary.org/obo/GO_1903356 positive regulation of distal tip cell migration http://purl.obolibrary.org/obo/GO_1903354 regulation of distal tip cell migration Any process that activates or increases the frequency, rate or extent of distal tip cell migration. http://purl.obolibrary.org/obo/GO_1903375 facioacoustic ganglion development http://purl.obolibrary.org/obo/GO_0061550 cranial ganglion development The process whose specific outcome is the progression of an acoustico-facial VII-VIII ganglion complex over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_1904004 positive regulation of sebum secreting cell proliferation http://purl.obolibrary.org/obo/GO_0050679 positive regulation of epithelial cell proliferation Any process that activates or increases the frequency, rate or extent of sebum secreting cell proliferation. http://purl.obolibrary.org/obo/GO_1903379 regulation of mitotic chromosome condensation http://purl.obolibrary.org/obo/GO_0060623 regulation of chromosome condensation Any process that modulates the frequency, rate or extent of mitotic chromosome condensation. http://purl.obolibrary.org/obo/GO_1904014 response to serotonin http://purl.obolibrary.org/obo/GO_0071867 response to monoamine Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a serotonin stimulus. http://purl.obolibrary.org/obo/GO_1903380 positive regulation of mitotic chromosome condensation http://purl.obolibrary.org/obo/GO_0090068 positive regulation of cell cycle process Any process that activates or increases the frequency, rate or extent of mitotic chromosome condensation. http://purl.obolibrary.org/obo/GO_1904015 cellular response to serotonin http://purl.obolibrary.org/obo/GO_0071868 cellular response to monoamine stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a serotonin stimulus. http://purl.obolibrary.org/obo/GO_1904026 regulation of collagen fibril organization http://purl.obolibrary.org/obo/GO_1903053 regulation of extracellular matrix organization Any process that modulates the frequency, rate or extent of collagen fibril organization. http://purl.obolibrary.org/obo/GO_1903412 response to bile acid http://purl.obolibrary.org/obo/GO_0033993 response to lipid Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bile acid stimulus. http://purl.obolibrary.org/obo/GO_1904027 negative regulation of collagen fibril organization http://purl.obolibrary.org/obo/GO_1903054 negative regulation of extracellular matrix organization Any process that stops, prevents or reduces the frequency, rate or extent of collagen fibril organization. http://purl.obolibrary.org/obo/GO_1903413 cellular response to bile acid http://purl.obolibrary.org/obo/GO_1903412 response to bile acid Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bile acid stimulus. http://purl.obolibrary.org/obo/GO_1904028 positive regulation of collagen fibril organization http://purl.obolibrary.org/obo/GO_1903055 positive regulation of extracellular matrix organization Any process that activates or increases the frequency, rate or extent of collagen fibril organization. http://purl.obolibrary.org/obo/GO_1903439 calcitonin family receptor complex http://purl.obolibrary.org/obo/GO_0097648 G protein-coupled receptor complex A protein complex which is capable of calcitonin family receptor activity. Calcitonin family receptors may form dimers, trimers or tetramers; adrenomedullin and amylin receptors have only been observed as dimers so far. http://purl.obolibrary.org/obo/GO_1904038 regulation of iron export across plasma membrane http://purl.obolibrary.org/obo/GO_0034759 regulation of iron ion transmembrane transport Any process that modulates the frequency, rate or extent of export of iron ions from inside of a cell, across the plasma membrane and into the extracellular region. http://purl.obolibrary.org/obo/GO_1903444 negative regulation of brown fat cell differentiation http://purl.obolibrary.org/obo/GO_0090335 regulation of brown fat cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of brown fat cell differentiation. http://purl.obolibrary.org/obo/GO_1904039 negative regulation of iron export across plasma membrane http://purl.obolibrary.org/obo/GO_0034760 negative regulation of iron ion transmembrane transport Any process that stops, prevents or reduces the frequency, rate or extent of export of iron ions from inside of a cell, across the plasma membrane and into the extracellular region. http://purl.obolibrary.org/obo/GO_1903487 regulation of lactation http://purl.obolibrary.org/obo/GO_2000026 regulation of multicellular organismal development Any process that modulates the frequency, rate or extent of lactation. http://purl.obolibrary.org/obo/GO_1904040 positive regulation of iron export across plasma membrane http://purl.obolibrary.org/obo/GO_0034761 positive regulation of iron ion transmembrane transport Any process that activates or increases the frequency, rate or extent of export of iron ions from inside of a cell, across the plasma membrane and into the extracellular region. http://purl.obolibrary.org/obo/GO_1903488 negative regulation of lactation http://purl.obolibrary.org/obo/GO_1903487 regulation of lactation Any process that stops, prevents or reduces the frequency, rate or extent of lactation. http://purl.obolibrary.org/obo/GO_1904044 response to aldosterone http://purl.obolibrary.org/obo/GO_0097305 response to alcohol Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aldosterone stimulus. http://purl.obolibrary.org/obo/GO_1903537 meiotic cell cycle process involved in oocyte maturation http://purl.obolibrary.org/obo/GO_1903046 meiotic cell cycle process Any meiotic cell cycle process that is involved in oocyte maturation. http://purl.obolibrary.org/obo/GO_1904045 cellular response to aldosterone http://purl.obolibrary.org/obo/GO_0110096 cellular response to aldehyde Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aldosterone stimulus. http://purl.obolibrary.org/obo/GO_1903538 regulation of meiotic cell cycle process involved in oocyte maturation http://purl.obolibrary.org/obo/GO_2000241 regulation of reproductive process Any process that modulates the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation. http://purl.obolibrary.org/obo/GO_1904054 regulation of cholangiocyte proliferation http://purl.obolibrary.org/obo/GO_0050678 regulation of epithelial cell proliferation Any process that modulates the frequency, rate or extent of cholangiocyte proliferation. http://purl.obolibrary.org/obo/GO_1903541 regulation of exosomal secretion http://purl.obolibrary.org/obo/GO_0017157 regulation of exocytosis Any process that modulates the frequency, rate or extent of exosomal secretion. http://purl.obolibrary.org/obo/GO_1904055 negative regulation of cholangiocyte proliferation http://purl.obolibrary.org/obo/GO_0050680 negative regulation of epithelial cell proliferation Any process that stops, prevents or reduces the frequency, rate or extent of cholangiocyte proliferation. http://purl.obolibrary.org/obo/GO_1903542 negative regulation of exosomal secretion http://purl.obolibrary.org/obo/GO_1903541 regulation of exosomal secretion Any process that stops, prevents or reduces the frequency, rate or extent of exosomal secretion. http://purl.obolibrary.org/obo/GO_1903543 positive regulation of exosomal secretion http://purl.obolibrary.org/obo/GO_0044089 positive regulation of cellular component biogenesis Any process that activates or increases the frequency, rate or extent of exosomal secretion. http://purl.obolibrary.org/obo/GO_1904056 positive regulation of cholangiocyte proliferation http://purl.obolibrary.org/obo/GO_0050679 positive regulation of epithelial cell proliferation Any process that activates or increases the frequency, rate or extent of cholangiocyte proliferation. http://purl.obolibrary.org/obo/GO_1903551 regulation of extracellular exosome assembly http://purl.obolibrary.org/obo/GO_1902115 regulation of organelle assembly Any process that modulates the frequency, rate or extent of extracellular vesicular exosome assembly. http://purl.obolibrary.org/obo/GO_1904057 negative regulation of sensory perception of pain http://purl.obolibrary.org/obo/GO_0051930 regulation of sensory perception of pain Any process that stops, prevents or reduces the frequency, rate or extent of sensory perception of pain. http://purl.obolibrary.org/obo/GO_1904058 positive regulation of sensory perception of pain http://purl.obolibrary.org/obo/GO_0051930 regulation of sensory perception of pain Any process that activates or increases the frequency, rate or extent of sensory perception of pain. http://purl.obolibrary.org/obo/GO_1903552 negative regulation of extracellular exosome assembly http://purl.obolibrary.org/obo/GO_1902116 negative regulation of organelle assembly Any process that stops, prevents or reduces the frequency, rate or extent of extracellular vesicular exosome assembly. http://purl.obolibrary.org/obo/GO_1903553 positive regulation of extracellular exosome assembly http://purl.obolibrary.org/obo/GO_1902117 positive regulation of organelle assembly Any process that activates or increases the frequency, rate or extent of extracellular vesicular exosome assembly. http://purl.obolibrary.org/obo/GO_1904073 regulation of trophectodermal cell proliferation http://purl.obolibrary.org/obo/GO_0048638 regulation of developmental growth Any process that modulates the frequency, rate or extent of trophectodermal cell proliferation. http://purl.obolibrary.org/obo/GO_1904074 negative regulation of trophectodermal cell proliferation http://purl.obolibrary.org/obo/GO_0008285 negative regulation of cell population proliferation Any process that stops, prevents or reduces the frequency, rate or extent of trophectodermal cell proliferation. http://purl.obolibrary.org/obo/GO_1903564 regulation of protein localization to cilium http://purl.obolibrary.org/obo/GO_0032880 regulation of protein localization Any process that modulates the frequency, rate or extent of protein localization to cilium. http://purl.obolibrary.org/obo/GO_1904075 positive regulation of trophectodermal cell proliferation http://purl.obolibrary.org/obo/GO_0008284 positive regulation of cell population proliferation Any process that activates or increases the frequency, rate or extent of trophectodermal cell proliferation. http://purl.obolibrary.org/obo/GO_1903565 negative regulation of protein localization to cilium http://purl.obolibrary.org/obo/GO_1903828 negative regulation of protein localization Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cilium. http://purl.obolibrary.org/obo/GO_1903566 positive regulation of protein localization to cilium http://purl.obolibrary.org/obo/GO_1903564 regulation of protein localization to cilium Any process that activates or increases the frequency, rate or extent of protein localization to cilium. http://purl.obolibrary.org/obo/GO_1904098 regulation of protein O-linked glycosylation http://purl.obolibrary.org/obo/GO_0010559 regulation of glycoprotein biosynthetic process Any process that modulates the frequency, rate or extent of protein O-linked glycosylation. http://purl.obolibrary.org/obo/GO_1904099 negative regulation of protein O-linked glycosylation http://purl.obolibrary.org/obo/GO_0010561 negative regulation of glycoprotein biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of protein O-linked glycosylation. http://purl.obolibrary.org/obo/GO_1903567 regulation of protein localization to ciliary membrane http://purl.obolibrary.org/obo/GO_1904375 regulation of protein localization to cell periphery Any process that modulates the frequency, rate or extent of protein localization to ciliary membrane. http://purl.obolibrary.org/obo/GO_1904100 positive regulation of protein O-linked glycosylation http://purl.obolibrary.org/obo/GO_0010560 positive regulation of glycoprotein biosynthetic process Any process that activates or increases the frequency, rate or extent of protein O-linked glycosylation. http://purl.obolibrary.org/obo/GO_1903568 negative regulation of protein localization to ciliary membrane http://purl.obolibrary.org/obo/GO_1904376 negative regulation of protein localization to cell periphery Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to ciliary membrane. http://purl.obolibrary.org/obo/GO_1904106 protein localization to microvillus http://purl.obolibrary.org/obo/GO_0008104 intracellular protein localization A process in which a protein is transported to, or maintained in, a location within a microvillus. http://purl.obolibrary.org/obo/GO_1903569 positive regulation of protein localization to ciliary membrane http://purl.obolibrary.org/obo/GO_1904377 positive regulation of protein localization to cell periphery Any process that activates or increases the frequency, rate or extent of protein localization to ciliary membrane. http://purl.obolibrary.org/obo/GO_1903581 regulation of basophil degranulation http://purl.obolibrary.org/obo/GO_0043300 regulation of leukocyte degranulation Any process that modulates the frequency, rate or extent of basophil degranulation. http://purl.obolibrary.org/obo/GO_1904116 response to vasopressin http://purl.obolibrary.org/obo/GO_0043434 response to peptide hormone Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vasopressin stimulus. http://purl.obolibrary.org/obo/GO_1903582 negative regulation of basophil degranulation http://purl.obolibrary.org/obo/GO_1903581 regulation of basophil degranulation Any process that stops, prevents or reduces the frequency, rate or extent of basophil degranulation. http://purl.obolibrary.org/obo/GO_1904117 cellular response to vasopressin http://purl.obolibrary.org/obo/GO_0071375 cellular response to peptide hormone stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vasopressin stimulus. http://purl.obolibrary.org/obo/GO_1903583 positive regulation of basophil degranulation http://purl.obolibrary.org/obo/GO_1903581 regulation of basophil degranulation Any process that activates or increases the frequency, rate or extent of basophil degranulation. http://purl.obolibrary.org/obo/GO_1904118 regulation of otic vesicle morphogenesis http://purl.obolibrary.org/obo/GO_2000027 regulation of animal organ morphogenesis Any process that modulates the frequency, rate or extent of otic vesicle morphogenesis. http://purl.obolibrary.org/obo/GO_1903593 regulation of histamine secretion by mast cell http://purl.obolibrary.org/obo/GO_0051239 regulation of multicellular organismal process Any process that modulates the frequency, rate or extent of histamine secretion by mast cell. http://purl.obolibrary.org/obo/GO_1904119 negative regulation of otic vesicle morphogenesis http://purl.obolibrary.org/obo/GO_1905331 negative regulation of morphogenesis of an epithelium Any process that stops, prevents or reduces the frequency, rate or extent of otic vesicle morphogenesis. http://purl.obolibrary.org/obo/GO_1903594 negative regulation of histamine secretion by mast cell http://purl.obolibrary.org/obo/GO_1903593 regulation of histamine secretion by mast cell Any process that stops, prevents or reduces the frequency, rate or extent of histamine secretion by mast cell. http://purl.obolibrary.org/obo/GO_1904120 positive regulation of otic vesicle morphogenesis http://purl.obolibrary.org/obo/GO_1905332 positive regulation of morphogenesis of an epithelium Any process that activates or increases the frequency, rate or extent of otic vesicle morphogenesis. http://purl.obolibrary.org/obo/GO_1903595 positive regulation of histamine secretion by mast cell http://purl.obolibrary.org/obo/GO_1903593 regulation of histamine secretion by mast cell Any process that activates or increases the frequency, rate or extent of histamine secretion by mast cell. http://purl.obolibrary.org/obo/GO_1904124 microglial cell migration http://purl.obolibrary.org/obo/GO_0008347 glial cell migration The orderly movement of a microglial cell from one site to another. http://purl.obolibrary.org/obo/GO_1904139 regulation of microglial cell migration http://purl.obolibrary.org/obo/GO_1905521 regulation of macrophage migration Any process that modulates the frequency, rate or extent of microglial cell migration. http://purl.obolibrary.org/obo/GO_1903624 regulation of DNA catabolic process http://purl.obolibrary.org/obo/GO_0009894 regulation of catabolic process Any process that modulates the frequency, rate or extent of DNA catabolic process. http://purl.obolibrary.org/obo/GO_1904140 negative regulation of microglial cell migration http://purl.obolibrary.org/obo/GO_1905522 negative regulation of macrophage migration Any process that stops, prevents or reduces the frequency, rate or extent of microglial cell migration. http://purl.obolibrary.org/obo/GO_1903625 negative regulation of DNA catabolic process http://purl.obolibrary.org/obo/GO_0009895 negative regulation of catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of DNA catabolic process. http://purl.obolibrary.org/obo/GO_1904141 positive regulation of microglial cell migration http://purl.obolibrary.org/obo/GO_1905523 positive regulation of macrophage migration Any process that activates or increases the frequency, rate or extent of microglial cell migration. http://purl.obolibrary.org/obo/GO_1903626 positive regulation of DNA catabolic process http://purl.obolibrary.org/obo/GO_0009896 positive regulation of catabolic process Any process that activates or increases the frequency, rate or extent of DNA catabolic process. http://purl.obolibrary.org/obo/GO_1903748 negative regulation of protein localization to mitochondrion http://purl.obolibrary.org/obo/GO_1903828 negative regulation of protein localization Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to mitochondrion. http://purl.obolibrary.org/obo/GO_1904142 negative regulation of carotenoid biosynthetic process http://purl.obolibrary.org/obo/GO_0051055 negative regulation of lipid biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of carotenoid biosynthetic process. http://purl.obolibrary.org/obo/GO_1904143 positive regulation of carotenoid biosynthetic process http://purl.obolibrary.org/obo/GO_0046889 positive regulation of lipid biosynthetic process Any process that activates or increases the frequency, rate or extent of carotenoid biosynthetic process. http://purl.obolibrary.org/obo/GO_1903780 negative regulation of cardiac conduction http://purl.obolibrary.org/obo/GO_1903779 regulation of cardiac conduction Any process that stops, prevents or reduces the frequency, rate or extent of cardiac conduction. http://purl.obolibrary.org/obo/GO_1903781 positive regulation of cardiac conduction http://purl.obolibrary.org/obo/GO_1903779 regulation of cardiac conduction Any process that activates or increases the frequency, rate or extent of cardiac conduction. http://purl.obolibrary.org/obo/GO_1904145 negative regulation of meiotic cell cycle process involved in oocyte maturation http://purl.obolibrary.org/obo/GO_0010948 negative regulation of cell cycle process Any process that stops, prevents or reduces the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation. http://purl.obolibrary.org/obo/GO_1903817 negative regulation of voltage-gated potassium channel activity http://purl.obolibrary.org/obo/GO_1901017 negative regulation of potassium ion transmembrane transporter activity Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated potassium channel activity. http://purl.obolibrary.org/obo/GO_1904146 positive regulation of meiotic cell cycle process involved in oocyte maturation http://purl.obolibrary.org/obo/GO_0090068 positive regulation of cell cycle process Any process that activates or increases the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation. http://purl.obolibrary.org/obo/GO_1903818 positive regulation of voltage-gated potassium channel activity http://purl.obolibrary.org/obo/GO_2001259 positive regulation of cation channel activity Any process that activates or increases the frequency, rate or extent of voltage-gated potassium channel activity. http://purl.obolibrary.org/obo/GO_1904149 regulation of microglial cell mediated cytotoxicity http://purl.obolibrary.org/obo/GO_0002886 regulation of myeloid leukocyte mediated immunity Any process that modulates the frequency, rate or extent of microglial cell mediated cytotoxicity. http://purl.obolibrary.org/obo/GO_1904035 regulation of epithelial cell apoptotic process http://purl.obolibrary.org/obo/GO_0042981 regulation of apoptotic process Any process that modulates the frequency, rate or extent of epithelial cell apoptotic process. http://purl.obolibrary.org/obo/GO_1904150 negative regulation of microglial cell mediated cytotoxicity http://purl.obolibrary.org/obo/GO_0002887 negative regulation of myeloid leukocyte mediated immunity Any process that stops, prevents or reduces the frequency, rate or extent of microglial cell mediated cytotoxicity. http://purl.obolibrary.org/obo/GO_1904036 negative regulation of epithelial cell apoptotic process http://purl.obolibrary.org/obo/GO_1904035 regulation of epithelial cell apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell apoptotic process. http://purl.obolibrary.org/obo/GO_1904151 positive regulation of microglial cell mediated cytotoxicity http://purl.obolibrary.org/obo/GO_0002888 positive regulation of myeloid leukocyte mediated immunity Any process that activates or increases the frequency, rate or extent of microglial cell mediated cytotoxicity. http://purl.obolibrary.org/obo/GO_1904037 positive regulation of epithelial cell apoptotic process http://purl.obolibrary.org/obo/GO_0043065 positive regulation of apoptotic process Any process that activates or increases the frequency, rate or extent of epithelial cell apoptotic process. http://purl.obolibrary.org/obo/GO_1904155 DN2 thymocyte differentiation http://purl.obolibrary.org/obo/GO_0033077 T cell differentiation in thymus The process in which a relatively unspecialized cell acquires the specialized features of a DN2 thymocyte. A DN2 thymocyte is a CD4-,CD8- thymocyte that is also CD44+,CD25-. http://purl.obolibrary.org/obo/GO_1904375 regulation of protein localization to cell periphery http://purl.obolibrary.org/obo/GO_0032880 regulation of protein localization Any process that modulates the frequency, rate or extent of protein localization to cell periphery. http://purl.obolibrary.org/obo/GO_1904376 negative regulation of protein localization to cell periphery http://purl.obolibrary.org/obo/GO_1903828 negative regulation of protein localization Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell periphery. http://purl.obolibrary.org/obo/GO_1904156 DN3 thymocyte differentiation http://purl.obolibrary.org/obo/GO_0033077 T cell differentiation in thymus The process in which a relatively unspecialized cell acquires the specialized features of a DN3 thymocyte. A DN3 thymocyte is a CD4-,CD8- thymocyte that is also CD44+,CD25+. http://purl.obolibrary.org/obo/GO_1904377 positive regulation of protein localization to cell periphery http://purl.obolibrary.org/obo/GO_1904375 regulation of protein localization to cell periphery Any process that activates or increases the frequency, rate or extent of protein localization to cell periphery. http://purl.obolibrary.org/obo/GO_1904157 DN4 thymocyte differentiation http://purl.obolibrary.org/obo/GO_0033077 T cell differentiation in thymus The process in which a relatively unspecialized cell acquires the specialized features of a DN4 thymocyte. A DN4 thymocyte is a CD4-,CD8- thymocyte that is also CD44-,CD25-. http://purl.obolibrary.org/obo/GO_1904491 protein localization to ciliary transition zone http://purl.obolibrary.org/obo/GO_0061512 protein localization to cilium A process in which a protein is transported to, or maintained in, a location within a ciliary transition zone. http://purl.obolibrary.org/obo/GO_1904158 axonemal central apparatus assembly http://purl.obolibrary.org/obo/GO_0022607 cellular component assembly The aggregation, arrangement and bonding together of a set of components to form an axonemal central apparatus. http://purl.obolibrary.org/obo/GO_1904170 regulation of bleb assembly http://purl.obolibrary.org/obo/GO_0120032 regulation of plasma membrane bounded cell projection assembly Any process that modulates the frequency, rate or extent of bleb assembly. http://purl.obolibrary.org/obo/GO_1904809 regulation of dense core granule transport http://purl.obolibrary.org/obo/GO_0032386 regulation of intracellular transport Any process that modulates the frequency, rate or extent of dense core granule transport. http://purl.obolibrary.org/obo/GO_1904171 negative regulation of bleb assembly http://purl.obolibrary.org/obo/GO_0120033 negative regulation of plasma membrane bounded cell projection assembly Any process that stops, prevents or reduces the frequency, rate or extent of bleb assembly. http://purl.obolibrary.org/obo/GO_1904810 negative regulation of dense core granule transport http://purl.obolibrary.org/obo/GO_1904809 regulation of dense core granule transport Any process that stops, prevents or reduces the frequency, rate or extent of dense core granule transport. http://purl.obolibrary.org/obo/GO_1904811 positive regulation of dense core granule transport http://purl.obolibrary.org/obo/GO_1904809 regulation of dense core granule transport Any process that activates or increases the frequency, rate or extent of dense core granule transport. http://purl.obolibrary.org/obo/GO_1904172 positive regulation of bleb assembly http://purl.obolibrary.org/obo/GO_0120034 positive regulation of plasma membrane bounded cell projection assembly Any process that activates or increases the frequency, rate or extent of bleb assembly. http://purl.obolibrary.org/obo/GO_1905216 positive regulation of RNA binding http://purl.obolibrary.org/obo/GO_0051099 positive regulation of binding Any process that activates or increases the frequency, rate or extent of RNA binding. http://purl.obolibrary.org/obo/GO_1904177 regulation of adipose tissue development http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of adipose tissue development. http://purl.obolibrary.org/obo/GO_1905483 regulation of motor neuron migration http://purl.obolibrary.org/obo/GO_2001222 regulation of neuron migration Any process that modulates the frequency, rate or extent of motor neuron migration. http://purl.obolibrary.org/obo/GO_1904178 negative regulation of adipose tissue development http://purl.obolibrary.org/obo/GO_0051241 negative regulation of multicellular organismal process Any process that stops, prevents or reduces the frequency, rate or extent of adipose tissue development. http://purl.obolibrary.org/obo/GO_1905484 negative regulation of motor neuron migration http://purl.obolibrary.org/obo/GO_1905483 regulation of motor neuron migration Any process that stops, prevents or reduces the frequency, rate or extent of motor neuron migration. http://purl.obolibrary.org/obo/GO_1905485 positive regulation of motor neuron migration http://purl.obolibrary.org/obo/GO_1905483 regulation of motor neuron migration Any process that activates or increases the frequency, rate or extent of motor neuron migration. http://purl.obolibrary.org/obo/GO_1904179 positive regulation of adipose tissue development http://purl.obolibrary.org/obo/GO_0051240 positive regulation of multicellular organismal process Any process that activates or increases the frequency, rate or extent of adipose tissue development. http://purl.obolibrary.org/obo/GO_1904192 regulation of cholangiocyte apoptotic process http://purl.obolibrary.org/obo/GO_1904035 regulation of epithelial cell apoptotic process Any process that modulates the frequency, rate or extent of cholangiocyte apoptotic process. http://purl.obolibrary.org/obo/GO_1905755 protein localization to cytoplasmic microtubule http://purl.obolibrary.org/obo/GO_0035372 protein localization to microtubule A process in which a protein is transported to, or maintained in, a location within a cytoplasmic microtubule. http://purl.obolibrary.org/obo/GO_1904193 negative regulation of cholangiocyte apoptotic process http://purl.obolibrary.org/obo/GO_1904036 negative regulation of epithelial cell apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of cholangiocyte apoptotic process. http://purl.obolibrary.org/obo/GO_1904194 positive regulation of cholangiocyte apoptotic process http://purl.obolibrary.org/obo/GO_1904037 positive regulation of epithelial cell apoptotic process Any process that activates or increases the frequency, rate or extent of cholangiocyte apoptotic process. http://purl.obolibrary.org/obo/GO_1905821 positive regulation of chromosome condensation http://purl.obolibrary.org/obo/GO_0060623 regulation of chromosome condensation Any process that activates or increases the frequency, rate or extent of chromosome condensation. http://purl.obolibrary.org/obo/GO_1990010 compound eye retinal cell apoptotic process http://purl.obolibrary.org/obo/GO_1990009 retinal cell apoptotic process Any apoptotic process in a compound eye retinal cell. http://purl.obolibrary.org/obo/GO_1904195 regulation of granulosa cell proliferation http://purl.obolibrary.org/obo/GO_0050678 regulation of epithelial cell proliferation Any process that modulates the frequency, rate or extent of granulosa cell proliferation. http://purl.obolibrary.org/obo/GO_1904196 negative regulation of granulosa cell proliferation http://purl.obolibrary.org/obo/GO_0050680 negative regulation of epithelial cell proliferation Any process that stops, prevents or reduces the frequency, rate or extent of granulosa cell proliferation. http://purl.obolibrary.org/obo/GO_1990048 anterograde neuronal dense core vesicle transport http://purl.obolibrary.org/obo/GO_0099519 dense core granule cytoskeletal transport The directed movement of substances in neuronal dense core vesicles along axonal microtubules towards the presynapse. http://purl.obolibrary.org/obo/GO_1904197 positive regulation of granulosa cell proliferation http://purl.obolibrary.org/obo/GO_0050679 positive regulation of epithelial cell proliferation Any process that activates or increases the frequency, rate or extent of granulosa cell proliferation. http://purl.obolibrary.org/obo/GO_1990049 retrograde neuronal dense core vesicle transport http://purl.obolibrary.org/obo/GO_0099519 dense core granule cytoskeletal transport The directed movement of neuronal dense core vesicles along axonal microtubules towards the cell body. http://purl.obolibrary.org/obo/GO_1990079 cartilage homeostasis http://purl.obolibrary.org/obo/GO_0001894 tissue homeostasis A tissue homeostatic process involved in the maintenance of an internal equilibrium within cartilage, including control of cellular proliferation and death and control of metabolic function. http://purl.obolibrary.org/obo/GO_1904204 regulation of skeletal muscle hypertrophy http://purl.obolibrary.org/obo/GO_0014743 regulation of muscle hypertrophy Any process that modulates the frequency, rate or extent of skeletal muscle hypertrophy. http://purl.obolibrary.org/obo/GO_1990239 steroid hormone binding http://purl.obolibrary.org/obo/GO_0042562 hormone binding Binding to a steroid hormone. http://purl.obolibrary.org/obo/GO_1990379 lipid transport across blood-brain barrier http://purl.obolibrary.org/obo/GO_0006869 lipid transport The directed movement of lipid molecules passing through the blood-brain barrier. http://purl.obolibrary.org/obo/GO_1904205 negative regulation of skeletal muscle hypertrophy http://purl.obolibrary.org/obo/GO_0014745 negative regulation of muscle adaptation Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle hypertrophy. http://purl.obolibrary.org/obo/GO_2000036 regulation of stem cell population maintenance http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of stem cell population maintenance. http://purl.obolibrary.org/obo/GO_1904206 positive regulation of skeletal muscle hypertrophy http://purl.obolibrary.org/obo/GO_0014744 positive regulation of muscle adaptation Any process that activates or increases the frequency, rate or extent of skeletal muscle hypertrophy. http://purl.obolibrary.org/obo/GO_1904215 regulation of protein import into chloroplast stroma http://purl.obolibrary.org/obo/GO_0051223 regulation of protein transport Any process that modulates the frequency, rate or extent of protein import into chloroplast stroma. http://purl.obolibrary.org/obo/GO_2000211 regulation of glutamate metabolic process http://purl.obolibrary.org/obo/GO_0006521 regulation of amino acid metabolic process Any process that modulates the frequency, rate or extent of glutamate metabolic process. http://purl.obolibrary.org/obo/GO_1904216 positive regulation of protein import into chloroplast stroma http://purl.obolibrary.org/obo/GO_0051222 positive regulation of protein transport Any process that activates or increases the frequency, rate or extent of protein import into chloroplast stroma. http://purl.obolibrary.org/obo/GO_2000212 negative regulation of glutamate metabolic process http://purl.obolibrary.org/obo/GO_2000211 regulation of glutamate metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of glutamate metabolic process. http://purl.obolibrary.org/obo/GO_1904266 regulation of Schwann cell chemotaxis http://purl.obolibrary.org/obo/GO_1900147 regulation of Schwann cell migration Any process that modulates the frequency, rate or extent of Schwann cell chemotaxis. http://purl.obolibrary.org/obo/GO_2000331 regulation of terminal button organization http://purl.obolibrary.org/obo/GO_0099174 regulation of presynapse organization Any process that modulates the frequency, rate or extent of terminal button organization. http://purl.obolibrary.org/obo/GO_1904267 negative regulation of Schwann cell chemotaxis http://purl.obolibrary.org/obo/GO_1900148 negative regulation of Schwann cell migration Any process that stops, prevents or reduces the frequency, rate or extent of Schwann cell chemotaxis. http://purl.obolibrary.org/obo/GO_2000401 regulation of lymphocyte migration http://purl.obolibrary.org/obo/GO_0071675 regulation of mononuclear cell migration Any process that modulates the frequency, rate or extent of lymphocyte migration. http://purl.obolibrary.org/obo/GO_1904268 positive regulation of Schwann cell chemotaxis http://purl.obolibrary.org/obo/GO_1900149 positive regulation of Schwann cell migration Any process that activates or increases the frequency, rate or extent of Schwann cell chemotaxis. http://purl.obolibrary.org/obo/GO_2000402 negative regulation of lymphocyte migration http://purl.obolibrary.org/obo/GO_0071676 negative regulation of mononuclear cell migration Any process that stops, prevents or reduces the frequency, rate or extent of lymphocyte migration. http://purl.obolibrary.org/obo/GO_1904304 regulation of gastro-intestinal system smooth muscle contraction http://purl.obolibrary.org/obo/GO_0006940 regulation of smooth muscle contraction Any process that modulates the frequency, rate or extent of gastro-intestinal system smooth muscle contraction. http://purl.obolibrary.org/obo/GO_2000810 regulation of bicellular tight junction assembly http://purl.obolibrary.org/obo/GO_1901888 regulation of cell junction assembly Any process that modulates the frequency, rate or extent of tight junction assembly. http://purl.obolibrary.org/obo/GO_1904305 negative regulation of gastro-intestinal system smooth muscle contraction http://purl.obolibrary.org/obo/GO_1904304 regulation of gastro-intestinal system smooth muscle contraction Any process that stops, prevents or reduces the frequency, rate or extent of gastro-intestinal system smooth muscle contraction. http://purl.obolibrary.org/obo/GO_2001014 regulation of skeletal muscle cell differentiation http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the frequency, rate or extent of skeletal muscle cell differentiation. http://purl.obolibrary.org/obo/GO_1904306 positive regulation of gastro-intestinal system smooth muscle contraction http://purl.obolibrary.org/obo/GO_1904304 regulation of gastro-intestinal system smooth muscle contraction Any process that activates or increases the frequency, rate or extent of gastro-intestinal system smooth muscle contraction. http://purl.obolibrary.org/obo/GO_2001015 negative regulation of skeletal muscle cell differentiation http://purl.obolibrary.org/obo/GO_2001014 regulation of skeletal muscle cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle cell differentiation. http://purl.obolibrary.org/obo/GO_1904338 regulation of dopaminergic neuron differentiation http://purl.obolibrary.org/obo/GO_0045664 regulation of neuron differentiation Any process that modulates the frequency, rate or extent of dopaminergic neuron differentiation. http://purl.obolibrary.org/obo/GO_2001016 positive regulation of skeletal muscle cell differentiation http://purl.obolibrary.org/obo/GO_0045597 positive regulation of cell differentiation Any process that activates or increases the frequency, rate or extent of skeletal muscle cell differentiation. http://purl.obolibrary.org/obo/GO_1904339 negative regulation of dopaminergic neuron differentiation http://purl.obolibrary.org/obo/GO_0045665 negative regulation of neuron differentiation Any process that stops, prevents or reduces the frequency, rate or extent of dopaminergic neuron differentiation. http://purl.obolibrary.org/obo/GO_2001017 regulation of retrograde axon cargo transport http://purl.obolibrary.org/obo/GO_0032386 regulation of intracellular transport Any process that modulates the frequency, rate or extent of retrograde axon cargo transport. http://purl.obolibrary.org/obo/GO_1904340 positive regulation of dopaminergic neuron differentiation http://purl.obolibrary.org/obo/GO_0045666 positive regulation of neuron differentiation Any process that activates or increases the frequency, rate or extent of dopaminergic neuron differentiation. http://purl.obolibrary.org/obo/GO_2001018 negative regulation of retrograde axon cargo transport http://purl.obolibrary.org/obo/GO_2001017 regulation of retrograde axon cargo transport Any process that stops, prevents or reduces the frequency, rate or extent of retrograde axon cargo transport. http://purl.obolibrary.org/obo/GO_1904341 regulation of colon smooth muscle contraction http://purl.obolibrary.org/obo/GO_1904304 regulation of gastro-intestinal system smooth muscle contraction Any process that modulates the frequency, rate or extent of colon smooth muscle contraction. http://purl.obolibrary.org/obo/GO_2001019 positive regulation of retrograde axon cargo transport http://purl.obolibrary.org/obo/GO_2001017 regulation of retrograde axon cargo transport Any process that activates or increases the frequency, rate or extent of retrograde axon cargo transport. http://purl.obolibrary.org/obo/GO_1904342 negative regulation of colon smooth muscle contraction http://purl.obolibrary.org/obo/GO_1904341 regulation of colon smooth muscle contraction Any process that stops, prevents or reduces the frequency, rate or extent of colon smooth muscle contraction. http://purl.obolibrary.org/obo/GO_2001236 regulation of extrinsic apoptotic signaling pathway http://purl.obolibrary.org/obo/GO_2001233 regulation of apoptotic signaling pathway Any process that modulates the frequency, rate or extent of extrinsic apoptotic signaling pathway. http://purl.obolibrary.org/obo/GO_1904343 positive regulation of colon smooth muscle contraction http://purl.obolibrary.org/obo/GO_1904341 regulation of colon smooth muscle contraction Any process that activates or increases the frequency, rate or extent of colon smooth muscle contraction. http://purl.obolibrary.org/obo/GO_2001237 negative regulation of extrinsic apoptotic signaling pathway http://purl.obolibrary.org/obo/GO_2001236 regulation of extrinsic apoptotic signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of extrinsic apoptotic signaling pathway. http://purl.obolibrary.org/obo/GO_1904344 regulation of gastric mucosal blood circulation http://purl.obolibrary.org/obo/GO_1903522 regulation of blood circulation Any process that modulates the frequency, rate or extent of gastric mucosal blood circulation. http://purl.obolibrary.org/obo/GO_2001238 positive regulation of extrinsic apoptotic signaling pathway http://purl.obolibrary.org/obo/GO_2001236 regulation of extrinsic apoptotic signaling pathway Any process that activates or increases the frequency, rate or extent of extrinsic apoptotic signaling pathway. http://purl.obolibrary.org/obo/GO_1904345 negative regulation of gastric mucosal blood circulation http://purl.obolibrary.org/obo/GO_1904344 regulation of gastric mucosal blood circulation Any process that stops, prevents or reduces the frequency, rate or extent of gastric mucosal blood circulation. http://purl.obolibrary.org/obo/GO_1905632 protein localization to euchromatin http://purl.obolibrary.org/obo/GO_0071168 protein localization to chromatin A process in which a protein is transported to, or maintained in, a location within an euchromatin. http://purl.obolibrary.org/obo/GO_1904346 positive regulation of gastric mucosal blood circulation http://purl.obolibrary.org/obo/GO_1904344 regulation of gastric mucosal blood circulation Any process that activates or increases the frequency, rate or extent of gastric mucosal blood circulation. http://purl.obolibrary.org/obo/GO_1905633 establishment of protein localization to euchromatin http://purl.obolibrary.org/obo/GO_0071169 establishment of protein localization to chromatin The directed movement of a protein to a specific location in an euchromatin. http://purl.obolibrary.org/obo/GO_1904347 regulation of small intestine smooth muscle contraction http://purl.obolibrary.org/obo/GO_1904304 regulation of gastro-intestinal system smooth muscle contraction Any process that modulates the frequency, rate or extent of small intestine smooth muscle contraction. http://purl.obolibrary.org/obo/GO_1905664 regulation of calcium ion import across plasma membrane http://purl.obolibrary.org/obo/GO_1903169 regulation of calcium ion transmembrane transport Any process that modulates the frequency, rate or extent of calcium ion import across plasma membrane. http://purl.obolibrary.org/obo/GO_1904348 negative regulation of small intestine smooth muscle contraction http://purl.obolibrary.org/obo/GO_1904347 regulation of small intestine smooth muscle contraction Any process that stops, prevents or reduces the frequency, rate or extent of small intestine smooth muscle contraction. http://purl.obolibrary.org/obo/GO_1905665 positive regulation of calcium ion import across plasma membrane http://purl.obolibrary.org/obo/GO_1905664 regulation of calcium ion import across plasma membrane Any process that activates or increases the frequency, rate or extent of calcium ion import across plasma membrane. http://purl.obolibrary.org/obo/GO_1904349 positive regulation of small intestine smooth muscle contraction http://purl.obolibrary.org/obo/GO_1904347 regulation of small intestine smooth muscle contraction Any process that activates or increases the frequency, rate or extent of small intestine smooth muscle contraction. http://purl.obolibrary.org/obo/GO_1905671 regulation of lysosome organization http://purl.obolibrary.org/obo/GO_0044088 regulation of vacuole organization Any process that modulates the frequency, rate or extent of lysosome organization. http://purl.obolibrary.org/obo/GO_1904350 regulation of protein catabolic process in the vacuole http://purl.obolibrary.org/obo/GO_0042176 regulation of protein catabolic process Any process that modulates the frequency, rate or extent of protein catabolic process in the vacuole. http://purl.obolibrary.org/obo/GO_1905672 negative regulation of lysosome organization http://purl.obolibrary.org/obo/GO_0010639 negative regulation of organelle organization Any process that stops, prevents or reduces the frequency, rate or extent of lysosome organization. http://purl.obolibrary.org/obo/GO_1904351 negative regulation of protein catabolic process in the vacuole http://purl.obolibrary.org/obo/GO_0042177 negative regulation of protein catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of protein catabolic process in the vacuole. http://purl.obolibrary.org/obo/GO_1905673 positive regulation of lysosome organization http://purl.obolibrary.org/obo/GO_1905671 regulation of lysosome organization Any process that activates or increases the frequency, rate or extent of lysosome organization. http://purl.obolibrary.org/obo/GO_1905720 cytoplasmic microtubule bundle http://purl.obolibrary.org/obo/GO_0097427 microtubule bundle Any microtubule bundle that is part of a cytoplasm. http://purl.obolibrary.org/obo/GO_1904352 positive regulation of protein catabolic process in the vacuole http://purl.obolibrary.org/obo/GO_0045732 positive regulation of protein catabolic process Any process that activates or increases the frequency, rate or extent of protein catabolic process in the vacuole. http://purl.obolibrary.org/obo/GO_1905747 negative regulation of saliva secretion http://purl.obolibrary.org/obo/GO_0060457 negative regulation of digestive system process Any process that stops, prevents or reduces the frequency, rate or extent of saliva secretion. http://purl.obolibrary.org/obo/GO_1905788 negative regulation of detection of mechanical stimulus involved in sensory perception of touch http://purl.obolibrary.org/obo/GO_0032102 negative regulation of response to external stimulus Any process that stops, prevents or reduces the frequency, rate or extent of detection of mechanical stimulus involved in sensory perception of touch. http://purl.obolibrary.org/obo/GO_1904362 regulation of calcitonin secretion http://purl.obolibrary.org/obo/GO_0090276 regulation of peptide hormone secretion Any process that modulates the frequency, rate or extent of calcitonin secretion. http://purl.obolibrary.org/obo/GO_1905789 positive regulation of detection of mechanical stimulus involved in sensory perception of touch http://purl.obolibrary.org/obo/GO_0031646 positive regulation of nervous system process Any process that activates or increases the frequency, rate or extent of detection of mechanical stimulus involved in sensory perception of touch. http://purl.obolibrary.org/obo/GO_1904363 negative regulation of calcitonin secretion http://purl.obolibrary.org/obo/GO_1904362 regulation of calcitonin secretion Any process that stops, prevents or reduces the frequency, rate or extent of calcitonin secretion. http://purl.obolibrary.org/obo/GO_1905805 excitatory synapse pruning http://purl.obolibrary.org/obo/GO_0098883 synapse pruning The disaggregation of an excitatory synapse into its constituent components. http://purl.obolibrary.org/obo/GO_1904364 positive regulation of calcitonin secretion http://purl.obolibrary.org/obo/GO_0090277 positive regulation of peptide hormone secretion Any process that activates or increases the frequency, rate or extent of calcitonin secretion. http://purl.obolibrary.org/obo/GO_1905806 regulation of synapse pruning http://purl.obolibrary.org/obo/GO_0050807 regulation of synapse organization Any process that modulates the frequency, rate or extent of synapse pruning. http://purl.obolibrary.org/obo/GO_1904389 rod bipolar cell differentiation http://purl.obolibrary.org/obo/GO_0060040 retinal bipolar neuron differentiation The process in which a relatively unspecialized cell acquires the specialized features of a rod bipolar cell. http://purl.obolibrary.org/obo/GO_1905807 negative regulation of synapse pruning http://purl.obolibrary.org/obo/GO_1905809 negative regulation of synapse organization Any process that stops, prevents or reduces the frequency, rate or extent of synapse pruning. http://purl.obolibrary.org/obo/GO_1905808 positive regulation of synapse pruning http://purl.obolibrary.org/obo/GO_0051130 positive regulation of cellular component organization Any process that activates or increases the frequency, rate or extent of synapse pruning. http://purl.obolibrary.org/obo/GO_1905810 regulation of excitatory synapse pruning http://purl.obolibrary.org/obo/GO_1905806 regulation of synapse pruning Any process that modulates the frequency, rate or extent of excitatory synapse pruning. http://purl.obolibrary.org/obo/GO_1904390 cone retinal bipolar cell differentiation http://purl.obolibrary.org/obo/GO_0060040 retinal bipolar neuron differentiation The process in which a relatively unspecialized cell acquires the specialized features of a cone retinal bipolar cell. http://purl.obolibrary.org/obo/GO_1905811 negative regulation of excitatory synapse pruning http://purl.obolibrary.org/obo/GO_1905810 regulation of excitatory synapse pruning Any process that stops, prevents or reduces the frequency, rate or extent of excitatory synapse pruning. http://purl.obolibrary.org/obo/GO_1905833 negative regulation of microtubule nucleation http://purl.obolibrary.org/obo/GO_0010968 regulation of microtubule nucleation Any process that stops, prevents or reduces the frequency, rate or extent of microtubule nucleation. http://purl.obolibrary.org/obo/GO_1904408 melatonin binding http://purl.obolibrary.org/obo/GO_0005488 binding Binding to melatonin. http://purl.obolibrary.org/obo/GO_1905867 epididymis development http://purl.obolibrary.org/obo/GO_0035295 tube development The process whose specific outcome is the progression of an epididymis over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_1904409 regulation of secretory granule organization http://purl.obolibrary.org/obo/GO_0033043 regulation of organelle organization Any process that modulates the frequency, rate or extent of secretory granule organization. http://purl.obolibrary.org/obo/GO_1905871 regulation of protein localization to cell leading edge http://purl.obolibrary.org/obo/GO_0032880 regulation of protein localization Any process that modulates the frequency, rate or extent of protein localization to cell leading edge. http://purl.obolibrary.org/obo/GO_1905872 negative regulation of protein localization to cell leading edge http://purl.obolibrary.org/obo/GO_1903828 negative regulation of protein localization Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell leading edge. http://purl.obolibrary.org/obo/GO_1905873 positive regulation of protein localization to cell leading edge http://purl.obolibrary.org/obo/GO_1905871 regulation of protein localization to cell leading edge Any process that activates or increases the frequency, rate or extent of protein localization to cell leading edge. http://purl.obolibrary.org/obo/GO_1904410 negative regulation of secretory granule organization http://purl.obolibrary.org/obo/GO_0010639 negative regulation of organelle organization Any process that stops, prevents or reduces the frequency, rate or extent of secretory granule organization. http://purl.obolibrary.org/obo/GO_1905899 regulation of smooth muscle tissue development http://purl.obolibrary.org/obo/GO_1901861 regulation of muscle tissue development Any process that modulates the frequency, rate or extent of smooth muscle tissue development. http://purl.obolibrary.org/obo/GO_1904411 positive regulation of secretory granule organization http://purl.obolibrary.org/obo/GO_0010638 positive regulation of organelle organization Any process that activates or increases the frequency, rate or extent of secretory granule organization. http://purl.obolibrary.org/obo/GO_1904412 regulation of cardiac ventricle development http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of cardiac ventricle development. http://purl.obolibrary.org/obo/GO_1905900 negative regulation of smooth muscle tissue development http://purl.obolibrary.org/obo/GO_1905899 regulation of smooth muscle tissue development Any process that stops, prevents or reduces the frequency, rate or extent of smooth muscle tissue development. http://purl.obolibrary.org/obo/GO_1904413 negative regulation of cardiac ventricle development http://purl.obolibrary.org/obo/GO_0051241 negative regulation of multicellular organismal process Any process that stops, prevents or reduces the frequency, rate or extent of cardiac ventricle development. http://purl.obolibrary.org/obo/GO_1905901 positive regulation of smooth muscle tissue development http://purl.obolibrary.org/obo/GO_1905899 regulation of smooth muscle tissue development Any process that activates or increases the frequency, rate or extent of smooth muscle tissue development. http://purl.obolibrary.org/obo/GO_1904414 positive regulation of cardiac ventricle development http://purl.obolibrary.org/obo/GO_0051240 positive regulation of multicellular organismal process Any process that activates or increases the frequency, rate or extent of cardiac ventricle development. http://purl.obolibrary.org/obo/GO_1905902 regulation of mesoderm formation http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of mesoderm formation. http://purl.obolibrary.org/obo/GO_1904438 regulation of iron ion import across plasma membrane http://purl.obolibrary.org/obo/GO_0060341 regulation of cellular localization Any process that modulates the frequency, rate or extent of iron ions import across plasma membrane. http://purl.obolibrary.org/obo/GO_1905903 negative regulation of mesoderm formation http://purl.obolibrary.org/obo/GO_1905902 regulation of mesoderm formation Any process that stops, prevents or reduces the frequency, rate or extent of mesoderm formation. http://purl.obolibrary.org/obo/GO_1904439 negative regulation of iron ion import across plasma membrane http://purl.obolibrary.org/obo/GO_0034760 negative regulation of iron ion transmembrane transport Any process that stops, prevents or reduces the frequency, rate or extent of iron ions import across plasma membrane. http://purl.obolibrary.org/obo/GO_1905904 positive regulation of mesoderm formation http://purl.obolibrary.org/obo/GO_1905902 regulation of mesoderm formation Any process that activates or increases the frequency, rate or extent of mesoderm formation. http://purl.obolibrary.org/obo/GO_1904440 positive regulation of iron ion import across plasma membrane http://purl.obolibrary.org/obo/GO_0034761 positive regulation of iron ion transmembrane transport Any process that activates or increases the frequency, rate or extent of iron ions import across plasma membrane. http://purl.obolibrary.org/obo/GO_1905912 regulation of calcium ion export across plasma membrane http://purl.obolibrary.org/obo/GO_1903169 regulation of calcium ion transmembrane transport Any process that modulates the frequency, rate or extent of calcium ion export across the plasma membrane. http://purl.obolibrary.org/obo/GO_1904456 negative regulation of neuronal action potential http://purl.obolibrary.org/obo/GO_0051970 negative regulation of transmission of nerve impulse Any process that stops, prevents or reduces the frequency, rate or extent of neuronal action potential. http://purl.obolibrary.org/obo/GO_1905913 negative regulation of calcium ion export across plasma membrane http://purl.obolibrary.org/obo/GO_1905912 regulation of calcium ion export across plasma membrane Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion export across the plasma membrane. http://purl.obolibrary.org/obo/GO_1904457 positive regulation of neuronal action potential http://purl.obolibrary.org/obo/GO_0051971 positive regulation of transmission of nerve impulse Any process that activates or increases the frequency, rate or extent of neuronal action potential. http://purl.obolibrary.org/obo/GO_1905914 positive regulation of calcium ion export across plasma membrane http://purl.obolibrary.org/obo/GO_1905912 regulation of calcium ion export across plasma membrane Any process that activates or increases the frequency, rate or extent of calcium ion export across the plasma membrane. http://purl.obolibrary.org/obo/GO_1904484 cloacal gland development http://purl.obolibrary.org/obo/GO_0048732 gland development The process whose specific outcome is the progression of a cloacal gland over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_1905921 regulation of acetylcholine biosynthetic process http://purl.obolibrary.org/obo/GO_0060408 regulation of acetylcholine metabolic process Any process that modulates the frequency, rate or extent of acetylcholine biosynthetic process. http://purl.obolibrary.org/obo/GO_1904516 myofibroblast cell apoptotic process http://purl.obolibrary.org/obo/GO_0006915 apoptotic process Any apoptotic process in a myofibroblast cell. http://purl.obolibrary.org/obo/GO_1905922 negative regulation of acetylcholine biosynthetic process http://purl.obolibrary.org/obo/GO_0009890 negative regulation of biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of acetylcholine biosynthetic process. http://purl.obolibrary.org/obo/GO_1904520 regulation of myofibroblast cell apoptotic process http://purl.obolibrary.org/obo/GO_0042981 regulation of apoptotic process Any process that modulates the frequency, rate or extent of myofibroblast cell apoptotic process. http://purl.obolibrary.org/obo/GO_1905923 positive regulation of acetylcholine biosynthetic process http://purl.obolibrary.org/obo/GO_0060409 positive regulation of acetylcholine metabolic process Any process that activates or increases the frequency, rate or extent of acetylcholine biosynthetic process. http://purl.obolibrary.org/obo/GO_1904521 negative regulation of myofibroblast cell apoptotic process http://purl.obolibrary.org/obo/GO_1904520 regulation of myofibroblast cell apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of myofibroblast cell apoptotic process. http://purl.obolibrary.org/obo/GO_1905936 regulation of germ cell proliferation http://purl.obolibrary.org/obo/GO_0051239 regulation of multicellular organismal process Any process that modulates the frequency, rate or extent of germ cell proliferation. http://purl.obolibrary.org/obo/GO_1904522 positive regulation of myofibroblast cell apoptotic process http://purl.obolibrary.org/obo/GO_0043065 positive regulation of apoptotic process Any process that activates or increases the frequency, rate or extent of myofibroblast cell apoptotic process. http://purl.obolibrary.org/obo/GO_1905937 negative regulation of germ cell proliferation http://purl.obolibrary.org/obo/GO_0008285 negative regulation of cell population proliferation Any process that stops, prevents or reduces the frequency, rate or extent of germ cell proliferation. http://purl.obolibrary.org/obo/GO_1904588 cellular response to glycoprotein http://purl.obolibrary.org/obo/GO_1904587 response to glycoprotein Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycoprotein stimulus. http://purl.obolibrary.org/obo/GO_1905938 positive regulation of germ cell proliferation http://purl.obolibrary.org/obo/GO_1905936 regulation of germ cell proliferation Any process that activates or increases the frequency, rate or extent of germ cell proliferation. http://purl.obolibrary.org/obo/GO_1904602 serotonin-activated cation-selective channel complex http://purl.obolibrary.org/obo/GO_0098878 neurotransmitter receptor complex A protein complex which is capable of serotonin-activated cation-selective channel activity. Mainly found in pre- and postsynaptic membranes of the brain and gastrointestinal tract. Depending on its location it transports Ca2+, Mg2+, Na+ or K+. It is always a pentamer, containing at least the 5HT3A subunit forming 5HT3A homopentamers or 5HT3A/B heteropentamers. In human, 5HT3A/C, A/D and A/E heteropentamers also exist. http://purl.obolibrary.org/obo/GO_1905939 regulation of gonad development http://purl.obolibrary.org/obo/GO_2000241 regulation of reproductive process Any process that modulates the frequency, rate or extent of gonad development. http://purl.obolibrary.org/obo/GO_1905940 negative regulation of gonad development http://purl.obolibrary.org/obo/GO_2000242 negative regulation of reproductive process Any process that stops, prevents or reduces the frequency, rate or extent of gonad development. http://purl.obolibrary.org/obo/GO_1904606 fat cell apoptotic process http://purl.obolibrary.org/obo/GO_0006915 apoptotic process Any apoptotic process in a fat cell. http://purl.obolibrary.org/obo/GO_1905941 positive regulation of gonad development http://purl.obolibrary.org/obo/GO_2000243 positive regulation of reproductive process Any process that activates or increases the frequency, rate or extent of gonad development. http://purl.obolibrary.org/obo/GO_1904624 regulation of glycine secretion, neurotransmission http://purl.obolibrary.org/obo/GO_0060092 regulation of synaptic transmission, glycinergic Any process that modulates the frequency, rate or extent of glycine secretion, neurotransmission. http://purl.obolibrary.org/obo/GO_1905945 regulation of response to calcium ion http://purl.obolibrary.org/obo/GO_0048583 regulation of response to stimulus Any process that modulates the frequency, rate or extent of response to calcium ion. http://purl.obolibrary.org/obo/GO_1904625 negative regulation of glycine secretion, neurotransmission http://purl.obolibrary.org/obo/GO_0060093 negative regulation of synaptic transmission, glycinergic Any process that stops, prevents or reduces the frequency, rate or extent of glycine secretion, neurotransmission. http://purl.obolibrary.org/obo/GO_1905946 negative regulation of response to calcium ion http://purl.obolibrary.org/obo/GO_1905945 regulation of response to calcium ion Any process that stops, prevents or reduces the frequency, rate or extent of response to calcium ion. http://purl.obolibrary.org/obo/GO_1904626 positive regulation of glycine secretion, neurotransmission http://purl.obolibrary.org/obo/GO_0060094 positive regulation of synaptic transmission, glycinergic Any process that activates or increases the frequency, rate or extent of glycine secretion, neurotransmission. http://purl.obolibrary.org/obo/GO_1905947 positive regulation of response to calcium ion http://purl.obolibrary.org/obo/GO_1905945 regulation of response to calcium ion Any process that activates or increases the frequency, rate or extent of response to calcium ion. http://purl.obolibrary.org/obo/GO_1904633 regulation of podocyte apoptotic process http://purl.obolibrary.org/obo/GO_1904035 regulation of epithelial cell apoptotic process Any process that modulates the frequency, rate or extent of glomerular visceral epithelial cell apoptotic process. http://purl.obolibrary.org/obo/GO_1905949 negative regulation of calcium ion import across plasma membrane http://purl.obolibrary.org/obo/GO_1905664 regulation of calcium ion import across plasma membrane Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion import across plasma membrane. http://purl.obolibrary.org/obo/GO_1904634 negative regulation of podocyte apoptotic process http://purl.obolibrary.org/obo/GO_1904036 negative regulation of epithelial cell apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of glomerular visceral epithelial cell apoptotic process. http://purl.obolibrary.org/obo/GO_1990034 calcium ion export across plasma membrane http://purl.obolibrary.org/obo/GO_0140115 export across plasma membrane The directed movement of calcium ions from inside of a cell, across the plasma membrane and into the extracellular region. http://purl.obolibrary.org/obo/GO_1904635 positive regulation of podocyte apoptotic process http://purl.obolibrary.org/obo/GO_1904037 positive regulation of epithelial cell apoptotic process Any process that activates or increases the frequency, rate or extent of glomerular visceral epithelial cell apoptotic process. http://purl.obolibrary.org/obo/GO_1990086 lens fiber cell apoptotic process http://purl.obolibrary.org/obo/GO_1904019 epithelial cell apoptotic process Any apoptotic process in a lens fiber cell. Lens fiber cells are elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye. http://purl.obolibrary.org/obo/GO_1904649 regulation of fat cell apoptotic process http://purl.obolibrary.org/obo/GO_0042981 regulation of apoptotic process Any process that modulates the frequency, rate or extent of fat cell apoptotic process. http://purl.obolibrary.org/obo/GO_1990254 keratin filament binding http://purl.obolibrary.org/obo/GO_0019215 intermediate filament binding Binding to a keratin filament, an intermediate filament composed of acidic and basic keratins (types I and II), typically expressed in epithelial cells. http://purl.obolibrary.org/obo/GO_1904650 negative regulation of fat cell apoptotic process http://purl.obolibrary.org/obo/GO_1904649 regulation of fat cell apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of fat cell apoptotic process. http://purl.obolibrary.org/obo/GO_1990280 RNA localization to chromatin http://purl.obolibrary.org/obo/GO_0006403 RNA localization A process in which RNA is transported to and maintained in a part of a chromosome that is organized into chromatin. http://purl.obolibrary.org/obo/GO_1904651 positive regulation of fat cell apoptotic process http://purl.obolibrary.org/obo/GO_0043065 positive regulation of apoptotic process Any process that activates or increases the frequency, rate or extent of fat cell apoptotic process. http://purl.obolibrary.org/obo/GO_1990375 baculum development http://purl.obolibrary.org/obo/GO_0048608 reproductive structure development The reproductive developmental process whose specific outcome is the progression of the baculum over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_1904653 regulation of lung alveolus development http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of lung alveolus development. http://purl.obolibrary.org/obo/GO_1990461 detoxification of iron ion http://purl.obolibrary.org/obo/GO_0061687 detoxification of inorganic compound Any process that reduces or removes the toxicity of iron ion. These include transport of iron away from sensitive areas and to compartments or complexes whose purpose is sequestration of iron ion. http://purl.obolibrary.org/obo/GO_1904654 negative regulation of lung alveolus development http://purl.obolibrary.org/obo/GO_0051241 negative regulation of multicellular organismal process Any process that stops, prevents or reduces the frequency, rate or extent of lung alveolus development. http://purl.obolibrary.org/obo/GO_1990497 regulation of cytoplasmic translation in response to stress http://purl.obolibrary.org/obo/GO_2000765 regulation of cytoplasmic translation Modulation of the frequency, rate or extent of cytoplasmic translation as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). http://purl.obolibrary.org/obo/GO_1904655 positive regulation of lung alveolus development http://purl.obolibrary.org/obo/GO_0051240 positive regulation of multicellular organismal process Any process that activates or increases the frequency, rate or extent of lung alveolus development. http://purl.obolibrary.org/obo/GO_1904675 regulation of somatic stem cell division http://purl.obolibrary.org/obo/GO_2000035 regulation of stem cell division Any process that modulates the frequency, rate or extent of somatic stem cell division. http://purl.obolibrary.org/obo/GO_1990502 dense core granule maturation http://purl.obolibrary.org/obo/GO_0061792 secretory granule maturation Steps required to transform a dense core granule generated at the trans-Golgi network into a fully formed and transmissible dense core granule. Dense core granule maturation proceeds through clathrin-mediated membrane remodeling events and is essential for efficient processing of cargo within dense core granules as well as for removing factors that might otherwise interfere with dense core granule trafficking and exocytosis. http://purl.obolibrary.org/obo/GO_1904676 negative regulation of somatic stem cell division http://purl.obolibrary.org/obo/GO_0051782 negative regulation of cell division Any process that stops, prevents or reduces the frequency, rate or extent of somatic stem cell division. http://purl.obolibrary.org/obo/GO_1990544 mitochondrial ATP transmembrane transport http://purl.obolibrary.org/obo/GO_1901679 nucleotide transmembrane transport The process in which ATP is transported across a mitochondrial membrane, into or out of the mitochondrion. http://purl.obolibrary.org/obo/GO_1904677 positive regulation of somatic stem cell division http://purl.obolibrary.org/obo/GO_0051781 positive regulation of cell division Any process that activates or increases the frequency, rate or extent of somatic stem cell division. http://purl.obolibrary.org/obo/GO_1904691 negative regulation of type B pancreatic cell proliferation http://purl.obolibrary.org/obo/GO_0061469 regulation of type B pancreatic cell proliferation Any process that stops, prevents or reduces the frequency, rate or extent of type B pancreatic cell proliferation. http://purl.obolibrary.org/obo/GO_1990547 mitochondrial phosphate ion transmembrane transport http://purl.obolibrary.org/obo/GO_0035435 phosphate ion transmembrane transport The process in which a phosphate ion is transported across a mitochondrial membrane, into or out of the mitochondrion. http://purl.obolibrary.org/obo/GO_1904692 positive regulation of type B pancreatic cell proliferation http://purl.obolibrary.org/obo/GO_0061469 regulation of type B pancreatic cell proliferation Any process that activates or increases the frequency, rate or extent of type B pancreatic cell proliferation. http://purl.obolibrary.org/obo/GO_1990573 potassium ion import across plasma membrane http://purl.obolibrary.org/obo/GO_0098659 inorganic cation import across plasma membrane The directed movement of potassium ions from outside of a cell, across the plasma membrane and into the cytosol. http://purl.obolibrary.org/obo/GO_1904693 midbrain morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The developmental process by which a midbrain is generated and organized. http://purl.obolibrary.org/obo/GO_1990580 regulation of cytoplasmic translational termination http://purl.obolibrary.org/obo/GO_2000765 regulation of cytoplasmic translation Any process that modulates the frequency, rate or extent of cytoplasmic translational termination. http://purl.obolibrary.org/obo/GO_1904697 regulation of acinar cell proliferation http://purl.obolibrary.org/obo/GO_0050678 regulation of epithelial cell proliferation Any process that modulates the frequency, rate or extent of acinar cell proliferation. http://purl.obolibrary.org/obo/GO_1990611 regulation of cytoplasmic translational initiation in response to stress http://purl.obolibrary.org/obo/GO_0043558 regulation of translational initiation in response to stress Modulation of the frequency, rate or extent of cytoplasmic translational initiation as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). http://purl.obolibrary.org/obo/GO_1904698 negative regulation of acinar cell proliferation http://purl.obolibrary.org/obo/GO_0050680 negative regulation of epithelial cell proliferation Any process that stops, prevents or reduces the frequency, rate or extent of acinar cell proliferation. http://purl.obolibrary.org/obo/GO_1990625 negative regulation of cytoplasmic translational initiation in response to stress http://purl.obolibrary.org/obo/GO_1990611 regulation of cytoplasmic translational initiation in response to stress Any process that stops, prevents or reduces the rate of cytoplasmic translation initiation as a result of a stimulus indicating the organism is under stress. http://purl.obolibrary.org/obo/GO_1904699 positive regulation of acinar cell proliferation http://purl.obolibrary.org/obo/GO_0050679 positive regulation of epithelial cell proliferation Any process that activates or increases the frequency, rate or extent of acinar cell proliferation. http://purl.obolibrary.org/obo/GO_1990806 ligand-gated ion channel signaling pathway http://purl.obolibrary.org/obo/GO_0007165 signal transduction The series of molecular signals initiated by activation of a ligand-gated ion channel on the surface of a cell. The pathway begins with binding of an extracellular ligand to a ligand-gated ion channel and ends with a molecular function that directly regulates a downstream cellular process, e.g. transcription. http://purl.obolibrary.org/obo/GO_1904700 granulosa cell apoptotic process http://purl.obolibrary.org/obo/GO_1904019 epithelial cell apoptotic process Any apoptotic process in a granulosa cell. http://purl.obolibrary.org/obo/GO_1904705 regulation of vascular associated smooth muscle cell proliferation http://purl.obolibrary.org/obo/GO_0048660 regulation of smooth muscle cell proliferation Any process that modulates the frequency, rate or extent of vascular smooth muscle cell proliferation. http://purl.obolibrary.org/obo/GO_1990849 vacuolar localization http://purl.obolibrary.org/obo/GO_0051640 organelle localization Any process in which the vacuole is transported to, and/or maintained in, a specific location within the cell. http://purl.obolibrary.org/obo/GO_1990917 ooplasm http://purl.obolibrary.org/obo/GO_0005737 cytoplasm The cytoplasm of an ovum. http://purl.obolibrary.org/obo/GO_1904706 negative regulation of vascular associated smooth muscle cell proliferation http://purl.obolibrary.org/obo/GO_1904705 regulation of vascular associated smooth muscle cell proliferation Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle cell proliferation. http://purl.obolibrary.org/obo/GO_1990959 eosinophil homeostasis http://purl.obolibrary.org/obo/GO_0002262 myeloid cell homeostasis The process of regulating the proliferation and elimination of eosinophils such that the total number of eosinophils within a whole or part of an organism is stable over time in the absence of an outside stimulus. http://purl.obolibrary.org/obo/GO_1904707 positive regulation of vascular associated smooth muscle cell proliferation http://purl.obolibrary.org/obo/GO_1904705 regulation of vascular associated smooth muscle cell proliferation Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell proliferation. http://purl.obolibrary.org/obo/GO_1990960 basophil homeostasis http://purl.obolibrary.org/obo/GO_0002262 myeloid cell homeostasis The process of regulating the proliferation and elimination of basophils such that the total number of basophils within a whole or part of an organism is stable over time in the absence of an outside stimulus. http://purl.obolibrary.org/obo/GO_1904708 regulation of granulosa cell apoptotic process http://purl.obolibrary.org/obo/GO_1904035 regulation of epithelial cell apoptotic process Any process that modulates the frequency, rate or extent of granulosa cell apoptotic process. http://purl.obolibrary.org/obo/GO_1904709 negative regulation of granulosa cell apoptotic process http://purl.obolibrary.org/obo/GO_1904036 negative regulation of epithelial cell apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of granulosa cell apoptotic process. http://purl.obolibrary.org/obo/GO_2000004 regulation of metanephric S-shaped body morphogenesis http://purl.obolibrary.org/obo/GO_2000027 regulation of animal organ morphogenesis Any process that modulates the frequency, rate or extent of metanephric S-shaped body morphogenesis. http://purl.obolibrary.org/obo/GO_1904710 positive regulation of granulosa cell apoptotic process http://purl.obolibrary.org/obo/GO_1904037 positive regulation of epithelial cell apoptotic process Any process that activates or increases the frequency, rate or extent of granulosa cell apoptotic process. http://purl.obolibrary.org/obo/GO_2000005 negative regulation of metanephric S-shaped body morphogenesis http://purl.obolibrary.org/obo/GO_2000004 regulation of metanephric S-shaped body morphogenesis Any process that stops, prevents, or reduces the frequency, rate or extent of metanephric S-shaped body morphogenesis. http://purl.obolibrary.org/obo/GO_1904724 tertiary granule lumen http://purl.obolibrary.org/obo/GO_0070013 intracellular organelle lumen Any membrane-enclosed lumen that is part of a tertiary granule. http://purl.obolibrary.org/obo/GO_2000006 regulation of metanephric comma-shaped body morphogenesis http://purl.obolibrary.org/obo/GO_2000027 regulation of animal organ morphogenesis Any process that modulates the frequency, rate or extent of metanephric comma-shaped body morphogenesis. http://purl.obolibrary.org/obo/GO_1904738 vascular associated smooth muscle cell migration http://purl.obolibrary.org/obo/GO_0014909 smooth muscle cell migration The orderly movement of a vascular associated smooth muscle cell from one site to another. http://purl.obolibrary.org/obo/GO_2000007 negative regulation of metanephric comma-shaped body morphogenesis http://purl.obolibrary.org/obo/GO_2000006 regulation of metanephric comma-shaped body morphogenesis Any process that stops, prevents, or reduces the frequency, rate or extent of metanephric comma-shaped body morphogenesis. http://purl.obolibrary.org/obo/GO_1904749 regulation of protein localization to nucleolus http://purl.obolibrary.org/obo/GO_1900180 regulation of protein localization to nucleus Any process that modulates the frequency, rate or extent of protein localization to nucleolus. http://purl.obolibrary.org/obo/GO_2000061 regulation of ureter smooth muscle cell differentiation http://purl.obolibrary.org/obo/GO_0048634 regulation of muscle organ development Any process that modulates the frequency, rate or extent of ureter smooth muscle cell differentiation. http://purl.obolibrary.org/obo/GO_1904750 negative regulation of protein localization to nucleolus http://purl.obolibrary.org/obo/GO_1900181 negative regulation of protein localization to nucleus Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to nucleolus. http://purl.obolibrary.org/obo/GO_2000062 negative regulation of ureter smooth muscle cell differentiation http://purl.obolibrary.org/obo/GO_2000061 regulation of ureter smooth muscle cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of ureter smooth muscle cell differentiation. http://purl.obolibrary.org/obo/GO_1904751 positive regulation of protein localization to nucleolus http://purl.obolibrary.org/obo/GO_1900182 positive regulation of protein localization to nucleus Any process that activates or increases the frequency, rate or extent of protein localization to nucleolus. http://purl.obolibrary.org/obo/GO_2000063 positive regulation of ureter smooth muscle cell differentiation http://purl.obolibrary.org/obo/GO_2000061 regulation of ureter smooth muscle cell differentiation Any process that activates or increases the frequency, rate or extent of ureter smooth muscle cell differentiation. http://purl.obolibrary.org/obo/GO_1904752 regulation of vascular associated smooth muscle cell migration http://purl.obolibrary.org/obo/GO_0014910 regulation of smooth muscle cell migration Any process that modulates the frequency, rate or extent of vascular associated smooth muscle cell migration. http://purl.obolibrary.org/obo/GO_2000074 regulation of type B pancreatic cell development http://purl.obolibrary.org/obo/GO_0060284 regulation of cell development Any process that modulates the frequency, rate or extent of pancreatic B cell development. http://purl.obolibrary.org/obo/GO_1904753 negative regulation of vascular associated smooth muscle cell migration http://purl.obolibrary.org/obo/GO_0014912 negative regulation of smooth muscle cell migration Any process that stops, prevents or reduces the frequency, rate or extent of vascular associated smooth muscle cell migration. http://purl.obolibrary.org/obo/GO_2000077 negative regulation of type B pancreatic cell development http://purl.obolibrary.org/obo/GO_0010721 negative regulation of cell development Any process that stops, prevents, or reduces the frequency, rate or extent of pancreatic B cell development. http://purl.obolibrary.org/obo/GO_2000078 positive regulation of type B pancreatic cell development http://purl.obolibrary.org/obo/GO_0010720 positive regulation of cell development Any process that activates or increases the frequency, rate or extent of pancreatic B cell development. http://purl.obolibrary.org/obo/GO_1904754 positive regulation of vascular associated smooth muscle cell migration http://purl.obolibrary.org/obo/GO_0014911 positive regulation of smooth muscle cell migration Any process that activates or increases the frequency, rate or extent of vascular associated smooth muscle cell migration. http://purl.obolibrary.org/obo/GO_2000087 regulation of mesonephric glomerulus development http://purl.obolibrary.org/obo/GO_0090192 regulation of glomerulus development Any process that modulates the frequency, rate or extent of mesonephric glomerulus development. http://purl.obolibrary.org/obo/GO_1904760 regulation of myofibroblast differentiation http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the frequency, rate or extent of myofibroblast differentiation. http://purl.obolibrary.org/obo/GO_2000088 negative regulation of mesonephric glomerulus development http://purl.obolibrary.org/obo/GO_0090194 negative regulation of glomerulus development Any process that stops, prevents, or reduces the frequency, rate or extent of mesonephric glomerulus development. http://purl.obolibrary.org/obo/GO_1904761 negative regulation of myofibroblast differentiation http://purl.obolibrary.org/obo/GO_1904760 regulation of myofibroblast differentiation Any process that stops, prevents or reduces the frequency, rate or extent of myofibroblast differentiation. http://purl.obolibrary.org/obo/GO_2000089 positive regulation of mesonephric glomerulus development http://purl.obolibrary.org/obo/GO_0090193 positive regulation of glomerulus development Any process that activates or increases the frequency, rate or extent of mesonephric glomerulus development. http://purl.obolibrary.org/obo/GO_1904762 positive regulation of myofibroblast differentiation http://purl.obolibrary.org/obo/GO_0045597 positive regulation of cell differentiation Any process that activates or increases the frequency, rate or extent of myofibroblast differentiation. http://purl.obolibrary.org/obo/GO_1904770 intramembranous bone morphogenesis http://purl.obolibrary.org/obo/GO_0060349 bone morphogenesis The developmental process by which an intramembranous bone is generated and organized. http://purl.obolibrary.org/obo/GO_2000093 regulation of mesonephric nephron tubule epithelial cell differentiation http://purl.obolibrary.org/obo/GO_0072182 regulation of nephron tubule epithelial cell differentiation Any process that modulates the frequency, rate or extent of mesonephric nephron tubule epithelial cell differentiation. http://purl.obolibrary.org/obo/GO_1904776 regulation of protein localization to cell cortex http://purl.obolibrary.org/obo/GO_1904375 regulation of protein localization to cell periphery Any process that modulates the frequency, rate or extent of protein localization to cell cortex. http://purl.obolibrary.org/obo/GO_2000094 negative regulation of mesonephric nephron tubule epithelial cell differentiation http://purl.obolibrary.org/obo/GO_0072183 negative regulation of nephron tubule epithelial cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of mesonephric nephron tubule epithelial cell differentiation. http://purl.obolibrary.org/obo/GO_1904777 negative regulation of protein localization to cell cortex http://purl.obolibrary.org/obo/GO_1904376 negative regulation of protein localization to cell periphery Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell cortex. http://purl.obolibrary.org/obo/GO_2000109 regulation of macrophage apoptotic process http://purl.obolibrary.org/obo/GO_2000106 regulation of leukocyte apoptotic process Any process that modulates the frequency, rate or extent of macrophage apoptotic process. http://purl.obolibrary.org/obo/GO_1904778 positive regulation of protein localization to cell cortex http://purl.obolibrary.org/obo/GO_1904377 positive regulation of protein localization to cell periphery Any process that activates or increases the frequency, rate or extent of protein localization to cell cortex. http://purl.obolibrary.org/obo/GO_2000110 negative regulation of macrophage apoptotic process http://purl.obolibrary.org/obo/GO_2000109 regulation of macrophage apoptotic process Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage apoptotic process. http://purl.obolibrary.org/obo/GO_1904817 serous membrane development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of a serous membrane over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_2000111 positive regulation of macrophage apoptotic process http://purl.obolibrary.org/obo/GO_2000109 regulation of macrophage apoptotic process Any process that activates or increases the frequency, rate or extent of macrophage apoptotic process. http://purl.obolibrary.org/obo/GO_2000155 positive regulation of cilium-dependent cell motility http://purl.obolibrary.org/obo/GO_1902019 regulation of cilium-dependent cell motility Any process that activates or increases the frequency, rate or extent of cilium-dependent cell motility. http://purl.obolibrary.org/obo/GO_1904818 visceral peritoneum development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of a visceral peritoneum over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_2000173 negative regulation of branching morphogenesis of a nerve http://purl.obolibrary.org/obo/GO_0051241 negative regulation of multicellular organismal process Any process that stops, prevents, or reduces the frequency, rate or extent of branching morphogenesis of a nerve. http://purl.obolibrary.org/obo/GO_1904819 parietal peritoneum development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of a parietal peritoneum over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_2000174 regulation of pro-T cell differentiation http://purl.obolibrary.org/obo/GO_0045580 regulation of T cell differentiation Any process that modulates the frequency, rate or extent of pro-T cell differentiation. http://purl.obolibrary.org/obo/GO_1904820 peritoneum development http://purl.obolibrary.org/obo/GO_1904817 serous membrane development The process whose specific outcome is the progression of a peritoneum over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_2000175 negative regulation of pro-T cell differentiation http://purl.obolibrary.org/obo/GO_2000174 regulation of pro-T cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of pro-T cell differentiation. http://purl.obolibrary.org/obo/GO_1904821 chloroplast disassembly http://purl.obolibrary.org/obo/GO_0009658 chloroplast organization The disaggregation of a chloroplast into its constituent components. http://purl.obolibrary.org/obo/GO_1904829 regulation of aortic smooth muscle cell differentiation http://purl.obolibrary.org/obo/GO_1905063 regulation of vascular associated smooth muscle cell differentiation Any process that modulates the frequency, rate or extent of aortic smooth muscle cell differentiation. http://purl.obolibrary.org/obo/GO_2000176 positive regulation of pro-T cell differentiation http://purl.obolibrary.org/obo/GO_2000174 regulation of pro-T cell differentiation Any process that activates or increases the frequency, rate or extent of pro-T cell differentiation. http://purl.obolibrary.org/obo/GO_1904830 negative regulation of aortic smooth muscle cell differentiation http://purl.obolibrary.org/obo/GO_1905064 negative regulation of vascular associated smooth muscle cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of aortic smooth muscle cell differentiation. http://purl.obolibrary.org/obo/GO_2000182 regulation of progesterone biosynthetic process http://purl.obolibrary.org/obo/GO_0050810 regulation of steroid biosynthetic process Any process that modulates the frequency, rate or extent of progesterone biosynthetic process. http://purl.obolibrary.org/obo/GO_1904831 positive regulation of aortic smooth muscle cell differentiation http://purl.obolibrary.org/obo/GO_1905065 positive regulation of vascular associated smooth muscle cell differentiation Any process that activates or increases the frequency, rate or extent of aortic smooth muscle cell differentiation. http://purl.obolibrary.org/obo/GO_2000184 positive regulation of progesterone biosynthetic process http://purl.obolibrary.org/obo/GO_0046886 positive regulation of hormone biosynthetic process Any process that activates or increases the frequency, rate or extent of progesterone biosynthetic process. http://purl.obolibrary.org/obo/GO_2000185 regulation of phosphate transmembrane transport http://purl.obolibrary.org/obo/GO_0010966 regulation of phosphate transport Any process that modulates the frequency, rate or extent of phosphate transmembrane transport. http://purl.obolibrary.org/obo/GO_1904835 dorsal root ganglion morphogenesis http://purl.obolibrary.org/obo/GO_0061552 ganglion morphogenesis The developmental process by which a dorsal root ganglion is generated and organized. http://purl.obolibrary.org/obo/GO_2000186 negative regulation of phosphate transmembrane transport http://purl.obolibrary.org/obo/GO_2000185 regulation of phosphate transmembrane transport Any process that stops, prevents, or reduces the frequency, rate or extent of phosphate transmembrane transport. http://purl.obolibrary.org/obo/GO_1904836 facioacoustic ganglion morphogenesis http://purl.obolibrary.org/obo/GO_0061559 cranial ganglion morphogenesis The developmental process by which an acoustico-facial VII-VIII ganglion complex is generated and organized. http://purl.obolibrary.org/obo/GO_1904838 regulation of male germ-line stem cell asymmetric division http://purl.obolibrary.org/obo/GO_0009786 regulation of asymmetric cell division Any process that modulates the frequency, rate or extent of male germ-line stem cell asymmetric division. http://purl.obolibrary.org/obo/GO_2000187 positive regulation of phosphate transmembrane transport http://purl.obolibrary.org/obo/GO_2000185 regulation of phosphate transmembrane transport Any process that activates or increases the frequency, rate or extent of phosphate transmembrane transport. http://purl.obolibrary.org/obo/GO_1904839 negative regulation of male germ-line stem cell asymmetric division http://purl.obolibrary.org/obo/GO_0010721 negative regulation of cell development Any process that stops, prevents or reduces the frequency, rate or extent of male germ-line stem cell asymmetric division. http://purl.obolibrary.org/obo/GO_2000194 regulation of female gonad development http://purl.obolibrary.org/obo/GO_1905939 regulation of gonad development Any process that modulates the frequency, rate or extent of female gonad development. http://purl.obolibrary.org/obo/GO_1904840 positive regulation of male germ-line stem cell asymmetric division http://purl.obolibrary.org/obo/GO_0045770 positive regulation of asymmetric cell division Any process that activates or increases the frequency, rate or extent of male germ-line stem cell asymmetric division. http://purl.obolibrary.org/obo/GO_2000195 negative regulation of female gonad development http://purl.obolibrary.org/obo/GO_2000194 regulation of female gonad development Any process that stops, prevents, or reduces the frequency, rate or extent of female gonad development. http://purl.obolibrary.org/obo/GO_1904866 ventral tegmental area development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of a ventral tegmental area (VTA) over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_2000196 positive regulation of female gonad development http://purl.obolibrary.org/obo/GO_2000194 regulation of female gonad development Any process that activates or increases the frequency, rate or extent of female gonad development. http://purl.obolibrary.org/obo/GO_1904889 regulation of excitatory synapse assembly http://purl.obolibrary.org/obo/GO_0051963 regulation of synapse assembly Any process that modulates the frequency, rate or extent of excitatory synapse assembly. http://purl.obolibrary.org/obo/GO_1904890 negative regulation of excitatory synapse assembly http://purl.obolibrary.org/obo/GO_1904889 regulation of excitatory synapse assembly Any process that stops, prevents or reduces the frequency, rate or extent of excitatory synapse assembly. http://purl.obolibrary.org/obo/GO_1904891 positive regulation of excitatory synapse assembly http://purl.obolibrary.org/obo/GO_1904889 regulation of excitatory synapse assembly Any process that activates or increases the frequency, rate or extent of excitatory synapse assembly. http://purl.obolibrary.org/obo/GO_2000198 negative regulation of ribonucleoprotein complex localization http://purl.obolibrary.org/obo/GO_2000197 regulation of ribonucleoprotein complex localization Any process that stops, prevents, or reduces the frequency, rate or extent of ribonucleoprotein complex localization. http://purl.obolibrary.org/obo/GO_1904897 regulation of hepatic stellate cell proliferation http://purl.obolibrary.org/obo/GO_0048145 regulation of fibroblast proliferation Any process that modulates the frequency, rate or extent of hepatic stellate cell proliferation. http://purl.obolibrary.org/obo/GO_2000199 positive regulation of ribonucleoprotein complex localization http://purl.obolibrary.org/obo/GO_2000197 regulation of ribonucleoprotein complex localization Any process that activates or increases the frequency, rate or extent of ribonucleoprotein complex localization. http://purl.obolibrary.org/obo/GO_1904898 negative regulation of hepatic stellate cell proliferation http://purl.obolibrary.org/obo/GO_1904897 regulation of hepatic stellate cell proliferation Any process that stops, prevents or reduces the frequency, rate or extent of hepatic stellate cell proliferation. http://purl.obolibrary.org/obo/GO_2000224 regulation of testosterone biosynthetic process http://purl.obolibrary.org/obo/GO_0050810 regulation of steroid biosynthetic process Any process that modulates the frequency, rate or extent of testosterone biosynthetic process. http://purl.obolibrary.org/obo/GO_1904899 positive regulation of hepatic stellate cell proliferation http://purl.obolibrary.org/obo/GO_1904897 regulation of hepatic stellate cell proliferation Any process that activates or increases the frequency, rate or extent of hepatic stellate cell proliferation. http://purl.obolibrary.org/obo/GO_1904933 regulation of cell proliferation in midbrain http://purl.obolibrary.org/obo/GO_2000177 regulation of neural precursor cell proliferation Any process that modulates the frequency, rate or extent of cell proliferation in midbrain. http://purl.obolibrary.org/obo/GO_2000225 negative regulation of testosterone biosynthetic process http://purl.obolibrary.org/obo/GO_0010894 negative regulation of steroid biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of testosterone biosynthetic process. http://purl.obolibrary.org/obo/GO_1904934 negative regulation of cell proliferation in midbrain http://purl.obolibrary.org/obo/GO_1904933 regulation of cell proliferation in midbrain Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation in midbrain. http://purl.obolibrary.org/obo/GO_2000226 regulation of pancreatic A cell differentiation http://purl.obolibrary.org/obo/GO_0030856 regulation of epithelial cell differentiation Any process that modulates the frequency, rate or extent of pancreatic A cell differentiation. http://purl.obolibrary.org/obo/GO_1904935 positive regulation of cell proliferation in midbrain http://purl.obolibrary.org/obo/GO_2000179 positive regulation of neural precursor cell proliferation Any process that activates or increases the frequency, rate or extent of cell proliferation in midbrain. http://purl.obolibrary.org/obo/GO_2000227 negative regulation of pancreatic A cell differentiation http://purl.obolibrary.org/obo/GO_2000226 regulation of pancreatic A cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of pancreatic A cell differentiation. http://purl.obolibrary.org/obo/GO_1904937 sensory neuron migration http://purl.obolibrary.org/obo/GO_0001764 neuron migration The orderly movement of a sensory neuron from one site to another. http://purl.obolibrary.org/obo/GO_2000228 positive regulation of pancreatic A cell differentiation http://purl.obolibrary.org/obo/GO_2000226 regulation of pancreatic A cell differentiation Any process that activates or increases the frequency, rate or extent of pancreatic A cell differentiation. http://purl.obolibrary.org/obo/GO_1904942 regulation of cardiac ventricle formation http://purl.obolibrary.org/obo/GO_1901210 regulation of cardiac chamber formation Any process that modulates the frequency, rate or extent of cardiac ventricle formation. http://purl.obolibrary.org/obo/GO_2000229 regulation of pancreatic stellate cell proliferation http://purl.obolibrary.org/obo/GO_0048145 regulation of fibroblast proliferation Any process that modulates the frequency, rate or extent of pancreatic stellate cell proliferation. http://purl.obolibrary.org/obo/GO_1904943 negative regulation of cardiac ventricle formation http://purl.obolibrary.org/obo/GO_1901211 negative regulation of cardiac chamber formation Any process that stops, prevents or reduces the frequency, rate or extent of cardiac ventricle formation. http://purl.obolibrary.org/obo/GO_2000230 negative regulation of pancreatic stellate cell proliferation http://purl.obolibrary.org/obo/GO_2000229 regulation of pancreatic stellate cell proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of pancreatic stellate cell proliferation. http://purl.obolibrary.org/obo/GO_1904944 positive regulation of cardiac ventricle formation http://purl.obolibrary.org/obo/GO_1901212 positive regulation of cardiac chamber formation Any process that activates or increases the frequency, rate or extent of cardiac ventricle formation. http://purl.obolibrary.org/obo/GO_2000231 positive regulation of pancreatic stellate cell proliferation http://purl.obolibrary.org/obo/GO_2000229 regulation of pancreatic stellate cell proliferation Any process that activates or increases the frequency, rate or extent of pancreatic stellate cell proliferation. http://purl.obolibrary.org/obo/GO_1904948 midbrain dopaminergic neuron differentiation http://purl.obolibrary.org/obo/GO_0071542 dopaminergic neuron differentiation The process in which a relatively unspecialized cell acquires the specialized features of a midbrain dopaminergic neuron. http://purl.obolibrary.org/obo/GO_2000238 regulation of tRNA export from nucleus http://purl.obolibrary.org/obo/GO_2000197 regulation of ribonucleoprotein complex localization Any process that modulates the frequency, rate or extent of tRNA export from nucleus. http://purl.obolibrary.org/obo/GO_1904956 regulation of midbrain dopaminergic neuron differentiation http://purl.obolibrary.org/obo/GO_1904338 regulation of dopaminergic neuron differentiation Any process that modulates the frequency, rate or extent of midbrain dopaminergic neuron differentiation. http://purl.obolibrary.org/obo/GO_2000239 negative regulation of tRNA export from nucleus http://purl.obolibrary.org/obo/GO_2000238 regulation of tRNA export from nucleus Any process that stops, prevents, or reduces the frequency, rate or extent of tRNA export from nucleus. http://purl.obolibrary.org/obo/GO_1904957 negative regulation of midbrain dopaminergic neuron differentiation http://purl.obolibrary.org/obo/GO_1904956 regulation of midbrain dopaminergic neuron differentiation Any process that stops, prevents or reduces the frequency, rate or extent of midbrain dopaminergic neuron differentiation. http://purl.obolibrary.org/obo/GO_2000240 positive regulation of tRNA export from nucleus http://purl.obolibrary.org/obo/GO_2000238 regulation of tRNA export from nucleus Any process that activates or increases the frequency, rate or extent of tRNA export from nucleus. http://purl.obolibrary.org/obo/GO_1904958 positive regulation of midbrain dopaminergic neuron differentiation http://purl.obolibrary.org/obo/GO_1904956 regulation of midbrain dopaminergic neuron differentiation Any process that activates or increases the frequency, rate or extent of midbrain dopaminergic neuron differentiation. http://purl.obolibrary.org/obo/GO_2000248 negative regulation of establishment or maintenance of neuroblast polarity http://purl.obolibrary.org/obo/GO_0010454 negative regulation of cell fate commitment Any process that stops, prevents, or reduces the frequency, rate or extent of establishment or maintenance of neuroblast polarity. http://purl.obolibrary.org/obo/GO_1904962 plastid to vacuole vesicle-mediated transport http://purl.obolibrary.org/obo/GO_0016482 cytosolic transport The vesicle-mediated and directed movement of substances from plastid to vacuole. http://purl.obolibrary.org/obo/GO_2000254 regulation of male germ cell proliferation http://purl.obolibrary.org/obo/GO_1905936 regulation of germ cell proliferation Any process that modulates the frequency, rate or extent of male germ cell proliferation. http://purl.obolibrary.org/obo/GO_1904969 slow muscle cell migration http://purl.obolibrary.org/obo/GO_0110122 myotube cell migration The orderly movement of a slow muscle cell from one site to another. http://purl.obolibrary.org/obo/GO_2000255 negative regulation of male germ cell proliferation http://purl.obolibrary.org/obo/GO_2000242 negative regulation of reproductive process Any process that stops, prevents or reduces the frequency, rate or extent of male germ cell proliferation. http://purl.obolibrary.org/obo/GO_1904977 lymphatic endothelial cell migration http://purl.obolibrary.org/obo/GO_0043542 endothelial cell migration The orderly movement of a lymphatic endothelial cell from one site to another in the wall of a lymphatic vessel. http://purl.obolibrary.org/obo/GO_2000256 positive regulation of male germ cell proliferation http://purl.obolibrary.org/obo/GO_2000243 positive regulation of reproductive process Any process that activates or increases the frequency, rate or extent of male germ cell proliferation. http://purl.obolibrary.org/obo/GO_1904983 glycine import into mitochondrion http://purl.obolibrary.org/obo/GO_0170036 import into the mitochondrion The process in which glycine is transported from the cytosol into the mitochondrial matrix. http://purl.obolibrary.org/obo/GO_2000269 regulation of fibroblast apoptotic process http://purl.obolibrary.org/obo/GO_0042981 regulation of apoptotic process Any process that modulates the frequency, rate or extent of fibroblast apoptotic process. http://purl.obolibrary.org/obo/GO_2000270 negative regulation of fibroblast apoptotic process http://purl.obolibrary.org/obo/GO_2000269 regulation of fibroblast apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of fibroblast apoptotic process. http://purl.obolibrary.org/obo/GO_1904987 regulation of endothelial cell activation http://purl.obolibrary.org/obo/GO_0050865 regulation of cell activation Any process that modulates the frequency, rate or extent of endothelial cell activation. http://purl.obolibrary.org/obo/GO_2000271 positive regulation of fibroblast apoptotic process http://purl.obolibrary.org/obo/GO_0043065 positive regulation of apoptotic process Any process that activates or increases the frequency, rate or extent of fibroblast apoptotic process. http://purl.obolibrary.org/obo/GO_1904988 negative regulation of endothelial cell activation http://purl.obolibrary.org/obo/GO_0050866 negative regulation of cell activation Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell activation. http://purl.obolibrary.org/obo/GO_2000287 positive regulation of myotome development http://purl.obolibrary.org/obo/GO_2000290 regulation of myotome development Any process that activates or increases the frequency, rate or extent of myotome development. http://purl.obolibrary.org/obo/GO_1904989 positive regulation of endothelial cell activation http://purl.obolibrary.org/obo/GO_0050867 positive regulation of cell activation Any process that activates or increases the frequency, rate or extent of endothelial cell activation. http://purl.obolibrary.org/obo/GO_1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_0060372 regulation of atrial cardiac muscle cell membrane repolarization Any process that modulates the frequency, rate or extent of membrane repolarization during atrial cardiac muscle cell action potential. http://purl.obolibrary.org/obo/GO_2000288 positive regulation of myoblast proliferation http://purl.obolibrary.org/obo/GO_2000291 regulation of myoblast proliferation Any process that activates or increases the frequency, rate or extent of myoblast proliferation. http://purl.obolibrary.org/obo/GO_1905001 negative regulation of membrane repolarization during atrial cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_1905032 negative regulation of membrane repolarization during cardiac muscle cell action potential Any process that stops, prevents or reduces the frequency, rate or extent of membrane repolarization during atrial cardiac muscle cell action potential. http://purl.obolibrary.org/obo/GO_2000290 regulation of myotome development http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of myotome development. http://purl.obolibrary.org/obo/GO_1905002 positive regulation of membrane repolarization during atrial cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_1905033 positive regulation of membrane repolarization during cardiac muscle cell action potential Any process that activates or increases the frequency, rate or extent of membrane repolarization during atrial cardiac muscle cell action potential. http://purl.obolibrary.org/obo/GO_1905011 transmembrane phosphate ion transport from cytosol to vacuole http://purl.obolibrary.org/obo/GO_0035435 phosphate ion transmembrane transport The directed movement of phosphate ions from the cytosol across the vacuolar membrane and into the vacuolar lumen. http://purl.obolibrary.org/obo/GO_2000291 regulation of myoblast proliferation http://purl.obolibrary.org/obo/GO_0042127 regulation of cell population proliferation Any process that modulates the frequency, rate or extent of myoblast proliferation. http://purl.obolibrary.org/obo/GO_1905024 regulation of membrane repolarization during ventricular cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_0060307 regulation of ventricular cardiac muscle cell membrane repolarization Any process that modulates the frequency, rate or extent of membrane repolarization during ventricular cardiac muscle cell action potential. http://purl.obolibrary.org/obo/GO_2000292 regulation of defecation http://purl.obolibrary.org/obo/GO_0044062 regulation of excretion Any process that modulates the frequency, rate or extent of defecation. http://purl.obolibrary.org/obo/GO_1905025 negative regulation of membrane repolarization during ventricular cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_1905032 negative regulation of membrane repolarization during cardiac muscle cell action potential Any process that stops, prevents or reduces the frequency, rate or extent of membrane repolarization during ventricular cardiac muscle cell action potential. http://purl.obolibrary.org/obo/GO_2000293 negative regulation of defecation http://purl.obolibrary.org/obo/GO_0060457 negative regulation of digestive system process Any process that stops, prevents or reduces the frequency, rate or extent of defecation. http://purl.obolibrary.org/obo/GO_1905026 positive regulation of membrane repolarization during ventricular cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_1905033 positive regulation of membrane repolarization during cardiac muscle cell action potential Any process that activates or increases the frequency, rate or extent of membrane repolarization during ventricular cardiac muscle cell action potential. http://purl.obolibrary.org/obo/GO_2000294 positive regulation of defecation http://purl.obolibrary.org/obo/GO_2000292 regulation of defecation Any process that activates or increases the frequency, rate or extent of defecation. http://purl.obolibrary.org/obo/GO_1905027 regulation of membrane depolarization during AV node cell action potential http://purl.obolibrary.org/obo/GO_1900825 regulation of membrane depolarization during cardiac muscle cell action potential Any process that modulates the frequency, rate or extent of membrane depolarization during AV node cell action potential. http://purl.obolibrary.org/obo/GO_2000316 regulation of T-helper 17 type immune response http://purl.obolibrary.org/obo/GO_0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains Any process that modulates the frequency, rate or extent of T-helper 17 type immune response. http://purl.obolibrary.org/obo/GO_1905028 negative regulation of membrane depolarization during AV node cell action potential http://purl.obolibrary.org/obo/GO_1900826 negative regulation of membrane depolarization during cardiac muscle cell action potential Any process that stops, prevents or reduces the frequency, rate or extent of membrane depolarization during AV node cell action potential. http://purl.obolibrary.org/obo/GO_2000317 negative regulation of T-helper 17 type immune response http://purl.obolibrary.org/obo/GO_2000316 regulation of T-helper 17 type immune response Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 17 type immune response. http://purl.obolibrary.org/obo/GO_1905029 positive regulation of membrane depolarization during AV node cell action potential http://purl.obolibrary.org/obo/GO_1900827 positive regulation of membrane depolarization during cardiac muscle cell action potential Any process that activates or increases the frequency, rate or extent of membrane depolarization during AV node cell action potential. http://purl.obolibrary.org/obo/GO_2000318 positive regulation of T-helper 17 type immune response http://purl.obolibrary.org/obo/GO_2000316 regulation of T-helper 17 type immune response Any process that activates or increases the frequency, rate or extent of T-helper 17 type immune response. http://purl.obolibrary.org/obo/GO_1905031 regulation of membrane repolarization during cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_0099623 regulation of cardiac muscle cell membrane repolarization Any process that modulates the frequency, rate or extent of membrane repolarization during cardiac muscle cell action potential. http://purl.obolibrary.org/obo/GO_2000319 regulation of T-helper 17 cell differentiation http://purl.obolibrary.org/obo/GO_2000316 regulation of T-helper 17 type immune response Any process that modulates the frequency, rate or extent of T-helper 17 cell differentiation. http://purl.obolibrary.org/obo/GO_1905032 negative regulation of membrane repolarization during cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_0048519 negative regulation of biological process Any process that stops, prevents or reduces the frequency, rate or extent of membrane repolarization during cardiac muscle cell action potential. http://purl.obolibrary.org/obo/GO_2000320 negative regulation of T-helper 17 cell differentiation http://purl.obolibrary.org/obo/GO_2000319 regulation of T-helper 17 cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 17 cell differentiation. http://purl.obolibrary.org/obo/GO_1905033 positive regulation of membrane repolarization during cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_0048518 positive regulation of biological process Any process that activates or increases the frequency, rate or extent of membrane repolarization during cardiac muscle cell action potential. http://purl.obolibrary.org/obo/GO_2000321 positive regulation of T-helper 17 cell differentiation http://purl.obolibrary.org/obo/GO_2000319 regulation of T-helper 17 cell differentiation Any process that activates or increases the frequency, rate or extent of T-helper 17 cell differentiation. http://purl.obolibrary.org/obo/GO_1905040 otic placode development http://purl.obolibrary.org/obo/GO_0071696 ectodermal placode development The process whose specific outcome is the progression of an otic placode over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_2000345 regulation of hepatocyte proliferation http://purl.obolibrary.org/obo/GO_0050678 regulation of epithelial cell proliferation Any process that modulates the frequency, rate or extent of hepatocyte proliferation. http://purl.obolibrary.org/obo/GO_1905063 regulation of vascular associated smooth muscle cell differentiation http://purl.obolibrary.org/obo/GO_0051150 regulation of smooth muscle cell differentiation Any process that modulates the frequency, rate or extent of vascular smooth muscle cell differentiation. http://purl.obolibrary.org/obo/GO_2000346 negative regulation of hepatocyte proliferation http://purl.obolibrary.org/obo/GO_2000345 regulation of hepatocyte proliferation Any process that stops, prevents or reduces the frequency, rate or extent of hepatocyte proliferation. http://purl.obolibrary.org/obo/GO_1905064 negative regulation of vascular associated smooth muscle cell differentiation http://purl.obolibrary.org/obo/GO_1905063 regulation of vascular associated smooth muscle cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle cell differentiation. http://purl.obolibrary.org/obo/GO_2000347 positive regulation of hepatocyte proliferation http://purl.obolibrary.org/obo/GO_2000345 regulation of hepatocyte proliferation Any process that activates or increases the frequency, rate or extent of hepatocyte proliferation. http://purl.obolibrary.org/obo/GO_1905065 positive regulation of vascular associated smooth muscle cell differentiation http://purl.obolibrary.org/obo/GO_1905063 regulation of vascular associated smooth muscle cell differentiation Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell differentiation. http://purl.obolibrary.org/obo/GO_2000351 regulation of endothelial cell apoptotic process http://purl.obolibrary.org/obo/GO_0042981 regulation of apoptotic process Any process that modulates the frequency, rate or extent of endothelial cell apoptotic process. http://purl.obolibrary.org/obo/GO_1905069 allantois development http://purl.obolibrary.org/obo/GO_1903867 extraembryonic membrane development The process whose specific outcome is the progression of an allantois over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_2000352 negative regulation of endothelial cell apoptotic process http://purl.obolibrary.org/obo/GO_2000351 regulation of endothelial cell apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell apoptotic process. http://purl.obolibrary.org/obo/GO_1905070 anterior visceral endoderm cell migration http://purl.obolibrary.org/obo/GO_0016477 cell migration The orderly movement of an anterior visceral endoderm cell from one site to another. http://purl.obolibrary.org/obo/GO_2000353 positive regulation of endothelial cell apoptotic process http://purl.obolibrary.org/obo/GO_0043065 positive regulation of apoptotic process Any process that activates or increases the frequency, rate or extent of endothelial cell apoptotic process. http://purl.obolibrary.org/obo/GO_1905071 tight junction disassembly http://purl.obolibrary.org/obo/GO_0150147 cell-cell junction disassembly The disaggregation of an tight junction into its constituent components. http://purl.obolibrary.org/obo/GO_2000354 regulation of ovarian follicle development http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of ovarian follicle development. http://purl.obolibrary.org/obo/GO_1905073 regulation of tight junction disassembly http://purl.obolibrary.org/obo/GO_0051128 regulation of cellular component organization Any process that modulates the frequency, rate or extent of tight junction disassembly. http://purl.obolibrary.org/obo/GO_2000374 regulation of oxygen metabolic process http://purl.obolibrary.org/obo/GO_0019222 regulation of metabolic process Any process that modulates the frequency, rate or extent of oxygen metabolic process. http://purl.obolibrary.org/obo/GO_1905074 negative regulation of tight junction disassembly http://purl.obolibrary.org/obo/GO_0051129 negative regulation of cellular component organization Any process that stops, prevents or reduces the frequency, rate or extent of tight junction disassembly. http://purl.obolibrary.org/obo/GO_2000385 positive regulation of ectoderm development http://purl.obolibrary.org/obo/GO_2000383 regulation of ectoderm development Any process that activates or increases the frequency, rate or extent of ectoderm development. http://purl.obolibrary.org/obo/GO_1905075 positive regulation of tight junction disassembly http://purl.obolibrary.org/obo/GO_0051130 positive regulation of cellular component organization Any process that activates or increases the frequency, rate or extent of tight junction disassembly. http://purl.obolibrary.org/obo/GO_2000386 positive regulation of ovarian follicle development http://purl.obolibrary.org/obo/GO_2000354 regulation of ovarian follicle development Any process that activates or increases the frequency, rate or extent of ovarian follicle development. http://purl.obolibrary.org/obo/GO_1905079 regulation of cerebellar neuron development http://purl.obolibrary.org/obo/GO_0060284 regulation of cell development Any process that modulates the frequency, rate or extent of cerebellar neuron development. http://purl.obolibrary.org/obo/GO_2000403 positive regulation of lymphocyte migration http://purl.obolibrary.org/obo/GO_0071677 positive regulation of mononuclear cell migration Any process that activates or increases the frequency, rate or extent of lymphocyte migration. http://purl.obolibrary.org/obo/GO_1905080 negative regulation of cerebellar neuron development http://purl.obolibrary.org/obo/GO_0045665 negative regulation of neuron differentiation Any process that stops, prevents or reduces the frequency, rate or extent of cerebellar neuron development. http://purl.obolibrary.org/obo/GO_2000405 negative regulation of T cell migration http://purl.obolibrary.org/obo/GO_2000404 regulation of T cell migration Any process that stops, prevents or reduces the frequency, rate or extent of T cell migration. http://purl.obolibrary.org/obo/GO_1905081 positive regulation of cerebellar neuron development http://purl.obolibrary.org/obo/GO_0045666 positive regulation of neuron differentiation Any process that activates or increases the frequency, rate or extent of cerebellar neuron development. http://purl.obolibrary.org/obo/GO_2000410 regulation of thymocyte migration http://purl.obolibrary.org/obo/GO_2000404 regulation of T cell migration Any process that modulates the frequency, rate or extent of thymocyte migration. http://purl.obolibrary.org/obo/GO_1905082 regulation of mitochondrial translational elongation http://purl.obolibrary.org/obo/GO_0006448 regulation of translational elongation Any process that modulates the frequency, rate or extent of mitochondrial translational elongation. http://purl.obolibrary.org/obo/GO_2000411 negative regulation of thymocyte migration http://purl.obolibrary.org/obo/GO_2000410 regulation of thymocyte migration Any process that stops, prevents or reduces the frequency, rate or extent of thymocyte migration. http://purl.obolibrary.org/obo/GO_1905083 negative regulation of mitochondrial translational elongation http://purl.obolibrary.org/obo/GO_0070130 negative regulation of mitochondrial translation Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial translational elongation. http://purl.obolibrary.org/obo/GO_2000412 positive regulation of thymocyte migration http://purl.obolibrary.org/obo/GO_2000406 positive regulation of T cell migration Any process that activates or increases the frequency, rate or extent of thymocyte migration. http://purl.obolibrary.org/obo/GO_1905084 positive regulation of mitochondrial translational elongation http://purl.obolibrary.org/obo/GO_1905082 regulation of mitochondrial translational elongation Any process that activates or increases the frequency, rate or extent of mitochondrial translational elongation. http://purl.obolibrary.org/obo/GO_2000416 regulation of eosinophil migration http://purl.obolibrary.org/obo/GO_0002685 regulation of leukocyte migration Any process that modulates the frequency, rate or extent of eosinophil migration. http://purl.obolibrary.org/obo/GO_1905109 regulation of pulmonary blood vessel remodeling http://purl.obolibrary.org/obo/GO_0060312 regulation of blood vessel remodeling Any process that modulates the frequency, rate or extent of pulmonary blood vessel remodeling. http://purl.obolibrary.org/obo/GO_2000417 negative regulation of eosinophil migration http://purl.obolibrary.org/obo/GO_2000416 regulation of eosinophil migration Any process that stops, prevents or reduces the frequency, rate or extent of eosinophil migration. http://purl.obolibrary.org/obo/GO_1905110 negative regulation of pulmonary blood vessel remodeling http://purl.obolibrary.org/obo/GO_0060313 negative regulation of blood vessel remodeling Any process that stops, prevents or reduces the frequency, rate or extent of pulmonary blood vessel remodeling. http://purl.obolibrary.org/obo/GO_2000418 positive regulation of eosinophil migration http://purl.obolibrary.org/obo/GO_2000416 regulation of eosinophil migration Any process that activates or increases the frequency, rate or extent of eosinophil migration. http://purl.obolibrary.org/obo/GO_1905111 positive regulation of pulmonary blood vessel remodeling http://purl.obolibrary.org/obo/GO_2000504 positive regulation of blood vessel remodeling Any process that activates or increases the frequency, rate or extent of pulmonary blood vessel remodeling. http://purl.obolibrary.org/obo/GO_2000422 regulation of eosinophil chemotaxis http://purl.obolibrary.org/obo/GO_0071622 regulation of granulocyte chemotaxis Any process that modulates the frequency, rate or extent of eosinophil chemotaxis. http://purl.obolibrary.org/obo/GO_1905126 regulation of axo-dendritic protein transport http://purl.obolibrary.org/obo/GO_0033157 regulation of intracellular protein transport Any process that modulates the frequency, rate or extent of axo-dendritic protein transport. http://purl.obolibrary.org/obo/GO_2000423 negative regulation of eosinophil chemotaxis http://purl.obolibrary.org/obo/GO_0071623 negative regulation of granulocyte chemotaxis Any process that stops, prevents or reduces the frequency, rate or extent of eosinophil chemotaxis. http://purl.obolibrary.org/obo/GO_1905127 negative regulation of axo-dendritic protein transport http://purl.obolibrary.org/obo/GO_0090317 negative regulation of intracellular protein transport Any process that stops, prevents or reduces the frequency, rate or extent of axo-dendritic protein transport. http://purl.obolibrary.org/obo/GO_2000424 positive regulation of eosinophil chemotaxis http://purl.obolibrary.org/obo/GO_0071624 positive regulation of granulocyte chemotaxis Any process that activates or increases the frequency, rate or extent of eosinophil chemotaxis. http://purl.obolibrary.org/obo/GO_2000458 regulation of astrocyte chemotaxis http://purl.obolibrary.org/obo/GO_1903975 regulation of glial cell migration Any process that modulates the frequency, rate or extent of astrocyte chemotaxis. http://purl.obolibrary.org/obo/GO_1905128 positive regulation of axo-dendritic protein transport http://purl.obolibrary.org/obo/GO_0090316 positive regulation of intracellular protein transport Any process that activates or increases the frequency, rate or extent of axo-dendritic protein transport. http://purl.obolibrary.org/obo/GO_2000459 negative regulation of astrocyte chemotaxis http://purl.obolibrary.org/obo/GO_2000458 regulation of astrocyte chemotaxis Any process that stops, prevents or reduces the frequency, rate or extent of astrocyte chemotaxis. http://purl.obolibrary.org/obo/GO_1905139 apical ectodermal ridge formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process that gives rise to the apical ectodermal ridge. This process pertains to the initial formation of a structure from unspecified parts. http://purl.obolibrary.org/obo/GO_2000463 positive regulation of excitatory postsynaptic potential http://purl.obolibrary.org/obo/GO_0098815 modulation of excitatory postsynaptic potential Any process that enhances the establishment or increases the extent of the excitatory postsynaptic potential (EPSP) which is a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential. http://purl.obolibrary.org/obo/GO_1905140 regulation of apical ectodermal ridge formation http://purl.obolibrary.org/obo/GO_0022603 regulation of anatomical structure morphogenesis Any process that modulates the frequency, rate or extent of apical ectodermal ridge formation. http://purl.obolibrary.org/obo/GO_2000464 positive regulation of astrocyte chemotaxis http://purl.obolibrary.org/obo/GO_2000458 regulation of astrocyte chemotaxis Any process that activates or increases the frequency, rate or extent of astrocyte chemotaxis. http://purl.obolibrary.org/obo/GO_1905141 negative regulation of apical ectodermal ridge formation http://purl.obolibrary.org/obo/GO_0051241 negative regulation of multicellular organismal process Any process that stops, prevents or reduces the frequency, rate or extent of apical ectodermal ridge formation. http://purl.obolibrary.org/obo/GO_2000471 regulation of hematopoietic stem cell migration http://purl.obolibrary.org/obo/GO_0030334 regulation of cell migration Any process that modulates the frequency, rate or extent of hematopoietic stem cell migration. http://purl.obolibrary.org/obo/GO_1905142 positive regulation of apical ectodermal ridge formation http://purl.obolibrary.org/obo/GO_0051240 positive regulation of multicellular organismal process Any process that activates or increases the frequency, rate or extent of apical ectodermal ridge formation. http://purl.obolibrary.org/obo/GO_2000472 negative regulation of hematopoietic stem cell migration http://purl.obolibrary.org/obo/GO_2000471 regulation of hematopoietic stem cell migration Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic stem cell migration. http://purl.obolibrary.org/obo/GO_1905144 response to acetylcholine http://purl.obolibrary.org/obo/GO_1901698 response to nitrogen compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetylcholine stimulus. http://purl.obolibrary.org/obo/GO_2000473 positive regulation of hematopoietic stem cell migration http://purl.obolibrary.org/obo/GO_2000471 regulation of hematopoietic stem cell migration Any process that activates or increases the frequency, rate or extent of hematopoietic stem cell migration. http://purl.obolibrary.org/obo/GO_1905146 lysosomal protein catabolic process http://purl.obolibrary.org/obo/GO_0007039 protein catabolic process in the vacuole Any cellular protein catabolic process that takes place in a lysosome. http://purl.obolibrary.org/obo/GO_2000477 regulation of metanephric podocyte development http://purl.obolibrary.org/obo/GO_0060284 regulation of cell development Any process that modulates the frequency, rate or extent of metanephric glomerular visceral epithelial cell development. http://purl.obolibrary.org/obo/GO_1905147 regulation of smooth muscle hypertrophy http://purl.obolibrary.org/obo/GO_0043502 regulation of muscle adaptation Any process that modulates the frequency, rate or extent of smooth muscle hypertrophy. http://purl.obolibrary.org/obo/GO_2000478 positive regulation of metanephric podocyte development http://purl.obolibrary.org/obo/GO_0010720 positive regulation of cell development Any process that activates or increases the frequency, rate or extent of metanephric glomerular visceral epithelial cell development. http://purl.obolibrary.org/obo/GO_1905148 negative regulation of smooth muscle hypertrophy http://purl.obolibrary.org/obo/GO_0014745 negative regulation of muscle adaptation Any process that stops, prevents or reduces the frequency, rate or extent of smooth muscle hypertrophy. http://purl.obolibrary.org/obo/GO_2000489 regulation of hepatic stellate cell activation http://purl.obolibrary.org/obo/GO_0050865 regulation of cell activation Any process that modulates the frequency, rate or extent of hepatic stellate cell activation. http://purl.obolibrary.org/obo/GO_1905149 positive regulation of smooth muscle hypertrophy http://purl.obolibrary.org/obo/GO_0014744 positive regulation of muscle adaptation Any process that activates or increases the frequency, rate or extent of smooth muscle hypertrophy. http://purl.obolibrary.org/obo/GO_2000490 negative regulation of hepatic stellate cell activation http://purl.obolibrary.org/obo/GO_2000489 regulation of hepatic stellate cell activation Any process that stops, prevents or reduces the frequency, rate or extent of hepatic stellate cell activation. http://purl.obolibrary.org/obo/GO_1905150 regulation of voltage-gated sodium channel activity http://purl.obolibrary.org/obo/GO_2000649 regulation of sodium ion transmembrane transporter activity Any process that modulates the frequency, rate or extent of voltage-gated sodium channel activity. http://purl.obolibrary.org/obo/GO_2000491 positive regulation of hepatic stellate cell activation http://purl.obolibrary.org/obo/GO_2000489 regulation of hepatic stellate cell activation Any process that activates or increases the frequency, rate or extent of hepatic stellate cell activation. http://purl.obolibrary.org/obo/GO_1905152 positive regulation of voltage-gated sodium channel activity http://purl.obolibrary.org/obo/GO_2001259 positive regulation of cation channel activity Any process that activates or increases the frequency, rate or extent of voltage-gated sodium channel activity. http://purl.obolibrary.org/obo/GO_2000495 regulation of cell proliferation involved in compound eye morphogenesis http://purl.obolibrary.org/obo/GO_0042127 regulation of cell population proliferation Any process that modulates the frequency, rate or extent of cell proliferation involved in compound eye morphogenesis. http://purl.obolibrary.org/obo/GO_1905157 positive regulation of photosynthesis http://purl.obolibrary.org/obo/GO_0010109 regulation of photosynthesis Any process that activates or increases the frequency, rate or extent of photosynthesis. http://purl.obolibrary.org/obo/GO_1905165 regulation of lysosomal protein catabolic process http://purl.obolibrary.org/obo/GO_1904350 regulation of protein catabolic process in the vacuole Any process that modulates the frequency, rate or extent of lysosomal protein catabolic process. http://purl.obolibrary.org/obo/GO_2000497 positive regulation of cell proliferation involved in compound eye morphogenesis http://purl.obolibrary.org/obo/GO_2000495 regulation of cell proliferation involved in compound eye morphogenesis Any process that activates or increases the frequency, rate or extent of cell proliferation involved in compound eye morphogenesis. http://purl.obolibrary.org/obo/GO_1905166 negative regulation of lysosomal protein catabolic process http://purl.obolibrary.org/obo/GO_1905165 regulation of lysosomal protein catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of lysosomal protein catabolic process. http://purl.obolibrary.org/obo/GO_2000501 regulation of natural killer cell chemotaxis http://purl.obolibrary.org/obo/GO_1901623 regulation of lymphocyte chemotaxis Any process that modulates the frequency, rate or extent of natural killer cell chemotaxis. http://purl.obolibrary.org/obo/GO_1905167 positive regulation of lysosomal protein catabolic process http://purl.obolibrary.org/obo/GO_1905165 regulation of lysosomal protein catabolic process Any process that activates or increases the frequency, rate or extent of lysosomal protein catabolic process. http://purl.obolibrary.org/obo/GO_2000502 negative regulation of natural killer cell chemotaxis http://purl.obolibrary.org/obo/GO_2000501 regulation of natural killer cell chemotaxis Any process that stops, prevents or reduces the frequency, rate or extent of natural killer cell chemotaxis. http://purl.obolibrary.org/obo/GO_1905192 regulation of chloroplast fission http://purl.obolibrary.org/obo/GO_0033043 regulation of organelle organization Any process that modulates the frequency, rate or extent of chloroplast fission. http://purl.obolibrary.org/obo/GO_2000503 positive regulation of natural killer cell chemotaxis http://purl.obolibrary.org/obo/GO_0140131 positive regulation of lymphocyte chemotaxis Any process that activates or increases the frequency, rate or extent of natural killer cell chemotaxis. http://purl.obolibrary.org/obo/GO_1905193 negative regulation of chloroplast fission http://purl.obolibrary.org/obo/GO_0010639 negative regulation of organelle organization Any process that stops, prevents or reduces the frequency, rate or extent of chloroplast fission. http://purl.obolibrary.org/obo/GO_2000508 regulation of dendritic cell chemotaxis http://purl.obolibrary.org/obo/GO_0071675 regulation of mononuclear cell migration Any process that modulates the frequency, rate or extent of dendritic cell chemotaxis. http://purl.obolibrary.org/obo/GO_1905194 positive regulation of chloroplast fission http://purl.obolibrary.org/obo/GO_0010638 positive regulation of organelle organization Any process that activates or increases the frequency, rate or extent of chloroplast fission. http://purl.obolibrary.org/obo/GO_2000509 negative regulation of dendritic cell chemotaxis http://purl.obolibrary.org/obo/GO_0071676 negative regulation of mononuclear cell migration Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell chemotaxis. http://purl.obolibrary.org/obo/GO_1905213 negative regulation of mitotic chromosome condensation http://purl.obolibrary.org/obo/GO_0010948 negative regulation of cell cycle process Any process that stops, prevents or reduces the frequency, rate or extent of mitotic chromosome condensation. http://purl.obolibrary.org/obo/GO_2000510 positive regulation of dendritic cell chemotaxis http://purl.obolibrary.org/obo/GO_0071677 positive regulation of mononuclear cell migration Any process that activates or increases the frequency, rate or extent of dendritic cell chemotaxis. http://purl.obolibrary.org/obo/GO_1905219 regulation of platelet formation http://purl.obolibrary.org/obo/GO_0022604 regulation of cell morphogenesis Any process that modulates the frequency, rate or extent of platelet formation. http://purl.obolibrary.org/obo/GO_2000517 regulation of T-helper 1 cell activation http://purl.obolibrary.org/obo/GO_2000514 regulation of CD4-positive, alpha-beta T cell activation Any process that modulates the frequency, rate or extent of T-helper 1 cell activation. http://purl.obolibrary.org/obo/GO_1905220 negative regulation of platelet formation http://purl.obolibrary.org/obo/GO_0045638 negative regulation of myeloid cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of platelet formation. http://purl.obolibrary.org/obo/GO_2000518 negative regulation of T-helper 1 cell activation http://purl.obolibrary.org/obo/GO_2000517 regulation of T-helper 1 cell activation Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 1 cell activation. http://purl.obolibrary.org/obo/GO_1905221 positive regulation of platelet formation http://purl.obolibrary.org/obo/GO_0010770 positive regulation of cell morphogenesis Any process that activates or increases the frequency, rate or extent of platelet formation. http://purl.obolibrary.org/obo/GO_2000519 positive regulation of T-helper 1 cell activation http://purl.obolibrary.org/obo/GO_2000517 regulation of T-helper 1 cell activation Any process that activates or increases the frequency, rate or extent of T-helper 1 cell activation. http://purl.obolibrary.org/obo/GO_1905223 epicardium morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The developmental process by which an epicardium is generated and organized. http://purl.obolibrary.org/obo/GO_2000527 regulation of myeloid dendritic cell chemotaxis http://purl.obolibrary.org/obo/GO_2000508 regulation of dendritic cell chemotaxis Any process that modulates the frequency, rate or extent of myeloid dendritic cell chemotaxis. http://purl.obolibrary.org/obo/GO_1905232 cellular response to L-glutamate http://purl.obolibrary.org/obo/GO_1902065 response to L-glutamate Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-glutamate(1-) stimulus. http://purl.obolibrary.org/obo/GO_2000528 negative regulation of myeloid dendritic cell chemotaxis http://purl.obolibrary.org/obo/GO_2000527 regulation of myeloid dendritic cell chemotaxis Any process that stops, prevents or reduces the frequency, rate or extent of myeloid dendritic cell chemotaxis. http://purl.obolibrary.org/obo/GO_1905275 Rohon-Beard neuron differentiation http://purl.obolibrary.org/obo/GO_0021953 central nervous system neuron differentiation The process in which a relatively unspecialized cell acquires the specialized features of a Rohon-Beard neuron. http://purl.obolibrary.org/obo/GO_2000529 positive regulation of myeloid dendritic cell chemotaxis http://purl.obolibrary.org/obo/GO_2000527 regulation of myeloid dendritic cell chemotaxis Any process that activates or increases the frequency, rate or extent of myeloid dendritic cell chemotaxis. http://purl.obolibrary.org/obo/GO_1905277 negative regulation of epithelial tube formation http://purl.obolibrary.org/obo/GO_1905276 regulation of epithelial tube formation Any process that stops, prevents or reduces the frequency, rate or extent of epithelial tube formation. http://purl.obolibrary.org/obo/GO_2000537 regulation of B cell chemotaxis http://purl.obolibrary.org/obo/GO_1901623 regulation of lymphocyte chemotaxis Any process that modulates the frequency, rate or extent of B cell chemotaxis. http://purl.obolibrary.org/obo/GO_1905285 fibrous ring of heart morphogenesis http://purl.obolibrary.org/obo/GO_0048729 tissue morphogenesis The developmental process by which a fibrous ring of heart is generated and organized. http://purl.obolibrary.org/obo/GO_2000538 positive regulation of B cell chemotaxis http://purl.obolibrary.org/obo/GO_0140131 positive regulation of lymphocyte chemotaxis Any process that activates or increases the frequency, rate or extent of B cell chemotaxis. http://purl.obolibrary.org/obo/GO_1905288 vascular associated smooth muscle cell apoptotic process http://purl.obolibrary.org/obo/GO_0034390 smooth muscle cell apoptotic process Any apoptotic process in a vascular associated smooth muscle cell. http://purl.obolibrary.org/obo/GO_2000547 regulation of dendritic cell dendrite assembly http://purl.obolibrary.org/obo/GO_0120032 regulation of plasma membrane bounded cell projection assembly Any process that modulates the frequency, rate or extent of dendritic cell dendrite assembly. http://purl.obolibrary.org/obo/GO_1905298 regulation of intestinal epithelial cell development http://purl.obolibrary.org/obo/GO_0060284 regulation of cell development Any process that modulates the frequency, rate or extent of intestinal epithelial cell development. http://purl.obolibrary.org/obo/GO_2000548 negative regulation of dendritic cell dendrite assembly http://purl.obolibrary.org/obo/GO_0120033 negative regulation of plasma membrane bounded cell projection assembly Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell dendrite assembly. http://purl.obolibrary.org/obo/GO_1905299 negative regulation of intestinal epithelial cell development http://purl.obolibrary.org/obo/GO_0010721 negative regulation of cell development Any process that stops, prevents or reduces the frequency, rate or extent of intestinal epithelial cell development. http://purl.obolibrary.org/obo/GO_2000549 positive regulation of dendritic cell dendrite assembly http://purl.obolibrary.org/obo/GO_0120034 positive regulation of plasma membrane bounded cell projection assembly Any process that activates or increases the frequency, rate or extent of dendritic cell dendrite assembly. http://purl.obolibrary.org/obo/GO_2000550 negative regulation of B cell chemotaxis http://purl.obolibrary.org/obo/GO_2000537 regulation of B cell chemotaxis Any process that stops, prevents or reduces the frequency, rate or extent of B cell chemotaxis. http://purl.obolibrary.org/obo/GO_1905300 positive regulation of intestinal epithelial cell development http://purl.obolibrary.org/obo/GO_0010720 positive regulation of cell development Any process that activates or increases the frequency, rate or extent of intestinal epithelial cell development. http://purl.obolibrary.org/obo/GO_1905304 regulation of cardiac myofibril assembly http://purl.obolibrary.org/obo/GO_1902115 regulation of organelle assembly Any process that modulates the frequency, rate or extent of cardiac myofibril assembly. http://purl.obolibrary.org/obo/GO_1905305 negative regulation of cardiac myofibril assembly http://purl.obolibrary.org/obo/GO_2000726 negative regulation of cardiac muscle cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of cardiac myofibril assembly. http://purl.obolibrary.org/obo/GO_1905306 positive regulation of cardiac myofibril assembly http://purl.obolibrary.org/obo/GO_1902117 positive regulation of organelle assembly Any process that activates or increases the frequency, rate or extent of cardiac myofibril assembly. http://purl.obolibrary.org/obo/GO_1905310 regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis http://purl.obolibrary.org/obo/GO_0030334 regulation of cell migration Any process that modulates the frequency, rate or extent of cardiac neural crest cell migration involved in outflow tract morphogenesis. http://purl.obolibrary.org/obo/GO_1905312 positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis http://purl.obolibrary.org/obo/GO_0030335 positive regulation of cell migration Any process that activates or increases the frequency, rate or extent of cardiac neural crest cell migration involved in outflow tract morphogenesis. http://purl.obolibrary.org/obo/GO_1905315 cell proliferation involved in endocardial cushion morphogenesis http://purl.obolibrary.org/obo/GO_0061323 cell proliferation involved in heart morphogenesis Any cell proliferation that is involved in endocardial cushion morphogenesis. http://purl.obolibrary.org/obo/GO_1905319 mesenchymal stem cell migration http://purl.obolibrary.org/obo/GO_0016477 cell migration The orderly movement of a mesenchymal stem cell from one site to another. http://purl.obolibrary.org/obo/GO_1905320 regulation of mesenchymal stem cell migration http://purl.obolibrary.org/obo/GO_0030334 regulation of cell migration Any process that modulates the frequency, rate or extent of mesenchymal stem cell migration. http://purl.obolibrary.org/obo/GO_1905321 negative regulation of mesenchymal stem cell migration http://purl.obolibrary.org/obo/GO_0030336 negative regulation of cell migration Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal stem cell migration. http://purl.obolibrary.org/obo/GO_1905322 positive regulation of mesenchymal stem cell migration http://purl.obolibrary.org/obo/GO_0030335 positive regulation of cell migration Any process that activates or increases the frequency, rate or extent of mesenchymal stem cell migration. http://purl.obolibrary.org/obo/GO_1905351 pericyte cell migration http://purl.obolibrary.org/obo/GO_0016477 cell migration The orderly movement of a pericyte cell from one site to another. http://purl.obolibrary.org/obo/GO_1905384 regulation of protein localization to presynapse http://purl.obolibrary.org/obo/GO_1902473 regulation of protein localization to synapse Any process that modulates the frequency, rate or extent of protein localization to presynapse. http://purl.obolibrary.org/obo/GO_2000551 regulation of T-helper 2 cell cytokine production http://purl.obolibrary.org/obo/GO_0002828 regulation of type 2 immune response Any process that modulates the frequency, rate or extent of T-helper 2 cell cytokine production. http://purl.obolibrary.org/obo/GO_1905385 negative regulation of protein localization to presynapse http://purl.obolibrary.org/obo/GO_1903828 negative regulation of protein localization Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to presynapse. http://purl.obolibrary.org/obo/GO_2000552 negative regulation of T-helper 2 cell cytokine production http://purl.obolibrary.org/obo/GO_2000551 regulation of T-helper 2 cell cytokine production Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 2 cell cytokine production. http://purl.obolibrary.org/obo/GO_1905386 positive regulation of protein localization to presynapse http://purl.obolibrary.org/obo/GO_1902474 positive regulation of protein localization to synapse Any process that activates or increases the frequency, rate or extent of protein localization to presynapse. http://purl.obolibrary.org/obo/GO_2000553 positive regulation of T-helper 2 cell cytokine production http://purl.obolibrary.org/obo/GO_2000551 regulation of T-helper 2 cell cytokine production Any process that activates or increases the frequency, rate or extent of T-helper 2 cell cytokine production. http://purl.obolibrary.org/obo/GO_1905397 activated CD8-positive, alpha-beta T cell apoptotic process http://purl.obolibrary.org/obo/GO_0070231 T cell apoptotic process Any apoptotic process in an activated CD8-positive, alpha-beta T cell. http://purl.obolibrary.org/obo/GO_2000554 regulation of T-helper 1 cell cytokine production http://purl.obolibrary.org/obo/GO_0002825 regulation of T-helper 1 type immune response Any process that modulates the frequency, rate or extent of T-helper 1 cell cytokine production. http://purl.obolibrary.org/obo/GO_1905398 activated CD4-positive, alpha-beta T cell apoptotic process http://purl.obolibrary.org/obo/GO_0070231 T cell apoptotic process Any apoptotic process in an activated CD4-positive, alpha-beta T cell. http://purl.obolibrary.org/obo/GO_2000555 negative regulation of T-helper 1 cell cytokine production http://purl.obolibrary.org/obo/GO_2000554 regulation of T-helper 1 cell cytokine production Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 1 cell cytokine production. http://purl.obolibrary.org/obo/GO_1905399 regulation of activated CD4-positive, alpha-beta T cell apoptotic process http://purl.obolibrary.org/obo/GO_0070232 regulation of T cell apoptotic process Any process that modulates the frequency, rate or extent of activated CD4-positive, alpha-beta T cell apoptotic process. http://purl.obolibrary.org/obo/GO_2000556 positive regulation of T-helper 1 cell cytokine production http://purl.obolibrary.org/obo/GO_2000554 regulation of T-helper 1 cell cytokine production Any process that activates or increases the frequency, rate or extent of T-helper 1 cell cytokine production. http://purl.obolibrary.org/obo/GO_1905400 negative regulation of activated CD4-positive, alpha-beta T cell apoptotic process http://purl.obolibrary.org/obo/GO_0070233 negative regulation of T cell apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of activated CD4-positive, alpha-beta T cell apoptotic process. http://purl.obolibrary.org/obo/GO_2000561 regulation of CD4-positive, alpha-beta T cell proliferation http://purl.obolibrary.org/obo/GO_2000514 regulation of CD4-positive, alpha-beta T cell activation Any process that modulates the frequency, rate or extent of CD4-positive, alpha-beta T cell proliferation. http://purl.obolibrary.org/obo/GO_1905401 positive regulation of activated CD4-positive, alpha-beta T cell apoptotic process http://purl.obolibrary.org/obo/GO_0070234 positive regulation of T cell apoptotic process Any process that activates or increases the frequency, rate or extent of activated CD4-positive, alpha-beta T cell apoptotic process. http://purl.obolibrary.org/obo/GO_2000562 negative regulation of CD4-positive, alpha-beta T cell proliferation http://purl.obolibrary.org/obo/GO_2000561 regulation of CD4-positive, alpha-beta T cell proliferation Any process that stops, prevents or reduces the frequency, rate or extent of CD4-positive, alpha-beta T cell proliferation. http://purl.obolibrary.org/obo/GO_1905402 regulation of activated CD8-positive, alpha-beta T cell apoptotic process http://purl.obolibrary.org/obo/GO_0070232 regulation of T cell apoptotic process Any process that modulates the frequency, rate or extent of activated CD8-positive, alpha-beta T cell apoptotic process. http://purl.obolibrary.org/obo/GO_2000563 positive regulation of CD4-positive, alpha-beta T cell proliferation http://purl.obolibrary.org/obo/GO_2000561 regulation of CD4-positive, alpha-beta T cell proliferation Any process that activates or increases the frequency, rate or extent of CD4-positive, alpha-beta T cell proliferation. http://purl.obolibrary.org/obo/GO_1905403 negative regulation of activated CD8-positive, alpha-beta T cell apoptotic process http://purl.obolibrary.org/obo/GO_0070233 negative regulation of T cell apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of activated CD8-positive, alpha-beta T cell apoptotic process. http://purl.obolibrary.org/obo/GO_2000564 regulation of CD8-positive, alpha-beta T cell proliferation http://purl.obolibrary.org/obo/GO_2001185 regulation of CD8-positive, alpha-beta T cell activation Any process that modulates the frequency, rate or extent of CD8-positive, alpha-beta T cell proliferation. http://purl.obolibrary.org/obo/GO_1905404 positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process http://purl.obolibrary.org/obo/GO_0070234 positive regulation of T cell apoptotic process Any process that activates or increases the frequency, rate or extent of activated CD8-positive, alpha-beta T cell apoptotic process. http://purl.obolibrary.org/obo/GO_2000565 negative regulation of CD8-positive, alpha-beta T cell proliferation http://purl.obolibrary.org/obo/GO_2000564 regulation of CD8-positive, alpha-beta T cell proliferation Any process that stops, prevents or reduces the frequency, rate or extent of CD8-positive, alpha-beta T cell proliferation. http://purl.obolibrary.org/obo/GO_1905413 regulation of dense core granule exocytosis http://purl.obolibrary.org/obo/GO_0017158 regulation of calcium ion-dependent exocytosis Any process that modulates the frequency, rate or extent of dense core granule exocytosis. http://purl.obolibrary.org/obo/GO_2000566 positive regulation of CD8-positive, alpha-beta T cell proliferation http://purl.obolibrary.org/obo/GO_2000564 regulation of CD8-positive, alpha-beta T cell proliferation Any process that activates or increases the frequency, rate or extent of CD8-positive, alpha-beta T cell proliferation. http://purl.obolibrary.org/obo/GO_1905414 negative regulation of dense core granule exocytosis http://purl.obolibrary.org/obo/GO_1905413 regulation of dense core granule exocytosis Any process that stops, prevents or reduces the frequency, rate or extent of dense core granule exocytosis. http://purl.obolibrary.org/obo/GO_2000567 regulation of memory T cell activation http://purl.obolibrary.org/obo/GO_0050863 regulation of T cell activation Any process that modulates the frequency, rate or extent of memory T cell activation. http://purl.obolibrary.org/obo/GO_1905415 positive regulation of dense core granule exocytosis http://purl.obolibrary.org/obo/GO_1905413 regulation of dense core granule exocytosis Any process that activates or increases the frequency, rate or extent of dense core granule exocytosis. http://purl.obolibrary.org/obo/GO_2000568 positive regulation of memory T cell activation http://purl.obolibrary.org/obo/GO_2000567 regulation of memory T cell activation Any process that activates or increases the frequency, rate or extent of memory T cell activation. http://purl.obolibrary.org/obo/GO_1905429 response to glycine http://purl.obolibrary.org/obo/GO_1901698 response to nitrogen compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycine stimulus. http://purl.obolibrary.org/obo/GO_2000569 regulation of T-helper 2 cell activation http://purl.obolibrary.org/obo/GO_2000514 regulation of CD4-positive, alpha-beta T cell activation Any process that modulates the frequency, rate or extent of T-helper 2 cell activation. http://purl.obolibrary.org/obo/GO_1905430 cellular response to glycine http://purl.obolibrary.org/obo/GO_1901701 cellular response to oxygen-containing compound Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycine stimulus. http://purl.obolibrary.org/obo/GO_2000570 positive regulation of T-helper 2 cell activation http://purl.obolibrary.org/obo/GO_2000569 regulation of T-helper 2 cell activation Any process that activates or increases the frequency, rate or extent of T-helper 2 cell activation. http://purl.obolibrary.org/obo/GO_1905432 regulation of retrograde trans-synaptic signaling by neuropeptide http://purl.obolibrary.org/obo/GO_0099177 regulation of trans-synaptic signaling Any process that modulates the frequency, rate or extent of retrograde trans-synaptic signaling by neuropeptide. http://purl.obolibrary.org/obo/GO_2000595 regulation of optic nerve formation http://purl.obolibrary.org/obo/GO_0022603 regulation of anatomical structure morphogenesis Any process that modulates the frequency, rate or extent of optic nerve formation. http://purl.obolibrary.org/obo/GO_1905433 negative regulation of retrograde trans-synaptic signaling by neuropeptide http://purl.obolibrary.org/obo/GO_0010648 negative regulation of cell communication Any process that stops, prevents or reduces the frequency, rate or extent of retrograde trans-synaptic signaling by neuropeptide. http://purl.obolibrary.org/obo/GO_2000596 negative regulation of optic nerve formation http://purl.obolibrary.org/obo/GO_2000595 regulation of optic nerve formation Any process that stops, prevents or reduces the frequency, rate or extent of optic nerve formation. http://purl.obolibrary.org/obo/GO_1905434 positive regulation of retrograde trans-synaptic signaling by neuropeptide http://purl.obolibrary.org/obo/GO_0010647 positive regulation of cell communication Any process that activates or increases the frequency, rate or extent of retrograde trans-synaptic signaling by neuropeptide. http://purl.obolibrary.org/obo/GO_2000597 positive regulation of optic nerve formation http://purl.obolibrary.org/obo/GO_2000595 regulation of optic nerve formation Any process that activates or increases the frequency, rate or extent of optic nerve formation. http://purl.obolibrary.org/obo/GO_2000609 regulation of thyroid hormone generation http://purl.obolibrary.org/obo/GO_0032350 regulation of hormone metabolic process Any process that modulates the frequency, rate or extent of thyroid hormone generation. http://purl.obolibrary.org/obo/GO_1905453 regulation of myeloid progenitor cell differentiation http://purl.obolibrary.org/obo/GO_1901532 regulation of hematopoietic progenitor cell differentiation Any process that modulates the frequency, rate or extent of myeloid progenitor cell differentiation. http://purl.obolibrary.org/obo/GO_2000610 negative regulation of thyroid hormone generation http://purl.obolibrary.org/obo/GO_2000609 regulation of thyroid hormone generation Any process that stops, prevents or reduces the frequency, rate or extent of thyroid hormone generation. http://purl.obolibrary.org/obo/GO_1905454 negative regulation of myeloid progenitor cell differentiation http://purl.obolibrary.org/obo/GO_1901533 negative regulation of hematopoietic progenitor cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of myeloid progenitor cell differentiation. http://purl.obolibrary.org/obo/GO_2000611 positive regulation of thyroid hormone generation http://purl.obolibrary.org/obo/GO_2000609 regulation of thyroid hormone generation Any process that activates or increases the frequency, rate or extent of thyroid hormone generation. http://purl.obolibrary.org/obo/GO_1905455 positive regulation of myeloid progenitor cell differentiation http://purl.obolibrary.org/obo/GO_1901534 positive regulation of hematopoietic progenitor cell differentiation Any process that activates or increases the frequency, rate or extent of myeloid progenitor cell differentiation. http://purl.obolibrary.org/obo/GO_2000612 regulation of thyroid-stimulating hormone secretion http://purl.obolibrary.org/obo/GO_0090276 regulation of peptide hormone secretion Any process that modulates the frequency, rate or extent of thyroid-stimulating hormone secretion. http://purl.obolibrary.org/obo/GO_1905456 regulation of lymphoid progenitor cell differentiation http://purl.obolibrary.org/obo/GO_1901532 regulation of hematopoietic progenitor cell differentiation Any process that modulates the frequency, rate or extent of lymphoid progenitor cell differentiation. http://purl.obolibrary.org/obo/GO_2000613 negative regulation of thyroid-stimulating hormone secretion http://purl.obolibrary.org/obo/GO_2000612 regulation of thyroid-stimulating hormone secretion Any process that stops, prevents or reduces the frequency, rate or extent of thyroid-stimulating hormone secretion. http://purl.obolibrary.org/obo/GO_1905457 negative regulation of lymphoid progenitor cell differentiation http://purl.obolibrary.org/obo/GO_1901533 negative regulation of hematopoietic progenitor cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of lymphoid progenitor cell differentiation. http://purl.obolibrary.org/obo/GO_2000614 positive regulation of thyroid-stimulating hormone secretion http://purl.obolibrary.org/obo/GO_2000612 regulation of thyroid-stimulating hormone secretion Any process that activates or increases the frequency, rate or extent of thyroid-stimulating hormone secretion. http://purl.obolibrary.org/obo/GO_1905458 positive regulation of lymphoid progenitor cell differentiation http://purl.obolibrary.org/obo/GO_1901534 positive regulation of hematopoietic progenitor cell differentiation Any process that activates or increases the frequency, rate or extent of lymphoid progenitor cell differentiation. http://purl.obolibrary.org/obo/GO_2000654 regulation of cellular response to testosterone stimulus http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of cellular response to testosterone stimulus. http://purl.obolibrary.org/obo/GO_1905459 regulation of vascular associated smooth muscle cell apoptotic process http://purl.obolibrary.org/obo/GO_0034391 regulation of smooth muscle cell apoptotic process Any process that modulates the frequency, rate or extent of vascular associated smooth muscle cell apoptotic process. http://purl.obolibrary.org/obo/GO_2000655 negative regulation of cellular response to testosterone stimulus http://purl.obolibrary.org/obo/GO_2000654 regulation of cellular response to testosterone stimulus Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to testosterone stimulus. http://purl.obolibrary.org/obo/GO_1905460 negative regulation of vascular associated smooth muscle cell apoptotic process http://purl.obolibrary.org/obo/GO_0034392 negative regulation of smooth muscle cell apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of vascular associated smooth muscle cell apoptotic process. http://purl.obolibrary.org/obo/GO_2000668 regulation of dendritic cell apoptotic process http://purl.obolibrary.org/obo/GO_2000106 regulation of leukocyte apoptotic process Any process that modulates the frequency, rate or extent of dendritic cell apoptotic process. http://purl.obolibrary.org/obo/GO_1905461 positive regulation of vascular associated smooth muscle cell apoptotic process http://purl.obolibrary.org/obo/GO_0034393 positive regulation of smooth muscle cell apoptotic process Any process that activates or increases the frequency, rate or extent of vascular associated smooth muscle cell apoptotic process. http://purl.obolibrary.org/obo/GO_2000669 negative regulation of dendritic cell apoptotic process http://purl.obolibrary.org/obo/GO_2000668 regulation of dendritic cell apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell apoptotic process. http://purl.obolibrary.org/obo/GO_1905492 positive regulation of branching morphogenesis of a nerve http://purl.obolibrary.org/obo/GO_0051240 positive regulation of multicellular organismal process Any process that activates or increases the frequency, rate or extent of branching morphogenesis of a nerve. http://purl.obolibrary.org/obo/GO_2000670 positive regulation of dendritic cell apoptotic process http://purl.obolibrary.org/obo/GO_2000668 regulation of dendritic cell apoptotic process Any process that activates or increases the frequency, rate or extent of dendritic cell apoptotic process. http://purl.obolibrary.org/obo/GO_1905503 regulation of motile cilium assembly http://purl.obolibrary.org/obo/GO_1902017 regulation of cilium assembly Any process that modulates the frequency, rate or extent of motile cilium assembly. http://purl.obolibrary.org/obo/GO_2000671 regulation of motor neuron apoptotic process http://purl.obolibrary.org/obo/GO_0043523 regulation of neuron apoptotic process Any process that modulates the frequency, rate or extent of motor neuron apoptotic process. http://purl.obolibrary.org/obo/GO_1905504 negative regulation of motile cilium assembly http://purl.obolibrary.org/obo/GO_1902018 negative regulation of cilium assembly Any process that stops, prevents or reduces the frequency, rate or extent of motile cilium assembly. http://purl.obolibrary.org/obo/GO_2000672 negative regulation of motor neuron apoptotic process http://purl.obolibrary.org/obo/GO_2000671 regulation of motor neuron apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of motor neuron apoptotic process. http://purl.obolibrary.org/obo/GO_1905505 positive regulation of motile cilium assembly http://purl.obolibrary.org/obo/GO_0045724 positive regulation of cilium assembly Any process that activates or increases the frequency, rate or extent of motile cilium assembly. http://purl.obolibrary.org/obo/GO_2000673 positive regulation of motor neuron apoptotic process http://purl.obolibrary.org/obo/GO_2000671 regulation of motor neuron apoptotic process Any process that activates or increases the frequency, rate or extent of motor neuron apoptotic process. http://purl.obolibrary.org/obo/GO_1905553 regulation of blood vessel branching http://purl.obolibrary.org/obo/GO_0060688 regulation of morphogenesis of a branching structure Any process that modulates the frequency, rate or extent of blood vessel branching. http://purl.obolibrary.org/obo/GO_2000674 regulation of type B pancreatic cell apoptotic process http://purl.obolibrary.org/obo/GO_1904035 regulation of epithelial cell apoptotic process Any process that modulates the frequency, rate or extent of type B pancreatic cell apoptotic process. http://purl.obolibrary.org/obo/GO_1905554 negative regulation of blood vessel branching http://purl.obolibrary.org/obo/GO_0016525 negative regulation of angiogenesis Any process that stops, prevents or reduces the frequency, rate or extent of blood vessel branching. http://purl.obolibrary.org/obo/GO_2000675 negative regulation of type B pancreatic cell apoptotic process http://purl.obolibrary.org/obo/GO_2000674 regulation of type B pancreatic cell apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of type B pancreatic cell apoptotic process. http://purl.obolibrary.org/obo/GO_2000676 positive regulation of type B pancreatic cell apoptotic process http://purl.obolibrary.org/obo/GO_2000674 regulation of type B pancreatic cell apoptotic process Any process that activates or increases the frequency, rate or extent of type B pancreatic cell apoptotic process. http://purl.obolibrary.org/obo/GO_1905555 positive regulation of blood vessel branching http://purl.obolibrary.org/obo/GO_0045766 positive regulation of angiogenesis Any process that activates or increases the frequency, rate or extent of blood vessel branching. http://purl.obolibrary.org/obo/GO_2000690 regulation of cardiac muscle cell myoblast differentiation http://purl.obolibrary.org/obo/GO_0051890 regulation of cardioblast differentiation Any process that modulates the frequency, rate or extent of cardiac muscle cell myoblast differentiation. http://purl.obolibrary.org/obo/GO_1905557 regulation of mitotic nuclear envelope disassembly http://purl.obolibrary.org/obo/GO_0010549 regulation of membrane disassembly Any process that modulates the frequency, rate or extent of mitotic nuclear envelope disassembly. http://purl.obolibrary.org/obo/GO_2000691 negative regulation of cardiac muscle cell myoblast differentiation http://purl.obolibrary.org/obo/GO_0051892 negative regulation of cardioblast differentiation Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle cell myoblast differentiation. http://purl.obolibrary.org/obo/GO_1905558 negative regulation of mitotic nuclear envelope disassembly http://purl.obolibrary.org/obo/GO_0051129 negative regulation of cellular component organization Any process that stops, prevents or reduces the frequency, rate or extent of mitotic nuclear envelope disassembly. http://purl.obolibrary.org/obo/GO_2000700 positive regulation of cardiac muscle cell myoblast differentiation http://purl.obolibrary.org/obo/GO_2000690 regulation of cardiac muscle cell myoblast differentiation Any process that activates or increases the frequency, rate or extent of cardiac muscle cell myoblast differentiation. http://purl.obolibrary.org/obo/GO_1905559 positive regulation of mitotic nuclear envelope disassembly http://purl.obolibrary.org/obo/GO_0090068 positive regulation of cell cycle process Any process that activates or increases the frequency, rate or extent of mitotic nuclear envelope disassembly. http://purl.obolibrary.org/obo/GO_2000729 positive regulation of mesenchymal cell proliferation involved in ureter development http://purl.obolibrary.org/obo/GO_0051094 positive regulation of developmental process Any process that activates or increases the frequency, rate or extent of mesenchymal cell proliferation involved in ureter development. http://purl.obolibrary.org/obo/GO_1905562 regulation of vascular endothelial cell proliferation http://purl.obolibrary.org/obo/GO_0001936 regulation of endothelial cell proliferation Any process that modulates the frequency, rate or extent of vascular endothelial cell proliferation. http://purl.obolibrary.org/obo/GO_2000739 regulation of mesenchymal stem cell differentiation http://purl.obolibrary.org/obo/GO_2000736 regulation of stem cell differentiation Any process that modulates the frequency, rate or extent of mesenchymal stem cell differentiation. http://purl.obolibrary.org/obo/GO_1905563 negative regulation of vascular endothelial cell proliferation http://purl.obolibrary.org/obo/GO_0001937 negative regulation of endothelial cell proliferation Any process that stops, prevents or reduces the frequency, rate or extent of vascular endothelial cell proliferation. http://purl.obolibrary.org/obo/GO_2000740 negative regulation of mesenchymal stem cell differentiation http://purl.obolibrary.org/obo/GO_2000739 regulation of mesenchymal stem cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal stem cell differentiation. http://purl.obolibrary.org/obo/GO_1905564 positive regulation of vascular endothelial cell proliferation http://purl.obolibrary.org/obo/GO_0001938 positive regulation of endothelial cell proliferation Any process that activates or increases the frequency, rate or extent of vascular endothelial cell proliferation. http://purl.obolibrary.org/obo/GO_2000741 positive regulation of mesenchymal stem cell differentiation http://purl.obolibrary.org/obo/GO_2000739 regulation of mesenchymal stem cell differentiation Any process that activates or increases the frequency, rate or extent of mesenchymal stem cell differentiation. http://purl.obolibrary.org/obo/GO_1905584 outer hair cell apoptotic process http://purl.obolibrary.org/obo/GO_0051402 neuron apoptotic process Any apoptotic process in an outer hair cell. http://purl.obolibrary.org/obo/GO_2000768 positive regulation of nephron tubule epithelial cell differentiation http://purl.obolibrary.org/obo/GO_0072182 regulation of nephron tubule epithelial cell differentiation Any process that activates or increases the frequency, rate or extent of nephron tubule epithelial cell differentiation. http://purl.obolibrary.org/obo/GO_1905585 regulation of outer hair cell apoptotic process http://purl.obolibrary.org/obo/GO_0043523 regulation of neuron apoptotic process Any process that modulates the frequency, rate or extent of outer hair cell apoptotic process. http://purl.obolibrary.org/obo/GO_2000791 negative regulation of mesenchymal cell proliferation involved in lung development http://purl.obolibrary.org/obo/GO_0072201 negative regulation of mesenchymal cell proliferation Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal cell proliferation involved in lung development. http://purl.obolibrary.org/obo/GO_1905586 negative regulation of outer hair cell apoptotic process http://purl.obolibrary.org/obo/GO_0043524 negative regulation of neuron apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of outer hair cell apoptotic process. http://purl.obolibrary.org/obo/GO_2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis http://purl.obolibrary.org/obo/GO_2000794 regulation of epithelial cell proliferation involved in lung morphogenesis Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell proliferation involved in lung morphogenesis. http://purl.obolibrary.org/obo/GO_1905587 positive regulation of outer hair cell apoptotic process http://purl.obolibrary.org/obo/GO_0043525 positive regulation of neuron apoptotic process Any process that activates or increases the frequency, rate or extent of outer hair cell apoptotic process. http://purl.obolibrary.org/obo/GO_2000797 regulation of amniotic stem cell differentiation http://purl.obolibrary.org/obo/GO_2000739 regulation of mesenchymal stem cell differentiation Any process that modulates the frequency, rate or extent of amniotic stem cell differentiation. http://purl.obolibrary.org/obo/GO_1905606 regulation of presynapse assembly http://purl.obolibrary.org/obo/GO_0051963 regulation of synapse assembly Any process that modulates the frequency, rate or extent of presynapse assembly. http://purl.obolibrary.org/obo/GO_1905607 negative regulation of presynapse assembly http://purl.obolibrary.org/obo/GO_1905606 regulation of presynapse assembly Any process that stops, prevents or reduces the frequency, rate or extent of presynapse assembly. http://purl.obolibrary.org/obo/GO_2000798 negative regulation of amniotic stem cell differentiation http://purl.obolibrary.org/obo/GO_2000797 regulation of amniotic stem cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of amniotic stem cell differentiation. http://purl.obolibrary.org/obo/GO_1905608 positive regulation of presynapse assembly http://purl.obolibrary.org/obo/GO_0051130 positive regulation of cellular component organization Any process that activates or increases the frequency, rate or extent of presynapse assembly. http://purl.obolibrary.org/obo/GO_2000799 positive regulation of amniotic stem cell differentiation http://purl.obolibrary.org/obo/GO_2000797 regulation of amniotic stem cell differentiation Any process that activates or increases the frequency, rate or extent of amniotic stem cell differentiation. http://purl.obolibrary.org/obo/GO_1905627 regulation of serotonin biosynthetic process http://purl.obolibrary.org/obo/GO_0009889 regulation of biosynthetic process Any process that modulates the frequency, rate or extent of serotonin biosynthetic process. http://purl.obolibrary.org/obo/GO_2000818 negative regulation of myoblast proliferation http://purl.obolibrary.org/obo/GO_0008285 negative regulation of cell population proliferation Any process that stops, prevents or reduces the frequency, rate or extent of myoblast proliferation. http://purl.obolibrary.org/obo/GO_1905628 negative regulation of serotonin biosynthetic process http://purl.obolibrary.org/obo/GO_0009890 negative regulation of biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of serotonin biosynthetic process. http://purl.obolibrary.org/obo/GO_2000828 regulation of parathyroid hormone secretion http://purl.obolibrary.org/obo/GO_0046883 regulation of hormone secretion Any process that modulates the frequency, rate or extent of parathyroid hormone secretion. http://purl.obolibrary.org/obo/GO_1905629 positive regulation of serotonin biosynthetic process http://purl.obolibrary.org/obo/GO_0009891 positive regulation of biosynthetic process Any process that activates or increases the frequency, rate or extent of serotonin biosynthetic process. http://purl.obolibrary.org/obo/GO_2000829 negative regulation of parathyroid hormone secretion http://purl.obolibrary.org/obo/GO_2000828 regulation of parathyroid hormone secretion Any process that stops, prevents or reduces the frequency, rate or extent of parathyroid hormone secretion. http://purl.obolibrary.org/obo/GO_1905651 regulation of artery morphogenesis http://purl.obolibrary.org/obo/GO_0022603 regulation of anatomical structure morphogenesis Any process that modulates the frequency, rate or extent of artery morphogenesis. http://purl.obolibrary.org/obo/GO_2000830 positive regulation of parathyroid hormone secretion http://purl.obolibrary.org/obo/GO_2000828 regulation of parathyroid hormone secretion Any process that activates or increases the frequency, rate or extent of parathyroid hormone secretion. http://purl.obolibrary.org/obo/GO_1905652 negative regulation of artery morphogenesis http://purl.obolibrary.org/obo/GO_2000181 negative regulation of blood vessel morphogenesis Any process that stops, prevents or reduces the frequency, rate or extent of artery morphogenesis. http://purl.obolibrary.org/obo/GO_2000834 regulation of androgen secretion http://purl.obolibrary.org/obo/GO_2000831 regulation of steroid hormone secretion Any process that modulates the frequency, rate or extent of androgen secretion. http://purl.obolibrary.org/obo/GO_1905653 positive regulation of artery morphogenesis http://purl.obolibrary.org/obo/GO_0051094 positive regulation of developmental process Any process that activates or increases the frequency, rate or extent of artery morphogenesis. http://purl.obolibrary.org/obo/GO_2000835 negative regulation of androgen secretion http://purl.obolibrary.org/obo/GO_2000834 regulation of androgen secretion Any process that stops, prevents or reduces the frequency, rate or extent of androgen secretion. http://purl.obolibrary.org/obo/GO_1990188 euchromatin binding http://purl.obolibrary.org/obo/GO_0003682 chromatin binding Binding to euchromatin, a dispersed and relatively uncompacted form of chromatin. http://purl.obolibrary.org/obo/GO_2000836 positive regulation of androgen secretion http://purl.obolibrary.org/obo/GO_2000834 regulation of androgen secretion Any process that activates or increases the frequency, rate or extent of androgen secretion. http://purl.obolibrary.org/obo/GO_1990654 sebum secreting cell proliferation http://purl.obolibrary.org/obo/GO_0050673 epithelial cell proliferation The multiplication or reproduction of sebocytes by cell division, resulting in the expansion of their population. A sebocyte is an epithelial cell that makes up the sebaceous glands, and secrete sebum. http://purl.obolibrary.org/obo/GO_2000843 regulation of testosterone secretion http://purl.obolibrary.org/obo/GO_0046883 regulation of hormone secretion Any process that modulates the frequency, rate or extent of testosterone secretion. http://purl.obolibrary.org/obo/GO_1990705 cholangiocyte proliferation http://purl.obolibrary.org/obo/GO_0050673 epithelial cell proliferation The multiplication or reproduction of cholangiocytes, resulting in the expansion of the cholangiocyte population. A cholangiocyte is an epithelial cell that is part of the bile duct. Cholangiocytes contribute to bile secretion via net release of bicarbonate and water. http://purl.obolibrary.org/obo/GO_2000844 negative regulation of testosterone secretion http://purl.obolibrary.org/obo/GO_2000843 regulation of testosterone secretion Any process that stops, prevents or reduces the frequency, rate or extent of testosterone secretion. http://purl.obolibrary.org/obo/GO_1990739 granulosa cell proliferation http://purl.obolibrary.org/obo/GO_0050673 epithelial cell proliferation The multiplication or reproduction of granulosa cells, resulting in the expansion of the granulosa cells population. A granulosa cell is a supporting cell for the developing female gamete in the ovary of mammals. They develop from the coelomic epithelial cells of the gonadal ridge. http://purl.obolibrary.org/obo/GO_2000845 positive regulation of testosterone secretion http://purl.obolibrary.org/obo/GO_2000843 regulation of testosterone secretion Any process that activates or increases the frequency, rate or extent of testosterone secretion. http://purl.obolibrary.org/obo/GO_1990751 Schwann cell chemotaxis http://purl.obolibrary.org/obo/GO_0036135 Schwann cell migration The directed movement of a Schwann cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis). http://purl.obolibrary.org/obo/GO_2000846 regulation of corticosteroid hormone secretion http://purl.obolibrary.org/obo/GO_2000831 regulation of steroid hormone secretion Any process that modulates the frequency, rate or extent of corticosteroid hormone secretion. http://purl.obolibrary.org/obo/GO_1990765 colon smooth muscle contraction http://purl.obolibrary.org/obo/GO_0006939 smooth muscle contraction A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry of the large intestine, exclusive of the rectum. The colon is that part of the large intestine that connects the small intestine to the rectum. http://purl.obolibrary.org/obo/GO_2000847 negative regulation of corticosteroid hormone secretion http://purl.obolibrary.org/obo/GO_2000846 regulation of corticosteroid hormone secretion Any process that stops, prevents or reduces the frequency, rate or extent of corticosteroid hormone secretion. http://purl.obolibrary.org/obo/GO_1990768 gastric mucosal blood circulation http://purl.obolibrary.org/obo/GO_0008015 blood circulation The flow of blood through the gastric mucosa of an animal, enabling the transport of nutrients and the removal of waste products. http://purl.obolibrary.org/obo/GO_2000848 positive regulation of corticosteroid hormone secretion http://purl.obolibrary.org/obo/GO_2000846 regulation of corticosteroid hormone secretion Any process that activates or increases the frequency, rate or extent of corticosteroid hormone secretion. http://purl.obolibrary.org/obo/GO_1990770 small intestine smooth muscle contraction http://purl.obolibrary.org/obo/GO_0006939 smooth muscle contraction A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry in the intestine between the stomach and the large intestine. http://purl.obolibrary.org/obo/GO_2000855 regulation of mineralocorticoid secretion http://purl.obolibrary.org/obo/GO_2000846 regulation of corticosteroid hormone secretion Any process that modulates the frequency, rate or extent of mineralocorticoid secretion. http://purl.obolibrary.org/obo/GO_1990791 dorsal root ganglion development http://purl.obolibrary.org/obo/GO_0061548 ganglion development The process whose specific outcome is the progression of a dorsal root ganglion over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_2000856 negative regulation of mineralocorticoid secretion http://purl.obolibrary.org/obo/GO_2000855 regulation of mineralocorticoid secretion Any process that stops, prevents or reduces the frequency, rate or extent of mineralocorticoid secretion. http://purl.obolibrary.org/obo/GO_1990863 acinar cell proliferation http://purl.obolibrary.org/obo/GO_0050673 epithelial cell proliferation The multiplication or reproduction of acinar cells, resulting in the expansion of a cell population. An acinar cell is a secretory cell that is grouped together with other cells of the same type to form grape-shaped clusters known as acini (singular acinus). http://purl.obolibrary.org/obo/GO_2000857 positive regulation of mineralocorticoid secretion http://purl.obolibrary.org/obo/GO_2000855 regulation of mineralocorticoid secretion Any process that activates or increases the frequency, rate or extent of mineralocorticoid secretion. http://purl.obolibrary.org/obo/GO_1990874 vascular associated smooth muscle cell proliferation http://purl.obolibrary.org/obo/GO_0048659 smooth muscle cell proliferation The multiplication or reproduction of vascular smooth muscle cells, resulting in the expansion of a cell population. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels. http://purl.obolibrary.org/obo/GO_2000859 negative regulation of aldosterone secretion http://purl.obolibrary.org/obo/GO_2000856 negative regulation of mineralocorticoid secretion Any process that stops, prevents or reduces the frequency, rate or extent of aldosterone secretion. http://purl.obolibrary.org/obo/GO_1990922 hepatic stellate cell proliferation http://purl.obolibrary.org/obo/GO_0048144 fibroblast proliferation The multiplication or reproduction of hepatic stellate cells, resulting in the expansion of a hepatic stellate cell population. Hepatic stellate cells are found in the perisinusoidal space of the liver, and are capable of multiple roles including storage of retinol, presentation of antigen to T cells (including CD1d-restricted NKT cells), and upon activation, production of extracellular matrix components. This cell type comprises approximately 8-15% of total cells in the liver. http://purl.obolibrary.org/obo/GO_2000860 positive regulation of aldosterone secretion http://purl.obolibrary.org/obo/GO_2000857 positive regulation of mineralocorticoid secretion Any process that activates or increases the frequency, rate or extent of aldosterone secretion. http://purl.obolibrary.org/obo/GO_2000864 regulation of estradiol secretion http://purl.obolibrary.org/obo/GO_2000831 regulation of steroid hormone secretion Any process that modulates the frequency, rate or extent of estradiol secretion. http://purl.obolibrary.org/obo/GO_2000865 negative regulation of estradiol secretion http://purl.obolibrary.org/obo/GO_2000864 regulation of estradiol secretion Any process that stops, prevents or reduces the frequency, rate or extent of estradiol secretion. http://purl.obolibrary.org/obo/GO_2000018 regulation of male gonad development http://purl.obolibrary.org/obo/GO_1905939 regulation of gonad development Any process that modulates the frequency, rate or extent of male gonad development. http://purl.obolibrary.org/obo/GO_2000866 positive regulation of estradiol secretion http://purl.obolibrary.org/obo/GO_2000864 regulation of estradiol secretion Any process that activates or increases the frequency, rate or extent of estradiol secretion. http://purl.obolibrary.org/obo/GO_2000019 negative regulation of male gonad development http://purl.obolibrary.org/obo/GO_1905940 negative regulation of gonad development Any process that stops, prevents, or reduces the frequency, rate or extent of male gonad development. http://purl.obolibrary.org/obo/GO_2000870 regulation of progesterone secretion http://purl.obolibrary.org/obo/GO_2000194 regulation of female gonad development Any process that modulates the frequency, rate or extent of progesterone secretion. http://purl.obolibrary.org/obo/GO_2000871 negative regulation of progesterone secretion http://purl.obolibrary.org/obo/GO_2000870 regulation of progesterone secretion Any process that stops, prevents or reduces the frequency, rate or extent of progesterone secretion. http://purl.obolibrary.org/obo/GO_2000020 positive regulation of male gonad development http://purl.obolibrary.org/obo/GO_1905941 positive regulation of gonad development Any process that activates or increases the frequency, rate or extent of male gonad development. http://purl.obolibrary.org/obo/GO_2000035 regulation of stem cell division http://purl.obolibrary.org/obo/GO_0051302 regulation of cell division Any process that modulates the frequency, rate or extent of stem cell division. http://purl.obolibrary.org/obo/GO_2000872 positive regulation of progesterone secretion http://purl.obolibrary.org/obo/GO_2000870 regulation of progesterone secretion Any process that activates or increases the frequency, rate or extent of progesterone secretion. http://purl.obolibrary.org/obo/GO_2000172 regulation of branching morphogenesis of a nerve http://purl.obolibrary.org/obo/GO_0060688 regulation of morphogenesis of a branching structure Any process that modulates the frequency, rate or extent of branching morphogenesis of a nerve. http://purl.obolibrary.org/obo/GO_2000882 negative regulation of starch catabolic process http://purl.obolibrary.org/obo/GO_0045912 negative regulation of carbohydrate metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of starch catabolic process. http://purl.obolibrary.org/obo/GO_2000973 regulation of pro-B cell differentiation http://purl.obolibrary.org/obo/GO_1905456 regulation of lymphoid progenitor cell differentiation Any process that modulates the frequency, rate or extent of pro-B cell differentiation. http://purl.obolibrary.org/obo/GO_2000504 positive regulation of blood vessel remodeling http://purl.obolibrary.org/obo/GO_0060312 regulation of blood vessel remodeling Any process that activates or increases the frequency, rate or extent of blood vessel remodeling. http://purl.obolibrary.org/obo/GO_2000974 negative regulation of pro-B cell differentiation http://purl.obolibrary.org/obo/GO_2000973 regulation of pro-B cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of pro-B cell differentiation. http://purl.obolibrary.org/obo/GO_2001222 regulation of neuron migration http://purl.obolibrary.org/obo/GO_0030334 regulation of cell migration Any process that modulates the frequency, rate or extent of neuron migration. http://purl.obolibrary.org/obo/GO_2000975 positive regulation of pro-B cell differentiation http://purl.obolibrary.org/obo/GO_2000973 regulation of pro-B cell differentiation Any process that activates or increases the frequency, rate or extent of pro-B cell differentiation. http://purl.obolibrary.org/obo/GO_2001223 negative regulation of neuron migration http://purl.obolibrary.org/obo/GO_0030336 negative regulation of cell migration Any process that stops, prevents or reduces the frequency, rate or extent of neuron migration. http://purl.obolibrary.org/obo/GO_2001224 positive regulation of neuron migration http://purl.obolibrary.org/obo/GO_0030335 positive regulation of cell migration Any process that activates or increases the frequency, rate or extent of neuron migration. http://purl.obolibrary.org/obo/GO_2000977 regulation of forebrain neuron differentiation http://purl.obolibrary.org/obo/GO_0045664 regulation of neuron differentiation Any process that modulates the frequency, rate or extent of forebrain neuron differentiation. http://purl.obolibrary.org/obo/GO_2000978 negative regulation of forebrain neuron differentiation http://purl.obolibrary.org/obo/GO_0045665 negative regulation of neuron differentiation Any process that stops, prevents or reduces the frequency, rate or extent of forebrain neuron differentiation. http://purl.obolibrary.org/obo/UBERON_0000003 naris http://purl.obolibrary.org/obo/UBERON_0000161 orifice Orifice of the olfactory system. The naris is the route by which odorants enter the olfactory system[MAH]. http://purl.obolibrary.org/obo/UBERON_0000006 islet of Langerhans http://purl.obolibrary.org/obo/UBERON_0034922 cell cluster The clusters of hormone-producing cells that are scattered throughout the pancreas. http://purl.obolibrary.org/obo/GO_2000979 positive regulation of forebrain neuron differentiation http://purl.obolibrary.org/obo/GO_0045666 positive regulation of neuron differentiation Any process that activates or increases the frequency, rate or extent of forebrain neuron differentiation. http://purl.obolibrary.org/obo/UBERON_0000009 submucosa http://purl.obolibrary.org/obo/UBERON_0004923 organ component layer A layer of dense irregular connective tissue that lines organs and supports the mucosa, as well as joins the mucosa to the bulk of underlying smooth muscle. [WP,unvetted]. http://purl.obolibrary.org/obo/GO_2001026 regulation of endothelial cell chemotaxis http://purl.obolibrary.org/obo/GO_0010594 regulation of endothelial cell migration Any process that modulates the frequency, rate or extent of endothelial cell chemotaxis. http://purl.obolibrary.org/obo/GO_2001027 negative regulation of endothelial cell chemotaxis http://purl.obolibrary.org/obo/GO_0010596 negative regulation of endothelial cell migration Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell chemotaxis. http://purl.obolibrary.org/obo/UBERON_0000011 parasympathetic nervous system http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision The parasympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system. Parasympathetic nerves emerge cranially as pre ganglionic fibers from oculomotor, facial, glossopharyngeal and vagus and from the sacral region of the spinal cord. Most neurons are cholinergic and responses are mediated by muscarinic receptors. The parasympathetic system innervates, for example: salivary glands, thoracic and abdominal viscera, bladder and genitalia[GO]. http://purl.obolibrary.org/obo/GO_2001035 regulation of tongue muscle cell differentiation http://purl.obolibrary.org/obo/GO_1902809 regulation of skeletal muscle fiber differentiation Any process that modulates the frequency, rate or extent of tongue muscle cell differentiation. http://purl.obolibrary.org/obo/GO_2001036 negative regulation of tongue muscle cell differentiation http://purl.obolibrary.org/obo/GO_2001035 regulation of tongue muscle cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of tongue muscle cell differentiation. http://purl.obolibrary.org/obo/UBERON_0000012 somatic nervous system http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision Part of peripheral nervous system that includes the somatic parts of the cranial and spinal nerves and their ganglia and the peripheral sensory receptors. http://purl.obolibrary.org/obo/GO_2001037 positive regulation of tongue muscle cell differentiation http://purl.obolibrary.org/obo/GO_2001035 regulation of tongue muscle cell differentiation Any process that activates or increases the frequency, rate or extent of tongue muscle cell differentiation. http://purl.obolibrary.org/obo/UBERON_0000013 sympathetic nervous system http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision The sympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system (the other being the parasympathetic nervous system). The sympathetic preganglionic neurons have their cell bodies in the thoracic and lumbar regions of the spinal cord and connect to the paravertebral chain of sympathetic ganglia. Innervate heart and blood vessels, sweat glands, viscera and the adrenal medulla. Most sympathetic neurons, but not all, use noradrenaline as a post-ganglionic neurotransmitter [GO]. http://purl.obolibrary.org/obo/GO_2001049 regulation of tendon cell differentiation http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the frequency, rate or extent of tendon cell differentiation. http://purl.obolibrary.org/obo/GO_2001050 negative regulation of tendon cell differentiation http://purl.obolibrary.org/obo/GO_2001049 regulation of tendon cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of tendon cell differentiation. http://purl.obolibrary.org/obo/UBERON_0000015 non-material anatomical boundary http://purl.obolibrary.org/obo/UBERON_0000466 immaterial anatomical entity A non-material anatomical entity of two dimensions. Anatomical boundaries are contiguous structures. http://purl.obolibrary.org/obo/GO_2001051 positive regulation of tendon cell differentiation http://purl.obolibrary.org/obo/GO_0045597 positive regulation of cell differentiation Any process that activates or increases the frequency, rate or extent of tendon cell differentiation. http://purl.obolibrary.org/obo/UBERON_0000018 compound eye http://purl.obolibrary.org/obo/UBERON_0015165 multi-unit eye A light sensing organ composed of ommatidia. http://purl.obolibrary.org/obo/GO_2001069 glycogen binding http://purl.obolibrary.org/obo/GO_0030247 polysaccharide binding Binding to glycogen. http://purl.obolibrary.org/obo/UBERON_0000019 camera-type eye http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure An organ of sight that includes the camera-type eyeball and supporting structures such as the lacrimal apparatus, the conjunctiva, the eyelid. http://purl.obolibrary.org/obo/GO_2001070 starch binding http://purl.obolibrary.org/obo/GO_0030247 polysaccharide binding Binding to starch. http://purl.obolibrary.org/obo/GO_2001151 regulation of renal water transport http://purl.obolibrary.org/obo/GO_0051049 regulation of transport Any process that modulates the frequency, rate or extent of renal water transport. http://purl.obolibrary.org/obo/UBERON_0000025 tube http://purl.obolibrary.org/obo/UBERON_0004111 anatomical conduit Any hollow cylindrical anatomical structure containing a lumen through which substances are transported. http://purl.obolibrary.org/obo/GO_2001152 negative regulation of renal water transport http://purl.obolibrary.org/obo/GO_0051051 negative regulation of transport Any process that stops, prevents or reduces the frequency, rate or extent of renal water transport. http://purl.obolibrary.org/obo/UBERON_0000026 appendage http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision Major subdivision of an organism that protrudes from the body[DOS, CARO]. http://purl.obolibrary.org/obo/UBERON_0000030 lamina propria http://purl.obolibrary.org/obo/UBERON_0004923 organ component layer A thin layer of loose connective tissue which lies beneath the epithelium and together with the epithelium constitutes the mucosa[WP]. The lamina propria contains capillaries and a central lacteal (lymph vessel) in the small intestine, as well as lymphoid tissue. Lamina propria also contains glands with the ducts opening on to the mucosal epithelium, that secrete mucus and serous secretions. http://purl.obolibrary.org/obo/GO_2001153 positive regulation of renal water transport http://purl.obolibrary.org/obo/GO_0051050 positive regulation of transport Any process that activates or increases the frequency, rate or extent of renal water transport. http://purl.obolibrary.org/obo/GO_2001169 regulation of ATP biosynthetic process http://purl.obolibrary.org/obo/GO_1900371 regulation of purine nucleotide biosynthetic process Any process that modulates the frequency, rate or extent of ATP biosynthetic process. http://purl.obolibrary.org/obo/UBERON_0000031 lamina propria of trachea http://purl.obolibrary.org/obo/UBERON_0004779 respiratory system lamina propria A lamina propria that is part of a respiratory airway. http://purl.obolibrary.org/obo/GO_2001170 negative regulation of ATP biosynthetic process http://purl.obolibrary.org/obo/GO_2001169 regulation of ATP biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of ATP biosynthetic process. http://purl.obolibrary.org/obo/UBERON_0000035 primary ovarian follicle http://purl.obolibrary.org/obo/UBERON_0001305 ovarian follicle An ovarian follicle that has one layer of granulosa cells. http://purl.obolibrary.org/obo/GO_2001171 positive regulation of ATP biosynthetic process http://purl.obolibrary.org/obo/GO_2001169 regulation of ATP biosynthetic process Any process that activates or increases the frequency, rate or extent of ATP biosynthetic process. http://purl.obolibrary.org/obo/UBERON_0000036 secondary ovarian follicle http://purl.obolibrary.org/obo/UBERON_0001305 ovarian follicle A maturing ovarian follicle that has two more more layers of granulosa cells, up to the onset of antrum formation. http://purl.obolibrary.org/obo/GO_2001198 regulation of dendritic cell differentiation http://purl.obolibrary.org/obo/GO_1902105 regulation of leukocyte differentiation Any process that modulates the frequency, rate or extent of dendritic cell differentiation. http://purl.obolibrary.org/obo/UBERON_0000037 tertiary ovarian follicle http://purl.obolibrary.org/obo/UBERON_0001305 ovarian follicle A follicle that has reached the most mature stage of folliculogenesis, characterized by the presence of the antrum. http://purl.obolibrary.org/obo/GO_2001199 negative regulation of dendritic cell differentiation http://purl.obolibrary.org/obo/GO_2001198 regulation of dendritic cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell differentiation. http://purl.obolibrary.org/obo/UBERON_0000038 follicular fluid http://purl.obolibrary.org/obo/UBERON_0000463 organism substance The fluid surrounding the ovum and granulosa cells in the ovarian follicle. http://purl.obolibrary.org/obo/GO_2001200 positive regulation of dendritic cell differentiation http://purl.obolibrary.org/obo/GO_2001198 regulation of dendritic cell differentiation Any process that activates or increases the frequency, rate or extent of dendritic cell differentiation. http://purl.obolibrary.org/obo/UBERON_0000039 follicular antrum http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space Region of ovarian follicle filled with follicular fluid. http://purl.obolibrary.org/obo/GO_2001204 regulation of osteoclast development http://purl.obolibrary.org/obo/GO_1903706 regulation of hemopoiesis Any process that modulates the frequency, rate or extent of osteoclast development. http://purl.obolibrary.org/obo/UBERON_0000042 serous membrane http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure Multi-tissue structure that is comprised of a secretory epithelial layer (mesothelium) and a connective tissue layer. http://purl.obolibrary.org/obo/UBERON_0000043 tendon http://purl.obolibrary.org/obo/UBERON_0007846 dense regular connective tissue Dense regular connective tissue that connects muscle to bone[VSAO]. http://purl.obolibrary.org/obo/GO_2001205 negative regulation of osteoclast development http://purl.obolibrary.org/obo/GO_2001204 regulation of osteoclast development Any process that stops, prevents or reduces the frequency, rate or extent of osteoclast development. http://purl.obolibrary.org/obo/UBERON_0000044 dorsal root ganglion http://purl.obolibrary.org/obo/UBERON_0001800 sensory ganglion Sensory ganglia located on the dorsal spinal roots within the vertebral column. The spinal ganglion cells are pseudounipolar. The single primary branch bifurcates sending a peripheral process to carry sensory information from the periphery and a central branch which relays that information to the spinal cord or brain. (MSH) * ganglion found on the posterior root of each spinal nerve, composed of the unipolar nerve cell bodies of the sensory neurons of the nerve. (CSP). http://purl.obolibrary.org/obo/UBERON_0000045 ganglion http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure A biological tissue mass, most commonly a mass of nerve cell bodies. http://purl.obolibrary.org/obo/GO_2001206 positive regulation of osteoclast development http://purl.obolibrary.org/obo/GO_2001204 regulation of osteoclast development Any process that activates or increases the frequency, rate or extent of osteoclast development. http://purl.obolibrary.org/obo/UBERON_0000047 simple eye http://purl.obolibrary.org/obo/UBERON_0000970 eye An eye with one concave chamber. Note that 'simple' does not imply a reduced level of complexity or acuity. http://purl.obolibrary.org/obo/GO_2001212 regulation of vasculogenesis http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the frequency, rate or extent of vasculogenesis. http://purl.obolibrary.org/obo/UBERON_0000052 fornix of brain http://purl.obolibrary.org/obo/UBERON_0007702 tract of brain A C-shaped bundle of fibres (axons) in the brain, and carries signals from the hippocampus to the mammillary bodies and septal nuclei. It is typically divided into the columns (crus), body, commissure and the pre-commissural and post-commissural fornix (MM). http://purl.obolibrary.org/obo/GO_2001213 negative regulation of vasculogenesis http://purl.obolibrary.org/obo/GO_2001212 regulation of vasculogenesis Any process that stops, prevents or reduces the frequency, rate or extent of vasculogenesis. http://purl.obolibrary.org/obo/UBERON_0000053 macula lutea http://purl.obolibrary.org/obo/UBERON_0000064 organ part An oval area in the retina, usually located temporal to the posterior pole of the eye and slightly below the level of the optic disk. It is characterized by the presence of a yellow pigment diffusely permeating the inner layers, contains the fovea centralis in its center, and provides the best phototopic visual acuity. It is devoid of retinal blood vessels, except in its periphery, and receives nourishment from the choriocapillaris of the choroid. (From Cline et al., Dictionary of Visual Science, 4th ed). http://purl.obolibrary.org/obo/GO_2001214 positive regulation of vasculogenesis http://purl.obolibrary.org/obo/GO_0045597 positive regulation of cell differentiation Any process that activates or increases the frequency, rate or extent of vasculogenesis. http://purl.obolibrary.org/obo/UBERON_0000054 macula http://purl.obolibrary.org/obo/UBERON_0000479 tissue Thickened areas of the saccule or utricle where the termination of the vestibular nerve occurs[MESH,modified]. http://purl.obolibrary.org/obo/PR_000000681 transient receptor potential cation channel TRPV http://purl.obolibrary.org/obo/PR_000044657 transient receptor potential channel protein A transient receptor potential channel protein that is a member of the subfamily V of the transient receptor potential cation channels (TRPs), with amino- and carboxyl-terminal intracellular domains separated by a domain (common with other ion channels) containing six transmembrane helices (S1-S6) in which the last two helices (S5 and S6) flank a loop, called the pore loop, which determines ion selectivity. The amino-terminal domain contains up to 6 copies of detectable ankyrin repeat (Pfam:PF00023). Most TRPs are relatively non-selective. They may be modulated by voltage changes but channel gating is generally effected by other means. http://purl.obolibrary.org/obo/UBERON_0000055 vessel http://purl.obolibrary.org/obo/UBERON_0004111 anatomical conduit A tubular structure that contains, conveys body fluid, such as blood or lymph. http://purl.obolibrary.org/obo/PR_000001002 CD19 molecule http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CD19 gene or a 1:1 ortholog thereof. It is composed of an N-terminal extracellular domain containing two Ig-like C2-type (immunoglobulin-like) domains, followed by a single-pass transmembrane segment and a cytoplasmic C-terminal tail. CD19 expression is restricted to members of the B cell lineage. It functions as a co-receptor for B-cell antigen receptor (BCR), regulating signal transduction. http://purl.obolibrary.org/obo/UBERON_0000058 duct http://purl.obolibrary.org/obo/UBERON_0000063 organ subunit A tubular structure that transports secreted or excreted substances. http://purl.obolibrary.org/obo/UBERON_0000060 anatomical wall http://purl.obolibrary.org/obo/UBERON_0000064 organ part Organ component adjacent to an organ cavity and which consists of a maximal aggregate of organ component layers. http://purl.obolibrary.org/obo/PR_000001003 CD34 molecule http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CD34 gene or a 1:1 ortholog thereof. It is a leukocyte membrane protein expressed specifically by lymphohematopoietic progenitor cells. It contains a single-pass transmembrane domain and that show distinct expression on early hematopoietic precursors and vascular-associated tissue. Acts as a scaffold that presents selectin carbohydrate ligands in a clustered, tissue specific manner to allow for higher avidity interactions between leukocytes and endothelial cells during the inflammatory process. In common with related sialomucins (endoglycan and podocalyxin), the extracellular region is dominated by an N-terminal mucin-like domain, which is densely substituted with sialylated O-linked carbohydrates. The mucin-like region is followed by a cysteine-containing and presumably globular domain. This domain may fold into an immunoglobulin-like structure as the positions of 2 of the cysteines are conserved in the C2 set of the immunoglobulin superfamily. The cytoplasmic domain is around 73-76 residues long and highly conserved. http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure http://purl.obolibrary.org/obo/UBERON_0000465 material anatomical entity Material anatomical entity that is a single connected structure with inherent 3D shape generated by coordinated expression of the organism's own genome. http://purl.obolibrary.org/obo/PR_000001005 integrin alpha with A domain http://purl.obolibrary.org/obo/PR_000025796 integrin alpha An integrin alpha that contains an A domain. A hallmark of this class is the presence of a von Willebrand factor type A domain (Pfam:PF00092) (I-domain) of approximately 200 amino acid residues at the N terminus, which confers divalent cation binding properties. Unlike other integrin alpha proteins, they do not undergo proteolytic cleavage. http://purl.obolibrary.org/obo/UBERON_0000062 organ http://purl.obolibrary.org/obo/UBERON_0010000 multicellular anatomical structure Anatomical structure that performs a specific function or group of functions [WP]. http://purl.obolibrary.org/obo/PR_000001006 receptor-type tyrosine-protein phosphatase C http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human PTPRC gene or a 1:1 ortholog thereof. It is composed of an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic protein-tyrosine phosphatase domains. Contains 1 to 3 copies of the Fibronectin type III domain (Pfam:PF00041) followed by two copies of the Protein-tyrosine phosphatase (Pfam:PF00102) domain. Receptor-type tyrosine-protein phosphatase C (CD45) regulates signal transduction and lymphocyte activation by specific association with receptor molecules on T and B cells. Multiple isoforms of CD45 (180-235 kDa) can be generated asa result of alternative splicing of three variable exons 4(A), 5(B) and 6(C), encoding sequences at the N-terminal extracellular domain of the molecule. http://purl.obolibrary.org/obo/UBERON_0000063 organ subunit http://purl.obolibrary.org/obo/UBERON_0000064 organ part A part of an organ that constitutes a distinct modular sub-unit. In some cases, the organ may also contain other sub-units of identical or similar types, in other cases this may be a distinct entity. http://purl.obolibrary.org/obo/PR_000001007 integrin alpha-1 http://purl.obolibrary.org/obo/PR_000001005 integrin alpha with A domain An integrin alpha with A domain that is a translation product of the human ITGA1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000064 organ part http://purl.obolibrary.org/obo/UBERON_0010000 multicellular anatomical structure A multicellular structure that is a part of an organ. http://purl.obolibrary.org/obo/PR_000001008 integrin alpha-2 http://purl.obolibrary.org/obo/PR_000001005 integrin alpha with A domain An integrin alpha with A domain that is a translation product of the human ITGA2 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000066 fully formed stage http://purl.obolibrary.org/obo/UBERON_0000105 life cycle stage The stage of development at which the animal is fully formed, including immaturity and maturity. Includes both sexually immature stage, and adult stage. http://purl.obolibrary.org/obo/PR_000001010 integrin alpha-E http://purl.obolibrary.org/obo/PR_000001005 integrin alpha with A domain An integrin alpha with A domain that is a translation product of the human ITGAE gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000068 embryo stage http://purl.obolibrary.org/obo/UBERON_0000105 life cycle stage A life cycle stage that starts with fertilization and ends with the fully formed embryo. http://purl.obolibrary.org/obo/PR_000001012 integrin alpha-M http://purl.obolibrary.org/obo/PR_000001005 integrin alpha with A domain An integrin alpha with A domain that is a translation product of the human ITGAM gene or a 1:1 ortholog thereof. They constitute subunits of the integrin alpha-M/beta-2 receptor. This receptor is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is also a receptor for fibrinogen, factor X and ICAM1. http://purl.obolibrary.org/obo/UBERON_0000069 larval stage http://purl.obolibrary.org/obo/UBERON_0000105 life cycle stage A distinct juvenile stage many animals undergo before metamorphosis into adults. Animals with indirect development such as insects, amphibians, or cnidarians typically have a larval phase of their life cycle. http://purl.obolibrary.org/obo/PR_000001013 integrin alpha-X http://purl.obolibrary.org/obo/PR_000001005 integrin alpha with A domain An integrin alpha with A domain that is a translation product of the human ITGAX gene or a 1:1 ortholog thereof. Integrin alpha-X complexed with beta-2 is a receptor for fibrinogen. It recognizes the sequence GPR in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis. http://purl.obolibrary.org/obo/UBERON_0000071 death stage http://purl.obolibrary.org/obo/UBERON_0000105 life cycle stage End of the life of an organism. http://purl.obolibrary.org/obo/PR_000001014 receptor-type tyrosine-protein phosphatase C isoform CD45RABC http://purl.obolibrary.org/obo/PR_000001006 receptor-type tyrosine-protein phosphatase C A receptor-type tyrosine-protein phosphatase C that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P08575-3 or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000072 proximo-distal subdivision of respiratory tract http://purl.obolibrary.org/obo/UBERON_0013522 subdivision of tube An section of a respiratory tract. http://purl.obolibrary.org/obo/PR_000001015 receptor-type tyrosine-protein phosphatase C isoform CD45RA http://purl.obolibrary.org/obo/PR_000050216 receptor-type tyrosine-protein phosphatase C isoform CD45R A receptor-type tyrosine-protein phosphatase C isoform CD45R that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P08575-8 or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000073 regional part of nervous system http://purl.obolibrary.org/obo/UBERON_0000481 multi-tissue structure Any part or collection of parts of the central or peripheral nervous system. Parts may span both CNS and PNS. http://purl.obolibrary.org/obo/PR_000001017 receptor-type tyrosine-protein phosphatase C isoform CD45RO http://purl.obolibrary.org/obo/PR_000001006 receptor-type tyrosine-protein phosphatase C A receptor-type tyrosine-protein phosphatase C that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P08575-4 or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000074 renal glomerulus http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure A capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the vertebrate kidney[GO]. http://purl.obolibrary.org/obo/PR_000001020 CD3 epsilon http://purl.obolibrary.org/obo/PR_000001018 CD3 subunit with immunoglobulin domain A CD3 subunit with immunoglobulin domain that is a translation product of the human CD3E gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000075 subdivision of skeletal system http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision Anatomical cluster consisting of the skeletal elements and articular elements that are part of an individual subdivision of the organism. http://purl.obolibrary.org/obo/PR_000001022 neural cell adhesion molecule http://purl.obolibrary.org/obo/PR_000000001 protein A protein with a domain composition consisting of a large extracellular domain, including five Ig-like C2-type domains followed by two copies of the Fibronectin type-III domain (Pfam:PF00041), a single-pass transmembrane domain and a short cytoplasmic C-terminal domain. http://purl.obolibrary.org/obo/PR_000001023 neural cell adhesion molecule NCAM http://purl.obolibrary.org/obo/PR_000001022 neural cell adhesion molecule A neural cell adhesion molecule that is involved in neuronal development, synaptic plasticity, and regeneration. http://purl.obolibrary.org/obo/UBERON_0000076 external ectoderm http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue The surface (external) layer of ectoderm which begins to proliferate shortly after separation from the neuroectoderm. http://purl.obolibrary.org/obo/PR_000001024 neural cell adhesion molecule 1 http://purl.obolibrary.org/obo/PR_000001023 neural cell adhesion molecule NCAM A neural cell adhesion molecule NCAM that is a translation product of the human NCAM1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000077 mixed endoderm/mesoderm-derived structure http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure An anatomical structure that develops from the endoderm and the mesoderm. http://purl.obolibrary.org/obo/PR_000001025 C-type lectin with multiple lectin domains http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a type I transmembrane receptor with an N-terminal cysteine-rich domain, a single Fibronectin type II (FNII) domain (Pfam:PF00040) and eight to ten copies of the Lectin C-type domain (Pfam:PF00059) (CTLDs). The presence of multiple copies of the CTLD domain is a hallmark of this class. http://purl.obolibrary.org/obo/UBERON_0000078 mixed ectoderm/mesoderm/endoderm-derived structure http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure An anatomical structure that develops from the ectoderm, mesoderm and endoderm. http://purl.obolibrary.org/obo/PR_000001026 lymphocyte antigen 75 http://purl.obolibrary.org/obo/PR_000001025 C-type lectin with multiple lectin domains A C-type lectin with multiple lectin domains that is a translation product of the mouse LY75 gene or a 1:1 ortholog thereof. It consists of 12 extracellular domains (an N-terminal cysteine-rich domain, a fibronectin type II domain and 10 C-type carbohydrate recognition domains), a transmembrane region and a small cytoplasmic C terminus containing a single Tyr residue, but no obvious kinase domain. http://purl.obolibrary.org/obo/UBERON_0000080 mesonephros http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure The second stage of the kidney. It serves as the main excretory organ of aquatic vertebrates and as a temporary embryonic kidney in higher vertebrates. It is composed of the mesonephric duct (also called the Wolffian duct), mesonephric tubules, and associated capillary tufts. A single tubule and its associated capillary tuft is called a mesonephric excretory unit; these units are similar in structure and function to nephrons of the adult kidney. The mesonephros is derived from intermediate mesoderm in the vertebrate embryo. http://purl.obolibrary.org/obo/PR_000001064 transient receptor potential cation channel TRPV2 http://purl.obolibrary.org/obo/PR_000000681 transient receptor potential cation channel TRPV A transient receptor potential cation channel TRPV that is a translation product of the human TRPV2 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000081 metanephros http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure In mammals, the metanephros is the excretory organ of the fetus, which develops into the mature kidney and is formed from the rear portion of the nephrogenic cord. The metanephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine[GO]. http://purl.obolibrary.org/obo/PR_000001065 transient receptor potential cation channel TRPV1 http://purl.obolibrary.org/obo/PR_000000681 transient receptor potential cation channel TRPV A transient receptor potential cation channel TRPV that is a translation product of the human TRPV1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000083 mesonephric tubule http://purl.obolibrary.org/obo/UBERON_0006555 excretory tube A mesonephric tubule is an epithelial tube that is part of the mesonephros[GO]. Genital ridge that is next to the mesonephros[WP]. http://purl.obolibrary.org/obo/PR_000001082 CD160 molecule http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CD160 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000084 ureteric bud http://purl.obolibrary.org/obo/UBERON_0034969 epithelial layer of duct An epithelial swelling on the Wolffian duct that elongates to invade the adjacent metanephric mesenchyme[MP]. http://purl.obolibrary.org/obo/PR_000001083 CD2 molecule http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CD2 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000085 morula http://purl.obolibrary.org/obo/UBERON_0000922 embryo A spherical embryonic mass of blastomeres formed before the blastula and resulting from cleavage of the fertilized ovum. http://purl.obolibrary.org/obo/PR_000001084 T-cell surface glycoprotein CD8 alpha chain http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CD8A gene or a 1:1 ortholog thereof. CD8 is a transmembrane that is a co-receptor for MHC class-I antigen/T-cell receptor interaction. The most common form of CD8 is composed of a CD8 alpha and a CD8 beta chain. http://purl.obolibrary.org/obo/UBERON_0000086 zona pellucida http://purl.obolibrary.org/obo/UBERON_0005764 acellular membrane A glycoprotein membrane surrounding the plasma membrane of an oocyte. It is a vital constitutive part of the latter, external but not extraneous to it. The zona pellucida first appears in multilaminar primary oocytes. http://purl.obolibrary.org/obo/PR_000001085 T-cell surface glycoprotein CD8 beta chain http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CD8B gene or a 1:1 ortholog thereof. CD8 is a transmembrane receptor that is a co-receptor for MHC class-I antigen/T-cell receptor interaction. The most common form of CD8 is composed of a CD8 alpha and a CD8 beta chain. http://purl.obolibrary.org/obo/UBERON_0000087 inner cell mass http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure A mass of cells that develop into the body of the embryo and some extraembryonic tissues. http://purl.obolibrary.org/obo/PR_000001087 adhesion G-protein coupled receptor http://purl.obolibrary.org/obo/PR_000030035 G-protein coupled receptor A G-protein coupled receptor with a 7 transmembrane (secretin family) domain (Pfam:PF00002) preceded by an amino-terminal region containing one or more functional domains with adhesion-like motifs. http://purl.obolibrary.org/obo/UBERON_0000088 trophoblast http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure The mesectodermal cell layer arising from the trophectoderm that erodes the uterine mucosa and contributes to the formation of the placenta. http://purl.obolibrary.org/obo/UBERON_0000091 bilaminar disc http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure A flattened, almost circular bilaminar plate of cells formed when the inner cell mass (aka embryoblast) forms two epithelial layers, each of a distinct lineage, separated by an extracellular basement membrane: the external (dorsal) layer is called the epiblast and the internal (ventral) layer is called the hypoblast (aka primitive endoderm); together, they compose the bilaminar embryonic disc. http://purl.obolibrary.org/obo/UBERON_0000092 post-embryonic stage http://purl.obolibrary.org/obo/UBERON_0000105 life cycle stage Stage succeeding embryo, including mature structure. http://purl.obolibrary.org/obo/UBERON_0000093 sulcus http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space A depression or fissure in the surface of an organ. http://purl.obolibrary.org/obo/UBERON_0000094 membrane organ http://purl.obolibrary.org/obo/UBERON_0000062 organ Nonparenchymatous organ that primarily consists of dense connective tissue organized into a sheet which interconnects two or more organs, separates two or more body spaces from one another, or surrounds an organ or body part. Examples: interosseous membrane of forearm, obturator membrane, tympanic membrane, fibrous pericardium, fascia lata, dura mater. [FMA]. http://purl.obolibrary.org/obo/UBERON_0000095 cardiac neural crest http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue Portion of neural crest that develops from the dorsal neural tube. It overlaps the vagal neural crest and migrates to populate the pharyngeal arches 3, 4 and 6 (producing structures in the head) and to the heart, forming connective tissue that separates the great vessels of the heart. [Wikipedia]. http://purl.obolibrary.org/obo/UBERON_0000101 lobe of lung http://purl.obolibrary.org/obo/UBERON_0009912 anatomical lobe A lung lobe is one of the rounded projections that compose the lung[GO]. http://purl.obolibrary.org/obo/UBERON_0000102 lung vasculature http://purl.obolibrary.org/obo/UBERON_0006876 vasculature of organ The lung vasculature is composed of the tubule structures that carry blood or lymph in the lungs[GO]. http://purl.obolibrary.org/obo/UBERON_0000104 life cycle http://purl.obolibrary.org/obo/UBERON_0000000 processual entity An entire span of an organism's life. In metazoans, commences with the zygote stage and ends with the death of the organism. http://purl.obolibrary.org/obo/UBERON_0000105 life cycle stage http://purl.obolibrary.org/obo/UBERON_0000000 processual entity A spatiotemporal region encompassing some part of the life cycle of an organism. http://purl.obolibrary.org/obo/UBERON_0000106 zygote stage http://purl.obolibrary.org/obo/UBERON_0000105 life cycle stage A stage at which the organism is a single cell produced by means of sexual reproduction. http://purl.obolibrary.org/obo/UBERON_0000107 cleavage stage http://purl.obolibrary.org/obo/UBERON_0000105 life cycle stage The first few specialized divisions of an activated animal egg; Stage consisting of division of cells in the early embryo. The zygotes of many species undergo rapid cell cycles with no significant growth, producing a cluster of cells the same size as the original zygote. The different cells derived from cleavage are called blastomeres and form a compact mass called the morula. Cleavage ends with the formation of the blastula. http://purl.obolibrary.org/obo/UBERON_0000108 blastula stage http://purl.obolibrary.org/obo/UBERON_0000105 life cycle stage An early stage of embryonic development in animals. It is produced by cleavage of a fertilized ovum and consists of a spherical layer of around 128 cells surrounding a central fluid-filled cavity called the blastocoel. The blastula follows the morula and precedes the gastrula in the developmental sequence. http://purl.obolibrary.org/obo/UBERON_0000109 gastrula stage http://purl.obolibrary.org/obo/UBERON_0000105 life cycle stage A stage defined by complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals. The details of gastrulation vary from species to species, but usually result in the formation of the three primary germ layers, ectoderm, mesoderm and endoderm. http://purl.obolibrary.org/obo/UBERON_0000110 neurula stage http://purl.obolibrary.org/obo/UBERON_0000105 life cycle stage A chordate developmental stage defined by the formation of a tube from the flat layer of ectodermal cells known as the neural plate. This will give rise to the central nervous system. http://purl.obolibrary.org/obo/UBERON_0000111 organogenesis stage http://purl.obolibrary.org/obo/UBERON_0000105 life cycle stage A stage at which the ectoderm, endoderm, and mesoderm develop into the internal organs of the organism. http://purl.obolibrary.org/obo/UBERON_0000113 post-juvenile adult stage http://purl.obolibrary.org/obo/UBERON_0000105 life cycle stage The stage of being a sexually mature adult animal. http://purl.obolibrary.org/obo/PR_000001094 rhodopsin-like G-protein coupled receptor http://purl.obolibrary.org/obo/PR_000030035 G-protein coupled receptor A G-protein coupled receptor that contains the 7 transmembrane receptor (rhodopsin family) domain (Pfam:PF00001), which includes 7 transmembrane helices (TMI-TM7) with 3 intracellular loops (IL1-IL3) and 3 extracellular loops (EL1-EL3) between the helices. The amino-terminal region is extracellular and the carboxyl-terminal region is intracellular. Rhodopsin-like G-protein coupled receptors (GPCRs) are unique among the several classes of GPCRs in that most have a very short amino-terminal segment and several characteristic sequence motifs, particularly NSxxNPxxY in TM7 and D/E-R-Y/F between TM3 and loop IL2. Most bind their ligands within a cavity between the TM regions. http://purl.obolibrary.org/obo/UBERON_0000114 lung connective tissue http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure The connective tissue located between the respiratory (airway and alveolar) epithelium, the capillary endothelium and pleural mesothelium; it contains basement membrane composed of collagen, elastin, proteoglycans, and fibronectin. http://purl.obolibrary.org/obo/PR_000001107 D(1)-like dopamine receptor http://purl.obolibrary.org/obo/PR_000044633 dopamine receptor A dopamine receptor that is a product of the DRD1 or DRD5 gene. The active form binds dopamine and its activity is mediated by G proteins that cause activation of adenylate cyclase. http://purl.obolibrary.org/obo/UBERON_0000115 lung epithelium http://purl.obolibrary.org/obo/UBERON_0004815 lower respiratory tract epithelium The epithelial layer of the lung. http://purl.obolibrary.org/obo/PR_000001108 D(2)-like dopamine receptor http://purl.obolibrary.org/obo/PR_000044633 dopamine receptor A dopamine receptor that is a product of the DRD2, DRD3, or DRD4 gene. The active form binds dopamine and its activity is mediated by G proteins that cause inhibition of adenylate cyclase. http://purl.obolibrary.org/obo/UBERON_0000117 respiratory tube http://purl.obolibrary.org/obo/UBERON_0000025 tube A tube in the respiratory system. Examples: bronchus, bronchiole, trachea. http://purl.obolibrary.org/obo/PR_000001119 animal opsin http://purl.obolibrary.org/obo/PR_000036194 eukaryotic protein A rhodopsin-like G-protein coupled receptor that is a translation product of the human OPN1LW, OPN1MW, OPN1SW, RHO, OPN3, OPN4, or OPN5 genes, 1:1 orthologs thereof, or a semi-ortholog thereof in Metazoa. The active form binds a vitamin A-based retinaldehyde chromophore through a Schiff base linkage to a Lys residue in the seventh transmembrane alpha helix. http://purl.obolibrary.org/obo/UBERON_0000118 lung bud http://purl.obolibrary.org/obo/UBERON_0005153 epithelial bud Structure derived from foregut that becomes a lung[GO]. http://purl.obolibrary.org/obo/PR_000001128 chemokine receptor http://purl.obolibrary.org/obo/PR_000001094 rhodopsin-like G-protein coupled receptor A rhodopsin-like G-protein coupled receptor that in active form binds to one or more chemokines. http://purl.obolibrary.org/obo/UBERON_0000119 cell layer http://purl.obolibrary.org/obo/UBERON_0000957 lamina Portion of tissue, that consists of single layer of cells connected to each other by cell junctions. Examples: layer of glial cells; epithelium. http://purl.obolibrary.org/obo/PR_000001175 D(1A) dopamine receptor http://purl.obolibrary.org/obo/PR_000001107 D(1)-like dopamine receptor A D(1)-like dopamine receptor that is a translation product of the human DRD1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001177 D(2) dopamine receptor http://purl.obolibrary.org/obo/PR_000001108 D(2)-like dopamine receptor A D(2)-like dopamine receptor that is a translation product of the human DRD2 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000120 blood brain barrier http://purl.obolibrary.org/obo/UBERON_0000119 cell layer Cell layer consisting of lining cells that separates the central nervous system and the bloodstream. The BBB may consist of endothelial cells or glial cells. An endothelial barrier may have arisen independently several times during evolution. In bichir and lungfish the barrier is formed by brain endothelial cells, while in sturgeon it is formed by a complex perivascular glial sheath, but with no detectable tight junctions. http://purl.obolibrary.org/obo/PR_000001197 chemokine receptor CCR1/3/1L http://purl.obolibrary.org/obo/PR_000001128 chemokine receptor A chemokine receptor that is a translation product of the human CCR1 or CCR3 genes, the mouse CCR1L1 gene, 1:1 orthologs thereof, or a semi-ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000121 perineurium http://purl.obolibrary.org/obo/UBERON_0011822 dense irregular connective tissue A layer of thin, concentrically arranged cells with interspersed collagen that lies within the epineurium. The perineurium is a component of the blood–nerve barrier and is essential for protecting axons and their associated Schwann cells from ionic flux, toxins and infection. http://purl.obolibrary.org/obo/PR_000001199 C-C chemokine receptor type 2 http://purl.obolibrary.org/obo/PR_000001128 chemokine receptor A chemokine receptor that is a translation product of the human CCR2 gene or a 1:1 ortholog thereof. The preferred ligands include CCL2, CCL7, CCL8, CCL13. http://purl.obolibrary.org/obo/UBERON_0000122 neuron projection bundle http://purl.obolibrary.org/obo/UBERON_0005162 multi cell part structure A fasciculated bundle of neuron projections (GO:0043005), largely or completely lacking synapses. http://purl.obolibrary.org/obo/PR_000001200 C-C chemokine receptor type 4 http://purl.obolibrary.org/obo/PR_000001128 chemokine receptor A chemokine receptor that is a translation product of the human CCR4 gene or a 1:1 ortholog thereof. The preferred ligands include CCL17 and CCL22. http://purl.obolibrary.org/obo/UBERON_0000124 epineurium http://purl.obolibrary.org/obo/UBERON_0011822 dense irregular connective tissue A loose connective tissue sheath surrounding each peripheral nerve. Composed mainly of colagen and fibroblasts, it forms a substantial covering over nerve trunks, then thins to an incomplete layer around smaller branches near their terminations. The epineurium is continuous centrally with the dura. Peripherally, it usually ends near the termination of a nerve fiber, but it may continue as the capsule of Meissner corpuscles and a few other encapsulated endings. Nolte, J. The Human Brain 3rd edition. http://purl.obolibrary.org/obo/PR_000001201 C-C chemokine receptor type 5 http://purl.obolibrary.org/obo/PR_000001128 chemokine receptor A chemokine receptor that is a translation product of the human CCR5 gene or a 1:1 ortholog thereof. The preferred ligands include CCL3, CCL4, CCL5, CCL8, CCL14. http://purl.obolibrary.org/obo/UBERON_0000125 neural nucleus http://purl.obolibrary.org/obo/UBERON_0011215 central nervous system cell part cluster A spatially aggregated collection of nerve cell bodies in the CNS, consisting of one or more subpopulations that share cell type, chemical phenotype, and connections, and including nearby cells that share the same cell type, chemical phenotype, and connections. (CUMBO). http://purl.obolibrary.org/obo/PR_000001202 C-C chemokine receptor type 6 http://purl.obolibrary.org/obo/PR_000001128 chemokine receptor A chemokine receptor that is a translation product of the human CCR6 gene or a 1:1 ortholog thereof. The preferred ligand is CCL20. http://purl.obolibrary.org/obo/UBERON_0000126 cranial nerve nucleus http://purl.obolibrary.org/obo/UBERON_0002308 nucleus of brain Nucleus that receives projections from or contains neurons that send projections through one of the cranial nerves. http://purl.obolibrary.org/obo/PR_000001203 C-C chemokine receptor type 7 http://purl.obolibrary.org/obo/PR_000001128 chemokine receptor A chemokine receptor that is a translation product of the human CCR7 gene or a 1:1 ortholog thereof. The preferred ligands are CCL19 and CCL21. http://purl.obolibrary.org/obo/UBERON_0000127 facial nucleus http://purl.obolibrary.org/obo/UBERON_0009662 hindbrain nucleus The group of motor neurons residing in the pons that innervate the muscles of facial expression. http://purl.obolibrary.org/obo/PR_000001206 CX3C chemokine receptor 1 http://purl.obolibrary.org/obo/PR_000001128 chemokine receptor A chemokine receptor that is a translation product of the human CX3CR1 gene or a 1:1 ortholog thereof. The preferred ligand is CX3CL1. http://purl.obolibrary.org/obo/UBERON_0000155 theca cell layer http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure A layer of the ovarian follicle that consists of theca cells. http://purl.obolibrary.org/obo/PR_000001207 C-X-C chemokine receptor type 3 http://purl.obolibrary.org/obo/PR_000001128 chemokine receptor A chemokine receptor that is a translation product of the human CXCR3 gene or a 1:1 ortholog thereof. The preferred ligands include CXCL9, CXCL10, CXCL11. http://purl.obolibrary.org/obo/UBERON_0000156 theca externa http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure The theca externa is the outer layers of the theca folliculi. It contains abundant collagen and is mainly supportive. http://purl.obolibrary.org/obo/PR_000001208 C-X-C chemokine receptor type 4 http://purl.obolibrary.org/obo/PR_000001128 chemokine receptor A chemokine receptor that is a translation product of the human CXCR4 gene or a 1:1 ortholog thereof. The preferred ligand is CXCL12. http://purl.obolibrary.org/obo/UBERON_0000157 theca interna http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure Theca interna cells express receptors for luteinizing hormone, which when activated will stimulate the production of androstenedione from cholesterol by the enzyme desmolase. Androstenedione ultimately gives the granulosa cells the precursor substrate for estrogen manufacturing. http://purl.obolibrary.org/obo/PR_000001209 C-X-C chemokine receptor type 5 http://purl.obolibrary.org/obo/PR_000001128 chemokine receptor A chemokine receptor that is a translation product of the human CXCR5 gene or a 1:1 ortholog thereof. The preferred ligand is CXCL13. http://purl.obolibrary.org/obo/UBERON_0000161 orifice http://purl.obolibrary.org/obo/UBERON_0004111 anatomical conduit Anatomical conduit that connects two adjacent body spaces (or a body space with the space surrounding the organism)[FMA,modified]. http://purl.obolibrary.org/obo/PR_000001224 medium-wave-sensitive opsin http://purl.obolibrary.org/obo/PR_000001119 animal opsin An animal opsin that is a translation product of the human OPN1MW, OPN1MW2, or OPN1MW3 genes, 1:1 orthologs thereof, or a semi-ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000162 cloaca http://purl.obolibrary.org/obo/UBERON_0013522 subdivision of tube Common chamber into which the intestines and excretory system opens. Arises during development in all vertebrates, but in many it becomes subdivided, lost or incorporated into other structures. http://purl.obolibrary.org/obo/PR_000001226 high affinity interleukin-8 receptor http://purl.obolibrary.org/obo/PR_000001128 chemokine receptor A chemokine receptor whose active form binds interleukin-8 with high affinity. http://purl.obolibrary.org/obo/UBERON_0000163 embryonic cloaca http://purl.obolibrary.org/obo/UBERON_0000162 cloaca Endoderm-lined chamber that develops as pouch-like dilation of the caudal end of the hindgut and receives the allantois ventrally and two mesonephric ducts laterally; caudally it ends blindly at the cloacal membrane formed by the union of proctodeal (anal pit) ectoderm and cloacal endoderm, with no intervening mesoderm[MP]. http://purl.obolibrary.org/obo/PR_000001243 melanopsin http://purl.obolibrary.org/obo/PR_000001119 animal opsin An animal opsin that is a translation product of the human OPN4 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000164 primitive urogenital sinus http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure The ventral part of the cloaca remaining after septation of the rectum, which further develops into part of the bladder, part of the prostatic part of the male urethra and the urethra and vestibule in females. http://purl.obolibrary.org/obo/PR_000001244 long-wave-sensitive opsin 1 http://purl.obolibrary.org/obo/PR_000001119 animal opsin An animal opsin that is a translation product of the human OPN1LW gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000166 oral opening http://purl.obolibrary.org/obo/UBERON_0000161 orifice The orifice that connects the mouth to the exterior of the body. http://purl.obolibrary.org/obo/PR_000001254 C-C chemokine receptor type 1 http://purl.obolibrary.org/obo/PR_000001197 chemokine receptor CCR1/3/1L A chemokine receptor CCR1/3/1L that is a translation product of the human CCR1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000168 proximal-distal subdivision of colon http://purl.obolibrary.org/obo/UBERON_0004921 subdivision of digestive tract A section dividing a colon along a proximal-distal axis. http://purl.obolibrary.org/obo/UBERON_0000170 pair of lungs http://purl.obolibrary.org/obo/UBERON_0034925 anatomical collection The pair of anatomical structures comprised of a left lung and right lung. http://purl.obolibrary.org/obo/PR_000001255 C-C chemokine receptor type 3 http://purl.obolibrary.org/obo/PR_000001197 chemokine receptor CCR1/3/1L A chemokine receptor CCR1/3/1L that is a translation product of the human CCR3 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000171 respiration organ http://purl.obolibrary.org/obo/UBERON_0000062 organ Organ that functions in gaseous exchange between an organism and its environment. In plants, microorganisms, and many small animals, air or water makes direct contact with the organism's cells or tissue fluids, and the processes of diffusion supply the organism with dioxygen (O2) and remove carbon dioxide (CO2). In larger animals the efficiency of gaseous exchange is improved by specialized respiratory organs, such as lungs and gills, which are ventilated by breathing mechanisms. http://purl.obolibrary.org/obo/PR_000001256 C-X-C chemokine receptor type 1 http://purl.obolibrary.org/obo/PR_000001226 high affinity interleukin-8 receptor A high affinity interleukin-8 receptor that is a translation product of the human CXCR1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000173 amniotic fluid http://purl.obolibrary.org/obo/UBERON_0000463 organism substance Amniotic fluid is a bodily fluid consisting of watery liquid surrounding and cushioning a growing fetus within the amnion. It allows the fetus to move freely without the walls of the uterus being too tight against its body. Buoyancy is also provided. The composition of the fluid changes over the course of gestation. Initially, amniotic fluid is similar to maternal plasma, mainly water with electrolytes. As the fetus develops, proteins, carbohydrates, lipids, phospholipids originating from the lungs, fetal cells, and urea are deposited in the fluid. http://purl.obolibrary.org/obo/PR_000001257 C-X-C chemokine receptor type 2 http://purl.obolibrary.org/obo/PR_000001226 high affinity interleukin-8 receptor A high affinity interleukin-8 receptor that is a translation product of the human CXCR2 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000174 excreta http://purl.obolibrary.org/obo/UBERON_0000463 organism substance A portion of organism substance that is the product of an excretion process that will be eliminated from the body. An excretion process is elimination by an organism of the waste products that arise as a result of metabolic activity. http://purl.obolibrary.org/obo/PR_000001281 ADP-ribosyl cyclase http://purl.obolibrary.org/obo/PR_000000001 protein A protein that contains the ADP-ribosyl cyclase domain (Pfam:PF02267). http://purl.obolibrary.org/obo/UBERON_0000179 haemolymphatic fluid http://purl.obolibrary.org/obo/UBERON_0006314 bodily fluid Circulating fluid that is part of the hemolymphoid system. Blood, lymph, interstitial fluid or its analogs. http://purl.obolibrary.org/obo/PR_000001288 B-cell receptor CD22 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CD22 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000200 gyrus http://purl.obolibrary.org/obo/UBERON_0034768 morphological feature A ridge on the cerebral cortex. It is generally surrounded by one or more sulci . http://purl.obolibrary.org/obo/PR_000001289 membrane-spanning 4-domains subfamily A member 1 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human MS4A1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000201 endothelial blood brain barrier http://purl.obolibrary.org/obo/UBERON_0000120 blood brain barrier A blood brain barrier that is composed of endothelial cells. http://purl.obolibrary.org/obo/PR_000001290 B7-related protein http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a member of a family that includes translation products of genes CD86, CD276, ICOSLG, and others. These are membrane-anchored proteins with a small intracellular domain and an extracellular domain with signal sequence, an Immunoglobulin V-set domain (Pfam:PF07686), and a CD80-like C2-set immunoglobulin domain (Pfam:PF08205). http://purl.obolibrary.org/obo/UBERON_0000202 glial blood brain barrier http://purl.obolibrary.org/obo/UBERON_0000120 blood brain barrier A blood brain barrier composed of glial cells. http://purl.obolibrary.org/obo/PR_000001292 C-type lectin domain family 4 member C http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CLEC4C gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000203 pallium http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain Dorsal part (roof region) of the telencephalon[GO]. http://purl.obolibrary.org/obo/PR_000001293 C-type lectin domain family 4 member K http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CD207 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001300 CD209 molecule http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CD209 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000204 ventral part of telencephalon http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain Ventral part (base region) of the telencephalon. http://purl.obolibrary.org/obo/PR_000001307 CD44 molecule http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CD44 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000209 tetrapod frontal bone http://purl.obolibrary.org/obo/UBERON_0011164 neurocranium bone The bone forming the forehead and roof of the eye orbit. http://purl.obolibrary.org/obo/PR_000001308 CD48 molecule http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CD48 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000211 ligament http://purl.obolibrary.org/obo/UBERON_0000062 organ Dense regular connective tissue connecting two or more adjacent skeletal elements or supporting an organ. http://purl.obolibrary.org/obo/PR_000001310 CD83 molecule http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CD83 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000218 vertebral arch of axis http://purl.obolibrary.org/obo/UBERON_0003861 neural arch A neural arch that is part of a vertebral bone 2. http://purl.obolibrary.org/obo/PR_000001313 E/P-selectin http://purl.obolibrary.org/obo/PR_000000001 protein A protein with core domain structure consisting of one lectin C-type domain (Pfam:PF00059), followed by one EGF domain (Pfam:PF00008), followed by 4-9 sushi domains (Pfam:PF00084), with the P-selectins generally being longer. http://purl.obolibrary.org/obo/UBERON_0000220 atlanto-occipital joint http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure The Atlanto-occipital joint (articulation between the atlas and the occipital bone) consists of a pair of condyloid joints. The atlanto-occipital joint is a synovial joint. The ligaments connecting the bones are: Two Articular capsules; Posterior atlantoöccipital membrane; Anterior atlantoöccipital membrane; Lateral atlantoöccipital. http://purl.obolibrary.org/obo/PR_000001318 L-selectin http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human SELL gene or a 1:1 ortholog thereof. It is a leukocyte adhesion receptor that play an important role in regulating the inflammatory response by mediating leukocyte tethering and rolling on adherent leukocytes. http://purl.obolibrary.org/obo/UBERON_0000305 amnion http://purl.obolibrary.org/obo/UBERON_0005631 extraembryonic membrane The thin innermost layer of the extraembryonic membranes that contains the amniotic fluid; the membrane forms a closed sac in which the embryo and later, the fetus, is suspended and protected. http://purl.obolibrary.org/obo/PR_000001319 SLAM family member 5 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CD84 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000307 blastula http://purl.obolibrary.org/obo/UBERON_0000922 embryo Organism at the blastula stage - an early stage of embryonic development in animals. It is produced by cleavage of a fertilized ovum and consists of a spherical layer of around 128 cells surrounding a central fluid-filled cavity called the blastocoel. The blastula follows the morula and precedes the gastrula in the developmental sequence. http://purl.obolibrary.org/obo/PR_000001320 alpha-(1,3)-fucosyltransferase http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a stand alone version of the Glycosyltransferase family 10 (fucosyltransferase) (Pfam:PF00852) domain. Proteins in this class may catalyze alpha-1,3 glycosidic linkages. http://purl.obolibrary.org/obo/UBERON_0000309 body wall http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision The external portion of an animal body derived from ectoderm and mesoderm layers that encloses the body cavity. http://purl.obolibrary.org/obo/PR_000001325 beta-1,3-glucuronyltransferase http://purl.obolibrary.org/obo/PR_000000001 protein A protein with a core domain structure consisting of a very small cytoplasmic domain followed by a transmembrane domain and a Glycosyltransferase family 43 (Pfam:PF03360) domain. http://purl.obolibrary.org/obo/UBERON_0000313 portion of cartilage tissue in tibia http://purl.obolibrary.org/obo/UBERON_0007391 pelvic appendage cartilage tissue Cartilage pertaining to the tibia. http://purl.obolibrary.org/obo/PR_000001326 bone marrow stromal antigen 2 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human BST2 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001327 cadherin http://purl.obolibrary.org/obo/PR_000000001 protein A protein that has a core domain structure of signal sequence, propeptide, five Cadherin domains (Pfam:PF00028), a transmembrane region, and a Cadherin cytoplasmic region (Pfam:PF01049). Cadherins function as adhesion molecules that mediate Ca2+-dependent cell-cell adhesion in solid tissues. http://purl.obolibrary.org/obo/UBERON_0000314 cecum mucosa http://purl.obolibrary.org/obo/UBERON_0000317 colonic mucosa A mucosa that is part of a cecum [Automatically generated definition]. http://purl.obolibrary.org/obo/PR_000001332 cell adhesion molecule CEACAM8 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CEACAM8 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000315 subarachnoid space http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space The space between the arachnoid and pia mater. http://purl.obolibrary.org/obo/PR_000001337 complement receptor type 1 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CR1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000316 cervical mucus http://purl.obolibrary.org/obo/UBERON_0000912 mucus A substance produced by the cervix and endocervical glands[BTO]. Thick acidic mucus that blocks the cervical os after mestruation[WP]. This 'infertile' mucus blocks spermatozoa from entering the uterus. http://purl.obolibrary.org/obo/PR_000001343 CD69 molecule http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CD69 gene or a 1:1 ortholog thereof. A type II transmembrane protein with a C-type lectin binding domain in the extracellular portion of the molecule. Involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets. http://purl.obolibrary.org/obo/UBERON_0000317 colonic mucosa http://purl.obolibrary.org/obo/UBERON_0001207 mucosa of large intestine Mucosa that is part of a colon. The mucosa of the colon is lined by a simple columnar epithelium with a thin brush border and numerous goblet cells. http://purl.obolibrary.org/obo/PR_000001344 ectonucleotide pyrophosphatase/phosphodiesterase family member 3 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human ENPP3 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000320 duodenal mucosa http://purl.obolibrary.org/obo/UBERON_0001204 mucosa of small intestine A mucosa that is part of a duodenum [Automatically generated definition]. http://purl.obolibrary.org/obo/PR_000001345 endoglin http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human ENG gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000323 late embryo http://purl.obolibrary.org/obo/UBERON_0000922 embryo An embryo that is at the late embryonic stage; this stage covers late steps of the embryogenesis with a fully formed embryo still developing before birth or egg hatching. http://purl.obolibrary.org/obo/PR_000001350 forkhead box protein P3 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human FOXP3 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000325 gastric gland http://purl.obolibrary.org/obo/UBERON_0003294 gland of foregut The branched tubular glands found in the mucosa of the fundus and body of the stomach which contain parietal cells that secrete hydrochloric acid and zymogenic cells that produce pepsin. http://purl.obolibrary.org/obo/PR_000001352 glycophorin http://purl.obolibrary.org/obo/PR_000000001 protein A protein that contains an extracellular Glycophorin A domain (Pfam:PF01102), followed by a single-pass transmembrane region and a small intracellular domain. A protein that is an integral protein of the red cell membrane. Proteins in this class are responsible for the molecular basis of the blood group antigens, surface markers on the outside of the red blood cell membrane. http://purl.obolibrary.org/obo/UBERON_0000326 pancreatic juice http://purl.obolibrary.org/obo/UBERON_0000456 secretion of exocrine gland Pancreatic juice is slightly alkaline and contains numerous enzymes and inactive enzyme precursors including alpha-amylase, chymotrypsinogen, lipase, procarboxypeptidase, proelastase, prophospholipase A2, ribonuclease, and trypsinogen. Its high concentration of bicarbonate ions helps to neutralize the acid from the stomach. http://purl.obolibrary.org/obo/PR_000001355 immunoglobulin gamma Fc receptor II/III/IV http://purl.obolibrary.org/obo/PR_000000001 protein A protein with a core domain architecture consisting of an extracellular domain containing two copies of the Immunoglobulin domain (Pfam:PF00047), followed by a single-pass transmembrane region and a small intracellular domain. The active protein is a low affinity receptor for immunoglobulin gamma chain Fc region. Human II-a, II-b, and II-c represent a recent gene expansion and are equally related to mouse II, III, and IV. Human III-A and III-B are closely related and closer to mouse IV than to mouse III. http://purl.obolibrary.org/obo/UBERON_0000328 gut wall http://purl.obolibrary.org/obo/UBERON_0000060 anatomical wall The wall of the digestive tract. This encompasses all parts of the digestive tract with the exception of the lumen (cavity). http://purl.obolibrary.org/obo/PR_000001356 immunoglobulin gamma Fc receptor I http://purl.obolibrary.org/obo/PR_000000001 protein A protein with a core domain architecture consisting of an extracellular domain containing two or three copies of the Immunoglobulin domain (Pfam:PF00047), followed by a single-pass transmembrane region and a small intracellular domain. http://purl.obolibrary.org/obo/PR_000001380 interleukin-2 receptor subunit alpha http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human IL2RA gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000331 ileal mucosa http://purl.obolibrary.org/obo/UBERON_0001204 mucosa of small intestine A mucosa that is part of a ileum [Automatically generated definition]. http://purl.obolibrary.org/obo/PR_000001381 interleukin-2 receptor subunit beta http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human IL2RB gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000332 yellow bone marrow http://purl.obolibrary.org/obo/UBERON_0002371 bone marrow Bone marrow in which the fat cells predominate in the meshes of the reticular network. http://purl.obolibrary.org/obo/PR_000001398 leukocyte immunoglobulin-like receptor subfamily A member 4 http://purl.obolibrary.org/obo/PR_000044780 leukocyte immunoglobulin-like receptor subfamily member A leukocyte immunoglobulin-like receptor subfamily member that is a translation product of the human LILRA4 gene or a 1:1 ortholog thereof. This gene is a member of a lineage-specific gene expansion in primates. http://purl.obolibrary.org/obo/PR_000001402 killer cell lectin-like receptor subfamily D member 1 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human KLRD1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000333 intestinal gland http://purl.obolibrary.org/obo/UBERON_0003408 gland of digestive tract A gland that is part of the intestinal mucosa. Examples include the intestinal crypts, duodenal gland[cjm]. http://purl.obolibrary.org/obo/PR_000001403 tetraspanin http://purl.obolibrary.org/obo/PR_000000001 protein A protein with four transmembrane domains, small intracellular amino- and carboxyl-terminal regions, and two extracellular loops, a small one (EC1) and a larger one (EC2) of about 100 residues. The EC2 loop contains at least four cysteine residues, including a highly conserved 'CCG' motif. http://purl.obolibrary.org/obo/UBERON_0000344 mucosa http://purl.obolibrary.org/obo/UBERON_0004923 organ component layer A lining of mostly endodermal origin, covered in epithelium, which is involved in absorption and secretion. They line various body cavities that are exposed to the external environment and internal organs. It is at several places continuous with skin: at the nostrils, the lips, the ears, the genital area, and the anus. The sticky, thick fluid secreted by the mucous membranes and gland is termed mucus. The term mucous membrane refers to where they are found in the body and not every mucous membrane secretes mucus[WP]. http://purl.obolibrary.org/obo/PR_000001408 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 http://purl.obolibrary.org/obo/PR_000001281 ADP-ribosyl cyclase An ADP-ribosyl cyclase that is a translation product of the human CD38 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001412 CD86 molecule http://purl.obolibrary.org/obo/PR_000001290 B7-related protein A B7-related protein that is a translation product of the human CD86 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000348 ophthalmic nerve http://purl.obolibrary.org/obo/UBERON_0011779 nerve of head region The sensory nerve subdivision of the trigeminal nerve that transmits sensory information from the orbit and its contents, the nasal cavity and the skin of the nose and forehead. http://purl.obolibrary.org/obo/PR_000001431 N-formyl peptide receptor http://purl.obolibrary.org/obo/PR_000001094 rhodopsin-like G-protein coupled receptor A rhodopsin-like G-protein coupled receptor that is a translation product of the human FPR1, FPR2, or FPR3 genes, 1:1 orthologs thereof, or a semi-ortholog thereof. The active form binds N-formyl methionyl peptides. http://purl.obolibrary.org/obo/UBERON_0000349 limbic system http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision A set of midline structures surrounding the brainstem of the mammalian brain, originally described anatomically, e.g., hippocampal formation, amygdala, hypothalamus, cingulate cortex. Although the original designation was anatomical, the limbic system has come to be associated with the system in the brain subserving emotional functions. As such, it is very poorly defined and doesn't correspond closely to the anatomical meaning any longer. [BirnLex]. http://purl.obolibrary.org/obo/PR_000001432 P-selectin http://purl.obolibrary.org/obo/PR_000001313 E/P-selectin An E/P-selectin that is a translation product of the human SELP gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000351 nuchal ligament http://purl.obolibrary.org/obo/UBERON_0008846 skeletal ligament A fibrous membrane, which, in the neck, represents the supraspinal ligaments of the upper vertebrae. http://purl.obolibrary.org/obo/PR_000001438 CD80 molecule http://purl.obolibrary.org/obo/PR_000001290 B7-related protein A B7-related protein that is a translation product of the human CD80 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000353 parenchyma http://purl.obolibrary.org/obo/UBERON_0000064 organ part Functional part of an organ in the body. This is in contrast to the stroma, which refers to the structural tissue of organs, being exactly, connective tissues. http://purl.obolibrary.org/obo/PR_000001440 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 http://purl.obolibrary.org/obo/PR_000001325 beta-1,3-glucuronyltransferase A beta-1,3-glucuronyltransferase that is a translation product of the human B3GAT1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000355 pharyngeal mucosa http://purl.obolibrary.org/obo/UBERON_0004785 respiratory system mucosa A mucosa that is part of a pharynx [Automatically generated definition]. http://purl.obolibrary.org/obo/PR_000001444 cadherin-5 http://purl.obolibrary.org/obo/PR_000001327 cadherin A cadherin that is a translation product of the human CDH5 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000358 blastocyst http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure The mammalian blastocyst is a hollow ball of cells containing two cell types, the inner cell mass and the trophectoderm[GO]. http://purl.obolibrary.org/obo/PR_000001447 cadherin-1 http://purl.obolibrary.org/obo/PR_000001327 cadherin A cadherin that is a translation product of the human CDH1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000361 red bone marrow http://purl.obolibrary.org/obo/UBERON_0002371 bone marrow The red vascular substance consisting of connective tissue and blood vessels, containing primitive blood cells, macrophages, megakaryocytes, and fat cells. Red marrow is found in the cavities of many bones. It manufactures and releases leukocytes and erythrocytes into the bloodstream. http://purl.obolibrary.org/obo/PR_000001456 alpha-(1,3)-fucosyltransferase 4 http://purl.obolibrary.org/obo/PR_000001320 alpha-(1,3)-fucosyltransferase An alpha-(1,3)-fucosyltransferase that is a translation product of the human FUT4 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000362 renal medulla http://purl.obolibrary.org/obo/UBERON_0000958 medulla of organ The inner portion of the kidney consisting of the renal pyramids. http://purl.obolibrary.org/obo/PR_000001460 glycophorin-A http://purl.obolibrary.org/obo/PR_000001352 glycophorin A glycophorin that is a translation product of the human GYPA gene or a 1:1 ortholog thereof. It is the major sialoglycoprotein of the erythrocyte membrane. Structurally, glycophorin A consists of an N-terminal extracellular domain, heavily glycosylated on Ser and threonine residues, followed by a transmembrane region and a C-terminal cytoplasmic domain. http://purl.obolibrary.org/obo/UBERON_0000365 urothelium http://purl.obolibrary.org/obo/UBERON_0005911 endo-epithelium An epithelial tissue layer that lines much of the urinary tract, including the renal pelvis, the ureters, the bladder, and parts of the urethra. http://purl.obolibrary.org/obo/PR_000001465 high affinity immunoglobulin gamma Fc receptor I http://purl.obolibrary.org/obo/PR_000001356 immunoglobulin gamma Fc receptor I An immunoglobulin gamma Fc receptor I that is a translation product of the human FCGR1A gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000369 corpus striatum http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain The corpus striatum (striated body) is a compound structure consisting of the caudate nucleus and the lentiform nucleus, which consists of the putamen and the globus pallidus[WP]. http://purl.obolibrary.org/obo/PR_000001479 low affinity immunoglobulin gamma Fc region receptor II http://purl.obolibrary.org/obo/PR_000001355 immunoglobulin gamma Fc receptor II/III/IV An immunoglobulin gamma Fc receptor II/III/IV that is a translation product of the mouse Fcgr2 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000371 syncytiotrophoblast http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure Extraembryonic cells of trophoblastic shell surrounding embryo, outside the cytotrophoblast layer, involved with implantation of the blastocyst by eroding extracellular matrix surrounding maternal endometrial cells at site of implantation, also contribute to villi. (dark staining, multinucleated). http://purl.obolibrary.org/obo/PR_000001481 low affinity immunoglobulin gamma Fc region receptor II-b http://purl.obolibrary.org/obo/PR_000001355 immunoglobulin gamma Fc receptor II/III/IV An immunoglobulin gamma Fc receptor II/III/IV that is a translation product of the human FCGR2B gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000375 mandibular nerve http://purl.obolibrary.org/obo/UBERON_0011779 nerve of head region The motor and sensory nerve subdivision of the trigeminal nerve that transmits sensory information from the auricle, the external acoustic meatus, tympanic membrane, temporal region, the cheek, the skin overlying the mandible, the anterior portion of the tongue, the floor of the mouth, lower teeth and gingiva and transmits motor information from the muscles of mastication, the mylohyoid muscle and digastric muscle and the muscles tensor tympani and tensor veli palatini. http://purl.obolibrary.org/obo/PR_000001483 low affinity immunoglobulin gamma Fc region receptor III http://purl.obolibrary.org/obo/PR_000001355 immunoglobulin gamma Fc receptor II/III/IV An immunoglobulin gamma Fc receptor II/III/IV that is a translation product of the mouse Fcgr3 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000376 hindlimb stylopod http://purl.obolibrary.org/obo/UBERON_0008784 lower limb segment The part of the hindlimb between pelvis and the knee, corresponding to the femur. http://purl.obolibrary.org/obo/PR_000001547 prostaglandin D2 receptor DP2 http://purl.obolibrary.org/obo/PR_000001549 prostanoid receptor A prostanoid receptor that is a translation product of the human PTGDR2 gene or a 1:1 ortholog thereof. The preferred ligand is 11-dehydro-thromboxane B2. This receptor is not closely related to the prostaglandin D2 receptor encoded by PGD2. http://purl.obolibrary.org/obo/UBERON_0000377 maxillary nerve http://purl.obolibrary.org/obo/UBERON_0011779 nerve of head region The sensory nerve subdivision of the trigeminal nerve that transmits sensory information from the palate, upper teeth and gingiva, the skin between the palpebral fissure and the mouth, and from the nasal cavity and maxillary sinuses. http://purl.obolibrary.org/obo/PR_000001549 prostanoid receptor http://purl.obolibrary.org/obo/PR_000001094 rhodopsin-like G-protein coupled receptor A rhodopsin-like G-protein coupled receptor that is a translation product of the human PTGDR, PTGDR2, PTGER1 to PTGER4, PTGFR, PTGIR, or TBXA2R genes, 1:1 orthologs thereof, or a semi-ortholog thereof. The active form binds prostanoids (prostaglandins and thromboxanes). http://purl.obolibrary.org/obo/UBERON_0000378 tongue muscle http://purl.obolibrary.org/obo/UBERON_0014892 skeletal muscle organ, vertebrate The muscular portion of the tongue. http://purl.obolibrary.org/obo/PR_000001551 relaxin family peptide receptor protein http://purl.obolibrary.org/obo/PR_000001094 rhodopsin-like G-protein coupled receptor A rhodopsin-like G-protein coupled receptor that is a translation product of the human RXFP1 to RXFP4 genes, 1:1 orthologs thereof, or a semi-ortholog thereof. The active form binds relaxins. http://purl.obolibrary.org/obo/UBERON_0000379 tracheal mucosa http://purl.obolibrary.org/obo/UBERON_0004785 respiratory system mucosa A mucosa that is part of a trachea. http://purl.obolibrary.org/obo/PR_000001562 vasopressin/oxytocin receptor http://purl.obolibrary.org/obo/PR_000001094 rhodopsin-like G-protein coupled receptor A rhodopsin-like G-protein coupled receptor that is a translation product of the human AVPR1A, AVPR1B, AVPR2, or OXTR genes, 1:1 orthologs thereof, or a semi-ortholog thereof. These receptors bind vasopressin or oxytocin or related nonapeptides. http://purl.obolibrary.org/obo/UBERON_0000383 musculature of body http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision The subdivision of the musculoskeletal system that consists of all the muscles of the body[VSAO, modified]. http://purl.obolibrary.org/obo/PR_000001580 fMet-Leu-Phe receptor http://purl.obolibrary.org/obo/PR_000001431 N-formyl peptide receptor An N-formyl peptide receptor that is a translation product of the human FPR1 gene or a 1:1 ortholog thereof. The preferred ligand is the peptide fMet-Leu-Phe, a bacterial peptide that acts as a chemoattractant in various pathophysiological conditions. http://purl.obolibrary.org/obo/UBERON_0000389 lens cortex http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure Tissue that surrounds the lens nucleus. http://purl.obolibrary.org/obo/PR_000001635 oxytocin receptor http://purl.obolibrary.org/obo/PR_000001562 vasopressin/oxytocin receptor A vasopressin/oxytocin receptor that is a translation product of the human OXTR gene or a 1:1 ortholog thereof. The preferred ligand is oxytocin. http://purl.obolibrary.org/obo/UBERON_0000390 lens nucleus http://purl.obolibrary.org/obo/UBERON_0034944 zone of organ The core of the crystalline lens, surrounded by the cortex. http://purl.obolibrary.org/obo/PR_000001666 relaxin receptor 1 http://purl.obolibrary.org/obo/PR_000001551 relaxin family peptide receptor protein A relaxin family peptide receptor protein that is a translation product of the human RXFP1 gene or a 1:1 ortholog thereof. This receptor is expressed in the brain, kidney, testis, placenta, uterus, ovary, adrenal, prostate, skin and heart. http://purl.obolibrary.org/obo/UBERON_0000395 cochlear ganglion http://purl.obolibrary.org/obo/UBERON_0001714 cranial ganglion The group of nerve cell bodies that conveys auditory sensation from the organ of Corti to the hindbrain and resides on the cochlear part of the vestibulocochlear nerve (eighth cranial nerve)[MP]. distributed to the hair cells of the spiral organ. The cochlear fibers arise in bipolar cells in the spiral ganglion in the modiolus. http://purl.obolibrary.org/obo/PR_000001753 transcription factor NF-kappa-B subunit http://purl.obolibrary.org/obo/PR_000000001 protein A protein that has a core domain composition consisting of a Rel homology domain (RHD) (Pfam:PF00554), an IPT/TIG domain (Pfam:PF01833), six copies of the Ankyrin repeat (Pfam:PF00023), a Death domain (Pfam:PF00531) and a C-terminal PEST region. http://purl.obolibrary.org/obo/UBERON_0000397 colonic epithelium http://purl.obolibrary.org/obo/UBERON_0001278 epithelium of large intestine An epithelium that is part of a colon [Automatically generated definition]. http://purl.obolibrary.org/obo/PR_000001785 prominin http://purl.obolibrary.org/obo/PR_000000001 protein A protein with core architecture consisting of one Prominin (Pfam:PF05478) domain. The prominins are an emerging family of proteins that, among the multispan membrane proteins, display a novel topology. Mouse and human prominin and prominin-like 1 are predicted to contain five membrane spanning domains, with an N-terminal domain exposed to the extracellular space followed by four, alternating small cytoplasmic and large extracellular, loops and a cytoplasmic C-terminal domain. http://purl.obolibrary.org/obo/UBERON_0000398 cartilage tissue of sternum http://purl.obolibrary.org/obo/UBERON_0003837 thoracic segment connective tissue Any portion of cartilage tissue that is part of the sternum. http://purl.obolibrary.org/obo/PR_000001786 prominin-1 http://purl.obolibrary.org/obo/PR_000001785 prominin A prominin that is a translation product of the human PROM1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000399 jejunal mucosa http://purl.obolibrary.org/obo/UBERON_0001204 mucosa of small intestine A mucosa that is part of a jejunum [Automatically generated definition]. http://purl.obolibrary.org/obo/PR_000001806 C-type lectin domain family 6 member A http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CLEC6A gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000400 jejunal epithelium http://purl.obolibrary.org/obo/UBERON_0013636 epithelium of intestinal villus An epithelium that is part of a jejunum. http://purl.obolibrary.org/obo/PR_000001807 C-type lectin domain family 7 member A http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CLEC7A gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000407 sympathetic trunk http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure One of a a paired bundle of nerve fibers plus ganglia that run from the base of the skull to the coccyx. http://purl.obolibrary.org/obo/PR_000001809 CD59-like glycoprotein http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CD59 gene, a 1:1 ortholog thereof, or pro-orthologs thereof. http://purl.obolibrary.org/obo/UBERON_0000409 serous gland http://purl.obolibrary.org/obo/UBERON_0002365 exocrine gland A gland in which the principal secretory cells are serous secreting cells. http://purl.obolibrary.org/obo/UBERON_0000410 bronchial mucosa http://purl.obolibrary.org/obo/UBERON_0004785 respiratory system mucosa A mucosa that is part of a bronchus [Automatically generated definition]. http://purl.obolibrary.org/obo/PR_000001810 CSF-1/PDGF receptor-type tyrosine-protein kinase http://purl.obolibrary.org/obo/PR_000000001 protein A protein with core architecture consisting of asignal sequence, 5 Ig-like domains, followed by a transmembrane sequence, followed by a Protein tyrosine kinase domain (Pfam:PF07714). However, only 1-3 of the Ig domains are detected by the Pfam HMMs in most of the sequences. Pfam:PF00047 is most common, but other members of the Ig domain clan, Pfam:PF07679 and Pfam:PF07686 can be identified instead. The fourth Ig domain lacks the disulfide-bonded cysteines. http://purl.obolibrary.org/obo/UBERON_0000412 dermal papilla http://purl.obolibrary.org/obo/UBERON_0000479 tissue A mesodermal signaling center of the hair follicle consisting of closely packed specialized mesenchymal fibroblasts. Framed by the enlarged bulb matrix in anagen. http://purl.obolibrary.org/obo/PR_000001813 adhesion G protein-coupled receptor E1 http://purl.obolibrary.org/obo/PR_000001087 adhesion G-protein coupled receptor An adhesion G-protein coupled receptor that is a translation product of the human ADGRE1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000414 mucous gland http://purl.obolibrary.org/obo/UBERON_0002365 exocrine gland A gland in which the principal secretory cells are mucus secreting cells. http://purl.obolibrary.org/obo/PR_000001820 MHC class II histocompatibility antigen alpha chain http://purl.obolibrary.org/obo/PR_000000001 protein A protein with core architecture consisting of a signal sequence, a Class II histocompatibility antigen, alpha domain (Pfam:PF00993) and an Immunoglobulin C1-set domain (Pfam:PF07654); these form the extracellular domain and are followed by a single-pass transmembrane region and a small cytoplasmic region. http://purl.obolibrary.org/obo/UBERON_0000415 artery wall http://purl.obolibrary.org/obo/UBERON_0035965 wall of blood vessel An anatomical wall that is part of an artery [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0000420 myoepithelium http://purl.obolibrary.org/obo/UBERON_0000488 atypical epithelium An epithelium consisting of myopethelial cells, which are contractile cells resembling smooth muscle cells that are present in glands, notably the mammary gland, and aid in secretion. This cell has long weaving dendritic processes containing myofilament[CL]. http://purl.obolibrary.org/obo/UBERON_0000424 gastric pit http://purl.obolibrary.org/obo/UBERON_0002553 anatomical cavity Gastric pits are indentations in the stomach which denote entrances to the gastric glands. They are deeper in the pylorus than they are in the other parts of the stomach. The human stomach has several million of these pits. http://purl.obolibrary.org/obo/UBERON_0000428 prostate epithelium http://purl.obolibrary.org/obo/UBERON_0005911 endo-epithelium The prostate epithelium. http://purl.obolibrary.org/obo/UBERON_0000429 enteric plexus http://purl.obolibrary.org/obo/UBERON_0001816 autonomic nerve plexus A plexus of autonomic nerve fibers within the wall of the digestive tube, and made up of the submucosal, myenteric, and subserosal plexuses; it contains visceral afferent fibers, sympathetic postganglionic fibers, parasympathetic preganglionic and postganglionic fibers, and parasympathetic postganglionic cell bodies. http://purl.obolibrary.org/obo/UBERON_0000437 arachnoid barrier layer http://purl.obolibrary.org/obo/UBERON_0004923 organ component layer The arachnoid barrier layer is a part of the arachnoid meningeal layer. It is formed by tight junctions between the endothelial cells of cerebral capillaries in the arachnoid mater. http://purl.obolibrary.org/obo/UBERON_0000439 arachnoid trabecula http://purl.obolibrary.org/obo/UBERON_0000440 trabecula The arachnoid trabeculae are delicate strands of connective tissue that loosely connect the two innermost layers of the meninges -- the arachnoid mater and the pia mater. They are found within the subarachnoid space where cerebrospinal fluid is also found. Embryologically, the trabeculae are the remnants of the common precursor that forms both the arachnoid and pial layers of the meninges. http://purl.obolibrary.org/obo/UBERON_0000440 trabecula http://purl.obolibrary.org/obo/UBERON_0000064 organ part A small, often microscopic, tissue element in the form of a small beam, strut or rod, generally having a mechanical function, and usually but not necessarily composed of dense collagenous tissue. On histological section, a trabecula can look like a septum, but in three dimensions they are topologically distinct, with trabeculae being roughly rod or pillar-shaped and septa being sheet-like. Trabeculae are usually composed of dense fibrous tissue, i.e. mainly of collagen, and in most cases provide mechanical strengthening or stiffening to a soft solid organ, such as the spleen. They can be composed of other materials, such as bone or muscle[WP]. http://purl.obolibrary.org/obo/PR_000001832 SIRP/SHPS-1 family protein http://purl.obolibrary.org/obo/PR_000000001 protein A protein with core architecture consisting of a signal sequence, one Immunoglobulin V-set domain (Pfam:PF07686), two Immunoglobulin C1-set domains (Pfam:PF07654), a single-pass transmembrane region and a very small cytoplasmic region. http://purl.obolibrary.org/obo/UBERON_0000442 right testicular vein http://purl.obolibrary.org/obo/UBERON_0001144 testicular vein A vein that drains the left pampiniform plexus and empties into the left renal vein. http://purl.obolibrary.org/obo/PR_000001833 SLAM family member 1 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human SLAMF1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000443 left testicular vein http://purl.obolibrary.org/obo/UBERON_0001144 testicular vein A vein that drains the right pampiniform plexus and empties into the inferior vena cava. http://purl.obolibrary.org/obo/PR_000001835 T-box transcription factor TBX21 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human TBX21 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000446 septum of telencephalon http://purl.obolibrary.org/obo/UBERON_0005401 cerebral hemisphere gray matter Gray matter structure located on the midline of the forebrain consisting of the septum pellucidum (in some species) and the septal nuclei (Heimer, 1996). http://purl.obolibrary.org/obo/PR_000001836 CD7 molecule http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CD7 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000454 cerebral subcortex http://purl.obolibrary.org/obo/UBERON_0000064 organ part The layer located below the cerebral cortex that includes the forebrain, midbrain and hindbrain. http://purl.obolibrary.org/obo/PR_000001838 T-cell surface glycoprotein CD1 http://purl.obolibrary.org/obo/PR_000000001 protein A protein with core architecture consisting of a signal sequence, an extracellular region with Class I Histocompatibility antigen, domains alpha 1 and alpha two (Pfam:PF00129) and an Immunoglobulin C1-set domain (Pfam:PF07654), a single-pass transmembrane region, and a very short cytoplasmic region. Forms a heterodimer with beta-2 microglobulin. http://purl.obolibrary.org/obo/UBERON_0000456 secretion of exocrine gland http://purl.obolibrary.org/obo/UBERON_0000463 organism substance A portion of organism substance that is produced by exocrine glands. http://purl.obolibrary.org/obo/PR_000001839 T-cell surface glycoprotein CD5 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CD5 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000457 cavernous artery http://purl.obolibrary.org/obo/UBERON_0001637 artery Any of several small branches of the internal carotid artery that supply the trigeminal ganglion and the walls of the cavernous and petrosal sinuses. http://purl.obolibrary.org/obo/PR_000001841 T-cell-specific surface glycoprotein CD28 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CD28 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001843 Thy-1 membrane glycoprotein http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human THY1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000459 uterine wall http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure An anatomical wall that is part of a uterus [Automatically generated definition]. http://purl.obolibrary.org/obo/PR_000001844 arginase-1 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human ARG1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000463 organism substance http://purl.obolibrary.org/obo/UBERON_0000465 material anatomical entity Material anatomical entity in a gaseous, liquid, semisolid or solid state; produced by anatomical structures or derived from inhaled and ingested substances that have been modified by anatomical structures as they pass through the body. http://purl.obolibrary.org/obo/PR_000001850 cathepsin K http://purl.obolibrary.org/obo/PR_000040662 cathepsin-like protease A cathepsin-like protease that is a translation product of the human CTSK gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space http://purl.obolibrary.org/obo/UBERON_0000466 immaterial anatomical entity Non-material anatomical entity of three dimensions, that is generated by morphogenetic or other physiologic processes; is surrounded by one or more anatomical structures; contains one or more organism substances or anatomical structures. http://purl.obolibrary.org/obo/PR_000001852 cytotoxic T-lymphocyte protein 4 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CTLA4 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000465 material anatomical entity http://purl.obolibrary.org/obo/UBERON_0001062 anatomical entity Anatomical entity that has mass. http://purl.obolibrary.org/obo/PR_000001854 ectonucleoside triphosphate diphosphohydrolase 1 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human ENTPD1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000466 immaterial anatomical entity http://purl.obolibrary.org/obo/UBERON_0001062 anatomical entity Anatomical entity that has no mass. http://purl.obolibrary.org/obo/PR_000001858 immunoglobulin iota chain http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human VPREB1 gene or a 1:1 ortholog thereof. The gene is recently and independently duplicated in mouse and rabbit, giving rise to very closely related VPREB2 genes in those species. The protein associates with the Ig-mu chain to form a molecular complex that is expressed only on the surface of pre-B-cells. http://purl.obolibrary.org/obo/UBERON_0000468 multicellular organism http://purl.obolibrary.org/obo/UBERON_0010000 multicellular anatomical structure Anatomical structure that is an individual member of a species and consists of more than one cell. http://purl.obolibrary.org/obo/PR_000001859 immunoglobulin lambda-like polypeptide 1 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human IGLL1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000471 compound organ component http://purl.obolibrary.org/obo/UBERON_0000481 multi-tissue structure Multi-tissue structure that is part of a compound organ. http://purl.obolibrary.org/obo/PR_000001860 inducible T-cell costimulator http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human ICOS gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision http://purl.obolibrary.org/obo/UBERON_0010000 multicellular anatomical structure Anatomical structure which is a subdivision of a whole organism, consisting of components of multiple anatomical systems, largely surrounded by a contiguous region of integument. http://purl.obolibrary.org/obo/PR_000001861 integrin beta http://purl.obolibrary.org/obo/PR_000000001 protein A protein with core architecture consisting of a large extracellular region containing one Integrin, beta chain domain (Pfam:PF00362), up to four EGF-like domains (Pfam:PF07974), and an Integrin beta tail domain (Pfam:PF07965), followed by a single-pass transmembrane region and a small cytoplasmic region often containing an Integrin beta cytoplasmic domain (Pfam:PF08725). http://purl.obolibrary.org/obo/UBERON_0000476 acellular anatomical structure http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure Anatomical structure that consists of cell parts and cell substances and together does not constitute a cell or a tissue. http://purl.obolibrary.org/obo/PR_000001865 interleukin-3 receptor class 2 alpha chain http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human IL3RA gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000477 anatomical cluster http://purl.obolibrary.org/obo/UBERON_0034923 disconnected anatomical group Anatomical group whose component anatomical structures lie in close proximity to each other. http://purl.obolibrary.org/obo/PR_000001867 interleukin-5 receptor subunit alpha http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human IL5RA gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000478 extraembryonic structure http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure A multicellular anatomical structure that is associated with an embryo and derived from the zygote from which it develops, but which does not contribute to the embryo proper or to structures that are part of the same organism after embryogenesis. http://purl.obolibrary.org/obo/PR_000001869 interleukin-7 receptor subunit alpha http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human IL7R gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000479 tissue http://purl.obolibrary.org/obo/UBERON_0010000 multicellular anatomical structure Multicellular anatomical structure that consists of many cells of one or a few types, arranged in an extracellular matrix such that their long-range organisation is at least partly a repetition of their short-range organisation. http://purl.obolibrary.org/obo/PR_000001874 KLRB1-like protein http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the KLRB1 gene or its closely related paralogs (KLRB1A-F). There are lineage-specific expansions in mouse and rat. http://purl.obolibrary.org/obo/UBERON_0000481 multi-tissue structure http://purl.obolibrary.org/obo/UBERON_0010000 multicellular anatomical structure Anatomical structure that has as its parts two or more portions of tissue of at least two different types and which through specific morphogenetic processes forms a single distinct structural unit demarcated by bona-fide boundaries from other distinct structural units of different types. http://purl.obolibrary.org/obo/PR_000001879 leukosialin http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human SPN gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000482 basal lamina of epithelium http://purl.obolibrary.org/obo/UBERON_0005764 acellular membrane Acellular anatomical structure that consists of a thin sheet of fibrous proteins that underlie and support the cells of an epithelium. It separates the cells of an epithelium from any underlying tissue. http://purl.obolibrary.org/obo/PR_000001880 low affinity immunoglobulin epsilon Fc receptor http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human FCER2 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000483 epithelium http://purl.obolibrary.org/obo/UBERON_0000479 tissue Portion of tissue, that consists of one or more layers of epithelial cells connected to each other by cell junctions and which is underlain by a basal lamina. Examples: simple squamous epithelium, glandular cuboidal epithelium, transitional epithelium, myoepithelium[CARO]. http://purl.obolibrary.org/obo/PR_000001883 lysosome-associated membrane protein http://purl.obolibrary.org/obo/PR_000000001 protein A protein with core architecture consisting of a Lysosome-associated membrane glycoprotein (Pfam:PF01299) domain. It is a single-pass type I membrane protein that shuttles between lysosomes, endosomes, and the plasma membrane. http://purl.obolibrary.org/obo/UBERON_0000484 simple cuboidal epithelium http://purl.obolibrary.org/obo/UBERON_0010077 cuboidal epithelium Unilaminar epithelium that consists of a single layer of cuboidal cells. http://purl.obolibrary.org/obo/PR_000001884 macrophage receptor MARCO http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human MARCO gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000485 simple columnar epithelium http://purl.obolibrary.org/obo/UBERON_0012274 columnar epithelium Unilaminar epithelium, which consists of a single layer of columnar cells. Examples: ciliated columnar epithelium, gastric epithelium, microvillus columnar epithelium.[FMA]. http://purl.obolibrary.org/obo/PR_000001885 macrophage scavenger receptor types I and II http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human MSR1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000486 multilaminar epithelium http://purl.obolibrary.org/obo/UBERON_0000483 epithelium Epithelium which consists of more than one layer of epithelial cells that may or may not be in contact with a basement membrane. Examples: keratinized stratified squamous epithelium, ciliated stratified columnar epithelium.[FMA]. http://purl.obolibrary.org/obo/PR_000001888 membrane alanyl aminopeptidase-like metallopeptidase http://purl.obolibrary.org/obo/PR_000000001 protein A protein with core architecture consisting of a Peptidase family M1 domain (Pfam:PF01433). http://purl.obolibrary.org/obo/PR_000001889 CD14 molecule http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CD14 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000487 simple squamous epithelium http://purl.obolibrary.org/obo/UBERON_0006914 squamous epithelium Unilaminar epithelium which consists of a single layer of squamous cells. Examples: pulmonary alveolar epithelium, endothelium.[FMA]. http://purl.obolibrary.org/obo/PR_000001892 CD33 molecule http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CD33 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000488 atypical epithelium http://purl.obolibrary.org/obo/UBERON_0000483 epithelium Epithelium that consists of epithelial cells not arranged in one ore more layers. http://purl.obolibrary.org/obo/PR_000001893 natural cytotoxicity triggering receptor 1 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human NCR1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000489 cavitated compound organ http://purl.obolibrary.org/obo/UBERON_0003103 compound organ Compound organ that contains one or more macroscopic anatomical spaces. http://purl.obolibrary.org/obo/PR_000001894 natural cytotoxicity triggering receptor 2 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human NCR2 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001896 natural killer cell receptor 2B4 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CD244 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000490 unilaminar epithelium http://purl.obolibrary.org/obo/UBERON_0000483 epithelium Epithelium which consists of a single layer of epithelial cells. Examples: endothelium, mesothelium, glandular squamous epithelium.[FMA]. http://purl.obolibrary.org/obo/PR_000001897 natural killer cell receptor NKG2 http://purl.obolibrary.org/obo/PR_000000001 protein A protein with core architecture consisting of an as yet unnamed domain in the amino-terminal half and a carboxyl-terminal Lectin C-type domain (Pfam:PF00059). http://purl.obolibrary.org/obo/UBERON_0000912 mucus http://purl.obolibrary.org/obo/UBERON_0006314 bodily fluid Mucus is a bodily fluid consisting of a slippery secretion of the lining of the mucous membranes in the body. It is a viscous colloid containing antiseptic enzymes (such as lysozyme) and immunoglobulins. Mucus is produced by goblet cells in the mucous membranes that cover the surfaces of the membranes. It is made up of mucins and inorganic salts suspended in water. http://purl.obolibrary.org/obo/PR_000001898 neprilysin http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human MME gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000913 interstitial fluid http://purl.obolibrary.org/obo/UBERON_0000463 organism substance Interstitial fluid is a bodily fluid consisting of a solution which bathes and surrounds the cells of multicellular animals. It is the main component of the extracellular fluid, which also includes plasma and transcellular fluid. http://purl.obolibrary.org/obo/PR_000001902 nuclear receptor ROR-gamma http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human RORC gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000916 abdomen http://purl.obolibrary.org/obo/UBERON_0009569 subdivision of trunk The subdivision of the vertebrate body between the thorax and pelvis. The ventral part of the abdomen contains the abdominal cavity and visceral organs. The dorsal part includes the abdominal section of the vertebral column. http://purl.obolibrary.org/obo/PR_000001903 paired box protein PAX-5 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human PAX5 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000922 embryo http://purl.obolibrary.org/obo/UBERON_0000468 multicellular organism Anatomical entity that comprises the organism in the early stages of growth and differentiation that are characterized by cleavage, the laying down of fundamental tissues, and the formation of primitive organs and organ systems. For example, for mammals, the process would begin with zygote formation and end with birth. For insects, the process would begin at zygote formation and end with larval hatching. For plant zygotic embryos, this would be from zygote formation to the end of seed dormancy. For plant vegetative embryos, this would be from the initial determination of the cell or group of cells to form an embryo until the point when the embryo becomes independent of the parent plant. http://purl.obolibrary.org/obo/PR_000001905 platelet glycoprotein 4 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CD36 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000923 germ layer http://purl.obolibrary.org/obo/UBERON_0010316 germ layer / neural crest A layer of cells produced during the process of gastrulation during the early development of the animal embryo, which is distinct from other such layers of cells, as an early step of cell differentiation. The three types of germ layers are the endoderm, ectoderm, and mesoderm. http://purl.obolibrary.org/obo/PR_000001907 platelet glycoprotein Ib alpha chain http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human GP1BA gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001919 programmed cell death protein 1 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human PDCD1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000924 ectoderm http://purl.obolibrary.org/obo/UBERON_0000923 germ layer Primary germ layer that is the outer of the embryo's three germ layers and gives rise to epidermis and neural tissue. http://purl.obolibrary.org/obo/PR_000001925 scavenger receptor cysteine-rich type 1 protein M130 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CD163 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001927 sialic acid-binding Ig-like lectin 5 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human SIGLEC5 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000925 endoderm http://purl.obolibrary.org/obo/UBERON_0000923 germ layer Primary germ layer that lies remote from the surface of the embryo and gives rise to internal tissues such as gut. http://purl.obolibrary.org/obo/PR_000001928 sialic acid-binding Ig-like lectin 6 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human SIGLEC6 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000926 mesoderm http://purl.obolibrary.org/obo/UBERON_0000923 germ layer The middle germ layer of the embryo, between the endoderm and ectoderm. http://purl.obolibrary.org/obo/PR_000001931 sialoadhesin http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human SIGLEC1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001932 signal transducer CD24 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CD24 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000930 stomodeum http://purl.obolibrary.org/obo/UBERON_0013522 subdivision of tube Anterior part of the embryonic digestive tract that develops into a mouth. The stomodeum includes as parts an invagination of the ectoderm and the stomodeal cavity. http://purl.obolibrary.org/obo/PR_000001935 syndecan-1 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human SDC1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000931 proctodeum http://purl.obolibrary.org/obo/UBERON_0016566 pit Inward fold on the surface of the embryonic ectoderm that develops into an ectodermal terminal part of the digestive tract. http://purl.obolibrary.org/obo/PR_000001937 tartrate-resistant acid phosphatase type 5 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human ACP5 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000933 chordate pharyngeal muscle http://purl.obolibrary.org/obo/UBERON_0001630 muscle organ A muscle that acts on the pharynx[WP, vetted]. http://purl.obolibrary.org/obo/PR_000001938 thrombomodulin-like receptor http://purl.obolibrary.org/obo/PR_000000001 protein A protein with core architecture consisting of a signal sequence, a Lectin C-type domain (Pfam:PF00059), 5 or 6 EGF-like domains (Pfam:PF00008, Pfam:PF09064, or Pfam:PF07645), a transmembrane region, and a small cytoplasmic region (36-51 amino acids). http://purl.obolibrary.org/obo/PR_000001941 trans-acting T-cell-specific transcription factor GATA-3 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human GATA3 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000936 posterior commissure http://purl.obolibrary.org/obo/UBERON_0011590 commissure of diencephalon Rounded band of white fibers crossing the middle line on the dorsal aspect of the upper end of the cerebral aqueduct. It is important in the bilateral pupillary light reflex. Its fibers acquire their medullary sheaths early, but their connections have not been definitely determined. Most of them have their origin in a nucleus, the nucleus of the posterior commissure (nucleus of Darkschewitsch), which lies in the central gray substance of the upper end of the cerebral aqueduct, in front of the nucleus of the oculomotor nerve. Some are probably derived from the posterior part of the thalamus and from the superior colliculus, whereas others are believed to be continued downward into the medial longitudinal fasciculus. The posterior commissure interconnects the pretectal nuclei, mediating the consensual pupillary light reflex[WP]. Diencephalic tract which is located in the vicinity of the dorsal diencephalon and mesencephalon and connects the pretectal nuclei. From Neuroanatomy of the Zebrafish Brain[ZFA]. http://purl.obolibrary.org/obo/PR_000001944 transcription factor PU.1 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human SPI1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000939 imaginal disc http://purl.obolibrary.org/obo/UBERON_0000481 multi-tissue structure One of the parts of a holometabolous insect larva that will become a portion of the outside of the adult insect during the pupal transformation. http://purl.obolibrary.org/obo/PR_000001945 transferrin receptor protein 1 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human TFRC gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000941 cranial nerve II http://purl.obolibrary.org/obo/UBERON_0034713 cranial neuron projection bundle Cranial nerve fiber tract which is comprised of retinal ganglion cell axons running posterior medially towards the optic chiasm, at which some of the axons cross the midline and after which the structure is termed the optic tract. Transmits visual information from the retina to the brain[ZFA]. http://purl.obolibrary.org/obo/PR_000001950 tumor necrosis factor ligand superfamily member 5 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CD40LG gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000951 rotator muscle of the vertebral column http://purl.obolibrary.org/obo/UBERON_0005174 dorsal region element Any of a number of short transversospinal muscles chiefly developed in cervical, lumbar, and thoracic regions, arising from the transverse process of one vertebra and inserted into the root of the spinous process of the next two or three vertebrae above, with nerve supply from the dorsal branches of the spinal nerve, and whose actions rotate the vertebral column. http://purl.obolibrary.org/obo/PR_000001954 tumor necrosis factor receptor superfamily member 11A http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human TNFRSF11A gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000956 cerebral cortex http://purl.obolibrary.org/obo/UBERON_0016548 central nervous system gray matter layer The thin layer of gray matter on the surface of the cerebral hemisphere that develops from the telencephalon. It consists of the neocortex (6 layered cortex or isocortex), the hippocampal formation and the olfactory cortex. http://purl.obolibrary.org/obo/PR_000001963 CD27 molecule http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CD27 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000957 lamina http://purl.obolibrary.org/obo/UBERON_0000479 tissue Any thin layer or plate. http://purl.obolibrary.org/obo/PR_000001968 tyrosine-protein phosphatase non-receptor type substrate 1 http://purl.obolibrary.org/obo/PR_000001832 SIRP/SHPS-1 family protein A SIRP/SHPS-1 family protein that is a translation product of the human SIRPA gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000958 medulla of organ http://purl.obolibrary.org/obo/UBERON_0000471 compound organ component Middle part of an organ, surrounded by the cortex. http://purl.obolibrary.org/obo/PR_000001969 urokinase plasminogen activator surface receptor http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human PLAUR gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000961 thoracic ganglion http://purl.obolibrary.org/obo/UBERON_0001807 paravertebral ganglion The thoracic ganglia are paravertebral ganglia. The thoracic portion of the sympathetic trunk typically has 12 thoracic ganglia. Emerging from the ganglia are thoracic splancic nerves (the cardiopulmonary, the greater, lesser, and least splanchic nerves) that help provide sympathetic innervation to abdominal structures. Also, the ganglia of the thoracic sympathetic trunk have both white and gray rami communicantes. The white rami carry sympathetic fibers arising in the spinal cord into the sympathetic trunk. [WP,unvetted]. http://purl.obolibrary.org/obo/PR_000001975 voltage-gated sodium channel subunit alpha http://purl.obolibrary.org/obo/PR_000044660 voltage-gated sodium channel protein A voltage-gated sodium channel protein that has a core architecture consisting of four similar domains (I-VI), each containing six transmembrane helices (S1-S6), with a pore loop between S5 and S6. The S4 segments contain positively charged amino acids at every third position and serve as voltage sensors. These large proteins (about 2000 amino acids) contain a unique Sodium ion transport-associated domain (Pfam:PF06512) located between two pairs of Ion transport protein domains (Pfam:PF00520). An IQ calmodulin-binding motif (Pfam:PF00612) may be found about 100 amino acids from the carboxyl end. http://purl.obolibrary.org/obo/UBERON_0000962 nerve of cervical vertebra http://purl.obolibrary.org/obo/UBERON_0001780 spinal nerve The cervical nerves are the spinal nerves from the cervical vertebrae. Although there are seven cervical vertebrae (C1-C7), there are eight cervical nerves (C1-C8). All nerves except C8 emerge above their corresponding vertebrae, while the C8 nerve emerges below the C7 vertebra. (In the other portions of the spine, the nerve emerges below the vertebra with the same name. Dorsal (posterior) distribution includes the greater occipital (C2) and third occipital (C3). Ventral (anterior) distribution includes the cervical plexus (C1-C4) and brachial plexus (C5-C8) [WP,unvetted]. http://purl.obolibrary.org/obo/PR_000001998 C-C motif chemokine 3/4 http://purl.obolibrary.org/obo/PR_000001808 C/C-C motif small inducible chemokine A C/C-C motif small inducible chemokine that is a translation product of the CCL3, CCL3L1/CCL3L3, or CCL4 gene. http://purl.obolibrary.org/obo/UBERON_0000971 ommatidium http://purl.obolibrary.org/obo/UBERON_0002536 arthropod sensillum The smallest morphological and functional unit of the compound eye that consists of a usually limited and often constant number of rhabdomeric photoreceptor cells, cornea-secreting epithelial cells, and interommatidial pigment cells, and may additionally contain crystalline cone cells. http://purl.obolibrary.org/obo/PR_000002001 receptor-type tyrosine-protein kinase FLT3 http://purl.obolibrary.org/obo/PR_000001810 CSF-1/PDGF receptor-type tyrosine-protein kinase A CSF-1/PDGF receptor-type tyrosine-protein kinase that is a translation product of the human FLT3 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000976 humerus http://purl.obolibrary.org/obo/UBERON_0015053 humerus endochondral element Paired endochondral long bone that extends between the pectoral girdle and the skeletal parts of the forelimb. [PHENOSCAPE:mah]. http://purl.obolibrary.org/obo/PR_000002015 MHC class II histocompatibility antigen alpha chain DRA http://purl.obolibrary.org/obo/PR_000001820 MHC class II histocompatibility antigen alpha chain An MHC class II histocompatibility antigen alpha chain that is a translation product of the human HLA-DRA gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000978 leg http://purl.obolibrary.org/obo/UBERON_0008784 lower limb segment The portion of the hindlimb that contains both the stylopod and zeugopod. http://purl.obolibrary.org/obo/PR_000002023 NKG2-A/NKG2-B type II integral membrane protein http://purl.obolibrary.org/obo/PR_000001897 natural killer cell receptor NKG2 A natural killer cell receptor NKG2 that is a translation product of the human KLRC1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000979 tibia http://purl.obolibrary.org/obo/UBERON_0015004 tibia endochondral element The major preaxial endochondral bone in the posterior zeugopod[Phenoscape]. http://purl.obolibrary.org/obo/PR_000002025 T-cell surface glycoprotein CD1a http://purl.obolibrary.org/obo/PR_000001838 T-cell surface glycoprotein CD1 A T-cell surface glycoprotein CD1 that is a translation product of the human CD1A gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000981 femur http://purl.obolibrary.org/obo/UBERON_0015052 femur endochondral element Endochondral longbone connecting the pelvic girdle with posterior zeugopodium skeleton.[VSAO, modified]. http://purl.obolibrary.org/obo/PR_000002027 T-cell surface glycoprotein CD1c http://purl.obolibrary.org/obo/PR_000001838 T-cell surface glycoprotein CD1 A T-cell surface glycoprotein CD1 that is a translation product of the human CD1C gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000982 skeletal joint http://purl.obolibrary.org/obo/UBERON_0004905 articulation Anatomical structure that consists of two or more adjacent skeletal structures, which may be interconnected by various types of tissue[VSAO]. http://purl.obolibrary.org/obo/PR_000002028 antigen-presenting glycoprotein CD1d http://purl.obolibrary.org/obo/PR_000001838 T-cell surface glycoprotein CD1 A T-cell surface glycoprotein CD1 that is a translation product of the human CD1D gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000983 metatarsus region http://purl.obolibrary.org/obo/UBERON_0009877 metapodium region A metapodium region that is part of a pes. http://purl.obolibrary.org/obo/PR_000002030 alpha-type platelet-derived growth factor receptor http://purl.obolibrary.org/obo/PR_000001810 CSF-1/PDGF receptor-type tyrosine-protein kinase A CSF-1/PDGF receptor-type tyrosine-protein kinase that is a translation product of the human PDGFRA gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000985 axillary vein http://purl.obolibrary.org/obo/UBERON_0001638 vein Vein that drains the axilla. http://purl.obolibrary.org/obo/PR_000002031 aminopeptidase N http://purl.obolibrary.org/obo/PR_000001888 membrane alanyl aminopeptidase-like metallopeptidase A membrane alanyl aminopeptidase-like metallopeptidase that is a translation product of the human ANPEP gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000988 pons http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain The part of the central nervous system lying between the medulla oblongata and the midbrain, ventral to the cerebellum. http://purl.obolibrary.org/obo/PR_000002037 complement component C1q receptor http://purl.obolibrary.org/obo/PR_000001938 thrombomodulin-like receptor A thrombomodulin-like receptor that is a translation product of the human CD93 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000993 oviduct http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure A tube or collection of tubes in an animal from the ovaries to the outside of the body. http://purl.obolibrary.org/obo/PR_000002039 glutamyl aminopeptidase http://purl.obolibrary.org/obo/PR_000001888 membrane alanyl aminopeptidase-like metallopeptidase A membrane alanyl aminopeptidase-like metallopeptidase that is a translation product of the human ENPEP gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0000999 ejaculatory duct http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure The Ejaculatory ducts (ductus ejaculatorii) are paired structures in male anatomy, about 2 cm in length. Each ejaculatory duct is formed by the union of the vas deferens with the duct of the seminal vesicle. They pass through the prostate, and empty into the urethra at the Colliculus seminalis. During ejaculation, semen passes through the ducts and exits the body via the penis[WP,unvetted]. http://purl.obolibrary.org/obo/PR_000002062 macrophage colony-stimulating factor 1 receptor http://purl.obolibrary.org/obo/PR_000001810 CSF-1/PDGF receptor-type tyrosine-protein kinase A CSF-1/PDGF receptor-type tyrosine-protein kinase that is a translation product of the human CSF1R gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000002064 macrosialin http://purl.obolibrary.org/obo/PR_000001883 lysosome-associated membrane protein A lysosome-associated membrane protein that is a translation product of the human CD68 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0001000 vas deferens http://purl.obolibrary.org/obo/UBERON_0005904 duct of male reproductive system A secretory duct that transports sperm from the testis. In mammals this is a continuation of the epididymis and ends in the prostatic urethra where it terminates to form ejaculatory duct. http://purl.obolibrary.org/obo/PR_000002065 mast/stem cell growth factor receptor http://purl.obolibrary.org/obo/PR_000001810 CSF-1/PDGF receptor-type tyrosine-protein kinase A CSF-1/PDGF receptor-type tyrosine-protein kinase that is a translation product of the human KIT gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0001005 respiratory airway http://purl.obolibrary.org/obo/UBERON_0004111 anatomical conduit An airway through which respiratory air passes in organisms. http://purl.obolibrary.org/obo/PR_000002097 sodium channel protein type 11 subunit alpha http://purl.obolibrary.org/obo/PR_000001975 voltage-gated sodium channel subunit alpha A voltage-gated sodium channel subunit alpha that is a translation product of the human SCN11A gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0001009 circulatory system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system Organ system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells, etc. to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis[WP]. http://purl.obolibrary.org/obo/PR_000002104 sodium channel protein type 9 subunit alpha http://purl.obolibrary.org/obo/PR_000001975 voltage-gated sodium channel subunit alpha A voltage-gated sodium channel subunit alpha that is a translation product of the human SCN9A gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0001013 adipose tissue http://purl.obolibrary.org/obo/UBERON_0011822 dense irregular connective tissue Portion of connective tissue composed of adipocytes enmeshed in areolar tissue. http://purl.obolibrary.org/obo/PR_000002105 thrombomodulin http://purl.obolibrary.org/obo/PR_000001938 thrombomodulin-like receptor A thrombomodulin-like receptor that is a translation product of the human THBD gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0001015 musculature http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision A subdivision of the muscular system corresponding to a subdisivision of an organism. http://purl.obolibrary.org/obo/UBERON_0001018 axon tract http://purl.obolibrary.org/obo/UBERON_0011215 central nervous system cell part cluster A group of axons linking two or more neuropils and having a common origin, termination[FBbt]. http://purl.obolibrary.org/obo/PR_000002112 vascular endothelial growth factor receptor 2 http://purl.obolibrary.org/obo/PR_000001971 vascular endothelial growth factor receptor A vascular endothelial growth factor receptor that is a translation product of the human KDR gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000002123 C-C motif chemokine 3 http://purl.obolibrary.org/obo/PR_000001998 C-C motif chemokine 3/4 A C-C motif chemokine 3/4 that is a translation product of the human CCL3 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0001019 nerve fasciculus http://purl.obolibrary.org/obo/UBERON_0000122 neuron projection bundle A slender neuron projection bundle[FBbt]; A bundle of anatomical fibers, as of muscle or nerve (American Heritage Dictionary 4th ed). http://purl.obolibrary.org/obo/PR_000002972 macrophage mannose receptor 1 http://purl.obolibrary.org/obo/PR_000001025 C-type lectin with multiple lectin domains A C-type lectin with multiple lectin domains that is a translation product of the human MRC1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0001020 nervous system commissure http://purl.obolibrary.org/obo/UBERON_0001018 axon tract Axon tract that crosses the midline of the central nervous system[NIF, modified]. In the context of Drosophila refers to a broad band of axons connecting equivalent neuropils each side of the brain[FBbt]. http://purl.obolibrary.org/obo/PR_000002976 Ly-6-like protein http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is the translation product of any of the LY6 genes (LY6A-LY6I). http://purl.obolibrary.org/obo/UBERON_0001021 nerve http://purl.obolibrary.org/obo/UBERON_0000122 neuron projection bundle An enclosed, cable-like bundle of axons in the peripheral nervous system originating in a nerve root in the central nervous system (or a condensed nervous structure) connecting with peripheral structures. http://purl.obolibrary.org/obo/PR_000002977 killer cell lectin-like receptor subfamily B member 1C http://purl.obolibrary.org/obo/PR_000001874 KLRB1-like protein A KLRB1-like protein that is a translation product of the mouse Klrb1c gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0001027 sensory nerve http://purl.obolibrary.org/obo/UBERON_0001021 nerve A nerve that transmits from sensory receptors on the surface of the body to the central nervous system. http://purl.obolibrary.org/obo/PR_000002978 lymphocyte antigen 6G http://purl.obolibrary.org/obo/PR_000002976 Ly-6-like protein An Ly-6-like protein that is a translation product of the mouse Ly6g gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0001033 gustatory system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system The sensory system for the sense of taste. http://purl.obolibrary.org/obo/PR_000002979 lymphocyte antigen 6A-2/6E-1 http://purl.obolibrary.org/obo/PR_000002976 Ly-6-like protein An Ly-6-like protein that is a translation product of the mouse Ly6a gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0001038 chordotonal organ http://purl.obolibrary.org/obo/UBERON_0000020 sense organ Chordotonal organs are arthropod sensory structures consisting of special sensilla called the scolopidia, which are mechano-transducers and respond mainly to stretch or flexion. In insects, they consist of bundles of internal sensilla, each of which has a cap cell, an enveloping cell and one or more sense cells. The distal end of the organ is usually attached to the cuticle of the body wall, marked by a pit, a thickened disc or a nodule of chitin, and the base of the organ is connected with the hypodermis, often by a special ligament. http://purl.obolibrary.org/obo/PR_000002980 lymphocyte antigen 6C2 http://purl.obolibrary.org/obo/PR_000002976 Ly-6-like protein An Ly-6-like protein that is a translation product of the mouse Ly6c2 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0001040 yolk sac http://purl.obolibrary.org/obo/UBERON_0007499 epithelial sac A sac-like expansion of the ventral wall of the intestine, narrowed into a yolk stalk near the body[Hyman's]. Membranous sac attached to an embryo, providing early nourishment in the form of yolk in bony fishes, sharks, reptiles, birds, and primitive mammals. It functions as the developmental circulatory system of the human embryo, before internal circulation begins. In the mouse, the yolk sac is the first site of blood formation, generating primitive macrophages and erythrocytes[WP]. http://purl.obolibrary.org/obo/PR_000002981 lymphocyte antigen 76 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A protein that is a translation product of the Ly76 gene in mouse. http://purl.obolibrary.org/obo/UBERON_0001041 foregut http://purl.obolibrary.org/obo/UBERON_0004921 subdivision of digestive tract Anterior subdivision of a digestive tract. http://purl.obolibrary.org/obo/PR_000003262 collagen alpha chain http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a component of collagen. Collagens are trimeric molecules in which each chain comprises a repeating Gly-X-Y triplet, in which X and Y can be any residue but are usually proline and hydroxyproline, respectively. This results in a left-handed helix that combines with other two to form a triple-helical structure. http://purl.obolibrary.org/obo/UBERON_0001042 chordate pharynx http://purl.obolibrary.org/obo/UBERON_0006562 pharynx A portion of the respiratory and digestive tracts; its distal limit is the superior part of the esophagus and it connects the nasal and oral cavities with the esophagus and larynx; it contains the valleculae and the pyriform recesses; its upper limits are the nasal cavity and cranial base.[FEED]. http://purl.obolibrary.org/obo/PR_000003263 collagen type I alpha chain http://purl.obolibrary.org/obo/PR_000003262 collagen alpha chain A collagen alpha chain that is a translation product of the human COL1A1 or COL1A2 genes, 1:1 orthologs thereof, or a semi-ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0001045 midgut http://purl.obolibrary.org/obo/UBERON_0004921 subdivision of digestive tract Middle subdivision of a digestive tract[CJM]. In vertebrates: The middle part of the alimentary canal from the stomach, or entrance of the bile duct, to, or including, the large intestine[GO]. http://purl.obolibrary.org/obo/PR_000003264 collagen alpha-1(I) chain http://purl.obolibrary.org/obo/PR_000003263 collagen type I alpha chain A collagen type I alpha chain that is a translation product of the human COL1A1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0001046 hindgut http://purl.obolibrary.org/obo/UBERON_0004921 subdivision of digestive tract The caudalmost subdivision of a digestive tract. http://purl.obolibrary.org/obo/PR_000003328 collagen alpha-1(III) chain http://purl.obolibrary.org/obo/PR_000003262 collagen alpha chain A collagen alpha chain that is a translation product of the human COL3A1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0001048 primordium http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure Primordia are populations of contiguous cells that are morphologically distinct and already correspond in extent to a later organ/tissue[FBbt, Hartenstein, V. (2004)]. http://purl.obolibrary.org/obo/PR_000003353 collagen alpha-1(VI) chain http://purl.obolibrary.org/obo/PR_000003386 collagen type VI alpha chain A collagen type VI alpha chain that is a translation product of the human COL6A1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0001049 neural tube http://purl.obolibrary.org/obo/UBERON_0016879 future central nervous system In the developing vertebrate, the neural tube is the embryo's precursor to the central nervous system, which comprises the brain and spinal cord. The neural groove gradually deepens as the neural folds become elevated, and ultimately the folds meet and coalesce in the middle line and convert the groove into a closed tube, the neural tube or neural canal (which strictly speaking is the center of the neural tube), the ectodermal wall of which forms the rudiment of the nervous system. [WP,unvetted]. http://purl.obolibrary.org/obo/PR_000003386 collagen type VI alpha chain http://purl.obolibrary.org/obo/PR_000003262 collagen alpha chain A collagen alpha chain that is a translation product of the human COL6A1, COL6A2, or COL6A3 genes, 1:1 orthologs thereof, or a semi-ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0001054 Malpighian tubule http://purl.obolibrary.org/obo/UBERON_0009773 renal tubule A tubule that extends from the posterior part of the digestive tract which absorbs solutes, water, and wastes from the surrounding hemolymph. Each tubule consists of a single layer of cells that is closed off at the distal end with the proximal end joining the alimentary canal at the junction between the midgut and hindgut[WP,modified]. http://purl.obolibrary.org/obo/PR_000018264 proteolytic cleavage product http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is produced as the result of proteolytic processing of a longer protein. http://purl.obolibrary.org/obo/UBERON_0001058 mushroom body http://purl.obolibrary.org/obo/UBERON_0000477 anatomical cluster Prominent lobed neuropils found in annelids and all arthropods except crustaceans. They are thought to be involved in olfactory associative learning and memory[MESH] Mushroom body neuropils are divided into calyces, pedunculus, and its subsequent lobes. In Drosophila these are the alpha, beta, and gamma lobes. http://purl.obolibrary.org/obo/PR_000018798 collagen alpha-1(I) chain proteolytic cleavage product http://purl.obolibrary.org/obo/PR_000018264 proteolytic cleavage product A collagen alpha-1(I) chain that has been processed by proteolytic cleavage. http://purl.obolibrary.org/obo/UBERON_0001063 flocculus http://purl.obolibrary.org/obo/UBERON_0027331 flocculonodular lobe, hemisphere portion The small lobe of the cerebellum at the posterior border of the middle cerebellar peduncle anterior to the biventer lobule that receives input from the inferior and medial vestibular nuclei and sends fibers back to the vestibular nuclei, and processes and integrates these signals to allow for the constant maintenance of balance. http://purl.obolibrary.org/obo/PR_000025796 integrin alpha http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is composed of a long N-terminal extracellular domain, a transmembrane domain and a short cytoplasmic C-terminal domain. The N-terminal domain contains beta-propeller repeats (interrupted by an A domain in a subset of integrins alpha), while the C-terminal domain contains a GFFxR motif. http://purl.obolibrary.org/obo/UBERON_0001064 ventral pancreatic duct http://purl.obolibrary.org/obo/UBERON_0000025 tube A duct joining the pancreas to the common bile duct to supply pancreatic juices which aid in digestion provided by the exocrine pancreas. The pancreatic duct joins the common bile duct just prior to the ampulla of Vater, after which both ducts perforate the medial side of the second portion of the duodenum at the major duodenal papilla. http://purl.obolibrary.org/obo/PR_000030035 G-protein coupled receptor http://purl.obolibrary.org/obo/PR_000000001 protein A protein that has G protein-coupled receptor (GPCR) activity. Each GPCR consists of a single polypeptide with an extracellular N-terminus, an intracellular C-terminus and seven hydrophobic transmembrane domains (TM1-TM7) linked by three extracellular loops (ECL1-ECL3) and three intracellular loops (ICL1-ICL3). GPCRs function as part of a heterotrimeric complex to transmit an extracellular signal across the membrane by activating an associated G-protein via the exchange of GDP for GTP on the alpha subunit. http://purl.obolibrary.org/obo/UBERON_0001066 intervertebral disk http://purl.obolibrary.org/obo/UBERON_0011135 intervertebral cartilage A pad of fibrocartilage between the articular surfaces of two successive vertebral centra which has nucleus pulposus at its core. http://purl.obolibrary.org/obo/PR_000036194 eukaryotic protein http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is encoded in the genome of some Eukaryota. http://purl.obolibrary.org/obo/UBERON_0001068 skin of back http://purl.obolibrary.org/obo/UBERON_0001085 skin of trunk A zone of skin that is part of a back [Automatically generated definition]. http://purl.obolibrary.org/obo/PR_000037069 glycoprotein http://purl.obolibrary.org/obo/PR_000000001 protein A protein that includes at least one glycosylated residue. http://purl.obolibrary.org/obo/UBERON_0001070 external carotid artery http://purl.obolibrary.org/obo/UBERON_0005396 carotid artery segment A terminal branch of the left or right common carotid artery which supplies oxygenated blood to to the throat, neck glands, tongue, face, mouth, ear, scalp and dura mater of the meninges[MP]. http://purl.obolibrary.org/obo/PR_000040662 cathepsin-like protease http://purl.obolibrary.org/obo/PR_000036194 eukaryotic protein A protein that is a translation product of some metazoan gene that encodes a signal peptide followed by a single Cathepsin propeptide inhibitor domain (Pfam:PF08246) followed by a single Papain family cysteine protease (Pfam:PF00112) domain at the C terminus. http://purl.obolibrary.org/obo/PR_000021081 bone marrow proteoglycan, signal peptide removed form http://purl.obolibrary.org/obo/PR_000013206 bone marrow proteoglycan A bone marrow proteoglycan that has had the signal peptide removed. http://purl.obolibrary.org/obo/UBERON_0001071 superficial cervical artery http://purl.obolibrary.org/obo/UBERON_0012320 cervical artery It ascends beneath the anterior margin of the trapezius, distributing branches to it, and to the neighboring muscles and lymph glands in the neck, and anastomosing with the superficial branch of the descending branch of the occipital artery. http://purl.obolibrary.org/obo/PR_000021082 bone marrow proteoglycan proteolytic cleavage product http://purl.obolibrary.org/obo/PR_000013206 bone marrow proteoglycan A bone marrow proteoglycan that has been processed by proteolytic cleavage. http://purl.obolibrary.org/obo/UBERON_0001072 inferior vena cava http://purl.obolibrary.org/obo/UBERON_0004087 vena cava A vein that carries deoxygenated blood from the lower half of the body into the right atrium of the heart. http://purl.obolibrary.org/obo/PR_000021083 proteoglycan 4 proteolytic cleavage product http://purl.obolibrary.org/obo/PR_000013208 proteoglycan 4 A proteoglycan 4 that has been processed by proteolytic cleavage. http://purl.obolibrary.org/obo/UBERON_0001073 ileocecal junction http://purl.obolibrary.org/obo/UBERON_8410024 intestinal junction A point along the course of the gastrointestinal tract where the small intestine (ileum) ends as it opens into the cecal portion of the large intestine; occurs usually within the iliac fossa, demarcated internally as the ileocecal orifice. http://purl.obolibrary.org/obo/PR_000021172 parathyroid hormone-related protein proteolytic cleavage product http://purl.obolibrary.org/obo/PR_000013433 parathyroid hormone-related protein A parathyroid hormone-related protein that has been processed by proteolytic cleavage. http://purl.obolibrary.org/obo/UBERON_0001074 pericardial cavity http://purl.obolibrary.org/obo/UBERON_0035809 serous cavity A potential space between the visceral and parietal layers of the pericardium. http://purl.obolibrary.org/obo/PR_000021468 sonic hedgehog protein proteolytic cleavage product http://purl.obolibrary.org/obo/PR_000018264 proteolytic cleavage product A sonic hedgehog protein that has been processed by proteolytic cleavage. http://purl.obolibrary.org/obo/UBERON_0001075 bony vertebral centrum http://purl.obolibrary.org/obo/UBERON_0016491 vertebral centrum element Ossified form of a vertebral centrum, a skeletal element that functionally replaces the notochord[VSAP,modified]. http://purl.obolibrary.org/obo/PR_000021578 somatostatin proteolytic cleavage product http://purl.obolibrary.org/obo/PR_000018264 proteolytic cleavage product A somatostatin that has been processed by proteolytic cleavage. http://purl.obolibrary.org/obo/UBERON_0001076 neural spine http://purl.obolibrary.org/obo/UBERON_0006061 process of vertebra An extension of a neural arches dorsal to the neural canal[TAO,modified]. http://purl.obolibrary.org/obo/PR_000021619 protachykinin-1 proteolytic cleavage product http://purl.obolibrary.org/obo/PR_000018264 proteolytic cleavage product A protachykinin-1 that has been processed by proteolytic cleavage. http://purl.obolibrary.org/obo/UBERON_0001077 transverse process of vertebra http://purl.obolibrary.org/obo/UBERON_0006061 process of vertebra The transverse or costal processes of a vertebra, two in number, project one at either side from the point where the lamina joins the pedicle, between the superior and inferior articular processes. They serve for the attachment of muscles and ligaments. [WP,unvetted]. http://purl.obolibrary.org/obo/PR_000021620 tachykinin-3 proteolytic cleavage product http://purl.obolibrary.org/obo/PR_000018264 proteolytic cleavage product A tachykinin-3 that has been processed by proteolytic cleavage. http://purl.obolibrary.org/obo/UBERON_0001081 endocardium of ventricle http://purl.obolibrary.org/obo/UBERON_0002165 endocardium Endocardium that is part of the cardiac ventricle. http://purl.obolibrary.org/obo/PR_000021826 vasoactive intestinal polypeptides proteolytic cleavage product http://purl.obolibrary.org/obo/PR_000018264 proteolytic cleavage product A VIP peptides that has been processed by proteolytic cleavage. http://purl.obolibrary.org/obo/UBERON_0001082 epicardium of ventricle http://purl.obolibrary.org/obo/UBERON_0002348 epicardium An epicardial layer that lines a cardiac ventricle. http://purl.obolibrary.org/obo/UBERON_0001083 myocardium of ventricle http://purl.obolibrary.org/obo/UBERON_0002349 myocardium Muscular layer of the cardiac ventricle composed of a compact myocardial layer surrounding the trabecular layer. http://purl.obolibrary.org/obo/PR_000022003 bone marrow proteoglycan isoform 1 http://purl.obolibrary.org/obo/PR_000013206 bone marrow proteoglycan A bone marrow proteoglycan that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P13727-1 or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0001084 skin of head http://purl.obolibrary.org/obo/UBERON_0012180 head or neck skin A zone of skin that is part of a head [Automatically generated definition]. http://purl.obolibrary.org/obo/PR_000022006 eosinophil granule major basic protein http://purl.obolibrary.org/obo/PR_000025466 bone marrow proteoglycan isoform 1, signal peptide removed form A bone marrow proteoglycan isoform 1, signal peptide removed form that has had the acidic propeptide removed. http://purl.obolibrary.org/obo/UBERON_0001085 skin of trunk http://purl.obolibrary.org/obo/UBERON_0000014 zone of skin A zone of skin that is part of a trunk [Automatically generated definition]. http://purl.obolibrary.org/obo/PR_000025403 T-cell surface glycoprotein CD8 alpha chain isoform 1 http://purl.obolibrary.org/obo/PR_000001084 T-cell surface glycoprotein CD8 alpha chain A T-cell surface glycoprotein CD8 alpha chain that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P01732-1 or a 1:1 ortholog thereof. Having a single-pass transmembrane domain, this form is membrane bound. http://purl.obolibrary.org/obo/UBERON_0001087 pleural fluid http://purl.obolibrary.org/obo/UBERON_0036244 secretion of serous membrane Transudate contained in the pleural cavity. http://purl.obolibrary.org/obo/PR_000025405 T-cell surface glycoprotein CD8 beta chain isoform 1 http://purl.obolibrary.org/obo/PR_000001085 T-cell surface glycoprotein CD8 beta chain A T-cell surface glycoprotein CD8 beta chain that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P10966-1 or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0001088 urine http://purl.obolibrary.org/obo/UBERON_0000174 excreta Excretion that is the output of a kidney. http://purl.obolibrary.org/obo/PR_000025406 T-cell surface glycoprotein CD8 alpha chain isoform 1, signal peptide removed form http://purl.obolibrary.org/obo/PR_000025403 T-cell surface glycoprotein CD8 alpha chain isoform 1 A T-cell surface glycoprotein CD8 alpha chain isoform 1 that has had the signal peptide removed to yield the mature form. http://purl.obolibrary.org/obo/UBERON_0001089 sweat http://purl.obolibrary.org/obo/UBERON_0006314 bodily fluid Secretion produced by a sweat gland. http://purl.obolibrary.org/obo/PR_000025407 T-cell surface glycoprotein CD8 beta chain isoform 1, signal peptide removed form http://purl.obolibrary.org/obo/PR_000025405 T-cell surface glycoprotein CD8 beta chain isoform 1 A T-cell surface glycoprotein CD8 beta chain isoform 1 that has had the signal peptide removed to yield the mature form. http://purl.obolibrary.org/obo/UBERON_0001090 synovial fluid http://purl.obolibrary.org/obo/UBERON_0007794 secretion of serous gland Joint fluid is a transudate of plasma that is actively secreted by synovial cells. http://purl.obolibrary.org/obo/PR_000025408 T-cell surface glycoprotein CD8 alpha chain isoform 1, signal peptide removed glycosylated form http://purl.obolibrary.org/obo/PR_000025406 T-cell surface glycoprotein CD8 alpha chain isoform 1, signal peptide removed form A T-cell surface glycoprotein CD8 alpha chain isoform 1, signal peptide removed form that includes at least one glycosylated residue. http://purl.obolibrary.org/obo/UBERON_0001092 vertebral bone 1 http://purl.obolibrary.org/obo/UBERON_0002412 vertebra The first vertebral bone in the vertebral column. http://purl.obolibrary.org/obo/PR_000025409 T-cell surface glycoprotein CD8 beta chain isoform 1, signal peptide removed glycosylated form http://purl.obolibrary.org/obo/PR_000025407 T-cell surface glycoprotein CD8 beta chain isoform 1, signal peptide removed form A T-cell surface glycoprotein CD8 beta chain isoform 1, signal peptide removed form that includes at least one glycosylated residue. http://purl.obolibrary.org/obo/UBERON_0001093 vertebral bone 2 http://purl.obolibrary.org/obo/UBERON_0002412 vertebra The second vertebral bone in the vertebral column. http://purl.obolibrary.org/obo/PR_000025420 collagen alpha-1(VI) chain proteolytic cleavage product http://purl.obolibrary.org/obo/PR_000018264 proteolytic cleavage product A collagen alpha-1(VI) chain that has been processed by proteolytic cleavage. http://purl.obolibrary.org/obo/UBERON_0001094 sacral vertebra http://purl.obolibrary.org/obo/UBERON_0015010 sacral vertebra endochondral element A vertebra bone that is part of the sacral region of the vertebral column. http://purl.obolibrary.org/obo/PR_000025455 CD2 molecule proteolytic cleavage product http://purl.obolibrary.org/obo/PR_000018264 proteolytic cleavage product A CD2 molecule that has been processed by proteolytic cleavage. http://purl.obolibrary.org/obo/UBERON_0001095 caudal vertebra http://purl.obolibrary.org/obo/UBERON_0018142 caudal vertebra endochondral element Any vertebral bone that is part of the caudal region of the vertebral column (tail or coccyx). http://purl.obolibrary.org/obo/PR_000025466 bone marrow proteoglycan isoform 1, signal peptide removed form http://purl.obolibrary.org/obo/PR_000022003 bone marrow proteoglycan isoform 1 A bone marrow proteoglycan isoform 1 that has had the signal peptide removed. http://purl.obolibrary.org/obo/UBERON_0001096 wall of esophagus http://purl.obolibrary.org/obo/UBERON_0000328 gut wall An anatomical wall that is part of a esophagus [Automatically generated definition]. http://purl.obolibrary.org/obo/PR_000025670 killer cell lectin-like receptor subfamily B member 1 http://purl.obolibrary.org/obo/PR_000001874 KLRB1-like protein A KLRB1-like protein that is a translation product of the human KLRB1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0001100 pectoralis minor http://purl.obolibrary.org/obo/UBERON_0001495 pectoral muscle The Pectoralis minor is a thin, triangular muscle, situated at the upper part of the chest, beneath the Pectoralis major. [WP,unvetted]. http://purl.obolibrary.org/obo/PR_000027222 CALCA gene translation product http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CALCA gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0001105 clavicle bone http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure A paired dermal or endochondral bone that is part of the pectoral girdle. The clavicle may be in contact with the interclavicle or coracoid and forms an attachment site for pectoral musculature. [PHENOSCAPE:ad]. http://purl.obolibrary.org/obo/PR_000027223 CALCA gene translation product (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A CALCA gene translation product that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0001112 latissimus dorsi muscle http://purl.obolibrary.org/obo/UBERON_0034908 scapular muscle The latissimus dorsi is the larger, flat, dorso-lateral muscle on the trunk, posterior to the arm, and partly covered by the trapezius on its median dorsal region. [WP,unvetted]. http://purl.obolibrary.org/obo/PR_000027226 calcitonin gene-related peptide 1 http://purl.obolibrary.org/obo/PR_000027222 CALCA gene translation product A CALCA gene translation product that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P06881-1 or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0001113 lobe of liver http://purl.obolibrary.org/obo/UBERON_0009912 anatomical lobe Traditional gross anatomy divided the liver into four lobes based on surface features. The falciform ligament is visible on the front (anterior side) of the liver. This divides the liver into a left anatomical lobe, and a right anatomical lobe. http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein http://purl.obolibrary.org/obo/PR_000036194 eukaryotic protein A protein that is encoded in the genome of Mus musculus. http://purl.obolibrary.org/obo/UBERON_0001114 right lobe of liver http://purl.obolibrary.org/obo/UBERON_0001113 lobe of liver The right lobe is much larger than the left; the proportion between them being as six to one. It occupies the right hypochondrium, and is separated from the left lobe on its upper surface by the falciform ligament; on its under and posterior surfaces by the left sagittal fossa; and in front by the umbilical notch. It is of a somewhat quadrilateral form, its under and posterior surfaces being marked by three fossæ: the porta and the fossæ for the gall-bladder and inferior vena cava, which separate its left part into two smaller lobes; the quadrate and caudate lobes. [WP,unvetted]. http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein http://purl.obolibrary.org/obo/PR_000036194 eukaryotic protein A protein that is encoded in the genome of Homo sapiens. http://purl.obolibrary.org/obo/UBERON_0001115 left lobe of liver http://purl.obolibrary.org/obo/UBERON_0001113 lobe of liver The left lobe is smaller and more flattened than the right. It is situated in the epigastric and left hypochondriac regions. Its upper surface is slightly convex and is moulded on to the diaphragm; its under surface presents the gastric impression and omental tuberosity. [WP,unvetted]. http://purl.obolibrary.org/obo/PR_P10747 T-cell-specific surface glycoprotein CD28 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A T-cell-specific surface glycoprotein CD28 that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001118 lobe of thyroid gland http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure A lobe of tissue that is part of a thyroid gland. http://purl.obolibrary.org/obo/PR_P11215 integrin alpha-M (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein An integrin alpha-M that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001119 right lobe of thyroid gland http://purl.obolibrary.org/obo/UBERON_0001118 lobe of thyroid gland A lobe of thyroid gland that is in the right side of a thyroid gland. http://purl.obolibrary.org/obo/UBERON_0001120 left lobe of thyroid gland http://purl.obolibrary.org/obo/UBERON_0001118 lobe of thyroid gland A lobe of thyroid gland that is in the left side of a thyroid gland. http://purl.obolibrary.org/obo/PR_P38570 integrin alpha-E (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein An integrin alpha-E that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001125 serratus ventralis http://purl.obolibrary.org/obo/UBERON_0034908 scapular muscle The serratus ventralis is a muscle that originates on the surface of the upper eight or nine ribs at the side of the chest and inserts along the entire anterior length of the medial border of the scapula. [WP,unvetted]. http://purl.obolibrary.org/obo/PR_O95817 BAG family molecular chaperone regulator 3 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A BAG family molecular chaperone regulator 3 that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001131 vertebral foramen http://purl.obolibrary.org/obo/UBERON_0004111 anatomical conduit A foramen within a vertebral element through which the spinal cord runs. It is formed by the anterior segment, and the posterior part, the vertebral arch. http://purl.obolibrary.org/obo/PR_P01732 T-cell surface glycoprotein CD8 alpha chain (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A T-cell surface glycoprotein CD8 alpha chain that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001133 cardiac muscle tissue http://purl.obolibrary.org/obo/UBERON_8600006 visceral striated muscle tissue Muscle tissue composed of cardiac muscle cells, forming the muscles of the heart[ZFA,modified]. http://purl.obolibrary.org/obo/PR_P02452 collagen alpha-1(I) chain (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A collagen alpha-1(I) chain that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001136 mesothelium http://purl.obolibrary.org/obo/UBERON_0012275 meso-epithelium Simple squamous epithelium of mesodermal origin which lines serous membranes. Examples: mesothelium of pleura, mesothelium of peritoneum[FMA]. Wikipedia: The mesothelium is a membrane that forms the lining of several body cavities: the pleura (thoracal cavity), peritoneum (abdominal cavity including the mesentery) and pericardium (heart sac). Mesothelial tissue also surrounds the male internal reproductive organs (the tunica vaginalis testis) and covers the internal reproductive organs of women (the tunica serosa uteri). http://purl.obolibrary.org/obo/PR_P02461 collagen alpha-1(III) chain (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A collagen alpha-1(III) chain that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001137 dorsum http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision A major subdivision of an organism that is the entire part of the organism dorsal to a horizontal plane and bounded on one side by the same transverse plane. In vertebrares this includes the vertebral column.. http://purl.obolibrary.org/obo/PR_P02786 transferrin receptor protein 1 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A transferrin receptor protein 1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001138 superior mesenteric vein http://purl.obolibrary.org/obo/UBERON_0005617 mesenteric vein In anatomy, the superior mesenteric vein (SMV) is a blood vessel that drains blood from the small intestine. At its termination behind the neck of the pancreas, the SMV combines with the splenic vein to form the hepatic portal vein. The SMV lies to the right of the similarly named artery, the superior mesenteric artery, which originates from the abdominal aorta. [WP,unvetted]. http://purl.obolibrary.org/obo/UBERON_0001139 common iliac vein http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure A vein that drains the pelvis and lower limbs into the inferior vena cava. http://purl.obolibrary.org/obo/PR_P03372 estrogen receptor (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein An estrogen receptor that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001140 renal vein http://purl.obolibrary.org/obo/UBERON_0001638 vein Either of the pair of major vessels which arise from the renal hilus and return blood from the kidneys, suprarenal gland and the ureter to the inferior vena cava. http://purl.obolibrary.org/obo/PR_P06126 T-cell surface glycoprotein CD1a (human) http://purl.obolibrary.org/obo/PR_000036947 T-cell surface glycoprotein CD1 (human) A T-cell surface glycoprotein CD1a that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001141 right renal vein http://purl.obolibrary.org/obo/UBERON_0001140 renal vein A renal vein that drains the right kidney. http://purl.obolibrary.org/obo/PR_P06307 cholecystokinin (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A cholecystokinin that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001142 left renal vein http://purl.obolibrary.org/obo/UBERON_0001140 renal vein A renal vein that drains the left kidney. http://purl.obolibrary.org/obo/PR_P06729 T-cell surface antigen CD2 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A CD2 molecule that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001143 hepatic vein http://purl.obolibrary.org/obo/UBERON_0015796 liver blood vessel Vein that carries blood away from the liver[ZFA]. http://purl.obolibrary.org/obo/PR_P07451 carbonic anhydrase 3 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A carbonic anhydrase 3 that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001144 testicular vein http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure A vein that carries deoxygenated blood from a single male gonad. It is the male equivalent of the ovarian vein, and is the venous counterpart of the testicular artery. It is a paired vein, with one supplying each testis. http://purl.obolibrary.org/obo/PR_P07766 T-cell surface glycoprotein CD3 epsilon chain (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A CD3 epsilon that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001145 ovarian vein http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure A vein that carries deoxygenated blood from its corresponding ovary to inferior vena cava or one of its tributaries. http://purl.obolibrary.org/obo/PR_P07949 proto-oncogene tyrosine-protein kinase receptor Ret (human) http://purl.obolibrary.org/obo/PR_000013895 proto-oncogene tyrosine-protein kinase receptor Ret A proto-oncogene tyrosine-protein kinase receptor Ret that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001146 suprarenal vein http://purl.obolibrary.org/obo/UBERON_0001638 vein A vein that drains the adrenal gland. http://purl.obolibrary.org/obo/PR_P08473 neprilysin (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A neprilysin that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001152 cystic duct http://purl.obolibrary.org/obo/UBERON_0003703 extrahepatic bile duct The tubular structure that conducts gall bladder contents from the gall bladder to the common bile duct. http://purl.obolibrary.org/obo/PR_P08670 vimentin (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A vimentin that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001167 wall of stomach http://purl.obolibrary.org/obo/UBERON_0000328 gut wall The layered structure that makes up the stomach, typiclly consists of a serous coat, a muscular coat, a mucous membrane, and other tissue layers in between. http://purl.obolibrary.org/obo/PR_P09581 macrophage colony-stimulating factor 1 receptor (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A macrophage colony-stimulating factor 1 receptor that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0001168 wall of small intestine http://purl.obolibrary.org/obo/UBERON_0001262 wall of intestine An anatomical wall that is part of a small intestine [Automatically generated definition]. http://purl.obolibrary.org/obo/PR_P10147 C-C motif chemokine 3 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A C-C motif chemokine 3 that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001169 wall of large intestine http://purl.obolibrary.org/obo/UBERON_0001262 wall of intestine An anatomical wall that is part of a large intestine [Automatically generated definition]. http://purl.obolibrary.org/obo/PR_P10242 transcriptional activator Myb (human) http://purl.obolibrary.org/obo/PR_000010799 myb proto-oncogene protein A myb proto-oncogene protein that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001170 mesentery of small intestine http://purl.obolibrary.org/obo/UBERON_0007826 peritoneal mesentery The peritoneum responsible for connecting the jejunum and ileum (parts of the small intestine) to the back wall of the abdomen. Between the two sheets of peritoneum are blood vessels, lymph vessels, and nerves. This allows these parts of the small intestine to move relatively freely within the abdominopelvic cavity. The brain, however, cannot map sensation accurately, so sensation is usually referred to the midline, an example of referred pain[WP]. http://purl.obolibrary.org/obo/PR_P10966 T-cell surface glycoprotein CD8 beta chain (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A T-cell surface glycoprotein CD8 beta chain that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001171 portal lobule http://purl.obolibrary.org/obo/UBERON_0009911 lobule The triangular region on the periphery of the liver lobules that contain a bile duct and a terminal branch of the hepatic artery and portal vein, and may also include a lymphatic vessel. http://purl.obolibrary.org/obo/PR_P12107 collagen alpha-1(XI) chain (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A collagen alpha-1(XI) chain that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001172 hepatic acinus http://purl.obolibrary.org/obo/UBERON_0011858 acinus of exocrine gland The functional unit of the liver, consisting of a mass of hepatocytes from adjacent liver lobules aligned around the hepatic arterioles and portal venules just as they anastomose into sinusoids. http://purl.obolibrary.org/obo/PR_P12109 collagen alpha-1(VI) chain (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A collagen alpha-1(VI) chain that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P13686 tartrate-resistant acid phosphatase type 5 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A tartrate-resistant acid phosphatase type 5 that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001175 common hepatic duct http://purl.obolibrary.org/obo/UBERON_0003703 extrahepatic bile duct Predominantly extrahepatic bile duct which is formed by the junction of the right and left hepatic ducts, which are predominantly intrahepatic, and, in turn, joins the cystic duct to form the common bile duct[GAID]. The common hepatic duct is the duct formed by the convergence of the right hepatic duct (which drains bile from the right functional lobe of the liver) and the left hepatic duct (which drains bile from the left functional lobe of the liver). The common hepatic duct then joins the cystic duct coming from the gallbladder to form the common bile duct[WP]. http://purl.obolibrary.org/obo/PR_P15144 aminopeptidase N (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein An aminopeptidase N that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001176 right hepatic duct http://purl.obolibrary.org/obo/UBERON_0003703 extrahepatic bile duct The duct that drains bile from the right half of the liver and joins the left hepatic duct to form the common hepatic duct. http://purl.obolibrary.org/obo/PR_P15391 B-lymphocyte antigen CD19 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A CD19 molecule that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001177 left hepatic duct http://purl.obolibrary.org/obo/UBERON_0003703 extrahepatic bile duct The duct that drains bile from the left half of the liver and joins the right hepatic duct to form the common hepatic duct. http://purl.obolibrary.org/obo/PR_P15813 antigen-presenting glycoprotein CD1d (human) http://purl.obolibrary.org/obo/PR_000036947 T-cell surface glycoprotein CD1 (human) An antigen-presenting glycoprotein CD1d that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001178 visceral peritoneum http://purl.obolibrary.org/obo/UBERON_0022350 visceral serous membrane The inner layer of peritoneum that is wrapped around organs located inside the intraperitoneal space. http://purl.obolibrary.org/obo/UBERON_0001179 peritoneal cavity http://purl.obolibrary.org/obo/UBERON_0035809 serous cavity Anatomical cavity bounded by visceral and parietal peritoneum. http://purl.obolibrary.org/obo/PR_P16070 CD44 antigen (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A CD44 molecule that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001183 inferior mesenteric artery http://purl.obolibrary.org/obo/UBERON_0035039 rectal artery Mesenteric artery that supplies the large intestine from the left colic (or splenic) flexure to the upper part of the rectum, which includes the descending colon, the sigmoid colon, and part of the rectum. Proximally, its territory of distribution overlaps (forms a watershed) with the middle colic artery, and therefore the superior mesenteric artery. The SMA and IMA anastomose via the marginal artery (artery of Drummond). The territory of distribution of the IMA is more or less equivalent to the embryonic hindgut. [WP,unvetted]. http://purl.obolibrary.org/obo/PR_P16671 platelet glycoprotein 4 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A platelet glycoprotein 4 that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001185 right renal artery http://purl.obolibrary.org/obo/UBERON_0001184 renal artery Renal artery that supplies the right kidney. http://purl.obolibrary.org/obo/PR_P17542 T-cell acute lymphocytic leukemia protein 1 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A T-cell acute lymphocytic leukemia protein 1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001186 left renal artery http://purl.obolibrary.org/obo/UBERON_0001184 renal artery Renal artery that supplies the left kidney. http://purl.obolibrary.org/obo/PR_P20138 myeloid cell surface antigen CD33 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A CD33 molecule that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001187 testicular artery http://purl.obolibrary.org/obo/UBERON_0010192 genital artery One of a pair of arteries that is a branch of the abdominal aorta that supplies blood to a male gonad. http://purl.obolibrary.org/obo/PR_P20273 B-cell receptor CD22 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A B-cell receptor CD22 that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001188 right testicular artery http://purl.obolibrary.org/obo/UBERON_0003468 ureteric segment of renal artery A testicular artery that supplies a right testicle. http://purl.obolibrary.org/obo/PR_P21728 D(1A) dopamine receptor (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A D(1A) dopamine receptor that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001189 left testicular artery http://purl.obolibrary.org/obo/UBERON_0003468 ureteric segment of renal artery A testicular artery that supplies a left testicle. http://purl.obolibrary.org/obo/PR_P21926 CD9 antigen (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A CD9 molecule that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001190 ovarian artery http://purl.obolibrary.org/obo/UBERON_0001637 artery An artery that supplies an ovary. http://purl.obolibrary.org/obo/PR_P22091 T-cell acute lymphocytic leukemia protein 1 homolog (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A T-cell acute lymphocytic leukemia protein 1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0001191 common iliac artery http://purl.obolibrary.org/obo/UBERON_0012254 abdominal aorta artery The common iliac arteries are two large arteries, about 4cm long in adults but more than a centimetre in diameter, that originate from the aortic bifurcation. The arteries run inferolaterally, along the medial border of the psoas muscles to the pelvic brim, where they bifurcate into the external iliac artery and internal iliac artery. The common iliac artery, and all of its branches, exist as paired structures (that is to say, there is one on the left side and one on the right). The distribution of the common iliac artery is basically the pelvis and lower limb on the corresponding side. Both common iliac arteries are accompanied along their course by common iliac veins. [WP,unvetted]. http://purl.obolibrary.org/obo/PR_P26842 CD27 antigen (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A CD27 molecule that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001193 hepatic artery http://purl.obolibrary.org/obo/UBERON_0001637 artery An artery that supplies the liver. http://purl.obolibrary.org/obo/PR_P27797 calreticulin (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A calreticulin that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001194 splenic artery http://purl.obolibrary.org/obo/UBERON_0001637 artery An artery that supplies the spleen. http://purl.obolibrary.org/obo/PR_P29017 T-cell surface glycoprotein CD1c (human) http://purl.obolibrary.org/obo/PR_000036947 T-cell surface glycoprotein CD1 (human) A T-cell surface glycoprotein CD1c that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001196 middle colic artery http://purl.obolibrary.org/obo/UBERON_0001637 artery The middle colic artery is a branch of the superior mesenteric artery that mostly supplies the transverse colon. It arises just below the pancreas, and, passing downward and forward between the layers of the transverse mesocolon, divides into two branches: right and left. The right branch anastomoses with the right colic artery The left branch anastomoses with the left colic artery, a branch of the inferior mesenteric artery. The arches thus formed are placed about two fingers' breadth from the transverse colon, to which they distribute branches. [WP,unvetted]. http://purl.obolibrary.org/obo/PR_P30530 tyrosine-protein kinase receptor UFO (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A tyrosine-protein kinase receptor UFO that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001197 ileocolic artery http://purl.obolibrary.org/obo/UBERON_0001637 artery The Ileocolic Artery is the lowest branch arising from the concavity of the superior mesenteric artery. It passes downward and to the right behind the peritoneum toward the right iliac fossa, where it divides into a superior and an inferior branch; the inferior anastomoses with the end of the superior mesenteric artery, the superior with the right colic artery. Supplies the cecum, ileum, and appendix. [WP,unvetted]. http://purl.obolibrary.org/obo/PR_P32248 C-C chemokine receptor type 7 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A C-C chemokine receptor type 7 that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001199 mucosa of stomach http://purl.obolibrary.org/obo/UBERON_0004786 gastrointestinal system mucosa The mucosal layer that lines the stomach. http://purl.obolibrary.org/obo/PR_P33151 cadherin-5 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A cadherin-5 that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001200 submucosa of stomach http://purl.obolibrary.org/obo/UBERON_0018257 submucosa of digestive tract The fibrous connective tissue layer beneath the stomach mucosa. http://purl.obolibrary.org/obo/PR_P33681 T-lymphocyte activation antigen CD80 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A CD80 molecule that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001201 serosa of stomach http://purl.obolibrary.org/obo/UBERON_0004782 gastrointestinal system serosa The outermost layer of the stomach wall, consisting of layers of connective tissue continuous with the peritoneum. http://purl.obolibrary.org/obo/PR_P35968 vascular endothelial growth factor receptor 2 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A vascular endothelial growth factor receptor 2 that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001202 pyloric sphincter http://purl.obolibrary.org/obo/UBERON_0011185 gastrointestinal sphincter A strong ring of smooth muscle at the end of the pyloric canal which lets food pass from the stomach to the duodenum. It receives sympathetic innervation from the celiac ganglion[WP]. http://purl.obolibrary.org/obo/PR_P36544 neuronal acetylcholine receptor subunit alpha-7 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A neuronal acetylcholine receptor subunit alpha-7 that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001203 muscularis mucosae of stomach http://purl.obolibrary.org/obo/UBERON_0006676 muscularis mucosa The thin layer of smooth muscle in the mucosal layer of the stomach that functions to agitate the surface area stomach mucosa by moving the villi back and forth. http://purl.obolibrary.org/obo/PR_P42081 T-lymphocyte activation antigen CD86 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A CD86 molecule that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001204 mucosa of small intestine http://purl.obolibrary.org/obo/UBERON_0001242 intestinal mucosa A mucosa that is part of a small intestine [Automatically generated definition]. http://purl.obolibrary.org/obo/PR_P49715 CCAAT/enhancer-binding protein alpha (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A CCAAT/enhancer-binding protein alpha that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001205 submucosa of small intestine http://purl.obolibrary.org/obo/UBERON_0009566 intestinal submucosa Submucosal tissue in the small intestines. http://purl.obolibrary.org/obo/PR_Q00653 nuclear factor NF-kappa-B p100 subunit (human) http://purl.obolibrary.org/obo/PR_000011178 nuclear factor NF-kappa-B p100 subunit A nuclear factor NF-kappa-B p100 subunit that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001206 serosa of small intestine http://purl.obolibrary.org/obo/UBERON_0001243 serosa of intestine A serous membrane that is part of a small intestine [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0001207 mucosa of large intestine http://purl.obolibrary.org/obo/UBERON_0001242 intestinal mucosa A mucosa that is part of a large intestine [Automatically generated definition]. http://purl.obolibrary.org/obo/PR_Q03692 collagen alpha-1(X) chain (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A collagen alpha-1(X) chain that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001208 submucosa of large intestine http://purl.obolibrary.org/obo/UBERON_0009566 intestinal submucosa A submucosa that is part of a large intestine [Automatically generated definition]. http://purl.obolibrary.org/obo/PR_Q13291 signaling lymphocytic activation molecule (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A SLAM family member 1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001209 serosa of large intestine http://purl.obolibrary.org/obo/UBERON_0001243 serosa of intestine A serous membrane that is part of a large intestine [Automatically generated definition]. http://purl.obolibrary.org/obo/PR_Q16602 calcitonin gene-related peptide type 1 receptor (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A calcitonin gene-related peptide type 1 receptor that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001210 muscularis mucosae of small intestine http://purl.obolibrary.org/obo/UBERON_0004239 small intestine smooth muscle A muscularis mucosa that is part of a small intestine. http://purl.obolibrary.org/obo/PR_Q86VB7 scavenger receptor cysteine-rich type 1 protein M130 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A scavenger receptor cysteine-rich type 1 protein M130 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_Q8NER1 transient receptor potential cation channel subfamily V member 1 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A transient receptor potential cation channel TRPV1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001211 Peyer's patch http://purl.obolibrary.org/obo/UBERON_0001962 gut-associated lymphoid tissue The protruding lymphoid tissue located on the mucosa of the intestine that is composed of densely packed B cell follicles. http://purl.obolibrary.org/obo/PR_Q99259 glutamate decarboxylase 1 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A glutamate decarboxylase 1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001212 duodenal gland http://purl.obolibrary.org/obo/UBERON_0011148 submucosal gland A compound tubular submucosal gland found in that portion of the duodenum which is above the hepatopancreatic sphincter (Sphincter of Oddi). The main function of these glands is to produce a mucus-rich alkaline secretion (containing bicarbonate)[WP]. http://purl.obolibrary.org/obo/PR_Q9BXN2 C-type lectin domain family 7 member A (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A C-type lectin domain family 7 member A that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001213 intestinal villus http://purl.obolibrary.org/obo/UBERON_0004923 organ component layer The tiny hair-like projections that protrude from the inside of the small intestine that contain blood vessels that capture digested nutrients that are absorbed through the intestinal wall; the villi increase the absorptive surface area of the small intestine by approximately 30-fold. http://purl.obolibrary.org/obo/PR_Q9BZS1 forkhead box protein P3 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A forkhead box protein P3 that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001215 inferior mesenteric vein http://purl.obolibrary.org/obo/UBERON_0005617 mesenteric vein A blood vessel that drains blood from the large intestine that usually terminates when reaching the splenic vein, which goes on to form the portal vein with the superior mesenteric vein (SMV). Anatomical variations include the IMV draining into the confluence of the SMV and splenic vein and the IMV draining in the SMV. The IMV lies to the right of the similarly name artery, the inferior mesenteric artery, which originates from the abdominal aorta. [WP,unvetted]. http://purl.obolibrary.org/obo/PR_Q9BZW8 natural killer cell receptor 2B4 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A natural killer cell receptor 2B4 that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001216 jejunal vein http://purl.obolibrary.org/obo/UBERON_0002017 portal vein A tributary of the superior mesenteric vein that drains the jejunum. http://purl.obolibrary.org/obo/PR_Q9UIB8 SLAM family member 5 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A SLAM family member 5 that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001217 ileal vein http://purl.obolibrary.org/obo/UBERON_0002017 portal vein The veins that drain blood from the ileum into the superior mesenteric vein. http://purl.obolibrary.org/obo/PR_O00253 agouti-related protein (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein An agouti-related protein that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001218 middle colic vein http://purl.obolibrary.org/obo/UBERON_0002017 portal vein The middle colic vein drains the transverse colon. It is a tributary of the superior mesenteric vein, and follows the path of its corresponding artery, the middle colic artery. [WP,unvetted]. http://purl.obolibrary.org/obo/PR_O09100 endothelial transcription factor GATA-2 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein An endothelial transcription factor GATA-2 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0001219 ileocolic vein http://purl.obolibrary.org/obo/UBERON_0001217 ileal vein The ileocolic vein is a vein which drains the ileum, colon, and cecum. [WP,unvetted]. http://purl.obolibrary.org/obo/PR_O14638 ectonucleotide pyrophosphatase/phosphodiesterase family member 3 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein An ectonucleotide pyrophosphatase/phosphodiesterase family member 3 that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001222 right ureter http://purl.obolibrary.org/obo/UBERON_0000056 ureter An ureter that is part of a right side of organism [Automatically generated definition]. http://purl.obolibrary.org/obo/PR_O14770 homeobox protein Meis2 (human) http://purl.obolibrary.org/obo/PR_000010317 homeobox protein Meis2 A homeobox protein Meis2 that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001223 left ureter http://purl.obolibrary.org/obo/UBERON_0000056 ureter An ureter that is part of a left side of organism [Automatically generated definition]. http://purl.obolibrary.org/obo/PR_O15353 forkhead box protein N1 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A forkhead box protein N1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001225 cortex of kidney http://purl.obolibrary.org/obo/UBERON_0001851 cortex Outer cortical portion of the kidney, between the renal capsule and the renal medulla. http://purl.obolibrary.org/obo/PR_P16297 interleukin-2 receptor subunit beta (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein An interleukin-2 receptor subunit beta that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0001228 renal papilla http://purl.obolibrary.org/obo/UBERON_0000064 organ part Tip of renal pyramid projecting into a minor calyx. http://purl.obolibrary.org/obo/PR_P16406 glutamyl aminopeptidase (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A glutamyl aminopeptidase that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0001229 renal corpuscle http://purl.obolibrary.org/obo/UBERON_0000063 organ subunit The structure containing the glomerular capsule and the glomerulus that serves as the initial blood-filtering component of a nephron. http://purl.obolibrary.org/obo/PR_P16444 dipeptidase 1 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A dipeptidase 1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001230 glomerular capsule http://purl.obolibrary.org/obo/UBERON_0000064 organ part A cup-like sac at the expanded beginning of a tubular component of a nephron that contains the glomerulus. http://purl.obolibrary.org/obo/PR_P16872 interleukin-7 receptor subunit alpha (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein An interleukin-7 receptor subunit alpha that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0001231 nephron tubule http://purl.obolibrary.org/obo/UBERON_0009773 renal tubule An epithelial tube that is part of the nephron, the functional part of the kidney. http://purl.obolibrary.org/obo/PR_P17208 POU domain, class 4, transcription factor 1 (mouse) http://purl.obolibrary.org/obo/PR_000013041 POU domain, class 4, transcription factor 1 A POU domain, class 4, transcription factor 1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P17433 transcription factor PU.1 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A transcription factor PU.1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0001233 right adrenal gland http://purl.obolibrary.org/obo/UBERON_0002369 adrenal gland An adrenal gland that is in the right side of the abdomen. http://purl.obolibrary.org/obo/PR_P17679 erythroid transcription factor (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein An erythroid transcription factor that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0001234 left adrenal gland http://purl.obolibrary.org/obo/UBERON_0002369 adrenal gland An adrenal gland that is in the left side of the abdomen. http://purl.obolibrary.org/obo/PR_P17813 endoglin (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein An endoglin that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P17947 transcription factor PU.1 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A transcription factor PU.1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001237 paraaortic body http://purl.obolibrary.org/obo/UBERON_0012279 chromaffin paraganglion A chromaffin paraganglion located at the bifurcation of the aorta or at the origin of the inferior mesenteric artery. http://purl.obolibrary.org/obo/PR_P18181 CD48 antigen (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A CD48 molecule that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0001238 lamina propria of small intestine http://purl.obolibrary.org/obo/UBERON_0004780 gastrointestinal system lamina propria Lamina propria that is part_of the small intestine. http://purl.obolibrary.org/obo/PR_P18337 L-selectin (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein An L-selectin that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0001239 muscularis mucosae of large intestine http://purl.obolibrary.org/obo/UBERON_0004220 large intestine smooth muscle A muscularis mucosa that is part of a large intestine. http://purl.obolibrary.org/obo/PR_P18828 syndecan-1 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A syndecan-1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0001240 muscularis mucosae of intestine http://purl.obolibrary.org/obo/UBERON_0006676 muscularis mucosa A muscularis mucosa that is part of a intestine. http://purl.obolibrary.org/obo/PR_P19070 complement receptor type 2 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A complement receptor type 2 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0001241 crypt of Lieberkuhn of small intestine http://purl.obolibrary.org/obo/UBERON_0001983 crypt of Lieberkuhn The tubular intestinal glands found in the mucosal membranes of the small intestine. http://purl.obolibrary.org/obo/PR_P19246 neurofilament heavy polypeptide (mouse) http://purl.obolibrary.org/obo/PR_000011118 neurofilament heavy polypeptide A neurofilament heavy polypeptide that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0001242 intestinal mucosa http://purl.obolibrary.org/obo/UBERON_0004786 gastrointestinal system mucosa Mucosal layer that lines the intestine. http://purl.obolibrary.org/obo/PR_P19437 B-lymphocyte antigen CD20 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A membrane-spanning 4-domains subfamily A member 1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0001243 serosa of intestine http://purl.obolibrary.org/obo/UBERON_0004782 gastrointestinal system serosa A serous membrane that is part of a wall of intestine [Automatically generated definition]. http://purl.obolibrary.org/obo/PR_P19785 estrogen receptor (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein An estrogen receptor that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0001246 interlobular bile duct http://purl.obolibrary.org/obo/UBERON_0003704 intrahepatic bile duct The canals that carry bile in the liver between the intralobular ducts and the biliary ductules; interlobular bile ducts are part of the interlobular portal triad. http://purl.obolibrary.org/obo/PR_P20023 complement receptor type 2 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A complement receptor type 2 that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001247 falciform ligament http://purl.obolibrary.org/obo/UBERON_0013139 ligament of liver A ligament that attaches the liver to the anterior body wall. It is a broad and thin antero-posterior peritoneal fold, falciform in shape, its base being directed downward and backward and its apex upward and backward. It is a remnant of the ventral mesentery of the fetus. It is situated in an antero-posterior plane but lies obliquely, so that one surface faces forward and is in contact with the peritoneum behind the right rectus and the diaphragm, while the other is directed backward and is in contact with the left lobe of the liver. It is attached by its left margin to the under surface of the diaphragm and the posterior surface of the sheath of the right Rectus as low down as the umbilicus; by its right margin it extends from the notch on the anterior margin of the liver, as far back as the posterior surface. It is composed of two layers of peritoneum closely united together. Its base or free edge contains between its layers the round ligament and the paraumbilical veins[WP]. http://purl.obolibrary.org/obo/PR_P20152 vimentin (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A vimentin that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0001249 spleen lymphoid follicle http://purl.obolibrary.org/obo/UBERON_0000444 lymphoid follicle The area of the white pulp where the affinity maturation of B cells and the generation of memory B cells and plasma cells occur. http://purl.obolibrary.org/obo/PR_P20366 protachykinin-1 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A protachykinin-1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001250 red pulp of spleen http://purl.obolibrary.org/obo/UBERON_1000023 spleen pulp The parenchymatous tissue network of the spleen that consists of loose plates or cords (sinuses) infiltrated with red blood cells where most of the blood filtration occurs and degenerate erythrocytes are removed from the circulation. http://purl.obolibrary.org/obo/PR_P20472 parvalbumin alpha (human) http://purl.obolibrary.org/obo/PR_000013502 parvalbumin alpha A parvalbumin alpha that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001251 marginal zone of spleen http://purl.obolibrary.org/obo/UBERON_0000064 organ part The zone between the red and white pulp of the spleen containing numerous macrophages and lymphocytes, and a rich plexus of sinusoids supplied by white pulp arterioles carrying blood-borne antigens. http://purl.obolibrary.org/obo/PR_P20489 high affinity immunoglobulin epsilon receptor subunit alpha (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A high affinity immunoglobulin epsilon receptor subunit alpha that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0001252 adventitia of ureter http://purl.obolibrary.org/obo/UBERON_0005742 adventitia An adventitia that is part of a ureter. http://purl.obolibrary.org/obo/PR_P20693 low affinity immunoglobulin epsilon Fc receptor (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A low affinity immunoglobulin epsilon Fc receptor that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0001253 lamina propria of ureter http://purl.obolibrary.org/obo/UBERON_0000030 lamina propria A lamina propria that is part of a ureter [Automatically generated definition]. http://purl.obolibrary.org/obo/PR_P20718 granzyme H (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A granzyme H that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001254 urothelium of ureter http://purl.obolibrary.org/obo/UBERON_0000365 urothelium The luminal epithelium of the tube that conducts the urine from the renal pelvis to the bladder[MP]. http://purl.obolibrary.org/obo/PR_P20937 T-cell surface glycoprotein YE1/48 (mouse) http://purl.obolibrary.org/obo/PR_000009616 T-cell surface glycoprotein YE1/48 A T-cell surface glycoprotein YE1/48 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0001256 wall of urinary bladder http://purl.obolibrary.org/obo/UBERON_0000060 anatomical wall An anatomical wall that lines the insider of a urinary bladder. http://purl.obolibrary.org/obo/PR_P21183 interleukin-5 receptor subunit alpha (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein An interleukin-5 receptor subunit alpha that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0001259 mucosa of urinary bladder http://purl.obolibrary.org/obo/UBERON_0000344 mucosa The mucous membrane lining the urinary bladder. http://purl.obolibrary.org/obo/PR_P21462 fMet-Leu-Phe receptor (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein An fMet-Leu-Phe receptor that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001260 serosa of urinary bladder http://purl.obolibrary.org/obo/UBERON_0000042 serous membrane A serous membrane that is part of a urinary bladder [Automatically generated definition]. http://purl.obolibrary.org/obo/PR_P21757 macrophage scavenger receptor types I and II (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A macrophage scavenger receptor types I and II that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001261 lamina propria of urinary bladder http://purl.obolibrary.org/obo/UBERON_0000030 lamina propria A lamina propria that is part of a urinary bladder [Automatically generated definition]. http://purl.obolibrary.org/obo/PR_P21784 V(D)J recombination-activating protein 2 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A V(D)J recombination-activating protein 2 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0001262 wall of intestine http://purl.obolibrary.org/obo/UBERON_0000328 gut wall An anatomical wall that is part of a intestine [Automatically generated definition]. http://purl.obolibrary.org/obo/PR_P22005 proenkephalin-A (mouse) http://purl.obolibrary.org/obo/PR_000012544 proenkephalin-A A proenkephalin-A that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0001263 pancreatic acinus http://purl.obolibrary.org/obo/UBERON_0013232 serous acinus The secretory units of the exocrine pancreas, where fluid containing digestive enzymes is produced; consists of a group of secretory cells surrounding a luminal space that connects to the pancreatic duct. http://purl.obolibrary.org/obo/PR_P22083 alpha-(1,3)-fucosyltransferase 4 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein An alpha-(1,3)-fucosyltransferase 4 that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001265 trabecula of spleen http://purl.obolibrary.org/obo/UBERON_0000440 trabecula A trabecula that is part of a spleen. http://purl.obolibrary.org/obo/PR_P22387 endothelin-1 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein An endothelin-1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0001266 splenic cord http://purl.obolibrary.org/obo/UBERON_0000064 organ part A structure found in the red pulp of the spleen between the sinusoids, consisting of fibrils and connective tissue cells with a large population of monocytes and macrophages. These cords contain half of the human body's monocytes as a reserve so that after tissue injury these monocytes can move in and aid locally sourced monocytes in wound healing. Erythrocytes pass through the cords of Billroth before entering the sinusoids. The passage into the sinusoids may be seen as a bottleneck, where erythrocytes need to be flexible in order to pass through. In disorders of erythrocyte shape and/or flexibility, such as hereditary spherocytosis, erythrocytes fail to pass through and get phagocytosed, causing extravascular hemolysis. http://purl.obolibrary.org/obo/PR_P22466 galanin peptides (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A galanin that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001268 peritoneal fluid http://purl.obolibrary.org/obo/UBERON_0036217 coelomic fluid Transudate contained in the peritoneal cavity. http://purl.obolibrary.org/obo/PR_P22646 T-cell surface glycoprotein CD3 epsilon chain (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A CD3 epsilon that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0001271 pelvic girdle region http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure The organism subdivision that includes the pelvic girdle skeleton and associated soft tissue. Note that this includes both the skeletal elements and associated tissues (integument, muscle, etc). Examples: There are only two instances in an organism, right and left pelvic girdle regions. http://purl.obolibrary.org/obo/PR_P22676 calretinin (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A calretinin that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P22858 parathyroid hormone-related protein (mouse) http://purl.obolibrary.org/obo/PR_000013433 parathyroid hormone-related protein A parathyroid hormone-related protein that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0001272 innominate bone http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure A fused bone consisting of the ilium, ischium and pubis. Together with the sacrum and coccyx, it comprises the pelvis. [WP,modified]. http://purl.obolibrary.org/obo/PR_P23769 endothelial transcription factor GATA-2 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein An endothelial transcription factor GATA-2 that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001273 ilium http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure Paired endochondral bone that is the dorsal-most of the pelvic bones, offering attachment areas for gluteal muscles on its main surface [PHENOSCAPE:ad]. http://purl.obolibrary.org/obo/PR_P23772 trans-acting T-cell-specific transcription factor GATA-3 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A trans-acting T-cell-specific transcription factor GATA-3 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0001274 ischium http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure Endochondral bone that is paired, forming the posterior part of the pelvis, articulating with the pubis and ilium. http://purl.obolibrary.org/obo/PR_P24529 tyrosine 3-monooxygenase (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A tyrosine 3-monooxygenase that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0001276 epithelium of stomach http://purl.obolibrary.org/obo/UBERON_0015833 foregut epithelium The epithelial layer of the stomach . http://purl.obolibrary.org/obo/PR_P55075 fibroblast growth factor 8 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A fibroblast growth factor 8 that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001277 intestinal epithelium http://purl.obolibrary.org/obo/UBERON_0004808 gastrointestinal system epithelium Epithelial layer that lines the intestine. http://purl.obolibrary.org/obo/PR_P55097 cathepsin K (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A cathepsin K that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0001278 epithelium of large intestine http://purl.obolibrary.org/obo/UBERON_0001277 intestinal epithelium An epithelium that is part of a large intestine [Automatically generated definition]. http://purl.obolibrary.org/obo/PR_P55099 tachykinin-3 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A tachykinin-3 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0001279 portal triad http://purl.obolibrary.org/obo/UBERON_0034921 multi organ part structure A multi-organ-part structure that consists of three vessels of the portal lobule including the bile duct, a terminal branch of the hepatic artery and portal vein, and may also include a lymphatic vessel. http://purl.obolibrary.org/obo/PR_P55284 cadherin-5 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A cadherin-5 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0001280 liver parenchyma http://purl.obolibrary.org/obo/UBERON_0004119 endoderm-derived structure The functional units of the liver including the lobules. http://purl.obolibrary.org/obo/PR_P55772 ectonucleoside triphosphate diphosphohydrolase 1 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein An ectonucleoside triphosphate diphosphohydrolase 1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0001281 hepatic sinusoid http://purl.obolibrary.org/obo/UBERON_0015796 liver blood vessel Wide thin-walled blood vessels in the liver. In mammals they have neither veinous or arterial markers. http://purl.obolibrary.org/obo/PR_P55895 V(D)J recombination-activating protein 2 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A V(D)J recombination-activating protein 2 that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001282 intralobular bile duct http://purl.obolibrary.org/obo/UBERON_0014716 interlobular duct The tubules located between the bile canaliculi and interlobular bile ducts near the outer edge of a classic liver lobule. http://purl.obolibrary.org/obo/PR_P56373 P2X purinoceptor 3 (human) http://purl.obolibrary.org/obo/PR_000012190 P2X purinoceptor 3 A P2X purinoceptor 3 that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001285 nephron http://purl.obolibrary.org/obo/UBERON_0000064 organ part The basic functional unit of the kidney. its chief function is to regulate the concentration of water and soluble substances like sodium salts by filtering the blood, reabsorbing what is needed and excreting the rest as urine. A nephron eliminates wastes from the body, regulates blood volume and blood pressure, controls levels of electrolytes and metabolites, and regulates blood pH. Its functions are vital to life and are regulated by the endocrine system by hormones such as antidiuretic hormone, aldosterone, and parathyroid hormone.[WP]. http://purl.obolibrary.org/obo/PR_P56473 agouti-related protein (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein An agouti-related protein that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P56528 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein An ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0001286 Bowman's space http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space A narrow chalice-shaped cavity between the glomerular and capsular epithelium of the glomerular capsule of the kidney[TFD]. Between the visceral and parietal layers, into which the filtrate enters after passing through the podocytes' filtration slits[WP]. luminal region between the glomerular capsule visceral and parietal layers, into which filtrate enters after passing through the filtration barrier from the glomerular capillaries[MP]. http://purl.obolibrary.org/obo/PR_P57774 pro-neuropeptide Y (mouse) http://purl.obolibrary.org/obo/PR_000011387 neuropeptide Y A neuropeptide Y that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0001287 proximal convoluted tubule http://purl.obolibrary.org/obo/UBERON_0012275 meso-epithelium The proximal convoluted tubule is the most proximal portion of the proximal tubule and extends from the glomerular capsule to the proximal straight tubule. http://purl.obolibrary.org/obo/PR_P58462 forkhead box protein P1 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A forkhead box protein P1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0001288 loop of Henle http://purl.obolibrary.org/obo/UBERON_0007685 region of nephron tubule The section of the renal tubule in the kidney medulla with a hairpin bend; consists of a descending limb and an ascending limb, and is situated between the proximal convoluted tubule to the distal convoluted tubule; it functions to reabsorb water and ions from the urine. http://purl.obolibrary.org/obo/PR_P60041 somatostatin (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A somatostatin that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0001289 descending limb of loop of Henle http://purl.obolibrary.org/obo/UBERON_0007685 region of nephron tubule The portion of the renal tubule that constitutes the proximal part of the loop of Henle, has low permeability to ions and urea, and is highly permeable to water; it consists of an initial short thick segment lined by low simple cuboidal epithelium and a long thin segment lined by simple squamous epithelium; however, this distinction is not as important physiologically as in the ascending limb, so often the two are treated as one structure. http://purl.obolibrary.org/obo/PR_P61073 C-X-C chemokine receptor type 4 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A C-X-C chemokine receptor type 4 that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001290 proximal straight tubule http://purl.obolibrary.org/obo/UBERON_0009035 renal straight tubule The proximal straight tubule is the part of the descending limb that extends from the proximal convoluted tubule to the descending thin tubule. http://purl.obolibrary.org/obo/PR_P61148 fibroblast growth factor 1 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A fibroblast growth factor 1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0001291 thick ascending limb of loop of Henle http://purl.obolibrary.org/obo/UBERON_0009035 renal straight tubule The distal sub-portion of the ascending loop of Henle which is lined by simple cuboidal epithelium and enters the renal cortex to empty a hypotonic filtrate into the distal convoluted tubule. http://purl.obolibrary.org/obo/PR_P61168 D(2) dopamine receptor (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A D(2) dopamine receptor that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0001292 distal convoluted tubule http://purl.obolibrary.org/obo/UBERON_0012275 meso-epithelium The first segment of the nephron lying just downstream from the loop of Henle, immediately after the macula densa. http://purl.obolibrary.org/obo/PR_P61278 somatostatin (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A somatostatin that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001293 outer medulla of kidney http://purl.obolibrary.org/obo/UBERON_0000064 organ part The renal outer medulla is the region of the kidney that lies between the renal cortex and the renal inner medulla[GO]. http://purl.obolibrary.org/obo/PR_P62736 actin, aortic smooth muscle (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein An actin, aortic smooth muscle that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001294 inner medulla of kidney http://purl.obolibrary.org/obo/UBERON_0000064 organ part Innermost region of the mammalian kidney. http://purl.obolibrary.org/obo/PR_P62737 actin, aortic smooth muscle (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein An actin, aortic smooth muscle that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0001297 serosa of uterus http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure Outer serosa layer of the uterus. http://purl.obolibrary.org/obo/PR_P63015 paired box protein Pax-6 (mouse) http://purl.obolibrary.org/obo/PR_000012318 paired box protein Pax-6 A paired box protein Pax-6 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0001302 right fallopian tube http://purl.obolibrary.org/obo/UBERON_0003889 fallopian tube A fallopian tube that is part of a right side of organism [Automatically generated definition]. http://purl.obolibrary.org/obo/PR_Q12918 killer cell lectin-like receptor subfamily B member 1 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A killer cell lectin-like receptor subfamily B member 1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001303 left fallopian tube http://purl.obolibrary.org/obo/UBERON_0003889 fallopian tube A fallopian tube that is part of a left side of organism [Automatically generated definition]. http://purl.obolibrary.org/obo/PR_Q13241 natural killer cells antigen CD94 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A killer cell lectin-like receptor subfamily D member 1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001304 germinal epithelium of ovary http://purl.obolibrary.org/obo/UBERON_0004911 epithelium of female gonad Layer of simple cuboidal cells covering surface of ovary[WP]. http://purl.obolibrary.org/obo/PR_Q13445 transmembrane emp24 domain-containing protein 1 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A transmembrane emp24 domain-containing protein 1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001305 ovarian follicle http://purl.obolibrary.org/obo/UBERON_8450001 egg follicle A spherical aggregation of cells in the ovary that contains a single oocyte[WP,modified]. http://purl.obolibrary.org/obo/PR_Q14246 adhesion G protein-coupled receptor E1 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein An adhesion G protein-coupled receptor E1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001307 capsule of ovary http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure A capsule that surrounds a female gonad. http://purl.obolibrary.org/obo/PR_Q14515 SPARC-like protein 1 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A SPARC-like protein 1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_Q15063 periostin (human) http://purl.obolibrary.org/obo/PR_000013031 periostin A periostin that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_Q15465 sonic hedgehog protein (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A sonic hedgehog protein that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001308 external iliac artery http://purl.obolibrary.org/obo/UBERON_0005609 iliac artery The external iliac artery is a large artery in the pelvic region that carries blood to the lower limb. The external iliac artery is a paired artery, meaning there is one on each side of the body: a right external iliac artery and left external iliac artery. The external iliac artery is accompanied by the external iliac vein, which is located posterior to the artery. [WP,unvetted]. http://purl.obolibrary.org/obo/PR_Q15726 metastasis-suppressor KiSS-1 (human) http://purl.obolibrary.org/obo/PR_000009344 metastasis-suppressor KiSS-1 A metastasis-suppressor KiSS-1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_Q15744 CCAAT/enhancer-binding protein epsilon (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A CCAAT/enhancer-binding protein epsilon that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001309 internal iliac artery http://purl.obolibrary.org/obo/UBERON_0005609 iliac artery The internal iliac artery (formerly known as the hypogastric artery) is the main artery of the pelvis. [WP,unvetted]. http://purl.obolibrary.org/obo/PR_Q15858 sodium channel protein type 9 subunit alpha (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A sodium channel protein type 9 subunit alpha that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_Q16572 vesicular acetylcholine transporter (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A vesicular acetylcholine transporter that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001310 umbilical artery http://purl.obolibrary.org/obo/UBERON_0010260 umbilical blood vessel The umbilical artery is a paired artery (with one for each half of the body) that is found in the abdominal and pelvic regions. In the fetus, it extends into the umbilical cord. [WP,unvetted]. http://purl.obolibrary.org/obo/PR_Q18PI6 SLAM family member 5 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A SLAM family member 5 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0001311 inferior vesical artery http://purl.obolibrary.org/obo/UBERON_0009027 vesical artery An artery that supplies blood to the lower urinary bladder. http://purl.obolibrary.org/obo/PR_Q62205 sodium channel protein type 9 subunit alpha (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A sodium channel protein type 9 subunit alpha that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0001312 superior vesical artery http://purl.obolibrary.org/obo/UBERON_0009027 vesical artery An artery that supplies blood to the upper urinary bladder. http://purl.obolibrary.org/obo/PR_Q62230 sialoadhesin (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A sialoadhesin that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0001316 external iliac vein http://purl.obolibrary.org/obo/UBERON_0005610 iliac vein A large vein that connects the femoral vein to the common iliac vein. Their origin is at the inferior margin of the inguinal ligaments and they terminate when they join the internal iliac veins (to form the common iliac veins). Both external iliac veins are accompanied along their course by external iliac arteries. [WP,modified]. http://purl.obolibrary.org/obo/PR_Q62233 homeobox protein SIX3 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A homeobox protein SIX3 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0001317 internal iliac vein http://purl.obolibrary.org/obo/UBERON_0005610 iliac vein A vein that begins near the upper part of the greater sciatic foramen, passes upward behind and slightly medial to the hypogastric artery and, at the brim of the pelvis, joins with the external iliac to form the common iliac vein. [WP,unvetted]. http://purl.obolibrary.org/obo/PR_Q62351 transferrin receptor protein 1 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A transferrin receptor protein 1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0001319 vaginal vein http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure One the veins that drains the vaginal venous plexus, into the hypogastric veins. [WP,modified]. http://purl.obolibrary.org/obo/PR_Q62469 integrin alpha-2 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein An integrin alpha-2 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0001325 muscle of pelvis http://purl.obolibrary.org/obo/UBERON_0005179 pelvic region element Muscle (organ) which is a part of the pelvis. Examples: levator ani,. http://purl.obolibrary.org/obo/PR_Q63961 endoglin (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein An endoglin that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0001328 lobe of prostate http://purl.obolibrary.org/obo/UBERON_0009912 anatomical lobe A portion of a prostate that forms a lobe. http://purl.obolibrary.org/obo/PR_Q63994 myeloid cell surface antigen CD33 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A CD33 molecule that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0001330 pampiniform plexus http://purl.obolibrary.org/obo/UBERON_0001593 venous plexus The pampiniform plexus is a network of many small veins found in the male spermatic cord. It is formed by the union of multiple spermatic veins from the back of the testis and tributaries from the epididymis. The veins of the plexus ascend along the cord in front of the ductus deferens. Below the subcutaneous inguinal ring they unite to form three or four veins, which pass along the inguinal canal, and, entering the abdomen through the abdominal inguinal ring, coalesce to form two veins. These again unite to form a single vein, the testicular vein, which opens on the right side into the inferior vena cava, at an acute angle, and on the left side into the left renal vein, at a right angle. The pampinoform plexus forms the chief mass of the cord. In addition to its function in venous return from the testes, the pampiniform plexus also plays a role in the temperature regulation of the testes. It acts as a heat exchanger, cooling blood in adjacent arteries. An abnormal enlargement of the pampiniform plexus is a medical condition called varicocele. [WP,unvetted]. http://purl.obolibrary.org/obo/PR_Q64237 dopamine beta-hydroxylase (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A dopamine beta-hydroxylase that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0001331 skin of penis http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure A zone of skin that is part of a penis [Automatically generated definition]. http://purl.obolibrary.org/obo/PR_Q64314 hematopoietic progenitor cell antigen CD34 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A CD34 molecule that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0001332 prepuce of penis http://purl.obolibrary.org/obo/UBERON_0011374 prepuce A retractable double-layered fold of skin and mucous membrane that covers the glans penis and protects the urinary meatus when the penis is not erect. http://purl.obolibrary.org/obo/PR_Q64329 killer cell lectin-like receptor 3 (mouse) http://purl.obolibrary.org/obo/PR_000009618 killer cell lectin-like receptor 3 A killer cell lectin-like receptor 3 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0001333 male urethra http://purl.obolibrary.org/obo/UBERON_0000057 urethra A urethra that is part of a male reproductive system. http://purl.obolibrary.org/obo/PR_Q67BJ4 lactosylceramide 4-alpha-galactosyltransferase (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A lactosylceramide 4-alpha-galactosyltransferase that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0001334 female urethra http://purl.obolibrary.org/obo/UBERON_0000057 urethra A urethra that is part of a female reproductive system. http://purl.obolibrary.org/obo/PR_Q8BJI4 POU domain, class 6, transcription factor 2 (mouse) http://purl.obolibrary.org/obo/PR_000013047 POU domain, class 6, transcription factor 2 A POU domain, class 6, transcription factor 2 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0001335 prostatic urethra http://purl.obolibrary.org/obo/UBERON_0013522 subdivision of tube The widest and most dilatable part of the male urethra canal which runs almost vertically through the prostate from its base to its apex, lying nearer its anterior than its posterior surface; this portion of the urethral canal is spindle-shaped, being wider in the middle than at either extremity, and narrowest below, where it joins the membranous portion; it is lined by transitional epithelium and contains in its posterior wall, or floor, the orifices of the prostatic utricle, ejaculatory ducts, and prostatic ducts, collectively known as the seminal colliculus (aka verumontanum). http://purl.obolibrary.org/obo/PR_Q8BLE7 vesicular glutamate transporter 2 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A vesicular glutamate transporter 2 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0001338 urethral gland http://purl.obolibrary.org/obo/UBERON_0000414 mucous gland Any of the numerous small mucous-secreting glands located in the wall of the male or female urethra that help protect the epithelium from the corrosive urine. http://purl.obolibrary.org/obo/PR_Q8C567 natural cytotoxicity triggering receptor 1 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A natural cytotoxicity triggering receptor 1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0001343 seminiferous tubule of testis http://purl.obolibrary.org/obo/UBERON_0005904 duct of male reproductive system The tubules in the testes where spermatogenesis occurs. http://purl.obolibrary.org/obo/PR_Q8CD54 piezo-type mechanosensitive ion channel component 2 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A piezo-type mechanosensitive ion channel component 2 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0001344 epithelium of vagina http://purl.obolibrary.org/obo/UBERON_0004804 oviduct epithelium The epithelial layer of the vagina. http://purl.obolibrary.org/obo/PR_Q99JA0-1 calcitonin gene-related peptide 1 (mouse) http://purl.obolibrary.org/obo/PR_000027226 calcitonin gene-related peptide 1 A calcitonin gene-related peptide 1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q99JB6 forkhead box protein P3 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A forkhead box protein P3 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0001347 white adipose tissue http://purl.obolibrary.org/obo/UBERON_0001013 adipose tissue Connective tissue consisting of fat-storing cells and arranged in lobular groups or along minor blood vessels[MP,modified]. http://purl.obolibrary.org/obo/PR_Q99NH8 triggering receptor expressed on myeloid cells 2 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A triggering receptor expressed on myeloid cells 2 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0001348 brown adipose tissue http://purl.obolibrary.org/obo/UBERON_0001013 adipose tissue A thermogenic form of adipose tissue that is composed of brown adipocytes[MP,modified]. http://purl.obolibrary.org/obo/PR_Q99PV8 B-cell lymphoma/leukemia 11B (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A B-cell lymphoma/leukemia 11B that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0001351 lacrimal sac http://purl.obolibrary.org/obo/UBERON_0034944 zone of organ The upper dilated end of the nasolacrimal duct that is lodged in a deep groove formed by the lacrimal bone and frontal process of the maxilla; it connects the lacrimal canaliculi, which drain tears from the eye's surface, and the nasolacrimal duct, which conveys this fluid into the nasal cavity; like the nasolacrimal duct, the sac is lined by stratified columnar epithelium with mucus-secreting goblet cells, and is surrounded by connective tissue. http://purl.obolibrary.org/obo/PR_Q9H334 forkhead box protein P1 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A forkhead box protein P1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001352 external acoustic meatus http://purl.obolibrary.org/obo/UBERON_0004111 anatomical conduit A tube running from the outer ear to the middle ear. The human ear canal extends from the pinna to the eardrum and is about 26 mm in length and 7 mm in diameter. http://purl.obolibrary.org/obo/PR_Q9H5I5 piezo-type mechanosensitive ion channel component 2 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A piezo-type mechanosensitive ion channel component 2 that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001353 anal region http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision The anus and surrounding regions. Encompasses both internal and external regions, where present. http://purl.obolibrary.org/obo/PR_Q9H9P2 chondrolectin (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A chondrolectin that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001355 deep femoral artery http://purl.obolibrary.org/obo/UBERON_0001637 artery The profunda femoris artery (also known as the deep femoral artery, or the deep artery of the thigh) is a branch of the femoral artery that, as its name suggests, travels more deeply (posteriorly) than the rest of the femoral artery. [WP,unvetted]. http://purl.obolibrary.org/obo/PR_Q9HBX9 relaxin receptor 1 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A relaxin receptor 1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001356 medial circumflex femoral artery http://purl.obolibrary.org/obo/UBERON_0001637 artery The medial circumflex femoral artery (internal circumflex artery, medial femoral circumflex artery) is an artery in the upper thigh that helps supply blood to the neck of the femur. [WP,unvetted]. http://purl.obolibrary.org/obo/PR_Q9JIP3 interleukin-17 receptor B (mouse) http://purl.obolibrary.org/obo/PR_000008982 interleukin-17 receptor B An interleukin-17 receptor B that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0001359 cerebrospinal fluid http://purl.obolibrary.org/obo/UBERON_0007779 transudate A clear, colorless, bodily fluid, that occupies the subarachnoid space and the ventricular system around and inside the brain and spinal cord. http://purl.obolibrary.org/obo/PR_Q9JKD8 T-box transcription factor TBX21 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A T-box transcription factor TBX21 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0001363 great saphenous vein http://purl.obolibrary.org/obo/UBERON_0007318 saphenous vein The great saphenous vein (GSV), also greater saphenous vein, is the large (subcutaneous) superficial vein of the leg and thigh. The terms 'safaina' (Greek) and 'el safin' (Arabic) have both been claimed as the origin for the word 'saphenous'. [WP,unvetted]. http://purl.obolibrary.org/obo/PR_Q9JKF4 C-type lectin domain family 6 member A (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A C-type lectin domain family 6 member A that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0001366 parietal peritoneum http://purl.obolibrary.org/obo/UBERON_0022351 parietal serous membrane The outer layer of peritoneum that is attached to the abdominal and pelvic walls. http://purl.obolibrary.org/obo/PR_Q9UBR4 LIM/homeobox protein Lhx3 (human) http://purl.obolibrary.org/obo/PR_000009793 LIM/homeobox protein Lhx3 A LIM/homeobox protein Lhx3 that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001383 muscle of leg http://purl.obolibrary.org/obo/UBERON_0003663 hindlimb muscle A muscle that is part of the region of the hindlimb between the pelvis and ankle. http://purl.obolibrary.org/obo/PR_Q9UEW3 macrophage receptor MARCO (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A macrophage receptor MARCO that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001384 primary motor cortex http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain The part of the cerebral cortex that receives projections from the motor thalamus and which projects to motor neurons in the brainstem and spinal cord. The motor cortex corresponds to Brodmann's area 4 (MM). The primary motor cortex, or M1, is located on the precentral gyrus and on the anterior paracentral lobule on the medial surface of the brain. Of the three motor cortex areas, stimulation of the primary motor cortex requires the least amount of electrical current to elicit a movement. http://neuroscience.uth.tmc.edu/s3/chapter03.html. http://purl.obolibrary.org/obo/PR_Q9UHF0 tachykinin-3 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A tachykinin-3 that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001394 axillary artery http://purl.obolibrary.org/obo/UBERON_0001637 artery Artery that supplies the axilla. http://purl.obolibrary.org/obo/PR_Q9UHM6 melanopsin (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A melanopsin that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001397 subscapular artery http://purl.obolibrary.org/obo/UBERON_0001637 artery The subscapular artery, the largest branch of the axillary artery, arises at the lower border of the Subscapularis, which it follows to the inferior angle of the scapula, where it anastomoses with the lateral thoracic and intercostal arteries and with the descending branch of the transverse cervical, and ends in the neighboring muscles. About 4 cm. from its origin it gives off two branches, first the scapular circumflex artery and then the thoracodorsal artery. [WP,unvetted]. http://purl.obolibrary.org/obo/PR_Q9UI33 sodium channel protein type 11 subunit alpha (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A sodium channel protein type 11 subunit alpha that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001415 skin of pelvis http://purl.obolibrary.org/obo/UBERON_0003836 abdominal segment skin A zone of skin that is part of a pelvis [Automatically generated definition]. http://purl.obolibrary.org/obo/PR_Q9UIK5 tomoregulin-2 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A tomoregulin-2 that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001416 skin of abdomen http://purl.obolibrary.org/obo/UBERON_0003836 abdominal segment skin A zone of skin that is part of an abdomen [Automatically generated definition]. http://purl.obolibrary.org/obo/PR_Q9UJ71 C-type lectin domain family 4 member K (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A C-type lectin domain family 4 member K that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001417 skin of neck http://purl.obolibrary.org/obo/UBERON_0000014 zone of skin A zone of skin that is part of a neck [Automatically generated definition]. http://purl.obolibrary.org/obo/PR_Q9UJQ1 lysosome-associated membrane glycoprotein 5 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A lysosome-associated membrane glycoprotein 5 that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001418 skin of thorax http://purl.obolibrary.org/obo/UBERON_0001085 skin of trunk A zone of skin that is part of a thorax [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0001419 skin of limb http://purl.obolibrary.org/obo/UBERON_0000014 zone of skin A zone of skin that is part of a limb [Automatically generated definition]. http://purl.obolibrary.org/obo/PR_Q9UL17 T-box transcription factor TBX21 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A T-box transcription factor TBX21 that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001421 pectoral girdle region http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure An organism subdivision that includes the pectoral girdle skeleton and associated soft tissue. Note that this includes both the skeletal elements and associated tissues (integument, muscle, etc). Examples: There are only two instances in an organism, right and left pectoral girdle regions. http://purl.obolibrary.org/obo/PR_Q9UPM6 LIM/homeobox protein Lhx6 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A LIM/homeobox protein Lhx6 that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0001422 facial lymphatic vessel http://purl.obolibrary.org/obo/UBERON_0001473 lymphatic vessel A lymphatic vessel that is part of a face [Automatically generated definition]. http://purl.obolibrary.org/obo/CL_0008024 pancreatic endocrine cell http://purl.obolibrary.org/obo/CL_0000164 enteroendocrine cell An endocrine cell that is part of the pancreas. http://purl.obolibrary.org/obo/UBERON_0001434 skeletal system http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision Anatomical system that is a multi-element, multi-tissue anatomical cluster that consists of the skeleton and the articular system. http://purl.obolibrary.org/obo/CL_0011115 precursor cell http://purl.obolibrary.org/obo/CL_0000000 cell A cell that, by division or terminal differentiation, can give rise to other cell types. http://purl.obolibrary.org/obo/UBERON_0001435 carpal bone http://purl.obolibrary.org/obo/UBERON_0015049 carpus endochondral element A bone that is part of the carpal skeleton. Examples: scaphoid, lunate, capitate[cjm]. http://purl.obolibrary.org/obo/GO_0140029 exocytic process http://purl.obolibrary.org/obo/GO_0009987 cellular process The cellular processes that contribute to exocytosis. http://purl.obolibrary.org/obo/UBERON_0001436 phalanx of manus http://purl.obolibrary.org/obo/UBERON_0015024 manual digit phalanx endochondral element A phalanx that is part of a forelimb autopod[Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0140039 cell-cell adhesion in response to extracellular stimulus http://purl.obolibrary.org/obo/GO_0098609 cell-cell adhesion The attachment of one cell to another cell via adhesion molecules as a result of an extracellular stimulus. http://purl.obolibrary.org/obo/UBERON_0001437 epiphysis http://purl.obolibrary.org/obo/UBERON_0005055 zone of long bone The head of a long bone that articulates with a neighboring skeletal element and is separated from the shaft by the epiphyseal plate until bone growth stops. At that time, the plate disappears and the head and shaft are united[MESH,modified]. http://purl.obolibrary.org/obo/GO_0099161 regulation of presynaptic dense core granule exocytosis http://purl.obolibrary.org/obo/GO_0099171 presynaptic modulation of chemical synaptic transmission Any process that modulates the frequency, rate or extent of presynaptic dense core granule exocytosis. http://purl.obolibrary.org/obo/UBERON_0001438 metaphysis http://purl.obolibrary.org/obo/UBERON_0005055 zone of long bone Zone of long bone that is between the epiphysis and diaphysis. Subdivision of diaphysis which forms the proximal or distal end of diaphysis next to the epiphysis; together with diaphysis proper, it constitutes the diaphysis. Examples: proximal metaphysis of humerus, distal metaphysis of femur.[FMA]. http://purl.obolibrary.org/obo/GO_0099170 postsynaptic modulation of chemical synaptic transmission http://purl.obolibrary.org/obo/GO_0050804 modulation of chemical synaptic transmission Any process, acting in the postsynapse that results in modulation of chemical synaptic transmission. http://purl.obolibrary.org/obo/UBERON_0001439 compact bone tissue http://purl.obolibrary.org/obo/UBERON_0002481 bone tissue The outer layers of solid, hard bone that covers spongy bone; consists of parallel osteons containing mineral deposits and interstitial lamellae. http://purl.obolibrary.org/obo/GO_0099171 presynaptic modulation of chemical synaptic transmission http://purl.obolibrary.org/obo/GO_0050804 modulation of chemical synaptic transmission Any process, acting in the presynapse that results in modulation of chemical synaptic transmission. http://purl.obolibrary.org/obo/UBERON_0001440 forelimb skeleton http://purl.obolibrary.org/obo/UBERON_0007272 pectoral appendage skeleton The collection of all skeletal elements in a free forelimb region. Excludes the pectoral girdle. http://purl.obolibrary.org/obo/GO_0099172 presynapse organization http://purl.obolibrary.org/obo/GO_0016043 cellular component organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a presynapse. http://purl.obolibrary.org/obo/UBERON_0001441 hindlimb skeleton http://purl.obolibrary.org/obo/UBERON_0007273 pelvic appendage skeleton Subdivision of skeleton consisting of all skeletal elements in an hindlimb region. http://purl.obolibrary.org/obo/GO_0099175 regulation of postsynapse organization http://purl.obolibrary.org/obo/GO_0050807 regulation of synapse organization Any process that modulates the physical form of a postsynapse. http://purl.obolibrary.org/obo/UBERON_0001442 skeleton of manus http://purl.obolibrary.org/obo/UBERON_0006717 autopodial skeleton Subdivision of skeleton that is the collection of all skeletal elements in a manus, which is the distal section of the anterior forelimb skeleton consisting of the mesopodium, the metapodium and the acropodium (e.g. including the wrist, palm, and fingers)[Phenoscape]. http://purl.obolibrary.org/obo/GO_0106135 negative regulation of cardiac muscle cell contraction http://purl.obolibrary.org/obo/GO_0055118 negative regulation of cardiac muscle contraction Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle cell contraction. http://purl.obolibrary.org/obo/GO_0120192 tight junction assembly http://purl.obolibrary.org/obo/GO_0007043 cell-cell junction assembly A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a tight junction. A tight junction seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other. http://purl.obolibrary.org/obo/UBERON_0001443 chest http://purl.obolibrary.org/obo/UBERON_0009569 subdivision of trunk Subdivision of trunk proper, which is demarcated from the neck by the plane of the superior thoracic aperture and from the abdomen internally by the inferior surface of the diaphragm and externally by the costal margin and associated with the thoracic vertebral column and ribcage and from the back of the thorax by the external surface of the posterolateral part of the rib cage, the anterior surface of the thoracic vertebral column and the posterior axillary lines; together with the abdomen and the perineum, it constitutes the trunk proper[FMA]. http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure A part of a cellular organism consisting of a material entity with granularity above the level of a protein complex but below that of an anatomical system. Note that cellular organisms exclude viruses. http://purl.obolibrary.org/obo/UBERON_0001445 skeleton of pes http://purl.obolibrary.org/obo/UBERON_0006717 autopodial skeleton Subdivision of skeleton that is the collection of all skeletal elements in a pes, which is the distal section of the posterior hindlimb skeleton consisting of the mesopodium, the metapodium and the acropodium (e.g. including the ankle, sole, and toes)[Phenoscape]. http://purl.obolibrary.org/obo/PATO_0070001 neurogliaform morphology http://purl.obolibrary.org/obo/PATO_0070026 multipolar neuron morphology A cell morphology that inheres in neurons which have a small round soma, a large number of short, smooth, or slightly beaded primary dendrites that give rise to only a few secondary branches, and a branched axon that establishes a dense axonal mesh with thin shafts. http://purl.obolibrary.org/obo/UBERON_0001446 fibula http://purl.obolibrary.org/obo/UBERON_0015013 fibula endochondral element The major postaxial endochondral bone in the posterior zeugopod[Phenoscape]. http://purl.obolibrary.org/obo/GO_0120308 axonemal outer doublet assembly http://purl.obolibrary.org/obo/GO_0022607 cellular component assembly The aggregation, arrangement and bonding together of a set of components to form an axonemal outer doublet, a part of an axoneme consisting of a doublet microtubule. http://purl.obolibrary.org/obo/CL_4023040 L2/3-6 intratelencephalic projecting glutamatergic neuron http://purl.obolibrary.org/obo/CL_4023008 intratelencephalic-projecting glutamatergic cortical neuron An intratelencephalic-projecting glutamatergic neuron with a soma found in cortical layers L2/3-6. http://purl.obolibrary.org/obo/CL_4023049 L5 intratelencephalic projecting glutamatergic neuron of the primary motor cortex http://purl.obolibrary.org/obo/CL_4030064 L5 intratelencephalic projecting glutamatergic neuron An intratelencephalic-projecting glutamatergic neuron with a soma found in L5 of the primary motor cortex. http://purl.obolibrary.org/obo/UBERON_0001447 tarsal bone http://purl.obolibrary.org/obo/UBERON_0015050 tarsus endochondral element A bone that is part of the tarsal skeleton. Examples: calcaneus, talus, centralia. http://purl.obolibrary.org/obo/CL_4023086 T Martinotti neuron http://purl.obolibrary.org/obo/CL_4023076 Martinotti neuron A Martinotti neuron that has axons that form a horizontal ramification, making it T-shaped. http://purl.obolibrary.org/obo/UBERON_0001448 metatarsal bone http://purl.obolibrary.org/obo/UBERON_0015036 pedal digit metatarsal endochondral element The metatarsus or metatarsal bones are a group of five long bones in the pes located between the tarsal bones of the hind- and mid-pes and the phalanges of the toes. Lacking individual names, the metatarsal bones are numbered from the medial side (side of big toe): the first, second, third, fourth, and fifth metatarsal. The metatarsals are analogous to the metacarpal bones of the manus. [WP,unvetted]. http://purl.obolibrary.org/obo/CL_4023065 meis2 expressing cortical GABAergic cell http://purl.obolibrary.org/obo/CL_0010012 cerebral cortex neuron A GABAergic cell located in the cerebral cortex that expresses meis2. http://purl.obolibrary.org/obo/UBERON_0001449 phalanx of pes http://purl.obolibrary.org/obo/UBERON_0015030 pedal digit phalanx endochondral element A phalanx that is part of a hindlimb autopod[Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0140667 regulation of oxytocin production http://purl.obolibrary.org/obo/GO_0010468 regulation of gene expression Any process that modulates the frequency, rate, or extent of production of oxytocin. http://purl.obolibrary.org/obo/UBERON_0039222 cystic artery http://purl.obolibrary.org/obo/UBERON_0015796 liver blood vessel An artery that supplies oxygenated blood to the cystic duct. http://purl.obolibrary.org/obo/UBERON_0001457 skin of eyelid http://purl.obolibrary.org/obo/UBERON_1000021 skin of face A zone of skin that is part of a eyelid [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_7500062 tibial tuberosity http://purl.obolibrary.org/obo/UBERON_4100000 skeletal element projection The tibial tuberosity is on the anterior side of a tibia and is where a patella ligament attaches. http://purl.obolibrary.org/obo/UBERON_0001458 skin of lip http://purl.obolibrary.org/obo/UBERON_1000021 skin of face A zone of skin that is part of a lip [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_8410003 ductal plate http://purl.obolibrary.org/obo/UBERON_0010000 multicellular anatomical structure In human, ductal plate is a double-layered cylindrical structure of bile duct epithelium that surrounds the portal ramifications by the eighth gestational week. After approximately the 12th gestational week, remodelling of ductal plate begins, and maturity is attained by the end of gestation or early postnatal period. http://purl.obolibrary.org/obo/UBERON_0001459 skin of external ear http://purl.obolibrary.org/obo/UBERON_0001084 skin of head A zone of skin that is part of a external ear [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_8410020 venule of appendix http://purl.obolibrary.org/obo/UBERON_0001979 venule A venule located in the vermiform appendix. http://purl.obolibrary.org/obo/UBERON_0001460 arm http://purl.obolibrary.org/obo/UBERON_0008785 upper limb segment The part of the forelimb extending from the shoulder to the autopod[cjm]. http://purl.obolibrary.org/obo/UBERON_8410028 arteriole of appendix http://purl.obolibrary.org/obo/UBERON_0001980 arteriole An arteriole located in the vermiform appendix. http://purl.obolibrary.org/obo/UBERON_0001461 elbow http://purl.obolibrary.org/obo/UBERON_0008785 upper limb segment The elbow is the region surrounding the elbow-joint-the ginglymus or hinge joint in the middle of the arm. Three bones form the elbow joint: the humerus of the upper arm, and the paired radius and ulna of the forearm. The bony prominence at the very tip of the elbow is the olecranon process of the ulna, and the inner aspect of the elbow is called the antecubital fossa. [WP,unvetted,human-specific]. http://purl.obolibrary.org/obo/UBERON_8410030 lymphatic vessel of appendix http://purl.obolibrary.org/obo/UBERON_0001473 lymphatic vessel A lymphatic vessel located in the vermiform appendix. http://purl.obolibrary.org/obo/UBERON_0001464 hip http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision The hip region is located lateral to the gluteal region (i.e. the buttock), inferior to the iliac crest, and overlying the greater trochanter of the thigh bone. In adults, three of the bones of the pelvis have fused into the hip bone which forms part of the hip region. The hip joint, scientifically referred to as the acetabulofemoral joint (art. coxae), is the joint between the femur and acetabulum of the pelvis and its primary function is to support the weight of the body in both static (e.g. standing) and dynamic (e.g. walking or running) postures. [WP,modified]. http://purl.obolibrary.org/obo/UBERON_8410037 high endothelial venule http://purl.obolibrary.org/obo/UBERON_0035428 postcapillary venule High endothelial venules are specialized blood vessels adapted for lymphocyte trafficking. They form a spatially organized network, which controls both the type of lymphocyte and the site of entry into lymphoid tissues. Uniquely, high endothelial venules express vascular addressins that regulate lymphocyte entry into lymphoid organs. They perform this function in all lymphoid organs except the spleen. http://purl.obolibrary.org/obo/UBERON_0001465 knee http://purl.obolibrary.org/obo/UBERON_0008784 lower limb segment A segment of the hindlimb that corresponds to the joint connecting a hindlimb stylopod and zeugopod. http://purl.obolibrary.org/obo/UBERON_8410039 high endothelial venule of appendix http://purl.obolibrary.org/obo/UBERON_8410037 high endothelial venule A high endothelial venule that is located in the vermiform appendix. http://purl.obolibrary.org/obo/UBERON_0001466 pedal digit http://purl.obolibrary.org/obo/UBERON_0002544 digit A digit that is part of a pes (foot). http://purl.obolibrary.org/obo/UBERON_8410040 high endothelial venule of small intestine Peyer's patch http://purl.obolibrary.org/obo/UBERON_8410037 high endothelial venule A high endothelial venule that is located in a Peyer's patch in the small intestine. http://purl.obolibrary.org/obo/UBERON_0001467 shoulder http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision A subdivision of the pectoral complex consisting of the structures in the region of the shoulder joint (which connects the humerus, scapula and clavicle). http://purl.obolibrary.org/obo/UBERON_8410044 vein of appendix http://purl.obolibrary.org/obo/UBERON_0001638 vein A vein that is part of a vermiform appendix. http://purl.obolibrary.org/obo/UBERON_0001468 intervertebral joint http://purl.obolibrary.org/obo/UBERON_0002216 symphysis The joint between adjacent vertebral bodies. May be composed of the nucleus pulposus, annular ligament, and the anterior and posterior longitudinal ligaments. http://purl.obolibrary.org/obo/UBERON_8410045 artery of appendix http://purl.obolibrary.org/obo/UBERON_0001637 artery An artery that is part of a vermiform appendix. http://purl.obolibrary.org/obo/UBERON_0001469 sternoclavicular joint http://purl.obolibrary.org/obo/UBERON_0011108 synovial joint of pectoral girdle The sternoclavicular articulation is a double arthrodial joint composed of two portions separated by an articular disc. The parts entering into its formation are the sternal end of the clavicle, the upper and lateral part of the manubrium sterni, and the cartilage of the first rib, visible from the outside as the suprasternal notch. The articular surface of the clavicle is much larger than that of the sternum, and is invested with a layer of cartilage, which is considerably thicker than that on the latter bone. The ligaments of this joint are: Articular capsule Anterior sternoclavicular ligament Posterior sternoclavicular ligament Interclavicular ligament Costoclavicular ligament Articular disk [WP,unvetted]. http://purl.obolibrary.org/obo/UBERON_8410049 serosal nerve fiber of appendix http://purl.obolibrary.org/obo/UBERON_0006134 nerve fiber A nerve fiber that is located in the serosa of vermiform appendix. http://purl.obolibrary.org/obo/UBERON_0001470 glenohumeral joint http://purl.obolibrary.org/obo/UBERON_0016884 shoulder joint The glenohumeral joint, commonly known as the shoulder joint, is a multiaxial synovial ball and socket joint and involves articulation between the glenoid fossa of the scapula (shoulder blade) and the head of the humerus (upper arm bone). [WP,unvetted]. http://purl.obolibrary.org/obo/UBERON_8420000 hair of scalp http://purl.obolibrary.org/obo/UBERON_0016446 hair of head Hair that grows on the scalp. http://purl.obolibrary.org/obo/UBERON_0001471 skin of prepuce of penis http://purl.obolibrary.org/obo/UBERON_0001331 skin of penis The loose fold of skin that covers the penis. http://purl.obolibrary.org/obo/PATO_0070044 anatomical structure quality http://purl.obolibrary.org/obo/PATO_0001241 physical object quality A quality of continuant that exist at the anatomical level of organisation and anything under it. This includes, but is not limited to, cells , tissues, and components. http://purl.obolibrary.org/obo/UBERON_0001472 vaginal venous plexus http://purl.obolibrary.org/obo/UBERON_0006876 vasculature of organ The vaginal plexuses are placed at the sides of the vagina; they communicate with the uterine, vesical, and hemorrhoidal plexuses, and are drained by the vaginal veins, one on either side, into the hypogastric veins. [WP,unvetted]. http://purl.obolibrary.org/obo/PATO_0070045 anatomical histological quality http://purl.obolibrary.org/obo/PATO_0070044 anatomical structure quality A quality inhering in an anotomical structure by virtue of its capacity to be stained by specific histological dyes. http://purl.obolibrary.org/obo/UBERON_0001473 lymphatic vessel http://purl.obolibrary.org/obo/UBERON_0000055 vessel A vessel that contains or conveys lymph, that originates as an interfibrillar or intercellular cleft or space in a tissue or organ, and that if small has no distinct walls or walls composed only of endothelial cells and if large resembles a vein in structure[BTO]. http://purl.obolibrary.org/obo/PATO_0070046 neutrophillic http://purl.obolibrary.org/obo/PATO_0070045 anatomical histological quality An affinity inhering in an anatomical structure by virtue of the bearer exhibiting a molecular interaction that stains and colors, pale-pink, with Wright-Giemsa stain. http://purl.obolibrary.org/obo/UBERON_0001474 bone element http://purl.obolibrary.org/obo/UBERON_0004765 skeletal element Skeletal element that is composed of bone tissue. http://purl.obolibrary.org/obo/PATO_0070047 polychromatophilic http://purl.obolibrary.org/obo/PATO_0070045 anatomical histological quality An affinity inhering in an anatomical structure by virtue of the bearer exhibiting a molecular interaction for both basic and acid stains under specific pH conditions. http://purl.obolibrary.org/obo/UBERON_0001476 deltoid http://purl.obolibrary.org/obo/UBERON_0034908 scapular muscle A muscle of shoulder which attaches to the scapula, clavicle and humerus.[FMA,generalized]. http://purl.obolibrary.org/obo/UBERON_8450001 egg follicle http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure An individual reproductive unit containing a single oocyte and one or several layers of support cells (Armstrong et al., 2020). http://purl.obolibrary.org/obo/CL_0009091 Leydig stem cell http://purl.obolibrary.org/obo/CL_0000034 stem cell A stem cell found in the interstitial compartment of the neonatal testis; it is capable of self-renewal as well as differentiation into steroidogenic cells (adult Leydig cells). Intermediate stages of development include progenitor Leydig cells and immature Leydig cells. http://purl.obolibrary.org/obo/CL_0009099 fibro/adipogenic progenitor cell http://purl.obolibrary.org/obo/CL_0008019 mesenchymal cell A progenitor cell that is a tissue-resident mesenchymal cell, important for skeletal muscle regeneration, and able to differentiate into both adipocytes or fibroblasts. http://purl.obolibrary.org/obo/CL_0009115 lymph node lymphatic vessel endothelial cell http://purl.obolibrary.org/obo/CL_0002138 endothelial cell of lymphatic vessel An endothelial cell located in a lymph node lymphatic vessel. http://purl.obolibrary.org/obo/CL_0009116 progenitor cell of mammary luminal epithelium http://purl.obolibrary.org/obo/CL_0011026 progenitor cell A progenitor cell with the potential to differentiate into luminal epithelial cells of mammary glands. In mouse, CD61 and c-kit were found to be coexpressed by the majority of, but not all, committed luminal progenitor cells. http://purl.obolibrary.org/obo/UBERON_0001479 sesamoid bone http://purl.obolibrary.org/obo/UBERON_0013631 sesamoid element A sesamoid element that is composed of bone tissue. http://purl.obolibrary.org/obo/PATO_0040072 high nuclear/cytoplasmic ratio http://purl.obolibrary.org/obo/PATO_0001396 cellular quality A quality inhering in a cell by virtue of the cell having a high nuclear/cytoplasmic ratio. http://purl.obolibrary.org/obo/UBERON_0001480 proximal carpal bone http://purl.obolibrary.org/obo/UBERON_0015078 proximal carpal endochondral element A carpal bone that proximally_connected_to a forelimb zeugopod skeleton. http://purl.obolibrary.org/obo/UBERON_7500107 sphenovomerine suture http://purl.obolibrary.org/obo/UBERON_0009199 facial suture A suture joining a sphenoid bone with the alae of a vomer to form a schindylesis type of joint. http://purl.obolibrary.org/obo/UBERON_0001482 muscle of shoulder http://purl.obolibrary.org/obo/UBERON_0014892 skeletal muscle organ, vertebrate Any muscle organ that is part of a shoulder [Automatically generated definition]. http://purl.obolibrary.org/obo/CL_0003002 G1 retinal ganglion cell http://purl.obolibrary.org/obo/CL_0000740 retinal ganglion cell A retinal ganglion cell that has a small dendritic field and a medium dendritic arbor with post sympatic terminals in sublaminar layer S3. http://purl.obolibrary.org/obo/CL_4023064 caudal ganglionic eminence derived interneuron http://purl.obolibrary.org/obo/CL_0010011 cerebral cortex GABAergic interneuron An interneuron that is derived from the caudal ganglionic eminence. http://purl.obolibrary.org/obo/UBERON_8480026 skin of iliac crest region http://purl.obolibrary.org/obo/UBERON_0001415 skin of pelvis A zone of skin that is above the iliac crest in the pelvic girdle bone/zone. http://purl.obolibrary.org/obo/UBERON_0001483 skin of shoulder http://purl.obolibrary.org/obo/UBERON_0000014 zone of skin A zone of skin that is part of a shoulder region. http://purl.obolibrary.org/obo/UBERON_8480030 skin of breast http://purl.obolibrary.org/obo/UBERON_0001868 skin of chest A zone of skin that is part of the breast. http://purl.obolibrary.org/obo/UBERON_0001484 articular capsule http://purl.obolibrary.org/obo/UBERON_0000094 membrane organ An articular capsule (or joint capsule) is an envelope surrounding a synovial joint. [WP,unvetted]. http://purl.obolibrary.org/obo/UBERON_8480037 subserosa of fallopian tube http://purl.obolibrary.org/obo/UBERON_0012375 subserosa Subserosa that is part of the uterine tube. It contains loose connective tissue, blood vessels and lymphatic tissue. http://purl.obolibrary.org/obo/UBERON_0001485 knee joint http://purl.obolibrary.org/obo/UBERON_0011139 synovial limb joint The knee joint joins the thigh with the leg and consists of two articulations: one between the femur and tibia, and one between the femur and patella. It is the largest and most complicated joint in the human body. The knee is a mobile trocho-ginglymus (i.e. a pivotal hinge joint), which permits flexion and extension as well as a slight medial and lateral rotation[WP,unvetted]. http://purl.obolibrary.org/obo/UBERON_8600038 placental disc http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure A disc-shaped structure that is part of the placenta. A placental disc supports fetal development through the exchange of nutrients between maternal and fetal bloodstreams. The placental disc is structured to keep the blood streams separate, while maximizing surface area for the transport of nutrients between them, to maintain an immunological barrier. http://purl.obolibrary.org/obo/UBERON_0001487 pes joint http://purl.obolibrary.org/obo/UBERON_0011139 synovial limb joint A skeletal joint that is part of a pes [Automatically generated definition]. http://purl.obolibrary.org/obo/CL_4307033 Astro-NT NN_1 Mecom astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301589 Astro-NT NN_1 astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Dao (Mmus), Mecom (Mmus), Fbln5 (Mmus), Prelp (Mmus). It is distinguished from other Astro-NT NN_1 cells by expression of Mecom, Prelp. These cells are located in the Medulla, Cerebellum, brain , in or close to the regions: Ventral cochlear nucleus, Paraflocculus, Flocculus, Dorsal cochlear nucleus . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5213 Astro-NT NN_1. http://purl.obolibrary.org/obo/UBERON_0001488 ankle joint http://purl.obolibrary.org/obo/UBERON_0011139 synovial limb joint A joint that connects the hindlimb autopod and zeugopod skeletons. http://purl.obolibrary.org/obo/CL_4307041 Astro-TE NN_1 Jph4 astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301591 Astro-TE NN_1 astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Myoc (Mmus), Sptbn2 (Mmus), Alpk1 (Mmus). It is distinguished from other Astro-TE NN_1 cells by expression of Myoc, Jph4, Alpk1. It is glutamatergic (inferred from expression of Aldh1a1, Slc17a7). These cells are located in the Isocortex, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5221 Astro-TE NN_1. http://purl.obolibrary.org/obo/UBERON_0001489 manus joint http://purl.obolibrary.org/obo/UBERON_0011139 synovial limb joint A skeletal joint that is part of a manus (hand) [Automatically generated definition]. http://purl.obolibrary.org/obo/CL_4307028 Astro-NT NN_1 Galnt15 astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301589 Astro-NT NN_1 astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gfap (Mmus), Galnt15 (Mmus), Agt (Mmus). It is distinguished from other Astro-NT NN_1 cells by expression of Galnt15. These cells are located in the Cerebellum, brain , in or close to the regions: arbor vitae . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5208 Astro-NT NN_1. http://purl.obolibrary.org/obo/UBERON_0001490 elbow joint http://purl.obolibrary.org/obo/UBERON_0011139 synovial limb joint A joint that connects the forelimb zeugopod and stylopod skeletons[Obol]. http://purl.obolibrary.org/obo/CL_4301589 Astro-NT NN_1 astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4300358 subcortical astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gfap (Mmus), Lhfpl3 (Mmus), Gria1 (Mmus), Hopx (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1159 Astro-NT NN_1. http://purl.obolibrary.org/obo/UBERON_0001491 wrist joint http://purl.obolibrary.org/obo/UBERON_0001489 manus joint A joint connecting the forelimb zeugopod skeleton with the carpal skeleton. http://purl.obolibrary.org/obo/CL_4072013 A16 dopaminergic neuron http://purl.obolibrary.org/obo/CL_1001434 olfactory bulb interneuron A type of dopaminergic interneuron located in the glomerular layer of the main olfactory bulb, characterized by the co-release of dopamine and GABA, and involved in modulating sensory input within olfactory circuits. http://purl.obolibrary.org/obo/UBERON_0001493 axillary nerve http://purl.obolibrary.org/obo/UBERON_0003433 arm nerve The axillary nerve is a nerve of the human body, that comes off the posterior cord of the brachial plexus at the level of the axilla (armpit) and carries nerve fibers from C5 and C6. The axillary nerve travels through the quadrangular space with the posterior circumflex humeral artery and vein. [WP,unvetted]. http://purl.obolibrary.org/obo/CL_4072011 A14 dopaminergic neuron http://purl.obolibrary.org/obo/CL_2000029 central nervous system neuron A type of dopaminergic neuron located in the periventricular nucleus of the hypothalamus and projecting to the lateral septum and the median eminence. It is contributing to neuroendocrine functions, locomotion and stress regulation. http://purl.obolibrary.org/obo/UBERON_0001495 pectoral muscle http://purl.obolibrary.org/obo/UBERON_0008196 muscle of pectoral girdle Muscles of the upper chest. The term may refer to one of two muscles, the pectoralis major and pectoralis minor. The former is a thick muscle in the anterior portion of the chest. Its action involves flexion, medial rotation, and adduction of the humerus. The latter is a thin muscle located beneath the pectoralis major. Its action involves lowering the scapula and raising the ribs. http://purl.obolibrary.org/obo/CL_4072102 Purkinje layer interneuron http://purl.obolibrary.org/obo/CL_4023057 cerebellar inhibitory GABAergic interneuron A type of GABAergic interneuron residing in the Purkinje cell layer of the cerebellar cortex. http://purl.obolibrary.org/obo/UBERON_0001496 ascending aorta http://purl.obolibrary.org/obo/UBERON_0001515 thoracic aorta The ascending aorta is the portion of the aorta in a two-pass circulatory system that lies between the heart and the arch of aorta[GO]. A portion of the aorta commencing at the upper part of the base of the left ventricle, on a level with the lower border of the third costal cartilage behind the left half of the sternum; it passes obliquely upward, forward, and to the right, in the direction of the heart's axis, as high as the upper border of the second right costal cartilage, describing a slight curve in its course, and being situated, about 6 cm behind the posterior surface of the sternum. The total length is about 5 cm in length [Wikipedia]. http://purl.obolibrary.org/obo/CL_4301611 commited oligodendrocyte precursor (Mmus) http://purl.obolibrary.org/obo/CL_4300367 oligodendrocyte (Mmus) A committed oligodendrocyte precursor of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gpr17 (Mmus), Bmp4 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1181 COP NN_1. http://purl.obolibrary.org/obo/UBERON_0001497 muscle of pelvic girdle http://purl.obolibrary.org/obo/UBERON_0010890 pelvic complex muscle Any muscle organ that is part of a pelvic girdle [Automatically generated definition]. http://purl.obolibrary.org/obo/CL_4033136 inferior mesenteric ganglion SP neuron http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron A sympathetic neuron that has the soma located in the inferior mesenteric ganglion and expresses the marker substance P (SP). http://purl.obolibrary.org/obo/UBERON_0001498 muscle of pes http://purl.obolibrary.org/obo/UBERON_0003663 hindlimb muscle Any muscle organ that is part of a pes [Automatically generated definition]. http://purl.obolibrary.org/obo/CL_4300360 olfactory areas astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_0000127 astrocyte A transcriptomically defined type of astrocyte located exclusively in the olfactory areas. It is distinguished from other cells in the brain by selective expression of Gja1 (Mmus), Hs3st3a1 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Subclass:320 Astro-OLF NN. http://purl.obolibrary.org/obo/UBERON_0001499 muscle of arm http://purl.obolibrary.org/obo/UBERON_0003662 forelimb muscle A muscle organ that is part of an arm [Automatically generated definition]. http://purl.obolibrary.org/obo/CL_4307069 beta1-tancyte (Mmus) http://purl.obolibrary.org/obo/CL_4301603 Tanycyte NN_2 tanycyte (Mmus) A beta1-tanycyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gpr50 (Mmus), Frzb (Mmus), Foxd2os (Mmus). It is distinguished from other Tanycyte NN_2 cells by expression of Col25a1, C230072F16Rik. These cells are located in the Hypothalamus, brain , in or close to the regions: third ventricle, Arcuate hypothalamic nucleus . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5249 Tanycyte NN_2. http://purl.obolibrary.org/obo/UBERON_0001500 muscle of manus http://purl.obolibrary.org/obo/UBERON_0003662 forelimb muscle Any muscle organ that is part of a manus [Automatically generated definition]. http://purl.obolibrary.org/obo/CL_4301571 DCO Il22 Gly-Gaba_1 cerebellar neuron (Mmus) http://purl.obolibrary.org/obo/CL_4300348 DCO Il22 Gly-Gaba cerebellar neuron (Mmus) A cerebellar neuron of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Il22 (Mmus), Rftn1 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1141 DCO Il22 Gly-Gaba_1. http://purl.obolibrary.org/obo/UBERON_0001508 arch of aorta http://purl.obolibrary.org/obo/UBERON_0001515 thoracic aorta The convex portion of the aorta between the ascending and descending parts of the aorta; branches from it include the brachiocephalic trunk, the left common carotid artery, and the left subclavian artery; the brachiocephalic trunk further splits to form the right subclavian artery and the right common carotid artery. http://purl.obolibrary.org/obo/CL_4307085 CHOR NN_1 Slc17a8 choroid plexus epithelial cell (Mmus) http://purl.obolibrary.org/obo/CL_4301608 choroid plexus epithelial cell (Mmus) A choroid plexus epithelial cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of 2900040C04Rik (Mmus), Slc17a8 (Mmus). It is distinguished from other CHOR NN cells by expression of Slc17a8. It is glutamatergic (inferred from expression of Slc17a8). These cells are located in the brain , in or close to the regions: choroid plexus, lateral ventricle . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5265 CHOR NN_1. http://purl.obolibrary.org/obo/UBERON_0001510 skin of knee http://purl.obolibrary.org/obo/UBERON_0001511 skin of leg A zone of skin that is part of a knee [Automatically generated definition]. http://purl.obolibrary.org/obo/CL_4307053 Astro-OLF NN_2 Slc25a34 astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301597 Astro-OLF NN_2 astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Aqp4 (Mmus), Hs3st3a1 (Mmus), Slc25a34 (Mmus), C4b (Mmus). It is distinguished from other Astro-OLF NN_2 cells by expression of Slc25a34, C4b. These cells are located in the Olfactory areas, brain , in or close to the regions: Main olfactory bulb, outer plexiform layer, Main olfactory bulb . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5233 Astro-OLF NN_2. http://purl.obolibrary.org/obo/UBERON_0001511 skin of leg http://purl.obolibrary.org/obo/UBERON_0003532 hindlimb skin A zone of skin that is part of a leg [Automatically generated definition]. http://purl.obolibrary.org/obo/CL_4307086 OPC NN_1 Neil3 oligodendrocyte precursor cell (Mmus) http://purl.obolibrary.org/obo/CL_4300366 oligodendrocyte precursor cell (Mmus) A oligodendrocyte precursor cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Pdgfra (Mmus), Pclaf (Mmus), Mki67 (Mmus), Foxg1 (Mmus). It is distinguished from other OPC NN_1 cells by expression of Neil3, Foxg1. These cells are located in the Isocortex, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5266 OPC NN_1. http://purl.obolibrary.org/obo/UBERON_0001512 skin of ankle http://purl.obolibrary.org/obo/UBERON_0001513 skin of pes A zone of skin that is part of an ankle [Automatically generated definition]. http://purl.obolibrary.org/obo/CL_4307109 OEC NN_1 Adamts12 olfactory ensheathing cell (Mmus) http://purl.obolibrary.org/obo/CL_4301615 olfactory ensheathing cell (Mmus) A olfactory ensheathing cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Cldn5 (Mmus), Adamts12 (Mmus). It is distinguished from other OEC cells by expression of Adamts12. These cells are located in the brain , in or close to the regions: olfactory nerve layer of main olfactory bulb . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5289 OEC NN_1. http://purl.obolibrary.org/obo/UBERON_0001513 skin of pes http://purl.obolibrary.org/obo/UBERON_0015790 autopod skin A zone of skin that is part of a pes [Automatically generated definition]. http://purl.obolibrary.org/obo/CL_4300101 STR D1 Gaba direct pathway medium spiny neuron (Mmus) http://purl.obolibrary.org/obo/CL_4023026 direct pathway medium spiny neuron A direct pathway medium spiny neuron of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Prkch (Mmus), Slc32a1 (Mmus), Drd1 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Subclass:061 STR D1 Gaba. http://purl.obolibrary.org/obo/UBERON_0001514 descending aorta http://purl.obolibrary.org/obo/UBERON_0005800 section of aorta The descending aorta is the portion of the aorta in a two-pass circulatory system from the arch of aorta to the point where it divides into the common iliac arteries[GO]. The descending aorta is part of the aorta, the largest artery in the body. The descending aorta is the part of the aorta beginning at the aortic arch that runs down through the chest and abdomen. The descending aorta is divided into two portions, the thoracic and abdominal, in correspondence with the two great cavities of the trunk in which it is situated. Within the abdomen, the descending aorta branches into the two common iliac arteries which serve the legs. [WP,unvetted]. http://purl.obolibrary.org/obo/GO_0160274 beige fat cell differentiation http://purl.obolibrary.org/obo/GO_0045444 fat cell differentiation The process in which a white fat cell acquires specialized features of a beige adipocyte. Beige adipocytes reside within white adipose tissue and can be induced to produce heat in response to cold exposure or certain stimuli, resembling brown adipocytes. http://purl.obolibrary.org/obo/UBERON_0001515 thoracic aorta http://purl.obolibrary.org/obo/UBERON_0005800 section of aorta The part of the aorta that extends from the origin at the heart to the diaphragm, and from which arises numerous branches that supply oxygenated blood to the chest cage and the organs within the chest. http://purl.obolibrary.org/obo/GO_7770012 negative regulation of starch biosynthetic process http://purl.obolibrary.org/obo/GO_0045912 negative regulation of carbohydrate metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of starch. http://purl.obolibrary.org/obo/UBERON_0001516 abdominal aorta http://purl.obolibrary.org/obo/UBERON_0005800 section of aorta Abdominal part of aorta: the distal part of the descending aorta, which is the continuation of the thoracic part and gives rise to the inferior phrenic, lumbar, median sacral, superior and inferior mesenteric, middle suprarenal, renal, and testicular or ovarian arteries, and celiac trunk[BTO]. The abdominal aorta is the largest artery in the abdominal cavity. As part of the aorta, it is a direct continuation of descending aorta(of the thorax). [WP,unvetted]. http://purl.obolibrary.org/obo/CL_0020000 gut mesenchymal lymphoid tissue organizer cell http://purl.obolibrary.org/obo/CL_0011026 progenitor cell A mesenchymal stromal cell found in the gut during development, and interacts with lymphoid tissue inducer (LTi) cells to drive secondary lymphoid organ formation (Prados et al., 2021). It expresses LTβR, PDGFRα, and VCAM, and upon activation secretes chemokines(e.g. CXCL13) and cytokines to organise lymphoid tissue architecture and recruit immune cells in both mice and humans (Denton el al., 2019; Elmentaite et al., 2021). As a multipotent progenitor, an mLTo cell differentiates into adult stromal subsets, including fibroblastic reticular cells (FRCs) (Prados et al., 2021), and its descendants persist in the adult gut-associated lymphoid tissues to maintain immune homeostasis(Denton el al., 2019; Lütge et al., 2021). http://purl.obolibrary.org/obo/UBERON_0001517 skin of elbow http://purl.obolibrary.org/obo/UBERON_0002427 arm skin A zone of skin that is part of a elbow [Automatically generated definition]. http://purl.obolibrary.org/obo/CL_0020001 V1delta gamma-delta T cell http://purl.obolibrary.org/obo/CL_0000800 mature gamma-delta T cell A mature gamma-delta T Cell with T cell receptors consisting of the Vδ1 segment paired with various V gamma chains. This cell is enriched in the gut, skin (Davey et al., 2018) and the female reproductive tract (Wu et al., 2022). It exhibits potent cytotoxic capabilities through perforin/granzyme and death receptor pathways. http://purl.obolibrary.org/obo/UBERON_0001518 skin of wrist http://purl.obolibrary.org/obo/UBERON_0001519 skin of manus A zone of skin that is part of a wrist [Automatically generated definition]. http://purl.obolibrary.org/obo/CL_0020002 mucosal-associated invariant T cell, human http://purl.obolibrary.org/obo/CL_0000940 mucosal-associated invariant T cell A mucosal-associated invariant T (MAIT) cell found in various tissues including human blood, liver, gut, and lung, characterised by a semi-invariant T cell receptor (TCR) comprising TRAV1-2 (Vα7.2) predominantly paired with TRAJ33, and high expression of CD161. Upon activation, MAIT cells produce inflammatory cytokines, including IFN-γ, TNF-α, and IL-17. http://purl.obolibrary.org/obo/UBERON_0001519 skin of manus http://purl.obolibrary.org/obo/UBERON_0015790 autopod skin A zone of skin that is part of a manus [Automatically generated definition]. http://purl.obolibrary.org/obo/CL_0020003 internal globus pallidus core projecting neuron http://purl.obolibrary.org/obo/CL_0012001 neuron of the forebrain A projection neuron that has its soma located in the internal segment of the globus pallidus (GPi) of primates, in the central “core” region. It expresses parvalbumin, is primarily GABAergic, and projects to motor thalamic nuclei including the ventral anterior, ventrolateral, and ventromedial nuclei. In the rodent homolog (entopeduncular nucleus), the core subregion is characterized by concentrated parvalbumin-positive neurons targeting the ventral anterior-ventral lateral thalamic nucleus and receives inputs from the dorsolateral striatum innervated by sensorimotor cortices (Miyamoto & Fukuda, 2022). This neuron corresponds to the sensorimotor output population of the GPi, as demonstrated in human tissue and cross-species comparative studies (Wallace et al., 2017) and by classic tracing in primates (Parent & De Bellefeuille, 1982; Parent et al., 2001). http://purl.obolibrary.org/obo/UBERON_0001529 brachiocephalic artery http://purl.obolibrary.org/obo/UBERON_0004573 systemic artery The short first aortic arch branch and divides into the right subclavian artery and the right common carotid artery. http://purl.obolibrary.org/obo/CL_0020004 internal globus pallidus shell projection neuron http://purl.obolibrary.org/obo/CL_0012001 neuron of the forebrain A projection neuron that has its soma located in the internal segment of the globus pallidus (GPi), in the peripheral 'shell' region. In mice and primates, it expresses somatostatin and shows dual expression of GABAergic and glutamatergic markers, enabling co-release of GABA and glutamate (Wallace et al., 2017). It projects primarily to the lateral habenula (Parent & De Bellefeuille, 1982; Wallace et al., 2017), forming the limbic/aversive output stream of the GPi. http://purl.obolibrary.org/obo/UBERON_0001530 common carotid artery plus branches http://purl.obolibrary.org/obo/UBERON_0004573 systemic artery A bilaterally paired branched artery that originates from the aortic arches and divides into and includes as parts the internal and external carotid arteries[cjm]. http://purl.obolibrary.org/obo/CL_0020005 spiral ligament fibrocyte http://purl.obolibrary.org/obo/CL_0002665 otic fibrocyte An otic fibrocyte that is part of the spiral ligament. This cell is crucial in maintaining the endocochlear potential, regulating blood flow, participating in immune responses by secreting chemokines including MCP-1 and MIP-2, and producing extracellular matrix proteins such as collagen and cochlin. http://purl.obolibrary.org/obo/UBERON_0001531 right common carotid artery plus branches http://purl.obolibrary.org/obo/UBERON_0001530 common carotid artery plus branches The rightmost of the two common carotid arteries, originating from in the neck from the brachiocephalic trunk. http://purl.obolibrary.org/obo/CL_0020006 OB-Dopa-GABA http://purl.obolibrary.org/obo/CL_0002613 striatum neuron A transcriptomically defined GABAergic neuron coexpressing dopamine located in the olfactory bulb and part of the striatum. http://purl.obolibrary.org/obo/UBERON_0001532 internal carotid artery http://purl.obolibrary.org/obo/UBERON_0003496 head blood vessel A terminal branch of the left or right common carotid artery which supplies oxygenated blood to the brain and eyes[MP]. http://purl.obolibrary.org/obo/UBERON_0001533 subclavian artery http://purl.obolibrary.org/obo/UBERON_0004573 systemic artery One of two laterally paired arteries that supplies the pectoral appendages, usually branching from the dorsal aorta. http://purl.obolibrary.org/obo/CL_0020007 dorso-striatal cholinergic-GABAergic neuron http://purl.obolibrary.org/obo/CL_0008061 GABA-Chol neuron A transcriptomically defined GABAergic neuron in the dorsal striatum. In mice and primates, it is defined by the coexpression of choline acetyltransferase (ChAT) together with the GABAergic markers glutamate decarboxylase 65 (GAD65/Gad2) and vesicular GABA transporter (VGAT/Slc32a1) (Lozovaya et al., 2018). http://purl.obolibrary.org/obo/UBERON_0001534 right subclavian artery http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure The subclavian artery that supplies the right pectoral appendage. http://purl.obolibrary.org/obo/CL_0020008 striatal cholinergic-GABAergic neuron http://purl.obolibrary.org/obo/CL_0008061 GABA-Chol neuron A large aspiny interneuron of the striatum that serves as the principal intrinsic source of acetylcholine while simultaneously releasing GABA. It is defined by coexpression of cholinergic markers (ChAT and VAChT/Slc18a3) and GABAergic markers (GAD65/Gad2 and VGAT/Slc32a1) (Lozovaya et al., 2018). This MGE-derived neuron maintains Lhx6 expression associated with dual-transmitter identity (Fragkouli et al., 2009; Marin et al., 2000). Morphologically, it possesses a large soma (20–50 μm diameter), 2–4 thick aspiny dendrites extending radially ~1 mm, and locally ramified axons with hundreds of thousands of varicosities (Wilson et al., 1990; Lim et al., 2014). http://purl.obolibrary.org/obo/UBERON_0001536 left common carotid artery plus branches http://purl.obolibrary.org/obo/UBERON_0001530 common carotid artery plus branches The leftmost of the two common carotid arteries, originating from the aortic arch in the thorax. http://purl.obolibrary.org/obo/CL_0020009 prototypic neuron http://purl.obolibrary.org/obo/CL_0012001 neuron of the forebrain A GABAergic neuron located in the external globus pallidus (GPe) that constitutes approximately two-thirds of all GPe neurons (Mallet et al., 2012, Dodson et al., 2015). Derived from the medial ganglionic eminence, this cell selectively expresses Nkx2-1, with roughly two-thirds co-expressing parvalbumin (PV) and one-third lacking it in mice (Mallet et al., 2012; Dodson et al., 2015). http://purl.obolibrary.org/obo/UBERON_0001544 popliteal vein http://purl.obolibrary.org/obo/UBERON_0001638 vein The popliteal vein course runs alongside the popliteal artery but carries the blood from the knee joint and muscles in the thigh and calf back to the heart. Its origin is defined by the junction of the posterior tibial vein and anterior tibial vein. It drains the peroneal vein before reaching the knee joint and turns into the femoral vein when leaving the adductor canal (also known as Hunter's canal). The popliteal artery extends from the femoral artery behind the popliteal fossa which is the space behind the knee. [WP,unvetted]. http://purl.obolibrary.org/obo/CL_0020010 arkypallidal neuron http://purl.obolibrary.org/obo/CL_0012001 neuron of the forebrain A GABAergic projection neuron located in the external segment of the globus pallidus (GPe) and defined by its exclusive projection to the dorsal striatum rather than to the subthalamic nucleus or basal ganglia output nuclei. In rodents and primates, it is characterized molecularly by expression of FOXP2, MEIS2, and NPAS1, and lacks expression of canonical pallidal markers NKX2-1 and LHX6 (Dodson et al., 2015; Abdi et al., 2015; Courtney et al., 2023). This neuron is GABAergic (GAD1/2⁺, SLC32A1/VGAT⁺) and typically PV⁻, forming the transcriptionally and developmentally LGE-derived subclass of GPe neurons (Dodson et al., 2015; Mallet et al., 2012). http://purl.obolibrary.org/obo/UBERON_0001545 anterior tibial vein http://purl.obolibrary.org/obo/UBERON_0010370 tibial vein A vein of the lower limb that carries blood from the anterior compartment of the leg to the popliteal vein which is forms when it joins with the posterior tibial vein. Like most deep veins, the anterior tibial vein is accompanied by an artery of the same name, the anterior tibial artery, along its course. [WP,unvetted]. http://purl.obolibrary.org/obo/CL_7770004 suprabasal cell http://purl.obolibrary.org/obo/CL_0000066 epithelial cell An epithelial cell that resides in the layer(s) immediately above the basal layer in stratified or pseudostratified epithelia. This cell mainly originates from basal cells and is found across various tissues, including skin, esophagus, oral mucosa, airway, and cornea. http://purl.obolibrary.org/obo/CL_4033098 inner wall Schlemm's canal endothelial cell http://purl.obolibrary.org/obo/CL_4033097 Schlemm's canal endothelial cell A Schlemm's canal endothelial cell that lines the inner wall of the Schlemm's canal. This cell exhibits a cobblestone appearance due to the significant biomechanical load it experiences, as well as the segmental flow of aqueous humor. The degree of biomechanical stress can lead to the formation of dome-like outpouchings known as giant vacuoles. In addition, the cell contains transcellular pores that mediate aqueous humor transport (Dautriche et al., 2015). This endothelial cell also displays prominent peripheral F-actin bands which help maintain structural integrity under pressure (Ethier et al., 2004). http://purl.obolibrary.org/obo/UBERON_0001547 small saphenous vein http://purl.obolibrary.org/obo/UBERON_0007318 saphenous vein The small saphenous vein (also lesser saphenous vein), is a relatively large vein of the superficial posterior leg. [WP,unvetted]. http://purl.obolibrary.org/obo/CL_4033099 outer wall Schlemm's canal endothelial cell http://purl.obolibrary.org/obo/CL_4033097 Schlemm's canal endothelial cell A Schlemm's canal endothelial cell that lines the outer wall of the Schlemm's canal. This cell displays a smooth and flat morphology (Dautriche et al., 2015) and it is distinguished by the presence of Weibel-Palade bodies, specialized organelles that produce, store, and release P-Selectin (Hamanaka et al., 1992). This endothelial cell also exhibits stellate (star-shaped) actin arrangements distributed throughout much of the cell (Ethier et al., 2004). http://purl.obolibrary.org/obo/UBERON_0001549 dorsal metatarsal vein http://purl.obolibrary.org/obo/UBERON_0001638 vein The dorsal metatarsal veins are veins which drain the metatarsus of the foot. [WP,unvetted]. http://purl.obolibrary.org/obo/CL_4033100 atrial intrinsic cardiac ganglion TH neuron http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron A sympathetic neuron that has the soma located in the atrial intrinsic cardiac ganglion and expresses the marker tyrosine hydroxylase (TH). http://purl.obolibrary.org/obo/UBERON_0001550 medial marginal vein http://purl.obolibrary.org/obo/UBERON_0001638 vein A continuation of the Dorsal venous arch of the foot and is the origin of the long saphenous vein. http://purl.obolibrary.org/obo/CL_4033101 superior cervical ganglion TH/DBH neuron http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron A sympathetic neuron that has the soma located in the superior cervical ganglion and expresses the marker tyrosine hydroxylase (TH) and dopamine beta-hydroxylase (DBH). http://purl.obolibrary.org/obo/UBERON_0001552 kidney arcuate artery http://purl.obolibrary.org/obo/UBERON_0003644 kidney arterial blood vessel One of the curved arteries at the corticomedullary border of the kidney that arise from the interlobar arteries and give rise to the interlobular arteries. http://purl.obolibrary.org/obo/CL_4033104 superior cervical ganglion TH/NPY neuron http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron A sympathetic neuron that has the soma located in the superior cervical ganglion and expresses the marker tyrosine hydroxylase (TH) and neuropeptide Y (NPY). http://purl.obolibrary.org/obo/UBERON_0001554 skin of hip http://purl.obolibrary.org/obo/UBERON_0000014 zone of skin A zone of skin that is part of a hip region. http://purl.obolibrary.org/obo/CL_4033106 superior cervical ganglion VIP neuron http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron A sympathetic neuron that has the soma located in the superior cervical ganglion and expresses the marker vasoactive intestinal peptide (VIP). http://purl.obolibrary.org/obo/UBERON_0001555 digestive tract http://purl.obolibrary.org/obo/UBERON_0000025 tube A tube extending from the mouth to the anus. http://purl.obolibrary.org/obo/CL_4033107 superior cervical ganglion CGRP neuron http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron A sympathetic neuron that has the soma located in the superior cervical ganglion and expresses the marker calcitonin gene-related peptide (CGRP). http://purl.obolibrary.org/obo/UBERON_0001556 lower urinary tract http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision Subdivision of urinary system which consists of the urinary bladder and the urethra. http://purl.obolibrary.org/obo/CL_4033108 middle cervical ganglion DBH neuron http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron A sympathetic neuron that has the soma located in the middle cervical ganglion and expresses the marker dopamine beta-hydroxylase (DBH). http://purl.obolibrary.org/obo/UBERON_0001567 cheek http://purl.obolibrary.org/obo/UBERON_0034929 external soft tissue zone A fleshy subdivision of one side of the face bounded by an eye, ear and the nose. http://purl.obolibrary.org/obo/CL_4033109 middle cervical ganglion TH neuron http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron A sympathetic neuron that has the soma located in the middle cervical ganglion and expresses the marker tyrosine hydroxylase (TH). http://purl.obolibrary.org/obo/UBERON_0001568 muscle of larynx http://purl.obolibrary.org/obo/UBERON_0003831 respiratory system muscle The muscles associated with the larynx. http://purl.obolibrary.org/obo/CL_4033110 middle cervical ganglion TH/NPY neuron http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron A sympathetic neuron that has the soma located in the middle cervical ganglion and expresses the marker tyrosine hydroxylase (TH) and neuropeptide Y (NPY). http://purl.obolibrary.org/obo/UBERON_0001571 genioglossus muscle http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure Either of a pair of lingual muscles with origin in the mandible, with insertion to the lingual fascia below the mucous membrane and epiglottis, with nerve supply from the hypoglossal nerve, and whose action depresses and protrudes the tongue. http://purl.obolibrary.org/obo/CL_4033111 middle cervical ganglion NPY neuron http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron A sympathetic neuron that has the soma located in the middle cervical ganglion and expresses the marker neuropeptide Y (NPY). http://purl.obolibrary.org/obo/UBERON_0001572 hyoglossus muscle http://purl.obolibrary.org/obo/UBERON_0001575 extrinsic muscle of tongue A muscle that attaches to the hyopid bone and to the tongue and is innervated by cranial nerve XII. http://purl.obolibrary.org/obo/CL_4033112 middle cervical ganglion VIP neuron http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron A sympathetic neuron that has the soma located in the middle cervical ganglion and expresses the marker vasoactive intestinal peptide (VIP). http://purl.obolibrary.org/obo/UBERON_0001575 extrinsic muscle of tongue http://purl.obolibrary.org/obo/UBERON_0000378 tongue muscle A muscle organ that attaches the tongue to some other structure. http://purl.obolibrary.org/obo/CL_4033113 cervicothoracic ganglion enkephalin neuron http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron A sympathetic neuron that has the soma located in the cervicothoracic ganglion and expresses the marker enkephalin. http://purl.obolibrary.org/obo/UBERON_0001576 intrinsic muscle of tongue http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure The intrinsic tongue muscles are an integral part of the tongue and completely contained within the tongue that are innervated by Cranial Nerve XII. http://purl.obolibrary.org/obo/CL_4033114 cervicothoracic ganglion TH neuron http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron A sympathetic neuron that has the soma located in the cervicothoracic ganglion and expresses the marker tyrosine hydroxylase (TH). http://purl.obolibrary.org/obo/UBERON_0001577 facial muscle http://purl.obolibrary.org/obo/UBERON_0015789 cranial or facial muscle A muscle innervated by a facial nerve. http://purl.obolibrary.org/obo/CL_4033115 cervicothoracic ganglion TH/NPY neuron http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron A sympathetic neuron that has the soma located in the cervicothoracic ganglion and expresses the marker tyrosine hydroxylase (TH) and neuropeptide Y (NPY). http://purl.obolibrary.org/obo/UBERON_0001584 left subclavian artery http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure The subclavian artery that supplies the left pectoral appendage. http://purl.obolibrary.org/obo/CL_4033116 cervicothoracic ganglion VIP neuron http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron A sympathetic neuron that has the soma located in the cervicothoracic ganglion and expresses the marker vasoactive intestinal peptide (VIP). http://purl.obolibrary.org/obo/UBERON_0001586 internal jugular vein http://purl.obolibrary.org/obo/UBERON_0004711 jugular vein One of two jugular veins that collect the blood from the brain, the superficial parts of the face, and the neck. [WP,unvetted]. http://purl.obolibrary.org/obo/CL_4033117 cervicothoracic ganglion VAChT neuron http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron A sympathetic neuron that has the soma located in the cervicothoracic ganglion and expresses the marker vesicular acetylcholine transporter (VAChT). http://purl.obolibrary.org/obo/UBERON_0001587 subclavian vein http://purl.obolibrary.org/obo/UBERON_0001638 vein The subclavian vein is a paired large vein, one on either side of the body. Their diameter is approximately that of the smallest finger. http://purl.obolibrary.org/obo/CL_4033118 thoracic ganglion enkephalin neuron http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron A sympathetic neuron that has the soma located in the thoracic ganglion and expresses the marker enkephalin. http://purl.obolibrary.org/obo/UBERON_0001591 thymic vein http://purl.obolibrary.org/obo/UBERON_0001638 vein A vein that drains blood from the thymus. http://purl.obolibrary.org/obo/UBERON_0001592 bronchial vein http://purl.obolibrary.org/obo/UBERON_0001638 vein The bronchial veins are small vessels that return blood from the larger bronchi and structures at the roots of the lungs. The right side drains into the azygos vein, while the left side drains into the left superior intercostal vein or the accessory hemiazygos vein. The bronchial veins are counterparts to the bronchial arteries. The veins, however, do not return all of the blood supplied by the arteries; much of the blood that is carried in the bronchial arteries is returned to the heart via the pulmonary veins. [WP,unvetted]. http://purl.obolibrary.org/obo/CL_4033119 thoracic ganglion TH neuron http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron A sympathetic neuron that has the soma located in the thoracic ganglion and expresses the marker tyrosine hydroxylase (TH). http://purl.obolibrary.org/obo/UBERON_0001593 venous plexus http://purl.obolibrary.org/obo/UBERON_0005629 vascular plexus A congregation of multiple veins. http://purl.obolibrary.org/obo/CL_4033120 thoracic ganglion TH/NPY neuron http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron A sympathetic neuron that has the soma located in the thoracic ganglion and expresses the marker tyrosine hydroxylase (TH) and neuropeptide Y (NPY). http://purl.obolibrary.org/obo/UBERON_0001605 ciliary muscle http://purl.obolibrary.org/obo/UBERON_0011222 intra-ocular muscle The ciliary muscle is a ring of smooth muscle in the middle layer of the eye that controls the eye's accommodation for viewing objects at varying distances and regulates the flow of aqueous humour through Schlemm's canal. [WP,unvetted]. http://purl.obolibrary.org/obo/CL_4033121 lumbar ganglion VIP neuron http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron A sympathetic neuron that has the soma located in the lumbar ganglion and expresses the marker vasoactive intestinal peptide (VIP). http://purl.obolibrary.org/obo/UBERON_0001607 sphincter pupillae http://purl.obolibrary.org/obo/UBERON_0007521 smooth muscle sphincter A sphincter muscle that is part of the iris. http://purl.obolibrary.org/obo/CL_4033122 lumbar ganglion SST/TH neuron http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron A sympathetic neuron that has the soma located in the lumbar ganglion and expresses the marker somatostatin (SST) and tyrosine hydroxylase (TH). http://purl.obolibrary.org/obo/UBERON_0001608 dilatator pupillae http://purl.obolibrary.org/obo/UBERON_0004234 iris smooth muscle A smooth muscle of the eye, running radially in the iris that functions as a dilator. [WP,unvetted]. http://purl.obolibrary.org/obo/CL_4033123 lumbar ganglion TH/NPY neuron http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron A sympathetic neuron that has the soma located in the lumbar ganglion and expresses the marker tyrosine hydroxylase (TH) and neuropeptide Y (NPY). http://purl.obolibrary.org/obo/UBERON_0001610 lingual artery http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure The lingual artery arises from the external carotid between the superior thyroid and facial artery[WP]. http://purl.obolibrary.org/obo/CL_4033124 lumbar ganglion TH neuron http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron A sympathetic neuron that has the soma located in the lumbar ganglion and expresses the marker tyrosine hydroxylase (TH). http://purl.obolibrary.org/obo/UBERON_0001611 sublingual artery http://purl.obolibrary.org/obo/UBERON_0001637 artery A branch of the lingual artery that supplies the sublingual gland. http://purl.obolibrary.org/obo/CL_4033125 lumbar ganglion NPY neuron http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron A sympathetic neuron that has the soma located in the lumbar ganglion and expresses the marker neuropeptide Y (NPY). http://purl.obolibrary.org/obo/UBERON_0001612 facial artery http://purl.obolibrary.org/obo/UBERON_0035398 branch of external carotid artery A branch of the external carotid artery that supplies structures of the face. [WP,unvetted]. http://purl.obolibrary.org/obo/CL_4033127 lower airway ganglion ChAT/VIP neuron http://purl.obolibrary.org/obo/CL_0011102 parasympathetic neuron A parasympathetic neuron that has the soma located in the lower airway ganglion and expresses the marker choline O-acetyltransferase (ChAT) and vasoactive intestinal peptide (VIP). http://purl.obolibrary.org/obo/UBERON_0001613 occipital artery http://purl.obolibrary.org/obo/UBERON_0035398 branch of external carotid artery The occipital artery arises opposite the facial artery, its path is below the posterior belly of digastric to the occipital region. This artery supplies blood to the back of the scalp and sterno-mastoid muscles. Other muscles it supplies are deep muscles in the back and neck. [WP,unvetted]. http://purl.obolibrary.org/obo/CL_4033128 celiac ganglion VIP neuron http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron A sympathetic neuron that has the soma located in the celiac ganglion and expresses the marker vasoactive intestinal peptide (VIP). http://purl.obolibrary.org/obo/UBERON_0001616 maxillary artery http://purl.obolibrary.org/obo/UBERON_0001637 artery An artery that supplies deep structures of the face. It comes just out behind the neck of the mandible. [WP,unvetted]. http://purl.obolibrary.org/obo/CL_4033129 celiac ganglion PHI neuron http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron A sympathetic neuron that has the soma located in the celiac ganglion and expresses the marker peptide histidine isoleucine (PHI). http://purl.obolibrary.org/obo/UBERON_0001619 ophthalmic artery http://purl.obolibrary.org/obo/UBERON_0001637 artery The ophthalmic artery is a branch of the internal carotid artery which supplies branches to supply the eye and other structures in the orbit. It enters the orbit together with the Optic nerve through the Optic foramen/canal. [WP,modified]. http://purl.obolibrary.org/obo/CL_4033130 celiac ganglion CGRP neuron http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron A sympathetic neuron that has the soma located in the celiac ganglion and expresses the marker calcitonin gene-related peptide (CGRP). http://purl.obolibrary.org/obo/UBERON_0001622 lacrimal artery http://purl.obolibrary.org/obo/UBERON_0001637 artery The lacrimal artery arises close to the optic foramen, and is one of the largest branches derived from the ophthalmic artery: not infrequently it is given off before the artery enters the orbit. It accompanies the lacrimal nerve along the upper border of the Lateral Rectus, supplies the lacrimal gland. [WP,unvetted]. http://purl.obolibrary.org/obo/CL_4033131 celiac ganglion SP neuron http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron A sympathetic neuron that has the soma located in the celiac ganglion and expresses the marker substance P (SP). http://purl.obolibrary.org/obo/UBERON_0001628 posterior communicating artery http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure One of a pair of right-sided and left-sided blood vessels in the circle of Willis. It connects the three cerebral arteries of the same side. Anteriorly, it is one portion of the terminal trifurcation of the internal carotid artery. The anterior cerebral artery and the middle cerebral artery are the other two branches of the trifurcation. Posteriorly, it communicates with the posterior cerebral artery. http://purl.obolibrary.org/obo/CL_4033132 celiac ganglion SOM neuron http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron A sympathetic neuron that has the soma located in the celiac ganglion and expresses the marker somatostatin (SOM). http://purl.obolibrary.org/obo/UBERON_0001630 muscle organ http://purl.obolibrary.org/obo/UBERON_0005090 muscle structure Organ consisting of a tissue made up of various elongated cells that are specialized to contract and thus to produce movement and mechanical work[GO]. http://purl.obolibrary.org/obo/CL_4033133 celiac ganglion SOM/CGRP neuron http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron A sympathetic neuron that has the soma located in the celiac ganglion and expresses the marker somatostatin (SOM) and calcitonin gene-related peptide (CGRP). http://purl.obolibrary.org/obo/UBERON_0001639 hepatic portal vein http://purl.obolibrary.org/obo/UBERON_0002017 portal vein A portal vein that transports nutrients from the digestive tract to the liver[Kardong]. http://purl.obolibrary.org/obo/CL_4033134 superior mesenteric ganglion SP neuron http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron A sympathetic neuron that has the soma located in the superior mesenteric ganglion and expresses the marker substance P (SP). http://purl.obolibrary.org/obo/UBERON_0001640 celiac artery http://purl.obolibrary.org/obo/UBERON_0012254 abdominal aorta artery The first major branch of the abdominal aorta. http://purl.obolibrary.org/obo/CL_4033135 inferior mesenteric ganglion TH neuron http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron A sympathetic neuron that has the soma located in the inferior mesenteric ganglion and expresses the marker tyrosine hydroxylase (TH). http://purl.obolibrary.org/obo/UBERON_0001651 right pulmonary artery http://purl.obolibrary.org/obo/UBERON_0001637 artery The pulmonary artery that supplies the right lung. http://purl.obolibrary.org/obo/CL_4033137 otic ganglion nNOS neuron http://purl.obolibrary.org/obo/CL_0011102 parasympathetic neuron A parasympathetic neuron that has the soma located in the otic ganglion and expresses the marker neuronal nitric oxide synthase 1 (nNOS). http://purl.obolibrary.org/obo/UBERON_0001652 left pulmonary artery http://purl.obolibrary.org/obo/UBERON_0001637 artery The pulmonary artery that supplies the left lung. http://purl.obolibrary.org/obo/CL_4033138 otic ganglion VIP neuron http://purl.obolibrary.org/obo/CL_0011102 parasympathetic neuron A parasympathetic neuron that has the soma located in the otic ganglion and expresses the marker vasoactive intestinal peptide (VIP). http://purl.obolibrary.org/obo/UBERON_0001653 facial vein http://purl.obolibrary.org/obo/UBERON_0009141 craniocervical region vein The anterior facial vein (facial vein) commences at the side of the root of the nose, and is a direct continuation of the angular vein where it also receives a small nasal branch. It lies behind the facial artery and follows a less tortuous course. It receives blood from the external palatine vein before it either joins the anterior branch of the retromandibular vein to form the common facial vein, or drains directly into the internal jugular vein. [WP,unvetted]. http://purl.obolibrary.org/obo/CL_4033139 ciliary ganglion VIP/PHI neuron http://purl.obolibrary.org/obo/CL_0011102 parasympathetic neuron A parasympathetic postganglionic neuron whose soma is located in the ciliary ganglion and that co-expresses vasoactive intestinal peptide (VIP) and peptide histidine isoleucine (PHI, both encoded by the VIP gene). This neuron provides parasympathetic innervation to the eye, contributing to regulation of pupillary constriction and ciliary muscle accommodation. It has been identified in human ciliary ganglia by immunohistochemistry (Kiyokawa et al. 2012, PMID:22095632). VIP/PHI co-expression distinguishes this subpopulation from other cholinergic parasympathetic neurons in the ciliary ganglion and is characteristic of a subset of cranial parasympathetic neurons in humans and other mammals. http://purl.obolibrary.org/obo/UBERON_0001663 cerebral vein http://purl.obolibrary.org/obo/UBERON_0003499 brain blood vessel The cerebral veins are divisible into external and internal groups according to the outer surfaces or the inner parts of the hemispheres they drain into. The external veins are the superior cerebral veins, inferior cerebral veins, and middle cerebral vein. [WP,unvetted]. http://purl.obolibrary.org/obo/CL_4033140 ciliary ganglion TH neuron http://purl.obolibrary.org/obo/CL_0011102 parasympathetic neuron A parasympathetic neuron that has the soma located in the ciliary ganglion and expresses the marker tyrosine hydroxylase (TH). http://purl.obolibrary.org/obo/UBERON_0001668 cerebellar vein http://purl.obolibrary.org/obo/UBERON_0001638 vein A vein that drains the cerebellum. http://purl.obolibrary.org/obo/CL_4033141 submandibular ganglion TH cholinergic neuron http://purl.obolibrary.org/obo/CL_0011102 parasympathetic neuron A parasympathetic neuron that has the soma located in the submandibular ganglion and expresses the marker tyrosine hydroxylase (TH). http://purl.obolibrary.org/obo/UBERON_0001675 trigeminal ganglion http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure The cranial ganglion that is associated with and extends fibers into the trigeminal nerve. http://purl.obolibrary.org/obo/CL_4033142 submandibular ganglion VIP/PHI neuron http://purl.obolibrary.org/obo/CL_0011102 parasympathetic neuron A parasympathetic neuron that has the soma located in the submandibular ganglion and expresses the marker vasoactive intestinal peptide (VIP) and peptide histidine isoleucine (PHI). http://purl.obolibrary.org/obo/UBERON_0001676 occipital bone http://purl.obolibrary.org/obo/UBERON_0011164 neurocranium bone The bone at the lower, posterior part of the skull. http://purl.obolibrary.org/obo/CL_4033143 submandibular ganglion nNOS neuron http://purl.obolibrary.org/obo/CL_0011102 parasympathetic neuron A parasympathetic neuron that has the soma located in the submandibular ganglion and expresses the marker neuronal nitric oxide synthase 1 (nNOS). http://purl.obolibrary.org/obo/UBERON_0001678 temporal bone http://purl.obolibrary.org/obo/UBERON_0008193 pneumatized bone The large, irregular bone located at the base and side of the skull; consists of three parts at birth: squamous, tympanic, and petrous. http://purl.obolibrary.org/obo/CL_4033144 pterygopalatine ganglion VIP/PHI neuron http://purl.obolibrary.org/obo/CL_0011102 parasympathetic neuron A parasympathetic neuron that has the soma located in the pterygopalatine ganglion and expresses the marker vasoactive intestinal peptide (VIP) and peptide histidine isoleucine (PHI). http://purl.obolibrary.org/obo/UBERON_0001685 hyoid bone http://purl.obolibrary.org/obo/UBERON_0008001 irregular bone A horseshoe shaped bone situated in the anterior midline of the neck between the chin and the thyroid cartilage. The hyoid bone provides attachment to the muscles of the floor of the mouth and the tongue above, the larynx below, and the epiglottis and pharynx behind. [WP,modified]. http://purl.obolibrary.org/obo/CL_4033145 pterygopalatine ganglion VIP neuron http://purl.obolibrary.org/obo/CL_0011102 parasympathetic neuron A parasympathetic neuron that has the soma located in the pterygopalatine ganglion and expresses the marker vasoactive intestinal peptide (VIP). http://purl.obolibrary.org/obo/UBERON_0001686 auditory ossicle bone http://purl.obolibrary.org/obo/UBERON_0003457 head bone One of 3 small bones contained within the middle ear space and serve to transmit sounds from the air to the fluid-filled labyrinth. The absence of the auditory ossicles would constitute a moderate-to-severe hearing loss. The term 'ossicles' literally means 'tiny bones' and commonly refers to the auditory ossicles, though the term may refer to any small bone throughout the body. [WP,unvetted]. http://purl.obolibrary.org/obo/CL_4033146 pterygopalatine ganglion nNOS neuron http://purl.obolibrary.org/obo/CL_0011102 parasympathetic neuron A parasympathetic neuron that has the soma located in the pterygopalatine ganglion and expresses the marker neuronal nitric oxide synthase 1 (nNOS). http://purl.obolibrary.org/obo/UBERON_0001690 ear http://purl.obolibrary.org/obo/UBERON_0010314 structure with developmental contribution from neural crest Sense organ in vertebrates that is specialized for the detection of sound, and the maintenance of balance. Includes the outer ear and middle ear, which collect and transmit sound waves; and the inner ear, which contains the organs of balance and (except in fish) hearing. Also includes the pinna, the visible part of the outer ear, present in some mammals. http://purl.obolibrary.org/obo/CL_4033147 vestibular ganglion SP neuron http://purl.obolibrary.org/obo/CL_0000101 sensory neuron A sensory neuron that has the soma located in the vestibular ganglion and expresses the marker substance P (SP). http://purl.obolibrary.org/obo/UBERON_0001694 petrous part of temporal bone http://purl.obolibrary.org/obo/UBERON_0005913 zone of bone organ The petrous portion of the temporal bone or pyramid is pyramidal and is wedged in at the base of the skull between the sphenoid and occipital bones. Directed medially, forward, and a little upward, it presents for examination a base, an apex, three surfaces, and three angles, and contains, in its interior, the essential parts of the organ of hearing. The petrous portion is among the most basal elements of the skull and forms part of the endocranium.[WP,unvetted]. http://purl.obolibrary.org/obo/CL_4033148 nodose ganglion TRPV1 neuron http://purl.obolibrary.org/obo/CL_0000101 sensory neuron A sensory neuron that has the soma located in the nodose ganglion and expresses the marker transient receptor potential vanilloid 1 (TRPV1). http://purl.obolibrary.org/obo/UBERON_0001697 orbit of skull http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure Subdivision of skeleton that is an anterolateral part of the cranium and structurally supports the eye. Includes bones formed and located in sclerotic layer of eyeball. http://purl.obolibrary.org/obo/CL_4033149 nodose ganglion P2X3 neuron http://purl.obolibrary.org/obo/CL_0000101 sensory neuron A sensory neuron that has the soma located in the nodose ganglion and expresses the marker purinergic receptor P2X3 (P2X3). http://purl.obolibrary.org/obo/UBERON_0001700 geniculate ganglion http://purl.obolibrary.org/obo/UBERON_0010313 neural crest-derived structure The group of sensory neuron cell bodies associated with the facial nerve (seventh cranial nerve). http://purl.obolibrary.org/obo/CL_4033153 jugular ganglion TRPV2 neuron http://purl.obolibrary.org/obo/CL_0000101 sensory neuron A sensory neuron that has the soma located in the jugular ganglion and expresses the marker transient receptor potential vanilloid 2 (TRPV2). http://purl.obolibrary.org/obo/UBERON_0001701 glossopharyngeal ganglion http://purl.obolibrary.org/obo/UBERON_0009127 epibranchial ganglion The group of neuron cell bodies associated with the ninth cranial nerve. http://purl.obolibrary.org/obo/CL_4033154 jugular ganglion SP neuron http://purl.obolibrary.org/obo/CL_0000101 sensory neuron A sensory neuron that has the soma located in the jugular ganglion and expresses the marker substance P (SP). http://purl.obolibrary.org/obo/UBERON_0001703 neurocranium http://purl.obolibrary.org/obo/UBERON_0011158 primary subdivision of skull Subdivision of skeletal system that surrounds and protects the brain. Includes the skull base, sensory capsules and the central part of the skull roof. http://purl.obolibrary.org/obo/CL_4033155 jugular ganglion CGRP neuron http://purl.obolibrary.org/obo/CL_0000101 sensory neuron A sensory neuron that has the soma located in the jugular ganglion and expresses the marker calcitonin gene-related peptide (CGRP). http://purl.obolibrary.org/obo/UBERON_0001709 upper jaw region http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision Subdivision of head that consists of the upper jaw skeletal elements plus associated soft tissue (skin, lips, muscle)[cjm]. http://purl.obolibrary.org/obo/UBERON_0001710 lower jaw region http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision Subdivision of head that consists of the lower jaw skeletal elements plus associated soft tissue (skin, lips, muscle)[cjm]. http://purl.obolibrary.org/obo/CL_4033157 geniculate ganglion TRPV1 neuron http://purl.obolibrary.org/obo/CL_0000101 sensory neuron A sensory neuron that has the soma located in the geniculate ganglion and expresses the marker transient receptor potential vanilloid 1 (TRPV1). http://purl.obolibrary.org/obo/UBERON_0001714 cranial ganglion http://purl.obolibrary.org/obo/UBERON_0000045 ganglion The groups of nerve cell bodies associated with the twelve cranial nerves. http://purl.obolibrary.org/obo/CL_4033158 geniculate ganglion SPARCL1 neuron http://purl.obolibrary.org/obo/CL_0000101 sensory neuron A sensory neuron that has the soma located in the geniculate ganglion and expresses the marker SPARC-like protein 1 (SPARCL1). http://purl.obolibrary.org/obo/UBERON_0001715 oculomotor nuclear complex http://purl.obolibrary.org/obo/UBERON_0019267 gray matter of midbrain Nuclear complex containing subnuclei that give rise to the axons of the occulomotor nerve, both motor and parasympathetic fibers, situated at the midline at the level of the superior colliculus in the midbrain tegmentum (Brodal, Neurological Anatomy, 3rd ed., 1981, pg 533-534). http://purl.obolibrary.org/obo/CL_4033159 geniculate ganglion VGLUT2 neuron http://purl.obolibrary.org/obo/CL_0000101 sensory neuron A sensory neuron that has the soma located in the geniculate ganglion and expresses the marker vesicular glutamate transporter 2 (VGLUT2). http://purl.obolibrary.org/obo/UBERON_0001720 cochlear nucleus http://purl.obolibrary.org/obo/UBERON_0007635 nucleus of medulla oblongata Any of the nuclei of the cochlear nuclear complex. http://purl.obolibrary.org/obo/CL_4033160 myenteric ganglion of small intestine ChAT neuron http://purl.obolibrary.org/obo/CL_0020057 cholinergic neuron of myenteric plexus An enteric neuron that has the soma located in the myenteric ganglion of the small intestine and expresses the marker choline O-acetyltransferase (ChAT). http://purl.obolibrary.org/obo/UBERON_0001725 cranial synchondrosis http://purl.obolibrary.org/obo/UBERON_0002215 synchondrosis The cartilaginous joints of the skull; these include sphenoethmoidal synchondrosis, sphenooccipital synchondrosis, sphenopetrosal synchondrosis, petrooccipital synchondrosis, anterior intraoccipital synchondrosis and posterior intraoccipital synchondrosis. http://purl.obolibrary.org/obo/CL_4033161 myenteric ganglion of small intestine nNOS neuron http://purl.obolibrary.org/obo/CL_0007011 enteric neuron An enteric neuron that has the soma located in the myenteric ganglion of the small intestine and expresses the marker neuronal nitric oxide synthase 1 (nNOS). http://purl.obolibrary.org/obo/UBERON_0001727 taste bud http://purl.obolibrary.org/obo/UBERON_0004119 endoderm-derived structure A specialized receptor organ that is a collection of cells spanning the gustatory epithelium. http://purl.obolibrary.org/obo/CL_4033162 myenteric ganglion of small intestine VIP neuron http://purl.obolibrary.org/obo/CL_0007011 enteric neuron An enteric neuron that has the soma located in the myenteric ganglion of the small intestine and expresses the marker vasoactive intestinal peptide (VIP). http://purl.obolibrary.org/obo/UBERON_0001731 cavity of pharynx http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space An anatomical space that is enclosed by a pharynx. http://purl.obolibrary.org/obo/CL_4033163 myenteric ganglion of small intestine nNOS/VIP neuron http://purl.obolibrary.org/obo/CL_0007011 enteric neuron An enteric neuron that has the soma located in the myenteric ganglion of the small intestine and expresses the marker neuronal nitric oxide synthase 1 (nNOS) and vasoactive intestinal peptide (VIP). http://purl.obolibrary.org/obo/UBERON_0001743 ligament of larynx http://purl.obolibrary.org/obo/UBERON_0008845 nonskeletal ligament A ligament that is part of a larynx and connexts the cartilages of the larynx. http://purl.obolibrary.org/obo/CL_4033164 myenteric ganglion of small intestine nNOS/ChAT neuron http://purl.obolibrary.org/obo/CL_0007011 enteric neuron An enteric neuron that has the soma located in the myenteric ganglion of the small intestine and expresses the marker neuronal nitric oxide synthase 1 (nNOS) and choline O-acetyltransferase (ChAT). http://purl.obolibrary.org/obo/UBERON_0001744 lymphoid tissue http://purl.obolibrary.org/obo/UBERON_0034769 lymphomyeloid tissue Portion of connective tissue with various types of white blood cells enmeshed in it, most numerous being the lymphocytes[WP]. http://purl.obolibrary.org/obo/CL_4033165 myenteric ganglion of small intestine ChAT/CALR/SOM/SP neuron http://purl.obolibrary.org/obo/CL_0007011 enteric neuron An enteric neuron that has the soma located in the myenteric ganglion of the small intestine and expresses the marker choline acetyltransferase (ChAT), calretinin (CALR), somatostatin (SOM), and substance P (SP). http://purl.obolibrary.org/obo/UBERON_0001745 secondary nodular lymphoid tissue http://purl.obolibrary.org/obo/UBERON_0000444 lymphoid follicle A lymphoid follicle that contains a germinal center. http://purl.obolibrary.org/obo/CL_4033166 myenteric ganglion of small intestine VIP/GAL neuron http://purl.obolibrary.org/obo/CL_0007011 enteric neuron An enteric neuron that has the soma located in the myenteric ganglion of the small intestine and expresses the marker vasoactive intestinal peptide (VIP) and galanin (GAL). http://purl.obolibrary.org/obo/UBERON_0001747 parenchyma of thyroid gland http://purl.obolibrary.org/obo/UBERON_0000353 parenchyma A parenchyma that is part of a thyroid follicle [Automatically generated definition]. http://purl.obolibrary.org/obo/CL_4033167 pelvic ganglion TH neuron http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron A sympathetic neuron that has the soma located in the pelvic ganglion and expresses the marker tyrosine hydroxylase (TH). http://purl.obolibrary.org/obo/UBERON_0001748 capsule of parathyroid gland http://purl.obolibrary.org/obo/UBERON_0003893 capsule The dense and irregular connective tissue capsule surrounding a parathyroid gland. http://purl.obolibrary.org/obo/CL_4033168 pelvic ganglion TH/DBH neuron http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron A sympathetic neuron that has the soma located in the pelvic ganglion and expresses the marker tyrosine hydroxylase (TH) and dopamine beta-hydroxylase (DBH). http://purl.obolibrary.org/obo/UBERON_0001749 parenchyma of parathyroid gland http://purl.obolibrary.org/obo/UBERON_0000353 parenchyma A parenchyma that is part of a parathyroid gland [Automatically generated definition]. http://purl.obolibrary.org/obo/CL_4033169 pelvic ganglion VAChT neuron http://purl.obolibrary.org/obo/CL_0011102 parasympathetic neuron A parasympathetic neuron that has the soma located in the pelvic ganglion and expresses the marker vesicular acetylcholine transporter (VAChT). http://purl.obolibrary.org/obo/UBERON_0001751 dentine http://purl.obolibrary.org/obo/UBERON_4000013 mineralized skeletal tissue Collagen-rich odontogenic tissue characteristic of teeth and tooth-like skeletal elements (e.g., odontodes); mature dentine is mineralized and develops from predentine tissue; often (but not always) tubular and acellular. http://purl.obolibrary.org/obo/CL_4033170 pelvic ganglion nNOS neuron http://purl.obolibrary.org/obo/CL_0011102 parasympathetic neuron A parasympathetic neuron that has the soma located in the pelvic ganglion and expresses the marker neuronal nitric oxide synthase 1 (nNOS). http://purl.obolibrary.org/obo/UBERON_0001752 enamel http://purl.obolibrary.org/obo/UBERON_4000013 mineralized skeletal tissue A dentine-like hypermineralized substance that covers the tooth tip. Enamel's primary mineral is hydroxylapatite, which is a crystalline calcium phosphate. Unlike dentin and bone, enamel does not contain collagen. Instead, it has two unique classes of proteins called amelogenins and enamelins[WP]. http://purl.obolibrary.org/obo/CL_4033171 pelvic ganglion nNOS/VIP neuron http://purl.obolibrary.org/obo/CL_0011102 parasympathetic neuron A parasympathetic neuron that has the soma located in the pelvic ganglion and expresses the marker neuronal nitric oxide synthase (nNOS) 1 and vasoactive intestinal peptide (VIP). http://purl.obolibrary.org/obo/UBERON_0001753 cementum http://purl.obolibrary.org/obo/UBERON_0010365 odontoid tissue Odontoid tissue that is deposited by cementoblasts onto dentine tissue and functions to attach teeth, odontodes and other odontogenic derivatives to bone tissue and the integument. http://purl.obolibrary.org/obo/CL_4033172 pelvic ganglion NPY/VAChT neuron http://purl.obolibrary.org/obo/CL_0011102 parasympathetic neuron A parasympathetic neuron that has the soma located in the pelvic ganglion and expresses the marker neuropeptide Y (NPY) and vesicular acetylcholine transporter (VAChT). http://purl.obolibrary.org/obo/UBERON_0001758 periodontium http://purl.obolibrary.org/obo/UBERON_0000479 tissue The tissues that invest or help to invest and support the teeth, including the periodontal ligament, gingivae, cementum, and alveolar and supporting bone[BTO]. http://purl.obolibrary.org/obo/CL_4033173 pelvic ganglion nNOS/VAChT neuron http://purl.obolibrary.org/obo/CL_0011102 parasympathetic neuron A parasympathetic neuron that has the soma located in the pelvic ganglion and expresses the marker neuronal nitric oxide synthase 1(nNOS) and vesicular acetylcholine transporter (VAChT). http://purl.obolibrary.org/obo/UBERON_0001763 odontogenic papilla http://purl.obolibrary.org/obo/UBERON_0007213 mesenchyme derived from head neural crest A condensation of odontoblasts that forms the part of a tooth germ that gives rise to dentin and pulp in the mature tooth. It lies below a cellular aggregation known as the enamel organ. http://purl.obolibrary.org/obo/CL_4033174 ovarian nerve plexus ganglion TH neuron http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron A sympathetic neuron that has the soma located in the ovarian nerve plexus ganglion and expresses the marker tyrosine hydroxylase (TH). http://purl.obolibrary.org/obo/UBERON_0001765 mammary duct http://purl.obolibrary.org/obo/UBERON_0003914 epithelial tube Epithelial tube that transports milk[GO]. http://purl.obolibrary.org/obo/CL_4052062 onychofibroblast http://purl.obolibrary.org/obo/CL_0002620 skin fibroblast A specialized fibroblast located in the onychodermis that play a key role in nail growth and regeneration by interacting with LGR6-positive nail matrix keratinocytes. These interactions mediate essential signaling pathways, particularly WNT signaling, which is critical for epithelial–mesenchymal communication and coordinated nail development. In humans, this cell expresses key markers, including RSPO4, MSX1, WIF1, and BMP5, all involved in nail differentiation. http://purl.obolibrary.org/obo/UBERON_0001766 anterior chamber of eyeball http://purl.obolibrary.org/obo/UBERON_0006311 chamber of eyeball The space in the eye, filled with aqueous humor, and bounded anteriorly by the cornea and a small portion of the sclera and posteriorly by a small portion of the ciliary body, the iris, and part of the crystalline lens. http://purl.obolibrary.org/obo/CL_4052063 nail bed keratinocyte http://purl.obolibrary.org/obo/CL_4052061 epidermal keratinocyte A keratinocyte that resides in the nail bed, responsible for tightly attaching the nail plate to the underlying dermis. Unlike typical epidermal keratinocytes, it exhibits limited proliferation, undergoes modified differentiation that skips the granular layer and conventional cornification, and primarily ensures adhesion and maintenance of the nail plate. In humans, this cell expresses characteristic markers, including the protease inhibitor SPINK6 and the differentiation-associated protein KRT16. http://purl.obolibrary.org/obo/UBERON_0001770 lacrimal canaliculus http://purl.obolibrary.org/obo/UBERON_0004111 anatomical conduit The part of the lacrimal duct that connects the lacrimal punctum to the lacrimal sac. http://purl.obolibrary.org/obo/CL_4052064 nail matrix keratinocyte http://purl.obolibrary.org/obo/CL_4052061 epidermal keratinocyte A keratinocyte that is part of the nail matrix epithelium, distinguished by its high proliferative capacity and its role in nail plate formation via onychokeratinization, a differentiation process that uniquely bypasses the formation of a granular layer, resulting in the production of hard, compact keratin. Unlike skin epidermal keratinocytes, this cell expresses a distinctive mix of hard (hair-type) and select epidermal keratins (Kitahara and Ogawa, 1993). In humans, LGR6 and WNT6 are enriched in the basal compartment, with LGR6 marking nail stem cells in both mice and humans, and exhibiting strong expression in the human proximal nail matrix (Kim et al., 2021). http://purl.obolibrary.org/obo/UBERON_0001772 corneal epithelium http://purl.obolibrary.org/obo/UBERON_0015808 eye epithelium The smooth stratified squamous epithelium that covers the outer surface of the cornea. http://purl.obolibrary.org/obo/CL_4052065 serous acinar cell of salivary gland http://purl.obolibrary.org/obo/CL_0020059 serous demilune cell of salivary gland An acinar cell of the salivary gland, characterized by a pyramidal or triangular shape with a spherical nucleus and abundant eosinophilic zymogen granules. This cell secretes watery, enzyme‐rich fluid containing α-amylase, proline-rich proteins, and secretory immunoglobulins for starch digestion and antimicrobial defence. In humans and mice, serous acinar cell predominates in the parotid gland and to a lesser extent in the submandibular gland, where it exists alongside mucous acinar cells (Maruyama et al., 2019). http://purl.obolibrary.org/obo/CL_4052066 mucous acinar cell of salivary gland http://purl.obolibrary.org/obo/CL_0002623 acinar cell of salivary gland An acinar cell of the salivary gland, responsible for producing a viscous, mucin‐rich solution, thereby facilitating lubrication and protection of the oral mucosa. This cell is characterized by an elongated shape, clear cytoplasm filled with mucin granules, and a basally compressed nucleus (Barrows et al., 2020). In humans and mice, the mucous acinar cell predominates in the sublingual gland and minor salivary glands, while also being present in mixed glands such as the submandibular gland, where it coexists with serous acinar cells (Maruyama et al., 2019). http://purl.obolibrary.org/obo/CL_4052067 seromucous acinar cell of salivary gland http://purl.obolibrary.org/obo/CL_0002623 acinar cell of salivary gland An acinar cell of the salivary gland, with a hybrid seromucous phenotype, co-expressing serous and mucous markers and producing a mixed secretion of enzymes-containing serous fluid and mucins essential for lubrication, digestion, and antimicrobial defense. Predominant in the submandibular glands of humans and mice, its differentiation and secretory gene expression are regulated by FGFR2b–MAPK signaling, driven by paracrine FGF7 from adjacent myoepithelial cells, which provides a key niche signal for seromucous identity. http://purl.obolibrary.org/obo/CL_4052069 excretory duct cell of salivary gland http://purl.obolibrary.org/obo/CL_1001596 salivary gland glandular cell A duct epithelial cell that is part of the excretory duct of the salivary gland, which transports saliva from the intralobular ductal system to the oral cavity. While primarily serving as a conduit, this cell may play a role in the saliva modification, contributing to its hypotonicity. In humans, this cell has a pseudostratified columnar shape. http://purl.obolibrary.org/obo/CL_4052070 dual-feature fallopian tube progenitor cell http://purl.obolibrary.org/obo/CL_0011026 progenitor cell A bipotent progenitor cell within the human fallopian tube epithelium, characterized by the concurrent expression of epithelial (e.g., EpCAM/CD326) and endothelial (e.g., PECAM1/CD31) markers at both the cell surface and transcript levels. This cell has the capacity to differentiate into ciliated and secretory epithelial cells, as well as potentially endothelial/stromal lineages. Positioned at the apex of lineage bifurcation, the cell exhibits stem-like and endothelial features, representing an intermediate developmental state between undifferentiated progenitors and lineage-committed epithelial cells. http://purl.obolibrary.org/obo/CL_4052071 quiescent fibroblast http://purl.obolibrary.org/obo/CL_0000057 fibroblast A fibroblast in a quiescent state, characterized by a smaller, spindle-shaped morphology with a relatively small cytoplasm, modest rough endoplasmic reticulum and condensed chromatin. Despite low proliferation and contractility, it maintains high metabolic activity for extracellular-matrix homeostasis through continuous matrix protein turnover and mechanosensitive signaling. This cell can rapidly differentiate into contractile myofibroblasts under injury or inflammatory cues to drive tissue repair. http://purl.obolibrary.org/obo/CL_4072006 A9 dopaminergic neuron http://purl.obolibrary.org/obo/CL_0008060 GABA-Glut neuron A type of dopaminergic neuron in the substantia nigra involved in motor control and particularly vulnerable in Parkinson’s disease. In mice, it is notable for its heterogeneous co-release of dopamine with either glutamate or GABA. It releases GABA through alternative synthesis pathways or reuptake mechanisms independent of GAD expression. http://purl.obolibrary.org/obo/UBERON_0001773 sclera http://purl.obolibrary.org/obo/UBERON_0000064 organ part Opaque fibrous outer layer of the eyeball[ZFA,Kardong,WP]. http://purl.obolibrary.org/obo/CL_4072014 tanycyte of vascular organ of lamina terminalis http://purl.obolibrary.org/obo/CL_2000030 hypothalamus cell A specialized, non-ciliated ependymal glial cell located in the ventricular wall of the organum vasculosum of the lamina terminalis (OVLT) and characterized by elongated basal processes extending into the parenchyma to contact fenestrated capillaries. In mice, it is characterised by the expression of tight junction proteins (claudin 1, occludin, ZO-1) forming a continuous honeycomb junctional pattern. This cell contributes to a functional blood–cerebrospinal fluid (CSF) barrier at the ventricular interface of the OVLT. http://purl.obolibrary.org/obo/UBERON_0001774 skeletal muscle of trunk http://purl.obolibrary.org/obo/UBERON_0014892 skeletal muscle organ, vertebrate A skeletal muscle organ that is part of the trunk region. http://purl.obolibrary.org/obo/UBERON_0001777 substantia propria of cornea http://purl.obolibrary.org/obo/UBERON_0003891 stroma The lamellated connective tissue of the cornea between the Bowman and Descemet membranes. http://purl.obolibrary.org/obo/CL_4072015 monocyte-derived Kupffer cell http://purl.obolibrary.org/obo/CL_0000091 Kupffer cell A Kupffer cell located within the hepatic sinusoids, derived from circulating bone marrow monocytes that acquire the phenotypic markers and functional properties of resident Kupffer cells through niche-dependent imprinting, typically following depletion of the embryonically derived Kupffer cell population. During liver injury, MoKCs become the dominant Kupffer cell subset, exhibiting enhanced proliferation, resistance to apoptosis, and key roles in tissue repair and fibrosis attenuation. http://purl.obolibrary.org/obo/UBERON_0001778 ciliary epithelium http://purl.obolibrary.org/obo/UBERON_0015808 eye epithelium A double layer covering the ciliary body that produces aqueous humor. http://purl.obolibrary.org/obo/CL_4072016 NPY interneuron http://purl.obolibrary.org/obo/CL_0011005 GABAergic interneuron An interneuron that expresses neuropeptide Y (NPY) and is mainly located in cortical layers II–III and VI, as well as in various brain regions such as the medial geniculate and inferior colliculus. The NPY cell population is physiologically diverse, displaying a range of firing behaviors, including adapting, fast-spiking, and accelerating patterns. http://purl.obolibrary.org/obo/UBERON_0001779 iris stroma http://purl.obolibrary.org/obo/UBERON_0003891 stroma The delicate vascular connective tissue that lies between the anterior surface of the iris and the pars iridica retinae. http://purl.obolibrary.org/obo/CL_4072017 agouti-related protein expressing neuron http://purl.obolibrary.org/obo/CL_0012001 neuron of the forebrain A GABAergic neuron located in the arcuate nucleus of the hypothalamus that expresses agouti-related protein (AgRP). This neuron can coexpress AgRP, GABA, and neuropeptide Y (NPY) in mice, and plays a key role in integrating metabolic signals. It is activated by hunger-related hormones such as ghrelin and inhibited by satiety signals like leptin. http://purl.obolibrary.org/obo/CL_4072018 pacemaker neuron http://purl.obolibrary.org/obo/CL_0000540 neuron A neuron that generates rhythmic bursts of action potentials independently of synaptic input. This intrinsic property enables it to maintain oscillatory activity even when isolated from other neurons. It populates the brainstem, hypothalamus, basal ganglia, spinal cord, and cerebellum. It plays a crucial role in regulating circadian rhythms in the suprachiasmatic nucleus, generating respiratory rhythms in the preBötzinger complex, and synchronizing neural networks. http://purl.obolibrary.org/obo/CL_4072019 SCN pacemaker neuron http://purl.obolibrary.org/obo/CL_0012001 neuron of the forebrain A type of neuron located in the suprachiasmatic nucleus (SCN) that possesses intrinsic circadian rhythmicity, characterized by strong and rhythmic expression of core clock genes and the ability to independently generate and sustain circadian oscillations. In mice, the specific subtypes Avp+/Nms+, Vip+/Nms+, and Cck+/C1ql3+ neurons have the most robust circadian gene expression and contribute to synchronizing and maintaining rhythmicity within the SCN network (Wen et al., 2020). http://purl.obolibrary.org/obo/CL_4072021 corticotropin-releasing neuron http://purl.obolibrary.org/obo/CL_0000467 adrenocorticotropic hormone secreting cell A specialised type of interneuron defined by the secretion of corticotropin-releasing hormone (CRH), a key peptide in activating the hypothalamic–pituitary–adrenal (HPA) axis during stress. It is primarily located in the paraventricular nucleus (PVN) of the hypothalamus, with additional presence in the hippocampus, piriform area, central amygdalar nucleus, Barrington’s nucleus, and inferior olivary complex (Peng et al., 2017). http://purl.obolibrary.org/obo/UBERON_0001780 spinal nerve http://purl.obolibrary.org/obo/UBERON_0001021 nerve The any of the paired peripheral nerves formed by the union of the dorsal and ventral spinal roots from each spinal cord segment[MP,modified]. http://purl.obolibrary.org/obo/CL_4072022 Lamp5 Lhx6 GABAergic interneuron (Homo sapiens) http://purl.obolibrary.org/obo/CL_4042013 Lamp5 Lhx6 neuron A Lamp5 Lhx6 GABAergic interneuron of Homo sapiens. The standard transcriptomic reference data for this cell type can be found on the CellxGene census under the collection: 'Transcriptomic cytoarchitecture reveals principles of human neocortex organization', dataset: 'Supercluster: CGE-derived interneurons', Author Categories: 'CrossArea_subclass', Lamp5 Lhx6 http://purl.obolibrary.org/obo/UBERON_0001781 layer of retina http://purl.obolibrary.org/obo/UBERON_0022303 nervous system cell part layer Any of the layers that make up the retina[MP]. http://purl.obolibrary.org/obo/CL_4072027 sst GABAergic interneuron (Homo sapiens) http://purl.obolibrary.org/obo/CL_4023017 sst GABAergic interneuron A transcriptomically distinct GABAergic neuron located in the cerebral cortex that expresses somatostatin (sst). The standard transcriptomic reference data for this cell type can be found on the CellxGene census under the collection: 'Transcriptomic cytoarchitecture reveals principles of human neocortex organization', dataset: 'Supercluster: MGE-derived interneurons', Author Categories: 'CrossArea_subclass', cluster Sst. http://purl.obolibrary.org/obo/UBERON_0001782 pigmented layer of retina http://purl.obolibrary.org/obo/UBERON_0015808 eye epithelium A monolayer of pigmented epithelium covering the neural retina; develops from the outer of the two layers of the optic cup[ZFA]. the pigmented cell layer just outside the neurosensory retina that nourishes retinal visual cells, and is firmly attached to the underlying choroid and overlying retinal visual cells[WP]. http://purl.obolibrary.org/obo/CL_4072029 pvalb GABAergic interneuron (Homo sapiens) http://purl.obolibrary.org/obo/CL_4023018 pvalb GABAergic interneuron A transcriptomically distinct GABAergic interneuron with a soma located in a cerebral cortex and it expresses Parvalbumin. The standard transcriptomic reference data for this cell type can be found on the CellxGene census under the collection: 'Transcriptomic cytoarchitecture reveals principles of human neocortex organization', dataset: 'Supercluster: MGE-derived interneurons', Author Categories: 'CrossArea_subclass', cluster Pvalb. http://purl.obolibrary.org/obo/UBERON_0001786 fovea centralis http://purl.obolibrary.org/obo/UBERON_0000064 organ part A depression in the inner retinal surface within the macula lutea, the photoreceptor layer of which is entirely cones and which is specialized for maximum visual acuity. http://purl.obolibrary.org/obo/UBERON_0001787 photoreceptor layer of retina http://purl.obolibrary.org/obo/UBERON_0001781 layer of retina The layer within the retina where the photoreceptor cell receptor segments reside. http://purl.obolibrary.org/obo/CL_4072031 sst chodl GABAergic interneuron (Homo sapiens) http://purl.obolibrary.org/obo/CL_4023121 sst chodl GABAergic interneuron A transcriptomically distinct sst GABAergic interneuron that also expresses Chodl. These neurons are rare and correspond to the only known interneurons with long-range projection. The standard transcriptomic reference data for this cell type can be found on the CellxGene census under the collection: 'Transcriptomic cytoarchitecture reveals principles of human neocortex organization', dataset: 'Supercluster: MGE-derived interneurons', Author Categories: 'CrossArea_subclass', clusters Sst Chodl. http://purl.obolibrary.org/obo/UBERON_0001788 outer limiting layer of retina http://purl.obolibrary.org/obo/UBERON_0007619 limiting membrane of retina The row of jucntional complexes between the plasma membranes of rod segments and the Muller glia cells; this barrier separates the layer of inner and outer segments of the rods and cones from the outer nuclear layer and forms a blood-retina barrier[MP]. http://purl.obolibrary.org/obo/CL_4072032 VIP GABAergic interneuron (Homo sapiens) http://purl.obolibrary.org/obo/CL_4023016 VIP GABAergic interneuron A transcriptomically distinct GABAergic neuron that expresses the vasoactive intestinal polypeptide and that has its soma located in the forebrain. The standard transcriptomic reference data for this cell type can be found on the CellxGene census under the collection: 'Transcriptomic cytoarchitecture reveals principles of human neocortex organization', dataset: 'Supercluster: CGE-derived interneurons', Author Categories: 'CrossArea_subclass', cluster Vip. http://purl.obolibrary.org/obo/UBERON_0001789 outer nuclear layer of retina http://purl.obolibrary.org/obo/UBERON_0001781 layer of retina The layer within the retina where the photoreceptor cell bodies reside. http://purl.obolibrary.org/obo/CL_4072034 lamp5 GABAergic interneuron (Homo sapiens) http://purl.obolibrary.org/obo/CL_4023011 lamp5 GABAergic interneuron A transcriptomically distinct GABAergic neuron located in the cerebral cortex that expresses Lamp5. The standard transcriptomic reference data for this cell type can be found on the CellxGene census under the collection: 'Transcriptomic cytoarchitecture reveals principles of human neocortex organization', dataset: 'Supercluster: CGE-derived interneurons', Author Categories: 'CrossArea_subclass', clusters Lamp5. http://purl.obolibrary.org/obo/UBERON_0001790 outer plexiform layer of retina http://purl.obolibrary.org/obo/UBERON_0001781 layer of retina The layer within the retina where the bipolar cells synapse with the photoreceptor cells[ZFA]. Between the inner and outer nuclear layers, the outer plexiform layer (OPL) contains connections between the photoreceptors and bipolar and horizontal cells[GO]. http://purl.obolibrary.org/obo/CL_4072035 sncg GABAergic interneuron (Homo sapiens) http://purl.obolibrary.org/obo/CL_4023015 sncg GABAergic interneuron A transcriptomically distinct GABAergic neuron located in the cerebral cortex that expresses Gamma-synuclein. The standard transcriptomic reference data for this cell type can be found on the CellxGene census under the collection: 'Transcriptomic cytoarchitecture reveals principles of human neocortex organization', dataset: 'Supercluster: CGE-derived interneurons', Author Categories: 'CrossArea_subclass', clusters Sncg. http://purl.obolibrary.org/obo/UBERON_0001791 inner nuclear layer of retina http://purl.obolibrary.org/obo/UBERON_0001781 layer of retina Cytoarchitectural layer of retina containing closely packed cell bodies, the majority of which are bipolar cells (adapted from Wikipedia). http://purl.obolibrary.org/obo/CL_4072036 PAX6 GABAergic interneuron (Homo sapiens) http://purl.obolibrary.org/obo/CL_4042032 PAX6 GABAergic interneuron A transcriptomically distinct GABAergic neuron located in the cerebral cortex that expresses the transcript PAX6. The standard transcriptomic reference data for this cell type can be found on the CellxGene census under the collection: 'Transcriptomic cytoarchitecture reveals principles of human neocortex organization', dataset: 'Supercluster: CGE-derived interneurons', Author Categories: 'CrossArea_subclass', clusters PAX http://purl.obolibrary.org/obo/UBERON_0001792 ganglionic layer of retina http://purl.obolibrary.org/obo/UBERON_0001781 layer of retina Cytoarchitectural layer of retina that contains somata of retinal ganglion cells, bounded by the stratum opticum and the inner plexiform layer. http://purl.obolibrary.org/obo/CL_4072037 L2/3 intratelencephalic projecting glutamatergic neuron (Homo sapiens) http://purl.obolibrary.org/obo/CL_4030059 L2/3 intratelencephalic projecting glutamatergic neuron A transcriptomically distinct intratelencephalic-projecting glutamatergic neuron with a soma found between cortical layer 2-4. This intratelencephalic-projecting glutamatergic neuron has thin-tufted apical dendrites and extends its axonal projection into L5 in the neocortex. This neuronal type has a hyperpolarised resting membrane potential. The standard transcriptomic reference data for this cell type can be found on the CellxGene census under the collection: 'Transcriptomic cytoarchitecture reveals principles of human neocortex organization', dataset: 'Supercluster: IT-projecting excitatory neurons', Author Categories: 'CrossArea_subclass', clusters L2/3 IT. http://purl.obolibrary.org/obo/UBERON_0001793 nerve fiber layer of retina http://purl.obolibrary.org/obo/UBERON_0001781 layer of retina Layer of the retina formed by expansion of the fibers of the optic nerve. http://purl.obolibrary.org/obo/CL_4072038 L5 intratelencephalic projecting glutamatergic neuron (Homo sapiens) http://purl.obolibrary.org/obo/CL_4030064 L5 intratelencephalic projecting glutamatergic neuron An intratelencephalic-projecting glutamatergic neuron with a soma found in cortical layer 5. The standard transcriptomic reference data for this cell type can be found on the CellxGene census under the collection: 'Transcriptomic cytoarchitecture reveals principles of human neocortex organization', dataset: 'Supercluster: IT-projecting excitatory neurons', Author Categories: 'CrossArea_subclass', L5 IT. http://purl.obolibrary.org/obo/UBERON_0001794 inner limiting layer of retina http://purl.obolibrary.org/obo/UBERON_0007619 limiting membrane of retina The row of fused Muller cell processes and astrocytes that separates the retinal nerve fiber layer from the vitreous[MP]. http://purl.obolibrary.org/obo/CL_4072039 L4 intratelencephalic projecting glutamatergic neuron (Homo sapiens) http://purl.obolibrary.org/obo/CL_4030063 L4 intratelencephalic projecting glutamatergic neuron A transcriptomically distinct intratelencephalic-projecting glutamatergic neuron with a soma found in cortical layer 3-4. This neuron type can have a pyramidal, star-pyramidal or spiny stellate morphology and projects its output to L2/3 and L5A/B. The standard transcriptomic reference data for this cell type can be found on the CellxGene census under the collection: 'Transcriptomic cytoarchitecture reveals principles of human neocortex organization', dataset: 'Supercluster: IT-projecting excitatory neurons', Author Categories: 'CrossArea_subclass', L4 IT. http://purl.obolibrary.org/obo/UBERON_0001795 inner plexiform layer of retina http://purl.obolibrary.org/obo/UBERON_0001781 layer of retina Cytoarchitectural layer of the retina that is made up of a dense reticulum of fibrils formed by interlaced dendrites of retinal ganglion cells and cells of the inner nuclear layer (adapted from Wikipedia). http://purl.obolibrary.org/obo/CL_4072040 L6 intratelencephalic projecting Car3 glutamatergic neuron (Homo sapiens) http://purl.obolibrary.org/obo/CL_4030068 L6 intratelencephalic projecting Car3 glutamatergic neuron A transcriptomically distinct intratelencepalic-projecting glutamatergic neuron that expresses Car3 with a soma found in L6. The standard transcriptomic reference data for this cell type can be found on the CellxGene census under the collection: 'Transcriptomic cytoarchitecture reveals principles of human neocortex organization', dataset: 'Supercluster: IT-projecting excitatory neurons', Author Categories: 'CrossArea_cluster', L6 IT Car3. http://purl.obolibrary.org/obo/UBERON_0001796 aqueous humor of eyeball http://purl.obolibrary.org/obo/UBERON_0006314 bodily fluid A thick watery refractive medium that fills the space between the lens and the cornea[WP]. http://purl.obolibrary.org/obo/CL_4072041 L6 intratelencephalic projecting glutamatergic neuron (Homo sapiens) http://purl.obolibrary.org/obo/CL_4030065 L6 intratelencephalic projecting glutamatergic neuron A transcriptomically distinct intratelencephalic-projecting glutamatergic neuron with a soma found in L6 of the primary motor cortex. These cells are short untufted pyramidal cells, which could be stellate or inverted. The standard transcriptomic reference data for this cell type can be found on the CellxGene census under the collection: 'Transcriptomic cytoarchitecture reveals principles of human neocortex organization', dataset: 'Supercluster: IT-projecting excitatory neurons', Author Categories: 'CrossArea_subclass', L6 IT. http://purl.obolibrary.org/obo/UBERON_0001798 vitreous body http://purl.obolibrary.org/obo/UBERON_0011825 loose connective tissue Gelatinous mucoid tissue that is composed of vitreous humor and fills the cavity behind the crystalline lens of the eye and in front of the retina[MP,modified]. http://purl.obolibrary.org/obo/CL_4072042 L5/6 near-projecting glutamatergic neuron (Homo sapiens) http://purl.obolibrary.org/obo/CL_4030067 L5/6 near-projecting glutamatergic neuron A transcriptomically defined near-projecting glutamatergic neuron with a soma found in cortical layer 5/6 in humans. http://purl.obolibrary.org/obo/UBERON_0001799 vitreous chamber of eyeball http://purl.obolibrary.org/obo/UBERON_0006311 chamber of eyeball The chamber in the eyeball enclosing the vitreous humor, bounded anteriorly by the lens and ciliary body and posteriorly by the posterior wall of the eyeball[BTO,modified]. http://purl.obolibrary.org/obo/CL_4072043 L5 extratelencephalic projecting glutamatergic cortical neuron (Homo sapiens) http://purl.obolibrary.org/obo/CL_4023041 L5 extratelencephalic projecting glutamatergic cortical neuron A transcriptomically distinct glutamatergic neuron, with a soma found in the deeper portion of L5, that has long-range axonal projections including deep subcortical targets outside of the telencephalon and, in some cases, the spinal cord. While the L5 ET neuron projections are not limited to ET targets, they are clearly differentiated from the neuron subclasses whose projections are constrained to intratelencephalic (IT) targets. L5 ET neurons are generally the largest excitatory cortical neurons, typically having a thick apical dendrite with a prominent dendritic tuft in layer 1 and displaying burst-firing physiological characteristics. The standard transcriptomic reference data for this cell type can be found on the CellxGene census under the collection: 'Transcriptomic cytoarchitecture reveals principles of human neocortex organization', dataset: 'Supercluster: Deep layer (non-IT) excitatory neurons ', Author Categories: 'CrossArea_subclass', clusters L5 ET. http://purl.obolibrary.org/obo/UBERON_0001800 sensory ganglion http://purl.obolibrary.org/obo/UBERON_0000045 ganglion The clusters of neurons in the somatic peripheral nervous system which contain the cell bodies of sensory nerve axons, interneurons and non-neuronal supporting cells. http://purl.obolibrary.org/obo/CL_4072044 L6 corticothalamic-projecting glutamatergic cortical neuron (Homo sapiens) http://purl.obolibrary.org/obo/CL_4023042 L6 corticothalamic-projecting glutamatergic cortical neuron A transcriptomically distinct corticothalamic-projecting neuron with a soma found in cortical layer 6. The standard transcriptomic reference data for this cell type can be found on the CellxGene census under the collection: 'Transcriptomic cytoarchitecture reveals principles of human neocortex organization', dataset: 'Supercluster: Deep layer (non-IT) excitatory neurons', Author Categories: 'CrossArea_subclass', clusters L6 CT. http://purl.obolibrary.org/obo/UBERON_0001801 anterior segment of eyeball http://purl.obolibrary.org/obo/UBERON_0000063 organ subunit Any of the parts of the eye that lie in front of, or ventral to, the lens (inclusive). http://purl.obolibrary.org/obo/CL_4072045 L6b glutamatergic cortical neuron (Homo sapiens) http://purl.obolibrary.org/obo/CL_4023038 L6b glutamatergic cortical neuron A glutamatergic neuron with a soma found in cortical layer 6b. They are transcriptomically related to corticothalamic-projecting neurons but have differential projections to the thalamus or anterior cingulate. The standard transcriptomic reference data for this cell type can be found on the CellxGene census under the collection: 'Transcriptomic cytoarchitecture reveals principles of human neocortex organization', dataset: 'Supercluster: Deep layer (non-IT) excitatory neuron', Author Categories: 'CrossArea_subclass', cluster L6b. http://purl.obolibrary.org/obo/UBERON_0001802 posterior segment of eyeball http://purl.obolibrary.org/obo/UBERON_0000063 organ subunit Any of the parts of the eye that lie in back of, or dorsal to, the lens (but not inclusive). http://purl.obolibrary.org/obo/CL_4072046 pvalb chandelier GABAergic interneuron (Homo sapiens) http://purl.obolibrary.org/obo/CL_4023036 pvalb chandelier GABAergic interneuron A transcriptomically definined GABAergic interneuron of the human pallium. These cells correspond to the classically defined pvalb chandelier neuron type. The standard transcriptomic reference data for this cell type can be found on the CellxGene census under the collection: 'Transcriptomic cytoarchitecture reveals principles of human neocortex organization', dataset: 'Supercluster: CGE-derived interneurons', Author Categories: 'CrossArea_subclass', clusters Chandelier. http://purl.obolibrary.org/obo/UBERON_0001803 epithelium of lens http://purl.obolibrary.org/obo/UBERON_0015808 eye epithelium A layer of epithelial cells that is part of the eye. http://purl.obolibrary.org/obo/CL_7770002 juxtacanalicular tissue cell http://purl.obolibrary.org/obo/CL_0002367 trabecular meshwork cell A trabecular meshwork cell of the juxtacanalicular tissue (JCT), characterized by a spindle-shaped, fibroblast-like morphology within a loose extracellular matrix immediately adjacent to Schlemm's canal. It expresses CHI3L1 (human and mouse) and ANGPTL7 (human), as well as smooth muscle actin for contractility. Unlike other trabecular meshwork cells, it does not form monolayers but exists in a loose network, regulating aqueous humor outflow resistance through continuous ECM remodelling, mechanotransduction, and formation of intracellular pores historically called giant vacuoles. http://purl.obolibrary.org/obo/UBERON_0001804 capsule of lens http://purl.obolibrary.org/obo/UBERON_0005764 acellular membrane The elastic, clear, membrane-like structure, that is outer most layer of the lens. http://purl.obolibrary.org/obo/CL_7770003 beam A cell http://purl.obolibrary.org/obo/CL_7770005 beam cell A beam cell within the eye's trabecular meshwork, molecularly distinguished by FABP4 expression in humans and spatially intermingled with Beam B cells throughout the uveal and corneoscleral meshwork regions. In mice, a transcriptionally analogous Beam A–like cluster (mC14) exists, sharing core TM markers (Myoc, Mgp, Pdpn, Chil1) and functional attributes. http://purl.obolibrary.org/obo/UBERON_0001805 autonomic ganglion http://purl.obolibrary.org/obo/UBERON_0003338 ganglion of peripheral nervous system Ganglion that has dendrites that form a junction between autonomic nerves originating from the central nervous system and autonomic nerves innervating their target organs in the periphery. There are two subtypes, sympathetic ganglion and parasympathetic ganglion. http://purl.obolibrary.org/obo/CL_7770005 beam cell http://purl.obolibrary.org/obo/CL_0002367 trabecular meshwork cell A trabecular meshwork cell that is part of the eye's trabecular meshwork, residing in the uveal and corneoscleral meshwork regions and serving as the primary biological filter in the aqueous humor drainage cascade. This cell exhibits endothelial-like properties, including production of antithrombogenic substances such as tissue plasminogen activator, while also demonstrating phagocytic activity to remove cellular debris from aqueous humour before the fluid moves deeper into the less porous juxtacanalicular tissue. http://purl.obolibrary.org/obo/UBERON_0001806 sympathetic ganglion http://purl.obolibrary.org/obo/UBERON_0001805 autonomic ganglion A ganglion of the sympathetic nervous system. Examples: paravertebral and the prevertebral ganglia, which include the sympathetic chain ganglia, the superior, middle, and inferior cervical ganglia, and the aorticorenal, celiac, and stellate ganglia. http://purl.obolibrary.org/obo/CL_7770006 beam B cell, human http://purl.obolibrary.org/obo/CL_0002367 trabecular meshwork cell A trabecular meshwork cell within the eye's trabecular meshwork. This cell is molecularly distinguished by TMEFF2 expression in humans. A beam B cell is spatially intermingled with beam A cells throughout the uveal and corneoscleral meshwork regions, but demonstrates a tendency to localise closer to the juxtacanalicular tissue. http://purl.obolibrary.org/obo/UBERON_0001807 paravertebral ganglion http://purl.obolibrary.org/obo/UBERON_0007134 trunk ganglion Trunk ganglion which is part of a bilaterally paired set of sympathetic ganglia located anterior and lateral to the spinal cord. http://purl.obolibrary.org/obo/GO_0008219 cell death http://purl.obolibrary.org/obo/GO_0009987 cellular process Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as apoptotic bodies). The cell corpse (or its fragments) may be engulfed by an adjacent cell in vivo, but engulfment of whole cells should not be considered a strict criteria to define cell death as, under some circumstances, live engulfed cells can be released from phagosomes (see PMID:18045538). http://purl.obolibrary.org/obo/UBERON_0001808 parasympathetic ganglion http://purl.obolibrary.org/obo/UBERON_0010313 neural crest-derived structure Ganglion containing neurons that receive innervation from parasympathetic neurons in the central nervous system and subserves parasympathetic functions through innervation of smooth muscle, cardiac muscle and glands. http://purl.obolibrary.org/obo/GO_0008277 regulation of G protein-coupled receptor signaling pathway http://purl.obolibrary.org/obo/GO_0009966 regulation of signal transduction Any process that modulates the frequency, rate or extent of G protein-coupled receptor signaling pathway. http://purl.obolibrary.org/obo/UBERON_0001810 nerve plexus http://purl.obolibrary.org/obo/UBERON_0007651 anatomical junction Anatomical junction where subdivisions of two or more neural trees interconnect with one another to form a network through which nerve fibers of the constituent nerve trees become regrouped; together with other nerve plexuses, nerves and ganglia, it constitutes the peripheral nervous system. Examples: cervical nerve plexus, brachial nerve plexus, sacral nerve plexus[FMA]. http://purl.obolibrary.org/obo/GO_0008285 negative regulation of cell population proliferation http://purl.obolibrary.org/obo/GO_0042127 regulation of cell population proliferation Any process that stops, prevents or reduces the rate or extent of cell proliferation. http://purl.obolibrary.org/obo/UBERON_0001813 spinal nerve plexus http://purl.obolibrary.org/obo/UBERON_0001810 nerve plexus An intermingling of fiber fascicles from adjacent spinal nerves to form a network. http://purl.obolibrary.org/obo/GO_0008292 acetylcholine biosynthetic process http://purl.obolibrary.org/obo/GO_0009058 biosynthetic process The chemical reactions and pathways resulting in the formation of acetylcholine, the acetic acid ester of the organic base choline. http://purl.obolibrary.org/obo/UBERON_0001815 lumbosacral nerve plexus http://purl.obolibrary.org/obo/UBERON_0001813 spinal nerve plexus An arrangement of nerve fibers, running from the spine that travels to the pelvic appendage where it innervates skin and muscle. http://purl.obolibrary.org/obo/GO_0008299 isoprenoid biosynthetic process http://purl.obolibrary.org/obo/GO_0008610 lipid biosynthetic process The chemical reactions and pathways resulting in the formation of an isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues. http://purl.obolibrary.org/obo/GO_0008300 isoprenoid catabolic process http://purl.obolibrary.org/obo/GO_0016042 lipid catabolic process The chemical reactions and pathways resulting in the breakdown of an isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues. http://purl.obolibrary.org/obo/GO_0008320 protein transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0140318 protein transporter activity Enables the transfer of a protein from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0008328 ionotropic glutamate receptor complex http://purl.obolibrary.org/obo/GO_0098878 neurotransmitter receptor complex A multimeric assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand-gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex. http://purl.obolibrary.org/obo/GO_0008347 glial cell migration http://purl.obolibrary.org/obo/GO_0016477 cell migration The orderly movement of a glial cell, non-neuronal cells that provide support and nutrition, maintain homeostasis, form myelin, and participate in signal transmission in the nervous system. http://purl.obolibrary.org/obo/GO_0008355 olfactory learning http://purl.obolibrary.org/obo/GO_0042048 olfactory behavior Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs in response to (repeated) exposure to an olfactory cue. http://purl.obolibrary.org/obo/GO_0008366 axon ensheathment http://purl.obolibrary.org/obo/GO_0007272 ensheathment of neurons Any process in which the axon of a neuron is insulated, and that insulation maintained, thereby preventing dispersion of the electrical signal. http://purl.obolibrary.org/obo/GO_0008502 melatonin receptor activity http://purl.obolibrary.org/obo/GO_0004930 G protein-coupled receptor activity Combining with melatonin, N-acetyl-5-methoxytryptamine, to initiate a change in cell activity. Melatonin is a neuroendocrine substance that stimulates the aggregation of melanosomes in melanophores, thus lightening the skin. http://purl.obolibrary.org/obo/GO_0008544 epidermis development http://purl.obolibrary.org/obo/GO_0009888 tissue development The process whose specific outcome is the progression of the epidermis over time, from its formation to the mature structure. The epidermis is the outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species. http://purl.obolibrary.org/obo/GO_0008584 male gonad development http://purl.obolibrary.org/obo/GO_0008406 gonad development The process whose specific outcome is the progression of the male gonad over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/UBERON_0001816 autonomic nerve plexus http://purl.obolibrary.org/obo/UBERON_0001810 nerve plexus A nerve plexus that is part of an autonomic nervous system [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0008594 photoreceptor cell morphogenesis http://purl.obolibrary.org/obo/GO_0048667 cell morphogenesis involved in neuron differentiation The process in which the structures of a photoreceptor cell are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a photoreceptor cell, a sensory cell that reacts to the presence of light. An example of this is found in Drosophila melanogaster. http://purl.obolibrary.org/obo/GO_0008645 hexose transmembrane transport http://purl.obolibrary.org/obo/GO_0015749 monosaccharide transmembrane transport The process in which hexose is transported across a membrane. Hexoses are aldoses with a chain of six carbon atoms in the molecule. http://purl.obolibrary.org/obo/UBERON_0001823 nasal cartilage http://purl.obolibrary.org/obo/UBERON_0007844 cartilage element One of the cartilage structures in the nose that provide form and support[WP]. http://purl.obolibrary.org/obo/GO_0009056 catabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process A cellular process consisting of the biochemical pathways by which a living organism breaks down substances. This includes the breakdown of carbon compounds with the liberation of energy for use by the cell or organism. http://purl.obolibrary.org/obo/UBERON_0001824 mucosa of larynx http://purl.obolibrary.org/obo/UBERON_0004785 respiratory system mucosa The mucous lining of the larynx, which is composed of squamous epithelium in the upper larynx and ciliated columnar epithelium in the lower larynx. http://purl.obolibrary.org/obo/GO_0009133 nucleoside diphosphate biosynthetic process http://purl.obolibrary.org/obo/GO_1901293 nucleoside phosphate biosynthetic process The chemical reactions and pathways resulting in the formation of a nucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with diphosphate on the sugar. http://purl.obolibrary.org/obo/UBERON_0001826 nasal cavity mucosa http://purl.obolibrary.org/obo/UBERON_0004785 respiratory system mucosa The mucous membrane that lines the nasal cavity[MP]. http://purl.obolibrary.org/obo/GO_0009134 nucleoside diphosphate catabolic process http://purl.obolibrary.org/obo/GO_1901292 nucleoside phosphate catabolic process The chemical reactions and pathways resulting in the breakdown of a nucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with diphosphate on the sugar. http://purl.obolibrary.org/obo/UBERON_0001827 secretion of lacrimal gland http://purl.obolibrary.org/obo/UBERON_0000456 secretion of exocrine gland Aqueous substance secreted by the lacrimal gland. http://purl.obolibrary.org/obo/GO_0009135 purine nucleoside diphosphate metabolic process http://purl.obolibrary.org/obo/GO_0009132 nucleoside diphosphate metabolic process The chemical reactions and pathways involving purine nucleoside diphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar. http://purl.obolibrary.org/obo/UBERON_0001829 major salivary gland http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure One of the three largest glands of the oral cavity that secrete most of the saliva, including the parotid, submandibular, and sublingual glands. http://purl.obolibrary.org/obo/GO_0009136 purine nucleoside diphosphate biosynthetic process http://purl.obolibrary.org/obo/GO_0009135 purine nucleoside diphosphate metabolic process The chemical reactions and pathways resulting in the formation of purine nucleoside diphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar. http://purl.obolibrary.org/obo/UBERON_0001836 saliva http://purl.obolibrary.org/obo/UBERON_0000456 secretion of exocrine gland A fluid produced in the oral cavity by salivary glands, typically used in predigestion, but also in other functions. http://purl.obolibrary.org/obo/GO_0009137 purine nucleoside diphosphate catabolic process http://purl.obolibrary.org/obo/GO_0009135 purine nucleoside diphosphate metabolic process The chemical reactions and pathways resulting in the breakdown of purine nucleoside diphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar. http://purl.obolibrary.org/obo/UBERON_0001837 duct of salivary gland http://purl.obolibrary.org/obo/UBERON_0003928 digestive system duct The duct of a salivary gland. http://purl.obolibrary.org/obo/GO_0009141 nucleoside triphosphate metabolic process http://purl.obolibrary.org/obo/GO_0006753 nucleoside phosphate metabolic process The chemical reactions and pathways involving a nucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with triphosphate on the sugar. http://purl.obolibrary.org/obo/UBERON_0001838 sublingual duct http://purl.obolibrary.org/obo/UBERON_0001837 duct of salivary gland A duct of a sublingual gland. http://purl.obolibrary.org/obo/GO_0009142 nucleoside triphosphate biosynthetic process http://purl.obolibrary.org/obo/GO_1901293 nucleoside phosphate biosynthetic process The chemical reactions and pathways resulting in the formation of a nucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with triphosphate on the sugar. http://purl.obolibrary.org/obo/UBERON_0001839 bony labyrinth http://purl.obolibrary.org/obo/UBERON_0034921 multi organ part structure A system of fluid passages in the inner ear, including both the cochlea, which is part of the auditory system, and the vestibular system, which provides the sense of balance. The bony labyrinth, or osseous labyrinth, is the network of passages with bony walls lined with periosteum. The bony labyrinth is lined with the membranous labyrinth. There is a layer of perilymph between them. The three parts of the bony labyrinth are the vestibule of the ear, the semicircular canals, and the cochlea. The vestibular system is the region of the inner ear where the semicircular canals converge, close to the cochlea (the hearing organ). The vestibular system works with the visual system to keep objects in focus when the head is moving. Joint and muscle receptors also are important in maintaining balance. The brain receives, interprets, and processes the information from these systems that control our balance. [WP,unvetted]. http://purl.obolibrary.org/obo/GO_0009143 nucleoside triphosphate catabolic process http://purl.obolibrary.org/obo/GO_1901292 nucleoside phosphate catabolic process The chemical reactions and pathways resulting in the breakdown of a nucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with triphosphate on the sugar. http://purl.obolibrary.org/obo/UBERON_0001840 semicircular canal http://purl.obolibrary.org/obo/UBERON_0000025 tube One of three half-circular, interconnected tubes located inside each ear[WP]. http://purl.obolibrary.org/obo/GO_0009144 purine nucleoside triphosphate metabolic process http://purl.obolibrary.org/obo/GO_0009141 nucleoside triphosphate metabolic process The chemical reactions and pathways involving purine nucleoside triphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar. http://purl.obolibrary.org/obo/UBERON_0001844 cochlea http://purl.obolibrary.org/obo/UBERON_0034921 multi organ part structure The spiral-shaped bony canal in the inner ear containing the hair cells that transduce sound. Its core component is the Organ of Corti, the sensory organ of hearing, which is distributed along the partition separating fluid chambers in the coiled tapered tube of the cochlea. [WP,modified]. http://purl.obolibrary.org/obo/GO_0009145 purine nucleoside triphosphate biosynthetic process http://purl.obolibrary.org/obo/GO_0009144 purine nucleoside triphosphate metabolic process The chemical reactions and pathways resulting in the formation of purine nucleoside triphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar. http://purl.obolibrary.org/obo/UBERON_0001845 perilymph http://purl.obolibrary.org/obo/UBERON_0006586 otolymph Transudate contained in the osseous labyrinth outside the membranous labyrinth.[FMA]. http://purl.obolibrary.org/obo/GO_0009146 purine nucleoside triphosphate catabolic process http://purl.obolibrary.org/obo/GO_0009144 purine nucleoside triphosphate metabolic process The chemical reactions and pathways resulting in the breakdown of purine nucleoside triphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar. http://purl.obolibrary.org/obo/UBERON_0001848 auricular cartilage http://purl.obolibrary.org/obo/UBERON_0034944 zone of organ Cartilage of the pinna and much of the external ear canal. http://purl.obolibrary.org/obo/GO_0009150 purine ribonucleotide metabolic process http://purl.obolibrary.org/obo/GO_0009259 ribonucleotide metabolic process The chemical reactions and pathways involving a purine ribonucleotide, a compound consisting of ribonucleoside (a purine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. http://purl.obolibrary.org/obo/UBERON_0001849 membranous labyrinth http://purl.obolibrary.org/obo/UBERON_0000062 organ Organ with organ cavity which consists of the vestibular labyrinth and the cochlear labyrinth. The membranous labyrinth is lodged within the bony labyrinth and has the same general form; it is, however, considerably smaller and is partly separated from the bony walls by a quantity of fluid, the perilymph.[FMA, WP]. http://purl.obolibrary.org/obo/GO_0009179 purine ribonucleoside diphosphate metabolic process http://purl.obolibrary.org/obo/GO_0009185 ribonucleoside diphosphate metabolic process The chemical reactions and pathways involving purine ribonucleoside diphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with diphosphate on the sugar. http://purl.obolibrary.org/obo/UBERON_0001850 lacrimal drainage system http://purl.obolibrary.org/obo/UBERON_0004111 anatomical conduit A collection of channels that connects the conjunctival sac with the nasal cavity, encompassing the lacrimal ducts, the lacrimal sac and the naso-lacrimal duct. http://purl.obolibrary.org/obo/UBERON_0001851 cortex http://purl.obolibrary.org/obo/UBERON_0000064 organ part Outermost layer of an organ[WP]. http://purl.obolibrary.org/obo/GO_0009181 purine ribonucleoside diphosphate catabolic process http://purl.obolibrary.org/obo/GO_0009191 ribonucleoside diphosphate catabolic process The chemical reactions and pathways resulting in the breakdown of purine ribonucleoside diphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with diphosphate on the sugar. http://purl.obolibrary.org/obo/UBERON_0001853 utricle of membranous labyrinth http://purl.obolibrary.org/obo/UBERON_0002518 otolith organ The larger of the two otolith organs in the vestibule. http://purl.obolibrary.org/obo/GO_0009185 ribonucleoside diphosphate metabolic process http://purl.obolibrary.org/obo/GO_0009132 nucleoside diphosphate metabolic process The chemical reactions and pathways involving a ribonucleoside diphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with diphosphate on the sugar. http://purl.obolibrary.org/obo/UBERON_0001854 saccule of membranous labyrinth http://purl.obolibrary.org/obo/UBERON_0002518 otolith organ The smaller of the two otolith organs in the vestibule. http://purl.obolibrary.org/obo/GO_0009188 ribonucleoside diphosphate biosynthetic process http://purl.obolibrary.org/obo/GO_0009185 ribonucleoside diphosphate metabolic process The chemical reactions and pathways resulting in the formation of a ribonucleoside diphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with diphosphate on the sugar. http://purl.obolibrary.org/obo/UBERON_0001855 cochlear duct of membranous labyrinth http://purl.obolibrary.org/obo/UBERON_0000025 tube An endolymph filled cavity inside the cochlea, located in between the scala tympani and the scala vestibuli, separated by the basilar membrane and Reissner's membrane (the vestibular membrane) respectively. Houses the organ of Corti[WP]. http://purl.obolibrary.org/obo/GO_0009191 ribonucleoside diphosphate catabolic process http://purl.obolibrary.org/obo/GO_0009185 ribonucleoside diphosphate metabolic process The chemical reactions and pathways resulting in the breakdown of a ribonucleoside diphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with diphosphate on the sugar. http://purl.obolibrary.org/obo/UBERON_0001856 semicircular duct http://purl.obolibrary.org/obo/UBERON_0000025 tube Any of the three loop-shaped membranous inner tubular parts of the semicircular canals that are about one-fourth the diameter of the corresponding outer bony canals, that communicate at each end with the utricle, and that have near one end an expanded ampulla containing an area of sensory epithelium. http://purl.obolibrary.org/obo/UBERON_0001862 vestibular labyrinth http://purl.obolibrary.org/obo/UBERON_0000064 organ part The part of the membranous labyrinth that includes the utricle and saccule lodged within the vestibule and the semicircular ducts lodged eccentrically in the corresponding canals. http://purl.obolibrary.org/obo/GO_0009201 ribonucleoside triphosphate biosynthetic process http://purl.obolibrary.org/obo/GO_0009142 nucleoside triphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of a ribonucleoside triphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with triphosphate on the sugar. http://purl.obolibrary.org/obo/UBERON_0001866 sebum http://purl.obolibrary.org/obo/UBERON_0000456 secretion of exocrine gland Fatty lubricant matter secreted by sebaceous glands, and made of made of triglyceride oils, wax, squalene, and metabolytes of fat-producing cells[BTO,WP]. http://purl.obolibrary.org/obo/GO_0009203 ribonucleoside triphosphate catabolic process http://purl.obolibrary.org/obo/GO_0009143 nucleoside triphosphate catabolic process The chemical reactions and pathways resulting in the breakdown of a ribonucleoside triphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with triphosphate on the sugar. http://purl.obolibrary.org/obo/UBERON_0001867 cartilage of external ear http://purl.obolibrary.org/obo/UBERON_0007844 cartilage element A cartilage that is part of a external ear [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0009205 purine ribonucleoside triphosphate metabolic process http://purl.obolibrary.org/obo/GO_0009144 purine nucleoside triphosphate metabolic process The chemical reactions and pathways involving purine ribonucleoside triphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with triphosphate on the sugar. http://purl.obolibrary.org/obo/UBERON_0001868 skin of chest http://purl.obolibrary.org/obo/UBERON_0001418 skin of thorax A zone of skin that is part of a chest [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0009259 ribonucleotide metabolic process http://purl.obolibrary.org/obo/GO_0019693 ribose phosphate metabolic process The chemical reactions and pathways involving a ribonucleotide, a compound consisting of ribonucleoside (a base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. http://purl.obolibrary.org/obo/UBERON_0001870 frontal cortex http://purl.obolibrary.org/obo/UBERON_0016529 cortex of cerebral lobe Anterior portion of the neocortex, lying anterior to the central sulcus in humans. It is bounded by the parietal cortex posteriorly and the temporal cortex laterally[NIFSTD,modified]. http://purl.obolibrary.org/obo/GO_0009260 ribonucleotide biosynthetic process http://purl.obolibrary.org/obo/GO_0009259 ribonucleotide metabolic process The chemical reactions and pathways resulting in the formation of a ribonucleotide, a compound consisting of ribonucleoside (a base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. http://purl.obolibrary.org/obo/UBERON_0001873 caudate nucleus http://purl.obolibrary.org/obo/UBERON_0009663 telencephalic nucleus Subcortical nucleus of telecephalic origin consisting of an elongated gray mass lying lateral to and bordering the lateral ventricle. It is divided into a head, body and tail in some species. http://purl.obolibrary.org/obo/GO_0009261 ribonucleotide catabolic process http://purl.obolibrary.org/obo/GO_0009259 ribonucleotide metabolic process The chemical reactions and pathways resulting in the breakdown of a ribonucleotide, a compound consisting of ribonucleoside (a base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. http://purl.obolibrary.org/obo/UBERON_0001874 putamen http://purl.obolibrary.org/obo/UBERON_0009663 telencephalic nucleus Subcortical nucleus of telencephalic , which together with the caudate nucleus, forms the striatum. The putamen lies lateral to the internal capsule and medial to the external medullary lamina, and is separated from the caudate nucleus by the fibers of the internal capsule for most of its length, except at its anterior portion. http://purl.obolibrary.org/obo/GO_0009266 response to temperature stimulus http://purl.obolibrary.org/obo/GO_0009628 response to abiotic stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temperature stimulus. http://purl.obolibrary.org/obo/UBERON_0001875 globus pallidus http://purl.obolibrary.org/obo/UBERON_0009663 telencephalic nucleus Subcortical nucleus, functionally part of the basal ganglia, which consists of two segments the external (or lateral) and internal (or medial) separated by the medial medullary lamina in primates. In rodents, The globus pallidus lateral is separated from the medial segment by the fibers of the internal capsule/cerebral peduncle. http://purl.obolibrary.org/obo/GO_0009295 nucleoid http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure The region of a virus, bacterial cell, mitochondrion or chloroplast to which the nucleic acid is confined. http://purl.obolibrary.org/obo/UBERON_0001876 amygdala http://purl.obolibrary.org/obo/UBERON_0005401 cerebral hemisphere gray matter Subcortical brain region lying anterior to the hippocampal formation in the temporal lobe and anterior to the temporal horn of the lateral ventricle in some species. It is usually subdivided into several groups. Functionally, it is not considered a unitary structure (MM). http://purl.obolibrary.org/obo/GO_0009308 amine metabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process The chemical reactions and pathways involving any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom. http://purl.obolibrary.org/obo/UBERON_0001877 medial septal nucleus http://purl.obolibrary.org/obo/UBERON_0009663 telencephalic nucleus Cells lying generally in front of Regional_part_of_septal_nuclei, lying ventral to and slightly medial to the lateral septal nucleus. Neurons in this nucleus give rise to the bulk of efferents from the septal nuclei. A major projection from the medial septal nucleus terminates in the hippocampal formation (Adapted from Brodal, 1981). http://purl.obolibrary.org/obo/GO_0009309 amine biosynthetic process http://purl.obolibrary.org/obo/GO_0009308 amine metabolic process The chemical reactions and pathways resulting in the formation of any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom. http://purl.obolibrary.org/obo/UBERON_0001879 nucleus of diagonal band http://purl.obolibrary.org/obo/UBERON_0009663 telencephalic nucleus A brain structure that is part of the septal nuclear complex. It is connected with the hippocampus, hypothalamus and amygdala. http://purl.obolibrary.org/obo/GO_0009310 amine catabolic process http://purl.obolibrary.org/obo/GO_0009308 amine metabolic process The chemical reactions and pathways resulting in the breakdown of any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom. http://purl.obolibrary.org/obo/UBERON_0001881 island of Calleja http://purl.obolibrary.org/obo/UBERON_0009663 telencephalic nucleus One of the seven small groups of granule cells in the polymorph layer of the olfactory tubercle and one large group, the insula magna, which lies along the border between septum, nucleus accumbens and nucleus of the diagonal band. http://purl.obolibrary.org/obo/GO_0009314 response to radiation http://purl.obolibrary.org/obo/GO_0009628 response to abiotic stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation. http://purl.obolibrary.org/obo/UBERON_0001882 nucleus accumbens http://purl.obolibrary.org/obo/UBERON_0009663 telencephalic nucleus A region of the brain consisting of a collection of neurons located in the forebrain ventral to the caudate and putamen. (caudoputamen in rodent) and continuous with these structures. There is no distinct boundary between the nucleus accumbens and the caudate/putamen, but in rodents, it can be identified by its lack of traversing fiber bundles in comparison to the dorsal striatum. Its principle neuron is the medium spiny neuron. Together with the neostriatum (caudate nucleus and putamen), the nucleus accumbens forms the striatum. http://purl.obolibrary.org/obo/GO_0009399 nitrogen fixation http://purl.obolibrary.org/obo/GO_0071941 nitrogen cycle metabolic process The process in which nitrogen is taken from its relatively inert molecular form (N2) in the atmosphere and converted into ammonium, which is more biologically available. http://purl.obolibrary.org/obo/UBERON_0001883 olfactory tubercle http://purl.obolibrary.org/obo/UBERON_0009663 telencephalic nucleus Region in the ventral telencephalon, prominent in rodents, but present in all mammals, consisting of a laminated cortical part and the cap/hilus region. It is traditionally viewed as part of the olfactory cortex but recognized by some as having a striatal character. According to many authors, the structure of the OT transitions from cortical like to striatal like along the lateral medial axis. (Maryann Martone). http://purl.obolibrary.org/obo/GO_0009411 response to UV http://purl.obolibrary.org/obo/GO_0009416 response to light stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultraviolet radiation (UV light) stimulus. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers. http://purl.obolibrary.org/obo/UBERON_0001884 phrenic nerve http://purl.obolibrary.org/obo/UBERON_0003443 thoracic cavity nerve A nerve that arises from the caudal cervical nerves and is primarily the motor nerve of the diaphragm but also sends sensory fibers to the pericardium. http://purl.obolibrary.org/obo/GO_0009414 response to water deprivation http://purl.obolibrary.org/obo/GO_0009415 response to water Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water deprivation stimulus, prolonged deprivation of water. http://purl.obolibrary.org/obo/UBERON_0001885 dentate gyrus of hippocampal formation http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain Part of the hippocampal formation forming a 'V' or 'U' shaped structure with the opening bounded by hippocampal area CA3. It consists of 3 layers from superficial to deep: molecular, granule cell and polymorphic or hilar layer. http://purl.obolibrary.org/obo/GO_0009415 response to water http://purl.obolibrary.org/obo/GO_1901700 response to oxygen-containing compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of water. http://purl.obolibrary.org/obo/UBERON_0001888 lateral olfactory stria http://purl.obolibrary.org/obo/UBERON_0034730 olfactory tract linking bulb to ipsilateral dorsal telencephalon White matter tract that contains projections from the olfactory bulb to the olfactory cortex (Maryann Martone). http://purl.obolibrary.org/obo/GO_0009448 gamma-aminobutyric acid metabolic process http://purl.obolibrary.org/obo/GO_0170041 non-proteinogenic amino acid metabolic process The chemical reactions and pathways involving gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms. http://purl.obolibrary.org/obo/UBERON_0001890 forebrain http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure The most anterior region of the brain including both the telencephalon and diencephalon. http://purl.obolibrary.org/obo/GO_0009449 gamma-aminobutyric acid biosynthetic process http://purl.obolibrary.org/obo/GO_0170043 non-proteinogenic amino acid biosynthetic process The chemical reactions and pathways resulting in the formation of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms. http://purl.obolibrary.org/obo/UBERON_0001891 midbrain http://purl.obolibrary.org/obo/UBERON_0010314 structure with developmental contribution from neural crest The midbrain is the middle division of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes a ventral part containing the cerebral peduncles and a dorsal tectum containing the corpora quadrigemina and that surrounds the aqueduct of Sylvius connecting the third and fourth ventricles)[GO]. http://purl.obolibrary.org/obo/GO_0009450 gamma-aminobutyric acid catabolic process http://purl.obolibrary.org/obo/GO_0170044 non-proteinogenic amino acid catabolic process The chemical reactions and pathways resulting in the breakdown of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms. http://purl.obolibrary.org/obo/UBERON_0001892 rhombomere http://purl.obolibrary.org/obo/UBERON_0004731 neuromere A segment of the developing hindbrain[ZFA]. In the vertebrate embryo, a rhombomere is a transiently divided segment of the developing neural tube, within the hindbrain region (a neuromere) in the area that will eventually become the rhombencephalon. The rhombomeres appear as a series of slightly constricted swellings in the neural tube, caudal to the cephalic flexure.[WP]. http://purl.obolibrary.org/obo/UBERON_0001895 metencephalon http://purl.obolibrary.org/obo/UBERON_0004733 segmental subdivision of hindbrain Rostral segment of the hindbrain that has as its parts the pons (where present) and the cerebellum[WP,modified]. http://purl.obolibrary.org/obo/GO_0009507 chloroplast http://purl.obolibrary.org/obo/GO_0009536 plastid A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma. http://purl.obolibrary.org/obo/UBERON_0001896 medulla oblongata http://purl.obolibrary.org/obo/UBERON_0000064 organ part Organ component of neuraxis that has as its parts the medullary reticular formation, inferior olivary complex and cochlear nuclear complex, among other structures[FMA]. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate[GO]. http://purl.obolibrary.org/obo/GO_0009508 plastid chromosome http://purl.obolibrary.org/obo/GO_0005694 chromosome A circular DNA molecule containing plastid encoded genes. http://purl.obolibrary.org/obo/UBERON_0001897 dorsal plus ventral thalamus http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure Subcortical brain region consisting of paired gray matter bodies in the dorsal diencephalon and forming part of the lateral wall of the third ventricle of the brain. The thalamus represents the major portion of the diencephalon and is commonly divided into cellular aggregates known as nuclear groups.(MeSH). The dorsal topographic division of the interbrain. The macrodissected adult human thalamus was clearly illustrated by Vesalius in 1543 and the term as defined here was introduced by His in 1893. It includes the traditional epithalamus, dorsal thalamus, and ventral thalamus of Herrick (1910, pp. 494, 498). Also see Kuhlenbeck (1927, Ch. 9) and Jones (1985, p. 87). http://purl.obolibrary.org/obo/GO_0009526 plastid envelope http://purl.obolibrary.org/obo/GO_0031967 organelle envelope The double lipid bilayer enclosing a plastid and separating its contents from the rest of the cytoplasm; includes the intermembrane space. http://purl.obolibrary.org/obo/UBERON_0001898 hypothalamus http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain A specialized brain region of the ventral diencephalon arising near the end of the segmentation period; the embryonic hypothalamic region will give rise to the posterior pituitary gland as well as a number of brain nuclei. [ZFA]. One of the most important functions of the hypothalamus is to link the nervous system to the endocrine system via the pituitary gland (hypophysis).[Wikipedia]. http://purl.obolibrary.org/obo/GO_0009527 plastid outer membrane http://purl.obolibrary.org/obo/GO_0042170 plastid membrane The outer, i.e. cytoplasm-facing, lipid bilayer of the plastid envelope. http://purl.obolibrary.org/obo/UBERON_0001899 epithalamus http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain Most dorsal part of the thalamus, comprising the pineal gland and habenular nuclei in most vertebrates. In a few vertebrates, it also includes the parietal eye. (Butler and Hodos, Comparative Vertebrate Neuroanatomy, 2nd ed, 2005, pg. 345-346. http://purl.obolibrary.org/obo/GO_0009532 plastid stroma http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure The proteinaceous ground substance of plastids. http://purl.obolibrary.org/obo/UBERON_0001900 ventral thalamus http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain Anterior part of the diencephalon that lies between the dorsal thalamus, hypothalamus, and tegmentum of the mesencephalon, including subthalamic nucleus, zona incerta, the fields of Forel, and the nucleus of ansa lenticularis[GO, modified]. http://purl.obolibrary.org/obo/GO_0009570 chloroplast stroma http://purl.obolibrary.org/obo/GO_0009532 plastid stroma The space enclosed by the double membrane of a chloroplast but excluding the thylakoid space. It contains DNA, ribosomes and some temporary products of photosynthesis. http://purl.obolibrary.org/obo/UBERON_0001901 epithelium of trachea http://purl.obolibrary.org/obo/UBERON_0008397 tracheobronchial epithelium The epithelial lining of the trachea which contains numerous ciliated cells. http://purl.obolibrary.org/obo/GO_0009581 detection of external stimulus http://purl.obolibrary.org/obo/GO_0051606 detection of stimulus The series of events in which an external stimulus is received by a cell and converted into a molecular signal. http://purl.obolibrary.org/obo/UBERON_0001902 epithelium of small intestine http://purl.obolibrary.org/obo/UBERON_0001277 intestinal epithelium An epithelium that is part of a small intestine [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0009582 detection of abiotic stimulus http://purl.obolibrary.org/obo/GO_0051606 detection of stimulus The series of events in which an (non-living) abiotic stimulus is received by a cell and converted into a molecular signal. http://purl.obolibrary.org/obo/UBERON_0001906 subthalamic nucleus http://purl.obolibrary.org/obo/UBERON_0015234 nucleus of ventral thalamus The subthalamic nucleus is the lens-shaped nucleus located in the ventral part of the subthalamus on the inner aspect of the internal capsule that is concerned with the integration of somatic motor function[GO]. http://purl.obolibrary.org/obo/GO_0009636 response to toxic substance http://purl.obolibrary.org/obo/GO_0042221 response to chemical Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus. http://purl.obolibrary.org/obo/UBERON_0001907 zona incerta http://purl.obolibrary.org/obo/UBERON_0015234 nucleus of ventral thalamus The zona incerta is a horizontally elongated region of gray matter cells in the subthalamus below the thalamus. Its connections project extensively over the brain from the cerebral cortex down into the spinal cord. Its function is unknown though several have been proposed related to 'limbic-motor integration' such as controlling visceral activity and pain; gating sensory input and synchronizing cortical and subcortical brain rhythms. Its dysfunction may play a role in central pain syndrome. It is also been identified as a promising deep brain stimulation therapy target for treating Parkinsons Disease. Its existence was first described by Auguste Forel in 1877 as a 'region of which nothing certain can be said'. A hundred and thirty years later in 2007, Nadia Urbain and Martin Deschênes of Université Laval noted that the 'zona incerta is among the least studied regions of the brain; its name does not even appear in the index of many textbooks. ' [WP,unvetted]. http://purl.obolibrary.org/obo/GO_0009657 plastid organization http://purl.obolibrary.org/obo/GO_0006996 organelle organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a plastid. http://purl.obolibrary.org/obo/UBERON_0001911 mammary gland http://purl.obolibrary.org/obo/UBERON_0019319 exocrine gland of integumental system A specialized accessory gland of the skin of mammals that secretes milk. The gland is typically only developed in females, and regresses in males. http://purl.obolibrary.org/obo/GO_0009658 chloroplast organization http://purl.obolibrary.org/obo/GO_0009657 plastid organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the chloroplast. http://purl.obolibrary.org/obo/UBERON_0001912 lobule of mammary gland http://purl.obolibrary.org/obo/UBERON_0009911 lobule Organ component of the mammary gland which consists of an aggregate of mammary alveoli that communicate with a lobular lactiferous duct.[FMA]. http://purl.obolibrary.org/obo/GO_0009665 plastid inheritance http://purl.obolibrary.org/obo/GO_0009657 plastid organization The partitioning of plastids between daughter cells at cell division. http://purl.obolibrary.org/obo/UBERON_0001913 milk http://purl.obolibrary.org/obo/UBERON_0006539 mammary gland fluid/secretion An emulsion of fat globules within a fluid that is secreted by the mammary gland during lactation. http://purl.obolibrary.org/obo/GO_0009666 plastid outer membrane organization http://purl.obolibrary.org/obo/GO_0009668 plastid membrane organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the outer membrane of a plastid. http://purl.obolibrary.org/obo/UBERON_0001915 endothelium of capillary http://purl.obolibrary.org/obo/UBERON_0008339 microvascular endothelium An endothelium that is part of a capillary [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0009668 plastid membrane organization http://purl.obolibrary.org/obo/GO_0061024 membrane organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of either of the lipid bilayers surrounding a plastid. http://purl.obolibrary.org/obo/UBERON_0001916 endothelium of arteriole http://purl.obolibrary.org/obo/UBERON_0008339 microvascular endothelium An endothelium that is part of an arteriole [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0009707 chloroplast outer membrane http://purl.obolibrary.org/obo/GO_0031969 chloroplast membrane The outer, i.e. cytoplasm-facing, lipid bilayer of the chloroplast envelope. http://purl.obolibrary.org/obo/UBERON_0001917 endothelium of artery http://purl.obolibrary.org/obo/UBERON_0004700 arterial system endothelium An endothelium that is part of an artery [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0009713 catechol-containing compound biosynthetic process http://purl.obolibrary.org/obo/GO_0046189 phenol-containing compound biosynthetic process The chemical reactions and pathways resulting in the formation of catechol-containing compounds. Catechol is a compound containing a pyrocatechol nucleus or substituent. http://purl.obolibrary.org/obo/UBERON_0001918 endothelium of venule http://purl.obolibrary.org/obo/UBERON_0008339 microvascular endothelium An endothelium that is part of a venule [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0009719 response to endogenous stimulus http://purl.obolibrary.org/obo/GO_0050896 response to stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus arising within the organism. http://purl.obolibrary.org/obo/UBERON_0001919 endothelium of vein http://purl.obolibrary.org/obo/UBERON_0004701 venous system endothelium An endothelium that is part of a vein [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0009725 response to hormone http://purl.obolibrary.org/obo/GO_0009719 response to endogenous stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus. http://purl.obolibrary.org/obo/UBERON_0001926 lateral geniculate body http://purl.obolibrary.org/obo/UBERON_0015233 nucleus of dorsal thalamus The group of neurons that serve as the primary processor of visual information received from the retina via the optic tract and send processed information to the visual cortex of the occipital lobe. http://purl.obolibrary.org/obo/GO_0009743 response to carbohydrate http://purl.obolibrary.org/obo/GO_1901700 response to oxygen-containing compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbohydrate stimulus. http://purl.obolibrary.org/obo/UBERON_0001928 preoptic area http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain Area of the forebrain between the anterior commissure and optic chiasm. http://purl.obolibrary.org/obo/GO_0009746 response to hexose http://purl.obolibrary.org/obo/GO_0034284 response to monosaccharide Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hexose stimulus. http://purl.obolibrary.org/obo/UBERON_0001930 paraventricular nucleus of hypothalamus http://purl.obolibrary.org/obo/UBERON_0006568 hypothalamic nucleus Nucleus in the anterior part of the hypothalamus. (MSH) * one of the magnocellular hypothalamic nuclei, an elongated plate of large, deeply staining cells located close to the third ventricle in the anterior hypothalamic area; major source of oxytocin and to a lesser extent, of antidiuretic hormone, neurohormones, which are carried to the neurohypophysis along the paraventriculohypophysial tract. (CSP). http://purl.obolibrary.org/obo/GO_0009749 response to glucose http://purl.obolibrary.org/obo/GO_0009746 response to hexose Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus. http://purl.obolibrary.org/obo/UBERON_0001932 arcuate nucleus of hypothalamus http://purl.obolibrary.org/obo/UBERON_0006568 hypothalamic nucleus The arcuate nucleus (or infundibular nucleus) is an aggregation of neurons in the mediobasal hypothalamus, adjacent to the third ventricle and the median eminence. The arcuate nucleus includes several important populations of neurons, including: Neuroendocrine neurons, Centrally-projecting neurons and Others. [WP,unvetted]. http://purl.obolibrary.org/obo/GO_0009786 regulation of asymmetric cell division http://purl.obolibrary.org/obo/GO_0051302 regulation of cell division Any process that modulates the frequency, rate or extent of asymmetric cell division. http://purl.obolibrary.org/obo/UBERON_0001943 midbrain tegmentum http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain Ventral part of the midbrain, separated from the hindbrain by the isthmus[ISBN:0471888893]. Subdivision of the midbrain lying anterior to the tectum and posterior to the substantia nigra and cerebral peduncle[FMA] The part of the midbrain extending from the substantia nigra to the cerebral aqueduct in a horizontal section of the midbrain. It forms the floor of the midbrain that surrounds the cerebral aqueduct[WP]. http://purl.obolibrary.org/obo/GO_0009790 embryo development http://purl.obolibrary.org/obo/GO_0007275 multicellular organism development The process whose specific outcome is the progression of an embryo from its formation until the end of its embryonic life stage. The end of the embryonic stage is organism-specific. For example, for mammals, the process would begin with zygote formation and end with birth. For insects, the process would begin at zygote formation and end with larval hatching. For plant zygotic embryos, this would be from zygote formation to the end of seed dormancy. For plant vegetative embryos, this would be from the initial determination of the cell or group of cells to form an embryo until the point when the embryo becomes independent of the parent plant. http://purl.obolibrary.org/obo/UBERON_0001944 pretectal region http://purl.obolibrary.org/obo/UBERON_0007245 nuclear complex of neuraxis Nuclear complex between dorsal thalamus and optic tectum whose nuclei receive afferents primarily from the retina and the optic tectum and are involved in modulating motor behavior in response to visual input. http://purl.obolibrary.org/obo/GO_0009889 regulation of biosynthetic process http://purl.obolibrary.org/obo/GO_0019222 regulation of metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances. http://purl.obolibrary.org/obo/UBERON_0001948 regional part of spinal cord http://purl.obolibrary.org/obo/UBERON_0000073 regional part of nervous system A multi-tissue structure that is part of a spinal cord. http://purl.obolibrary.org/obo/GO_0009890 negative regulation of biosynthetic process http://purl.obolibrary.org/obo/GO_0009892 negative regulation of metabolic process Any process that stops, prevents, or reduces the rate of the chemical reactions and pathways resulting in the formation of substances. http://purl.obolibrary.org/obo/UBERON_0001949 gingival epithelium http://purl.obolibrary.org/obo/UBERON_0035037 jaw epithelium A stratified squamous epithelium consisting of a basal layer; it is keratinized or parakeratinized[BTO]. http://purl.obolibrary.org/obo/GO_0009891 positive regulation of biosynthetic process http://purl.obolibrary.org/obo/GO_0009893 positive regulation of metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances. http://purl.obolibrary.org/obo/UBERON_0001950 neocortex http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain An area of cerebral cortex defined on the basis of cytoarchitecture that have six layers. Starting from the cortical surface the layers are: molecular layer (I), external granular layer (II), external pyramidal layer (III), internal granular layer (IV), internal pyramidal layer (V), and multiform layer (VI). Neocortex is most prominent in the frontal lobe, the parietal lobe, the temporal lobe and the occipital lobe, less so in the cingulate gyrus, the parahippocampal gyrus and the insula. It is composed of two subdivisions: true isocortex and proisocortex (Carpenter-83)(NN). http://purl.obolibrary.org/obo/GO_0009892 negative regulation of metabolic process http://purl.obolibrary.org/obo/GO_0019222 regulation of metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism. http://purl.obolibrary.org/obo/UBERON_0001951 epithelium of nasopharynx http://purl.obolibrary.org/obo/UBERON_0004814 upper respiratory tract epithelium An epithelium that is part of a nasopharynx [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0009893 positive regulation of metabolic process http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism. http://purl.obolibrary.org/obo/UBERON_0001954 Ammon's horn http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain A part of the brain consisting of a three layered cortex located in the forebrain bordering the medial surface of the lateral ventricle. The term hippocampus is often used synonymously with hippocampal formation which consists of the hippocampus proper or Cornu Ammonis, the dentate gyrus and the subiculum. http://purl.obolibrary.org/obo/GO_0009894 regulation of catabolic process http://purl.obolibrary.org/obo/GO_0019222 regulation of metabolic process Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of substances. http://purl.obolibrary.org/obo/UBERON_0001955 epithelium of respiratory bronchiole http://purl.obolibrary.org/obo/UBERON_0002051 epithelium of bronchiole An epithelium that is part of a respiratory bronchiole [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0009895 negative regulation of catabolic process http://purl.obolibrary.org/obo/GO_0009894 regulation of catabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances. http://purl.obolibrary.org/obo/UBERON_0001956 cartilage of bronchus http://purl.obolibrary.org/obo/UBERON_0003603 lower respiratory tract cartilage The hyaline cartilaginous structures that support the bronchi, present as irregular rings in the larger bronchi (and not as regular as in the trachea), and as small plates and islands in the smaller bronchi; as the branching continues through the bronchial tree, the amount of hyaline cartilage in the walls decreases until it is absent in the smallest bronchioles[MP]. http://purl.obolibrary.org/obo/GO_0009896 positive regulation of catabolic process http://purl.obolibrary.org/obo/GO_0009894 regulation of catabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances. http://purl.obolibrary.org/obo/UBERON_0001957 submucosa of bronchus http://purl.obolibrary.org/obo/UBERON_0004777 respiratory system submucosa A submucosa that is part of a bronchus [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0009902 chloroplast relocation http://purl.obolibrary.org/obo/GO_0051667 establishment of plastid localization The process in which chloroplasts in photosynthetic cells migrate toward illuminated sites to optimize photosynthesis and move away from excessively illuminated areas to protect the photosynthetic machinery. http://purl.obolibrary.org/obo/UBERON_0001958 terminal bronchiole epithelium http://purl.obolibrary.org/obo/UBERON_0002051 epithelium of bronchiole An epithelium that lines a terminal bronchiole. http://purl.obolibrary.org/obo/GO_0009941 chloroplast envelope http://purl.obolibrary.org/obo/GO_0009526 plastid envelope The double lipid bilayer enclosing the chloroplast and separating its contents from the rest of the cytoplasm; includes the intermembrane space. http://purl.obolibrary.org/obo/UBERON_0001959 white pulp of spleen http://purl.obolibrary.org/obo/UBERON_1000023 spleen pulp The parenchymatous tissue of the spleen that surrounds splenic blood vessels, consists of compact masses of lymphatic cells and is where foreign material removed from the blood is used to initiate an immune reaction that results in the production of antibodies. http://purl.obolibrary.org/obo/GO_0009977 proton motive force dependent protein transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0008320 protein transmembrane transporter activity Catalysis of the transfer of proteins from one side of a membrane to the other. Transportation is dependent on pH gradient across the membrane. http://purl.obolibrary.org/obo/UBERON_0001960 periarterial lymphatic sheath http://purl.obolibrary.org/obo/UBERON_0010393 T cell domain The area of the spleen in which T cells surround the central arteriole. http://purl.obolibrary.org/obo/GO_0009992 intracellular water homeostasis http://purl.obolibrary.org/obo/GO_0055082 intracellular chemical homeostasis A homeostatic process involved in the maintenance of a steady state level of water within a cell. http://purl.obolibrary.org/obo/UBERON_0001962 gut-associated lymphoid tissue http://purl.obolibrary.org/obo/UBERON_0001961 mucosa-associated lymphoid tissue Mucosa-associated lymphoid tissue in digestive tract. includes Peyer's patches, appendix, and solitary lymph nodules[GO]. http://purl.obolibrary.org/obo/GO_0009994 oocyte differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized immature germ cell acquires the specialized features of a mature female gamete. http://purl.obolibrary.org/obo/UBERON_0001963 bronchial-associated lymphoid tissue http://purl.obolibrary.org/obo/UBERON_0001961 mucosa-associated lymphoid tissue A diffuse collection of lymphpoid cells that participate in airway immune responses. http://purl.obolibrary.org/obo/GO_0010020 chloroplast fission http://purl.obolibrary.org/obo/GO_0043572 plastid fission The division of a chloroplast within a cell to form two or more separate chloroplast compartments. This division occurs independently of mitosis. http://purl.obolibrary.org/obo/UBERON_0001968 semen http://purl.obolibrary.org/obo/UBERON_0000463 organism substance Organism substance that is composed of sperm cells suspended in seminal fluid. http://purl.obolibrary.org/obo/UBERON_0001969 blood plasma http://purl.obolibrary.org/obo/UBERON_0000179 haemolymphatic fluid The liquid component of blood, in which erythrocytes are suspended. http://purl.obolibrary.org/obo/GO_0010032 meiotic chromosome condensation http://purl.obolibrary.org/obo/GO_0030261 chromosome condensation Compaction of chromatin structure prior to meiosis in eukaryotic cells. http://purl.obolibrary.org/obo/UBERON_0001970 bile http://purl.obolibrary.org/obo/UBERON_0006314 bodily fluid Vital aqueous secretion of the liver that is formed by hepatocytes and modified down stream by absorptive and secretory properties of the bile duct epithelium. http://purl.obolibrary.org/obo/GO_0010038 response to metal ion http://purl.obolibrary.org/obo/GO_0042221 response to chemical Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metal ion stimulus. http://purl.obolibrary.org/obo/UBERON_0001972 submucosa of esophagus http://purl.obolibrary.org/obo/UBERON_0018257 submucosa of digestive tract A submucosa that is part of a esophagus [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0010039 response to iron ion http://purl.obolibrary.org/obo/GO_0010038 response to metal ion Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron ion stimulus. http://purl.obolibrary.org/obo/UBERON_0001974 lamina propria of esophagus http://purl.obolibrary.org/obo/UBERON_0000030 lamina propria A lamina propria that is part of a esophagus [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0010070 zygote asymmetric cell division http://purl.obolibrary.org/obo/GO_0008356 asymmetric cell division The division of the zygote into two daughter cells that will adopt developmentally distinct potentials. http://purl.obolibrary.org/obo/UBERON_0001975 serosa of esophagus http://purl.obolibrary.org/obo/UBERON_0000042 serous membrane A serous membrane that is part of a esophagus [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0010109 regulation of photosynthesis http://purl.obolibrary.org/obo/GO_0019222 regulation of metabolic process Any process that modulates the frequency, rate or extent of photosynthesis. http://purl.obolibrary.org/obo/UBERON_0001976 epithelium of esophagus http://purl.obolibrary.org/obo/UBERON_0003929 digestive tract epithelium The epithelial layer that lines the luminal space of the esophagus. http://purl.obolibrary.org/obo/GO_0010155 regulation of proton transport http://purl.obolibrary.org/obo/GO_1904062 regulation of monoatomic cation transmembrane transport Any process that modulates the frequency, rate or extent of proton transport into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/UBERON_0001979 venule http://purl.obolibrary.org/obo/UBERON_8410081 blood microvessel One of the minute vessels that collect deoxygenated blood from the capillary plexuses returns it to the veins. http://purl.obolibrary.org/obo/GO_0010171 body morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structures of the soma are generated and organized. http://purl.obolibrary.org/obo/UBERON_0001980 arteriole http://purl.obolibrary.org/obo/UBERON_8410081 blood microvessel The smallest division of the artery located between the muscular arteries and the capillaries[GO]. http://purl.obolibrary.org/obo/UBERON_0001981 blood vessel http://purl.obolibrary.org/obo/UBERON_0000055 vessel A vessel through which blood circulates in the body. http://purl.obolibrary.org/obo/UBERON_0001983 crypt of Lieberkuhn http://purl.obolibrary.org/obo/UBERON_0000333 intestinal gland The tubular intestinal glands found in the mucosal membranes. http://purl.obolibrary.org/obo/UBERON_0001984 crypt of Lieberkuhn of large intestine http://purl.obolibrary.org/obo/UBERON_0001983 crypt of Lieberkuhn A crypt of Lieberkühn that is part of a large intestine [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0001985 corneal endothelium http://purl.obolibrary.org/obo/UBERON_0015808 eye epithelium A monolayer of specialized, flattened, mitochondria-rich cells that lines the posterior surface of the cornea and faces the anterior chamber of the eye[WP]. http://purl.obolibrary.org/obo/UBERON_0001986 endothelium http://purl.obolibrary.org/obo/UBERON_0012275 meso-epithelium A layer of epithelium that lines the heart, blood vessels (endothelium, vascular), lymph vessels (endothelium, lymphatic), and the serous cavities of the body[MESH]. Simple squamous epithelium which lines blood and lymphatic vessels and the heart[FMA]. http://purl.obolibrary.org/obo/UBERON_0001988 feces http://purl.obolibrary.org/obo/UBERON_0000174 excreta Portion of semisolid bodily waste discharged through the anus[MW,modified]. http://purl.obolibrary.org/obo/UBERON_0001989 superior cervical ganglion http://purl.obolibrary.org/obo/UBERON_0001991 cervical ganglion Trunk ganglion which is bilaterally paired and located at the anterior end of the sympathetic ganglion chain. http://purl.obolibrary.org/obo/UBERON_0001990 middle cervical ganglion http://purl.obolibrary.org/obo/UBERON_0001991 cervical ganglion The small ganglion located at the level of the cricoid cartilage of the laryngeal wall. http://purl.obolibrary.org/obo/UBERON_0001991 cervical ganglion http://purl.obolibrary.org/obo/UBERON_0001807 paravertebral ganglion The cervical ganglia are paravertebral ganglia of the sympathetic nervous system. They consist of three paravertebral ganglia: superior cervical ganglion middle cervical ganglion inferior cervical ganglion. The inferior ganglion may be fused with the first thoracic ganglion to form a single structure, the stellate ganglion. Nerves emerging from cervical sympathetic ganglia contribute to the cardiac plexus, among other things. [WP,unvetted]. http://purl.obolibrary.org/obo/UBERON_0001992 papillary layer of dermis http://purl.obolibrary.org/obo/UBERON_0013754 integumentary system layer The upper layer of the dermis beneath the epidermis, composed of dense irregular connective tissue[ncit,modified]. http://purl.obolibrary.org/obo/UBERON_0001993 reticular layer of dermis http://purl.obolibrary.org/obo/UBERON_0013754 integumentary system layer The thicker, deeper layer of the dermis, comprised of criss-crossing collagen fibers that form a strong elastic network and also containing blood and lymph vessels, nerves and nerve endings, and hair follicles. http://purl.obolibrary.org/obo/UBERON_0001994 hyaline cartilage tissue http://purl.obolibrary.org/obo/UBERON_0002418 cartilage tissue Cartilage tissue primarily composed of type II collagen (thin fibrils) and a glassy appearance. http://purl.obolibrary.org/obo/UBERON_0001995 fibrocartilage http://purl.obolibrary.org/obo/UBERON_0002418 cartilage tissue Cartilage tissue intermediate between hyaline cartilage and dense connective tissue; contains of abundant collagen fibers; chondrocytes often arranged in columns. http://purl.obolibrary.org/obo/UBERON_0001996 elastic cartilage tissue http://purl.obolibrary.org/obo/UBERON_0011589 non-mineralized cartilage tissue Cartilage tissue that is flexible and contains abundant elastic fibers. http://purl.obolibrary.org/obo/UBERON_0001997 olfactory epithelium http://purl.obolibrary.org/obo/UBERON_0010371 ecto-epithelium A sensory epithelium inside the nasal cavity that is responsible for detecting odors[WP]. http://purl.obolibrary.org/obo/UBERON_0002001 joint of rib http://purl.obolibrary.org/obo/UBERON_0000982 skeletal joint Any joint that connects a rib to another structure (or another rib). Examples: costochondral, costovertebral, interchondral, sternocostal joints. http://purl.obolibrary.org/obo/UBERON_0002005 enteric nervous system http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision The enteric nervous system is composed of two ganglionated neural plexuses in the gut wall which form one of the three major divisions of the autonomic nervous system. The enteric nervous system innervates the gastrointestinal tract, the pancreas, and the gall bladder. It contains sensory neurons, interneurons, and motor neurons. Thus the circuitry can autonomously sense the tension and the chemical environment in the gut and regulate blood vessel tone, motility, secretions, and fluid transport. The system is itself governed by the central nervous system and receives both parasympathetic and sympathetic innervation[GO]. http://purl.obolibrary.org/obo/UBERON_0002006 cortex of lymph node http://purl.obolibrary.org/obo/UBERON_0001851 cortex Peripheral portion of the lymph node, underneath the capsule[WP]. http://purl.obolibrary.org/obo/UBERON_0002007 medulla of lymph node http://purl.obolibrary.org/obo/UBERON_0000958 medulla of organ The medullary portion of the lymph node, which contains large blood vessels, sinuses and medullary cords that contain antibody-secreting plasma cells. http://purl.obolibrary.org/obo/UBERON_0002008 cardiac nerve plexus http://purl.obolibrary.org/obo/UBERON_0001816 autonomic nerve plexus A plexus of nerves situated at the base of the heart that innervate the heart. http://purl.obolibrary.org/obo/GO_0010232 vascular transport http://purl.obolibrary.org/obo/GO_0003018 vascular process in circulatory system The directed movement of substances, into, out of or within a cell, either in a vascular tissue or in the vascular membrane. http://purl.obolibrary.org/obo/UBERON_0002010 celiac nerve plexus http://purl.obolibrary.org/obo/UBERON_0001816 autonomic nerve plexus A complex network of nerves located in the abdomen behind the stomach. The celiac plexus is located near where the celiac trunk, superior mesenteric artery, and renal arteries branch from the abdominal aorta. It is behind the stomach and the omental bursa and in front of the crura of the diaphragm, on the level of the first lumbar vertebra, L1. The plexus is formed (in part) by the greater and lesser splanchnic nerves of both sides, and also parts of the right vagus nerve. The celiac plexus proper consists of the celiac ganglia with a network of interconnecting fibers. The aorticorenal ganglia are often considered to be part of the celiac ganglia, and thus, part of the plexus. [WP,unvetted]. http://purl.obolibrary.org/obo/GO_0010453 regulation of cell fate commitment http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field. http://purl.obolibrary.org/obo/UBERON_0002011 thoracodorsal artery http://purl.obolibrary.org/obo/UBERON_0001637 artery The thoracodorsal artery is a branch of the subscapular artery. It travels inferiorly with the thoracodorsal nerve and supplies the latissimus dorsi. [WP,unvetted]. http://purl.obolibrary.org/obo/GO_0010454 negative regulation of cell fate commitment http://purl.obolibrary.org/obo/GO_0010453 regulation of cell fate commitment Any process that stops, prevents or reduces the frequency or rate of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field. http://purl.obolibrary.org/obo/UBERON_0002015 kidney capsule http://purl.obolibrary.org/obo/UBERON_0011824 fibrous connective tissue The tough fibrous layer surrounding the kidney which is covered in a thick layer of perirenal adipose tissue that functions to provide some protection from trauma and damage. http://purl.obolibrary.org/obo/GO_0010455 positive regulation of cell fate commitment http://purl.obolibrary.org/obo/GO_0045597 positive regulation of cell differentiation Any process that activates, maintains or increases the frequency or rate of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field. http://purl.obolibrary.org/obo/UBERON_0002017 portal vein http://purl.obolibrary.org/obo/UBERON_0001638 vein A vein that conducts blood from the digestive organs, spleen, pancreas, and gallbladder to the liver[BTO]. http://purl.obolibrary.org/obo/GO_0010456 cell proliferation in dorsal spinal cord http://purl.obolibrary.org/obo/GO_0061351 neural precursor cell proliferation The multiplication or reproduction of cells, resulting in the expansion of the dorsal spinal cord cell population. http://purl.obolibrary.org/obo/UBERON_0002018 synovial membrane of synovial joint http://purl.obolibrary.org/obo/UBERON_0007616 layer of synovial tissue Soft tissue that lines the non-cartilaginous surfaces within joints with cavities (synovial joints). http://purl.obolibrary.org/obo/GO_0010470 regulation of gastrulation http://purl.obolibrary.org/obo/GO_0045995 regulation of embryonic development Any process that modulates the rate or extent of gastrulation. Gastrulation is the complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals. http://purl.obolibrary.org/obo/UBERON_0002020 gray matter http://purl.obolibrary.org/obo/UBERON_0011215 central nervous system cell part cluster A nervous system structure composed primarily of nerve cell bodies (somas). May also include dendrites and the initial unmyelinated portion of axons. http://purl.obolibrary.org/obo/GO_0010481 epidermal cell division http://purl.obolibrary.org/obo/GO_0051301 cell division Any process resulting in the physical partitioning and separation of an epidermal cell, any of the cells making up the epidermis, into daughter cells. http://purl.obolibrary.org/obo/UBERON_0002025 stratum basale of epidermis http://purl.obolibrary.org/obo/UBERON_0013754 integumentary system layer The deepest layer of the epidermis, which is composed of dividing stem cells and anchoring cells. http://purl.obolibrary.org/obo/GO_0010482 regulation of epidermal cell division http://purl.obolibrary.org/obo/GO_0051302 regulation of cell division Any process that modulates the frequency, rate or extent of the physical partitioning and separation of an epidermal cell into daughter cells. An epidermal cell is any of the cells that make up the epidermis. http://purl.obolibrary.org/obo/GO_0010496 intercellular transport http://purl.obolibrary.org/obo/GO_0009987 cellular process The movement of substances between cells. http://purl.obolibrary.org/obo/UBERON_0002026 stratum spinosum of epidermis http://purl.obolibrary.org/obo/UBERON_0013754 integumentary system layer The layer of polyhedral cells in the epidermis found between the stratum granulosum and stratum basale; shrinkage and adhesion of these cells gives a spiny or prickly appearance. http://purl.obolibrary.org/obo/GO_0010543 regulation of platelet activation http://purl.obolibrary.org/obo/GO_0050865 regulation of cell activation Any process that modulates the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. http://purl.obolibrary.org/obo/UBERON_0002027 stratum corneum of epidermis http://purl.obolibrary.org/obo/UBERON_0013754 integumentary system layer The outer layer of the epidermis, consisting of several layers of flat keratinized non-nucleated cells. http://purl.obolibrary.org/obo/GO_0010544 negative regulation of platelet activation http://purl.obolibrary.org/obo/GO_0030195 negative regulation of blood coagulation Any process that decreases the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. http://purl.obolibrary.org/obo/UBERON_0002028 hindbrain http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure The most posterior of the three principal regions of the brain. In mammals and birds the hindbrain is divided into a rostral metencephalon and a caudal myelencephalon. In zebrafish, with the exception of the cerebellum, the ventral remainder of the metencephalon can be separated only arbitrarily from the more caudal myelencephalic portion of the medulla oblongata (From: Neuroanatomy of the Zebrafish Brain)[ZFA]. Organ component of neuraxis that has as its parts the pons, cerebellum and medulla oblongata[FMA]. http://purl.obolibrary.org/obo/GO_0010549 regulation of membrane disassembly http://purl.obolibrary.org/obo/GO_0051128 regulation of cellular component organization Any process that modulates the frequency, rate or extent of membrane disassembly. http://purl.obolibrary.org/obo/UBERON_0002029 epithelium of gall bladder http://purl.obolibrary.org/obo/UBERON_0034932 epithelium of biliary system The simple columnar epithelial lining of the gall bladder. http://purl.obolibrary.org/obo/GO_0010559 regulation of glycoprotein biosynthetic process http://purl.obolibrary.org/obo/GO_1903018 regulation of glycoprotein metabolic process Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide. http://purl.obolibrary.org/obo/UBERON_0002031 epithelium of bronchus http://purl.obolibrary.org/obo/UBERON_0008397 tracheobronchial epithelium An epithelium that is part of a bronchus [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0010560 positive regulation of glycoprotein biosynthetic process http://purl.obolibrary.org/obo/GO_1903020 positive regulation of glycoprotein metabolic process Any process that increases the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide. http://purl.obolibrary.org/obo/UBERON_0002033 arrector muscle of hair http://purl.obolibrary.org/obo/UBERON_0001135 smooth muscle tissue A tiny smooth muscle that connects the hair follicle with the dermis. http://purl.obolibrary.org/obo/GO_0010561 negative regulation of glycoprotein biosynthetic process http://purl.obolibrary.org/obo/GO_1903019 negative regulation of glycoprotein metabolic process Any process that decreases the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide. http://purl.obolibrary.org/obo/UBERON_0002034 suprachiasmatic nucleus http://purl.obolibrary.org/obo/UBERON_0007251 preoptic nucleus * An ovoid densely packed collection of small cells of the anterior hypothalamus lying close to the midline in a shallow impression of the optic chiasm. (MSH) * small group of nerve cell bodies in the supraoptic region of the hypothalamus, just above the optic chiasm; influences rhythmic aspects of hypothalamic functions in many vertebrate species. (CSP). http://purl.obolibrary.org/obo/GO_0010562 positive regulation of phosphorus metabolic process http://purl.obolibrary.org/obo/GO_0051174 regulation of phosphorus metabolic process Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus. http://purl.obolibrary.org/obo/UBERON_0002036 striated muscle tissue http://purl.obolibrary.org/obo/UBERON_0002385 muscle tissue Muscle tissue that contains fibers that are divided by transverse bands into striations. http://purl.obolibrary.org/obo/GO_0010563 negative regulation of phosphorus metabolic process http://purl.obolibrary.org/obo/GO_0051174 regulation of phosphorus metabolic process Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus. http://purl.obolibrary.org/obo/UBERON_0002038 substantia nigra http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure Predominantly gray matter midbrain structure lying dorsal to the crus cerebri and ventral to the midbrain tegmentum. It is divided into a dorsal, cellularly compact region known as the pars compacta and a more ventrally located, containing more loosely packed cells, the pars reticulata. The most lateral region of the reticulata is identified as the pars lateralis (MM). http://purl.obolibrary.org/obo/GO_0010567 regulation of ketone catabolic process http://purl.obolibrary.org/obo/GO_0009894 regulation of catabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a ketone, carried out by individual cells. http://purl.obolibrary.org/obo/UBERON_0002040 bronchial artery http://purl.obolibrary.org/obo/UBERON_0004573 systemic artery A systemic artery that supplies the lung with with oxygenated blood. http://purl.obolibrary.org/obo/UBERON_0002042 lymphatic vessel endothelium http://purl.obolibrary.org/obo/UBERON_0004852 cardiovascular system endothelium An endothelium that is part of a lymphatic vessel [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0010572 positive regulation of platelet activation http://purl.obolibrary.org/obo/GO_0010543 regulation of platelet activation Any process that increases the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. http://purl.obolibrary.org/obo/UBERON_0002047 pontine raphe nucleus http://purl.obolibrary.org/obo/UBERON_0009662 hindbrain nucleus The pontine raphe nucleus is one of the raphe nuclei. It is located in the pontine tegmentum. [WP,unvetted]. http://purl.obolibrary.org/obo/GO_0010581 regulation of starch biosynthetic process http://purl.obolibrary.org/obo/GO_2000904 regulation of starch metabolic process An process which modulate the frequency, rate or extent of starch biosynthesis, the chemical reactions and pathways resulting in the formation of starch. http://purl.obolibrary.org/obo/UBERON_0002049 vasculature http://purl.obolibrary.org/obo/UBERON_0000477 anatomical cluster An interconnected tubular multi-tissue structure contains fluid that is actively transported around the organism[ZFA]. Examples: vasculature of lung, vasculature of face. http://purl.obolibrary.org/obo/GO_0010594 regulation of endothelial cell migration http://purl.obolibrary.org/obo/GO_0030334 regulation of cell migration Any process that modulates the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium. http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure Anatomical structure that is part of an embryo. http://purl.obolibrary.org/obo/GO_0010595 positive regulation of endothelial cell migration http://purl.obolibrary.org/obo/GO_0010594 regulation of endothelial cell migration Any process that increases the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium. http://purl.obolibrary.org/obo/UBERON_0002051 epithelium of bronchiole http://purl.obolibrary.org/obo/UBERON_0008397 tracheobronchial epithelium An epithelium that is part of a bronchiole [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0010596 negative regulation of endothelial cell migration http://purl.obolibrary.org/obo/GO_0010594 regulation of endothelial cell migration Any process that decreases the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium. http://purl.obolibrary.org/obo/UBERON_0002052 adrenal gland capsule http://purl.obolibrary.org/obo/UBERON_0003893 capsule The thick capsule of dense irregular connective tissue that surrounds each adrenal gland and contains scattered elastic fibers; the capsule contains a rich plexus of blood vessels (mainly small arteries) and numerous nerve fibers; some blood vessels and nerves enter the substance of the gland in the trabeculae that extend inward from the capsule and then leave the trabeculae to enter the cortex. http://purl.obolibrary.org/obo/GO_0010611 regulation of cardiac muscle hypertrophy http://purl.obolibrary.org/obo/GO_0043502 regulation of muscle adaptation Any process that modulates the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division. http://purl.obolibrary.org/obo/UBERON_0002053 zona glomerulosa of adrenal gland http://purl.obolibrary.org/obo/UBERON_0009753 adrenal gland cortex zone The narrow subcapsular outer zone of the adrenal cortex where aldosterone is produced. http://purl.obolibrary.org/obo/GO_0010612 regulation of cardiac muscle adaptation http://purl.obolibrary.org/obo/GO_0043502 regulation of muscle adaptation Any process that modulates the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. http://purl.obolibrary.org/obo/UBERON_0002056 inferior suprarenal artery http://purl.obolibrary.org/obo/UBERON_0005624 suprarenal artery Each renal artery gives off some small inferior suprarenal branches to the suprarenal gland, the ureter, and the surrounding cellular tissue and muscles. [WP,unvetted]. http://purl.obolibrary.org/obo/GO_0010613 positive regulation of cardiac muscle hypertrophy http://purl.obolibrary.org/obo/GO_0014742 positive regulation of muscle hypertrophy Any process that increases the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division. http://purl.obolibrary.org/obo/UBERON_0002057 phrenic artery http://purl.obolibrary.org/obo/UBERON_0004573 systemic artery An artery that supplies the diaphragm. http://purl.obolibrary.org/obo/GO_0010614 negative regulation of cardiac muscle hypertrophy http://purl.obolibrary.org/obo/GO_0014741 negative regulation of muscle hypertrophy Any process that decreases the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division. http://purl.obolibrary.org/obo/UBERON_0002058 main ciliary ganglion http://purl.obolibrary.org/obo/UBERON_0001714 cranial ganglion A parasympathetic ganglion located in the posterior orbit that contains preganglionic nerves and postganglionic neurons of the oculomotor nerve, connects to the Edinger-Westphal nucleus via the oculomotor nerve and the eye muscles via the short ciliary nerve. http://purl.obolibrary.org/obo/GO_0010615 positive regulation of cardiac muscle adaptation http://purl.obolibrary.org/obo/GO_0014744 positive regulation of muscle adaptation Any process that increases the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. http://purl.obolibrary.org/obo/UBERON_0002059 submandibular ganglion http://purl.obolibrary.org/obo/UBERON_0001808 parasympathetic ganglion The ganglion associated with the lingual nerve that provides postsynaptic fibers to the submandibular and sublingual glands. http://purl.obolibrary.org/obo/GO_0010616 negative regulation of cardiac muscle adaptation http://purl.obolibrary.org/obo/GO_0014745 negative regulation of muscle adaptation Any process that decreases the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. http://purl.obolibrary.org/obo/UBERON_0002060 femoral artery http://purl.obolibrary.org/obo/UBERON_0001637 artery The femoral artery is a large artery in the muscles of the thigh. It is a continuation of external iliac artery where it enters the femoral triangle at the mid inguinal point behind the inguinal ligament. It leaves femoral triangle through apex beneath the sartorius muscle. It enters the popliteal fossa by passing through the 5th osseo-aponeurotic(adductor hiatus) opening of adductor magnus where it becomes the Popliteal Artery. [WP,unvetted]. http://purl.obolibrary.org/obo/GO_0010623 programmed cell death involved in cell development http://purl.obolibrary.org/obo/GO_0048869 cellular developmental process The activation of endogenous cellular processes that result in the death of a cell as part of its development. http://purl.obolibrary.org/obo/UBERON_0002061 truncus arteriosus http://purl.obolibrary.org/obo/UBERON_0003498 heart blood vessel The truncus arteriosus and bulbus cordis are divided by the aorticopulmonary septum. The truncus arteriosus gives rise to the ascending aorta and the pulmonary trunk. The bulbus cordis gives rise to the smooth parts (outflow tract) of the left and right ventricles. http://purl.obolibrary.org/obo/GO_0010624 regulation of Schwann cell proliferation http://purl.obolibrary.org/obo/GO_0060251 regulation of glial cell proliferation Any process that modulates the frequency or rate of multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system. http://purl.obolibrary.org/obo/GO_0010625 positive regulation of Schwann cell proliferation http://purl.obolibrary.org/obo/GO_0060252 positive regulation of glial cell proliferation Any process that increases the frequency or rate of the multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system. http://purl.obolibrary.org/obo/UBERON_0002062 endocardial cushion http://purl.obolibrary.org/obo/UBERON_0014387 mesenchyme derived from neural crest The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves[GO]. Swellings of tissue present between the endocardial and myocardial cell layers that will give rise to the interstitial cells of the cardiac valves[ZFA]. http://purl.obolibrary.org/obo/GO_0010626 negative regulation of Schwann cell proliferation http://purl.obolibrary.org/obo/GO_0060253 negative regulation of glial cell proliferation Any process that decreases the frequency or extent of the multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system. http://purl.obolibrary.org/obo/UBERON_0002063 sinus venosus http://purl.obolibrary.org/obo/UBERON_0004151 cardiac chamber The sinus venosus is a large cardiac chamber at the inflow tract that receives venous blood from systemic circulation. precedes the atrium on the venous side of the chordate heart. http://purl.obolibrary.org/obo/GO_0010628 positive regulation of gene expression http://purl.obolibrary.org/obo/GO_0010557 positive regulation of macromolecule biosynthetic process Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA). http://purl.obolibrary.org/obo/UBERON_0002066 umbilical vein http://purl.obolibrary.org/obo/UBERON_0010260 umbilical blood vessel The umbilical vein is a blood vessel present during fetal development that carries oxygenated blood from the placenta to the growing fetus. [WP,unvetted]. http://purl.obolibrary.org/obo/GO_0010632 regulation of epithelial cell migration http://purl.obolibrary.org/obo/GO_0051239 regulation of multicellular organismal process Any process that modulates the frequency, rate or extent of epithelial cell migration. http://purl.obolibrary.org/obo/UBERON_0002069 stratum granulosum of epidermis http://purl.obolibrary.org/obo/UBERON_0013754 integumentary system layer The layer of flattened cells containing basophilic granules of keratohyalin and lying just above the stratum spinosum (spiny layer) of the epidermis. http://purl.obolibrary.org/obo/GO_0010633 negative regulation of epithelial cell migration http://purl.obolibrary.org/obo/GO_0010632 regulation of epithelial cell migration Any process that stops, prevents, or reduces the frequency, rate or extent of epithelial cell migration. http://purl.obolibrary.org/obo/UBERON_0002072 hypodermis http://purl.obolibrary.org/obo/UBERON_0013754 integumentary system layer Lowermost layer of the integumentary system in vertebrates. Types of cells that are found in the hypodermis are fibroblasts, adipose cells, and macrophages. It is derived from the mesoderm, but unlike the dermis, it is not derived from the dermatome region of the mesoderm. The hypodermis is used mainly for fat storage[WP]. http://purl.obolibrary.org/obo/GO_0010634 positive regulation of epithelial cell migration http://purl.obolibrary.org/obo/GO_0010632 regulation of epithelial cell migration Any process that activates or increases the frequency, rate or extent of epithelial cell migration. http://purl.obolibrary.org/obo/UBERON_0002073 hair follicle http://purl.obolibrary.org/obo/UBERON_0036150 skin appendage follicle A tube-like opening in the epidermis where the hair shaft develops and into which the sebaceous glands open[GO]. http://purl.obolibrary.org/obo/GO_0010635 regulation of mitochondrial fusion http://purl.obolibrary.org/obo/GO_0010821 regulation of mitochondrion organization Any process that modulates the frequency, rate or extent of merging of two or more mitochondria within a cell to form a single compartment. http://purl.obolibrary.org/obo/UBERON_0002074 hair shaft http://purl.obolibrary.org/obo/UBERON_0000021 cutaneous appendage The main part of the hair which is composed of trichocytes and is divided into the cortex and medulla. http://purl.obolibrary.org/obo/GO_0010636 positive regulation of mitochondrial fusion http://purl.obolibrary.org/obo/GO_0010638 positive regulation of organelle organization Any process that increases the frequency, rate or extent of merging of two or more mitochondria within a cell to form a single compartment. http://purl.obolibrary.org/obo/UBERON_0002075 viscus http://purl.obolibrary.org/obo/UBERON_0005177 trunk region element An organ that is located within the body cavity (or in its extension, in the scrotum); it consists of organ parts that are embryologically derived from endoderm, splanchnic mesoderm or intermediate mesoderm; together with other organs, the viscus constitutes the respiratory, gastrointestinal, urinary, reproductive and immune systems, or is the central organ of the cardiovascular system. Examples: heart, lung, esophagus, kidney, ovary, spleen. http://purl.obolibrary.org/obo/GO_0010637 negative regulation of mitochondrial fusion http://purl.obolibrary.org/obo/GO_0010639 negative regulation of organelle organization Any process that decreases the frequency, rate or extent of merging of two or more mitochondria within a cell to form a single compartment. http://purl.obolibrary.org/obo/UBERON_0002076 cuticle of hair http://purl.obolibrary.org/obo/UBERON_0000119 cell layer Smooth and glossy outer protective cell layer of hair shaft. http://purl.obolibrary.org/obo/GO_0010638 positive regulation of organelle organization http://purl.obolibrary.org/obo/GO_0051130 positive regulation of cellular component organization Any process that increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle. http://purl.obolibrary.org/obo/GO_0010639 negative regulation of organelle organization http://purl.obolibrary.org/obo/GO_0051129 negative regulation of cellular component organization Any process that decreases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle. http://purl.obolibrary.org/obo/UBERON_0002077 cortex of hair http://purl.obolibrary.org/obo/UBERON_0001851 cortex A cortex that is part of a hair [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0010647 positive regulation of cell communication http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that increases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. http://purl.obolibrary.org/obo/GO_0010648 negative regulation of cell communication http://purl.obolibrary.org/obo/GO_0010646 regulation of cell communication Any process that decreases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. http://purl.obolibrary.org/obo/UBERON_0002078 right cardiac atrium http://purl.obolibrary.org/obo/UBERON_0035554 right cardiac chamber A cardiac atrium that is in the right side of the heart. It receives deoxygenated blood. In mammals, this comes from the superior and inferior vena cava and the coronary sinus, and pumps it into the right ventricle through the tricuspid valve. http://purl.obolibrary.org/obo/GO_0010656 negative regulation of muscle cell apoptotic process http://purl.obolibrary.org/obo/GO_0010660 regulation of muscle cell apoptotic process Any process that decreases the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death. http://purl.obolibrary.org/obo/GO_0010657 muscle cell apoptotic process http://purl.obolibrary.org/obo/GO_0006915 apoptotic process A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a muscle cell and result in its death. A muscle cell is a mature contractile cell, commonly known as a myocyte, that forms one of three kinds of muscle. http://purl.obolibrary.org/obo/UBERON_0002079 left cardiac atrium http://purl.obolibrary.org/obo/UBERON_0035553 left cardiac chamber A cardiac atrium that is in the left side of the heart. It receives oxygenated blood from the pulmonary veins, In mammals this is pumped into the left ventricle, via the Mitral valve. http://purl.obolibrary.org/obo/GO_0010658 striated muscle cell apoptotic process http://purl.obolibrary.org/obo/GO_0010657 muscle cell apoptotic process A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a striated muscle cell and result in its death. Striated muscle cells make up striated muscle fibers which are divided by transverse bands into striations. http://purl.obolibrary.org/obo/GO_0010659 cardiac muscle cell apoptotic process http://purl.obolibrary.org/obo/GO_0010658 striated muscle cell apoptotic process A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a cardiac muscle cell and result in its death. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. http://purl.obolibrary.org/obo/UBERON_0002080 heart right ventricle http://purl.obolibrary.org/obo/UBERON_0035554 right cardiac chamber A cardiac ventricle that is in the right side of the heart. http://purl.obolibrary.org/obo/GO_0010660 regulation of muscle cell apoptotic process http://purl.obolibrary.org/obo/GO_0042981 regulation of apoptotic process Any process that modulates the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death. http://purl.obolibrary.org/obo/GO_0010661 positive regulation of muscle cell apoptotic process http://purl.obolibrary.org/obo/GO_0043065 positive regulation of apoptotic process Any process that increases the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death. http://purl.obolibrary.org/obo/UBERON_0002081 cardiac atrium http://purl.obolibrary.org/obo/UBERON_0004151 cardiac chamber Cardiac chamber in which blood enters the heart. http://purl.obolibrary.org/obo/GO_0010662 regulation of striated muscle cell apoptotic process http://purl.obolibrary.org/obo/GO_0010660 regulation of muscle cell apoptotic process Any process that modulates the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death. http://purl.obolibrary.org/obo/GO_0010663 positive regulation of striated muscle cell apoptotic process http://purl.obolibrary.org/obo/GO_0010662 regulation of striated muscle cell apoptotic process Any process that increases the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death. http://purl.obolibrary.org/obo/UBERON_0002082 cardiac ventricle http://purl.obolibrary.org/obo/UBERON_0004151 cardiac chamber Cardiac chamber through which blood leaves the heart. http://purl.obolibrary.org/obo/GO_0010664 negative regulation of striated muscle cell apoptotic process http://purl.obolibrary.org/obo/GO_0010662 regulation of striated muscle cell apoptotic process Any process that decreases the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death. http://purl.obolibrary.org/obo/GO_0010665 regulation of cardiac muscle cell apoptotic process http://purl.obolibrary.org/obo/GO_0010662 regulation of striated muscle cell apoptotic process Any process that modulates the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death. http://purl.obolibrary.org/obo/UBERON_0002084 heart left ventricle http://purl.obolibrary.org/obo/UBERON_0035553 left cardiac chamber A cardiac ventricle that is in the left side of the heart. http://purl.obolibrary.org/obo/GO_0010666 positive regulation of cardiac muscle cell apoptotic process http://purl.obolibrary.org/obo/GO_0010665 regulation of cardiac muscle cell apoptotic process Any process that increases the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death. http://purl.obolibrary.org/obo/GO_0010667 negative regulation of cardiac muscle cell apoptotic process http://purl.obolibrary.org/obo/GO_0010665 regulation of cardiac muscle cell apoptotic process Any process that decreases the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death. http://purl.obolibrary.org/obo/GO_0010700 negative regulation of norepinephrine secretion http://purl.obolibrary.org/obo/GO_0033604 negative regulation of catecholamine secretion Any process that decreases the frequency, rate or extent of the regulated release of norepinephrine. http://purl.obolibrary.org/obo/UBERON_0002085 interatrial septum http://purl.obolibrary.org/obo/UBERON_0002099 cardiac septum A cardiac septum that divides the left and right atria of the heart. http://purl.obolibrary.org/obo/GO_0010701 positive regulation of norepinephrine secretion http://purl.obolibrary.org/obo/GO_0033605 positive regulation of catecholamine secretion Any process that increases the frequency, rate or extent of the regulated release of norepinephrine. http://purl.obolibrary.org/obo/GO_0010710 regulation of collagen catabolic process http://purl.obolibrary.org/obo/GO_0010712 regulation of collagen metabolic process Any process that modulates the rate, frequency or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix. http://purl.obolibrary.org/obo/GO_0010711 negative regulation of collagen catabolic process http://purl.obolibrary.org/obo/GO_0010713 negative regulation of collagen metabolic process Any process that decreases the rate, frequency or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix. http://purl.obolibrary.org/obo/UBERON_0002089 thoracodorsal vein http://purl.obolibrary.org/obo/UBERON_0001638 vein Companion vein of the thoracodorsal artery, draining the apical part of the latissimus dorsi and merging with the circumflex scapular vein to form a subscapular vein. http://purl.obolibrary.org/obo/GO_0010712 regulation of collagen metabolic process http://purl.obolibrary.org/obo/GO_0019222 regulation of metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. http://purl.obolibrary.org/obo/GO_0010713 negative regulation of collagen metabolic process http://purl.obolibrary.org/obo/GO_0010712 regulation of collagen metabolic process Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. http://purl.obolibrary.org/obo/UBERON_0002090 postcranial axial skeleton http://purl.obolibrary.org/obo/UBERON_0010912 subdivision of skeleton The postcranial subdivision of skeleton structural components forming the long axis of the vertebrate body; in Danio, consisting of the notochord, vertebrae, ribs, supraneurals, intermuscular bones, and unpaired median fins; in human consists of the bones of the vertebral column, the thoracic cage and the pelvis[ZFA+FMA]. http://purl.obolibrary.org/obo/GO_0010714 positive regulation of collagen metabolic process http://purl.obolibrary.org/obo/GO_0010712 regulation of collagen metabolic process Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. http://purl.obolibrary.org/obo/GO_0010715 regulation of extracellular matrix disassembly http://purl.obolibrary.org/obo/GO_1903053 regulation of extracellular matrix organization Any process that modulates the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix. http://purl.obolibrary.org/obo/UBERON_0002091 appendicular skeleton http://purl.obolibrary.org/obo/UBERON_0010912 subdivision of skeleton Subdivision of skeleton which which consists of all the skeletal elements in in the pectoral and pelvic appendage complexes[cjm]. http://purl.obolibrary.org/obo/GO_0010716 negative regulation of extracellular matrix disassembly http://purl.obolibrary.org/obo/GO_0010715 regulation of extracellular matrix disassembly Any process that decreases the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix. http://purl.obolibrary.org/obo/GO_0010717 regulation of epithelial to mesenchymal transition http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. http://purl.obolibrary.org/obo/UBERON_0002092 brain dura mater http://purl.obolibrary.org/obo/UBERON_0003547 brain meninx The fibrous membrane forming the outer of the three coverings that surrounds the brain within the cranial cavity; consists of two layers including the periosteal layer and the meningeal layer. http://purl.obolibrary.org/obo/GO_0010718 positive regulation of epithelial to mesenchymal transition http://purl.obolibrary.org/obo/GO_0045597 positive regulation of cell differentiation Any process that increases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition is where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. http://purl.obolibrary.org/obo/GO_0010719 negative regulation of epithelial to mesenchymal transition http://purl.obolibrary.org/obo/GO_0010717 regulation of epithelial to mesenchymal transition Any process that decreases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. http://purl.obolibrary.org/obo/UBERON_0002093 spinal dura mater http://purl.obolibrary.org/obo/UBERON_0002363 dura mater A dura mater that is part of a spinal cord [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0010720 positive regulation of cell development http://purl.obolibrary.org/obo/GO_0060284 regulation of cell development Any process that increases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. http://purl.obolibrary.org/obo/GO_0010721 negative regulation of cell development http://purl.obolibrary.org/obo/GO_0060284 regulation of cell development Any process that decreases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. http://purl.obolibrary.org/obo/UBERON_0002094 interventricular septum http://purl.obolibrary.org/obo/UBERON_0002099 cardiac septum Cardiac septum which separates the right ventricle from the left ventricle.[FMA]. http://purl.obolibrary.org/obo/GO_0010725 regulation of primitive erythrocyte differentiation http://purl.obolibrary.org/obo/GO_0045646 regulation of erythrocyte differentiation Any process that modulates the rate, frequency, or extent of primitive erythrocyte differentiation. Primitive erythrocyte differentiation occurs as part of the process of primitive hemopoiesis. http://purl.obolibrary.org/obo/GO_0010742 macrophage derived foam cell differentiation http://purl.obolibrary.org/obo/GO_0090077 foam cell differentiation The process in which a monocyte acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions. http://purl.obolibrary.org/obo/UBERON_0002095 mesentery http://purl.obolibrary.org/obo/UBERON_0000042 serous membrane Anatomical organ component composed of a double layer of serous membrane that suspends a viscus from the body wall or connects adjacent viscera and in doing so conveys blood vessels, lymphatics and nerves to and from the viscera. Examples: greater omentum, broad ligament of uterus, sigmoid mesocolon. http://purl.obolibrary.org/obo/GO_0010743 regulation of macrophage derived foam cell differentiation http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the rate, frequency or extent of macrophage derived foam cell differentiation. Macrophage derived foam cell differentiation is the process in which a macrophage acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions. http://purl.obolibrary.org/obo/GO_0010744 positive regulation of macrophage derived foam cell differentiation http://purl.obolibrary.org/obo/GO_0045597 positive regulation of cell differentiation Any process that increases the rate, frequency or extent of macrophage derived foam cell differentiation. Macrophage derived foam cell differentiation is the process in which a macrophage acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions. http://purl.obolibrary.org/obo/UBERON_0002097 skin of body http://purl.obolibrary.org/obo/UBERON_0010314 structure with developmental contribution from neural crest The organ covering the body that consists of the dermis and epidermis. http://purl.obolibrary.org/obo/GO_0010745 negative regulation of macrophage derived foam cell differentiation http://purl.obolibrary.org/obo/GO_0010743 regulation of macrophage derived foam cell differentiation Any process that decreases the rate, frequency or extent of macrophage derived foam cell differentiation. Macrophage derived foam cell differentiation is the process in which a macrophage acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions. http://purl.obolibrary.org/obo/GO_0010758 regulation of macrophage chemotaxis http://purl.obolibrary.org/obo/GO_1905521 regulation of macrophage migration Any process that modulates the rate, frequency or extent of macrophage chemotaxis. Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus. http://purl.obolibrary.org/obo/UBERON_0002099 cardiac septum http://purl.obolibrary.org/obo/UBERON_0003037 septum The thin membranous structure between parts of the heart, including the atria, ventricles, and outflow tract. http://purl.obolibrary.org/obo/GO_0010759 positive regulation of macrophage chemotaxis http://purl.obolibrary.org/obo/GO_1905523 positive regulation of macrophage migration Any process that increases the rate, frequency or extent of macrophage chemotaxis. Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus. http://purl.obolibrary.org/obo/GO_0010760 negative regulation of macrophage chemotaxis http://purl.obolibrary.org/obo/GO_1905522 negative regulation of macrophage migration Any process that decreases the rate, frequency or extent of macrophage chemotaxis. Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus. http://purl.obolibrary.org/obo/UBERON_0002100 trunk http://purl.obolibrary.org/obo/UBERON_0011676 subdivision of organism along main body axis Organism subdivision which is the part of the body posterior to the cervical region (or head, when cervical region not present) and anterior to the caudal region. Includes the sacrum when present. http://purl.obolibrary.org/obo/GO_0010761 fibroblast migration http://purl.obolibrary.org/obo/GO_0001667 ameboidal-type cell migration Cell migration that is accomplished by extension and retraction of a fibroblast pseudopodium. A fibroblast is a connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. http://purl.obolibrary.org/obo/UBERON_0002102 forelimb http://purl.obolibrary.org/obo/UBERON_0004710 pectoral appendage A (free) limb that is connected to a pectoral girdle. The extent of this structure includes autopod, stylopod and zeugopod regions when present, but excludes the pectoral girdle and its parts. http://purl.obolibrary.org/obo/GO_0010762 regulation of fibroblast migration http://purl.obolibrary.org/obo/GO_0030334 regulation of cell migration Any process that modulates the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium. http://purl.obolibrary.org/obo/GO_0010763 positive regulation of fibroblast migration http://purl.obolibrary.org/obo/GO_0010762 regulation of fibroblast migration Any process that increases the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium. http://purl.obolibrary.org/obo/UBERON_0002103 hindlimb http://purl.obolibrary.org/obo/UBERON_0004709 pelvic appendage A (free) limb that is connected to a pelvic girdle region. The extent of this structure includes autopod, stylopod and zeugopod regions when present, but excludes the pelvic girdle and its parts. http://purl.obolibrary.org/obo/GO_0010764 negative regulation of fibroblast migration http://purl.obolibrary.org/obo/GO_0010762 regulation of fibroblast migration Any process that decreases the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium. http://purl.obolibrary.org/obo/UBERON_0002104 visual system http://purl.obolibrary.org/obo/UBERON_0001032 sensory system The sensory system subserving the sense of vision. http://purl.obolibrary.org/obo/GO_0010765 positive regulation of sodium ion transport http://purl.obolibrary.org/obo/GO_0043270 positive regulation of monoatomic ion transport Any process that increases the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/UBERON_0002105 vestibulo-auditory system http://purl.obolibrary.org/obo/UBERON_0001032 sensory system Sensory system responsible for the perception of spatial orientation and auditory stimuli. http://purl.obolibrary.org/obo/GO_0010766 negative regulation of sodium ion transport http://purl.obolibrary.org/obo/GO_0043271 negative regulation of monoatomic ion transport Any process that decreases the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0010770 positive regulation of cell morphogenesis http://purl.obolibrary.org/obo/GO_0022604 regulation of cell morphogenesis Any process that increases the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. http://purl.obolibrary.org/obo/UBERON_0002109 pair of nares http://purl.obolibrary.org/obo/UBERON_0034925 anatomical collection Pair of nostrils. http://purl.obolibrary.org/obo/GO_0010771 negative regulation of cell morphogenesis http://purl.obolibrary.org/obo/GO_0022604 regulation of cell morphogenesis Any process that decreases the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. http://purl.obolibrary.org/obo/GO_0010816 calcitonin catabolic process http://purl.obolibrary.org/obo/GO_0042447 hormone catabolic process The chemical reactions and pathways resulting in the breakdown of the peptide calcitonin. http://purl.obolibrary.org/obo/UBERON_0002111 artery smooth muscle tissue http://purl.obolibrary.org/obo/UBERON_0004695 arterial system smooth muscle A portion of smooth muscle tissue that is part of an artery [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0010818 T cell chemotaxis http://purl.obolibrary.org/obo/GO_0072678 T cell migration The directed movement of a T cell in response to an external stimulus. A T cell is a type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex. http://purl.obolibrary.org/obo/UBERON_0002112 smooth muscle of esophagus http://purl.obolibrary.org/obo/UBERON_0001135 smooth muscle tissue A portion of smooth muscle tissue that is part of a esophagus [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0010819 regulation of T cell chemotaxis http://purl.obolibrary.org/obo/GO_2000404 regulation of T cell migration Any process that modulates the rate, frequency or extent of T cell chemotaxis. T cell chemotaxis is the directed movement of a T cell in response to an external stimulus. http://purl.obolibrary.org/obo/UBERON_0002118 right ovary http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure An ovary that is part of a right side of organism [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0010820 positive regulation of T cell chemotaxis http://purl.obolibrary.org/obo/GO_0140131 positive regulation of lymphocyte chemotaxis Any process that increases the rate, frequency or extent of T cell chemotaxis. T cell chemotaxis is the directed movement of a T cell in response to an external stimulus. http://purl.obolibrary.org/obo/GO_0010821 regulation of mitochondrion organization http://purl.obolibrary.org/obo/GO_0033043 regulation of organelle organization Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a mitochondrion. http://purl.obolibrary.org/obo/UBERON_0002119 left ovary http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure An ovary that is part of a left side of organism [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0010827 regulation of D-glucose transmembrane transport http://purl.obolibrary.org/obo/GO_0034762 regulation of transmembrane transport Any process that modulates the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0010828 positive regulation of D-glucose transmembrane transport http://purl.obolibrary.org/obo/GO_0010827 regulation of D-glucose transmembrane transport Any process that increases the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/UBERON_0002120 pronephros http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensible for larval life[GO]. http://purl.obolibrary.org/obo/GO_0010829 negative regulation of D-glucose transmembrane transport http://purl.obolibrary.org/obo/GO_0010827 regulation of D-glucose transmembrane transport Any process that decreases the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0010830 regulation of myotube differentiation http://purl.obolibrary.org/obo/GO_0051153 regulation of striated muscle cell differentiation Any process that modulates the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse. http://purl.obolibrary.org/obo/UBERON_0002122 capsule of thymus http://purl.obolibrary.org/obo/UBERON_0003893 capsule The fibrous connective tissue surrounding the thymus. http://purl.obolibrary.org/obo/GO_0010831 positive regulation of myotube differentiation http://purl.obolibrary.org/obo/GO_0051155 positive regulation of striated muscle cell differentiation Any process that activates, maintains or increases the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse. http://purl.obolibrary.org/obo/UBERON_0002123 cortex of thymus http://purl.obolibrary.org/obo/UBERON_0001851 cortex The outer part of a thymus lobule that surrounds the medulla and is composed of closely packed lymphocytes. http://purl.obolibrary.org/obo/GO_0010832 negative regulation of myotube differentiation http://purl.obolibrary.org/obo/GO_0051154 negative regulation of striated muscle cell differentiation Any process that decreases the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse. http://purl.obolibrary.org/obo/GO_0010837 regulation of keratinocyte proliferation http://purl.obolibrary.org/obo/GO_0050678 regulation of epithelial cell proliferation Any process that modulates the rate, frequency or extent of keratinocyte proliferation. Keratinocyte proliferation is the multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population. http://purl.obolibrary.org/obo/UBERON_0002124 medulla of thymus http://purl.obolibrary.org/obo/UBERON_0000958 medulla of organ Medullary portion of thymus. The reticulum is coarser than in the cortex, the lymphoid cells are relatively fewer in number, and there are found peculiar nest-like bodies, the concentric corpuscles of Hassall. These concentric corpuscles are composed of a central mass, consisting of one or more granular cells, and of a capsule formed of epithelioid cells. They are the remains of the epithelial tubes, which grow out from the third branchial pouches of the embryo to form the thymus. Each follicle is surrounded by a vascular plexus, from which vessels pass into the interior, and radiate from the periphery toward the center, forming a second zone just within the margin of the medullary portion. In the center of the medullary portion there are very few vessels, and they are of minute size. http://purl.obolibrary.org/obo/GO_0010838 positive regulation of keratinocyte proliferation http://purl.obolibrary.org/obo/GO_0010837 regulation of keratinocyte proliferation Any process that increases the rate, frequency or extent of keratinocyte proliferation. Keratinocyte proliferation is the multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population. http://purl.obolibrary.org/obo/GO_0010839 negative regulation of keratinocyte proliferation http://purl.obolibrary.org/obo/GO_0010837 regulation of keratinocyte proliferation Any process that decreases the rate, frequency or extent of keratinocyte proliferation. Keratinocyte proliferation is the multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population. http://purl.obolibrary.org/obo/UBERON_0002125 thymus lobule http://purl.obolibrary.org/obo/UBERON_0009911 lobule A lobule that is part of a thymus. Divided into an outer cortex and inner medulla and separated from each other by connective tissue septa, but with the medullary tissue continuous from lobule to lobule.[ncit,modified]. http://purl.obolibrary.org/obo/GO_0010842 retina layer formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process in which the vertebrate retina is organized into three laminae: the outer nuclear layer (ONL), which contains photoreceptor nuclei; the inner nuclear layer (INL), which contains amacrine, bipolar and horizontal cells; and the retinal ganglion cell (RGC) layer. Between the inner and outer nuclear layers, the outer plexiform layer (OPL) contains connections between the photoreceptors and bipolar and horizontal cells. The inner plexiform layer (IPL) is positioned between the INL and the ganglion cell layer and contains the dendrites of RGCs and processes of bipolar and amacrine cells. Spanning all layers of the retina are the radially oriented Mueller glia. http://purl.obolibrary.org/obo/GO_0010882 regulation of cardiac muscle contraction by calcium ion signaling http://purl.obolibrary.org/obo/GO_0055117 regulation of cardiac muscle contraction Any process that modulates the frequency, rate or extent of cardiac muscle contraction by changing the calcium ion signals that trigger contraction. http://purl.obolibrary.org/obo/UBERON_0002128 superior olivary complex http://purl.obolibrary.org/obo/UBERON_0019263 gray matter of hindbrain A collection of brainstem nuclei that functions in multiple aspects of hearing and is an important component of the ascending and descending auditory pathways of the auditory system. http://purl.obolibrary.org/obo/GO_0010892 positive regulation of mitochondrial translation in response to stress http://purl.obolibrary.org/obo/GO_0070131 positive regulation of mitochondrial translation Any process that activates or increases the frequency, rate or extent of mitochondrial translation as a result of a stimulus indicating the organism is under stress. http://purl.obolibrary.org/obo/GO_0010893 positive regulation of steroid biosynthetic process http://purl.obolibrary.org/obo/GO_0050810 regulation of steroid biosynthetic process Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus. http://purl.obolibrary.org/obo/UBERON_0002129 cerebellar cortex http://purl.obolibrary.org/obo/UBERON_0019263 gray matter of hindbrain The superficial gray matter of the cerebellum. It consists of three main layers, the molecular layer, the Purkinje cell layer and the granule cell layer. http://purl.obolibrary.org/obo/GO_0010894 negative regulation of steroid biosynthetic process http://purl.obolibrary.org/obo/GO_0051055 negative regulation of lipid biosynthetic process Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus. http://purl.obolibrary.org/obo/GO_0010907 positive regulation of glucose metabolic process http://purl.obolibrary.org/obo/GO_0045913 positive regulation of carbohydrate metabolic process Any process that increases the rate, frequency or extent of glucose metabolism. Glucose metabolic processes are the chemical reactions and pathways involving glucose, the aldohexose gluco-hexose. http://purl.obolibrary.org/obo/UBERON_0002130 cerebellar nuclear complex http://purl.obolibrary.org/obo/UBERON_0019263 gray matter of hindbrain The gray matter nuclei located in the center of the cerebellum, embedded in the white matter, which receive inhibitory (GABAergic) inputs from Purkinje cells in the cerebellar cortex and excitatory (glutamatergic) inputs from mossy fiber pathways; all output fibers of the cerebellum originate from the these nuclei[MP]. http://purl.obolibrary.org/obo/GO_0010931 macrophage tolerance induction http://purl.obolibrary.org/obo/GO_0002507 tolerance induction A process involving any mechanism for tolerance induction in macrophages. http://purl.obolibrary.org/obo/GO_0010932 regulation of macrophage tolerance induction http://purl.obolibrary.org/obo/GO_0002643 regulation of tolerance induction Any process that modulates the frequency, rate, or extent of macrophage tolerance induction. http://purl.obolibrary.org/obo/UBERON_0002139 subcommissural organ http://purl.obolibrary.org/obo/UBERON_0010134 secretory circumventricular organ The subcommissural organ is a circumventricular organ consisting of ependymal and hypendymal cells which secrete SCO-spondin[WP,partially vetted]. http://purl.obolibrary.org/obo/GO_0010933 positive regulation of macrophage tolerance induction http://purl.obolibrary.org/obo/GO_0010932 regulation of macrophage tolerance induction Any process that increases the frequency, rate, or extent of B cell tolerance induction. http://purl.obolibrary.org/obo/GO_0010934 macrophage cytokine production http://purl.obolibrary.org/obo/GO_0061082 myeloid leukocyte cytokine production The appearance of a macrophage cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. http://purl.obolibrary.org/obo/UBERON_0002142 pedunculopontine tegmental nucleus http://purl.obolibrary.org/obo/UBERON_0007415 nucleus of midbrain reticular formation The pedunculopontine nucleus (PPN) (or pedunculopontine tegmental nucleus, PPTN) is located in the brainstem, caudal to the substantia nigra and adjacent to the superior cerebellar peduncle. It is composed by a wide variety of neurochemical cell types, including cholinergic, glutamatergic and GABAergic cells. In the classical sense, the PPN is considered to be one of the main components of the reticular activating system. [WP,unvetted]. http://purl.obolibrary.org/obo/GO_0010935 regulation of macrophage cytokine production http://purl.obolibrary.org/obo/GO_0002718 regulation of cytokine production involved in immune response Any process that modulates the rate, frequency or extent of macrophage cytokine production. Macrophage cytokine production is the appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. http://purl.obolibrary.org/obo/GO_0010936 negative regulation of macrophage cytokine production http://purl.obolibrary.org/obo/GO_0010935 regulation of macrophage cytokine production Any process that decreases the rate, frequency or extent of macrophage cytokine production. Macrophage cytokine production is the appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. http://purl.obolibrary.org/obo/UBERON_0002148 locus ceruleus http://purl.obolibrary.org/obo/UBERON_0009662 hindbrain nucleus The locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic[GO]. Bluish region in the superior angle of the fourth ventricle floor, corresponding to melanin-like pigmented nerve cells which lie lateral to the ponto-mesencephalic central gray (griseum centrale). It is also known as nucleus pigmentosus pontis[GAID]. http://purl.obolibrary.org/obo/GO_0010937 regulation of cytoplasmic microtubule depolymerization http://purl.obolibrary.org/obo/GO_0031114 regulation of microtubule depolymerization Any process that modulates the frequency, rate or extent of cytoplasmic microtubule depolymerization. http://purl.obolibrary.org/obo/GO_0010938 cytoplasmic microtubule depolymerization http://purl.obolibrary.org/obo/GO_0031122 cytoplasmic microtubule organization The removal of tubulin heterodimers from one or both ends of a cytoplasmic microtubule. http://purl.obolibrary.org/obo/UBERON_0002149 superior salivatory nucleus http://purl.obolibrary.org/obo/UBERON_0007635 nucleus of medulla oblongata Nucleus containing parasympathetic neurons giving rise to the parasympathetic division of the facial nerve, innervating the salivary glands (Brodal, Neurological Anatomy, 3rd ed., 1981, pg 703). http://purl.obolibrary.org/obo/GO_0010948 negative regulation of cell cycle process http://purl.obolibrary.org/obo/GO_0045786 negative regulation of cell cycle Any process that decreases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. http://purl.obolibrary.org/obo/GO_0010955 negative regulation of protein processing http://purl.obolibrary.org/obo/GO_1903318 negative regulation of protein maturation Any process that decreases the rate, frequency or extent of protein maturation by peptide bond cleavage. http://purl.obolibrary.org/obo/UBERON_0002151 pontine nuclear group http://purl.obolibrary.org/obo/UBERON_0009662 hindbrain nucleus Nuclei in the basal pons, intermingled among the descending axons from the cortex, that receive neocrotcial input and give rise to many axons that cross the midline to enter the contralateral cerebellum (Butler and Hodos, Comparative Vertebrate Neuroanatomy, 2nd ed., 2005, pg 135). http://purl.obolibrary.org/obo/GO_0010958 regulation of amino acid import across plasma membrane http://purl.obolibrary.org/obo/GO_1903789 regulation of amino acid transmembrane transport Any process that modulates the frequency, rate or extent of amino acid import into a cell. http://purl.obolibrary.org/obo/UBERON_0002152 middle cerebellar peduncle http://purl.obolibrary.org/obo/UBERON_0019292 white matter of pons Regional part of medullary white matter (according to Neuronames) primarily found at the level of the pons, consisting of a very large bundle of fibers originating in the pontine nuclei projecting to the cerebellum (MM). http://purl.obolibrary.org/obo/GO_0010966 regulation of phosphate transport http://purl.obolibrary.org/obo/GO_0051049 regulation of transport Any process that modulates the frequency, rate or extent of phosphate transport. Phosphate transport is the directed movement of phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/UBERON_0002162 area postrema http://purl.obolibrary.org/obo/UBERON_0010135 sensory circumventricular organ A small, rounded eminence on each side of the fourth ventricle, which receives nerve fibers from the solitary nucleus , spinal cord, and adjacent areas of the medulla. The area postrema lies outside the blood-brain barrier and its functions include acting as an emetic chemoreceptor. http://purl.obolibrary.org/obo/GO_0010968 regulation of microtubule nucleation http://purl.obolibrary.org/obo/GO_0031113 regulation of microtubule polymerization Any process that modulates the rate, frequency or extent of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell. http://purl.obolibrary.org/obo/UBERON_0002166 endocardium of atrium http://purl.obolibrary.org/obo/UBERON_0002165 endocardium Endocardium that is part of the atrium. http://purl.obolibrary.org/obo/GO_0010975 regulation of neuron projection development http://purl.obolibrary.org/obo/GO_0120035 regulation of plasma membrane bounded cell projection organization Any process that modulates the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites). http://purl.obolibrary.org/obo/UBERON_0002167 right lung http://purl.obolibrary.org/obo/UBERON_0002048 lung Lung which consists of the right upper lobe, middle lobe and right lower lobe.[FMA]. http://purl.obolibrary.org/obo/GO_0010976 positive regulation of neuron projection development http://purl.obolibrary.org/obo/GO_0031346 positive regulation of cell projection organization Any process that increases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites). http://purl.obolibrary.org/obo/UBERON_0002168 left lung http://purl.obolibrary.org/obo/UBERON_0002048 lung Lung which consists of the left upper lobe and left lower lobe.[FMA]. http://purl.obolibrary.org/obo/UBERON_0002169 alveolar sac http://purl.obolibrary.org/obo/UBERON_0007499 epithelial sac The small terminal dilation of the alveolar ducts around which the alveoli form pocket-like clusters. http://purl.obolibrary.org/obo/GO_0010977 negative regulation of neuron projection development http://purl.obolibrary.org/obo/GO_0010975 regulation of neuron projection development Any process that decreases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites). http://purl.obolibrary.org/obo/UBERON_0002173 pulmonary alveolar duct http://purl.obolibrary.org/obo/UBERON_0000117 respiratory tube The respiratory conducting tubes distal to the respiratory bronchiole that lead to the alveolar sacs and the alveoli. http://purl.obolibrary.org/obo/UBERON_0002180 ventral funiculus of spinal cord http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure The white substance of the spinal cord lying on either side between the ventral median fissure and the ventral roots of the spinal nerves. http://purl.obolibrary.org/obo/GO_0012506 vesicle membrane http://purl.obolibrary.org/obo/GO_0031090 organelle membrane The lipid bilayer surrounding any membrane-bounded vesicle in the cell. http://purl.obolibrary.org/obo/UBERON_0002183 lobar bronchus http://purl.obolibrary.org/obo/UBERON_0035767 intrapulmonary bronchus The lobar bronchus is the major airway within the respiratory tree that starts by division of the principal bronchi on both sides and ends at the point of its own subdivision into tertiary or segmental bronchi[GO]. http://purl.obolibrary.org/obo/GO_0014002 astrocyte development http://purl.obolibrary.org/obo/GO_0021782 glial cell development The process aimed at the progression of an astrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function. http://purl.obolibrary.org/obo/UBERON_0002184 segmental bronchus http://purl.obolibrary.org/obo/UBERON_0035767 intrapulmonary bronchus The tertiary bronchi (also known as the segmental bronchi) arise from the secondary bronchi. The respiratory epithelium lining their lumen is surrounded by a layer of smooth muscle. This layer is composed of two ribbons of smooth muscle that spiral in opposite directions. The smooth muscle layer is surrounded by irregular plates of hyaline cartilage which help maintain the patency of the airway. Each of the tertiary bronchi serves a specific bronchopulmonary segment. There are 10 tertiary bronchi in the right lung, and eight in the left. The tertiary bronchi get smaller and divide into primary bronchioles. [WP,unvetted]. http://purl.obolibrary.org/obo/GO_0014003 oligodendrocyte development http://purl.obolibrary.org/obo/GO_0021782 glial cell development The process aimed at the progression of an oligodendrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. An oligodendrocyte is a type of glial cell involved in myelinating the axons in the central nervous system. http://purl.obolibrary.org/obo/GO_0014004 microglia differentiation http://purl.obolibrary.org/obo/GO_0030225 macrophage differentiation The process in which a relatively unspecialized cell acquires specialized features of a microglial cell. Microglia are glial cells that act as the immune cells of the central nervous system. They form part of the supporting structure of this system. http://purl.obolibrary.org/obo/UBERON_0002186 bronchiole http://purl.obolibrary.org/obo/UBERON_0000117 respiratory tube The conducting airway of the lungs found terminal to the bronchi; these structures contain neither cartilage nor mucous-secreting glands; the epithelium of the bronchioles becomes thinner with each branching. http://purl.obolibrary.org/obo/GO_0014005 microglia development http://purl.obolibrary.org/obo/GO_0061515 myeloid cell development The process aimed at the progression of a microglial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. http://purl.obolibrary.org/obo/UBERON_0002187 terminal bronchiole http://purl.obolibrary.org/obo/UBERON_0002186 bronchiole A bronchiole that is part of a secondary pulmonary lobule and the last conducting structure of a non-respiratory bronchiole; after this point, the airways have alveoli in their walls. http://purl.obolibrary.org/obo/GO_0014006 regulation of microglia differentiation http://purl.obolibrary.org/obo/GO_0045685 regulation of glial cell differentiation Any process that modulates the frequency, rate or extent of microglia differentiation, the process in which a relatively unspecialized cell acquires specialized features of a microglial cell. http://purl.obolibrary.org/obo/UBERON_0002188 respiratory bronchiole http://purl.obolibrary.org/obo/UBERON_0002186 bronchiole A bronchiole that is the first segment of the respiratory zone. http://purl.obolibrary.org/obo/UBERON_0002190 subcutaneous adipose tissue http://purl.obolibrary.org/obo/UBERON_0001013 adipose tissue A portion of adipose tissue that is part of the hypodermis, beneath the dermis. http://purl.obolibrary.org/obo/GO_0014007 negative regulation of microglia differentiation http://purl.obolibrary.org/obo/GO_0045686 negative regulation of glial cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of microglia differentiation, the process in which a relatively unspecialized cell acquires specialized features of a microglial cell. http://purl.obolibrary.org/obo/UBERON_0002191 subiculum http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain Part of the hippocampal formation that is bounded by the entorhinal cortex and area CA1. It is characterized on the CA1 border by an abrupt widening of the pyramidal cell layer. A molecular layer is present that is continuous with that of CA1, although the stratum radiatum is no longer present. The stratum oriens is also not present. adapted from Paxinos, G. The rat central nervous system, 2nd ed, Academic Press, San Diego, 1995, pg. 468). http://purl.obolibrary.org/obo/GO_0014008 positive regulation of microglia differentiation http://purl.obolibrary.org/obo/GO_0045687 positive regulation of glial cell differentiation Any process that activates, maintains or increases the frequency, rate or extent of microglia differentiation, the process in which a relatively unspecialized cell acquires specialized features of a microglial cell. http://purl.obolibrary.org/obo/GO_0014009 glial cell proliferation http://purl.obolibrary.org/obo/GO_0008283 cell population proliferation The multiplication or reproduction of glial cells by cell division, resulting in the expansion of their population. Glial cells exist throughout the nervous system, and include Schwann cells, astrocytes, and oligodendrocytes among others. http://purl.obolibrary.org/obo/UBERON_0002193 hemolymphoid system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system Anatomical cluster consisting of the hematopoietic system and the lymphoid system, or its analogs. http://purl.obolibrary.org/obo/UBERON_0002194 capsule of lymph node http://purl.obolibrary.org/obo/UBERON_0003893 capsule Capsule surrounding lymph node composed of connective tissue with some plain muscle fibers. http://purl.obolibrary.org/obo/GO_0014010 Schwann cell proliferation http://purl.obolibrary.org/obo/GO_0014009 glial cell proliferation The multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system. http://purl.obolibrary.org/obo/UBERON_0002195 trabecula of lymph node http://purl.obolibrary.org/obo/UBERON_0000440 trabecula Membranous process coming from capsule of lymph node[WP]. http://purl.obolibrary.org/obo/GO_0014013 regulation of gliogenesis http://purl.obolibrary.org/obo/GO_0050767 regulation of neurogenesis Any process that modulates the frequency, rate or extent of gliogenesis, the formation of mature glia. http://purl.obolibrary.org/obo/UBERON_0002196 adenohypophysis http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure The glandular, anterior lobe of the pituitary gland. The anterior pituitary regulates several physiological processes including stress, growth, and reproduction[WP]. The anterior lobe of the hypophysis (pituitary gland). This lobe contains cells that produce prolactin, growth hormone, thyroid-stimulating hormone, follicle-stimulating hormone and proopiomelanocortin[ZFA]. http://purl.obolibrary.org/obo/GO_0014014 negative regulation of gliogenesis http://purl.obolibrary.org/obo/GO_0014013 regulation of gliogenesis Any process that stops, prevents, or reduces the frequency, rate or extent of gliogenesis, the formation of mature glia. http://purl.obolibrary.org/obo/GO_0014015 positive regulation of gliogenesis http://purl.obolibrary.org/obo/GO_0014013 regulation of gliogenesis Any process that activates or increases the frequency, rate or extent of gliogenesis, the formation of mature glia. http://purl.obolibrary.org/obo/GO_0014016 neuroblast differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a neuroblast. There are at least four stages through which the pluripotent cells of epiblast or blastula become neuroblasts. http://purl.obolibrary.org/obo/GO_0014019 neuroblast development http://purl.obolibrary.org/obo/GO_0048468 cell development The process aimed at the progression of a neuroblast over time, from initial commitment of the cell to a specific state, to the mature neuroblast. It does not include processes where the neuroblast turns into a glial cell or a neuron. http://purl.obolibrary.org/obo/GO_0014023 neural rod formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The formation of a solid rod of neurectoderm derived from the neural keel. The neural rod is roughly circular in cross section. Neural rod formation occurs during primary neurulation in teleosts. http://purl.obolibrary.org/obo/GO_0014025 neural keel formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The formation of a thickened region of the neurectoderm that is roughly triangular in cross section. The neural keel develops from the neural plate and develops into the neural rod. Neural keel formation occurs during primary neurulation in teleosts. http://purl.obolibrary.org/obo/GO_0014028 notochord formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The formation of the notochord from the chordamesoderm. The notochord is composed of large cells packed within a firm connective tissue sheath and is found in all chordates at the ventral surface of the neural tube. In vertebrates, the notochord contributes to the vertebral column. http://purl.obolibrary.org/obo/GO_0014029 neural crest formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation proceeds. http://purl.obolibrary.org/obo/GO_0014031 mesenchymal cell development http://purl.obolibrary.org/obo/GO_0048468 cell development The process aimed at the progression of a mesenchymal cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell. http://purl.obolibrary.org/obo/GO_0014033 neural crest cell differentiation http://purl.obolibrary.org/obo/GO_0048863 stem cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a neural crest cell. http://purl.obolibrary.org/obo/UBERON_0002197 median eminence of neurohypophysis http://purl.obolibrary.org/obo/UBERON_0010134 secretory circumventricular organ Elevation on the ventral surface of the brain located at the zone of attachment between the hypothalamic floor and the hypophysis (Butler and Hodos, Comparative Vertebrate Neuroanatomy, 2nd ed., 2005, pg. 446). http://purl.obolibrary.org/obo/GO_0014037 Schwann cell differentiation http://purl.obolibrary.org/obo/GO_0010001 glial cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a Schwann cell. Schwann cells are found in the peripheral nervous system, where they insulate neurons and axons, and regulate the environment in which neurons function. http://purl.obolibrary.org/obo/UBERON_0002199 integument http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision The dermis, epidermis and hypodermis. http://purl.obolibrary.org/obo/GO_0014038 regulation of Schwann cell differentiation http://purl.obolibrary.org/obo/GO_0045685 regulation of glial cell differentiation Any process that modulates the frequency, rate or extent of Schwann cell differentiation. http://purl.obolibrary.org/obo/UBERON_0002200 vasculature of head http://purl.obolibrary.org/obo/UBERON_0002049 vasculature Vasculature that is part of a head [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0014039 negative regulation of Schwann cell differentiation http://purl.obolibrary.org/obo/GO_0045686 negative regulation of glial cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of Schwann cell differentiation. http://purl.obolibrary.org/obo/UBERON_0002201 vasculature of trunk http://purl.obolibrary.org/obo/UBERON_0002049 vasculature A vasculature that is part of a trunk [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0014040 positive regulation of Schwann cell differentiation http://purl.obolibrary.org/obo/GO_0045687 positive regulation of glial cell differentiation Any process that activates or increases the frequency, rate or extent of Schwann cell differentiation. http://purl.obolibrary.org/obo/UBERON_0002202 submucosa of trachea http://purl.obolibrary.org/obo/UBERON_0004777 respiratory system submucosa A submucosa that is part of a trachea. http://purl.obolibrary.org/obo/GO_0014041 regulation of neuron maturation http://purl.obolibrary.org/obo/GO_0045664 regulation of neuron differentiation Any process that modulates the frequency, rate or extent of neuron maturation, the process leading to the attainment of the full functional capacity of a neuron. This process is independent of morphogenetic change. http://purl.obolibrary.org/obo/UBERON_0002203 vasculature of eye http://purl.obolibrary.org/obo/UBERON_0006876 vasculature of organ Vasculature that is part of the eye region. http://purl.obolibrary.org/obo/GO_0014042 positive regulation of neuron maturation http://purl.obolibrary.org/obo/GO_1903431 positive regulation of cell maturation Any process that activates or increases the frequency, rate or extent of neuron maturation. http://purl.obolibrary.org/obo/UBERON_0002206 mammillary body http://purl.obolibrary.org/obo/UBERON_0000064 organ part One of two hemispherical bulges on the base of the posterior hypothalamus (Butler and Hodos, Comparative Vertebrate Neuroanatomy, 2nd ed., 2005, pg 455). http://purl.obolibrary.org/obo/GO_0014043 negative regulation of neuron maturation http://purl.obolibrary.org/obo/GO_1903430 negative regulation of cell maturation Any process that stops, prevents, or reduces the frequency, rate or extent of neuron maturation. http://purl.obolibrary.org/obo/UBERON_0002209 fibrous joint http://purl.obolibrary.org/obo/UBERON_0011134 nonsynovial joint Nonsynovial joint in which the articulating bones or cartilages are connected by ligaments. Examples: sagittal suture, inferior tibiofibular syndesmosis, gomphosis.[FMA]. http://purl.obolibrary.org/obo/GO_0014044 Schwann cell development http://purl.obolibrary.org/obo/GO_0021782 glial cell development The process aimed at the progression of a Schwann cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. Schwann cells are found in the peripheral nervous system, where they insulate neurons and axons, and regulate the environment in which neurons function. http://purl.obolibrary.org/obo/UBERON_0002210 syndesmosis http://purl.obolibrary.org/obo/UBERON_0002213 cartilaginous joint Fibrous joint in which the articulating bones or cartilages of the vertebral column and the limbs as well as articulating ossicles, are connected by skeletal ligaments or membranes. Examples: Intervertebral syndesmosis, inferior tibiofibular joint.[FMA]. http://purl.obolibrary.org/obo/GO_0014046 dopamine secretion http://purl.obolibrary.org/obo/GO_0050432 catecholamine secretion The regulated release of dopamine by a cell. Dopamine is a catecholamine and a precursor of adrenaline and noradrenaline. It acts as a neurotransmitter in the central nervous system but it is also produced peripherally and acts as a hormone. http://purl.obolibrary.org/obo/UBERON_0002211 nerve root http://purl.obolibrary.org/obo/UBERON_0000122 neuron projection bundle A continuation of the neuron projection bundle component of a nerve inside, crossing or immediately outside the central nervous system. http://purl.obolibrary.org/obo/GO_0014047 glutamate secretion http://purl.obolibrary.org/obo/GO_0015800 acidic amino acid transport The controlled release of glutamate by a cell. The glutamate is the most abundant excitatory neurotransmitter in the nervous system. http://purl.obolibrary.org/obo/UBERON_0002212 macula of saccule of membranous labyrinth http://purl.obolibrary.org/obo/UBERON_0000054 macula The oval neuroepithelial sensory receptor in the anterior wall of the saccule; hair cells of the neuroepithelium support the statoconial membrane and have terminal arborizations of vestibular nerve fibers around their bodies. http://purl.obolibrary.org/obo/GO_0014048 regulation of glutamate secretion http://purl.obolibrary.org/obo/GO_0032890 regulation of organic acid transport Any process that modulates the frequency, rate or extent of the controlled release of glutamate. http://purl.obolibrary.org/obo/UBERON_0002213 cartilaginous joint http://purl.obolibrary.org/obo/UBERON_0011134 nonsynovial joint Nonsynovial joint in which the articulating bones or cartilages are connected by cartilage. Examples: Spheno-occipital synchondrosis, first sternocostal joint, pubic symphysis.[FMA]. http://purl.obolibrary.org/obo/GO_0014049 positive regulation of glutamate secretion http://purl.obolibrary.org/obo/GO_0014048 regulation of glutamate secretion Any process that activates or increases the frequency, rate or extent of the controlled release of glutamate. http://purl.obolibrary.org/obo/UBERON_0002214 macula of utricle of membranous labyrinth http://purl.obolibrary.org/obo/UBERON_0000054 macula The neuroepithelial sensory receptor in the inferolateral wall of the utricle; hair cells of the neuroepithelium support the statoconial membrane and have terminal arborizations of vestibular nerve fibers around their bodies; normally sensitive to linear acceleration in the longitudinal axis of the body and to gravitational influences. http://purl.obolibrary.org/obo/GO_0014050 negative regulation of glutamate secretion http://purl.obolibrary.org/obo/GO_0014048 regulation of glutamate secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of glutamate. http://purl.obolibrary.org/obo/UBERON_0002215 synchondrosis http://purl.obolibrary.org/obo/UBERON_0002213 cartilaginous joint Cartilaginous joint in which the articulating bones or cartilages are connected by hyaline cartilage. Examples: spheno-occipital synchondrosis, first sternocostal joint.[FMA]. http://purl.obolibrary.org/obo/GO_0014051 gamma-aminobutyric acid secretion http://purl.obolibrary.org/obo/GO_0015812 gamma-aminobutyric acid transport The regulated release of gamma-aminobutyric acid by a cell or a tissue. The gamma-aminobutyric acid is the principal inhibitory neurotransmitter in the brain but is also found in several extraneural tissues. http://purl.obolibrary.org/obo/UBERON_0002216 symphysis http://purl.obolibrary.org/obo/UBERON_0002213 cartilaginous joint Cartilaginous joint in which the articulating bones or cartilages are connected by fibrocartilage. Examples: pubic symphysis, intervertebral symphysis, manubriosternal joint.[FMA]. http://purl.obolibrary.org/obo/GO_0014052 regulation of gamma-aminobutyric acid secretion http://purl.obolibrary.org/obo/GO_0032890 regulation of organic acid transport Any process that modulates the frequency, rate or extent of the regulated release of gamma-aminobutyric acid. http://purl.obolibrary.org/obo/UBERON_0002217 synovial joint http://purl.obolibrary.org/obo/UBERON_0000982 skeletal joint Joint in which the articulating bones or cartilages are connected by an articular capsule which encloses a synovial membrane and a synovial cavity. Examples: Temporomandibular joint, knee joint.[FMA]. http://purl.obolibrary.org/obo/GO_0014053 negative regulation of gamma-aminobutyric acid secretion http://purl.obolibrary.org/obo/GO_0014052 regulation of gamma-aminobutyric acid secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of gamma-aminobutyric acid. http://purl.obolibrary.org/obo/UBERON_0002219 subfornical organ http://purl.obolibrary.org/obo/UBERON_0010135 sensory circumventricular organ Group of neurons situated on the ventral surface of the fornix at the level of the foramen of Monro in the third ventricle (adapted from Wikipedia via NIF). http://purl.obolibrary.org/obo/GO_0014054 positive regulation of gamma-aminobutyric acid secretion http://purl.obolibrary.org/obo/GO_0014052 regulation of gamma-aminobutyric acid secretion Any process that activates or increases the frequency, rate or extent of the regulated release of gamma-aminobutyric acid. http://purl.obolibrary.org/obo/UBERON_0002222 perichondrium http://purl.obolibrary.org/obo/UBERON_0002384 connective tissue Fibrous connective tissue that surrounds cartilage. http://purl.obolibrary.org/obo/GO_0014055 acetylcholine secretion, neurotransmission http://purl.obolibrary.org/obo/GO_0061526 acetylcholine secretion The regulated release of acetylcholine by a cell. The acetylcholine acts as a neurotransmitter that acts in both the peripheral nervous system (PNS) and central nervous system (CNS). http://purl.obolibrary.org/obo/UBERON_0002224 thoracic cavity http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space The part of the coelemic cavity lumen that is enclosed by the walls of the thorax. http://purl.obolibrary.org/obo/GO_0014056 regulation of acetylcholine secretion, neurotransmission http://purl.obolibrary.org/obo/GO_0051952 regulation of amine transport Any process that modulates the frequency, rate or extent of the regulated release of acetylcholine. http://purl.obolibrary.org/obo/UBERON_0002227 spiral organ of cochlea http://purl.obolibrary.org/obo/UBERON_0000020 sense organ The organ of Corti (or spiral organ) is the organ in the inner ear of mammals that contains auditory sensory cells, or 'hair cells.' [WP,unvetted]. http://purl.obolibrary.org/obo/GO_0014057 positive regulation of acetylcholine secretion, neurotransmission http://purl.obolibrary.org/obo/GO_0051954 positive regulation of amine transport Any process that activates or increases the frequency, rate or extent of the regulated release of acetylcholine. http://purl.obolibrary.org/obo/UBERON_0002228 rib http://purl.obolibrary.org/obo/UBERON_0015019 rib endochondral element An intersegmental rod-shaped bone that forms in the peritoneal membrane and attach to the vertebral parapophyses. http://purl.obolibrary.org/obo/GO_0014058 negative regulation of acetylcholine secretion, neurotransmission http://purl.obolibrary.org/obo/GO_0051953 negative regulation of amine transport Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of acetylcholine. http://purl.obolibrary.org/obo/UBERON_0002234 proximal phalanx of manus http://purl.obolibrary.org/obo/UBERON_0004302 proximal phalanx A proximal phalanx that is part of a finger [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0014059 regulation of dopamine secretion http://purl.obolibrary.org/obo/GO_0050433 regulation of catecholamine secretion Any process that modulates the frequency, rate or extent of the regulated release of dopamine. http://purl.obolibrary.org/obo/UBERON_0002237 true rib http://purl.obolibrary.org/obo/UBERON_0002228 rib A rib that is ventrally connected to the sternum. http://purl.obolibrary.org/obo/GO_0014060 regulation of epinephrine secretion http://purl.obolibrary.org/obo/GO_0050433 regulation of catecholamine secretion Any process that modulates the frequency, rate or extent of the regulated release of epinephrine. http://purl.obolibrary.org/obo/UBERON_0002241 chondrocranium http://purl.obolibrary.org/obo/UBERON_0011159 primary subdivision of cranial skeletal system Endoskeletal elements that encase the brain, nose, inner ear[cjm]. that part of the neurocranium formed by endochondral ossification and comprising the bones of the base of the skull[TFD]. http://purl.obolibrary.org/obo/GO_0014061 regulation of norepinephrine secretion http://purl.obolibrary.org/obo/GO_0050433 regulation of catecholamine secretion Any process that modulates the frequency, rate or extent of the regulated release of norepinephrine. http://purl.obolibrary.org/obo/UBERON_0002242 nucleus pulposus http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure The jelly-like substance in the middle of the spinal disc which is a remnant of the notochord. http://purl.obolibrary.org/obo/GO_0014062 regulation of serotonin secretion http://purl.obolibrary.org/obo/GO_0043269 regulation of monoatomic ion transport Any process that modulates the frequency, rate or extent of the regulated release of serotonin. http://purl.obolibrary.org/obo/UBERON_0002245 cerebellar hemisphere http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure A paired regions of the cerebellum that lie outside and lateral to the central vermis[MP]. The cerebellum consists of three parts, a median and two lateral, which are continuous with each other, and are substantially the same in structure. The median portion is constricted, and is called the vermis, from its annulated appearance which it owes to the transverse ridges and furrows upon it; the lateral expanded portions are named the hemispheres. The lateral hemisphere is considered the portion of the cerebellum to develop most recently. [WP,unvetted]. http://purl.obolibrary.org/obo/GO_0014063 negative regulation of serotonin secretion http://purl.obolibrary.org/obo/GO_0043271 negative regulation of monoatomic ion transport Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of serotonin. http://purl.obolibrary.org/obo/UBERON_0002255 vomeronasal organ http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure An organ thought to supplement the olfactory system in receiving pheromonic communication. The sensory part of the organ is in two long, thin sacs, situated on either side of the nasal septum at its base. http://purl.obolibrary.org/obo/GO_0014064 positive regulation of serotonin secretion http://purl.obolibrary.org/obo/GO_0043270 positive regulation of monoatomic ion transport Any process that activates or increases the frequency, rate or extent of the regulated release of serotonin. http://purl.obolibrary.org/obo/UBERON_0002256 dorsal horn of spinal cord http://purl.obolibrary.org/obo/UBERON_0016550 spinal cord column The pronounced, dorsolaterally oriented ridge of grey matter in each lateral half of the spinal cord[MP]. the dorsal (more towards the back) grey matter of the spinal cord. It receives several types of sensory information from the body, including light touch, proprioception, and vibration. This information is sent from receptors of the skin, bones, and joints through sensory neurons whose cell bodies lie in the dorsal root ganglion[WP]. The dorsal region of the mature spinal cord contains neurons that process and relay sensory input[GO]. http://purl.obolibrary.org/obo/GO_0014074 response to purine-containing compound http://purl.obolibrary.org/obo/GO_1901698 response to nitrogen compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a purine-containing compound stimulus. http://purl.obolibrary.org/obo/UBERON_0002257 ventral horn of spinal cord http://purl.obolibrary.org/obo/UBERON_0016550 spinal cord column The ventral grey column of the spinal cord[MP]. The neurons of the ventral region of the mature spinal cord participate in motor output[GO]. http://purl.obolibrary.org/obo/GO_0014707 branchiomeric skeletal muscle development http://purl.obolibrary.org/obo/GO_0007519 skeletal muscle tissue development The process whose specific outcome is the progression of the branchiomeric skeletal muscle over time, from its formation to the mature structure. The branchiomeric muscle is derived from cranial mesoderm and controls facial expression, pharyngeal and laryngeal function, operating the jaw. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. Branchiomeric muscles of mammals correspond to the gill musculature of fish. http://purl.obolibrary.org/obo/UBERON_0002261 dorsal root of spinal cord http://purl.obolibrary.org/obo/UBERON_0009623 spinal nerve root The dorsal roots contain afferent sensory axons. The dorsal roots of each side continue outwards, along the way forming a dorsal root ganglion (also called a spinal ganglion). http://purl.obolibrary.org/obo/GO_0014711 regulation of branchiomeric skeletal muscle development http://purl.obolibrary.org/obo/GO_0048641 regulation of skeletal muscle tissue development Any process that modulates the frequency, rate or extent of branchiomeric skeletal muscle development. Branchiomeric skeletal muscle development is the process whose specific outcome is the progression of the branchiomeric skeletal muscle over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/UBERON_0002262 celiac ganglion http://purl.obolibrary.org/obo/UBERON_0003964 prevertebral ganglion The celiac ganglia are two large irregularly shaped masses of nerve tissue in the upper abdomen. Part of the sympathetic subdivision of the autonomic nervous system (ANS), the two celiac ganglia are the largest ganglia in the ANS, and they innervate most of the digestive tract. They have the appearance of lymph glands and are placed on either side of the midline in front of the crura of the diaphragm, close to the suprarenal glands (also called adrenal glands). The ganglion on the right side is placed behind the inferior vena cava. They are sometimes referred to as the semilunar ganglia or the solar ganglia. [WP,unvetted]. http://purl.obolibrary.org/obo/GO_0014712 positive regulation of branchiomeric skeletal muscle development http://purl.obolibrary.org/obo/GO_0048643 positive regulation of skeletal muscle tissue development Any process that activates, maintains or increases the frequency, rate or extent of branchiomeric skeletal muscle development. Branchiomeric skeletal muscle development is the process whose specific outcome is the progression of the branchiomeric skeletal muscle over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/UBERON_0002263 lentiform nucleus http://purl.obolibrary.org/obo/UBERON_0009663 telencephalic nucleus The lentiform nucleus or lenticular nucleus comprises the putamen and the globus pallidus within the basal ganglia. It is a large, cone-shaped mass of gray matter just lateral to the internal capsule. [WP,unvetted]. http://purl.obolibrary.org/obo/GO_0014713 negative regulation of branchiomeric skeletal muscle development http://purl.obolibrary.org/obo/GO_0048642 negative regulation of skeletal muscle tissue development Any process that stops, prevents, or reduces the frequency, rate or extent of branchiomeric skeletal muscle development. Branchiomeric skeletal muscle development is the process whose specific outcome is the progression of the branchiomeric skeletal muscle over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/UBERON_0002264 olfactory bulb http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure A bulbous anterior projection of the olfactory lobe that is the place of termination of the olfactory nerves and is especially well developed in lower vertebrates (as fishes)[BTO]. http://purl.obolibrary.org/obo/GO_0014717 regulation of satellite cell activation involved in skeletal muscle regeneration http://purl.obolibrary.org/obo/GO_0043416 regulation of skeletal muscle tissue regeneration Any process that modulates the frequency, rate or extent of satellite cell activation. The satellite cell activation is the process that initiates satellite cell division by causing it to move from quiescence to the G1 stage of the cell cycle. The cell swells and there are a number of other small changes. The cells then start to divide. Following cell division the cells will differentiate. http://purl.obolibrary.org/obo/UBERON_0002265 olfactory tract http://purl.obolibrary.org/obo/UBERON_0007702 tract of brain White matter tract that contains projections from the olfactory bulb to other parts of the brain. http://purl.obolibrary.org/obo/GO_0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration http://purl.obolibrary.org/obo/GO_0043415 positive regulation of skeletal muscle tissue regeneration Any process that activates, maintains or increases the frequency, rate or extent of activation of satellite cell involved in skeletal muscle regeneration. The activation of satellite cell is the process that initiates satellite cell division by causing it to move from quiescence to the G1 stage of the cell cycle. The cell swells and there are a number of other small changes. The cells then start to divide. Following cell division the cells will differentiate. http://purl.obolibrary.org/obo/UBERON_0002266 anterior olfactory nucleus http://purl.obolibrary.org/obo/UBERON_0009663 telencephalic nucleus Laminated structure lying caudal to the olfactory bulb. http://purl.obolibrary.org/obo/GO_0014719 skeletal muscle satellite cell activation http://purl.obolibrary.org/obo/GO_0001775 cell activation The change of a skeletal muscle satellite cell from a mitotically quiescent to a mitotically active state following exposure to some activating factor such as a cellular or soluble ligand. In adult muscle, satellite cells become activated to divide and differentiate in response to muscle damage. http://purl.obolibrary.org/obo/UBERON_0002268 olfactory organ http://purl.obolibrary.org/obo/UBERON_0000020 sense organ An organ that houses olfactory neurons and is responsible for the sense of smell. Examples include the vertebrate nose and the Drosophila dorsal organ. http://purl.obolibrary.org/obo/GO_0014722 regulation of skeletal muscle contraction by calcium ion signaling http://purl.obolibrary.org/obo/GO_0014819 regulation of skeletal muscle contraction Any process that modulates the frequency, rate or extent of skeletal muscle contraction by changing the calcium ion signals that trigger contraction. http://purl.obolibrary.org/obo/UBERON_0002275 reticular formation http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain A composite substructure of the brainstem that consists of the midbrain reticular formation, the pontine reticular formation and the medullary reticular formation ( Carpenter-1983 ). http://purl.obolibrary.org/obo/GO_0014725 regulation of extraocular skeletal muscle development http://purl.obolibrary.org/obo/GO_0048641 regulation of skeletal muscle tissue development Any process that modulates the frequency, rate or extent of extraocular skeletal muscle development. Extraocular skeletal muscle development is the process whose specific outcome is the progression of the extraocular skeletal muscle over time, from its formation to the mature structure. The extraocular muscle is derived from cranial mesoderm and controls eye movements. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. http://purl.obolibrary.org/obo/UBERON_0002276 lamina of spiral limbus http://purl.obolibrary.org/obo/UBERON_0000064 organ part The osseous spiral lamina consists of two plates of bone, and between these are the canals for the transmission of the filaments of the acoustic nerve. On the upper plate of that part of the lamina which is outside the vestibular membrane, the periosteum is thickened to form the limbus spiralis (or limbus laminæ spiralis), this ends externally in a concavity, the sulcus spiralis internus, which represents, on section, the form of the letter C. [WP,unvetted]. http://purl.obolibrary.org/obo/GO_0014726 negative regulation of extraocular skeletal muscle development http://purl.obolibrary.org/obo/GO_0048642 negative regulation of skeletal muscle tissue development Any process that stops, prevents, or reduces the frequency, rate or extent of extraocular skeletal muscle development. Extraocular skeletal muscle development is the process whose specific outcome is the progression of the extraocular skeletal muscle over time, from its formation to the mature structure. The extraocular muscle is derived from cranial mesoderm and controls eye movements. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. http://purl.obolibrary.org/obo/UBERON_0002278 perilymphatic space http://purl.obolibrary.org/obo/UBERON_0002553 anatomical cavity The fluid-filled space separating the membranous from the osseous labyrinth. http://purl.obolibrary.org/obo/GO_0014727 positive regulation of extraocular skeletal muscle development http://purl.obolibrary.org/obo/GO_0048643 positive regulation of skeletal muscle tissue development Any process that activates, maintains or increases the frequency, rate or extent of extraocular skeletal muscle development. Extraocular skeletal muscle development is the process whose specific outcome is the progression of the extraocular skeletal muscle over time, from its formation to the mature structure. The extraocular muscle is derived from cranial mesoderm and controls eye movements. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. http://purl.obolibrary.org/obo/UBERON_0002282 stria vascularis of cochlear duct http://purl.obolibrary.org/obo/UBERON_0010314 structure with developmental contribution from neural crest The upper portion of the spiral ligament contains numerous capillary loops and small blood vessels, and is termed the stria vascularis. It produces endolymph for the scala media, one of the three fluid-filled compartments of the cochlea. [WP,unvetted]. http://purl.obolibrary.org/obo/GO_0014733 regulation of skeletal muscle adaptation http://purl.obolibrary.org/obo/GO_0043502 regulation of muscle adaptation Any process in which skeletal muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities. http://purl.obolibrary.org/obo/UBERON_0002283 nail matrix http://purl.obolibrary.org/obo/UBERON_0000479 tissue Portion of tissue (or germinal matrix) upon which the nail rests, the part of the nail bed that extends beneath the nail root and contains nerves, lymph and blood vessels. The matrix is responsible for the production of the cells that become the nail plate. The width and thickness of the nail plate is determined by the size, length, and thickness of the matrix, while the shape of the fingertip itself determines if the nail plate is flat, arched, or hooked. The matrix will continue to grow as long as it receives nutrition and remains in a healthy condition. As new nail plate cells are incubated, they emerge from the matrix round and white to push older nail plate cells forward; and in this way yet older cells become compressed, flat, and translucent, making the pink colour of the capillaries in the nail bed below visible[WP]. http://purl.obolibrary.org/obo/GO_0014734 skeletal muscle hypertrophy http://purl.obolibrary.org/obo/GO_0043501 skeletal muscle adaptation The enlargement or overgrowth of all or part of an organ due to an increase in size (not length) of individual muscle fibers without cell division. In the case of skeletal muscle cells this happens due to the additional synthesis of sarcomeric proteins and assembly of myofibrils. http://purl.obolibrary.org/obo/UBERON_0002288 choroid plexus of third ventricle http://purl.obolibrary.org/obo/UBERON_0001886 choroid plexus Part of choroid plexus contained in the third ventricle. http://purl.obolibrary.org/obo/GO_0014741 negative regulation of muscle hypertrophy http://purl.obolibrary.org/obo/GO_0014743 regulation of muscle hypertrophy Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle hypertrophy. http://purl.obolibrary.org/obo/UBERON_0002290 choroid plexus of fourth ventricle http://purl.obolibrary.org/obo/UBERON_0006694 cerebellum vasculature Choroid plexus of the fourth ventricle. http://purl.obolibrary.org/obo/GO_0014742 positive regulation of muscle hypertrophy http://purl.obolibrary.org/obo/GO_0014743 regulation of muscle hypertrophy Any process that activates or increases the frequency, rate or extent of muscle hypertrophy. http://purl.obolibrary.org/obo/UBERON_0002291 central canal of spinal cord http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure Spinal cord structure that is part of the ventricular system and is filled with cerebral-spinal fluid and runs the length of the spinal cord. http://purl.obolibrary.org/obo/GO_0014743 regulation of muscle hypertrophy http://purl.obolibrary.org/obo/GO_0090257 regulation of muscle system process Any process that modulates the frequency, rate or extent of muscle hypertrophy. http://purl.obolibrary.org/obo/UBERON_0002294 biliary system http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision Organ system subdivision that consists of the organs and ducts that are involved in the production and transportation of bile. In most species this is the gallbladder and the bile ducts (biliary tree). http://purl.obolibrary.org/obo/GO_0014744 positive regulation of muscle adaptation http://purl.obolibrary.org/obo/GO_0043502 regulation of muscle adaptation Any process that activates or increases the frequency, rate or extent of muscle adaptation. http://purl.obolibrary.org/obo/UBERON_0002295 scala media http://purl.obolibrary.org/obo/UBERON_0013685 foramen of skull The division of the spiral canal of the cochlea that contains the organ of Corti (the neuroepithelial receptor organ for hearing). http://purl.obolibrary.org/obo/GO_0014745 negative regulation of muscle adaptation http://purl.obolibrary.org/obo/GO_0043502 regulation of muscle adaptation Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle adaptation. http://purl.obolibrary.org/obo/UBERON_0002299 alveolus of lung http://purl.obolibrary.org/obo/UBERON_0003215 alveolus Spherical outcropping of the respiratory bronchioles and primary site of gas exchange with the blood. Alveoli are particular to mammalian lungs. Different structures are involved in gas exchange in other vertebrates[WP]. http://purl.obolibrary.org/obo/GO_0014805 smooth muscle adaptation http://purl.obolibrary.org/obo/GO_0043500 muscle adaptation Any process in which smooth muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities. http://purl.obolibrary.org/obo/UBERON_0002301 layer of neocortex http://purl.obolibrary.org/obo/UBERON_8440004 laminar subdivision of the cortex One of the layers of the neocortex. These layers are defined by distinctive populations of cells based on somata size, shape, or density, that are aligned into sheets. http://purl.obolibrary.org/obo/GO_0014807 regulation of somitogenesis http://purl.obolibrary.org/obo/GO_0051239 regulation of multicellular organismal process Any process that modulates the frequency, rate or extent of somitogenesis. http://purl.obolibrary.org/obo/UBERON_0002302 myocardium of atrium http://purl.obolibrary.org/obo/UBERON_0002349 myocardium The atrial part of middle layer of the heart, comprised of involuntary muscle. http://purl.obolibrary.org/obo/GO_0014812 muscle cell migration http://purl.obolibrary.org/obo/GO_0016477 cell migration The orderly movement of a muscle cell from one site to another, often during the development of a multicellular organism. http://purl.obolibrary.org/obo/UBERON_0002303 juxtaglomerular apparatus http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure An anatomical structure which consists of juxtaglomerular cells, extraglomerular mesangial cells and the macula densa. The juxtaglomerular apparatus lies adjacent to the glomerulus and regulates kidney function by maintaining the blood flow to the kidney and the filtration rate[GO]. a microscopic structure in the kidney, which regulates the function of each nephron. The juxtaglomerular apparatus is named for its proximity to the glomerulus: it is found between the vascular pole of the renal corpuscle and the returning distal convoluted tubule of the same nephron. This location is critical to its function in regulating renal blood flow and glomerular filtration rate. The three cellular components of the apparatus are the macula densa, extraglomerular mesangial cells, and juxtaglomerular cells (also known as granular cells)[WP]. http://purl.obolibrary.org/obo/GO_0014816 skeletal muscle satellite cell differentiation http://purl.obolibrary.org/obo/GO_0035914 skeletal muscle cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a satellite cell. http://purl.obolibrary.org/obo/UBERON_0002304 layer of dentate gyrus http://purl.obolibrary.org/obo/UBERON_0022303 nervous system cell part layer One of the three layers of the dentate gyrus of the hippocampal formation. http://purl.obolibrary.org/obo/GO_0014819 regulation of skeletal muscle contraction http://purl.obolibrary.org/obo/GO_0006942 regulation of striated muscle contraction Any process that modulates the frequency, rate or extent of skeletal muscle contraction. http://purl.obolibrary.org/obo/UBERON_0002305 layer of hippocampus http://purl.obolibrary.org/obo/UBERON_0016548 central nervous system gray matter layer The layers of the laminar structure of the hippocampus. http://purl.obolibrary.org/obo/GO_0014821 phasic smooth muscle contraction http://purl.obolibrary.org/obo/GO_0006939 smooth muscle contraction A process in which force is generated within phasic smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the phasic smooth muscle, the muscle contraction occurs without an ordered sarcomeric structure. Phasic smooth muscle contraction occurs in a series of discrete contractions and relaxations. http://purl.obolibrary.org/obo/UBERON_0002306 nasal mucus http://purl.obolibrary.org/obo/UBERON_0016553 respiratory system mucus Mucus produced in the nasal cavity, by the respiratory segment of the nasal mucosa. http://purl.obolibrary.org/obo/GO_0014827 intestine smooth muscle contraction http://purl.obolibrary.org/obo/GO_0014831 gastro-intestinal system smooth muscle contraction A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the intestine. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The intestine is the section of the alimentary canal from the stomach to the anal canal. It includes the large intestine and small intestine. http://purl.obolibrary.org/obo/UBERON_0002307 choroid plexus of lateral ventricle http://purl.obolibrary.org/obo/UBERON_0001886 choroid plexus Part of choroid plexus contained in the lateral ventricle. http://purl.obolibrary.org/obo/GO_0014831 gastro-intestinal system smooth muscle contraction http://purl.obolibrary.org/obo/GO_0006939 smooth muscle contraction A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the gastro-intestinal system. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The gastro-intestinal system generally refers to the digestive structures stretching from the mouth to anus, but does not include the accessory glandular organs (liver, pancreas and biliary tract). http://purl.obolibrary.org/obo/UBERON_0002308 nucleus of brain http://purl.obolibrary.org/obo/UBERON_0000125 neural nucleus A neural nucleus that is part of the brain. http://purl.obolibrary.org/obo/GO_0014832 urinary bladder smooth muscle contraction http://purl.obolibrary.org/obo/GO_0014848 urinary tract smooth muscle contraction A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the urinary bladder. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The urinary bladder is a musculomembranous sac along the urinary tract. http://purl.obolibrary.org/obo/UBERON_0002310 hippocampus fimbria http://purl.obolibrary.org/obo/UBERON_0011215 central nervous system cell part cluster Regional part of fornix consisting of a prominent white matter structure adjacent to the hippocampus on the ventricular side continuous with the alveus. Near the splenium the fimbria separates from the hippocampus as the crus of the fornix. [adapted from Wikipedia] (MM: 2006-10-26). http://purl.obolibrary.org/obo/GO_0014833 skeletal muscle satellite stem cell asymmetric division http://purl.obolibrary.org/obo/GO_0098722 asymmetric stem cell division The asymmetric division of a skeletal muscle satellite stem cell to produce two daughter cells, one of which is destined to differentiate and the other to be a quiescent cell that restocks the satellite cell pool. http://purl.obolibrary.org/obo/UBERON_0002313 hippocampus pyramidal layer http://purl.obolibrary.org/obo/UBERON_0002305 layer of hippocampus A cytoarchitectural term denoting the layer of the hippocampus in which pyramidal cells are predominant. Its location is superficial to the Stratum oriens; it is deep to the Stratum radiatum in area CA1 and area CA2 and deep to the Stratum lucidum in area CA3 (Stephan-75) (NeuroNames). http://purl.obolibrary.org/obo/GO_0014834 skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration http://purl.obolibrary.org/obo/GO_0098727 maintenance of cell number Any process by which the number of skeletal muscle satellite cells in a skeletal muscle is maintained during muscle regeneration. There are at least three mechanisms by which this is achieved. Skeletal muscle satellite stem cell asymmetric division ensures satellite stem cell numbers are kept constant. Symmetric division of these cells amplifies the number of skeletal muscle satellite stem cells. Some adult skeletal muscle myoblasts (descendants of activated satellite cells) can develop back into quiescent satellite cells, replenishing the overall pool of satellite cells. http://purl.obolibrary.org/obo/UBERON_0002314 midbrain tectum http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain Dorsal part of the midbrain, consisting of the superior and inferior colliculi and the pretectal nuclei (MM). http://purl.obolibrary.org/obo/GO_0014835 myoblast differentiation involved in skeletal muscle regeneration http://purl.obolibrary.org/obo/GO_0045445 myoblast differentiation The process in which a relatively unspecialized satellite cell acquires specialized features of a myoblast. This occurs as part of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. http://purl.obolibrary.org/obo/UBERON_0002315 gray matter of spinal cord http://purl.obolibrary.org/obo/UBERON_0002020 gray matter The ridge-shaped grey matter of the spinal cord that extends longitudunally through the center of each half of the spinal cord, and are largely or entirely composed of nerve cell bodies and their dendrites and some supportive tissue. http://purl.obolibrary.org/obo/GO_0014839 myoblast migration involved in skeletal muscle regeneration http://purl.obolibrary.org/obo/GO_0051451 myoblast migration The process in which a myoblast migrates along an entire fiber to the site of injury. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. http://purl.obolibrary.org/obo/UBERON_0002316 white matter http://purl.obolibrary.org/obo/UBERON_0011215 central nervous system cell part cluster Neural tissue consisting of myelinated axons connecting grey matter areas of the central nervous system. http://purl.obolibrary.org/obo/GO_0014841 skeletal muscle satellite cell proliferation http://purl.obolibrary.org/obo/GO_0014856 skeletal muscle cell proliferation The multiplication or reproduction of satellite cells, resulting in the expansion of the cell population. Satellite cells are quiescent cells that are located between the basal lamina and the plasmalemma of the muscle fiber, which are the main contributors to postnatal muscle growth. In adult muscle, satellite cells become activated to divide and differentiate in response to muscle damage. http://purl.obolibrary.org/obo/UBERON_0002317 white matter of cerebellum http://purl.obolibrary.org/obo/UBERON_0002316 white matter Regional part of cerebellum consisting of the myelinated axons lying deep to the granule cell layer, excluding the deep cerebellar nuclei and the cerebellar peduncles. http://purl.obolibrary.org/obo/GO_0014842 regulation of skeletal muscle satellite cell proliferation http://purl.obolibrary.org/obo/GO_0014857 regulation of skeletal muscle cell proliferation Any process that modulates the frequency, rate or extent of skeletal muscle satellite cell proliferation. http://purl.obolibrary.org/obo/UBERON_0002318 white matter of spinal cord http://purl.obolibrary.org/obo/UBERON_0002316 white matter The regions of the spinal cord that are largely or entirely composed of myelinated nerve cell axons and contain few or no neural cell bodies or dendrites. http://purl.obolibrary.org/obo/GO_0014848 urinary tract smooth muscle contraction http://purl.obolibrary.org/obo/GO_0006939 smooth muscle contraction A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the urinary tract. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The urinary tract consists of organs of the body that produce and discharge urine. These include the kidneys, ureters, bladder, and urethra. http://purl.obolibrary.org/obo/UBERON_0002319 mesangium http://purl.obolibrary.org/obo/UBERON_0000119 cell layer The inner layer of the glomerulus, within the basement membrane surrounding the glomerular capillaries. http://purl.obolibrary.org/obo/GO_0014849 ureter smooth muscle contraction http://purl.obolibrary.org/obo/GO_0014848 urinary tract smooth muscle contraction A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the ureter. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The ureter is one of a pair of thick-walled tubes that transports urine from the kidney pelvis to the urinary bladder. http://purl.obolibrary.org/obo/UBERON_0002320 glomerular mesangium http://purl.obolibrary.org/obo/UBERON_0003891 stroma A thin membrane which helps to support the capillary loops in a renal glomerulus. It is connective tissue composed of mesangial cells - myofibroblasts phenotypically related to vascular smooth muscle cells (muscle, smooth, vascular), phagocytes and the mesangial extracellular matrix. http://purl.obolibrary.org/obo/GO_0014852 regulation of skeletal muscle contraction by neural stimulation via neuromuscular junction http://purl.obolibrary.org/obo/GO_0014819 regulation of skeletal muscle contraction Any process that modulates the frequency, rate or extent of skeletal muscle contraction by variation of the pattern of stimulation by nervous system. http://purl.obolibrary.org/obo/UBERON_0002321 extraglomerular mesangium http://purl.obolibrary.org/obo/UBERON_0003891 stroma The tissue comprised of mesangial cells that fill the triangular space between the macula densa and the afferent and efferent arterioles of the juxtaglomerular apparatus. http://purl.obolibrary.org/obo/GO_0014853 regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction http://purl.obolibrary.org/obo/GO_0098815 modulation of excitatory postsynaptic potential Any process, involved in skeletal muscle contraction, that modulates the establishment or extent of the excitatory postsynaptic potential (EPSP). Excitatory postsynaptic potential (EPSP) is a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential. http://purl.obolibrary.org/obo/UBERON_0002322 periventricular nucleus http://purl.obolibrary.org/obo/UBERON_0002308 nucleus of brain A thin sheet of small neurons located in the wall of the third ventricle, a composite structure of the hypothalamus. http://purl.obolibrary.org/obo/GO_0014855 striated muscle cell proliferation http://purl.obolibrary.org/obo/GO_0033002 muscle cell proliferation The multiplication or reproduction of striated muscle cells, resulting in the expansion of a cell population. Striated muscles contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle. http://purl.obolibrary.org/obo/UBERON_0002323 coelemic cavity lumen http://purl.obolibrary.org/obo/UBERON_0002553 anatomical cavity The cavity within the body of all animals higher than the coelenterates and certain primitive worms, formed by the splitting of the embryonic mesoderm into two layers. In mammals it forms the peritoneal, pleural, and pericardial cavities. http://purl.obolibrary.org/obo/GO_0014856 skeletal muscle cell proliferation http://purl.obolibrary.org/obo/GO_0014855 striated muscle cell proliferation The multiplication or reproduction of skeletal muscle cells, resulting in the expansion of a cell population. http://purl.obolibrary.org/obo/UBERON_0002324 muscle of back http://purl.obolibrary.org/obo/UBERON_0005174 dorsal region element Any muscle organ that is part of a back [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0014857 regulation of skeletal muscle cell proliferation http://purl.obolibrary.org/obo/GO_0042127 regulation of cell population proliferation Any process that modulates the frequency, rate or extent of skeletal muscle cell proliferation. http://purl.obolibrary.org/obo/UBERON_0002325 epithelium of urethra http://purl.obolibrary.org/obo/UBERON_0006555 excretory tube The urethra is a renal system organ that carries urine from the bladder to outside the body. The epithelium is the tubular, planar layer of cells through which the urine passes.. http://purl.obolibrary.org/obo/GO_0014858 positive regulation of skeletal muscle cell proliferation http://purl.obolibrary.org/obo/GO_0014857 regulation of skeletal muscle cell proliferation Any process that activates or increases the frequency, rate or extent of skeletal muscle cell proliferation. http://purl.obolibrary.org/obo/UBERON_0002326 lamina propria of urethra http://purl.obolibrary.org/obo/UBERON_0000030 lamina propria A lamina propria that is part of a urethra [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0014859 negative regulation of skeletal muscle cell proliferation http://purl.obolibrary.org/obo/GO_0014857 regulation of skeletal muscle cell proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle cell proliferation. http://purl.obolibrary.org/obo/UBERON_0002328 notochord http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure A flexible rod-shaped body found in embryos of all chordates. It is composed of cells derived from the mesoderm and defines the primitive axis of the embryo. In some chordates, it persists throughout life as the main axial support of the body, while in most vertebrates it becomes the nucleus pulposus of the intervertebral disc. The notochord is found ventral to the neural tube. http://purl.obolibrary.org/obo/GO_0014860 neurotransmitter secretion involved in regulation of skeletal muscle contraction http://purl.obolibrary.org/obo/GO_0007269 neurotransmitter secretion The regulated release of neurotransmitter into the synaptic cleft involved in skeletal muscle contraction. A neurotransmitter is any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell. Among the many substances that have the properties of a neurotransmitter are acetylcholine, noradrenaline, adrenaline, dopamine, glycine, gamma aminobutyrate, glutamic acid, substance P, enkephalins, endorphins and serotonin. http://purl.obolibrary.org/obo/UBERON_0002329 somite http://purl.obolibrary.org/obo/UBERON_0007503 epithelial vesicle Somites are spheres of epithelial cells that form sequentially along the anterior-posterior axis of the embryo through mesenchymal to epithelial transition of the presomitic mesoderm. http://purl.obolibrary.org/obo/GO_0014861 regulation of skeletal muscle contraction via regulation of action potential http://purl.obolibrary.org/obo/GO_0098900 regulation of action potential Any process that modulates the frequency, rate or extent of skeletal muscle contraction by depolarization of muscle membrane and ionic fluxes. http://purl.obolibrary.org/obo/UBERON_0002331 umbilical cord http://purl.obolibrary.org/obo/UBERON_0000478 extraembryonic structure The connecting cord from the developing embryo to the placenta. http://purl.obolibrary.org/obo/GO_0014866 skeletal myofibril assembly http://purl.obolibrary.org/obo/GO_0030239 myofibril assembly The process whose specific outcome is the progression of the skeletal myofibril over time, from its formation to the mature structure. A skeletal myofibril is a myofibril specific to skeletal muscle cells. http://purl.obolibrary.org/obo/UBERON_0002333 pulmonary trunk http://purl.obolibrary.org/obo/UBERON_0001637 artery An arterial trunk which is continuous with the heart and branches into the pulmonary arteries. http://purl.obolibrary.org/obo/GO_0014872 myoblast division http://purl.obolibrary.org/obo/GO_0051301 cell division The process resulting in the physical partitioning and separation of a myoblast into daughter cells. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. http://purl.obolibrary.org/obo/UBERON_0002334 submandibular duct http://purl.obolibrary.org/obo/UBERON_0001837 duct of salivary gland The duct of the submadibular gland that opens at the sublingual papilla near the frenulum of the tongue. http://purl.obolibrary.org/obo/GO_0014878 response to electrical stimulus involved in regulation of muscle adaptation http://purl.obolibrary.org/obo/GO_0051602 response to electrical stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus. This process occurs as part of the regulation of muscle adaptation. http://purl.obolibrary.org/obo/UBERON_0002335 macula densa http://purl.obolibrary.org/obo/UBERON_0004211 nephron epithelium The macula densa is an area of specialized cells in the distal tubule that makes contact with the vascular pole of the glomerulus[GO]. http://purl.obolibrary.org/obo/GO_0014887 cardiac muscle adaptation http://purl.obolibrary.org/obo/GO_0014888 striated muscle adaptation The process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. http://purl.obolibrary.org/obo/UBERON_0002337 endometrial stroma http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure The layer of connective tissue comprised of the endometrial lining of the uterus which fluctuates in thickness throughout the menstrual cycle. http://purl.obolibrary.org/obo/GO_0014888 striated muscle adaptation http://purl.obolibrary.org/obo/GO_0043500 muscle adaptation Any process in which striated muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities. http://purl.obolibrary.org/obo/UBERON_0002338 lamina propria of bronchus http://purl.obolibrary.org/obo/UBERON_0000031 lamina propria of trachea A lamina propria that is part of a bronchus [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0014895 smooth muscle hypertrophy http://purl.obolibrary.org/obo/GO_0014805 smooth muscle adaptation The enlargement or overgrowth of all or part of an organ due to an increase in size of its smooth muscle cells without cell division. Physiological hypertrophy is a normal process during development, and can also occur in mature structures on demand. In the uterus, smooth muscle cells undergo hypertrophy during pregnancy. http://purl.obolibrary.org/obo/UBERON_0002339 epithelium of lobar bronchus http://purl.obolibrary.org/obo/UBERON_0002031 epithelium of bronchus The tissue made up of epithelial cells that lines the inside of the lobar bronchus. http://purl.obolibrary.org/obo/GO_0014901 satellite cell activation involved in skeletal muscle regeneration http://purl.obolibrary.org/obo/GO_0014719 skeletal muscle satellite cell activation The process that initiates skeletal muscle satellite cell division by causing it to move from quiescence to the G1 stage of the cell cycle. The cell swells and there are a number of other small changes. The cells then start to divide. Following cell division the cells will differentiate. In adult muscle, satellite cells become activated to divide and differentiate in response to muscle damage. http://purl.obolibrary.org/obo/UBERON_0002341 epithelium of segmental bronchus http://purl.obolibrary.org/obo/UBERON_0006934 sensory epithelium An epithelium that is part of a segmental bronchus [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0014904 myotube cell development http://purl.obolibrary.org/obo/GO_0055002 striated muscle cell development The process aimed at the progression of a myotube cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse. http://purl.obolibrary.org/obo/UBERON_0002342 neural crest http://purl.obolibrary.org/obo/UBERON_0010316 germ layer / neural crest A specialized region of ectoderm found between the neural ectoderm (neural plate) and non-neural ectoderm and composed of highly migratory pluripotent cells that delaminate in early embryonic development from the dorsal neural tube and give rise to an astounding variety of differentiated cell types[MP]. http://purl.obolibrary.org/obo/GO_0014906 myotube cell development involved in skeletal muscle regeneration http://purl.obolibrary.org/obo/GO_0014904 myotube cell development The process aimed at the progression of a myotube cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. This occurs as part of the process of skeletal muscle regeneration. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse. http://purl.obolibrary.org/obo/UBERON_0002343 abdomen musculature http://purl.obolibrary.org/obo/UBERON_0004479 musculature of trunk Set of all muscles in abdomen. http://purl.obolibrary.org/obo/GO_0014908 myotube differentiation involved in skeletal muscle regeneration http://purl.obolibrary.org/obo/GO_0014902 myotube differentiation The process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotube differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual myotubes can fuse to form bigger myotubes and start to contract. This process occurs as part of the process of skeletal muscle regeneration. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse. http://purl.obolibrary.org/obo/UBERON_0002345 descending thoracic aorta http://purl.obolibrary.org/obo/UBERON_0013522 subdivision of tube The part of the aorta that extends from the arch of the aorta to the diaphragm, and from which arises numerous branches that supply oxygenated blood to the chest cage and the organs within the chest. http://purl.obolibrary.org/obo/GO_0014909 smooth muscle cell migration http://purl.obolibrary.org/obo/GO_0014812 muscle cell migration The orderly movement of a smooth muscle cell from one site to another, often during the development of a multicellular organism. http://purl.obolibrary.org/obo/UBERON_0002346 neurectoderm http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure Embryonic ectoderm that gives rise to nervous tissue. http://purl.obolibrary.org/obo/GO_0014910 regulation of smooth muscle cell migration http://purl.obolibrary.org/obo/GO_0030334 regulation of cell migration Any process that modulates the frequency, rate or extent of smooth muscle cell migration. http://purl.obolibrary.org/obo/UBERON_0002347 thoracic vertebra http://purl.obolibrary.org/obo/UBERON_0015008 thoracic vertebra endochondral element A thoracic vertebra endochondral element that is composed primarily of a bone tissue. http://purl.obolibrary.org/obo/GO_0014911 positive regulation of smooth muscle cell migration http://purl.obolibrary.org/obo/GO_0014910 regulation of smooth muscle cell migration Any process that activates, maintains or increases the frequency, rate or extent of smooth muscle cell migration. http://purl.obolibrary.org/obo/UBERON_0002350 conducting system of heart http://purl.obolibrary.org/obo/UBERON_0010131 conducting tissue of heart The cardiac conduction system consists of specialized cardiomyocytes that regulate the frequency of heart beat[GO]. http://purl.obolibrary.org/obo/GO_0014912 negative regulation of smooth muscle cell migration http://purl.obolibrary.org/obo/GO_0014910 regulation of smooth muscle cell migration Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell migration. http://purl.obolibrary.org/obo/UBERON_0002352 atrioventricular node http://purl.obolibrary.org/obo/UBERON_0010131 conducting tissue of heart An area of conducting tissue between the atria and the ventricles of the heart that conducts the normal electrical impulse from the atria to the ventricles. http://purl.obolibrary.org/obo/GO_0015106 bicarbonate transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity Enables the transfer of bicarbonate from one side of a membrane to the other. Bicarbonate is the hydrogencarbonate ion, HCO3-. http://purl.obolibrary.org/obo/UBERON_0002353 bundle of His http://purl.obolibrary.org/obo/UBERON_0018649 cardiac muscle tissue of ventricle A part of the His-Purkinje system that transmits signals from the AV node to the cardiac Purkinje fibers[GO]. http://purl.obolibrary.org/obo/GO_0015125 bile acid transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0170055 lipid transmembrane transporter activity Enables the transfer of bile acid from one side of a membrane to the other. Bile acids are any of a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine. http://purl.obolibrary.org/obo/UBERON_0002354 cardiac Purkinje fiber http://purl.obolibrary.org/obo/UBERON_0018649 cardiac muscle tissue of ventricle The cardiac Purkinje fiber is part of the cardiac conduction system that receives signals from the bundle of His and innervates the ventricular cardiac muscle. http://purl.obolibrary.org/obo/GO_0015144 carbohydrate transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity Enables the transfer of carbohydrate from one side of a membrane to the other. http://purl.obolibrary.org/obo/UBERON_0002355 pelvic region of trunk http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision The lower segment of the trunk, inferioposterior to the abdomen proper, in the transition area between the trunk and the lower limbs. http://purl.obolibrary.org/obo/GO_0015145 monosaccharide transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0051119 sugar transmembrane transporter activity Enables the transfer of a monosaccharide from one side of a membrane to the other. http://purl.obolibrary.org/obo/UBERON_0002357 serous pericardium http://purl.obolibrary.org/obo/UBERON_0000042 serous membrane Serous membrane which is divided into parietal and visceral serous pericardium. http://purl.obolibrary.org/obo/GO_0015159 polysaccharide transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022884 macromolecule transmembrane transporter activity Enables the transfer of polysaccharides from one side of a membrane to the other. A polysaccharide is a polymer of many (typically more than 10) monosaccharide residues linked glycosidically. http://purl.obolibrary.org/obo/UBERON_0002359 fibrous pericardium http://purl.obolibrary.org/obo/UBERON_0005181 thoracic segment organ Membrane organ which is attached to the pericardial sac proper and the central tendon of diaphragm and is continuous with the pretracheal fascia.[FMA]. http://purl.obolibrary.org/obo/GO_0015187 glycine transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0015175 neutral L-amino acid transmembrane transporter activity Enables the transfer of glycine from one side of a membrane to the other. Glycine is aminoethanoic acid. http://purl.obolibrary.org/obo/UBERON_0002360 meninx http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure Membrane organ that surrounds the brain and the spinal cord. http://purl.obolibrary.org/obo/GO_0015250 water channel activity http://purl.obolibrary.org/obo/GO_0015267 channel activity Enables the energy-independent facilitated diffusion of water through a transmembrane aqueous pore or channel. http://purl.obolibrary.org/obo/UBERON_0002361 pia mater http://purl.obolibrary.org/obo/UBERON_0000391 leptomeninx The innermost layer of the leptomeninges, consisting of a delicate membrane closely covering the surface of the brain and spinal cord,and lying under the arachnoid membrane. The pia, unlike the arachnoid, extends into the sulci in gyrencephalic animals. http://purl.obolibrary.org/obo/GO_0015252 proton channel activity http://purl.obolibrary.org/obo/GO_0015078 proton transmembrane transporter activity Enables the facilitated diffusion of a hydrogen ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. http://purl.obolibrary.org/obo/UBERON_0002362 arachnoid mater http://purl.obolibrary.org/obo/UBERON_0000391 leptomeninx A think avascular meningeal layer, between the pia mater and the dural mater. It is separated from the pia mater by the subarachnoid space. http://purl.obolibrary.org/obo/GO_0015267 channel activity http://purl.obolibrary.org/obo/GO_0022803 passive transmembrane transporter activity Enables the energy-independent facilitated diffusion of a solute through a transmembrane aqueous pore or channel. Stereospecificity is not exhibited but this transport may be specific for a particular molecular species or class of molecules. http://purl.obolibrary.org/obo/UBERON_0002363 dura mater http://purl.obolibrary.org/obo/UBERON_0002360 meninx Thick, fibrous meningeal covering surrounding the brain and spinal cord. It is the outermost of the three meningeal coverings. It consists of two layers: the periosteal dura linking the inner surface of the skull and the meningeal dura that lies above the arachnoid dural membrane. The meningeal layer draws away from the periosteal layer and certain locations to form the dural reflections. http://purl.obolibrary.org/obo/GO_0015269 calcium-activated potassium channel activity http://purl.obolibrary.org/obo/GO_0005267 potassium channel activity Enables the transmembrane transfer of a potassium cation by a channel that opens when a calcium cation has been bound by the channel complex or one of its constituent parts. http://purl.obolibrary.org/obo/UBERON_0002365 exocrine gland http://purl.obolibrary.org/obo/UBERON_0002530 gland A gland that secretes products (excluding hormones and other chemical messengers) into ducts (duct glands) which lead directly into the external environment[WP]. Typical exocrine glands include sweat glands, salivary glands, mammary glands, stomach, liver, pancreas. http://purl.obolibrary.org/obo/GO_0015277 kainate selective glutamate receptor activity http://purl.obolibrary.org/obo/GO_0015280 ligand-gated sodium channel activity An ionotropic glutamate receptor activity that exhibits fast gating by glutamate, acts by opening a cation channel permeable to sodium and potassium, and for which kainate is an agonist. http://purl.obolibrary.org/obo/UBERON_0002374 metacarpal bone http://purl.obolibrary.org/obo/UBERON_0015042 manual digit metacarpus endochondral element A bone that is part of the metacarpal skeleton. http://purl.obolibrary.org/obo/GO_0015280 ligand-gated sodium channel activity http://purl.obolibrary.org/obo/GO_0099094 ligand-gated monoatomic cation channel activity Enables the transmembrane transfer of a sodium ion by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts. http://purl.obolibrary.org/obo/UBERON_0002376 cranial muscle http://purl.obolibrary.org/obo/UBERON_0010959 craniocervical muscle Any skeletal muscle that is part of the head region. http://purl.obolibrary.org/obo/GO_0015355 secondary active monocarboxylate transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0015291 secondary active transmembrane transporter activity Catalysis of the movement of a monocarboxylate, any compound containing a single carboxyl group (COOH or COO-), by uniport, symport or antiport across a membrane by a carrier-mediated mechanism. http://purl.obolibrary.org/obo/UBERON_0002377 muscle of neck http://purl.obolibrary.org/obo/UBERON_0010959 craniocervical muscle Any muscle that is part of the cervical (neck) region. http://purl.obolibrary.org/obo/GO_0015636 short-chain fatty acid transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0015245 fatty acid transmembrane transporter activity Enables the transfer of short-chain fatty acids from one side of a membrane to the other. A short-chain fatty acid has an aliphatic tail containing fewer than 6 carbons. http://purl.obolibrary.org/obo/UBERON_0002378 muscle of abdomen http://purl.obolibrary.org/obo/UBERON_0005172 abdomen element Muscle (organ) which is a part of the abdomen. Examples: external oblique, rectus abdominis. http://purl.obolibrary.org/obo/GO_0015665 alcohol transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity Enables the transfer of an alcohol from one side of a membrane to the other. An alcohol is any carbon compound that contains a hydroxyl group. http://purl.obolibrary.org/obo/UBERON_0002380 trapezius muscle http://purl.obolibrary.org/obo/UBERON_0010313 neural crest-derived structure A large superficial muscle that extends longitudinally from the occipital bone to the lower thoracic vertebrae and laterally to the spine of the scapula (shoulder blade). Its functions are to move the scapulae and support the arm. The trapezius has three functional regions: the superior region (descending part), which supports the weight of the arm; the intermediate region (transverse part), which retracts the scapulae; and the inferior region (ascending part), which medially rotates and depresses the scapulae. [WP,unvetted]. http://purl.obolibrary.org/obo/GO_0015669 gas transport http://purl.obolibrary.org/obo/GO_0006810 transport The directed movement of substances that are gaseous in normal living conditions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0015695 organic cation transport http://purl.obolibrary.org/obo/GO_0006810 transport The directed movement of organic cations into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organic cations are atoms or small molecules with a positive charge which contain carbon in covalent linkage. http://purl.obolibrary.org/obo/UBERON_0002381 pectoralis major http://purl.obolibrary.org/obo/UBERON_0001495 pectoral muscle The pectoralis major is a thick, fan-shaped muscle, situated at the upper front of the chest wall. It makes up the bulk of the chest muscles in the male and lies under the breast in the female. Underneath the pectoralis major is the pectoralis minor, a thin, triangular muscle. [WP,unvetted]. http://purl.obolibrary.org/obo/GO_0015701 bicarbonate transport http://purl.obolibrary.org/obo/GO_0015711 organic anion transport The directed movement of bicarbonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/UBERON_0002392 nasolacrimal duct http://purl.obolibrary.org/obo/UBERON_0000058 duct The paired channels leading from the lacrimal sacs to the inferior meatus of the nose, through which tears are conducted through the nasal cavity. http://purl.obolibrary.org/obo/GO_0015721 bile acid and bile salt transport http://purl.obolibrary.org/obo/GO_0006869 lipid transport The directed movement of bile acid and bile salts into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/UBERON_0002393 pharyngotympanic tube http://purl.obolibrary.org/obo/UBERON_0000062 organ Organ with organ cavity which connects the cavity of the middle ear to the cavity of the pharynx. Examples: There are only two pharyngotympanic tubes, the right and the left pharyngotympanic tubes.[FMA]. http://purl.obolibrary.org/obo/GO_0015749 monosaccharide transmembrane transport http://purl.obolibrary.org/obo/GO_0034219 carbohydrate transmembrane transport The process in which a monosaccharide is transported across a lipid bilayer, from one side of a membrane to the other. Monosaccharides are the simplest carbohydrates; they are polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides. http://purl.obolibrary.org/obo/UBERON_0002396 vomer http://purl.obolibrary.org/obo/UBERON_0012071 palate bone The triangular flat bone of the nasal septum. http://purl.obolibrary.org/obo/GO_0015774 polysaccharide transport http://purl.obolibrary.org/obo/GO_0008643 carbohydrate transport The directed movement of polysaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A polysaccharide is a polymer of many (typically more than 10) monosaccharide residues linked glycosidically. http://purl.obolibrary.org/obo/UBERON_0002400 parietal pleura http://purl.obolibrary.org/obo/UBERON_0004923 organ component layer The outer serous membrane of the pulmonary pleural. http://purl.obolibrary.org/obo/GO_0015800 acidic amino acid transport http://purl.obolibrary.org/obo/GO_0006865 amino acid transport The directed movement of acidic amino acids, amino acids with a pH below 7, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/UBERON_0002401 visceral pleura http://purl.obolibrary.org/obo/UBERON_0022350 visceral serous membrane The inner serous membrane of the pulmonary pleural. The visceral pleura lines the lungs. http://purl.obolibrary.org/obo/GO_0015801 aromatic amino acid transport http://purl.obolibrary.org/obo/GO_0071705 nitrogen compound transport The directed movement of aromatic amino acids, amino acids with aromatic ring, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/UBERON_0002402 pleural cavity http://purl.obolibrary.org/obo/UBERON_0035809 serous cavity The fluid-filled cavity that lies between the visceral and parietal pleurae. http://purl.obolibrary.org/obo/GO_0015802 basic amino acid transport http://purl.obolibrary.org/obo/GO_0006865 amino acid transport The directed movement of basic amino acids, amino acids with a pH above 7, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0015807 L-amino acid transport http://purl.obolibrary.org/obo/GO_0006865 amino acid transport The directed movement of L-enantiomer amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/UBERON_0002406 pericardial sac http://purl.obolibrary.org/obo/UBERON_0005906 serous sac A double-walled sac containing the heart and the roots of the great vessels. http://purl.obolibrary.org/obo/GO_0015812 gamma-aminobutyric acid transport http://purl.obolibrary.org/obo/GO_0006865 amino acid transport The directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/UBERON_0002408 parietal serous pericardium http://purl.obolibrary.org/obo/UBERON_0022351 parietal serous membrane Parietal serous membrane which is part of the pericardium and forms the outer layer of the pericardial sac. http://purl.obolibrary.org/obo/GO_0015816 glycine transport http://purl.obolibrary.org/obo/GO_0015695 organic cation transport The directed movement of glycine, aminoethanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/UBERON_0002409 pericardial fluid http://purl.obolibrary.org/obo/UBERON_0036217 coelomic fluid Transudate contained in the pericardial cavity.[FMA]. http://purl.obolibrary.org/obo/UBERON_0002412 vertebra http://purl.obolibrary.org/obo/UBERON_0010913 vertebral element The ossified form of a vertebral element, a skeletal element that forms around the notochord and is part of the vertebral column. http://purl.obolibrary.org/obo/GO_0015849 organic acid transport http://purl.obolibrary.org/obo/GO_0006810 transport The directed movement of organic acids, any acidic compound containing carbon in covalent linkage, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/UBERON_0002413 cervical vertebra http://purl.obolibrary.org/obo/UBERON_0015007 cervical vertebra endochondral element A vertebra that is located in the cervical region of the vertebral column. http://purl.obolibrary.org/obo/GO_0015866 ADP transport http://purl.obolibrary.org/obo/GO_0015868 purine ribonucleotide transport The directed movement of ADP, adenosine diphosphate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/UBERON_0002414 lumbar vertebra http://purl.obolibrary.org/obo/UBERON_0015009 lumbar vertebra endochondral element Large vertebra of the movable part of the vertebral column, characterized by the absence of the foramen transversarium within the transverse process, and by the absence of facets on the sides of the body. http://purl.obolibrary.org/obo/GO_0015868 purine ribonucleotide transport http://purl.obolibrary.org/obo/GO_1901264 carbohydrate derivative transport The directed movement of a purine ribonucleotide, any compound consisting of a purine ribonucleoside (a purine organic base attached to a ribose sugar) esterified with (ortho)phosphate, into, out of or within a cell. http://purl.obolibrary.org/obo/UBERON_0002415 tail http://purl.obolibrary.org/obo/UBERON_0011676 subdivision of organism along main body axis An external caudal extension of the body. In chordates, the tail is post-anal, in other animals the anus ends in the tail. http://purl.obolibrary.org/obo/GO_0015870 acetylcholine transport http://purl.obolibrary.org/obo/GO_1901374 acetate ester transport The directed movement of acetylcholine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Acetylcholine is an acetic acid ester of the organic base choline and functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions. http://purl.obolibrary.org/obo/UBERON_0002417 abdominal segment of trunk http://purl.obolibrary.org/obo/UBERON_0011676 subdivision of organism along main body axis The abdominal segment of the torso. http://purl.obolibrary.org/obo/GO_0015872 dopamine transport http://purl.obolibrary.org/obo/GO_0051937 catecholamine transport The directed movement of dopamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Dopamine is a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline. http://purl.obolibrary.org/obo/UBERON_0002418 cartilage tissue http://purl.obolibrary.org/obo/UBERON_0004755 skeletal tissue Skeletal tissue that is avascular, rich in glycosaminoglycans (GAGs) and typically includes chondrocytes within isolated lacunae. Cartilage tissue is deposited by chondroblasts. http://purl.obolibrary.org/obo/GO_0015874 norepinephrine transport http://purl.obolibrary.org/obo/GO_0051937 catecholamine transport The directed movement of norepinephrine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Norepinephrine (3,4-dihydroxyphenyl-2-aminoethanol) is a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine. http://purl.obolibrary.org/obo/UBERON_0002419 skin gland http://purl.obolibrary.org/obo/UBERON_0006003 integumentary adnexa A gland that is part of a skin of body [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0015912 short-chain fatty acid transport http://purl.obolibrary.org/obo/GO_0015908 fatty acid transport The directed movement of short-chain fatty acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A short-chain fatty acid has an aliphatic tail containing fewer than 6 carbons. http://purl.obolibrary.org/obo/UBERON_0002421 hippocampal formation http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain Hippocampus (proper) plus dentate gyrus and subiculum[definition derived from NIF comments and ontology alignment]. http://purl.obolibrary.org/obo/GO_0015913 short-chain fatty acid transmembrane transport http://purl.obolibrary.org/obo/GO_0015912 short-chain fatty acid transport The directed movement of short-chain fatty acids into a cell or organelle. A short-chain fatty acid has an aliphatic tail containing fewer than 6 carbons. http://purl.obolibrary.org/obo/UBERON_0002422 fourth ventricle http://purl.obolibrary.org/obo/UBERON_0004086 brain ventricle Part of the ventricular system of the brain, forming a single large irregularly shaped cavity located on the midline of the rhombencephalon, between the medulla, pons and the isthmus ventrally and the cerebellum dorsally. It is continuous with the cerebral aqueduct anteriorally and the central canal of the spinal cord posteriorly. It communicates with the subarachnoid space through its lateral and median apertures. http://purl.obolibrary.org/obo/GO_0015979 photosynthesis http://purl.obolibrary.org/obo/GO_0008152 metabolic process The synthesis by organisms of organic chemical compounds, especially carbohydrates, from carbon dioxide (CO2) using energy obtained from light rather than from the oxidation of chemical compounds. http://purl.obolibrary.org/obo/UBERON_0002423 hepatobiliary system http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision The part of the digestive system that contains the liver and the biliary system. http://purl.obolibrary.org/obo/GO_0016031 tRNA import into mitochondrion http://purl.obolibrary.org/obo/GO_0035927 RNA import into mitochondrion The process in which a tRNA is transported from the cytosol into the mitochondrial matrix. http://purl.obolibrary.org/obo/UBERON_0002424 oral epithelium http://purl.obolibrary.org/obo/UBERON_0003929 digestive tract epithelium An epithelium that is part of the mouth and lines the oral cavity, typically stratified squamous, and may be para-, ortho- or non- keratinized. Primary barrier between oral environment and deeper tissues. http://purl.obolibrary.org/obo/GO_0016048 detection of temperature stimulus http://purl.obolibrary.org/obo/GO_0009582 detection of abiotic stimulus The series of events in which a temperature stimulus (hot or cold) is received and converted into a molecular signal. http://purl.obolibrary.org/obo/UBERON_0002425 visceral serous pericardium http://purl.obolibrary.org/obo/UBERON_0022350 visceral serous membrane Visceral serous membrane which is continuous with the parietal serous pericardium and is attached to the myocardium[FMA]. http://purl.obolibrary.org/obo/GO_0016053 organic acid biosynthetic process http://purl.obolibrary.org/obo/GO_0044283 small molecule biosynthetic process The chemical reactions and pathways resulting in the formation of organic acids, any acidic compound containing carbon in covalent linkage. http://purl.obolibrary.org/obo/UBERON_0002426 chest muscle http://purl.obolibrary.org/obo/UBERON_0005175 chest organ Any muscle organ that is part of a chest [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0016054 organic acid catabolic process http://purl.obolibrary.org/obo/GO_0044282 small molecule catabolic process The chemical reactions and pathways resulting in the breakdown of organic acids, any acidic compound containing carbon in covalent linkage. http://purl.obolibrary.org/obo/UBERON_0002427 arm skin http://purl.obolibrary.org/obo/UBERON_0003531 forelimb skin A zone of skin that is part of an arm [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0002428 limb bone http://purl.obolibrary.org/obo/UBERON_0015061 limb endochondral element A bone that is part of a limb [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0002429 cervical lymph node http://purl.obolibrary.org/obo/UBERON_0000029 lymph node Cervical lymph nodes are lymph nodes found in the neck. [WP,unvetted]. http://purl.obolibrary.org/obo/UBERON_0002435 striatum http://purl.obolibrary.org/obo/UBERON_0011300 gray matter of telencephalon A region of the forebrain consisting of the caudate nucleus, putamen and fundus striati.[GO]. http://purl.obolibrary.org/obo/UBERON_0002437 cerebral hemisphere white matter http://purl.obolibrary.org/obo/UBERON_0011299 white matter of telencephalon White matter that is part of a cerebral hemisphere. http://purl.obolibrary.org/obo/UBERON_0002439 myenteric nerve plexus http://purl.obolibrary.org/obo/UBERON_0000429 enteric plexus One of two ganglionated neural networks which together form the enteric nervous system. The myenteric (Auerbach's) plexus is located between the longitudinal and circular muscle layers of the gut. Its neurons project to the circular muscle, to other myenteric ganglia, to submucosal ganglia, or directly to the epithelium, and play an important role in regulating and patterning gut motility. http://purl.obolibrary.org/obo/UBERON_0002441 cervicothoracic ganglion http://purl.obolibrary.org/obo/UBERON_0001991 cervical ganglion The group of neurons formed by the fusion of the inferior cervical and first thoracic ganglia. http://purl.obolibrary.org/obo/UBERON_0002443 choroidal blood vessel http://purl.obolibrary.org/obo/UBERON_0003496 head blood vessel A blood vessel that is part of a choroid [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0002444 lens fiber http://purl.obolibrary.org/obo/UBERON_0034944 zone of organ A region of the lens consisting of packed elongated enucleate cells packed with crystallin. http://purl.obolibrary.org/obo/UBERON_0002450 decidua http://purl.obolibrary.org/obo/UBERON_0000478 extraembryonic structure The maternal uterine-derived portion of the placenta. http://purl.obolibrary.org/obo/GO_0016057 regulation of membrane potential in photoreceptor cell http://purl.obolibrary.org/obo/GO_0042391 regulation of membrane potential Hyperpolarization (vertebrates) or depolarization (invertebrates) of the photoreceptor cell membrane via closing/opening of cation specific channels as a result of signals generated by rhodopsin activation by a photon. http://purl.obolibrary.org/obo/UBERON_0002451 endometrial gland http://purl.obolibrary.org/obo/UBERON_0005398 female reproductive gland The mucous secreting gland associated with the mucuous membrane lining the uterus. http://purl.obolibrary.org/obo/UBERON_0002456 internal thoracic artery http://purl.obolibrary.org/obo/UBERON_0004573 systemic artery An artery that supplies the anterior chest wall and the breasts. It is a paired artery, with one running along each side of the sternum, to continue after its bifurcation as the superior epigastric and musculophrenic arteries. [WP,unvetted]. http://purl.obolibrary.org/obo/GO_0016079 synaptic vesicle exocytosis http://purl.obolibrary.org/obo/GO_0099003 vesicle-mediated transport in synapse Fusion of intracellular membrane-bounded vesicles with the pre-synaptic membrane of the neuronal cell resulting in release of neurotransmitter into the synaptic cleft. http://purl.obolibrary.org/obo/GO_0016109 tetraterpenoid biosynthetic process http://purl.obolibrary.org/obo/GO_0016114 terpenoid biosynthetic process The chemical reactions and pathways resulting in the formation of tetraterpenoid compounds, terpenoids with eight isoprene units. http://purl.obolibrary.org/obo/UBERON_0002457 intersomitic artery http://purl.obolibrary.org/obo/UBERON_0014907 intersomitic vessel The small branching sprouts of the dorsal aorta that grow across the medial surface of the somite, turn right angles to grow over that surface and then fuse with other sprouts and form the vertebral arteries adjacent to the neural tube; the intersomitic arteries supply the body wall and persist in the adult as the posterior intercostal, subcostal and the lumbar arteries. http://purl.obolibrary.org/obo/GO_0016110 tetraterpenoid catabolic process http://purl.obolibrary.org/obo/GO_0016115 terpenoid catabolic process The chemical reactions and pathways resulting in the breakdown of tetraterpenoid compounds, terpenoids with eight isoprene units. http://purl.obolibrary.org/obo/UBERON_0002458 spinal artery http://purl.obolibrary.org/obo/UBERON_0004573 systemic artery Arteries that supply the spinal cord. http://purl.obolibrary.org/obo/GO_0016114 terpenoid biosynthetic process http://purl.obolibrary.org/obo/GO_0008299 isoprenoid biosynthetic process The chemical reactions and pathways resulting in the formation of terpenoids, any member of a class of compounds characterized by an isoprenoid chemical structure. http://purl.obolibrary.org/obo/UBERON_0002460 vesical vein http://purl.obolibrary.org/obo/UBERON_0001638 vein A tributary of the iliac vein that drains the urinary bladder. http://purl.obolibrary.org/obo/GO_0016115 terpenoid catabolic process http://purl.obolibrary.org/obo/GO_0008300 isoprenoid catabolic process The chemical reactions and pathways resulting in the breakdown of terpenoids, any member of a class of compounds characterized by an isoprenoid chemical structure. http://purl.obolibrary.org/obo/UBERON_0002465 lymphoid system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system The lymphatic system in vertebrates is a network of conduits that carry a clear fluid called lymph. It also includes the lymphoid tissue through which the lymph travels. Lymphoid tissue is found in many organs, particularly the lymph nodes, and in the lymphoid follicles associated with the digestive system such as the tonsils. The system also includes all the structures dedicated to the circulation and production of lymphocytes, which includes the spleen, thymus, bone marrow and the lymphoid tissue associated with the digestive system[WP]. http://purl.obolibrary.org/obo/GO_0016116 carotenoid metabolic process http://purl.obolibrary.org/obo/GO_0006721 terpenoid metabolic process The chemical reactions and pathways involving carotenoids, tetraterpenoid compounds in which two units of 4 isoprenoid residues joined head-to-tail are themselves joined tail-to-tail. http://purl.obolibrary.org/obo/GO_0016117 carotenoid biosynthetic process http://purl.obolibrary.org/obo/GO_0016116 carotenoid metabolic process The chemical reactions and pathways resulting in the formation of carotenoids, tetraterpenoid compounds in which two units of 4 isoprenoid residues joined head-to-tail are themselves joined tail-to-tail. http://purl.obolibrary.org/obo/UBERON_0002466 intestine secretion http://purl.obolibrary.org/obo/UBERON_0000456 secretion of exocrine gland Clear to pale yellow watery secretions from the glands lining the small intestine walls. Secretion is stimulated by the mechanical pressure of partly digested food in the intestine. http://purl.obolibrary.org/obo/GO_0016118 carotenoid catabolic process http://purl.obolibrary.org/obo/GO_0016116 carotenoid metabolic process The chemical reactions and pathways resulting in the breakdown of carotenoids, tetraterpenoid compounds in which two units of 4 isoprenoid residues joined head-to-tail are themselves joined tail-to-tail. http://purl.obolibrary.org/obo/UBERON_0002469 esophagus mucosa http://purl.obolibrary.org/obo/UBERON_0000344 mucosa A mucosa that is part of a esophagus [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0016122 xanthophyll metabolic process http://purl.obolibrary.org/obo/GO_0016116 carotenoid metabolic process The chemical reactions and pathways involving xanthophylls, oxygen-containing carotenoids. http://purl.obolibrary.org/obo/GO_0016123 xanthophyll biosynthetic process http://purl.obolibrary.org/obo/GO_0016122 xanthophyll metabolic process The chemical reactions and pathways resulting in the formation of xanthophylls, oxygen-containing carotenoids. http://purl.obolibrary.org/obo/UBERON_0002470 autopod region http://purl.obolibrary.org/obo/UBERON_0002529 limb segment Terminal segment of free limb, immediately distal to the zeugopod region. The fully developed autopod consists of the autopod skeleton plus associated structures such as integument, muscle tissue, vasculature etc. The autopod is divided into mesopodial, metapodiual, and acropodial segments. Examples: human hand, mouse paw, human foot. http://purl.obolibrary.org/obo/GO_0016124 xanthophyll catabolic process http://purl.obolibrary.org/obo/GO_0016122 xanthophyll metabolic process The chemical reactions and pathways resulting in the breakdown of xanthophylls, oxygen-containing carotenoids. http://purl.obolibrary.org/obo/UBERON_0002471 zeugopod http://purl.obolibrary.org/obo/UBERON_0002529 limb segment The middle free limb segment, between the autopod and stylopod segments. Includes as parts the zeugopodial skeleton. Examples: There are two types of zeugopod: forelimb zeugopod (aka forearm), hindlimb zeugopod (aka crus). http://purl.obolibrary.org/obo/GO_0016202 regulation of striated muscle tissue development http://purl.obolibrary.org/obo/GO_1901861 regulation of muscle tissue development Any process that modulates the frequency, rate or extent of striated muscle development. http://purl.obolibrary.org/obo/UBERON_0002472 stylopod http://purl.obolibrary.org/obo/UBERON_0002529 limb segment The proximal free limb segment. Includes as parts the stylopod skeleton. http://purl.obolibrary.org/obo/GO_0016319 mushroom body development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the mushroom body over time, from its formation to the mature structure. The mushroom body is composed of the prominent neuropil structures of the insect central brain, thought to be crucial for olfactory associated learning. These consist mainly of a bulbous calyx and tightly packaged arrays of thin parallel fibers of the Kenyon cells. http://purl.obolibrary.org/obo/UBERON_0002473 intercerebral commissure http://purl.obolibrary.org/obo/UBERON_0019294 commissure of telencephalon A commissure that connects the two cerebral hemispheres. Examples: anterior commissure, corpus callosum. http://purl.obolibrary.org/obo/UBERON_0002474 cerebellar peduncular complex http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain A composite structure of the brain stem, which is subdivided into the superior cerebellar peduncle of pons, the decussation of superior cerebellar peduncle and the superior cerebellar peduncle of midbrain (MM)[NIF, based on NN]. http://purl.obolibrary.org/obo/GO_0016321 female meiosis chromosome segregation http://purl.obolibrary.org/obo/GO_0045132 meiotic chromosome segregation The cell cycle process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during the meiotic cell cycle in a female. http://purl.obolibrary.org/obo/GO_0016525 negative regulation of angiogenesis http://purl.obolibrary.org/obo/GO_2000181 negative regulation of blood vessel morphogenesis Any process that stops, prevents, or reduces the frequency, rate or extent of angiogenesis. http://purl.obolibrary.org/obo/UBERON_0002476 lateral globus pallidus http://purl.obolibrary.org/obo/UBERON_0005401 cerebral hemisphere gray matter The more lateral of the two segments of the globus pallidus, abutting the putamen. http://purl.obolibrary.org/obo/GO_0016528 sarcoplasm http://purl.obolibrary.org/obo/GO_0005737 cytoplasm The cytoplasm of a muscle cell; includes the sarcoplasmic reticulum. http://purl.obolibrary.org/obo/UBERON_0002477 medial globus pallidus http://purl.obolibrary.org/obo/UBERON_0005401 cerebral hemisphere gray matter The more medial segment of the globus pallidus. http://purl.obolibrary.org/obo/GO_0016594 glycine binding http://purl.obolibrary.org/obo/GO_0043169 cation binding Binding to glycine, aminoethanoic acid. http://purl.obolibrary.org/obo/UBERON_0002478 orbitosphenoid http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure The bone that is situated in the orbit on either side of the presphenoid; it generally forms a part of the sphenoid in the adult, and may be independent in the young. http://purl.obolibrary.org/obo/GO_0016597 amino acid binding http://purl.obolibrary.org/obo/GO_0005488 binding Binding to an amino acid, organic acids containing one or more amino substituents. http://purl.obolibrary.org/obo/UBERON_0002479 dorsal lateral geniculate nucleus http://purl.obolibrary.org/obo/UBERON_0015233 nucleus of dorsal thalamus The main division of the lateral geniculate body; consists of two magnocellular layers [TA] (strata magnocellularia [TA]) and four parvocellular layers [TA] (strata parvocellularia [TA]) and serves as a processing station in the major pathway from the retina to the cerebral cortex, receiving fibers from the optic tract and giving rise to the geniculocalcarine radiation to the visual cortex in the occipital lobe. http://purl.obolibrary.org/obo/GO_0016746 acyltransferase activity http://purl.obolibrary.org/obo/GO_0016740 transferase activity Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor). http://purl.obolibrary.org/obo/GO_0016817 hydrolase activity, acting on acid anhydrides http://purl.obolibrary.org/obo/GO_0016787 hydrolase activity Catalysis of the hydrolysis of any acid anhydride. http://purl.obolibrary.org/obo/UBERON_0002481 bone tissue http://purl.obolibrary.org/obo/UBERON_0004755 skeletal tissue Skeletal tissue with a collagen-rich extracellular matrix vascularized, mineralized with hydroxyapatite and typically including osteocytes located in lacunae that communicate with one another by cell processes (in canaliculi). Bone is deposited by osteoblasts. http://purl.obolibrary.org/obo/GO_0016922 nuclear receptor binding http://purl.obolibrary.org/obo/GO_0061629 RNA polymerase II-specific DNA-binding transcription factor binding Binding to a nuclear receptor protein. Nuclear receptor proteins are DNA-binding transcription factors which are regulated by binding to a ligand. http://purl.obolibrary.org/obo/GO_0017046 peptide hormone binding http://purl.obolibrary.org/obo/GO_0042562 hormone binding Binding to a peptide with hormonal activity in animals. http://purl.obolibrary.org/obo/UBERON_0002482 lamellar bone http://purl.obolibrary.org/obo/UBERON_0002481 bone tissue Bone tissue that has a regular parallel alignment of collagen into sheets (lamellae) and is mechanically strong. http://purl.obolibrary.org/obo/UBERON_0002484 bone marrow cavity http://purl.obolibrary.org/obo/UBERON_0002553 anatomical cavity The medullary cavities of the bones where bone marrow is stored. http://purl.obolibrary.org/obo/GO_0017126 nucleologenesis http://purl.obolibrary.org/obo/GO_0044085 cellular component biogenesis A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a nucleolus, a small, dense body one or more of which are present in the nucleus of eukaryotic cells. http://purl.obolibrary.org/obo/UBERON_0002485 prostate duct http://purl.obolibrary.org/obo/UBERON_0005904 duct of male reproductive system The minute canals that pass the prostatic secretions to the urethra. http://purl.obolibrary.org/obo/GO_0017145 stem cell division http://purl.obolibrary.org/obo/GO_0051301 cell division The self-renewing division of a stem cell. A stem cell is an undifferentiated cell, in the embryo or adult, that can undergo unlimited division and give rise to one or several different cell types. http://purl.obolibrary.org/obo/UBERON_0002490 frontal suture http://purl.obolibrary.org/obo/UBERON_0003685 cranial suture A suture that connects the two frontal bones of the skull. http://purl.obolibrary.org/obo/GO_0017156 calcium-ion regulated exocytosis http://purl.obolibrary.org/obo/GO_0045055 regulated exocytosis The release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle by fusion of the vesicle with the plasma membrane of a cell, induced by a rise in cytosolic calcium-ion levels. http://purl.obolibrary.org/obo/UBERON_0002497 acromion http://purl.obolibrary.org/obo/UBERON_0004530 bony projection Region of the scapula where the latter meets with the clavicle: attachment point of the clavicle to the scapula in some taxa. http://purl.obolibrary.org/obo/UBERON_0002498 deltopectoral crest http://purl.obolibrary.org/obo/UBERON_4100000 skeletal element projection A rough elevation at the middle of the lateral side of the shaft of the humerus to which the deltoid muscle attaches. http://purl.obolibrary.org/obo/GO_0017158 regulation of calcium ion-dependent exocytosis http://purl.obolibrary.org/obo/GO_1903305 regulation of regulated secretory pathway Any process that modulates the frequency, rate or extent of calcium ion-dependent exocytosis. http://purl.obolibrary.org/obo/GO_0019222 regulation of metabolic process http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism. http://purl.obolibrary.org/obo/UBERON_0002499 cochlear labyrinth http://purl.obolibrary.org/obo/UBERON_0000064 organ part The labyrinth is a system of fluid passages in the inner ear, including both the cochlea, which is part of the auditory system, and the vestibular system, which provides the sense of balance. It is named by analogy with the mythical maze that imprisoned the Minotaur, because of its appearance. The bony labyrinth, or osseous labyrinth, is the network of passages with bony walls lined with periosteum. The bony labyrinth is lined with the membranous labyrinth. There is a layer of perilymph between them. The three parts of the bony labyrinth are the vestibule of the ear, the semicircular canals, and the cochlea. The vestibular system is the region of the inner ear where the semicircular canals converge, close to the cochlea (the hearing organ). The vestibular system works with the visual system to keep objects in focus when the head is moving. Joint and muscle receptors also are important in maintaining balance. The brain receives, interprets, and processes the information from these systems that control our balance. [WP,unvetted]. http://purl.obolibrary.org/obo/GO_0019252 starch biosynthetic process http://purl.obolibrary.org/obo/GO_0009250 glucan biosynthetic process The chemical reactions and pathways resulting in the formation of starch, the most important reserve polysaccharide in plants. http://purl.obolibrary.org/obo/GO_0019750 chloroplast localization http://purl.obolibrary.org/obo/GO_0051644 plastid localization Any process in which a chloroplast is transported to, and/or maintained in, a specific location within the cell. A chloroplast is a chlorophyll-containing plastid found in cells of algae and higher plants. http://purl.obolibrary.org/obo/UBERON_0002506 iris epithelium http://purl.obolibrary.org/obo/UBERON_0015808 eye epithelium An epithelium that is part of a iris [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0019827 stem cell population maintenance http://purl.obolibrary.org/obo/GO_0098727 maintenance of cell number The process by which an organism or tissue maintains a population of stem cells of a single type. This can be achieved by a number of mechanisms: stem cell asymmetric division maintains stem cell numbers; stem cell symmetric division increases them; maintenance of a stem cell niche maintains the conditions for commitment to the stem cell fate for some types of stem cell; stem cells may arise de novo from other cell types. http://purl.obolibrary.org/obo/GO_0019867 outer membrane http://purl.obolibrary.org/obo/GO_0016020 membrane The external membrane of Gram-negative bacteria or certain organelles such as mitochondria and chloroplasts; freely permeable to most ions and metabolites. http://purl.obolibrary.org/obo/UBERON_0002507 abdominal lymph node http://purl.obolibrary.org/obo/UBERON_0005172 abdomen element A lymph node that is part of an abdomen [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0021782 glial cell development http://purl.obolibrary.org/obo/GO_0048468 cell development The process aimed at the progression of a glial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. http://purl.obolibrary.org/obo/GO_0022406 membrane docking http://purl.obolibrary.org/obo/GO_0009987 cellular process The initial attachment of a membrane or protein to a target membrane. Docking requires only that the proteins come close enough to interact and adhere. http://purl.obolibrary.org/obo/UBERON_0002509 mesenteric lymph node http://purl.obolibrary.org/obo/UBERON_0015860 visceral abdominal lymph node The lymph nodes located in the mesentery, of which there are 3 classes: ileocolic, juxtaintestinal mesenteric, and central superior group. http://purl.obolibrary.org/obo/GO_0022604 regulation of cell morphogenesis http://purl.obolibrary.org/obo/GO_0022603 regulation of anatomical structure morphogenesis Any process that modulates the frequency, rate or extent of cell morphogenesis. Cell morphogenesis is the developmental process in which the shape of a cell is generated and organized. http://purl.obolibrary.org/obo/UBERON_0002511 trabecula carnea http://purl.obolibrary.org/obo/UBERON_0000440 trabecula The supporting bundles of muscular fibers lining the walls of the ventricles of the heart. http://purl.obolibrary.org/obo/GO_0022617 extracellular matrix disassembly http://purl.obolibrary.org/obo/GO_0030198 extracellular matrix organization A process that results in the breakdown of the extracellular matrix. http://purl.obolibrary.org/obo/UBERON_0002512 corpus luteum http://purl.obolibrary.org/obo/UBERON_0005398 female reproductive gland A transient endocrine gland that develops from the postovulatory or atretic follicles and secretes progesterone; it is thought to be related to egg retention[PMID]. http://purl.obolibrary.org/obo/GO_0022803 passive transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity Enables the transfer of a single solute from one side of a membrane to the other by a mechanism involving conformational change, either by facilitated diffusion or in a membrane potential dependent process if the solute is charged. http://purl.obolibrary.org/obo/UBERON_0002513 endochondral bone http://purl.obolibrary.org/obo/UBERON_0010363 endochondral element Replacement bone that forms within cartilage. http://purl.obolibrary.org/obo/GO_0022804 active transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity Enables the transfer of a specific substance or related group of substances from one side of a membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction. http://purl.obolibrary.org/obo/UBERON_0002514 intramembranous bone http://purl.obolibrary.org/obo/UBERON_0001474 bone element Bone tissue forms directly within mesenchyme, and does not replace other tissues[TAO]. Intramembranous ossification is the formation of bone in which osteoblasts secrete a collagen-proteoglycan matrix that binds calcium salts and becomes calcified[GO]. Intramembranous ossification is the way flat bones and the shell of a turtle are formed[GO]. Unlike endochondral ossification, cartilage is not present during intramembranous ossification[WP]. http://purl.obolibrary.org/obo/GO_0022834 ligand-gated channel activity http://purl.obolibrary.org/obo/GO_0022836 gated channel activity Enables the transmembrane transfer of a solute by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts. http://purl.obolibrary.org/obo/UBERON_0002515 periosteum http://purl.obolibrary.org/obo/UBERON_0000158 membranous layer The thick fibrous membrane that closely invests the entire surface of a bone except the articular cartilage at synovial joints. http://purl.obolibrary.org/obo/GO_0022884 macromolecule transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity Enables the transfer of a macromolecule from one side of a membrane to the other. http://purl.obolibrary.org/obo/UBERON_0002517 basicranium http://purl.obolibrary.org/obo/UBERON_0000075 subdivision of skeletal system The base of skull is the most inferior area of the skull, composed of the endocranium and lower parts of the skull roof. http://purl.obolibrary.org/obo/GO_0030007 intracellular potassium ion homeostasis http://purl.obolibrary.org/obo/GO_0055075 potassium ion homeostasis A homeostatic process involved in the maintenance of a steady state level of potassium ions within a cell. http://purl.obolibrary.org/obo/UBERON_0002518 otolith organ http://purl.obolibrary.org/obo/UBERON_0006585 vestibular organ The crystalline particles composed of calcium carbonate and a protein which adhere to the gelatinous membrane of the maculae of the utricle and saccule (otolithic membrane). http://purl.obolibrary.org/obo/GO_0030166 proteoglycan biosynthetic process http://purl.obolibrary.org/obo/GO_0009101 glycoprotein biosynthetic process The chemical reactions and pathways resulting in the formation of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans. http://purl.obolibrary.org/obo/UBERON_0002521 elastic tissue http://purl.obolibrary.org/obo/UBERON_0002384 connective tissue Connective tissue composed of elastic fibers. http://purl.obolibrary.org/obo/GO_0030168 platelet activation http://purl.obolibrary.org/obo/GO_0001775 cell activation A series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. These events include shape change, adhesiveness, aggregation, and release reactions. When carried through to completion, these events lead to the formation of a stable hemostatic plug. http://purl.obolibrary.org/obo/UBERON_0002522 tunica media http://purl.obolibrary.org/obo/UBERON_0004797 blood vessel layer The middle layer of an artery or vein. [WP,unvetted]. http://purl.obolibrary.org/obo/UBERON_0002523 tunica intima http://purl.obolibrary.org/obo/UBERON_0004923 organ component layer The innermost layer of a blood vessel which is a lining of endothelial cells facing the lumen[Kardong]. http://purl.obolibrary.org/obo/GO_0030193 regulation of blood coagulation http://purl.obolibrary.org/obo/GO_1900046 regulation of hemostasis Any process that modulates the frequency, rate or extent of blood coagulation. http://purl.obolibrary.org/obo/UBERON_0002527 pancreatic lymph node http://purl.obolibrary.org/obo/UBERON_0002507 abdominal lymph node A lymph node that is part of a pancreas [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0030195 negative regulation of blood coagulation http://purl.obolibrary.org/obo/GO_0030193 regulation of blood coagulation Any process that stops, prevents, or reduces the frequency, rate or extent of blood coagulation. http://purl.obolibrary.org/obo/UBERON_0002528 sacral lymph node http://purl.obolibrary.org/obo/UBERON_0005179 pelvic region element A lymph node located in the sacral region. http://purl.obolibrary.org/obo/GO_0030198 extracellular matrix organization http://purl.obolibrary.org/obo/GO_0045229 external encapsulating structure organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix. http://purl.obolibrary.org/obo/UBERON_0002529 limb segment http://purl.obolibrary.org/obo/UBERON_0010538 paired limb/fin segment A major subdivision of a mature or developing limb, including both skeletal elements (or the mesenchyme that gives rise to the skeletal elements) and associated tissues, such as muscle, connective tissue, integument. Examples: autopod region, zeugopod region, stylopod region, metapodial region, arm region. Excludes the limb girdles. http://purl.obolibrary.org/obo/GO_0030225 macrophage differentiation http://purl.obolibrary.org/obo/GO_1903131 mononuclear cell differentiation The process in which a relatively unspecialized monocyte acquires the specialized features of a macrophage. http://purl.obolibrary.org/obo/GO_0030239 myofibril assembly http://purl.obolibrary.org/obo/GO_0140694 membraneless organelle assembly Formation of myofibrils, the repeating units of striated muscle. http://purl.obolibrary.org/obo/UBERON_0002530 gland http://purl.obolibrary.org/obo/UBERON_0000062 organ An organ that functions as a secretory or excretory organ. http://purl.obolibrary.org/obo/GO_0030397 membrane disassembly http://purl.obolibrary.org/obo/GO_0061024 membrane organization The controlled breakdown of any cell membrane in the context of a normal process such as autophagy. http://purl.obolibrary.org/obo/UBERON_0002532 epiblast (generic) http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure In amniote animal embryology, the epiblast is a tissue type derived either from the inner cell mass in mammals or the blastodisc in birds and reptiles. It lies above the hypoblast. In mammalian embryogenesis, the columnar cells of the epiblast are adjacent to the trophoblast, while the cuboidal cells of the hypoblast are closer to the blastocoele. The epiblast, whilst referred to as the primary ectoderm, differentiates to form all three layers of the trilaminar germ disc in a process called gastrulation[WP]. The outer of the two layers of the blastoderm that form during gastrulation, corresponding to primitive ectoderm during gastrulation and to the definitive ectoderm after gastrulation[ZFA]. http://purl.obolibrary.org/obo/GO_0030574 collagen catabolic process http://purl.obolibrary.org/obo/GO_0032963 collagen metabolic process The proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix, usually carried out by proteases secreted by nearby cells. http://purl.obolibrary.org/obo/GO_0030658 transport vesicle membrane http://purl.obolibrary.org/obo/GO_0030659 cytoplasmic vesicle membrane The lipid bilayer surrounding a transport vesicle. http://purl.obolibrary.org/obo/UBERON_0002533 post-anal tail bud http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure The rapidly proliferating mass of cells at the caudal extremity of the embryo; remnant of the primitive node. http://purl.obolibrary.org/obo/GO_0030660 Golgi-associated vesicle membrane http://purl.obolibrary.org/obo/GO_0030659 cytoplasmic vesicle membrane The lipid bilayer surrounding a vesicle associated with the Golgi apparatus. http://purl.obolibrary.org/obo/GO_0030662 coated vesicle membrane http://purl.obolibrary.org/obo/GO_0030659 cytoplasmic vesicle membrane The lipid bilayer surrounding a coated vesicle. http://purl.obolibrary.org/obo/UBERON_0002536 arthropod sensillum http://purl.obolibrary.org/obo/UBERON_0000020 sense organ Sense organ embedded in the integument and consisting of one or a cluster of sensory neurons and associated sensory structures, support cells and glial cells forming a single organised unit with a largely bona-fide boundary.[FBbt]. http://purl.obolibrary.org/obo/GO_0030665 clathrin-coated vesicle membrane http://purl.obolibrary.org/obo/GO_0030662 coated vesicle membrane The lipid bilayer surrounding a clathrin-coated vesicle. http://purl.obolibrary.org/obo/GO_0030705 cytoskeleton-dependent intracellular transport http://purl.obolibrary.org/obo/GO_0046907 intracellular transport The directed movement of substances along cytoskeletal fibers such as microfilaments or microtubules within a cell. http://purl.obolibrary.org/obo/UBERON_0002537 hermaphrodite gonad http://purl.obolibrary.org/obo/UBERON_0000991 gonad A gonad with both testicular and ovarian aspects[WP]. http://purl.obolibrary.org/obo/UBERON_0002539 pharyngeal arch http://purl.obolibrary.org/obo/UBERON_0010314 structure with developmental contribution from neural crest One of a series of paired bulges that develop along the lateral walls of the foregut. The pharyngeal arches have developmental contributions from endoderm, mesoderm, and neural crest cells and are separated by anterior lateral endoderm out-pockets known as pharyngeal pouches. http://purl.obolibrary.org/obo/GO_0030951 establishment or maintenance of microtubule cytoskeleton polarity http://purl.obolibrary.org/obo/GO_0030952 establishment or maintenance of cytoskeleton polarity Any cellular process that results in the specification, formation or maintenance of polarized microtubule-based cytoskeletal structures. http://purl.obolibrary.org/obo/GO_0031032 actomyosin structure organization http://purl.obolibrary.org/obo/GO_0030036 actin cytoskeleton organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures containing both actin and myosin or paramyosin. The myosin may be organized into filaments. http://purl.obolibrary.org/obo/UBERON_0002540 lateral line system http://purl.obolibrary.org/obo/UBERON_0001032 sensory system A line of sensory organs and associated structures along the sides of fish and amphibia that detect vibrations and pressure changes. http://purl.obolibrary.org/obo/UBERON_0002544 digit http://purl.obolibrary.org/obo/UBERON_0005881 autopodial extension A subdivision of the autopod that has as part a series of phalanges together with associated vasculature, musculature, integument and nerves. It is continuous with the metapodial subdivision of the autopod, but does not include the metapodials. In species such as humans, fully formed digits are distinct, whereas in other species the digits may be connected by interdigital webbing, or may be completely unseparated (for example, in cetaceans). http://purl.obolibrary.org/obo/GO_0031090 organelle membrane http://purl.obolibrary.org/obo/GO_0016020 membrane A membrane that is one of the two lipid bilayers of an organelle envelope or the outermost membrane of single membrane bound organelle. http://purl.obolibrary.org/obo/GO_0031113 regulation of microtubule polymerization http://purl.obolibrary.org/obo/GO_0031110 regulation of microtubule polymerization or depolymerization Any process that modulates the frequency, rate or extent of microtubule polymerization. http://purl.obolibrary.org/obo/UBERON_0002546 cranial placode http://purl.obolibrary.org/obo/UBERON_0005085 ectodermal placode Ectodermal placode that develops in the head into a part of the sensory nervous system. With a few exceptions (lens, adenohypophyseal), cranial placodes are neurogenic. http://purl.obolibrary.org/obo/GO_0031122 cytoplasmic microtubule organization http://purl.obolibrary.org/obo/GO_0000226 microtubule cytoskeleton organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins in the cytoplasm of a cell. http://purl.obolibrary.org/obo/UBERON_0002548 larva http://purl.obolibrary.org/obo/UBERON_0000468 multicellular organism A distinct juvenile form many animals undergo before metamorphosis into adults. Animals with indirect development such as insects, amphibians, or cnidarians typically have a larval phase of their life cycle. http://purl.obolibrary.org/obo/GO_0031344 regulation of cell projection organization http://purl.obolibrary.org/obo/GO_0051128 regulation of cellular component organization Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections. http://purl.obolibrary.org/obo/UBERON_0002553 anatomical cavity http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space Anatomical space which contains portions of one or more body substances and is bounded by the internal surface of one maximally connected anatomical structure. Examples: cranial cavity, pharyngeal recess space, nasal cavity, tooth socket, cavity of serous sac, lumen of stomach, lumen of artery, fornix of vagina. http://purl.obolibrary.org/obo/GO_0031346 positive regulation of cell projection organization http://purl.obolibrary.org/obo/GO_0051130 positive regulation of cellular component organization Any process that activates or increases the frequency, rate or extent of the process involved in the formation, arrangement of constituent parts, or disassembly of cell projections. http://purl.obolibrary.org/obo/GO_0031347 regulation of defense response http://purl.obolibrary.org/obo/GO_0080134 regulation of response to stress Any process that modulates the frequency, rate or extent of a defense response. http://purl.obolibrary.org/obo/UBERON_0002555 intermediate hypothalamic region http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain The portion of the hypothalamus located generally internal to the region of the infundibulum. http://purl.obolibrary.org/obo/GO_0031514 motile cilium http://purl.obolibrary.org/obo/GO_0005929 cilium A cilium which may have a variable arrangement of axonemal microtubules and also contains molecular motors. It may beat with a whip-like pattern that promotes cell motility or transport of fluids and other cells across a cell surface, such as on epithelial cells that line the lumenal ducts of various tissues; or they may display a distinct twirling motion that directs fluid flow asymmetrically across the cellular surface to affect asymmetric body plan organization. Motile cilia can be found in single as well as multiple copies per cell. http://purl.obolibrary.org/obo/UBERON_0002561 lumen of central nervous system http://purl.obolibrary.org/obo/UBERON_0002558 organ cavity The cavity that is enclosed by the central nervous system. In vertebrates this is the cavity that includes as parts ventricular cavities and the central canal of the spinal cord that develops from the lumen of the neura tube. http://purl.obolibrary.org/obo/UBERON_0002567 basal part of pons http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain Ventral subdivision of the pons which consists of the massive pontine pertuberance on pontine ventral surface. http://purl.obolibrary.org/obo/GO_0031969 chloroplast membrane http://purl.obolibrary.org/obo/GO_0042170 plastid membrane Either of the lipid bilayers that surround a chloroplast and form the chloroplast envelope. http://purl.obolibrary.org/obo/UBERON_0002596 ventral posterior nucleus of thalamus http://purl.obolibrary.org/obo/UBERON_0015233 nucleus of dorsal thalamus Part of thalamus receiving primary somatic sensory information via the medial lemniscal pathway that projects to the primary somatosensory cortex (adapted from Paxinos, The Rat Nervous System, 2nd Ed, Academic Press, 1995). http://purl.obolibrary.org/obo/UBERON_0002600 limbic lobe http://purl.obolibrary.org/obo/UBERON_0016526 lobe of cerebral hemisphere Part of cerebral hemisphere located on the medial surface, forming a ring around the brain stem. http://purl.obolibrary.org/obo/GO_0031982 vesicle http://purl.obolibrary.org/obo/GO_0043227 membrane-bounded organelle Any small, fluid-filled, spherical organelle enclosed by membrane. http://purl.obolibrary.org/obo/GO_0032056 positive regulation of translation in response to stress http://purl.obolibrary.org/obo/GO_0045727 positive regulation of translation Any process that activates or increases the frequency, rate or extent of translation as a result of a stimulus indicating the organism is under stress. http://purl.obolibrary.org/obo/UBERON_0002610 cochlear nuclear complex http://purl.obolibrary.org/obo/UBERON_0019263 gray matter of hindbrain The cochlear nuclei consist of: (a) the dorsal cochlear nucleus, corresponding to the tuberculum acusticum on the dorso-lateral surface of the inferior peduncle; and (b) the ventral or accessory cochlear nucleus, placed between the two divisions of the nerve, on the ventral aspect of the inferior peduncle. [WP,unvetted]. http://purl.obolibrary.org/obo/GO_0032102 negative regulation of response to external stimulus http://purl.obolibrary.org/obo/GO_0048585 negative regulation of response to stimulus Any process that stops, prevents, or reduces the frequency, rate or extent of a response to an external stimulus. http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain http://purl.obolibrary.org/obo/UBERON_0000073 regional part of nervous system Anatomical divisons of the brain according to one or more criteria, e.g. cytoarchitectural, gross anatomy. Parts may be contiguous in 3D or not, e.g., basal ganglia. http://purl.obolibrary.org/obo/GO_0032222 regulation of synaptic transmission, cholinergic http://purl.obolibrary.org/obo/GO_0050804 modulation of chemical synaptic transmission Any process that modulates the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine. http://purl.obolibrary.org/obo/UBERON_0002622 preoptic periventricular nucleus http://purl.obolibrary.org/obo/UBERON_0007251 preoptic nucleus The preoptic periventricular nucleus is located along the midline and is medial to the medial preoptic nucleus.[WP,unvetted]. http://purl.obolibrary.org/obo/GO_0032223 negative regulation of synaptic transmission, cholinergic http://purl.obolibrary.org/obo/GO_0032222 regulation of synaptic transmission, cholinergic Any process that stops, prevents, or reduces the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine. http://purl.obolibrary.org/obo/UBERON_0002625 median preoptic nucleus http://purl.obolibrary.org/obo/UBERON_0007251 preoptic nucleus The median preoptic nucleus is located along the midline in a position significantly dorsal to the other 3 preoptic nuclei, at least in the macaca fascicularis brain. It wraps around the top (dorsal), front, and bottom (ventral) surfaces of the anterior commissure. The median preoptic nucleus generates thirst. Drinking decreases noradrenaline release in the median preoptic nucleus. http://purl.obolibrary.org/obo/GO_0032224 positive regulation of synaptic transmission, cholinergic http://purl.obolibrary.org/obo/GO_0032222 regulation of synaptic transmission, cholinergic Any process that activates, maintains or increases the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine. http://purl.obolibrary.org/obo/UBERON_0002639 midbrain reticular formation http://purl.obolibrary.org/obo/UBERON_0019267 gray matter of midbrain Part of the reticular formation located in the midbrain tegmentum. http://purl.obolibrary.org/obo/GO_0032413 negative regulation of ion transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0034766 negative regulation of monoatomic ion transmembrane transport Any process that stops or reduces the activity of an ion transporter. http://purl.obolibrary.org/obo/UBERON_0002663 septal nuclear complex http://purl.obolibrary.org/obo/UBERON_0007245 nuclear complex of neuraxis Collection of nerve cells in the medial forebrain lying generally in front of the anterior commissure (Maryann Martone). http://purl.obolibrary.org/obo/GO_0032535 regulation of cellular component size http://purl.obolibrary.org/obo/GO_0090066 regulation of anatomical structure size A process that modulates the size of a cellular component. http://purl.obolibrary.org/obo/UBERON_0002667 lateral septal nucleus http://purl.obolibrary.org/obo/UBERON_0009663 telencephalic nucleus Regional part of the septal nuclei, lying dorsal and slightly lateral to the medial septal nucleus. The lateral septum receives the bulk of projections of areas projecting to the septal nuclei (Adapted from Brodal, 1981). http://purl.obolibrary.org/obo/GO_0032553 ribonucleotide binding http://purl.obolibrary.org/obo/GO_0097367 carbohydrate derivative binding Binding to a ribonucleotide, any compound consisting of a ribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety. http://purl.obolibrary.org/obo/UBERON_0002668 oculomotor nerve root http://purl.obolibrary.org/obo/UBERON_0006843 root of cranial nerve Initial segment of the occulomotor nerve as it leaves the midbrain. http://purl.obolibrary.org/obo/GO_0032782 bile acid secretion http://purl.obolibrary.org/obo/GO_0046717 acid secretion The regulated release of bile acid, composed of any of a group of steroid carboxylic acids occurring in bile, by a cell or a tissue. http://purl.obolibrary.org/obo/UBERON_0002673 vestibular nuclear complex http://purl.obolibrary.org/obo/UBERON_0019263 gray matter of hindbrain Nuclear complex containing the vestibular nuclei. http://purl.obolibrary.org/obo/GO_0032869 cellular response to insulin stimulus http://purl.obolibrary.org/obo/GO_0071375 cellular response to peptide hormone stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms. http://purl.obolibrary.org/obo/UBERON_0002689 supraoptic crest http://purl.obolibrary.org/obo/UBERON_0010135 sensory circumventricular organ One of the circumventricular organs of the brain. The OVLT is outside the blood brain barrier, and so neurons in this region can respond to factors that are present in the systemic circulation. http://purl.obolibrary.org/obo/GO_0032870 cellular response to hormone stimulus http://purl.obolibrary.org/obo/GO_0009725 response to hormone Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus. http://purl.obolibrary.org/obo/UBERON_0002691 ventral tegmental area http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain Unpaired midbrain region situated in the ventromedial portion of the reticular formation. The VTA is medial to the substantia nigra and ventral to the red nucleus, and extends caudally from the posterior hypothalamus in the diencephalon. The VTA contains dopamine neurons that project to various limbic and cortical areas and is a critical component of the brain's reward circuitry. http://purl.obolibrary.org/obo/GO_0032879 regulation of localization http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process Any process that modulates the frequency, rate or extent of any process in which a cell, a substance, or a cellular entity is transported to, or maintained in, a specific location. http://purl.obolibrary.org/obo/UBERON_0002704 metathalamus http://purl.obolibrary.org/obo/UBERON_0015233 nucleus of dorsal thalamus The metathalamus is a composite structure of the thalamus, consisting of the medial geniculate nucleus and the lateral geniculate nucleus. [WP,unvetted]. http://purl.obolibrary.org/obo/GO_0032885 regulation of polysaccharide biosynthetic process http://purl.obolibrary.org/obo/GO_0032881 regulation of polysaccharide metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of polysaccharides. http://purl.obolibrary.org/obo/UBERON_0002707 corticospinal tract http://purl.obolibrary.org/obo/UBERON_0001018 axon tract The corticospinal fibers that arise from the pyramidal cells within the cerebral cortex layer V of the precentral motor area, the premotor area and the postcentral gyrus, then descend into and through the medulla to form the lateral corticospinal tract and the anterior corticospinal tract. http://purl.obolibrary.org/obo/GO_0032963 collagen metabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process The chemical reactions and pathways involving collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%). http://purl.obolibrary.org/obo/GO_0033002 muscle cell proliferation http://purl.obolibrary.org/obo/GO_0008283 cell population proliferation The expansion of a muscle cell population by cell division. http://purl.obolibrary.org/obo/UBERON_0002709 posterior nuclear complex of thalamus http://purl.obolibrary.org/obo/UBERON_0019269 gray matter of diencephalon Part of thalamus comprising ill defined cellular groups in the caudal thalamus at the meso-diencephalic junction. It is not a homogeneous structure but consists of several distinct cellular groups, including the suprageniculate and limitans nuclei, the magnocellular division of the medial geniculate body, portions of the pulvinar nucleus and an area of mixed cell types intercalated between the ventroposterior nucleus and the nucleus lateral posterior (Brodal, Neurological Anatomy, 3rd ed., 1981, pg 97). http://purl.obolibrary.org/obo/GO_0033047 regulation of mitotic sister chromatid segregation http://purl.obolibrary.org/obo/GO_0033045 regulation of sister chromatid segregation Any process that modulates the frequency, rate or extent of sister chromatid segregation during mitosis. http://purl.obolibrary.org/obo/UBERON_0002714 rubrospinal tract http://purl.obolibrary.org/obo/UBERON_0007702 tract of brain White matter tract arising in red nucleus and projecting to spinal cord ventral horn. http://purl.obolibrary.org/obo/GO_0033604 negative regulation of catecholamine secretion http://purl.obolibrary.org/obo/GO_0051953 negative regulation of amine transport Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a catecholamine. http://purl.obolibrary.org/obo/UBERON_0002726 cervical spinal cord http://purl.obolibrary.org/obo/UBERON_0005844 spinal cord segment A spinal cord segment that adjacent_to a cervical region. http://purl.obolibrary.org/obo/GO_0033605 positive regulation of catecholamine secretion http://purl.obolibrary.org/obo/GO_0051954 positive regulation of amine transport Any process that activates or increases the frequency, rate or extent of the regulated release of a catecholamine. http://purl.obolibrary.org/obo/UBERON_0002731 vestibulocochlear nerve root http://purl.obolibrary.org/obo/UBERON_0006843 root of cranial nerve Either of the two roots that come of the vestibulocochlear nerve. http://purl.obolibrary.org/obo/GO_0033993 response to lipid http://purl.obolibrary.org/obo/GO_0042221 response to chemical Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid stimulus. http://purl.obolibrary.org/obo/UBERON_0002736 lateral nuclear group of thalamus http://purl.obolibrary.org/obo/UBERON_0015233 nucleus of dorsal thalamus The lateral nuclear group is a collection of nuclei on the lateral side of the thalamus. According to MeSH, it consists of the following: lateral dorsal nucleus lateral posterior nucleus pulvinar [WP,unvetted]. http://purl.obolibrary.org/obo/GO_0034219 carbohydrate transmembrane transport http://purl.obolibrary.org/obo/GO_0055085 transmembrane transport The process in which a carbohydrate is transported across a membrane. http://purl.obolibrary.org/obo/UBERON_0002743 basal forebrain http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain A region of the brain consisting of ventral and rostral subcortical regions of the telencephalon, including among others, the basal ganglia, septal nuclei, amygdala, ventral pallidum, substantia innominata, and basal nucleus of Meynert. http://purl.obolibrary.org/obo/UBERON_0002749 regional part of cerebellar cortex http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain A regional part of brain that is part of a cerebellar cortex [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0002770 posterior hypothalamic region http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain The part of the hypothalamus posterior to the middle region consisting of several nuclei including the medial mamillary nucleus, lateral mamillary nucleus, and posterior hypothalamic nucleus (posterior hypothalamic area). The posterior hypothalamic area is concerned with control of sympathetic responses and is sensitive to conditions of decreasing temperature and controls the mechanisms for the conservation and increased production of heat. http://purl.obolibrary.org/obo/GO_0034220 monoatomic ion transmembrane transport http://purl.obolibrary.org/obo/GO_0055085 transmembrane transport A process in which a monoatomic ion is transported across a membrane. Monatomic ions (also called simple ions) are ions consisting of exactly one atom. http://purl.obolibrary.org/obo/GO_0034284 response to monosaccharide http://purl.obolibrary.org/obo/GO_0009743 response to carbohydrate Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monosaccharide stimulus. http://purl.obolibrary.org/obo/UBERON_0002776 ventral nuclear group http://purl.obolibrary.org/obo/UBERON_0015233 nucleus of dorsal thalamus Nuclei in the ventral part of the thalamus, involved in modulating activity of dorsal thalamic nuclei. http://purl.obolibrary.org/obo/GO_0034654 nucleobase-containing compound biosynthetic process http://purl.obolibrary.org/obo/GO_0009058 biosynthetic process The chemical reactions and pathways resulting in the formation of nucleobases, nucleosides, nucleotides and nucleic acids. http://purl.obolibrary.org/obo/GO_0034703 cation channel complex http://purl.obolibrary.org/obo/GO_0034702 monoatomic ion channel complex An ion channel complex through which cations pass. http://purl.obolibrary.org/obo/UBERON_0002802 left parietal lobe http://purl.obolibrary.org/obo/UBERON_0001872 parietal lobe Parietal lobe of the left hemisphere of the brain. http://purl.obolibrary.org/obo/GO_0035435 phosphate ion transmembrane transport http://purl.obolibrary.org/obo/GO_0055085 transmembrane transport The process in which a phosphate is transported across a membrane. http://purl.obolibrary.org/obo/GO_0035914 skeletal muscle cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a skeletal muscle cell, a somatic cell located in skeletal muscle. http://purl.obolibrary.org/obo/UBERON_0002803 right parietal lobe http://purl.obolibrary.org/obo/UBERON_0001872 parietal lobe Parietal lobe of the right hemisphere of the brain. http://purl.obolibrary.org/obo/GO_0035927 RNA import into mitochondrion http://purl.obolibrary.org/obo/GO_0055085 transmembrane transport The process in which a rRNA, ribosomal ribonucleic acid, is transported from the cytosol into the mitochondrial matrix. http://purl.obolibrary.org/obo/GO_0038187 pattern recognition receptor activity http://purl.obolibrary.org/obo/GO_0038023 signaling receptor activity Combining with a pathogen-associated molecular pattern (PAMP), a structure conserved among microbial species to initiate an innate immune response. http://purl.obolibrary.org/obo/UBERON_0002804 left limbic lobe http://purl.obolibrary.org/obo/UBERON_0002600 limbic lobe A limbic lobe that is part of a left cerebral hemisphere. http://purl.obolibrary.org/obo/GO_0042048 olfactory behavior http://purl.obolibrary.org/obo/GO_0007635 chemosensory behavior The behavior of an organism in response to an odor. http://purl.obolibrary.org/obo/GO_0042063 gliogenesis http://purl.obolibrary.org/obo/GO_0022008 neurogenesis The process that results in the generation of glial cells. This includes the production of glial progenitors and their differentiation into mature glia. http://purl.obolibrary.org/obo/UBERON_0002805 right limbic lobe http://purl.obolibrary.org/obo/UBERON_0002600 limbic lobe A limbic lobe that is part of a right cerebral hemisphere. http://purl.obolibrary.org/obo/GO_0042166 acetylcholine binding http://purl.obolibrary.org/obo/GO_0043169 cation binding Binding to acetylcholine, an acetic acid ester of the organic base choline that functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions. http://purl.obolibrary.org/obo/GO_0042170 plastid membrane http://purl.obolibrary.org/obo/GO_0031090 organelle membrane Either of the lipid bilayers that surround a plastid and form the plastid envelope. http://purl.obolibrary.org/obo/UBERON_0002808 left temporal lobe http://purl.obolibrary.org/obo/UBERON_0001871 temporal lobe A temporal lobe that is part of a left cerebral hemisphere. http://purl.obolibrary.org/obo/GO_0042435 indole-containing compound biosynthetic process http://purl.obolibrary.org/obo/GO_0009058 biosynthetic process The chemical reactions and pathways resulting in the formation of compounds that contain an indole (2,3-benzopyrrole) skeleton. http://purl.obolibrary.org/obo/GO_0042445 hormone metabolic process http://purl.obolibrary.org/obo/GO_0010817 regulation of hormone levels The chemical reactions and pathways involving any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone. http://purl.obolibrary.org/obo/UBERON_0002809 right temporal lobe http://purl.obolibrary.org/obo/UBERON_0001871 temporal lobe A temporal lobe that is part of a right cerebral hemisphere. http://purl.obolibrary.org/obo/GO_0042491 inner ear auditory receptor cell differentiation http://purl.obolibrary.org/obo/GO_0060113 inner ear receptor cell differentiation The process in which a relatively unspecialized inner cell acquires specialized features of an auditory hair cell. http://purl.obolibrary.org/obo/GO_0042551 neuron maturation http://purl.obolibrary.org/obo/GO_0048469 cell maturation A developmental process, independent of morphogenetic (shape) change, that is required for a neuron to attain its fully functional state. http://purl.obolibrary.org/obo/UBERON_0002810 right frontal lobe http://purl.obolibrary.org/obo/UBERON_0001870 frontal cortex A frontal cortex that is part of a right cerebral hemisphere. http://purl.obolibrary.org/obo/GO_0042646 plastid nucleoid http://purl.obolibrary.org/obo/GO_0009295 nucleoid The region of a plastid to which the DNA is confined. http://purl.obolibrary.org/obo/GO_0042742 defense response to bacterium http://purl.obolibrary.org/obo/GO_0009617 response to bacterium Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism. http://purl.obolibrary.org/obo/UBERON_0002811 left frontal lobe http://purl.obolibrary.org/obo/UBERON_0001870 frontal cortex A frontal cortex that is part of a left cerebral hemisphere. http://purl.obolibrary.org/obo/GO_0042762 regulation of sulfur metabolic process http://purl.obolibrary.org/obo/GO_0019222 regulation of metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving sulfur, the nonmetallic element sulfur or compounds that contain sulfur. http://purl.obolibrary.org/obo/GO_0042923 neuropeptide binding http://purl.obolibrary.org/obo/GO_0042277 peptide binding Interacting selectively and non-covalently and stoichiometrically with neuropeptides, peptides with direct synaptic effects (peptide neurotransmitters) or indirect modulatory effects on the nervous system (peptide neuromodulators). http://purl.obolibrary.org/obo/UBERON_0002812 left cerebral hemisphere http://purl.obolibrary.org/obo/UBERON_0001869 cerebral hemisphere A cerebral hemisphere that is in the left side of a brain. http://purl.obolibrary.org/obo/GO_0043065 positive regulation of apoptotic process http://purl.obolibrary.org/obo/GO_0043068 positive regulation of programmed cell death Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process. http://purl.obolibrary.org/obo/GO_0043067 regulation of programmed cell death http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes. http://purl.obolibrary.org/obo/UBERON_0002813 right cerebral hemisphere http://purl.obolibrary.org/obo/UBERON_0001869 cerebral hemisphere A cerebral hemisphere that is in the right side of a brain. http://purl.obolibrary.org/obo/GO_0043068 positive regulation of programmed cell death http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes. http://purl.obolibrary.org/obo/GO_0043169 cation binding http://purl.obolibrary.org/obo/GO_0043167 ion binding Binding to a cation, a charged atom or group of atoms with a net positive charge. http://purl.obolibrary.org/obo/UBERON_0002824 vestibular ganglion http://purl.obolibrary.org/obo/UBERON_0001800 sensory ganglion The ganglion of the vestibular nerve. It contains the cell bodies of the bipolar primary afferent neurons whose peripheral processes form synaptic contact with hair cells of the vestibular sensory end organs[WP,unvetted]. Distributed to the maculae of the utricle and saccule and to the ampullary crests of the semicircular ducts. The vestibular fibers arise in bipolar cells in the vestibular ganglion in the internal acoustic meatus. http://purl.obolibrary.org/obo/GO_0043200 response to amino acid http://purl.obolibrary.org/obo/GO_0001101 response to acid chemical Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups. http://purl.obolibrary.org/obo/GO_0043228 membraneless organelle http://purl.obolibrary.org/obo/GO_0043226 organelle Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane. Includes ribosomes, the cytoskeleton and chromosomes. http://purl.obolibrary.org/obo/UBERON_0002827 vestibulocochlear ganglion http://purl.obolibrary.org/obo/UBERON_0010313 neural crest-derived structure The group of neuron cell bodies associated with the eighth cranial nerve during embryogenesis; splits in later development to form the cochlear and vestibular ganglia. http://purl.obolibrary.org/obo/GO_0043269 regulation of monoatomic ion transport http://purl.obolibrary.org/obo/GO_0051049 regulation of transport Any process that modulates the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0043270 positive regulation of monoatomic ion transport http://purl.obolibrary.org/obo/GO_0051050 positive regulation of transport Any process that activates or increases the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/UBERON_0002828 ventral cochlear nucleus http://purl.obolibrary.org/obo/UBERON_0001720 cochlear nucleus The ventral cochlear nucleus (or anterior, or accessory), placed between the two divisions of the cochlear nerve, is on the ventral aspect of the inferior peduncle. Composed of several regions of distinct cell types, this nucleus serves primarily as a relay station for ascending auditory information. Bushy cells in the anterior ventral cochlear nucleus (AVCN), which receive end bulbs of held from auditory nerve fibers, project to the superior olivary complex through the trapezoid body and intermediate acoustic stria. Other cell types project to the lateral lemniscus and the inferior colliculus directly. [WP,unvetted]. http://purl.obolibrary.org/obo/GO_0043271 negative regulation of monoatomic ion transport http://purl.obolibrary.org/obo/GO_0051051 negative regulation of transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0043403 skeletal muscle tissue regeneration http://purl.obolibrary.org/obo/GO_0042246 tissue regeneration The regrowth of skeletal muscle tissue to repair injured or damaged muscle fibers in the postnatal stage. http://purl.obolibrary.org/obo/UBERON_0002829 dorsal cochlear nucleus http://purl.obolibrary.org/obo/UBERON_0001720 cochlear nucleus The dorsal cochlear nucleus (DCN, also known as the 'tuberculum acousticum'), is a cortex-like structure on the dorso-lateral surface of the brainstem. Along with the ventral cochlear nucleus, it forms the cochlear nucleus, where all auditory nerve fibers from the cochlea form their first synapses. [WP,unvetted]. http://purl.obolibrary.org/obo/GO_0043415 positive regulation of skeletal muscle tissue regeneration http://purl.obolibrary.org/obo/GO_0043416 regulation of skeletal muscle tissue regeneration Any process that activates or increase the rate of skeletal muscle regeneration. http://purl.obolibrary.org/obo/GO_0043416 regulation of skeletal muscle tissue regeneration http://purl.obolibrary.org/obo/GO_0048638 regulation of developmental growth Any process that modulates the frequency, rate or extent of skeletal muscle. http://purl.obolibrary.org/obo/GO_0043462 regulation of ATP-dependent activity http://purl.obolibrary.org/obo/GO_0065009 regulation of molecular function Any process that modulates the rate of an ATP-dependent activity. http://purl.obolibrary.org/obo/UBERON_0002835 thoracic dorsal root ganglion http://purl.obolibrary.org/obo/UBERON_0000044 dorsal root ganglion A dorsal root ganglion that is part of a thorax [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0043501 skeletal muscle adaptation http://purl.obolibrary.org/obo/GO_0014888 striated muscle adaptation Any process in which skeletal muscles change their phenotypic profiles in response to altered functional demands and a variety of signals. http://purl.obolibrary.org/obo/GO_0043502 regulation of muscle adaptation http://purl.obolibrary.org/obo/GO_0048583 regulation of response to stimulus Any process that modulates the frequency, rate or extent of muscle adaptation. http://purl.obolibrary.org/obo/UBERON_0002836 lumbar dorsal root ganglion http://purl.obolibrary.org/obo/UBERON_0000044 dorsal root ganglion The group of nerve cell bodies located on the dorsal spinal roots within the vertebral column at the level of the lumbar vertebrae. http://purl.obolibrary.org/obo/GO_0043542 endothelial cell migration http://purl.obolibrary.org/obo/GO_0016477 cell migration The orderly movement of an endothelial cell into the extracellular matrix to form an endothelium. http://purl.obolibrary.org/obo/GO_0043558 regulation of translational initiation in response to stress http://purl.obolibrary.org/obo/GO_0043555 regulation of translation in response to stress Any process that modulates the frequency, rate or extent of translation initiation, as a result of a stimulus indicating the organism is under stress. http://purl.obolibrary.org/obo/UBERON_0002871 hypoglossal nucleus http://purl.obolibrary.org/obo/UBERON_0007635 nucleus of medulla oblongata Nucleus forming a longitudinal cell column in the medulla, close beneath the floor of the 4th ventricle, containing motor neurons that innervate the muscles of the tongue (Brodal, Neurological Anatomy, 3rd ed., 1981, pg 453). http://purl.obolibrary.org/obo/GO_0043572 plastid fission http://purl.obolibrary.org/obo/GO_0048285 organelle fission The creation of two or more plastids by division of one plastid. A plastid is any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. http://purl.obolibrary.org/obo/GO_0043616 keratinocyte proliferation http://purl.obolibrary.org/obo/GO_0050673 epithelial cell proliferation The multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population. Keratinocytes are epidermal cells which synthesize keratin and undergo a characteristic change as they move upward from the basal layers of the epidermis to the cornified (horny) layer of the skin. http://purl.obolibrary.org/obo/UBERON_0002886 lateral amygdaloid nucleus http://purl.obolibrary.org/obo/UBERON_0009663 telencephalic nucleus The sensory interface of the amygdala where plasticity is mediated (Phelps & LeDoux, 2005, http://www.ncbi.nlm.nih.gov/pubmed/ 16242399). http://purl.obolibrary.org/obo/GO_0044085 cellular component biogenesis http://purl.obolibrary.org/obo/GO_0071840 cellular component organization or biogenesis A process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component. Includes biosynthesis of constituent macromolecules, and those macromolecular modifications that are involved in synthesis or assembly of the cellular component. http://purl.obolibrary.org/obo/GO_0044089 positive regulation of cellular component biogenesis http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the frequency, rate or extent of cellular component biogenesis, a process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component. http://purl.obolibrary.org/obo/UBERON_0002894 olfactory cortex http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain Aggregate brain region defined as those areas of cerebral cortex receiving direct synaptic input from the olfactory bulb (Price, 1973). It usually includes the piriform cortex and sometimes other areas. http://purl.obolibrary.org/obo/GO_0044091 membrane biogenesis http://purl.obolibrary.org/obo/GO_0044085 cellular component biogenesis A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a membrane. http://purl.obolibrary.org/obo/GO_0044419 biological process involved in interspecies interaction between organisms http://purl.obolibrary.org/obo/GO_0008150 biological_process Any process evolved to enable an interaction with an organism of a different species. http://purl.obolibrary.org/obo/UBERON_0002916 central sulcus http://purl.obolibrary.org/obo/UBERON_0013118 sulcus of brain The central sulcus is a fold in the cerebral cortex of brains in vertebrates. Also called the central fissure, it was originally called the fissure of Rolando or the Rolandic fissure, after Luigi Rolando. The central sulcus is a prominent landmark of the brain, separating the parietal lobe from the frontal lobe and the primary motor cortex from the primary somatosensory cortex. [WP,unvetted]. http://purl.obolibrary.org/obo/GO_0044743 protein transmembrane import into intracellular organelle http://purl.obolibrary.org/obo/GO_0033365 protein localization to organelle The directed movement of proteins into an intracellular organelle, across a membrane. http://purl.obolibrary.org/obo/GO_0045117 azole transmembrane transport http://purl.obolibrary.org/obo/GO_0071705 nitrogen compound transport The directed movement of azoles, heterocyclic compounds found in many biologically important substances, across a lipid bilayer, across a membrane. http://purl.obolibrary.org/obo/UBERON_0002921 longitudinal fissure http://purl.obolibrary.org/obo/UBERON_0014466 subarachnoid fissure The deep groove which separates the two hemispheres of the vertebrate brain. The falx cerebri, a dural brain covering, lies within the medial longitudinal fissure. [WP,unvetted]. http://purl.obolibrary.org/obo/GO_0045137 development of primary sexual characteristics http://purl.obolibrary.org/obo/GO_0003006 developmental process involved in reproduction The process whose specific outcome is the progression of the primary sexual characteristics over time, from their formation to the mature structures. The primary sexual characteristics are the testes in males and the ovaries in females and they develop in response to sex hormone secretion. http://purl.obolibrary.org/obo/GO_0045177 apical part of cell http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure The region of a polarized cell that forms a tip or is distal to a base. For example, in a polarized epithelial cell, the apical region has an exposed surface and lies opposite to the basal lamina that separates the epithelium from other tissue. http://purl.obolibrary.org/obo/UBERON_0002925 trigeminal nucleus http://purl.obolibrary.org/obo/UBERON_0000126 cranial nerve nucleus A nucleus of brain that is part of a trigeminal nuclear complex. http://purl.obolibrary.org/obo/GO_0045184 establishment of protein localization http://purl.obolibrary.org/obo/GO_0051234 establishment of localization The directed movement of a protein to a specific location. http://purl.obolibrary.org/obo/GO_0045229 external encapsulating structure organization http://purl.obolibrary.org/obo/GO_0016043 cellular component organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of external structures that lie outside the plasma membrane and surround the entire cell. http://purl.obolibrary.org/obo/UBERON_0002926 gustatory epithelium http://purl.obolibrary.org/obo/UBERON_0006934 sensory epithelium A sensory epithelium that is part of a gustatory system. http://purl.obolibrary.org/obo/GO_0045445 myoblast differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into striated muscle fibers. http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of cell differentiation, the process in which relatively unspecialized cells acquire specialized structural and functional features. http://purl.obolibrary.org/obo/UBERON_0002928 dentate gyrus polymorphic layer http://purl.obolibrary.org/obo/UBERON_0002304 layer of dentate gyrus A cellular layer of the dentate gyrus enclosed by the granule cell layer. A number of cell types are located in the polymorphic layer but the most prominent is the mossy cell. http://purl.obolibrary.org/obo/GO_0045597 positive regulation of cell differentiation http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the frequency, rate or extent of cell differentiation. http://purl.obolibrary.org/obo/GO_0045608 negative regulation of inner ear auditory receptor cell differentiation http://purl.obolibrary.org/obo/GO_2000981 negative regulation of inner ear receptor cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of auditory hair cell differentiation. http://purl.obolibrary.org/obo/UBERON_0002945 ventral posteromedial nucleus of thalamus http://purl.obolibrary.org/obo/UBERON_0015233 nucleus of dorsal thalamus The ventral posteromedial nucleus is a nucleus of the thalamus. [WP,unvetted]. http://purl.obolibrary.org/obo/UBERON_0002956 granular layer of cerebellar cortex http://purl.obolibrary.org/obo/UBERON_0004130 cerebellar layer The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer. http://purl.obolibrary.org/obo/GO_0045646 regulation of erythrocyte differentiation http://purl.obolibrary.org/obo/GO_0045637 regulation of myeloid cell differentiation Any process that modulates the frequency, rate or extent of erythrocyte differentiation. http://purl.obolibrary.org/obo/GO_0045649 regulation of macrophage differentiation http://purl.obolibrary.org/obo/GO_0002761 regulation of myeloid leukocyte differentiation Any process that modulates the frequency, rate or extent of macrophage differentiation. http://purl.obolibrary.org/obo/UBERON_0002961 archicortex http://purl.obolibrary.org/obo/UBERON_0014734 allocortex A portion of the cerebral cortex that, with the paleocortex, develops in association with the olfactory system, and which is phylogenetically older than the neocortex and lacks its layered structure. The embryonic archicortex corresponds to the cortex of the dentate gyrus and hippocampus in mature mammals. Being part of the limbic system, it has functions related to emotions and formation of memory. Signals being sent from the limbic lobe to the hippocampal formations can go via the archicortex as an intermediate. http://purl.obolibrary.org/obo/GO_0045650 negative regulation of macrophage differentiation http://purl.obolibrary.org/obo/GO_0045649 regulation of macrophage differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage differentiation. http://purl.obolibrary.org/obo/GO_0045651 positive regulation of macrophage differentiation http://purl.obolibrary.org/obo/GO_0045649 regulation of macrophage differentiation Any process that activates or increases the frequency, rate or extent of macrophage differentiation. http://purl.obolibrary.org/obo/UBERON_0002974 molecular layer of cerebellar cortex http://purl.obolibrary.org/obo/UBERON_0004130 cerebellar layer The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells. http://purl.obolibrary.org/obo/GO_0045664 regulation of neuron differentiation http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the frequency, rate or extent of neuron differentiation. http://purl.obolibrary.org/obo/GO_0045665 negative regulation of neuron differentiation http://purl.obolibrary.org/obo/GO_0045664 regulation of neuron differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of neuron differentiation. http://purl.obolibrary.org/obo/UBERON_0002979 Purkinje cell layer of cerebellar cortex http://purl.obolibrary.org/obo/UBERON_0004130 cerebellar layer The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells. http://purl.obolibrary.org/obo/GO_0045666 positive regulation of neuron differentiation http://purl.obolibrary.org/obo/GO_0045664 regulation of neuron differentiation Any process that activates or increases the frequency, rate or extent of neuron differentiation. http://purl.obolibrary.org/obo/GO_0045685 regulation of glial cell differentiation http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the frequency, rate or extent of glia cell differentiation. http://purl.obolibrary.org/obo/UBERON_0003012 flocculonodular lobe http://purl.obolibrary.org/obo/UBERON_0005293 cerebellum lobe The flocculonodular lobe is a lobe of the cerebellum consisting of the nodule and the flocculus. It is closely associated with the vestibulocerebellum. [WP,unvetted]. http://purl.obolibrary.org/obo/GO_0045686 negative regulation of glial cell differentiation http://purl.obolibrary.org/obo/GO_0045685 regulation of glial cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of glia cell differentiation. http://purl.obolibrary.org/obo/GO_0045687 positive regulation of glial cell differentiation http://purl.obolibrary.org/obo/GO_0045685 regulation of glial cell differentiation Any process that activates or increases the frequency, rate or extent of glia cell differentiation. http://purl.obolibrary.org/obo/UBERON_0003023 pontine tegmentum http://purl.obolibrary.org/obo/UBERON_0000064 organ part Dorsal portion of the pons, containing cranial nervee nuclei, ascending and descending tracts and reticular nuclei. It is continuous with the reticular formation of the medulla (Carpenter, A Core Text of Neuroanatomy, 3rd ed, 1985, pg 133). http://purl.obolibrary.org/obo/GO_0045727 positive regulation of translation http://purl.obolibrary.org/obo/GO_0010628 positive regulation of gene expression Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA. http://purl.obolibrary.org/obo/UBERON_0003037 septum http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure A wall, dividing a cavity or structure into smaller ones[WP]. http://purl.obolibrary.org/obo/GO_0045765 regulation of angiogenesis http://purl.obolibrary.org/obo/GO_1901342 regulation of vasculature development Any process that modulates the frequency, rate or extent of angiogenesis. http://purl.obolibrary.org/obo/UBERON_0003038 thoracic spinal cord http://purl.obolibrary.org/obo/UBERON_0005844 spinal cord segment The thoracic nerves are the spinal nerves emerging from the thoracic vertebrae. [WP,unvetted]. http://purl.obolibrary.org/obo/GO_0045785 positive regulation of cell adhesion http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the frequency, rate or extent of cell adhesion. http://purl.obolibrary.org/obo/UBERON_0003041 trigeminal nerve fibers http://purl.obolibrary.org/obo/UBERON_0006134 nerve fiber A nerve fiber that is part of a trigeminal nerve. http://purl.obolibrary.org/obo/GO_0045827 negative regulation of isoprenoid metabolic process http://purl.obolibrary.org/obo/GO_0045833 negative regulation of lipid metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving isoprenoid. http://purl.obolibrary.org/obo/UBERON_0003050 olfactory placode http://purl.obolibrary.org/obo/UBERON_0009955 neurogenic placode A thick plate of cells derived from the neural ectoderm in the head region of the embryo that develops into the olfactory region of the nasal cavity. http://purl.obolibrary.org/obo/GO_0045861 negative regulation of proteolysis http://purl.obolibrary.org/obo/GO_0051248 negative regulation of protein metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein. http://purl.obolibrary.org/obo/GO_0045862 positive regulation of proteolysis http://purl.obolibrary.org/obo/GO_0051247 positive regulation of protein metabolic process Any process that activates or increases the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein. http://purl.obolibrary.org/obo/UBERON_0003051 ear vesicle http://purl.obolibrary.org/obo/UBERON_0007499 epithelial sac An epithelial sac of invaginated ectoderm formed from the otic placode that gives rise to the structures of the inner ear[MP]. http://purl.obolibrary.org/obo/GO_0045912 negative regulation of carbohydrate metabolic process http://purl.obolibrary.org/obo/GO_0009892 negative regulation of metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving carbohydrate. http://purl.obolibrary.org/obo/GO_0045913 positive regulation of carbohydrate metabolic process http://purl.obolibrary.org/obo/GO_0009893 positive regulation of metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving carbohydrate. http://purl.obolibrary.org/obo/UBERON_0003052 midbrain-hindbrain boundary http://purl.obolibrary.org/obo/UBERON_0007651 anatomical junction The part of the brain that is the morphological boundary between the midbrain and hindbrain and that is the location of an organizing center which patterns the midbrain and hindbrain primordia of the neural plate. http://purl.obolibrary.org/obo/GO_0045934 negative regulation of nucleobase-containing compound metabolic process http://purl.obolibrary.org/obo/GO_0009892 negative regulation of metabolic process Any cellular process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids. http://purl.obolibrary.org/obo/UBERON_0003053 ventricular zone http://purl.obolibrary.org/obo/UBERON_0000477 anatomical cluster Proliferative region that is part of the ventricular system. http://purl.obolibrary.org/obo/UBERON_0003054 roof plate http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue A single row of glia at the dorsal midline of the developing neural tube along the entire anterior-posterior axis. This region provides inductive signals for the specification of neuronal cell types and of the specification of neural crest cells. The cells comprising the roof plate are the precursors to radial glial cells. http://purl.obolibrary.org/obo/GO_0045936 negative regulation of phosphate metabolic process http://purl.obolibrary.org/obo/GO_0010563 negative regulation of phosphorus metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving phosphates. http://purl.obolibrary.org/obo/GO_0045939 negative regulation of steroid metabolic process http://purl.obolibrary.org/obo/GO_0045833 negative regulation of lipid metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving steroids. http://purl.obolibrary.org/obo/UBERON_0003055 periderm http://purl.obolibrary.org/obo/UBERON_3000961 external integument structure The outermost layer (or layers, depending on the species) of embryonic skin, essential for the development of the epidermis and establishment of the barrier functions. The periderm derives from the outer layer of the ectoderm. http://purl.obolibrary.org/obo/GO_0045940 positive regulation of steroid metabolic process http://purl.obolibrary.org/obo/GO_0045834 positive regulation of lipid metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving steroids. http://purl.obolibrary.org/obo/UBERON_0003056 pre-chordal neural plate http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue The portion of neural plate anterior to the mid-hindbrain junction. http://purl.obolibrary.org/obo/GO_0045988 negative regulation of striated muscle contraction http://purl.obolibrary.org/obo/GO_0045932 negative regulation of muscle contraction Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle contraction. http://purl.obolibrary.org/obo/UBERON_0003057 chordal neural plate http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure The portion of neural plate posterior to the mid-hindbrain junction. http://purl.obolibrary.org/obo/UBERON_0003059 presomitic mesoderm http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure Unsegmented field of paraxial mesoderm present posterior to the most recently formed somite pair, from which somites will form. http://purl.obolibrary.org/obo/GO_0045989 positive regulation of striated muscle contraction http://purl.obolibrary.org/obo/GO_0045933 positive regulation of muscle contraction Any process that activates or increases the frequency, rate or extent of striated muscle contraction. http://purl.obolibrary.org/obo/UBERON_0003060 pronephric duct http://purl.obolibrary.org/obo/UBERON_0009201 nephric duct In mammals, the pronephric duct is the predecessor of the Wolffian duct[WP]. http://purl.obolibrary.org/obo/GO_0046185 aldehyde catabolic process http://purl.obolibrary.org/obo/GO_0009056 catabolic process The chemical reactions and pathways resulting in the breakdown of aldehydes, any organic compound with the formula R-CH=O. http://purl.obolibrary.org/obo/GO_0046395 carboxylic acid catabolic process http://purl.obolibrary.org/obo/GO_0016054 organic acid catabolic process The chemical reactions and pathways resulting in the breakdown of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups. http://purl.obolibrary.org/obo/UBERON_0003061 blood island http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure Blood islands are structures in the developing embryo which lead to many different parts of the circulatory system. They primarily derive from plexuses formed from angioblasts. Within them, vacuoles appear through liquefaction of the central part of the syncytium into plasma. The lumen of the blood vessels thus formed is probably intracellular. The flattened cells at the periphery form the endothelium. The nucleated red blood corpuscles develop either from small masses of the original angioblast left attached to the inner wall of the lumen or directly from the flat endothelial cells. In either case the syncytial mass thus formed projects from and is attached to the wall of the vessel. Such a mass is known as a blood island and hemoglobin gradually accumulates within it. Later the cells on the surface round up, giving the mass a mulberry-like appearance. Then the red blood cells break loose and are carried away in the plasma. Such free blood cells continue to divide. Blood islands have been seen in the area vasculosa in the omphalomesenteric vein and arteries, and in the dorsal aorta[WP, unvetted]. http://purl.obolibrary.org/obo/GO_0046434 organophosphate catabolic process http://purl.obolibrary.org/obo/GO_0009056 catabolic process The chemical reactions and pathways resulting in the breakdown of organophosphates, any phosphate-containing organic compound. http://purl.obolibrary.org/obo/GO_0046545 development of primary female sexual characteristics http://purl.obolibrary.org/obo/GO_0045137 development of primary sexual characteristics The process whose specific outcome is the progression of the primary female sexual characteristics over time, from their formation to the mature structure. The primary female sexual characteristics are the ovaries, and they develop in response to sex hormone secretion. http://purl.obolibrary.org/obo/UBERON_0003063 prechordal plate http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure A horseshoe-shaped thickening of the endoderm at the cranial (rostral) end of the primitive streak formed by the involution of Spemann's organizer cells which, together with the notochord, induces the formation of the neural plate from the overlying ectodermal cells and contributes mesodermal type cells to the surrounding tissue. http://purl.obolibrary.org/obo/GO_0046546 development of primary male sexual characteristics http://purl.obolibrary.org/obo/GO_0045137 development of primary sexual characteristics The process whose specific outcome is the progression of the primary male sexual characteristics over time, from their formation to the mature structures. The primary male sexual characteristics are the testes, and they develop in response to sex hormone secretion. http://purl.obolibrary.org/obo/GO_0046624 sphingolipid transporter activity http://purl.obolibrary.org/obo/GO_0005319 lipid transporter activity Enables the directed movement of sphingolipids into, out of or within a cell, or between cells. Sphingolipids are a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid). http://purl.obolibrary.org/obo/UBERON_0003064 intermediate mesoderm http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure The intermediate mesoderm is located between the lateral mesoderm and the paraxial mesoderm. It develops into the kidney and gonads. http://purl.obolibrary.org/obo/GO_0046825 regulation of protein export from nucleus http://purl.obolibrary.org/obo/GO_0046822 regulation of nucleocytoplasmic transport Any process that modulates the frequency, rate or extent of the directed movement of proteins from the nucleus to the cytoplasm. http://purl.obolibrary.org/obo/GO_0046831 regulation of RNA export from nucleus http://purl.obolibrary.org/obo/GO_0046822 regulation of nucleocytoplasmic transport Any process that modulates the frequency, rate or extent of the directed movement of RNA from the nucleus to the cytoplasm. http://purl.obolibrary.org/obo/UBERON_0003066 pharyngeal arch 2 http://purl.obolibrary.org/obo/UBERON_0002539 pharyngeal arch The second pharyngeal arch will form the hyoid apparatus. The cranial neural crest cells that populate the second pharyngeal arch emerge primarily from rhombomere 4 and will form skeletal elements. http://purl.obolibrary.org/obo/GO_0046836 glycolipid transport http://purl.obolibrary.org/obo/GO_1901264 carbohydrate derivative transport The directed movement of glycolipids, compounds containing (usually) 1-4 linked monosaccharide residues joined by a glycosyl linkage to a lipid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0046873 metal ion transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0008324 monoatomic cation transmembrane transporter activity Enables the transfer of metal ions from one side of a membrane to the other. http://purl.obolibrary.org/obo/UBERON_0003067 dorsolateral placode http://purl.obolibrary.org/obo/UBERON_0009955 neurogenic placode Lateral neurogenic placodes positioned dorsal of the epibranchial placodes. http://purl.obolibrary.org/obo/GO_0046886 positive regulation of hormone biosynthetic process http://purl.obolibrary.org/obo/GO_0009891 positive regulation of biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hormones. http://purl.obolibrary.org/obo/UBERON_0003068 axial mesoderm http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure The axial mesoderm includes the prechordal mesoderm and the chordamesoderm. It gives rise to the prechordal plate and to the notochord. http://purl.obolibrary.org/obo/GO_0046889 positive regulation of lipid biosynthetic process http://purl.obolibrary.org/obo/GO_0009891 positive regulation of biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids. http://purl.obolibrary.org/obo/GO_0046929 negative regulation of neurotransmitter secretion http://purl.obolibrary.org/obo/GO_1903531 negative regulation of secretion by cell Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a neurotransmitter. http://purl.obolibrary.org/obo/UBERON_0003069 otic placode http://purl.obolibrary.org/obo/UBERON_0003067 dorsolateral placode A cranial placode which, once specified, invaginates to form an otic cup, which eventually separates from the surface ectoderm to form the otic vesicle or otocyst, a rounded structure without appar- ent polarity. As the otic placode invaginates into a cup neuroblasts delaminate from the anterior ventral aspect of the otic epithelium to give rise to neurons of the vestibulocochlear (statoacoustic) ganglion of cranial nerve VIII[NBK]. http://purl.obolibrary.org/obo/GO_0048242 epinephrine secretion http://purl.obolibrary.org/obo/GO_0050432 catecholamine secretion The regulated release of epinephrine by a cell. Epinephrine is a catecholamine hormone secreted by the adrenal medulla and a neurotransmitter, released by certain neurons and active in the central nervous system. http://purl.obolibrary.org/obo/UBERON_0003070 trigeminal placode complex http://purl.obolibrary.org/obo/UBERON_0003067 dorsolateral placode A neurogenic placode that arises at the level of the midbrain-hindbrain boundary and develops into a trigeminal ganglion. http://purl.obolibrary.org/obo/GO_0048243 norepinephrine secretion http://purl.obolibrary.org/obo/GO_0050432 catecholamine secretion The regulated release of norepinephrine by a cell. Norepinephrine is a catecholamine and it acts as a hormone and as a neurotransmitter of most of the sympathetic nervous system. http://purl.obolibrary.org/obo/UBERON_0003072 optic cup http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure Multi-tissue structure that is comprised of neural and non-neural epithelial layers which will form the retina and retinal pigmented epithelium of the mature eye[ZFA]. double walled structured formed by expansion and invagination of the distal end of the optic vesicle that develops into the pigmented and sensory layers of the retina while the mouth of the optic cup eventually forms the pupil of the eye[MP]. http://purl.obolibrary.org/obo/GO_0048246 macrophage chemotaxis http://purl.obolibrary.org/obo/GO_0030595 leukocyte chemotaxis The movement of a macrophage in response to an external stimulus. http://purl.obolibrary.org/obo/GO_0048520 positive regulation of behavior http://purl.obolibrary.org/obo/GO_0050795 regulation of behavior Any process that activates or increases the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli. http://purl.obolibrary.org/obo/UBERON_0003073 lens placode http://purl.obolibrary.org/obo/UBERON_0011814 non-neurogenic ectodermal placode A thickened portion of ectoderm which serves as the precursor to the lens. SOX2 and Pou2f1 are involved in its development[WP]. http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. http://purl.obolibrary.org/obo/UBERON_0003075 neural plate http://purl.obolibrary.org/obo/UBERON_0016879 future central nervous system A region of embryonic ectodermal cells that lie directly above the notochord. During neurulation, they change shape and produce an infolding of the neural plate (the neural fold) that then seals to form the neural tube[XAO]. The earliest recognizable dorsal ectodermal primordium of the central nervous system present near the end of gastrulation before infolding to form the neural keel; consists of a thickened pseudostratified epithelium[ZFA]. http://purl.obolibrary.org/obo/GO_0048570 notochord morphogenesis http://purl.obolibrary.org/obo/GO_0048562 embryonic organ morphogenesis The process in which the anatomical structures of the notochord are generated and organized. The notochord is a mesoderm-derived structure located ventral of the developing nerve cord. In vertebrates, the notochord serves as a core around which other mesodermal cells form the vertebrae. In the most primitive chordates, which lack vertebrae, the notochord persists as a substitute for a vertebral column. http://purl.obolibrary.org/obo/UBERON_0003077 paraxial mesoderm http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure The paraxial mesoderm is the mesoderm located bilaterally adjacent to the notochord and neural tube[GO]. http://purl.obolibrary.org/obo/UBERON_0003078 epibranchial placode http://purl.obolibrary.org/obo/UBERON_0009955 neurogenic placode Focal thickenings of the embryonic ectoderm that form immediately dorsal and caudal of the clefts between the pharyngeal arches and that produce the neuroblasts that migrate and condense to form the distal cranial ganglia. http://purl.obolibrary.org/obo/GO_0048581 negative regulation of post-embryonic development http://purl.obolibrary.org/obo/GO_0051241 negative regulation of multicellular organismal process Any process that stops, prevents, or reduces the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. http://purl.obolibrary.org/obo/UBERON_0003079 floor plate http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue The specialized glial structure (non-neuronal cells) situated at the ventral midline of the embryonic neural tube; this structure spans the anteroposterior axis from the midbrain to the tail regions, separating the left and right basal plates of the developing neural tube, and serves as an organizer to ventralize tissues in the embryo as well as to guide neuronal positioning and differentiation along the dorsoventral axis of the neural tube. http://purl.obolibrary.org/obo/GO_0048582 positive regulation of post-embryonic development http://purl.obolibrary.org/obo/GO_0051240 positive regulation of multicellular organismal process Any process that activates or increases the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. http://purl.obolibrary.org/obo/UBERON_0003081 lateral plate mesoderm http://purl.obolibrary.org/obo/UBERON_0007524 dense mesenchyme tissue Portion of the middle of the three primary germ layers of the embryo that resides on the periphery of the embryo, is continuous with the extra-embryonic mesoderm, splits into two layers enclosing the intra-embryonic coelom, and gives rise to body wall structures[MP]. http://purl.obolibrary.org/obo/GO_0048628 myoblast maturation http://purl.obolibrary.org/obo/GO_0048469 cell maturation A developmental process, independent of morphogenetic (shape) change, that is required for a myoblast to attain its fully functional state. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. http://purl.obolibrary.org/obo/UBERON_0003082 myotome http://purl.obolibrary.org/obo/UBERON_0017650 developing mesenchymal structure A transitional population of migrating mesenchymal cells that derive from somites and that will become muscle cells. http://purl.obolibrary.org/obo/GO_0048634 regulation of muscle organ development http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of muscle development. http://purl.obolibrary.org/obo/GO_0048635 negative regulation of muscle organ development http://purl.obolibrary.org/obo/GO_0048634 regulation of muscle organ development Any process that stops, prevents, or reduces the frequency, rate or extent of muscle development. http://purl.obolibrary.org/obo/UBERON_0003083 trunk neural crest http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue Trunk portion of the neural crest. The trunk neural crest lies between the vagal and sacral neural crest and gives rise to two groups of cells. One group migrates dorsolateral and populates the skin, forming pigment cells and the other migrates ventrolateral through the anterior sclerotome to become the epinephrine-producing cells of the adrenal gland and the neurons of the sympathetic nervous system. Some cells remain in the sclerotome to form the dorsal root ganglia [Wikipedia]. http://purl.obolibrary.org/obo/GO_0048636 positive regulation of muscle organ development http://purl.obolibrary.org/obo/GO_0048634 regulation of muscle organ development Any process that activates, maintains or increases the rate of muscle development. http://purl.obolibrary.org/obo/GO_0048638 regulation of developmental growth http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of developmental growth. http://purl.obolibrary.org/obo/UBERON_0003084 heart primordium http://purl.obolibrary.org/obo/UBERON_0001048 primordium Bilateral groups of cells consisting of three rows: one row of endocardial precursors medially and two rows of myocardical precursors laterally. The two populations fuse at the midline to form the heart rudiment or cone. http://purl.obolibrary.org/obo/GO_0048641 regulation of skeletal muscle tissue development http://purl.obolibrary.org/obo/GO_0016202 regulation of striated muscle tissue development Any process that modulates the frequency, rate or extent of skeletal muscle tissue development. http://purl.obolibrary.org/obo/UBERON_0003086 caudal artery http://purl.obolibrary.org/obo/UBERON_0003524 tail blood vessel Extension of the dorsal aorta in the tail. http://purl.obolibrary.org/obo/GO_0048642 negative regulation of skeletal muscle tissue development http://purl.obolibrary.org/obo/GO_0048641 regulation of skeletal muscle tissue development Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle tissue development. http://purl.obolibrary.org/obo/UBERON_0003089 sclerotome http://purl.obolibrary.org/obo/UBERON_0007530 migrating mesenchyme population Ventral somitic compartment that is a precursor of the axial skeleton[XAO]. Sclerotomes eventually differentiate into the vertebrae and most of the skull. The caudal (posterior) half of one sclerotome fuses with the rostral (anterior) half of the adjacent one to form each vertebra. From their initial location within the somite, the sclerotome cells migrate medially towards the notochord. These cells meet the sclerotome cells from the other side to form the vertebral body. From this vertebral body, sclerotome cells move dorsally and surround the developing spinal cord, forming the vertebral arch[WP]. http://purl.obolibrary.org/obo/GO_0048643 positive regulation of skeletal muscle tissue development http://purl.obolibrary.org/obo/GO_0048641 regulation of skeletal muscle tissue development Any process that activates, maintains or increases the rate of skeletal muscle tissue development. http://purl.obolibrary.org/obo/GO_0048708 astrocyte differentiation http://purl.obolibrary.org/obo/GO_0010001 glial cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of an astrocyte. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function. http://purl.obolibrary.org/obo/UBERON_0003091 thyroid primordium http://purl.obolibrary.org/obo/UBERON_0004119 endoderm-derived structure The initial thyroid precursor, the thyroid primordium, starts as a simple midline thickening and develops to form the thyroid diverticulum. This structure is initially hollow, although it later solidifies and becomes bilobed. The 2 lobes are located on either side of the midline and are connected via an isthmus. http://purl.obolibrary.org/obo/GO_0048709 oligodendrocyte differentiation http://purl.obolibrary.org/obo/GO_0010001 glial cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of an oligodendrocyte. An oligodendrocyte is a type of glial cell involved in myelinating the axons of neurons in the central nervous system. http://purl.obolibrary.org/obo/GO_0048863 stem cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a stem cell. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells. http://purl.obolibrary.org/obo/UBERON_0003098 optic stalk http://purl.obolibrary.org/obo/UBERON_0034705 developing neuroepithelium The narrow, proximal portion of the optic vesicle which connects the embryonic eye and forebrain. http://purl.obolibrary.org/obo/GO_0048864 stem cell development http://purl.obolibrary.org/obo/GO_0048468 cell development The process whose specific outcome is the progression of the stem cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to its specific fate. http://purl.obolibrary.org/obo/UBERON_0003099 cranial neural crest http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue Neural crest cells (NCCs) originating in the anterior part of the developing embryo and residing between the mid-diencephalon and the forming hindbrain; cranial NCCs migrate dorsolaterally to form the craniofacial mesenchyme that differentiates into various craniofacial cartilages and bones, cranial neurons, glia, and connective tissues of the face; these cells enter the pharyngeal pouches and arches where they give rise to thymic cells, bones of the middle ear and jaw (mandible), and the odontoblasts of the tooth primordia; like their counterparts in the trunk, cranial NCCs also contribute to the developing peripheral nervous system, along with the pigmented cell (i.e. melanocyte) lineage. http://purl.obolibrary.org/obo/GO_0048878 chemical homeostasis http://purl.obolibrary.org/obo/GO_0042592 homeostatic process Any biological process involved in the maintenance of an internal steady state of a chemical. http://purl.obolibrary.org/obo/GO_0050432 catecholamine secretion http://purl.obolibrary.org/obo/GO_0051937 catecholamine transport The regulated release of catecholamines by a cell. The catecholamines are a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine. http://purl.obolibrary.org/obo/UBERON_0003100 female organism http://purl.obolibrary.org/obo/UBERON_0000468 multicellular organism Gonochoristic organism that can produce female gametes. http://purl.obolibrary.org/obo/GO_0050433 regulation of catecholamine secretion http://purl.obolibrary.org/obo/GO_0051952 regulation of amine transport Any process that modulates the frequency, rate or extent of the regulated release of catecholamines. http://purl.obolibrary.org/obo/GO_0050767 regulation of neurogenesis http://purl.obolibrary.org/obo/GO_0060284 regulation of cell development Any process that modulates the frequency, rate or extent of neurogenesis, the generation of cells in the nervous system. http://purl.obolibrary.org/obo/UBERON_0003101 male organism http://purl.obolibrary.org/obo/UBERON_0000468 multicellular organism Gonochoristic organism that can produce male gametes. http://purl.obolibrary.org/obo/GO_0050790 regulation of catalytic activity http://purl.obolibrary.org/obo/GO_0065009 regulation of molecular function Any process that modulates the activity of an enzyme. http://purl.obolibrary.org/obo/UBERON_0003102 surface structure http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure Anatomical structure that overlaps the outer epithelial layer and is adjacent to the space surrounding the organism. http://purl.obolibrary.org/obo/UBERON_0003103 compound organ http://purl.obolibrary.org/obo/UBERON_0000062 organ Anatomical structure that has as its parts two or more multi-tissue structures of at least two different types and which through specific morphogenetic processes forms a single distinct structural unit demarcated by bona fide boundaries from other distinct anatomical structures of different types. http://purl.obolibrary.org/obo/GO_0050810 regulation of steroid biosynthetic process http://purl.obolibrary.org/obo/GO_0046890 regulation of lipid biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus. http://purl.obolibrary.org/obo/GO_0050832 defense response to fungus http://purl.obolibrary.org/obo/GO_0009620 response to fungus Reactions triggered in response to the presence of a fungus that act to protect the cell or organism. http://purl.obolibrary.org/obo/UBERON_0003104 mesenchyme http://purl.obolibrary.org/obo/UBERON_0000479 tissue Portion of tissue composed of mesenchymal cells (motile cells that develop from epthelia via an epithelial to mesenchymal transition) and surrounding extracellular material. Mesenchyme has different embryological origins in different metazoan taxa - in many invertebrates it derives in whole or part from ectoderm. In vertebrates it derives largely from mesoderm, and sometimes the terms are used interchangeably, e.g. lateral plate mesoderm/mesenchyme. http://purl.obolibrary.org/obo/GO_0050848 regulation of calcium-mediated signaling http://purl.obolibrary.org/obo/GO_1902531 regulation of intracellular signal transduction Any process that modulates the frequency, rate or extent of calcium-mediated signaling, the process in which a cell uses calcium ions to convert an extracellular signal into a response. http://purl.obolibrary.org/obo/GO_0050879 multicellular organismal movement http://purl.obolibrary.org/obo/GO_0032501 multicellular organismal process Any physiological process involved in changing the position of a multicellular organism or an anatomical part of a multicellular organism. http://purl.obolibrary.org/obo/UBERON_0003111 sphenoid region http://purl.obolibrary.org/obo/UBERON_0034921 multi organ part structure Anatomical cluster that forms the floor and sidewalls of the middle part of the cranium. http://purl.obolibrary.org/obo/UBERON_0003112 olfactory region http://purl.obolibrary.org/obo/UBERON_0034921 multi organ part structure Anatomical cluster that is located in the anterior region of the cranium and provides structural support for the olfactory organ. http://purl.obolibrary.org/obo/GO_0050910 detection of mechanical stimulus involved in sensory perception of sound http://purl.obolibrary.org/obo/GO_0050877 nervous system process The series of events involved in the perception of sound vibration in which the vibration is received and converted into a molecular signal. http://purl.obolibrary.org/obo/UBERON_0003113 dermatocranium http://purl.obolibrary.org/obo/UBERON_0011159 primary subdivision of cranial skeletal system Subdivision of skeleton that includes all dermal bones in the cranial skeleton[ZFA,modified]. http://purl.obolibrary.org/obo/GO_0050981 detection of electrical stimulus http://purl.obolibrary.org/obo/GO_0051602 response to electrical stimulus The series of events by which an electrical stimulus is received and converted into a molecular signal. http://purl.obolibrary.org/obo/UBERON_0003114 pharyngeal arch 3 http://purl.obolibrary.org/obo/UBERON_0002539 pharyngeal arch The third branchial arch contributes to the development of the hyoid bone, stylopharyngeus muscle, inferior parathyroid gland, and thymus. http://purl.obolibrary.org/obo/GO_0050994 regulation of lipid catabolic process http://purl.obolibrary.org/obo/GO_0009894 regulation of catabolic process Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of lipids. http://purl.obolibrary.org/obo/GO_0050995 negative regulation of lipid catabolic process http://purl.obolibrary.org/obo/GO_0050994 regulation of lipid catabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of lipids. http://purl.obolibrary.org/obo/UBERON_0003115 pharyngeal arch 4 http://purl.obolibrary.org/obo/UBERON_0002539 pharyngeal arch Contributes to development of the cartilage of the larynx, laryngeal, pharyngeal, and soft palate muscles, superior parathyroid gland, and C-cells of the thymus. http://purl.obolibrary.org/obo/UBERON_0003117 pharyngeal arch 6 http://purl.obolibrary.org/obo/UBERON_0002539 pharyngeal arch The 6th pharyngeal arch. contributes to the development of the sternocleidomastoid and trapezius muscles. http://purl.obolibrary.org/obo/GO_0050996 positive regulation of lipid catabolic process http://purl.obolibrary.org/obo/GO_0050994 regulation of lipid catabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of lipids. http://purl.obolibrary.org/obo/UBERON_0003118 pharyngeal arch artery 1 http://purl.obolibrary.org/obo/UBERON_0004363 pharyngeal arch artery The vessels formed within the first pair of branchial arches in embryogenesis. http://purl.obolibrary.org/obo/GO_0051027 DNA transport http://purl.obolibrary.org/obo/GO_0050657 nucleic acid transport The directed movement of RNA, deoxyribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0051035 DNA transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0051032 nucleic acid transmembrane transporter activity Enables the transfer of DNA, deoxyribonucleic acid, from one side of a membrane to the other. http://purl.obolibrary.org/obo/UBERON_0003119 pharyngeal arch artery 2 http://purl.obolibrary.org/obo/UBERON_0004363 pharyngeal arch artery The vessels formed within the second pair of branchial arches in embryogenesis. http://purl.obolibrary.org/obo/UBERON_0003120 pharyngeal arch artery 3 http://purl.obolibrary.org/obo/UBERON_0004363 pharyngeal arch artery The vessels formed within the third pair of branchial arches in embryogenesis. http://purl.obolibrary.org/obo/GO_0051049 regulation of transport http://purl.obolibrary.org/obo/GO_0032879 regulation of localization Any process that modulates the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/UBERON_0003121 pharyngeal arch artery 4 http://purl.obolibrary.org/obo/UBERON_0004363 pharyngeal arch artery The vessels formed within the fourth pair of branchial arches in embryogenesis. http://purl.obolibrary.org/obo/GO_0051050 positive regulation of transport http://purl.obolibrary.org/obo/GO_0051049 regulation of transport Any process that activates or increases the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/UBERON_0003122 pharyngeal arch artery 5 http://purl.obolibrary.org/obo/UBERON_0004363 pharyngeal arch artery The vessels formed within the fifth pair of pharyngeal arches in embryogenesis. http://purl.obolibrary.org/obo/GO_0051051 negative regulation of transport http://purl.obolibrary.org/obo/GO_0051049 regulation of transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/UBERON_0003123 pharyngeal arch artery 6 http://purl.obolibrary.org/obo/UBERON_0004363 pharyngeal arch artery The vessels formed within the sixth pair of branchial arches in embryogenesis. http://purl.obolibrary.org/obo/UBERON_0003124 chorion membrane http://purl.obolibrary.org/obo/UBERON_0005631 extraembryonic membrane The outermost extraembryonic membrane of amniotes. http://purl.obolibrary.org/obo/GO_0051055 negative regulation of lipid biosynthetic process http://purl.obolibrary.org/obo/GO_0009890 negative regulation of biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids. http://purl.obolibrary.org/obo/UBERON_0003127 open tracheal system trachea http://purl.obolibrary.org/obo/UBERON_0001005 respiratory airway A respiratory airway that is part of an open tracheal system. http://purl.obolibrary.org/obo/GO_0051129 negative regulation of cellular component organization http://purl.obolibrary.org/obo/GO_0051128 regulation of cellular component organization Any process that stops, prevents, or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope. http://purl.obolibrary.org/obo/UBERON_0003128 cranium http://purl.obolibrary.org/obo/UBERON_0000075 subdivision of skeletal system Upper portion of the skull that excludes the mandible (when present in the organism). http://purl.obolibrary.org/obo/UBERON_0003209 blood nerve barrier http://purl.obolibrary.org/obo/UBERON_0000119 cell layer Barrier between the perineurium of peripheral nerves and the vascular endothelium of endoneurial capillaries. The perineurium acts as a diffusion barrier, but ion permeability at the blood-nerve barrier is still higher than at the blood-brain barrier[GO]. http://purl.obolibrary.org/obo/GO_0051130 positive regulation of cellular component organization http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope. http://purl.obolibrary.org/obo/UBERON_0003210 blood-cerebrospinal fluid barrier http://purl.obolibrary.org/obo/UBERON_0000119 cell layer Barrier in the choroid plexus located in the lateral, third, and fourth brain ventricles that controls the entrance of substances into the cerebrospinal fluid from the blood[MP]. http://purl.obolibrary.org/obo/GO_0051146 striated muscle cell differentiation http://purl.obolibrary.org/obo/GO_0042692 muscle cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a striated muscle cell; striated muscle fibers are divided by transverse bands into striations, and cardiac and voluntary muscle are types of striated muscle. http://purl.obolibrary.org/obo/UBERON_0003212 gustatory organ http://purl.obolibrary.org/obo/UBERON_0000005 chemosensory organ Any sense organ that functions in (some) detection of chemical stimulus involved in sensory perception of taste (GO:0050912). http://purl.obolibrary.org/obo/GO_0051153 regulation of striated muscle cell differentiation http://purl.obolibrary.org/obo/GO_0051147 regulation of muscle cell differentiation Any process that modulates the frequency, rate or extent of striated muscle cell differentiation. http://purl.obolibrary.org/obo/UBERON_0003214 mammary gland alveolus http://purl.obolibrary.org/obo/UBERON_0003215 alveolus A sac-like structure that is found in the mature gland[GO]. http://purl.obolibrary.org/obo/GO_0051154 negative regulation of striated muscle cell differentiation http://purl.obolibrary.org/obo/GO_0051153 regulation of striated muscle cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle cell differentiation. http://purl.obolibrary.org/obo/UBERON_0003215 alveolus http://purl.obolibrary.org/obo/UBERON_0000064 organ part Organ part that has the form of a hollow cavity[WP]. http://purl.obolibrary.org/obo/UBERON_0003218 ovary septum http://purl.obolibrary.org/obo/UBERON_0003037 septum Septum that divides the ovary, the basal portion of a carpel or group of fused carpels, that encloses the ovule(s)[GO]. http://purl.obolibrary.org/obo/GO_0051155 positive regulation of striated muscle cell differentiation http://purl.obolibrary.org/obo/GO_0051153 regulation of striated muscle cell differentiation Any process that activates or increases the frequency, rate or extent of striated muscle cell differentiation. http://purl.obolibrary.org/obo/GO_0051174 regulation of phosphorus metabolic process http://purl.obolibrary.org/obo/GO_0019222 regulation of metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus. http://purl.obolibrary.org/obo/UBERON_0003220 metanephric mesenchyme http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure One of the two embryological structures that give rise to the kidney (the other is the ureteric bud). The metanephric blastema mostly develops into nephrons, but can also form parts of the collecting duct system.[WP]. Metanephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the metanephros[GO]. http://purl.obolibrary.org/obo/GO_0051209 release of sequestered calcium ion into cytosol http://purl.obolibrary.org/obo/GO_0097553 calcium ion transmembrane import into cytosol The process in which calcium ions sequestered in the endoplasmic reticulum, Golgi apparatus or mitochondria are released into the cytosolic compartment. http://purl.obolibrary.org/obo/UBERON_0003224 chorion syncytiotrophoblast http://purl.obolibrary.org/obo/UBERON_0000478 extraembryonic structure An extraembryonic structure that develops_from a syncytiotrophoblast and is part of a chorion. http://purl.obolibrary.org/obo/GO_0051279 regulation of release of sequestered calcium ion into cytosol http://purl.obolibrary.org/obo/GO_1903169 regulation of calcium ion transmembrane transport Any process that modulates the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria. http://purl.obolibrary.org/obo/UBERON_0003229 epithelium of elbow http://purl.obolibrary.org/obo/UBERON_0000483 epithelium An epithelium that is part of a elbow [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003230 epithelium of carpal region http://purl.obolibrary.org/obo/UBERON_0000490 unilaminar epithelium An epithelium that is part of a wrist [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0051336 regulation of hydrolase activity http://purl.obolibrary.org/obo/GO_0050790 regulation of catalytic activity Any process that modulates the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3. http://purl.obolibrary.org/obo/UBERON_0003231 epithelium of hip http://purl.obolibrary.org/obo/UBERON_0000483 epithelium An epithelium that is part of a hip [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0051345 positive regulation of hydrolase activity http://purl.obolibrary.org/obo/GO_0051336 regulation of hydrolase activity Any process that activates or increases the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds. http://purl.obolibrary.org/obo/UBERON_0003232 epithelium of knee http://purl.obolibrary.org/obo/UBERON_0000483 epithelium An epithelium that is part of a knee [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0051346 negative regulation of hydrolase activity http://purl.obolibrary.org/obo/GO_0051336 regulation of hydrolase activity Any process that stops or reduces the rate of hydrolase activity, the catalysis of the hydrolysis of various bonds. http://purl.obolibrary.org/obo/UBERON_0003233 epithelium of shoulder http://purl.obolibrary.org/obo/UBERON_0000483 epithelium An epithelium that is part of a shoulder [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003235 epithelium of upper jaw http://purl.obolibrary.org/obo/UBERON_0035037 jaw epithelium An epithelium that is part of a upper jaw [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0051450 myoblast proliferation http://purl.obolibrary.org/obo/GO_0008283 cell population proliferation The multiplication or reproduction of myoblasts, resulting in the expansion of a myoblast cell population. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. http://purl.obolibrary.org/obo/UBERON_0003236 epithelium of lower jaw http://purl.obolibrary.org/obo/UBERON_0035037 jaw epithelium An epithelium that is part of a lower jaw [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0051451 myoblast migration http://purl.obolibrary.org/obo/GO_0014812 muscle cell migration The orderly movement of a myoblast from one site to another, often during the development of a multicellular organism. A myoblast is a cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. http://purl.obolibrary.org/obo/UBERON_0003241 epithelium of utricle http://purl.obolibrary.org/obo/UBERON_0006932 vestibular epithelium An epithelium that is part of a utricle of membranous labyrinth [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0051494 negative regulation of cytoskeleton organization http://purl.obolibrary.org/obo/GO_0010639 negative regulation of organelle organization Any process that stops, prevents, or reduces the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures. http://purl.obolibrary.org/obo/UBERON_0003242 epithelium of saccule http://purl.obolibrary.org/obo/UBERON_0006932 vestibular epithelium An epithelium that is part of a saccule of membranous labyrinth [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003243 epithelium of cochlear duct http://purl.obolibrary.org/obo/UBERON_0006937 inner ear epithelium An epithelium that is part of a cochlear duct of membranous labyrinth [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0051495 positive regulation of cytoskeleton organization http://purl.obolibrary.org/obo/GO_0010638 positive regulation of organelle organization Any process that activates or increases the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures. http://purl.obolibrary.org/obo/UBERON_0003244 epithelium of mammary gland http://purl.obolibrary.org/obo/UBERON_0000483 epithelium The epithelial layer of the luminal surfaces of the mammary gland. http://purl.obolibrary.org/obo/GO_0051602 response to electrical stimulus http://purl.obolibrary.org/obo/GO_0009628 response to abiotic stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus. http://purl.obolibrary.org/obo/UBERON_0003247 epithelium of forearm http://purl.obolibrary.org/obo/UBERON_0000483 epithelium An epithelium that is part of a lower arm [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0051606 detection of stimulus http://purl.obolibrary.org/obo/GO_0050896 response to stimulus The series of events in which a stimulus is received by a cell or organism and converted into a molecular signal. http://purl.obolibrary.org/obo/UBERON_0003248 epithelium of footplate http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue An epithelium that is part of a footplate. http://purl.obolibrary.org/obo/GO_0051640 organelle localization http://purl.obolibrary.org/obo/GO_0051179 localization Any process in which an organelle is transported to, and/or maintained in, a specific location. http://purl.obolibrary.org/obo/UBERON_0003249 epithelium of otic placode http://purl.obolibrary.org/obo/UBERON_0015807 ear epithelium An epithelium that is part of a otic placode [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0051667 establishment of plastid localization http://purl.obolibrary.org/obo/GO_0051656 establishment of organelle localization The directed movement of a plastid to a specific location in the cell. http://purl.obolibrary.org/obo/UBERON_0003252 thoracic rib cage http://purl.obolibrary.org/obo/UBERON_0010912 subdivision of skeleton Subdivision of skeletal system that consists of all ribs in an organism connected to the sternum and the vertebrae. Some vertebrates have abdominal ribs (gastrialia), not connected to the vertebrate - these are not considered part of the rib case. http://purl.obolibrary.org/obo/GO_0051881 regulation of mitochondrial membrane potential http://purl.obolibrary.org/obo/GO_0042391 regulation of membrane potential Any process that modulates the establishment or extent of the mitochondrial membrane potential, the electric potential existing across the mitochondrial membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane. http://purl.obolibrary.org/obo/UBERON_0003253 neck of rib http://purl.obolibrary.org/obo/UBERON_0018664 neck of bone element The neck of the rib is the flattened portion which extends lateralward from the head; it is about 2.5 cm. long, and is placed in front of the transverse process of the lower of the two vertebrC& with which the head articulates. Its anterior surface is flat and smooth, its posterior rough for the attachment of the ligament of the neck, and perforated by numerous foramina. Of its two borders the superior presents a rough crest (crista colli costE) for the attachment of the anterior costotransverse ligament; its inferior border is rounded. On the posterior surface at the junction of the neck and body, and nearer the lower than the upper border, is an eminencebthe tubercle; it consists of an articular and a non-articular portion. The articular portion, the lower and more medial of the two, presents a small, oval surface for articulation with the end of the transverse process of the lower of the two vertebrC& to which the head is connected. The non-articular portion is a rough elevation, and affords attachment to the ligament of the tubercle. The tubercle is much more prominent in the upper than in the lower ribs. http://purl.obolibrary.org/obo/GO_0051892 negative regulation of cardioblast differentiation http://purl.obolibrary.org/obo/GO_0051890 regulation of cardioblast differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. http://purl.obolibrary.org/obo/GO_0051924 regulation of calcium ion transport http://purl.obolibrary.org/obo/GO_0010959 regulation of metal ion transport Any process that modulates the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/UBERON_0003257 yolk sac endoderm http://purl.obolibrary.org/obo/UBERON_0005911 endo-epithelium The portion of the yolk sac that is derived from endoderm and lines the yolk sac. http://purl.obolibrary.org/obo/GO_0051926 negative regulation of calcium ion transport http://purl.obolibrary.org/obo/GO_0051924 regulation of calcium ion transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0051928 positive regulation of calcium ion transport http://purl.obolibrary.org/obo/GO_0051924 regulation of calcium ion transport Any process that activates or increases the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/UBERON_0003258 endoderm of foregut http://purl.obolibrary.org/obo/UBERON_0015833 foregut epithelium An endoderm that is part of a foregut [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0051937 catecholamine transport http://purl.obolibrary.org/obo/GO_0015850 organic hydroxy compound transport The directed movement of catecholamines, a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine. http://purl.obolibrary.org/obo/UBERON_0003259 endoderm of midgut http://purl.obolibrary.org/obo/UBERON_0005911 endo-epithelium An endoderm that is part of a midgut [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003260 endoderm of hindgut http://purl.obolibrary.org/obo/UBERON_0005911 endo-epithelium An endoderm that is part of a hindgut [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0051952 regulation of amine transport http://purl.obolibrary.org/obo/GO_0051049 regulation of transport Any process that modulates the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/UBERON_0003261 thyroid primordium endoderm http://purl.obolibrary.org/obo/UBERON_0004119 endoderm-derived structure An endoderm that is part of a thyroid primordium. http://purl.obolibrary.org/obo/UBERON_0003262 amniotic mesoderm http://purl.obolibrary.org/obo/UBERON_0010333 extraembryonic membrane mesenchyme A mesenchyme that is part of a amnion. http://purl.obolibrary.org/obo/GO_0051953 negative regulation of amine transport http://purl.obolibrary.org/obo/GO_0051952 regulation of amine transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/UBERON_0003265 chorionic mesenchyme http://purl.obolibrary.org/obo/UBERON_0010333 extraembryonic membrane mesenchyme A mesenchyme that is part of a chorion. http://purl.obolibrary.org/obo/GO_0051954 positive regulation of amine transport http://purl.obolibrary.org/obo/GO_0051952 regulation of amine transport Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/UBERON_0003267 tooth of upper jaw http://purl.obolibrary.org/obo/UBERON_0013765 digestive system element A calcareous tooth that is part of the upper jaw region. In mammals, the upper jaw teeth are attached to the maxilla. http://purl.obolibrary.org/obo/GO_0051963 regulation of synapse assembly http://purl.obolibrary.org/obo/GO_1901888 regulation of cell junction assembly Any process that modulates the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse. http://purl.obolibrary.org/obo/UBERON_0003268 tooth of lower jaw http://purl.obolibrary.org/obo/UBERON_0013765 digestive system element A calcareous tooth that is part of the lower jaw region. In mammals, the lower jaw teeth are attached to the mandible (dentary). http://purl.obolibrary.org/obo/GO_0055002 striated muscle cell development http://purl.obolibrary.org/obo/GO_0055001 muscle cell development The process whose specific outcome is the progression of a striated muscle cell over time, from its formation to the mature structure. Striated muscle cells contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle. http://purl.obolibrary.org/obo/UBERON_0003269 skeletal muscle tissue of eye http://purl.obolibrary.org/obo/UBERON_0001134 skeletal muscle tissue A portion of skeletal muscle tissue that is part of a eye [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003277 skeleton of upper jaw http://purl.obolibrary.org/obo/UBERON_0010912 subdivision of skeleton A subdivision of the skeleton that corresponds to the upper part of the mouth. The lower jaw skeleton includes the following elements, when present: upper jaw teeth, the maxilla and other lower jaw bones. http://purl.obolibrary.org/obo/GO_0055088 lipid homeostasis http://purl.obolibrary.org/obo/GO_0048878 chemical homeostasis Any process involved in the maintenance of an internal steady state of lipid within an organism or cell. http://purl.obolibrary.org/obo/GO_0055117 regulation of cardiac muscle contraction http://purl.obolibrary.org/obo/GO_0008016 regulation of heart contraction Any process that modulates the frequency, rate or extent of cardiac muscle contraction. http://purl.obolibrary.org/obo/UBERON_0003278 skeleton of lower jaw http://purl.obolibrary.org/obo/UBERON_0010912 subdivision of skeleton A subdivision of the skeleton that corresponds to the lower part of the mouth. The lower jaw skeleton includes the following elements, when present: lower jaw teeth, the mandible and other lower jaw bones, and Meckel's cartilage. http://purl.obolibrary.org/obo/GO_0060042 retina morphogenesis in camera-type eye http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structure of the retina is generated and organized. http://purl.obolibrary.org/obo/UBERON_0003279 endothelium of trachea http://purl.obolibrary.org/obo/UBERON_0001986 endothelium An endothelium that is part of a trachea. http://purl.obolibrary.org/obo/GO_0060048 cardiac muscle contraction http://purl.obolibrary.org/obo/GO_0006941 striated muscle contraction Muscle contraction of cardiac muscle tissue. http://purl.obolibrary.org/obo/UBERON_0003281 mesentery of stomach http://purl.obolibrary.org/obo/UBERON_0004854 gastrointestinal system mesentery The portion of the primitive mesentery that encloses the stomach; from its dorsal sheet, the greater omentum develops, and from its ventral sheet, the lesser omentum. http://purl.obolibrary.org/obo/GO_0060251 regulation of glial cell proliferation http://purl.obolibrary.org/obo/GO_0042127 regulation of cell population proliferation Any process that modulates the frequency, rate or extent of glial cell proliferation. http://purl.obolibrary.org/obo/UBERON_0003282 mesentery of heart http://purl.obolibrary.org/obo/UBERON_0002095 mesentery A mesentery that surrounds the heart. http://purl.obolibrary.org/obo/GO_0060252 positive regulation of glial cell proliferation http://purl.obolibrary.org/obo/GO_0060251 regulation of glial cell proliferation Any process that activates or increases the rate or extent of glial cell proliferation. http://purl.obolibrary.org/obo/UBERON_0003283 mesentery of oesophagus http://purl.obolibrary.org/obo/UBERON_0002095 mesentery A mesentery that is part of a esophagus [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003284 mesentery of midgut http://purl.obolibrary.org/obo/UBERON_0002095 mesentery A mesentery that is part of a midgut [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060253 negative regulation of glial cell proliferation http://purl.obolibrary.org/obo/GO_0060251 regulation of glial cell proliferation Any process that stops or decreases the rate or extent of glial cell proliferation. http://purl.obolibrary.org/obo/GO_0060284 regulation of cell development http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. http://purl.obolibrary.org/obo/UBERON_0003288 meninx of midbrain http://purl.obolibrary.org/obo/UBERON_0003547 brain meninx A meninx that is part of a midbrain [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003289 meninx of telencephalon http://purl.obolibrary.org/obo/UBERON_0003548 forebrain meninges A meninx that is part of a telencephalon [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060319 primitive erythrocyte differentiation http://purl.obolibrary.org/obo/GO_0030218 erythrocyte differentiation Erythrocyte differentiation which occurs as part of the process of primitive hemopoiesis. http://purl.obolibrary.org/obo/UBERON_0003290 meninx of diencephalon http://purl.obolibrary.org/obo/UBERON_0003548 forebrain meninges A meninx that is part of a diencephalon [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060341 regulation of cellular localization http://purl.obolibrary.org/obo/GO_0032879 regulation of localization Any process that modulates the frequency, rate or extent of a process in which a cell, a substance, or a cellular entity is transported to, or maintained in a specific location within or in the membrane of a cell. http://purl.obolibrary.org/obo/UBERON_0003291 meninx of hindbrain http://purl.obolibrary.org/obo/UBERON_0003547 brain meninx A meninx that is part of a hindbrain [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060491 regulation of cell projection assembly http://purl.obolibrary.org/obo/GO_0031344 regulation of cell projection organization Any process that modulates the rate, frequency, or extent of cell projection assembly. http://purl.obolibrary.org/obo/UBERON_0003294 gland of foregut http://purl.obolibrary.org/obo/UBERON_0003408 gland of digestive tract A gland that is part of a foregut [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003295 pharyngeal gland http://purl.obolibrary.org/obo/UBERON_0036225 respiratory system gland Racemose mucous glands beneath the mucous membrane of the pharynx. http://purl.obolibrary.org/obo/GO_0060537 muscle tissue development http://purl.obolibrary.org/obo/GO_0009888 tissue development The progression of muscle tissue over time, from its initial formation to its mature state. Muscle tissue is a contractile tissue made up of actin and myosin fibers. http://purl.obolibrary.org/obo/UBERON_0003296 gland of diencephalon http://purl.obolibrary.org/obo/UBERON_0002530 gland Any gland that is part of the diencephalon. Examples: pineal gland, neurohypophysis. http://purl.obolibrary.org/obo/GO_0060627 regulation of vesicle-mediated transport http://purl.obolibrary.org/obo/GO_0051049 regulation of transport Any process that modulates the rate, frequency, or extent of vesicle-mediated transport, the directed movement of substances, either within a vesicle or in the vesicle membrane, into, out of or within a cell. http://purl.obolibrary.org/obo/UBERON_0003297 gland of integumental system http://purl.obolibrary.org/obo/UBERON_0002530 gland A gland that is part of a integumental system [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0061515 myeloid cell development http://purl.obolibrary.org/obo/GO_0030097 hemopoiesis The process whose specific outcome is the progression of a myeloid cell over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/UBERON_0003299 roof plate of midbrain http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue The mesencephalic roof plate, including the caudal and rostral part of the midbrain roof. http://purl.obolibrary.org/obo/GO_0061526 acetylcholine secretion http://purl.obolibrary.org/obo/GO_0015870 acetylcholine transport The regulated release of acetylcholine by a cell. http://purl.obolibrary.org/obo/UBERON_0003300 roof plate of telencephalon http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue A roof plate that is part of a telencephalon [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0061687 detoxification of inorganic compound http://purl.obolibrary.org/obo/GO_0098754 detoxification Any process that reduces or removes the toxicity of inorganic compounds. These include transport of such compounds away from sensitive areas and to compartments or complexes whose purpose is sequestration of inorganic compounds. http://purl.obolibrary.org/obo/UBERON_0003301 roof plate of diencephalon http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue A roof plate that is part of a diencephalon [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0065009 regulation of molecular function http://purl.obolibrary.org/obo/GO_0065007 biological regulation Any process that modulates the frequency, rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding. http://purl.obolibrary.org/obo/UBERON_0003302 roof plate of metencephalon http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue A roof plate that is part of a metencephalon [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003303 roof plate of medulla oblongata http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue A roof plate that is part of a medulla oblongata [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0070131 positive regulation of mitochondrial translation http://purl.obolibrary.org/obo/GO_0070129 regulation of mitochondrial translation Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion. http://purl.obolibrary.org/obo/UBERON_0003304 mesoderm blood island http://purl.obolibrary.org/obo/UBERON_0012275 meso-epithelium A blood island that is part of a mesoderm. http://purl.obolibrary.org/obo/GO_0070507 regulation of microtubule cytoskeleton organization http://purl.obolibrary.org/obo/GO_0032886 regulation of microtubule-based process Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins. http://purl.obolibrary.org/obo/UBERON_0003306 floor plate of neural tube http://purl.obolibrary.org/obo/UBERON_0000481 multi-tissue structure A floor plate that is part of a neural tube [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0070613 regulation of protein processing http://purl.obolibrary.org/obo/GO_1903317 regulation of protein maturation Any process that modulates the frequency, rate or extent of protein processing, a protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein. http://purl.obolibrary.org/obo/UBERON_0003307 floor plate of midbrain http://purl.obolibrary.org/obo/UBERON_0003306 floor plate of neural tube A floor plate that is part of a midbrain [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0071322 cellular response to carbohydrate stimulus http://purl.obolibrary.org/obo/GO_0009743 response to carbohydrate Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbohydrate stimulus. http://purl.obolibrary.org/obo/UBERON_0003308 floor plate of telencephalon http://purl.obolibrary.org/obo/UBERON_0003306 floor plate of neural tube A floor plate that is part of a telencephalon [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0071331 cellular response to hexose stimulus http://purl.obolibrary.org/obo/GO_0071326 cellular response to monosaccharide stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hexose stimulus. http://purl.obolibrary.org/obo/UBERON_0003309 floor plate of diencephalon http://purl.obolibrary.org/obo/UBERON_0003306 floor plate of neural tube A floor plate that is part of a diencephalon [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003310 floor plate of metencephalon http://purl.obolibrary.org/obo/UBERON_0003306 floor plate of neural tube A floor plate that is part of a metencephalon [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0071333 cellular response to glucose stimulus http://purl.obolibrary.org/obo/GO_0071331 cellular response to hexose stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus. http://purl.obolibrary.org/obo/UBERON_0003311 floor plate of medulla oblongata http://purl.obolibrary.org/obo/UBERON_0003306 floor plate of neural tube A floor plate that is part of a medulla oblongata [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0071622 regulation of granulocyte chemotaxis http://purl.obolibrary.org/obo/GO_0002688 regulation of leukocyte chemotaxis Any process that modulates the rate, frequency or extent of granulocyte chemotaxis. Granulocyte chemotaxis is the movement of a granulocyte in response to an external stimulus. http://purl.obolibrary.org/obo/UBERON_0003312 mesenchyme of testis http://purl.obolibrary.org/obo/UBERON_0003855 gonad mesenchyme Mesenchyme that is part of a developing testis [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003314 eye mesenchyme http://purl.obolibrary.org/obo/UBERON_0009891 facial mesenchyme Mesenchyme that is part of a developing camera-type eye. http://purl.obolibrary.org/obo/GO_0071675 regulation of mononuclear cell migration http://purl.obolibrary.org/obo/GO_0002685 regulation of leukocyte migration Any process that modulates the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body. http://purl.obolibrary.org/obo/GO_0071806 protein transmembrane transport http://purl.obolibrary.org/obo/GO_0055085 transmembrane transport The process in which a protein is transported across a membrane. http://purl.obolibrary.org/obo/UBERON_0003315 mesenchyme of ovary http://purl.obolibrary.org/obo/UBERON_0003855 gonad mesenchyme Mesenchyme that is part of a developing ovary [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003316 mesenchyme of yolk sac http://purl.obolibrary.org/obo/UBERON_0010333 extraembryonic membrane mesenchyme The portion of the yolk sac that is derived from mesoderm and consists of mesenchyme. http://purl.obolibrary.org/obo/GO_0071840 cellular component organization or biogenesis http://purl.obolibrary.org/obo/GO_0009987 cellular process A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellular component. http://purl.obolibrary.org/obo/GO_0071941 nitrogen cycle metabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process A nitrogen compound metabolic process that contributes to the nitrogen cycle. The nitrogen cycle is a series of metabolic pathways by which nitrogen is converted between various forms and redox states; it encompasses pathways in which nitrogen is acted upon directly, such as nitrification, denitrification, nitrogen fixation, and mineralization. http://purl.obolibrary.org/obo/UBERON_0003318 mesenchyme of elbow http://purl.obolibrary.org/obo/UBERON_0003859 forelimb mesenchyme Mesenchyme that is part of a developing elbow [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003319 mesenchyme of carpal region http://purl.obolibrary.org/obo/UBERON_0003859 forelimb mesenchyme Mesenchyme of the carpal region that contributes to the carpal skeleton. http://purl.obolibrary.org/obo/GO_0072337 modified amino acid transport http://purl.obolibrary.org/obo/GO_0071705 nitrogen compound transport The directed movement of modified amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/UBERON_0003320 mesenchyme of hip http://purl.obolibrary.org/obo/UBERON_0003104 mesenchyme Mesenchyme that is part of a developing hip [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003321 mesenchyme of knee http://purl.obolibrary.org/obo/UBERON_0003860 hindlimb mesenchyme Mesenchyme that is part of a developing knee [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072488 ammonium transmembrane transport http://purl.obolibrary.org/obo/GO_0071705 nitrogen compound transport The process in which ammonium is transported across a membrane. Ammonium is the cation NH4+. http://purl.obolibrary.org/obo/GO_0072530 purine-containing compound transmembrane transport http://purl.obolibrary.org/obo/GO_0071705 nitrogen compound transport The process in which a purine-containing compound is transported across a membrane. A purine-containing compound is any compound that contains purine or a formal derivative thereof. http://purl.obolibrary.org/obo/UBERON_0003322 mesenchyme of shoulder http://purl.obolibrary.org/obo/UBERON_0003104 mesenchyme Mesenchyme that is part of a developing shoulder [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003323 mesenchyme of upper jaw http://purl.obolibrary.org/obo/UBERON_0034995 jaw mesenchyme Mesenchyme that is part of a developing upper jaw [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072678 T cell migration http://purl.obolibrary.org/obo/GO_0072676 lymphocyte migration The movement of a T cell within or between different tissues and organs of the body. http://purl.obolibrary.org/obo/UBERON_0003324 mesenchyme of lower jaw http://purl.obolibrary.org/obo/UBERON_0034995 jaw mesenchyme Mesenchyme that is part of a developing lower jaw [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0080134 regulation of response to stress http://purl.obolibrary.org/obo/GO_0048583 regulation of response to stimulus Any process that modulates the frequency, rate or extent of a response to stress. Response to stress is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). http://purl.obolibrary.org/obo/UBERON_0003325 mesenchyme of pinna http://purl.obolibrary.org/obo/UBERON_0005253 head mesenchyme Mesenchyme that is part of a developing pinna [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003326 mesenchyme of mammary gland http://purl.obolibrary.org/obo/UBERON_0003104 mesenchyme Mesenchyme that is part of a developing mammary gland. http://purl.obolibrary.org/obo/GO_0085029 extracellular matrix assembly http://purl.obolibrary.org/obo/GO_0030198 extracellular matrix organization The aggregation, arrangement and bonding together of the extracellular matrix. http://purl.obolibrary.org/obo/UBERON_0003327 mesenchyme of forearm http://purl.obolibrary.org/obo/UBERON_0003859 forelimb mesenchyme Mesenchyme that is part of a developing lower arm [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0090032 negative regulation of steroid hormone biosynthetic process http://purl.obolibrary.org/obo/GO_0010894 negative regulation of steroid biosynthetic process Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroid hormones,compounds with a 1, 2, cyclopentanoperhydrophenanthrene nucleus that act as hormones. http://purl.obolibrary.org/obo/UBERON_0003328 mesenchyme of footplate http://purl.obolibrary.org/obo/UBERON_0010377 mesenchyme from somatopleure Mesenchyme that is part of a footplate. http://purl.obolibrary.org/obo/GO_0090068 positive regulation of cell cycle process http://purl.obolibrary.org/obo/GO_0045787 positive regulation of cell cycle Any process that increases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. http://purl.obolibrary.org/obo/UBERON_0003329 submucosa of anal canal http://purl.obolibrary.org/obo/UBERON_0001208 submucosa of large intestine A submucosa that is part of an anal canal [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003330 submucosa of rectum http://purl.obolibrary.org/obo/UBERON_0001208 submucosa of large intestine The submucous layer of the wall of the rectum. http://purl.obolibrary.org/obo/GO_0090077 foam cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions. http://purl.obolibrary.org/obo/UBERON_0003331 submucosa of colon http://purl.obolibrary.org/obo/UBERON_0001208 submucosa of large intestine A submucosa that is part of a colon [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0090132 epithelium migration http://purl.obolibrary.org/obo/GO_0090130 tissue migration The process in which the population of cells that make up an epithelium undergo directed movement. http://purl.obolibrary.org/obo/UBERON_0003332 submucosa of duodenum http://purl.obolibrary.org/obo/UBERON_0001205 submucosa of small intestine A submucosa that is part of a duodenum [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0097305 response to alcohol http://purl.obolibrary.org/obo/GO_1901700 response to oxygen-containing compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alcohol stimulus. http://purl.obolibrary.org/obo/UBERON_0003333 submucosa of jejunum http://purl.obolibrary.org/obo/UBERON_0001205 submucosa of small intestine A submucosa that is part of a jejunum [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0098590 plasma membrane region http://purl.obolibrary.org/obo/GO_0016020 membrane A membrane that is a (regional) part of the plasma membrane. http://purl.obolibrary.org/obo/UBERON_0003334 serosa of rectum http://purl.obolibrary.org/obo/UBERON_0001209 serosa of large intestine A serous membrane that is part of a rectum [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0098609 cell-cell adhesion http://purl.obolibrary.org/obo/GO_0007155 cell adhesion The attachment of one cell to another cell via adhesion molecules. http://purl.obolibrary.org/obo/UBERON_0003335 serosa of colon http://purl.obolibrary.org/obo/UBERON_0001209 serosa of large intestine A serous membrane that is part of a colon [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0098636 protein complex involved in cell adhesion http://purl.obolibrary.org/obo/GO_0032991 protein-containing complex Any protein complex that is capable of carrying out some part of the process of cell adhesion to the cell matrix or to another cell. http://purl.obolibrary.org/obo/UBERON_0003336 serosa of duodenum http://purl.obolibrary.org/obo/UBERON_0001206 serosa of small intestine A serous membrane that is part of a duodenum [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0098655 monoatomic cation transmembrane transport http://purl.obolibrary.org/obo/GO_0034220 monoatomic ion transmembrane transport The process in which a monoatomic cation is transported across a membrane. Monatomic cations (also called simple cations) are positively charged ions consisting of exactly one atom. http://purl.obolibrary.org/obo/UBERON_0003337 serosa of jejunum http://purl.obolibrary.org/obo/UBERON_0001206 serosa of small intestine A serous membrane that is part of a jejunum [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0098722 asymmetric stem cell division http://purl.obolibrary.org/obo/GO_0017145 stem cell division Division of a stem cell during which it retains its identity and buds off a daughter cell with a new identity. http://purl.obolibrary.org/obo/UBERON_0003338 ganglion of peripheral nervous system http://purl.obolibrary.org/obo/UBERON_0000045 ganglion A spatially aggregated collection of nerve cell bodies in the PNS, consisting of one or more subpopulations that share cell type, chemical phenotype, and connections. (CUMBO). http://purl.obolibrary.org/obo/GO_0098727 maintenance of cell number http://purl.obolibrary.org/obo/GO_0032502 developmental process Any process by which the numbers of cells of a particular type or in a tissue are maintained. http://purl.obolibrary.org/obo/UBERON_0003339 ganglion of central nervous system http://purl.obolibrary.org/obo/UBERON_0000045 ganglion A ganglion that is part of a central nervous system [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0098754 detoxification http://purl.obolibrary.org/obo/GO_0008150 biological_process Any process that reduces or removes the toxicity of a toxic substance. These may include transport of the toxic substance away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance. http://purl.obolibrary.org/obo/UBERON_0003342 mucosa of anal canal http://purl.obolibrary.org/obo/UBERON_0001207 mucosa of large intestine A mucosa that is part of an anal canal [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003343 mucosa of oral region http://purl.obolibrary.org/obo/UBERON_0003729 mouth mucosa A mucosa that is part of a oral opening [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0098815 modulation of excitatory postsynaptic potential http://purl.obolibrary.org/obo/GO_0050804 modulation of chemical synaptic transmission Any process that modulates the frequency, rate or extent of excitatory postsynaptic potential (EPSP). EPSP is a process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential. http://purl.obolibrary.org/obo/UBERON_0003346 mucosa of rectum http://purl.obolibrary.org/obo/UBERON_0001207 mucosa of large intestine A mucosa that is part of a rectum [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003350 epithelium of mucosa http://purl.obolibrary.org/obo/UBERON_0000483 epithelium A layer of epithelial cells on the surface of the mucosa. http://purl.obolibrary.org/obo/GO_0098878 neurotransmitter receptor complex http://purl.obolibrary.org/obo/GO_0098802 plasma membrane signaling receptor complex Any protein complex that is capable of functioning as a neurotransmitter receptor. http://purl.obolibrary.org/obo/UBERON_0003351 pharyngeal epithelium http://purl.obolibrary.org/obo/UBERON_0005911 endo-epithelium An epithelium that is part of a pharynx [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0098900 regulation of action potential http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels. http://purl.obolibrary.org/obo/UBERON_0003352 epithelium of midgut http://purl.obolibrary.org/obo/UBERON_0003929 digestive tract epithelium An epithelium that is part of a midgut. http://purl.obolibrary.org/obo/GO_0099003 vesicle-mediated transport in synapse http://purl.obolibrary.org/obo/GO_0016192 vesicle-mediated transport Any vesicle-mediated transport that occurs in a synapse. http://purl.obolibrary.org/obo/UBERON_0003353 epithelium of hindgut http://purl.obolibrary.org/obo/UBERON_0003929 digestive tract epithelium An epithelium that is part of a hindgut [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0099111 microtubule-based transport http://purl.obolibrary.org/obo/GO_0006810 transport A microtubule-based process that results in the transport of organelles, other microtubules, or other cellular components. Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules. http://purl.obolibrary.org/obo/UBERON_0003354 epithelium of rectum http://purl.obolibrary.org/obo/UBERON_0016885 epithelium of terminal part of digestive tract An epithelium that is part of a rectum [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0099504 synaptic vesicle cycle http://purl.obolibrary.org/obo/GO_0099003 vesicle-mediated transport in synapse A biological process in which synaptic vesicles are loaded with neurotransmitters, move to the active zone, exocytose and are then recycled via endocytosis, ultimately leading to reloading with neurotransmitters. http://purl.obolibrary.org/obo/UBERON_0003357 epithelium of tongue http://purl.obolibrary.org/obo/UBERON_0019304 sensory organ epithelium An epithelium that is part of a tongue [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003359 epithelium of submandibular gland http://purl.obolibrary.org/obo/UBERON_0004809 salivary gland epithelium An epithelium that is part of a submandibular gland [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0099528 G protein-coupled neurotransmitter receptor activity http://purl.obolibrary.org/obo/GO_0004930 G protein-coupled receptor activity Combining with a neurotransmitter and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. http://purl.obolibrary.org/obo/UBERON_0003360 epithelium of parotid gland http://purl.obolibrary.org/obo/UBERON_0004809 salivary gland epithelium An epithelium that is part of a parotid gland [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003361 epithelium of sublingual gland http://purl.obolibrary.org/obo/UBERON_0004809 salivary gland epithelium An epithelium that is part of a sublingual gland [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0099604 ligand-gated calcium channel activity http://purl.obolibrary.org/obo/GO_0099094 ligand-gated monoatomic cation channel activity Enables the transmembrane transfer of a calcium ions by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts. http://purl.obolibrary.org/obo/UBERON_0003364 epithelium of right lung http://purl.obolibrary.org/obo/UBERON_0000115 lung epithelium An epithelium that is part of a right lung [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0100001 regulation of skeletal muscle contraction by action potential http://purl.obolibrary.org/obo/GO_0014819 regulation of skeletal muscle contraction Any action potential process that regulates skeletal muscle contraction. http://purl.obolibrary.org/obo/GO_1901264 carbohydrate derivative transport http://purl.obolibrary.org/obo/GO_0006810 transport The directed movement of a carbohydrate derivative into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/UBERON_0003365 epithelium of left lung http://purl.obolibrary.org/obo/UBERON_0000115 lung epithelium An epithelium that is part of a left lung [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003367 epithelium of vomeronasal organ http://purl.obolibrary.org/obo/UBERON_0019306 nose epithelium An epithelium that is part of a vomeronasal organ [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_1901292 nucleoside phosphate catabolic process http://purl.obolibrary.org/obo/GO_0046434 organophosphate catabolic process The chemical reactions and pathways resulting in the breakdown of a nucleoside phosphate. http://purl.obolibrary.org/obo/UBERON_0003371 pelvic appendage bud ectoderm http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue An unilaminar epithelium that surrounds a pelvic appendage bud. http://purl.obolibrary.org/obo/GO_1901293 nucleoside phosphate biosynthetic process http://purl.obolibrary.org/obo/GO_0034654 nucleobase-containing compound biosynthetic process The chemical reactions and pathways resulting in the formation of a nucleoside phosphate. http://purl.obolibrary.org/obo/UBERON_0003372 pectoral appendage bud ectoderm http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue An unilaminar epithelium that surrounds a pectoral appendage bud. http://purl.obolibrary.org/obo/UBERON_0003373 ectoderm of footplate http://purl.obolibrary.org/obo/UBERON_0000924 ectoderm An ectoderm that is part of a footplate. http://purl.obolibrary.org/obo/GO_1901374 acetate ester transport http://purl.obolibrary.org/obo/GO_0006810 transport The directed movement of an acetate ester into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/UBERON_0003374 chorionic ectoderm http://purl.obolibrary.org/obo/UBERON_0000478 extraembryonic structure An extraembryonic structure that develops_from a ectoderm and is part of a chorion. http://purl.obolibrary.org/obo/GO_1901385 regulation of voltage-gated calcium channel activity http://purl.obolibrary.org/obo/GO_0022898 regulation of transmembrane transporter activity Any process that modulates the frequency, rate or extent of voltage-gated calcium channel activity. http://purl.obolibrary.org/obo/UBERON_0003379 cardiac muscle of right atrium http://purl.obolibrary.org/obo/UBERON_0004490 cardiac muscle tissue of atrium A portion of cardiac muscle tissue that is part of a right atrium [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_1901419 regulation of response to alcohol http://purl.obolibrary.org/obo/GO_0048583 regulation of response to stimulus Any process that modulates the frequency, rate or extent of response to alcohol. http://purl.obolibrary.org/obo/UBERON_0003380 cardiac muscle of left atrium http://purl.obolibrary.org/obo/UBERON_0004490 cardiac muscle tissue of atrium A portion of cardiac muscle tissue that is part of a left atrium [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_1901420 negative regulation of response to alcohol http://purl.obolibrary.org/obo/GO_1901419 regulation of response to alcohol Any process that stops, prevents or reduces the frequency, rate or extent of response to alcohol. http://purl.obolibrary.org/obo/UBERON_0003381 cardiac muscle of right ventricle http://purl.obolibrary.org/obo/UBERON_0018649 cardiac muscle tissue of ventricle A portion of cardiac muscle tissue that is part of a right ventricle [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_1901421 positive regulation of response to alcohol http://purl.obolibrary.org/obo/GO_1901419 regulation of response to alcohol Any process that activates or increases the frequency, rate or extent of response to alcohol. http://purl.obolibrary.org/obo/UBERON_0003382 cardiac muscle of left ventricle http://purl.obolibrary.org/obo/UBERON_0018649 cardiac muscle tissue of ventricle A portion of cardiac muscle tissue that is part of a left ventricle [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_1901623 regulation of lymphocyte chemotaxis http://purl.obolibrary.org/obo/GO_2000401 regulation of lymphocyte migration Any process that modulates the frequency, rate or extent of lymphocyte chemotaxis. http://purl.obolibrary.org/obo/UBERON_0003383 cardiac muscle tissue of interventricular septum http://purl.obolibrary.org/obo/UBERON_0004667 interventricular septum muscular part A portion of cardiac muscle tissue that is part of an interventricular septum [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_1901679 nucleotide transmembrane transport http://purl.obolibrary.org/obo/GO_0055085 transmembrane transport The directed movement of nucleotide across a membrane. http://purl.obolibrary.org/obo/UBERON_0003384 skeletal muscle tissue of pharynx http://purl.obolibrary.org/obo/UBERON_0004830 respiratory system skeletal muscle A portion of skeletal muscle tissue that is part of a pharynx [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_1901698 response to nitrogen compound http://purl.obolibrary.org/obo/GO_0042221 response to chemical Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen compound stimulus. http://purl.obolibrary.org/obo/UBERON_0003386 smooth muscle of eye http://purl.obolibrary.org/obo/UBERON_0001135 smooth muscle tissue Any of the striated muscles that move the eye and include: superior rectus, inferior rectus, medial rectus, lateral rectus, superior oblique, inferior oblique, retractor bulbi. http://purl.obolibrary.org/obo/GO_1901861 regulation of muscle tissue development http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of muscle tissue development. http://purl.obolibrary.org/obo/UBERON_0003387 smooth muscle of trachea http://purl.obolibrary.org/obo/UBERON_0004233 lower respiratory tract smooth muscle A portion of smooth muscle tissue that is part of a trachea [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_1902115 regulation of organelle assembly http://purl.obolibrary.org/obo/GO_0033043 regulation of organelle organization Any process that modulates the frequency, rate or extent of organelle assembly. http://purl.obolibrary.org/obo/UBERON_0003388 mesothelium of pericardial cavity http://purl.obolibrary.org/obo/UBERON_0001136 mesothelium A mesothelium that is part of a pericardium [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_1902116 negative regulation of organelle assembly http://purl.obolibrary.org/obo/GO_1902115 regulation of organelle assembly Any process that stops, prevents or reduces the frequency, rate or extent of organelle assembly. http://purl.obolibrary.org/obo/UBERON_0003389 mesothelium of diaphragm http://purl.obolibrary.org/obo/UBERON_0004807 respiratory system epithelium A mesothelium that is part of a diaphragm [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_1902117 positive regulation of organelle assembly http://purl.obolibrary.org/obo/GO_1902115 regulation of organelle assembly Any process that activates or increases the frequency, rate or extent of organelle assembly. http://purl.obolibrary.org/obo/UBERON_0003390 mesothelium of pleural cavity http://purl.obolibrary.org/obo/UBERON_0001136 mesothelium A mesothelium that is part of a pleural cavity [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_1902475 L-alpha-amino acid transmembrane transport http://purl.obolibrary.org/obo/GO_0015807 L-amino acid transport The directed movement of L-alpha-amino acid across a membrane by means of some agent such as a transporter or a pore. http://purl.obolibrary.org/obo/UBERON_0003393 mesentery of urinary system http://purl.obolibrary.org/obo/UBERON_0002095 mesentery A mesentery that is part of a urinary system [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_1902495 transmembrane transporter complex http://purl.obolibrary.org/obo/GO_1990351 transporter complex A transmembrane protein complex which enables the transfer of a substance from one side of a membrane to the other. http://purl.obolibrary.org/obo/UBERON_0003394 mesentery of hindgut http://purl.obolibrary.org/obo/UBERON_0002095 mesentery A mesentery that is part of a hindgut [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003395 mesentery of rectum http://purl.obolibrary.org/obo/UBERON_0004854 gastrointestinal system mesentery A mesentery that is part of a rectum [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_1902531 regulation of intracellular signal transduction http://purl.obolibrary.org/obo/GO_0009966 regulation of signal transduction Any process that modulates the frequency, rate or extent of intracellular signal transduction. http://purl.obolibrary.org/obo/UBERON_0003396 mesentery of colon http://purl.obolibrary.org/obo/UBERON_0007826 peritoneal mesentery A mesentery that is part of a colon [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_1902532 negative regulation of intracellular signal transduction http://purl.obolibrary.org/obo/GO_1902531 regulation of intracellular signal transduction Any process that stops, prevents or reduces the frequency, rate or extent of intracellular signal transduction. http://purl.obolibrary.org/obo/UBERON_0003397 mesentery of duodenum http://purl.obolibrary.org/obo/UBERON_0003336 serosa of duodenum A mesentery that is part of a duodenum [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_1902533 positive regulation of intracellular signal transduction http://purl.obolibrary.org/obo/GO_1902531 regulation of intracellular signal transduction Any process that activates or increases the frequency, rate or extent of intracellular signal transduction. http://purl.obolibrary.org/obo/UBERON_0003398 mesentery of jejunum http://purl.obolibrary.org/obo/UBERON_0003337 serosa of jejunum A mesentery that is part of a jejunum [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_1902600 proton transmembrane transport http://purl.obolibrary.org/obo/GO_0098655 monoatomic cation transmembrane transport The directed movement of a proton across a membrane. http://purl.obolibrary.org/obo/UBERON_0003403 skin of forearm http://purl.obolibrary.org/obo/UBERON_0002427 arm skin A zone of skin that is part of a lower arm [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_1902730 positive regulation of proteoglycan biosynthetic process http://purl.obolibrary.org/obo/GO_0010560 positive regulation of glycoprotein biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans. http://purl.obolibrary.org/obo/UBERON_0003404 lobar bronchus of right lung http://purl.obolibrary.org/obo/UBERON_0002183 lobar bronchus A lobar bronchus that is part of a right lung [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_1902930 regulation of alcohol biosynthetic process http://purl.obolibrary.org/obo/GO_0009889 regulation of biosynthetic process Any process that modulates the frequency, rate or extent of alcohol biosynthetic process. http://purl.obolibrary.org/obo/UBERON_0003405 lobar bronchus of left lung http://purl.obolibrary.org/obo/UBERON_0002183 lobar bronchus A lobar bronchus that is part of a left lung [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_1902931 negative regulation of alcohol biosynthetic process http://purl.obolibrary.org/obo/GO_1902930 regulation of alcohol biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of alcohol biosynthetic process. http://purl.obolibrary.org/obo/UBERON_0003406 cartilage of respiratory system http://purl.obolibrary.org/obo/UBERON_0007844 cartilage element A cartilage element that is part of a respiratory system [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_1902932 positive regulation of alcohol biosynthetic process http://purl.obolibrary.org/obo/GO_1902930 regulation of alcohol biosynthetic process Any process that activates or increases the frequency, rate or extent of alcohol biosynthetic process. http://purl.obolibrary.org/obo/UBERON_0003408 gland of digestive tract http://purl.obolibrary.org/obo/UBERON_0013765 digestive system element A gland that is part of a digestive tract [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_1903018 regulation of glycoprotein metabolic process http://purl.obolibrary.org/obo/GO_0051246 regulation of protein metabolic process Any process that modulates the frequency, rate or extent of glycoprotein metabolic process. http://purl.obolibrary.org/obo/UBERON_0003409 gland of tongue http://purl.obolibrary.org/obo/UBERON_0010047 oral gland Any of the mucous, serous, or mixed glands that empty their secretions onto the surface of the tongue. http://purl.obolibrary.org/obo/GO_1903019 negative regulation of glycoprotein metabolic process http://purl.obolibrary.org/obo/GO_1903018 regulation of glycoprotein metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of glycoprotein metabolic process. http://purl.obolibrary.org/obo/UBERON_0003412 pelvic appendage bud mesenchyme http://purl.obolibrary.org/obo/UBERON_0010329 paired limb/fin bud mesenchyme Mesenchyme that is part of a pelvic appendage bud. http://purl.obolibrary.org/obo/GO_1903020 positive regulation of glycoprotein metabolic process http://purl.obolibrary.org/obo/GO_1903018 regulation of glycoprotein metabolic process Any process that activates or increases the frequency, rate or extent of glycoprotein metabolic process. http://purl.obolibrary.org/obo/UBERON_0003413 pectoral appendage bud mesenchyme http://purl.obolibrary.org/obo/UBERON_0010329 paired limb/fin bud mesenchyme Mesenchyme that is part of a pectoral appendage bud. http://purl.obolibrary.org/obo/GO_1903305 regulation of regulated secretory pathway http://purl.obolibrary.org/obo/GO_0017157 regulation of exocytosis Any process that modulates the frequency, rate or extent of regulated secretory pathway. http://purl.obolibrary.org/obo/UBERON_0003416 mesenchyme of tongue http://purl.obolibrary.org/obo/UBERON_0003104 mesenchyme Mesenchyme that is part of a developing tongue [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_1903318 negative regulation of protein maturation http://purl.obolibrary.org/obo/GO_1903317 regulation of protein maturation Any process that stops, prevents or reduces the frequency, rate or extent of protein maturation. http://purl.obolibrary.org/obo/UBERON_0003418 mesenchyme of submandibular gland http://purl.obolibrary.org/obo/UBERON_0003324 mesenchyme of lower jaw Mesenchyme that is part of a developing submandibular gland [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_1903319 positive regulation of protein maturation http://purl.obolibrary.org/obo/GO_1903317 regulation of protein maturation Any process that activates or increases the frequency, rate or extent of protein maturation. http://purl.obolibrary.org/obo/UBERON_0003419 mesenchyme of parotid http://purl.obolibrary.org/obo/UBERON_0009891 facial mesenchyme Mesenchyme that is part of a developing parotid gland [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_1903426 regulation of reactive oxygen species biosynthetic process http://purl.obolibrary.org/obo/GO_2000377 regulation of reactive oxygen species metabolic process Any process that modulates the frequency, rate or extent of reactive oxygen species biosynthetic process. http://purl.obolibrary.org/obo/UBERON_0003420 mesenchyme of sublingual gland http://purl.obolibrary.org/obo/UBERON_0003104 mesenchyme Mesenchyme that is part of a developing sublingual gland [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_1903427 negative regulation of reactive oxygen species biosynthetic process http://purl.obolibrary.org/obo/GO_2000378 negative regulation of reactive oxygen species metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of reactive oxygen species biosynthetic process. http://purl.obolibrary.org/obo/UBERON_0003421 mesenchyme of vomeronasal organ http://purl.obolibrary.org/obo/UBERON_0009891 facial mesenchyme Mesenchyme that is part of a developing vomeronasal organ [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_1903428 positive regulation of reactive oxygen species biosynthetic process http://purl.obolibrary.org/obo/GO_2000379 positive regulation of reactive oxygen species metabolic process Any process that activates or increases the frequency, rate or extent of reactive oxygen species biosynthetic process. http://purl.obolibrary.org/obo/UBERON_0003422 mesenchyme of umbilical cord http://purl.obolibrary.org/obo/UBERON_0005292 extraembryonic tissue A gelatinous substance within the umbilical cord, largely made up of mucopolysaccharides (hyaluronic acid and chondroitin sulfate). It also contains some fibroblasts and macrophages. It is derived from Extra Embryonic Mesoderm[WP]. http://purl.obolibrary.org/obo/GO_1903430 negative regulation of cell maturation http://purl.obolibrary.org/obo/GO_0010721 negative regulation of cell development Any process that stops, prevents or reduces the frequency, rate or extent of cell maturation. http://purl.obolibrary.org/obo/UBERON_0003425 renal lymph node http://purl.obolibrary.org/obo/UBERON_0000029 lymph node A lymph node that is located in a kidney [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_1903431 positive regulation of cell maturation http://purl.obolibrary.org/obo/GO_0010720 positive regulation of cell development Any process that activates or increases the frequency, rate or extent of cell maturation. http://purl.obolibrary.org/obo/UBERON_0003426 dermis adipose tissue http://purl.obolibrary.org/obo/UBERON_0003585 dermis connective tissue An adipose tissue that is part of a dermis [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_1903828 negative regulation of protein localization http://purl.obolibrary.org/obo/GO_0032880 regulation of protein localization Any process that stops, prevents or reduces the frequency, rate or extent of a protein localization. http://purl.obolibrary.org/obo/UBERON_0003429 abdomen nerve http://purl.obolibrary.org/obo/UBERON_0003825 nerve of abdominal segment A nerve that is part of an abdomen [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_1904062 regulation of monoatomic cation transmembrane transport http://purl.obolibrary.org/obo/GO_0034765 regulation of monoatomic ion transmembrane transport Any process that modulates the frequency, rate or extent of cation transmembrane transport. http://purl.obolibrary.org/obo/UBERON_0003430 neck nerve http://purl.obolibrary.org/obo/UBERON_0001021 nerve A nerve that is part of a neck [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_1904396 regulation of neuromuscular junction development http://purl.obolibrary.org/obo/GO_0050807 regulation of synapse organization Any process that modulates the frequency, rate or extent of neuromuscular junction development. http://purl.obolibrary.org/obo/UBERON_0003431 leg nerve http://purl.obolibrary.org/obo/UBERON_0003442 hindlimb nerve A nerve that is part of a leg [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_1904680 peptide transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity Enables the transfer of a peptide from one side of a membrane to the other. http://purl.obolibrary.org/obo/UBERON_0003432 chest nerve http://purl.obolibrary.org/obo/UBERON_0003824 nerve of thoracic segment A nerve that is part of a chest [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_1904949 ATPase complex http://purl.obolibrary.org/obo/GO_1902494 catalytic complex A protein complex which is capable of ATPase activity. http://purl.obolibrary.org/obo/UBERON_0003433 arm nerve http://purl.obolibrary.org/obo/UBERON_0003441 forelimb nerve A nerve that is part of an arm [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_1905521 regulation of macrophage migration http://purl.obolibrary.org/obo/GO_0071675 regulation of mononuclear cell migration Any process that modulates the frequency, rate or extent of macrophage migration. http://purl.obolibrary.org/obo/UBERON_0003434 wrist nerve http://purl.obolibrary.org/obo/UBERON_0003448 manus nerve A nerve that is part of a wrist [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_1905522 negative regulation of macrophage migration http://purl.obolibrary.org/obo/GO_0071676 negative regulation of mononuclear cell migration Any process that stops, prevents or reduces the frequency, rate or extent of macrophage migration. http://purl.obolibrary.org/obo/UBERON_0003435 pedal digit nerve http://purl.obolibrary.org/obo/UBERON_0003445 pes nerve A nerve that is part of a toe [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_1905523 positive regulation of macrophage migration http://purl.obolibrary.org/obo/GO_0071677 positive regulation of mononuclear cell migration Any process that activates or increases the frequency, rate or extent of macrophage migration. http://purl.obolibrary.org/obo/UBERON_0003436 shoulder nerve http://purl.obolibrary.org/obo/UBERON_0001021 nerve A nerve that is part of a shoulder [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_1990822 basic amino acid transmembrane transport http://purl.obolibrary.org/obo/GO_0015802 basic amino acid transport The directed movement of basic amino acids from one side of a membrane to the other. http://purl.obolibrary.org/obo/UBERON_0003437 eyelid nerve http://purl.obolibrary.org/obo/UBERON_0001021 nerve A nerve that innervates an eyelid. http://purl.obolibrary.org/obo/GO_2000181 negative regulation of blood vessel morphogenesis http://purl.obolibrary.org/obo/GO_1901343 negative regulation of vasculature development Any process that stops, prevents, or reduces the frequency, rate or extent of blood vessel morphogenesis. http://purl.obolibrary.org/obo/UBERON_0003438 iris nerve http://purl.obolibrary.org/obo/UBERON_0001021 nerve Any nerve that innervates the iris. http://purl.obolibrary.org/obo/GO_2000191 regulation of fatty acid transport http://purl.obolibrary.org/obo/GO_0032890 regulation of organic acid transport Any process that modulates the frequency, rate or extent of fatty acid transport. http://purl.obolibrary.org/obo/UBERON_0003439 nerve of trunk region http://purl.obolibrary.org/obo/UBERON_0001021 nerve A nerve that is part of the trunk region of the body (not to be confused with a nerve trunk). http://purl.obolibrary.org/obo/GO_2000192 negative regulation of fatty acid transport http://purl.obolibrary.org/obo/GO_2000191 regulation of fatty acid transport Any process that stops, prevents, or reduces the frequency, rate or extent of fatty acid transport. http://purl.obolibrary.org/obo/UBERON_0003440 limb nerve http://purl.obolibrary.org/obo/UBERON_0001021 nerve A nerve that is part of a limb [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_2000193 positive regulation of fatty acid transport http://purl.obolibrary.org/obo/GO_2000191 regulation of fatty acid transport Any process that activates or increases the frequency, rate or extent of fatty acid transport. http://purl.obolibrary.org/obo/UBERON_0003441 forelimb nerve http://purl.obolibrary.org/obo/UBERON_0003440 limb nerve A nerve that is part of a forelimb [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_2000197 regulation of ribonucleoprotein complex localization http://purl.obolibrary.org/obo/GO_0060341 regulation of cellular localization Any process that modulates the frequency, rate or extent of ribonucleoprotein complex localization. http://purl.obolibrary.org/obo/UBERON_0003442 hindlimb nerve http://purl.obolibrary.org/obo/UBERON_0003440 limb nerve A nerve that is part of a hindlimb [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_2000241 regulation of reproductive process http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process Any process that modulates the frequency, rate or extent of reproductive process. http://purl.obolibrary.org/obo/UBERON_0003443 thoracic cavity nerve http://purl.obolibrary.org/obo/UBERON_0001021 nerve A nerve that is located in a thoracic cavity [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_2000242 negative regulation of reproductive process http://purl.obolibrary.org/obo/GO_2000241 regulation of reproductive process Any process that stops, prevents, or reduces the frequency, rate or extent of reproductive process. http://purl.obolibrary.org/obo/UBERON_0003444 pelvis nerve http://purl.obolibrary.org/obo/UBERON_0003825 nerve of abdominal segment A nerve that is part of a pelvis [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_2000243 positive regulation of reproductive process http://purl.obolibrary.org/obo/GO_2000241 regulation of reproductive process Any process that activates or increases the frequency, rate or extent of reproductive process. http://purl.obolibrary.org/obo/UBERON_0003445 pes nerve http://purl.obolibrary.org/obo/UBERON_0003442 hindlimb nerve A nerve that is part of a foot [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_2000300 regulation of synaptic vesicle exocytosis http://purl.obolibrary.org/obo/GO_1903305 regulation of regulated secretory pathway Any process that modulates the frequency, rate or extent of synaptic vesicle exocytosis. http://purl.obolibrary.org/obo/UBERON_0003446 ankle nerve http://purl.obolibrary.org/obo/UBERON_0003445 pes nerve A nerve that is part of an ankle [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_2000301 negative regulation of synaptic vesicle exocytosis http://purl.obolibrary.org/obo/GO_2000300 regulation of synaptic vesicle exocytosis Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle exocytosis. http://purl.obolibrary.org/obo/UBERON_0003447 digit nerve of manus http://purl.obolibrary.org/obo/UBERON_0003448 manus nerve A nerve that is part of a finger [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_2000302 positive regulation of synaptic vesicle exocytosis http://purl.obolibrary.org/obo/GO_2000300 regulation of synaptic vesicle exocytosis Any process that activates or increases the frequency, rate or extent of synaptic vesicle exocytosis. http://purl.obolibrary.org/obo/UBERON_0003448 manus nerve http://purl.obolibrary.org/obo/UBERON_0003441 forelimb nerve A nerve that is part of a manus [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_2000377 regulation of reactive oxygen species metabolic process http://purl.obolibrary.org/obo/GO_0019222 regulation of metabolic process Any process that modulates the frequency, rate or extent of reactive oxygen species metabolic process. http://purl.obolibrary.org/obo/UBERON_0003449 tail intervertebral disc http://purl.obolibrary.org/obo/UBERON_0001066 intervertebral disk An intervertebral disk that is part of a tail [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_2000378 negative regulation of reactive oxygen species metabolic process http://purl.obolibrary.org/obo/GO_2000377 regulation of reactive oxygen species metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of reactive oxygen species metabolic process. http://purl.obolibrary.org/obo/UBERON_0003452 trabecula carnea cardiac muscle tissue http://purl.obolibrary.org/obo/UBERON_0018649 cardiac muscle tissue of ventricle A portion of cardiac muscle tissue that is part of a trabecula carnea [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_2000379 positive regulation of reactive oxygen species metabolic process http://purl.obolibrary.org/obo/GO_2000377 regulation of reactive oxygen species metabolic process Any process that activates or increases the frequency, rate or extent of reactive oxygen species metabolic process. http://purl.obolibrary.org/obo/UBERON_0003453 large intestine Peyer's patch http://purl.obolibrary.org/obo/UBERON_0001211 Peyer's patch A Peyer's patch that is part of a large intestine. http://purl.obolibrary.org/obo/GO_2000404 regulation of T cell migration http://purl.obolibrary.org/obo/GO_2000401 regulation of lymphocyte migration Any process that modulates the frequency, rate or extent of T cell migration. http://purl.obolibrary.org/obo/UBERON_0003454 small intestine Peyer's patch http://purl.obolibrary.org/obo/UBERON_0001211 Peyer's patch Nodular lymphoid structures on the serosal surface of the small intestine. http://purl.obolibrary.org/obo/GO_2000406 positive regulation of T cell migration http://purl.obolibrary.org/obo/GO_2000404 regulation of T cell migration Any process that activates or increases the frequency, rate or extent of T cell migration. http://purl.obolibrary.org/obo/UBERON_0003455 inner renal medulla loop of Henle http://purl.obolibrary.org/obo/UBERON_0034997 renal medulla loop of Henle A loop of Henle that is part of a inner medulla of kidney [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_2000904 regulation of starch metabolic process http://purl.obolibrary.org/obo/GO_0032881 regulation of polysaccharide metabolic process Any process that modulates the frequency, rate or extent of starch metabolic process. http://purl.obolibrary.org/obo/UBERON_0003456 respiratory system lymphatic vessel http://purl.obolibrary.org/obo/UBERON_0001473 lymphatic vessel A lymphatic vessel that is part of a respiratory system [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0051938 L-glutamate import http://purl.obolibrary.org/obo/GO_0015807 L-amino acid transport The directed movement of L-glutamate, the L-enantiomer of the anion of 2-aminopentanedioic acid, into a cell or organelle. http://purl.obolibrary.org/obo/UBERON_0003457 head bone http://purl.obolibrary.org/obo/UBERON_0007914 bone of craniocervical region A bone that is part of a head [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0051966 regulation of synaptic transmission, glutamatergic http://purl.obolibrary.org/obo/GO_0050804 modulation of chemical synaptic transmission Any process that modulates the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate. http://purl.obolibrary.org/obo/UBERON_0003458 neck bone http://purl.obolibrary.org/obo/UBERON_0001474 bone element A bone that is part of a neck [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0051967 negative regulation of synaptic transmission, glutamatergic http://purl.obolibrary.org/obo/GO_0051966 regulation of synaptic transmission, glutamatergic Any process that stops, prevents, or reduces the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate. http://purl.obolibrary.org/obo/UBERON_0003459 chest bone http://purl.obolibrary.org/obo/UBERON_0005175 chest organ A bone that is part of a chest [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0051968 positive regulation of synaptic transmission, glutamatergic http://purl.obolibrary.org/obo/GO_0051966 regulation of synaptic transmission, glutamatergic Any process that activates, maintains or increases the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate. http://purl.obolibrary.org/obo/UBERON_0003460 arm bone http://purl.obolibrary.org/obo/UBERON_0008962 forelimb bone A bone that is part of the region of the forelimb that includes the zeugopod and stylopod. Examples: patella, femur, tibia. http://purl.obolibrary.org/obo/GO_0051970 negative regulation of transmission of nerve impulse http://purl.obolibrary.org/obo/GO_0010648 negative regulation of cell communication Any process that stops, prevents, or reduces the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation. http://purl.obolibrary.org/obo/UBERON_0003461 shoulder bone http://purl.obolibrary.org/obo/UBERON_0010741 bone of pectoral complex A bone that is connected via a shoulder joint (i.e. glenohumeral or acromioclavicular joints). The shoulder bones are the clavicle, scapula and humerus - but note that these are only considered to be shoulder bones when a true shoulder is present, as in most tetrapods. http://purl.obolibrary.org/obo/GO_0051971 positive regulation of transmission of nerve impulse http://purl.obolibrary.org/obo/GO_0010647 positive regulation of cell communication Any process that activates, maintains or increases the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation. http://purl.obolibrary.org/obo/UBERON_0003462 facial bone http://purl.obolibrary.org/obo/UBERON_0003457 head bone A bone that is part of a facial skeleton [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0055003 cardiac myofibril assembly http://purl.obolibrary.org/obo/GO_0030239 myofibril assembly The process whose specific outcome is the progression of the cardiac myofibril over time, from its formation to the mature structure. A cardiac myofibril is a myofibril specific to cardiac muscle cells. http://purl.obolibrary.org/obo/UBERON_0003463 trunk bone http://purl.obolibrary.org/obo/UBERON_0005177 trunk region element A bone that is part of a trunk [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0055006 cardiac cell development http://purl.obolibrary.org/obo/GO_0048468 cell development The process whose specific outcome is the progression of a cardiac cell over time, from its formation to the mature state. A cardiac cell is a cell that will form part of the cardiac organ of an individual. http://purl.obolibrary.org/obo/UBERON_0003464 hindlimb bone http://purl.obolibrary.org/obo/UBERON_0015022 hindlimb endochondral element A bone that is part of a hindlimb region. Examples: any pes phalanx, femur. Counter-examples: ischium, pubis (they are part of the pelvic girdle). http://purl.obolibrary.org/obo/GO_0055007 cardiac muscle cell differentiation http://purl.obolibrary.org/obo/GO_0051146 striated muscle cell differentiation The process in which a cardiac muscle precursor cell acquires specialized features of a cardiac muscle cell. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. http://purl.obolibrary.org/obo/UBERON_0003466 forelimb zeugopod bone http://purl.obolibrary.org/obo/UBERON_0003460 arm bone A bone that is part of a lower arm [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0055009 atrial cardiac muscle tissue morphogenesis http://purl.obolibrary.org/obo/GO_0055008 cardiac muscle tissue morphogenesis The process in which the anatomical structure of cardiac atrium muscle is generated and organized. http://purl.obolibrary.org/obo/UBERON_0003468 ureteric segment of renal artery http://purl.obolibrary.org/obo/UBERON_0004573 systemic artery The ureteral branches of renal artery are small branches which supply the ureter. http://purl.obolibrary.org/obo/GO_0055011 atrial cardiac muscle cell differentiation http://purl.obolibrary.org/obo/GO_0055007 cardiac muscle cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a cardiac muscle cell in the atrium. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. The atrium is the part of the heart that receives blood into the organ. http://purl.obolibrary.org/obo/UBERON_0003469 respiratory system artery http://purl.obolibrary.org/obo/UBERON_0003643 respiratory system arterial blood vessel An artery that is part of a respiratory system [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0055014 atrial cardiac muscle cell development http://purl.obolibrary.org/obo/GO_0055013 cardiac muscle cell development The process whose specific outcome is the progression of an atrial cardiac muscle cell over time, from its formation to the mature state. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. The atrium is the part of the heart that receives blood into the organ. http://purl.obolibrary.org/obo/UBERON_0003470 artery of upper lip http://purl.obolibrary.org/obo/UBERON_0009657 artery of lip The superior labial artery (superior labial branch of facial artery) is larger and more tortuous than the inferior labial artery. It follows a similar course along the edge of the upper lip, lying between the mucous membrane and the Orbicularis oris, and anastomoses with the artery of the opposite side. It supplies the upper lip, and gives off in its course two or three vessels which ascend to the nose; a septal branch ramifies on the nasal septum as far as the point of the nose, and an alar branch supplies the ala of the nose. http://purl.obolibrary.org/obo/GO_0055018 regulation of cardiac muscle fiber development http://purl.obolibrary.org/obo/GO_2000725 regulation of cardiac muscle cell differentiation Any process that modulates the frequency, rate or extent of cardiac muscle fiber development. http://purl.obolibrary.org/obo/UBERON_0003471 artery of lower lip http://purl.obolibrary.org/obo/UBERON_0009657 artery of lip The inferior labial artery (inferior labial branch of facial artery) arises near the angle of the mouth; it passes upward and forward beneath the Triangularis and, penetrating the Orbicularis oris, runs in a tortuous course along the edge of the lower lip between this muscle and the mucous membrane. It supplies the labial glands, the mucous membrane, and the muscles of the lower lip; and anastomoses with the artery of the opposite side, and with the mental branch of the inferior alveolar artery. http://purl.obolibrary.org/obo/GO_0055019 negative regulation of cardiac muscle fiber development http://purl.obolibrary.org/obo/GO_0055018 regulation of cardiac muscle fiber development Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle fiber development. http://purl.obolibrary.org/obo/UBERON_0003472 cerebellar artery http://purl.obolibrary.org/obo/UBERON_0003496 head blood vessel An artery that supplies blood to the cerebellum. http://purl.obolibrary.org/obo/GO_0055020 positive regulation of cardiac muscle fiber development http://purl.obolibrary.org/obo/GO_2000727 positive regulation of cardiac muscle cell differentiation Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle fiber development. http://purl.obolibrary.org/obo/UBERON_0003473 thoracic cavity artery http://purl.obolibrary.org/obo/UBERON_0003519 thoracic cavity blood vessel An artery that is part of a thoracic cavity[cjm]. http://purl.obolibrary.org/obo/GO_0055021 regulation of cardiac muscle tissue growth http://purl.obolibrary.org/obo/GO_0060420 regulation of heart growth Any process that modulates the frequency, rate or extent of cardiac muscle growth. http://purl.obolibrary.org/obo/UBERON_0003474 meningeal artery http://purl.obolibrary.org/obo/UBERON_0001637 artery One of the arteries supplying a meninix[Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0055022 negative regulation of cardiac muscle tissue growth http://purl.obolibrary.org/obo/GO_0061117 negative regulation of heart growth Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle growth. http://purl.obolibrary.org/obo/UBERON_0003475 ureteric vein http://purl.obolibrary.org/obo/UBERON_0003520 pelvis blood vessel A vein that is part of a ureter [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0055023 positive regulation of cardiac muscle tissue growth http://purl.obolibrary.org/obo/GO_0060421 positive regulation of heart growth Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle growth. http://purl.obolibrary.org/obo/UBERON_0003476 respiratory system venous blood vessel http://purl.obolibrary.org/obo/UBERON_0001638 vein A vein that is part of a respiratory system [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0055024 regulation of cardiac muscle tissue development http://purl.obolibrary.org/obo/GO_0016202 regulation of striated muscle tissue development Any process that modulates the frequency, rate or extent of cardiac muscle tissue development. http://purl.obolibrary.org/obo/UBERON_0003477 vein of upper lip http://purl.obolibrary.org/obo/UBERON_0013136 vein of lip The inferior labial vein is the vein receiving blood from the upper lip. http://purl.obolibrary.org/obo/GO_0055025 positive regulation of cardiac muscle tissue development http://purl.obolibrary.org/obo/GO_0055024 regulation of cardiac muscle tissue development Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle tissue development. http://purl.obolibrary.org/obo/UBERON_0003478 vein of lower lip http://purl.obolibrary.org/obo/UBERON_0013136 vein of lip The inferior labial vein is the vein receiving blood from the lower lip. http://purl.obolibrary.org/obo/GO_0055026 negative regulation of cardiac muscle tissue development http://purl.obolibrary.org/obo/GO_0055024 regulation of cardiac muscle tissue development Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle tissue development. http://purl.obolibrary.org/obo/UBERON_0003479 thoracic cavity vein http://purl.obolibrary.org/obo/UBERON_0003519 thoracic cavity blood vessel A vein that is part of a thoracic cavity [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0055056 D-glucose transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0015149 hexose transmembrane transporter activity Enables the transfer of the D-enantiomer of the hexose monosaccharide glucose from one side of a membrane to the other. http://purl.obolibrary.org/obo/UBERON_0003480 vein of clitoris http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure A vein that is part of a clitoris [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0055089 fatty acid homeostasis http://purl.obolibrary.org/obo/GO_0055088 lipid homeostasis Any process involved in the maintenance of an internal steady state of fatty acid within an organism or cell. http://purl.obolibrary.org/obo/UBERON_0003481 tail vein http://purl.obolibrary.org/obo/UBERON_0003524 tail blood vessel A vein that is part of a tail [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0055094 response to lipoprotein particle http://purl.obolibrary.org/obo/GO_0009719 response to endogenous stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoprotein particle stimulus. http://purl.obolibrary.org/obo/UBERON_0003483 thymus lymphoid tissue http://purl.obolibrary.org/obo/UBERON_0001744 lymphoid tissue A portion of lymphoid tissue that is part of a thymus [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0055107 Golgi to secretory granule transport http://purl.obolibrary.org/obo/GO_0046907 intracellular transport The directed movement of proteins from the Golgi to a secretory granule. The secretory granule is a membrane-bounded particle, usually protein, formed in the granular endoplasmic reticulum and the Golgi complex. http://purl.obolibrary.org/obo/UBERON_0003484 eye sebaceous gland http://purl.obolibrary.org/obo/UBERON_0003605 eye skin gland A sebaceous gland that is part of a camera-type eye. Example: a tarsal gland. http://purl.obolibrary.org/obo/GO_0055111 ingression involved in gastrulation with mouth forming second http://purl.obolibrary.org/obo/GO_0042074 cell migration involved in gastrulation The migration of individual cells into the embryo involved in deuterostomic gastrulation. http://purl.obolibrary.org/obo/UBERON_0003485 vagina sebaceous gland http://purl.obolibrary.org/obo/UBERON_0005398 female reproductive gland A sebaceous gland that is part of a vagina [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0055118 negative regulation of cardiac muscle contraction http://purl.obolibrary.org/obo/GO_0055117 regulation of cardiac muscle contraction Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle contraction. http://purl.obolibrary.org/obo/UBERON_0003487 skin sebaceous gland http://purl.obolibrary.org/obo/UBERON_0001821 sebaceous gland A holocrine gland of the dermis that secretes sebum into hair follicles. http://purl.obolibrary.org/obo/GO_0055127 vibrational conductance of sound to the inner ear http://purl.obolibrary.org/obo/GO_0032501 multicellular organismal process The transmission of vibrations via ossicles to the inner ear. http://purl.obolibrary.org/obo/UBERON_0003488 abdominal mammary gland http://purl.obolibrary.org/obo/UBERON_0005172 abdomen element A lactiferous gland that is part of the abdominal region [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060005 vestibular reflex http://purl.obolibrary.org/obo/GO_0060004 reflex A reflex process in which a response to an angular or linear acceleration stimulus begins with an afferent nerve impulse from a receptor in the inner ear and ends with the compensatory action of eye muscles. Signaling never reaches a level of consciousness. http://purl.obolibrary.org/obo/UBERON_0003489 respiratory system capillary endothelium http://purl.obolibrary.org/obo/UBERON_0004702 respiratory system blood vessel endothelium An endothelium of capillary that is part of a respiratory system [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060007 linear vestibuloocular reflex http://purl.obolibrary.org/obo/GO_0060005 vestibular reflex A vestibular reflex by which a response to a linear acceleration stimulus begins with an afferent nerve impulse from a receptor in the otolith and ends with the compensatory action of eye muscles. Signaling never reaches a level of consciousness. http://purl.obolibrary.org/obo/UBERON_0003494 respiratory system venule http://purl.obolibrary.org/obo/UBERON_0003504 respiratory system blood vessel A venule that is part of a respiratory system [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060008 Sertoli cell differentiation http://purl.obolibrary.org/obo/GO_0030855 epithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a Sertoli cell. A Sertoli cell is a supporting cell projecting inward from the basement membrane of seminiferous tubules. http://purl.obolibrary.org/obo/UBERON_0003495 respiratory system arteriole http://purl.obolibrary.org/obo/UBERON_0003643 respiratory system arterial blood vessel An arteriole that is part of a respiratory system [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060009 Sertoli cell development http://purl.obolibrary.org/obo/GO_0003006 developmental process involved in reproduction The process whose specific outcome is the progression of a Sertoli cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a Sertoli cell fate. http://purl.obolibrary.org/obo/UBERON_0003496 head blood vessel http://purl.obolibrary.org/obo/UBERON_0001981 blood vessel A blood vessel that is part of a head [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060011 Sertoli cell proliferation http://purl.obolibrary.org/obo/GO_0050673 epithelial cell proliferation The multiplication or reproduction of Sertoli cells, resulting in the expansion of the Sertoli cell population. A Sertoli cell is a supporting cell projecting inward from the basement membrane of seminiferous tubules. http://purl.obolibrary.org/obo/UBERON_0003497 abdomen blood vessel http://purl.obolibrary.org/obo/UBERON_0003835 abdominal segment blood vessel A blood vessel that is part of an abdomen [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060012 synaptic transmission, glycinergic http://purl.obolibrary.org/obo/GO_0007268 chemical synaptic transmission The vesicular release of glycine from a presynapse, across a chemical synapse, the subsequent activation of glycine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse. http://purl.obolibrary.org/obo/UBERON_0003498 heart blood vessel http://purl.obolibrary.org/obo/UBERON_0005985 coronary vessel A blood vessel that is part of a heart [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060014 granulosa cell differentiation http://purl.obolibrary.org/obo/GO_0030855 epithelial cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a granulosa cell, a supporting cell for the developing female gamete in the ovary of mammals. http://purl.obolibrary.org/obo/UBERON_0003499 brain blood vessel http://purl.obolibrary.org/obo/UBERON_0001981 blood vessel A blood vessel that is part of a brain [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060016 granulosa cell development http://purl.obolibrary.org/obo/GO_0002064 epithelial cell development The process whose specific outcome is the progression of a granulosa cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a granulosa cell fate. http://purl.obolibrary.org/obo/UBERON_0003500 corneal blood vessel http://purl.obolibrary.org/obo/UBERON_0003496 head blood vessel A blood vessel that is part of a cornea [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060017 parathyroid gland development http://purl.obolibrary.org/obo/GO_0048732 gland development The process whose specific outcome is the progression of the parathyroid gland over time, from its formation to the mature structure. The parathyroid gland is an organ specialised for secretion of parathyroid hormone. http://purl.obolibrary.org/obo/UBERON_0003501 retina blood vessel http://purl.obolibrary.org/obo/UBERON_0003496 head blood vessel A blood vessel that is part of a retina [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060020 Bergmann glial cell differentiation http://purl.obolibrary.org/obo/GO_0048708 astrocyte differentiation The process in which neuroepithelial cells of the neural tube give rise to Brgmann glial cells, specialized bipotential progenitors cells of the cerebellum. Differentiation includes the processes involved in commitment of a cell to a specific fate. http://purl.obolibrary.org/obo/UBERON_0003502 neck blood vessel http://purl.obolibrary.org/obo/UBERON_0001981 blood vessel A blood vessel that is part of a neck [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060021 roof of mouth development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The biological process whose specific outcome is the progression of the roof of the mouth from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The roof of the mouth is the partition that separates the nasal and oral cavities. http://purl.obolibrary.org/obo/UBERON_0003503 leg blood vessel http://purl.obolibrary.org/obo/UBERON_0003516 hindlimb blood vessel A blood vessel that is part of a leg [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003504 respiratory system blood vessel http://purl.obolibrary.org/obo/UBERON_0001981 blood vessel A blood vessel that is part of a respiratory system [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060034 notochord cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features cells that make up the notochord. Differentiation includes the processes involved in commitment of a cell to a notochord cell fate. http://purl.obolibrary.org/obo/UBERON_0003505 trachea blood vessel http://purl.obolibrary.org/obo/UBERON_0003504 respiratory system blood vessel A blood vessel that is part of a trachea. http://purl.obolibrary.org/obo/GO_0060037 pharyngeal system development http://purl.obolibrary.org/obo/GO_0048731 system development The process whose specific outcome is the progression of the pharyngeal system over time, from its formation to the mature structure. The pharyngeal system is a transient embryonic complex that is specific to vertebrates. It comprises the pharyngeal arches, bulges of tissues of mesoderm and neural crest derivation through which pass nerves and pharyngeal arch arteries. The arches are separated internally by pharyngeal pouches, evaginations of foregut endoderm, and externally by pharyngeal clefts, invaginations of surface ectoderm. The development of the system ends when the structure it contributes to are forming: the thymus, thyroid, parathyroids, maxilla, mandible, aortic arch, cardiac outflow tract, external and middle ear. http://purl.obolibrary.org/obo/UBERON_0003506 chest blood vessel http://purl.obolibrary.org/obo/UBERON_0003834 thoracic segment blood vessel A blood vessel that is part of a chest [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060038 cardiac muscle cell proliferation http://purl.obolibrary.org/obo/GO_0014855 striated muscle cell proliferation The expansion of a cardiac muscle cell population by cell division. http://purl.obolibrary.org/obo/UBERON_0003507 arm blood vessel http://purl.obolibrary.org/obo/UBERON_0003515 forelimb blood vessel A blood vessel that is part of an arm [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060040 retinal bipolar neuron differentiation http://purl.obolibrary.org/obo/GO_1905962 glutamatergic neuron differentiation The process in which a relatively unspecialized cell acquires specialized features of a bipolar cell, the last neuron to be generated in the retina. http://purl.obolibrary.org/obo/UBERON_0003508 pedal digit blood vessel http://purl.obolibrary.org/obo/UBERON_0003521 pes blood vessel A blood vessel that is part of a toe [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060043 regulation of cardiac muscle cell proliferation http://purl.obolibrary.org/obo/GO_0055021 regulation of cardiac muscle tissue growth Any process that modulates the frequency, rate or extent of cardiac muscle cell proliferation. http://purl.obolibrary.org/obo/UBERON_0003509 arterial blood vessel http://purl.obolibrary.org/obo/UBERON_0001981 blood vessel A blood vessel that is part of the arterial system. Includes artery, arteriole and aorta. http://purl.obolibrary.org/obo/GO_0060044 negative regulation of cardiac muscle cell proliferation http://purl.obolibrary.org/obo/GO_0060043 regulation of cardiac muscle cell proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle cell proliferation. http://purl.obolibrary.org/obo/UBERON_0003510 eyelid blood vessel http://purl.obolibrary.org/obo/UBERON_0003496 head blood vessel A blood vessel that is part of a eyelid [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060045 positive regulation of cardiac muscle cell proliferation http://purl.obolibrary.org/obo/GO_0060043 regulation of cardiac muscle cell proliferation Any process that activates or increases the frequency, rate or extent of cardiac muscle cell proliferation. http://purl.obolibrary.org/obo/UBERON_0003511 iris blood vessel http://purl.obolibrary.org/obo/UBERON_0003496 head blood vessel A blood vessel that is part of a iris [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060054 positive regulation of epithelial cell proliferation involved in wound healing http://purl.obolibrary.org/obo/GO_0050679 positive regulation of epithelial cell proliferation Any process that activates or increases the rate or extent of epithelial cell proliferation, contributing to the restoration of integrity to a damaged tissue following an injury. http://purl.obolibrary.org/obo/UBERON_0003512 lung blood vessel http://purl.obolibrary.org/obo/UBERON_0003834 thoracic segment blood vessel A blood vessel that is part of a lung [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060055 angiogenesis involved in wound healing http://purl.obolibrary.org/obo/GO_0001525 angiogenesis Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to a damaged tissue, following an injury. http://purl.obolibrary.org/obo/UBERON_0003513 trunk blood vessel http://purl.obolibrary.org/obo/UBERON_0001981 blood vessel A blood vessel that is part of a trunk [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060067 cervix development http://purl.obolibrary.org/obo/GO_0048608 reproductive structure development The reproductive developmental process whose specific outcome is the progression of the cervix over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/UBERON_0003514 limb blood vessel http://purl.obolibrary.org/obo/UBERON_0007301 appendage blood vessel A blood vessel that is part of a limb [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060068 vagina development http://purl.obolibrary.org/obo/GO_0030540 female genitalia development The reproductive developmental process whose specific outcome is the progression of the vagina over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/UBERON_0003515 forelimb blood vessel http://purl.obolibrary.org/obo/UBERON_0007300 pectoral appendage blood vessel A blood vessel that is part of a forelimb [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060073 micturition http://purl.obolibrary.org/obo/GO_0003014 renal system process The regulation of body fluids process in which parasympathetic nerves stimulate the bladder wall muscle to contract and expel urine from the body. http://purl.obolibrary.org/obo/UBERON_0003516 hindlimb blood vessel http://purl.obolibrary.org/obo/UBERON_0003514 limb blood vessel A blood vessel that is part of a hindlimb [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060076 excitatory synapse http://purl.obolibrary.org/obo/GO_0045202 synapse A synapse in which an action potential in the presynaptic cell increases the probability of an action potential occurring in the postsynaptic cell. http://purl.obolibrary.org/obo/UBERON_0003517 kidney blood vessel http://purl.obolibrary.org/obo/UBERON_0003497 abdomen blood vessel A blood vessel that is part of a kidney [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060078 regulation of postsynaptic membrane potential http://purl.obolibrary.org/obo/GO_0042391 regulation of membrane potential Any process that modulates the potential difference across a post-synaptic membrane. http://purl.obolibrary.org/obo/UBERON_0003519 thoracic cavity blood vessel http://purl.obolibrary.org/obo/UBERON_0001981 blood vessel A blood vessel that is part of a thoracic cavity [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060082 eye blink reflex http://purl.obolibrary.org/obo/GO_0060004 reflex The reflex process in which a mechanical stimulus applied to the eye elicits a response of the eyelid closing. http://purl.obolibrary.org/obo/UBERON_0003520 pelvis blood vessel http://purl.obolibrary.org/obo/UBERON_0003835 abdominal segment blood vessel A blood vessel that is part of a pelvis [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060083 smooth muscle contraction involved in micturition http://purl.obolibrary.org/obo/GO_0014832 urinary bladder smooth muscle contraction The process leading to shortening and/or development of tension in the urinary bladder smooth muscle tissue involved in the expulsion urine from the body. http://purl.obolibrary.org/obo/UBERON_0003521 pes blood vessel http://purl.obolibrary.org/obo/UBERON_0003516 hindlimb blood vessel A blood vessel that is part of a foot [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060084 synaptic transmission involved in micturition http://purl.obolibrary.org/obo/GO_0007274 neuromuscular synaptic transmission The process of communication from a neuron to a smooth muscle in the bladder that contributes to the expulsion of urine from the body. http://purl.obolibrary.org/obo/UBERON_0003522 manual digit blood vessel http://purl.obolibrary.org/obo/UBERON_0003523 manus blood vessel A blood vessel that is part of a finger [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060092 regulation of synaptic transmission, glycinergic http://purl.obolibrary.org/obo/GO_0050804 modulation of chemical synaptic transmission Any process that modulates the frequency, rate or extent of glycinergic synaptic transmission. Glycinergic synaptic transmission is the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glycine. http://purl.obolibrary.org/obo/UBERON_0003523 manus blood vessel http://purl.obolibrary.org/obo/UBERON_0003515 forelimb blood vessel A blood vessel that is part of a manus [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060093 negative regulation of synaptic transmission, glycinergic http://purl.obolibrary.org/obo/GO_0060092 regulation of synaptic transmission, glycinergic Any process that stops or decreases the frequency, rate or extent of glycinergic synaptic transmission. Glycinergic synaptic transmission is the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glycine. http://purl.obolibrary.org/obo/UBERON_0003524 tail blood vessel http://purl.obolibrary.org/obo/UBERON_0001981 blood vessel A blood vessel that is part of a tail [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060094 positive regulation of synaptic transmission, glycinergic http://purl.obolibrary.org/obo/GO_0060092 regulation of synaptic transmission, glycinergic Any process that activates or increases the frequency, rate or extent of glycinergic synaptic transmission. Glycinergic synaptic transmission is the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glycine. http://purl.obolibrary.org/obo/UBERON_0003526 respiratory system capillary http://purl.obolibrary.org/obo/UBERON_0003504 respiratory system blood vessel A capillary that is part of a respiratory system [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060096 serotonin secretion, neurotransmission http://purl.obolibrary.org/obo/GO_0007269 neurotransmitter secretion The regulated release of serotonin by a cell, in which released serotonin acts as a neurotransmitter. http://purl.obolibrary.org/obo/UBERON_0003527 kidney capillary http://purl.obolibrary.org/obo/UBERON_0003517 kidney blood vessel A capillary that is part of a kidney [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003528 brain gray matter http://purl.obolibrary.org/obo/UBERON_0002020 gray matter A gray matter that is part of a brain [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060114 vestibular receptor cell differentiation http://purl.obolibrary.org/obo/GO_0060113 inner ear receptor cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a vestibular hair cell. http://purl.obolibrary.org/obo/UBERON_0003529 respiratory system lymphatic vessel endothelium http://purl.obolibrary.org/obo/UBERON_0004807 respiratory system epithelium An lymphatic vessel endothelium that is part of a respiratory system [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060116 vestibular receptor cell morphogenesis http://purl.obolibrary.org/obo/GO_0048667 cell morphogenesis involved in neuron differentiation Any process that alters the size or shape of a vestibular receptor cell. http://purl.obolibrary.org/obo/UBERON_0003530 pedal digit skin http://purl.obolibrary.org/obo/UBERON_0015249 digit skin A zone of skin that is part of a toe [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060118 vestibular receptor cell development http://purl.obolibrary.org/obo/GO_0060119 inner ear receptor cell development The process whose specific outcome is the progression of a vestibular receptor cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. http://purl.obolibrary.org/obo/UBERON_0003531 forelimb skin http://purl.obolibrary.org/obo/UBERON_0001419 skin of limb A zone of skin that is part of a forelimb [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060119 inner ear receptor cell development http://purl.obolibrary.org/obo/GO_0048666 neuron development The process whose specific outcome is the progression of an inner ear receptor cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. http://purl.obolibrary.org/obo/UBERON_0003532 hindlimb skin http://purl.obolibrary.org/obo/UBERON_0001419 skin of limb A zone of skin that is part of a hindlimb [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060123 regulation of growth hormone secretion http://purl.obolibrary.org/obo/GO_0090276 regulation of peptide hormone secretion Any process that modulates the frequency, rate or extent of the regulated release of growth hormone from a cell. http://purl.obolibrary.org/obo/UBERON_0003533 manual digit skin http://purl.obolibrary.org/obo/UBERON_0015249 digit skin A zone of skin that is part of a finger [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060124 positive regulation of growth hormone secretion http://purl.obolibrary.org/obo/GO_0060123 regulation of growth hormone secretion Any process that increases the frequency, rate or extent of the regulated release of growth hormone from a cell. http://purl.obolibrary.org/obo/UBERON_0003534 tail skin http://purl.obolibrary.org/obo/UBERON_0000014 zone of skin A zone of skin that is part of a tail [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060125 negative regulation of growth hormone secretion http://purl.obolibrary.org/obo/GO_0060123 regulation of growth hormone secretion Any process that decreases or stops the frequency, rate or extent of the regulated release of growth hormone from a cell. http://purl.obolibrary.org/obo/UBERON_0003535 vagus X nerve trunk http://purl.obolibrary.org/obo/UBERON_0002464 nerve trunk A nerve trunk that is part of a vagus nerve. http://purl.obolibrary.org/obo/GO_0060126 somatotropin secreting cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a somatotropin secreting cell. A somatotropin secreting cell is an acidophilic cell of the anterior pituitary that produces growth hormone, somatotropin. http://purl.obolibrary.org/obo/UBERON_0003536 right lung alveolar duct http://purl.obolibrary.org/obo/UBERON_0002173 pulmonary alveolar duct An alveolar duct that is part of a right lung [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060127 prolactin secreting cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a prolactin secreting cell. A prolactin secreting cell is an acidophilic cell of the anterior pituitary that produces prolactin. http://purl.obolibrary.org/obo/UBERON_0003537 left lung alveolar duct http://purl.obolibrary.org/obo/UBERON_0002173 pulmonary alveolar duct An alveolar duct that is part of a left lung [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060128 corticotropin hormone secreting cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a corticotropic hormone secreting cell. An corticotropic hormone secreting cell is a basophil cell of the anterior pituitary that produces corticotropin. http://purl.obolibrary.org/obo/UBERON_0003538 right lung bronchiole http://purl.obolibrary.org/obo/UBERON_0002186 bronchiole A bronchiole that is part of a right lung [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060129 thyroid-stimulating hormone-secreting cell differentiation http://purl.obolibrary.org/obo/GO_0061101 neuroendocrine cell differentiation The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a thyroid-stimulating hormone-secreting cell. A thyroid-stimulating hormone-secreting cell is a basophil cell of the anterior pituitary that produces thyroid-stimulating hormone, thyrotrophin. http://purl.obolibrary.org/obo/UBERON_0003539 left lung bronchiole http://purl.obolibrary.org/obo/UBERON_0002186 bronchiole A bronchiole that is part of a left lung [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060130 thyroid-stimulating hormone-secreting cell development http://purl.obolibrary.org/obo/GO_0021884 forebrain neuron development The process whose specific outcome is the progression of a thyroid-stimulating hormone-secreting cell over time, from its formation to the mature structure. A thyroid-stimulating hormone-secreting cell is a basophil cell of the anterior pituitary that produces thyroid stimulating hormone, thyrotrophin. http://purl.obolibrary.org/obo/UBERON_0003540 right lung terminal bronchiole http://purl.obolibrary.org/obo/UBERON_0003538 right lung bronchiole A terminal bronchiole that is part of a right lung [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060131 corticotropin hormone secreting cell development http://purl.obolibrary.org/obo/GO_0048468 cell development The process whose specific outcome is the progression of a corticotropic hormone secreting cell over time, from its formation to the mature structure. An corticotropic hormone secreting cell is a basophil cell of the anterior pituitary that produces corticotropin. http://purl.obolibrary.org/obo/UBERON_0003541 left lung terminal bronchiole http://purl.obolibrary.org/obo/UBERON_0003539 left lung bronchiole A terminal bronchiole that is part of a left lung [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060132 prolactin secreting cell development http://purl.obolibrary.org/obo/GO_0048468 cell development The process whose specific outcome is the progression of a prolactin secreting cell over time, from its formation to the mature structure. A prolactin secreting cell is an acidophilic cell of the anterior pituitary that produces prolactin. http://purl.obolibrary.org/obo/UBERON_0003542 right lung respiratory bronchiole http://purl.obolibrary.org/obo/UBERON_0003538 right lung bronchiole A respiratory bronchiole that is part of a right lung [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060133 somatotropin secreting cell development http://purl.obolibrary.org/obo/GO_0048468 cell development The process whose specific outcome is the progression of a somatotropin secreting cell over time, from its formation to the mature structure. A somatotropin secreting cell is an acidophilic cell of the anterior pituitary that produces growth hormone, somatotropin. http://purl.obolibrary.org/obo/UBERON_0003543 left lung respiratory bronchiole http://purl.obolibrary.org/obo/UBERON_0003539 left lung bronchiole A respiratory bronchiole that is part of a left lung [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060136 embryonic process involved in female pregnancy http://purl.obolibrary.org/obo/GO_0048609 multicellular organismal reproductive process A reproductive process occurring in the embryo or fetus that allows the embryo or fetus to develop within the mother. http://purl.obolibrary.org/obo/UBERON_0003544 brain white matter http://purl.obolibrary.org/obo/UBERON_0002316 white matter The regions of the brain that are largely or entirely composed of myelinated nerve cell axons and contain few or no neural cell bodies or dendrites. http://purl.obolibrary.org/obo/GO_0060157 urinary bladder development http://purl.obolibrary.org/obo/GO_0048513 animal organ development The process whose specific outcome is the progression of the urinary bladder over time, from its formation to the mature structure. The urinary bladder is an elastic, muscular sac situated in the anterior part of the pelvic cavity in which urine collects before excretion. http://purl.obolibrary.org/obo/UBERON_0003546 distal convoluted tubule macula densa http://purl.obolibrary.org/obo/UBERON_0002335 macula densa A macula densa that is part of a distal convoluted tubule [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060166 olfactory pit development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The biological process whose specific outcome is the progression of the olfactory pit from an initial condition to its mature state. This process begins with the formation of the olfactory pit, which is an indentation of the olfactory placode, and ends when the pits hollows out to form the nasopharynx. http://purl.obolibrary.org/obo/UBERON_0003547 brain meninx http://purl.obolibrary.org/obo/UBERON_0002360 meninx A meninx that is part of a brain [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060214 endocardium formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis Formation of the endocardium of the heart. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers. http://purl.obolibrary.org/obo/UBERON_0003548 forebrain meninges http://purl.obolibrary.org/obo/UBERON_0003547 brain meninx A meninx that is part of a forebrain [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060215 primitive hemopoiesis http://purl.obolibrary.org/obo/GO_0035162 embryonic hemopoiesis A first transient wave of blood cell production that, in vertebrates, gives rise to erythrocytes (red blood cells) and myeloid cells. http://purl.obolibrary.org/obo/UBERON_0003549 brain pia mater http://purl.obolibrary.org/obo/UBERON_0003547 brain meninx The fibrous membrane forming the innermost of the three coverings that surrounds the brain within the cranial cavity that is firmly attached to the glial capsule. http://purl.obolibrary.org/obo/GO_0060217 hemangioblast cell differentiation http://purl.obolibrary.org/obo/GO_0048333 mesodermal cell differentiation The process in which a relatively unspecialized cell acquires the characteristics of a mature hemangioblast. Hemangioblasts are the proposed common precursor of blood and endothelial lineages. http://purl.obolibrary.org/obo/UBERON_0003550 forebrain pia mater http://purl.obolibrary.org/obo/UBERON_0003549 brain pia mater A pia mater that is part of a forebrain [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060218 hematopoietic stem cell differentiation http://purl.obolibrary.org/obo/GO_0048863 stem cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a hematopoietic stem cell. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells. http://purl.obolibrary.org/obo/UBERON_0003551 midbrain pia mater http://purl.obolibrary.org/obo/UBERON_0003549 brain pia mater A pia mater that is part of a midbrain [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060221 retinal rod cell differentiation http://purl.obolibrary.org/obo/GO_0060219 camera-type eye photoreceptor cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a retinal rod cell. http://purl.obolibrary.org/obo/UBERON_0003552 telencephalon pia mater http://purl.obolibrary.org/obo/UBERON_0003550 forebrain pia mater A pia mater that is part of a telencephalon [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060263 regulation of respiratory burst http://purl.obolibrary.org/obo/GO_0019222 regulation of metabolic process Any process that modulates the rate frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals. http://purl.obolibrary.org/obo/UBERON_0003553 diencephalon pia mater http://purl.obolibrary.org/obo/UBERON_0003550 forebrain pia mater A pia mater that is part of a diencephalon [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060264 regulation of respiratory burst involved in inflammatory response http://purl.obolibrary.org/obo/GO_0060263 regulation of respiratory burst Any process that modulates the rate, frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases made as a defense response ; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals. http://purl.obolibrary.org/obo/UBERON_0003554 hindbrain pia mater http://purl.obolibrary.org/obo/UBERON_0003549 brain pia mater A pia mater that is part of a hindbrain [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060265 positive regulation of respiratory burst involved in inflammatory response http://purl.obolibrary.org/obo/GO_0060267 positive regulation of respiratory burst Any process that increases the rate, frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases made as a defense response ; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals. http://purl.obolibrary.org/obo/UBERON_0003555 spinal cord pia mater http://purl.obolibrary.org/obo/UBERON_0002361 pia mater A pia mater that is part of a spinal cord [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060266 negative regulation of respiratory burst involved in inflammatory response http://purl.obolibrary.org/obo/GO_0060268 negative regulation of respiratory burst Any process that decreases the rate, frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases made as a defense response ; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals. http://purl.obolibrary.org/obo/UBERON_0003556 forebrain arachnoid mater http://purl.obolibrary.org/obo/UBERON_0003548 forebrain meninges An arachnoid mater that is part of a forebrain [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060267 positive regulation of respiratory burst http://purl.obolibrary.org/obo/GO_0060263 regulation of respiratory burst Any process that increases the rate frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals. http://purl.obolibrary.org/obo/UBERON_0003557 midbrain arachnoid mater http://purl.obolibrary.org/obo/UBERON_0003288 meninx of midbrain An arachnoid mater that is part of a midbrain [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060268 negative regulation of respiratory burst http://purl.obolibrary.org/obo/GO_0060263 regulation of respiratory burst Any process that decreases the rate frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals. http://purl.obolibrary.org/obo/UBERON_0003558 diencephalon arachnoid mater http://purl.obolibrary.org/obo/UBERON_0003556 forebrain arachnoid mater An arachnoid mater that is part of a diencephalon [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003559 hindbrain arachnoid mater http://purl.obolibrary.org/obo/UBERON_0003291 meninx of hindbrain An arachnoid mater that is part of a hindbrain [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060269 centripetally migrating follicle cell migration http://purl.obolibrary.org/obo/GO_0007297 follicle cell of egg chamber migration The cell migration process in which a follicle cell migrates as part of an epithelial sheet between the nurse cells and the oocyte. At the end of migration, they cover the anterior of the oocyte. http://purl.obolibrary.org/obo/UBERON_0003560 spinal cord arachnoid mater http://purl.obolibrary.org/obo/UBERON_0002362 arachnoid mater An arachnoid mater that is part of a spinal cord [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060285 cilium-dependent cell motility http://purl.obolibrary.org/obo/GO_0001539 cilium or flagellum-dependent cell motility Cell motility due to the motion of one or more eukaryotic cilia. A eukaryotic cilium is a specialized organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole. http://purl.obolibrary.org/obo/UBERON_0003561 forebrain dura mater http://purl.obolibrary.org/obo/UBERON_0003548 forebrain meninges A dura mater that is part of a forebrain. http://purl.obolibrary.org/obo/GO_0060294 cilium movement involved in cell motility http://purl.obolibrary.org/obo/GO_0003341 cilium movement Movement of cilia mediated by motor proteins that contributes to the movement of a cell. http://purl.obolibrary.org/obo/UBERON_0003562 midbrain dura mater http://purl.obolibrary.org/obo/UBERON_0003288 meninx of midbrain A dura mater that is part of a midbrain [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060295 regulation of cilium movement involved in cell motility http://purl.obolibrary.org/obo/GO_1902019 regulation of cilium-dependent cell motility Any process that modulates the rate frequency or extent of cilium movement involved in ciliary motility. http://purl.obolibrary.org/obo/UBERON_0003563 telencephalon dura mater http://purl.obolibrary.org/obo/UBERON_0003561 forebrain dura mater A dura mater that is part of a telencephalon [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060297 regulation of sarcomere organization http://purl.obolibrary.org/obo/GO_0110020 regulation of actomyosin structure organization Any process that modulates the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs. http://purl.obolibrary.org/obo/UBERON_0003564 diencephalon dura mater http://purl.obolibrary.org/obo/UBERON_0003561 forebrain dura mater A dura mater that is part of a diencephalon [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003565 hindbrain dura mater http://purl.obolibrary.org/obo/UBERON_0003291 meninx of hindbrain A dura mater that is part of a hindbrain [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003566 head connective tissue http://purl.obolibrary.org/obo/UBERON_0002384 connective tissue A portion of connective tissue that is part of a head [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060298 positive regulation of sarcomere organization http://purl.obolibrary.org/obo/GO_0060297 regulation of sarcomere organization Any process that increases the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs. http://purl.obolibrary.org/obo/UBERON_0003567 abdomen connective tissue http://purl.obolibrary.org/obo/UBERON_0003838 abdominal segment connective tissue A portion of connective tissue that is part of an abdomen [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060299 negative regulation of sarcomere organization http://purl.obolibrary.org/obo/GO_0060297 regulation of sarcomere organization Any process that decreases the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs. http://purl.obolibrary.org/obo/UBERON_0003568 neck connective tissue http://purl.obolibrary.org/obo/UBERON_0002384 connective tissue A portion of connective tissue that is part of a neck [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060306 regulation of membrane repolarization http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process Any process that modulates the establishment or extent of a membrane potential in the polarizing direction towards the resting potential, usually from positive to negative. http://purl.obolibrary.org/obo/UBERON_0003569 leg connective tissue http://purl.obolibrary.org/obo/UBERON_0003589 hindlimb connective tissue A portion of connective tissue that is part of a leg [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060307 regulation of ventricular cardiac muscle cell membrane repolarization http://purl.obolibrary.org/obo/GO_0099623 regulation of cardiac muscle cell membrane repolarization Any process that modulates the establishment or extent of a membrane potential in the polarizing direction towards the resting potential in a ventricular cardiomyocyte. http://purl.obolibrary.org/obo/UBERON_0003570 respiratory system connective tissue http://purl.obolibrary.org/obo/UBERON_0002384 connective tissue A portion of connective tissue that is part of a respiratory system [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060312 regulation of blood vessel remodeling http://purl.obolibrary.org/obo/GO_0034103 regulation of tissue remodeling Any process that modulates the rate, frequency or extent of blood vessel remodeling, the reorganization or renovation of existing blood vessels. http://purl.obolibrary.org/obo/UBERON_0003571 trachea connective tissue http://purl.obolibrary.org/obo/UBERON_0003580 lower respiratory tract connective tissue A portion of connective tissue that is part of a trachea. http://purl.obolibrary.org/obo/GO_0060313 negative regulation of blood vessel remodeling http://purl.obolibrary.org/obo/GO_0060312 regulation of blood vessel remodeling Any process that decreases the rate, frequency or extent of blood vessel remodeling, the reorganization or renovation of existing blood vessels. http://purl.obolibrary.org/obo/UBERON_0003572 chest connective tissue http://purl.obolibrary.org/obo/UBERON_0003837 thoracic segment connective tissue A portion of connective tissue that is part of a chest [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060323 head morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structures of the head are generated and organized. The head is the anterior-most division of the body. http://purl.obolibrary.org/obo/UBERON_0003573 arm connective tissue http://purl.obolibrary.org/obo/UBERON_0003588 forelimb connective tissue A portion of connective tissue that is part of an arm [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060324 face development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The biological process whose specific outcome is the progression of a face from an initial condition to its mature state. The face is the ventral division of the head. http://purl.obolibrary.org/obo/UBERON_0003574 elbow connective tissue http://purl.obolibrary.org/obo/UBERON_0003573 arm connective tissue A portion of connective tissue that is part of a elbow [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060325 face morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structures of the face are generated and organized. The face is the ventral division of the head. http://purl.obolibrary.org/obo/UBERON_0003575 wrist connective tissue http://purl.obolibrary.org/obo/UBERON_0003598 manus connective tissue A portion of connective tissue that is part of a wrist [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060343 trabecula formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process of creating a trabecula in an organ. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue. http://purl.obolibrary.org/obo/UBERON_0003576 hip connective tissue http://purl.obolibrary.org/obo/UBERON_0002384 connective tissue A portion of connective tissue that is part of a hip [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060344 liver trabecula formation http://purl.obolibrary.org/obo/GO_0060343 trabecula formation The process of creating a trabecula in the liver. A trabecula is a tissue element in the form of a small beam, strut or rod. http://purl.obolibrary.org/obo/UBERON_0003577 knee connective tissue http://purl.obolibrary.org/obo/UBERON_0003569 leg connective tissue A portion of connective tissue that is part of a knee [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060345 spleen trabecula formation http://purl.obolibrary.org/obo/GO_0060343 trabecula formation The process of creating a trabecula in the spleen. A trabecula is a tissue element in the form of a small beam, strut or rod. http://purl.obolibrary.org/obo/UBERON_0003578 pedal digit connective tissue http://purl.obolibrary.org/obo/UBERON_0015791 digit connective tissue A portion of connective tissue that is part of a toe [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060347 heart trabecula formation http://purl.obolibrary.org/obo/GO_0060343 trabecula formation The process of creating a trabecula in the heart. A trabecula is a tissue element in the form of a small beam, strut or rod. http://purl.obolibrary.org/obo/UBERON_0003579 shoulder connective tissue http://purl.obolibrary.org/obo/UBERON_0002384 connective tissue A portion of connective tissue that is part of a shoulder [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060349 bone morphogenesis http://purl.obolibrary.org/obo/GO_0009887 animal organ morphogenesis The process in which bones are generated and organized. http://purl.obolibrary.org/obo/UBERON_0003580 lower respiratory tract connective tissue http://purl.obolibrary.org/obo/UBERON_0003570 respiratory system connective tissue A portion of connective tissue that is part of a lower respiratory tract [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003581 eyelid connective tissue http://purl.obolibrary.org/obo/UBERON_0003566 head connective tissue A portion of connective tissue that is part of a eyelid [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060363 cranial suture morphogenesis http://purl.obolibrary.org/obo/GO_0097094 craniofacial suture morphogenesis The process in which any suture between cranial bones is generated and organized. http://purl.obolibrary.org/obo/UBERON_0003582 nasopharynx connective tissue http://purl.obolibrary.org/obo/UBERON_0003570 respiratory system connective tissue A portion of connective tissue that is part of a nasopharynx [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060364 frontal suture morphogenesis http://purl.obolibrary.org/obo/GO_0060363 cranial suture morphogenesis The process in which the frontal suture is generated and organized. http://purl.obolibrary.org/obo/UBERON_0003583 larynx connective tissue http://purl.obolibrary.org/obo/UBERON_0003570 respiratory system connective tissue A portion of connective tissue that is part of a larynx [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060372 regulation of atrial cardiac muscle cell membrane repolarization http://purl.obolibrary.org/obo/GO_0099623 regulation of cardiac muscle cell membrane repolarization Any process that modulates the establishment or extent of a membrane potential in the polarizing direction towards the resting potential in an atrial cardiomyocyte. http://purl.obolibrary.org/obo/UBERON_0003584 mammary gland connective tissue http://purl.obolibrary.org/obo/UBERON_0002384 connective tissue The fibrous supportive tissue of the mammary gland. http://purl.obolibrary.org/obo/GO_0060374 mast cell differentiation http://purl.obolibrary.org/obo/GO_0002573 myeloid leukocyte differentiation The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a mast cell. A mast cell is a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation. http://purl.obolibrary.org/obo/UBERON_0003585 dermis connective tissue http://purl.obolibrary.org/obo/UBERON_0010313 neural crest-derived structure A portion of connective tissue that is part of a dermis [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060375 regulation of mast cell differentiation http://purl.obolibrary.org/obo/GO_0002761 regulation of myeloid leukocyte differentiation Any process that modulates the rate, frequency or extent of mast cell differentiation, the process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a mast cell. A mast cell is a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation. http://purl.obolibrary.org/obo/UBERON_0003586 trunk connective tissue http://purl.obolibrary.org/obo/UBERON_0002384 connective tissue A portion of connective tissue that is part of a trunk [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060376 positive regulation of mast cell differentiation http://purl.obolibrary.org/obo/GO_0060375 regulation of mast cell differentiation Any process that increases the rate, frequency or extent of mast cell differentiation, the process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a mast cell. A mast cell is a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation. http://purl.obolibrary.org/obo/UBERON_0003587 limb connective tissue http://purl.obolibrary.org/obo/UBERON_0002384 connective tissue A portion of connective tissue that is part of a limb [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060377 negative regulation of mast cell differentiation http://purl.obolibrary.org/obo/GO_0060375 regulation of mast cell differentiation Any process that decreases the rate, frequency or extent of mast cell differentiation, the process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a mast cell. A mast cell is a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation. http://purl.obolibrary.org/obo/UBERON_0003588 forelimb connective tissue http://purl.obolibrary.org/obo/UBERON_0003587 limb connective tissue A portion of connective tissue that is part of a forelimb [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060408 regulation of acetylcholine metabolic process http://purl.obolibrary.org/obo/GO_0080090 regulation of primary metabolic process Any process that modulates the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues. http://purl.obolibrary.org/obo/UBERON_0003589 hindlimb connective tissue http://purl.obolibrary.org/obo/UBERON_0003587 limb connective tissue A portion of connective tissue that is part of a hindlimb [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060409 positive regulation of acetylcholine metabolic process http://purl.obolibrary.org/obo/GO_0060408 regulation of acetylcholine metabolic process Any process that increases the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues. http://purl.obolibrary.org/obo/UBERON_0003591 lobar bronchus connective tissue http://purl.obolibrary.org/obo/UBERON_0003592 bronchus connective tissue A portion of connective tissue that is part of a lobar bronchus [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060414 aorta smooth muscle tissue morphogenesis http://purl.obolibrary.org/obo/GO_0060415 muscle tissue morphogenesis The process in which the structure of the smooth muscle tissue surrounding the aorta is generated and organized. An aorta is an artery that carries blood from the heart to other parts of the body. http://purl.obolibrary.org/obo/UBERON_0003592 bronchus connective tissue http://purl.obolibrary.org/obo/UBERON_0003580 lower respiratory tract connective tissue A portion of connective tissue that is part of a bronchus [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060420 regulation of heart growth http://purl.obolibrary.org/obo/GO_2000026 regulation of multicellular organismal development Any process that modulates the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart. http://purl.obolibrary.org/obo/UBERON_0003593 thoracic cavity connective tissue http://purl.obolibrary.org/obo/UBERON_0002384 connective tissue A portion of connective tissue that is part of a thoracic cavity [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060421 positive regulation of heart growth http://purl.obolibrary.org/obo/GO_0060420 regulation of heart growth Any process that increases the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart. http://purl.obolibrary.org/obo/UBERON_0003594 pelvis connective tissue http://purl.obolibrary.org/obo/UBERON_0003838 abdominal segment connective tissue A portion of connective tissue that is part of a pelvis [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060425 lung morphogenesis http://purl.obolibrary.org/obo/GO_0009887 animal organ morphogenesis The process in which the anatomical structures of the lung are generated and organized. http://purl.obolibrary.org/obo/UBERON_0003595 pes connective tissue http://purl.obolibrary.org/obo/UBERON_0003589 hindlimb connective tissue A portion of connective tissue that is part of a foot [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060426 lung vasculature development http://purl.obolibrary.org/obo/GO_0001944 vasculature development The biological process whose specific outcome is the progression of a lung vasculature from an initial condition to its mature state. This process begins with the formation of the lung vasculature and ends with the mature structure. The lung vasculature is composed of the tubule structures that carry blood or lymph in the lungs. http://purl.obolibrary.org/obo/UBERON_0003596 ankle connective tissue http://purl.obolibrary.org/obo/UBERON_0003595 pes connective tissue A portion of connective tissue that is part of an ankle [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060427 lung connective tissue development http://purl.obolibrary.org/obo/GO_0061448 connective tissue development The biological process whose specific outcome is the progression of lung connective tissue from an initial condition to its mature state. This process begins with the formation of lung connective tissue and ends with the mature structure. The lung connective tissue is a material made up of fibers forming a framework and support structure for the lungs. http://purl.obolibrary.org/obo/UBERON_0003597 manual digit connective tissue http://purl.obolibrary.org/obo/UBERON_0015791 digit connective tissue A portion of connective tissue that is part of a finger [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060428 lung epithelium development http://purl.obolibrary.org/obo/GO_0060429 epithelium development The biological process whose specific outcome is the progression of the lung epithelium from an initial condition to its mature state. This process begins with the formation of lung epithelium and ends with the mature structure. The lung epithelium is the specialized epithelium that lines the inside of the lung. http://purl.obolibrary.org/obo/UBERON_0003598 manus connective tissue http://purl.obolibrary.org/obo/UBERON_0003588 forelimb connective tissue A portion of connective tissue that is part of a hand [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060431 primary lung bud formation http://purl.obolibrary.org/obo/GO_0060572 morphogenesis of an epithelial bud The morphogenetic process in which the foregut region specified to become the lung forms the initial left and right buds. http://purl.obolibrary.org/obo/UBERON_0003599 tail connective tissue http://purl.obolibrary.org/obo/UBERON_0002384 connective tissue A portion of connective tissue that is part of a tail [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060433 bronchus development http://purl.obolibrary.org/obo/GO_0030323 respiratory tube development The biological process whose specific outcome is the progression of a bronchus from an initial condition to its mature state. This process begins with the formation of the bronchus and ends with the mature structure. The bronchus is the portion of the airway that connects to the lungs. http://purl.obolibrary.org/obo/UBERON_0003601 neck cartilage http://purl.obolibrary.org/obo/UBERON_0007844 cartilage element A cartilage that is part of a neck [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060434 bronchus morphogenesis http://purl.obolibrary.org/obo/GO_0009887 animal organ morphogenesis The process in which the bronchus is generated and organized. The bronchus is the portion of the airway that connects to the lungs. http://purl.obolibrary.org/obo/UBERON_0003603 lower respiratory tract cartilage http://purl.obolibrary.org/obo/UBERON_0003406 cartilage of respiratory system A cartilage that is part of a lower respiratory tract [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060435 bronchiole development http://purl.obolibrary.org/obo/GO_0030323 respiratory tube development The biological process whose specific outcome is the progression of a bronchiole from an initial condition to its mature state. This process begins with the formation of the bronchiole and ends with the mature structure. A bronchiole is the first airway branch that no longer contains cartilage; it is a branch of the bronchi. http://purl.obolibrary.org/obo/UBERON_0003604 trachea cartilage http://purl.obolibrary.org/obo/UBERON_0003603 lower respiratory tract cartilage The ring-shaped cartilaginous structures that support the trachea. http://purl.obolibrary.org/obo/GO_0060436 bronchiole morphogenesis http://purl.obolibrary.org/obo/GO_0035239 tube morphogenesis The process in which a bronchiole is generated and organized. A bronchiole is the first airway branch that no longer contains cartilage; it is a branch of the bronchi. http://purl.obolibrary.org/obo/UBERON_0003605 eye skin gland http://purl.obolibrary.org/obo/UBERON_0015152 gland of ocular region A skin gland that is part of a camera-type eye [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060437 lung growth http://purl.obolibrary.org/obo/GO_0035265 organ growth The increase in size or mass of a lung. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the esophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into tubes ending in small air cells, in the walls of which the blood circulates in a fine network of capillaries. In mammals the lungs are more or less divided into lobes, and each lung occupies a separate cavity in the thorax. http://purl.obolibrary.org/obo/UBERON_0003606 limb long bone http://purl.obolibrary.org/obo/UBERON_0002428 limb bone A long bone that is part of a limb [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060438 trachea development http://purl.obolibrary.org/obo/GO_0048513 animal organ development The process whose specific outcome is the progression of a trachea over time, from its formation to the mature structure. The trachea is the portion of the airway that attaches to the bronchi as it branches. http://purl.obolibrary.org/obo/UBERON_0003607 forelimb long bone http://purl.obolibrary.org/obo/UBERON_0008962 forelimb bone A long bone that is part of a forelimb [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060439 trachea morphogenesis http://purl.obolibrary.org/obo/GO_0009887 animal organ morphogenesis The process in which a trachea is generated and organized. The trachea is the portion of the airway that attaches to the bronchi as it branches. http://purl.obolibrary.org/obo/UBERON_0003608 hindlimb long bone http://purl.obolibrary.org/obo/UBERON_0003606 limb long bone A long bone that is part of a hindlimb [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060440 trachea formation http://purl.obolibrary.org/obo/GO_0048645 animal organ formation The process pertaining to the initial formation of a trachea from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the trachea is recognizable. The trachea is the portion of the airway that attaches to the bronchi as it branches. http://purl.obolibrary.org/obo/UBERON_0003609 aorta elastic tissue http://purl.obolibrary.org/obo/UBERON_0003614 blood vessel elastic tissue The dense connective tissue which contains predominantly elastic fibers and is found in the tunica media of the aorta wall. http://purl.obolibrary.org/obo/GO_0060441 epithelial tube branching involved in lung morphogenesis http://purl.obolibrary.org/obo/GO_0048754 branching morphogenesis of an epithelial tube The process in which a highly ordered sequence of patterning events generates the branched epithelial tubes of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units. http://purl.obolibrary.org/obo/UBERON_0003610 heart elastic tissue http://purl.obolibrary.org/obo/UBERON_0003837 thoracic segment connective tissue The type of heart connective tissue found in the endocardial layer that consists mainly of elastic fibers. http://purl.obolibrary.org/obo/GO_0060442 branching involved in prostate gland morphogenesis http://purl.obolibrary.org/obo/GO_0060740 prostate gland epithelium morphogenesis The process in which the branching structure of the prostate gland is generated and organized. A branch is a division or offshoot from a main stem. http://purl.obolibrary.org/obo/UBERON_0003611 respiratory system elastic tissue http://purl.obolibrary.org/obo/UBERON_0003570 respiratory system connective tissue An elastic tissue that is part of a respiratory system [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060443 mammary gland morphogenesis http://purl.obolibrary.org/obo/GO_0022612 gland morphogenesis The process in which anatomical structures of the mammary gland are generated and organized. Morphogenesis refers to the creation of shape. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk. http://purl.obolibrary.org/obo/UBERON_0003613 cardiovascular system elastic tissue http://purl.obolibrary.org/obo/UBERON_0002521 elastic tissue An elastic tissue that is part of a circulatory system [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060444 branching involved in mammary gland duct morphogenesis http://purl.obolibrary.org/obo/GO_0048754 branching morphogenesis of an epithelial tube The process in which the branching structure of the mammary gland duct is generated and organized. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk. http://purl.obolibrary.org/obo/UBERON_0003614 blood vessel elastic tissue http://purl.obolibrary.org/obo/UBERON_0003613 cardiovascular system elastic tissue Elastic tissue layer that lines a blood vessel layer. http://purl.obolibrary.org/obo/GO_0060445 branching involved in salivary gland morphogenesis http://purl.obolibrary.org/obo/GO_0061138 morphogenesis of a branching epithelium The process in which the branching structure of the salivary gland is generated and organized. http://purl.obolibrary.org/obo/UBERON_0003615 lung elastic tissue http://purl.obolibrary.org/obo/UBERON_0003611 respiratory system elastic tissue Elastic tissue that is part of a lung [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060450 positive regulation of hindgut contraction http://purl.obolibrary.org/obo/GO_0043134 regulation of hindgut contraction Any process that increases the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine. http://purl.obolibrary.org/obo/UBERON_0003616 bronchus elastic tissue http://purl.obolibrary.org/obo/UBERON_0003611 respiratory system elastic tissue An elastic tissue that is part of a bronchus [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060451 negative regulation of hindgut contraction http://purl.obolibrary.org/obo/GO_0060457 negative regulation of digestive system process Any process that decreases the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine. http://purl.obolibrary.org/obo/UBERON_0003617 trachea elastic tissue http://purl.obolibrary.org/obo/UBERON_0003611 respiratory system elastic tissue An elastic tissue that is part of a trachea [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003618 aorta tunica media http://purl.obolibrary.org/obo/UBERON_0002522 tunica media The middle layer of the aorta wall, containing the smooth muscle layer and elastic fibers. http://purl.obolibrary.org/obo/GO_0060452 positive regulation of cardiac muscle contraction http://purl.obolibrary.org/obo/GO_0055117 regulation of cardiac muscle contraction Any process that increases the frequency, rate or extent of cardiac muscle contraction. http://purl.obolibrary.org/obo/UBERON_0003619 aorta tunica intima http://purl.obolibrary.org/obo/UBERON_0004797 blood vessel layer The innermost layer of the aorta, containing the endothelium and an inner elastic membrane. http://purl.obolibrary.org/obo/UBERON_0003643 respiratory system arterial blood vessel http://purl.obolibrary.org/obo/UBERON_0003509 arterial blood vessel An arterial blood vessel that is part of a respiratory system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003644 kidney arterial blood vessel http://purl.obolibrary.org/obo/UBERON_0003517 kidney blood vessel An arterial blood vessel that is part of a kidney [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003656 mesopodium bone http://purl.obolibrary.org/obo/UBERON_0013630 short bone A bone that is part of a mesopodial skeleton. http://purl.obolibrary.org/obo/UBERON_0003657 limb joint http://purl.obolibrary.org/obo/UBERON_0000982 skeletal joint Any joint that is part of a (free) limb. http://purl.obolibrary.org/obo/UBERON_0003658 hip muscle http://purl.obolibrary.org/obo/UBERON_0010890 pelvic complex muscle Any muscle organ that is part of a hip [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003659 pedal digit muscle http://purl.obolibrary.org/obo/UBERON_0001498 muscle of pes Any muscle organ that is part of a toe [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003660 eyelid muscle http://purl.obolibrary.org/obo/UBERON_0001630 muscle organ A muscle that attaches to an eyelid. http://purl.obolibrary.org/obo/UBERON_0003661 limb muscle http://purl.obolibrary.org/obo/UBERON_0014892 skeletal muscle organ, vertebrate Any muscle organ that is part of a limb [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003662 forelimb muscle http://purl.obolibrary.org/obo/UBERON_0014794 pectoral appendage muscle Any muscle organ that is part of a forelimb. http://purl.obolibrary.org/obo/UBERON_0003663 hindlimb muscle http://purl.obolibrary.org/obo/UBERON_0014795 pelvic appendage muscle Any muscle organ that is part of a hindlimb [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003664 manual digit muscle http://purl.obolibrary.org/obo/UBERON_0001500 muscle of manus Any muscle organ that is part of a finger [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003665 post-anal tail muscle http://purl.obolibrary.org/obo/UBERON_0004518 muscle of vertebral column A muscle organ that attaches to a tail vertebra [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003672 dentition http://purl.obolibrary.org/obo/UBERON_0034925 anatomical collection A collection of teeth arranged in some pattern in the mouth or other part of the body. The arrangement may be a simple row, a collection of rows, or a more elaborate structure, such as a toooth whorl. http://purl.obolibrary.org/obo/UBERON_0003677 tooth root http://purl.obolibrary.org/obo/UBERON_0000063 organ subunit The part of a tooth that is implanted in the gum; the root is normally located below the neck of the tooth, covered by cementum rather than enamel, and attached by the periodontal ligament to the alveolar bone. http://purl.obolibrary.org/obo/UBERON_0003684 abdominal cavity http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space The part of the ventral body cavity that is within the abdomen proper (excluding the pelvic cavity). http://purl.obolibrary.org/obo/UBERON_0003685 cranial suture http://purl.obolibrary.org/obo/UBERON_0009198 craniofacial suture Fibrous joint in which the articulating bones or cartilages of the skull are connected by sutural ligaments (scant amount of collagenous dense connective tissue). Examples: sagittal suture, frontal suture. http://purl.obolibrary.org/obo/UBERON_0003688 omentum http://purl.obolibrary.org/obo/UBERON_0034944 zone of organ A fold of peritoneum originating at the stomach and supporting the viscera. http://purl.obolibrary.org/obo/GO_0060453 regulation of gastric acid secretion http://purl.obolibrary.org/obo/GO_0044058 regulation of digestive system process Any process that modulates the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion. http://purl.obolibrary.org/obo/UBERON_0003692 acromioclavicular joint http://purl.obolibrary.org/obo/UBERON_0016884 shoulder joint Any joint connecting the acromonion of the scapula and clavicle. http://purl.obolibrary.org/obo/GO_0060454 positive regulation of gastric acid secretion http://purl.obolibrary.org/obo/GO_0060453 regulation of gastric acid secretion Any process that increases the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion. http://purl.obolibrary.org/obo/UBERON_0003694 atlanto-axial joint http://purl.obolibrary.org/obo/UBERON_0000982 skeletal joint The Atlanto-axial joint is of a complicated nature, comprising no fewer than four distinct joints. There is a pivot articulation between the odontoid process of the axis and the ring formed by the anterior arch and the transverse ligament of the atlas. http://purl.obolibrary.org/obo/GO_0060455 negative regulation of gastric acid secretion http://purl.obolibrary.org/obo/GO_0060457 negative regulation of digestive system process Any process that decreases the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion. http://purl.obolibrary.org/obo/UBERON_0003695 metacarpophalangeal joint http://purl.obolibrary.org/obo/UBERON_0001489 manus joint The metacarpophalangeal joints (MCP) are of the condyloid kind, formed by the reception of the rounded heads of the metacarpal bones into shallow cavities on the proximal ends of the first phalanges, with the exception of that of the thumb, which presents more of the characters of a ginglymoid joint. Arthritis of the MCP is a distinguishing feature of Rheumatoid Arthritis, as opposed to the distal interphalangeal joint in osteoarthritis. [WP,unvetted]. http://purl.obolibrary.org/obo/GO_0060457 negative regulation of digestive system process http://purl.obolibrary.org/obo/GO_0044058 regulation of digestive system process Any process that decreases the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism. http://purl.obolibrary.org/obo/UBERON_0003696 metatarsophalangeal joint http://purl.obolibrary.org/obo/UBERON_0001487 pes joint The metatarsophalangeal articulations are the joints between the metatarsal bones of the foot and the proximal bones of the toes . They are condyloid joints meaning an elliptical or rounded surface (of the metatarsal bones) come close to the shallow cavities (of the proximal phalanges). The ligaments are the plantar and two collateral. http://purl.obolibrary.org/obo/GO_0060458 right lung development http://purl.obolibrary.org/obo/GO_0030324 lung development The biological process whose specific outcome is the progression of a right lung from an initial condition to its mature state. This process begins with the formation of the right lung and ends with the mature structure. The right lung is the lung which is on the right side of the anterior posterior axis looking from a dorsal to ventral aspect. http://purl.obolibrary.org/obo/UBERON_0003697 abdominal wall http://purl.obolibrary.org/obo/UBERON_0000060 anatomical wall The tissues that surround the organs that are present within the abdominal cavity. The abdominal wall tissue is composed of layers of fat, parietal peritoneum, fascia, and muscles. http://purl.obolibrary.org/obo/GO_0060459 left lung development http://purl.obolibrary.org/obo/GO_0030324 lung development The biological process whose specific outcome is the progression of a left lung from an initial condition to its mature state. This process begins with the formation of the left lung and ends with the mature structure. The left lung is the lung which is on the left side of the anterior posterior axis looking from a dorsal to ventral aspect. http://purl.obolibrary.org/obo/UBERON_0003709 circle of Willis http://purl.obolibrary.org/obo/UBERON_0004573 systemic artery A circle of arteries that supply blood to the brain. The Circle of Willis comprises the following arteries: Anterior cerebral artery (left and right); Anterior communicating artery; Internal carotid artery (left and right); Posterior cerebral artery (left and right); Posterior communicating artery (left and right).The basilar artery and middle cerebral arteries, supplying the brain, are also considered part of the circle. http://purl.obolibrary.org/obo/GO_0060460 left lung morphogenesis http://purl.obolibrary.org/obo/GO_0060425 lung morphogenesis The process in which anatomical structures of the left lung are generated and organized. http://purl.obolibrary.org/obo/UBERON_0003711 brachiocephalic vein http://purl.obolibrary.org/obo/UBERON_0001638 vein The left and right brachiocephalic veins in the upper chest are formed by the union of each corresponding internal jugular vein and subclavian vein. This is at the level of the sternoclavicular joint. These great vessels merge to form the superior vena cava. The brachiocephalic veins are the major veins returning blood to the superior vena cava. http://purl.obolibrary.org/obo/GO_0060461 right lung morphogenesis http://purl.obolibrary.org/obo/GO_0060425 lung morphogenesis The process in which anatomical structures of the right lung are generated and organized. http://purl.obolibrary.org/obo/UBERON_0003713 splenic vein http://purl.obolibrary.org/obo/UBERON_0001638 vein A vein arising from the splenic trabecular vein in the hilum of the spleen that drains into the portal vein. http://purl.obolibrary.org/obo/UBERON_0003714 neural tissue http://purl.obolibrary.org/obo/UBERON_0000479 tissue Portion of tissue in the nervous system which consists of neurons and glial cells, and may also contain parts of the vasculature. http://purl.obolibrary.org/obo/GO_0060462 lung lobe development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The biological process whose specific outcome is the progression of a lung lobe from an initial condition to its mature state. This process begins with the formation of a lung lobe by branching morphogenesis and ends with the mature structure. A lung lobe is one of the rounded projections that compose the lung. http://purl.obolibrary.org/obo/UBERON_0003715 splanchnic nerve http://purl.obolibrary.org/obo/UBERON_0034729 sympathetic nerve The major nerves supplying sympathetic innervation to the abdomen, including the greater, lesser, and lowest (or smallest) splanchnic nerves that are formed by preganglionic fibers from the spinal cord which pass through the paravertebral ganglia and then to the celiac ganglia and plexuses and the lumbar splanchnic nerves carry fibers which pass through the lumbar paravertebral ganglia to the mesenteric and hypogastric ganglia. http://purl.obolibrary.org/obo/GO_0060463 lung lobe morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structures of a lung lobe are generated and organized. A lung lobe is a projection that extends from the lung. http://purl.obolibrary.org/obo/UBERON_0003716 recurrent laryngeal nerve http://purl.obolibrary.org/obo/UBERON_0011779 nerve of head region A branch of the vagus nerve that supplies motor function and sensation to the larynx (voice box). It travels within the endoneurium. It is the nerve of the 6th Branchial Arch. http://purl.obolibrary.org/obo/GO_0060464 lung lobe formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The developmental process pertaining to the initial formation of a lung lobe from unspecified parts. This process begins with the specific processes that contribute to the appearance of the lobe and ends when the structural rudiment is recognizable. A lung lobe is a projection that extends from the lung. http://purl.obolibrary.org/obo/GO_0060468 prevention of polyspermy http://purl.obolibrary.org/obo/GO_0060467 negative regulation of fertilization The negative regulation of fertilization process that takes place as part of egg activation, ensuring that only a single sperm fertilizes the egg. http://purl.obolibrary.org/obo/UBERON_0003718 muscle spindle http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure The sensory organs in muscle that are involved in the stretch reflex. http://purl.obolibrary.org/obo/GO_0060470 positive regulation of cytosolic calcium ion concentration involved in egg activation http://purl.obolibrary.org/obo/GO_0007204 positive regulation of cytosolic calcium ion concentration The process that increases the concentration of calcium ions in the cytosol after fertilization or the physiological activation of an egg. http://purl.obolibrary.org/obo/UBERON_0003721 lingual nerve http://purl.obolibrary.org/obo/UBERON_0011779 nerve of head region The lingual nerve is a branch of the mandibular nerve (CN V3), itself a branch of the trigeminal nerve, which supplies sensory innervation to the tongue. It also carries fibers from the facial nerve, which return taste information from the anterior two thirds of the tongue. http://purl.obolibrary.org/obo/GO_0060474 positive regulation of flagellated sperm motility involved in capacitation http://purl.obolibrary.org/obo/GO_1902093 positive regulation of flagellated sperm motility The process in which the controlled movement of a flagellated sperm cell is initiated as part of the process required for flagellated sperm to reach fertilization competence. http://purl.obolibrary.org/obo/UBERON_0003723 vestibular nerve http://purl.obolibrary.org/obo/UBERON_0011779 nerve of head region The vestibular nerve is one of the two branches of the Vestibulocochlear nerve (the cochlear nerve being the other). It goes to the semicircular canals via the vestibular ganglion. It receives positional information. Axons of the vestibular nerve synapse in the vestibular nucleus on the lateral floor and wall of the fourth ventricle in the pons and medulla. It arises from bipolar cells in the vestibular ganglion, ganglion of Scarpa, which is situated in the upper part of the outer end of the internal auditory meatus. [WP,unvetted]. http://purl.obolibrary.org/obo/GO_0060479 lung cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features of a mature cell found in the lung. Differentiation includes the processes involved in commitment of a cell to a specific fate. http://purl.obolibrary.org/obo/UBERON_0003726 thoracic nerve http://purl.obolibrary.org/obo/UBERON_0001780 spinal nerve The twelve spinal nerves on each side of the thorax. They include eleven INTERCOSTAL NERVES and one subcostal nerve. Both sensory and motor, they supply the muscles and skin of the thoracic and abdominal walls. http://purl.obolibrary.org/obo/GO_0060480 lung goblet cell differentiation http://purl.obolibrary.org/obo/GO_0061140 lung secretory cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a lung goblet cell. A goblet cell is a cell of the epithelial lining that produces and secretes mucins. http://purl.obolibrary.org/obo/UBERON_0003727 intercostal nerve http://purl.obolibrary.org/obo/UBERON_0001780 spinal nerve The intercostal nerves are the anterior divisions (rami anteriores; ventral divisions) of the thoracic spinal nerves from T1 to T11. Each nerve is connected with the adjoining ganglion of the sympathetic trunk by a gray and a white ramus communicans. The intercostal nerves are distributed chiefly to the thoracic pleura and abdominal peritoneum and differ from the anterior divisions of the other spinal nerves in that each pursues an independent course without plexus formation. The first two nerves supply fibers to the upper limb in addition to their thoracic branches; the next four are limited in their distribution to the parietes of the thorax; the lower five supply the parietes of the thorax and abdomen. The 7th intercostal nerve terminates at the xyphoid process, at the lower end of the sternum. The 10th intercostal nerve terminates at the umbilicus. The twelfth thoracic is distributed to the abdominal wall and groin. [WP,unvetted]. http://purl.obolibrary.org/obo/GO_0060481 lobar bronchus epithelium development http://purl.obolibrary.org/obo/GO_0060428 lung epithelium development The biological process whose specific outcome is the progression of a lobar bronchus epithelium from an initial condition to its mature state. This process begins with the formation of the lobar bronchus epithelium and ends with the mature structure. The lobar bronchus epithelium is the tissue made up of epithelial cells that lines the inside of the lobar bronchus. http://purl.obolibrary.org/obo/UBERON_0003729 mouth mucosa http://purl.obolibrary.org/obo/UBERON_0000344 mucosa A mucous membrane that lines the mouth. http://purl.obolibrary.org/obo/GO_0060482 lobar bronchus development http://purl.obolibrary.org/obo/GO_0060433 bronchus development The biological process whose specific outcome is the progression of a lobar bronchus from an initial condition to its mature state. This process begins with the formation of the lobar bronchus and ends with the mature structure. The lobar bronchus is the major airway within the respiratory tree that starts by division of the principal bronchi on both sides and ends at the point of its own subdivision into tertiary or segmental bronchi. http://purl.obolibrary.org/obo/UBERON_0003820 prostate bud http://purl.obolibrary.org/obo/UBERON_0005153 epithelial bud A region of the fetal urogenital sinus epithelium destined to become the prostate[GO]. http://purl.obolibrary.org/obo/GO_0060483 lobar bronchus mesenchyme development http://purl.obolibrary.org/obo/GO_0060484 lung-associated mesenchyme development The biological process whose specific outcome is the progression of a lobar bronchus mesenchyme from an initial condition to its mature state. This process begins with the formation of the lobar bronchus mesenchyme and ends with the mature structure. The lobar bronchus mesenchyme is the mass of tissue composed of mesenchymal cells in the lobar bronchus. http://purl.obolibrary.org/obo/UBERON_0003821 metapodium bone http://purl.obolibrary.org/obo/UBERON_0012357 digitopodium bone A bone of the metapodial skeleton. http://purl.obolibrary.org/obo/GO_0060484 lung-associated mesenchyme development http://purl.obolibrary.org/obo/GO_0060485 mesenchyme development The biological process whose specific outcome is the progression of a lung-associated mesenchyme from an initial condition to its mature state. This process begins with the formation of lung-associated mesenchyme and ends with the mature structure. Lung-associated mesenchyme is the tissue made up of loosely connected mesenchymal cells in the lung. http://purl.obolibrary.org/obo/UBERON_0003822 forelimb stylopod http://purl.obolibrary.org/obo/UBERON_0008785 upper limb segment The part of the forelimb between pectoral region and the elbow, corresponding to the humerus. http://purl.obolibrary.org/obo/GO_0060486 club cell differentiation http://purl.obolibrary.org/obo/GO_0060487 lung epithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a club cell. A club cell is an unciliated epithelial cell found in the respiratory and terminal bronchioles. http://purl.obolibrary.org/obo/UBERON_0003823 hindlimb zeugopod http://purl.obolibrary.org/obo/UBERON_0008784 lower limb segment The middle limb segment of the pelvic free limb, between the autopod and stylopod segments. Includes as parts the hindlimb zeugopodial skeleton, which includes as parts the tibia and fibula, or their cartilage precursors, or evolutionary variants. http://purl.obolibrary.org/obo/GO_0060487 lung epithelial cell differentiation http://purl.obolibrary.org/obo/GO_0060479 lung cell differentiation The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell that contributes to the epithelium of the lung. http://purl.obolibrary.org/obo/UBERON_0003824 nerve of thoracic segment http://purl.obolibrary.org/obo/UBERON_0003439 nerve of trunk region A nerve that is part of a thorax [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060490 lateral sprouting involved in lung morphogenesis http://purl.obolibrary.org/obo/GO_0060601 lateral sprouting from an epithelium The process in which a branch forms along the side of the lung epithelial tube. http://purl.obolibrary.org/obo/UBERON_0003825 nerve of abdominal segment http://purl.obolibrary.org/obo/UBERON_0003439 nerve of trunk region A nerve that is part of an abdominal segment of trunk [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060496 mesenchymal-epithelial cell signaling involved in lung development http://purl.obolibrary.org/obo/GO_0060638 mesenchymal-epithelial cell signaling Any process that mediates the transfer of information from a mesenchymal cell to an epithelial cell and contributes to the development of the lung. http://purl.obolibrary.org/obo/UBERON_0003826 upper leg bone http://purl.obolibrary.org/obo/UBERON_0005893 leg bone A bone that is part of a hindlimb stylopod [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060497 mesenchymal-endodermal cell signaling http://purl.obolibrary.org/obo/GO_0007267 cell-cell signaling Any process that mediates the transfer of information between a mesenchymal cell and an endodermal cell. http://purl.obolibrary.org/obo/UBERON_0003827 thoracic segment bone http://purl.obolibrary.org/obo/UBERON_0005181 thoracic segment organ A bone that is part of a thorax [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis http://purl.obolibrary.org/obo/GO_2000794 regulation of epithelial cell proliferation involved in lung morphogenesis Any process that increases the rate or frequency of epithelial cell proliferation that results in the lung attaining its shape. http://purl.obolibrary.org/obo/UBERON_0003828 abdominal segment bone http://purl.obolibrary.org/obo/UBERON_0005173 abdominal segment element A bone that is part of an abdominal segment of trunk [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060502 epithelial cell proliferation involved in lung morphogenesis http://purl.obolibrary.org/obo/GO_0050673 epithelial cell proliferation The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population that contributes to the shaping of the lung. http://purl.obolibrary.org/obo/UBERON_0003829 urethra muscle tissue http://purl.obolibrary.org/obo/UBERON_0005090 muscle structure Any muscle tissue that is part of the urethra. http://purl.obolibrary.org/obo/GO_0060509 type I pneumocyte differentiation http://purl.obolibrary.org/obo/GO_0060487 lung epithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a type I pneumocyte. A type I pneumocyte is a flattened cell with greatly attenuated cytoplasm and a paucity of organelles. http://purl.obolibrary.org/obo/UBERON_0003830 thoracic segment muscle http://purl.obolibrary.org/obo/UBERON_0005181 thoracic segment organ Any muscle organ that is part of a thorax [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060510 type II pneumocyte differentiation http://purl.obolibrary.org/obo/GO_0061140 lung secretory cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a type II pneumocyte. A type II pneumocyte is a surfactant secreting cell that contains abundant cytoplasm containing numerous lipid-rich multilamellar bodies. http://purl.obolibrary.org/obo/UBERON_0003831 respiratory system muscle http://purl.obolibrary.org/obo/UBERON_0001630 muscle organ Any muscle organ that is part of a respiratory system [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060512 prostate gland morphogenesis http://purl.obolibrary.org/obo/GO_0003006 developmental process involved in reproduction The process in which the anatomical structures of a prostate gland are generated and organized. http://purl.obolibrary.org/obo/UBERON_0003832 esophagus muscle http://purl.obolibrary.org/obo/UBERON_0013765 digestive system element Any muscle organ that is part of a esophagus [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060513 prostatic bud formation http://purl.obolibrary.org/obo/GO_0060740 prostate gland epithelium morphogenesis The morphogenetic process in which a region of the fetal urogenital sinus epithelium is specified to become the prostate, resulting in prostate bud outgrowth. http://purl.obolibrary.org/obo/UBERON_0003833 abdominal segment muscle http://purl.obolibrary.org/obo/UBERON_0005173 abdominal segment element A muscle organ that is part of an abdominal segment of trunk [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060525 prostate glandular acinus development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of a glandular acinus of the prostate gland over time, from its initial formation to the mature structure. The glandular acini are the saclike structures of the gland. http://purl.obolibrary.org/obo/UBERON_0003834 thoracic segment blood vessel http://purl.obolibrary.org/obo/UBERON_0003513 trunk blood vessel A blood vessel that is part of a thorax [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060526 prostate glandular acinus morphogenesis http://purl.obolibrary.org/obo/GO_0060740 prostate gland epithelium morphogenesis The process in which the prostate glandular acini are generated and organized. The glandular acini are the saclike structures of the gland. http://purl.obolibrary.org/obo/UBERON_0003835 abdominal segment blood vessel http://purl.obolibrary.org/obo/UBERON_0003513 trunk blood vessel A blood vessel that is part of an abdominal segment of trunk [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060532 bronchus cartilage development http://purl.obolibrary.org/obo/GO_0051216 cartilage development The process whose specific outcome is the progression of lung cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate. http://purl.obolibrary.org/obo/UBERON_0003836 abdominal segment skin http://purl.obolibrary.org/obo/UBERON_0001085 skin of trunk A skin of body that is part of an abdominal segment of trunk [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060533 bronchus cartilage morphogenesis http://purl.obolibrary.org/obo/GO_0060536 cartilage morphogenesis The process in which the bronchus cartilage is generated and organized. The bronchus cartilage is the connective tissue of the portion of the airway that connects to the lungs. http://purl.obolibrary.org/obo/GO_0060534 trachea cartilage development http://purl.obolibrary.org/obo/GO_0051216 cartilage development The process whose specific outcome is the progression of the tracheal cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate. http://purl.obolibrary.org/obo/UBERON_0003837 thoracic segment connective tissue http://purl.obolibrary.org/obo/UBERON_0003586 trunk connective tissue A portion of connective tissue that is part of a thorax [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060535 trachea cartilage morphogenesis http://purl.obolibrary.org/obo/GO_0060536 cartilage morphogenesis The process in which the anatomical structures of cartilage in the trachea are generated and organized. http://purl.obolibrary.org/obo/UBERON_0003838 abdominal segment connective tissue http://purl.obolibrary.org/obo/UBERON_0003586 trunk connective tissue A portion of connective tissue that is part of an abdominal segment of trunk [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060539 diaphragm development http://purl.obolibrary.org/obo/GO_0060538 skeletal muscle organ development The progression of the diaphragm over time from its initial formation to the mature structure. The diaphragm is a skeletal muscle that is responsible for contraction and expansion of the lungs. http://purl.obolibrary.org/obo/UBERON_0003839 forelimb joint http://purl.obolibrary.org/obo/UBERON_0003657 limb joint A limb joint that is part of a forelimb [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060540 diaphragm morphogenesis http://purl.obolibrary.org/obo/GO_0048644 muscle organ morphogenesis The process in which the anatomical structures of the diaphragm are generated and organized. http://purl.obolibrary.org/obo/UBERON_0003840 hindlimb joint http://purl.obolibrary.org/obo/UBERON_0003657 limb joint A limb joint that is part of a hindlimb [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060568 regulation of peptide hormone processing http://purl.obolibrary.org/obo/GO_0070613 regulation of protein processing Any process that modulates the rate, frequency or extent of peptide hormone processing. Peptide hormone processing is the generation of a mature peptide hormone by posttranslational processing of a prohormone. http://purl.obolibrary.org/obo/UBERON_0003841 autopod joint http://purl.obolibrary.org/obo/UBERON_0003657 limb joint A limb joint that is part of an autopod [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060569 positive regulation of peptide hormone processing http://purl.obolibrary.org/obo/GO_0060568 regulation of peptide hormone processing Any process that increases the rate, frequency or extent of peptide hormone processing. Peptide hormone processing is the generation of a mature peptide hormone by posttranslational processing of a prohormone. http://purl.obolibrary.org/obo/UBERON_0003842 neural tube lumen http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space An anatomical space that surrounded_by a neural tube. http://purl.obolibrary.org/obo/GO_0060570 negative regulation of peptide hormone processing http://purl.obolibrary.org/obo/GO_0060568 regulation of peptide hormone processing Any process that decreases the rate, frequency or extent of peptide hormone processing. Peptide hormone processing is the generation of a mature peptide hormone by posttranslational processing of a prohormone. http://purl.obolibrary.org/obo/UBERON_0003843 dental epithelium http://purl.obolibrary.org/obo/UBERON_0000483 epithelium Epithelium that is part of a developing tooth or dental organ. http://purl.obolibrary.org/obo/GO_0060572 morphogenesis of an epithelial bud http://purl.obolibrary.org/obo/GO_0060571 morphogenesis of an epithelial fold The morphogenetic process in which a bud forms from an epithelial sheet. A bud is a protrusion that forms form the sheet by localized folding. http://purl.obolibrary.org/obo/UBERON_0003846 thymus epithelium http://purl.obolibrary.org/obo/UBERON_0000483 epithelium An epithelium that is part of a thymus, forming a supporting framework[MP,modified]. http://purl.obolibrary.org/obo/GO_0060574 intestinal epithelial cell maturation http://purl.obolibrary.org/obo/GO_0002069 columnar/cuboidal epithelial cell maturation The developmental process, independent of morphogenetic (shape) change, that is required for a columna/cuboidal epithelial cell of the intestine to attain its fully functional state. A columnar/cuboidal epithelial cell of the intestine mature as they migrate from the intestinal crypt to the villus. http://purl.obolibrary.org/obo/GO_0060575 intestinal epithelial cell differentiation http://purl.obolibrary.org/obo/GO_0002065 columnar/cuboidal epithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a columnar/cuboidal epithelial cell of the intestine. http://purl.obolibrary.org/obo/GO_0060576 intestinal epithelial cell development http://purl.obolibrary.org/obo/GO_0002066 columnar/cuboidal epithelial cell development The process whose specific outcome is the progression of a columnar/cuboidal epithelial cell of the intestine over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0060577 pulmonary vein morphogenesis http://purl.obolibrary.org/obo/GO_0048845 venous blood vessel morphogenesis The process in which the anatomical structure of the pulmonary venous blood vessels are generated and organized. Pulmonary veins are blood vessels that transport blood from the lungs to the heart. http://purl.obolibrary.org/obo/GO_0060578 superior vena cava morphogenesis http://purl.obolibrary.org/obo/GO_0048845 venous blood vessel morphogenesis The process in which the anatomical structure of superior vena cava generated and organized. The superior vena cava is a blood vessel that transports blood from the upper body to the heart. http://purl.obolibrary.org/obo/GO_0060586 multicellular organismal-level iron ion homeostasis http://purl.obolibrary.org/obo/GO_0140962 multicellular organismal-level chemical homeostasis A chemical homeostatic process involved in the maintenance of a steady state level of iron within extracellular body fluids, such as blood, xylem or phloem, of a multicellular organism. This is distinct from maintenance of cellular homeostasis, which occurs within a cell. http://purl.obolibrary.org/obo/GO_0060591 chondroblast differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a mesenchymal cell, acquires specialized structural and/or functional features of a chondroblast. Differentiation includes the processes involved in commitment of a cell to a chondroblast fate. A chondroblast is a precursor cell to chondrocytes. http://purl.obolibrary.org/obo/GO_0060592 mammary gland formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process pertaining to the initial formation of the mammary gland from unspecified parts. The process begins with formation of the mammary line and ends when the solid mammary bud invades the primary mammary mesenchyme. http://purl.obolibrary.org/obo/GO_0060596 mammary placode formation http://purl.obolibrary.org/obo/GO_0060788 ectodermal placode formation The developmental process in which the mammary placode forms. The mammary placode is a transient lens shaped structure that will give rise to the mammary bud proper. http://purl.obolibrary.org/obo/GO_0060599 lateral sprouting involved in mammary gland duct morphogenesis http://purl.obolibrary.org/obo/GO_0060601 lateral sprouting from an epithelium The process in which a branch forms along the side of a mammary duct. http://purl.obolibrary.org/obo/GO_0060601 lateral sprouting from an epithelium http://purl.obolibrary.org/obo/GO_0002009 morphogenesis of an epithelium The process in which a branch forms along the side of an epithelium. http://purl.obolibrary.org/obo/UBERON_0003847 thyroid artery http://purl.obolibrary.org/obo/UBERON_0001637 artery An artery that supplies a thyroid gland. http://purl.obolibrary.org/obo/GO_0060603 mammary gland duct morphogenesis http://purl.obolibrary.org/obo/GO_0060562 epithelial tube morphogenesis The process in which anatomical structures of the mammary ducts are generated and organized. Mammary ducts are epithelial tubes that transport milk. http://purl.obolibrary.org/obo/UBERON_0003848 gonadal vein http://purl.obolibrary.org/obo/UBERON_0001638 vein In medicine, gonadal vein refers to the blood vessel that carrying blood away from the gonad (testis, ovary) toward the heart. Females : ovarian vein Males : testicular vein [WP,unvetted]. http://purl.obolibrary.org/obo/GO_0060611 mammary gland fat development http://purl.obolibrary.org/obo/GO_0060612 adipose tissue development The progression of the mammary gland fat over time, from its formation to the mature structure. The mammary fat is an adipose structure in the gland that is invaded by the mammary ducts. http://purl.obolibrary.org/obo/UBERON_0003849 mesencephalic neural crest http://purl.obolibrary.org/obo/UBERON_0003099 cranial neural crest A neural crest that has_potential_to_developmentally_contribute_to a midbrain. http://purl.obolibrary.org/obo/GO_0060615 mammary gland bud formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The morphogenetic process in which a bud forms from the mammary placode. A mammary bud is bulb of epithelial cells that is distinct from the surrounding epidermis. http://purl.obolibrary.org/obo/UBERON_0003850 telencephalon neural crest http://purl.obolibrary.org/obo/UBERON_0002342 neural crest A neural crest that has_potential_to_developmentally_contribute_to a telencephalon. http://purl.obolibrary.org/obo/GO_0060616 mammary gland cord formation http://purl.obolibrary.org/obo/GO_0072175 epithelial tube formation The process in which the mammary gland cord forms by elongation of the mammary bud. The cord is formed once the elongating bud breaks through the mesenchyme and reaches the fat pad. http://purl.obolibrary.org/obo/UBERON_0003851 diencephalon neural crest http://purl.obolibrary.org/obo/UBERON_0002342 neural crest A neural crest that has_potential_to_developmentally_contribute_to a diencephalon. http://purl.obolibrary.org/obo/GO_0060618 nipple development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the nipple over time, from its formation to the mature structure. The nipple is a part of the mammary gland that protrudes from the surface ectoderm. http://purl.obolibrary.org/obo/UBERON_0003852 rhombencephalon neural crest http://purl.obolibrary.org/obo/UBERON_0003099 cranial neural crest A neural crest that has_potential_to_developmentally_contribute_to a hindbrain. http://purl.obolibrary.org/obo/GO_0060623 regulation of chromosome condensation http://purl.obolibrary.org/obo/GO_0033044 regulation of chromosome organization Any process that modulates the rate, frequency, or extent of chromosome condensation, the progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells. http://purl.obolibrary.org/obo/UBERON_0003853 spinal cord neural crest http://purl.obolibrary.org/obo/UBERON_0002342 neural crest A neural crest that has_potential_to_developmentally_contribute_to a spinal cord. http://purl.obolibrary.org/obo/GO_0060638 mesenchymal-epithelial cell signaling http://purl.obolibrary.org/obo/GO_0007267 cell-cell signaling Any process that mediates the transfer of information from a mesenchymal cell to an epithelial cell where it is received and interpreted. http://purl.obolibrary.org/obo/UBERON_0003854 spinal cord neural plate http://purl.obolibrary.org/obo/UBERON_0003075 neural plate A neural plate that develops_from a future spinal cord. http://purl.obolibrary.org/obo/GO_0060644 mammary gland epithelial cell differentiation http://purl.obolibrary.org/obo/GO_0030855 epithelial cell differentiation The process in which a relatively unspecialized epithelial cell becomes a more specialized epithelial cell of the mammary gland. http://purl.obolibrary.org/obo/UBERON_0003855 gonad mesenchyme http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure Mesenchyme that is part of a developing gonad [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060648 mammary gland bud morphogenesis http://purl.obolibrary.org/obo/GO_0060572 morphogenesis of an epithelial bud The process in which anatomical structures of the mammary gland buds are generated and organized. Mammary gland buds form by an outpocketing of the mammary placodes and grow to invade the mammary fat, when they form the mammary cord. http://purl.obolibrary.org/obo/UBERON_0003856 uncondensed odontogenic mesenchyme http://purl.obolibrary.org/obo/UBERON_0007529 loose mesenchyme tissue Mesenchyme enclosed by a dental organ that gives rise to an odontogenic papilla. http://purl.obolibrary.org/obo/GO_0060652 mammary gland cord morphogenesis http://purl.obolibrary.org/obo/GO_0060562 epithelial tube morphogenesis The process in which anatomical structures of the mammary gland cord are generated and organized. Mammary gland cords form when the mammary gland bud invades the mammary fat. http://purl.obolibrary.org/obo/UBERON_0003859 forelimb mesenchyme http://purl.obolibrary.org/obo/UBERON_0009749 limb mesenchyme Mesenchyme that is part of a developing forelimb [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060658 nipple morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the nipple is generated and organized. http://purl.obolibrary.org/obo/UBERON_0003860 hindlimb mesenchyme http://purl.obolibrary.org/obo/UBERON_0009749 limb mesenchyme Mesenchyme that is part of a developing hindlimb [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060661 submandibular salivary gland formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The developmental process pertaining to the initial formation of a submandibular salivary gland. This process begins with a thickening of the epithelium next to the tongue and ends when a bud linked to the oral surface is formed. http://purl.obolibrary.org/obo/UBERON_0003861 neural arch http://purl.obolibrary.org/obo/UBERON_0010358 arch of centrum of vertebra Posterior part of a vertebra that consists of a pair of pedicles and a pair of laminae, and supports seven processes: four articular processes, two transverse processes one spinous process[WP]. ZFA: A neural arch encloses the neural canal and typically meets its partner to form a neural spine. http://purl.obolibrary.org/obo/GO_0060664 epithelial cell proliferation involved in salivary gland morphogenesis http://purl.obolibrary.org/obo/GO_0050673 epithelial cell proliferation The multiplication or reproduction of epithelial cells of the submandibular salivary gland, resulting in the expansion of a cell population and the shaping of the gland. http://purl.obolibrary.org/obo/UBERON_0003864 middle phalanx of manus http://purl.obolibrary.org/obo/UBERON_0004301 middle phalanx A middle phalanx that is part of a finger [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060669 embryonic placenta morphogenesis http://purl.obolibrary.org/obo/GO_0048598 embryonic morphogenesis The process in which the embryonic placenta is generated and organized. http://purl.obolibrary.org/obo/UBERON_0003865 distal phalanx of manus http://purl.obolibrary.org/obo/UBERON_0004300 distal phalanx A distal phalanx that is part of a finger [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060670 branching involved in labyrinthine layer morphogenesis http://purl.obolibrary.org/obo/GO_0048598 embryonic morphogenesis The process in which the branches of the fetal placental villi are generated and organized. The villous part of the placenta is called the labyrinth layer. http://purl.obolibrary.org/obo/UBERON_0003866 middle phalanx of pes http://purl.obolibrary.org/obo/UBERON_0004301 middle phalanx A middle phalanx that is part of a toe [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060671 epithelial cell differentiation involved in embryonic placenta development http://purl.obolibrary.org/obo/GO_0060706 cell differentiation involved in embryonic placenta development The process in which a trophoblast cell acquires specialized features of an epithelial cell of the placental labyrinthine layer. http://purl.obolibrary.org/obo/GO_0060674 placenta blood vessel development http://purl.obolibrary.org/obo/GO_0001568 blood vessel development The process whose specific outcome is the progression of a blood vessel of the placenta over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/UBERON_0003867 distal phalanx of pes http://purl.obolibrary.org/obo/UBERON_0004300 distal phalanx A distal phalanx that is part of a pedal digit [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060676 ureteric bud formation http://purl.obolibrary.org/obo/GO_0072172 mesonephric tubule formation The developmental process pertaining to the initial formation of the ureteric bud from the Wolffian duct. This process begins when the bud protrudes from the duct and ends when it is a recognizable bud. http://purl.obolibrary.org/obo/UBERON_0003868 proximal phalanx of pes http://purl.obolibrary.org/obo/UBERON_0004302 proximal phalanx A proximal phalanx that is part of a pedal digit [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060684 epithelial-mesenchymal cell signaling http://purl.obolibrary.org/obo/GO_0007267 cell-cell signaling Any process that results in the transfer of information from an epithelial cell to a mesenchymal cell where it is interpreted. http://purl.obolibrary.org/obo/UBERON_0003869 presumptive ganglion http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure A presumptive structure that has the potential to develop into a ganglion. http://purl.obolibrary.org/obo/GO_0060685 regulation of prostatic bud formation http://purl.obolibrary.org/obo/GO_0060688 regulation of morphogenesis of a branching structure Any process that modulates the rate, frequency, or extent of prostatic bud formation, the morphogenetic process in which a region of the fetal urogenital sinus epithelium is specified to become the prostate, resulting in prostate bud outgrowth. http://purl.obolibrary.org/obo/UBERON_0003876 hippocampal field http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain A part or parts of the hippocampus that have a particular function. http://purl.obolibrary.org/obo/GO_0060686 negative regulation of prostatic bud formation http://purl.obolibrary.org/obo/GO_0060685 regulation of prostatic bud formation Any process that decreases the rate, frequency, or extent of prostatic bud formation, the morphogenetic process in which a region of the fetal urogenital sinus epithelium is specified to become the prostate, resulting in prostate bud outgrowth. http://purl.obolibrary.org/obo/UBERON_0003883 CA3 field of hippocampus http://purl.obolibrary.org/obo/UBERON_0003876 hippocampal field Part of hippocampus proper bounded by the hilus of the dentate gyrus and area CA2, characterized by large pyramidal cells and a dense projection from dentate gyrus granule cell mossy fibers. http://purl.obolibrary.org/obo/GO_0060687 regulation of branching involved in prostate gland morphogenesis http://purl.obolibrary.org/obo/GO_0060688 regulation of morphogenesis of a branching structure Any process that modulates the rate, frequency, or extent of prostate gland branching, the process in which the branching structure of the prostate gland is generated and organized. A branch is a division or offshoot from a main stem. http://purl.obolibrary.org/obo/UBERON_0003884 CA4 field of hippocampus http://purl.obolibrary.org/obo/UBERON_0003876 hippocampal field The last of four regions in the cornu ammonis of the hippocampus and is also part of the hilus of the dentate gyrus. This area contains mostly mossy cells that receive inputs from the dentate gyrus and pyramidal cells in the CA3 region and also projects back to the dentate gyrus. http://purl.obolibrary.org/obo/GO_0060688 regulation of morphogenesis of a branching structure http://purl.obolibrary.org/obo/GO_0051239 regulation of multicellular organismal process Any process that modulates the rate, frequency, or extent of branching morphogenesis, the process in which the anatomical structures of branches are generated and organized. http://purl.obolibrary.org/obo/UBERON_0003885 mesometrium http://purl.obolibrary.org/obo/UBERON_0002095 mesentery A mesentery that is part of a uterus [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060689 cell differentiation involved in salivary gland development http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires specialized structural and/or functional features that characterize the cells of the salivary gland. http://purl.obolibrary.org/obo/UBERON_0003886 future coelemic cavity lumen http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space An anatomical cavity that has the potential to develop into a coelemic cavity lumen. http://purl.obolibrary.org/obo/GO_0060690 epithelial cell differentiation involved in salivary gland development http://purl.obolibrary.org/obo/GO_0060689 cell differentiation involved in salivary gland development The process in which a relatively unspecialized cell acquire specialized structural and/or functional features of an epithelial cell of the salivary gland. http://purl.obolibrary.org/obo/UBERON_0003887 intraembryonic coelom http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure The part of the coelom in the embryo between the somatopleuric and splanchnopleuric mesoderm; the principal body cavities of the trunk (thoracic, abdominal, and pelvic) arise from this embryonic part of the coelom. http://purl.obolibrary.org/obo/GO_0060691 epithelial cell maturation involved in salivary gland development http://purl.obolibrary.org/obo/GO_0002070 epithelial cell maturation The developmental process, independent of morphogenetic (shape) change, that is required for an epithelial cell of the salivary gland to attain its fully functional state. http://purl.obolibrary.org/obo/UBERON_0003890 Mullerian duct http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure Paired ducts of the embryo that run down the lateral sides of the urogenital ridge and terminate at the mullerian eminence in the primitive urogenital sinus. In the female, they will develop to form the fallopian tubes, uterus, and the upper portion of the vagina; in the male, they are lost. These ducts are made of tissue of mesodermal origin[WP]. develops either by lengthwise splitting of the archinephric duct (in chondrichthyans and some amphibians) or by a elongated invagination of the coelomic epithelium (other vertebrates) In males, the oviducts regress. The cranial end of the oviduct maintains an opening into the coelom (which primitively may have been the anteriormost coelomic funnels connecting the nephrocoel with the coelom). This opening is the ostium tubae[USM]. http://purl.obolibrary.org/obo/GO_0060693 regulation of branching involved in salivary gland morphogenesis http://purl.obolibrary.org/obo/GO_0060688 regulation of morphogenesis of a branching structure Any process that modulates the rate, frequency, or extent of branching morphogenesis in the salivary gland epithelium. http://purl.obolibrary.org/obo/UBERON_0003891 stroma http://purl.obolibrary.org/obo/UBERON_0000064 organ part Connective, non-functional supportive framework of a biological cell, tissue, or organ. Contrast with parenchyma. http://purl.obolibrary.org/obo/UBERON_0003893 capsule http://purl.obolibrary.org/obo/UBERON_0000158 membranous layer A cover or envelope partly or wholly surrounding a structure. Examples: egg shell, articular capsules, renal capsules[WP]. http://purl.obolibrary.org/obo/GO_0060706 cell differentiation involved in embryonic placenta development http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires specialized features of the embryonic placenta. http://purl.obolibrary.org/obo/UBERON_0003894 liver primordium http://purl.obolibrary.org/obo/UBERON_0009497 epithelium of foregut-midgut junction A small endodermal thickening in the foregut adjacent to the transverse septum. Invaginates forming the hepatic diverticulum. http://purl.obolibrary.org/obo/GO_0060707 trophoblast giant cell differentiation http://purl.obolibrary.org/obo/GO_0060706 cell differentiation involved in embryonic placenta development The process in which a relatively unspecialized cell acquires specialized features of a trophoblast giant cell of the placenta. Trophoblast giant cells are the cell of the placenta that line the maternal decidua. http://purl.obolibrary.org/obo/UBERON_0003897 axial muscle http://purl.obolibrary.org/obo/UBERON_0014892 skeletal muscle organ, vertebrate One of the skeletal muscles of the head and neck, spine, and ribs. http://purl.obolibrary.org/obo/GO_0060708 spongiotrophoblast differentiation http://purl.obolibrary.org/obo/GO_0060706 cell differentiation involved in embryonic placenta development The process in which a relatively unspecialized cell of the ectoplacental cone acquires specialized features of a spongiotrophoblast of the placenta. A spongiotrophoblast cell is a basophilic cell. http://purl.obolibrary.org/obo/UBERON_0003898 skeletal muscle tissue of trunk http://purl.obolibrary.org/obo/UBERON_0001134 skeletal muscle tissue A portion of skeletal muscle tissue in the trunk. http://purl.obolibrary.org/obo/GO_0060711 labyrinthine layer development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process in which the labyrinthine layer of the placenta progresses, from its formation to its mature state. http://purl.obolibrary.org/obo/UBERON_0003902 retinal neural layer http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure The part of the retina that contains neurons and photoreceptor cells[GO]. http://purl.obolibrary.org/obo/GO_0060712 spongiotrophoblast layer development http://purl.obolibrary.org/obo/GO_0009888 tissue development The process in which the spongiotrophoblast layer of the placenta progresses from its formation to its mature state. http://purl.obolibrary.org/obo/UBERON_0003909 sinusoid http://purl.obolibrary.org/obo/UBERON_2005260 fenestrated capillary Small blood vessel similar to a capillary but with a fenestrated endothelium. Sinusoids are found in the liver, lymphoid tissue, endocrine organs, and hematopoietic organs such as the bone marrow and the spleen. Sinusoids found within terminal villi of the placenta are not comparable to these; they possess a continuous endothelium and complete basal lamina[WP]. http://purl.obolibrary.org/obo/GO_0060713 labyrinthine layer morphogenesis http://purl.obolibrary.org/obo/GO_0048598 embryonic morphogenesis The process in which the labyrinthine layer of the placenta is generated and organized. http://purl.obolibrary.org/obo/UBERON_0003910 splenic sinusoid http://purl.obolibrary.org/obo/UBERON_0003909 sinusoid Wide vessels in the spleen that drain into trabecular veins[WP]. http://purl.obolibrary.org/obo/GO_0060714 labyrinthine layer formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The developmental process pertaining to the initial formation of the labyrinthine layer of the placenta. http://purl.obolibrary.org/obo/UBERON_0003911 choroid plexus epithelium http://purl.obolibrary.org/obo/UBERON_0000483 epithelium The epithelial component of the choroid plexus. Consists of cuboidal epithelial cells surrounding a core of capillaries and loose connective tissue. http://purl.obolibrary.org/obo/GO_0060716 labyrinthine layer blood vessel development http://purl.obolibrary.org/obo/GO_0060674 placenta blood vessel development The process whose specific outcome is the progression of a blood vessel of the labyrinthine layer of the placenta over time, from its formation to the mature structure. The embryonic vessels grow through the layer to come in close contact with the maternal blood supply. http://purl.obolibrary.org/obo/UBERON_0003913 tooth-like structure http://purl.obolibrary.org/obo/UBERON_0004765 skeletal element Hard bony, calcareous, or chitinous organ found in the mouth or pharynx of an animal and used in procuring or masticating food. http://purl.obolibrary.org/obo/GO_0060717 chorion development http://purl.obolibrary.org/obo/GO_1903867 extraembryonic membrane development The biological process whose specific outcome is the progression of a chorion from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The chorion is an extraembryonic membrane. http://purl.obolibrary.org/obo/GO_0060718 chorionic trophoblast cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which relatively unspecialized cells of the ectoplacental cone acquire specialized structural and/or functional features that characterize chorionic trophoblasts. These cells will migrate towards the spongiotrophoblast layer and give rise to syncytiotrophoblasts of the labyrinthine layer. http://purl.obolibrary.org/obo/UBERON_0003914 epithelial tube http://purl.obolibrary.org/obo/UBERON_0000483 epithelium Epithelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system. http://purl.obolibrary.org/obo/GO_0060719 chorionic trophoblast cell development http://purl.obolibrary.org/obo/GO_0048468 cell development The process whose specific outcome is the progression of the chorionic trophoblast over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. http://purl.obolibrary.org/obo/UBERON_0003915 endothelial tube http://purl.obolibrary.org/obo/UBERON_0003914 epithelial tube Any endothelium that has the quality of being cylindrical [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060722 cell proliferation involved in embryonic placenta development http://purl.obolibrary.org/obo/GO_0008283 cell population proliferation The multiplication or reproduction of cells, resulting in the expansion of the population in the embryonic placenta. http://purl.obolibrary.org/obo/UBERON_0003918 kidney mesenchyme http://purl.obolibrary.org/obo/UBERON_0003104 mesenchyme Kidney mesenchyme is the tissue made up of loosely connected mesenchymal cells in the kidney[GO]. http://purl.obolibrary.org/obo/GO_0060723 regulation of cell proliferation involved in embryonic placenta development http://purl.obolibrary.org/obo/GO_0042127 regulation of cell population proliferation Any process that modulates the rate, frequency, or extent of cell proliferation involved in embryonic placenta development. http://purl.obolibrary.org/obo/UBERON_0003920 venous blood vessel http://purl.obolibrary.org/obo/UBERON_0001981 blood vessel A blood vessel that carries blood from the capillaries toward the heart. http://purl.obolibrary.org/obo/GO_0060736 prostate gland growth http://purl.obolibrary.org/obo/GO_0003006 developmental process involved in reproduction The increase in size or mass of the prostate gland where the increase in size or mass has the specific outcome of the progression of the gland, from its formation to its mature state. http://purl.obolibrary.org/obo/UBERON_0003921 pancreas primordium http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure Embryonic structure that develops into pancreatic bud. http://purl.obolibrary.org/obo/UBERON_0003922 pancreatic epithelial bud http://purl.obolibrary.org/obo/UBERON_0007499 epithelial sac The embryonic pancreas develops from two separate anlagen in the foregut epithelium, one dorsal and two ventral pancreatic buds[PMID]. http://purl.obolibrary.org/obo/GO_0060737 prostate gland morphogenetic growth http://purl.obolibrary.org/obo/GO_0060736 prostate gland growth The differential increase in size or mass of the prostate gland that contributes to the gland attaining its form. http://purl.obolibrary.org/obo/UBERON_0003923 dorsal pancreatic bud http://purl.obolibrary.org/obo/UBERON_0003922 pancreatic epithelial bud Pancreatic bud that gives rise to the accessory pancreatic duct. http://purl.obolibrary.org/obo/GO_0060738 epithelial-mesenchymal signaling involved in prostate gland development http://purl.obolibrary.org/obo/GO_0060684 epithelial-mesenchymal cell signaling Any process that results in the transfer of information from an epithelial cell to a mesenchymal cell where it is interpreted and contributes to the progression of the prostate gland over time. http://purl.obolibrary.org/obo/UBERON_0003924 ventral pancreatic bud http://purl.obolibrary.org/obo/UBERON_0003922 pancreatic epithelial bud Pancreatic bud that gives rise to the major pancreatic duct. http://purl.obolibrary.org/obo/GO_0060739 mesenchymal-epithelial cell signaling involved in prostate gland development http://purl.obolibrary.org/obo/GO_0060638 mesenchymal-epithelial cell signaling Any process that mediates the transfer of information from a mesenchymal cell to an epithelial cell where it is received and interpreted contributing to the progression of the prostate gland over time. http://purl.obolibrary.org/obo/UBERON_0003928 digestive system duct http://purl.obolibrary.org/obo/UBERON_0000058 duct A duct that is part of a digestive system [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060740 prostate gland epithelium morphogenesis http://purl.obolibrary.org/obo/GO_0003006 developmental process involved in reproduction The process in which the anatomical structures of epithelia of the prostate gland are generated and organized. An epithelium consists of closely packed cells arranged in one or more layers, that covers the outer surfaces of the body or lines any internal cavity or tube. http://purl.obolibrary.org/obo/UBERON_0003929 digestive tract epithelium http://purl.obolibrary.org/obo/UBERON_0000483 epithelium An epithelium that lines the lumen of the digestive tract. http://purl.obolibrary.org/obo/GO_0060741 prostate gland stromal morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the prostate gland stroma is generated and organized. The prostate gland stroma is made up of the mesenchymal or fibroblast cells of the prostate gland. http://purl.obolibrary.org/obo/UBERON_0003931 diencephalic white matter http://purl.obolibrary.org/obo/UBERON_0019261 white matter of forebrain White matter that is part of a diencephalon [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0060742 epithelial cell differentiation involved in prostate gland development http://purl.obolibrary.org/obo/GO_0030855 epithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell of the prostate gland. http://purl.obolibrary.org/obo/UBERON_0003932 cartilage element of chondrocranium http://purl.obolibrary.org/obo/UBERON_0003933 cranial cartilage A cartilage element of chondrocranium. Example: neurocranial trabecula. http://purl.obolibrary.org/obo/GO_0060743 epithelial cell maturation involved in prostate gland development http://purl.obolibrary.org/obo/GO_0002070 epithelial cell maturation The developmental process, independent of morphogenetic (shape) change, that is required for an epithelial cell of the prostate gland to attain its fully functional state. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface. http://purl.obolibrary.org/obo/UBERON_0003933 cranial cartilage http://purl.obolibrary.org/obo/UBERON_0007844 cartilage element A cartilage element that is part of the cranial skeleton. http://purl.obolibrary.org/obo/GO_0060749 mammary gland alveolus development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the mammary gland alveolus over time, from its formation to its mature state. The mammary gland alveolus is a sac-like structure that is found in the mature gland. http://purl.obolibrary.org/obo/UBERON_0003937 reproductive gland http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure Any of the organized aggregations of cells that function as secretory or excretory organs and are associated with reproduction. http://purl.obolibrary.org/obo/GO_0060753 regulation of mast cell chemotaxis http://purl.obolibrary.org/obo/GO_0002688 regulation of leukocyte chemotaxis Any process that modulates the rate, frequency or extent of mast cell chemotaxis. Mast cell chemotaxis is the movement of a mast cell in response to an external stimulus. http://purl.obolibrary.org/obo/UBERON_0003942 somatosensory system http://purl.obolibrary.org/obo/UBERON_0001032 sensory system The sensory system for the sense of touch and pain. http://purl.obolibrary.org/obo/GO_0060754 positive regulation of mast cell chemotaxis http://purl.obolibrary.org/obo/GO_0060753 regulation of mast cell chemotaxis Any process that increases the rate, frequency or extent of mast cell chemotaxis. Mast cell chemotaxis is the movement of a mast cell in response to an external stimulus. http://purl.obolibrary.org/obo/UBERON_0003946 placenta labyrinth http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure The placental layers where embryonic blood vessels are surrounded by trophoblast cells and maternal blood. http://purl.obolibrary.org/obo/GO_0060755 negative regulation of mast cell chemotaxis http://purl.obolibrary.org/obo/GO_0060753 regulation of mast cell chemotaxis Any process that decreases the rate, frequency or extent of mast cell chemotaxis. Mast cell chemotaxis is the movement of a mast cell in response to an external stimulus. http://purl.obolibrary.org/obo/UBERON_0003947 brain ventricle/choroid plexus http://purl.obolibrary.org/obo/UBERON_0010000 multicellular anatomical structure The brain ventricles or their associated choroid plexuses. http://purl.obolibrary.org/obo/GO_0060762 regulation of branching involved in mammary gland duct morphogenesis http://purl.obolibrary.org/obo/GO_0060688 regulation of morphogenesis of a branching structure Any process that modulates the rate, frequency, or extent of branching involved in mammary gland duct morphogenesis. http://purl.obolibrary.org/obo/UBERON_0003952 anterior stroma of cornea http://purl.obolibrary.org/obo/UBERON_0003566 head connective tissue The anterior segment of the lamellated connective tissue layer of the cornea. http://purl.obolibrary.org/obo/GO_0060764 cell-cell signaling involved in mammary gland development http://purl.obolibrary.org/obo/GO_0007267 cell-cell signaling Any process that mediates the transfer of information from one cell to another and contributes to the progression of the mammary gland, from its initial state to the mature structure. http://purl.obolibrary.org/obo/UBERON_0003953 posterior stroma of cornea http://purl.obolibrary.org/obo/UBERON_0003566 head connective tissue The posterior segment of the lamellated connective tissue layer of the cornea. http://purl.obolibrary.org/obo/UBERON_0003956 aqueous drainage system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system The structures associated with drainage of the aqueous humor from the eye, that include the trabecular meshwork, Schlemm's canal, the uveoscleral network, and the aqueous veins. http://purl.obolibrary.org/obo/GO_0060767 epithelial cell proliferation involved in prostate gland development http://purl.obolibrary.org/obo/GO_0050673 epithelial cell proliferation The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population that contributes to the progression of the prostate gland over time. http://purl.obolibrary.org/obo/UBERON_0003962 pterygopalatine ganglion http://purl.obolibrary.org/obo/UBERON_0001808 parasympathetic ganglion The small parasympathetic ganglion that supplies nerve fibers to the lacrimal, nasal, palatine and pharyngeal glands. http://purl.obolibrary.org/obo/GO_0060768 regulation of epithelial cell proliferation involved in prostate gland development http://purl.obolibrary.org/obo/GO_0050678 regulation of epithelial cell proliferation Any process that modulates the rate, frequency or extent of epithelial cell proliferation that contributes to the progression of the prostate gland over time. http://purl.obolibrary.org/obo/UBERON_0003963 otic ganglion http://purl.obolibrary.org/obo/UBERON_0001808 parasympathetic ganglion The ganglion that supplies nerve fibers to the parotid gland. http://purl.obolibrary.org/obo/GO_0060769 positive regulation of epithelial cell proliferation involved in prostate gland development http://purl.obolibrary.org/obo/GO_0060768 regulation of epithelial cell proliferation involved in prostate gland development Any process that increases the rate, frequency or extent of epithelial cell proliferation that contributes to the progression of the prostate gland over time. http://purl.obolibrary.org/obo/UBERON_0003964 prevertebral ganglion http://purl.obolibrary.org/obo/UBERON_0001806 sympathetic ganglion The sympathetic ganglia located in front of the vertebral column and are associated with the major branches of the abdominal aorta; these include the celiac, aorticorenal, superior and inferior mesenteric ganglia. http://purl.obolibrary.org/obo/GO_0060770 negative regulation of epithelial cell proliferation involved in prostate gland development http://purl.obolibrary.org/obo/GO_0060768 regulation of epithelial cell proliferation involved in prostate gland development Any process that decreases the rate, frequency or extent of epithelial cell proliferation that contributes to the progression of the prostate gland over time. http://purl.obolibrary.org/obo/UBERON_0003967 cutaneous elastic tissue http://purl.obolibrary.org/obo/UBERON_0002521 elastic tissue The slender connective tissue fiber in the extracellular matrix of skin tissue that is composed of microfibrils and amorphous elastin and is characterized by great elasticity. http://purl.obolibrary.org/obo/GO_0060784 regulation of cell proliferation involved in tissue homeostasis http://purl.obolibrary.org/obo/GO_0042127 regulation of cell population proliferation Any process that modulates the frequency, rate or extent of cell proliferation resulting in the maintenance of a steady-state number of cells within a tissue. http://purl.obolibrary.org/obo/UBERON_0003970 placental labyrinth vasculature http://purl.obolibrary.org/obo/UBERON_0006876 vasculature of organ Blood vessels of the layer of the placenta where embryonic and maternal blood vessels interdigitate. http://purl.obolibrary.org/obo/UBERON_0003975 internal female genitalia http://purl.obolibrary.org/obo/UBERON_0004175 internal genitalia The internal feminine genital organs, including the ovaries, uterine tubes, uterus, uterine cervix, and vagina. http://purl.obolibrary.org/obo/GO_0060785 regulation of apoptosis involved in tissue homeostasis http://purl.obolibrary.org/obo/GO_0042981 regulation of apoptotic process Any process that modulates the occurrence or rate of cell death by apoptosis that results in the maintenance of the steady-state number of cells within a tissue. http://purl.obolibrary.org/obo/UBERON_0003980 cerebellum fissure http://purl.obolibrary.org/obo/UBERON_0014466 subarachnoid fissure One of a set of deep furrows which divide the lobules of the cerebellum. Examples: postcentral, primary and secondary furrows. http://purl.obolibrary.org/obo/GO_0060786 regulation of cell differentiation involved in tissue homeostasis http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the frequency, rate or extent of cell differentiation that contributes to the maintenance of a steady state of a cell type within a tissue. http://purl.obolibrary.org/obo/UBERON_0003981 primordial ovarian follicle http://purl.obolibrary.org/obo/UBERON_0001305 ovarian follicle Primordial follicles are indiscernible to the naked eye and develop to primary, secondary, and finally mature vesicular follicles. http://purl.obolibrary.org/obo/GO_0060789 hair follicle placode formation http://purl.obolibrary.org/obo/GO_0060788 ectodermal placode formation The developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud. http://purl.obolibrary.org/obo/UBERON_0003984 uterine tube infundibulum http://purl.obolibrary.org/obo/UBERON_0013515 subdivision of oviduct The funnel-like expansion of the abdominal extremity of the uterine tube[MP]. http://purl.obolibrary.org/obo/GO_0060790 tooth placode formation http://purl.obolibrary.org/obo/GO_0060788 ectodermal placode formation The developmental process in which the tooth placode forms. A tooth placode is a thickening of the ectoderm that will give rise to the tooth bud. http://purl.obolibrary.org/obo/UBERON_0003988 thymus corticomedullary boundary http://purl.obolibrary.org/obo/UBERON_0007651 anatomical junction The dense region demarcating the thymus medulla from the surrounding cortex that is characterized by numerous blood vessels (predominantly arterioles) with some perivascular connective tissue, mature and immature T lymphocytes, dendritic cells, variable numbers of perivascular B-lymphocytes and plasma cells; site of entry of bone marrow stem cells and exit of mature, functional T cells. http://purl.obolibrary.org/obo/GO_0060791 sebaceous gland placode formation http://purl.obolibrary.org/obo/GO_0060788 ectodermal placode formation The developmental process in which a sebaceous gland placode forms. A sebaceous gland placode is a thickening of the ectoderm that will give rise to the sebaceous gland bud. http://purl.obolibrary.org/obo/UBERON_0003990 spinal cord motor column http://purl.obolibrary.org/obo/UBERON_0016550 spinal cord column The subclasses of motor neurons which are organized into longitudinally oriented columns that occupy distinct and, in some cases, discontinuous domains along the rostrocaudal axis of the spinal cord; motor neurons within a single column send their axons to a common peripheral target. http://purl.obolibrary.org/obo/GO_0060792 sweat gland development http://purl.obolibrary.org/obo/GO_0048732 gland development The progression of the sweat gland over time, from its formation to the mature structure. Sweat glands secrete an aqueous solution that is used in thermoregulation. http://purl.obolibrary.org/obo/UBERON_0004001 olfactory bulb layer http://purl.obolibrary.org/obo/UBERON_0022303 nervous system cell part layer Missing definition for term UBERON:0004001. Please replace it using linked reference. http://purl.obolibrary.org/obo/GO_0060793 sweat gland placode formation http://purl.obolibrary.org/obo/GO_0060788 ectodermal placode formation The developmental process in which the sweat gland placode forms. An sweat gland placode is a thickening of the ectoderm that will give rise to the sweat gland bud. http://purl.obolibrary.org/obo/UBERON_0004003 cerebellum hemisphere lobule http://purl.obolibrary.org/obo/UBERON_0004004 cerebellum lobule The region of a cerebellar lobule that resides in either of the lateral sections of the cerebellum outside the vermis; in mammals, the vermis portion of the cerebellum has a foliation pattern along the AP axis that is distinct from the lateral cerebellar hemispheres. http://purl.obolibrary.org/obo/GO_0060800 regulation of cell differentiation involved in embryonic placenta development http://purl.obolibrary.org/obo/GO_2000241 regulation of reproductive process Any process that modulates the rate, frequency or extent of cell differentiation that contributes to the progression of the placenta over time, from its initial condition to its mature state. http://purl.obolibrary.org/obo/UBERON_0004004 cerebellum lobule http://purl.obolibrary.org/obo/UBERON_0002749 regional part of cerebellar cortex One of the the ten gyri of the cerebellar cortex. http://purl.obolibrary.org/obo/GO_0060806 negative regulation of cell differentiation involved in embryonic placenta development http://purl.obolibrary.org/obo/GO_0060800 regulation of cell differentiation involved in embryonic placenta development Any process that decreases the rate, frequency or extent of cell differentiation that contributes to the progression of the placenta over time, from its initial condition to its mature state. http://purl.obolibrary.org/obo/UBERON_0004008 cerebellar plate http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue The embryonic pseudostratified epithelium of the fourth cerebellar ventricle that eventually forms the vermis and ventral neuroepithelium. http://purl.obolibrary.org/obo/GO_0060836 lymphatic endothelial cell differentiation http://purl.obolibrary.org/obo/GO_0045446 endothelial cell differentiation The process in which a venous blood vessel endothelial cell acquires specialized features of a lymphatic vessel endothelial cell, a thin flattened cell that lines the inside surfaces of lymph vessels. http://purl.obolibrary.org/obo/UBERON_0004015 embryonic-extraembryonic boundary http://purl.obolibrary.org/obo/UBERON_0000015 non-material anatomical boundary The connection between the embryo proper and extraembryonic tissues. http://purl.obolibrary.org/obo/GO_0060837 blood vessel endothelial cell differentiation http://purl.obolibrary.org/obo/GO_0045446 endothelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a blood vessel endothelial cell, a thin flattened cell that lines the inside surfaces of blood vessels. http://purl.obolibrary.org/obo/UBERON_0004016 dermatome http://purl.obolibrary.org/obo/UBERON_0017650 developing mesenchymal structure A transitional population of migrating mesenchymal cells that derive from somites and that will become dermal cells. http://purl.obolibrary.org/obo/GO_0060842 arterial endothelial cell differentiation http://purl.obolibrary.org/obo/GO_0060837 blood vessel endothelial cell differentiation The process in which a relatively unspecialized endothelial cell acquires specialized features of an arterial endothelial cell, a thin flattened cell that lines the inside surfaces of arteries. http://purl.obolibrary.org/obo/UBERON_0004021 spongiotrophoblast layer http://purl.obolibrary.org/obo/UBERON_0005292 extraembryonic tissue The structure of the outer structural layer of the rodent placenta[MP]. http://purl.obolibrary.org/obo/GO_0060843 venous endothelial cell differentiation http://purl.obolibrary.org/obo/GO_0060837 blood vessel endothelial cell differentiation The process in which a relatively unspecialized endothelial cell acquires specialized features of a venous endothelial cell, a thin flattened cell that lines the inside surfaces of veins. http://purl.obolibrary.org/obo/UBERON_0004022 germinal neuroepithelium http://purl.obolibrary.org/obo/UBERON_0034706 proliferating neuroepithelium The single layer of epithelial cells that lines the early neural tube and develops into the nervous system and into the neural crest cells. http://purl.obolibrary.org/obo/GO_0060854 branching involved in lymph vessel morphogenesis http://purl.obolibrary.org/obo/GO_0048754 branching morphogenesis of an epithelial tube The process of the coordinated growth and sprouting of lymph vessels giving rise to the organized lymphatic system. http://purl.obolibrary.org/obo/UBERON_0004023 ganglionic eminence http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure The transient proliferative population of neurons that expands exponentially during late prenatal development; it is a continuous germinal zone distinct from the ventricular zone that surrounds the brain ventricles[MP]. http://purl.obolibrary.org/obo/GO_0060876 semicircular canal formation http://purl.obolibrary.org/obo/GO_0035148 tube formation The developmental process pertaining to the initial formation of the semicircular canal from the otic vesicle. This process begins with the regionalization of the vesicle that specifies the area where the vesicles will form and continues through the process of fusion which forms the initial tubes. http://purl.obolibrary.org/obo/UBERON_0004024 medial ganglionic eminence http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure A distinct elevation of a transient proliferating cell mass of the fetal subventricular zone; this mass contributes most of its cells to the neocortex; however, hippocampal neurons, thalamus, septum and olfactory bulb neurons are also partly derived from the MGE. http://purl.obolibrary.org/obo/GO_0060887 limb epidermis development http://purl.obolibrary.org/obo/GO_0098773 skin epidermis development The process whose specific outcome is the progression of the epidermis of the limb over time, from its formation to the mature structure. The limb epidermis is the outer epithelial layer of the limb, it is a complex stratified squamous epithelium. http://purl.obolibrary.org/obo/UBERON_0004025 lateral ganglionic eminence http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure A distinct elevation of a transient proliferating cell mass of the fetal subventricular zone; this mass contributes most of its cells to the striatum; however, neocortex, thalamus, septum and olfactory bulb neurons are also partly derived from the LGE. http://purl.obolibrary.org/obo/GO_0060907 positive regulation of macrophage cytokine production http://purl.obolibrary.org/obo/GO_0010935 regulation of macrophage cytokine production Any process that increases the rate, frequency or extent of macrophage cytokine production. Macrophage cytokine production is the appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. http://purl.obolibrary.org/obo/UBERON_0004026 caudal ganglionic eminence http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure The caudally located, distinct elevation of a transient proliferating cell mass of the fetal subventricular zone, located adjacent to the lateral ventricle. http://purl.obolibrary.org/obo/GO_0060915 mesenchymal cell differentiation involved in lung development http://purl.obolibrary.org/obo/GO_0048762 mesenchymal cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell of the lung. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types. http://purl.obolibrary.org/obo/UBERON_0004027 chorionic plate http://purl.obolibrary.org/obo/UBERON_0005292 extraembryonic tissue That portion of the chorionic wall in the region of its uterine attachment, which gives rise to chorionic villi; it consists of the mesoderm that lines the chorionic vesicle and, on the maternal side, of the trophoblast that lines the intervillous spaces; in the last half of gestation, the mesodermal connective tissue is largely replaced by fibrinoid material, and the amnionic membrane is adherent to the fetal side of the plate. http://purl.obolibrary.org/obo/GO_0060916 mesenchymal cell proliferation involved in lung development http://purl.obolibrary.org/obo/GO_0010463 mesenchymal cell proliferation The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population that contributes to the progression of the lung over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets. http://purl.obolibrary.org/obo/UBERON_0004029 canal of Schlemm http://purl.obolibrary.org/obo/UBERON_0009141 craniocervical region vein The vascular structure encircling the anterior chamber of the eye, through which the aqueous humor is returned to the blood circulation. http://purl.obolibrary.org/obo/GO_0060920 cardiac pacemaker cell differentiation http://purl.obolibrary.org/obo/GO_0055007 cardiac muscle cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a pacemaker cell. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions. http://purl.obolibrary.org/obo/UBERON_0004035 cortical subplate http://purl.obolibrary.org/obo/UBERON_0014950 layer of developing cerebral cortex The transient outer neural tube region that contains the first generated post-mitotic neurons that receive synaptic input from thalamic axons and in turn project axons to the developing cortical plate. http://purl.obolibrary.org/obo/GO_0060921 sinoatrial node cell differentiation http://purl.obolibrary.org/obo/GO_0060920 cardiac pacemaker cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a sinoatrial (SA) node cell. SA node cells are pacemaker cells that are found in the sinoatrial node. http://purl.obolibrary.org/obo/UBERON_0004040 cortical intermediate zone http://purl.obolibrary.org/obo/UBERON_0014950 layer of developing cerebral cortex The region of the developing mammalian cortex that extends between the ventricular zone and the cortical plate (CP); normally, the IZ is a region of tangential migration of cells, and at midgestation, the lower part of the IZ develops into the subventricular zone. http://purl.obolibrary.org/obo/GO_0060922 atrioventricular node cell differentiation http://purl.obolibrary.org/obo/GO_0060920 cardiac pacemaker cell differentiation The process in which a relatively unspecialized cell acquires specialized features of an atrioventricular (AV) node cell. AV node cells are pacemaker cells that are found in the atrioventricular node. http://purl.obolibrary.org/obo/UBERON_0004041 spleen primary B follicle http://purl.obolibrary.org/obo/UBERON_0010422 primary nodular lymphoid tissue The nodules of small undifferentiated B lymphocytes and follicular dendritic cells located in the spleen white pulp. http://purl.obolibrary.org/obo/GO_0060926 cardiac pacemaker cell development http://purl.obolibrary.org/obo/GO_0055013 cardiac muscle cell development The process whose specific outcome is the progression of a pacemaker cell over time, from its formation to the mature state. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions. http://purl.obolibrary.org/obo/UBERON_0004042 spleen secondary B follicle http://purl.obolibrary.org/obo/UBERON_0001745 secondary nodular lymphoid tissue The nodules of antigen-activated, differentiating B cells, follicular dendritic cells, antigen-presenting T cells and macrophages in the spleen white pulp. http://purl.obolibrary.org/obo/GO_0060928 atrioventricular node cell development http://purl.obolibrary.org/obo/GO_0060926 cardiac pacemaker cell development The process whose specific outcome is the progression of an atrioventricular (AV) node cell over time, from its formation to the mature state. http://purl.obolibrary.org/obo/UBERON_0004043 semicircular canal ampulla http://purl.obolibrary.org/obo/UBERON_0010000 multicellular anatomical structure The spherical enlargement at the base of each semicircular canal where they connect with the utricle, containing the crista ampullaris which detects movement of the fluid within the canals. http://purl.obolibrary.org/obo/GO_0060931 sinoatrial node cell development http://purl.obolibrary.org/obo/GO_0060926 cardiac pacemaker cell development The process whose specific outcome is the progression of a sinoatrial (SA) node cell over time, from its formation to the mature state. SA node cells are pacemaker cells that are found in the sinoatrial node. http://purl.obolibrary.org/obo/UBERON_0004044 anterior visceral endoderm http://purl.obolibrary.org/obo/UBERON_0004877 visceral endoderm The extraembryonic tissue that is responsible for the proper orientation of the anterior-posterior axis of the embryo and for appropriate patterning of adjacent embryonic tissue. http://purl.obolibrary.org/obo/GO_0060933 His-Purkinje system cell development http://purl.obolibrary.org/obo/GO_0055006 cardiac cell development The process whose specific outcome is the progression of a His-Purkinje cell over time, from its formation to the mature state. These cells form the fibers that regulate cardiac muscle contraction in the ventricles. http://purl.obolibrary.org/obo/UBERON_0004053 external male genitalia http://purl.obolibrary.org/obo/UBERON_0004176 external genitalia The external masculine genital organs. http://purl.obolibrary.org/obo/GO_0060935 cardiac fibroblast cell differentiation http://purl.obolibrary.org/obo/GO_0035051 cardiocyte differentiation The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules. http://purl.obolibrary.org/obo/UBERON_0004054 internal male genitalia http://purl.obolibrary.org/obo/UBERON_0004175 internal genitalia The internal masculine genital organs, including the testes, epididymides, deferent ducts, seminal vesicles, prostate, ejaculatory ducts, and bulbourethral glands. http://purl.obolibrary.org/obo/GO_0060936 cardiac fibroblast cell development http://purl.obolibrary.org/obo/GO_0055006 cardiac cell development The process whose specific outcome is the progression of a cardiac fibroblast over time, from its formation to the mature state. A cardiac fibroblast is a connective tissue cell of the heart which secretes an extracellular matrix rich in collagen and other macromolecules. http://purl.obolibrary.org/obo/UBERON_0004058 biliary ductule http://purl.obolibrary.org/obo/UBERON_0000025 tube One of the fine terminal elements of the bile duct system, leaving the portal canal, and pursuing a course at the periphery of a lobule of the liver[BTO]. the excretory ducts of the liver that connect the interlobular ductules to the right or left hepatic duct[MP]. http://purl.obolibrary.org/obo/GO_0060945 cardiac neuron differentiation http://purl.obolibrary.org/obo/GO_0035051 cardiocyte differentiation The process in which a relatively unspecialized cell acquires specialized features of a neuron of the heart. http://purl.obolibrary.org/obo/UBERON_0004059 spinal cord medial motor column http://purl.obolibrary.org/obo/UBERON_0003990 spinal cord motor column The subclasses of motor neurons which project their axons to axial muscles that lie close to the vertebral column; motor neurons in the lateral subdivision of the MMC project their axons to body wall muscles. http://purl.obolibrary.org/obo/GO_0060946 cardiac blood vessel endothelial cell differentiation http://purl.obolibrary.org/obo/GO_0060837 blood vessel endothelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a blood vessel endothelial cell of the heart. Blood vessel endothelial cells are thin flattened cells that line the inside surfaces of blood vessels. http://purl.obolibrary.org/obo/UBERON_0004060 neural tube ventricular layer http://purl.obolibrary.org/obo/UBERON_0034706 proliferating neuroepithelium The layer of undifferentiated, proliferating cells that line the neural tube lumen that is the immediate transformation of the germinal neuroepithelium. http://purl.obolibrary.org/obo/GO_0060950 cardiac glial cell differentiation http://purl.obolibrary.org/obo/GO_0035051 cardiocyte differentiation The process in which a relatively unspecialized cell acquires the specialized features of a glial cell of the heart. http://purl.obolibrary.org/obo/UBERON_0004061 neural tube mantle layer http://purl.obolibrary.org/obo/UBERON_0034707 differentiating neuroepithelium The layer of glia and differentiating neurons that forms as a second layer around the germinal neuroepithium; as this develops it comes to lie between the ventricular and marginal layers and includes the basal and alar plates. Develops into neurons and glia forming a gray matter layer. http://purl.obolibrary.org/obo/GO_0060952 cardiac glial cell development http://purl.obolibrary.org/obo/GO_0055006 cardiac cell development The process aimed at the progression of a cardiac glial cell over time, from its formation to the fully functional mature cell. http://purl.obolibrary.org/obo/UBERON_0004062 neural tube marginal layer http://purl.obolibrary.org/obo/UBERON_0005162 multi cell part structure The outermost layer of the neural tube that consists of axons from the developing mantle layer and will form the white matter. http://purl.obolibrary.org/obo/GO_0060956 endocardial cell differentiation http://purl.obolibrary.org/obo/GO_0003348 cardiac endothelial cell differentiation The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an endocardial cell. An endocardial cell is a specialized endothelial cell that makes up the endocardium portion of the heart. The endocardium is the innermost layer of tissue of the heart, and lines the heart chambers. http://purl.obolibrary.org/obo/UBERON_0004063 spinal cord alar plate http://purl.obolibrary.org/obo/UBERON_0005882 neural tube alar plate The region of the mantle layer of the neural tube that lies dorsal to the sulcus limitans and contains primarily sensory neurons and interneurons involved in communication of sensory impulses; the alar plate develops into the dorsal horn in the grey matter of the spinal cord. http://purl.obolibrary.org/obo/GO_0060958 endocardial cell development http://purl.obolibrary.org/obo/GO_0055006 cardiac cell development The progression of an endocardial cell over time, from its formation to the mature cell. An endocardial cell is a specialized endothelial cell that makes up the endocardium portion of the heart. http://purl.obolibrary.org/obo/UBERON_0004064 neural tube basal plate http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue The region of the mantle layer of the neural tube that lies ventral to the sulcus limitans and contains primarily motor neurons and interneurons. http://purl.obolibrary.org/obo/GO_0060959 cardiac neuron development http://purl.obolibrary.org/obo/GO_0055006 cardiac cell development The process whose specific outcome is the progression of a cardiac neuron over time, from its formation to the mature state. http://purl.obolibrary.org/obo/UBERON_0004066 frontonasal prominence http://purl.obolibrary.org/obo/UBERON_0009292 embryonic nasal process The unpaired embryonic prominence that is formed by the tissues surrounding the forebrain vesicle and develops into the forehead and bridge of the nose/snout. http://purl.obolibrary.org/obo/GO_0060978 angiogenesis involved in coronary vascular morphogenesis http://purl.obolibrary.org/obo/GO_0001525 angiogenesis Blood vessel formation in the heart when new vessels emerge from the proliferation of pre-existing blood vessels. http://purl.obolibrary.org/obo/UBERON_0004067 lateral nasal prominence http://purl.obolibrary.org/obo/UBERON_0009292 embryonic nasal process The lateral area of the two branches of a horseshoe-shaped mesenchymal swelling in the future nasal region of the embryo; it separates the olfactory pit from the developing eye and the ala of the nose/snout develops from it. http://purl.obolibrary.org/obo/GO_0060979 vasculogenesis involved in coronary vascular morphogenesis http://purl.obolibrary.org/obo/GO_0001570 vasculogenesis The differentiation of endothelial cells from progenitor cells that contributes to blood vessel development in the heart, and the de novo formation of blood vessels and tubes. http://purl.obolibrary.org/obo/UBERON_0004068 medial nasal prominence http://purl.obolibrary.org/obo/UBERON_0009292 embryonic nasal process The central area of the two limbs of a horseshoe-shaped mesenchymal swelling that lie medial to the olfactory placode or pit in the future nasal region of the embryo; it joins with the ipsilateral maxillary prominence in the formation of half of the upper jaw, and the nasal tip and philtrum of the upper lip develop from it. http://purl.obolibrary.org/obo/GO_0060980 cell migration involved in coronary vasculogenesis http://purl.obolibrary.org/obo/GO_0035441 cell migration involved in vasculogenesis The orderly movement of a cell from one site to another that will contribute to the differentiation of an endothelial cell that will form the blood vessels of the heart. http://purl.obolibrary.org/obo/UBERON_0004070 cerebellum vermis lobule http://purl.obolibrary.org/obo/UBERON_0004004 cerebellum lobule The region of a cerebellar lobule that resides in the central section of the cerebellum between the two hemispheres. http://purl.obolibrary.org/obo/UBERON_0004073 cerebellum interpositus nucleus http://purl.obolibrary.org/obo/UBERON_0008995 nucleus of cerebellar nuclear complex The nucleus composed of the globose and emoliform nuclei of the cerebellum; in some mammalian species the globose nucleus is not distinguishable. http://purl.obolibrary.org/obo/GO_0060981 cell migration involved in coronary angiogenesis http://purl.obolibrary.org/obo/GO_0060973 cell migration involved in heart development The orderly movement of a cell from one site to another that will contribute to the formation of new blood vessels in the heart from pre-existing blood vessels. http://purl.obolibrary.org/obo/UBERON_0004083 cerebellum vermis lobule X http://purl.obolibrary.org/obo/UBERON_0004070 cerebellum vermis lobule Missing definition for term UBERON:0004083. Please replace it using linked reference. http://purl.obolibrary.org/obo/GO_0060982 coronary artery morphogenesis http://purl.obolibrary.org/obo/GO_0048844 artery morphogenesis The process in which the anatomical structures of coronary arteries are generated and organized. Coronary arteries are blood vessels that transport blood to the heart muscle. http://purl.obolibrary.org/obo/UBERON_0004087 vena cava http://purl.obolibrary.org/obo/UBERON_0013768 great vessel of heart Any of the veins that carries deoxygenated blood from a part of the body into the right atrium of the heart. http://purl.obolibrary.org/obo/GO_0061006 regulation of cell proliferation involved in kidney morphogenesis http://purl.obolibrary.org/obo/GO_0042127 regulation of cell population proliferation Any process that modulates the frequency, rate or extent of cell proliferation that contributes to the shaping of the kidney. http://purl.obolibrary.org/obo/UBERON_0004088 orbital region http://purl.obolibrary.org/obo/UBERON_0001444 subdivision of head The subdivision of the face that includes the eye (eyeball plus adnexa such as eyelids) and the orbit of the skull and associated parts of the face such as the eyebrows, if present. http://purl.obolibrary.org/obo/GO_0061007 hepaticobiliary system process http://purl.obolibrary.org/obo/GO_0003008 system process A system process carried out by any of the organs or tissues of the hepaticobiliary system. The hepaticobiliary system is responsible for metabolic and catabolic processing of small molecules absorbed from the blood or gut, hormones and serum proteins, detoxification, storage of glycogen, triglycerides, metals and lipid soluble vitamins and excretion of bile. Included are the synthesis of albumin, blood coagulation factors, complement, and specific binding proteins. http://purl.obolibrary.org/obo/UBERON_0004089 midface http://purl.obolibrary.org/obo/UBERON_0001444 subdivision of head The middle of the face including the nose and its associated bony structures[MW]. http://purl.obolibrary.org/obo/GO_0061010 gallbladder development http://purl.obolibrary.org/obo/GO_0048513 animal organ development The progression of the gallbladder over time, from its initial formation to the mature structure. The gallbladder is a cavitated organ that stores bile. http://purl.obolibrary.org/obo/UBERON_0004099 joint space of elbow http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space Joint cavity shared by all the joints of the elbow. The elbow joint is a compound joint that actually comprises three separate joints: the joints connecting the upper and lower arm: 1) Articulatio humero-ulnaris and 2) Articulatio humero-radialis as well as the proximal joint connecting the forarm bones: 3) Articulatio radio-ulnaris proximalis. All three share a joint cavity which is highly sinuated/scalloped/coved. Joint spaces of the elbow summarizes the joint cavity shared by all three adjoining joints of the elbow joint. http://purl.obolibrary.org/obo/GO_0061011 hepatic duct development http://purl.obolibrary.org/obo/GO_0061009 common bile duct development The progression of the hepatic duct over time, from its formation to the mature structure. The hepatic duct is the duct that leads from the liver to the common bile duct. http://purl.obolibrary.org/obo/UBERON_0004100 renal collecting system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system The collecting duct system of the kidney consists of a series of tubules and ducts that connect the nephrons to the ureter. It participates in electrolyte and fluid balance through reabsorption and excretion, processes regulated by the hormones aldosterone and antidiuretic hormone. http://purl.obolibrary.org/obo/GO_0061017 hepatoblast differentiation http://purl.obolibrary.org/obo/GO_0048863 stem cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a hepatoblast. A hepatoblast is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into hepatocytes and cholangiocytes. http://purl.obolibrary.org/obo/UBERON_0004103 alveolar ridge http://purl.obolibrary.org/obo/UBERON_0005913 zone of bone organ One of the two jaw ridges either on the roof of the mouth between the upper teeth and the hard palate or on the bottom of the mouth behind the lower teeth[WP]. The alveolar ridges contain the sockets (alveoli) of the teeth[HP]. http://purl.obolibrary.org/obo/GO_0061029 eyelid development in camera-type eye http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the eyelid in a camera-type eye from its formation to the mature state. The eyelid is a membranous cover that helps protect and lubricate the eye. http://purl.obolibrary.org/obo/UBERON_0004105 subungual region http://purl.obolibrary.org/obo/UBERON_0000477 anatomical cluster Region beneath a nail or claw. http://purl.obolibrary.org/obo/GO_0061030 epithelial cell differentiation involved in mammary gland alveolus development http://purl.obolibrary.org/obo/GO_0060644 mammary gland epithelial cell differentiation The process in which a relatively unspecialized epithelial cell becomes a more specialized epithelial cell of the mammary gland alveolus. http://purl.obolibrary.org/obo/UBERON_0004109 cortex of humerus http://purl.obolibrary.org/obo/UBERON_0005808 bone tissue of long bone The outer or sperficial part of the humerus. http://purl.obolibrary.org/obo/GO_0061032 visceral serous pericardium development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the visceral serous pericardium from its formation to the mature structure. The visceral serous pericardium is the inner layer of the pericardium. http://purl.obolibrary.org/obo/UBERON_0004111 anatomical conduit http://purl.obolibrary.org/obo/UBERON_0010000 multicellular anatomical structure Any tube, opening or passage that connects two distinct anatomical spaces. http://purl.obolibrary.org/obo/GO_0061034 olfactory bulb mitral cell layer development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the olfactory bulb mitral cell layer over time from its initial formation until its mature state. The mitral cell layer is composed of pyramidal neurons whose cell bodies are located between the granule cell layer and the plexiform layer. http://purl.obolibrary.org/obo/UBERON_0004113 muscle of auditory ossicle http://purl.obolibrary.org/obo/UBERON_0002376 cranial muscle A muscle of the tympanic cavity that attaches to an auditory ossicle. http://purl.obolibrary.org/obo/GO_0061038 uterus morphogenesis http://purl.obolibrary.org/obo/GO_0009887 animal organ morphogenesis The process in which anatomical structures of the uterus are generated and organized. http://purl.obolibrary.org/obo/UBERON_0004114 tympanic cavity http://purl.obolibrary.org/obo/UBERON_0010064 open anatomical space Small cavity surrounding the bones of the middle ear. http://purl.obolibrary.org/obo/GO_0061040 female gonad morphogenesis http://purl.obolibrary.org/obo/GO_0035262 gonad morphogenesis The process in which a female gonad is generated and organized. http://purl.obolibrary.org/obo/UBERON_0004115 blood vessel of tympanic cavity http://purl.obolibrary.org/obo/UBERON_0003496 head blood vessel A blood vessel that is part of a tympanic cavity [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0061046 regulation of branching involved in lung morphogenesis http://purl.obolibrary.org/obo/GO_0060688 regulation of morphogenesis of a branching structure Any process that modulates the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units. http://purl.obolibrary.org/obo/UBERON_0004116 nerve of tympanic cavity http://purl.obolibrary.org/obo/UBERON_0011779 nerve of head region A nerve that is part of a tympanic cavity [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0061047 positive regulation of branching involved in lung morphogenesis http://purl.obolibrary.org/obo/GO_0061046 regulation of branching involved in lung morphogenesis Any process that increases the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units. http://purl.obolibrary.org/obo/UBERON_0004118 vasculature of iris http://purl.obolibrary.org/obo/UBERON_0002203 vasculature of eye A vasculature that is part of a iris [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0061048 negative regulation of branching involved in lung morphogenesis http://purl.obolibrary.org/obo/GO_0061046 regulation of branching involved in lung morphogenesis Any process that decreases the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units. http://purl.obolibrary.org/obo/UBERON_0004119 endoderm-derived structure http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure An anatomical structure that develops (entirely or partially) from the endoderm. http://purl.obolibrary.org/obo/GO_0061050 regulation of cell growth involved in cardiac muscle cell development http://purl.obolibrary.org/obo/GO_0055021 regulation of cardiac muscle tissue growth Any process that modulates the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state. http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure An anatomical structure that develops (entirely or partially) from the mesoderm. http://purl.obolibrary.org/obo/GO_0061051 positive regulation of cell growth involved in cardiac muscle cell development http://purl.obolibrary.org/obo/GO_0061050 regulation of cell growth involved in cardiac muscle cell development Any process that increases the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state. http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure An anatomical structure that develops (entirely or partially) from the ectoderm. http://purl.obolibrary.org/obo/GO_0061052 negative regulation of cell growth involved in cardiac muscle cell development http://purl.obolibrary.org/obo/GO_0061050 regulation of cell growth involved in cardiac muscle cell development Any process that decreases the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state. http://purl.obolibrary.org/obo/UBERON_0004122 genitourinary system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system Anatomical system that has as its parts the organs concerned with the production and excretion of urine and those concerned with reproduction. http://purl.obolibrary.org/obo/GO_0061054 dermatome development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin. http://purl.obolibrary.org/obo/UBERON_0004123 myocardial layer http://purl.obolibrary.org/obo/UBERON_0005983 heart layer Any of the layers of the myocardium. Example: compact layer, trabecular layer. http://purl.obolibrary.org/obo/GO_0061055 myotome development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the myotome over time, from its formation to the mature structure. The myotome is the portion of the somite that will give rise to muscle. http://purl.obolibrary.org/obo/UBERON_0004124 myocardium trabecular layer http://purl.obolibrary.org/obo/UBERON_0004123 myocardial layer The layer of the myocardium composed of projections of contractile myocytes. The trabecular layer is bounded internally by the endocardium. In zebrafish, unlike the trabeculations of higher vertebrates, both atrial and ventricular trabeculae have more strut-like character, and are more uniform without apparent regional differences[ZFA]. http://purl.obolibrary.org/obo/GO_0061056 sclerotome development http://purl.obolibrary.org/obo/GO_0060485 mesenchyme development The progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra. http://purl.obolibrary.org/obo/UBERON_0004126 trabecular layer of ventricle http://purl.obolibrary.org/obo/UBERON_0004124 myocardium trabecular layer A myocardium trabecular layer that is part of a cardiac ventricle. http://purl.obolibrary.org/obo/GO_0061068 urethra development http://purl.obolibrary.org/obo/GO_0048513 animal organ development The progression of the urethra over time from its initial formation to the mature structure. The urethra is a renal system organ that carries urine from the bladder to outside the body. http://purl.obolibrary.org/obo/UBERON_0004128 optic vesicle http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure The optic vesicle is the evagination of neurectoderm that precedes formation of the optic cup[GO]. Portion of tissue that is comprised of neuroepitheium which has pinched off from the anterior neural keel and will form the optic cup[ZFA]. http://purl.obolibrary.org/obo/GO_0061069 male urethra development http://purl.obolibrary.org/obo/GO_0061068 urethra development The progression of the male urethra over time from its initial formation to the mature structure. The male urethra is a renal system organ that carries urine from the bladder through the penis to outside the body. http://purl.obolibrary.org/obo/UBERON_0004129 growth plate cartilage http://purl.obolibrary.org/obo/UBERON_0002418 cartilage tissue Cartilage that will provide a scaffold for mineralization of endochondral bones as they elongate or grow. http://purl.obolibrary.org/obo/GO_0061070 female urethra development http://purl.obolibrary.org/obo/GO_0061068 urethra development The progression of the female urethra over time from its initial formation to the mature structure. The female urethra is a renal system organ that carries urine from the bladder to outside the body, exiting above the vaginal opening. http://purl.obolibrary.org/obo/UBERON_0004130 cerebellar layer http://purl.obolibrary.org/obo/UBERON_0016548 central nervous system gray matter layer A cortical cell layer of the cerebellum. Examples: the granular (inner+outer) layer, molecular layer, Purkinje cell layer, and the ventricular layer of the embryo. http://purl.obolibrary.org/obo/GO_0061071 urethra epithelium development http://purl.obolibrary.org/obo/GO_0060429 epithelium development The progression of the urethra epithelium over time from its initial formation to the mature structure. The urethra is a renal system organ that carries urine from the bladder to outside the body. The epithelium is the tubular, planar layer of cells through which the urine passes. http://purl.obolibrary.org/obo/UBERON_0004133 salivatory nucleus http://purl.obolibrary.org/obo/UBERON_0009662 hindbrain nucleus Missing definition for term UBERON:0004133. Please replace it using linked reference. http://purl.obolibrary.org/obo/GO_0061072 iris morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the iris is generated and organized. The iris is an anatomical structure in the eye whose opening forms the pupil. The iris is responsible for controlling the diameter and size of the pupil and the amount of light reaching the retina. http://purl.obolibrary.org/obo/UBERON_0004134 proximal tubule http://purl.obolibrary.org/obo/UBERON_0006853 renal cortex tubule In mammals, the proximal tubule is a nephron tubule that connects Bowman's capsule to the loop of Henle. It has a brush border epithelial morphology[GO]. http://purl.obolibrary.org/obo/GO_0061073 ciliary body morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the ciliary body generated and organized. The ciliary body is the circumferential tissue inside the eye composed of the ciliary muscle and ciliary processes. http://purl.obolibrary.org/obo/UBERON_0004135 distal tubule http://purl.obolibrary.org/obo/UBERON_0007685 region of nephron tubule The distal tubule is a nephron tubule that consists of the distal convoluted tubule and distal straight tubule segments. http://purl.obolibrary.org/obo/GO_0061074 regulation of neural retina development http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells. http://purl.obolibrary.org/obo/UBERON_0004136 intermediate tubule http://purl.obolibrary.org/obo/UBERON_0007685 region of nephron tubule The intermediate tubule is a nephron tubule that lies between the proximal and distal tubules. http://purl.obolibrary.org/obo/GO_0061075 positive regulation of neural retina development http://purl.obolibrary.org/obo/GO_1902868 positive regulation of retina development in camera-type eye Any process that increases the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells. http://purl.obolibrary.org/obo/UBERON_0004139 cardiogenic plate http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure The first recognizable structure derived from the heart field. http://purl.obolibrary.org/obo/GO_0061076 negative regulation of neural retina development http://purl.obolibrary.org/obo/GO_1902867 negative regulation of retina development in camera-type eye Any process that decreases the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells. http://purl.obolibrary.org/obo/UBERON_0004140 primary heart field http://purl.obolibrary.org/obo/UBERON_0007688 anlage A specific region of the lateral mesoderm that will form the primary beating heart tube. In mammals the primary heart field gives rise to the left ventricle. http://purl.obolibrary.org/obo/GO_0061080 right horn of sinus venosus development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the right horn of the sinus venosus from its formation to the mature structure. http://purl.obolibrary.org/obo/UBERON_0004141 heart tube http://purl.obolibrary.org/obo/UBERON_0012275 meso-epithelium An epithelial tube that will give rise to the mature heart. http://purl.obolibrary.org/obo/GO_0061100 lung neuroendocrine cell differentiation http://purl.obolibrary.org/obo/GO_0061140 lung secretory cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a neuroendocrine cell of the lung epithelium. http://purl.obolibrary.org/obo/UBERON_0004142 outflow tract septum http://purl.obolibrary.org/obo/UBERON_0002099 cardiac septum The outflow tract septum is a partition in the outflow tract. http://purl.obolibrary.org/obo/GO_0061101 neuroendocrine cell differentiation http://purl.obolibrary.org/obo/GO_0060563 neuroepithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a neuroendocrine cell. A neuroendocrine cell is a cell that receives input form a neuron which controls the secretion of an endocrine substance. http://purl.obolibrary.org/obo/UBERON_0004145 outflow tract http://purl.obolibrary.org/obo/UBERON_0004111 anatomical conduit The outflow tract is the portion of the heart through which blood flows into the arteries. http://purl.obolibrary.org/obo/GO_0061102 stomach neuroendocrine cell differentiation http://purl.obolibrary.org/obo/GO_0061101 neuroendocrine cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a neuroendocrine cell of the stomach epithelium. http://purl.obolibrary.org/obo/UBERON_0004146 His-Purkinje system http://purl.obolibrary.org/obo/UBERON_0018649 cardiac muscle tissue of ventricle The His-Purkinje system receives signals from the AV node and is composed of the fibers that regulate cardiac muscle contraction in the ventricles. http://purl.obolibrary.org/obo/GO_0061104 adrenal chromaffin cell differentiation http://purl.obolibrary.org/obo/GO_0061101 neuroendocrine cell differentiation The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of an adrenal chromaffin cell. An adrenal chromaffin cell is a neuroendocrine cell that stores epinephrine secretory vesicles. http://purl.obolibrary.org/obo/UBERON_0004148 cardiac vein http://purl.obolibrary.org/obo/UBERON_0013140 systemic vein Vein of heart that drains the myocardium. http://purl.obolibrary.org/obo/GO_0061105 regulation of stomach neuroendocrine cell differentiation http://purl.obolibrary.org/obo/GO_0045664 regulation of neuron differentiation Any process that modulates the rate, frequency or extent of the differentiation of a neuroendocrine cell in the stomach. http://purl.obolibrary.org/obo/UBERON_0004151 cardiac chamber http://purl.obolibrary.org/obo/UBERON_0000064 organ part A cardiac chamber surrounds an enclosed cavity within the heart. http://purl.obolibrary.org/obo/GO_0061106 negative regulation of stomach neuroendocrine cell differentiation http://purl.obolibrary.org/obo/GO_0061105 regulation of stomach neuroendocrine cell differentiation Any process that decreases the rate, frequency or extent of the differentiation of a neuroendocrine cell in the stomach. http://purl.obolibrary.org/obo/UBERON_0004160 proepicardium http://purl.obolibrary.org/obo/UBERON_0003104 mesenchyme An embryonic group of progenitor cells that forms from an outpouching of the septum transversum near the venous pole of the heart and gives rise to the epicardium. http://purl.obolibrary.org/obo/GO_0061107 seminal vesicle development http://purl.obolibrary.org/obo/GO_0048732 gland development The progression of the seminal vesicle over time, from its formation to the mature structure. The seminal vesicle is a gland that contributes to the production of semen. http://purl.obolibrary.org/obo/UBERON_0004161 septum transversum http://purl.obolibrary.org/obo/UBERON_0003104 mesenchyme A thick plate of mesodermal tissue that occupies the space between the thoracic cavity and yolk stalk in the early embryo, forming a transverse partition partially separating the coelomic cavity into thoracic and abdominal portions. It gives rise to the central tendon of the diaphragm[VHOG]. http://purl.obolibrary.org/obo/GO_0061108 seminal vesicle epithelium development http://purl.obolibrary.org/obo/GO_0060429 epithelium development The progression of the seminal vesicle epithelium over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/UBERON_0004164 branchiomeric muscle http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure A jaw muscle that arises from cranial mesenchyme and is innervated by cranial nerves. http://purl.obolibrary.org/obo/GO_0061109 dense core granule organization http://purl.obolibrary.org/obo/GO_0033363 secretory granule organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a dense core granule. A dense core granule is a secretory organelle found in endocrine cells. http://purl.obolibrary.org/obo/GO_0061113 pancreas morphogenesis http://purl.obolibrary.org/obo/GO_0009887 animal organ morphogenesis Morphogenesis of the pancreas. Morphogenesis is the process in which anatomical structures are generated and organized. http://purl.obolibrary.org/obo/UBERON_0004175 internal genitalia http://purl.obolibrary.org/obo/UBERON_0003133 reproductive organ The internal genitalia are the internal sex organs such as the uterine tube, the uterus and the vagina in female mammals, and the testis, seminal vesicle, ejaculatory duct and prostate in male mammals. http://purl.obolibrary.org/obo/GO_0061114 branching involved in pancreas morphogenesis http://purl.obolibrary.org/obo/GO_0061138 morphogenesis of a branching epithelium The process in which the branches of the pancreas are generated and organized. http://purl.obolibrary.org/obo/UBERON_0004176 external genitalia http://purl.obolibrary.org/obo/UBERON_0003133 reproductive organ The external genitalia are the outer sex organs, such as the penis or vulva in mammals. http://purl.obolibrary.org/obo/GO_0061117 negative regulation of heart growth http://purl.obolibrary.org/obo/GO_0060420 regulation of heart growth Any process that decreases the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart. http://purl.obolibrary.org/obo/UBERON_0004177 hemopoietic organ http://purl.obolibrary.org/obo/UBERON_0000062 organ Organ that is part of the hematopoietic system. http://purl.obolibrary.org/obo/GO_0061130 pancreatic bud formation http://purl.obolibrary.org/obo/GO_0061114 branching involved in pancreas morphogenesis The morphogenetic process in which the foregut region specified to become the pancreas forms a bud. http://purl.obolibrary.org/obo/UBERON_0004178 aorta smooth muscle tissue http://purl.obolibrary.org/obo/UBERON_0004695 arterial system smooth muscle The nonstriated, involuntary muscle tissue located in the wall of the aorta. http://purl.obolibrary.org/obo/GO_0061140 lung secretory cell differentiation http://purl.obolibrary.org/obo/GO_0060487 lung epithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a lung secretory cell. A lung secretory cell is a specialized epithelial cell of the lung that contains large secretory granules in its apical part. http://purl.obolibrary.org/obo/UBERON_0004179 prostate glandular acinus http://purl.obolibrary.org/obo/UBERON_0009842 glandular acinus A saclike structure of the prostate gland, comprised of at least three cell layers: an innermost layer of secretory columnar luminal epithelium, a middle layer of squamous basal epithelium that also contains neuroendocrine cells, transit amplifying cells, and stem cells, and an outer layer of smooth muscle intermixed with other stromal cells. http://purl.obolibrary.org/obo/GO_0061141 lung ciliated cell differentiation http://purl.obolibrary.org/obo/GO_0060487 lung epithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a lung ciliated cell. A lung ciliated cell is a specialized lung epithelial cell that contains cilia for moving substances released from lung secretory cells. http://purl.obolibrary.org/obo/UBERON_0004180 mammary gland fat http://purl.obolibrary.org/obo/UBERON_0003584 mammary gland connective tissue The mammary fat is an adipose structure in the gland that is invaded by the mammary ducts. http://purl.obolibrary.org/obo/GO_0061146 Peyer's patch morphogenesis http://purl.obolibrary.org/obo/GO_0048729 tissue morphogenesis The process in which a Peyer's patch is generated and organized. Peyer's patches are typically found as nodules associated with gut epithelium with distinct internal structures including B- and T-zones for the activation of lymphocytes. http://purl.obolibrary.org/obo/UBERON_0004182 mammary gland cord http://purl.obolibrary.org/obo/UBERON_0034969 epithelial layer of duct The solid cord of epithelial cells that emerges from the mammary bud and grows down from the primary mammary mesenchyme and into a second stromal compartment, the fat pad precursor, beneath the dermis. http://purl.obolibrary.org/obo/GO_0061147 endocardial endothelium development http://purl.obolibrary.org/obo/GO_0003158 endothelium development The progression of the endocardial endothelium over time, from its initial formation to the mature structure. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers. http://purl.obolibrary.org/obo/UBERON_0004183 placental labyrinth blood vessel http://purl.obolibrary.org/obo/UBERON_0022358 placenta blood vessel The embryonic vessels grow through the layer to come in close contact with the maternal blood supply. http://purl.obolibrary.org/obo/GO_0061148 extracellular matrix organization involved in endocardium development http://purl.obolibrary.org/obo/GO_0030198 extracellular matrix organization A process which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix of the endocardium. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers. http://purl.obolibrary.org/obo/UBERON_0004184 prostate gland stroma http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure The prostate gland stroma is made up of the mesenchymal or fibroblast cells of the prostate gland. http://purl.obolibrary.org/obo/GO_0061152 trachea submucosa development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the trachea submucosa over time from its formation to the mature structure. The trachea submucosa is made up of the glands and elastic tissue that lie under the mucosa in the trachea. http://purl.obolibrary.org/obo/UBERON_0004185 endodermal part of digestive tract http://purl.obolibrary.org/obo/UBERON_0004921 subdivision of digestive tract A portions of the gut that is derived from endoderm. http://purl.obolibrary.org/obo/GO_0061153 trachea gland development http://purl.obolibrary.org/obo/GO_0048732 gland development The progression of a trachea gland over time, from its formation to the mature structure. Trachea glands are found under the mucus of the trachea and secrete mucus, and agents that help protect the lung from injury and infection. http://purl.obolibrary.org/obo/UBERON_0004186 olfactory bulb mitral cell layer http://purl.obolibrary.org/obo/UBERON_0004001 olfactory bulb layer The mitral cell layer is composed of pyramidal neurons whose cell bodies are located between the granule cell layer and the plexiform layer. http://purl.obolibrary.org/obo/GO_0061154 endothelial tube morphogenesis http://purl.obolibrary.org/obo/GO_0060562 epithelial tube morphogenesis The process in which the anatomical structures of a tube are generated and organized from an endothelium. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells. http://purl.obolibrary.org/obo/UBERON_0004188 glomerular epithelium http://purl.obolibrary.org/obo/UBERON_0004211 nephron epithelium The glomerular epithelium is an epithelial tissue that covers the outer surfaces of the glomerulus. The glomerular epithelium consists of both parietal and visceral epithelium. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros. http://purl.obolibrary.org/obo/GO_0061155 pulmonary artery endothelial tube morphogenesis http://purl.obolibrary.org/obo/GO_0061154 endothelial tube morphogenesis The process in which the anatomical structures of a tube are generated and organized from the pulmonary artery endothelium. An pulmonary artery endothelium is an epithelium that lines the pulmonary artery. http://purl.obolibrary.org/obo/UBERON_0004189 glomerular endothelium http://purl.obolibrary.org/obo/UBERON_0004852 cardiovascular system endothelium The glomerular endothelium is an epithelial tissue that covers the internal surfaces of the glomerulus. http://purl.obolibrary.org/obo/GO_0061156 pulmonary artery morphogenesis http://purl.obolibrary.org/obo/GO_0048844 artery morphogenesis The process in which the anatomical structures of the pulmonary artery are generated and organized. The pulmonary artery is the artery that carries blood from the heart to the lungs. http://purl.obolibrary.org/obo/UBERON_0004190 renal glomerulus vasculature http://purl.obolibrary.org/obo/UBERON_0006544 kidney vasculature The glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the glomerulus. http://purl.obolibrary.org/obo/GO_0061168 regulation of hair follicle placode formation http://purl.obolibrary.org/obo/GO_0022603 regulation of anatomical structure morphogenesis Any process that modulates the rate, frequency, or extent of hair follicle placode formation, the developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud. http://purl.obolibrary.org/obo/UBERON_0004193 loop of Henle ascending limb thin segment http://purl.obolibrary.org/obo/UBERON_0007685 region of nephron tubule A sub-portion of the loop of Henle in the nephron of the kidney that is permeable to ions but not to water. http://purl.obolibrary.org/obo/GO_0061169 positive regulation of hair placode formation http://purl.obolibrary.org/obo/GO_0061168 regulation of hair follicle placode formation Any process that increases the rate, frequency, or extent of hair follicle placode formation, the developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud. http://purl.obolibrary.org/obo/UBERON_0004194 long nephron http://purl.obolibrary.org/obo/UBERON_0001285 nephron Long nephrons are associated with juxtamedullary glomeruli and extend to the inner medulla. http://purl.obolibrary.org/obo/GO_0061170 negative regulation of hair follicle placode formation http://purl.obolibrary.org/obo/GO_0061168 regulation of hair follicle placode formation Any process that decreases the rate, frequency, or extent of hair follicle placode formation, the developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud. http://purl.obolibrary.org/obo/UBERON_0004195 short nephron http://purl.obolibrary.org/obo/UBERON_0001285 nephron Short nephrons are associated with mid-cortical glomeruli, and have no short ascending limb, so the limb is situated in the outer medulla. http://purl.obolibrary.org/obo/GO_0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus http://purl.obolibrary.org/obo/GO_0061178 regulation of insulin secretion involved in cellular response to glucose stimulus Any process that decreases the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose. http://purl.obolibrary.org/obo/UBERON_0004196 proximal convoluted tubule segment 1 http://purl.obolibrary.org/obo/UBERON_0006555 excretory tube The S1 portion is the initial portion of the proximal convoluted tubule and is responsible for avid reabsorption of water and solutes[GO]. http://purl.obolibrary.org/obo/GO_0061181 regulation of chondrocyte development http://purl.obolibrary.org/obo/GO_0060284 regulation of cell development Any process that modulates the rate, frequency, or extent of the process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate. http://purl.obolibrary.org/obo/UBERON_0004197 proximal convoluted tubule segment 2 http://purl.obolibrary.org/obo/UBERON_0006555 excretory tube The S2 portion of the tubule is involved in reabsorption of water and sodium chloride[GO]. http://purl.obolibrary.org/obo/GO_0061182 negative regulation of chondrocyte development http://purl.obolibrary.org/obo/GO_0061181 regulation of chondrocyte development Any process that decreases the rate, frequency, or extent of the process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate. http://purl.obolibrary.org/obo/UBERON_0004198 comma-shaped body http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure The comma-shaped body is the precursor structure to the S-shaped body that contributes to the morphogenesis of the nephron. http://purl.obolibrary.org/obo/GO_0061183 regulation of dermatome development http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin. http://purl.obolibrary.org/obo/UBERON_0004199 S-shaped body http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure The S-shaped body is the successor of the comma-shaped body that contributes to the morphogenesis of the nephron. http://purl.obolibrary.org/obo/GO_0061184 positive regulation of dermatome development http://purl.obolibrary.org/obo/GO_0061183 regulation of dermatome development Any process that increases the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin. http://purl.obolibrary.org/obo/UBERON_0004200 kidney pyramid http://purl.obolibrary.org/obo/UBERON_0000064 organ part Kidney pyramids are the conical arrangements of tubules that constitute the renal medulla in a multi-lobed mammalian kidney; they contain the loops of Henle and the medullary collecting ducts. http://purl.obolibrary.org/obo/GO_0061185 negative regulation of dermatome development http://purl.obolibrary.org/obo/GO_0061183 regulation of dermatome development Any process that decreases the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin. http://purl.obolibrary.org/obo/UBERON_0004201 kidney outer medulla inner stripe http://purl.obolibrary.org/obo/UBERON_0010000 multicellular anatomical structure The inner stripe is a deep, centrally located portion of the renal outer medulla and is traversed by thick and thin portions of nephron tubules. http://purl.obolibrary.org/obo/GO_0061189 positive regulation of sclerotome development http://purl.obolibrary.org/obo/GO_0061190 regulation of sclerotome development Any process that increases the rate, frequency, or extent of the progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra. http://purl.obolibrary.org/obo/UBERON_0004202 kidney outer medulla outer stripe http://purl.obolibrary.org/obo/UBERON_0010000 multicellular anatomical structure The outer stripe is the region of the kidney that lies distal to the line of termination of the straight renal tubules. http://purl.obolibrary.org/obo/GO_0061190 regulation of sclerotome development http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the rate, frequency, or extent of the progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra. http://purl.obolibrary.org/obo/UBERON_0004203 cortical collecting duct http://purl.obolibrary.org/obo/UBERON_0013522 subdivision of tube The cortical collecting duct is the portion of the collecting duct that resides in the renal cortex. http://purl.obolibrary.org/obo/UBERON_0004204 outer medullary collecting duct http://purl.obolibrary.org/obo/UBERON_0001232 collecting duct of renal tubule The outer medullary collecting duct is the portion of the collecting duct that lies in the renal outer medulla. http://purl.obolibrary.org/obo/GO_0061193 taste bud development http://purl.obolibrary.org/obo/GO_0007423 sensory organ development The progression of the taste bud over time, from its formation to the mature state. The taste bud is a specialized area of the tongue that contains taste receptors. http://purl.obolibrary.org/obo/UBERON_0004205 inner medullary collecting duct http://purl.obolibrary.org/obo/UBERON_0001232 collecting duct of renal tubule The inner medullary collecting duct is the portion of the collecting duct that lies in the renal inner medulla. http://purl.obolibrary.org/obo/GO_0061194 taste bud morphogenesis http://purl.obolibrary.org/obo/GO_0090596 sensory organ morphogenesis The process in which the anatomical structures of the taste bud are generated and organized. The taste bud is a specialized area of the tongue that contains taste receptors. http://purl.obolibrary.org/obo/UBERON_0004208 nephrogenic mesenchyme http://purl.obolibrary.org/obo/UBERON_0003104 mesenchyme Nephrogenic mesenchyme is the tissue made up of loosely connected mesenchymal cells in the nephron. http://purl.obolibrary.org/obo/UBERON_0004209 renal vesicle http://purl.obolibrary.org/obo/UBERON_0007503 epithelial vesicle The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells. http://purl.obolibrary.org/obo/GO_0061195 taste bud formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The developmental process pertaining to the initial formation of the taste bud from unspecified parts. The taste bud is a specialized area of the tongue that contains taste receptors. http://purl.obolibrary.org/obo/UBERON_0004211 nephron epithelium http://purl.obolibrary.org/obo/UBERON_0004819 kidney epithelium The nephron epithelium is a tissue that covers the surface of a nephron. http://purl.obolibrary.org/obo/GO_0061205 paramesonephric duct development http://purl.obolibrary.org/obo/GO_0003006 developmental process involved in reproduction The process whose specific outcome is the progression of the paramesonephric duct over time, from its formation to the mature structure. Mullerian ducts (or paramesonephric ducts) are paired ducts of the embryo that run down the lateral sides of the urogenital ridge and terminate at the mullerian eminence in the primitive urogenital sinus. In the female, they will develop to form the fallopian tubes, uterus, cervix, and the upper portion of the vagina; in the male, they are lost. These ducts are made of tissue of mesodermal origin. http://purl.obolibrary.org/obo/UBERON_0004212 glomerular capillary http://purl.obolibrary.org/obo/UBERON_0003527 kidney capillary The small branching blood vessels in the kidney glomerulus that receives blood from the kidney afferent arterioles; these capillaries are under high pressure for filtering within the glomerulus. http://purl.obolibrary.org/obo/GO_0061206 mesonephros morphogenesis http://purl.obolibrary.org/obo/GO_0060993 kidney morphogenesis The process in which the anatomical structures of the mesonephros are generated and organized. http://purl.obolibrary.org/obo/UBERON_0004214 upper leg nerve http://purl.obolibrary.org/obo/UBERON_0003431 leg nerve A nerve that is part of a hindlimb stylopod [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0061211 mesonephric collecting duct development http://purl.obolibrary.org/obo/GO_0072044 collecting duct development The process whose specific outcome is the progression of a collecting duct in the mesonephros over time, from its formation to the mature structure. The collecting duct regulates water, electrolyte and acid-base balance. The collecting duct is the final common path through which urine flows before entering the ureter and then emptying into the bladder. http://purl.obolibrary.org/obo/UBERON_0004215 back nerve http://purl.obolibrary.org/obo/UBERON_0001021 nerve A nerve that is part of a back [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004216 lower arm nerve http://purl.obolibrary.org/obo/UBERON_0003433 arm nerve A nerve that is part of a lower arm [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0061212 mesonephric juxtaglomerular apparatus development http://purl.obolibrary.org/obo/GO_0072051 juxtaglomerular apparatus development The process whose specific outcome is the progression of the juxtaglomerular apparatus in the mesonephros over time, from its formation to the mature structure. The juxtaglomerular apparatus is an anatomical structure which consists of juxtaglomerular cells, extraglomerular mesangial cells and the macula densa. The juxtaglomerular apparatus lies adjacent to the glomerulus and regulates kidney function by maintaining the blood flow to the kidney and the filtration rate. http://purl.obolibrary.org/obo/UBERON_0004217 upper arm nerve http://purl.obolibrary.org/obo/UBERON_0003433 arm nerve A nerve that is part of a forelimb stylopod [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0061213 positive regulation of mesonephros development http://purl.obolibrary.org/obo/GO_0090184 positive regulation of kidney development Any process that increases the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine. http://purl.obolibrary.org/obo/UBERON_0004218 lower leg nerve http://purl.obolibrary.org/obo/UBERON_0003431 leg nerve A nerve that is part of a lower leg [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0061214 mesonephric smooth muscle tissue development http://purl.obolibrary.org/obo/GO_0072194 kidney smooth muscle tissue development The process whose specific outcome is the progression of smooth muscle in the mesonephros over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/UBERON_0004219 urethra smooth muscle layer http://purl.obolibrary.org/obo/UBERON_0001135 smooth muscle tissue A portion of smooth muscle tissue that is part of a urethra [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0061215 mesonephric nephron development http://purl.obolibrary.org/obo/GO_0072006 nephron development The process whose specific outcome is the progression of a nephron in the mesonephros over time, from its formation to the mature structure. A nephron is the functional unit of the kidney. http://purl.obolibrary.org/obo/UBERON_0004220 large intestine smooth muscle http://purl.obolibrary.org/obo/UBERON_0004221 intestine smooth muscle A portion of smooth muscle tissue that is part of a large intestine [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0061217 regulation of mesonephros development http://purl.obolibrary.org/obo/GO_0090183 regulation of kidney development Any process that modulates the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine. http://purl.obolibrary.org/obo/GO_0061218 negative regulation of mesonephros development http://purl.obolibrary.org/obo/GO_0090185 negative regulation of kidney development Any process that decreases the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine. http://purl.obolibrary.org/obo/GO_0061219 mesonephric mesenchyme development http://purl.obolibrary.org/obo/GO_0072074 kidney mesenchyme development The biological process whose specific outcome is the progression of a mesonephric mesenchyme from an initial condition to its mature state. This process begins with the formation of mesonephric mesenchyme and ends with the mature structure. Mesonephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the mesonephros. http://purl.obolibrary.org/obo/GO_0061220 mesonephric macula densa development http://purl.obolibrary.org/obo/GO_0072024 macula densa development The process whose specific outcome is the progression of the mesonephric macula densa over time, from its formation to the mature structure. The mesonephric macula densa is an area of specialized cells in the distal tubule of the mesonephros that makes contact with the vascular pole of the glomerulus. http://purl.obolibrary.org/obo/GO_0061221 mesonephric mesenchyme morphogenesis http://purl.obolibrary.org/obo/GO_0072131 kidney mesenchyme morphogenesis The process in which the anatomical structures of a mesonephric mesenchymal tissue are generated and organized. Mesonephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the mesonephros. http://purl.obolibrary.org/obo/GO_0061224 mesonephric glomerulus development http://purl.obolibrary.org/obo/GO_0032835 glomerulus development The progression of the mesonephric glomerulus over time from its initial formation until its mature state. The mesonephric glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the mature vertebrate kidney, or mesonephros. http://purl.obolibrary.org/obo/GO_0061228 mesonephric nephron morphogenesis http://purl.obolibrary.org/obo/GO_0072028 nephron morphogenesis The process in which the anatomical structures of the mesonephric nephron are generated and organized. A mesonephric nephron is the functional unit of the mesonephros. http://purl.obolibrary.org/obo/GO_0061231 mesonephric glomerulus vasculature development http://purl.obolibrary.org/obo/GO_0072012 glomerulus vasculature development The biological process whose specific outcome is the progression of a mesonephric glomerulus vasculature from an initial condition to its mature state. This process begins with the formation of the mesonephric glomerulus vasculature and ends with the mature structure. The mesonephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the mesonephric glomerulus. http://purl.obolibrary.org/obo/GO_0061232 mesonephric glomerular epithelium development http://purl.obolibrary.org/obo/GO_0072010 glomerular epithelium development The process whose specific outcome is the progression of the mesonephric glomerular epithelium over time, from its formation to the mature structure. The mesonephric glomerular epithelium is an epithelial tissue that covers the outer surfaces of the glomerulus in the mesonephros. The mesonephric glomerular epithelium consists of both parietal and visceral epithelium. Mesonephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the mesonephros. http://purl.obolibrary.org/obo/UBERON_0004221 intestine smooth muscle http://purl.obolibrary.org/obo/UBERON_0004226 gastrointestinal system smooth muscle A portion of smooth muscle tissue that is part of a intestine [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0061234 mesonephric glomerulus morphogenesis http://purl.obolibrary.org/obo/GO_0072102 glomerulus morphogenesis The process in which the anatomical structures of the mesonephric glomerulus are generated and organized. The mesonephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate mesonephros. http://purl.obolibrary.org/obo/UBERON_0004222 stomach smooth muscle http://purl.obolibrary.org/obo/UBERON_0004226 gastrointestinal system smooth muscle A portion of smooth muscle tissue that is part of a stomach [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0061236 mesonephric comma-shaped body morphogenesis http://purl.obolibrary.org/obo/GO_0072049 comma-shaped body morphogenesis The process in which the mesonephric comma-shaped body is generated and organized. The mesonephric comma-shaped body is the precursor structure to the mesonephric S-shaped body that contributes to the morphogenesis of a nephron in the mesonephros. http://purl.obolibrary.org/obo/UBERON_0004223 vagina smooth muscle http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure A portion of smooth muscle tissue that is part of a vagina [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0061240 mesonephric nephron tubule morphogenesis http://purl.obolibrary.org/obo/GO_0072171 mesonephric tubule morphogenesis The process in which the anatomical structures of a mesonephric nephron tubule are generated and organized. A mesonephric nephron tubule is an epithelial tube that is part of the mesonephric nephron, the functional part of the mesonephros. http://purl.obolibrary.org/obo/UBERON_0004224 muscular coat of vas deferens http://purl.obolibrary.org/obo/UBERON_0034933 layer of smooth muscle tissue A muscular coat that is part of a vas deferens [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0061241 mesonephric nephron epithelium development http://purl.obolibrary.org/obo/GO_0072163 mesonephric epithelium development The process whose specific outcome is the progression of the mesonephric nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The mesonephric nephron epithelium is a tissue that covers the surface of a nephron in the mesonephros. http://purl.obolibrary.org/obo/UBERON_0004225 respiratory system smooth muscle http://purl.obolibrary.org/obo/UBERON_0001135 smooth muscle tissue A portion of smooth muscle tissue that is part of a respiratory system [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0061242 mesonephric nephron tubule development http://purl.obolibrary.org/obo/GO_0061241 mesonephric nephron epithelium development The progression of a mesonephric nephron tubule over time, from its initial formation to the mature structure. A mesonephric nephron tubule is an epithelial tube that is part of the mesonephric nephron, the functional part of the mesonephros. http://purl.obolibrary.org/obo/UBERON_0004226 gastrointestinal system smooth muscle http://purl.obolibrary.org/obo/UBERON_0001135 smooth muscle tissue A portion of smooth muscle tissue that is part of a digestive system [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0061243 mesonephric renal vesicle morphogenesis http://purl.obolibrary.org/obo/GO_0072077 renal vesicle morphogenesis The process in which the anatomical structures of the mesonephric renal vesicle are generated and organized. The renal vesicle is the primordial structure of the mesonephric nephron epithelium, and is formed by the condensation of mesenchymal cells. http://purl.obolibrary.org/obo/UBERON_0004227 kidney pelvis smooth muscle http://purl.obolibrary.org/obo/UBERON_0001135 smooth muscle tissue The smooth muscle tissue surrounding the urothelium of the kidney pelvis. http://purl.obolibrary.org/obo/GO_0061244 mesonephric S-shaped body morphogenesis http://purl.obolibrary.org/obo/GO_0072050 S-shaped body morphogenesis The process in which the mesonephric S-shaped body is generated and organized. The mesonephric S-shaped body is the successor of the mesonephric comma-shaped body that contributes to the morphogenesis of a nephron in the mesonephros. http://purl.obolibrary.org/obo/UBERON_0004228 urinary bladder smooth muscle http://purl.obolibrary.org/obo/UBERON_0001135 smooth muscle tissue A portion of smooth muscle tissue that is part of a urinary bladder [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0061247 mesonephric glomerular mesangium development http://purl.obolibrary.org/obo/GO_0072109 glomerular mesangium development The process whose specific outcome is the progression of the mesonephric glomerular mesangium over time, from its formation to the mature structure. The mesonephric glomerular mesangium is the thin membrane connective tissue composed of mesangial cells in the mesonephros, which helps to support the capillary loops in a renal glomerulus. http://purl.obolibrary.org/obo/UBERON_0004229 urinary bladder trigone smooth muscle http://purl.obolibrary.org/obo/UBERON_0004228 urinary bladder smooth muscle A portion of smooth muscle tissue that is part of a trigone of urinary bladder [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0061248 mesonephric glomerulus vasculature morphogenesis http://purl.obolibrary.org/obo/GO_0072103 glomerulus vasculature morphogenesis The process in which the anatomical structures of the mesonephric glomerulus vasculature are generated and organized. The mesonephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the mesonephric glomerulus. http://purl.obolibrary.org/obo/GO_0061249 mesonephric glomerular capillary formation http://purl.obolibrary.org/obo/GO_0072104 glomerular capillary formation The process that gives rise to a mesonephric glomerular capillary. This process pertains to the initial formation of a structure from unspecified parts. http://purl.obolibrary.org/obo/UBERON_0004230 urinary bladder neck smooth muscle http://purl.obolibrary.org/obo/UBERON_0004228 urinary bladder smooth muscle A portion of smooth muscle tissue that is part of a neck of urinary bladder [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0061250 mesonephric glomerular epithelial cell differentiation http://purl.obolibrary.org/obo/GO_0072311 glomerular epithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a mesonephric glomerular epithelial cell. Mesonephric glomerular epithelial cells are specialized epithelial cells that form part of the mesonephric glomerulus; there are two types, mesonephric glomerular parietal epithelial cells and mesonephric glomerular visceral epithelial cells. http://purl.obolibrary.org/obo/UBERON_0004231 anal region smooth muscle http://purl.obolibrary.org/obo/UBERON_0001135 smooth muscle tissue A portion of smooth muscle tissue that is part of an anal region [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0061251 mesonephric glomerular epithelial cell development http://purl.obolibrary.org/obo/GO_0072310 glomerular epithelial cell development The process whose specific outcome is the progression of a mesonephric glomerular epithelial cell over time, from its formation to the mature structure. Mesonephric glomerular epithelial cells are specialized epithelial cells that form part of the mesonephric glomerulus; there are two types, mesonephric glomerular parietal epithelial cells and mesonephric glomerular visceral epithelial cells. http://purl.obolibrary.org/obo/UBERON_0004232 lymphatic vessel smooth muscle http://purl.obolibrary.org/obo/UBERON_0001135 smooth muscle tissue A portion of smooth muscle tissue that is part of a lymphatic vessel [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0061256 mesonephric podocyte differentiation http://purl.obolibrary.org/obo/GO_0072112 podocyte differentiation The process in which a relatively unspecialized cell acquires specialized features of a mesonephric glomerular visceral epithelial cell. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the mesonephros. http://purl.obolibrary.org/obo/UBERON_0004233 lower respiratory tract smooth muscle http://purl.obolibrary.org/obo/UBERON_0004225 respiratory system smooth muscle A portion of smooth muscle tissue that is part of a lower respiratory tract [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0061257 mesonephric podocyte development http://purl.obolibrary.org/obo/GO_0072015 podocyte development The process whose specific outcome is the progression of a mesonephric glomerular visceral epithelial cell over time, from its formation to the mature structure. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the mesonephros. http://purl.obolibrary.org/obo/UBERON_0004234 iris smooth muscle http://purl.obolibrary.org/obo/UBERON_0003386 smooth muscle of eye A portion of smooth muscle tissue that is part of a iris [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0061262 mesonephric renal vesicle formation http://purl.obolibrary.org/obo/GO_0072033 renal vesicle formation The developmental process pertaining to the initial formation of the mesonephros. http://purl.obolibrary.org/obo/UBERON_0004235 mammary gland smooth muscle http://purl.obolibrary.org/obo/UBERON_0001135 smooth muscle tissue A portion of smooth muscle tissue that is part of a mammary gland [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0061265 mesonephric nephron tubule epithelial cell differentiation http://purl.obolibrary.org/obo/GO_0072160 nephron tubule epithelial cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the mesonephric nephron tubule as it progresses from its formation to the mature state. http://purl.obolibrary.org/obo/GO_0061272 mesonephric connecting tubule development http://purl.obolibrary.org/obo/GO_0072027 connecting tubule development The process whose specific outcome is the progression of the mesonephric connecting tubule over time, from its formation to the mature structure. The mesonephric connecting tubule is a tubular segment of the mesonephric nephron; it connects the distal tubule to the collecting duct in the mesonephros. http://purl.obolibrary.org/obo/GO_0061273 mesonephric distal tubule morphogenesis http://purl.obolibrary.org/obo/GO_0061240 mesonephric nephron tubule morphogenesis The process in which the anatomical structures of a mesonephric distal tubule are generated and organized. The mesonephric distal tubule is a mesonephric nephron tubule that begins at the macula densa and extends to the mesonephric connecting tubule. http://purl.obolibrary.org/obo/GO_0061274 mesonephric distal tubule development http://purl.obolibrary.org/obo/GO_0061242 mesonephric nephron tubule development The process whose specific outcome is the progression of the mesonephric distal tubule over time, from its formation to the mature structure. The mesonephric distal tubule is a mesonephric nephron tubule that begins at the terminal segment of the proximal tubule and ends at the mesonephric connecting tubule. http://purl.obolibrary.org/obo/GO_0061275 mesonephric proximal tubule development http://purl.obolibrary.org/obo/GO_0061242 mesonephric nephron tubule development The progression of the mesonephric proximal tubule over time, from its formation to the mature structure. The mesonephric proximal tubule extends from the capsule to the distal tubule. http://purl.obolibrary.org/obo/UBERON_0004236 arteriole smooth muscle http://purl.obolibrary.org/obo/UBERON_0004695 arterial system smooth muscle A portion of smooth muscle tissue that is part of an arteriole [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0061276 mesonephric proximal tubule morphogenesis http://purl.obolibrary.org/obo/GO_0061240 mesonephric nephron tubule morphogenesis The process in which the anatomical structures of a mesonephric proximal tubule are generated and organized. The mesonephric proximal tubule extends from the capsule to the distal tubule. http://purl.obolibrary.org/obo/UBERON_0004237 blood vessel smooth muscle http://purl.obolibrary.org/obo/UBERON_0001135 smooth muscle tissue Smooth muscle found within, and composing the majority of the wall of blood vessels. http://purl.obolibrary.org/obo/GO_0061277 mesonephric nephron tubule formation http://purl.obolibrary.org/obo/GO_0072172 mesonephric tubule formation The developmental process pertaining to the initial formation of a mesonephric nephron tubule from unspecified parts. A mesonephric nephron tubule is an epithelial tube that is part of a nephron in the mesonephros. http://purl.obolibrary.org/obo/UBERON_0004238 spleen smooth muscle http://purl.obolibrary.org/obo/UBERON_0001135 smooth muscle tissue A portion of smooth muscle tissue that is part of a spleen [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0061285 mesonephric capsule development http://purl.obolibrary.org/obo/GO_0072127 renal capsule development The progression of the mesonephric capsule over time, from its formation to the mature structure. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue. http://purl.obolibrary.org/obo/UBERON_0004239 small intestine smooth muscle http://purl.obolibrary.org/obo/UBERON_0004221 intestine smooth muscle A portion of smooth muscle tissue that is part of a small intestine [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0061286 mesonephric capsule morphogenesis http://purl.obolibrary.org/obo/GO_0072128 renal capsule morphogenesis The process in which the anatomical structures of the mesonephric capsule are generated and organized. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. http://purl.obolibrary.org/obo/UBERON_0004240 gallbladder smooth muscle http://purl.obolibrary.org/obo/UBERON_0001135 smooth muscle tissue A portion of smooth muscle tissue that is part of a gallbladder [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0061287 mesonephric capsule formation http://purl.obolibrary.org/obo/GO_0072129 renal capsule formation The developmental process pertaining to the initial formation of a mesonephric capsule from unspecified parts. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. http://purl.obolibrary.org/obo/UBERON_0004242 bronchus smooth muscle http://purl.obolibrary.org/obo/UBERON_0004233 lower respiratory tract smooth muscle A portion of smooth muscle tissue that is part of a bronchus [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0061298 retina vasculature development in camera-type eye http://purl.obolibrary.org/obo/GO_0001944 vasculature development The process whose specific outcome is the progression of the vasculature of the retina over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/UBERON_0004243 prostate gland smooth muscle http://purl.obolibrary.org/obo/UBERON_0008715 muscle tissue of prostate A portion of smooth muscle tissue that is part of a prostate gland [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0061299 retina vasculature morphogenesis in camera-type eye http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the vasculature of the retina is generated and organized. http://purl.obolibrary.org/obo/UBERON_0004245 oviduct smooth muscle http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure A portion of smooth muscle tissue that is part of a fallopian tube [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0061300 cerebellum vasculature development http://purl.obolibrary.org/obo/GO_0001944 vasculature development The process whose specific outcome is the progression of the vasculature of the cerebellum over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/UBERON_0004246 outflow tract smooth muscle http://purl.obolibrary.org/obo/UBERON_0001135 smooth muscle tissue A portion of smooth muscle tissue that is part of a outflow tract [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0061301 cerebellum vasculature morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the vasculature of the cerebellum is generated and organized. http://purl.obolibrary.org/obo/UBERON_0004247 bone of dorsum http://purl.obolibrary.org/obo/UBERON_0005174 dorsal region element A bone that is part of the dorsal region of an animal. http://purl.obolibrary.org/obo/GO_0061304 retinal blood vessel morphogenesis http://purl.obolibrary.org/obo/GO_0061299 retina vasculature morphogenesis in camera-type eye The process whose specific outcome is the progression of a blood vessel of the retina over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/UBERON_0004248 pedal digit bone http://purl.obolibrary.org/obo/UBERON_0012359 pedal digitopodium bone A bone that is part of a hindlimb digit. Typically phalanges but may include sesamoids. http://purl.obolibrary.org/obo/GO_0061307 cardiac neural crest cell differentiation involved in heart development http://purl.obolibrary.org/obo/GO_0014033 neural crest cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a cardiac neural crest cell that will migrate to the heart and contribute to its development. Cardiac neural crest cells are specialized cells that migrate toward the heart from the third, fourth and sixth pharyngeal arches. http://purl.obolibrary.org/obo/UBERON_0004249 manual digit bone http://purl.obolibrary.org/obo/UBERON_0012358 manual digitopodium bone A bone that is part of a forelimb digit. Typically phalanges but may include sesamoids. http://purl.obolibrary.org/obo/GO_0061318 renal filtration cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a renal filtration cell. Renal filtration cells are specialized cells of the renal system that filter fluids by charge, size or both. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. http://purl.obolibrary.org/obo/UBERON_0004250 upper arm bone http://purl.obolibrary.org/obo/UBERON_0003460 arm bone A bone that is part of a forelimb stylopod [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0061319 nephrocyte differentiation http://purl.obolibrary.org/obo/GO_0061318 renal filtration cell differentiation The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a nephrocyte. A nephrocyte is an insect renal cell that filters hemolymph. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. http://purl.obolibrary.org/obo/UBERON_0004251 hindlimb zeugopod bone http://purl.obolibrary.org/obo/UBERON_0005893 leg bone A bone that is part of a lower leg [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0061322 disseminated nephrocyte differentiation http://purl.obolibrary.org/obo/GO_0061319 nephrocyte differentiation The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a disseminated nephrocyte. A disseminated nephrocyte is an insect renal cell that filters hemolymph and is found at scattered locations in the fat body or other tissues. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. http://purl.obolibrary.org/obo/UBERON_0004252 hindlimb stylopod muscle http://purl.obolibrary.org/obo/UBERON_0001383 muscle of leg Any muscle organ that is part of a hindlimb stylopod (upper leg)[Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0061325 cell proliferation involved in outflow tract morphogenesis http://purl.obolibrary.org/obo/GO_0061323 cell proliferation involved in heart morphogenesis The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to the shaping of the outflow tract. http://purl.obolibrary.org/obo/UBERON_0004253 skin muscle http://purl.obolibrary.org/obo/UBERON_0001630 muscle organ Any muscle organ that is part of a skin of body [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0061326 renal tubule development http://purl.obolibrary.org/obo/GO_0060429 epithelium development The progression of the renal tubule over time from its formation to the mature form. A renal tubule is a tube that filters, re-absorbs and secretes substances to rid an organism of waste and to play a role in fluid homeostasis. http://purl.obolibrary.org/obo/UBERON_0004254 forelimb zeugopod muscle http://purl.obolibrary.org/obo/UBERON_0001499 muscle of arm Any muscle organ that is part of a forelimb zeugopod (lower arm)[Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0061330 Malpighian tubule stellate cell differentiation http://purl.obolibrary.org/obo/GO_0030855 epithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a Malpighian tubule stellate cell. A Malpighian tubule stellate cell is a specialized epithelial secretory cell that moves chloride ions and water across the tubule epithelium. http://purl.obolibrary.org/obo/UBERON_0004255 forelimb stylopod muscle http://purl.obolibrary.org/obo/UBERON_0001499 muscle of arm Any muscle organ that is part of a forelimb stylopod (upper arm)[Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0061331 epithelial cell proliferation involved in Malpighian tubule morphogenesis http://purl.obolibrary.org/obo/GO_2001013 epithelial cell proliferation involved in renal tubule morphogenesis The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population and contributing to the shaping of a Malpighian tubule. http://purl.obolibrary.org/obo/UBERON_0004256 hindlimb zeugopod muscle http://purl.obolibrary.org/obo/UBERON_0001383 muscle of leg Any muscle organ that is part of a hindlimb zeugopod (lower leg) [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0061332 Malpighian tubule bud morphogenesis http://purl.obolibrary.org/obo/GO_0060572 morphogenesis of an epithelial bud The morphogenetic process in which a bud forms from the embryonic hindgut tube to form the Malpighian tubule. A bud is a protrusion that forms from the tube by localized changes in cell shape and position. http://purl.obolibrary.org/obo/GO_0061334 cell rearrangement involved in Malpighian tubule morphogenesis http://purl.obolibrary.org/obo/GO_0016477 cell migration The movement of an epithelial cell with respect to other epithelial cells that contributes to the shaping of the Malpighian tubule. http://purl.obolibrary.org/obo/UBERON_0004257 upper leg blood vessel http://purl.obolibrary.org/obo/UBERON_0003503 leg blood vessel A blood vessel that is part of a hindlimb stylopod [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0061336 cell morphogenesis involved in Malpighian tubule morphogenesis http://purl.obolibrary.org/obo/GO_0000902 cell morphogenesis The shape change of an epithelial cell from a columnar to squamous cell morphology that contributes to the shaping of the Malpighian tubule. http://purl.obolibrary.org/obo/UBERON_0004258 back blood vessel http://purl.obolibrary.org/obo/UBERON_0001981 blood vessel A blood vessel that is part of a back [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0061337 cardiac conduction http://purl.obolibrary.org/obo/GO_0008016 regulation of heart contraction Transfer of an organized electrical impulse across the heart to coordinate the contraction of cardiac muscles. The process begins with generation of an action potential (in the sinoatrial node (SA) in humans) and ends with a change in the rate, frequency, or extent of the contraction of the heart muscles. http://purl.obolibrary.org/obo/UBERON_0004259 lower arm blood vessel http://purl.obolibrary.org/obo/UBERON_0003507 arm blood vessel A blood vessel that is part of a lower arm [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0061344 regulation of cell adhesion involved in heart morphogenesis http://purl.obolibrary.org/obo/GO_0030155 regulation of cell adhesion Any process that modulates the extent of cell adhesion contributing to the shaping of the heart. http://purl.obolibrary.org/obo/UBERON_0004260 upper arm blood vessel http://purl.obolibrary.org/obo/UBERON_0003507 arm blood vessel A blood vessel that is part of a forelimb stylopod [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0061352 cell chemotaxis involved in Malpighian tubule morphogenesis http://purl.obolibrary.org/obo/GO_0061334 cell rearrangement involved in Malpighian tubule morphogenesis The directed movement of the outgrowing Malpighian tubule guided by specific chemical cues/signals. Movement may be towards a guidance cue (positive chemotaxis) or away from it (negative chemotaxis). Guidance contributes to the final positioning of the tubule. http://purl.obolibrary.org/obo/UBERON_0004261 lower leg blood vessel http://purl.obolibrary.org/obo/UBERON_0003503 leg blood vessel A blood vessel that is part of a lower leg [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0061360 optic chiasma development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The developmental process pertaining to the progression of the optic chiasm from its initial formation to the mature structure. The process begins when the pathfinding of the axons of the developing optic nerve cause some axons to cross at the midline of the brain and ends when the axons are mature. http://purl.obolibrary.org/obo/UBERON_0004262 upper leg skin http://purl.obolibrary.org/obo/UBERON_0001511 skin of leg A zone of skin that is part of a hindlimb stylopod [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0061370 testosterone biosynthetic process http://purl.obolibrary.org/obo/GO_0042181 ketone biosynthetic process The chemical reactions and pathways resulting in the formation of testosterone, an androgen having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-4 C-5. http://purl.obolibrary.org/obo/UBERON_0004263 upper arm skin http://purl.obolibrary.org/obo/UBERON_0002427 arm skin A zone of skin that is part of a forelimb stylopod [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0061377 mammary gland lobule development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the mammary gland lobule over time, from its formation to the mature structure. A mammary gland lobule is a small rounded projection of the mammary gland. http://purl.obolibrary.org/obo/UBERON_0004264 lower leg skin http://purl.obolibrary.org/obo/UBERON_0001511 skin of leg A zone of skin that is part of a lower leg [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0061382 Malpighian tubule tip cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a Malpighian tubule tip cell. A Malpighian tubule tip cell is a mitogenic signaling cell that controls the proliferation of its neighboring cells. http://purl.obolibrary.org/obo/UBERON_0004265 outflow tract myocardium http://purl.obolibrary.org/obo/UBERON_0002349 myocardium A myocardium that is part of a outflow tract [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0061383 trabecula morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process of shaping a trabecula in an organ. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue. http://purl.obolibrary.org/obo/UBERON_0004266 upper leg connective tissue http://purl.obolibrary.org/obo/UBERON_0003569 leg connective tissue A portion of connective tissue that is part of a hindlimb stylopod [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0061437 renal system vasculature development http://purl.obolibrary.org/obo/GO_0001944 vasculature development The process whose specific outcome is the progression of vasculature of the renal system over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/UBERON_0004267 back connective tissue http://purl.obolibrary.org/obo/UBERON_0002384 connective tissue A portion of connective tissue that is part of a back [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0061438 renal system vasculature morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the renal system vasculature is generated and organized. Morphogenesis pertains to the creation of form. http://purl.obolibrary.org/obo/UBERON_0004268 lower arm connective tissue http://purl.obolibrary.org/obo/UBERON_0003573 arm connective tissue A portion of connective tissue that is part of a lower arm [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0061439 kidney vasculature morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the kidney vasculature is generated and organized. Morphogenesis pertains to the creation of form. http://purl.obolibrary.org/obo/UBERON_0004269 upper arm connective tissue http://purl.obolibrary.org/obo/UBERON_0003573 arm connective tissue A portion of connective tissue that is part of a forelimb stylopod [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0061440 kidney vasculature development http://purl.obolibrary.org/obo/GO_0061437 renal system vasculature development The process whose specific outcome is the progression of the vasculature of the kidney over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/UBERON_0004270 lower leg connective tissue http://purl.obolibrary.org/obo/UBERON_0003569 leg connective tissue A portion of connective tissue that is part of a lower leg [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0061441 renal artery morphogenesis http://purl.obolibrary.org/obo/GO_0048844 artery morphogenesis The process in which the anatomical structure of a renal artery is generated and organized. Renal arteries supply the kidneys with blood. http://purl.obolibrary.org/obo/UBERON_0004271 outflow tract pericardium http://purl.obolibrary.org/obo/UBERON_0002407 pericardium A pericardium that is part of a outflow tract [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0061449 olfactory bulb tufted cell development http://purl.obolibrary.org/obo/GO_0021884 forebrain neuron development The process whose specific outcome is the progression of an olfactory bulb tufted cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. http://purl.obolibrary.org/obo/UBERON_0004273 cartilaginous joint suture http://purl.obolibrary.org/obo/UBERON_0003685 cranial suture A cranial suture that is part of a cartilaginous joint [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0061450 trophoblast cell migration http://purl.obolibrary.org/obo/GO_0001667 ameboidal-type cell migration Trophoblast cell migration that is accomplished by extension and retraction of a pseudopodium. Trophoblast cells line the outside of the blastocyst. http://purl.obolibrary.org/obo/UBERON_0004274 lateral ventricle choroid plexus epithelium http://purl.obolibrary.org/obo/UBERON_0003911 choroid plexus epithelium A choroid plexus epithelium that is part of a lateral ventricle [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0061451 retrotrapezoid nucleus development http://purl.obolibrary.org/obo/GO_0048857 neural nucleus development The progression of the retrotrapezoid nucleus (RTN) over time from it's initial formation to its mature state. The retrotrapezoid nucleus is a group of neurons in the rostral medulla, which are responsible regulating respiration. http://purl.obolibrary.org/obo/UBERON_0004275 third ventricle choroid plexus epithelium http://purl.obolibrary.org/obo/UBERON_0003911 choroid plexus epithelium A choroid plexus epithelium that is part of a third ventricle [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0061452 retrotrapezoid nucleus neuron differentiation http://purl.obolibrary.org/obo/GO_0021953 central nervous system neuron differentiation The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the retrotrapezoid nucleus. http://purl.obolibrary.org/obo/UBERON_0004276 fourth ventricle choroid plexus epithelium http://purl.obolibrary.org/obo/UBERON_0003911 choroid plexus epithelium A choroid plexus epithelium that is part of a fourth ventricle [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0061453 interstitial cell of Cajal differentiation http://purl.obolibrary.org/obo/GO_0060575 intestinal epithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of an interstitial cell of Cajal. An interstitial cell of Cajal is an intestinal neuroepithelial cell that serves as a pacemaker to trigger gut contraction. http://purl.obolibrary.org/obo/UBERON_0004277 eye muscle http://purl.obolibrary.org/obo/UBERON_0001630 muscle organ A muscle that is part of the eye region. http://purl.obolibrary.org/obo/GO_0061454 release of sequestered calcium ion into cytosol by Golgi http://purl.obolibrary.org/obo/GO_0051209 release of sequestered calcium ion into cytosol The directed movement of calcium ions (Ca2+) out of the Golgi apparatus into the cytosol. http://purl.obolibrary.org/obo/GO_0061470 T follicular helper cell differentiation http://purl.obolibrary.org/obo/GO_0042093 T-helper cell differentiation The process in which a relatively unspecialized T cell acquires specialized features of a mature T follicular helper cell. http://purl.obolibrary.org/obo/UBERON_0004288 skeleton http://purl.obolibrary.org/obo/UBERON_0034925 anatomical collection Anatomical cluster that consists of all the skeletal elements (eg., bone, cartilage, and teeth) of the body. http://purl.obolibrary.org/obo/GO_0061484 hematopoietic stem cell homeostasis http://purl.obolibrary.org/obo/GO_0048872 homeostasis of number of cells Any biological process involved in the maintenance of the steady-state number of hematopoietic stem cells within a population of cells. http://purl.obolibrary.org/obo/UBERON_0004290 dermomyotome http://purl.obolibrary.org/obo/UBERON_0016888 transitional anatomical structure The bilaminar epithelium formed from the myotome and dermatome. http://purl.obolibrary.org/obo/GO_0061485 memory T cell proliferation http://purl.obolibrary.org/obo/GO_0042098 T cell proliferation The expansion of a memory T cell population by cell division. http://purl.obolibrary.org/obo/UBERON_0004291 heart rudiment http://purl.obolibrary.org/obo/UBERON_0012275 meso-epithelium A cone-like structure that is formed when myocardial progenitor cells of the heart field fuse at the midline. The heart rudiment is the first structure of the heart tube. http://purl.obolibrary.org/obo/GO_0061512 protein localization to cilium http://purl.obolibrary.org/obo/GO_0033365 protein localization to organelle A process in which a protein is transported to, or maintained in, a location within a cilium. http://purl.obolibrary.org/obo/UBERON_0004292 cardiac skeleton http://purl.obolibrary.org/obo/UBERON_0003837 thoracic segment connective tissue Dense connective tissue that separates the atria from the ventricles and provides physical support for the heart. http://purl.obolibrary.org/obo/GO_0061519 macrophage homeostasis http://purl.obolibrary.org/obo/GO_0002262 myeloid cell homeostasis The process of regulating the proliferation and elimination of macrophage cells such that the total number of myeloid cells within a whole or part of an organism is stable over time in the absence of an outside stimulus. http://purl.obolibrary.org/obo/UBERON_0004293 parasympathetic nerve http://purl.obolibrary.org/obo/UBERON_0001021 nerve A nerve that is part of a parasympathetic nervous system [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0061520 Langerhans cell differentiation http://purl.obolibrary.org/obo/GO_0043011 myeloid dendritic cell differentiation The process in which a precursor cell type acquires the specialized features of a Langerhans cell. http://purl.obolibrary.org/obo/UBERON_0004294 glomerular capillary endothelium http://purl.obolibrary.org/obo/UBERON_0004189 glomerular endothelium An endothelium that is part of a glomerular capillary. http://purl.obolibrary.org/obo/GO_0061521 hepatic stellate cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a hepatic stellate cell. http://purl.obolibrary.org/obo/GO_0061523 cilium disassembly http://purl.obolibrary.org/obo/GO_1903008 organelle disassembly A cellular process that results in the breakdown of a cilium. http://purl.obolibrary.org/obo/UBERON_0004295 sympathetic nerve trunk http://purl.obolibrary.org/obo/UBERON_0002464 nerve trunk A nerve trunk that is part of a sympathetic nervous system [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0061524 central canal development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the formation of the central canal of the spinal cord from its formation to the mature structure. The central canal is a spinal cord structure that is part of the ventricular system and is filled with cerebral-spinal fluid and runs the length of the spinal cord. http://purl.obolibrary.org/obo/UBERON_0004296 respiratory system lymphatic vessel smooth muscle http://purl.obolibrary.org/obo/UBERON_0004232 lymphatic vessel smooth muscle A lymphatic vessel smooth muscle that is part of a respiratory system [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0061527 dopamine secretion, neurotransmission http://purl.obolibrary.org/obo/GO_0099124 axonal dopamine secretion The regulated release of dopamine by a cell in which the dopamine acts as a neurotransmitter. http://purl.obolibrary.org/obo/UBERON_0004297 respiratory system blood vessel smooth muscle http://purl.obolibrary.org/obo/UBERON_0004237 blood vessel smooth muscle A blood vessel smooth muscle that is part of a respiratory system [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0061533 norepinephrine secretion, neurotransmission http://purl.obolibrary.org/obo/GO_0048243 norepinephrine secretion The regulated release of norepinephrine by a cell, in which the norepinephrine acts as a neurotransmitter. http://purl.obolibrary.org/obo/UBERON_0004300 distal phalanx http://purl.obolibrary.org/obo/UBERON_0003221 phalanx Distal-most phalanx within a digit. http://purl.obolibrary.org/obo/GO_0061534 gamma-aminobutyric acid secretion, neurotransmission http://purl.obolibrary.org/obo/GO_0014051 gamma-aminobutyric acid secretion The regulated release of gamma-aminobutyric acid by a cell, in which the gamma-aminobutyric acid acts as a neurotransmitter. http://purl.obolibrary.org/obo/UBERON_0004301 middle phalanx http://purl.obolibrary.org/obo/UBERON_0003221 phalanx A phalanx located between proximal and distal phalanges. http://purl.obolibrary.org/obo/GO_0061535 glutamate secretion, neurotransmission http://purl.obolibrary.org/obo/GO_0051938 L-glutamate import The controlled release of glutamate by a cell, in which the glutamate acts as a neurotransmitter. http://purl.obolibrary.org/obo/UBERON_0004302 proximal phalanx http://purl.obolibrary.org/obo/UBERON_0003221 phalanx Proximal-most phalanx within a digit. http://purl.obolibrary.org/obo/GO_0061536 glycine secretion http://purl.obolibrary.org/obo/GO_0015816 glycine transport The controlled release of glycine by a cell. http://purl.obolibrary.org/obo/UBERON_0004340 allantois http://purl.obolibrary.org/obo/UBERON_0005631 extraembryonic membrane A membranous sac that develops from the posterior part of the alimentary canal in the embryos of mammals, birds, and reptiles, and it is important in the formation of the umbilical cord and placenta in mammals[VHOG]. http://purl.obolibrary.org/obo/GO_0061537 glycine secretion, neurotransmission http://purl.obolibrary.org/obo/GO_0061536 glycine secretion The controlled release of glycine by a cell, in which glycine acts as a neurotransmitter. http://purl.obolibrary.org/obo/UBERON_0004341 primitive streak http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue The primitive streak is a structure that forms during the early stages of avian, reptilian and mammalian embryonic development[WP]. the midline ridge of the embryonic epiblast that later develops into mesoderm and endoderm[MP]. http://purl.obolibrary.org/obo/GO_0061538 histamine secretion, neurotransmission http://purl.obolibrary.org/obo/GO_0015807 L-amino acid transport The controlled release of histamine by a cell, in which the histamine acts as a neurotransmitter. http://purl.obolibrary.org/obo/UBERON_0004345 trophectoderm http://purl.obolibrary.org/obo/UBERON_0005292 extraembryonic tissue Outermost layer of cells in the blastodermic vesicle, which will develop into the trophoblast layer and then contact the endometrium and take part in establishing the embryo's means of nutrition. http://purl.obolibrary.org/obo/GO_0061544 peptide secretion, neurotransmission http://purl.obolibrary.org/obo/GO_0007269 neurotransmitter secretion The controlled release of a peptide from a cell in which the peptide acts as a neurotransmitter. http://purl.obolibrary.org/obo/UBERON_0004347 limb bud http://purl.obolibrary.org/obo/UBERON_0004357 paired limb/fin bud An outgrowth on the lateral trunk of the embryo that develops into a limb. The limb bud is divided into ectoderm and mesenchyme[cjm, modified from MP]. http://purl.obolibrary.org/obo/GO_0061548 ganglion development http://purl.obolibrary.org/obo/GO_0009888 tissue development The process whose specific outcome is the progression of a ganglion over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/UBERON_0004348 optic eminence http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure The embryonic structure that gives rise to the corneal ectoderm. http://purl.obolibrary.org/obo/GO_0061549 sympathetic ganglion development http://purl.obolibrary.org/obo/GO_0061548 ganglion development The process whose specific outcome is the progression of a sympathetic ganglion over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/UBERON_0004356 apical ectodermal ridge http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure Multilayered ectodermal region at the distal tip of a limb or fin bud necessary for the proper development of the underlying mesenchyme[MP,modified]. Along with the zone of polarizing activity, it is a crucial organizing region during limb development[WP]. http://purl.obolibrary.org/obo/GO_0061551 trigeminal ganglion development http://purl.obolibrary.org/obo/GO_0061550 cranial ganglion development The process whose specific outcome is the progression of a trigeminal ganglion over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/UBERON_0004357 paired limb/fin bud http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure An outgrowth on the lateral trunk of the embryo that develops into a limb or paired fin. The limb/fin bud is divided into ectoderm and mesenchyme[cjm, modified from MP]. http://purl.obolibrary.org/obo/GO_0061552 ganglion morphogenesis http://purl.obolibrary.org/obo/GO_0048729 tissue morphogenesis The process in which the anatomical structures of ganglion are generated and organized. http://purl.obolibrary.org/obo/GO_0061553 ganglion maturation http://purl.obolibrary.org/obo/GO_0071695 anatomical structure maturation A developmental process, independent of morphogenetic (shape) change, that is required for ganglion to attain its fully functional state. http://purl.obolibrary.org/obo/UBERON_0004362 pharyngeal arch 1 http://purl.obolibrary.org/obo/UBERON_0002539 pharyngeal arch The first of the series of pharyngeal arches that develop into jaw bones or their homologs, and their associated nerves and arteries. http://purl.obolibrary.org/obo/GO_0061554 ganglion formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process that gives rise to ganglion. This process pertains to the initial formation of a structure from unspecified parts. http://purl.obolibrary.org/obo/UBERON_0004364 ectoplacental cone http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure Thickened trophoblast of the blastocyst in rodents that becomes the fetal portion of the placenta. http://purl.obolibrary.org/obo/GO_0061556 trigeminal ganglion morphogenesis http://purl.obolibrary.org/obo/GO_0061559 cranial ganglion morphogenesis The process in which the anatomical structure of a trigeminal ganglion is generated and organized. http://purl.obolibrary.org/obo/UBERON_0004365 vitelline blood vessel http://purl.obolibrary.org/obo/UBERON_0001981 blood vessel Blood vessel that is connected to the yolk sac. http://purl.obolibrary.org/obo/GO_0061557 trigeminal ganglion maturation http://purl.obolibrary.org/obo/GO_0061558 cranial ganglion maturation A developmental process, independent of morphogenetic (shape) change, that is required for a trigeminal ganglion to attain its fully functional state. http://purl.obolibrary.org/obo/UBERON_0004367 Descemet's membrane http://purl.obolibrary.org/obo/UBERON_0005769 basement membrane of epithelium A transparent homogeneous acellular layer found between the substantia propria and the endothelial layer of the cornea[MP]. http://purl.obolibrary.org/obo/GO_0061558 cranial ganglion maturation http://purl.obolibrary.org/obo/GO_0061553 ganglion maturation A developmental process, independent of morphogenetic (shape) change, that is required for a cranial ganglion to attain its fully functional state. http://purl.obolibrary.org/obo/GO_0061559 cranial ganglion morphogenesis http://purl.obolibrary.org/obo/GO_0061552 ganglion morphogenesis The process in which the anatomical structure of a cranial ganglion is generated and organized. http://purl.obolibrary.org/obo/UBERON_0004370 anterior limiting lamina of cornea http://purl.obolibrary.org/obo/UBERON_0005769 basement membrane of epithelium A transparent homogeneous acellular layer, 6 to 9 um thick, lying between the basal lamina of the outer layer of stratified epithelium and the substantia propria of the cornea; it is considered to be a basement membrane. http://purl.obolibrary.org/obo/GO_0061560 cranial ganglion formation http://purl.obolibrary.org/obo/GO_0061554 ganglion formation The process that gives rise to a cranial ganglion. This process pertains to the initial formation of a structure from unspecified parts. http://purl.obolibrary.org/obo/UBERON_0004374 vitelline vasculature http://purl.obolibrary.org/obo/UBERON_0002049 vasculature Vascular network that is connected to the yolk sac. http://purl.obolibrary.org/obo/GO_0061561 trigeminal ganglion formation http://purl.obolibrary.org/obo/GO_0061560 cranial ganglion formation The process that gives rise to the trigeminal ganglion. This process pertains to the initial formation of a structure from unspecified parts. http://purl.obolibrary.org/obo/GO_0061580 colon epithelial cell migration http://purl.obolibrary.org/obo/GO_0061582 intestinal epithelial cell migration The orderly movement of a colonic epithelial cell from one site to another, often during the development of a multicellular organism. http://purl.obolibrary.org/obo/UBERON_0004375 bone of free limb or fin http://purl.obolibrary.org/obo/UBERON_0010740 bone of appendage girdle complex A bone that is part of an appendage [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0061581 corneal epithelial cell migration http://purl.obolibrary.org/obo/GO_0010631 epithelial cell migration The orderly movement of a corneal epithelial cell from one site to another, often during the development of a multicellular organism. http://purl.obolibrary.org/obo/UBERON_0004378 proximal metaphysis http://purl.obolibrary.org/obo/UBERON_0001438 metaphysis A metaphysis that is in the proximal side of a diaphysis. http://purl.obolibrary.org/obo/GO_0061582 intestinal epithelial cell migration http://purl.obolibrary.org/obo/GO_0010631 epithelial cell migration The orderly movement of an intestinal epithelial cell from one site to another, often during the development of a multicellular organism. http://purl.obolibrary.org/obo/UBERON_0004380 proximal epiphysis http://purl.obolibrary.org/obo/UBERON_0001437 epiphysis An epiphysis that is on the proximal side of the bone. http://purl.obolibrary.org/obo/GO_0061584 orexin secretion http://purl.obolibrary.org/obo/GO_0002790 peptide secretion The controlled release of orexin from a cell or a tissue. http://purl.obolibrary.org/obo/GO_0061585 orexin secretion, neurotransmission http://purl.obolibrary.org/obo/GO_0061584 orexin secretion The controlled release of orexin from a cell in which orexin acts as a neurotransmitter. http://purl.obolibrary.org/obo/GO_0061626 pharyngeal arch artery morphogenesis http://purl.obolibrary.org/obo/GO_0048844 artery morphogenesis The process in which the anatomical structures of a pharyngeal arch artery is generated and organized. The pharyngeal arch arteries are a series of six paired embryological vascular structures, the development of which give rise to several major arteries, such as the stapedial artery, the middle meningeal artery, the internal carotid artery and the pulmonary artery. http://purl.obolibrary.org/obo/UBERON_0004381 skeleton of limb http://purl.obolibrary.org/obo/UBERON_0011582 paired limb/fin skeleton The collection of all skeletal elements in an individual limb. http://purl.obolibrary.org/obo/GO_0061629 RNA polymerase II-specific DNA-binding transcription factor binding http://purl.obolibrary.org/obo/GO_0140297 DNA-binding transcription factor binding Binding to a sequence-specific DNA binding RNA polymerase II transcription factor, any of the factors that interact selectively and non-covalently with a specific DNA sequence in order to modulate transcription. http://purl.obolibrary.org/obo/GO_0061668 mitochondrial ribosome assembly http://purl.obolibrary.org/obo/GO_0042255 ribosome assembly The aggregation, arrangement and bonding together of the mitochondrial ribosome and of its subunits. http://purl.obolibrary.org/obo/GO_0061682 seminal vesicle morphogenesis http://purl.obolibrary.org/obo/GO_0022612 gland morphogenesis The process in which the anatomical structures of a seminal vesicle are generated and organized. http://purl.obolibrary.org/obo/GO_0061725 cytosolic lipolysis http://purl.obolibrary.org/obo/GO_0016042 lipid catabolic process The chemical reactions and pathways resulting in the breakdown of lipid droplets and hydrolysis of stored triglycerides occurring through the orchestrated activation of cytosolic lipases. http://purl.obolibrary.org/obo/UBERON_0004382 epiphysis of humerus http://purl.obolibrary.org/obo/UBERON_0001437 epiphysis An epiphysis that is part of a humerus [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0061792 secretory granule maturation http://purl.obolibrary.org/obo/GO_0071695 anatomical structure maturation Steps required to transform an immature secretory vesicle into a mature secretory vesicle. Typically proceeds through homotypic membrane fusion and membrane remodeling. http://purl.obolibrary.org/obo/UBERON_0004383 epiphysis of tibia http://purl.obolibrary.org/obo/UBERON_0001437 epiphysis An epiphysis that is part of a tibia [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0061847 response to cholecystokinin http://purl.obolibrary.org/obo/GO_0043434 response to peptide hormone Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cholecystokinin stimulus. http://purl.obolibrary.org/obo/GO_0061848 cellular response to cholecystokinin http://purl.obolibrary.org/obo/GO_0061847 response to cholecystokinin Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cholecystokinin stimulus. http://purl.obolibrary.org/obo/GO_0070050 neuron cellular homeostasis http://purl.obolibrary.org/obo/GO_0019725 cellular homeostasis The cellular homeostatic process that preserves a neuron in a stable, differentiated functional and structural state. http://purl.obolibrary.org/obo/UBERON_0004384 epiphysis of femur http://purl.obolibrary.org/obo/UBERON_0001437 epiphysis An epiphysis that is part of a femur [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0070051 fibrinogen binding http://purl.obolibrary.org/obo/GO_0044877 protein-containing complex binding Binding to fibrinogen, a highly soluble hexameric glycoprotein complex that is found in blood plasma and is converted to fibrin by thrombin in the coagulation cascade. http://purl.obolibrary.org/obo/UBERON_0004387 epiphysis of phalanx of manus http://purl.obolibrary.org/obo/UBERON_0004446 epiphysis of phalanx An epiphysis that is part of a phalanx of a manus [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0070062 extracellular exosome http://purl.obolibrary.org/obo/GO_1903561 extracellular vesicle A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm. http://purl.obolibrary.org/obo/UBERON_0004388 epiphysis of fibula http://purl.obolibrary.org/obo/UBERON_0001437 epiphysis An epiphysis that is part of a fibula [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0070091 glucagon secretion http://purl.obolibrary.org/obo/GO_0030072 peptide hormone secretion The regulated release of glucagon from secretory granules in the A (alpha) cells of the pancreas (islets of Langerhans). http://purl.obolibrary.org/obo/UBERON_0004389 epiphysis of metatarsal bone http://purl.obolibrary.org/obo/UBERON_0011973 epiphysis of phalanx of pes An epiphysis that is part of a metatarsal bone [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0070092 regulation of glucagon secretion http://purl.obolibrary.org/obo/GO_0090276 regulation of peptide hormone secretion Any process that modulates the frequency, rate or extent of the regulated release of glucagon. http://purl.obolibrary.org/obo/UBERON_0004390 epiphysis of metacarpal bone http://purl.obolibrary.org/obo/UBERON_0001437 epiphysis An epiphysis that is part of a metacarpal bone [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0070093 negative regulation of glucagon secretion http://purl.obolibrary.org/obo/GO_0070092 regulation of glucagon secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of glucagon. http://purl.obolibrary.org/obo/UBERON_0004400 bone tissue of epiphysis http://purl.obolibrary.org/obo/UBERON_0005808 bone tissue of long bone A portion of bone tissue that is part of a epiphysis [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0070094 positive regulation of glucagon secretion http://purl.obolibrary.org/obo/GO_0070092 regulation of glucagon secretion Any process that activates or increases the frequency, rate or extent of the regulated release of glucagon. http://purl.obolibrary.org/obo/UBERON_0004402 bone tissue of proximal epiphysis http://purl.obolibrary.org/obo/UBERON_0004400 bone tissue of epiphysis A portion of bone tissue that is part of a proximal epiphysis [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0070124 mitochondrial translational initiation http://purl.obolibrary.org/obo/GO_0006413 translational initiation The process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion. This includes the formation of a complex of the ribosome, mRNA, and an initiation complex that contains the first aminoacyl-tRNA. http://purl.obolibrary.org/obo/UBERON_0004403 periosteum of epiphysis http://purl.obolibrary.org/obo/UBERON_0016896 periosteum of long bone A periosteum that is part of a epiphysis [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0070125 mitochondrial translational elongation http://purl.obolibrary.org/obo/GO_0006414 translational elongation The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis in a mitochondrion. http://purl.obolibrary.org/obo/UBERON_0004411 proximal epiphysis of humerus http://purl.obolibrary.org/obo/UBERON_0004382 epiphysis of humerus The upper extremity of the humerus (proximal humerus) consists of a large rounded head joined to the body by a constricted portion called the neck, and two eminences, the greater and lesser tubercles. http://purl.obolibrary.org/obo/GO_0070126 mitochondrial translational termination http://purl.obolibrary.org/obo/GO_0006415 translational termination The process resulting in the release of a polypeptide chain from the ribosome in a mitochondrion, usually in response to a termination codon (note that mitochondria use variants of the universal genetic code that differ between different taxa). http://purl.obolibrary.org/obo/UBERON_0004412 proximal epiphysis of femur http://purl.obolibrary.org/obo/UBERON_0004384 epiphysis of femur A proximal epiphysis that is part of a femur [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0070129 regulation of mitochondrial translation http://purl.obolibrary.org/obo/GO_0006417 regulation of translation Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion. http://purl.obolibrary.org/obo/UBERON_0004414 proximal epiphysis of phalanx of manus http://purl.obolibrary.org/obo/UBERON_0004447 proximal epiphysis of phalanx A proximal epiphysis that is part of a phalanx of manus [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0070130 negative regulation of mitochondrial translation http://purl.obolibrary.org/obo/GO_0070129 regulation of mitochondrial translation Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion. http://purl.obolibrary.org/obo/UBERON_0004415 proximal epiphysis of metatarsal bone http://purl.obolibrary.org/obo/UBERON_0004389 epiphysis of metatarsal bone A proximal epiphysis that is part of a metatarsal bone [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0070132 regulation of mitochondrial translational initiation http://purl.obolibrary.org/obo/GO_0070129 regulation of mitochondrial translation Any process that modulates the frequency, rate or extent of the process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion. http://purl.obolibrary.org/obo/UBERON_0004416 proximal epiphysis of metacarpal bone http://purl.obolibrary.org/obo/UBERON_0004390 epiphysis of metacarpal bone A proximal epiphysis that is part of a metacarpal bone [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0070133 negative regulation of mitochondrial translational initiation http://purl.obolibrary.org/obo/GO_0070132 regulation of mitochondrial translational initiation Any process that stops, prevents, or reduces the frequency, rate or extent of the process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion. http://purl.obolibrary.org/obo/GO_0070134 positive regulation of mitochondrial translational initiation http://purl.obolibrary.org/obo/GO_0070132 regulation of mitochondrial translational initiation Any process that activates or increases the frequency, rate or extent of the process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion. http://purl.obolibrary.org/obo/GO_0070170 regulation of tooth mineralization http://purl.obolibrary.org/obo/GO_0070167 regulation of biomineral tissue development Any process that modulates the frequency, rate or extent of tooth mineralization, the deposition of calcium salts in tooth structures. http://purl.obolibrary.org/obo/GO_0070171 negative regulation of tooth mineralization http://purl.obolibrary.org/obo/GO_0070170 regulation of tooth mineralization Any process that stops, prevents, or reduces the frequency, rate or extent of tooth mineralization, the deposition of calcium salts in tooth structures. http://purl.obolibrary.org/obo/UBERON_0004446 epiphysis of phalanx http://purl.obolibrary.org/obo/UBERON_0001437 epiphysis An epiphysis that is part of a phalanx [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004447 proximal epiphysis of phalanx http://purl.obolibrary.org/obo/UBERON_0004446 epiphysis of phalanx A proximal epiphysis that is part of a phalanx [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0070172 positive regulation of tooth mineralization http://purl.obolibrary.org/obo/GO_0070170 regulation of tooth mineralization Any process that activates or increases the frequency, rate or extent of tooth mineralization, the deposition of calcium salts in tooth structures. http://purl.obolibrary.org/obo/UBERON_0004449 cerebral artery http://purl.obolibrary.org/obo/UBERON_0004573 systemic artery One of three main pairs of arteries and their branches, which irrigate the cerebrum of the brain. http://purl.obolibrary.org/obo/UBERON_0004451 trunk or cervical vertebra http://purl.obolibrary.org/obo/UBERON_0004247 bone of dorsum A vertebra in the trunk or cervical region. Includes all cervical, thoracic and lumbar vertebrae, but excludes caudal vertebra. http://purl.obolibrary.org/obo/GO_0070199 establishment of protein localization to chromosome http://purl.obolibrary.org/obo/GO_0072594 establishment of protein localization to organelle The directed movement of a protein to a specific location on a chromosome. http://purl.obolibrary.org/obo/UBERON_0004452 carpal region http://purl.obolibrary.org/obo/UBERON_0008785 upper limb segment A mesopodium that is part of a manus. Includes as parts the carpal skeleton and associated tissues[cjm]. The anatomical region surrounding the carpus including the distal parts of the bones of the forearm and the proximal parts of the metacarpus or five metacarpal bones and the series of joints between these bones, thus referred to as wrist joints. This region also includes the carpal tunnel, the anatomical snuff box, the flexor retinaculum, and the extensor retinaculum[WP,unvetted]. http://purl.obolibrary.org/obo/UBERON_0004453 metacarpus region http://purl.obolibrary.org/obo/UBERON_0009877 metapodium region A metapodium region that is part of a manus. http://purl.obolibrary.org/obo/GO_0070202 regulation of establishment of protein localization to chromosome http://purl.obolibrary.org/obo/GO_0070201 regulation of establishment of protein localization Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location on a chromosome. http://purl.obolibrary.org/obo/UBERON_0004454 tarsal region http://purl.obolibrary.org/obo/UBERON_0008784 lower limb segment Mesopodial segment of the pes, including the tarsal skeleton and associated tissues. http://purl.obolibrary.org/obo/UBERON_0004455 neurula embryo http://purl.obolibrary.org/obo/UBERON_0000922 embryo An embryo at the neurula stage. http://purl.obolibrary.org/obo/GO_0070232 regulation of T cell apoptotic process http://purl.obolibrary.org/obo/GO_0070228 regulation of lymphocyte apoptotic process Any process that modulates the occurrence or rate of T cell death by apoptotic process. http://purl.obolibrary.org/obo/UBERON_0004456 entire sense organ system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system Sum of all sensory systems in an organism. http://purl.obolibrary.org/obo/UBERON_0004461 skeletal musculature of head http://purl.obolibrary.org/obo/UBERON_0008229 craniocervical region musculature Any collection of skeletal muscles that is part of a head [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0070233 negative regulation of T cell apoptotic process http://purl.obolibrary.org/obo/GO_0070232 regulation of T cell apoptotic process Any process that stops, prevents, or reduces the frequency, rate or extent of T cell death by apoptotic process. http://purl.obolibrary.org/obo/UBERON_0004462 musculature of body wall http://purl.obolibrary.org/obo/UBERON_0001015 musculature Any collection of muscles that is part of a body wall [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004463 musculature of hindlimb stylopod http://purl.obolibrary.org/obo/UBERON_0004466 musculature of leg Any collection of muscles that is part of a hindlimb stylopod (upper leg / thigh)[Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0070234 positive regulation of T cell apoptotic process http://purl.obolibrary.org/obo/GO_0070232 regulation of T cell apoptotic process Any process that activates or increases the frequency, rate or extent of T cell death by apoptotic process. http://purl.obolibrary.org/obo/UBERON_0004464 musculature of thorax http://purl.obolibrary.org/obo/UBERON_0004479 musculature of trunk Any collection of muscles that is part of a thorax [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004465 musculature of neck http://purl.obolibrary.org/obo/UBERON_0001015 musculature Any collection of muscles that is part of a neck [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0070242 thymocyte apoptotic process http://purl.obolibrary.org/obo/GO_0070231 T cell apoptotic process Any apoptotic process in a thymocyte, an immature T cell located in the thymus. http://purl.obolibrary.org/obo/UBERON_0004466 musculature of leg http://purl.obolibrary.org/obo/UBERON_0004482 musculature of lower limb Any collection of muscles that is part of a lower leg or upper leg [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004467 musculature of pharynx http://purl.obolibrary.org/obo/UBERON_0001015 musculature The collection of muscles that acts on the pharynx. http://purl.obolibrary.org/obo/GO_0070243 regulation of thymocyte apoptotic process http://purl.obolibrary.org/obo/GO_0070232 regulation of T cell apoptotic process Any process that modulates the occurrence or rate of thymocyte death by apoptotic process. http://purl.obolibrary.org/obo/UBERON_0004469 musculature of back http://purl.obolibrary.org/obo/UBERON_0001015 musculature Any collection of muscles that is part of a back [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004470 musculature of pelvic girdle http://purl.obolibrary.org/obo/UBERON_0014792 musculature of pelvic complex Any collection of muscles that is part of a pelvic girdle [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0070244 negative regulation of thymocyte apoptotic process http://purl.obolibrary.org/obo/GO_0070243 regulation of thymocyte apoptotic process Any process that stops, prevents, or reduces the frequency, rate or extent of thymocyte death by apoptotic process. http://purl.obolibrary.org/obo/UBERON_0004471 musculature of pectoral girdle http://purl.obolibrary.org/obo/UBERON_0014793 musculature of pectoral complex A subdivision of the musculature of the body in the pectoral girdle region. Includes pectoral and shoulder muscles. http://purl.obolibrary.org/obo/UBERON_0004473 musculature of face http://purl.obolibrary.org/obo/UBERON_0008229 craniocervical region musculature Any collection of muscles that is part of a face. http://purl.obolibrary.org/obo/GO_0070245 positive regulation of thymocyte apoptotic process http://purl.obolibrary.org/obo/GO_0070243 regulation of thymocyte apoptotic process Any process that activates or increases the frequency, rate or extent of thymocyte death by apoptotic process. http://purl.obolibrary.org/obo/UBERON_0004474 musculature of arm http://purl.obolibrary.org/obo/UBERON_0004481 musculature of upper limb Any collection of muscles that is part of an arm [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004475 musculature of hip http://purl.obolibrary.org/obo/UBERON_0001015 musculature The collection of muscles that form attachments to the hip skeleton. http://purl.obolibrary.org/obo/GO_0070246 natural killer cell apoptotic process http://purl.obolibrary.org/obo/GO_0070227 lymphocyte apoptotic process Any apoptotic process in a natural killer cell, a lymphocyte that can spontaneously kill a variety of target cells without prior antigenic activation. http://purl.obolibrary.org/obo/UBERON_0004476 musculature of shoulder http://purl.obolibrary.org/obo/UBERON_0001015 musculature The collection of muscles that form attachments to the shoulder skeleton. http://purl.obolibrary.org/obo/UBERON_0004478 musculature of larynx http://purl.obolibrary.org/obo/UBERON_0001015 musculature The collection of muscles that are part of the larynx. http://purl.obolibrary.org/obo/UBERON_0004479 musculature of trunk http://purl.obolibrary.org/obo/UBERON_0001015 musculature Any collection of muscles that is part of a trunk [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0070247 regulation of natural killer cell apoptotic process http://purl.obolibrary.org/obo/GO_0070228 regulation of lymphocyte apoptotic process Any process that modulates the occurrence or rate of natural killer cell death by apoptotic process. http://purl.obolibrary.org/obo/UBERON_0004480 musculature of limb http://purl.obolibrary.org/obo/UBERON_0007271 appendage musculature Any collection of muscles that is part of a limb [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004481 musculature of upper limb http://purl.obolibrary.org/obo/UBERON_0007269 pectoral appendage musculature Any collection of muscles that is part of a forelimb [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0070248 negative regulation of natural killer cell apoptotic process http://purl.obolibrary.org/obo/GO_0070247 regulation of natural killer cell apoptotic process Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell death by apoptotic process. http://purl.obolibrary.org/obo/UBERON_0004482 musculature of lower limb http://purl.obolibrary.org/obo/UBERON_0007270 pelvic appendage musculature Any collection of muscles that is part of a hindlimb [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004487 musculature of forelimb zeugopod http://purl.obolibrary.org/obo/UBERON_0004474 musculature of arm Any collection of muscles that is part of a lower arm [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0070249 positive regulation of natural killer cell apoptotic process http://purl.obolibrary.org/obo/GO_0070247 regulation of natural killer cell apoptotic process Any process that activates or increases the frequency, rate or extent of natural killer cell death by apoptotic process. http://purl.obolibrary.org/obo/UBERON_0004488 musculature of pes http://purl.obolibrary.org/obo/UBERON_0004482 musculature of lower limb Any collection of muscles that is part of a foot [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004489 musculature of manus http://purl.obolibrary.org/obo/UBERON_0004481 musculature of upper limb Any collection of muscles that is part of a manus [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004490 cardiac muscle tissue of atrium http://purl.obolibrary.org/obo/UBERON_0004493 cardiac muscle tissue of myocardium A portion of cardiac muscle tissue that is part of an atrium [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0070253 somatostatin secretion http://purl.obolibrary.org/obo/GO_0030072 peptide hormone secretion The regulated release of somatostatin from secretory granules in the D cells of the pancreas. http://purl.obolibrary.org/obo/UBERON_0004491 cardiac muscle tissue of interatrial septum http://purl.obolibrary.org/obo/UBERON_0004492 cardiac muscle tissue of cardiac septum A portion of cardiac muscle tissue that is part of a interatrial septum [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0070254 mucus secretion http://purl.obolibrary.org/obo/GO_0032941 secretion by tissue The regulated release of mucus by the mucosa. Mucus is a viscous slimy secretion consisting of mucins and various inorganic salts dissolved in water, with suspended epithelial cells and leukocytes. The mucosa, or mucous membrane, is the membrane covered with epithelium that lines the tubular organs of the body. Mucins are carbohydrate-rich glycoproteins that have a lubricating and protective function. http://purl.obolibrary.org/obo/UBERON_0004492 cardiac muscle tissue of cardiac septum http://purl.obolibrary.org/obo/UBERON_0001133 cardiac muscle tissue A portion of cardiac muscle tissue that is part of a cardiac septum [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0070255 regulation of mucus secretion http://purl.obolibrary.org/obo/GO_0051239 regulation of multicellular organismal process Any process that modulates the frequency, rate or extent of the regulated release of mucus from a cell or a tissue. http://purl.obolibrary.org/obo/UBERON_0004493 cardiac muscle tissue of myocardium http://purl.obolibrary.org/obo/UBERON_0001133 cardiac muscle tissue A portion of cardiac muscle tissue that is part of a myocardium [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0070256 negative regulation of mucus secretion http://purl.obolibrary.org/obo/GO_0070255 regulation of mucus secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of mucus from a cell or a tissue. http://purl.obolibrary.org/obo/UBERON_0004495 skeletal muscle tissue of diaphragm http://purl.obolibrary.org/obo/UBERON_0004830 respiratory system skeletal muscle A portion of skeletal muscle tissue that is part of a diaphragm [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0070257 positive regulation of mucus secretion http://purl.obolibrary.org/obo/GO_0070255 regulation of mucus secretion Any process that activates or increases the frequency, rate or extent of the regulated release of mucus from a cell or a tissue. http://purl.obolibrary.org/obo/UBERON_0004500 skeletal muscle tissue of deltoid http://purl.obolibrary.org/obo/UBERON_0001134 skeletal muscle tissue A portion of skeletal muscle tissue that is part of a deltoid [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0070285 pigment cell development http://purl.obolibrary.org/obo/GO_0048468 cell development The process whose specific outcome is the progression of a pigment cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a pigment cell fate. http://purl.obolibrary.org/obo/UBERON_0004509 skeletal muscle tissue of trapezius http://purl.obolibrary.org/obo/UBERON_0001134 skeletal muscle tissue A portion of skeletal muscle tissue that is part of a trapezius [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0070306 lens fiber cell differentiation http://purl.obolibrary.org/obo/GO_0030855 epithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a lens fiber cell, any of the elongated, tightly packed cells that make up the bulk of the mature lens in the camera-type eye. The cytoplasm of a lens fiber cell is devoid of most intracellular organelles including the cell nucleus, and contains primarily crystallins, a group of water-soluble proteins expressed in vary large quantities. http://purl.obolibrary.org/obo/UBERON_0004510 skeletal muscle tissue of pectoralis major http://purl.obolibrary.org/obo/UBERON_0003898 skeletal muscle tissue of trunk A portion of skeletal muscle tissue that is part of a pectoralis major [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004515 smooth muscle tissue of bronchiole http://purl.obolibrary.org/obo/UBERON_0004233 lower respiratory tract smooth muscle A portion of smooth muscle tissue that is part of a bronchiole [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0070307 lens fiber cell development http://purl.obolibrary.org/obo/GO_0002064 epithelial cell development The process whose specific outcome is the progression of a lens fiber cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a lens fiber cell fate. A lens fiber cell is any of the elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye. http://purl.obolibrary.org/obo/UBERON_0004516 smooth muscle tissue of terminal bronchiole http://purl.obolibrary.org/obo/UBERON_0004515 smooth muscle tissue of bronchiole A portion of smooth muscle tissue that is part of a terminal bronchiole [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0070341 fat cell proliferation http://purl.obolibrary.org/obo/GO_0008283 cell population proliferation The multiplication or reproduction of fat cells by cell division, resulting in the expansion of their population. A fat cell is an animal connective tissue cell specialized for the synthesis and storage of fat. http://purl.obolibrary.org/obo/UBERON_0004517 smooth muscle tissue of respiratory bronchiole http://purl.obolibrary.org/obo/UBERON_0004515 smooth muscle tissue of bronchiole A portion of smooth muscle tissue that is part of a respiratory bronchiole [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0070342 brown fat cell proliferation http://purl.obolibrary.org/obo/GO_0070341 fat cell proliferation The multiplication or reproduction of brown fat cells by cell division, resulting in the expansion of their population. A brown fat cell is a fat cell found the thermogenic form of adipose tissue found in newborns of many species. http://purl.obolibrary.org/obo/UBERON_0004518 muscle of vertebral column http://purl.obolibrary.org/obo/UBERON_0014892 skeletal muscle organ, vertebrate A muscle that is attached to a vertebra of the vertebral column. http://purl.obolibrary.org/obo/UBERON_0004520 striated muscle tissue of prostate http://purl.obolibrary.org/obo/UBERON_0008715 muscle tissue of prostate A portion of striated muscle tissue that is part of a prostate gland [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0070343 white fat cell proliferation http://purl.obolibrary.org/obo/GO_0070341 fat cell proliferation The multiplication or reproduction of white fat cells by cell division, resulting in the expansion of their population. http://purl.obolibrary.org/obo/UBERON_0004521 vasculature of muscle organ http://purl.obolibrary.org/obo/UBERON_0006876 vasculature of organ A vasculature that is part of a muscle organ [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0070344 regulation of fat cell proliferation http://purl.obolibrary.org/obo/GO_0042127 regulation of cell population proliferation Any process that modulates the frequency, rate or extent of fat cell proliferation. http://purl.obolibrary.org/obo/UBERON_0004522 vasculature of musculoskeletal system http://purl.obolibrary.org/obo/UBERON_0002049 vasculature A vasculature that is part of a musculoskeletal system [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0070345 negative regulation of fat cell proliferation http://purl.obolibrary.org/obo/GO_0070344 regulation of fat cell proliferation Any process that stops or decreases the rate or extent of fat cell proliferation. http://purl.obolibrary.org/obo/UBERON_0004525 cardiac muscle tissue of trabecula carnea of right ventricle http://purl.obolibrary.org/obo/UBERON_0003452 trabecula carnea cardiac muscle tissue A portion of trabecula carnea cardiac muscle tissue that is part of a right ventricle [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0070346 positive regulation of fat cell proliferation http://purl.obolibrary.org/obo/GO_0070344 regulation of fat cell proliferation Any process that activates or increases the rate or extent of fat cell proliferation. http://purl.obolibrary.org/obo/UBERON_0004526 cardiac muscle tissue of trabecula carnea of left ventricle http://purl.obolibrary.org/obo/UBERON_0003452 trabecula carnea cardiac muscle tissue A portion of trabecula carnea cardiac muscle tissue that is part of a left ventricle [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0070347 regulation of brown fat cell proliferation http://purl.obolibrary.org/obo/GO_0070344 regulation of fat cell proliferation Any process that modulates the frequency, rate or extent of brown fat cell proliferation. http://purl.obolibrary.org/obo/UBERON_0004529 anatomical projection http://purl.obolibrary.org/obo/UBERON_0034768 morphological feature A projection or outgrowth of tissue from a larger body or organ. http://purl.obolibrary.org/obo/GO_0070348 negative regulation of brown fat cell proliferation http://purl.obolibrary.org/obo/GO_0070347 regulation of brown fat cell proliferation Any process that stops or decreases the rate or extent of brown fat cell proliferation. http://purl.obolibrary.org/obo/UBERON_0004530 bony projection http://purl.obolibrary.org/obo/UBERON_4100000 skeletal element projection Anatomical projection that is composed of bone tissue. http://purl.obolibrary.org/obo/GO_0070349 positive regulation of brown fat cell proliferation http://purl.obolibrary.org/obo/GO_0070347 regulation of brown fat cell proliferation Any process that activates or increases the rate or extent of brown fat cell proliferation. http://purl.obolibrary.org/obo/UBERON_0004533 left testis http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure A testis that is in the left side of the genitalia [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0070350 regulation of white fat cell proliferation http://purl.obolibrary.org/obo/GO_0070344 regulation of fat cell proliferation Any process that modulates the frequency, rate or extent of white fat cell proliferation. http://purl.obolibrary.org/obo/UBERON_0004534 right testis http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure A testis that is in the right side of the genitalia [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0070351 negative regulation of white fat cell proliferation http://purl.obolibrary.org/obo/GO_0070350 regulation of white fat cell proliferation Any process that stops or decreases the rate or extent of white fat cell proliferation. http://purl.obolibrary.org/obo/UBERON_0004536 lymph vasculature http://purl.obolibrary.org/obo/UBERON_0002049 vasculature A network of blunt ended vessels lacking direct connection to the blood vascular system. These vessels collect and drain fluids and macromolecules from interstitial spaces throughout the animal. They derive from a subpopulation of endothelial cells and have walls that are much thinner than the blood carrying vessels. Lymphatic vessels are usually classified as either superficial or deep. http://purl.obolibrary.org/obo/GO_0070352 positive regulation of white fat cell proliferation http://purl.obolibrary.org/obo/GO_0070350 regulation of white fat cell proliferation Any process that activates or increases the rate or extent of white fat cell proliferation. http://purl.obolibrary.org/obo/UBERON_0004537 blood vasculature http://purl.obolibrary.org/obo/UBERON_0002049 vasculature A vascular network consisting of blood vessels. http://purl.obolibrary.org/obo/GO_0070365 hepatocyte differentiation http://purl.obolibrary.org/obo/GO_0030855 epithelial cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a hepatocyte. A hepatocyte is specialized epithelial cell that is organized into interconnected plates called lobules, and is the main structural component of the liver. http://purl.obolibrary.org/obo/UBERON_0004538 left kidney http://purl.obolibrary.org/obo/UBERON_0002113 kidney A kidney that is part of a left side of organism [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0070366 regulation of hepatocyte differentiation http://purl.obolibrary.org/obo/GO_0030856 regulation of epithelial cell differentiation Any process that modulates the frequency, rate or extent of hepatocyte differentiation. http://purl.obolibrary.org/obo/UBERON_0004539 right kidney http://purl.obolibrary.org/obo/UBERON_0002113 kidney A kidney that is part of a right side of organism [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0070367 negative regulation of hepatocyte differentiation http://purl.obolibrary.org/obo/GO_0070366 regulation of hepatocyte differentiation Any process that stops or decreases the rate or extent of hepatocyte differentiation. http://purl.obolibrary.org/obo/UBERON_0004544 epididymis epithelium http://purl.obolibrary.org/obo/UBERON_0034969 epithelial layer of duct The layer of secretory cells which lines the epididymis. http://purl.obolibrary.org/obo/GO_0070368 positive regulation of hepatocyte differentiation http://purl.obolibrary.org/obo/GO_0070366 regulation of hepatocyte differentiation Any process that activates or increases the rate or extent of hepatocyte differentiation. http://purl.obolibrary.org/obo/UBERON_0004545 external capsule of telencephalon http://purl.obolibrary.org/obo/UBERON_0002437 cerebral hemisphere white matter Any of the series of white matter fiber tracts in the brain that run between the most lateral segment of the lentiform nucleus and the claustrum; the white matter of the external capsule contains fibers known as corticocortical association fibers which are responsible for connecting the cerebral cortex to another cortical area; the capsule appears as a thin white sheet of white matter and provides a route for cholinergic fibers from the basal forebrain to the cerebral cortex; it eventually joins the internal capsule around the lentiform nucleus. http://purl.obolibrary.org/obo/GO_0070444 oligodendrocyte progenitor proliferation http://purl.obolibrary.org/obo/GO_0061351 neural precursor cell proliferation The multiplication or reproduction of oligodendrocyte progenitor cells by cell division, resulting in the expansion of their population. Oligodendrocyte progenitors give rise to oligodendrocytes, which form the insulating myelin sheath of axons in the central nervous system. http://purl.obolibrary.org/obo/UBERON_0004548 left eye http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure An eye that is part of a left side of organism [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004549 right eye http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure An eye that is part of a right side of organism [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0070445 regulation of oligodendrocyte progenitor proliferation http://purl.obolibrary.org/obo/GO_2000177 regulation of neural precursor cell proliferation Any process that modulates the frequency, rate or extent of oligodendrocyte progenitor proliferation. http://purl.obolibrary.org/obo/UBERON_0004550 gastroesophageal sphincter http://purl.obolibrary.org/obo/UBERON_0011185 gastrointestinal sphincter The thick circular layer of smooth gastric musculature encircling the gastroesophageal junction that functions to reduce backflow into the esophagus from the stomach. http://purl.obolibrary.org/obo/UBERON_0004552 digital artery http://purl.obolibrary.org/obo/UBERON_0003514 limb blood vessel An artery that is part of a digit [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0070446 negative regulation of oligodendrocyte progenitor proliferation http://purl.obolibrary.org/obo/GO_0070445 regulation of oligodendrocyte progenitor proliferation Any process that stops or decreases the rate or extent of oligodendrocyte progenitor proliferation. http://purl.obolibrary.org/obo/UBERON_0004553 forelimb digital artery http://purl.obolibrary.org/obo/UBERON_0004552 digital artery A digital artery that is part of a forelimb [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0070447 positive regulation of oligodendrocyte progenitor proliferation http://purl.obolibrary.org/obo/GO_0070445 regulation of oligodendrocyte progenitor proliferation Any process that activates or increases the rate or extent of oligodendrocyte progenitor proliferation. http://purl.obolibrary.org/obo/UBERON_0004554 hindlimb digital artery http://purl.obolibrary.org/obo/UBERON_0004552 digital artery A digital artery that is part of a hindlimb [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0070451 cell hair http://purl.obolibrary.org/obo/GO_0120025 plasma membrane bounded cell projection A long, thin cell projection that contains F-actin and tubulin, with microtubules centrally located and F-actin peripherally located. http://purl.obolibrary.org/obo/UBERON_0004571 systemic arterial system http://purl.obolibrary.org/obo/UBERON_0007798 vascular system The part of the arterial system which carries oxygenated blood away from the heart to the body, and returns deoxygenated blood back to the heart. http://purl.obolibrary.org/obo/GO_0070459 prolactin secretion http://purl.obolibrary.org/obo/GO_0030072 peptide hormone secretion The regulated release of prolactin, a peptide hormone that stimulates lactation, from secretory granules in the anterior pituitary. http://purl.obolibrary.org/obo/UBERON_0004572 arterial system http://purl.obolibrary.org/obo/UBERON_0007798 vascular system The part of the cardiovascular system consisting of all arteries. http://purl.obolibrary.org/obo/GO_0070460 thyroid-stimulating hormone secretion http://purl.obolibrary.org/obo/GO_0030072 peptide hormone secretion The regulated release of thyroid-stimulating hormone, a peptide hormone that stimulates the activity of the thyroid gland, from secretory granules in the anterior pituitary. http://purl.obolibrary.org/obo/GO_0070560 protein secretion by platelet http://purl.obolibrary.org/obo/GO_0140029 exocytic process The regulated release of proteins by a platelet or group of platelets. http://purl.obolibrary.org/obo/UBERON_0004573 systemic artery http://purl.obolibrary.org/obo/UBERON_0001637 artery An artery of the systemic circulation, which is the part of the cardiovascular system which carries oxygenated blood away from the heart, to the body, and returns deoxygenated blood back to the heart. http://purl.obolibrary.org/obo/GO_0070634 transepithelial ammonium transport http://purl.obolibrary.org/obo/GO_0070633 transepithelial transport The directed movement of ammonium ions from one side of an epithelium to the other. http://purl.obolibrary.org/obo/UBERON_0004581 systemic venous system http://purl.obolibrary.org/obo/UBERON_0002049 vasculature The part of the venous system that drains the general body tissues[Kardong]. http://purl.obolibrary.org/obo/GO_0070662 mast cell proliferation http://purl.obolibrary.org/obo/GO_0070661 leukocyte proliferation The expansion of a mast cell population by cell division. http://purl.obolibrary.org/obo/UBERON_0004582 venous system http://purl.obolibrary.org/obo/UBERON_0007798 vascular system The part of the cardiovascular system consisting of all venous vessels. In vertebrates with a double circulation, this can be divided into systemic and pulmonary portions. http://purl.obolibrary.org/obo/GO_0070666 regulation of mast cell proliferation http://purl.obolibrary.org/obo/GO_0070663 regulation of leukocyte proliferation Any process that modulates the frequency, rate or extent of mast cell proliferation. http://purl.obolibrary.org/obo/UBERON_0004590 sphincter muscle http://purl.obolibrary.org/obo/UBERON_0001630 muscle organ A structure, usually a circular muscle, that normally maintains constriction of a natural body passage or orifice and which relaxes as required by normal physiological functioning. http://purl.obolibrary.org/obo/GO_0070667 negative regulation of mast cell proliferation http://purl.obolibrary.org/obo/GO_0070666 regulation of mast cell proliferation Any process that stops, prevents or reduces the rate or extent of mast cell proliferation. http://purl.obolibrary.org/obo/UBERON_0004637 otic capsule http://purl.obolibrary.org/obo/UBERON_0010363 endochondral element The capsule surrounding the inner ear mechanism. http://purl.obolibrary.org/obo/GO_0070668 positive regulation of mast cell proliferation http://purl.obolibrary.org/obo/GO_0070666 regulation of mast cell proliferation Any process that activates or increases the rate or extent of mast cell proliferation. http://purl.obolibrary.org/obo/UBERON_0004638 blood vessel endothelium http://purl.obolibrary.org/obo/UBERON_0004852 cardiovascular system endothelium An endothelium that lines the blood vasculature. Other endothelia may line lymph vessels, the heart. http://purl.obolibrary.org/obo/GO_0070820 tertiary granule http://purl.obolibrary.org/obo/GO_0030141 secretory granule A secretory granule that contains cathepsin and gelatinase and is readily exocytosed upon cell activation; found primarily in mature neutrophil cells. http://purl.obolibrary.org/obo/UBERON_0004639 renal afferent arteriole http://purl.obolibrary.org/obo/UBERON_0003644 kidney arterial blood vessel The blood vessels that branch from the kidney interlobular artery, convey blood to the glomerular capillaries, and play an important role in the regulation of blood pressure as a part of the tubuloglomerular feedback mechanism. http://purl.obolibrary.org/obo/UBERON_0004640 renal efferent arteriole http://purl.obolibrary.org/obo/UBERON_0003644 kidney arterial blood vessel The blood vessels that convey blood from the glomerulocapillary network to the capillary bed of the proximal convoluted tubule. http://purl.obolibrary.org/obo/UBERON_0004641 spleen capsule http://purl.obolibrary.org/obo/UBERON_0003893 capsule The connective tissue that surrounds the spleen. http://purl.obolibrary.org/obo/GO_0070821 tertiary granule membrane http://purl.obolibrary.org/obo/GO_0030667 secretory granule membrane The lipid bilayer surrounding a tertiary granule. http://purl.obolibrary.org/obo/UBERON_0004642 third ventricle ependyma http://purl.obolibrary.org/obo/UBERON_0005357 brain ependyma An ependyma that is part of a third ventricle [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0070830 bicellular tight junction assembly http://purl.obolibrary.org/obo/GO_0120192 tight junction assembly The aggregation, arrangement and bonding together of a set of components to form a tight junction, an occluding cell-cell junction that is composed of a branching network of sealing strands that completely encircles the apical end of each cell in an epithelial sheet. http://purl.obolibrary.org/obo/UBERON_0004643 lateral ventricle ependyma http://purl.obolibrary.org/obo/UBERON_0005357 brain ependyma An ependyma that is part of a lateral ventricle [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0070831 basement membrane assembly http://purl.obolibrary.org/obo/GO_0085029 extracellular matrix assembly The aggregation, arrangement and bonding together of a set of components to form a basement membrane, a part of the extracellular region that consists of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue. http://purl.obolibrary.org/obo/UBERON_0004644 fourth ventricle ependyma http://purl.obolibrary.org/obo/UBERON_0005357 brain ependyma An ependyma that is part of a fourth ventricle [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0070857 regulation of bile acid biosynthetic process http://purl.obolibrary.org/obo/GO_0050810 regulation of steroid biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids. http://purl.obolibrary.org/obo/UBERON_0004645 urinary bladder urothelium http://purl.obolibrary.org/obo/UBERON_0003350 epithelium of mucosa The epithelial lining of the luminal space of the urinary bladder. http://purl.obolibrary.org/obo/GO_0070858 negative regulation of bile acid biosynthetic process http://purl.obolibrary.org/obo/GO_0070857 regulation of bile acid biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids. http://purl.obolibrary.org/obo/UBERON_0004647 liver lobule http://purl.obolibrary.org/obo/UBERON_0000064 organ part The polygonal structure of the liver that consists of hepatocytes radiating outward from a hepatic vein. http://purl.obolibrary.org/obo/GO_0070859 positive regulation of bile acid biosynthetic process http://purl.obolibrary.org/obo/GO_0070857 regulation of bile acid biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids. http://purl.obolibrary.org/obo/UBERON_0004648 esophagus muscularis mucosa http://purl.obolibrary.org/obo/UBERON_0006676 muscularis mucosa A muscularis mucosa that is part of a esophagus. http://purl.obolibrary.org/obo/GO_0070942 neutrophil mediated cytotoxicity http://purl.obolibrary.org/obo/GO_0002446 neutrophil mediated immunity The directed killing of a target cell by a neutrophil. http://purl.obolibrary.org/obo/UBERON_0004650 tongue keratinized epithelium http://purl.obolibrary.org/obo/UBERON_0012329 keratinized stratified squamous epithelium A keratinized stratified squamous epithelium that is part of a tongue. http://purl.obolibrary.org/obo/GO_0070948 regulation of neutrophil mediated cytotoxicity http://purl.obolibrary.org/obo/GO_0002886 regulation of myeloid leukocyte mediated immunity Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a target cell, the directed killing of a target cell by a neutrophil. http://purl.obolibrary.org/obo/UBERON_0004652 humerus diaphysis http://purl.obolibrary.org/obo/UBERON_0004769 diaphysis The body or shaft of the humerus is almost cylindrical in the upper half of its extent, prismatic and flattened below, and has three borders and three surfaces. http://purl.obolibrary.org/obo/GO_0070954 negative regulation of neutrophil mediated cytotoxicity http://purl.obolibrary.org/obo/GO_0070948 regulation of neutrophil mediated cytotoxicity Any process that decreases the frequency, rate or extent of the directed killing of a target cell by a neutrophil. http://purl.obolibrary.org/obo/UBERON_0004663 aorta wall http://purl.obolibrary.org/obo/UBERON_0035965 wall of blood vessel An anatomical wall that is part of an aorta, enclosing the luminal space. http://purl.obolibrary.org/obo/UBERON_0004664 aorta tunica adventitia http://purl.obolibrary.org/obo/UBERON_0005734 tunica adventitia of blood vessel The outermost layer of the aorta wall, containing connective tissue and collagen and elastic fibers. http://purl.obolibrary.org/obo/GO_0070960 positive regulation of neutrophil mediated cytotoxicity http://purl.obolibrary.org/obo/GO_0070948 regulation of neutrophil mediated cytotoxicity Any process that increases the frequency, rate or extent of the directed killing of a target cell by a neutrophil. http://purl.obolibrary.org/obo/UBERON_0004665 muscular coat of seminal vesicle http://purl.obolibrary.org/obo/UBERON_0006660 muscular coat A muscular coat that is part of a seminal vesicle [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0070978 voltage-gated calcium channel complex assembly http://purl.obolibrary.org/obo/GO_0065003 protein-containing complex assembly Cellular protein complex assembly that results in the formation of a voltage-gated calcium channel complex. http://purl.obolibrary.org/obo/UBERON_0004666 interventricular septum membranous part http://purl.obolibrary.org/obo/UBERON_0005983 heart layer The membranous portion of the wall between the two lower chambers of the heart. http://purl.obolibrary.org/obo/GO_0071166 ribonucleoprotein complex localization http://purl.obolibrary.org/obo/GO_0051641 cellular localization Any process in which a ribonucleoprotein complex is transported to, or maintained in, a specific location within a cell. http://purl.obolibrary.org/obo/UBERON_0004667 interventricular septum muscular part http://purl.obolibrary.org/obo/UBERON_0002385 muscle tissue The muscular portion of the wall between the two lower chambers of the heart. http://purl.obolibrary.org/obo/UBERON_0004668 fourth ventricle aperture http://purl.obolibrary.org/obo/UBERON_0000161 orifice One of: the 4th ventricle median or lateral apertures. http://purl.obolibrary.org/obo/GO_0071168 protein localization to chromatin http://purl.obolibrary.org/obo/GO_0034502 protein localization to chromosome Any process in which a protein is transported to, or maintained at, a part of a chromosome that is organized into chromatin. http://purl.obolibrary.org/obo/UBERON_0004670 ependyma http://purl.obolibrary.org/obo/UBERON_0010371 ecto-epithelium The thin epithelium-like membrane composed of ependymal cells that lines the ventricular system of the brain and the spinal cord. http://purl.obolibrary.org/obo/GO_0071169 establishment of protein localization to chromatin http://purl.obolibrary.org/obo/GO_0070199 establishment of protein localization to chromosome The directed movement of a protein to a part of a chromosome that is organized into chromatin. http://purl.obolibrary.org/obo/UBERON_0004673 trigeminal nerve root http://purl.obolibrary.org/obo/UBERON_0006843 root of cranial nerve A nerve root that extends_fibers_into a trigeminal nerve. http://purl.obolibrary.org/obo/GO_0071214 cellular response to abiotic stimulus http://purl.obolibrary.org/obo/GO_0104004 cellular response to environmental stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (non-living) stimulus. http://purl.obolibrary.org/obo/UBERON_0004674 facial nerve root http://purl.obolibrary.org/obo/UBERON_0006843 root of cranial nerve A nerve root that extends_fibers_into a facial nerve. http://purl.obolibrary.org/obo/GO_0071229 cellular response to acid chemical http://purl.obolibrary.org/obo/GO_0070887 cellular response to chemical stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by the chemical structure of the anion portion of the dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form. http://purl.obolibrary.org/obo/UBERON_0004675 hypoglossal nerve root http://purl.obolibrary.org/obo/UBERON_0006843 root of cranial nerve A nerve root that extends_fibers_into a hypoglossal nerve. http://purl.obolibrary.org/obo/GO_0071277 cellular response to calcium ion http://purl.obolibrary.org/obo/GO_0071248 cellular response to metal ion Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus. http://purl.obolibrary.org/obo/UBERON_0004679 dentate gyrus molecular layer http://purl.obolibrary.org/obo/UBERON_0002304 layer of dentate gyrus The molecular layer of the dentate gyrus that is bounded by the pial surface superficially and the dentate gyrus granule cell layer deep. It is divided into 2 or more sublayers. http://purl.obolibrary.org/obo/GO_0071318 cellular response to ATP http://purl.obolibrary.org/obo/GO_1901701 cellular response to oxygen-containing compound Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ATP (adenosine 5'-triphosphate) stimulus. http://purl.obolibrary.org/obo/UBERON_0004684 raphe nuclei http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain The raphe nuclei are thin plates of cells in and immediately adjacent to the sagittal plane. http://purl.obolibrary.org/obo/GO_0071326 cellular response to monosaccharide stimulus http://purl.obolibrary.org/obo/GO_0071322 cellular response to carbohydrate stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monosaccharide stimulus. http://purl.obolibrary.org/obo/UBERON_0004688 costo-cervical trunk http://purl.obolibrary.org/obo/UBERON_0001637 artery The costocervical trunk arises from the upper and back part of the subclavian artery, behind the scalenus anterior on the right side, and medial to that muscle on the left side. Passing backward, it splits into the deep cervical artery and the supreme intercostal artery (or the Highest intercostal artery), which descends behind the pleura in front of the necks of the first and second ribs, and anastomoses with the first aortic intercostal (3rd posterior intercostal artery). As it crosses the neck of the first rib it lies medial to the anterior division of the first thoracic nerve, and lateral to the first thoracic ganglion of the sympathetic trunk. In the first intercostal space, it gives off a branch which is distributed in a manner similar to the distribution of the aortic intercostals. The branch for the second intercostal space usually joins with one from the highest aortic intercostal artery. This branch is not constant, but is more commonly found on the right side; when absent, its place is supplied by an intercostal branch from the aorta. Each intercostal gives off a posterior branch which goes to the posterior vertebral muscles, and sends a small spinal branch through the corresponding intervertebral foramen to the medulla spinalis and its membranes. [WP,unvetted]. http://purl.obolibrary.org/obo/GO_0071384 cellular response to corticosteroid stimulus http://purl.obolibrary.org/obo/GO_0071383 cellular response to steroid hormone stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosteroid hormone stimulus. A corticosteroid is a steroid hormone that is produced in the adrenal cortex. Corticosteroids are involved in a wide range of physiologic systems such as stress response, immune response and regulation of inflammation, carbohydrate metabolism, protein catabolism, blood electrolyte levels, and behavior. They include glucocorticoids and mineralocorticoids. http://purl.obolibrary.org/obo/UBERON_0004692 external naris epithelium http://purl.obolibrary.org/obo/UBERON_0035036 naris epithelium An epithelium that is part of an external naris [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0071389 cellular response to mineralocorticoid stimulus http://purl.obolibrary.org/obo/GO_0071384 cellular response to corticosteroid stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mineralocorticoid stimulus. Mineralocorticoids are hormonal C21 corticosteroids synthesized from cholesterol and characterized by their similarity to aldosterone. Mineralocorticoids act primarily on water and electrolyte balance. http://purl.obolibrary.org/obo/UBERON_0004693 Peyer's patch epithelium http://purl.obolibrary.org/obo/UBERON_0001277 intestinal epithelium The specialized epithelial layer covering the entire Peyer's patch, including both the follicular and interfollicular areas and forming part of the gut-associated lymphoid tissue. http://purl.obolibrary.org/obo/GO_0071392 cellular response to estradiol stimulus http://purl.obolibrary.org/obo/GO_1901701 cellular response to oxygen-containing compound Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen. http://purl.obolibrary.org/obo/UBERON_0004695 arterial system smooth muscle http://purl.obolibrary.org/obo/UBERON_0001135 smooth muscle tissue A portion of smooth muscle tissue that is part of an arterial system [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0071393 cellular response to progesterone stimulus http://purl.obolibrary.org/obo/GO_1901655 cellular response to ketone Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a progesterone stimulus. http://purl.obolibrary.org/obo/UBERON_0004696 venous system smooth muscle http://purl.obolibrary.org/obo/UBERON_0004237 blood vessel smooth muscle A portion of smooth muscle tissue that is part of a venous system [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0071394 cellular response to testosterone stimulus http://purl.obolibrary.org/obo/GO_1901655 cellular response to ketone Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a testosterone stimulus. http://purl.obolibrary.org/obo/UBERON_0004697 Peyer's patch germinal center http://purl.obolibrary.org/obo/UBERON_0010754 germinal center Area of the Peyer's patch where B cells proliferate and differentiate into plasma cells. http://purl.obolibrary.org/obo/GO_0071398 cellular response to fatty acid http://purl.obolibrary.org/obo/GO_1901701 cellular response to oxygen-containing compound Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fatty acid stimulus. http://purl.obolibrary.org/obo/UBERON_0004698 vena cava endothelium http://purl.obolibrary.org/obo/UBERON_0001919 endothelium of vein An endothelium that is part of a vena cava [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0071402 cellular response to lipoprotein particle stimulus http://purl.obolibrary.org/obo/GO_0051716 cellular response to stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoprotein particle stimulus. http://purl.obolibrary.org/obo/UBERON_0004699 outflow tract endothelium http://purl.obolibrary.org/obo/UBERON_0008307 heart endothelium An endothelium that is part of a outflow tract [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004700 arterial system endothelium http://purl.obolibrary.org/obo/UBERON_0004852 cardiovascular system endothelium An endothelium that is part of an arterial system [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0071420 cellular response to histamine http://purl.obolibrary.org/obo/GO_1901699 cellular response to nitrogen compound Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histamine stimulus. Histamine, the biogenic amine 2-(1H-imidazol-4-yl)ethanamine, is involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter. http://purl.obolibrary.org/obo/UBERON_0004701 venous system endothelium http://purl.obolibrary.org/obo/UBERON_0004852 cardiovascular system endothelium An endothelium that is part of a venous system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004702 respiratory system blood vessel endothelium http://purl.obolibrary.org/obo/UBERON_0004807 respiratory system epithelium A blood vessel endothelium that is part of a respiratory system [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0071425 hematopoietic stem cell proliferation http://purl.obolibrary.org/obo/GO_0072089 stem cell proliferation The expansion of a hematopoietic stem cell population by cell division. A hematopoietic stem cell is a stem cell from which all cells of the lymphoid and myeloid lineages develop. http://purl.obolibrary.org/obo/UBERON_0004704 bone fossa http://purl.obolibrary.org/obo/UBERON_0002553 anatomical cavity A depression or hollow in a bone[WP]. http://purl.obolibrary.org/obo/GO_0071450 cellular response to oxygen radical http://purl.obolibrary.org/obo/GO_0034614 cellular response to reactive oxygen species Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen radical stimulus. An oxygen radical is any oxygen species that carries a free electron; examples include hydroxyl radicals and the superoxide anion. http://purl.obolibrary.org/obo/UBERON_0004706 bulbus cordis http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure A transient fetal dilation of the distal (or cranial) heart tube located where the arterial trunk joins the ventral roots of the aortic arches. http://purl.obolibrary.org/obo/GO_0071542 dopaminergic neuron differentiation http://purl.obolibrary.org/obo/GO_0030182 neuron differentiation The process in which a neuroblast acquires the specialized structural and functional features of a dopaminergic neuron, a neuron that secretes dopamine. http://purl.obolibrary.org/obo/UBERON_0004707 pharyngula stage http://purl.obolibrary.org/obo/UBERON_0000105 life cycle stage A chordate developmental stage that follows the blastula, gastrula and neurula stages. At the pharyngula stage, all vertebrate embryos show remarkable similarities. http://purl.obolibrary.org/obo/GO_0071599 otic vesicle development http://purl.obolibrary.org/obo/GO_0048839 inner ear development The process whose specific outcome is the progression of the otic vesicle over time, from its formation to the mature structure. The otic vesicle is a transient embryonic structure formed during development of the vertebrate inner ear. http://purl.obolibrary.org/obo/UBERON_0004708 paired limb/fin http://purl.obolibrary.org/obo/UBERON_0010314 structure with developmental contribution from neural crest An appendage that is part of an appendage girdle complex. http://purl.obolibrary.org/obo/GO_0071623 negative regulation of granulocyte chemotaxis http://purl.obolibrary.org/obo/GO_0071622 regulation of granulocyte chemotaxis Any process that decreases the rate, frequency or extent of granulocyte chemotaxis. Granulocyte chemotaxis is the movement of a granulocyte in response to an external stimulus. http://purl.obolibrary.org/obo/UBERON_0004709 pelvic appendage http://purl.obolibrary.org/obo/UBERON_0004708 paired limb/fin Paired appendage that consists of the posterior appendicular skeleton and associated soft and hard tissues, but excludes the pelvic girdle and its associated soft and hard tissues. http://purl.obolibrary.org/obo/GO_0071624 positive regulation of granulocyte chemotaxis http://purl.obolibrary.org/obo/GO_0071622 regulation of granulocyte chemotaxis Any process that increases the rate, frequency or extent of granulocyte chemotaxis. Granulocyte chemotaxis is the movement of a granulocyte in response to an external stimulus. http://purl.obolibrary.org/obo/UBERON_0004710 pectoral appendage http://purl.obolibrary.org/obo/UBERON_0004708 paired limb/fin Paired appendage that consists of the anterior appendicular skeleton and associated soft and hard tissues, but excludes the pectoral girdle and its associated soft and hard tissues. http://purl.obolibrary.org/obo/GO_0071626 mastication http://purl.obolibrary.org/obo/GO_0022600 digestive system process The process of biting and mashing food with the teeth prior to swallowing. http://purl.obolibrary.org/obo/UBERON_0004711 jugular vein http://purl.obolibrary.org/obo/UBERON_0001638 vein The jugular veins are veins that bring deoxygenated blood from the head back to the heart via the superior vena cava. http://purl.obolibrary.org/obo/GO_0071670 smooth muscle cell chemotaxis http://purl.obolibrary.org/obo/GO_0014909 smooth muscle cell migration The directed movement of a smooth muscle cell in response to an external stimulus. http://purl.obolibrary.org/obo/UBERON_0004715 annulus fibrosus disci intervertebralis http://purl.obolibrary.org/obo/UBERON_0006444 annulus fibrosus The ring of fibrocartilage and fibrous tissue forming the circumference of the intervertebral disc; surrounds the nucleus pulposus, which is prone to herniation when the annulus fibrosus is compromised. http://purl.obolibrary.org/obo/GO_0071671 regulation of smooth muscle cell chemotaxis http://purl.obolibrary.org/obo/GO_0014910 regulation of smooth muscle cell migration Any process that modulates the frequency, rate, or extent of smooth muscle cell chemotaxis. http://purl.obolibrary.org/obo/UBERON_0004716 conceptus http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure The embryo and its adnexa (appendages or adjunct parts) or associated membranes (i.e. the products of conception) The conceptus includes all structures that develop from the zygote, both embryonic and extraembryonic. It includes the embryo as well as the embryonic part of the placenta and its associated membranes - amnion, chorion (gestational sac), and yolk sac[WP]. http://purl.obolibrary.org/obo/GO_0071672 negative regulation of smooth muscle cell chemotaxis http://purl.obolibrary.org/obo/GO_0071671 regulation of smooth muscle cell chemotaxis Any process that stops, prevents, or reduces the frequency, rate, or extent of smooth muscle cell chemotaxis. http://purl.obolibrary.org/obo/UBERON_0004719 kidney arcuate vein http://purl.obolibrary.org/obo/UBERON_0014401 renal venous blood vessel Any of the veins that parallel the arcuate arteries, receive blood from the interlobular veins and straight venules, and terminate in the interlobar veins. http://purl.obolibrary.org/obo/GO_0071673 positive regulation of smooth muscle cell chemotaxis http://purl.obolibrary.org/obo/GO_0071671 regulation of smooth muscle cell chemotaxis Any process that activates or increases the frequency, rate, or extent of smooth muscle cell chemotaxis. http://purl.obolibrary.org/obo/UBERON_0004721 crista ampullaris http://purl.obolibrary.org/obo/UBERON_0000020 sense organ The crista ampullaris is the sensory organ of rotation located in the semicircular canal of the inner ear. The function of the crista ampullaris is to sense angular acceleration and deceleration. http://purl.obolibrary.org/obo/GO_0071676 negative regulation of mononuclear cell migration http://purl.obolibrary.org/obo/GO_0071675 regulation of mononuclear cell migration Any process that decreases the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body. http://purl.obolibrary.org/obo/UBERON_0004723 interlobular artery http://purl.obolibrary.org/obo/UBERON_0003644 kidney arterial blood vessel The branches of the arcuate arteries of the kidney that radiate outward throught the renal columns and supply the glomeruli[MP]. The first set of renal bloodvessels, the interlobular arteries (or cortical radiate arteries, or cortical radial arteries), are given off at right angles from the side of the arcuate arteries looking toward the cortical substance, and pass directly outward between the medullary rays to reach the fibrous tunic, where they end in the capillary network of this part. These vessels do not anastomose with each other, but form what are called end-arteries. In their outward course they give off lateral branches; these are the afferent vessels for the renal corpuscles; they enter the capsule, and end in the glomerulus. From each tuft the corresponding efferent vessel arises, and, having made its egress from the capsule near to the point where the afferent vessel enters, breaks up into a number of branches, which form a dense plexus within Bowman's capsule. http://purl.obolibrary.org/obo/GO_0071677 positive regulation of mononuclear cell migration http://purl.obolibrary.org/obo/GO_0071675 regulation of mononuclear cell migration Any process that increases the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body. http://purl.obolibrary.org/obo/UBERON_0004725 piriform cortex http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain The subdivision of the laminated olfactory cortex with only three main layers that receive monosynaptic input from the olfactory bulb via the lateral olfactory tract; it is located bilaterally in the ventrolateral forebrain and is commonly divided into anterior and posterior regions. http://purl.obolibrary.org/obo/GO_0071696 ectodermal placode development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of an ectodermal placode over time from its initial formation until its mature state. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm. http://purl.obolibrary.org/obo/UBERON_0004726 vasa recta http://purl.obolibrary.org/obo/UBERON_0006544 kidney vasculature A group of microvessels that are part of the kidney. A vasa recta has a hairpin-like shape, entering the renal medulla as the straight arterioles and surrounds the loop of Henle, forming a capillary network. Finally it leaves the renal medulla to ascend to the cortex as the straight venules. The primary function of the vasa recta is to facilitate countercurrent exchange, which is essential for the kidney's ability to concentrate urine http://purl.obolibrary.org/obo/GO_0071697 ectodermal placode morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structures of an ectodermal placode are generated and organized. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm. http://purl.obolibrary.org/obo/UBERON_0004727 cochlear nerve http://purl.obolibrary.org/obo/UBERON_0011779 nerve of head region A nerve in the head that carries signals from the cochlea of the inner ear to the brain. It is part of the vestibulocochlear nerve, the 8th cranial nerve which is found in higher vertebrates; the other portion of the 8th cranial nerve is the vestibular nerve which carries spatial orientation information from the semicircular canals. The cochlear nerve is a sensory nerve, one which conducts to the brain information about the environment, in this case acoustic energy impinging on the tympanic membrane. The cochlear nerve arises from within the cochlea and extends to the brainstem, where its fibers make contact with the cochlear nucleus, the next stage of neural processing in the auditory system[WP]. http://purl.obolibrary.org/obo/GO_0071698 olfactory placode development http://purl.obolibrary.org/obo/GO_0071696 ectodermal placode development The progression of the olfactory placode over time from its initial formation until its mature state. The olfactory placode is a thickening of the neural ectoderm in the head region of the vertebrate embryo which develops into the olfactory region of the nasal cavity. http://purl.obolibrary.org/obo/UBERON_0004731 neuromere http://purl.obolibrary.org/obo/UBERON_0004732 segmental subdivision of nervous system A transverse unitary subdivision of the neural tube that shares a common dorsoventral structure (floor, basal, alar, and roof plates), but each having differential molecular identities and fates; they comprise the secondary prosencephalon, diencephalon (prosomeres), the midbrain (mesomeres), and the hindbrain (rhombomeres). http://purl.obolibrary.org/obo/GO_0071700 olfactory placode maturation http://purl.obolibrary.org/obo/GO_0071695 anatomical structure maturation A developmental process, independent of morphogenetic (shape) change, that is required for the olfactory placode to attain its fully functional state. The olfactory placode is a thickening of the neural ectoderm in the head region of the vertebrate embryo which develops into the olfactory region of the nasal cavity. http://purl.obolibrary.org/obo/UBERON_0004732 segmental subdivision of nervous system http://purl.obolibrary.org/obo/UBERON_0000063 organ subunit Any segmental subdivision of a nervous system. Includes metameric developmental segments, such as vertebrates neuromeres. http://purl.obolibrary.org/obo/GO_0071707 immunoglobulin heavy chain V-D-J recombination http://purl.obolibrary.org/obo/GO_0033152 immunoglobulin V(D)J recombination The process in which immunoglobulin heavy chain V, D, and J gene segments are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS). http://purl.obolibrary.org/obo/UBERON_0004733 segmental subdivision of hindbrain http://purl.obolibrary.org/obo/UBERON_0004732 segmental subdivision of nervous system An organ subunit that is part of a hindbrain [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0071708 immunoglobulin light chain V-J recombination http://purl.obolibrary.org/obo/GO_0033152 immunoglobulin V(D)J recombination The process in which immunoglobulin light chain V and J gene segments are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS). http://purl.obolibrary.org/obo/UBERON_0004734 gastrula http://purl.obolibrary.org/obo/UBERON_0000922 embryo Organism at the gastrula stage. http://purl.obolibrary.org/obo/GO_0071732 cellular response to nitric oxide http://purl.obolibrary.org/obo/GO_1902170 cellular response to reactive nitrogen species Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitric oxide stimulus. http://purl.obolibrary.org/obo/UBERON_0004736 metanephric glomerulus http://purl.obolibrary.org/obo/UBERON_0000074 renal glomerulus Glomerulus of the mature vertebrate kidney, or metanephros. http://purl.obolibrary.org/obo/GO_0071735 IgG immunoglobulin complex http://purl.obolibrary.org/obo/GO_0019814 immunoglobulin complex A protein complex composed of two identical immunoglobulin heavy chains of an IgG isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgG immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph. http://purl.obolibrary.org/obo/UBERON_0004737 metanephric collecting duct http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure A collecting duct of renal tubule that is part of a metanephros [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0071736 IgG immunoglobulin complex, circulating http://purl.obolibrary.org/obo/GO_0071735 IgG immunoglobulin complex A protein complex composed of two identical immunoglobulin heavy chains of an IgG isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph. http://purl.obolibrary.org/obo/UBERON_0004738 metanephric juxtaglomerular apparatus http://purl.obolibrary.org/obo/UBERON_0002303 juxtaglomerular apparatus Juxtaglomerular apparatus of the mature vertebrate kidney, or metanephros. http://purl.obolibrary.org/obo/GO_0071738 IgD immunoglobulin complex http://purl.obolibrary.org/obo/GO_0019814 immunoglobulin complex A protein complex composed of two identical immunoglobulin heavy chains of the IgD isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgD immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph. http://purl.obolibrary.org/obo/UBERON_0004739 pronephric glomerulus http://purl.obolibrary.org/obo/UBERON_0000074 renal glomerulus The glomus forms from the splanchnic intermediate mesoderm and is the vascularized filtration unit, filtering the blood before it enters the tubules. The glomus is external to the nephron and extends over more than one body segment. http://purl.obolibrary.org/obo/GO_0071739 IgD immunoglobulin complex, circulating http://purl.obolibrary.org/obo/GO_0071738 IgD immunoglobulin complex A protein complex composed of two identical immunoglobulin heavy chains of the IgD isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph. http://purl.obolibrary.org/obo/UBERON_0004742 dentary http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure The dentary is a dermal bone that forms the antero-lateral part of the lower jaw in fishes and amphibians, extending to the whole lower jaw in mammals[VHOG,modified]. http://purl.obolibrary.org/obo/UBERON_0004753 scapulocoracoid http://purl.obolibrary.org/obo/UBERON_0004765 skeletal element Skeletal element that consists of the scapula and the coracoid[VSAO, modified]. http://purl.obolibrary.org/obo/GO_0071742 IgE immunoglobulin complex http://purl.obolibrary.org/obo/GO_0019814 immunoglobulin complex A protein complex composed of two identical immunoglobulin heavy chains of the IgE isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgE immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph. http://purl.obolibrary.org/obo/UBERON_0004755 skeletal tissue http://purl.obolibrary.org/obo/UBERON_0002384 connective tissue A specialized form of connective tissue in which the extracellular matrix is firm, providing the tissue with resilience, and/or mineralized and that functions in mechanical and structural support.[VSAO]. http://purl.obolibrary.org/obo/GO_0071743 IgE immunoglobulin complex, circulating http://purl.obolibrary.org/obo/GO_0071742 IgE immunoglobulin complex A protein complex composed of two identical immunoglobulin heavy chains of the IgE isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph. http://purl.obolibrary.org/obo/UBERON_0004756 dermal skeletal element http://purl.obolibrary.org/obo/UBERON_0004765 skeletal element Dermis-derived entity that is made of skeletal tissue. http://purl.obolibrary.org/obo/GO_0071745 IgA immunoglobulin complex http://purl.obolibrary.org/obo/GO_0019814 immunoglobulin complex A protein complex composed of two identical immunoglobulin heavy chains of the IgA isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and sometimes complexed with J chain or J chain and secretory component. An IgA immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph. http://purl.obolibrary.org/obo/UBERON_0004757 rectal salt gland http://purl.obolibrary.org/obo/UBERON_0004758 salt gland An evagination of the terminal portion of the intestine that is capable of secreting high concentrations of excess sodium chloride. http://purl.obolibrary.org/obo/GO_0071746 IgA immunoglobulin complex, circulating http://purl.obolibrary.org/obo/GO_0071745 IgA immunoglobulin complex A protein complex composed of two identical immunoglobulin heavy chains of an IgA isotype and two identical immunoglobulin light chains, held together by disulfide bonds, sometimes complexed with J chain or J chain and secretory component, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph. http://purl.obolibrary.org/obo/UBERON_0004758 salt gland http://purl.obolibrary.org/obo/UBERON_0002530 gland An organ for excreting excess salts. It is found in elasmobranchs, seabirds, and some reptiles.[WP]. http://purl.obolibrary.org/obo/GO_0071753 IgM immunoglobulin complex http://purl.obolibrary.org/obo/GO_0019814 immunoglobulin complex A protein complex composed of two identical immunoglobulin heavy chains of the IgM isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and in its circulating form complexed with J chain in polymeric forms. An IgM immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph. http://purl.obolibrary.org/obo/UBERON_0004759 cranial salt gland http://purl.obolibrary.org/obo/UBERON_0004758 salt gland A salt gland located in the cranium or head region. http://purl.obolibrary.org/obo/GO_0071754 IgM immunoglobulin complex, circulating http://purl.obolibrary.org/obo/GO_0071753 IgM immunoglobulin complex A polymer of five or six IgM core units each composed of two identical immunoglobulin heavy chains of the IgM isotype and two identical immunoglobulin light chains, held together by disulfide bonds; the individual IgM core units are held together via disulfide bonds with a single J chain polypeptide acting as a bridge between two of the polymeric units. Circulating IgM is present in the extracellular space, in mucosal areas or other tissues, or in the blood or lymph. http://purl.obolibrary.org/obo/UBERON_0004760 gland of anal canal http://purl.obolibrary.org/obo/UBERON_0003408 gland of digestive tract A gland that is part of an anal canal [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0071764 nuclear outer membrane organization http://purl.obolibrary.org/obo/GO_0071763 nuclear membrane organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear outer membrane. http://purl.obolibrary.org/obo/UBERON_0004761 cartilaginous neurocranium http://purl.obolibrary.org/obo/UBERON_0000075 subdivision of skeletal system The primitive cartilagionous skeletal structure of the fetal skull that grows to envelop the rapidly growing embyonic brain. In humans, the chondrocranium begins forming at 28 days from mesenchymal condensations and is fully formed between week 7 and 9 of fetal development. While the majority of the chondrocranium is succeeded by the bony skull in most higher vertebrates, some components do persist into adulthood.[1] In Cartilagious fishes and Agnathans, the chondrocranium persist throughout life.[2] Embryologically, the chondrocranium represent the basal cranial structure, and lay the base for the formation of the endocranium in higher vertebrates[WP]. http://purl.obolibrary.org/obo/GO_0071814 protein-lipid complex binding http://purl.obolibrary.org/obo/GO_0044877 protein-containing complex binding Binding to a protein-lipid complex, any macromolecular complex that contains both protein and lipid molecules. http://purl.obolibrary.org/obo/UBERON_0004763 endochondral bone tissue http://purl.obolibrary.org/obo/UBERON_0002481 bone tissue Replacement bone tissue that forms within cartilage[VSAO, modified]. http://purl.obolibrary.org/obo/GO_0071868 cellular response to monoamine stimulus http://purl.obolibrary.org/obo/GO_1901699 cellular response to nitrogen compound Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monoamine stimulus. A monoamine is any of a group of molecular messengers that contain one amino group that is connected to an aromatic ring by ethylene group (-CH2-CH2-). Monoamines are derived from the aromatic amino acids phenylalanine, tyrosine, histidine and tryptophan. http://purl.obolibrary.org/obo/UBERON_0004764 intramembranous bone tissue http://purl.obolibrary.org/obo/UBERON_0002481 bone tissue Bone tissue that forms directly within mesenchyme, and does not replace other tissues[TAO]. Intramembranous ossification is the formation of bone in which osteoblasts secrete a collagen-proteoglycan matrix that binds calcium salts and becomes calcified[GO]. Intramembranous ossification is the way flat bones and the shell of a turtle are formed[GO]. Unlike endochondral ossification, cartilage is not present during intramembranous ossification[WP]. http://purl.obolibrary.org/obo/GO_0071869 response to catecholamine http://purl.obolibrary.org/obo/GO_0071867 response to monoamine Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catecholamine stimulus. A catecholamine is any of a group of biogenic amines that includes 4-(2-aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] and derivatives formed by substitution. http://purl.obolibrary.org/obo/UBERON_0004765 skeletal element http://purl.obolibrary.org/obo/UBERON_0000062 organ Organ consisting of skeletal tissue. Encompasses whole bones, fused bones, cartilaginious elements, teeth, dermal denticles. http://purl.obolibrary.org/obo/GO_0071870 cellular response to catecholamine stimulus http://purl.obolibrary.org/obo/GO_0071869 response to catecholamine Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catecholamine stimulus. A catecholamine is any of a group of biogenic amines that includes 4-(2-aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] and derivatives formed by substitution. http://purl.obolibrary.org/obo/UBERON_0004766 cranial bone http://purl.obolibrary.org/obo/UBERON_0001474 bone element A bone that is part of a cranium. http://purl.obolibrary.org/obo/GO_0071873 response to norepinephrine http://purl.obolibrary.org/obo/GO_0071869 response to catecholamine Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a norepinephrine stimulus. Norepinephrine is a catecholamine that has the formula C8H11NO3; it acts as a hormone, and as a neurotransmitter in most of the sympathetic nervous system. http://purl.obolibrary.org/obo/UBERON_0004767 vomerine tooth http://purl.obolibrary.org/obo/UBERON_0012070 palatal tooth A tooth that is on the vomer. http://purl.obolibrary.org/obo/GO_0071874 cellular response to norepinephrine stimulus http://purl.obolibrary.org/obo/GO_0071873 response to norepinephrine Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a norepinephrine stimulus. Norepinephrine is a catecholamine that has the formula C8H11NO3; it acts as a hormone, and as a neurotransmitter in most of the sympathetic nervous system. http://purl.obolibrary.org/obo/UBERON_0004768 bone of lower jaw http://purl.obolibrary.org/obo/UBERON_0012360 bone of jaw Any bone that is part of the lower jaw skeleton. This includes (when present): the dentary/mandible, the articular, the splenial, the suprangular. http://purl.obolibrary.org/obo/GO_0071888 macrophage apoptotic process http://purl.obolibrary.org/obo/GO_0071887 leukocyte apoptotic process Any apoptotic process in a macrophage, a mononuclear phagocyte present in a variety of tissues. http://purl.obolibrary.org/obo/UBERON_0004769 diaphysis http://purl.obolibrary.org/obo/UBERON_0005055 zone of long bone Subdivision of long bone which forms the part of the bone between the two epiphyses, excluding the metaphyses[FMA,modified]. http://purl.obolibrary.org/obo/GO_0071890 bicarbonate binding http://purl.obolibrary.org/obo/GO_0043168 anion binding Binding to bicarbonate ions (CHO3-). http://purl.obolibrary.org/obo/UBERON_0004770 articular system http://purl.obolibrary.org/obo/UBERON_0034925 anatomical collection Anatomical system that consists of all the joints of the body. http://purl.obolibrary.org/obo/GO_0071895 odontoblast differentiation http://purl.obolibrary.org/obo/GO_0060563 neuroepithelial cell differentiation The process in which a relatively unspecialized cell of neural crest origin acquires the specialized features of an odontoblast, a cell on the outer surface of the dental pulp whose biological function is the creation of dentin. http://purl.obolibrary.org/obo/UBERON_0004771 posterior nasal aperture http://purl.obolibrary.org/obo/UBERON_0010425 internal naris Opening/conduit between the nasal cavity and the nasopharynx[AAO] The choanae are separated by the vomer[WP]. http://purl.obolibrary.org/obo/GO_0071953 elastic fiber http://purl.obolibrary.org/obo/GO_0099512 supramolecular fiber An supramolecular fiber that consists of an insoluble core of polymerized tropoelastin monomers and a surrounding mantle of microfibrils. Elastic fibers provide elasticity and recoiling to tissues and organs, and maintain structural integrity against mechanical strain. http://purl.obolibrary.org/obo/UBERON_0004775 outer renal medulla vasa recta http://purl.obolibrary.org/obo/UBERON_0004726 vasa recta A vasa recta that is part of a outer medulla of kidney [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0071971 extracellular exosome assembly http://purl.obolibrary.org/obo/GO_0070925 organelle assembly The aggregation, arrangement and bonding together of a set of components to form an extracellular vesicular exosome, a membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Exosomes are defined by their size, which generally ranges from 30 nm to 100 nm. http://purl.obolibrary.org/obo/UBERON_0004776 inner renal medulla vasa recta http://purl.obolibrary.org/obo/UBERON_0004726 vasa recta A vasa recta that is part of a inner medulla of kidney [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072003 kidney rudiment formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The developmental process pertaining to the initial formation of a kidney rudiment from unspecified parts. A kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine. http://purl.obolibrary.org/obo/UBERON_0004777 respiratory system submucosa http://purl.obolibrary.org/obo/UBERON_0000009 submucosa A submucosa that is part of a respiratory system [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072007 mesangial cell differentiation http://purl.obolibrary.org/obo/GO_1904238 pericyte cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesangial cells of the kidney as it progresses from its formation to the mature state. http://purl.obolibrary.org/obo/UBERON_0004778 larynx submucosa http://purl.obolibrary.org/obo/UBERON_0004777 respiratory system submucosa A submucosa that is part of a larynx [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072008 glomerular mesangial cell differentiation http://purl.obolibrary.org/obo/GO_0072007 mesangial cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the glomerular mesangial cells of the kidney as it progresses from its formation to the mature state. http://purl.obolibrary.org/obo/UBERON_0004779 respiratory system lamina propria http://purl.obolibrary.org/obo/UBERON_0000030 lamina propria A lamina propria that is part of a respiratory system [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072009 nephron epithelium development http://purl.obolibrary.org/obo/GO_0072073 kidney epithelium development The process whose specific outcome is the progression of the nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The nephron epithelium is a tissue that covers the surface of a nephron. http://purl.obolibrary.org/obo/UBERON_0004780 gastrointestinal system lamina propria http://purl.obolibrary.org/obo/UBERON_0000030 lamina propria A lamina propria that is part of a gastrointestinal system. http://purl.obolibrary.org/obo/GO_0072010 glomerular epithelium development http://purl.obolibrary.org/obo/GO_0072009 nephron epithelium development The process whose specific outcome is the progression of the glomerular epithelium over time, from its formation to the mature structure. The glomerular epithelium is an epithelial tissue that covers the outer surfaces of the glomerulus. The glomerular epithelium consists of both parietal and visceral epithelium. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros. http://purl.obolibrary.org/obo/UBERON_0004781 gallbladder lamina propria http://purl.obolibrary.org/obo/UBERON_0000030 lamina propria A lamina propria that is part of a gallbladder [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072011 glomerular endothelium development http://purl.obolibrary.org/obo/GO_0072010 glomerular epithelium development The process whose specific outcome is the progression of the glomerular endothelium over time, from its formation to the mature structure. The glomerular endothelium is an epithelial tissue that covers the internal surfaces of the glomerulus. http://purl.obolibrary.org/obo/UBERON_0004782 gastrointestinal system serosa http://purl.obolibrary.org/obo/UBERON_0000042 serous membrane A serous membrane that is part of a digestive system [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072012 glomerulus vasculature development http://purl.obolibrary.org/obo/GO_0061440 kidney vasculature development The biological process whose specific outcome is the progression of a glomerulus vasculature from an initial condition to its mature state. This process begins with the formation of the glomerulus vasculature and ends with the mature structure. The glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the glomerulus. http://purl.obolibrary.org/obo/UBERON_0004783 gallbladder serosa http://purl.obolibrary.org/obo/UBERON_0000042 serous membrane A serous membrane that is part of a gallbladder [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072015 podocyte development http://purl.obolibrary.org/obo/GO_0072310 glomerular epithelial cell development The process whose specific outcome is the progression of a glomerular visceral epithelial cell over time, from its formation to the mature structure. A glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells. http://purl.obolibrary.org/obo/UBERON_0004784 heart ventricle wall http://purl.obolibrary.org/obo/UBERON_0037144 wall of heart An anatomical wall that is part of a cardiac ventricle [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004785 respiratory system mucosa http://purl.obolibrary.org/obo/UBERON_0000344 mucosa The mucous membrane lining the respiratory tract. http://purl.obolibrary.org/obo/GO_0072016 glomerular parietal epithelial cell development http://purl.obolibrary.org/obo/GO_0072310 glomerular epithelial cell development The process whose specific outcome is the progression of a glomerular parietal epithelial cell over time, from its formation to the mature structure. Glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. http://purl.obolibrary.org/obo/UBERON_0004786 gastrointestinal system mucosa http://purl.obolibrary.org/obo/UBERON_0000344 mucosa A mucosa that is part of a gastrointestinal system. http://purl.obolibrary.org/obo/UBERON_0004787 urethra urothelium http://purl.obolibrary.org/obo/UBERON_0002325 epithelium of urethra An urothelium that is part of a urethra [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072019 proximal convoluted tubule development http://purl.obolibrary.org/obo/GO_0072080 nephron tubule development The process whose specific outcome is the progression of the proximal convoluted tubule over time, from its formation to the mature structure. The proximal convoluted tubule is the most proximal portion of the proximal tubule and extends from the glomerular capsule to the proximal straight tubule. http://purl.obolibrary.org/obo/UBERON_0004788 kidney pelvis urothelium http://purl.obolibrary.org/obo/UBERON_0004819 kidney epithelium The epithelial lining of the luminal space of the kidney pelvis. http://purl.obolibrary.org/obo/GO_0072020 proximal straight tubule development http://purl.obolibrary.org/obo/GO_0072080 nephron tubule development The process whose specific outcome is the progression of the proximal straight tubule over time, from its formation to the mature structure. The proximal straight tubule is the part of the descending limb that extends from the proximal convoluted tubule to the descending thin tubule. http://purl.obolibrary.org/obo/UBERON_0004789 larynx mucous gland http://purl.obolibrary.org/obo/UBERON_0036225 respiratory system gland A mucous gland that is part of a larynx [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004790 skin mucous gland http://purl.obolibrary.org/obo/UBERON_0019319 exocrine gland of integumental system A mucous gland that is part of the skin. http://purl.obolibrary.org/obo/GO_0072021 ascending thin limb development http://purl.obolibrary.org/obo/GO_0072080 nephron tubule development The process whose specific outcome is the progression of an ascending thin limb over time, from its formation to the mature structure. The ascending thin limb is a segment of a nephron tubule lying in the inner medulla that is permeable to ions but not to water and has a simple epithelium; active transepithelial solute transport is absent. http://purl.obolibrary.org/obo/UBERON_0004791 thymus trabecula http://purl.obolibrary.org/obo/UBERON_0000440 trabecula The thymic connective tissue which extends into the parenchyma. http://purl.obolibrary.org/obo/GO_0072022 descending thin limb development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the descending thin limb over time, from its formation to the mature structure. The descending thin limb is a part of the loop of Henle situated just after the proximal straight tubule (S3). It extends to the tip of the loop of Henle. http://purl.obolibrary.org/obo/UBERON_0004792 secretion of endocrine pancreas http://purl.obolibrary.org/obo/UBERON_0004795 pancreas secretion A secretion that is part of a endocrine pancreas [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072023 thick ascending limb development http://purl.obolibrary.org/obo/GO_0072080 nephron tubule development The process whose specific outcome is the progression of the thick ascending limb over time, from its formation to the mature structure. The thick ascending limb is the last part of the loop of Henle. Its thick, mitochondria-rich epithelium characterizes the outer medulla, and is responsible for very avid active salt transport. At the macula densa, the thick ascending limb connects to the distal convoluted tubule. http://purl.obolibrary.org/obo/UBERON_0004793 secretion of exocrine pancreas http://purl.obolibrary.org/obo/UBERON_0004795 pancreas secretion A secretion that is part of a exocrine pancreas [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004794 esophagus secretion http://purl.obolibrary.org/obo/UBERON_0000456 secretion of exocrine gland A secretion that is part of a esophagus [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072024 macula densa development http://purl.obolibrary.org/obo/GO_0072009 nephron epithelium development The process whose specific outcome is the progression of the macula densa over time, from its formation to the mature structure. The macula densa is an area of specialized cells in the distal tubule that makes contact with the vascular pole of the glomerulus. http://purl.obolibrary.org/obo/UBERON_0004795 pancreas secretion http://purl.obolibrary.org/obo/UBERON_0000456 secretion of exocrine gland A secretion that is part of a pancreas [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072025 distal convoluted tubule development http://purl.obolibrary.org/obo/GO_0072080 nephron tubule development The process whose specific outcome is the progression of the distal convoluted tubule over time, from its formation to the mature structure. The distal convoluted tubule is the first segment of the nephron lying just downstream from the loop of Henle, immediately after the macula densa. Among other functions, in humans it is responsible for the reabsorption of about 5% of filtered sodium via the thiazide-sensitive Na-Cl symporter. http://purl.obolibrary.org/obo/UBERON_0004796 prostate gland secretion http://purl.obolibrary.org/obo/UBERON_0006530 seminal fluid A bodily secretion that is produced by the prostate gland. http://purl.obolibrary.org/obo/GO_0072027 connecting tubule development http://purl.obolibrary.org/obo/GO_0072080 nephron tubule development The process whose specific outcome is the progression of the connecting tubule over time, from its formation to the mature structure. The connecting tubule is a tubular segment of the nephron; it connects the distal convoluted tubule to the collecting duct. http://purl.obolibrary.org/obo/UBERON_0004797 blood vessel layer http://purl.obolibrary.org/obo/UBERON_0004923 organ component layer Any of the tissue layers that comprise a blood vessel. Examples: tunica media, tunica adventitia. http://purl.obolibrary.org/obo/GO_0072029 long nephron development http://purl.obolibrary.org/obo/GO_0072006 nephron development The process whose specific outcome is the progression of a long nephron over time, from its formation to the mature structure. Long nephrons are associated with juxtamedullary glomeruli and extend into the inner medulla. http://purl.obolibrary.org/obo/UBERON_0004798 respiratory system basal lamina http://purl.obolibrary.org/obo/UBERON_0000482 basal lamina of epithelium A basal lamina that is part of a respiratory system [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072030 short nephron development http://purl.obolibrary.org/obo/GO_0072006 nephron development The process whose specific outcome is the progression of a short nephron over time, from its formation to the mature structure. Short nephrons are associated with mid-cortical and superficial glomeruli, are situated entirely in the outer medulla, and have no thin ascending limb. http://purl.obolibrary.org/obo/UBERON_0004799 trachea basal lamina http://purl.obolibrary.org/obo/UBERON_0004798 respiratory system basal lamina A basal lamina that is part of a respiratory airway [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072031 proximal convoluted tubule segment 1 development http://purl.obolibrary.org/obo/GO_0035295 tube development The process whose specific outcome is the progression of the S1 portion of the proximal convoluted tubule over time, from its formation to the mature structure. The S1 portion is the initial portion of the proximal convoluted tubule and is responsible for avid reabsorption of water and solutes. http://purl.obolibrary.org/obo/UBERON_0004800 bronchus basal lamina http://purl.obolibrary.org/obo/UBERON_0004799 trachea basal lamina A basal lamina that is part of a bronchus [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072032 proximal convoluted tubule segment 2 development http://purl.obolibrary.org/obo/GO_0035295 tube development The process whose specific outcome is the progression of the S2 portion of the proximal convoluted tubule over time, from its formation to the mature structure. The S2 portion of the tubule is involved in reabsorption of water and sodium chloride. http://purl.obolibrary.org/obo/UBERON_0004801 cervix epithelium http://purl.obolibrary.org/obo/UBERON_0006955 uterine epithelium An epithelium that is part of a uterine cervix [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072033 renal vesicle formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The developmental process pertaining to the initial formation of the renal vesicle from condensed mesenchymal cells. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells. http://purl.obolibrary.org/obo/UBERON_0004802 respiratory tract epithelium http://purl.obolibrary.org/obo/UBERON_0010499 pseudostratified ciliated columnar epithelium The pseudostratified ciliated epithelium that lines much of the conducting portion of the airway, including part of the nasal cavity and larynx, the trachea, and bronchi. http://purl.obolibrary.org/obo/GO_0072038 mesenchymal stem cell maintenance involved in nephron morphogenesis http://purl.obolibrary.org/obo/GO_0035019 somatic stem cell population maintenance The process in which an organism retains a population of mesenchymal stem cells that contributes to the shaping of a nephron. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells. http://purl.obolibrary.org/obo/UBERON_0004803 penis epithelium http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure An epithelium that is part of a penis [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072040 negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis http://purl.obolibrary.org/obo/GO_2001054 negative regulation of mesenchymal cell apoptotic process Any process that reduces the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron. http://purl.obolibrary.org/obo/UBERON_0004804 oviduct epithelium http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure An epithelium that is part of a oviduct [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004805 seminal vesicle epithelium http://purl.obolibrary.org/obo/UBERON_0034969 epithelial layer of duct An epithelium that is part of a seminal vesicle [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072044 collecting duct development http://purl.obolibrary.org/obo/GO_0035295 tube development The process whose specific outcome is the progression of a collecting duct over time, from its formation to the mature structure. The collecting duct responds to vasopressin and aldosterone to regulate water, electrolyte and acid-base balance. It is the final common path through which urine flows before entering the ureter and then emptying into the bladder. http://purl.obolibrary.org/obo/UBERON_0004806 vas deferens epithelium http://purl.obolibrary.org/obo/UBERON_0034969 epithelial layer of duct An epithelium that is part of a vas deferens [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072048 renal system pattern specification http://purl.obolibrary.org/obo/GO_0007389 pattern specification process Any developmental process that results in the creation of defined areas or spaces within an organism to which cells respond and eventually are instructed to differentiate into the anatomical structures of the renal system. http://purl.obolibrary.org/obo/UBERON_0004807 respiratory system epithelium http://purl.obolibrary.org/obo/UBERON_0000483 epithelium An epithelium that is part of a respiratory system [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072049 comma-shaped body morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the comma-shaped body is generated and organized. The comma-shaped body is the precursor structure to the S-shaped body that contributes to the morphogenesis of the nephron. http://purl.obolibrary.org/obo/UBERON_0004808 gastrointestinal system epithelium http://purl.obolibrary.org/obo/UBERON_0000483 epithelium An epithelium that is part of a digestive system [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072050 S-shaped body morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the S-shaped body is generated and organized. The S-shaped body is the successor of the comma-shaped body that contributes to the morphogenesis of the nephron. http://purl.obolibrary.org/obo/UBERON_0004809 salivary gland epithelium http://purl.obolibrary.org/obo/UBERON_0003929 digestive tract epithelium An epithelium that is part of a salivary gland [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072051 juxtaglomerular apparatus development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the juxtaglomerular apparatus over time, from its formation to the mature structure. The juxtaglomerular apparatus is an anatomical structure that lies adjacent to the glomerulus and regulates kidney function. http://purl.obolibrary.org/obo/UBERON_0004810 nephron tubule epithelium http://purl.obolibrary.org/obo/UBERON_0004211 nephron epithelium The cellular avascular layer of the renal tubule luminar surfaces. http://purl.obolibrary.org/obo/GO_0072052 juxtaglomerulus cell differentiation http://purl.obolibrary.org/obo/GO_0061005 cell differentiation involved in kidney development The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the juxtaglomerulus cells of the kidney as it progresses from its formation to the mature state. http://purl.obolibrary.org/obo/UBERON_0004811 endometrium epithelium http://purl.obolibrary.org/obo/UBERON_0006955 uterine epithelium An epithelium that is part of an endometrium [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072053 renal inner medulla development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the renal inner medulla over time, from its formation to the mature structure. The renal inner medulla is unique to mammalian kidneys and is the innermost region of the mammalian kidney. http://purl.obolibrary.org/obo/UBERON_0004812 male prepuce epithelium http://purl.obolibrary.org/obo/UBERON_0004803 penis epithelium An epithelium that is part of a prepuce of penis [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072054 renal outer medulla development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the renal outer medulla over time, from its formation to the mature structure. The renal outer medulla is the region of the kidney that lies between the renal cortex and the renal inner medulla. http://purl.obolibrary.org/obo/UBERON_0004813 seminiferous tubule epithelium http://purl.obolibrary.org/obo/UBERON_0034969 epithelial layer of duct The stratified epithelial lining of the seminiferous tubules, consisting of the developing spermatozoa and the supporting Sertoli cells, which are tall, columnar type cells that line the tubule. http://purl.obolibrary.org/obo/GO_0072055 renal cortex development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the renal cortex over time, from its formation to the mature structure. The renal cortex is the outer region of the kidney. http://purl.obolibrary.org/obo/UBERON_0004814 upper respiratory tract epithelium http://purl.obolibrary.org/obo/UBERON_0004802 respiratory tract epithelium An epithelium that is part of a upper respiratory tract [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072056 pyramid development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the kidney pyramids over time, from its formation to the mature structure. Kidney pyramids are the conical masses that constitute the renal medulla in a multi-lobed mammalian kidney; they contain the loops of Henle and the medullary collecting ducts. http://purl.obolibrary.org/obo/UBERON_0004815 lower respiratory tract epithelium http://purl.obolibrary.org/obo/UBERON_0004802 respiratory tract epithelium An epithelium that is part of a lower respiratory tract [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072057 inner stripe development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the inner stripe over time, from its formation to the mature structure. The inner stripe is a deep, centrally located portion of the renal outer medulla and is traversed by thin descending and thick ascending portions of the loops of Henle. http://purl.obolibrary.org/obo/UBERON_0004816 larynx epithelium http://purl.obolibrary.org/obo/UBERON_0004802 respiratory tract epithelium An epithelium that is part of a larynx [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072058 outer stripe development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the outer stripe over time, from its formation to the mature structure. The outer stripe is the region of the kidney outer medulla that lies just below the cortex. The proximal straight tubules (S3) characterize this region. http://purl.obolibrary.org/obo/UBERON_0004817 lacrimal gland epithelium http://purl.obolibrary.org/obo/UBERON_0015808 eye epithelium An epithelium that is part of a lacrimal gland [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072059 cortical collecting duct development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the cortical collecting duct over time, from its formation to the mature structure. The cortical collecting duct is the portion of the collecting duct that resides in the renal cortex. http://purl.obolibrary.org/obo/UBERON_0004819 kidney epithelium http://purl.obolibrary.org/obo/UBERON_0000483 epithelium The cellular avascular layer of the kidney luminar surfaces. http://purl.obolibrary.org/obo/GO_0072060 outer medullary collecting duct development http://purl.obolibrary.org/obo/GO_0072044 collecting duct development The process whose specific outcome is the progression of the outer medullary collecting duct over time, from its formation to the mature structure. The outer medullary collecting duct is the portion of the collecting duct that lies in the renal outer medulla. http://purl.obolibrary.org/obo/UBERON_0004820 bile duct epithelium http://purl.obolibrary.org/obo/UBERON_0034969 epithelial layer of duct Any epithelium that lines one of the bile ducts. http://purl.obolibrary.org/obo/GO_0072061 inner medullary collecting duct development http://purl.obolibrary.org/obo/GO_0072044 collecting duct development The process whose specific outcome is the progression of the inner medullary collecting duct over time, from its formation to the mature structure. The inner medullary collecting duct is the portion of the collecting duct that lies in the renal inner medulla. http://purl.obolibrary.org/obo/UBERON_0004821 pulmonary alveolus epithelium http://purl.obolibrary.org/obo/UBERON_0000487 simple squamous epithelium The epithelial layer of the alveoli[MP]. The layer of cells covering the lining of the tiny air sacs at the end of the bronchioles[BTO]. http://purl.obolibrary.org/obo/GO_0072063 short descending thin limb development http://purl.obolibrary.org/obo/GO_0072022 descending thin limb development The process whose specific outcome is the progression of the short descending thin limb over time, from its formation to the mature structure. The short descending thin limb is the descending thin limb of a short nephron that has a squamous epithelial morphology. http://purl.obolibrary.org/obo/UBERON_0004822 extrahepatic bile duct epithelium http://purl.obolibrary.org/obo/UBERON_0004820 bile duct epithelium An epithelium that is part of a extrahepatic bile duct [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072064 long descending thin limb development http://purl.obolibrary.org/obo/GO_0072022 descending thin limb development The process whose specific outcome is the progression of the long descending thin limb over time, from its formation to the mature structure. The long descending thin limb is the descending thin limb of a long nephron that has a squamous epithelial morphology. The long descending limb starts in the inner stripe of the outer medulla and extends into the inner medulla. http://purl.obolibrary.org/obo/UBERON_0004823 intrahepatic bile duct epithelium http://purl.obolibrary.org/obo/UBERON_0004820 bile duct epithelium An epithelium that is part of a intrahepatic bile duct [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072067 early distal convoluted tubule development http://purl.obolibrary.org/obo/GO_0072009 nephron epithelium development The process whose specific outcome is the progression of the early distal convoluted tubule over time, from its formation to the mature structure. The early distal convoluted tubule contains DCT cells and is vasopressin-insensitive. http://purl.obolibrary.org/obo/UBERON_0004827 thyroid gland medulla http://purl.obolibrary.org/obo/UBERON_0000958 medulla of organ A medulla that is part of a thyroid [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072068 late distal convoluted tubule development http://purl.obolibrary.org/obo/GO_0072009 nephron epithelium development The process whose specific outcome is the progression of the late distal convoluted tubule over time, from its formation to the mature structure. The late distal convoluted tubule contains DCT cells and intercalated (IC) alpha and beta cells and is vasopressin-sensitive. http://purl.obolibrary.org/obo/UBERON_0004829 urethra skeletal muscle tissue http://purl.obolibrary.org/obo/UBERON_0001134 skeletal muscle tissue A portion of skeletal muscle tissue that is part of a urethra [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072070 loop of Henle development http://purl.obolibrary.org/obo/GO_0072080 nephron tubule development The process whose specific outcome is the progression of the loop of Henle over time, from its formation to the mature structure. The loop of Henle is a nephron tubule that connects the proximal convoluted tubule to the distal convoluted tubule. http://purl.obolibrary.org/obo/UBERON_0004830 respiratory system skeletal muscle http://purl.obolibrary.org/obo/UBERON_0001134 skeletal muscle tissue A portion of skeletal muscle tissue that is part of a respiratory system [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072071 kidney interstitial fibroblast differentiation http://purl.obolibrary.org/obo/GO_0061005 cell differentiation involved in kidney development The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the interstitial fibroblast of the kidney as it progresses from its formation to the mature state. http://purl.obolibrary.org/obo/UBERON_0004831 esophagus skeletal muscle http://purl.obolibrary.org/obo/UBERON_0001134 skeletal muscle tissue A portion of skeletal muscle tissue that is part of a esophagus [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072073 kidney epithelium development http://purl.obolibrary.org/obo/GO_0060429 epithelium development The process whose specific outcome is the progression of an epithelium in the kidney over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. http://purl.obolibrary.org/obo/UBERON_0004832 anal region skeletal muscle http://purl.obolibrary.org/obo/UBERON_0001134 skeletal muscle tissue A portion of skeletal muscle tissue that is part of an anal region [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072074 kidney mesenchyme development http://purl.obolibrary.org/obo/GO_0060485 mesenchyme development The biological process whose specific outcome is the progression of a kidney mesenchyme from an initial condition to its mature state. This process begins with the formation of kidney mesenchyme and ends with the mature structure. Kidney mesenchyme is the tissue made up of loosely connected mesenchymal cells in the kidney. http://purl.obolibrary.org/obo/UBERON_0004833 lip skeletal muscle http://purl.obolibrary.org/obo/UBERON_0001134 skeletal muscle tissue A portion of skeletal muscle tissue that is part of a lip [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072075 metanephric mesenchyme development http://purl.obolibrary.org/obo/GO_0072074 kidney mesenchyme development The biological process whose specific outcome is the progression of a metanephric mesenchyme from an initial condition to its mature state. This process begins with the formation of metanephric mesenchyme and ends with the mature structure. Metanephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the metanephros. http://purl.obolibrary.org/obo/UBERON_0004834 hepatic duct smooth muscle http://purl.obolibrary.org/obo/UBERON_0001135 smooth muscle tissue Smooth muscle tissue in all or part of a hepatic duct. http://purl.obolibrary.org/obo/GO_0072076 nephrogenic mesenchyme development http://purl.obolibrary.org/obo/GO_0072074 kidney mesenchyme development The biological process whose specific outcome is the progression of a nephrogenic mesenchyme from an initial condition to its mature state. This process begins with the formation of nephrogenic mesenchyme and ends with the mature structure. Nephrogenic mesenchyme is the tissue made up of loosely connected mesenchymal cells in the nephron. http://purl.obolibrary.org/obo/UBERON_0004835 epididymis smooth muscle http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure A portion of smooth muscle tissue that is part of a epididymis [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072077 renal vesicle morphogenesis http://purl.obolibrary.org/obo/GO_0002009 morphogenesis of an epithelium The process in which the anatomical structures of the renal vesicle are generated and organized. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells. http://purl.obolibrary.org/obo/UBERON_0004848 respiratory system arterial endothelium http://purl.obolibrary.org/obo/UBERON_0004702 respiratory system blood vessel endothelium An endothelium of artery that is part of a respiratory system [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072087 renal vesicle development http://purl.obolibrary.org/obo/GO_0072073 kidney epithelium development The process whose specific outcome is the progression of the renal vesicle over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells. http://purl.obolibrary.org/obo/UBERON_0004849 respiratory system venous endothelium http://purl.obolibrary.org/obo/UBERON_0004702 respiratory system blood vessel endothelium An endothelium of vein that is part of a respiratory system [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072088 nephron epithelium morphogenesis http://purl.obolibrary.org/obo/GO_0002009 morphogenesis of an epithelium The process in which the anatomical structures of the nephron epithelium are generated and organized. The nephron epithelium is a tissue that covers the surface of a nephron. http://purl.obolibrary.org/obo/UBERON_0004850 lymph node endothelium http://purl.obolibrary.org/obo/UBERON_0001986 endothelium An endothelium that is part of a lymph node [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072091 regulation of stem cell proliferation http://purl.obolibrary.org/obo/GO_0042127 regulation of cell population proliferation Any process that modulates the frequency, rate or extent of stem cell proliferation. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells. http://purl.obolibrary.org/obo/UBERON_0004851 aorta endothelium http://purl.obolibrary.org/obo/UBERON_0004700 arterial system endothelium The thin layer of flat cells that line the aorta and form a barrier between circulating blood in the lumen and the rest of the vessel wall. http://purl.obolibrary.org/obo/GO_0072093 metanephric renal vesicle formation http://purl.obolibrary.org/obo/GO_0072033 renal vesicle formation The developmental process pertaining to the initial formation of the metanephros. http://purl.obolibrary.org/obo/UBERON_0004852 cardiovascular system endothelium http://purl.obolibrary.org/obo/UBERON_0001986 endothelium An endothelium that is part of the cardiovascular system. http://purl.obolibrary.org/obo/GO_0072099 anterior/posterior pattern specification involved in ureteric bud development http://purl.obolibrary.org/obo/GO_0009952 anterior/posterior pattern specification The developmental process that results in the creation of defined areas or spaces within the ureteric bud along the anterior/posterior axis to which cells respond and eventually are instructed to differentiate. http://purl.obolibrary.org/obo/UBERON_0004854 gastrointestinal system mesentery http://purl.obolibrary.org/obo/UBERON_0004782 gastrointestinal system serosa A mesentery that is part of a digestive system [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072103 glomerulus vasculature morphogenesis http://purl.obolibrary.org/obo/GO_0061439 kidney vasculature morphogenesis The process in which the anatomical structures of the glomerulus vasculature are generated and organized. The glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the glomerulus. http://purl.obolibrary.org/obo/UBERON_0004857 skeletal muscle connective tissue http://purl.obolibrary.org/obo/UBERON_0002384 connective tissue A connective tissue that surrounds a skeletal muscle tissue. http://purl.obolibrary.org/obo/GO_0072104 glomerular capillary formation http://purl.obolibrary.org/obo/GO_0001525 angiogenesis The process that gives rise to a glomerular capillary. This process pertains to the initial formation of a structure from unspecified parts. http://purl.obolibrary.org/obo/UBERON_0004859 eye gland http://purl.obolibrary.org/obo/UBERON_0002530 gland A gland that is part of a eye. The eye is a compound unit which depending on the species may consist of an eyeballs plus associated ducts and integumentary structures. Eye glands therefore include the various types of lacrimal gland, the various types of apocrine and sebaceous glands associated with the eyelid. http://purl.obolibrary.org/obo/GO_0072105 ureteric peristalsis http://purl.obolibrary.org/obo/GO_0014849 ureter smooth muscle contraction A wavelike sequence of involuntary muscular contraction and relaxation that passes along the ureter, impelling the contents onwards. The ureter is one of a pair of thick-walled tubes that transports urine from the kidney pelvis to the urinary bladder. http://purl.obolibrary.org/obo/UBERON_0004861 right lung alveolus http://purl.obolibrary.org/obo/UBERON_0002299 alveolus of lung An alveolus that is part of a right lung [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072106 regulation of ureteric bud formation http://purl.obolibrary.org/obo/GO_1905276 regulation of epithelial tube formation Any process that modulates the developmental process pertaining to the initial formation of the ureteric bud from the Wolffian duct. http://purl.obolibrary.org/obo/UBERON_0004862 left lung alveolus http://purl.obolibrary.org/obo/UBERON_0002299 alveolus of lung An alveolus that is part of a left lung [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004863 thoracic sympathetic nerve trunk http://purl.obolibrary.org/obo/UBERON_0004295 sympathetic nerve trunk A sympathetic nerve trunk that is part of a thorax [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072107 positive regulation of ureteric bud formation http://purl.obolibrary.org/obo/GO_1905278 positive regulation of epithelial tube formation Any process that increases the rate or extent of the developmental process pertaining to the initial formation of the ureteric bud from the Wolffian duct. http://purl.obolibrary.org/obo/UBERON_0004864 vasculature of retina http://purl.obolibrary.org/obo/UBERON_0036302 vasculature of central nervous system plus retina A vasculature that is part of a retina [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072108 positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis http://purl.obolibrary.org/obo/GO_1905332 positive regulation of morphogenesis of an epithelium Any process that increases the rate, frequency or extent of the transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros. http://purl.obolibrary.org/obo/UBERON_0004867 orbital cavity http://purl.obolibrary.org/obo/UBERON_0002553 anatomical cavity Anatomical cavity bounded by the orbital region of the cranium and forming the location of some or all of the eye. http://purl.obolibrary.org/obo/GO_0072109 glomerular mesangium development http://purl.obolibrary.org/obo/GO_0061448 connective tissue development The process whose specific outcome is the progression of the glomerular mesangium over time, from its formation to the mature structure. The glomerular mesangium is the thin membrane connective tissue composed of mesangial cells, which helps to support the capillary loops in a renal glomerulus. http://purl.obolibrary.org/obo/UBERON_0004871 somatic layer of lateral plate mesoderm http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure Layer of lateral plate mesoderm that forms the future body wall - underlies the ectoderm[WP]. http://purl.obolibrary.org/obo/GO_0072112 podocyte differentiation http://purl.obolibrary.org/obo/GO_0072311 glomerular epithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a glomerular visceral epithelial cell. A glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells. http://purl.obolibrary.org/obo/UBERON_0004872 splanchnic layer of lateral plate mesoderm http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure Layer of lateral plate mesoderm that forms the circulatory system and future gut wall - overlies endoderm[WP]. http://purl.obolibrary.org/obo/GO_0072120 pronephros maturation http://purl.obolibrary.org/obo/GO_0048799 animal organ maturation A developmental process, independent of morphogenetic (shape) change, that is required for the pronephros to attain its fully functional state. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life. http://purl.obolibrary.org/obo/UBERON_0004873 splanchnopleure http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure A structure created during embryogenesis when the lateral mesoderm splits into two layers - the inner (or splanchnic) layer adheres to the endoderm, and with it forms the splanchnopleure[WP]. http://purl.obolibrary.org/obo/GO_0072127 renal capsule development http://purl.obolibrary.org/obo/GO_0061448 connective tissue development The process whose specific outcome is the progression of the renal capsule over time, from its formation to the mature structure. The renal capsule is the tough fibrous layer surrounding the kidney, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. During development, it comprises a single layer of flattened cells that lie just above the cortical stroma and the condensed mesenchyme of the nephrogenic zone. It is in this region that the early stages of nephron induction and formation of new generations ureteric bud branches occur, as the kidney expands. http://purl.obolibrary.org/obo/UBERON_0004874 somatopleure http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure A structure created during embryogenesis when the lateral mesoderm splits into two layers - the outer (or somatic) layer becomes applied to the inner surface of the ectoderm, and with it forms the somatopleure.[WP]. http://purl.obolibrary.org/obo/GO_0072128 renal capsule morphogenesis http://purl.obolibrary.org/obo/GO_0048729 tissue morphogenesis The process in which the anatomical structures of the renal capsule are generated and organized. The renal capsule is the tough fibrous layer surrounding the kidney, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. During development, it comprises a single layer of flattened cells that lie just above the cortical stroma and the condensed mesenchyme of the nephrogenic zone. It is in this region that the early stages of nephron induction and formation of new generations ureteric bud branches occur, as the kidney expands. http://purl.obolibrary.org/obo/UBERON_0004875 nephrogenic cord http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure A portion of the urogenital ridge which is the source of much of the urinary system[WP]. http://purl.obolibrary.org/obo/GO_0072129 renal capsule formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The developmental process pertaining to the initial formation of a renal capsule from unspecified parts. The renal capsule is the tough fibrous layer surrounding the kidney, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. During development, it comprises a single layer of flattened cells that lie just above the cortical stroma and the condensed mesenchyme of the nephrogenic zone. It is in this region that the early stages of nephron induction and formation of new generations ureteric bud branches occur, as the kidney expands. http://purl.obolibrary.org/obo/UBERON_0004876 urogenital fold http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure One of of the pair of folds derived from the cloacal folds which give rise to a portion of the external genitalia; in male embryos they close over the urethral plate and fuse to form the spongy (penile) urethra and ventral aspect of the penis, not including the glans; failure of fusion of the urethral folds leads to hypospadias; in female embryos they fuse only anterior to the anus and form the labia minora[MP]. http://purl.obolibrary.org/obo/GO_0072131 kidney mesenchyme morphogenesis http://purl.obolibrary.org/obo/GO_0072132 mesenchyme morphogenesis The process in which the anatomical structures of a kidney mesenchymal tissue are generated and organized. Kidney mesenchyme is the tissue made up of loosely connected mesenchymal cells in the kidney. http://purl.obolibrary.org/obo/UBERON_0004877 visceral endoderm http://purl.obolibrary.org/obo/UBERON_0005292 extraembryonic tissue Visceral endoderm, a population of extraembyonic endoderm, is an extraembryonic tissue that functions in a regulatory capacity but does not contribute directly to the formation of any adult organs[PMID:15905405]. primitive endoderm-derived tissue which remains in contact with and surrounds the extra-embryonic ectoderm and the epiblast and provides signals for the differentiation and patterning of the epiblast; a small number of visceral endoderm cells also contribute to the endoderm of the embryonic gut[MP]. http://purl.obolibrary.org/obo/GO_0072133 metanephric mesenchyme morphogenesis http://purl.obolibrary.org/obo/GO_0072131 kidney mesenchyme morphogenesis The process in which the anatomical structures of a metanephric mesenchymal tissue are generated and organized. Metanephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the metanephros. http://purl.obolibrary.org/obo/UBERON_0004880 chordamesoderm http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure The central region of trunk mesoderm. This tissue forms the notochord. http://purl.obolibrary.org/obo/GO_0072134 nephrogenic mesenchyme morphogenesis http://purl.obolibrary.org/obo/GO_0072131 kidney mesenchyme morphogenesis The process in which the anatomical structures of a nephrogenic mesenchymal tissue are generated and organized. Nephrogenic mesenchyme is the tissue made up of loosely connected mesenchymal cells in the nephron. http://purl.obolibrary.org/obo/UBERON_0004883 lung mesenchyme http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure The mass of tissue made up of mesenchymal cells in the lung. http://purl.obolibrary.org/obo/GO_0072138 mesenchymal cell proliferation involved in ureteric bud development http://purl.obolibrary.org/obo/GO_0072111 cell proliferation involved in kidney development The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population of the ureteric bud, that contributes to ureteric bud development. http://purl.obolibrary.org/obo/UBERON_0004884 lobar bronchus mesenchyme http://purl.obolibrary.org/obo/UBERON_0004883 lung mesenchyme The mass of tissue composed of mesenchymal cells in the lobar bronchus.. http://purl.obolibrary.org/obo/GO_0072139 glomerular parietal epithelial cell differentiation http://purl.obolibrary.org/obo/GO_0072311 glomerular epithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a glomerular parietal epithelial cell. Glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. http://purl.obolibrary.org/obo/UBERON_0004889 lobar bronchus vasculature http://purl.obolibrary.org/obo/UBERON_0000102 lung vasculature Vasculature that is composed of the tubule structures that carry blood or lymph in the lungs. http://purl.obolibrary.org/obo/UBERON_0004893 interalveolar septum http://purl.obolibrary.org/obo/UBERON_0003037 septum A the thin septum that separates adjacent pulmonary alveoli, containing connective tissue constituents of the respiratory tissue and the capillary network of the blood supply of the lung. http://purl.obolibrary.org/obo/UBERON_0004894 alveolar wall http://purl.obolibrary.org/obo/UBERON_0000060 anatomical wall A wall that contains the alveoli. http://purl.obolibrary.org/obo/GO_0072141 renal interstitial fibroblast development http://purl.obolibrary.org/obo/GO_0048468 cell development The process whose specific outcome is the progression of a renal interstitial fibroblast over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/UBERON_0004895 alveolar smooth muscle http://purl.obolibrary.org/obo/UBERON_0004233 lower respiratory tract smooth muscle Alveolar smooth muscle is a type of non-striated muscle, found within the walls of the alveolus. http://purl.obolibrary.org/obo/GO_0072142 juxtaglomerulus cell development http://purl.obolibrary.org/obo/GO_0048468 cell development The process whose specific outcome is the progression of a juxtaglomerulus cell over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/UBERON_0004901 right lung lobar bronchus mesenchyme http://purl.obolibrary.org/obo/UBERON_0009603 right lung associated mesenchyme The right lung lobar bronchus mesenchyme is a type of tissue made up of loosely-packed mesenchymal cells in the right lung lobar bronchus. http://purl.obolibrary.org/obo/GO_0072143 mesangial cell development http://purl.obolibrary.org/obo/GO_0048468 cell development The process whose specific outcome is the progression of a mesangial cell in the kidney over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/UBERON_0004902 urogenital sinus epithelium http://purl.obolibrary.org/obo/UBERON_0009846 embryonic cloacal epithelium The fetal urogenital sinus (from which the prostate derives) is a simple cylinder of stratified basal epithelium, surrounded by mesenchyme and positioned between the embryonic bladder and pelvic urethra. http://purl.obolibrary.org/obo/GO_0072144 glomerular mesangial cell development http://purl.obolibrary.org/obo/GO_0072143 mesangial cell development The process whose specific outcome is the progression of a glomerular mesangial cell in the kidney over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/UBERON_0004903 bronchoalveolar duct junction http://purl.obolibrary.org/obo/UBERON_0007651 anatomical junction A branch point connecting the respiratory bronchioles to the alveolar ducts[MP]. http://purl.obolibrary.org/obo/GO_0072161 mesenchymal cell differentiation involved in kidney development http://purl.obolibrary.org/obo/GO_0061005 cell differentiation involved in kidney development The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the kidney as it progresses from its formation to the mature state. http://purl.obolibrary.org/obo/UBERON_0004904 neuron projection bundle connecting eye with brain http://purl.obolibrary.org/obo/UBERON_0000122 neuron projection bundle A neuron projection bundle that connects the retina or its analog in the eye with the brain. This includes the vertebrate optic nerve (not truly a nerve) as well as analogous structures such as the Bolwig nerve in Drosophila. http://purl.obolibrary.org/obo/GO_0072163 mesonephric epithelium development http://purl.obolibrary.org/obo/GO_0072073 kidney epithelium development The process whose specific outcome is the progression of an epithelium in the mesonephros over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. http://purl.obolibrary.org/obo/UBERON_0004905 articulation http://purl.obolibrary.org/obo/UBERON_0034921 multi organ part structure Anatomical structure that connects two or more adjacent skeletal elements or hardened body parts. http://purl.obolibrary.org/obo/GO_0072170 metanephric tubule development http://purl.obolibrary.org/obo/GO_0072207 metanephric epithelium development The progression of a metanephric tubule over time, from its initial formation to the mature structure. A metanephric tubule is an epithelial tube that is part of the metanephros. http://purl.obolibrary.org/obo/UBERON_0004906 ectodermal part of digestive tract http://purl.obolibrary.org/obo/UBERON_0004921 subdivision of digestive tract A portion of the gut that is derived from ectoderm. http://purl.obolibrary.org/obo/GO_0072171 mesonephric tubule morphogenesis http://purl.obolibrary.org/obo/GO_0072078 nephron tubule morphogenesis The process in which the anatomical structures of a mesonephric tubule are generated and organized. A mesonephric tubule is an epithelial tube that is part of the mesonephros. http://purl.obolibrary.org/obo/UBERON_0004907 lower digestive tract http://purl.obolibrary.org/obo/UBERON_0004921 subdivision of digestive tract The region of the digestive tract extending from the beginning of the intestines to the anus[GO - gut definition]. http://purl.obolibrary.org/obo/GO_0072172 mesonephric tubule formation http://purl.obolibrary.org/obo/GO_0072079 nephron tubule formation The developmental process pertaining to the initial formation of a mesonephric tubule from unspecified parts. A mesonephric tubule is an epithelial tube that is part of the mesonephros. http://purl.obolibrary.org/obo/UBERON_0004908 upper digestive tract http://purl.obolibrary.org/obo/UBERON_0004921 subdivision of digestive tract The region of the digestive tract extending from the mouth cavity through pharynx esophagus stomach and duodenum. http://purl.obolibrary.org/obo/GO_0072173 metanephric tubule morphogenesis http://purl.obolibrary.org/obo/GO_0060562 epithelial tube morphogenesis The process in which the anatomical structures of a metanephric tubule are generated and organized from an epithelium. A metanephric tubule is an epithelial tube that is part of the metanephros. http://purl.obolibrary.org/obo/UBERON_0004909 epithelium of gonad http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure An epithelium surrounding a gonad. http://purl.obolibrary.org/obo/GO_0072174 metanephric tubule formation http://purl.obolibrary.org/obo/GO_0072175 epithelial tube formation The developmental process pertaining to the initial formation of a metanephric tubule. http://purl.obolibrary.org/obo/UBERON_0004910 epithelium of male gonad http://purl.obolibrary.org/obo/UBERON_0004909 epithelium of gonad An epithelium surrounding a testis. http://purl.obolibrary.org/obo/GO_0072177 mesonephric duct development http://purl.obolibrary.org/obo/GO_0072176 nephric duct development The process whose specific outcome is the progression of a mesonephric duct over time, from its initial formation to a mature structure. A mesonephric duct is a tube drains the mesonephros. http://purl.obolibrary.org/obo/UBERON_0004911 epithelium of female gonad http://purl.obolibrary.org/obo/UBERON_0004909 epithelium of gonad An epithelium surrounding an ovary. http://purl.obolibrary.org/obo/GO_0072179 nephric duct formation http://purl.obolibrary.org/obo/GO_0072175 epithelial tube formation The developmental process pertaining to the initial formation of a nephric duct. A nephric duct is a tube that drains a primitive kidney. http://purl.obolibrary.org/obo/UBERON_0004914 duodenal papilla http://purl.obolibrary.org/obo/UBERON_0034944 zone of organ One of the two small elevations on the mucosa of the duodenum, the major at the entrance of the conjoined pancreatic and common bile ducts and the minor at the entrance of the accessory pancreatic duct. http://purl.obolibrary.org/obo/GO_0072180 mesonephric duct morphogenesis http://purl.obolibrary.org/obo/GO_0072171 mesonephric tubule morphogenesis The process in which the anatomical structures of the mesonephric duct are generated and organized. A mesonephric duct is a tube drains the mesonephros. http://purl.obolibrary.org/obo/UBERON_0004915 sphincter of hepatopancreatic ampulla http://purl.obolibrary.org/obo/UBERON_0011185 gastrointestinal sphincter Muscular valve that controls the flow of digestive juices (bile and pancreatic juice) through the ampulla of Vater into the second part of the duodenum. Relaxed by the hormone Cholecystokinin (CCK) via vasoactive intestinal polypeptide (VIP).[WP]. http://purl.obolibrary.org/obo/GO_0072181 mesonephric duct formation http://purl.obolibrary.org/obo/GO_0072180 mesonephric duct morphogenesis The developmental process pertaining to the initial formation of a mesonephric duct. A mesonephric duct is a tube that drains the mesonephros. http://purl.obolibrary.org/obo/UBERON_0004916 anal sphincter http://purl.obolibrary.org/obo/UBERON_0004590 sphincter muscle A sphincter muscle that is part of a anal region. http://purl.obolibrary.org/obo/GO_0072182 regulation of nephron tubule epithelial cell differentiation http://purl.obolibrary.org/obo/GO_2000696 regulation of epithelial cell differentiation involved in kidney development Any process that modulates the frequency, rate or extent of nephron tubule epithelial cell differentiation. http://purl.obolibrary.org/obo/UBERON_0004917 urethral sphincter http://purl.obolibrary.org/obo/UBERON_0004590 sphincter muscle A sphincter muscle surrounding the urethra. http://purl.obolibrary.org/obo/GO_0072183 negative regulation of nephron tubule epithelial cell differentiation http://purl.obolibrary.org/obo/GO_0090185 negative regulation of kidney development Any process that decreases the frequency, rate or extent of nephron tubule epithelial cell differentiation. http://purl.obolibrary.org/obo/UBERON_0004921 subdivision of digestive tract http://purl.obolibrary.org/obo/UBERON_0013522 subdivision of tube A proximal-distal subdivision of the digestive tract. http://purl.obolibrary.org/obo/GO_0072190 ureter urothelium development http://purl.obolibrary.org/obo/GO_0060429 epithelium development The process whose specific outcome is the progression of the urothelium of the ureter over time, from its formation to the mature structure. The urothelium is an epithelium that makes up the epithelial tube of the ureter. http://purl.obolibrary.org/obo/UBERON_0004923 organ component layer http://purl.obolibrary.org/obo/UBERON_0000064 organ part A part of a wall of an organ that forms a layer. http://purl.obolibrary.org/obo/GO_0072191 ureter smooth muscle development http://purl.obolibrary.org/obo/GO_0048745 smooth muscle tissue development The process whose specific outcome is the progression of smooth muscle in the ureter over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/UBERON_0004924 submucosa of pharynx http://purl.obolibrary.org/obo/UBERON_0018257 submucosa of digestive tract The tissue underlying the tunica mucosa of the pharynx. http://purl.obolibrary.org/obo/GO_0072193 ureter smooth muscle cell differentiation http://purl.obolibrary.org/obo/GO_0051145 smooth muscle cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell in the ureter. http://purl.obolibrary.org/obo/UBERON_0004926 submucosa of cystic duct http://purl.obolibrary.org/obo/UBERON_0004938 submucosa of biliary tree A submucosa that is part of a cystic duct [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072194 kidney smooth muscle tissue development http://purl.obolibrary.org/obo/GO_0048745 smooth muscle tissue development The process whose specific outcome is the progression of smooth muscle in the kidney over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/UBERON_0004927 submucosa of cecum http://purl.obolibrary.org/obo/UBERON_0003331 submucosa of colon A submucosa that is part of a cecum [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072198 mesenchymal cell proliferation involved in ureter development http://purl.obolibrary.org/obo/GO_0010463 mesenchymal cell proliferation The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population of the ureter, that contributes to ureter development. http://purl.obolibrary.org/obo/UBERON_0004928 submucosa of appendix http://purl.obolibrary.org/obo/UBERON_0001208 submucosa of large intestine A submucosa that is part of an appendix [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004929 submucosa of ascending colon http://purl.obolibrary.org/obo/UBERON_0003331 submucosa of colon A submucosa that is part of an ascending colon [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072200 negative regulation of mesenchymal cell proliferation involved in ureter development http://purl.obolibrary.org/obo/GO_0072201 negative regulation of mesenchymal cell proliferation Any process that decreases the frequency, rate or extent of mesenchymal cell proliferation that contributes to the progression of the ureter gland over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets. http://purl.obolibrary.org/obo/UBERON_0004930 submucosa of transverse colon http://purl.obolibrary.org/obo/UBERON_0003331 submucosa of colon A submucosa that is part of a transverse colon [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072201 negative regulation of mesenchymal cell proliferation http://purl.obolibrary.org/obo/GO_0008285 negative regulation of cell population proliferation Any process that decreases the frequency, rate or extent of mesenchymal cell proliferation. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets. http://purl.obolibrary.org/obo/UBERON_0004931 submucosa of descending colon http://purl.obolibrary.org/obo/UBERON_0003331 submucosa of colon A submucosa that is part of a descending colon [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072203 cell proliferation involved in metanephros development http://purl.obolibrary.org/obo/GO_0072111 cell proliferation involved in kidney development The multiplication or reproduction of cells, resulting in the expansion of the population in the metanephros. http://purl.obolibrary.org/obo/UBERON_0004932 submucosa of sigmoid colon http://purl.obolibrary.org/obo/UBERON_0003331 submucosa of colon A submucosa that is part of a sigmoid colon [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072205 metanephric collecting duct development http://purl.obolibrary.org/obo/GO_0072044 collecting duct development The process whose specific outcome is the progression of a collecting duct in the metanephros over time, from its formation to the mature structure. The collecting duct responds to vasopressin and aldosterone to regulate water, electrolyte and acid-base balance. The collecting duct is the final common path through which urine flows before entering the ureter and then emptying into the bladder. http://purl.obolibrary.org/obo/UBERON_0004933 submucosa of fundus of stomach http://purl.obolibrary.org/obo/UBERON_0001200 submucosa of stomach A submucosa that is part of a fundus of stomach [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072206 metanephric juxtaglomerular apparatus development http://purl.obolibrary.org/obo/GO_0072051 juxtaglomerular apparatus development The process whose specific outcome is the progression of the juxtaglomerular apparatus in the metanephros over time, from its formation to the mature structure. The juxtaglomerular apparatus is an anatomical structure which consists of juxtaglomerular cells, extraglomerular mesangial cells and the macula densa. The juxtaglomerular apparatus lies adjacent to the glomerulus and regulates kidney function by maintaining the blood flow to the kidney and the filtration rate. http://purl.obolibrary.org/obo/UBERON_0004934 submucosa of body of stomach http://purl.obolibrary.org/obo/UBERON_0001200 submucosa of stomach A submucosa that is part of a body of stomach [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072207 metanephric epithelium development http://purl.obolibrary.org/obo/GO_0072073 kidney epithelium development The process whose specific outcome is the progression of an epithelium in the metanephros over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. http://purl.obolibrary.org/obo/UBERON_0004935 submucosa of cardia of stomach http://purl.obolibrary.org/obo/UBERON_0001200 submucosa of stomach A submucosa that is part of a cardia of stomach [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072208 metanephric smooth muscle tissue development http://purl.obolibrary.org/obo/GO_0072194 kidney smooth muscle tissue development The process whose specific outcome is the progression of smooth muscle in the metanephros over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/UBERON_0004936 submucosa of pyloric antrum http://purl.obolibrary.org/obo/UBERON_0004937 submucosa of pylorus A submucosa that is part of a pyloric antrum [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072210 metanephric nephron development http://purl.obolibrary.org/obo/GO_0072006 nephron development The process whose specific outcome is the progression of a nephron in the metanephros over time, from its formation to the mature structure. A nephron is the functional unit of the kidney. http://purl.obolibrary.org/obo/UBERON_0004937 submucosa of pylorus http://purl.obolibrary.org/obo/UBERON_0001200 submucosa of stomach A submucosa that is part of a pylorus [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072211 metanephric pyramids development http://purl.obolibrary.org/obo/GO_0072056 pyramid development The process whose specific outcome is the progression of the metanephric pyramids over time, from their formation to the mature structures. Metanephric pyramids are the conical masses that constitute the renal medulla in a metanephros; they contain the loops of Henle and the medullary collecting ducts. http://purl.obolibrary.org/obo/UBERON_0004938 submucosa of biliary tree http://purl.obolibrary.org/obo/UBERON_0000009 submucosa A submucosa that is part of a biliary tree [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072213 metanephric capsule development http://purl.obolibrary.org/obo/GO_0072127 renal capsule development The process whose specific outcome is the progression of the metanephric capsule over time, from its formation to the mature structure. The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. http://purl.obolibrary.org/obo/UBERON_0004939 submucosa of common bile duct http://purl.obolibrary.org/obo/UBERON_0004938 submucosa of biliary tree A submucosa that is part of a common bile duct [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072214 metanephric cortex development http://purl.obolibrary.org/obo/GO_0072055 renal cortex development The process whose specific outcome is the progression of the metanephric cortex over time, from its formation to the mature structure. The metanephric cortex is the outer region of the metanephros. http://purl.obolibrary.org/obo/UBERON_0004940 submucosa of common hepatic duct http://purl.obolibrary.org/obo/UBERON_0004938 submucosa of biliary tree A submucosa that is part of a common hepatic duct [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072216 positive regulation of metanephros development http://purl.obolibrary.org/obo/GO_0090184 positive regulation of kidney development Any process that increases the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine. http://purl.obolibrary.org/obo/UBERON_0004941 submucosa of right hepatic duct http://purl.obolibrary.org/obo/UBERON_0004938 submucosa of biliary tree A submucosa that is part of a right hepatic duct [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072218 metanephric ascending thin limb development http://purl.obolibrary.org/obo/GO_0072234 metanephric nephron tubule development The process whose specific outcome is the progression of a metanephric ascending thin limb over time, from its formation to the mature structure. The metanephric ascending thin limb is a segment of a nephron tubule in the metanephros lying in the inner medulla that is permeable to ions but not to water and has a simple epithelium; active transepithelial solute transport is absent. http://purl.obolibrary.org/obo/UBERON_0004942 submucosa of left hepatic duct http://purl.obolibrary.org/obo/UBERON_0004938 submucosa of biliary tree A submucosa that is part of a left hepatic duct [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072219 metanephric cortical collecting duct development http://purl.obolibrary.org/obo/GO_0072059 cortical collecting duct development The process whose specific outcome is the progression of the metanephric cortical collecting duct over time, from its formation to the mature structure. The metanephric cortical collecting duct is the portion of the metanephric collecting duct that resides in the renal cortex. http://purl.obolibrary.org/obo/UBERON_0004943 submucosa of urinary bladder http://purl.obolibrary.org/obo/UBERON_0000009 submucosa The submucous layer of the wall of the urinary bladder. http://purl.obolibrary.org/obo/GO_0072220 metanephric descending thin limb development http://purl.obolibrary.org/obo/GO_0072022 descending thin limb development The process whose specific outcome is the progression of the metanephric descending thin limb over time, from its formation to the mature structure. The metanephric descending thin limb is a part of the metanephric loop of Henle situated just after the proximal straight tubule (S3). It extends to the tip of the metanephric loop of Henle. http://purl.obolibrary.org/obo/UBERON_0004944 submucosa of trigone of urinary bladder http://purl.obolibrary.org/obo/UBERON_0004943 submucosa of urinary bladder A submucosa that is part of a trigone of urinary bladder [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004945 submucosa of neck of urinary bladder http://purl.obolibrary.org/obo/UBERON_0004943 submucosa of urinary bladder A submucosa that is part of a neck of urinary bladder [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072221 metanephric distal convoluted tubule development http://purl.obolibrary.org/obo/GO_0072234 metanephric nephron tubule development The process whose specific outcome is the progression of the metanephric distal convoluted tubule over time, from its formation to the mature structure. The metanephric distal convoluted tubule is the first segment of the metanephric nephron lying just downstream from the loop of Henle, immediately after the macula densa. Among other functions, in humans it is responsible for the reabsorption of about 5% of filtered sodium via the thiazide-sensitive Na-Cl symporter. http://purl.obolibrary.org/obo/UBERON_0004946 submucosa of ileum http://purl.obolibrary.org/obo/UBERON_0001205 submucosa of small intestine A submucosa that is part of a ileum [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004950 submucosa of lobar bronchus http://purl.obolibrary.org/obo/UBERON_0001957 submucosa of bronchus A submucosa that is part of a lobar bronchus [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072222 metanephric early distal convoluted tubule development http://purl.obolibrary.org/obo/GO_0072243 metanephric nephron epithelium development The process whose specific outcome is the progression of the metanephric early distal convoluted tubule over time, from its formation to the mature structure. The metanephric early distal convoluted tubule contains metanephric DCT cells and is vasopressin-insensitive. http://purl.obolibrary.org/obo/UBERON_0004951 submucosa of segmental bronchus http://purl.obolibrary.org/obo/UBERON_0001957 submucosa of bronchus A submucosa that is part of a segmental bronchus [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072223 metanephric glomerular mesangium development http://purl.obolibrary.org/obo/GO_0072109 glomerular mesangium development The process whose specific outcome is the progression of the metanephric glomerular mesangium over time, from its formation to the mature structure. The metanephric glomerular mesangium is the thin membrane connective tissue composed of mesangial cells in the metanephros, which helps to support the capillary loops in a renal glomerulus. http://purl.obolibrary.org/obo/UBERON_0004952 submucosa of bronchiole http://purl.obolibrary.org/obo/UBERON_0004777 respiratory system submucosa A submucosa that is part of a bronchiole [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072224 metanephric glomerulus development http://purl.obolibrary.org/obo/GO_0032835 glomerulus development The progression of the metanephric glomerulus over time from its initial formation until its mature state. The metanephric glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the mature vertebrate kidney, or metanephros. http://purl.obolibrary.org/obo/UBERON_0004980 mucosa of ureter http://purl.obolibrary.org/obo/UBERON_0000344 mucosa A mucosa that is part of a ureter [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072225 metanephric late distal convoluted tubule development http://purl.obolibrary.org/obo/GO_0072243 metanephric nephron epithelium development The process whose specific outcome is the progression of the metanephric late distal convoluted tubule over time, from its formation to the mature structure. The metanephric late distal convoluted tubule contains metanephric DCT cells and intercalated (IC) alpha and beta cells and is vasopressin-sensitive. http://purl.obolibrary.org/obo/UBERON_0004983 mucosa of vagina http://purl.obolibrary.org/obo/UBERON_0019042 reproductive system mucosa A mucosa that is part of a vagina [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004984 mucosa of seminal vesicle http://purl.obolibrary.org/obo/UBERON_0019042 reproductive system mucosa A mucosa that is part of a seminal vesicle [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072227 metanephric macula densa development http://purl.obolibrary.org/obo/GO_0072243 metanephric nephron epithelium development The process whose specific outcome is the progression of the metanephric macula densa over time, from its formation to the mature structure. The metanephric macula densa is an area of specialized cells in the distal tubule of the metanephros that makes contact with the vascular pole of the glomerulus. http://purl.obolibrary.org/obo/UBERON_0004985 mucosa of ejaculatory duct http://purl.obolibrary.org/obo/UBERON_0019042 reproductive system mucosa A mucosa that is part of a ejaculatory duct [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072229 metanephric proximal convoluted tubule development http://purl.obolibrary.org/obo/GO_0072234 metanephric nephron tubule development The process whose specific outcome is the progression of the metanephric proximal convoluted tubule over time, from its formation to the mature structure. The metanephric proximal convoluted tubule is the most proximal portion of the metanephric proximal tubule and extends from the metanephric glomerular capsule to the metanephric proximal straight tubule. http://purl.obolibrary.org/obo/UBERON_0004986 mucosa of deferent duct http://purl.obolibrary.org/obo/UBERON_0019042 reproductive system mucosa A mucosa that is part of a vas deferens [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072230 metanephric proximal straight tubule development http://purl.obolibrary.org/obo/GO_0072234 metanephric nephron tubule development The process whose specific outcome is the progression of the metanephric proximal straight tubule over time, from its formation to the mature structure. The metanephric proximal straight tubule is the part of the metanephric descending limb that extends from the metanephric proximal convoluted tubule to the metanephric descending thin tubule. http://purl.obolibrary.org/obo/UBERON_0004988 mucosa of cystic duct http://purl.obolibrary.org/obo/UBERON_0004999 mucosa of biliary tree A mucosa that is part of a cystic duct [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072231 metanephric proximal convoluted tubule segment 1 development http://purl.obolibrary.org/obo/GO_0072031 proximal convoluted tubule segment 1 development The process whose specific outcome is the progression of the S1 portion of the metanephric proximal convoluted tubule over time, from its formation to the mature structure. The S1 portion is the initial portion of the metanephric proximal convoluted tubule and is responsible for avid reabsorption of water and solutes. http://purl.obolibrary.org/obo/UBERON_0004989 mucosa of appendix http://purl.obolibrary.org/obo/UBERON_0001207 mucosa of large intestine A mucosa that is part of an appendix [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072233 metanephric thick ascending limb development http://purl.obolibrary.org/obo/GO_0072234 metanephric nephron tubule development The process whose specific outcome is the progression of the metanephric thick ascending limb over time, from its formation to the mature structure. The metanephric thick ascending limb is the last part of the metanephric loop of Henle. Its thick, mitochondria-rich epithelium characterizes the outer medulla, and is responsible for very avid active salt transport. At the macula densa, the thick ascending limb connects to the distal convoluted tubule. http://purl.obolibrary.org/obo/UBERON_0004990 mucosa of ascending colon http://purl.obolibrary.org/obo/UBERON_0000317 colonic mucosa A mucosa that is part of an ascending colon [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072234 metanephric nephron tubule development http://purl.obolibrary.org/obo/GO_0072243 metanephric nephron epithelium development The progression of a metanephric nephron tubule over time, from its initial formation to the mature structure. A metanephric nephron tubule is an epithelial tube that is part of the metanephric nephron, the functional part of the metanephros. http://purl.obolibrary.org/obo/UBERON_0004991 mucosa of transverse colon http://purl.obolibrary.org/obo/UBERON_0000317 colonic mucosa A mucosa that is part of a transverse colon [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072235 metanephric distal tubule development http://purl.obolibrary.org/obo/GO_0072234 metanephric nephron tubule development The process whose specific outcome is the progression of the metanephric distal tubule over time, from its formation to the mature structure. The metanephric distal tubule is a metanephric nephron tubule that begins at the metanephric macula densa and extends to the metanephric connecting tubule. http://purl.obolibrary.org/obo/UBERON_0004992 mucosa of descending colon http://purl.obolibrary.org/obo/UBERON_0000317 colonic mucosa A mucosa that is part of a descending colon [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072236 metanephric loop of Henle development http://purl.obolibrary.org/obo/GO_0072234 metanephric nephron tubule development The process whose specific outcome is the progression of the metanephric loop of Henle over time, from its formation to the mature structure. The metanephric loop of Henle is a metanephric nephron tubule that connects the proximal convoluted tubule to the distal convoluted tubule in the metanephros. http://purl.obolibrary.org/obo/UBERON_0004993 mucosa of sigmoid colon http://purl.obolibrary.org/obo/UBERON_0000317 colonic mucosa A mucosa that is part of a sigmoid colon [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072237 metanephric proximal tubule development http://purl.obolibrary.org/obo/GO_0072234 metanephric nephron tubule development The process whose specific outcome is the progression of the metanephric proximal tubule over time, from its formation to the mature structure. The metanephric proximal tubule is a metanephric nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle in the metanephros. It has a brush border epithelial morphology. http://purl.obolibrary.org/obo/UBERON_0004994 mucosa of fundus of stomach http://purl.obolibrary.org/obo/UBERON_0001199 mucosa of stomach A mucosa that is part of a fundus of stomach [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072238 metanephric long nephron development http://purl.obolibrary.org/obo/GO_0072210 metanephric nephron development The process whose specific outcome is the progression of a metanephric long nephron over time, from its formation to the mature structure. Long nephrons are associated with juxtamedullary glomeruli and extend into the inner medulla in the metanephros. http://purl.obolibrary.org/obo/UBERON_0004995 mucosa of body of stomach http://purl.obolibrary.org/obo/UBERON_0001199 mucosa of stomach A mucosa that is part of a body of stomach [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072239 metanephric glomerulus vasculature development http://purl.obolibrary.org/obo/GO_0072012 glomerulus vasculature development The biological process whose specific outcome is the progression of a metanephric glomerulus vasculature from an initial condition to its mature state. This process begins with the formation of the metanephric glomerulus vasculature and ends with the mature structure. The metanephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the metanephric glomerulus. http://purl.obolibrary.org/obo/UBERON_0004996 mucosa of cardia of stomach http://purl.obolibrary.org/obo/UBERON_0001199 mucosa of stomach A mucosa that is part of a cardia of stomach [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072243 metanephric nephron epithelium development http://purl.obolibrary.org/obo/GO_0072207 metanephric epithelium development The process whose specific outcome is the progression of the metanephric nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The metanephric nephron epithelium is a tissue that covers the surface of a nephron in the metanephros. http://purl.obolibrary.org/obo/UBERON_0004997 mucosa of pyloric antrum http://purl.obolibrary.org/obo/UBERON_0004998 mucosa of pylorus A mucosa that is part of a pyloric antrum [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004998 mucosa of pylorus http://purl.obolibrary.org/obo/UBERON_0001199 mucosa of stomach A mucosa that is part of a pylorus [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072244 metanephric glomerular epithelium development http://purl.obolibrary.org/obo/GO_0072243 metanephric nephron epithelium development The process whose specific outcome is the progression of the metanephric glomerular epithelium over time, from its formation to the mature structure. The metanephric glomerular epithelium is an epithelial tissue that covers the outer surfaces of the glomerulus in the metanephros. The metanephric glomerular epithelium consists of both parietal and visceral epithelium. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros. http://purl.obolibrary.org/obo/UBERON_0004999 mucosa of biliary tree http://purl.obolibrary.org/obo/UBERON_0000344 mucosa A mucosa that is part of a biliary tree [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072248 metanephric podocyte differentiation http://purl.obolibrary.org/obo/GO_0072312 metanephric glomerular epithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a metanephric glomerular visceral epithelial cell. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros. http://purl.obolibrary.org/obo/UBERON_0005000 mucosa of common bile duct http://purl.obolibrary.org/obo/UBERON_0004999 mucosa of biliary tree A mucosa that is part of a common bile duct [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072249 metanephric podocyte development http://purl.obolibrary.org/obo/GO_0072313 metanephric glomerular epithelial cell development The process whose specific outcome is the progression of a metanephric glomerular visceral epithelial cell over time, from its formation to the mature structure. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros. http://purl.obolibrary.org/obo/UBERON_0005001 mucosa of common hepatic duct http://purl.obolibrary.org/obo/UBERON_0004999 mucosa of biliary tree A mucosa that is part of a common hepatic duct [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072257 metanephric nephron tubule epithelial cell differentiation http://purl.obolibrary.org/obo/GO_0072160 nephron tubule epithelial cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the metanephric nephron tubule as it progresses from its formation to the mature state. http://purl.obolibrary.org/obo/UBERON_0005002 mucosa of right hepatic duct http://purl.obolibrary.org/obo/UBERON_0004999 mucosa of biliary tree A mucosa that is part of a right hepatic duct [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0005003 mucosa of left hepatic duct http://purl.obolibrary.org/obo/UBERON_0004999 mucosa of biliary tree A mucosa that is part of a left hepatic duct [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072264 metanephric glomerular endothelium development http://purl.obolibrary.org/obo/GO_0072244 metanephric glomerular epithelium development The process whose specific outcome is the progression of the metanephric glomerular endothelium over time, from its formation to the mature structure. The metanephric glomerular endothelium is an epithelial tissue that covers the internal surfaces of the glomerulus of the metanephros. http://purl.obolibrary.org/obo/UBERON_0005004 mucosa of right ureter http://purl.obolibrary.org/obo/UBERON_0004980 mucosa of ureter A mucosa that is part of a right ureter [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072265 metanephric capsule morphogenesis http://purl.obolibrary.org/obo/GO_0072128 renal capsule morphogenesis The process in which the anatomical structures of the metanephric capsule are generated and organized. The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. http://purl.obolibrary.org/obo/UBERON_0005005 mucosa of left ureter http://purl.obolibrary.org/obo/UBERON_0004980 mucosa of ureter A mucosa that is part of a left ureter [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072266 metanephric capsule formation http://purl.obolibrary.org/obo/GO_0072129 renal capsule formation The developmental process pertaining to the initial formation of a metanephric capsule from unspecified parts. The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. http://purl.obolibrary.org/obo/UBERON_0005006 mucosa of renal pelvis http://purl.obolibrary.org/obo/UBERON_0000344 mucosa A mucosa that is part of a renal pelvis [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0005009 mucosa of trigone of urinary bladder http://purl.obolibrary.org/obo/UBERON_0001259 mucosa of urinary bladder A mucosa that is part of a trigone of urinary bladder [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072268 pattern specification involved in metanephros development http://purl.obolibrary.org/obo/GO_0007389 pattern specification process Any developmental process that results in the creation of defined areas or spaces within the metanephros to which cells respond and eventually are instructed to differentiate. http://purl.obolibrary.org/obo/UBERON_0005010 mucosa of neck of urinary bladder http://purl.obolibrary.org/obo/UBERON_0001259 mucosa of urinary bladder A mucosa that is part of a neck of urinary bladder [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072269 metanephric long descending thin limb development http://purl.obolibrary.org/obo/GO_0072243 metanephric nephron epithelium development The process whose specific outcome is the progression of the metanephric long descending thin limb over time, from its formation to the mature structure. The metanephric long descending thin limb is the descending thin limb of a long nephron in the metanephros that has a squamous epithelial morphology. The long descending limb starts in the inner stripe of the outer medulla and extends into the inner medulla. http://purl.obolibrary.org/obo/UBERON_0005011 mucosa of right fallopian tube http://purl.obolibrary.org/obo/UBERON_0005048 mucosa of fallopian tube A mucosa that is part of a right uterine tube [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0005012 mucosa of left fallopian tube http://purl.obolibrary.org/obo/UBERON_0005048 mucosa of fallopian tube A mucosa that is part of a left uterine tube [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072270 metanephric short nephron development http://purl.obolibrary.org/obo/GO_0072210 metanephric nephron development The process whose specific outcome is the progression of a short nephron in the metanephros over time, from its formation to the mature structure. Short nephrons are associated with mid-cortical and superficial glomeruli, are situated entirely in the outer medulla, and have no thin ascending limb. http://purl.obolibrary.org/obo/UBERON_0005013 mucosa of male urethra http://purl.obolibrary.org/obo/UBERON_0012299 mucosa of urethra A mucosa that is part of a male urethra [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072271 metanephric short descending thin limb development http://purl.obolibrary.org/obo/GO_0072243 metanephric nephron epithelium development The process whose specific outcome is the progression of the metanephric short descending thin limb over time, from its formation to the mature structure. The metanephric short descending thin limb is the descending thin limb of a short nephron in the metanephros that has a squamous epithelial morphology. http://purl.obolibrary.org/obo/UBERON_0005014 mucosa of female urethra http://purl.obolibrary.org/obo/UBERON_0012299 mucosa of urethra A mucosa that is part of a female urethra [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072273 metanephric nephron morphogenesis http://purl.obolibrary.org/obo/GO_0072028 nephron morphogenesis The process in which the anatomical structures of the metanephric nephron are generated and organized. A metanephric nephron is the functional unit of the metanephros. http://purl.obolibrary.org/obo/UBERON_0005015 mucosa of prostatic urethra http://purl.obolibrary.org/obo/UBERON_0005013 mucosa of male urethra A mucosa that is part of a prostatic urethra [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072275 metanephric glomerulus morphogenesis http://purl.obolibrary.org/obo/GO_0072102 glomerulus morphogenesis The process in which the anatomical structures of the metanephric glomerulus are generated and organized. The metanephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney, or metanephros. http://purl.obolibrary.org/obo/UBERON_0005017 mucosa of lacrimal sac http://purl.obolibrary.org/obo/UBERON_0005043 mucosa of nasolacrimal duct A mucosa that is part of a lacrimal sac [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072276 metanephric glomerulus vasculature morphogenesis http://purl.obolibrary.org/obo/GO_0072103 glomerulus vasculature morphogenesis The process in which the anatomical structures of the metanephric glomerulus vasculature are generated and organized. The metanephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the metanephric glomerulus. http://purl.obolibrary.org/obo/UBERON_0005020 mucosa of tongue http://purl.obolibrary.org/obo/UBERON_0003729 mouth mucosa A mucosa that is part of a tongue [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072277 metanephric glomerular capillary formation http://purl.obolibrary.org/obo/GO_0072104 glomerular capillary formation The process that gives rise to a metanephric glomerular capillary. This process pertains to the initial formation of a structure from unspecified parts. http://purl.obolibrary.org/obo/UBERON_0005022 mucosa of nasopharynx http://purl.obolibrary.org/obo/UBERON_0000355 pharyngeal mucosa A mucosa that is part of a nasopharynx [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072278 metanephric comma-shaped body morphogenesis http://purl.obolibrary.org/obo/GO_0072049 comma-shaped body morphogenesis The process in which the metanephric comma-shaped body is generated and organized. The metanephric comma-shaped body is the precursor structure to the metanephric S-shaped body that contributes to the morphogenesis of a nephron in the metanephros. http://purl.obolibrary.org/obo/UBERON_0005026 mucosa of middle ear http://purl.obolibrary.org/obo/UBERON_0000344 mucosa A mucosa that is part of a middle ear [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072282 metanephric nephron tubule morphogenesis http://purl.obolibrary.org/obo/GO_0072173 metanephric tubule morphogenesis The process in which the anatomical structures of a metanephric nephron tubule are generated and organized. A metanephric nephron tubule is an epithelial tube that is part of the metanephric nephron, the functional part of the metanephros. http://purl.obolibrary.org/obo/UBERON_0005029 mucosa of lacrimal canaliculus http://purl.obolibrary.org/obo/UBERON_0000344 mucosa A mucosa that is part of a lacrimal canaliculus [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072284 metanephric S-shaped body morphogenesis http://purl.obolibrary.org/obo/GO_0072050 S-shaped body morphogenesis The process in which the metanephric S-shaped body is generated and organized. The metanephric S-shaped body is the successor of the metanephric comma-shaped body that contributes to the morphogenesis of a nephron in the metanephros. http://purl.obolibrary.org/obo/UBERON_0005031 mucosa of upper lip http://purl.obolibrary.org/obo/UBERON_0036294 mucosa of lip A mucosa that is part of a upper lip [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0005032 mucosa of lower lip http://purl.obolibrary.org/obo/UBERON_0036294 mucosa of lip A mucosa that is part of a lower lip [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072285 mesenchymal to epithelial transition involved in metanephric renal vesicle formation http://purl.obolibrary.org/obo/GO_0003337 mesenchymal to epithelial transition involved in metanephros morphogenesis A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephric renal vesicle. http://purl.obolibrary.org/obo/UBERON_0005033 mucosa of gallbladder http://purl.obolibrary.org/obo/UBERON_0000344 mucosa A mucosa that is part of a gallbladder [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072286 metanephric connecting tubule development http://purl.obolibrary.org/obo/GO_0072234 metanephric nephron tubule development The process whose specific outcome is the progression of the metanephric connecting tubule over time, from its formation to the mature structure. The metanephric connecting tubule is a tubular segment of the metanephric nephron; it connects the distal convoluted tubule to the collecting duct in the metanephros. http://purl.obolibrary.org/obo/UBERON_0005037 mucosa of lobar bronchus http://purl.obolibrary.org/obo/UBERON_0000410 bronchial mucosa A mucosa that is part of a lobar bronchus [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072287 metanephric distal tubule morphogenesis http://purl.obolibrary.org/obo/GO_0072282 metanephric nephron tubule morphogenesis The process in which the anatomical structures of a metanephric distal tubule are generated and organized. The metanephric distal tubule is a metanephric nephron tubule that begins at the macula densa and extends to the metanephric connecting tubule. http://purl.obolibrary.org/obo/UBERON_0005038 mucosa of segmental bronchus http://purl.obolibrary.org/obo/UBERON_0000410 bronchial mucosa A mucosa that is part of a segmental bronchus [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072288 metanephric proximal tubule morphogenesis http://purl.obolibrary.org/obo/GO_0072282 metanephric nephron tubule morphogenesis The process in which the anatomical structures of a metanephric proximal tubule are generated and organized. The metanephric proximal tubule is a metanephric nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle in the metanephros. It has a brush border epithelial morphology. http://purl.obolibrary.org/obo/UBERON_0005039 mucosa of bronchiole http://purl.obolibrary.org/obo/UBERON_0004785 respiratory system mucosa A mucosa that is part of a bronchiole [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072289 metanephric nephron tubule formation http://purl.obolibrary.org/obo/GO_0072174 metanephric tubule formation The developmental process pertaining to the initial formation of a metanephric nephron tubule from unspecified parts. A metanephric nephron tubule is an epithelial tube that is part of a nephron in the metanephros. http://purl.obolibrary.org/obo/UBERON_0005040 mucosa of terminal bronchiole http://purl.obolibrary.org/obo/UBERON_0005039 mucosa of bronchiole A mucosa that is part of a terminal bronchiole [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072298 regulation of metanephric glomerulus development http://purl.obolibrary.org/obo/GO_0090192 regulation of glomerulus development Any process that modulates the rate, frequency or extent of metanephric glomerulus development, the progression of the metanephric glomerulus over time from its initial formation until its mature state. The metanephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney, or metanephros. http://purl.obolibrary.org/obo/UBERON_0005041 mucosa of respiratory bronchiole http://purl.obolibrary.org/obo/UBERON_0005039 mucosa of bronchiole A mucosa that is part of a respiratory bronchiole [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072299 negative regulation of metanephric glomerulus development http://purl.obolibrary.org/obo/GO_0090194 negative regulation of glomerulus development Any process that decreases the rate, frequency or extent of metanephric glomerulus development, the progression of the metanephric glomerulus over time from its initial formation until its mature state. The metanephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney, or metanephros. http://purl.obolibrary.org/obo/UBERON_0005042 inner epithelial layer of tympanic membrane http://purl.obolibrary.org/obo/UBERON_0009647 tympanic membrane epithelium A portion of the tympanic cavity epithelium which makes up the outer (cuticular) layer of the tympanic membrane. http://purl.obolibrary.org/obo/UBERON_0005043 mucosa of nasolacrimal duct http://purl.obolibrary.org/obo/UBERON_0000344 mucosa A mucosa that is part of a nasolacrimal duct [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072300 positive regulation of metanephric glomerulus development http://purl.obolibrary.org/obo/GO_0090193 positive regulation of glomerulus development Any process that increases the rate, frequency or extent of metanephric glomerulus development, the progression of the metanephric glomerulus over time from its initial formation until its mature state. The metanephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney, or metanephros. http://purl.obolibrary.org/obo/UBERON_0005044 mucosa of pharyngotympanic tube http://purl.obolibrary.org/obo/UBERON_0005026 mucosa of middle ear A mucosa that is part of a pharyngotympanic tube [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0005048 mucosa of fallopian tube http://purl.obolibrary.org/obo/UBERON_0019042 reproductive system mucosa A mucosa that is part of a fallopian tube [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072307 regulation of metanephric nephron tubule epithelial cell differentiation http://purl.obolibrary.org/obo/GO_0072182 regulation of nephron tubule epithelial cell differentiation Any process that modulates the frequency, rate or extent of metanephric nephron tubule epithelial cell differentiation. http://purl.obolibrary.org/obo/UBERON_0005049 mucosa of infundibulum of uterine tube http://purl.obolibrary.org/obo/UBERON_0019042 reproductive system mucosa A mucosa that is part of a uterine tube infundibulum [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072308 negative regulation of metanephric nephron tubule epithelial cell differentiation http://purl.obolibrary.org/obo/GO_0072307 regulation of metanephric nephron tubule epithelial cell differentiation Any process that decreases the frequency, rate or extent of metanephric nephron tubule epithelial cell differentiation. http://purl.obolibrary.org/obo/UBERON_0005051 mediastinum testis http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure The mediastinum testis is a network of fibrous connective tissue that extends from the upper to near the lower extremity of the testis, and is wider above than below. From its front and sides numerous imperfect septa (trabeculæ) are given off, which radiate toward the surface of the organ, and are attached to the tunica albuginea. They divide the interior of the organ into a number of incomplete spaces, called lobules. These are somewhat cone-shaped, being broad at their bases at the surface of the gland, and becoming narrower as they converge to the mediastinum. The mediastinum supports the rete testis and blood vessels of the testis in their passage to and from the substance of the gland[WP]. http://purl.obolibrary.org/obo/GO_0072310 glomerular epithelial cell development http://purl.obolibrary.org/obo/GO_0002064 epithelial cell development The process whose specific outcome is the progression of a glomerular epithelial cell over time, from its formation to the mature structure. Glomerular epithelial cells are specialized epithelial cells that form part of the glomerulus; there are two types, glomerular parietal epithelial cells and glomerular visceral epithelial cells. http://purl.obolibrary.org/obo/UBERON_0005055 zone of long bone http://purl.obolibrary.org/obo/UBERON_0005913 zone of bone organ An organ part that is part of a long bone [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072311 glomerular epithelial cell differentiation http://purl.obolibrary.org/obo/GO_0035850 epithelial cell differentiation involved in kidney development The process in which a relatively unspecialized cell acquires specialized features of a glomerular epithelial cell. Glomerular epithelial cells are specialized epithelial cells that form part of the glomerulus; there are two types, glomerular parietal epithelial cells and glomerular visceral epithelial cells. http://purl.obolibrary.org/obo/UBERON_0005056 external female genitalia http://purl.obolibrary.org/obo/UBERON_0004176 external genitalia An external genitalia that is part of a female reproductive system [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0072312 metanephric glomerular epithelial cell differentiation http://purl.obolibrary.org/obo/GO_0072311 glomerular epithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a metanephric glomerular epithelial cell. Metanephric glomerular epithelial cells are specialized epithelial cells that form part of the metanephric glomerulus; there are two types, metanephric glomerular parietal epithelial cells and metanephric glomerular visceral epithelial cells. http://purl.obolibrary.org/obo/UBERON_0005058 hemolymphoid system gland http://purl.obolibrary.org/obo/UBERON_0002530 gland A gland that is part of a hemolymphoid system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0005061 neural groove http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure The median dorsal longitudinal groove formed in the embryo by the neural plate after the appearance of the neural folds. http://purl.obolibrary.org/obo/GO_0072313 metanephric glomerular epithelial cell development http://purl.obolibrary.org/obo/GO_0072310 glomerular epithelial cell development The process whose specific outcome is the progression of a metanephric glomerular epithelial cell over time, from its formation to the mature structure. Metanephric glomerular epithelial cells are specialized epithelial cells that form part of the metanephric glomerulus; there are two types, metanephric glomerular parietal epithelial cells and metanephric glomerular visceral epithelial cells. http://purl.obolibrary.org/obo/UBERON_0005062 neural fold http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure One of the two elevated edges of the neural groove[GO,MP]. http://purl.obolibrary.org/obo/GO_0072343 pancreatic stellate cell proliferation http://purl.obolibrary.org/obo/GO_0048144 fibroblast proliferation The multiplication or reproduction of pancreatic stellate cells, resulting in the expansion of a pancreatic stellate cell population. Pancreatic stellate cells are found in the periacinar space of the exocrine pancreas and in perivascular and periductal regions of the pancreas, and have long cytoplasmic processes that encircle the base of the acinus. http://purl.obolibrary.org/obo/UBERON_0005064 left ventricular trabecular myocardium http://purl.obolibrary.org/obo/UBERON_0004126 trabecular layer of ventricle Missing definition for term UBERON:0005064. Please replace it using linked reference. http://purl.obolibrary.org/obo/GO_0072360 vascular cord development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the vascular cord over time from its initial formation until its mature state. The vascular cord is the primordial vasculature that will develop into blood vessels by the process of tubulogenesis. http://purl.obolibrary.org/obo/UBERON_0005066 right ventricular trabecular myocardium http://purl.obolibrary.org/obo/UBERON_0004126 trabecular layer of ventricle Missing definition for term UBERON:0005066. Please replace it using linked reference. http://purl.obolibrary.org/obo/GO_0072520 seminiferous tubule development http://purl.obolibrary.org/obo/GO_0048608 reproductive structure development The reproductive developmental process whose specific outcome is the progression of the seminiferous tubule over time, from its formation to the mature structure. Seminiferous tubules are ducts located in the testicles, and are the specific location of meiosis, and the subsequent creation of gametes, namely spermatozoa. http://purl.obolibrary.org/obo/UBERON_0005068 neural rod http://purl.obolibrary.org/obo/UBERON_0016879 future central nervous system A solid rod of neurectoderm derived from the neural keel. The neural rod is roughly circular in cross section. Neural rod formation occurs during primary neurulation in teleosts[GO]. An intermediate stage in the development of the central nervous system present during the segmentation period; the neural rod is roughly cylindrical in shape, forms from the neural keel, and is not yet hollowed out into the neural tube[ZFIN]. http://purl.obolibrary.org/obo/GO_0072538 T-helper 17 type immune response http://purl.obolibrary.org/obo/GO_0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains An immune response which is associated with resistance to intracellular bacteria with a key role in inflammation and tissue injury. This immune response is associated with pathological autoimmune conditions such as multiple sclerosis, arthritis and psoriasis which is typically orchestrated by the production of particular cytokines by T-helper 17 cells, most notably interleukin-17, IL-21 and IL-22. http://purl.obolibrary.org/obo/UBERON_0005075 forebrain-midbrain boundary http://purl.obolibrary.org/obo/UBERON_0007651 anatomical junction An anatomical boundary that adjacent_to a forebrain and adjacent_to a midbrain. http://purl.obolibrary.org/obo/GO_0072539 T-helper 17 cell differentiation http://purl.obolibrary.org/obo/GO_0042093 T-helper cell differentiation The process in which a relatively unspecialized T cell acquires the specialized features of a T-helper 17 (Th17) cell. A Th17 cell is a CD4-positive, alpha-beta T cell with the phenotype RORgamma-t-positive that produces IL-17. http://purl.obolibrary.org/obo/UBERON_0005076 hindbrain-spinal cord boundary http://purl.obolibrary.org/obo/UBERON_0007651 anatomical junction An anatomical boundary that adjacent_to a hindbrain and adjacent_to a spinal cord. http://purl.obolibrary.org/obo/GO_0072553 terminal button organization http://purl.obolibrary.org/obo/GO_0099172 presynapse organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a terminal button. A terminal button is the terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters. http://purl.obolibrary.org/obo/UBERON_0005080 metanephric ureteric bud http://purl.obolibrary.org/obo/UBERON_0000084 ureteric bud The portion of the ureteric bud tube that contributes to the morphogenesis of the metanephros[GO]. http://purl.obolibrary.org/obo/GO_0072560 type B pancreatic cell maturation http://purl.obolibrary.org/obo/GO_0002070 epithelial cell maturation A developmental process, independent of morphogenetic (shape) change, that is required for a type B pancreatic cell to attain its fully functional state. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin. http://purl.obolibrary.org/obo/UBERON_0005081 ureter ureteric bud http://purl.obolibrary.org/obo/UBERON_0000084 ureteric bud The portion of the ureteric bud that contributes to the morphogenesis of the ureter. The ureter ureteric bud is the initial structure that forms the ureter[GO]. http://purl.obolibrary.org/obo/GO_0072574 hepatocyte proliferation http://purl.obolibrary.org/obo/GO_0050673 epithelial cell proliferation The multiplication or reproduction of hepatocytes, resulting in the expansion of a cell population. Hepatocytes form the main structural component of the liver. They are specialized epithelial cells that are organized into interconnected plates called lobules. http://purl.obolibrary.org/obo/UBERON_0005082 tube lumen http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space A hole in a tube[GO]. http://purl.obolibrary.org/obo/GO_0072576 liver morphogenesis http://purl.obolibrary.org/obo/GO_0022612 gland morphogenesis The process in which the anatomical structures of the liver are generated and organized. http://purl.obolibrary.org/obo/UBERON_0005085 ectodermal placode http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm[GO]. http://purl.obolibrary.org/obo/GO_0072577 endothelial cell apoptotic process http://purl.obolibrary.org/obo/GO_0006915 apoptotic process Any apoptotic process in an endothelial cell. An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal. http://purl.obolibrary.org/obo/UBERON_0005086 hair follicle placode http://purl.obolibrary.org/obo/UBERON_0011817 skin appendage placode A bud-like thickening in the epidermis consisting of elongated keratinocytes, which at the distal end are in touch with numerous aggregated specialized dermal fibroblasts, the dermal condensate. http://purl.obolibrary.org/obo/GO_0072592 oxygen metabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process The chemical reactions and pathways involving diatomic oxygen (O2). http://purl.obolibrary.org/obo/UBERON_0005087 tooth placode http://purl.obolibrary.org/obo/UBERON_0011814 non-neurogenic ectodermal placode An tooth placode is a thickening of the ectoderm that will give rise to the tooth bud[GO]. http://purl.obolibrary.org/obo/UBERON_0005088 sebaceous gland placode http://purl.obolibrary.org/obo/UBERON_0011814 non-neurogenic ectodermal placode A sebaceous gland placode is a thickening of the ectoderm that will give rise to the sebaceous gland bud[GO]. http://purl.obolibrary.org/obo/GO_0072597 maintenance of protein location in chloroplast http://purl.obolibrary.org/obo/GO_0072595 maintenance of protein localization in organelle Any process in which a protein is maintained in a specific location in a chloroplast, and is prevented from moving elsewhere. http://purl.obolibrary.org/obo/UBERON_0005089 sweat gland placode http://purl.obolibrary.org/obo/UBERON_0011814 non-neurogenic ectodermal placode An sweat gland placode is a thickening of the ectoderm that will give rise to the sweat gland bud[GO]. http://purl.obolibrary.org/obo/GO_0072598 protein localization to chloroplast http://purl.obolibrary.org/obo/GO_0033365 protein localization to organelle A process in which a protein is transported to, or maintained at, a location in a chloroplast. http://purl.obolibrary.org/obo/UBERON_0005090 muscle structure http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure Muscle structures are contractile cells, tissues or organs that are found in multicellular organisms[GO]. http://purl.obolibrary.org/obo/GO_0072656 maintenance of protein location in mitochondrion http://purl.obolibrary.org/obo/GO_0072595 maintenance of protein localization in organelle Any process in which a protein is maintained in a specific location in a mitochondrion, and is prevented from moving elsewhere. http://purl.obolibrary.org/obo/UBERON_0005095 kidney rudiment http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure Missing definition for term UBERON:0005095. Please replace it using linked reference. http://purl.obolibrary.org/obo/GO_0072665 protein localization to vacuole http://purl.obolibrary.org/obo/GO_0033365 protein localization to organelle A process in which a protein is transported to, or maintained at, a location in a vacuole. http://purl.obolibrary.org/obo/UBERON_0005096 descending thin limb http://purl.obolibrary.org/obo/UBERON_0000064 organ part The descending thin limb is a part of the loop of Henle situated just after the proximal straight tubule (S3). It extends to the tip of the loop of Henle[GO]. http://purl.obolibrary.org/obo/GO_0072667 maintenance of protein location in vacuole http://purl.obolibrary.org/obo/GO_0072595 maintenance of protein localization in organelle Any process in which a protein is maintained in a specific location in a vacuole, and is prevented from moving elsewhere. http://purl.obolibrary.org/obo/UBERON_0005097 renal connecting tubule http://purl.obolibrary.org/obo/UBERON_0012275 meso-epithelium The connecting tubule is a tubular segment of the nephron; it connects the distal convoluted tubule to the collecting duct[GO]. http://purl.obolibrary.org/obo/GO_0072674 multinuclear osteoclast differentiation http://purl.obolibrary.org/obo/GO_0030316 osteoclast differentiation The process in which a relatively unspecialized monocyte acquires the specialized features of a multinuclear osteoclast. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue. http://purl.obolibrary.org/obo/UBERON_0005099 short descending thin limb http://purl.obolibrary.org/obo/UBERON_0006914 squamous epithelium The short descending thin limb is the descending thin limb of a short nephron that has a squamous epithelial morphology[GO]. http://purl.obolibrary.org/obo/GO_0072679 thymocyte migration http://purl.obolibrary.org/obo/GO_0072678 T cell migration The movement of a thymocyte through distinct intrathymic niches (e.g. medulla, cortex), where it receives a unique set of developmental cues required for T-cell development. http://purl.obolibrary.org/obo/UBERON_0005100 long descending thin limb http://purl.obolibrary.org/obo/UBERON_0004211 nephron epithelium The long descending limb starts in the inner stripe of the outer medulla and extends into the inner medulla[GO]. http://purl.obolibrary.org/obo/GO_0075296 positive regulation of ascospore formation http://purl.obolibrary.org/obo/GO_0090068 positive regulation of cell cycle process Any process that activates, maintains or increases the frequency, rate or extent of ascospore formation, a process in which a sexual spore, named ascospore, from Ascomycete fungi was produced inside an ascus. http://purl.obolibrary.org/obo/UBERON_0005101 early distal convoluted tubule http://purl.obolibrary.org/obo/UBERON_0004211 nephron epithelium The early distal convoluted tubule contains DCT cells and is vasopressin-insensitive[GO]. http://purl.obolibrary.org/obo/GO_0075297 negative regulation of ascospore formation http://purl.obolibrary.org/obo/GO_0010948 negative regulation of cell cycle process Any process that stops, prevents, or reduces the frequency, rate or extent of ascospore formation, a process in which a sexual spore, named ascospore, from Ascomycete fungi was produced inside an ascus. http://purl.obolibrary.org/obo/UBERON_0005102 late distal convoluted tubule http://purl.obolibrary.org/obo/UBERON_0004211 nephron epithelium The late distal convoluted tubule contains DCT cells and intercalated (IC) alpha and beta cells and is vasopressin-sensitive[GO]. http://purl.obolibrary.org/obo/GO_0075298 regulation of zygospore formation http://purl.obolibrary.org/obo/GO_0043940 regulation of sexual sporulation resulting in formation of a cellular spore Any process that modulates the frequency, rate or extent of zygospore formation, a process in which a thick-walled spore of some algae and fungi is formed by union of two similar sexual cells, usually serves as a resting spore, and produces the sporophytic phase. http://purl.obolibrary.org/obo/UBERON_0005103 mesonephric epithelium http://purl.obolibrary.org/obo/UBERON_0004819 kidney epithelium An epithelium that is part of a mesonephros [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0075299 positive regulation of zygospore formation http://purl.obolibrary.org/obo/GO_0075298 regulation of zygospore formation Any process that activates, maintains or increases the frequency, rate or extent of frequency, rate or extent of zygospore formation, a process in which a thick-walled spore of some algae and fungi is formed by union of two similar sexual cells, usually serves as a resting spore, and produces the sporophytic phase. http://purl.obolibrary.org/obo/UBERON_0005106 metanephric tubule http://purl.obolibrary.org/obo/UBERON_0006555 excretory tube A metanephric tubule is an epithelial tube that is part of the metanephros[GO]. http://purl.obolibrary.org/obo/GO_0075300 negative regulation of zygospore formation http://purl.obolibrary.org/obo/GO_0075298 regulation of zygospore formation Any process that stops, prevents, or reduces the frequency, rate or extent of zygospore formation, a process in which a thick-walled spore of some algae and fungi is formed by union of two similar sexual cells, usually serves as a resting spore, and produces the sporophytic phase. http://purl.obolibrary.org/obo/UBERON_0005108 metanephric epithelium http://purl.obolibrary.org/obo/UBERON_0004819 kidney epithelium An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure[GO]. http://purl.obolibrary.org/obo/UBERON_0005109 metanephric smooth muscle tissue http://purl.obolibrary.org/obo/UBERON_0001135 smooth muscle tissue Any smooth muscle tissue that is part of a metanephros. http://purl.obolibrary.org/obo/GO_0075302 regulation of basidiospore formation http://purl.obolibrary.org/obo/GO_0043940 regulation of sexual sporulation resulting in formation of a cellular spore Any process that modulates the frequency, rate or extent of basidiospore formation, a process in which a sexually produced fungal spore is formed on a basidium in the fungi Basidiomycetes. http://purl.obolibrary.org/obo/UBERON_0005110 metanephric nephron http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure A metanephric nephron is the functional unit of the metanephros[GO]. http://purl.obolibrary.org/obo/GO_0075303 positive regulation of basidiospore formation http://purl.obolibrary.org/obo/GO_0075302 regulation of basidiospore formation Any process that activates, maintains or increases the frequency, rate or extent of frequency, rate or extent of basidiospore formation, a process in which a sexually produced fungal spore is formed on a basidium in the fungi basidiomycetes. http://purl.obolibrary.org/obo/UBERON_0005111 metanephric pyramid http://purl.obolibrary.org/obo/UBERON_0004200 kidney pyramid Metanephric pyramids are the conical masses that constitute the renal medulla in a metanephros; they contain the loops of Henle and the medullary collecting ducts[GO]. http://purl.obolibrary.org/obo/GO_0075304 negative regulation of basidiospore formation http://purl.obolibrary.org/obo/GO_0075302 regulation of basidiospore formation Any process that stops, prevents, or reduces the frequency, rate or extent of basidiospore formation, a process in which a sexually produced fungal spore is formed on a basidium in the fungi basidiomycetes. http://purl.obolibrary.org/obo/UBERON_0005114 metanephric ascending thin limb http://purl.obolibrary.org/obo/UBERON_0005146 metanephric nephron tubule The metanephric ascending thin limb is a segment of a nephron tubule in the metanephros lying in the inner medulla that is permeable to ions but not to water and has a simple epithelium; active transepithelial solute transport is absent[GO]. http://purl.obolibrary.org/obo/GO_0080144 intracellular amino acid homeostasis http://purl.obolibrary.org/obo/GO_0055082 intracellular chemical homeostasis A homeostatic process involved in the maintenance of a steady state level of amino acids within a cell. http://purl.obolibrary.org/obo/UBERON_0005115 metanephric cortical collecting duct http://purl.obolibrary.org/obo/UBERON_0004203 cortical collecting duct The metanephric cortical collecting duct is the portion of the metanephric collecting duct that resides in the renal cortex[GO]. http://purl.obolibrary.org/obo/GO_0086009 membrane repolarization http://purl.obolibrary.org/obo/GO_0042391 regulation of membrane potential The process in which ions are transported across a membrane such that the membrane potential changes in the repolarizing direction, toward the steady state potential. For example, the repolarization during an action potential is from a positive membrane potential towards a negative resting potential. http://purl.obolibrary.org/obo/UBERON_0005116 metanephric descending thin limb http://purl.obolibrary.org/obo/UBERON_0005096 descending thin limb It extends to the tip of the metanephric loop of Henle[GO]. http://purl.obolibrary.org/obo/GO_0090183 regulation of kidney development http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine. http://purl.obolibrary.org/obo/UBERON_0005117 metanephric distal convoluted tubule http://purl.obolibrary.org/obo/UBERON_0005146 metanephric nephron tubule The metanephric distal convoluted tubule is a portion of the metanephric nephron tubule that connects the metanephric loop of Henle to the collecting duct[GO]. http://purl.obolibrary.org/obo/GO_0090184 positive regulation of kidney development http://purl.obolibrary.org/obo/GO_0090183 regulation of kidney development Any process that increases the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine. http://purl.obolibrary.org/obo/UBERON_0005118 metanephric early distal convoluted tubule http://purl.obolibrary.org/obo/UBERON_0005134 metanephric nephron epithelium The metanephric early distal convoluted tubule contains metanephric DCT cells and is vasopressin-insensitive[GO]. http://purl.obolibrary.org/obo/GO_0090185 negative regulation of kidney development http://purl.obolibrary.org/obo/GO_0090183 regulation of kidney development Any process that decreases the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine. http://purl.obolibrary.org/obo/UBERON_0005119 metanephric glomerular mesangium http://purl.obolibrary.org/obo/UBERON_0002320 glomerular mesangium The metanephric glomerular mesangium is the thin membrane connective tissue composed of mesangial cells in the metanephros, which helps to support the capillary loops in a renal glomerulus[GO]. http://purl.obolibrary.org/obo/UBERON_0005120 metanephric late distal convoluted tubule http://purl.obolibrary.org/obo/UBERON_0005134 metanephric nephron epithelium The metanephric late distal convoluted tubule contains metanephric DCT cells and intercalated (IC) alpha and beta cells and is vasopressin-sensitive[GO]. http://purl.obolibrary.org/obo/GO_0090189 regulation of branching involved in ureteric bud morphogenesis http://purl.obolibrary.org/obo/GO_0090183 regulation of kidney development Any process that modulates the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules. http://purl.obolibrary.org/obo/UBERON_0005122 metanephric macula densa http://purl.obolibrary.org/obo/UBERON_0005134 metanephric nephron epithelium The metanephric macula densa is an area of specialized cells in the distal tubule of the metanephros that makes contact with the vascular pole of the glomerulus[GO]. http://purl.obolibrary.org/obo/GO_0090191 negative regulation of branching involved in ureteric bud morphogenesis http://purl.obolibrary.org/obo/GO_0090189 regulation of branching involved in ureteric bud morphogenesis Any process that decreases the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules. http://purl.obolibrary.org/obo/UBERON_0005124 metanephric proximal convoluted tubule http://purl.obolibrary.org/obo/UBERON_0005146 metanephric nephron tubule The metanephric proximal convoluted tubule is the most proximal portion of the metanephric proximal tubule and extends from the metanephric glomerular capsule to the metanephric proximal straight tubule[GO]. http://purl.obolibrary.org/obo/GO_0090192 regulation of glomerulus development http://purl.obolibrary.org/obo/GO_0090183 regulation of kidney development Any process that modulates the rate, frequency or extent of glomerulus development, the progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney. http://purl.obolibrary.org/obo/UBERON_0005125 metanephric proximal straight tubule http://purl.obolibrary.org/obo/UBERON_0005146 metanephric nephron tubule The metanephric proximal straight tubule is the part of the metanephric descending limb that extends from the metanephric proximal convoluted tubule to the metanephric descending thin tubule[GO]. http://purl.obolibrary.org/obo/GO_0090193 positive regulation of glomerulus development http://purl.obolibrary.org/obo/GO_0090192 regulation of glomerulus development Any process that increases the rate, frequency or extent of glomerulus development, the progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney. http://purl.obolibrary.org/obo/UBERON_0005126 metanephric S1 http://purl.obolibrary.org/obo/UBERON_0004196 proximal convoluted tubule segment 1 The S1 portion is the initial portion of the metanephric proximal convoluted tubule and is responsible for avid reabsorption of water and solutes[GO]. http://purl.obolibrary.org/obo/GO_0090194 negative regulation of glomerulus development http://purl.obolibrary.org/obo/GO_0090192 regulation of glomerulus development Any process that decreases the rate, frequency or extent of glomerulus development, the progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney. http://purl.obolibrary.org/obo/UBERON_0005127 metanephric thick ascending limb http://purl.obolibrary.org/obo/UBERON_0005146 metanephric nephron tubule At the macula densa, the thick ascending limb connects to the distal convoluted tubule[GO]. http://purl.obolibrary.org/obo/GO_0090214 spongiotrophoblast layer developmental growth http://purl.obolibrary.org/obo/GO_0048589 developmental growth The increase in size or mass of the spongiotrophoblast layer of the placenta where the increase in size or mass contributes to the progression of that layer over time from its formation to its mature state. http://purl.obolibrary.org/obo/UBERON_0005129 metanephric distal tubule http://purl.obolibrary.org/obo/UBERON_0005146 metanephric nephron tubule The metanephric distal tubule is a metanephric nephron tubule that begins at the metanephric macula densa and extends to the metanephric connecting tubule[GO]. http://purl.obolibrary.org/obo/GO_0090425 acinar cell differentiation http://purl.obolibrary.org/obo/GO_0002067 glandular epithelial cell differentiation The epithelial cell differentiation process in which a relatively unspecialized cell acquires specialized features of an acinar cell, a secretory cell that is grouped together with other cells of the same type to form grape-shaped clusters known as acini. http://purl.obolibrary.org/obo/UBERON_0005130 metanephric loop of Henle http://purl.obolibrary.org/obo/UBERON_0005146 metanephric nephron tubule The metanephric loop of Henle is a metanephric nephron tubule that connects the proximal convoluted tubule to the distal convoluted tubule in the metanephros[GO]. http://purl.obolibrary.org/obo/GO_0097084 vascular associated smooth muscle cell development http://purl.obolibrary.org/obo/GO_0055001 muscle cell development The process aimed at the progression of a vascular smooth muscle cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels. http://purl.obolibrary.org/obo/UBERON_0005132 metanephric long nephron http://purl.obolibrary.org/obo/UBERON_0005110 metanephric nephron Long nephrons are associated with juxtamedullary glomeruli and extend into the inner medulla in the metanephros[GO]. http://purl.obolibrary.org/obo/GO_0097094 craniofacial suture morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which any suture between cranial and/or facial bones is generated and organized. http://purl.obolibrary.org/obo/UBERON_0005133 metanephric glomerulus vasculature http://purl.obolibrary.org/obo/UBERON_0004190 renal glomerulus vasculature The metanephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the metanephric glomerulus[GO]. http://purl.obolibrary.org/obo/GO_0097186 amelogenesis http://purl.obolibrary.org/obo/GO_0042475 odontogenesis of dentin-containing tooth The process whose specific outcome is the formation of tooth enamel, occurring in two stages: secretory stage and maturation stage. http://purl.obolibrary.org/obo/UBERON_0005134 metanephric nephron epithelium http://purl.obolibrary.org/obo/UBERON_0005108 metanephric epithelium The metanephric nephron epithelium is a tissue that covers the surface of a nephron in the metanephros[GO]. http://purl.obolibrary.org/obo/GO_0097306 cellular response to alcohol http://purl.obolibrary.org/obo/GO_0097305 response to alcohol Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alcohol stimulus. http://purl.obolibrary.org/obo/UBERON_0005135 metanephric glomerular epithelium http://purl.obolibrary.org/obo/UBERON_0005134 metanephric nephron epithelium A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros[GO]. http://purl.obolibrary.org/obo/GO_0097530 granulocyte migration http://purl.obolibrary.org/obo/GO_0097529 myeloid leukocyte migration The movement of a granulocyte within or between different tissues and organs of the body. http://purl.obolibrary.org/obo/UBERON_0005136 metanephric glomerular endothelium http://purl.obolibrary.org/obo/UBERON_0005135 metanephric glomerular epithelium The metanephric glomerular endothelium is an epithelial tissue that covers the internal surfaces of the glomerulus of the metanephros[GO]. http://purl.obolibrary.org/obo/GO_0097712 vesicle targeting, trans-Golgi to periciliary membrane compartment http://purl.obolibrary.org/obo/GO_0048199 vesicle targeting, to, from or within Golgi The process in which vesicles formed at the trans-Golgi network are directed to the plasma membrane surrounding the base of the cilium, including the ciliary pocket, mediated by molecules at the vesicle membrane and target membrane surfaces. http://purl.obolibrary.org/obo/UBERON_0005137 metanephric capsule http://purl.obolibrary.org/obo/UBERON_0002015 kidney capsule The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage[GO]. http://purl.obolibrary.org/obo/GO_0097734 extracellular exosome biogenesis http://purl.obolibrary.org/obo/GO_0140112 extracellular vesicle biogenesis The assembly and secretion of an extracellular exosome, a membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. http://purl.obolibrary.org/obo/UBERON_0005140 metanephric short nephron http://purl.obolibrary.org/obo/UBERON_0005110 metanephric nephron Short nephrons are associated with mid-cortical and superficial glomeruli, are situated entirely in the outer medulla, and have no thin ascending limb[GO]. http://purl.obolibrary.org/obo/GO_0098771 inorganic ion homeostasis http://purl.obolibrary.org/obo/GO_0048878 chemical homeostasis Any process involved in the maintenance of an internal steady state of inorganic ions within an organism or cell. http://purl.obolibrary.org/obo/UBERON_0005141 metanephric short descending thin limb http://purl.obolibrary.org/obo/UBERON_0005134 metanephric nephron epithelium The metanephric short descending thin limb is the descending thin limb of a short nephron in the metanephros that has a squamous epithelial morphology[GO]. http://purl.obolibrary.org/obo/GO_0099124 axonal dopamine secretion http://purl.obolibrary.org/obo/GO_0014046 dopamine secretion The regulated release of dopamine from an axon. http://purl.obolibrary.org/obo/UBERON_0005144 metanephric glomerular capillary http://purl.obolibrary.org/obo/UBERON_0004212 glomerular capillary This process pertains to the initial formation of a structure from unspecified parts[GO]. http://purl.obolibrary.org/obo/GO_0099565 chemical synaptic transmission, postsynaptic http://purl.obolibrary.org/obo/GO_0050877 nervous system process The part of synaptic transmission occurring in the post-synapse: a signal transduction pathway consisting of neurotransmitter receptor activation and its effects on postsynaptic membrane potential and the ionic composition of the postsynaptic cytosol. http://purl.obolibrary.org/obo/UBERON_0005145 metanephric comma-shaped body http://purl.obolibrary.org/obo/UBERON_0004198 comma-shaped body The metanephric comma-shaped body is the precursor structure to the metanephric S-shaped body that contributes to the morphogenesis of a nephron in the metanephros[GO]. http://purl.obolibrary.org/obo/GO_0099623 regulation of cardiac muscle cell membrane repolarization http://purl.obolibrary.org/obo/GO_0060306 regulation of membrane repolarization Any process that modulates the establishment or extent of a change in membrane potential in the polarizing direction towards the resting potential in a cardiomyocyte. http://purl.obolibrary.org/obo/UBERON_0005146 metanephric nephron tubule http://purl.obolibrary.org/obo/UBERON_0012275 meso-epithelium A metanephric nephron tubule is an epithelial tube that is part of the metanephric nephron, the functional part of the metanephros[GO]. http://purl.obolibrary.org/obo/GO_0099624 atrial cardiac muscle cell membrane repolarization http://purl.obolibrary.org/obo/GO_0099622 cardiac muscle cell membrane repolarization The process in which ions are transported across the plasma membrane of an atrial cardiac muscle cell such that the membrane potential changes in the repolarizing direction, toward the steady state potential. For example, the repolarization during an action potential is from a positive membrane potential towards a negative resting potential. http://purl.obolibrary.org/obo/UBERON_0005147 metanephric renal vesicle http://purl.obolibrary.org/obo/UBERON_0012275 meso-epithelium The renal vesicle is the primordial structure of the metanephric nephron epithelium, and is formed by the condensation of mesenchymal cells[GO]. http://purl.obolibrary.org/obo/GO_0099625 ventricular cardiac muscle cell membrane repolarization http://purl.obolibrary.org/obo/GO_0099622 cardiac muscle cell membrane repolarization The process in which ions are transported across the plasma membrane of a ventricular cardiac muscle cell such that the membrane potential changes in the repolarizing direction, toward the steady state potential. For example, the repolarization during an action potential is from a positive membrane potential towards a negative resting potential. http://purl.obolibrary.org/obo/UBERON_0005148 metanephric S-shaped body http://purl.obolibrary.org/obo/UBERON_0004199 S-shaped body The metanephric S-shaped body is the successor of the metanephric comma-shaped body that contributes to the morphogenesis of a nephron in the metanephros[GO]. http://purl.obolibrary.org/obo/GO_1900120 regulation of receptor binding http://purl.obolibrary.org/obo/GO_0043393 regulation of protein binding Any process that modulates the frequency, rate or extent of a protein or other molecule binding to a receptor. http://purl.obolibrary.org/obo/UBERON_0005149 metanephric connecting tubule http://purl.obolibrary.org/obo/UBERON_0005146 metanephric nephron tubule The metanephric connecting tubule is a tubular segment of the metanephric nephron; it connects the distal convoluted tubule to the collecting duct in the metanephros[GO]. http://purl.obolibrary.org/obo/GO_1900121 negative regulation of receptor binding http://purl.obolibrary.org/obo/GO_1900120 regulation of receptor binding Any process that stops, prevents or reduces the frequency, rate or extent of a protein or other molecule binding to a receptor. http://purl.obolibrary.org/obo/UBERON_0005151 metanephric proximal tubule http://purl.obolibrary.org/obo/UBERON_0005146 metanephric nephron tubule The metanephric proximal tubule is a metanephric nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle in the metanephros. It has a brush border epithelial morphology[GO]. http://purl.obolibrary.org/obo/GO_1900212 negative regulation of mesenchymal cell apoptotic process involved in metanephros development http://purl.obolibrary.org/obo/GO_2001054 negative regulation of mesenchymal cell apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal cell apoptotic process involved in metanephros development. http://purl.obolibrary.org/obo/UBERON_0005153 epithelial bud http://purl.obolibrary.org/obo/UBERON_0005157 epithelial fold A bud is a protrusion that forms from an epithelial sheet by localized folding. http://purl.obolibrary.org/obo/GO_1901145 mesenchymal cell apoptotic process involved in nephron morphogenesis http://purl.obolibrary.org/obo/GO_0097152 mesenchymal cell apoptotic process Any mesenchymal cell apoptotic process that is involved in nephron morphogenesis. http://purl.obolibrary.org/obo/UBERON_0005154 epithelial cord http://purl.obolibrary.org/obo/UBERON_0000486 multilaminar epithelium A cord of epithelial cells without a lumen and usually several cells thick. http://purl.obolibrary.org/obo/GO_1901343 negative regulation of vasculature development http://purl.obolibrary.org/obo/GO_1901342 regulation of vasculature development Any process that stops, prevents or reduces the frequency, rate or extent of vasculature development. http://purl.obolibrary.org/obo/UBERON_0005155 open tracheal system http://purl.obolibrary.org/obo/UBERON_0001004 respiratory system An open tracheal system is a respiratory system, a branched network of epithelial tubes that supplies oxygen to target tissues via spiracles. An example of this is found in Drosophila melanogaster. http://purl.obolibrary.org/obo/GO_1901653 cellular response to peptide http://purl.obolibrary.org/obo/GO_1901652 response to peptide Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide stimulus. http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure http://purl.obolibrary.org/obo/UBERON_0010000 multicellular anatomical structure Any anatomical structure that is part of the reproductive system. http://purl.obolibrary.org/obo/GO_1901723 negative regulation of cell proliferation involved in kidney development http://purl.obolibrary.org/obo/GO_0008285 negative regulation of cell population proliferation Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation involved in kidney development. http://purl.obolibrary.org/obo/UBERON_0005157 epithelial fold http://purl.obolibrary.org/obo/UBERON_0000483 epithelium An epithelial sheet bent on a linear axis. http://purl.obolibrary.org/obo/GO_1901724 positive regulation of cell proliferation involved in kidney development http://purl.obolibrary.org/obo/GO_0008284 positive regulation of cell population proliferation Any process that activates or increases the frequency, rate or extent of cell proliferation involved in kidney development. http://purl.obolibrary.org/obo/UBERON_0005158 parenchyma of central nervous system http://purl.obolibrary.org/obo/UBERON_0000353 parenchyma The functional tissue of the central nervous system consisting of neurons and glial cells. http://purl.obolibrary.org/obo/UBERON_0005160 vestigial structure http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure A remnant structure from earlier development or evolution. http://purl.obolibrary.org/obo/GO_1902019 regulation of cilium-dependent cell motility http://purl.obolibrary.org/obo/GO_2000145 regulation of cell motility Any process that modulates the frequency, rate or extent of cilium-dependent cell motility. http://purl.obolibrary.org/obo/UBERON_0005162 multi cell part structure http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure A structure consisting mainly of cell components, rather than complete cells. http://purl.obolibrary.org/obo/GO_1902024 L-histidine transport http://purl.obolibrary.org/obo/GO_0015807 L-amino acid transport The directed movement of a L-histidine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/UBERON_0005164 ascending limb of loop of Henle http://purl.obolibrary.org/obo/UBERON_0004135 distal tubule The distal part of the loop of Henle that is impermeable to water and actively pumps sodium out of the filtrate to generate the hypertonic interstitium that drives countercurrent exchange; it consists of an initial very thin segment lined by simple squamous epithelium followed by a distal thick segment lined by simple cuboidal epithelium[MP]. http://purl.obolibrary.org/obo/GO_1902093 positive regulation of flagellated sperm motility http://purl.obolibrary.org/obo/GO_2000243 positive regulation of reproductive process Any process that activates or increases the frequency, rate or extent of flagellated sperm motility. http://purl.obolibrary.org/obo/UBERON_0005167 papillary duct http://purl.obolibrary.org/obo/UBERON_0001232 collecting duct of renal tubule The terminal portions of the medullary collecting ducts are the papillary ducts, which end at the renal papilla and empty into a minor calyx. http://purl.obolibrary.org/obo/GO_1902170 cellular response to reactive nitrogen species http://purl.obolibrary.org/obo/GO_1901699 cellular response to nitrogen compound Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive nitrogen species stimulus. http://purl.obolibrary.org/obo/UBERON_0005168 renal interlobular vein http://purl.obolibrary.org/obo/UBERON_0014401 renal venous blood vessel Any of the veins that parallel the interlobular arteries, receiving blood from the peritubular capillary plexus and empty into the arcuate veins. http://purl.obolibrary.org/obo/GO_1902338 negative regulation of apoptotic process involved in morphogenesis http://purl.obolibrary.org/obo/GO_1904746 negative regulation of apoptotic process involved in development Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in morphogenesis. http://purl.obolibrary.org/obo/UBERON_0005169 interstitial tissue http://purl.obolibrary.org/obo/UBERON_0003891 stroma Connective tissue between the cellular elements of a structure. http://purl.obolibrary.org/obo/GO_1902339 positive regulation of apoptotic process involved in morphogenesis http://purl.obolibrary.org/obo/GO_1904747 positive regulation of apoptotic process involved in development Any process that activates or increases the frequency, rate or extent of apoptotic process involved in morphogenesis. http://purl.obolibrary.org/obo/GO_1902414 protein localization to cell junction http://purl.obolibrary.org/obo/GO_0008104 intracellular protein localization A process in which a protein is transported to, or maintained in, a location within a cell junction. http://purl.obolibrary.org/obo/UBERON_0005170 granulosa cell layer http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure A layer of the ovarian follicle that consists of granulosa cells. http://purl.obolibrary.org/obo/GO_1902866 regulation of retina development in camera-type eye http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of retina development in camera-type eye. http://purl.obolibrary.org/obo/UBERON_0005171 hepatic duct http://purl.obolibrary.org/obo/UBERON_0002394 bile duct Any portion of the ducts that carry bile from the liver to the common bile duct. This may include both intrahapetic components (parts of left and right hepatic ducts) and extrahapetic components (common hepatic duct, plus hilar portion). http://purl.obolibrary.org/obo/GO_1902867 negative regulation of retina development in camera-type eye http://purl.obolibrary.org/obo/GO_1902866 regulation of retina development in camera-type eye Any process that stops, prevents or reduces the frequency, rate or extent of retina development in camera-type eye. http://purl.obolibrary.org/obo/UBERON_0005172 abdomen element http://purl.obolibrary.org/obo/UBERON_0005173 abdominal segment element An organ or element that is in the abdomen. Examples: spleen, intestine, kidney, abdominal mammary gland. http://purl.obolibrary.org/obo/GO_1902868 positive regulation of retina development in camera-type eye http://purl.obolibrary.org/obo/GO_1902866 regulation of retina development in camera-type eye Any process that activates or increases the frequency, rate or extent of retina development in camera-type eye. http://purl.obolibrary.org/obo/UBERON_0005173 abdominal segment element http://purl.obolibrary.org/obo/UBERON_0005177 trunk region element An organ or element that is part of the adbominal segment of the organism. This region can be further subdivided into the abdominal cavity and the pelvic region. http://purl.obolibrary.org/obo/GO_1903296 positive regulation of glutamate secretion, neurotransmission http://purl.obolibrary.org/obo/GO_0051968 positive regulation of synaptic transmission, glutamatergic Any process that activates or increases the frequency, rate or extent of glutamate secretion, where glutamate acts as a neurotransmitter. http://purl.obolibrary.org/obo/UBERON_0005174 dorsal region element http://purl.obolibrary.org/obo/UBERON_0000062 organ An organ or element that part of the dorsum of the organism. Examples: spinal cord, vertebrae, muscles of back. http://purl.obolibrary.org/obo/GO_1903317 regulation of protein maturation http://purl.obolibrary.org/obo/GO_0051246 regulation of protein metabolic process Any process that modulates the frequency, rate or extent of protein maturation. http://purl.obolibrary.org/obo/UBERON_0005175 chest organ http://purl.obolibrary.org/obo/UBERON_0005181 thoracic segment organ An organ that is part of a chest [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_1903489 positive regulation of lactation http://purl.obolibrary.org/obo/GO_1903487 regulation of lactation Any process that activates or increases the frequency, rate or extent of lactation. http://purl.obolibrary.org/obo/UBERON_0005176 tooth enamel organ http://purl.obolibrary.org/obo/UBERON_0034922 cell cluster A circumscribed mass of ectodermal cells which bud off from the dental lamina; it becomes cup-shaped and develops on its internal face the ameloblast layer of cells that produces the enamel cap of a developing tooth. http://purl.obolibrary.org/obo/GO_1903561 extracellular vesicle http://purl.obolibrary.org/obo/GO_0031982 vesicle Any vesicle that is part of the extracellular region. http://purl.obolibrary.org/obo/UBERON_0005177 trunk region element http://purl.obolibrary.org/obo/UBERON_0000062 organ An organ or element that part of the trunk region. The trunk region can be further subdividied into thoracic (including chest and thoracic cavity) and abdominal (including abdomen and pelbis) regions. http://purl.obolibrary.org/obo/GO_1903867 extraembryonic membrane development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of an extraembryonic membrane over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/UBERON_0005178 thoracic cavity element http://purl.obolibrary.org/obo/UBERON_0005181 thoracic segment organ An organ or element that is in the thoracic cavity. Examples: lung, heart, longus colli. http://purl.obolibrary.org/obo/GO_1904019 epithelial cell apoptotic process http://purl.obolibrary.org/obo/GO_0006915 apoptotic process Any apoptotic process in an epithelial cell. http://purl.obolibrary.org/obo/UBERON_0005179 pelvic region element http://purl.obolibrary.org/obo/UBERON_0005173 abdominal segment element An organ or element that is part of the pelvic region. Examples: reproductive organs (in some organisms), urinary bladder, bones of the pelvis. http://purl.obolibrary.org/obo/GO_1904238 pericyte cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a pericyte cell. http://purl.obolibrary.org/obo/UBERON_0005181 thoracic segment organ http://purl.obolibrary.org/obo/UBERON_0005177 trunk region element An organ that part of the thoracic segment region. This region can be further subdividied chest and thoracic cavity regions. http://purl.obolibrary.org/obo/GO_1904672 regulation of somatic stem cell population maintenance http://purl.obolibrary.org/obo/GO_2000036 regulation of stem cell population maintenance Any process that modulates the frequency, rate or extent of somatic stem cell population maintenance. http://purl.obolibrary.org/obo/UBERON_0005184 hair medulla http://purl.obolibrary.org/obo/UBERON_0000958 medulla of organ Innermost layer of the hair shaft. http://purl.obolibrary.org/obo/GO_1904673 negative regulation of somatic stem cell population maintenance http://purl.obolibrary.org/obo/GO_1904672 regulation of somatic stem cell population maintenance Any process that stops, prevents or reduces the frequency, rate or extent of somatic stem cell population maintenance. http://purl.obolibrary.org/obo/UBERON_0005185 renal medulla collecting duct http://purl.obolibrary.org/obo/UBERON_0013522 subdivision of tube The portion of the collecting duct that resides in the renal medulla. http://purl.obolibrary.org/obo/GO_1904674 positive regulation of somatic stem cell population maintenance http://purl.obolibrary.org/obo/GO_1904672 regulation of somatic stem cell population maintenance Any process that activates or increases the frequency, rate or extent of somatic stem cell population maintenance. http://purl.obolibrary.org/obo/UBERON_0005192 deferent duct artery http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure An artery in males that provides blood to the vas deferens. The artery usually arises from the anterior trunk of the superior vesical artery. It accompanies the vas deferens into the testis, where it anastomoses with the testicular artery. In this way it also supplies blood to the testis and epididymis. A small branch supplies the ureter[WP]. http://purl.obolibrary.org/obo/GO_1905153 regulation of membrane invagination http://purl.obolibrary.org/obo/GO_0051128 regulation of cellular component organization Any process that modulates the frequency, rate or extent of membrane invagination. http://purl.obolibrary.org/obo/UBERON_0005194 thoracic vein http://purl.obolibrary.org/obo/UBERON_0003834 thoracic segment blood vessel A vein that is part of a thorax [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_1905154 negative regulation of membrane invagination http://purl.obolibrary.org/obo/GO_1905153 regulation of membrane invagination Any process that stops, prevents or reduces the frequency, rate or extent of membrane invagination. http://purl.obolibrary.org/obo/UBERON_0005195 deferent duct vein http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure A vein that is part of a vas deferens [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_1905155 positive regulation of membrane invagination http://purl.obolibrary.org/obo/GO_1905153 regulation of membrane invagination Any process that activates or increases the frequency, rate or extent of membrane invagination. http://purl.obolibrary.org/obo/UBERON_0005196 spleen germinal center http://purl.obolibrary.org/obo/UBERON_0010754 germinal center A germinal center that is part of the spleen. The spleen germinal center is located in a secondary B follicle in the white pulp of the spleen. http://purl.obolibrary.org/obo/GO_1905276 regulation of epithelial tube formation http://purl.obolibrary.org/obo/GO_2000026 regulation of multicellular organismal development Any process that modulates the frequency, rate or extent of epithelial tube formation. http://purl.obolibrary.org/obo/UBERON_0005199 cervical mammary gland http://purl.obolibrary.org/obo/UBERON_0001911 mammary gland A mammary gland that is part of a cervical region. http://purl.obolibrary.org/obo/GO_1905278 positive regulation of epithelial tube formation http://purl.obolibrary.org/obo/GO_1905276 regulation of epithelial tube formation Any process that activates or increases the frequency, rate or extent of epithelial tube formation. http://purl.obolibrary.org/obo/UBERON_0005200 thoracic mammary gland http://purl.obolibrary.org/obo/UBERON_0005175 chest organ A lactiferous gland that is located in the thoracic region/breast. http://purl.obolibrary.org/obo/GO_1905292 regulation of neural crest cell differentiation http://purl.obolibrary.org/obo/GO_2000736 regulation of stem cell differentiation Any process that modulates the frequency, rate or extent of neural crest cell differentiation. http://purl.obolibrary.org/obo/UBERON_0005202 distal straight tubule macula densa http://purl.obolibrary.org/obo/UBERON_0002335 macula densa A macula densa that is part of an ascending limb of loop of Henle [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_1905293 negative regulation of neural crest cell differentiation http://purl.obolibrary.org/obo/GO_1905292 regulation of neural crest cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of neural crest cell differentiation. http://purl.obolibrary.org/obo/UBERON_0005203 trachea gland http://purl.obolibrary.org/obo/UBERON_8410077 airway submucosal gland A tubuloacinar seromucous gland that is located principally in the submucosa of the trachea. Excretory ducts from this gland pass through the lamina propria to the tracheal lumen. http://purl.obolibrary.org/obo/GO_1905294 positive regulation of neural crest cell differentiation http://purl.obolibrary.org/obo/GO_1905292 regulation of neural crest cell differentiation Any process that activates or increases the frequency, rate or extent of neural crest cell differentiation. http://purl.obolibrary.org/obo/UBERON_0005204 larynx submucosa gland http://purl.obolibrary.org/obo/UBERON_0036225 respiratory system gland A gland that is part of a larynx submucosa [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_1905349 ciliary transition zone assembly http://purl.obolibrary.org/obo/GO_0022607 cellular component assembly The aggregation, arrangement and bonding together of a set of components to form a ciliary transition zone. http://purl.obolibrary.org/obo/UBERON_0005206 choroid plexus stroma http://purl.obolibrary.org/obo/UBERON_0003891 stroma Stromal matrix surrounding blood vessels within the choroid plexus. http://purl.obolibrary.org/obo/UBERON_0005207 tonsil capsule http://purl.obolibrary.org/obo/UBERON_0003893 capsule A capsule that is part of a tonsil [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_1905508 protein localization to microtubule organizing center http://purl.obolibrary.org/obo/GO_0072698 protein localization to microtubule cytoskeleton A process in which a protein is transported to, or maintained in, a location within a microtubule organizing center. http://purl.obolibrary.org/obo/UBERON_0005208 right atrium valve http://purl.obolibrary.org/obo/UBERON_0003978 valve A valve that is part of a right atrium [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_1905516 positive regulation of fertilization http://purl.obolibrary.org/obo/GO_2000243 positive regulation of reproductive process Any process that activates or increases the frequency, rate or extent of fertilization. http://purl.obolibrary.org/obo/UBERON_0005211 renal medulla interstitium http://purl.obolibrary.org/obo/UBERON_0005215 kidney interstitium Tissue surrounding the loop of Henle in the renal medulla. http://purl.obolibrary.org/obo/GO_1905634 regulation of protein localization to chromatin http://purl.obolibrary.org/obo/GO_0032880 regulation of protein localization Any process that modulates the frequency, rate or extent of protein localization to chromatin. http://purl.obolibrary.org/obo/UBERON_0005212 Leydig cell region of testis http://purl.obolibrary.org/obo/UBERON_0005169 interstitial tissue The male gonad containing two functional parts: the SEMINIFEROUS TUBULES for the production and transport of male germ cells (SPERMATOGENESIS) and the interstitial compartment containing LEYDIG CELLS that produce ANDROGENS.. http://purl.obolibrary.org/obo/GO_1905809 negative regulation of synapse organization http://purl.obolibrary.org/obo/GO_0051129 negative regulation of cellular component organization Any process that stops, prevents or reduces the frequency, rate or extent of synapse organization. http://purl.obolibrary.org/obo/UBERON_0005213 outer renal medulla interstitium http://purl.obolibrary.org/obo/UBERON_0005211 renal medulla interstitium A portion of interstitial tissue that is part of a outer medulla of kidney [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_1990504 dense core granule exocytosis http://purl.obolibrary.org/obo/GO_0017156 calcium-ion regulated exocytosis The secretion of molecules (e.g. neuropeptides, insulin-related peptides or neuromodulators such as serotonin and dopamine) contained within a membrane-bounced dense core granule by fusion of the granule with the plasma membrane of a cell in response to increased cytosolic calcium levels. http://purl.obolibrary.org/obo/UBERON_0005214 inner renal medulla interstitium http://purl.obolibrary.org/obo/UBERON_0005211 renal medulla interstitium A portion of interstitial tissue that is part of a inner medulla of kidney [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_1990748 cellular detoxification http://purl.obolibrary.org/obo/GO_0098754 detoxification Any process carried out at the cellular level that reduces or removes the toxicity of a toxic substance. These may include transport of the toxic substance away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance. http://purl.obolibrary.org/obo/UBERON_0005215 kidney interstitium http://purl.obolibrary.org/obo/UBERON_0005169 interstitial tissue The interstitial compartment of the kidney, comprising the extravascular intertubular spaces of the renal parenchyma, with their attendant cellular elements and extracellular substances, bounded on all sides by epithelial and vascular basement membranes. http://purl.obolibrary.org/obo/GO_2000070 regulation of response to water deprivation http://purl.obolibrary.org/obo/GO_0080134 regulation of response to stress Any process that modulates the frequency, rate or extent of response to water deprivation. http://purl.obolibrary.org/obo/UBERON_0005217 midbrain subarachnoid space http://purl.obolibrary.org/obo/UBERON_0039175 subarachnoid space of brain A subarachnoid space that is part of a midbrain [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_2000183 negative regulation of progesterone biosynthetic process http://purl.obolibrary.org/obo/GO_0010894 negative regulation of steroid biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of progesterone biosynthetic process. http://purl.obolibrary.org/obo/UBERON_0005218 diencephalon subarachnoid space http://purl.obolibrary.org/obo/UBERON_0039175 subarachnoid space of brain A subarachnoid space that is part of a diencephalon [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_2000543 positive regulation of gastrulation http://purl.obolibrary.org/obo/GO_0010470 regulation of gastrulation Any process that activates or increases the frequency, rate or extent of gastrulation. http://purl.obolibrary.org/obo/UBERON_0005219 hindbrain subarachnoid space http://purl.obolibrary.org/obo/UBERON_0039175 subarachnoid space of brain A subarachnoid space that is part of a hindbrain [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_2000725 regulation of cardiac muscle cell differentiation http://purl.obolibrary.org/obo/GO_0051153 regulation of striated muscle cell differentiation Any process that modulates the frequency, rate or extent of cardiac muscle cell differentiation. http://purl.obolibrary.org/obo/UBERON_0005221 liver right lobe parenchyma http://purl.obolibrary.org/obo/UBERON_0001280 liver parenchyma A parenchyma that is part of a right lobe of liver [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_2000726 negative regulation of cardiac muscle cell differentiation http://purl.obolibrary.org/obo/GO_2000725 regulation of cardiac muscle cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle cell differentiation. http://purl.obolibrary.org/obo/UBERON_0005222 liver left lobe parenchyma http://purl.obolibrary.org/obo/UBERON_0001280 liver parenchyma A parenchyma that is part of a left lobe of liver [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_2000727 positive regulation of cardiac muscle cell differentiation http://purl.obolibrary.org/obo/GO_2000725 regulation of cardiac muscle cell differentiation Any process that activates or increases the frequency, rate or extent of cardiac muscle cell differentiation. http://purl.obolibrary.org/obo/UBERON_0005225 upper leg epithelium http://purl.obolibrary.org/obo/UBERON_0000483 epithelium An epithelium that is part of a hindlimb stylopod [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_2000794 regulation of epithelial cell proliferation involved in lung morphogenesis http://purl.obolibrary.org/obo/GO_0050678 regulation of epithelial cell proliferation Any process that modulates the frequency, rate or extent of epithelial cell proliferation involved in lung morphogenesis. http://purl.obolibrary.org/obo/UBERON_0005226 pedal digit epithelium http://purl.obolibrary.org/obo/UBERON_0000490 unilaminar epithelium An epithelium that is part of a toe [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_2001013 epithelial cell proliferation involved in renal tubule morphogenesis http://purl.obolibrary.org/obo/GO_0050673 epithelial cell proliferation Any epithelial cell proliferation that is involved in renal tubule morphogenesis. http://purl.obolibrary.org/obo/UBERON_0005227 manual digit epithelium http://purl.obolibrary.org/obo/UBERON_0000490 unilaminar epithelium An epithelium that is part of a finger [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_2001053 regulation of mesenchymal cell apoptotic process http://purl.obolibrary.org/obo/GO_0042981 regulation of apoptotic process Any process that modulates the frequency, rate or extent of mesenchymal cell apoptotic process. http://purl.obolibrary.org/obo/UBERON_0005228 upper arm epithelium http://purl.obolibrary.org/obo/UBERON_0000483 epithelium An epithelium that is part of a forelimb stylopod [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_2001054 negative regulation of mesenchymal cell apoptotic process http://purl.obolibrary.org/obo/GO_2001053 regulation of mesenchymal cell apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal cell apoptotic process. http://purl.obolibrary.org/obo/UBERON_0005229 lower leg epithelium http://purl.obolibrary.org/obo/UBERON_0000483 epithelium An epithelium that is part of a lower leg [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_2001055 positive regulation of mesenchymal cell apoptotic process http://purl.obolibrary.org/obo/GO_2001053 regulation of mesenchymal cell apoptotic process Any process that activates or increases the frequency, rate or extent of mesenchymal cell apoptotic process. http://purl.obolibrary.org/obo/UBERON_0005233 medial-nasal process ectoderm http://purl.obolibrary.org/obo/UBERON_0014702 frontonasal process epithelium An ectoderm that is part of a medial nasal prominence [Automatically generated definition]. http://purl.obolibrary.org/obo/PR_000008982 interleukin-17 receptor B http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human IL17RB gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0005234 optic eminence ectoderm http://purl.obolibrary.org/obo/UBERON_0000924 ectoderm An ectoderm that is part of a optic eminence [Automatically generated definition]. http://purl.obolibrary.org/obo/PR_000008994 interleukin-1 receptor-like 1 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human IL1RL1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0005243 interventricular septum endocardium http://purl.obolibrary.org/obo/UBERON_0002165 endocardium An endocardium that is part of a interventricular septum [Automatically generated definition]. http://purl.obolibrary.org/obo/PR_000009054 preproinsulin http://purl.obolibrary.org/obo/PR_000045358 insulin family protein An insulin family protein that is a translation product of the human INS gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0005248 bulbus cordis myocardium http://purl.obolibrary.org/obo/UBERON_0002349 myocardium A myocardium that is part of a bulbus cordis [Automatically generated definition]. http://purl.obolibrary.org/obo/PR_000009127 integrin alpha-IIb http://purl.obolibrary.org/obo/PR_000025797 integrin alpha lacking A domain An integrin alpha lacking A domain that is a translation product of the human ITGA2B gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0005249 metanephric renal pelvis http://purl.obolibrary.org/obo/UBERON_0001224 renal pelvis A renal pelvis that is part of a metanephros. http://purl.obolibrary.org/obo/PR_000009129 integrin alpha-4 http://purl.obolibrary.org/obo/PR_000025797 integrin alpha lacking A domain An integrin alpha lacking A domain that is a translation product of the human ITGA4 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0005250 stomatodeum gland http://purl.obolibrary.org/obo/UBERON_0002530 gland A gland that is part of a stomodeum. http://purl.obolibrary.org/obo/PR_000009143 integrin beta-7 http://purl.obolibrary.org/obo/PR_000001861 integrin beta An integrin beta that is a translation product of the human ITGB7 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0005251 yolk sac cavity http://purl.obolibrary.org/obo/UBERON_0012466 extraembryonic cavity An anatomical cavity that is part of a yolk sac [Automatically generated definition]. http://purl.obolibrary.org/obo/PR_000009344 metastasis-suppressor KiSS-1 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human KISS1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0005253 head mesenchyme http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue Portion of primordial embryonic connective tissue of the developing head, consisting of mesenchymal cells supported in interlaminar jelly, that derive mostly from the mesoderm and contribute to head connective tissue, bone and musculature in conjunction with cranial neural crest cells. http://purl.obolibrary.org/obo/PR_000009426 killer cell lectin-like receptor subfamily G member 1 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human KLRG1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0005254 upper leg mesenchyme http://purl.obolibrary.org/obo/UBERON_0003860 hindlimb mesenchyme Mesenchyme that is part of a developing hindlimb stylopod [Automatically generated definition]. http://purl.obolibrary.org/obo/PR_000009616 T-cell surface glycoprotein YE1/48 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the mouse Klra1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0005255 pedal digit mesenchyme http://purl.obolibrary.org/obo/UBERON_0010702 digit mesenchyme Mesenchyme that is part of a developing toe [Automatically generated definition]. http://purl.obolibrary.org/obo/PR_000009618 killer cell lectin-like receptor 3 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the mouse Klra3 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0005256 trunk mesenchyme http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue Mesenchyme that is part of a developing trunk. http://purl.obolibrary.org/obo/PR_000009619 killer cell lectin-like receptor 4 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the mouse Klra4 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0005257 manual digit mesenchyme http://purl.obolibrary.org/obo/UBERON_0010702 digit mesenchyme Mesenchyme that is part of a developing finger [Automatically generated definition]. http://purl.obolibrary.org/obo/PR_000009623 killer cell lectin-like receptor 8 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the mouse Klra8 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0005258 upper arm mesenchyme http://purl.obolibrary.org/obo/UBERON_0003859 forelimb mesenchyme Mesenchyme that is part of a developing forelimb stylopod [Automatically generated definition]. http://purl.obolibrary.org/obo/PR_000009725 neutrophil gelatinase-associated lipocalin http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human LCN2 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0005259 lower leg mesenchyme http://purl.obolibrary.org/obo/UBERON_0003860 hindlimb mesenchyme Mesenchyme that is part of a developing lower leg [Automatically generated definition]. http://purl.obolibrary.org/obo/PR_000009766 galectin-1 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human LGALS1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0005268 renal cortex artery http://purl.obolibrary.org/obo/UBERON_0003644 kidney arterial blood vessel An artery that supplies the renal cortex. http://purl.obolibrary.org/obo/PR_000009793 LIM/homeobox protein Lhx3 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human LHX3 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0005269 renal cortex vein http://purl.obolibrary.org/obo/UBERON_0014401 renal venous blood vessel Artery that receives blood from the renal cortex[MP, modified]. http://purl.obolibrary.org/obo/PR_000009978 lactotransferrin http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human LTF gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0005270 renal cortex interstitium http://purl.obolibrary.org/obo/UBERON_0005215 kidney interstitium A compartment of the renal cortex situated between basement membranes of epithelia and vessels that contains two contiguous cellular networks in mutual contact, one formed by interstitial fibroblasts, the other by dendritic cells. http://purl.obolibrary.org/obo/PR_000009981 lumican http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human LUM gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0005271 juxtamedullary cortex http://purl.obolibrary.org/obo/UBERON_0000064 organ part The part of the renal cortex nearest to the medulla. http://purl.obolibrary.org/obo/PR_000010317 homeobox protein Meis2 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human MEIS2 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0005272 peritubular capillary http://purl.obolibrary.org/obo/UBERON_0003527 kidney capillary The tiny blood vessels that receive blood from the efferent arterioles of the glomerulus, and interact with superficial cortical nephrons allowing reabsorption and secretion between blood and the inner lumen of the nephron; peritubular capillaries are situated around the tubule and are at low pressure. http://purl.obolibrary.org/obo/PR_000010329 tyrosine-protein kinase Mer http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human MERTK gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0005273 nail bed http://purl.obolibrary.org/obo/UBERON_0005275 dorsal skin of digit Region of skin beneath the nail plate[WP]. http://purl.obolibrary.org/obo/PR_000010529 DBH-like monooxygenase protein 1 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human MOXD1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0005276 dorsal skin of finger http://purl.obolibrary.org/obo/UBERON_0005275 dorsal skin of digit A dorsal skin of digit that is part of a manual digit. http://purl.obolibrary.org/obo/PR_000010799 myb proto-oncogene protein http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human MYB gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0005277 dorsal skin of toe http://purl.obolibrary.org/obo/UBERON_0005275 dorsal skin of digit A dorsal skin of digit that is part of a pedal digit. http://purl.obolibrary.org/obo/PR_000011118 neurofilament heavy polypeptide http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human NEFH gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0005278 nail bed of finger http://purl.obolibrary.org/obo/UBERON_0005276 dorsal skin of finger A nail bed that is part of a manual digit. http://purl.obolibrary.org/obo/PR_000011143 neuropilin and tolloid-like protein 1 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human NETO1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0005279 nail bed of toe http://purl.obolibrary.org/obo/UBERON_0005277 dorsal skin of toe A nail bed that is part of a pedal digit. http://purl.obolibrary.org/obo/PR_000011178 nuclear factor NF-kappa-B p100 subunit http://purl.obolibrary.org/obo/PR_000001753 transcription factor NF-kappa-B subunit A transcription factor NF-kappa-B subunit that is a translation product of the human NFKB2 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0005281 ventricular system of central nervous system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system A set of structures containing cerebrospinal fluid in the brain. It is continuous with the central canal of the spinal cord[WP]. http://purl.obolibrary.org/obo/PR_000011241 homeobox protein Nkx-2.1 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human NKX2-1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0005283 tela choroidea http://purl.obolibrary.org/obo/UBERON_0004923 organ component layer A structure found in the walls of the ventricles of the brain, consisting of part of the meninges (pia mater in mammals) plus ependyma[cjm]. http://purl.obolibrary.org/obo/PR_000011326 nitric oxide synthase 1 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human NOS1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0005287 tela choroidea of fourth ventricle http://purl.obolibrary.org/obo/UBERON_0005283 tela choroidea Tela chorioidea that lines the fourth ventricle[ZFA]. The tela chorioidea of the fourth ventricle is the name applied to the triangular fold of pia mater which is carried upward between the cerebellum and the medulla oblongata. It consists of two layers, which are continuous with each other in front, and are more or less adherent throughout: The posterior layer covers the antero-inferior surface of the cerebellum. The anterior layer is applied to the structures which form the lower part of the roof of the ventricle, and is continuous inferiorly with the pia mater on the inferior peduncles and closed part of the medulla[WP]. http://purl.obolibrary.org/obo/PR_000011387 neuropeptide Y http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human NPY gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0005288 tela choroidea of third ventricle http://purl.obolibrary.org/obo/UBERON_0005283 tela choroidea Tela chorioidea that lines the third ventricle[ZFA]. The part of the choroid plexus in relation to the body of the ventricle forms the vascular fringed margin of a triangular process of pia mater, named the tela chorioidea of the third ventricle, and projects from under cover of the lateral edge of the fornix. Blood is supplied by branches from the superior cerebellar artery[WP]. http://purl.obolibrary.org/obo/PR_000011467 netrin-G1 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human NTNG1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0005289 tela choroidea of telencephalic ventricle http://purl.obolibrary.org/obo/UBERON_0005283 tela choroidea Tela chorioidea that lines the telencephalic ventricle. http://purl.obolibrary.org/obo/PR_000012190 P2X purinoceptor 3 http://purl.obolibrary.org/obo/PR_000044669 P2X receptor protein A P2X receptor protein that is a translation product of the human P2RX3 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0005290 myelencephalon http://purl.obolibrary.org/obo/UBERON_0004733 segmental subdivision of hindbrain The posterior part of the developing vertebrate hindbrain or the corresponding part of the adult brain composed of the medulla oblongata and a portion of the fourth ventricle; as well as the glossopharyngeal nerve (CN IX), vagus nerve (CN X), accessory nerve (CN XI), hypoglossal nerve (CN XII), and a portion of the vestibulocochlear nerve (CN VIII).[BTO,WP]. http://purl.obolibrary.org/obo/PR_000012318 paired box protein Pax-6 http://purl.obolibrary.org/obo/PR_000037798 paired box protein PAX group IV A paired box protein PAX group IV that is a translation product of the human PAX6 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue http://purl.obolibrary.org/obo/UBERON_0000479 tissue A portion of tissue that is part of an embryo. http://purl.obolibrary.org/obo/PR_000012526 proenkephalin-B http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human PDYN gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0005292 extraembryonic tissue http://purl.obolibrary.org/obo/UBERON_0000479 tissue Portion of tissue that is contiguous with the embryo and is comprised of portions of tissue or cells that will not contribute to the embryo. http://purl.obolibrary.org/obo/PR_000012544 proenkephalin-A http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human PENK gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0005293 cerebellum lobe http://purl.obolibrary.org/obo/UBERON_0002749 regional part of cerebellar cortex A major subdivision of the cerebellum: anterior, posterior and flocculonodular. http://purl.obolibrary.org/obo/PR_000013015 pro-opiomelanocortin http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human POMC gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0005294 gonadal ridge http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure The elevation of thickened mesothelium and underlying mesenchyme found on the ventromedial border of the embryonic mesonephros in which the primordial germ cells become embedded, establishing it as the primordium of the testis or ovary. http://purl.obolibrary.org/obo/PR_000013031 periostin http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human POSTN gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0005295 sex cord http://purl.obolibrary.org/obo/UBERON_0012275 meso-epithelium Cordlike masses of epithelial tissue that invaginate from germinal epithelium of the gonad and give rise to seminiferous tubules and rete testes in the male, and primary ovarian follicles and rete ovarii in the female. http://purl.obolibrary.org/obo/PR_000013041 POU domain, class 4, transcription factor 1 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human POU4F1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0005296 ovary sex cord http://purl.obolibrary.org/obo/UBERON_0005295 sex cord Structures that develop from sex cords in the female. After further development they become the ovarian follicles. http://purl.obolibrary.org/obo/PR_000013047 POU domain, class 6, transcription factor 2 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human POU6F2 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0005297 testis sex cord http://purl.obolibrary.org/obo/UBERON_0005295 sex cord The testis cords are precursors to the rete testis. They play several different roles in the development of the male genitals[WP]. http://purl.obolibrary.org/obo/PR_000013206 bone marrow proteoglycan http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human PRG2 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0005298 skin of clitoris http://purl.obolibrary.org/obo/UBERON_8480029 skin of external genitalia A zone of skin that is part of a clitoris [Automatically generated definition]. http://purl.obolibrary.org/obo/PR_000013208 proteoglycan 4 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human PRG4 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0005299 prepuce of clitoris http://purl.obolibrary.org/obo/UBERON_0011374 prepuce A retractable double-layered fold of skin and mucous membrane that covers the clitoral glans. http://purl.obolibrary.org/obo/PR_000013246 prolactin http://purl.obolibrary.org/obo/PR_000029968 somatotropin hormone family member A somatotropin hormone family member that is a translation product of the human PRL gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0005305 thyroid follicle http://purl.obolibrary.org/obo/UBERON_0000064 organ part Discrete, cystlike units of the thyroid gland that are lined with cuboidal epithelium and are filled with a colloid substance, about 30 to each lobule[BTO]. http://purl.obolibrary.org/obo/PR_000013289 peripherin http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human PRPH gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0005309 pronephric nephron http://purl.obolibrary.org/obo/UBERON_0001285 nephron A pronephric nephron is the functional unit of the pronephros[GO]. http://purl.obolibrary.org/obo/PR_000013433 parathyroid hormone-related protein http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human PTHLH gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0005310 pronephric nephron tubule http://purl.obolibrary.org/obo/UBERON_0001231 nephron tubule The pronephric nephron tubule is an epithelial tube that is part of the pronephric nephron and connects the filtration unit (glomerulus or glomus) of the pronephros to the pronephric duct[GO]. http://purl.obolibrary.org/obo/PR_000013502 parvalbumin alpha http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human PVALB gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0005311 mammary placode http://purl.obolibrary.org/obo/UBERON_0011814 non-neurogenic ectodermal placode The mammary placode is a transient lens shaped structure that will give rise to the mammary bud proper[GO]. http://purl.obolibrary.org/obo/PR_000013879 reelin http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human RELN gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0005316 endocardial endothelium http://purl.obolibrary.org/obo/UBERON_0008307 heart endothelium The endothelial lining of the endocardium. http://purl.obolibrary.org/obo/PR_000013883 renin http://purl.obolibrary.org/obo/PR_000050025 angiotensinogenase An angiotensinogenase that is a translation product of the human REN gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0005317 pulmonary artery endothelium http://purl.obolibrary.org/obo/UBERON_0001917 endothelium of artery An pulmonary artery endothelium is an epithelium that lines the pulmonary artery[GO]. http://purl.obolibrary.org/obo/PR_000013895 proto-oncogene tyrosine-protein kinase receptor Ret http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human RET gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0005319 mesonephric collecting duct http://purl.obolibrary.org/obo/UBERON_0001232 collecting duct of renal tubule The collecting duct is the final common path through which urine flows before entering the ureter and then emptying into the bladder[GO]. http://purl.obolibrary.org/obo/PR_000014046 non-secretory ribonuclease http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human RNASE2 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0005320 mesonephric juxtaglomerular apparatus http://purl.obolibrary.org/obo/UBERON_0002303 juxtaglomerular apparatus The juxtaglomerular apparatus lies adjacent to the glomerulus and regulates kidney function by maintaining the blood flow to the kidney and the filtration rate[GO]. http://purl.obolibrary.org/obo/PR_000014047 eosinophil cationic protein http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human RNASE3 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0005321 mesonephric smooth muscle tissue http://purl.obolibrary.org/obo/UBERON_0001135 smooth muscle tissue Missing definition for term UBERON:0005321. Please replace it using linked reference. http://purl.obolibrary.org/obo/PR_000014362 runt-related transcription factor 1 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human RUNX1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0005322 mesonephric nephron http://purl.obolibrary.org/obo/UBERON_0001285 nephron A nephron that is part of a mesonephros. http://purl.obolibrary.org/obo/UBERON_0005323 mesonephric mesenchyme http://purl.obolibrary.org/obo/UBERON_0003104 mesenchyme Mesonephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the mesonephros[GO]. http://purl.obolibrary.org/obo/PR_000014419 protein S100-B http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human S100B gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0005324 mesonephric macula densa http://purl.obolibrary.org/obo/UBERON_0005330 mesonephric nephron epithelium The mesonephric macula densa is an area of specialized cells in the distal tubule of the mesonephros that makes contact with the vascular pole of the glomerulus[GO]. http://purl.obolibrary.org/obo/PR_000014505 uteroglobin http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human SCGB1A1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0005325 mesonephric glomerulus http://purl.obolibrary.org/obo/UBERON_0000074 renal glomerulus The mesonephric glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the mature vertebrate kidney, or mesonephros[GO]. http://purl.obolibrary.org/obo/PR_000025797 integrin alpha lacking A domain http://purl.obolibrary.org/obo/PR_000025796 integrin alpha An integrin alpha that lacks an A domain. This type of integrin is often cleaved into heavy and light chains. http://purl.obolibrary.org/obo/UBERON_0005326 mesonephric glomerulus vasculature http://purl.obolibrary.org/obo/UBERON_0004190 renal glomerulus vasculature The mesonephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the mesonephric glomerulus[GO]. http://purl.obolibrary.org/obo/PR_000027795 trypsin http://purl.obolibrary.org/obo/PR_000000001 protein A protein that in active form is a serine protease that cleaves peptide bonds on the carboxyl side of lysine or arginine amino acids within amino acid chains. http://purl.obolibrary.org/obo/UBERON_0005327 mesonephric glomerular epithelium http://purl.obolibrary.org/obo/UBERON_0005330 mesonephric nephron epithelium A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the mesonephros[GO]. http://purl.obolibrary.org/obo/PR_000037798 paired box protein PAX group IV http://purl.obolibrary.org/obo/PR_000037797 paired box protein PAX A paired box protein PAX that contains, in addition to the 'Paired box' domain (Pfam:PF00292), a C-terminal Homeobox domain (Pfam:PF00046). http://purl.obolibrary.org/obo/UBERON_0005328 mesonephric comma-shaped body http://purl.obolibrary.org/obo/UBERON_0004198 comma-shaped body The mesonephric comma-shaped body is the precursor structure to the mesonephric S-shaped body that contributes to the morphogenesis of a nephron in the mesonephros[GO]. http://purl.obolibrary.org/obo/PR_000045358 insulin family protein http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of a gene that encodes a standalone Insulin (Pfam:PF00049) domain preceded by a signal peptide. http://purl.obolibrary.org/obo/UBERON_0005329 mesonephric nephron tubule http://purl.obolibrary.org/obo/UBERON_0005330 mesonephric nephron epithelium A mesonephric nephron tubule is an epithelial tube that is part of the mesonephric nephron, the functional part of the mesonephros[GO]. http://purl.obolibrary.org/obo/PR_000037797 paired box protein PAX http://purl.obolibrary.org/obo/PR_000000001 protein A protein that contains a copy of the 'Paired box' domain (Pfam:PF00292), a conserved amino acid motif with DNA-binding activity. Members of this class are transcription factors involved in pattern formation during embryogenesis, possibly by determining the time and place of organ initiation or morphogenesis. http://purl.obolibrary.org/obo/UBERON_0005330 mesonephric nephron epithelium http://purl.obolibrary.org/obo/UBERON_0005103 mesonephric epithelium The mesonephric nephron epithelium is a tissue that covers the surface of a nephron in the mesonephros[GO]. http://purl.obolibrary.org/obo/PR_Q62226 sonic hedgehog protein (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A sonic hedgehog protein that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0005331 mesonephric renal vesicle http://purl.obolibrary.org/obo/UBERON_0005103 mesonephric epithelium The renal vesicle is the primordial structure of the mesonephric nephron epithelium, and is formed by the condensation of mesenchymal cells[GO]. http://purl.obolibrary.org/obo/PR_Q9P2W7 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0005332 mesonephric S-shaped body http://purl.obolibrary.org/obo/UBERON_0004199 S-shaped body The mesonephric S-shaped body is the successor of the mesonephric comma-shaped body that contributes to the morphogenesis of a nephron in the mesonephros[GO]. http://purl.obolibrary.org/obo/PR_O35205 granzyme K (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A granzyme K that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0005333 mammary bud http://purl.obolibrary.org/obo/UBERON_0010371 ecto-epithelium A bulb of epithelial cells that forms from the mammary placode that develops into the mammary gland. http://purl.obolibrary.org/obo/PR_O35304 vesicular acetylcholine transporter (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A vesicular acetylcholine transporter that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0005334 oral lamina propria http://purl.obolibrary.org/obo/UBERON_0000030 lamina propria A lamina propria that is part of a mucosa of oral region. http://purl.obolibrary.org/obo/PR_O35305 tumor necrosis factor receptor superfamily member 11A (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A tumor necrosis factor receptor superfamily member 11A that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0005337 outflow tract of ventricle http://purl.obolibrary.org/obo/UBERON_0004145 outflow tract A ventricular outflow tract is a portion of either the left ventricle or right ventricle of the heart through which blood passes in order to enter the great arteries. The right ventricular outflow tract (RVOT) is an infundibular extension of the ventricular cavity which connects to the pulmonary artery. The left ventricular outflow tract (LVOT), which connects to the aorta, is nearly indistinguishable from the rest of the ventricle[WP]. http://purl.obolibrary.org/obo/PR_O35417 proenkephalin-B (mouse) http://purl.obolibrary.org/obo/PR_000012526 proenkephalin-B A proenkephalin-B that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0005338 outflow tract aortic component http://purl.obolibrary.org/obo/UBERON_0004145 outflow tract An outflow tract that is part of a aorta. http://purl.obolibrary.org/obo/PR_O35930 platelet glycoprotein Ib alpha chain (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A platelet glycoprotein Ib alpha chain that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0005340 dorsal telencephalic commissure http://purl.obolibrary.org/obo/UBERON_0019294 commissure of telencephalon A fiber tracts that connect the dorsal region of the two cerebral hemispheres and span the longitudinal fissure, including the corpus callosum and hippocampal commissure[MP]. http://purl.obolibrary.org/obo/PR_O43490 prominin-1 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A prominin-1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0005343 cortical plate http://purl.obolibrary.org/obo/UBERON_0014950 layer of developing cerebral cortex The outer neural tube region in which post-mitotic neuroblasts migrate along radial glia to form the adult cortical layers[MP]. http://purl.obolibrary.org/obo/PR_O54689 C-C chemokine receptor type 6 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A C-C chemokine receptor type 6 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0005356 Rathke's pouch http://purl.obolibrary.org/obo/UBERON_0010371 ecto-epithelium A pouch of ectoderm that grows out from the upper surface of the embryonic stomodeum and gives rise to the anterior and intermediate lobes of the pituitary gland[MP]. In embryogenesis, Rathke's pouch is a depression in the roof of the developing mouth in front of the buccopharyngeal membrane. It gives rise to the anterior pituitary (adenohypophysis), a part of the endocrine system[WP]. http://purl.obolibrary.org/obo/PR_O54707 natural killer cells antigen CD94 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A killer cell lectin-like receptor subfamily D member 1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0005357 brain ependyma http://purl.obolibrary.org/obo/UBERON_0004670 ependyma The ependymal cell layer that lines the brain ventricles. http://purl.obolibrary.org/obo/PR_O54839 eomesodermin homolog (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein An eomesodermin that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0005358 ventricle of nervous system http://purl.obolibrary.org/obo/UBERON_0004923 organ component layer A layer in the central nervous system that lines system of communicating cavities in the brain and spinal cord. http://purl.obolibrary.org/obo/PR_O54990 prominin-1 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A prominin-1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0005359 spinal cord ependyma http://purl.obolibrary.org/obo/UBERON_0004670 ependyma The ependymal cell layer that lines the spinal cord. http://purl.obolibrary.org/obo/PR_P0CW03 lymphocyte antigen 6C2 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A lymphocyte antigen 6C2 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0005362 vagus X ganglion http://purl.obolibrary.org/obo/UBERON_0009127 epibranchial ganglion The group of sensory neuron cell bodies associated with the vagus nerve. http://purl.obolibrary.org/obo/PR_P0DN78 medium-wave-sensitive opsin 3 (human) http://purl.obolibrary.org/obo/PR_000050522 medium-wave-sensitive opsin (human) A medium-wave-sensitive opsin (human) that is a translation product of the OPN1MW3 gene in human. http://purl.obolibrary.org/obo/UBERON_0005363 inferior vagus X ganglion http://purl.obolibrary.org/obo/UBERON_0010313 neural crest-derived structure The large group of sensory neuron cell bodies, anterior to the jugular vein, associated with the vagus nerve (tenth cranial nerve). http://purl.obolibrary.org/obo/PR_P10144 granzyme B (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A granzyme B that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0005364 superior vagus X ganglion http://purl.obolibrary.org/obo/UBERON_0005362 vagus X ganglion The upper ganglion of the vagus nerve located at the jugular foramen. http://purl.obolibrary.org/obo/PR_P10153 non-secretory ribonuclease (human) http://purl.obolibrary.org/obo/PR_000014046 non-secretory ribonuclease A non-secretory ribonuclease that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0005366 olfactory lobe http://purl.obolibrary.org/obo/UBERON_0016526 lobe of cerebral hemisphere The lobe at the anterior part of each cerebral hemisphere, responsible for olfactory functions. http://purl.obolibrary.org/obo/PR_P10300 T-cell surface glycoprotein CD8 beta chain (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A T-cell surface glycoprotein CD8 beta chain that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0005371 hippocampus stratum oriens http://purl.obolibrary.org/obo/UBERON_0002305 layer of hippocampus Layer that is part of the CA fields of the hippocampus consisting of a narrow relatively cell free layer located deep to the pyramidal cell layer extending through areas CA1, CA2 and CA3. (adapted from Paxinos The rat central nervous system, 2nd ed, Academic Press, San Diego, 1995). http://purl.obolibrary.org/obo/PR_P10810 monocyte differentiation antigen CD14 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A CD14 molecule that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0005372 hippocampus stratum radiatum http://purl.obolibrary.org/obo/UBERON_0002305 layer of hippocampus The layer located immediately above the pyramidal cell layer in CA2 and CA1 and superficial to the stratum lucidum in CA3. Suprapyramidal region in which CA3 to CA3 associational connections and CA3 to CA1 Schaffer collateral connections are located. http://purl.obolibrary.org/obo/PR_P10820 perforin-1 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A perforin-1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0005375 spinal cord ventral column http://purl.obolibrary.org/obo/UBERON_0016550 spinal cord column The area of white matter of the spinal cord located on either side of the ventral (anterior) medial fissure. http://purl.obolibrary.org/obo/PR_P10855 C-C motif chemokine 3 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A C-C motif chemokine 3 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0005376 olfactory bulb external plexiform layer http://purl.obolibrary.org/obo/UBERON_0009950 olfactory bulb plexiform layer Cytoarchitectural part of the olfactory bulb, lying superior to the mitral cell layer and inferior to the glomerular layer. The EPL is mostly neuropil composed almost entirely of mitral and tulfted cell dendrites and granule cell dendrites and their synaptic inputs. http://purl.obolibrary.org/obo/PR_P10966-1 T-cell surface glycoprotein CD8 beta chain isoform 1 (human) http://purl.obolibrary.org/obo/PR_P10966 T-cell surface glycoprotein CD8 beta chain (human) A T-cell surface glycoprotein CD8 beta chain isoform 1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0005377 olfactory bulb glomerular layer http://purl.obolibrary.org/obo/UBERON_0004001 olfactory bulb layer The glomerular layer is the most superficial layer, consisting of mitral cell dendritic arborizations (glomeruli), olfactory nerve fibers, and periglomerular cells. Periglomerular cells contact multiple mitral cell dendrites within the glomeruli and provide lateral inhibition of neighboring glomeruli while allowing excitation of a specific mitral cell dendritic tree. Each mitral cell is contacted by at least 1000 olfactory nerve fibers[BTO]. Portion of tissue which is located in between the primary olfactory fiber layer and the external cellular layer of the olfactory bulb[ZFA]. http://purl.obolibrary.org/obo/PR_P11087 collagen alpha-1(I) chain (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A collagen alpha-1(I) chain that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0005378 olfactory bulb granule cell layer http://purl.obolibrary.org/obo/UBERON_0004001 olfactory bulb layer The granule cell layer contains multiple small round neurons that lack axons. Long dendritic processes of the neurons reach the more superficial layers and inhibit mitral cells and tufted cells. Small distal processes make contacts with the exiting mitral cell axons. http://purl.obolibrary.org/obo/PR_P11161 E3 SUMO-protein ligase EGR2 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein An early growth response protein 2 that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0005381 dentate gyrus granule cell layer http://purl.obolibrary.org/obo/UBERON_0002304 layer of dentate gyrus Granule cell layer is also called the DG principal cell layer. This one of the three layers of dentate gyrus that lies deep to the molecular layer and is made of densely packed layer that is four to eight granule cells thick. http://purl.obolibrary.org/obo/PR_P11247 myeloperoxidase (mouse) http://purl.obolibrary.org/obo/PR_000010543 myeloperoxidase A myeloperoxidase that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0005382 dorsal striatum http://purl.obolibrary.org/obo/UBERON_0011300 gray matter of telencephalon Dorsal components of the striatum comprising the caudate nucleus and the putamen, in species that have distinct nuclei; the caudoputamen in species which don't. http://purl.obolibrary.org/obo/PR_P11609 antigen-presenting glycoprotein CD1d1 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein An antigen-presenting glycoprotein CD1d that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0005383 caudate-putamen http://purl.obolibrary.org/obo/UBERON_0011215 central nervous system cell part cluster Regional part of telencephalon in some species, e.g., rodent, equivalent to the dorsal striatum (caudate nucleus and putamen). Unlike the dorsal striatum of primates, for example, the caudoputamen is not split into separate nuclei by the fibers of the internal capsule. Rather, the internal capsule splits into fiber bundles which course through the structure. http://purl.obolibrary.org/obo/PR_P11672 neutrophil gelatinase-associated lipocalin (mouse) http://purl.obolibrary.org/obo/PR_000009725 neutrophil gelatinase-associated lipocalin A neutrophil gelatinase-associated lipocalin that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0005384 nasal cavity epithelium http://purl.obolibrary.org/obo/UBERON_0019306 nose epithelium An epithelium that lines the nasal cavity. http://purl.obolibrary.org/obo/PR_P11678 eosinophil peroxidase (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein An eosinophil peroxidase that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0005385 nasal cavity respiratory epithelium http://purl.obolibrary.org/obo/UBERON_0005384 nasal cavity epithelium An epithelium that is part of the respiratory segment of the nasal mucosa [Automatically generated definition]. http://purl.obolibrary.org/obo/PR_P11684 uteroglobin (human) http://purl.obolibrary.org/obo/PR_000014505 uteroglobin A uteroglobin that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0005386 olfactory segment of nasal mucosa http://purl.obolibrary.org/obo/UBERON_0001826 nasal cavity mucosa That portion of the nasal mucosa containing the sensory endings for olfaction; the organ of smell[MESH]. http://purl.obolibrary.org/obo/PR_P11836 B-lymphocyte antigen CD20 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A membrane-spanning 4-domains subfamily A member 1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0005388 photoreceptor array http://purl.obolibrary.org/obo/UBERON_0004923 organ component layer An array of photoreceptors and any supporting cells found in an eye. http://purl.obolibrary.org/obo/PR_P12018 immunoglobulin iota chain (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein An immunoglobulin iota chain that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0005389 transparent eye structure http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure A transparent structure that is part of a visual sense organ, the function of which is to direct or focus light onto a photoreceptor array. http://purl.obolibrary.org/obo/PR_P12036 neurofilament heavy polypeptide (human) http://purl.obolibrary.org/obo/PR_000011118 neurofilament heavy polypeptide A neurofilament heavy polypeptide that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0005390 cortical layer I http://purl.obolibrary.org/obo/UBERON_0002301 layer of neocortex The most superficial layer of the neocortex characterized by a paucity of cell bodies. http://purl.obolibrary.org/obo/PR_P12272 parathyroid hormone-related protein (human) http://purl.obolibrary.org/obo/PR_000013433 parathyroid hormone-related protein A parathyroid hormone-related protein that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0005391 cortical layer II http://purl.obolibrary.org/obo/UBERON_0002301 layer of neocortex Layer of neocortex lying just deep to molecular layer characterized by numerous small cell bodies. http://purl.obolibrary.org/obo/PR_P12724 eosinophil cationic protein (human) http://purl.obolibrary.org/obo/PR_000014047 eosinophil cationic protein An eosinophil cationic protein that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0005392 cortical layer III http://purl.obolibrary.org/obo/UBERON_0002301 layer of neocortex Layer of neocortex lying deep to the external granule cell layer defined cytoarchitecturally by numerous small pyramidal neurons. http://purl.obolibrary.org/obo/PR_P12830 cadherin-1 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A cadherin-1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0005393 cortical layer IV http://purl.obolibrary.org/obo/UBERON_0002301 layer of neocortex Layer of neocortex lying deep to the external pyramidal cell layer defined cytoarchitecturally by the presence of numerous small cells. http://purl.obolibrary.org/obo/PR_P13379 T-cell surface glycoprotein CD5 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A T-cell surface glycoprotein CD5 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0005394 cortical layer V http://purl.obolibrary.org/obo/UBERON_0002301 layer of neocortex Layer of neocortex lying deep to the internal granule cell layer (layer 4) defined cytoarchitecturally by the predominance of large pyramidal cell bodies. http://purl.obolibrary.org/obo/PR_P13595 neural cell adhesion molecule 1 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A neural cell adhesion molecule 1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0005395 cortical layer VI http://purl.obolibrary.org/obo/UBERON_0002301 layer of neocortex Innermost layer of neocortex lying deep to the internal pyramidal cell layer defined cytoarchitecturally by cells of varying size. http://purl.obolibrary.org/obo/PR_P13727 bone marrow proteoglycan (human) http://purl.obolibrary.org/obo/PR_000013206 bone marrow proteoglycan A bone marrow proteoglycan that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0005397 brain arachnoid mater http://purl.obolibrary.org/obo/UBERON_0003547 brain meninx An arachnoid mater that surrounds a brain. http://purl.obolibrary.org/obo/PR_P13727-1 bone marrow proteoglycan isoform 1 (human) http://purl.obolibrary.org/obo/PR_P13727 bone marrow proteoglycan (human) A bone marrow proteoglycan isoform 1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0005398 female reproductive gland http://purl.obolibrary.org/obo/UBERON_0003937 reproductive gland A sex gland that is part of a female reproductive system. http://purl.obolibrary.org/obo/PR_P14136 glial fibrillary acidic protein (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A glial fibrillary acidic protein that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0005399 male reproductive gland http://purl.obolibrary.org/obo/UBERON_0003937 reproductive gland A sex gland that is part of a male reproductive system. http://purl.obolibrary.org/obo/PR_P14151 L-selectin (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein An L-selectin that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0005400 telencephalon arachnoid mater http://purl.obolibrary.org/obo/UBERON_0003556 forebrain arachnoid mater An arachnoid mater that is part of a telencephalon. http://purl.obolibrary.org/obo/PR_P14211 calreticulin (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A calreticulin that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0005401 cerebral hemisphere gray matter http://purl.obolibrary.org/obo/UBERON_0011300 gray matter of telencephalon A gray matter that is part of a cerebral hemisphere. http://purl.obolibrary.org/obo/PR_P14222 perforin-1 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A perforin-1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0005403 ventral striatum http://purl.obolibrary.org/obo/UBERON_0011300 gray matter of telencephalon A composite structure of the telencephalon that is defined in the striatopallidal system by connectivity and neurochemical staining. It includes the nucleus accumbens, the most ventral portions of the caudate nucleus and the putamen, the rostrolateral portion of the anterior perforated substance, the islands of Calleja and a rostral subcommissural portion of substantia innominata. The boundary between the ventral striatum and dorsal striatum is indistinct in sections stained for Nissl substance (Heimer-1995; adapted from Brain Info). http://purl.obolibrary.org/obo/PR_P14416 D(2) dopamine receptor (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A D(2) dopamine receptor that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0005406 perirenal fat http://purl.obolibrary.org/obo/UBERON_0001013 adipose tissue The adipose capsule of kidney (or perinephric fat or perirenal fat) is a structure between the renal fascia and renal capsule, and may be regarded as a part of the latter. A different structure, the pararenal fat, is the adipose tissue superficial to the renal fascia. http://purl.obolibrary.org/obo/PR_P14719 interleukin-1 receptor-like 1 (mouse) http://purl.obolibrary.org/obo/PR_000008994 interleukin-1 receptor-like 1 An interleukin-1 receptor-like 1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0005407 sublingual ganglion http://purl.obolibrary.org/obo/UBERON_0001808 parasympathetic ganglion The small parasympathetic ganglion found anterior to the submandibular gland that provides postsynaptic fibers to the sublingual gland. http://purl.obolibrary.org/obo/PR_P15306 thrombomodulin (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A thrombomodulin that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0005408 circumventricular organ http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain Any of any of the secretory or sensory organs located in the brain region around or in relation to the ventricular system that are characterized by extensive vasculature and a lack of a normal blood brain barrier (BBB) and allow for the linkage between the central nervous system and peripheral blood flow. http://purl.obolibrary.org/obo/PR_P15331 peripherin (mouse) http://purl.obolibrary.org/obo/PR_000013289 peripherin A peripherin that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0005410 cartilaginous otic capsule http://purl.obolibrary.org/obo/UBERON_0004637 otic capsule An otic capsule endochondral element that is composed primarily of cartilage tissue. http://purl.obolibrary.org/obo/PR_P15379 CD44 antigen (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A CD44 molecule that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0005411 bony otic capsule http://purl.obolibrary.org/obo/UBERON_0011164 neurocranium bone The cartilage or bony capsule surrounding the inner ear mechanism. http://purl.obolibrary.org/obo/PR_P15655 fibroblast growth factor 2 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A fibroblast growth factor 2 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0005417 forelimb bud http://purl.obolibrary.org/obo/UBERON_0005419 pectoral appendage bud A limb bud that develops into a forelimb. http://purl.obolibrary.org/obo/PR_P15702 leukosialin (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A leukosialin that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0005418 hindlimb bud http://purl.obolibrary.org/obo/UBERON_0005420 pelvic appendage bud A limb bud that develops into a hindlimb. http://purl.obolibrary.org/obo/PR_P15814 immunoglobulin lambda-like polypeptide 1 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein An immunoglobulin lambda-like polypeptide 1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P15918 V(D)J recombination-activating protein 1 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A V(D)J recombination-activating protein 1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0005419 pectoral appendage bud http://purl.obolibrary.org/obo/UBERON_0004357 paired limb/fin bud A limb bud that develops into a forelimb or pectoral fin. http://purl.obolibrary.org/obo/PR_P15919 V(D)J recombination-activating protein 1 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A V(D)J recombination-activating protein 1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0005420 pelvic appendage bud http://purl.obolibrary.org/obo/UBERON_0004357 paired limb/fin bud A limb bud that develops into a hindlimb or pelvic fin. http://purl.obolibrary.org/obo/PR_P15976 erythroid transcription factor (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein An erythroid transcription factor that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0005421 pectoral appendage apical ectodermal ridge http://purl.obolibrary.org/obo/UBERON_0004356 apical ectodermal ridge An apical ectodermal ridge that is part of a pectoral appendage bud. http://purl.obolibrary.org/obo/PR_P16015 carbonic anhydrase 3 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A carbonic anhydrase 3 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0005422 pelvic appendage apical ectodermal ridge http://purl.obolibrary.org/obo/UBERON_0004356 apical ectodermal ridge An apical ectodermal ridge that is part of a pelvic appendage bud. http://purl.obolibrary.org/obo/PR_P16045 galectin-1 (mouse) http://purl.obolibrary.org/obo/PR_000009766 galectin-1 A galectin-1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0005424 presumptive retinal pigmented epithelium http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure Portion of tissue that is the outer layer of the optic cup and will become the retinal pigmented epithelium. http://purl.obolibrary.org/obo/PR_P48318 glutamate decarboxylase 1 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A glutamate decarboxylase 1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0005425 presumptive neural retina http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure Portion of tissue that is the inner layer of the optic cup and will become the neural retina. http://purl.obolibrary.org/obo/PR_P48431 transcription factor SOX-2 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A transcription factor SOX-2 that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0005426 lens vesicle http://purl.obolibrary.org/obo/UBERON_0000479 tissue Portion of tissue that gives rise to the lens. http://purl.obolibrary.org/obo/PR_P48432 transcription factor SOX-2 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A transcription factor SOX-2 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0005427 corneal primordium http://purl.obolibrary.org/obo/UBERON_0010313 neural crest-derived structure Portion of tissue that is part of the eye and gives rise to the mature, fully layered cornea. http://purl.obolibrary.org/obo/PR_P49238 CX3C chemokine receptor 1 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A CX3C chemokine receptor 1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0005428 vagal neural crest http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue Vagal neural crest is adjacent to the first seven somites gives rise to both ganglionic and ectomesenchymal derivatives[ZFA]. http://purl.obolibrary.org/obo/PR_P49290 eosinophil peroxidase (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein An eosinophil peroxidase that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0005432 aortic sac http://purl.obolibrary.org/obo/UBERON_0003498 heart blood vessel The dilated structure that is lined by endothelial cells and located at the arterial pole of the heart just above (distal to) the truncus arteriosus in mammalian embryos; it is the primordial vascular channel from which the aortic arches (and eventually the dorsal aortae) arise; the aortic sac is homologous to the ventral aorta of gill-bearing vertebrates. http://purl.obolibrary.org/obo/PR_P49582 neuronal acetylcholine receptor subunit alpha-7 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A neuronal acetylcholine receptor subunit alpha-7 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0005436 common hepatic artery http://purl.obolibrary.org/obo/UBERON_0004573 systemic artery In anatomy, the common hepatic artery is a short blood vessel that supplies oxygenated blood to the liver, pylorus (a part of the stomach), duodenum (a part of the small intestine), pancreas, and gall bladder. It arises from the celiac artery and has the following branches: the hepatic artery proper, the gastroduodenal artery and the right gastric artery. http://purl.obolibrary.org/obo/PR_P49682 C-X-C chemokine receptor type 3 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A C-X-C chemokine receptor type 3 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P49863 granzyme K (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A granzyme K that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0005445 segment of pes http://purl.obolibrary.org/obo/UBERON_0012139 segment of autopod A segment of autopod that is part of a pes. http://purl.obolibrary.org/obo/PR_P49961 ectonucleoside triphosphate diphosphohydrolase 1 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein An ectonucleoside triphosphate diphosphohydrolase 1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0005446 foramen rotundum http://purl.obolibrary.org/obo/UBERON_0013685 foramen of skull The foramen rotundum is a circular hole in the sphenoid bone that connects the middle cranial fossa and the pterygopalatine fossa. http://purl.obolibrary.org/obo/PR_P50114 protein S100-B (mouse) http://purl.obolibrary.org/obo/PR_000014419 protein S100-B A protein S100-B that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0005451 segment of manus http://purl.obolibrary.org/obo/UBERON_0012139 segment of autopod A segment of autopod that is part of a manus. http://purl.obolibrary.org/obo/PR_P50220 homeobox protein Nkx-2.1 (mouse) http://purl.obolibrary.org/obo/PR_000011241 homeobox protein Nkx-2.1 A homeobox protein Nkx-2.1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0005453 inferior mesenteric ganglion http://purl.obolibrary.org/obo/UBERON_0035769 mesenteric ganglion A ganglion located near where the inferior mesenteric artery branches from the abdominal aorta[WP]. http://purl.obolibrary.org/obo/PR_P50283 T-cell antigen CD7 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A CD7 molecule that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0005457 left thymus lobe http://purl.obolibrary.org/obo/UBERON_0005483 thymus lobe A thymus lobe that is in the left side of a thymus. http://purl.obolibrary.org/obo/PR_P50481 LIM/homeobox protein Lhx3 (mouse) http://purl.obolibrary.org/obo/PR_000009793 LIM/homeobox protein Lhx3 A LIM/homeobox protein Lhx3 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0005459 left umbilical vein http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure An umbilical vein that is in the left side of a multicellular organism. http://purl.obolibrary.org/obo/PR_P51449 nuclear receptor ROR-gamma (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A nuclear receptor ROR-gamma that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0005460 left vitelline vein http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure A vitelline vein that is in the left side of a multicellular organism. http://purl.obolibrary.org/obo/PR_P51450 nuclear receptor ROR-gamma (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A nuclear receptor ROR-gamma that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0005461 levator scapulae muscle http://purl.obolibrary.org/obo/UBERON_0034908 scapular muscle An axial muscle that originates in the cervical vertebraae inserts on the scapula. http://purl.obolibrary.org/obo/PR_P51450-2 nuclear receptor ROR-gamma isoform 2 (mouse) http://purl.obolibrary.org/obo/PR_P51450 nuclear receptor ROR-gamma (mouse) A nuclear receptor ROR-gamma isoform 2 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0005462 lower back http://purl.obolibrary.org/obo/UBERON_0009569 subdivision of trunk Subdivision of abdominal segment of trunk which in humans is demarcated from the front of the abdomen by the posterior surface of the anterior layer of the thoracolumbar fascia and the anterior surface of the lumbar vertebral column; together with the front of the abdomen, it constitutes the abdomen[Modified from FMA]. http://purl.obolibrary.org/obo/PR_P51675 C-C chemokine receptor type 1 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A C-C chemokine receptor type 1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0005463 subcapsular sinus of lymph node http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space A space between the capsule and the cortex which allows the free movement of lymphatic fluid and so contains a sparsity of lymphocytes. It is continuous with the similar lymph sinuses that flank the trabeculae. http://purl.obolibrary.org/obo/PR_P51677 C-C chemokine receptor type 3 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A C-C chemokine receptor type 3 that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0005469 right thymus lobe http://purl.obolibrary.org/obo/UBERON_0005483 thymus lobe A thymus lobe that is in the right side of a thymus. http://purl.obolibrary.org/obo/PR_P51678 probable C-C chemokine receptor type 3 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A C-C chemokine receptor type 3 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0005471 right umbilical vein http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure An umbilical vein that is in the right side of a multicellular organism. http://purl.obolibrary.org/obo/PR_P51679 C-C chemokine receptor type 4 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A C-C chemokine receptor type 4 that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0005472 right vitelline vein http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure A vitelline vein that is in the right side of a multicellular organism. http://purl.obolibrary.org/obo/PR_P51680 C-C chemokine receptor type 4 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A C-C chemokine receptor type 4 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0005473 sacral region http://purl.obolibrary.org/obo/UBERON_0011676 subdivision of organism along main body axis A subdivision of an organism along the anterior-posterior axis in the pelvic region immediately posterior to the lumbar region and anterior to the caudal region. Sometimes an intermediate region is defined between the sacral and caudal. http://purl.obolibrary.org/obo/PR_P51681 C-C chemokine receptor type 5 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A C-C chemokine receptor type 5 that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0005476 spinal nerve trunk http://purl.obolibrary.org/obo/UBERON_0002464 nerve trunk Trunk part of spinal nerve, where dorsal and ventral roots meet to form the spinal nerve, before branching off to dorsal and ventral rami. http://purl.obolibrary.org/obo/PR_P51682 C-C chemokine receptor type 5 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A C-C chemokine receptor type 5 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0005477 stomach fundus epithelium http://purl.obolibrary.org/obo/UBERON_0001276 epithelium of stomach A simple columnar epithelium that is part of a fundus of stomach. http://purl.obolibrary.org/obo/PR_P51683 C-C chemokine receptor type 2 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A C-C chemokine receptor type 2 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0005478 sulcus limitans of neural tube http://purl.obolibrary.org/obo/UBERON_0006846 surface groove A longitudinal groove in the neural tube wall that divides the neural tube into dorsal (alar) and ventral (basal) halves (dorsal receives input from sensory neurons, ventral effects motor functions); stretches from the mesencephalon caudad[TMD]. http://purl.obolibrary.org/obo/PR_P51684 C-C chemokine receptor type 6 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A C-C chemokine receptor type 6 that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0005479 superior mesenteric ganglion http://purl.obolibrary.org/obo/UBERON_0035769 mesenteric ganglion A ganglion in the upper part of the superior mesenteric plexus that is the synapsing point for one of the pre- and post-synaptic nerves of the sympathetic division of the autonomous nervous system. http://purl.obolibrary.org/obo/PR_P51885 lumican (mouse) http://purl.obolibrary.org/obo/PR_000009981 lumican A lumican that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0005483 thymus lobe http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure Either of the two lateral lobes that constitute the thymus. http://purl.obolibrary.org/obo/PR_P53566 CCAAT/enhancer-binding protein alpha (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A CCAAT/enhancer-binding protein alpha that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0005486 venous dural sinus http://purl.obolibrary.org/obo/UBERON_0006615 venous sinus A venous channel found between layers of dura mater in the brain. Receives blood from internal and external veins of the brain, receive cerebrospinal fluid (CSF) from the subarachnoid space, and ultimately empty into the internal jugular vein. http://purl.obolibrary.org/obo/PR_Q2VLH6 scavenger receptor cysteine-rich type 1 protein M130 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A scavenger receptor cysteine-rich type 1 protein M130 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0005487 vitelline vein http://purl.obolibrary.org/obo/UBERON_0013140 systemic vein The paired veins that carry blood from the yolk sac back to the embryo. http://purl.obolibrary.org/obo/PR_Q5UKY4 cell surface glycoprotein CD200 receptor 3 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A cell surface glycoprotein CD200 receptor 3 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0005488 superior mesenteric plexus http://purl.obolibrary.org/obo/UBERON_0000122 neuron projection bundle The superior mesenteric plexus is a continuation of the lower part of the celiac plexus, receiving a branch from the junction of the right vagus nerve with the plexus. It surrounds the superior mesenteric artery, accompanies it into the mesentery, and divides into a number of secondary plexuses, which are distributed to all the parts supplied by the artery, viz. , pancreatic branches to the pancreas; intestinal branches to the small intestine; and ileocolic, right colic, and middle colic branches, which supply the corresponding parts of the great intestine. The nerves composing this plexus are white in color and firm in texture; in the upper part of the plexus close to the origin of the superior mesenteric artery is the superior mesenteric ganglion. http://purl.obolibrary.org/obo/PR_Q60651 killer cell lectin-like receptor 4 (mouse) http://purl.obolibrary.org/obo/PR_000009619 killer cell lectin-like receptor 4 A killer cell lectin-like receptor 4 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0005491 glossopharyngeal neural crest http://purl.obolibrary.org/obo/UBERON_0003099 cranial neural crest Cranial neural crest which gives rise to the glossopharyngeal ganglion. http://purl.obolibrary.org/obo/PR_Q60677 integrin alpha-E (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein An integrin alpha-E that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0005496 neural tube lateral wall http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure Portion of tissue on the side of the lumen of the neural tube. http://purl.obolibrary.org/obo/PR_Q60682 killer cell lectin-like receptor 8 (mouse) http://purl.obolibrary.org/obo/PR_000009623 killer cell lectin-like receptor 8 A killer cell lectin-like receptor 8 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0005498 primitive heart tube http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure Multi-tissue structure that arises from the heart rudiment and will become the heart tube. http://purl.obolibrary.org/obo/PR_Q60754 macrophage receptor MARCO (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A macrophage receptor MARCO that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0005499 rhombomere 1 http://purl.obolibrary.org/obo/UBERON_0001892 rhombomere Hindbrain segment or neuromere 1. http://purl.obolibrary.org/obo/PR_Q60767 lymphocyte antigen 75 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A lymphocyte antigen 75 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0005501 rhombomere lateral wall http://purl.obolibrary.org/obo/UBERON_0005496 neural tube lateral wall A neural tube lateral wall that is part of a rhombomere. http://purl.obolibrary.org/obo/PR_Q60805 tyrosine-protein kinase Mer (mouse) http://purl.obolibrary.org/obo/PR_000010329 tyrosine-protein kinase Mer A tyrosine-protein kinase Mer that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0005562 thymus primordium http://purl.obolibrary.org/obo/UBERON_0003351 pharyngeal epithelium A small outgrowth of the pharyngeal epithelium that is the site of lymphocyte cell production[ZFA]. [PMID]. http://purl.obolibrary.org/obo/PR_Q60841 reelin (mouse) http://purl.obolibrary.org/obo/PR_000013879 reelin A reelin that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0005563 trigeminal neural crest http://purl.obolibrary.org/obo/UBERON_0007530 migrating mesenchyme population Cranial neural crest which gives rise to the trigeminal ganglion. http://purl.obolibrary.org/obo/PR_Q61176 arginase-1 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein An arginase-1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0005564 gonad primordium http://purl.obolibrary.org/obo/UBERON_0001048 primordium Portion of tissue that gives rise to the immature gonad. http://purl.obolibrary.org/obo/PR_Q61245 collagen alpha-1(XI) chain (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A collagen alpha-1(XI) chain that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0005565 facio-acoustic neural crest http://purl.obolibrary.org/obo/UBERON_0014387 mesenchyme derived from neural crest Cranial neural crest that gives rise to the facio-acoustic ganglion. http://purl.obolibrary.org/obo/PR_Q61391 neprilysin (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A neprilysin that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0005567 rhombomere 1 lateral wall http://purl.obolibrary.org/obo/UBERON_0005501 rhombomere lateral wall A rhombomere lateral wall that is part of a rhombomere 1. http://purl.obolibrary.org/obo/PR_Q61549 adhesion G protein-coupled receptor E1 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein An adhesion G protein-coupled receptor E1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0005568 rhombomere 1 roof plate http://purl.obolibrary.org/obo/UBERON_0005502 rhombomere roof plate A rhombomere roof plate that is part of a rhombomere 1. http://purl.obolibrary.org/obo/PR_Q61575 forkhead box protein N1 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A forkhead box protein N1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0005594 head somite http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue Somite located in the head region, caudal to the otic vesicle. http://purl.obolibrary.org/obo/PR_Q61616 D(1A) dopamine receptor (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A D(1A) dopamine receptor that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0005597 lung primordium http://purl.obolibrary.org/obo/UBERON_0001048 primordium A pair of lateral diverticula just over the liver rudiment representing the primordia of the lungs, formed by the floor of the foregut just anterior to the liver diverticulum. http://purl.obolibrary.org/obo/PR_Q61830 macrophage mannose receptor 1 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A macrophage mannose receptor 1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0005598 trunk somite http://purl.obolibrary.org/obo/UBERON_0002329 somite A somite that is part of a trunk. http://purl.obolibrary.org/obo/PR_Q61878 bone marrow proteoglycan (mouse) http://purl.obolibrary.org/obo/PR_000013206 bone marrow proteoglycan A bone marrow proteoglycan that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0005609 iliac artery http://purl.obolibrary.org/obo/UBERON_0004573 systemic artery Any of the arteries that arise from a bifurcation of the aorta supplying the pelvic or abdomen. Examples: Common iliac artery, External iliac artery, Internal iliac artery. http://purl.obolibrary.org/obo/PR_Q61878-1 bone marrow proteoglycan isoform 1 (mouse) http://purl.obolibrary.org/obo/PR_Q61878 bone marrow proteoglycan (mouse) A bone marrow proteoglycan isoform 1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0005614 lens anterior epithelium http://purl.obolibrary.org/obo/UBERON_0010371 ecto-epithelium A layer of cuboidal epithelial cells bounded anteriorly by the capsule of the lens and posteriorly by the lens cortex. http://purl.obolibrary.org/obo/PR_Q62009 periostin (mouse) http://purl.obolibrary.org/obo/PR_000013031 periostin A periostin that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0005616 mesenteric artery http://purl.obolibrary.org/obo/UBERON_0012254 abdominal aorta artery Arteries which arise from the abdominal aorta and distribute to most of the intestines. http://purl.obolibrary.org/obo/PR_Q8CG65 SCO-spondin (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A SCO-spondin that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0005617 mesenteric vein http://purl.obolibrary.org/obo/UBERON_0001638 vein A vein that returns blood from the intestines. http://purl.obolibrary.org/obo/PR_Q8CJ91 CD209 antigen-like protein B (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A CD209 molecule-like protein B that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0005624 suprarenal artery http://purl.obolibrary.org/obo/UBERON_0001637 artery Artery that supplies blood to the adrenal glands. http://purl.obolibrary.org/obo/PR_Q8WTT0 C-type lectin domain family 4 member C (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A C-type lectin domain family 4 member C that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0005625 tubotympanic recess lumen http://purl.obolibrary.org/obo/UBERON_0007473 lumen of epithelial sac The cavity formed by the tubotympanic recess epithelium. http://purl.obolibrary.org/obo/PR_Q920G3 sialic acid-binding Ig-like lectin 5 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A sialic acid-binding Ig-like lectin 5 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0005626 ventral mesogastrium http://purl.obolibrary.org/obo/UBERON_0003281 mesentery of stomach Portion of ventral mesentery closest to the stomach. http://purl.obolibrary.org/obo/PR_Q92954 proteoglycan 4 (human) http://purl.obolibrary.org/obo/PR_000013208 proteoglycan 4 A proteoglycan 4 that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0005629 vascular plexus http://purl.obolibrary.org/obo/UBERON_0002049 vasculature A vascular network formed by frequent anastomoses between the blood vessels (arteries or veins) of a part. http://purl.obolibrary.org/obo/PR_Q9JLV1 BAG family molecular chaperone regulator 3 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A BAG family molecular chaperone regulator 3 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0005631 extraembryonic membrane http://purl.obolibrary.org/obo/UBERON_0000158 membranous layer Intrinsic membrane that arises from embryonic germ layers and grow to surround the developing embryo. http://purl.obolibrary.org/obo/PR_Q9JM99 proteoglycan 4 (mouse) http://purl.obolibrary.org/obo/PR_000013208 proteoglycan 4 A proteoglycan 4 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0005636 caecum epithelium http://purl.obolibrary.org/obo/UBERON_0000397 colonic epithelium An epithelium that is part of a caecum. http://purl.obolibrary.org/obo/PR_Q9Y2I2 netrin-G1 (human) http://purl.obolibrary.org/obo/PR_000011467 netrin-G1 A netrin-G1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0005637 pyloric region epithelium http://purl.obolibrary.org/obo/UBERON_0001276 epithelium of stomach An epithelium that is part of a pylorus. http://purl.obolibrary.org/obo/PR_Q9Y5S1 transient receptor potential cation channel subfamily V member 2 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A transient receptor potential cation channel TRPV2 that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0005638 anterior chamber epithelium http://purl.obolibrary.org/obo/UBERON_0015808 eye epithelium An epithelium that is part of a anterior chamber of eyeball. http://purl.obolibrary.org/obo/PR_Q9Y5Y4 prostaglandin D2 receptor 2 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A prostaglandin D2 receptor DP2 that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0005656 lens vesicle epithelium http://purl.obolibrary.org/obo/UBERON_0000483 epithelium An epithelium that is part of a lens vesicle. http://purl.obolibrary.org/obo/UBERON_0005660 2nd arch ectoderm http://purl.obolibrary.org/obo/UBERON_0000924 ectoderm An ectoderm that is part of a pharyngeal arch 2. http://purl.obolibrary.org/obo/PR_Q9Y6W8 inducible T-cell costimulator (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein An inducible T-cell costimulator that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0005661 3rd arch ectoderm http://purl.obolibrary.org/obo/UBERON_0000924 ectoderm An ectoderm that is part of a pharyngeal arch 3. http://purl.obolibrary.org/obo/PR_Q9Z0D9 CX3C chemokine receptor 1 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A CX3C chemokine receptor 1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0005662 4th arch ectoderm http://purl.obolibrary.org/obo/UBERON_0000924 ectoderm An ectoderm that is part of a pharyngeal arch 4. http://purl.obolibrary.org/obo/PR_Q9Z0F7 gamma-synuclein (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A gamma-synuclein that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0005664 2nd arch endoderm http://purl.obolibrary.org/obo/UBERON_0000925 endoderm An endoderm that is part of a pharyngeal arch 2. http://purl.obolibrary.org/obo/PR_Q9Z0J4 nitric oxide synthase 1 (mouse) http://purl.obolibrary.org/obo/PR_000011326 nitric oxide synthase 1 A nitric oxide synthase 1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0005665 3rd arch endoderm http://purl.obolibrary.org/obo/UBERON_0000925 endoderm An endoderm that is part of a pharyngeal arch 3. http://purl.obolibrary.org/obo/PR_Q9Z2J6 prostaglandin D2 receptor 2 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A prostaglandin D2 receptor DP2 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0005666 4th arch endoderm http://purl.obolibrary.org/obo/UBERON_0000925 endoderm An endoderm that is part of a pharyngeal arch 4. http://purl.obolibrary.org/obo/UBERON_0005669 peritoneal cavity mesothelium http://purl.obolibrary.org/obo/UBERON_0001136 mesothelium A mesothelium that is part of a peritoneal cavity. http://purl.obolibrary.org/obo/UBERON_0005672 right lung endothelium http://purl.obolibrary.org/obo/UBERON_0003364 epithelium of right lung An endothelium that is part of a right lung. http://purl.obolibrary.org/obo/UBERON_0005673 left lung endothelium http://purl.obolibrary.org/obo/UBERON_0003365 epithelium of left lung An endothelium that is part of a left lung. http://purl.obolibrary.org/obo/UBERON_0005677 caecum mesentery http://purl.obolibrary.org/obo/UBERON_0003396 mesentery of colon A mesentery that is part of a caecum. http://purl.obolibrary.org/obo/UBERON_0005687 orbitosphenoid cartilage element http://purl.obolibrary.org/obo/UBERON_0015059 orbitosphenoid endochondral element An orbitosphenoid endochondral element that is composed primarily of cartilage tissue. http://purl.obolibrary.org/obo/UBERON_0005688 lens vesicle cavity http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space An anatomical cavity that is part of a lens vesicle. http://purl.obolibrary.org/obo/CL_0001065 innate lymphoid cell http://purl.obolibrary.org/obo/CL_0000542 lymphocyte A lymphocyte that lacks characteristic T cell, B cell, myeloid cell, and dendritic cell markers, that functions as part of the innate immune response to produce cytokines and other effector responses. http://purl.obolibrary.org/obo/UBERON_0005689 2nd arch mesenchyme http://purl.obolibrary.org/obo/UBERON_0009494 pharyngeal arch mesenchymal region Mesenchyme that is part of a pharyngeal arch 2. http://purl.obolibrary.org/obo/UBERON_0036214 rectosigmoid junction http://purl.obolibrary.org/obo/UBERON_8410024 intestinal junction An anatomical junction that is between the sigmoid colon and rectum. http://purl.obolibrary.org/obo/UBERON_0005690 3rd arch mesenchyme http://purl.obolibrary.org/obo/UBERON_0009494 pharyngeal arch mesenchymal region Mesenchyme that is part of a pharyngeal arch 3. http://purl.obolibrary.org/obo/GO_0140096 catalytic activity, acting on a protein http://purl.obolibrary.org/obo/GO_0003824 catalytic activity Catalytic activity that acts to modify a protein. http://purl.obolibrary.org/obo/UBERON_0005691 4th arch mesenchyme http://purl.obolibrary.org/obo/UBERON_0009494 pharyngeal arch mesenchymal region Mesenchyme that is part of a pharyngeal arch 4. http://purl.obolibrary.org/obo/GO_0140097 catalytic activity, acting on DNA http://purl.obolibrary.org/obo/GO_0140640 catalytic activity, acting on a nucleic acid Catalytic activity that acts to modify DNA. http://purl.obolibrary.org/obo/UBERON_0005702 optic eminence mesenchyme http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue Mesenchyme that is part of a optic eminence. http://purl.obolibrary.org/obo/GO_0140098 catalytic activity, acting on RNA http://purl.obolibrary.org/obo/GO_0140640 catalytic activity, acting on a nucleic acid Catalytic activity that acts to modify RNA. http://purl.obolibrary.org/obo/UBERON_0005711 foregut duodenum mesentery http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure A mesentery of duodenum that is part of a foregut. http://purl.obolibrary.org/obo/GO_0140101 catalytic activity, acting on a tRNA http://purl.obolibrary.org/obo/GO_0140098 catalytic activity, acting on RNA Catalytic activity that acts to modify a tRNA. http://purl.obolibrary.org/obo/UBERON_0005712 midgut duodenum mesentery http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure A mesentery of duodenum that is part of a midgut. http://purl.obolibrary.org/obo/GO_0140103 catalytic activity, acting on a glycoprotein http://purl.obolibrary.org/obo/GO_0140096 catalytic activity, acting on a protein Catalysis of a biochemical reaction in which one of the substrates is a glycoprotein. http://purl.obolibrary.org/obo/UBERON_0005719 footplate apical ectodermal ridge http://purl.obolibrary.org/obo/UBERON_0004356 apical ectodermal ridge An apical ectodermal ridge that is part of a footplate. http://purl.obolibrary.org/obo/GO_0106134 positive regulation of cardiac muscle cell contraction http://purl.obolibrary.org/obo/GO_1903116 positive regulation of actin filament-based movement Any process that activates or increases the frequency, rate or extent of cardiac muscle cell contraction. http://purl.obolibrary.org/obo/UBERON_0005720 hindbrain venous system http://purl.obolibrary.org/obo/UBERON_0004582 venous system A venous system that is part of a hindbrain. http://purl.obolibrary.org/obo/GO_0140375 immune receptor activity http://purl.obolibrary.org/obo/GO_0038023 signaling receptor activity Receiving a signal and transmitting it in a cell to initiate an immune response. http://purl.obolibrary.org/obo/UBERON_0005721 pronephric mesoderm http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure A mesoderm that has the potential to develop into a pronephros. http://purl.obolibrary.org/obo/GO_0140448 signaling receptor ligand precursor processing http://purl.obolibrary.org/obo/GO_0016485 protein processing The cleavage of a peptide bond in a precursor form of a signaling receptor ligand, resulting in the mature (active) form of the ligand. http://purl.obolibrary.org/obo/UBERON_0005723 floor plate spinal cord region http://purl.obolibrary.org/obo/UBERON_0003306 floor plate of neural tube A multi-tissue structure that is part of a spinal cord and is part of a floor plate. http://purl.obolibrary.org/obo/GO_0062236 ionocyte differentiation http://purl.obolibrary.org/obo/GO_0030855 epithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of an ionocyte. Ionocytes are specialized epithelial cells that contribute to osmotic homeostasis. http://purl.obolibrary.org/obo/UBERON_0005724 roof plate spinal cord region http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue A tissue that is part of a spinal cord and is part of a roof plate. http://purl.obolibrary.org/obo/GO_0062237 protein localization to postsynapse http://purl.obolibrary.org/obo/GO_0035418 protein localization to synapse Any process in which a protein is transported to, and/or maintained at the postsynapse, the part of a synapse that is part of the post-synaptic cell. http://purl.obolibrary.org/obo/UBERON_0005725 olfactory system http://purl.obolibrary.org/obo/UBERON_0005726 chemosensory system A sensory system that is capable of olfaction (the sensory perception of smell). http://purl.obolibrary.org/obo/PATO_0070013 spiny stellate cell morphology http://purl.obolibrary.org/obo/PATO_0070026 multipolar neuron morphology A cell morphology that inheres in neurons which have spiny basal dendrites and resemble pyramidal cells but lose their apical dendrites as they mature. Their axons nearly always emerge from the descending side of the soma, but often recurve and ascend with arc-like collaterals. http://purl.obolibrary.org/obo/UBERON_0005729 pectoral appendage field http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure A limb/fin field that has the potential to develop into a pectoral appendage bud mesenchyme. http://purl.obolibrary.org/obo/GO_0140640 catalytic activity, acting on a nucleic acid http://purl.obolibrary.org/obo/GO_0003824 catalytic activity Catalytic activity that acts to modify a nucleic acid. http://purl.obolibrary.org/obo/UBERON_0005730 pelvic appendage field http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure A limb/fin field that has the potential to develop into a pelvic appendage bud mesenchyme. http://purl.obolibrary.org/obo/GO_0140657 ATP-dependent activity http://purl.obolibrary.org/obo/GO_0003674 molecular_function A molecular function characterized by the coupling of ATP hydrolysis to other steps of a reaction mechanism to make the reaction energetically favorable, for example to catalyze a reaction or drive transport against a concentration gradient. http://purl.obolibrary.org/obo/UBERON_0005732 paired limb/fin field http://purl.obolibrary.org/obo/UBERON_0007688 anlage A ring of cells capable of forming a limb or paired fin[Gilbert,modified]. http://purl.obolibrary.org/obo/CL_4023089 nest basket cell http://purl.obolibrary.org/obo/CL_2000086 neocortex basket cell A basket cell which has simpler dendritic arbors (compared to small or large basket cells), and an axonal plexus of intermediate density, composed of a few long, smooth axonal branches. http://purl.obolibrary.org/obo/UBERON_0005733 limb field http://purl.obolibrary.org/obo/UBERON_0005732 paired limb/fin field A ring of cells capable of forming a limb. http://purl.obolibrary.org/obo/CL_4023051 vascular leptomeningeal cell http://purl.obolibrary.org/obo/CL_4023058 mesothelial fibroblast of the leptomeninx A transcriptomically distinct type of mesothelial fibroblast that is derived from the neural crest, is localized on blood vessels, and is a key component of the pia and arachnoid membranes surrounding the brain. The standard transcriptomic reference data for this cell type can be found on the CellxGene census under the collection: 'Transcriptomic cytoarchitecture reveals principles of human neocortex organization', dataset: 'Supercluster: Non-neuronal cells', Author Categories: 'CrossArea_subclass', clusters VLMC. http://purl.obolibrary.org/obo/UBERON_0005734 tunica adventitia of blood vessel http://purl.obolibrary.org/obo/UBERON_0005742 adventitia The outermost layer of a blood vessel, composed mainly of fibrous tissue. http://purl.obolibrary.org/obo/GO_0160024 Leydig cell proliferation http://purl.obolibrary.org/obo/GO_0008283 cell population proliferation The multiplication or reproduction of Leydig cells, resulting in the expansion of a cell population. Leydig cells are interstitial cells located adjacent to the seminiferous tubules in the testis which produce testosterone. http://purl.obolibrary.org/obo/UBERON_0005740 tunica intima of artery http://purl.obolibrary.org/obo/UBERON_0004797 blood vessel layer A tunica intima that is part of a artery. http://purl.obolibrary.org/obo/CL_0009105 T cell zone reticular cell http://purl.obolibrary.org/obo/CL_0009102 lymph node fibroblastic reticular cell A fibroblastic reticular cell found in the lymph node T cell domain. http://purl.obolibrary.org/obo/UBERON_0005742 adventitia http://purl.obolibrary.org/obo/UBERON_0004923 organ component layer An outermost connective tissue covering of an organ, vessel, or other structure[WP]. http://purl.obolibrary.org/obo/CL_0009109 lymphatic endothelial cell of trabecula http://purl.obolibrary.org/obo/CL_0009115 lymph node lymphatic vessel endothelial cell A lymphatic endothelial cell located in a lymph node trabecula. http://purl.obolibrary.org/obo/UBERON_0005744 bone foramen http://purl.obolibrary.org/obo/UBERON_0004111 anatomical conduit Anatomical space that is an opening in a bone, usually for passage of blood vessels or nerves. http://purl.obolibrary.org/obo/GO_0140820 cytosol to Golgi apparatus transport http://purl.obolibrary.org/obo/GO_0055085 transmembrane transport The directed movement of substances from the cytosol into the Golgi apparatus of a cell. http://purl.obolibrary.org/obo/UBERON_0005745 optic foramen http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure An opening in the skull through which cranial nerve II passes.[MP]. http://purl.obolibrary.org/obo/CL_0004219 A2 amacrine cell http://purl.obolibrary.org/obo/CL_4030028 glycinergic amacrine cell A bistratifed retinal amacrine cell with a small dendritic field, dendrite stratification in S1-S2, and a second dendrite stratification in S5. This cell type releases the neurotransmitter glycine. http://purl.obolibrary.org/obo/UBERON_0005749 glomerular tuft http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure The capillary loops of the kidney that normally function as a filtration unit[MP]. http://purl.obolibrary.org/obo/CL_0004245 indoleamine-accumulating amacrine cell http://purl.obolibrary.org/obo/CL_0004253 wide field retinal amacrine cell An amacrine cell with a wide dendritic field and post-synaptic terminals in S5. This cell type releases the neurotransmitters gamma-aminobutyric acid (GABA) and serotonin. http://purl.obolibrary.org/obo/UBERON_0005750 glomerular parietal epithelium http://purl.obolibrary.org/obo/UBERON_0004188 glomerular epithelium A single layer of simple squamous epithelium in the glomerular capsule. Does not function in filtration[UBERON]. outer layer of the glomerular capsule composed of a single layer of simple squamous epithelium[MP]. http://purl.obolibrary.org/obo/CL_0003006 G4-ON retinal ganglion cell http://purl.obolibrary.org/obo/CL_4023032 ON retinal ganglion cell A G4 retinal ganglion cell that has post sympatic terminals in sublaminar layers S3 and S4 and is depolarized by illumination of its receptive field center. http://purl.obolibrary.org/obo/UBERON_0005751 glomerular visceral epithelium http://purl.obolibrary.org/obo/UBERON_0004188 glomerular epithelium The inner (visceral) layer of the renal glomerular capsule, overlying the capillaries, composed of podocytes, and separated from the outer (parietal) layer by the capsular (Bowman's) space[BTO]. This epithelial layer is superficially adjacent to the thickened glomerular basement membrane and is made of podocytes. Beneath the visceral layer lie the glomerular capillaries[WP]. This inner epithelial layer of the glomerular capsule surrounds the capillary endothelial cells and is composed of highly specialized epithelial cells (podocytes) that are separated by filtration slits; the inner visceral layer is separated from the outer parietal layer by the urinary space (also known as the Bowman's or capsular space)[MP]. http://purl.obolibrary.org/obo/CL_0003049 M cone cell http://purl.obolibrary.org/obo/CL_0000573 retinal cone cell A cone cell that detects medium wavelength light. Exact peak of spectra detected differs between species. In humans, spectra peaks at 534-545 nm. http://purl.obolibrary.org/obo/UBERON_0005753 caudal part of nephrogenic cord http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure The metanephros develops from the most caudal part of the nephrogenic cord that is itself derived from the intermediate plate mesoderm. http://purl.obolibrary.org/obo/CL_0004217 H1 horizontal cell http://purl.obolibrary.org/obo/CL_0000745 retina horizontal cell A horizontal cell with a large cell body, thick dendrites, and a large dendritic arbor. http://purl.obolibrary.org/obo/UBERON_0005754 rostral part of nephrogenic cord http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure The initial renal anlage that develops from the most rostral part of the nephrogenic cord is termed the pronephros. http://purl.obolibrary.org/obo/CL_0004138 retinal ganglion cell A2 http://purl.obolibrary.org/obo/CL_0004117 alpha retinal ganglion cell (Mmus) A retinal ganglion A cell with dense arbor near soma. http://purl.obolibrary.org/obo/UBERON_0005760 urorectal septum http://purl.obolibrary.org/obo/UBERON_0003037 septum The ridge of mesoderm covered with endoderm that in the early developing embryo partitions the endodermal cloaca into the primary urogenital sinus (ventrally) and the anorectal canal of the hindgut (dorsally); the urorectal septum eventually fuses with the cloacal membrane, dividing it into a dorsal anal membrane and a larger ventral urogenital membrane - this area of fusion is represented in the adult by the perineal body[MP]. http://purl.obolibrary.org/obo/CL_0003040 M9 retinal ganglion cell http://purl.obolibrary.org/obo/CL_0000740 retinal ganglion cell A monostratified retinal ganglion cell with large soma and large dendritic field, with medium dendritic arbor, and has dendrites in layers 1 and 5. http://purl.obolibrary.org/obo/UBERON_0005764 acellular membrane http://purl.obolibrary.org/obo/UBERON_0000476 acellular anatomical structure An acellular anatomical structure that is the bounding layer of a anatomical structure. http://purl.obolibrary.org/obo/CL_0003020 retinal ganglion cell C outer http://purl.obolibrary.org/obo/CL_0004116 retinal ganglion cell C A retinal ganglion cell C that has post-synaptic terminals in S2. http://purl.obolibrary.org/obo/UBERON_0005769 basement membrane of epithelium http://purl.obolibrary.org/obo/UBERON_0005764 acellular membrane An acellular membrane that is part of the epithelium, lies adjacent to the epithelial cells, and is the fusion of the the basal lamina and the reticular lamina. http://purl.obolibrary.org/obo/CL_0004251 narrow field retinal amacrine cell http://purl.obolibrary.org/obo/CL_0000561 amacrine cell An amicrine that has a narrow dendritic field. http://purl.obolibrary.org/obo/UBERON_0005777 glomerular basement membrane http://purl.obolibrary.org/obo/UBERON_0005769 basement membrane of epithelium The layer of extracellular matrix that lies between the endothelium of the glomerular capillaries and the podocytes of the inner or visceral layer of the Bowman capsule; it is a fusion of the endothelial cell and podocyte basal laminas and acts as a physical barrier and an ion-selective filter. http://purl.obolibrary.org/obo/CL_0004237 fountain amacrine cell http://purl.obolibrary.org/obo/CL_0004252 medium field retinal amacrine cell A retinal amacrine cell with a medium dendritic field and post-synaptic terminals in S1, S2, S3, and S4. This cell type releases the neurotransmitter gamma-aminobutyric acid (GABA). http://purl.obolibrary.org/obo/UBERON_0005787 lamina densa of glomerular basement membrane http://purl.obolibrary.org/obo/UBERON_0005764 acellular membrane Middle layer of the glomerular basement membrane. http://purl.obolibrary.org/obo/CL_0004234 diffuse multistratified amacrine cell http://purl.obolibrary.org/obo/CL_0004252 medium field retinal amacrine cell An amacrine cell with a medium dendritic field and post-synaptic terminals in S2, and in S3-S4. http://purl.obolibrary.org/obo/UBERON_0005788 lamina rara interna http://purl.obolibrary.org/obo/UBERON_0000476 acellular anatomical structure Layer of the glomerular basement membrane adjacent to the glomerular capillary. http://purl.obolibrary.org/obo/CL_0003050 S cone cell http://purl.obolibrary.org/obo/CL_0000573 retinal cone cell A cone cell that detects short wavelength light. Exact peak of spectra detected differs between species. In humans, spectra peaks at 420-440 nm. http://purl.obolibrary.org/obo/UBERON_0005789 lamina rara externa http://purl.obolibrary.org/obo/UBERON_0000476 acellular anatomical structure Layer of the glomerular basement membrane adjacent to the podocytes and capsular space. http://purl.obolibrary.org/obo/CL_0003018 retinal ganglion cell B3 inner http://purl.obolibrary.org/obo/CL_0004183 retinal ganglion cell B3 A retinal ganglion B3 cell with dentrites terminating in S4. http://purl.obolibrary.org/obo/UBERON_0005792 nephric ridge http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure Nephric tubules (nephrons) form embryonically along the nephric ridge. The ridge comprises three regions; anterior, middle and posterior. The functional kidney uses nephrons from only one or two regions of the ridge. A pronephric kidney uses only the nephrons from the anterior region of the ridge. A mesonephric kidney uses only the middle region, a metanephric kidney uses only the posterior region and an opisthonephric kidney uses the middle and posterior regions. http://purl.obolibrary.org/obo/CL_0003034 M5 retinal ganglion cell http://purl.obolibrary.org/obo/CL_0000740 retinal ganglion cell A monostratified retinal ganglion cell that has a small soma, an assymetric dendritic field with post synaptic terminals in sublaminar layer S3. http://purl.obolibrary.org/obo/UBERON_0005800 section of aorta http://purl.obolibrary.org/obo/UBERON_0013522 subdivision of tube Any portion of the aorta including the ascending and descending aorta, and aortic arch or a portion of the aortic orifice of the left ventricle. http://purl.obolibrary.org/obo/CL_0004183 retinal ganglion cell B3 http://purl.obolibrary.org/obo/CL_0004115 retinal ganglion cell B A monostratified retinal ganglion cell with medium soma, sparse dendritic tree, and medium dendritic field. http://purl.obolibrary.org/obo/UBERON_0005805 dorsal aorta http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure The dorsal aorta is a blood vessel in a single-pass circulatory system that carries oxygenated blood from the gills to the rest of the body. In a single-pass circulatory system blood passes once through the heart to supply the body once. http://purl.obolibrary.org/obo/CL_0003037 M7-ON retinal ganglion cell http://purl.obolibrary.org/obo/CL_4023032 ON retinal ganglion cell An M7 retinal ganglion cells with synaptic terminals in S4 and is depolarized by illumination of its receptive field center. http://purl.obolibrary.org/obo/UBERON_0005806 portal system http://purl.obolibrary.org/obo/UBERON_0002049 vasculature In the circulatory system of animals, a portal venous system occurs when a capillary bed drains into another capillary bed through veins, without first going through the heart. Both capillary beds and the blood vessels that connect them are considered part of the portal venous system. They are relatively uncommon as the majority of capillary beds drain into veins which then drain into the heart, not into another capillary bed. Portal venous systems are considered venous because the blood vessels that join the two capillary beds are either veins or venules. Examples of such systems include the hepatic portal system and the hypophyseal portal system. Unqualified, 'portal venous system' often refers to the hepatic portal system. For this reason, 'portal vein' most commonly refers to the hepatic portal vein[WP]. http://purl.obolibrary.org/obo/CL_4023026 direct pathway medium spiny neuron http://purl.obolibrary.org/obo/CL_1001474 medium spiny neuron A GABAergic medium spiny neuron located in the striatum that gives rise to the direct basal ganglia pathway. It projects directly to the GPi and SNr, where it inhibits tonically active GABAergic output neurons to disinhibit thalamic and brainstem motor targets (Gerfen. 2023). In mice and humans, this cell selectively expresses the D1 dopamine receptor (DRD1), which couples to stimulatory G-proteins (Gs/Gαolf) to increase cAMP and activate PKA-dependent signaling cascades (Gerfen et al., 1990; Kebabian & Calne, 1979). Functionally, activation of this cell promotes selected motor actions by disinhibiting thalamic and midbrain motor centers (Mink, 1996; Cui et al., 2013). http://purl.obolibrary.org/obo/UBERON_0005808 bone tissue of long bone http://purl.obolibrary.org/obo/UBERON_0002481 bone tissue A bone tissue that is part of a long bone. http://purl.obolibrary.org/obo/CL_4030030 peripheral blood lymphocyte http://purl.obolibrary.org/obo/CL_4030029 blood lymphocyte A blood lymphocyte located in the flowing, circulating blood of the body. http://purl.obolibrary.org/obo/UBERON_0005809 cortex of manus bone http://purl.obolibrary.org/obo/UBERON_0003598 manus connective tissue The outer or sperficial part of a bone of the manus. http://purl.obolibrary.org/obo/CL_4033000 endothelial cell of venule of lymph node http://purl.obolibrary.org/obo/CL_1000414 endothelial cell of venule A(n) endothelial cell that is part of a(n) venule of lymph node. http://purl.obolibrary.org/obo/UBERON_0005813 tubercle http://purl.obolibrary.org/obo/UBERON_0004529 anatomical projection A round nodule, small eminence, or warty outgrowth on an anatomical surface, such as bones, skin, or within the lungs (in the case of tuberculosis). They are also found on the leading edge of Humpback Whale's flippers, improving fluid flow over the flipper's surface[WP]. http://purl.obolibrary.org/obo/UBERON_8600004 visceral muscle tissue http://purl.obolibrary.org/obo/UBERON_0002385 muscle tissue A muscle tissue that is associated with soft internal organs (viscera). http://purl.obolibrary.org/obo/UBERON_0005814 arch of atlas http://purl.obolibrary.org/obo/UBERON_0010358 arch of centrum of vertebra A vertebral arch that is part of the first cervical vertebra. http://purl.obolibrary.org/obo/UBERON_0005837 fasciculus of spinal cord http://purl.obolibrary.org/obo/UBERON_0011215 central nervous system cell part cluster A fascicle that is part of a spinal cord. http://purl.obolibrary.org/obo/CL_4033023 airway submucosal gland collecting duct epithelial cell http://purl.obolibrary.org/obo/CL_0000066 epithelial cell An epithelial cell that is part of a collecting duct of an airway submucosal gland. http://purl.obolibrary.org/obo/UBERON_0005838 fasciculus of brain http://purl.obolibrary.org/obo/UBERON_0011215 central nervous system cell part cluster A fascicle that is part of a brain. http://purl.obolibrary.org/obo/CL_4033025 perichondrial fibroblast http://purl.obolibrary.org/obo/CL_0000057 fibroblast A fibroblast that is part of the fibrous layer of the perichondrium. This cell is responsible for collagen fiber production. http://purl.obolibrary.org/obo/UBERON_0005843 sacral spinal cord http://purl.obolibrary.org/obo/UBERON_0005844 spinal cord segment A spinal cord segment that adjacent_to a sacral region. http://purl.obolibrary.org/obo/CL_4033019 ON-blue cone bipolar cell http://purl.obolibrary.org/obo/CL_0000749 ON-bipolar cell An ON bipolar cell type with dendrites selectively contacting S-cones. http://purl.obolibrary.org/obo/UBERON_0005845 caudal segment of spinal cord http://purl.obolibrary.org/obo/UBERON_0005844 spinal cord segment A spinal cord segment that adjacent_to a caudal region. http://purl.obolibrary.org/obo/CL_4033018 lung megakaryocyte http://purl.obolibrary.org/obo/CL_0002320 connective tissue cell A megakaryocyte that is resident in the lung connective tissue. http://purl.obolibrary.org/obo/UBERON_0005856 developing mesenchymal condensation http://purl.obolibrary.org/obo/UBERON_0011585 cell condensation A delimited region of dense mesenchyme within looser mesenchyme. http://purl.obolibrary.org/obo/CL_4033026 lung perichondrial fibroblast http://purl.obolibrary.org/obo/CL_4033025 perichondrial fibroblast A perichondrial fibroblast that is part of the lung. http://purl.obolibrary.org/obo/UBERON_0005863 cartilaginous condensation http://purl.obolibrary.org/obo/UBERON_0005856 developing mesenchymal condensation Cell condensation that is an aggregation of mesenchymal cells that are committed to differentiate into chondroblasts and chondrocytes. http://purl.obolibrary.org/obo/GO_0141067 intracellular nitrogen homeostasis http://purl.obolibrary.org/obo/GO_0055082 intracellular chemical homeostasis A homeostatic process involved in the maintenance of a steady state level of nitrogen within a cell. http://purl.obolibrary.org/obo/UBERON_0005866 pre-cartilage condensation http://purl.obolibrary.org/obo/UBERON_0005856 developing mesenchymal condensation A delimited region of dense mesenchyme within looser mesenchyme whose cells are committed to become chondroblasts. http://purl.obolibrary.org/obo/CL_4033046 ON midget ganglion cell http://purl.obolibrary.org/obo/CL_4023032 ON retinal ganglion cell A midget ganglion cell that depolarizes in response to increased light intensity in the center of its receptive field. The majority of input that this cell receives comes from invaginating midget bipolar cells. http://purl.obolibrary.org/obo/CL_4033047 OFF midget ganglion cell http://purl.obolibrary.org/obo/CL_4023188 midget ganglion cell of retina A midget ganglion cell that depolarizes in response to decreased light intensity in the center of its receptive field. The majority of input that this cell receives comes from flat midget bipolar cells. http://purl.obolibrary.org/obo/UBERON_0005867 mandibular prominence http://purl.obolibrary.org/obo/UBERON_0012314 embryonic facial prominence The paired ventral prominences formed by bifurcation of the first pharyngeal arches in the embryo; the two prominences unite ventrally and fuse to form the mandible and lower lip. http://purl.obolibrary.org/obo/CL_4033051 OFF parasol ganglion cell http://purl.obolibrary.org/obo/CL_4023189 parasol ganglion cell of retina A parasol ganglion cell that depolarizes in response to decreased light intensity in the center of its receptive field. The majority of input that this cell receives comes from DB3a bipolar cells. http://purl.obolibrary.org/obo/UBERON_0005868 maxillary prominence http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure The paired dorsal prominences formed by bifurcation of the first pharyngeal arches in the embryo that unite with the ipsilateral medial nasal process to form the upper jaw. http://purl.obolibrary.org/obo/CL_4033052 ON parasol ganglion cell http://purl.obolibrary.org/obo/CL_4023032 ON retinal ganglion cell A parasol ganglion cell that depolarizes in response to increased light intensity in the center of its receptive field. The majority of input that this cell receives comes from DB4 bipolar cells. http://purl.obolibrary.org/obo/UBERON_0005870 olfactory pit http://purl.obolibrary.org/obo/UBERON_0016566 pit An indentation of the olfactory placode which ends when the pits hollows out to form the nasopharynx[GO]. http://purl.obolibrary.org/obo/CL_4033053 small bistratified retinal ganglion cell http://purl.obolibrary.org/obo/CL_0003001 bistratified retinal ganglion cell A bistratfied retinal ganglion cell with a small dendritic field that has dendrites in the ON and OFF sublamina of the retinal inner plexiform layer and carries blue-ON/yellow-OFF signals. This cell receives bipolar and amacrine input to both the OFF and ON dendritic tree. http://purl.obolibrary.org/obo/UBERON_0005873 2nd arch pharyngeal cleft http://purl.obolibrary.org/obo/UBERON_0005879 pharyngeal cleft A groove that is situated between the 2nd and 3rd pharyngeal arch. http://purl.obolibrary.org/obo/CL_4033054 perivascular cell http://purl.obolibrary.org/obo/CL_0000000 cell A cell that is adjacent to a vessel. A perivascular cell plays a crucial role in maintaining vascular function and tissue homeostasis. This cell type regulates vessel integrity and flow dynamics. http://purl.obolibrary.org/obo/UBERON_0005874 3rd arch pharyngeal cleft http://purl.obolibrary.org/obo/UBERON_0005879 pharyngeal cleft A groove that is situated between the 3rd and 4th pharyngeal arch. http://purl.obolibrary.org/obo/CL_4033055 airway submucosal gland duct multiciliated cell http://purl.obolibrary.org/obo/CL_0005012 multiciliated epithelial cell A multi-ciliated epithelial cell located in ciliated duct of an airway submucosal gland, characterized by a columnar shape and motile cilia on its apical surface. http://purl.obolibrary.org/obo/CL_4040004 mesenchymal stem cell of orbital adipose tissue http://purl.obolibrary.org/obo/CL_0002570 mesenchymal stem cell of adipose tissue Any mesenchymal stem cell of adipose tissue that is part of an orbital region. http://purl.obolibrary.org/obo/UBERON_0005875 4th arch pharyngeal cleft http://purl.obolibrary.org/obo/UBERON_0005879 pharyngeal cleft A groove that is situated between the 4th and 5th pharyngeal arch. http://purl.obolibrary.org/obo/GO_0170034 L-amino acid biosynthetic process http://purl.obolibrary.org/obo/GO_0170033 L-amino acid metabolic process The chemical reactions and pathways resulting in the formation of L-amino acids, the L-enantiomers of amino acids. http://purl.obolibrary.org/obo/UBERON_0005876 undifferentiated genital tubercle http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure The embryonic anlage of the external genitalia, which emerges as paired swellings ventral to the cloacal membrane, is proposed to be derived from all three germ layers, and gives rise to the penis, clitoris, scrotum, labia, and foreskin. http://purl.obolibrary.org/obo/GO_0170035 L-amino acid catabolic process http://purl.obolibrary.org/obo/GO_0170033 L-amino acid metabolic process The chemical reactions and pathways resulting in the breakdown of an L-amino acid. http://purl.obolibrary.org/obo/UBERON_0005879 pharyngeal cleft http://purl.obolibrary.org/obo/UBERON_0006846 surface groove An external pocketing of pharyngeal ectoderm that contacts a region of endoderm (a pharyngeal pouch) and interdigitates in the anterior and posterior directions by the pharyngeal arches. http://purl.obolibrary.org/obo/GO_0170038 proteinogenic amino acid biosynthetic process http://purl.obolibrary.org/obo/GO_0170039 proteinogenic amino acid metabolic process The chemical reactions and pathways resulting in the formation of any amino acid that is incorporated into protein naturally by ribosomal translation of mRNA, and that has a specific codon for translation from mRNA to protein. http://purl.obolibrary.org/obo/UBERON_0005881 autopodial extension http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision A subdivision of the autopod that corresponds to one or more bones arranged in series branching from the main limb axis. http://purl.obolibrary.org/obo/GO_0170039 proteinogenic amino acid metabolic process http://purl.obolibrary.org/obo/GO_0006520 amino acid metabolic process The chemical reactions and pathways involving any amino acid that is incorporated into protein naturally by ribosomal translation of mRNA, and that has a specific codon for translation from mRNA to protein. http://purl.obolibrary.org/obo/UBERON_0005882 neural tube alar plate http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure The mantle layer of the neural tube that lies dorsal to the sulcus limitans and contains primarily sensory neurons and interneurons involved in communication of sensory impulses. http://purl.obolibrary.org/obo/UBERON_0005884 hyoid arch skeleton http://purl.obolibrary.org/obo/UBERON_0010912 subdivision of skeleton A subdivision of skeleton that supports pharyngeal arch 2. http://purl.obolibrary.org/obo/GO_0170040 proteinogenic amino acid catabolic process http://purl.obolibrary.org/obo/GO_0170039 proteinogenic amino acid metabolic process The chemical reactions and pathways resulting in the breakdown of any amino acid that is incorporated into protein naturally by ribosomal translation of mRNA, and that has a specific codon for translation from mRNA to protein. http://purl.obolibrary.org/obo/UBERON_0005891 coelomic epithelium http://purl.obolibrary.org/obo/UBERON_0000483 epithelium The epithelial lining of the surface of the coelom. http://purl.obolibrary.org/obo/GO_0170043 non-proteinogenic amino acid biosynthetic process http://purl.obolibrary.org/obo/GO_0170041 non-proteinogenic amino acid metabolic process The chemical reactions and pathways resulting in the formation of non-proteinogenic amino acids. http://purl.obolibrary.org/obo/UBERON_0005893 leg bone http://purl.obolibrary.org/obo/UBERON_0003464 hindlimb bone A bone that is part of the region of the hindlimb that includes the zeugopod and stylopod. Examples: patella, femur, tibia. Counter-examples: any pes phalanx. http://purl.obolibrary.org/obo/GO_0170044 non-proteinogenic amino acid catabolic process http://purl.obolibrary.org/obo/GO_0170041 non-proteinogenic amino acid metabolic process The chemical reactions and pathways resulting in the breakdown of non-proteinogenic amino acids. http://purl.obolibrary.org/obo/UBERON_0005897 manus bone http://purl.obolibrary.org/obo/UBERON_0011250 autopod bone A bone that is part of the manus skeleton. Note that this includes the carpal bones. http://purl.obolibrary.org/obo/GO_0160133 bicarbonate channel activity http://purl.obolibrary.org/obo/GO_0015267 channel activity Enables the energy-independent facilitated diffusion of bicarbonate through a transmembrane aqueous pore or channel. http://purl.obolibrary.org/obo/UBERON_0005899 pes bone http://purl.obolibrary.org/obo/UBERON_0011250 autopod bone A bone that is part of the pes skeleton. http://purl.obolibrary.org/obo/PATO_0010007 multiciliated http://purl.obolibrary.org/obo/PATO_0001408 ciliated A cellular quality inhering in a bearer by virtue of the bearer's having multiple cilia. http://purl.obolibrary.org/obo/UBERON_0005902 occipital region http://purl.obolibrary.org/obo/UBERON_0034921 multi organ part structure Anatomical cluster that is located in the posterior region of the cranium and forms the margin of the foramen magnum and occipital condyles. http://purl.obolibrary.org/obo/GO_0140001 morula formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The initial formation of a spherical embryonic mass of blastomeres formed before the blastula and resulting from cleavage of the fertilized ovum. http://purl.obolibrary.org/obo/UBERON_0005903 duct of seminal vesicle http://purl.obolibrary.org/obo/UBERON_0005904 duct of male reproductive system Each seminal vesicle consists of a single tube, coiled upon itself, and giving off several irregular cecal diverticula; the separate coils, as well as the diverticula, are connected together by fibrous tissue. When uncoiled, the tube is about the diameter of a quill, and varies in length from 10 to 15 cm.; it ends posteriorly in a cul-de-sac; its anterior extremity becomes constricted into a narrow straight duct called the excretory duct of seminal gland (or duct of the seminal vesicle), which joins with the corresponding ductus deferens to form the ejaculatory duct[WP]. http://purl.obolibrary.org/obo/GO_0151001 tuft http://purl.obolibrary.org/obo/GO_0098862 cluster of actin-based cell projections A dense cluster of elongated, thick microvilli on the apical surface of tuft cells in epithelial tissues, such as the intestine and respiratory tract. The apical tuft extends further into the lumen than typical microvilli, featuring larger, more compact projections with unique actin cores that penetrate deep into the cytoplasm, often reaching the perinuclear region. This distinctive structure, rich in microfilaments and microtubules, supports the chemosensory functions of the cell. http://purl.obolibrary.org/obo/UBERON_0005904 duct of male reproductive system http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure Any of the ducts that are part of a male reproductive system. http://purl.obolibrary.org/obo/UBERON_0005906 serous sac http://purl.obolibrary.org/obo/UBERON_0000062 organ Organ with organ cavity, which has as parts a serous membrane and a serous cavity . Examples: pleural sac, pericardial sac, tendon sheath, bursa.[FMA]. http://purl.obolibrary.org/obo/GO_0160231 cytospinule http://purl.obolibrary.org/obo/GO_0098858 actin-based cell projection An actin-based cell projection extending laterally from the basolateral membrane of tuft cells in epithelial tissues, including the intestinal epithelium. These thin projections, typically 3-4 per cell and up to 3 micron long, directly contact the nuclei of adjacent epithelial cells, potentially facilitating intercellular communication and molecular exchange. http://purl.obolibrary.org/obo/UBERON_0005908 conjunctival sac http://purl.obolibrary.org/obo/UBERON_0005906 serous sac A serous sac which is the aggregate of the conjunctiva plus the conjunctival space. http://purl.obolibrary.org/obo/CL_4300102 STR D2 Gaba indirect pathway medium spiny neuron (Mmus) http://purl.obolibrary.org/obo/CL_4023029 indirect pathway medium spiny neuron A indirect pathway medium spiny neuron of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Adora2a (Mmus), Phactr1 (Mmus), Pcp4l1 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Subclass:062 STR D2 Gaba. http://purl.obolibrary.org/obo/UBERON_0005911 endo-epithelium http://purl.obolibrary.org/obo/UBERON_0004119 endoderm-derived structure Epithelium that derives from the endoderm. Examples: urothelium, transitional epithelium of ureter, epithelium of prostatic gland.[FMA]. http://purl.obolibrary.org/obo/GO_1905951 mitochondrion DNA recombination http://purl.obolibrary.org/obo/GO_0006310 DNA recombination Any DNA recombination that takes place in mitochondrion. http://purl.obolibrary.org/obo/UBERON_0005928 external naris http://purl.obolibrary.org/obo/UBERON_0003102 surface structure A naris that provides one of the small external openings of the head that give passage to air for breathing. http://purl.obolibrary.org/obo/GO_1905955 negative regulation of endothelial tube morphogenesis http://purl.obolibrary.org/obo/GO_1901509 regulation of endothelial tube morphogenesis Any process that stops, prevents or reduces the frequency, rate or extent of endothelial tube morphogenesis. http://purl.obolibrary.org/obo/UBERON_0005932 bulb of hair follicle http://purl.obolibrary.org/obo/UBERON_0000479 tissue Thickening of the proximal end of the hair follicle. Contains rapidly proliferating, rather undifferentiated matrix cells (transient amplifying cells), melanocytes and outer root sheath cells. http://purl.obolibrary.org/obo/GO_1905956 positive regulation of endothelial tube morphogenesis http://purl.obolibrary.org/obo/GO_1901509 regulation of endothelial tube morphogenesis Any process that activates or increases the frequency, rate or extent of endothelial tube morphogenesis. http://purl.obolibrary.org/obo/UBERON_0005941 hair inner root sheath http://purl.obolibrary.org/obo/UBERON_0005933 hair root sheath A multilayered tube composed of terminally differentiated hair follicle keratinocytes that is surrounded by the outer root sheath; the layers of the inner root sheath include the companion layer, Henle's layer, Huxley's layer and the inner root sheath cuticle[MP]. http://purl.obolibrary.org/obo/GO_0090741 pigment granule membrane http://purl.obolibrary.org/obo/GO_0030659 cytoplasmic vesicle membrane Any membrane that is part of a pigment granule. http://purl.obolibrary.org/obo/UBERON_0005942 hair outer root sheath http://purl.obolibrary.org/obo/UBERON_0005933 hair root sheath A stratified epithelium that surrounds the hair follicle that merges proximally with the basal layer of the interfollicular epidermis and distally with the hair bulb. http://purl.obolibrary.org/obo/GO_0061880 regulation of anterograde axonal transport of mitochondrion http://purl.obolibrary.org/obo/GO_1902513 regulation of organelle transport along microtubule Any process that modulates the frequency, rate or extent of the directed movement of mitochondria along microtubules in axons away from the cell body and towards the presynapse. http://purl.obolibrary.org/obo/UBERON_0005944 axial skeleton plus cranial skeleton http://purl.obolibrary.org/obo/UBERON_0010912 subdivision of skeleton Subdivision of skeleton which consists of cranial skeleton, set of all vertebrae, set of all ribs and sternum[FMA, modified]. http://purl.obolibrary.org/obo/GO_0061881 positive regulation of anterograde axonal transport of mitochondrion http://purl.obolibrary.org/obo/GO_0061880 regulation of anterograde axonal transport of mitochondrion Any process that activates or increasesthe frequency, rate or extent of the directed movement of mitochondria along microtubules in axons away from the cell body and towards the presynapse. http://purl.obolibrary.org/obo/UBERON_0005946 outflow tract of atrium http://purl.obolibrary.org/obo/UBERON_0004145 outflow tract An outflow tract that is part of a cardiac atrium. http://purl.obolibrary.org/obo/GO_0061882 negative regulation of anterograde axonal transport of mitochondrion http://purl.obolibrary.org/obo/GO_0061880 regulation of anterograde axonal transport of mitochondrion Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of mitochondria along microtubules in axons away from the cell body and towards the presynapse. http://purl.obolibrary.org/obo/UBERON_0005953 outflow part of right ventricle http://purl.obolibrary.org/obo/UBERON_0005337 outflow tract of ventricle Anteriosuperior, smooth-walled portion of the cavity of the right ventricle, beginning at the supraventricular crest and terminating in the pulmonary trunk. http://purl.obolibrary.org/obo/GO_0061888 regulation of astrocyte activation http://purl.obolibrary.org/obo/GO_0050865 regulation of cell activation Any process that modulates the frequency, rate or extent of astrocyte activation. http://purl.obolibrary.org/obo/UBERON_0005956 outflow part of left ventricle http://purl.obolibrary.org/obo/UBERON_0005337 outflow tract of ventricle Anterosuperior fibrous portion of the left ventricle that connects to the ascending aorta. http://purl.obolibrary.org/obo/GO_0061889 negative regulation of astrocyte activation http://purl.obolibrary.org/obo/GO_0150079 negative regulation of neuroinflammatory response Any process that decreases the frequency, rate or extent of astrocyte activation. http://purl.obolibrary.org/obo/UBERON_0005965 outflow part of right atrium http://purl.obolibrary.org/obo/UBERON_0005946 outflow tract of atrium Outflow part of atrium which consists of wall and cavity of the outflow part of right atrium and the tricuspid valve.[FMA]. http://purl.obolibrary.org/obo/GO_0061890 positive regulation of astrocyte activation http://purl.obolibrary.org/obo/GO_0150078 positive regulation of neuroinflammatory response Any process that increases the frequency, rate or extent of astrocyte activation. http://purl.obolibrary.org/obo/UBERON_0005966 outflow part of left atrium http://purl.obolibrary.org/obo/UBERON_0005946 outflow tract of atrium An outflow tract of atrium that is part of a left atrium. http://purl.obolibrary.org/obo/GO_0150038 postsynaptic dense core vesicle exocytosis http://purl.obolibrary.org/obo/GO_0099003 vesicle-mediated transport in synapse The secretion of molecules (e.g. neuropeptides, insulin-related peptides or neuromodulators such as serotonin and dopamine) contained within a postsynaptic dense core vesicle by fusion of the granule with the plasma membrane of the postsynapse in response to increased cytosolic calcium levels. http://purl.obolibrary.org/obo/UBERON_0005969 eye trabecular meshwork http://purl.obolibrary.org/obo/UBERON_0000479 tissue A pore-like structure surrounding the entire circumference of the anterior chamber of the eye through which aqueous humor circulates[MP]. http://purl.obolibrary.org/obo/GO_0150195 transport across blood-cerebrospinal fluid barrier http://purl.obolibrary.org/obo/GO_0010232 vascular transport The directed movement of substances (e.g. macromolecules, small molecules, ions) through the blood-cerebrospinal fluid barrier. http://purl.obolibrary.org/obo/UBERON_0005970 brain commissure http://purl.obolibrary.org/obo/UBERON_0007702 tract of brain Any of the nerve fiber tracts that span the longitudinal fissure between the cerebral and/or cerebellar hemispheres of the brain. http://purl.obolibrary.org/obo/UBERON_0005971 amniotic fold http://purl.obolibrary.org/obo/UBERON_0000478 extraembryonic structure A sheet of somatopleure that grows upward over the embryo and eventually meets in the midline enclosing the embryo, eventually giving rise to the amnion and chorion[Kardong]. http://purl.obolibrary.org/obo/GO_0150200 regulation of transport across blood-brain barrier http://purl.obolibrary.org/obo/GO_0051049 regulation of transport Any process that modulates the frequency, rate or extent of transport across the blood-brain barrier. http://purl.obolibrary.org/obo/UBERON_0005978 olfactory bulb outer nerve layer http://purl.obolibrary.org/obo/UBERON_0004001 olfactory bulb layer Superficial layer of the main olfactory bulb containing axons from the olfactory nerve and glial cells. http://purl.obolibrary.org/obo/GO_0150201 positive regulation of transport across blood-brain barrier http://purl.obolibrary.org/obo/GO_0150200 regulation of transport across blood-brain barrier Any process that activates or increases the frequency, rate or extent of transport across blood-brain barrier. http://purl.obolibrary.org/obo/UBERON_0005979 crista terminalis http://purl.obolibrary.org/obo/UBERON_0000064 organ part The vertical crest of the interior wall of the right atrium that lies to the right of the sinus of the vena cava and separates this from the remainder of the right atrium. http://purl.obolibrary.org/obo/GO_0150202 negative regulation of transport across blood-brain barrier http://purl.obolibrary.org/obo/GO_0150200 regulation of transport across blood-brain barrier Any process that stops, prevents or reduces the frequency, rate or extent of transport across blood-brain barrier. http://purl.obolibrary.org/obo/UBERON_0005983 heart layer http://purl.obolibrary.org/obo/UBERON_0004923 organ component layer The laminar structure of the heart. http://purl.obolibrary.org/obo/PR_000050032 immunoglobulin complex (human) http://purl.obolibrary.org/obo/GO_0019814 immunoglobulin complex An immunoglobulin complex whose components are encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0005985 coronary vessel http://purl.obolibrary.org/obo/UBERON_0000055 vessel Any of the arteries or veins that supply blood to the heart or return blood from the heart muscles to the circulation. http://purl.obolibrary.org/obo/PR_000050370 H-2 class II histocompatibility antigen, E alpha chain (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein An MHC class II histocompatibility antigen alpha chain DRA that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0005986 left bundle branch http://purl.obolibrary.org/obo/UBERON_0018649 cardiac muscle tissue of ventricle The left branch of the atrioventricular bundle that separates at the bundle of His, descends the septal wall of the left ventricle and connects to the terminal Purkinje fiber[MP]. http://purl.obolibrary.org/obo/PR_000050467 hemoglobin subunit http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human HBA1, HBA2, HBB, HBD, HBE1, HBG1, HBG2, HBM, HBQ1, or HBZ genes, 1:1 orthologs thereof, or semi-orthologs thereof. http://purl.obolibrary.org/obo/UBERON_0005987 right bundle branch http://purl.obolibrary.org/obo/UBERON_0018649 cardiac muscle tissue of ventricle The right branch of the atrioventricular bundle that separates just below the bundle of His, descends the septal wall of the right ventricle and connects to the terminal Purkinje fibers[MP]. http://purl.obolibrary.org/obo/PATO_0070009 fan Martinotti morphology http://purl.obolibrary.org/obo/PATO_0070007 Martinotti morphology A Martinotti cell morphology that inheres in neurons which have axons that form a fan-like plexus. http://purl.obolibrary.org/obo/UBERON_0005988 atrium myocardial trabecula http://purl.obolibrary.org/obo/UBERON_0000440 trabecula The supporting bundles of muscular fibers lining the walls of the atrial myocardium. http://purl.obolibrary.org/obo/CL_4023090 small basket cell http://purl.obolibrary.org/obo/CL_2000086 neocortex basket cell A basket cell with axonal arbors composed of frequent, short, curvy axonal branches that tend to be near their somata and within the same layer. http://purl.obolibrary.org/obo/UBERON_0005989 atrioventricular septum http://purl.obolibrary.org/obo/UBERON_0010313 neural crest-derived structure The wall of the heart that separates the right atrium and left ventricle; and is located just above the septal cusp of the tricuspid valve. http://purl.obolibrary.org/obo/UBERON_0006002 vitelline artery http://purl.obolibrary.org/obo/UBERON_0004365 vitelline blood vessel The paired arteries that carry blood to the yolk sac from the dorsal aorta. http://purl.obolibrary.org/obo/CL_0008049 Betz cell http://purl.obolibrary.org/obo/CL_2000049 primary motor cortex pyramidal cell A giant pyramidal neuron with a soma in layer Vb of the primary motor cortex that sends its axons down the spinal cord via the corticospinal tract, either synapsing directly with alpha motor neurons, or targeting interneurons in the spinal cord. In humans, Betz cells are the largest known in the central nervous system. http://purl.obolibrary.org/obo/UBERON_0006003 integumentary adnexa http://purl.obolibrary.org/obo/UBERON_0000064 organ part Anatomical structure embedded in or located in the integument that is part of the integumental system. Examples: hair, follicles, skin glands, claws, nails, feathers. http://purl.obolibrary.org/obo/CL_0009029 mesothelial cell of appendix http://purl.obolibrary.org/obo/CL_0008041 mesothelial cell of intestine A mesothelial cell that is located in a vermiform appendix. http://purl.obolibrary.org/obo/UBERON_0006004 hair follicle matrix region http://purl.obolibrary.org/obo/UBERON_0019204 skin epithelium The bulb region adjacent to the dermal papilla that contains rapidly proliferating matrix cells that give rise to the various cell lineages of the hair shaft and inner root sheath. http://purl.obolibrary.org/obo/CL_4023071 L5/6 cck GABAergic interneuron (Mmus) http://purl.obolibrary.org/obo/CL_0010011 cerebral cortex GABAergic interneuron A GABAergic cortical interneuron that expresses cck. L5/6 cck cells have soma found mainly in L5 and L6 and have large axonal arborization. http://purl.obolibrary.org/obo/UBERON_0006005 hair follicle isthmus http://purl.obolibrary.org/obo/UBERON_0019204 skin epithelium The middle part of the hair follicle that extends from the sebaceous duct to the bulge. http://purl.obolibrary.org/obo/CL_4023080 stellate L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (Mmus) http://purl.obolibrary.org/obo/CL_4023093 stellate pyramidal neuron a L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex that has stellate pyramidal morphology. http://purl.obolibrary.org/obo/UBERON_0006008 fibrous ring of heart http://purl.obolibrary.org/obo/UBERON_0006444 annulus fibrosus A ring of ribrous tissue that surrounds the atrioventricular and arterial orifices. http://purl.obolibrary.org/obo/CL_4023047 L2/3 intratelencephalic projecting glutamatergic neuron of the primary motor cortex http://purl.obolibrary.org/obo/CL_4030059 L2/3 intratelencephalic projecting glutamatergic neuron An intratelencephalic-projecting glutamatergic neuron with a soma found in cortical layer 2/3 of the primary motor cortex. http://purl.obolibrary.org/obo/UBERON_0006058 multi-limb segment region http://purl.obolibrary.org/obo/UBERON_0010758 subdivision of organism along appendicular axis A collection of two or more connected limb segments. Examples: arm (comprising stylopod and zeugopod regions). http://purl.obolibrary.org/obo/CL_0009034 dendritic cell of appendix http://purl.obolibrary.org/obo/CL_0000451 dendritic cell A dendritic cell that is located in a vermiform appendix. http://purl.obolibrary.org/obo/UBERON_0006061 process of vertebra http://purl.obolibrary.org/obo/UBERON_4100000 skeletal element projection A process projection from a part of the vertebra such as centrum or arches. Examples: transverse process, diapophyses, parapophyses, and zygapophyses (both the cranial zygapophyses and the caudal zygapophyses). http://purl.obolibrary.org/obo/CL_4023076 Martinotti neuron http://purl.obolibrary.org/obo/CL_0011005 GABAergic interneuron An interneuron that has Martinotti morphology. These interneurons are scattered throughout various layers of the cerebral cortex, sending their axons up to the cortical layer I where they form axonal arborization. http://purl.obolibrary.org/obo/UBERON_0006063 cartilaginous neural arch http://purl.obolibrary.org/obo/UBERON_0010358 arch of centrum of vertebra One of the cartilaginous structures surrounding the embryonic spinal cord, formed by the dorsal growth of the dorsolateral arcualia; it is the primordium of the vertebral arch. http://purl.obolibrary.org/obo/UBERON_0006067 musculature of hindlimb zeugopod http://purl.obolibrary.org/obo/UBERON_0004466 musculature of leg Any collection of muscles that is part of a hindlimb zeugopod. http://purl.obolibrary.org/obo/CL_0009055 paneth cell of anorectum http://purl.obolibrary.org/obo/CL_0002658 glandular cell of the large intestine A paneth cell that is located in the anorectum. http://purl.obolibrary.org/obo/UBERON_0006068 bone of tail http://purl.obolibrary.org/obo/UBERON_0001474 bone element A bone that is part of a post-anal tail. http://purl.obolibrary.org/obo/CL_0009057 anorectum goblet cell http://purl.obolibrary.org/obo/CL_1000320 large intestine goblet cell A goblet cell that is located in the anorectum. http://purl.obolibrary.org/obo/UBERON_0006071 caudal region http://purl.obolibrary.org/obo/UBERON_0011676 subdivision of organism along main body axis Subdivision of an organism along anterior-posterior axis that is the posteriormost region, extending past the anus (or cloaca, if present), consisting of a tail in some fully formed chordates (or a tail bud in embryos). In animals that have a sacral region, this is the region immediately posterior to this. http://purl.obolibrary.org/obo/UBERON_0006072 cervical region of vertebral column http://purl.obolibrary.org/obo/UBERON_0006077 subdivision of vertebral column That portion of the spine comprising the cervical vertebrae. The neck area of the spine. http://purl.obolibrary.org/obo/CL_0009058 enterocyte of anorectum http://purl.obolibrary.org/obo/CL_0002071 enterocyte of epithelium of large intestine An enterocyte that is located in the anorectum. http://purl.obolibrary.org/obo/UBERON_0006073 thoracic region of vertebral column http://purl.obolibrary.org/obo/UBERON_0006077 subdivision of vertebral column That part of the spine comprising the thoracic vertebrae. http://purl.obolibrary.org/obo/CL_0009063 enteroendocrine cell of anorectum http://purl.obolibrary.org/obo/CL_1001516 intestinal enteroendocrine cell An enteroendocrine cell that is located in the anorectum. http://purl.obolibrary.org/obo/UBERON_0006074 lumbar region of vertebral column http://purl.obolibrary.org/obo/UBERON_0006077 subdivision of vertebral column Subdivision of vertebral column that corresponds to the lumbar subdivision of the body, containing the lumbar vertebrae. http://purl.obolibrary.org/obo/UBERON_8440004 laminar subdivision of the cortex http://purl.obolibrary.org/obo/UBERON_0011215 central nervous system cell part cluster One or a subset of adjacent layers of the neocortex. http://purl.obolibrary.org/obo/UBERON_0006075 sacral region of vertebral column http://purl.obolibrary.org/obo/UBERON_0006077 subdivision of vertebral column Subdivision of vertebral column that corresponds to the sacral subdivision of the body, containing the sacral vertebrae or sacrum. http://purl.obolibrary.org/obo/CL_4028001 pulmonary capillary endothelial cell http://purl.obolibrary.org/obo/CL_2000016 lung microvascular endothelial cell Any capillary endothelial cell that is part of a lung. http://purl.obolibrary.org/obo/UBERON_0006076 caudal region of vertebral column http://purl.obolibrary.org/obo/UBERON_0006077 subdivision of vertebral column Subdivision of vertebral column that corresponds to the caudal subdivision of the body, containing the caudal vertebrae. http://purl.obolibrary.org/obo/UBERON_0006077 subdivision of vertebral column http://purl.obolibrary.org/obo/UBERON_0000075 subdivision of skeletal system A collection of all skeletal elements in some subdivision of the vertebral column. http://purl.obolibrary.org/obo/CL_0009085 colony forming unit – Hill cell http://purl.obolibrary.org/obo/CL_0002619 adult endothelial progenitor cell An adult endothelial progenitor cell characterised in vivo by homing to ischemic sites and paracrine support of angiogenesis. They may form discrete colonies. http://purl.obolibrary.org/obo/UBERON_0006082 fundus of urinary bladder http://purl.obolibrary.org/obo/UBERON_0000064 organ part The base or posterior surface of the urinary bladder contains the trigone of the bladder and the outlet where urine empties through the internal urethral orifice. http://purl.obolibrary.org/obo/CL_0009106 medullary reticular cell http://purl.obolibrary.org/obo/CL_0009102 lymph node fibroblastic reticular cell A specialized fibroblast found in the medulla of lymph node. http://purl.obolibrary.org/obo/UBERON_0006098 basal nuclear complex http://purl.obolibrary.org/obo/UBERON_0019264 gray matter of forebrain The deep nuclei of telencephalic origin found in the basal region of the forebrain. http://purl.obolibrary.org/obo/CL_4030026 BEST4+ enterocyte http://purl.obolibrary.org/obo/CL_0000584 enterocyte An enterocyte of the human intestine expressing bestrophin-4 (BEST4) calcium-activated ion channels. http://purl.obolibrary.org/obo/UBERON_0006107 basolateral amygdaloid nuclear complex http://purl.obolibrary.org/obo/UBERON_0007245 nuclear complex of neuraxis A set of amygdalar nuclei comprising the lateral nucleus (LA), the basal nucleus (BA), and the accessory basal nuclei (ABN). These nuclei are bordered laterally by the external capsule and medially by the central amygdalar nucleus as well as the amygdalohippocampal area. This definition refers to the rat Basolateral nuclear complex. http://purl.obolibrary.org/obo/CL_0003043 M10 retinal ganglion cell http://purl.obolibrary.org/obo/CL_0000740 retinal ganglion cell A monostratified retinal ganglion cell with large soma and large dendritic field, with dense dendritic arbor. http://purl.obolibrary.org/obo/UBERON_0006108 corticomedial nuclear complex http://purl.obolibrary.org/obo/UBERON_0007245 nuclear complex of neuraxis These structures are referred to as nuclei but have a layered cortical like structure. These areas include the anterior amygdaloid area, posterior amygdaloid area, the periamygdaloid cortex, and the bed nucleus of the accessory olfactory tract. http://purl.obolibrary.org/obo/CL_0003032 M3-OFF retinal ganglion cell http://purl.obolibrary.org/obo/CL_4023033 OFF retinal ganglion cell A monostratified retinal ganglion cell that has post synaptic terminals in sublaminar layer S2 and is depolarized by decreased illumination of their receptive field center http://purl.obolibrary.org/obo/UBERON_0006127 funiculus of spinal cord http://purl.obolibrary.org/obo/UBERON_0006133 funiculus of neuraxis A funiculus of neuraxis that is part of a spinal cord. http://purl.obolibrary.org/obo/CL_0004126 retinal ganglion cell C2 outer http://purl.obolibrary.org/obo/CL_0003020 retinal ganglion cell C outer A retinal ganglion cell C outer that has symmetrical and dense dendritic dendritic tree with a large dendritic field. http://purl.obolibrary.org/obo/UBERON_0006133 funiculus of neuraxis http://purl.obolibrary.org/obo/UBERON_0011215 central nervous system cell part cluster The cerebrospinal nerves consist of numerous nerve fibers collected together and enclosed in membranous sheaths. A small bundle of fibers, enclosed in a tubular sheath, is called a funiculus; if the nerve is of small size, it may consist only of a single funiculus; but if large, the funiculi are collected together into larger bundles or fasciculi, which are bound together in a common membranous investment. Examples include: Anterior funiculus of the spinal cord Lateral funiculus of the spinal cord Posterior funiculus of the spinal cord Funiculus solitarius of the medulla Funiculus separans. http://purl.obolibrary.org/obo/CL_4023072 brain vascular cell http://purl.obolibrary.org/obo/CL_0002319 neural cell A cell that is part of the brain vasculature. http://purl.obolibrary.org/obo/UBERON_0006134 nerve fiber http://purl.obolibrary.org/obo/UBERON_0005162 multi cell part structure A threadlike extension of a nerve cell and consists of an axon and myelin sheath (if it is myelinated) in the nervous system. There are nerve fibers in the central nervous system and peripheral nervous system. A nerve fiber may be myelinated and/or unmyelinated. In the central nervous system (CNS), myelin by oligodendroglia cells is formed. Schwann cells form myelin in the peripheral nervous system (PNS). Schwann cells also make a thin covering in an axon without myelin (in the PNS). A peripheral nerve fiber contains an axon, myelin sheath, schwann cells and its endoneurium. There are no endoneurium and schwann cells in the central nervous system. http://purl.obolibrary.org/obo/UBERON_8600018 neuroendocrine system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system A regulatory system of the body that integrates the nervous system and the endocrine system. This system is formed by specialized neuroendocrine cells located mainly in the nervous system and neuroendocrine glands. However, they can also be found as either single cells or small clusters of cells dispersed throughout the surface epithelium of different tissues. The neuroendocrine system functions through the release of neurotransmitters and neurohormones, enabling communication between the endocrine and nervous systems to govern vitally important processes that include growth, reproduction, metabolism and energy homeostasis, electrolyte and water balance, and responses to stress. http://purl.obolibrary.org/obo/UBERON_0006135 myelinated nerve fiber http://purl.obolibrary.org/obo/UBERON_0006134 nerve fiber Axons of neurons encased in a lipoproteinaceous material called myelin. (MeSH). http://purl.obolibrary.org/obo/CL_4040006 dermal chromatophore http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell A chromatophore that is part of the dermis. http://purl.obolibrary.org/obo/UBERON_0006170 mesonephric capsule http://purl.obolibrary.org/obo/UBERON_0002015 kidney capsule The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue. http://purl.obolibrary.org/obo/CL_4042001 TAC3-positive striatal interneuron http://purl.obolibrary.org/obo/CL_0011005 GABAergic interneuron A GABAergic interneuron that has its soma located in the striatum and that has an enriched expression of the genes TAC3 and LHX6. http://purl.obolibrary.org/obo/UBERON_0006182 mesonephric glomerular mesangium http://purl.obolibrary.org/obo/UBERON_0002320 glomerular mesangium The mesonephric glomerular mesangium is the thin membrane connective tissue composed of mesangial cells in the mesonephros, which helps to support the capillary loops in a renal glomerulus. http://purl.obolibrary.org/obo/CL_4042002 TAC3-positive medium spiny neuron http://purl.obolibrary.org/obo/CL_4030051 nucleus accumbens shell and olfactory tubercle D1 medium spiny neuron A nucleus accumbens shell and olfactory tubercle D1 medium spiny neuron that co-expresses TAC3 and the DRD1 receptor. http://purl.obolibrary.org/obo/UBERON_0006183 mesonephric glomerular capillary http://purl.obolibrary.org/obo/UBERON_0004212 glomerular capillary Missing definition for term UBERON:0006183. Please replace it using linked reference. http://purl.obolibrary.org/obo/CL_4042003 border associated macrophage http://purl.obolibrary.org/obo/CL_0000878 central nervous system macrophage A central nervous system macrophage that is part of a choroid plexus, a meninx and a perivascular space. A border associated macrophage interacts with various components of the CNS vasculature and meninges, it participates in immune surveillance and in the regulation of the blood brain barrier. http://purl.obolibrary.org/obo/UBERON_0006189 mesonephric connecting tubule http://purl.obolibrary.org/obo/UBERON_0005330 mesonephric nephron epithelium The mesonephric connecting tubule is a tubular segment of the mesonephric nephron; it connects the distal tubule to the collecting duct in the mesonephros. http://purl.obolibrary.org/obo/CL_4042004 choroid epiplexus macrophage http://purl.obolibrary.org/obo/CL_0000880 choroid plexus macrophage A choroid plexus macrophage that is part of the apical surface of some choroid plexus epithelium. This macrophage has a star-like shaped body. http://purl.obolibrary.org/obo/UBERON_0006190 mesonephric distal tubule http://purl.obolibrary.org/obo/UBERON_0005330 mesonephric nephron epithelium The mesonephric distal tubule is a mesonephric nephron tubule that begins at the macula densa and extends to the mesonephric connecting tubule. http://purl.obolibrary.org/obo/CL_4042005 stromal choroid plexus macrophage http://purl.obolibrary.org/obo/CL_0000880 choroid plexus macrophage A choroid plexus macrophage that is part of a choroid plexus stroma. http://purl.obolibrary.org/obo/UBERON_0006192 mesonephric proximal tubule http://purl.obolibrary.org/obo/UBERON_0005330 mesonephric nephron epithelium The mesonephric proximal tubule extends from the capsule to the distal tubule. http://purl.obolibrary.org/obo/CL_4042006 dural macrophage http://purl.obolibrary.org/obo/CL_4042003 border associated macrophage A border associated macrophage which is part of a dura matter. This macrophage phagocytoses intruding pathogens and foreign molecules detected in the bloodstream or in the cerebrospinal fluid. This cell has an amoeboid body with dynamic protrusions in homeostasis. http://purl.obolibrary.org/obo/UBERON_0006206 iridocorneal angle http://purl.obolibrary.org/obo/UBERON_0000015 non-material anatomical boundary Acute angle occurring between the iris and the cornea at the periphery of the anterior chamber of the eye[MP]. http://purl.obolibrary.org/obo/CL_0008041 mesothelial cell of intestine http://purl.obolibrary.org/obo/CL_0000077 mesothelial cell A mesothelial cell that is part of the intestinal serosa. http://purl.obolibrary.org/obo/UBERON_0006207 aortico-pulmonary spiral septum http://purl.obolibrary.org/obo/UBERON_0004142 outflow tract septum The spiral septum that separates the truncus arteriosus into a ventral pulmonary trunk and the dorsal aorta[MP]. The aorticopulmonary septum is developmentally formed from neural crest, specifically the cardiac neural crest, and actively separates the aorta and pulmonary arteries and fuses with the interventricular septum within the heart during development. The actual mechanism of septation of the outflow tract is poorly understood, but is recognized as a dynamic process with contributions from contractile, hemodynamic, and extracellular matrix interactions. http://purl.obolibrary.org/obo/CL_4033094 age-associated B cell http://purl.obolibrary.org/obo/CL_0000787 memory B cell A transcriptionally distinct memory B cell whose presence increases with age, during infections, and in autoimmune diseases. In humans and mice, this cell type can be identified by the expression of T-bet, CD11c, CD11b, and the lack of CD21. An age-associated B cell responds to TLR stimuli, may produce autoantibodies, and participates in antiviral responses and pathogen clearance. http://purl.obolibrary.org/obo/UBERON_0006208 auditory hillocks http://purl.obolibrary.org/obo/UBERON_0000477 anatomical cluster A collection of protruberances derived from pharyngeal arches 1 and 2 that develop into the folds of the pinna and gradually shift upwards and backwards to their final position on the head. http://purl.obolibrary.org/obo/CL_4033095 diffuse bipolar 4a cell http://purl.obolibrary.org/obo/CL_0000749 ON-bipolar cell An ON bipolar cell that has high expression of DIRC3, KCNJ3, LINC01915, PTPRK compared with other bipolar cells. http://purl.obolibrary.org/obo/UBERON_0006211 buccopharyngeal membrane http://purl.obolibrary.org/obo/UBERON_0003037 septum The thin bilaminar membrane derived from the prechordal plate that is devoid of mesoderm and formed by the apposition of the stomodeal ectoderm with the foregut endoderm; after the embryonic head fold has evolved it lies at the caudal limit of the stomodeum, forming a septum between the primitive mouth and pharynx; the membrane eventually disappears, and thus a communication is established between the mouth and the future pharynx. http://purl.obolibrary.org/obo/CL_4033096 diffuse bipolar 4b cell http://purl.obolibrary.org/obo/CL_0000749 ON-bipolar cell An ON bipolar cell that has high expression of NOS1AP compared with other bipolar cells. http://purl.obolibrary.org/obo/UBERON_0006213 carpus cartilage element http://purl.obolibrary.org/obo/UBERON_0015049 carpus endochondral element A cartilaginous condensation that has the potential to develop into a carpal bone. http://purl.obolibrary.org/obo/CL_4047037 stomach smooth muscle inner oblique layer cell http://purl.obolibrary.org/obo/CL_4047034 smooth muscle cell of stomach A smooth muscle cell found in the innermost layer of the muscularis externa of the stomach wall. This cell forms a unique layer of smooth muscle fibers oriented obliquely to the stomach's longitudinal axis. It is responsible for aiding in the mixing and churning of gastric contents, contributing to mechanical digestion within the stomach. http://purl.obolibrary.org/obo/UBERON_0006214 carpus pre-cartilage condensation http://purl.obolibrary.org/obo/UBERON_0015049 carpus endochondral element A pre-cartilage condensation that has the potential to develop into a carpal bone. http://purl.obolibrary.org/obo/CL_4047040 smooth muscle circular layer cell http://purl.obolibrary.org/obo/CL_0000192 smooth muscle cell A smooth muscle cell that is found in the inner muscular layer of hollow organs. It is characterized by its spiral/helical arrangement around organ lumens. This cell is crucial for peristaltic movements in organs. http://purl.obolibrary.org/obo/UBERON_0006215 rhombic lip http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure The posterior section of the developing metencephalon recognized transiently within the vertebrate embryo; the rhombic lip extends posteriorly from the roof of the fourth ventricle to dorsal neuroepithelial cell and can be divided into eight structural units based on rhombomeres 1-8 (r1-r8), recognized at early stages of hindbrain development; producing granule cells and five brainstem nuclei, the rhombic lip plays an important role in developing a complex cerebellar neural system. http://purl.obolibrary.org/obo/CL_4047043 type 1 submucosal plexus glia http://purl.obolibrary.org/obo/CL_4040002 enteroglial cell An enteric glial cell that is associated with neuron cell bodies within submucosal ganglia of the gastrointestinal tract. This cell is located in the submucosa, a layer of connective tissue beneath the intestinal mucosa. This cell plays a role in modulating secretomotor neuron activity and contributes to the regulation of digestive fluid secretion and absorption. http://purl.obolibrary.org/obo/UBERON_0006217 cloacal membrane http://purl.obolibrary.org/obo/UBERON_0000158 membranous layer The membrane that covers the embryonic cloaca, formed by the union of proctodeal (anal pit) ectoderm and cloacal endoderm, with no intervening mesoderm; the urorectal septum joins the cloacal membrane and divides it into an anal membrane and a urogenital membrane; the point where the urorectal septum intersects the cloacal membrane is the future site of the perineal body; proliferation of mesoderm and ectoderm around the cloacal membrane produces primordial tissues of the external genitalia in both sexes: the genital tubercle, genital folds, and genital swellings. http://purl.obolibrary.org/obo/UBERON_0006222 future diencephalon http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure The foremost region of the future forebrain that develops into the diencephalon. http://purl.obolibrary.org/obo/CL_4052032 granzyme H-associated CD8 T cell http://purl.obolibrary.org/obo/CL_0000909 CD8-positive, alpha-beta memory T cell A CD8 T cell characterized by high expression of Granzyme H (GZMH). This cell exhibits a restricted TCR repertoire and elevated expression of cytotoxic, exhaustion, and type I interferon-stimulated gene signatures compared to controls. http://purl.obolibrary.org/obo/UBERON_0006233 female genital tubercle http://purl.obolibrary.org/obo/UBERON_0011757 differentiated genital tubercle A differentiated genital tubercle that is part of a female reproductive system. http://purl.obolibrary.org/obo/UBERON_0006234 femur pre-cartilage condensation http://purl.obolibrary.org/obo/UBERON_0015052 femur endochondral element A femur endochondral element that is composed primarily of a pre-cartilage condensation. http://purl.obolibrary.org/obo/CL_4052033 biliary tuft cell http://purl.obolibrary.org/obo/CL_0002204 tuft cell A tuft cell that is part of the extrahepatic biliary tree, including the gallbladder and extrahepatic bile ducts. It shares a core genetic program with intestinal tuft cells but has unique tissue-specific genes. Biliary tuft cell functions as a bile acid-sensitive regulator, suppressing inflammation and modulating microbiome-dependent neutrophil infiltration in biliary tissues. Unlike its intestinal counterparts, this cell decreases in number postnatally as bile acid production matures, with its abundance negatively regulated by bile acids. http://purl.obolibrary.org/obo/UBERON_0006235 foregut-midgut junction http://purl.obolibrary.org/obo/UBERON_1100000 digestive tract junction An anatomical junctions that overlaps the foregut and midgut. http://purl.obolibrary.org/obo/CL_4052034 tuft cell of thymus http://purl.obolibrary.org/obo/CL_0002365 medullary thymic epithelial cell A tuft cell that is part of the medullary epithelium of the thymus, characterized by lateral microvilli and specific markers, including L1CAM in both mice (Zhang et al., 2022) and humans (Sun et al., 2023), as well as MHC II in mice (Miller et al., 2018). This cell is pivotal in immune functions such as antigen presentation, central tolerance, and type 2 immunity. A tuft cell in the thymus exhibits characteristics of both a medullary thymic epithelial cell (mTEC) and a peripheral tuft cell. Its development is governed by transcription factors such as POU2F3. http://purl.obolibrary.org/obo/UBERON_0006238 future brain http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure The embryonic precursor of the brain. http://purl.obolibrary.org/obo/CL_4052035 tuft cell of pancreatic duct http://purl.obolibrary.org/obo/CL_1001433 epithelial cell of exocrine pancreas A tuft cell that is part of the epithelium of pancreatic duct. Present in humans and rats, this cell is absent in the murine pancreas under normal conditions but emerges during acinar-to-ductal metaplasia triggered by injury, inflammation, or oncogenic mutations. It modulates the immune response and protects against pancreatic ductal adenocarcinoma progression by producing suppressive eicosanoids, such as prostaglandin D2. A tuft cell in the pancreatic duct highly expresses the transcription factor POU2F3, which is essential for its development and presence. http://purl.obolibrary.org/obo/UBERON_0006239 future central tendon http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure A tendon that has the potential to develop into a central tendon. http://purl.obolibrary.org/obo/CL_4052036 tuft cell of nasal cavity http://purl.obolibrary.org/obo/CL_0002631 epithelial cell of upper respiratory tract A tuft cell that is part of the nasal cavity epithelium, located in both the respiratory and olfactory epithelia of the nose. This cell plays key roles in chemosensation, lipid mediator production, immune responses, and epithelial homeostasis. http://purl.obolibrary.org/obo/UBERON_0006240 future forebrain http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure A presumptive structure that has the potential to develop into a forebrain. http://purl.obolibrary.org/obo/CL_4052037 tuft cell of olfactory epithelium http://purl.obolibrary.org/obo/CL_4052036 tuft cell of nasal cavity A tuft cell that is part of the olfactory epithelium, characterized by a globular body and the expression of neurogranin (Nrgn) in mice. This cell plays a crucial role in allergen recognition and regulating olfactory stem cell proliferation via TRPM5-dependent ATP sensing and cysteinyl leukotriene production. Unlike nasal respiratory tuft cells, it has low to absent expression of taste receptors, including the G protein Gα gustducin, and rarely contacts olfactory sensory neurons directly. http://purl.obolibrary.org/obo/UBERON_0006242 gallbladder primordium http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure A sac-like cavity ventral to the liver, lying in the sub-mesodermal space and closed by a thin sheet of ectodermal cells, from which the future gall bladder develops. http://purl.obolibrary.org/obo/CL_4052038 tuft cell of nasal cavity respiratory epithelium http://purl.obolibrary.org/obo/CL_4052036 tuft cell of nasal cavity A tuft cell that is part of the nasal cavity respiratory epithelium. Acting as a chemosensor, it detects bitter taste ligands and bacterial signals via taste receptors, maintaining epithelial-microbial homeostasis by stimulating antimicrobial peptide secretion from adjacent epithelial cells. This cell is a major source of IL-25, promoting type 2 immune responses and potentially contributing to chronic rhinosinusitis (O'Leary et al., 2019). http://purl.obolibrary.org/obo/UBERON_0006245 humerus cartilage element http://purl.obolibrary.org/obo/UBERON_0015053 humerus endochondral element A humerus endochondral element that is composed primarily of cartilage tissue. http://purl.obolibrary.org/obo/UBERON_0035036 naris epithelium http://purl.obolibrary.org/obo/UBERON_0000483 epithelium An epithelium that is part of a naris [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0006246 humerus pre-cartilage condensation http://purl.obolibrary.org/obo/UBERON_0015053 humerus endochondral element A humerus endochondral element that is composed primarily of a pre-cartilage condensation. http://purl.obolibrary.org/obo/UBERON_0035118 material entity in digestive tract http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure Any material entity that is located in the digestive tract. This includes undigested food and liquid as well as unexcreted waste products. It also includes other entities such as ingested stones used to aid digestion. Any microbial cells or cell populations are also included. http://purl.obolibrary.org/obo/UBERON_0006250 infundibular recess of 3rd ventricle http://purl.obolibrary.org/obo/UBERON_0007499 epithelial sac A funnel-shaped diverticulum that extends downward from the anterior aspect of the floor of the third ventricle into the infundibulum of the hypophysis; the embryonic structure gives rise the neural component of the pituitary (pas nervosa). http://purl.obolibrary.org/obo/UBERON_0035814 pericardial fat http://purl.obolibrary.org/obo/UBERON_0035818 visceral fat The sum of epicardial and paracardial fat deposits. http://purl.obolibrary.org/obo/UBERON_0006254 ischial cartilage element http://purl.obolibrary.org/obo/UBERON_0015056 ischial endochondral element An ischial endochondral element that is composed primarily of cartilage tissue. http://purl.obolibrary.org/obo/UBERON_0035818 visceral fat http://purl.obolibrary.org/obo/UBERON_0001013 adipose tissue Any fat deposit surrounding a visceral organ. http://purl.obolibrary.org/obo/UBERON_0006255 ischial pre-cartilage condensation http://purl.obolibrary.org/obo/UBERON_0015056 ischial endochondral element An ischial endochondral element that is composed primarily of a pre-cartilage condensation. http://purl.obolibrary.org/obo/UBERON_0036146 cardiopharyngeal field http://purl.obolibrary.org/obo/UBERON_0007688 anlage An region of the mesoderm that includes anterior lateral mesoderm of the first heart field plus contiguous pharyngeal mesoderm that gives rise to second-heart-field-derived regions of the heart and branchiomeric muscles. http://purl.obolibrary.org/obo/UBERON_0006261 male genital tubercle http://purl.obolibrary.org/obo/UBERON_0011757 differentiated genital tubercle A differentiated genital tubercle that is part of a male reproductive system. http://purl.obolibrary.org/obo/UBERON_0036150 skin appendage follicle http://purl.obolibrary.org/obo/UBERON_0000063 organ subunit An organ subunit in the skin that gives rise to cutaneous appendage. http://purl.obolibrary.org/obo/UBERON_0006264 mouth-foregut junction http://purl.obolibrary.org/obo/UBERON_0007651 anatomical junction An anatomical junctions that overlaps the mouth and foregut. http://purl.obolibrary.org/obo/UBERON_0034947 gas in respiratory system http://purl.obolibrary.org/obo/UBERON_0034873 bodily gas Any portion of gas located in a part of the respiratory system. http://purl.obolibrary.org/obo/UBERON_0006266 nasolacrimal groove http://purl.obolibrary.org/obo/UBERON_0019306 nose epithelium Groove between maxillary prominence and lateral nasal process. http://purl.obolibrary.org/obo/UBERON_0035159 entire surface of organism http://purl.obolibrary.org/obo/UBERON_0006984 anatomical surface Anatomical surface, which is the external surface of the whole body. Examples: There is only one body surface. http://purl.obolibrary.org/obo/UBERON_0006267 notochordal plate http://purl.obolibrary.org/obo/UBERON_0010371 ecto-epithelium The notochordal plate is the dorsal part of the notochordal process when the ventral portion breaks down. It is continuous laterally with the endoderm that composes the roof of the primitive foregut and is in contact dorsally with the neural tube. The folding off of the notochordal plate gives rise to the notochord. http://purl.obolibrary.org/obo/UBERON_0035174 right ear http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure The organ of hearing located on the right side of the head. http://purl.obolibrary.org/obo/UBERON_0035295 left ear http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure The organ of hearing located on the left side of the head[ncit,modified]. http://purl.obolibrary.org/obo/UBERON_0006268 notochordal process http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure A midline cellular cord formed from the migration of mesenchymal cells from the primitive knot. http://purl.obolibrary.org/obo/GO_0110011 regulation of basement membrane organization http://purl.obolibrary.org/obo/GO_1903053 regulation of extracellular matrix organization Any process that modulates the frequency, rate or extent of the assembly, disassembly or arrangement of constituent parts of the basement membrane. http://purl.obolibrary.org/obo/UBERON_0006271 orbital fissure http://purl.obolibrary.org/obo/UBERON_0013685 foramen of skull Either of two openings transmitting nerves and blood vessels to or from the orbit. http://purl.obolibrary.org/obo/GO_0140021 mitochondrial ADP transmembrane transport http://purl.obolibrary.org/obo/GO_1901679 nucleotide transmembrane transport The process in which ADP is transported across a mitochondrial membrane, into or out of the mitochondrion. http://purl.obolibrary.org/obo/UBERON_0006273 otic pit http://purl.obolibrary.org/obo/UBERON_0016566 pit The pair of depressions of thickened otic placode epithelium, that further develops into the otic vesicles. http://purl.obolibrary.org/obo/GO_0120031 plasma membrane bounded cell projection assembly http://purl.obolibrary.org/obo/GO_0030031 cell projection assembly Formation of a prolongation or process extending and that is bounded by plasma membrane, e.g. a cilium, lamellipodium, or axon. http://purl.obolibrary.org/obo/UBERON_0006279 pleuroperitoneal canal http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue Each of the canals that links the peritoneal cavity and the caudal part of a pleural cavity. http://purl.obolibrary.org/obo/GO_0120035 regulation of plasma membrane bounded cell projection organization http://purl.obolibrary.org/obo/GO_0031344 regulation of cell projection organization Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of plasma membrane bounded cell projections. http://purl.obolibrary.org/obo/UBERON_0006283 future cardiac ventricle http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure Multi-tissue structure that is part of the heart tube and will become the cardiac ventricle. http://purl.obolibrary.org/obo/GO_0106014 regulation of inflammatory response to wounding http://purl.obolibrary.org/obo/GO_0050727 regulation of inflammatory response Any process that modulates the frequency, rate or extent of the inflammatory response to wounding. http://purl.obolibrary.org/obo/GO_0106015 negative regulation of inflammatory response to wounding http://purl.obolibrary.org/obo/GO_0106014 regulation of inflammatory response to wounding Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response to wounding. http://purl.obolibrary.org/obo/GO_0106016 positive regulation of inflammatory response to wounding http://purl.obolibrary.org/obo/GO_0106014 regulation of inflammatory response to wounding Any process that activates or increases the frequency, rate or extent of the inflammatory response to wounding. http://purl.obolibrary.org/obo/UBERON_0006284 early prosencephalic vesicle http://purl.obolibrary.org/obo/UBERON_0013150 future brain vesicle Future brain vesicle that gives rise to telencephalic ventricle/lateral ventricles and 3rd ventricle. http://purl.obolibrary.org/obo/GO_0104004 cellular response to environmental stimulus http://purl.obolibrary.org/obo/GO_0051716 cellular response to stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an environmental stimulus. http://purl.obolibrary.org/obo/UBERON_0006288 rib cartilage element http://purl.obolibrary.org/obo/UBERON_0015019 rib endochondral element A rib endochondral element that is composed primarily of cartilage tissue. http://purl.obolibrary.org/obo/GO_0099182 presynaptic intermediate filament cytoskeleton http://purl.obolibrary.org/obo/GO_0099569 presynaptic cytoskeleton The intermediate filament cytoskeleton that is part of a presynapse. http://purl.obolibrary.org/obo/UBERON_0006289 rib pre-cartilage condensation http://purl.obolibrary.org/obo/UBERON_0015019 rib endochondral element A rib endochondral element that is composed primarily of a pre-cartilage condensation. http://purl.obolibrary.org/obo/UBERON_0006290 scapula cartilage element http://purl.obolibrary.org/obo/UBERON_0015057 scapula endochondral element A scapula endochondral element that is composed primarily of cartilage tissue. http://purl.obolibrary.org/obo/GO_0110096 cellular response to aldehyde http://purl.obolibrary.org/obo/GO_1901701 cellular response to oxygen-containing compound Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aldehyde stimulus. http://purl.obolibrary.org/obo/UBERON_0006291 scapula pre-cartilage condensation http://purl.obolibrary.org/obo/UBERON_0015057 scapula endochondral element A scapula endochondral element that is composed primarily of a pre-cartilage condensation. http://purl.obolibrary.org/obo/GO_0062056 compound eye pigment cell differentiation http://purl.obolibrary.org/obo/GO_0050931 pigment cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a compound eye pigment cell, a cell of the retina containing screening pigments that functions to screen photoreceptors from light leaking from adjacent ommatidia. http://purl.obolibrary.org/obo/UBERON_0006293 spleen primordium http://purl.obolibrary.org/obo/UBERON_0003104 mesenchyme A dense syncitial-like mesenchymal thickening in the dorsal mesogastrium[ISBN]. the embryonic connective tissue made up of loosely aggregated mesenchymal cells, supported by interlaminar jelly, that gives rise to the developing spleen[MP]. http://purl.obolibrary.org/obo/GO_0150076 neuroinflammatory response http://purl.obolibrary.org/obo/GO_0006954 inflammatory response The immediate defensive reaction by neural vertebrate tissue to infection or injury caused by chemical or physical agents. http://purl.obolibrary.org/obo/UBERON_0006297 sublingual gland primordium http://purl.obolibrary.org/obo/UBERON_0017651 salivary gland primordium A primordium that has the potential to develop into a sublingual gland. http://purl.obolibrary.org/obo/GO_0150078 positive regulation of neuroinflammatory response http://purl.obolibrary.org/obo/GO_0050729 positive regulation of inflammatory response Any process that activates or increases the frequency, rate or extent of neuroinflammatory response. http://purl.obolibrary.org/obo/UBERON_0006298 submandibular gland primordium http://purl.obolibrary.org/obo/UBERON_0017651 salivary gland primordium A primordium that has the potential to develop into a submandibular gland. http://purl.obolibrary.org/obo/GO_0150079 negative regulation of neuroinflammatory response http://purl.obolibrary.org/obo/GO_0050728 negative regulation of inflammatory response Any process that stops, prevents or reduces the frequency, rate or extent of neuroinflammatory response. http://purl.obolibrary.org/obo/UBERON_0006311 chamber of eyeball http://purl.obolibrary.org/obo/UBERON_0000063 organ subunit A segment of the eyeball that is filled with refractive media. http://purl.obolibrary.org/obo/GO_0140354 lipid import into cell http://purl.obolibrary.org/obo/GO_0006869 lipid transport The directed movement of a lipid from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis. http://purl.obolibrary.org/obo/UBERON_0006312 ocular refractive media http://purl.obolibrary.org/obo/UBERON_0000463 organism substance Body substance in a liquid or semi-solid state in the eyeball which serves to refract light. http://purl.obolibrary.org/obo/GO_0150117 positive regulation of cell-substrate junction organization http://purl.obolibrary.org/obo/GO_0150116 regulation of cell-substrate junction organization Any process that activates or increases the frequency, rate or extent of cell-substrate junction organization. http://purl.obolibrary.org/obo/UBERON_0006314 bodily fluid http://purl.obolibrary.org/obo/UBERON_0000463 organism substance Liquid components of living organisms. includes fluids that are excreted or secreted from the body as well as body water that normally is not. http://purl.obolibrary.org/obo/GO_0150118 negative regulation of cell-substrate junction organization http://purl.obolibrary.org/obo/GO_0150116 regulation of cell-substrate junction organization Any process that stops, prevents or reduces the frequency, rate or extent of cell-substrate junction organization. http://purl.obolibrary.org/obo/UBERON_0006331 brainstem nucleus http://purl.obolibrary.org/obo/UBERON_0002308 nucleus of brain A nucleus of brain that is part of a brainstem. http://purl.obolibrary.org/obo/CL_0001200 lymphocyte of B lineage, CD19-positive http://purl.obolibrary.org/obo/CL_0000945 lymphocyte of B lineage A lymphocyte of B lineage that is CD19-positive. http://purl.obolibrary.org/obo/UBERON_0006334 posterior lateral line http://purl.obolibrary.org/obo/UBERON_0010202 lateral line One of eight distinct lateral lines in the 4-day larva. A sensory system on the surface of the fish, consisting of small sensory patches (neuromasts) distributed in discrete lines over the body surface. The lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the fish through the water, as well as facilitating shoaling, prey capture, and predator and obstacle avoidance. http://purl.obolibrary.org/obo/CL_0001201 B cell, CD19-positive http://purl.obolibrary.org/obo/CL_0001200 lymphocyte of B lineage, CD19-positive A B cell that is CD19-positive. http://purl.obolibrary.org/obo/UBERON_0006338 lateral ventricle choroid plexus stroma http://purl.obolibrary.org/obo/UBERON_0005206 choroid plexus stroma A choroid plexus stroma that is part of a lateral ventricle. http://purl.obolibrary.org/obo/CL_0001202 CD86-positive plasmablast http://purl.obolibrary.org/obo/CL_0000980 plasmablast A plasmablast that is CD86-positive. http://purl.obolibrary.org/obo/UBERON_0006339 third ventricle choroid plexus stroma http://purl.obolibrary.org/obo/UBERON_0005206 choroid plexus stroma A choroid plexus stroma that is part of a third ventricle. http://purl.obolibrary.org/obo/CL_0001203 CD8-positive, alpha-beta memory T cell, CD45RO-positive http://purl.obolibrary.org/obo/CL_0000909 CD8-positive, alpha-beta memory T cell A CD8-positive, alpha-beta T cell with memory phenotype indicated by being CD45RO and CD127-positive. This cell type is also described as being CD25-negative. http://purl.obolibrary.org/obo/UBERON_0006340 fourth ventricle choroid plexus stroma http://purl.obolibrary.org/obo/UBERON_0005206 choroid plexus stroma A choroid plexus stroma that is part of a fourth ventricle. http://purl.obolibrary.org/obo/CL_0001204 CD4-positive, alpha-beta memory T cell, CD45RO-positive http://purl.obolibrary.org/obo/CL_0000897 CD4-positive, alpha-beta memory T cell CD4-positive, alpha-beta long-lived T cell with the phenotype CD45RO-positive and CD127-positive. This cell type is also described as being CD25-negative. http://purl.obolibrary.org/obo/UBERON_0006341 outer renal medulla peritubular capillary http://purl.obolibrary.org/obo/UBERON_0005272 peritubular capillary A peritubular capillary that is part of a outer medulla of kidney. http://purl.obolibrary.org/obo/CL_0008033 decidual pericyte http://purl.obolibrary.org/obo/CL_2000078 placental pericyte A pericyte of the decidual vasculature. http://purl.obolibrary.org/obo/UBERON_0006347 communicating artery http://purl.obolibrary.org/obo/UBERON_0001637 artery An artery that connects two larger arteries. http://purl.obolibrary.org/obo/CL_0008034 mural cell http://purl.obolibrary.org/obo/CL_4033054 perivascular cell Mural cells are pericytes and the vascular smooth muscle cells (vSMCs) of the microcirculation. http://purl.obolibrary.org/obo/UBERON_0006376 premacula segment of distal straight tubule http://purl.obolibrary.org/obo/UBERON_0007685 region of nephron tubule Missing definition for term UBERON:0006376. Please replace it using linked reference. http://purl.obolibrary.org/obo/CL_0008035 microcirculation associated smooth muscle cell http://purl.obolibrary.org/obo/CL_0008034 mural cell Any vascular associated smooth muscle cell that is part of some microcirculatory vessel. http://purl.obolibrary.org/obo/UBERON_0006435 os penis http://purl.obolibrary.org/obo/UBERON_0007719 bone of reproductive organ The unique bone located in the glans penis of most mammals except humans; it is used for copulation and varies in size and shape by species. http://purl.obolibrary.org/obo/CL_0008036 extravillous trophoblast http://purl.obolibrary.org/obo/CL_0000351 trophoblast cell A trophoblast cell that is not part of a placental villous. http://purl.obolibrary.org/obo/UBERON_0006440 os clitoris http://purl.obolibrary.org/obo/UBERON_0007719 bone of reproductive organ The ossified region of endochondral and membranous bone located in the clitoris of most mammals except humans; it is homologous to the penile bone (aka as baculum, penis bone or os penis) in male mammals. http://purl.obolibrary.org/obo/CL_0011017 vagal neural crest cell http://purl.obolibrary.org/obo/CL_0011012 neural crest cell Cell that is part of the vagal neural crest population. The vagal neural crest arises from the axial level of somites 1-7 and has been described as a hybrid between the head and the trunk populations. http://purl.obolibrary.org/obo/UBERON_0006444 annulus fibrosus http://purl.obolibrary.org/obo/UBERON_0001995 fibrocartilage A ring of fibrous or fibrocartilaginous tissue (as of an intervertebral disk or surrounding an orifice of the heart). http://purl.obolibrary.org/obo/CL_0011020 neural progenitor cell http://purl.obolibrary.org/obo/CL_0011026 progenitor cell An undifferentiated cell derived from a neural stem cell, with a limited capacity to self-renew (Dibajnia and Morshead, 2013) and the ability to generate multiple types of lineage-restricted progenitors, contributing to the formation of neurons, astrocytes, and oligodendrocytes. http://purl.obolibrary.org/obo/UBERON_0006514 pallidum http://purl.obolibrary.org/obo/UBERON_0003528 brain gray matter Part of what are called the basal ganglia of the brain which consist of the globus pallidus and the ventral pallidum. http://purl.obolibrary.org/obo/CL_0017000 pulmonary ionocyte http://purl.obolibrary.org/obo/CL_0005006 ionocyte An ionocyte that is part of the lung epithelium. The cells from this type are major sources of the CFTR protein in human and mice. http://purl.obolibrary.org/obo/UBERON_0006516 dorsal pallidum http://purl.obolibrary.org/obo/UBERON_0006514 pallidum The predominant portion of the globus pallidus in the striatopallidal system, which is defined by connectivity and neurochemical staining. The dorsal pallidum is distinguished from the ventral pallidum by a boundary that is partially defined by the anterior commissure. The remainder of the boundary is indistinct in sections stained for Nissl substance ( Heimer-1995 ). http://purl.obolibrary.org/obo/CL_0017001 splanchnic mesodermal cell http://purl.obolibrary.org/obo/CL_0011010 lateral mesodermal cell A mesodermal cell that is part of the splanchnic layer of lateral plate mesoderm. http://purl.obolibrary.org/obo/UBERON_0006518 right lung lobe http://purl.obolibrary.org/obo/UBERON_0000101 lobe of lung A lobe of lung that is part of a right lung. http://purl.obolibrary.org/obo/PATO_0070018 tufted pyramidal morphology http://purl.obolibrary.org/obo/PATO_0070017 standard pyramidal morphology A pyramidal cell morphology that inheres in neurons which have a distinct tuft formation, distal from the soma. http://purl.obolibrary.org/obo/UBERON_0006524 alveolar system http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision System pertaining to a bronchus and alveoli. http://purl.obolibrary.org/obo/UBERON_0006530 seminal fluid http://purl.obolibrary.org/obo/UBERON_0006536 male reproductive gland secretion A substance formed from the secretion of one or more glands of the male genital tract in which sperm cells are suspended. http://purl.obolibrary.org/obo/PATO_0070015 pyramidal family morphology http://purl.obolibrary.org/obo/PATO_0070026 multipolar neuron morphology A cell morphology that inheres in neurons which have a pyramidal shaped soma, a single axon, a large apical dendrite and multiple basal dendrites. http://purl.obolibrary.org/obo/UBERON_0006534 renal convoluted tubule http://purl.obolibrary.org/obo/UBERON_0007685 region of nephron tubule Any region of a nephron tubule that is convoluted. Examples: distal convoluted tubule, proximal convoluted tuble. http://purl.obolibrary.org/obo/CL_4023046 L6b glutamatergic neuron of the primary motor cortex http://purl.obolibrary.org/obo/CL_4023038 L6b glutamatergic cortical neuron An excitatory glutamatergic neuron transcriptomically related to the CT subclass, with a soma preferentially located in the bottom of L6 of the primary motor cortex. http://purl.obolibrary.org/obo/UBERON_0006535 skin secretion http://purl.obolibrary.org/obo/UBERON_0000463 organism substance A portion of organism substance that secreted_by a zone of skin. http://purl.obolibrary.org/obo/CL_4023095 untufted pyramidal neuron http://purl.obolibrary.org/obo/CL_0000598 pyramidal neuron A pyramidal neuron which lacks a clear tuft formation but extends to large radial distances. http://purl.obolibrary.org/obo/UBERON_0006536 male reproductive gland secretion http://purl.obolibrary.org/obo/UBERON_0022293 reproductive gland secretion A portion of organism substance that is secreted by a male reproductive gland. http://purl.obolibrary.org/obo/GO_0120327 telopode http://purl.obolibrary.org/obo/GO_0120025 plasma membrane bounded cell projection A telopode is a plasma membrane bounded cell projection that is present on a telocyte and is tens to hundreds of microns long. Telopodes form a labyrinthine system communicating through gap junctions. http://purl.obolibrary.org/obo/UBERON_0006537 female reproductive gland secretion http://purl.obolibrary.org/obo/UBERON_0022293 reproductive gland secretion A portion of organism substance that is secreted by a female reproductive gland. http://purl.obolibrary.org/obo/CL_0017500 neutrophillic cytoplasm http://purl.obolibrary.org/obo/GO_0005737 cytoplasm Cytoplasm that exhibits a characteristic staining and color, pale-pink, with Wright-Giemsa stain. http://purl.obolibrary.org/obo/UBERON_0006538 respiratory system fluid/secretion http://purl.obolibrary.org/obo/UBERON_0000463 organism substance A portion of organism substance that secreted_by a respiratory system. http://purl.obolibrary.org/obo/CL_0017502 acidophilic cytoplasm http://purl.obolibrary.org/obo/GO_0005737 cytoplasm Cytoplasm that exhibits a characteristic staining and color, red or pink, with Eosin stain. http://purl.obolibrary.org/obo/UBERON_0006539 mammary gland fluid/secretion http://purl.obolibrary.org/obo/UBERON_0000456 secretion of exocrine gland A substance that is secreted by a mammary gland. The substance may differ depending on phase, with colostrum produced during pregancy/early lactation, and milk produced afterwards. http://purl.obolibrary.org/obo/CL_0017503 basophilic cytoplasm http://purl.obolibrary.org/obo/GO_0005737 cytoplasm Cytoplasm that exhibits molecular interaction for basic dyes under specific pH conditions. http://purl.obolibrary.org/obo/UBERON_0006541 outer medulla inner stripe loop of Henle http://purl.obolibrary.org/obo/UBERON_0034996 outer renal medulla loop of Henle A loop of Henle that is part of a kidney outer medulla inner stripe. http://purl.obolibrary.org/obo/CL_0017504 polychromatophilic cytoplasm http://purl.obolibrary.org/obo/GO_0005737 cytoplasm Cytoplasm that exhibits affinity for both basic and acid stains under specific pH conditions. http://purl.obolibrary.org/obo/CL_0017507 reniform nucleus http://purl.obolibrary.org/obo/GO_0005634 nucleus A concave nucleus shape where the indentation is smaller than half of the distance to the farthest nuclear margin. http://purl.obolibrary.org/obo/UBERON_0006542 outer medulla outer stripe loop of Henle http://purl.obolibrary.org/obo/UBERON_0034996 outer renal medulla loop of Henle A loop of Henle that is part of a kidney outer medulla outer stripe. http://purl.obolibrary.org/obo/CL_0017509 alobate nucleus http://purl.obolibrary.org/obo/GO_0005634 nucleus Any nucleus that has characteristic some alobate. http://purl.obolibrary.org/obo/UBERON_0006544 kidney vasculature http://purl.obolibrary.org/obo/UBERON_0006876 vasculature of organ A vasculature that is part of a kidney. http://purl.obolibrary.org/obo/UBERON_8410077 airway submucosal gland http://purl.obolibrary.org/obo/UBERON_0036225 respiratory system gland A submucosal gland found in a respiratory tract. http://purl.obolibrary.org/obo/UBERON_0006553 renal duct http://purl.obolibrary.org/obo/UBERON_0000058 duct A tube in the kidney that collect and transport urine. http://purl.obolibrary.org/obo/UBERON_0039856 right ovarian vein http://purl.obolibrary.org/obo/UBERON_0001145 ovarian vein Ovarian vein, each instance of which is a tributary of some inferior vena cava that drains the right pampiniform plexus of some broad ligament. http://purl.obolibrary.org/obo/UBERON_0006555 excretory tube http://purl.obolibrary.org/obo/UBERON_0000025 tube A tube that is part of a excretory system. http://purl.obolibrary.org/obo/UBERON_0039857 left ovarian vein http://purl.obolibrary.org/obo/UBERON_0001145 ovarian vein Ovarian vein, each instance of which is a tributary of some left renal vein that drains the left pampiniform plexus of some broad ligament. http://purl.obolibrary.org/obo/UBERON_0006561 non-lymphatic part of lymphoid system http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision An organ system subdivision that is the part of the lymphoid system that excludes the lymphatic vessels.. http://purl.obolibrary.org/obo/UBERON_8440008 periventricular hypothalamic nucleus, intermediate part http://purl.obolibrary.org/obo/UBERON_0006568 hypothalamic nucleus The intermediate part of the periventricular hypothalamic nucleus. http://purl.obolibrary.org/obo/UBERON_0006563 tunica media of pulmonary trunk http://purl.obolibrary.org/obo/UBERON_0007239 tunica media of artery Tunica media of artery which is continuous with the myocardium of right ventricle.[FMA]. http://purl.obolibrary.org/obo/UBERON_8440012 cerebral nuclei http://purl.obolibrary.org/obo/UBERON_0009663 telencephalic nucleus One of three components of the cerebrum that is a composite structure of the endbrain defined on the basis of origin from the ventricular ridge of the embryonic Encephalon. It consists of the extended striatum and the extended pallidum. http://purl.obolibrary.org/obo/UBERON_0006565 female urethral meatus http://purl.obolibrary.org/obo/UBERON_0012240 urethral meatus A urethral meatus that is part of a female urethra[Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_8440030 striatum-like amygdalar nuclei http://purl.obolibrary.org/obo/UBERON_0009663 telencephalic nucleus A part of the striatum which is primarilly composed of amygdalar areas. The sAMY is composed of the anterior amygdalar area, central amygdalar nucleus, intercalated amygdalar nucleus, medial amygdalar nucleus, and the bed nucleus of the accessory olfactory tract. http://purl.obolibrary.org/obo/UBERON_0006566 left ventricle myocardium http://purl.obolibrary.org/obo/UBERON_0001083 myocardium of ventricle A myocardium that is part of a left ventricle of a heart. http://purl.obolibrary.org/obo/UBERON_8440043 superior paraolivary nucleus http://purl.obolibrary.org/obo/UBERON_0007247 nucleus of superior olivary complex A structure embedded in the superior olivary complex that is driven by input pathways from the octopus cells in the cochlear nucleus and the neurons of the medial nucleus of the trapezoid body. http://purl.obolibrary.org/obo/UBERON_0006567 right ventricle myocardium http://purl.obolibrary.org/obo/UBERON_0001083 myocardium of ventricle A myocardium that is part of a right ventricle of a heart. http://purl.obolibrary.org/obo/CL_0017005 lymphoblast http://purl.obolibrary.org/obo/CL_0000542 lymphocyte A lymphocyte that has gotten larger after being stimulated by an antigen. http://purl.obolibrary.org/obo/UBERON_0006568 hypothalamic nucleus http://purl.obolibrary.org/obo/UBERON_0006569 diencephalic nucleus A nucleus of brain that is part of a hypothalamus. http://purl.obolibrary.org/obo/CL_4030027 GABAergic amacrine cell http://purl.obolibrary.org/obo/CL_0011005 GABAergic interneuron An amacrine cell that uses GABA as a neurotransmitter. http://purl.obolibrary.org/obo/UBERON_0006569 diencephalic nucleus http://purl.obolibrary.org/obo/UBERON_0002308 nucleus of brain A nucleus of brain that is part of a diencephalon. http://purl.obolibrary.org/obo/CL_4030028 glycinergic amacrine cell http://purl.obolibrary.org/obo/CL_1001509 glycinergic neuron An amacrine cell that uses glycine as a neurotransmitter. http://purl.obolibrary.org/obo/UBERON_0006570 trabecula carnea of right ventricle http://purl.obolibrary.org/obo/UBERON_0002511 trabecula carnea A trabecula carnea that is part of a heart right ventricle. http://purl.obolibrary.org/obo/CL_0003004 G3 retinal ganglion cell http://purl.obolibrary.org/obo/CL_0003001 bistratified retinal ganglion cell A bistratified retinal ganglion cell that has a small dendritic field with sparse density that terminates at the intersection of the S4-S5 sublaminar level, and a second dendrite field that is medium in size and degree of arborization that terminates in sublaminar layer S2. http://purl.obolibrary.org/obo/UBERON_0006571 trabecula carnea of left ventricle http://purl.obolibrary.org/obo/UBERON_0002511 trabecula carnea A trabecula carnea that is part of a heart left ventricle. http://purl.obolibrary.org/obo/CL_0003001 bistratified retinal ganglion cell http://purl.obolibrary.org/obo/CL_0004247 bistratified cell A retinal ganglion cell that has dendrites stratified in two layers of the inner-plexiform layer. http://purl.obolibrary.org/obo/UBERON_0006574 pectinate line http://purl.obolibrary.org/obo/UBERON_8410024 intestinal junction The pectinate line (anocutaneous line, dentate line, anorectal junction) is a line which divides the upper 2/3rds and lower 1/3rd of the anal canal. Developmentally, this line represents the hindgut-proctodeum junction. It is an important anatomical landmark, and several distinctions can be made based upon the location of a structure relative to this line:. http://purl.obolibrary.org/obo/PATO_0070063 monostratified dendrite cell morphology http://purl.obolibrary.org/obo/PATO_0010006 cell morphology A cell morphology that inheres in neurons with dendrites that stratify at one and only one location. http://purl.obolibrary.org/obo/UBERON_0006585 vestibular organ http://purl.obolibrary.org/obo/UBERON_0000062 organ An organ that is part of a vestibular system. http://purl.obolibrary.org/obo/GO_0140962 multicellular organismal-level chemical homeostasis http://purl.obolibrary.org/obo/GO_0048878 chemical homeostasis A homeostatic process involved in the maintenance of a steady state level of a chemical within extracellular body fluids, such as blood, xylem or phloem, of a multicellular organism. This is distinct from maintenance of cellular homeostasis, which occurs within a cell. http://purl.obolibrary.org/obo/UBERON_0006586 otolymph http://purl.obolibrary.org/obo/UBERON_0007779 transudate Transudate located within the osseus labyrinth. Otolymph can be further classified with respect to whether it is within the membranous labyrinth (endolymph) or outside the mebranous labyrinth (perilymph). http://purl.obolibrary.org/obo/CL_4033001 endothelial cell of arteriole of lymph node http://purl.obolibrary.org/obo/CL_1000412 endothelial cell of arteriole A(n) endothelial cell that is part of a(n) arteriole of lymph node. http://purl.obolibrary.org/obo/UBERON_0006595 presumptive endoderm http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure Presumptive structure of the blastula that will develop into endoderm. http://purl.obolibrary.org/obo/STATO_0000607 proportion http://purl.obolibrary.org/obo/STATO_0000184 ratio a proportion is a ratio which corresponds to the fraction of the total presenting a particular feature http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure Portion of embryonic tissue determined by fate mapping to become a structure. http://purl.obolibrary.org/obo/STATO_0000610 measure of association http://purl.obolibrary.org/obo/STATO_0000039 statistic measure of association is a statistic which quantitatively represents a relationship between two or more variables http://purl.obolibrary.org/obo/UBERON_0006601 presumptive ectoderm http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure Presumptive structure of the blastula that will develop into ectoderm. http://purl.obolibrary.org/obo/STATO_0000623 measure of agreement http://purl.obolibrary.org/obo/STATO_0000610 measure of association A measure of association of two variables representing measurements of the same attribute of an entity. http://purl.obolibrary.org/obo/UBERON_0006603 presumptive mesoderm http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure Presumptive structure of the blastula that will develop into mesoderm. http://purl.obolibrary.org/obo/CL_4033126 sacral ganglion TH neuron http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron A sympathetic neuron that has the soma located in the sacral ganglion and expresses the marker tyrosine hydroxylase (TH). http://purl.obolibrary.org/obo/UBERON_0006606 mandibular symphysis http://purl.obolibrary.org/obo/UBERON_0002216 symphysis A cartilaginous joint that connects left and right mandibles/dentary bones. Mandibular symphysis is unpaired[TAO,modified]. http://purl.obolibrary.org/obo/CL_4301591 Astro-TE NN_1 astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4300359 astrocyte of cerebrum (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Myoc (Mmus), Camk2a (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1161 Astro-TE NN_1. http://purl.obolibrary.org/obo/UBERON_0006614 aponeurosis http://purl.obolibrary.org/obo/UBERON_0000158 membranous layer A sheet of extracellular matrix. http://purl.obolibrary.org/obo/CL_4307083 hypendemal cell (Mmus) http://purl.obolibrary.org/obo/CL_4023181 hypendymal cell A hypendymal cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Sspo (Mmus), Wfdc2 (Mmus). It is distinguished from other Astro-Epen cells by expression of Sspo, Wfdc2. These cells are located in the Midbrain, brain , in or close to the regions: third ventricle, posterior commissure, Subcommissural organ . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5263 Hypendymal NN_1. http://purl.obolibrary.org/obo/UBERON_0006615 venous sinus http://purl.obolibrary.org/obo/UBERON_0003920 venous blood vessel A large vein or channel for the circulation of venous blood. http://purl.obolibrary.org/obo/CL_4072008 A11 dopaminergic neuron http://purl.obolibrary.org/obo/CL_0012001 neuron of the forebrain A type of hypothalamic dopaminergic neuron found in the posterior hypothalamus, projecting to the spinal cord where it modulates pain, motor activity (Koblinger et al., 2014), and somatosensory processing (Zhang et a., 2023). http://purl.obolibrary.org/obo/UBERON_0006616 right external ear http://purl.obolibrary.org/obo/UBERON_0001691 external ear An external ear that is in the right side of a multicellular organism. http://purl.obolibrary.org/obo/CL_4072007 A10 dopaminergic neuron http://purl.obolibrary.org/obo/CL_2000097 midbrain dopaminergic neuron A type of dopaminergic neuron found in the ventral tegmental area that is involved in reward processes, motivation and addiction. http://purl.obolibrary.org/obo/UBERON_0006617 left external ear http://purl.obolibrary.org/obo/UBERON_0001691 external ear An external ear that is in the left side of a multicellular organism. http://purl.obolibrary.org/obo/CL_4072012 A15 dopaminergic neuron http://purl.obolibrary.org/obo/CL_0012001 neuron of the forebrain A type of dopaminergic neuron located in the preoptic periventricular nucleus of the hypothalamus and implicated in neuroendocrine modulation. http://purl.obolibrary.org/obo/UBERON_0006632 musculo-phrenic artery http://purl.obolibrary.org/obo/UBERON_0002057 phrenic artery An artery with its origin in the lateral terminal branch of the internal thoracic artery, with distribution to the diaphragm and the intercostal muscles, and with anastomoses to the branches of the pericardiacophrenic and inferior phrenic. http://purl.obolibrary.org/obo/CL_4307036 Astro-NT NN_2 Fam227b astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301590 Astro-NT NN_2 astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Slc7a10 (Mmus), Cyp26b1 (Mmus), Igfbp2 (Mmus), Shroom3 (Mmus). It is distinguished from other Astro-NT NN_2 cells by expression of Fam227b, Shroom3. These cells are located in the Midbrain, Medulla, Pons . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5216 Astro-NT NN_2. http://purl.obolibrary.org/obo/UBERON_0006642 muscle layer of oviduct http://purl.obolibrary.org/obo/UBERON_0006660 muscular coat A muscle layer that is part of a fallopian tube. http://purl.obolibrary.org/obo/CL_4300351 CBX MLI Megf11 Gaba molecular layer interneuron (Mmus) http://purl.obolibrary.org/obo/CL_4300028 cerebellar GABAergic neuron (Mmus) A molecular layer interneuron of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Homer3 (Mmus), Tfap2b (Mmus), Sorcs3 (Mmus), Cacna1e (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Subclass:311 CBX MLI Megf11 Gaba. http://purl.obolibrary.org/obo/UBERON_0006645 adventitia of epididymis http://purl.obolibrary.org/obo/UBERON_0005742 adventitia An adventitia that is part of a epididymis. http://purl.obolibrary.org/obo/CL_4072003 mature myelinating oligodendrocyte http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure A post-mitotic oligodendrocyte derived from a myelin-forming oligodendrocyte (MFOL). A mature Myelinating Oligodendrocyte is a fully differentiated cell that is actively engaged in myelination. In addition to high expression of canonical myelin genes (e.g., Mbp, Plp1, Mog), a MOL can be distinguished by the expression of stage-enriched genes Grm3, Klk6, Ptgds, Anxa5, and Hopx in mice. These markers reflect the functional specialization of a mature oligodendrocyte, including roles in signalling, lipid metabolism, and myelin maintenance. http://purl.obolibrary.org/obo/UBERON_0006646 muscle layer of epididymis http://purl.obolibrary.org/obo/UBERON_0006660 muscular coat A muscle layer that is part of a epididymis. http://purl.obolibrary.org/obo/CL_4306426 pinealocyte (Mmus) http://purl.obolibrary.org/obo/CL_0000652 pinealocyte A pinealocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Cngb3 (Mmus), Ush2a (Mmus). It is glutamatergic (inferred from expression of Ddc, Slc17a6, Slc17a7). These cells are located in the brain , in or close to the regions: third ventricle . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:4606 Pineal Crx Glut_1. http://purl.obolibrary.org/obo/UBERON_0006647 adventitia of ductus deferens http://purl.obolibrary.org/obo/UBERON_0005742 adventitia An adventitia that is part of a vas deferens. http://purl.obolibrary.org/obo/GO_0140115 export across plasma membrane http://purl.obolibrary.org/obo/GO_0055085 transmembrane transport The directed movement of some substance from inside of a cell, across the plasma membrane and into the extracellular region. http://purl.obolibrary.org/obo/UBERON_0006648 adventitia of seminal vesicle http://purl.obolibrary.org/obo/UBERON_0005742 adventitia An adventitia that is part of a seminal vesicle. http://purl.obolibrary.org/obo/UBERON_0036285 wall of left ventricle http://purl.obolibrary.org/obo/UBERON_0004784 heart ventricle wall Wall of ventricle which is continuous with the wall of aorta. http://purl.obolibrary.org/obo/UBERON_0006653 glans clitoris http://purl.obolibrary.org/obo/UBERON_0008324 erectile tissue Erectile tissue at the end of the clitoris, which is continuous with the intermediate part of the vestibulovaginal bulbs[BTO]. The clitoral glans (glans clitoridis) is an external portion of the clitoris[WP]. http://purl.obolibrary.org/obo/UBERON_0036286 wall of right ventricle http://purl.obolibrary.org/obo/UBERON_0004784 heart ventricle wall Wall of ventricle which is continuous with the wall of pulmonary trunk. http://purl.obolibrary.org/obo/UBERON_0006657 glenoid fossa http://purl.obolibrary.org/obo/UBERON_0004704 bone fossa Anatomical cavity for the proximal articular surface of the proximal limb or fin element with the scapulocoracoid or equivalent structure. http://purl.obolibrary.org/obo/UBERON_0036294 mucosa of lip http://purl.obolibrary.org/obo/UBERON_0003729 mouth mucosa A mucosa that is part of a lip region [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0006658 interphalangeal joint http://purl.obolibrary.org/obo/UBERON_0011139 synovial limb joint A joint that connects one phalanx to another along a proximodistal axis. http://purl.obolibrary.org/obo/GO_0150147 cell-cell junction disassembly http://purl.obolibrary.org/obo/GO_0045216 cell-cell junction organization The disaggregation of a cell-cell junction into its constituent components. http://purl.obolibrary.org/obo/UBERON_0006660 muscular coat http://purl.obolibrary.org/obo/UBERON_0018260 layer of muscle tissue A region of muscle in many organs in the vertebrate body, adjacent to the submucosa membrane. It is responsible for gut movement such as peristalsis. http://purl.obolibrary.org/obo/GO_0062197 cellular response to chemical stress http://purl.obolibrary.org/obo/GO_0070887 cellular response to chemical stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus indicating the organism is under stress. http://purl.obolibrary.org/obo/UBERON_0006661 epicranial aponeurosis http://purl.obolibrary.org/obo/UBERON_0006614 aponeurosis The galea aponeurotica (epicranial aponeurosis, aponeurosis epicranialis) is a tough layer of dense fibrous tissue which covers the upper part of the cranium; behind, it is attached, in the interval between its union with the Occipitales, to the external occipital protuberance and highest nuchal lines of the occipital bone; in front, it forms a short and narrow prolongation between its union with the Frontales. On either side it gives origin to the Auriculares anterior and superior; in this situation it loses its aponeurotic character, and is continued over the temporal fascia to the zygomatic arch as a layer of laminated areolar tissue. It is closely connected to the integument by the firm, dense, fibro-fatty layer which forms the superficial fascia of the scalp: it is attached to the pericranium by loose cellular tissue, which allows the aponeurosis, carrying with it the integument to move through a considerable distance. http://purl.obolibrary.org/obo/GO_0120223 larynx morphogenesis http://purl.obolibrary.org/obo/GO_0009887 animal organ morphogenesis The process in which the larynx is generated and organized. The larynx is a continuation of the pharynx that is involved in breathing, sound production, and protecting the trachea against food aspiration. http://purl.obolibrary.org/obo/UBERON_0006668 carotid canal http://purl.obolibrary.org/obo/UBERON_0013685 foramen of skull On the interior surface of the temporal bone, behind the rough surface of the apex, is the large circular aperture of the carotid canal, which ascends at first vertically, and then, making a bend, runs horizontally forward and medialward. It transmits into the cranium, the internal carotid artery, and the carotid plexus of nerves. Sympathetics to the head also pass through the carotid canal. They have several motor functions: raise the eyelid (superior tarsal muscle), dilate pupil, innervate sweat glands of face and scalp and constricts blood vessels in head[WP]. http://purl.obolibrary.org/obo/GO_0120224 larynx development http://purl.obolibrary.org/obo/GO_0048513 animal organ development The biological process whose specific outcome is the progression of a larynx from an initial condition to its mature state. This process begins with the formation of the larynx and ends with the mature structure. A larynx is a continuation of the pharynx that is involved in breathing, sound production, and protecting the trachea against food aspiration. http://purl.obolibrary.org/obo/UBERON_0006670 central tendon of diaphragm http://purl.obolibrary.org/obo/UBERON_0003837 thoracic segment connective tissue The three-lobed cloverleaf-shaped aponeurosis situated at the center of the diaphragm; the central tendon is fused with the fibrous pericardium that provides attachment for the muscle fibers. http://purl.obolibrary.org/obo/PR_000050025 angiotensinogenase http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the mouse Ren1 or Ren2 genes, 1:1 orthologs thereof, or a semi-ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0006675 venous valve http://purl.obolibrary.org/obo/UBERON_0003978 valve A valve that is part of a vein. http://purl.obolibrary.org/obo/CL_0011019 mesothelial cell of epicardium http://purl.obolibrary.org/obo/CL_0002494 cardiocyte A mesothelial cell that is part of the epicardium. http://purl.obolibrary.org/obo/UBERON_0006676 muscularis mucosa http://purl.obolibrary.org/obo/UBERON_0004226 gastrointestinal system smooth muscle A thin layer of smooth muscle found in most parts of the gastrointestinal tract, located outside the lamina propria mucosae and separating it from the submucosa[WP]. http://purl.obolibrary.org/obo/CL_0011021 fibroblast of upper back skin http://purl.obolibrary.org/obo/CL_0011022 fibroblast of skin of back A fibroblast that is part of upper back skin. http://purl.obolibrary.org/obo/UBERON_0006677 surface of epithelium http://purl.obolibrary.org/obo/UBERON_0036215 anatomical surface region An anatomical boundary that adjacent_to a epithelium. http://purl.obolibrary.org/obo/UBERON_0006682 hypoglossal canal http://purl.obolibrary.org/obo/UBERON_0013685 foramen of skull The hypoglossal canal is a bony canal in the occipital bone of the skull. http://purl.obolibrary.org/obo/UBERON_0006686 spinal vein http://purl.obolibrary.org/obo/UBERON_0001638 vein A vein that is part of a vertebral column. http://purl.obolibrary.org/obo/UBERON_0006692 vertebral canal http://purl.obolibrary.org/obo/UBERON_0004111 anatomical conduit A conduit enclosed within the vertebral foramen of the vertebrae through which the spinal cord passes. http://purl.obolibrary.org/obo/UBERON_0006694 cerebellum vasculature http://purl.obolibrary.org/obo/UBERON_0036303 vasculature of central nervous system A vasculature that is part of a cerebellum. http://purl.obolibrary.org/obo/UBERON_0006716 mesopodium region http://purl.obolibrary.org/obo/UBERON_0002529 limb segment The third segment of the limb, including either the wrist segment (carpus) or the ankle segment (tarsus). http://purl.obolibrary.org/obo/UBERON_0006717 autopodial skeleton http://purl.obolibrary.org/obo/UBERON_0010712 limb skeleton subdivision The collection of all skeletal elements in an autopodium region. http://purl.obolibrary.org/obo/UBERON_0006723 cochlear modiolus http://purl.obolibrary.org/obo/UBERON_0005913 zone of bone organ The central cone shaped core of spongy bone about which turns the spiral canal. http://purl.obolibrary.org/obo/UBERON_0006725 spiral ligament http://purl.obolibrary.org/obo/UBERON_0008845 nonskeletal ligament A spiral thickening of the fibrous lining of the cochlear wall. Spiral ligament secures the membranous cochlear duct to the bony spiral canal of the cochlea. Its spiral ligament fibrocytes function in conjunction with the stria vascularis to mediate cochlear ion homeostasis. http://purl.obolibrary.org/obo/CL_0011022 fibroblast of skin of back http://purl.obolibrary.org/obo/CL_0002620 skin fibroblast A fibroblast that is part of skin of back. http://purl.obolibrary.org/obo/UBERON_0006756 median lingual swelling http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure During the third week of embryological development there appears, immediately behind the ventral ends of the two halves of the mandibular arch, a rounded swelling named the tuberculum impar, which was described by His as undergoing enlargement to form the buccal part of the tongue. More recent researches, however, show that this part of the tongue is mainly, if not entirely, developed from a pair of lateral swellings which rise from the inner surface of the mandibular arch and meet in the middle line. The site of their meeting remains post-embryonically as the median sulcus of the tongue. The tuberculum impar is said to form the central part of the tongue immediately in front of the foramen cecum, but Hammar insists that it is purely a transitory structure and forms no part of the adult tongue[WP, Gray's]. http://purl.obolibrary.org/obo/CL_0011023 CD25+ mast cell http://purl.obolibrary.org/obo/CL_0001063 neoplastic cell A mast cell that is CD25+. http://purl.obolibrary.org/obo/UBERON_0006757 lateral lingual swelling http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure During the third week there appears, immediately behind the ventral ends of the two halves of the mandibular arch, a rounded swelling named the tuberculum impar, which was described by His as undergoing enlargement to form the buccal part of the tongue. More recent researches, however, show that this part of the tongue is mainly, if not entirely, developed from a pair of lateral swellings (or distal tongue bud) which rise from the inner surface of the mandibular arch and meet in the middle line. http://purl.obolibrary.org/obo/CL_0011024 double negative T regulatory cell http://purl.obolibrary.org/obo/CL_0002489 double negative thymocyte A double negative thymocyte that is CD3-positive, CD4-negative, CD8-negative, that that are present in the periphery in very low numbers and predominantly produce INF-gamma, TNF-alpha, and a low amount of TGF-beta, but not IL-2, IL-4, IL-10 or IL-13 upon activation. http://purl.obolibrary.org/obo/UBERON_0006761 corneo-scleral junction http://purl.obolibrary.org/obo/UBERON_0007651 anatomical junction The edge of the cornea where it joins the sclera; the limbus is a common site for the occurrence of corneal epithelial neoplasm. http://purl.obolibrary.org/obo/CL_0019001 tracheobronchial serous cell http://purl.obolibrary.org/obo/CL_0000313 serous secreting cell Any serous secreting cell that is part of the tracheobronchial epithelium. http://purl.obolibrary.org/obo/UBERON_0006763 epithelium of conjunctiva http://purl.obolibrary.org/obo/UBERON_0015808 eye epithelium Layer of nonkeratinized squamous epithelium lining the conjunctiva, overlying scleral tissue. http://purl.obolibrary.org/obo/CL_0019002 tracheobronchial chondrocyte http://purl.obolibrary.org/obo/CL_0000138 chondrocyte Any chondrocyte that is part of the tracheobronchial tree. http://purl.obolibrary.org/obo/UBERON_0006799 glandular epithelium http://purl.obolibrary.org/obo/UBERON_0000483 epithelium An epithelium that is composed primarily of secretory cells. http://purl.obolibrary.org/obo/CL_0019003 tracheobronchial goblet cell http://purl.obolibrary.org/obo/CL_0002370 respiratory tract goblet cell Any goblet cell that is part of the tracheobronchial epithelium. http://purl.obolibrary.org/obo/UBERON_0006813 nasal skeleton http://purl.obolibrary.org/obo/UBERON_0010912 subdivision of skeleton Structural framework that provides support to the nasal sacs and ducts. http://purl.obolibrary.org/obo/CL_4023044 non-medulla, extratelencephalic-projecting glutamatergic neuron of the primary motor cortex http://purl.obolibrary.org/obo/CL_2000049 primary motor cortex pyramidal cell An extratelencephalic-projecting glutamatergic neuron located in layer 5b of the primary motor cortex that does not project to the medulla. Non-MY ET cells are large, big-tufted cells with the apical dendrite often bifurcating close to the soma, suggesting they are corticospinal cells. Non-MY ET cells have bigger hyperpolarization sag, lower input resistance, and smaller AP width, compared to L5 IT neurons. http://purl.obolibrary.org/obo/UBERON_0006815 areolar connective tissue http://purl.obolibrary.org/obo/UBERON_0011825 loose connective tissue Loose connective tissue located at the outer and inner layers of organs. Examples: submucosal connective tissue, tunica adventitia of artery, papillary dermis, superficial fascia of dorsum of hand. http://purl.obolibrary.org/obo/CL_4023041 L5 extratelencephalic projecting glutamatergic cortical neuron http://purl.obolibrary.org/obo/CL_4023111 cerebral cortex pyramidal neuron A transcriptomically distinct glutamatergic neuron, with a soma found in the deeper portion of L5, that has long-range axonal projections including deep subcortical targets outside of the telencephalon and, in some cases, the spinal cord. While the L5 ET neuron projections are not limited to ET targets, they are clearly differentiated from the neuron subclasses whose projections are constrained to intratelencephalic (IT) targets. L5 ET neurons are generally the largest excitatory cortical neurons, typically having a thick apical dendrite with a prominent dendritic tuft in layer 1 and displaying burst-firing physiological characteristics. http://purl.obolibrary.org/obo/UBERON_0006828 trabecula carnea of atrium http://purl.obolibrary.org/obo/UBERON_0002511 trabecula carnea The supporting bundles of muscular fibers lining the walls of the atria[MP]. http://purl.obolibrary.org/obo/CL_4023129 retinoblast http://purl.obolibrary.org/obo/CL_0009004 retinal cell A retinal cell that is immature or undifferentiated. http://purl.obolibrary.org/obo/UBERON_0006832 lumen of open tracheal system trachea http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space An anatomical space that surrounded_by a open tracheal system trachea. http://purl.obolibrary.org/obo/CL_4030000 choroidal melanocyte http://purl.obolibrary.org/obo/CL_0000148 melanocyte A melanocyte located in the vascular uvea and involved in photoprotection, regulation of oxidative damage and immune responses. http://purl.obolibrary.org/obo/UBERON_0006833 lumen of trachea http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space An anatomical space that surrounded_by a trachea. http://purl.obolibrary.org/obo/CL_4030002 effector memory CD45RA-positive, alpha-beta T cell, terminally differentiated http://purl.obolibrary.org/obo/CL_0000791 mature alpha-beta T cell An alpha-beta memory T cell with the phenotype CD45RA-positive. http://purl.obolibrary.org/obo/UBERON_0006834 uterus or analog http://purl.obolibrary.org/obo/UBERON_0013522 subdivision of tube A subdivision of a the reproductive tract in a female organism that is the site of embryo development. http://purl.obolibrary.org/obo/CL_0009102 lymph node fibroblastic reticular cell http://purl.obolibrary.org/obo/CL_0009101 fibroblastic reticular cell A specialized, fibroblastic reticular cell of mesenchymal origin found in lymph nodes. In human, it expresses several markers common to myofibroblasts (desmin, vimentin, CD73, CD90, α-smooth muscle actin (αSMA)), and can be differentiated from endothelial cells by its lack of CD31 expression. These cells are critical for the overall organization and function of the lymph node. Lymph node fibroblastic reticular cells (FRCs) can be further classified based on their location, function, and unique marker expression. http://purl.obolibrary.org/obo/UBERON_0006841 central vein of liver http://purl.obolibrary.org/obo/UBERON_0015796 liver blood vessel Vein that is central to a lobule in the liver. http://purl.obolibrary.org/obo/GO_0106426 regulation of kainate selective glutamate receptor signaling pathway http://purl.obolibrary.org/obo/GO_1900449 regulation of glutamate receptor signaling pathway Any process that modulates the frequency, rate or extent of the kainate selective glutamate receptor signaling pathway. http://purl.obolibrary.org/obo/UBERON_0006843 root of cranial nerve http://purl.obolibrary.org/obo/UBERON_0011215 central nervous system cell part cluster The initial segment of a cranial nerve, leaving the central nervous system. http://purl.obolibrary.org/obo/GO_0106427 negative regulation of kainate selective glutamate receptor signaling pathway http://purl.obolibrary.org/obo/GO_0106426 regulation of kainate selective glutamate receptor signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of the kainate selective glutamate receptor signaling pathway. http://purl.obolibrary.org/obo/UBERON_0006846 surface groove http://purl.obolibrary.org/obo/UBERON_0000466 immaterial anatomical entity A furrow or an incomplete tube. http://purl.obolibrary.org/obo/GO_0106428 positive regulation of kainate selective glutamate receptor signaling pathway http://purl.obolibrary.org/obo/GO_0106426 regulation of kainate selective glutamate receptor signaling pathway Any process that activates or increases the frequency, rate or extent of the kainate selective glutamate receptor signaling pathway. http://purl.obolibrary.org/obo/UBERON_0006847 cerebellar commissure http://purl.obolibrary.org/obo/UBERON_0001020 nervous system commissure A nervous system commissure that connects a left hemisphere of cerebellum and connects a right hemisphere of cerebellum. http://purl.obolibrary.org/obo/GO_0140899 plastid gene expression http://purl.obolibrary.org/obo/GO_0010467 gene expression The process in which a plastid gene's sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form. http://purl.obolibrary.org/obo/UBERON_0006849 scapula http://purl.obolibrary.org/obo/UBERON_0015057 scapula endochondral element Endochondral bone that is dorsoventrally compressed and provides attachment site for muscles of the pectoral appendage. http://purl.obolibrary.org/obo/GO_0160038 somatic sensory system development http://purl.obolibrary.org/obo/GO_0048880 sensory system development The process whose specific outcome is the progression of a somatic sensory system over time from its formation to the mature structure. Somatic sensory system is the sensory system for the sense of touch and pain. http://purl.obolibrary.org/obo/UBERON_0006851 renal cortex peritubular capillary http://purl.obolibrary.org/obo/UBERON_0005272 peritubular capillary A peritubular capillary that is part of a cortex of kidney. http://purl.obolibrary.org/obo/GO_0160048 craniofacial suture closure http://purl.obolibrary.org/obo/GO_0060349 bone morphogenesis The process of fusing together the edges of a craniofacial suture. http://purl.obolibrary.org/obo/UBERON_0006853 renal cortex tubule http://purl.obolibrary.org/obo/UBERON_0007685 region of nephron tubule A region of nephron tubule that is part of a cortex of kidney. http://purl.obolibrary.org/obo/CL_0004218 H2 horizontal cell http://purl.obolibrary.org/obo/CL_0000745 retina horizontal cell A horizontal cell with a small cell body, thin dendrites, and small dendritic arbor. http://purl.obolibrary.org/obo/UBERON_0006855 muscular coat of ureter http://purl.obolibrary.org/obo/UBERON_0006660 muscular coat A muscular coat that is part of a ureter. http://purl.obolibrary.org/obo/CL_0003008 G5 retinal ganglion cell http://purl.obolibrary.org/obo/CL_0000740 retinal ganglion cell A mono-stratified retinal ganglion cell that has a medium dendritic field and a medium dendritic arbor with post sympatic terminals in sublaminar layer S2. http://purl.obolibrary.org/obo/UBERON_0006858 adrenal/interrenal gland http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure This gland can either be a discrete structure located bilaterally above each kidney, or a cluster of cells in the head kidney that perform the functions of the adrenal gland. In either case, this organ consists of two cells types, aminergic chromaffin cells and steroidogenic cortical cells[GO]. http://purl.obolibrary.org/obo/CL_4023039 amygdala excitatory neuron http://purl.obolibrary.org/obo/CL_0012001 neuron of the forebrain Any neuron that has its soma located in some amygdala and is capable of some glutamate secretion, neurotransmission. http://purl.obolibrary.org/obo/UBERON_0006861 diaphysis proper http://purl.obolibrary.org/obo/UBERON_0005055 zone of long bone Subdivision of long bone which forms the part of the bone between two metaphyses. Note that the diaphysis includes the metaphyses, but the diaphysis proper excludes these. http://purl.obolibrary.org/obo/CL_4033013 suprabasal keratinocyte http://purl.obolibrary.org/obo/CL_4052061 epidermal keratinocyte A keratinocyte that resides in the epidermal suprabasal layer and expresses differentiation markers, including keratin 1 and keratin 10, in both humans and mice. In human interfollicular epidermis, this cell retains proliferative capacity and possesses retrodifferentiation potential, acquiring basal-like properties during wound healing or basement membrane contact. http://purl.obolibrary.org/obo/UBERON_0006862 diaphysis of femur http://purl.obolibrary.org/obo/UBERON_0004769 diaphysis A diaphysis that is part of a femur[Automatically generated definition]. http://purl.obolibrary.org/obo/CL_0001066 erythroid progenitor cell, mammalian http://purl.obolibrary.org/obo/CL_0000038 erythroid progenitor cell A progenitor cell committed to the erythroid lineage. This cell is ter119-positive but lacks expression of other hematopoietic lineage markers (lin-negative). http://purl.obolibrary.org/obo/UBERON_0006863 proximal metaphysis of femur http://purl.obolibrary.org/obo/UBERON_0006865 metaphysis of femur A proximal metaphysis that is part of a femur. http://purl.obolibrary.org/obo/CL_0001070 beige adipocyte http://purl.obolibrary.org/obo/CL_0000136 adipocyte An adipocyte that is beige in color, thermogenic, and which differentiates in white fat tissue from a Myf5-negative progenitor. http://purl.obolibrary.org/obo/UBERON_0006865 metaphysis of femur http://purl.obolibrary.org/obo/UBERON_0001438 metaphysis A metaphysis that is part of a femur. http://purl.obolibrary.org/obo/CL_0008011 skeletal muscle satellite stem cell http://purl.obolibrary.org/obo/CL_0000594 skeletal muscle satellite cell A skeletal muscle satellite cell that divides by stem cell division. A proportion of this population undergoes symmetric stem cell division, producing two skeletal muscle satellite stem cells. The rest undergo asymmetric stem cell division - retaining their identity while budding off a daughter cell that differentiates into an adult skeletal muscle myoblast. http://purl.obolibrary.org/obo/UBERON_0006866 terminal part of digestive tract http://purl.obolibrary.org/obo/UBERON_0004921 subdivision of digestive tract The distalmost portion of the digestive tract, derived from the hindgut, and terminating with the anus. http://purl.obolibrary.org/obo/CL_0008012 quiescent skeletal muscle satellite cell http://purl.obolibrary.org/obo/CL_0000594 skeletal muscle satellite cell A skeletal muscle satellite cell that is mitotically quiescent. These cells are wedge shaped and have a large nuclear to cytoplasmic ratio with few organelles, a small nucleus and condensed interphase chromatin. Satellite cells typically remain in this state until activated following muscle damage. http://purl.obolibrary.org/obo/UBERON_0006868 seminal fluid secreting gland http://purl.obolibrary.org/obo/UBERON_0005399 male reproductive gland A gland that secretes a seminal fluid. http://purl.obolibrary.org/obo/CL_0008016 activated skeletal muscle satellite cell http://purl.obolibrary.org/obo/CL_0000594 skeletal muscle satellite cell A skeletal muscle satellite cell that has become mitotically active - typically following muscle damage. http://purl.obolibrary.org/obo/UBERON_0006871 embryonic footplate http://purl.obolibrary.org/obo/UBERON_0010130 embryonic autopod plate The distal elements of the developing limb of vertebrates that will give rise to the pes (foot). http://purl.obolibrary.org/obo/CL_0008017 adult skeletal muscle myoblast http://purl.obolibrary.org/obo/CL_0000515 skeletal muscle myoblast A skeletal muscle myoblast that is part of a skeletal mucle. These cells are formed following acivation and division of skeletal muscle satellite cells. They form a transient population that is lost when they fuse to form skeletal muscle fibers. http://purl.obolibrary.org/obo/UBERON_0006872 handplate apical ectodermal ridge http://purl.obolibrary.org/obo/UBERON_0004356 apical ectodermal ridge An apical ectodermal ridge that is part of a handplate. http://purl.obolibrary.org/obo/CL_0008018 somatic muscle myoblast http://purl.obolibrary.org/obo/CL_0000056 myoblast A myoblast that is commited to developing into a somatic muscle. http://purl.obolibrary.org/obo/UBERON_0006875 embryonic handplate http://purl.obolibrary.org/obo/UBERON_0010130 embryonic autopod plate The distal elements of the developing limb of vertebrates that will give rise to the manus (hand). http://purl.obolibrary.org/obo/CL_0008019 mesenchymal cell http://purl.obolibrary.org/obo/CL_0000219 motile cell A non-polarised cell precursor cell that is part of some mesenchyme, is associated with the cell matrix but is not connected to other cells and is capable of migration. http://purl.obolibrary.org/obo/UBERON_0006876 vasculature of organ http://purl.obolibrary.org/obo/UBERON_0002049 vasculature A vasculature that is part of a organ. http://purl.obolibrary.org/obo/CL_0008020 skeletal muscle satellite myogenic cell http://purl.obolibrary.org/obo/CL_0000594 skeletal muscle satellite cell A skeletal muscle satellite cell that undergoes symmetric division to produce two adult skeleltal muscle myoblasts. http://purl.obolibrary.org/obo/UBERON_0006877 vasculature of liver http://purl.obolibrary.org/obo/UBERON_0006876 vasculature of organ A vasculature that is part of a liver. http://purl.obolibrary.org/obo/CL_0008021 anterior lateral line ganglion neuron http://purl.obolibrary.org/obo/CL_2000031 lateral line ganglion neuron Any peripheral nervous system neuron that has its soma located in some anterior lateral line ganglion. http://purl.obolibrary.org/obo/UBERON_0006904 head mesenchyme from mesoderm http://purl.obolibrary.org/obo/UBERON_0005253 head mesenchyme A head mesenchyme that develops_from a mesoderm. http://purl.obolibrary.org/obo/CL_0008022 endocardial cushion cell http://purl.obolibrary.org/obo/CL_0002494 cardiocyte A mesenchymal cell of the endocardial cushion. These cells develop via an epithelial to mesenchymal transition when endocardial cells break cell-to-cell contacts and migrate into the cardiac jelly. Cells from this population form the heart septa and valves. http://purl.obolibrary.org/obo/UBERON_0006905 mandibular process mesenchyme http://purl.obolibrary.org/obo/UBERON_0005253 head mesenchyme Mesenchyme that is part of a mandibular prominence. http://purl.obolibrary.org/obo/CL_0008025 noradrenergic neuron http://purl.obolibrary.org/obo/CL_4033050 catecholaminergic neuron A neuron that release noradrenaline (noriphinephrine) as a neurotransmitter. http://purl.obolibrary.org/obo/UBERON_0006907 slow muscle tissue http://purl.obolibrary.org/obo/UBERON_0001134 skeletal muscle tissue The darker-colored muscle tissue of some mammals, composed of slow twitch muscle fibers. http://purl.obolibrary.org/obo/CL_0008026 open tracheal system tracheocyte http://purl.obolibrary.org/obo/CL_0000066 epithelial cell An epithelial cell that is part of the epithelium of a tracheal tube in an open tracheal system, such as that found in insects. http://purl.obolibrary.org/obo/UBERON_0006908 fast muscle tissue http://purl.obolibrary.org/obo/UBERON_0001134 skeletal muscle tissue The paler-colored muscle tissue of some mammals, composed of fast twitch muscle fibers. http://purl.obolibrary.org/obo/CL_0010000 keratinized cell of hair follicle http://purl.obolibrary.org/obo/CL_2000092 hair follicular keratinocyte A differentiating matrix keratinocyte that has initiated terminal differentiation and keratin synthesis. This cell undergoes a characteristic change while migrating upward from the hair follicle bulb, representing a committed progenitor cell destined to form the hair medulla, cortex and hair root sheath. http://purl.obolibrary.org/obo/UBERON_0006909 lumen of digestive tract http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space An anatomical space that surrounded_by a digestive tract. http://purl.obolibrary.org/obo/CL_0010015 coronet cell http://purl.obolibrary.org/obo/CL_0000066 epithelial cell A highly specialized cell type exclusive to and forming neuroepithelium of the Saccus vasculosus, covering the caudal diverticulum of the infundibular recess. http://purl.obolibrary.org/obo/UBERON_0006912 urinary bladder muscularis mucosa http://purl.obolibrary.org/obo/UBERON_0006676 muscularis mucosa A thin layer of smooth muscle within the bladder lamina propria. http://purl.obolibrary.org/obo/CL_0010016 collar cell http://purl.obolibrary.org/obo/CL_0000064 ciliated cell A cell with a flagellum surrounded by a collar of microvilli. The motion of the flagellum draws water past the microvilli, serving either a feeding or sensory function. Collar cells are found in multiple animals, including sponges, echinoderms, and cnidarians. They are also found outside animals in the choanoflagellates. Although collar cells are superficially similar, their cytoskeletal structure and functional biology are different in different groups of organisms. http://purl.obolibrary.org/obo/UBERON_0006913 lip epithelium http://purl.obolibrary.org/obo/UBERON_0003929 digestive tract epithelium An epithelium that is part of a lip. http://purl.obolibrary.org/obo/CL_0011007 paraxial cell http://purl.obolibrary.org/obo/CL_0000222 mesodermal cell A cell in the area of mesoderm in the neurulating embryo that flanks and forms simultaneously with the neural tube. The cells of this region give rise to somites. http://purl.obolibrary.org/obo/UBERON_0006914 squamous epithelium http://purl.obolibrary.org/obo/UBERON_0000483 epithelium An epithelium characterised by its most superficial layer consisting of squamous epithelial cells. http://purl.obolibrary.org/obo/CL_0011008 embryonic hemocyte http://purl.obolibrary.org/obo/CL_0000387 hemocyte (sensu Arthropoda) A hemocyte derived from the embryonic head mesoderm, which enters the hemolymph as a circulating cell. http://purl.obolibrary.org/obo/UBERON_0006915 stratified squamous epithelium http://purl.obolibrary.org/obo/UBERON_0006914 squamous epithelium Multilaminar epithelium which consists of more than one layer of squamous cells only one layer of which is in contact with a basement membrane. Examples: keratinized stratified squamous epithelium, epithelium of wall of esophagus.[FMA]. http://purl.obolibrary.org/obo/CL_0011009 embryonic plasmatocyte http://purl.obolibrary.org/obo/CL_0011008 embryonic hemocyte A plasmatocyte derived from the embryonic head mesoderm. http://purl.obolibrary.org/obo/UBERON_0006916 non-keratinized epithelium of tongue http://purl.obolibrary.org/obo/UBERON_0010304 non-keratinized stratified squamous epithelium A non-keratinized stratified squamous epithelium that is part of a tongue. http://purl.obolibrary.org/obo/CL_0011010 lateral mesodermal cell http://purl.obolibrary.org/obo/CL_0000222 mesodermal cell A cell derived from the mesoderm that is found at the periphery of the embryo. http://purl.obolibrary.org/obo/UBERON_0006919 tongue squamous epithelium http://purl.obolibrary.org/obo/UBERON_0006914 squamous epithelium A squamous epithelium that is part of a tongue. http://purl.obolibrary.org/obo/CL_0011011 intermediate mesodermal cell http://purl.obolibrary.org/obo/CL_0000222 mesodermal cell A cell derived from the mesoderm that is located between the paraxial mesoderm and the lateral plate. http://purl.obolibrary.org/obo/UBERON_0006920 esophagus squamous epithelium http://purl.obolibrary.org/obo/UBERON_0006914 squamous epithelium A squamous epithelium that is part of a esophagus. http://purl.obolibrary.org/obo/UBERON_0006921 stomach squamous epithelium http://purl.obolibrary.org/obo/UBERON_0001276 epithelium of stomach A squamous epithelium that is part of a stomach. http://purl.obolibrary.org/obo/CL_0011012 neural crest cell http://purl.obolibrary.org/obo/CL_0002321 embryonic cell (metazoa) A cell of the neural crest. Neural crest cells are multipotent. Premigratory neural crest cells are found at the neural plate boarder, some of which will undergo ectomesynchymal transition and delamination to form migratory neural crest cells. http://purl.obolibrary.org/obo/UBERON_0006922 cervix squamous epithelium http://purl.obolibrary.org/obo/UBERON_0010304 non-keratinized stratified squamous epithelium The squamous epithelium of the cervical portio is similar to that of the vagina, except that it is generally smooth and lacks rete pegs. Colposcopically, it appears featureless except for a fine network of vessels which is sometimes visible. The relative opacity and pale pink coloration of the squamous epithelium derives from its multi-layered histology and the location of its supporting vessels below the basement membrane. http://purl.obolibrary.org/obo/CL_0011114 segmented neutrophil of bone marrow http://purl.obolibrary.org/obo/CL_1001610 bone marrow hematopoietic cell A segmented neutrophilic cell of the bone marrow reserve pool that expresses CD11b (integrin alpha-M) and high levels of CD16 (low affinity immunoglobulin gamma Fc region receptor III) on its cell surface. http://purl.obolibrary.org/obo/UBERON_0006923 vagina squamous epithelium http://purl.obolibrary.org/obo/UBERON_0006915 stratified squamous epithelium A squamous epithelium that is part of a vagina. http://purl.obolibrary.org/obo/CL_2000007 articular chondrocyte of knee joint http://purl.obolibrary.org/obo/CL_1001607 articular chondrocyte Chondrocyte forming the hyaline cartilage found in the knee joint. http://purl.obolibrary.org/obo/UBERON_0006924 stomach glandular epithelium http://purl.obolibrary.org/obo/UBERON_0006929 glandular columnar epithelium A glandular epithelium that lines the stomach. The stomach's glandular epithelium is characterized by the presence of gastric glands. http://purl.obolibrary.org/obo/CL_2000008 microvascular endothelial cell http://purl.obolibrary.org/obo/CL_0000071 blood vessel endothelial cell Any blood vessel endothelial cell that is part of a microvascular endothelium. http://purl.obolibrary.org/obo/UBERON_0006925 digestive system gland http://purl.obolibrary.org/obo/UBERON_0013765 digestive system element Any gland that is part of the digestive system. http://purl.obolibrary.org/obo/CL_2000010 dermis blood vessel endothelial cell http://purl.obolibrary.org/obo/CL_0000071 blood vessel endothelial cell Any blood vessel endothelial cell that is part of a dermis. http://purl.obolibrary.org/obo/UBERON_0006929 glandular columnar epithelium http://purl.obolibrary.org/obo/UBERON_0006799 glandular epithelium Simple columnar epithelium that constitutes the secretory part of a gland. Examples: epithelium of stomach, luminal epithelium of lactiferous duct.[FMA]. http://purl.obolibrary.org/obo/CL_2000011 dermis lymphatic vessel endothelial cell http://purl.obolibrary.org/obo/CL_0002138 endothelial cell of lymphatic vessel Any endothelial cell of lymphatic vessel that is part of a dermis. http://purl.obolibrary.org/obo/UBERON_0006931 stomach glandular region mucosa http://purl.obolibrary.org/obo/UBERON_0001199 mucosa of stomach Stomach mucosa that is lined with glandular epithelium and part of a stomach glandular region. http://purl.obolibrary.org/obo/CL_2000012 fibroblast of pedal digit skin http://purl.obolibrary.org/obo/CL_0002620 skin fibroblast Any skin fibroblast that is part of a pedal digit skin. http://purl.obolibrary.org/obo/UBERON_0006932 vestibular epithelium http://purl.obolibrary.org/obo/UBERON_0006937 inner ear epithelium An epithelium that is part of a vestibular labyrinth. http://purl.obolibrary.org/obo/CL_2000013 fibroblast of skin of abdomen http://purl.obolibrary.org/obo/CL_0002620 skin fibroblast Any skin fibroblast that is part of a skin of abdomen. http://purl.obolibrary.org/obo/UBERON_0006934 sensory epithelium http://purl.obolibrary.org/obo/UBERON_0000488 atypical epithelium Simple columnar epithelium made up of cells specialized to serve as sensory cells for the reception of external stimuli, as the sensory cells of the cochlea, vestibule, nasal mucosa, and tongue. http://purl.obolibrary.org/obo/CL_2000014 fibroblast of upper leg skin http://purl.obolibrary.org/obo/CL_0002620 skin fibroblast Any skin fibroblast that is part of a upper leg skin. http://purl.obolibrary.org/obo/UBERON_0006935 crista ampullaris neuroepithelium http://purl.obolibrary.org/obo/UBERON_0006932 vestibular epithelium An epithelium that is part of a crista ampullaris. http://purl.obolibrary.org/obo/CL_2000015 fibroblast of arm http://purl.obolibrary.org/obo/CL_0002620 skin fibroblast Any skin fibroblast that is part of a arm. http://purl.obolibrary.org/obo/UBERON_0006936 thymus subcapsular epithelium http://purl.obolibrary.org/obo/UBERON_0003846 thymus epithelium The epithelial cells lining the capsule and trabeculae of the thymus. http://purl.obolibrary.org/obo/CL_2000016 lung microvascular endothelial cell http://purl.obolibrary.org/obo/CL_2000008 microvascular endothelial cell Any lung endothelial cell that is part of a microvascular endothelium. http://purl.obolibrary.org/obo/UBERON_0006937 inner ear epithelium http://purl.obolibrary.org/obo/UBERON_0015807 ear epithelium The epithelial cell layer containing the sensory hair cells and their associated sensory nerve terminals. http://purl.obolibrary.org/obo/CL_2000017 fibroblast of peridontal ligament http://purl.obolibrary.org/obo/CL_0002556 fibroblast of periodontium Any fibroblast that is part of a periodontal ligament. http://purl.obolibrary.org/obo/UBERON_0006938 pinna surface epithelium http://purl.obolibrary.org/obo/UBERON_0015814 outer ear epithelium An epithelium that is part of a pinna. http://purl.obolibrary.org/obo/CL_2000018 endothelial cell of coronary artery http://purl.obolibrary.org/obo/CL_1000413 endothelial cell of artery Any endothelial cell of artery that is part of a coronary artery. http://purl.obolibrary.org/obo/UBERON_0006946 efferent duct http://purl.obolibrary.org/obo/UBERON_0005904 duct of male reproductive system The efferent ducts (or efferent ductules or ductuli efferentes) connect the rete testis with the initial section of the epididymis. The ductuli are unilaminar and composed of columnar ciliated and non-ciliated (absorptive) cells. The ciliated cells serve to stir the luminal fluids, possibly to help ensure homogeneous absorption of water from the fluid produced by the testis, which results in an increase in the concentration of luminal sperm. The epithelium is surrounded by a band of smooth muscle that helps to propel the sperm toward the epididymis. http://purl.obolibrary.org/obo/CL_2000019 compound eye photoreceptor cell http://purl.obolibrary.org/obo/CL_0000287 eye photoreceptor cell Any photoreceptor cell that is part of a compound eye. http://purl.obolibrary.org/obo/UBERON_0006947 male genital duct http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure A duct or series of ducts that transports sperm from the gonad. In mammals this is from the seminiferous tubules through rete testis, vas efferentia, epididymis, vas deferens, ejeculatory duct to the urethra. http://purl.obolibrary.org/obo/CL_2000020 inner cell mass cell http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell Any native cell that is part of a inner cell mass. http://purl.obolibrary.org/obo/UBERON_0006948 efferent duct epithelium http://purl.obolibrary.org/obo/UBERON_0034969 epithelial layer of duct An epithelium that is part of a efferent duct. http://purl.obolibrary.org/obo/CL_2000021 sebaceous gland cell http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell Any native cell that is part of a sebaceous gland. http://purl.obolibrary.org/obo/UBERON_0006953 ejaculatory duct epithelium http://purl.obolibrary.org/obo/UBERON_0034969 epithelial layer of duct The ejaculatory duct epithelium is composed of cuboidal to columnar cells between or through which project the terminal parts of the ducts of the unicellular prostate glands. http://purl.obolibrary.org/obo/CL_2000022 cardiac septum cell http://purl.obolibrary.org/obo/CL_0002494 cardiocyte Any native cell that is part of a cardiac septum. http://purl.obolibrary.org/obo/UBERON_0006954 mammary gland myoepithelium http://purl.obolibrary.org/obo/UBERON_0003244 epithelium of mammary gland The outer cell layer of the mammary gland epithelium bilayer which is located basal to the luminal (secretory) cells and adjacent to the basement membrane. http://purl.obolibrary.org/obo/CL_2000023 spinal cord ventral column interneuron http://purl.obolibrary.org/obo/CL_0005000 spinal cord interneuron Any interneuron that is part of a spinal cord ventral column. http://purl.obolibrary.org/obo/UBERON_0006955 uterine epithelium http://purl.obolibrary.org/obo/UBERON_0004804 oviduct epithelium An epithelium that is part of a uterus. http://purl.obolibrary.org/obo/CL_2000024 spinal cord medial motor column neuron http://purl.obolibrary.org/obo/CL_2000029 central nervous system neuron Any neuron that is part of a spinal cord medial motor column. http://purl.obolibrary.org/obo/UBERON_0006957 submandibular gland primordium epithelium http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue An epithelium that is part of a submandibular gland primordium. http://purl.obolibrary.org/obo/CL_2000025 spinal cord oligodendrocyte http://purl.obolibrary.org/obo/CL_0000128 oligodendrocyte Any oligodendrocyte that is part of a spinal cord. http://purl.obolibrary.org/obo/UBERON_0006960 ovary stroma http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure The stroma of the ovary is a peculiar soft tissue, abundantly supplied with blood vessels, consisting for the most part of spindle-shaped cells with a small amount of ordinary connective tissue. These cells have been regarded by some anatomists as unstriped muscle cells, which, indeed, they most resemble; by others as connective-tissue cells. On the surface of the organ this tissue is much condensed, and forms a layer composed of short connective-tissue fibers, with fusiform cells between them. The stroma of the ovary may contain interstitial cells resembling those of the testis. http://purl.obolibrary.org/obo/CL_2000027 cerebellar basket cell http://purl.obolibrary.org/obo/CL_0000118 basket cell A GABAergic inhibitory interneuron located in the molecular layer of the cerebellar cortex. It projects axons that form specialized synaptic structures around Purkinje cells, including pericellular baskets, which wrap around the Purkinje cell soma, and the pinceau: a brush-like terminal that contacts the initial segment of the Purkinje cell axon. The basket cell modulates Purkinje cell activity through both chemical (GABAergic) and non-synaptic (ephaptic) mechanisms. It is arranged in sagittal rows that align with Purkinje cell zones, contributing to the cerebellum's modular and topographically organized architecture. It plays an essential role in regulating motor coordination and potentially cognitive functions. http://purl.obolibrary.org/obo/UBERON_0006964 pars distalis of adenohypophysis http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure The distal part of adenohypophysis: the part that makes up the main body of the gland. http://purl.obolibrary.org/obo/CL_2000028 cerebellum glutamatergic neuron http://purl.obolibrary.org/obo/CL_1001611 cerebellar neuron Any glutamatergic neuron that is part of a cerebellum. http://purl.obolibrary.org/obo/UBERON_0006965 vascular cord http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure The vascular cord is the primordial vasculature that will develop into blood vessels by the process of tubulogenesis[GO]. The vascular cord is composed of angioblast or vascular endothelial cells in a solid linear mass called a cord. The cord then undergoes tubulogenesis to form the lumen of the vessels[ZFA]. http://purl.obolibrary.org/obo/CL_2000029 central nervous system neuron http://purl.obolibrary.org/obo/CL_0000540 neuron Any neuron that is part of a central nervous system. http://purl.obolibrary.org/obo/UBERON_0006966 coronary capillary http://purl.obolibrary.org/obo/UBERON_0003498 heart blood vessel A capillary that is part of the coronary system. http://purl.obolibrary.org/obo/CL_2000030 hypothalamus cell http://purl.obolibrary.org/obo/CL_0002319 neural cell Any native cell that is part of a hypothalamus. http://purl.obolibrary.org/obo/UBERON_0006984 anatomical surface http://purl.obolibrary.org/obo/UBERON_0010199 bona-fide anatomical boundary A two dimensional anatomical structure that is the boundary between an anatomical structure and an anatomical substance, an anatomical space or the organism's environment. Examples include the surface of your skin, the surface of the lining of your gut; the surface of the endothelium of you aorta that is in contact with blood.n. http://purl.obolibrary.org/obo/CL_2000031 lateral line ganglion neuron http://purl.obolibrary.org/obo/CL_2000032 peripheral nervous system neuron Any neuron that is part of a lateral line ganglion. http://purl.obolibrary.org/obo/UBERON_0007005 cardiogenic splanchnic mesoderm http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue The splanchnic mesoderm in the cardiogenic region where the heart develops; it gives rise to endocardial heart tubes that fuse to form the primordial cardiac tube, the heart primordium[web]. Two migratory heart primordia that move ventrally during the course of neurulation, and then fuse[XAO]. http://purl.obolibrary.org/obo/CL_2000032 peripheral nervous system neuron http://purl.obolibrary.org/obo/CL_0000540 neuron A neuron that is part of a peripheral nervous system. http://purl.obolibrary.org/obo/UBERON_0007010 cleaving embryo http://purl.obolibrary.org/obo/UBERON_0000922 embryo Organism at the cleavage stage. http://purl.obolibrary.org/obo/CL_2000033 limb basal cell of epidermis http://purl.obolibrary.org/obo/CL_0002187 basal cell of epidermis Any basal cell of epidermis that is part of a limb. http://purl.obolibrary.org/obo/UBERON_0007021 sexually immature organism http://purl.obolibrary.org/obo/UBERON_0000468 multicellular organism A multicellular organism that is at the juvenile stage. http://purl.obolibrary.org/obo/CL_2000034 anterior lateral line neuromast hair cell http://purl.obolibrary.org/obo/CL_0000856 neuromast hair cell Any neuromast hair cell that is part of a anterior lateral line. http://purl.obolibrary.org/obo/UBERON_0007023 adult organism http://purl.obolibrary.org/obo/UBERON_0000468 multicellular organism A multicellular organism that existence_ends_with a post-juvenile adult stage and existence_starts_with a post-juvenile adult stage. http://purl.obolibrary.org/obo/CL_2000035 anterior lateral line neuromast mantle cell http://purl.obolibrary.org/obo/CL_0000851 neuromast mantle cell Any neuromast mantle cell that is part of an anterior lateral line. http://purl.obolibrary.org/obo/UBERON_0007098 mandibular neural crest http://purl.obolibrary.org/obo/UBERON_0003099 cranial neural crest Cranial neural crest that migrates into the mandibular arch. http://purl.obolibrary.org/obo/UBERON_0007099 hyoid neural crest http://purl.obolibrary.org/obo/UBERON_0003099 cranial neural crest Cranial neural crest that migrates into the hyoid arch. http://purl.obolibrary.org/obo/CL_2000036 anterior lateral line neuromast supporting cell http://purl.obolibrary.org/obo/CL_0000852 neuromast supporting cell Any neuromast support cell that is part of a anterior lateral line. http://purl.obolibrary.org/obo/UBERON_0007100 primary circulatory organ http://purl.obolibrary.org/obo/UBERON_0015228 circulatory organ A hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood or analogs[GO,modified]. http://purl.obolibrary.org/obo/CL_2000037 posterior lateral line neuromast hair cell http://purl.obolibrary.org/obo/CL_0000856 neuromast hair cell Any neuromast hair cell that is part of a posterior lateral line. http://purl.obolibrary.org/obo/UBERON_0007106 chorionic villus http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure One of the minute vascular projections of the fetal chorion that combines with maternal uterine tissue to form the placenta. http://purl.obolibrary.org/obo/CL_2000038 posterior lateral line neuromast mantle cell http://purl.obolibrary.org/obo/CL_0000851 neuromast mantle cell Any neuromast mantle cell that is part of a posterior lateral line. http://purl.obolibrary.org/obo/UBERON_0007119 neck of femur http://purl.obolibrary.org/obo/UBERON_0018664 neck of bone element The femur neck or neck of the femur is a flattened pyramidal process of bone, connecting the femoral head with the femoral shaft, and forming with the latter a wide angle opening medialward. http://purl.obolibrary.org/obo/CL_2000039 posterior lateral line neuromast supporting cell http://purl.obolibrary.org/obo/CL_0000852 neuromast supporting cell Any neuromast support cell that is part of a posterior lateral line. http://purl.obolibrary.org/obo/UBERON_0007122 pharyngeal pouch 1 http://purl.obolibrary.org/obo/UBERON_0004117 pharyngeal pouch A pharyngeal pouch that is between pharyngeal arches 1 and 2. http://purl.obolibrary.org/obo/CL_2000040 bladder microvascular endothelial cell http://purl.obolibrary.org/obo/CL_2000008 microvascular endothelial cell Any microvascular endothelial cell that is part of a urinary bladder. http://purl.obolibrary.org/obo/UBERON_0007123 pharyngeal pouch 2 http://purl.obolibrary.org/obo/UBERON_0004117 pharyngeal pouch A pharyngeal puch that is between the pharyngeal arches 2 and 3. http://purl.obolibrary.org/obo/CL_2000041 dermis microvascular lymphatic vessel endothelial cell http://purl.obolibrary.org/obo/CL_0011030 dermal microvascular endothelial cell Any dermis lymphatic vessel endothelial cell that is part of a microvascular endothelium. http://purl.obolibrary.org/obo/UBERON_0007124 pharyngeal pouch 3 http://purl.obolibrary.org/obo/UBERON_0004117 pharyngeal pouch A pharyngeal pouch that between pharyngeal arches 3 and 4. http://purl.obolibrary.org/obo/CL_2000042 embryonic fibroblast http://purl.obolibrary.org/obo/CL_0000057 fibroblast Any fibroblast that is part of a embryo. http://purl.obolibrary.org/obo/UBERON_0007125 pharyngeal pouch 4 http://purl.obolibrary.org/obo/UBERON_0004117 pharyngeal pouch A pharyngeal pouch between pharyngeal arch 4 and arch 5 or 6 (a fifth arch never establishes in amniotes). http://purl.obolibrary.org/obo/CL_2000043 brain pericyte http://purl.obolibrary.org/obo/CL_0002575 central nervous system pericyte Any pericyte cell that is part of a brain. http://purl.obolibrary.org/obo/UBERON_0007128 glomeral mesenchyme http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure Portion of tissue that consists of the precursors of the pronephric glomus or glomerulus; derived from the medial portion of the pronephric intermediate mesoderm. http://purl.obolibrary.org/obo/CL_2000044 brain microvascular endothelial cell http://purl.obolibrary.org/obo/CL_2000008 microvascular endothelial cell Any microvascular endothelial cell that is part of a brain. http://purl.obolibrary.org/obo/CL_2000045 foreskin melanocyte http://purl.obolibrary.org/obo/CL_1000458 melanocyte of skin Any melanocyte of skin that is part of a skin of prepuce of penis. http://purl.obolibrary.org/obo/UBERON_0007134 trunk ganglion http://purl.obolibrary.org/obo/UBERON_0000045 ganglion Ganglion which is located in the trunk. http://purl.obolibrary.org/obo/CL_2000046 ventricular cardiac muscle cell http://purl.obolibrary.org/obo/CL_0000746 cardiac muscle cell Any cardiac muscle cell that is part of a cardiac ventricle. http://purl.obolibrary.org/obo/UBERON_0007135 neural keel http://purl.obolibrary.org/obo/UBERON_0016879 future central nervous system An intermediate stage (between the neural plate and neural rod) during the early segmentation period in the morphogenesis of the central nervous system primordium; the keel is roughly triangular shaped in cross section. http://purl.obolibrary.org/obo/CL_2000047 brainstem motor neuron http://purl.obolibrary.org/obo/CL_2000029 central nervous system neuron Any motor neuron that is part of a brainstem. http://purl.obolibrary.org/obo/UBERON_0007142 left internal carotid artery http://purl.obolibrary.org/obo/UBERON_0001532 internal carotid artery An internal carotid artery that branching_part_of a left common carotid artery plus branches. http://purl.obolibrary.org/obo/CL_2000048 anterior horn motor neuron http://purl.obolibrary.org/obo/CL_0008039 lower motor neuron A lower motor neuron whose soma is located in the anterior horn. Anterior horn motor neurons project from the anterior portion of the grey matter in the spinal cord to some skeletal muscles. http://purl.obolibrary.org/obo/UBERON_0007143 right internal carotid artery http://purl.obolibrary.org/obo/UBERON_0001532 internal carotid artery An internal carotid artery that branching_part_of a right common carotid artery plus branches. http://purl.obolibrary.org/obo/CL_2000049 primary motor cortex pyramidal cell http://purl.obolibrary.org/obo/CL_4023111 cerebral cortex pyramidal neuron Any pyramidal cell that is part of a primary motor cortex. http://purl.obolibrary.org/obo/UBERON_0007144 embryonic post-anal tail http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure An embryonic structure that will either develop into a post-anal tail or recede into a vestigial remnant of the tail. http://purl.obolibrary.org/obo/CL_2000051 splenic fibroblast http://purl.obolibrary.org/obo/CL_0000057 fibroblast Any fibroblast that is part of a spleen. http://purl.obolibrary.org/obo/UBERON_0007147 lumen of midgut http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space An anatomical cavity that surrounded_by a midgut. http://purl.obolibrary.org/obo/CL_2000052 umbilical artery endothelial cell http://purl.obolibrary.org/obo/CL_1000413 endothelial cell of artery Any endothelial cell of artery that is part of a umbilical cord. http://purl.obolibrary.org/obo/UBERON_0007148 lumen of hindgut http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space An anatomical cavity that surrounded_by a hindgut. http://purl.obolibrary.org/obo/CL_2000053 splenic endothelial cell http://purl.obolibrary.org/obo/CL_0000115 endothelial cell Any endothelial cell that is part of a spleen. http://purl.obolibrary.org/obo/UBERON_0007158 lumen of anal canal http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space An anatomical cavity that surrounded_by a anal canal. http://purl.obolibrary.org/obo/CL_2000054 hepatic pit cell http://purl.obolibrary.org/obo/CL_4047101 liver-resident natural killer cell A large, granular, liver specific natural killer cell that adheres to the endothelial cells of the hepatic sinusoid. http://purl.obolibrary.org/obo/UBERON_0007159 lumen of colon http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space An anatomical cavity that surrounded_by a colon. http://purl.obolibrary.org/obo/CL_2000055 liver dendritic cell http://purl.obolibrary.org/obo/CL_0000451 dendritic cell Any dendritic cell that is part of a liver. http://purl.obolibrary.org/obo/UBERON_0007160 inferior petrosal sinus http://purl.obolibrary.org/obo/UBERON_0017635 paired venous dural sinus The inferior petrosal sinus, within the human head, is an area beneath the brain, which allows blood veins to span the area, from the center of the head downward. It drains from the cavernous sinus (beneath the brain) to the sigmoid sinuses above the internal jugular vein. http://purl.obolibrary.org/obo/CL_2000056 Meynert cell http://purl.obolibrary.org/obo/CL_2000049 primary motor cortex pyramidal cell Any pyramidal cell that is part of a regional part of cerebral cortex. http://purl.obolibrary.org/obo/UBERON_0007173 lateral border of scapula http://purl.obolibrary.org/obo/UBERON_0007171 border of scapula The lateral border (or axillary border, or margin) is the thickest of the three borders of the scapula. It begins above at the lower margin of the glenoid cavity, and inclines obliquely downward and backward to the inferior angle. Immediately below the glenoid cavity is a rough impression, the infraglenoid tuberosity, about 2.5 cm. in length, which gives origin to the long head of the Triceps brachii; in front of this is a longitudinal groove, which extends as far as the lower third of this border, and affords origin to part of the Subscapularis. The inferior third is thin and sharp, and serves for the attachment of a few fibers of the Teres major behind, and of the Subscapularis in front. http://purl.obolibrary.org/obo/CL_2000057 femoral osteoblast http://purl.obolibrary.org/obo/CL_0001035 bone cell Any osteoblast that is part of a femur. http://purl.obolibrary.org/obo/UBERON_0007174 medial border of scapula http://purl.obolibrary.org/obo/UBERON_0007171 border of scapula The medial border of the scapula (vertebral border, medial margin) is the longest of the three borders, and extends from the medial to the inferior angle. It is arched, intermediate in thickness between the superior and the axillary borders, and the portion of it above the spine forms an obtuse angle with the part below. This border presents an anterior and a posterior lip, and an intermediate narrow area. The anterior lip affords attachment to the Serratus anterior; the posterior lip, to the Supraspinatus above the spine, the Infraspinatus below; the area between the two lips, to the Levator scapulC& above the triangular surface at the commencement of the spine, to the Rhomboideus minor on the edge of that surface, and to the Rhomboideus major below it; this last is attached by means of a fibrous arch, connected above to the lower part of the triangular surface at the base of the spine, and below to the lower part of the border. http://purl.obolibrary.org/obo/CL_2000058 calvarial osteoblast http://purl.obolibrary.org/obo/CL_0000062 osteoblast Any osteoblast that is part of a skull. http://purl.obolibrary.org/obo/UBERON_0007175 inferior angle of scapula http://purl.obolibrary.org/obo/UBERON_0007172 angle of scapula An angle of the scapula formed by the union of the vertebral and axillary borders; its dorsal surface affords attachment to the Teres major and frequently to a few fibers of the Latissimus dorsi.[WP,unvetted]. http://purl.obolibrary.org/obo/CL_2000059 prostate gland microvascular endothelial cell http://purl.obolibrary.org/obo/CL_2000008 microvascular endothelial cell Any microvascular endothelial cell that is part of a prostate gland. http://purl.obolibrary.org/obo/UBERON_0007177 lamina propria of mucosa of colon http://purl.obolibrary.org/obo/UBERON_0011189 lamina propria of large intestine A lamina propria that is part of a colonic mucosa. http://purl.obolibrary.org/obo/CL_2000060 placental villous trophoblast http://purl.obolibrary.org/obo/CL_0000351 trophoblast cell A trophoblast of placental villi. These cells fuse to form synctial trophoplast - the placental side of the interface between the placenta and maternal blood sinusoids in the decidua. http://purl.obolibrary.org/obo/UBERON_0007178 muscularis mucosae of colon http://purl.obolibrary.org/obo/UBERON_0001239 muscularis mucosae of large intestine A muscularis mucosa that is part of a colonic mucosa. http://purl.obolibrary.org/obo/CL_2000061 placental amniotic mesenchymal stromal cell http://purl.obolibrary.org/obo/CL_0000134 mesenchymal stem cell Any mesenchymal stem cell that is part of a placenta. http://purl.obolibrary.org/obo/UBERON_0007181 serosa of infundibulum of uterine tube http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure A serous membrane that is part of a uterine tube infundibulum. http://purl.obolibrary.org/obo/CL_2000062 placental villus capillary endothelial cell http://purl.obolibrary.org/obo/CL_0009092 endothelial cell of placenta Any capillary endothelial cell that is part of a placenta. http://purl.obolibrary.org/obo/UBERON_0007182 muscle layer of infundibulum of uterine tube http://purl.obolibrary.org/obo/UBERON_0006660 muscular coat A muscle layer that is part of a uterine tube infundibulum. http://purl.obolibrary.org/obo/CL_2000063 ovarian fibroblast http://purl.obolibrary.org/obo/CL_0002132 stromal cell of ovary Any fibroblast that is part of a female gonad. http://purl.obolibrary.org/obo/UBERON_0007188 mesothelium of serous pericardium http://purl.obolibrary.org/obo/UBERON_0003388 mesothelium of pericardial cavity A mesothelium that is part of a serous pericardium. http://purl.obolibrary.org/obo/CL_2000064 ovarian surface epithelial cell http://purl.obolibrary.org/obo/CL_0002078 meso-epithelial cell A meso-epithelial cell of the ovarian surface epithelium, varying in shape from flat to cuboidal to pseudostratified columnar. This cell plays a crucial role in ovulation by producing proteolytic enzymes in response to gonadotropins, facilitating follicle rupture through tissue breakdown and TNF-alpha signaling. Additionally, this cell contributes to post-ovulatory wound repair (Morris et al., 2022) and exhibits stem cell-like properties (Flesken-Nikitin et al., 2013; Wang et al., 2019). http://purl.obolibrary.org/obo/UBERON_0007195 stroma of bone marrow http://purl.obolibrary.org/obo/UBERON_0003891 stroma The stroma of the bone marrow is all tissue not directly involved in the primary function of hematopoiesis. The yellow bone marrow belongs here, and makes the majority of the bone marrow stroma, in addition to stromal cells located in the red bone marrow. Yellow bone marrow is found in the Medullary cavity. Still, the stroma is indirectly involved in hematopoiesis, since it provides the hematopoietic microenvironment that facilitates hematopoiesis by the parenchymal cells. For instance, they generate colony stimulating factors, affecting hematopoiesis. http://purl.obolibrary.org/obo/CL_2000065 ovarian microvascular endothelial cell http://purl.obolibrary.org/obo/CL_2000008 microvascular endothelial cell Any microvascular endothelial cell that is part of a female urethra. http://purl.obolibrary.org/obo/UBERON_0007196 tracheobronchial tree http://purl.obolibrary.org/obo/UBERON_0000062 organ The structure from the trachea, bronchi, and bronchioles that forms the airways that supply air to the lungs. The lining of the tracheobronchial tree consists of ciliated columnar epithelial cells. http://purl.obolibrary.org/obo/CL_2000066 cardiac ventricle fibroblast http://purl.obolibrary.org/obo/CL_0002548 fibroblast of cardiac tissue Any fibroblast that is part of a cardiac ventricle. http://purl.obolibrary.org/obo/UBERON_0007197 hermaphroditic organism http://purl.obolibrary.org/obo/UBERON_0000468 multicellular organism Multicellular organism that can produce both male and female gametes. http://purl.obolibrary.org/obo/CL_2000067 cardiac atrium fibroblast http://purl.obolibrary.org/obo/CL_0002548 fibroblast of cardiac tissue Any fibroblast that is part of a cardiac atrium. http://purl.obolibrary.org/obo/UBERON_0007198 hermaphrodite anatomical structure http://purl.obolibrary.org/obo/UBERON_0014402 sex-specific anatomical structure An anatomical structure present only in hermaphrodites. http://purl.obolibrary.org/obo/CL_2000068 pericardium fibroblast http://purl.obolibrary.org/obo/CL_0000057 fibroblast Any fibroblast that is part of a pericardium. http://purl.obolibrary.org/obo/UBERON_0007204 brachiocephalic vasculature http://purl.obolibrary.org/obo/UBERON_0002049 vasculature The vasculature consisting of brachiocephalic arteries and veins. http://purl.obolibrary.org/obo/CL_2000069 gallbladder fibroblast http://purl.obolibrary.org/obo/CL_0000057 fibroblast Any fibroblast that is part of a gallbladder. http://purl.obolibrary.org/obo/UBERON_0007213 mesenchyme derived from head neural crest http://purl.obolibrary.org/obo/UBERON_0005253 head mesenchyme Mesenchyme that develops_from a cranial neural crest. http://purl.obolibrary.org/obo/CL_2000070 optic choroid fibroblast http://purl.obolibrary.org/obo/CL_0000348 choroidal cell of the eye Any fibroblast that is part of a optic choroid. http://purl.obolibrary.org/obo/UBERON_0007214 mesenchyme derived from trunk neural crest http://purl.obolibrary.org/obo/UBERON_0005256 trunk mesenchyme Mesenchyme that develops_from a trunk neural crest. http://purl.obolibrary.org/obo/CL_2000071 mammary microvascular endothelial cell http://purl.obolibrary.org/obo/CL_2000008 microvascular endothelial cell Any microvascular endothelial cell that is part of a breast. http://purl.obolibrary.org/obo/UBERON_0007220 late embryonic stage http://purl.obolibrary.org/obo/UBERON_0000105 life cycle stage An embryo stage that covers late steps of the embryogenesis with a fully formed embryo still developing before birth or egg hatching. http://purl.obolibrary.org/obo/CL_2000072 adipose microvascular endothelial cell http://purl.obolibrary.org/obo/CL_2000008 microvascular endothelial cell Any microvascular endothelial cell that is part of a adipose tissue. http://purl.obolibrary.org/obo/UBERON_0007221 neonate stage http://purl.obolibrary.org/obo/UBERON_0000105 life cycle stage Of or pertaining to the period of time immediately following birth, or to the newborn. http://purl.obolibrary.org/obo/CL_2000073 migratory cardiac neural crest cell http://purl.obolibrary.org/obo/CL_0000333 migratory neural crest cell Any migratory neural crest cell that is part of a cardiac neural crest. http://purl.obolibrary.org/obo/UBERON_0007223 osseus cochlea http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure The osseous cochlea is the bony foundation that forms the small shell arrangement for the cochlear nerve. http://purl.obolibrary.org/obo/CL_2000074 splenocyte http://purl.obolibrary.org/obo/CL_0000738 leukocyte Any leukocyte that is part of a spleen. http://purl.obolibrary.org/obo/UBERON_0007228 vestibular nucleus http://purl.obolibrary.org/obo/UBERON_0007635 nucleus of medulla oblongata A cranial nucleus for the vestibular nerve. [WP,unvetted]. http://purl.obolibrary.org/obo/CL_2000075 anterior visceral endoderm cell http://purl.obolibrary.org/obo/CL_0000223 endodermal cell Any endodermal cell that is part of a anterior visceral endoderm. http://purl.obolibrary.org/obo/UBERON_0007239 tunica media of artery http://purl.obolibrary.org/obo/UBERON_0002522 tunica media A tunica media that is part of a artery. http://purl.obolibrary.org/obo/CL_2000076 hindlimb stylopod vein endothelial cell http://purl.obolibrary.org/obo/CL_0002543 vein endothelial cell Any vein endothelial cell that is part of a hindlimb stylopod. http://purl.obolibrary.org/obo/UBERON_0007240 tunica adventitia of artery http://purl.obolibrary.org/obo/UBERON_0005734 tunica adventitia of blood vessel A tunica adventitia that is part of a artery. http://purl.obolibrary.org/obo/CL_2000077 skeletal muscle tissue of pectoralis major striated muscle cell http://purl.obolibrary.org/obo/CL_0000737 striated muscle cell Any striated muscle cell that is part of a skeletal muscle tissue of pectoralis major. http://purl.obolibrary.org/obo/UBERON_0007241 tunica adventitia of vein http://purl.obolibrary.org/obo/UBERON_0005734 tunica adventitia of blood vessel A tunica adventitia that is part of a vein. http://purl.obolibrary.org/obo/CL_2000078 placental pericyte http://purl.obolibrary.org/obo/CL_0000669 pericyte Any pericyte cell that is part of a placenta. http://purl.obolibrary.org/obo/UBERON_0007242 tunica intima of vein http://purl.obolibrary.org/obo/UBERON_0004797 blood vessel layer A tunica intima that is part of a vein. http://purl.obolibrary.org/obo/CL_2000079 mesenchymal stem cell of femoral bone marrow http://purl.obolibrary.org/obo/CL_0002540 mesenchymal stem cell of the bone marrow Any mesenchymal stem cell of the bone marrow that is part of a femur. http://purl.obolibrary.org/obo/UBERON_0007243 tunica media of vein http://purl.obolibrary.org/obo/UBERON_0002522 tunica media A tunica media that is part of a vein. http://purl.obolibrary.org/obo/CL_2000080 mesenchymal stem cell of abdominal adipose tissue http://purl.obolibrary.org/obo/CL_0002570 mesenchymal stem cell of adipose tissue Any mesenchymal stem cell of adipose tissue that is part of an abdomen. http://purl.obolibrary.org/obo/UBERON_0007245 nuclear complex of neuraxis http://purl.obolibrary.org/obo/UBERON_0002020 gray matter Gray matter of the central nervous system which is a collection of clustered nuclei. http://purl.obolibrary.org/obo/CL_2000081 melanocyte of skin of face http://purl.obolibrary.org/obo/CL_1000458 melanocyte of skin Any melanocyte of skin that is part of a skin of face. http://purl.obolibrary.org/obo/UBERON_0007247 nucleus of superior olivary complex http://purl.obolibrary.org/obo/UBERON_0009662 hindbrain nucleus Any of the nuclei that comprise the superior olivary complex (superior olive). This includes both the primary nuclei such as the lateral and medial nuclei, as well as periolivary nuclei. http://purl.obolibrary.org/obo/CL_2000083 hair follicle dermal papilla cell of scalp http://purl.obolibrary.org/obo/CL_0000346 hair follicle dermal papilla cell Any hair follicle dermal papilla cell that is part of a scalp. http://purl.obolibrary.org/obo/UBERON_0007251 preoptic nucleus http://purl.obolibrary.org/obo/UBERON_0006569 diencephalic nucleus A nucleus of brain that is part of a preoptic area. http://purl.obolibrary.org/obo/CL_2000084 conjunctiva goblet cell http://purl.obolibrary.org/obo/CL_1000432 conjunctival epithelial cell A goblet cell that is part of the conjunctival epithelium, characterized by apical accumulation of mucin granules (containing MUC5AC in humans; Muc5ac/Muc5b in mice). These gel-forming mucins support tear film stability, ocular lubrication, and pathogen defence. The conjunctival goblet cell forms tight junctions with neighbouring epithelial cells via species-specific claudins (claudin-10 in humans, claudin-2 in mice) and regulates immune homeostasis by facilitating soluble antigen transport to dendritic cells through goblet cell-associated antigen passages (GAPs) (Barbosa et al., 2017). The transcription factor SPDEF is essential for its differentiation. http://purl.obolibrary.org/obo/UBERON_0007252 intervertebral disk of cervical vertebra http://purl.obolibrary.org/obo/UBERON_2001457 postcranial axial cartilage An intervertebral disk that is part of a cervical region of vertebral column. A cervical intervertebral disk connects at least one cervical vertebra, either to another cervical vertebra, or at one point on the vertebral colummn, to a thoracic vertebra. http://purl.obolibrary.org/obo/CL_2000085 mononuclear cell of umbilical cord http://purl.obolibrary.org/obo/CL_0000842 mononuclear leukocyte Any mononuclear cell that is part of a umbilical cord. http://purl.obolibrary.org/obo/UBERON_0007254 intervertebral disk of thoracic vertebra http://purl.obolibrary.org/obo/UBERON_2001457 postcranial axial cartilage An intervertebral disk that is part of a thoracic region of vertebral column. A thoracic intervertebral disk connects at least one thoracic vertebra, either to another thoracic vertebra, or at one point on the vertebral colummn, to a lumbar vertebra. http://purl.obolibrary.org/obo/CL_2000086 neocortex basket cell http://purl.obolibrary.org/obo/CL_0010011 cerebral cortex GABAergic interneuron Any basket cell that is part of a neocortex. http://purl.obolibrary.org/obo/UBERON_0007255 intervertebral disk of lumbar vertebra http://purl.obolibrary.org/obo/UBERON_2001457 postcranial axial cartilage An intervertebral disk that is part of a lumbar region of vertebral column. A lumbar intervertebral disk connects at least one lumbar vertebra, either to another thoracic vertebra, or at one point on the vertebral colummn, to a sacral vertebra. http://purl.obolibrary.org/obo/CL_2000087 dentate gyrus of hippocampal formation basket cell http://purl.obolibrary.org/obo/CL_4023062 dentate gyrus neuron Any basket cell that is part of a dentate gyrus of hippocampal formation. http://purl.obolibrary.org/obo/UBERON_0007257 intervertebral disk of sacral vertebra http://purl.obolibrary.org/obo/UBERON_2001457 postcranial axial cartilage An intervertebral disk that is part of a sacral region of vertebral column. A sacral intervertebral disk connects at least one sacral vertebra, either to another thoracic vertebra, or at one point on the vertebral colummn, to a sacral vertebra. http://purl.obolibrary.org/obo/CL_2000088 Ammon's horn basket cell http://purl.obolibrary.org/obo/CL_1001569 hippocampal interneuron Any basket cell that is part of a Ammon's horn. http://purl.obolibrary.org/obo/UBERON_0007266 intervertebral disk of atlas http://purl.obolibrary.org/obo/UBERON_0007252 intervertebral disk of cervical vertebra An intervertebral disk that connects a vertebral bone 1 and connects a vertebral bone 2. http://purl.obolibrary.org/obo/CL_2000089 dentate gyrus granule cell http://purl.obolibrary.org/obo/CL_4023062 dentate gyrus neuron A granule cell that has soma location in the dentate gyrus cell layer of the hippocampal formation and has an elliptical cell body and characteristic cone-shaped tree of spiny apical dendrites. The branches extend throughout the molecular layer and the distal tips of the dendritic tree end just at the hippocampal fissure or at the ventricular surface. The dentate gyrus granule cell is the principal cell type of the dentate gyrus. http://purl.obolibrary.org/obo/UBERON_0007267 trachea pre-cartilage rings http://purl.obolibrary.org/obo/UBERON_0009505 mesenchyme of trachea A pre-cartilage condensation that is part of a trachea. http://purl.obolibrary.org/obo/CL_2000090 dentate gyrus of hippocampal formation stellate cell http://purl.obolibrary.org/obo/CL_4023062 dentate gyrus neuron Any stellate cell that is part of a dentate gyrus of hippocampal formation. http://purl.obolibrary.org/obo/UBERON_0007269 pectoral appendage musculature http://purl.obolibrary.org/obo/UBERON_0014793 musculature of pectoral complex Any collection of muscles that is part of a pectoral appendage. http://purl.obolibrary.org/obo/CL_2000091 endometrial microvascular endothelial cell http://purl.obolibrary.org/obo/CL_0009095 endothelial cell of uterus Any microvascular endothelial cell that is part of a endometrial blood vessel. http://purl.obolibrary.org/obo/UBERON_0007270 pelvic appendage musculature http://purl.obolibrary.org/obo/UBERON_0014792 musculature of pelvic complex Any collection of muscles that is part of a pelvic appendage. http://purl.obolibrary.org/obo/CL_2000092 hair follicular keratinocyte http://purl.obolibrary.org/obo/CL_4052061 epidermal keratinocyte Any keratinocyte that is part of a hair follicle. http://purl.obolibrary.org/obo/UBERON_0007271 appendage musculature http://purl.obolibrary.org/obo/UBERON_0001015 musculature Any collection of muscles that is part of an appendage. http://purl.obolibrary.org/obo/CL_2000093 bronchus fibroblast of lung http://purl.obolibrary.org/obo/CL_0002553 fibroblast of lung Any fibroblast of lung that is part of a bronchus. http://purl.obolibrary.org/obo/UBERON_0007272 pectoral appendage skeleton http://purl.obolibrary.org/obo/UBERON_0011582 paired limb/fin skeleton Skeletal subdivision consisting of the anterior appendicular limb skeleton, excluding the pectoral girdle. http://purl.obolibrary.org/obo/CL_2000094 nasal cavity respiratory epithelium epithelial cell of viscerocranial mucosa http://purl.obolibrary.org/obo/CL_1000441 epithelial cell of viscerocranial mucosa Any epithelial cell of viscerocranial mucosa that is part of a nasal cavity respiratory epithelium. http://purl.obolibrary.org/obo/UBERON_0007273 pelvic appendage skeleton http://purl.obolibrary.org/obo/UBERON_0011582 paired limb/fin skeleton The collection of all skeletal elements in a pelvic appendage region. http://purl.obolibrary.org/obo/CL_2000095 cord blood hematopoietic stem cell http://purl.obolibrary.org/obo/CL_0002352 gestational hematopoietic stem cell Any hematopoietic stem cell that is part of a umbilical cord blood. http://purl.obolibrary.org/obo/UBERON_0007277 presumptive hindbrain http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure The rhombencephalon (or hindbrain) is a developmental categorization of portions of the central nervous system in vertebrates. The rhombencephalon can be subdivided in a variable number of transversal swellings called rhombomeres. In the human embryo eight rhombomeres can be distinguished, from caudal to rostral: Rh7-Rh1 and the isthmus (the most rostral rhombomere). A rare disease of the rhombencephalon, 'rhombencephalosynapsis' is characterized by a missing vermis resulting in a fused cerebellum. Patients generally present with cerebellar ataxia. The caudal rhombencephalon has been generally considered as the initiation site for neural tube closure. http://purl.obolibrary.org/obo/CL_2000096 fibroblast of the reticular layer of dermis http://purl.obolibrary.org/obo/CL_0002551 fibroblast of dermis A fibroblast of dermis that resides in the deep reticular layer, characterised by robust extracellular matrix production with high type I collagen deposition forming densely packed, organised fibrillar networks (Ghetti et al., 2018). This cell exhibits pro-fibrotic properties during wound healing, entering wounds early where it proliferates and deposits collagen to restore dermal architecture (Knoedler et al., 2023; McAndrews et al., 2022). It is distinguished from papillary dermal fibroblasts by expression of COL11A1, POSTN, and SPP1 in humans (Wu et al., 2022). http://purl.obolibrary.org/obo/UBERON_0007278 presumptive sinus venosus http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure Portion of tissue that is part of the heart tube and will become the sinus venosus. http://purl.obolibrary.org/obo/CL_2000097 midbrain dopaminergic neuron http://purl.obolibrary.org/obo/CL_2000029 central nervous system neuron Any dopaminergic neuron that is part of a midbrain. http://purl.obolibrary.org/obo/UBERON_0007280 presumptive endocardium http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure A presumptive structure that has the potential to develop into a endocardium. http://purl.obolibrary.org/obo/UBERON_0034978 paraganglion (generic) http://purl.obolibrary.org/obo/UBERON_0010313 neural crest-derived structure A cluster of neuroendocrine cells derived from neural crest. Paraganglia may be chromaffin or nonchromaffin. http://purl.obolibrary.org/obo/UBERON_0007281 presumptive midbrain hindbrain boundary http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure Embryonic structure that gives rise to the midbrain hindbrain boundary. http://purl.obolibrary.org/obo/UBERON_0034995 jaw mesenchyme http://purl.obolibrary.org/obo/UBERON_0003104 mesenchyme Mesenchyme that is part of a developing jaw [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0007282 presumptive segmental plate http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure A presumptive structure that has the potential to develop into a presomitic mesoderm. http://purl.obolibrary.org/obo/UBERON_0035034 eyelid epithelium http://purl.obolibrary.org/obo/UBERON_0015808 eye epithelium An epithelium that is part of an eyelid [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0007284 presumptive neural plate http://purl.obolibrary.org/obo/UBERON_0016879 future central nervous system A presumptive structure that has the potential to develop into a neural plate. http://purl.obolibrary.org/obo/UBERON_0035049 excretory duct of salivary gland http://purl.obolibrary.org/obo/UBERON_0035050 excretory duct Any of the interlobular excretory ducts of a salivary gland which are found in the connective tissue septa and formed by the union of several intralobular striated (secretory) ducts[MP,generalized]. http://purl.obolibrary.org/obo/UBERON_0007285 presumptive paraxial mesoderm http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure The part of the blastula that has the potential to develop into a paraxial mesoderm. http://purl.obolibrary.org/obo/UBERON_0035073 duct of eccrine sweat gland http://purl.obolibrary.org/obo/UBERON_0000058 duct A duct made up of simple tubular epithelium that is part of an eccrine sweat gland. The main function of the duct of the eccrine sweat gland is the reabsorption of Na and Cl ions as sweat flows through the duct. It has two cell layers: basal and luminal. It is continuous with the secretory coil and goes towards the skin surface. The distal segment of the duct is relatively straight and connects with the acrosyringium in the epidermis. Most of the ion reabsorption occurs in the proximal part of the duct. http://purl.obolibrary.org/obo/UBERON_0035267 neck of gallbladder http://purl.obolibrary.org/obo/UBERON_0001560 neck of organ The narrowest portion of the gallbladder and distal to the cystic duct. http://purl.obolibrary.org/obo/UBERON_0007286 presumptive floor plate http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure A presumptive structure that has the potential to develop into a floor plate. http://purl.obolibrary.org/obo/UBERON_0035316 prostatic capsule http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure The membrane the surrounds the prostate gland. http://purl.obolibrary.org/obo/UBERON_0007288 presumptive forebrain midbrain boundary http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure A presumptive structure that has the potential to develop into a forebrain-midbrain boundary. http://purl.obolibrary.org/obo/UBERON_0035553 left cardiac chamber http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure Any chamber of the left side of the heart. http://purl.obolibrary.org/obo/UBERON_0007289 presumptive rhombomere 1 http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure A presumptive structure that has the potential to develop into a rhombomere 1. http://purl.obolibrary.org/obo/UBERON_0035554 right cardiac chamber http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure Any chamber of the right side of the heart. http://purl.obolibrary.org/obo/UBERON_0007297 presumptive pronephric mesoderm http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure A presumptive structure that has the potential to develop into a pronephric mesoderm. http://purl.obolibrary.org/obo/UBERON_0035639 ocular adnexa http://purl.obolibrary.org/obo/UBERON_0034921 multi organ part structure The parts of the orbital region that are outside of the the eyeball, including the lacrimal apparatus, the extraocular muscles and the eyelids, eyelashes, eyebrows and the conjunctiva. http://purl.obolibrary.org/obo/UBERON_0007298 pronephric proximal convoluted tubule http://purl.obolibrary.org/obo/UBERON_0005310 pronephric nephron tubule A proximal convoluted tubule that is part of a pronephros. http://purl.obolibrary.org/obo/UBERON_0035804 future mouth http://purl.obolibrary.org/obo/UBERON_0013522 subdivision of tube The primordial mouth region of the developing head. http://purl.obolibrary.org/obo/UBERON_0007300 pectoral appendage blood vessel http://purl.obolibrary.org/obo/UBERON_0007301 appendage blood vessel A blood vessel that is part of a pectoral appendage. http://purl.obolibrary.org/obo/UBERON_0035805 muscle layer of sigmoid colon http://purl.obolibrary.org/obo/UBERON_0012489 muscle layer of colon A muscle layer that is part of the sigmoid colon. http://purl.obolibrary.org/obo/UBERON_0007301 appendage blood vessel http://purl.obolibrary.org/obo/UBERON_0001981 blood vessel A blood vessel that is part of a limb/fin. http://purl.obolibrary.org/obo/UBERON_0035820 peritoneal sac http://purl.obolibrary.org/obo/UBERON_0005906 serous sac A serous sac that is the aggregate of the peritoneum and the peritoneal cavity, located in the abdominal cavity. http://purl.obolibrary.org/obo/UBERON_0007302 pectoral appendage vasculature http://purl.obolibrary.org/obo/UBERON_0007304 appendage vasculature A vasculature that is part of a pectoral appendage. http://purl.obolibrary.org/obo/GO_1905952 regulation of lipid localization http://purl.obolibrary.org/obo/GO_0032879 regulation of localization Any process that modulates the frequency, rate or extent of lipid localization. http://purl.obolibrary.org/obo/UBERON_0007303 pharyngeal vasculature http://purl.obolibrary.org/obo/UBERON_0006876 vasculature of organ A vasculature that is part of a chordate pharynx. http://purl.obolibrary.org/obo/GO_1905953 negative regulation of lipid localization http://purl.obolibrary.org/obo/GO_1905952 regulation of lipid localization Any process that stops, prevents or reduces the frequency, rate or extent of lipid localization. http://purl.obolibrary.org/obo/UBERON_0007304 appendage vasculature http://purl.obolibrary.org/obo/UBERON_0002049 vasculature A vasculature that is part of a limb/fin. http://purl.obolibrary.org/obo/GO_1905954 positive regulation of lipid localization http://purl.obolibrary.org/obo/GO_1905952 regulation of lipid localization Any process that activates or increases the frequency, rate or extent of lipid localization. http://purl.obolibrary.org/obo/UBERON_0007306 pronephric glomerular capillary http://purl.obolibrary.org/obo/UBERON_0004212 glomerular capillary A glomerular capillary that is part of a pronephros. http://purl.obolibrary.org/obo/GO_1905957 regulation of cellular response to alcohol http://purl.obolibrary.org/obo/GO_1901419 regulation of response to alcohol Any process that modulates the frequency, rate or extent of cellular response to alcohol. http://purl.obolibrary.org/obo/UBERON_0007307 pronephric glomerular basement membrane http://purl.obolibrary.org/obo/UBERON_0005777 glomerular basement membrane A glomerular basement membrane that is part of a pronephros. http://purl.obolibrary.org/obo/GO_1905958 negative regulation of cellular response to alcohol http://purl.obolibrary.org/obo/GO_1905957 regulation of cellular response to alcohol Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to alcohol. http://purl.obolibrary.org/obo/UBERON_0007318 saphenous vein http://purl.obolibrary.org/obo/UBERON_0035550 superficial vein Either of two main superficial veins of the leg, one larger than the other, that begin at the foot. http://purl.obolibrary.org/obo/GO_1905959 positive regulation of cellular response to alcohol http://purl.obolibrary.org/obo/GO_1905957 regulation of cellular response to alcohol Any process that activates or increases the frequency, rate or extent of cellular response to alcohol. http://purl.obolibrary.org/obo/UBERON_0007324 pancreatic lobule http://purl.obolibrary.org/obo/UBERON_0000064 organ part A dense accumulation of exocrine glands in the pancreas often surrounding islets of Langerhans. http://purl.obolibrary.org/obo/GO_0140053 mitochondrial gene expression http://purl.obolibrary.org/obo/GO_0010467 gene expression The process in which a mitochondrial gene's sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form. http://purl.obolibrary.org/obo/UBERON_0007352 stria vascularis vasculature http://purl.obolibrary.org/obo/UBERON_0006876 vasculature of organ Blood vessels supplying the stria vascularis in the cochlea of the inner ear. http://purl.obolibrary.org/obo/UBERON_0007354 cartilage of pharyngotympanic tube http://purl.obolibrary.org/obo/UBERON_0007844 cartilage element A triangular plate of elastic fibrocartilage that forms the cartilage component of the pharyngotympanic tube. http://purl.obolibrary.org/obo/GO_0106027 neuron projection organization http://purl.obolibrary.org/obo/GO_0120036 plasma membrane bounded cell projection organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a neuron, e.g. an axon, or a dendrite. http://purl.obolibrary.org/obo/UBERON_0007355 bony part of pharyngotympanic tube http://purl.obolibrary.org/obo/UBERON_0003566 head connective tissue The bony part of pharyngotympanic tube is about 12 mm. in length. It begins in the carotid wall of the tympanic cavity, below the septum canalis musculotubarii, and, gradually narrowing, ends at the angle of junction of the squama and the petrous portion of the temporal bone, its extremity presenting a jagged margin which serves for the attachment of the cartilaginous portion. http://purl.obolibrary.org/obo/GO_0110021 cardiac muscle myoblast proliferation http://purl.obolibrary.org/obo/GO_0051450 myoblast proliferation The multiplication or reproduction of cardiac muscle myoblasts, resulting in the expansion of a cardiac muscle myoblast cell population. A cardiac myoblast is a precursor cell that has been committed to a cardiac muscle cell fate but retains the ability to divide and proliferate throughout life. http://purl.obolibrary.org/obo/UBERON_0007367 surface of tongue http://purl.obolibrary.org/obo/UBERON_0036215 anatomical surface region An anatomical surface that is part of a tongue. http://purl.obolibrary.org/obo/GO_0110022 regulation of cardiac muscle myoblast proliferation http://purl.obolibrary.org/obo/GO_2000291 regulation of myoblast proliferation Any process that modulates the frequency, rate or extent of cardiac muscle myoblast proliferation. http://purl.obolibrary.org/obo/UBERON_0007371 superior surface of tongue http://purl.obolibrary.org/obo/UBERON_0007367 surface of tongue The upper (superior) side of the tongue. http://purl.obolibrary.org/obo/GO_0110023 negative regulation of cardiac muscle myoblast proliferation http://purl.obolibrary.org/obo/GO_0110022 regulation of cardiac muscle myoblast proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle myoblast proliferation. http://purl.obolibrary.org/obo/UBERON_0007373 inferior surface of tongue http://purl.obolibrary.org/obo/UBERON_0007367 surface of tongue The lower (inferior) side of the tongue. http://purl.obolibrary.org/obo/GO_0110024 positive regulation of cardiac muscle myoblast proliferation http://purl.obolibrary.org/obo/GO_0110022 regulation of cardiac muscle myoblast proliferation Any process that activates or increases the frequency, rate or extent of cardiac muscle myoblast proliferation. http://purl.obolibrary.org/obo/UBERON_0007375 roof of mouth http://purl.obolibrary.org/obo/UBERON_0000481 multi-tissue structure A multi-tissue structure consisting of bone and soft tissue that forms a part of the roof of the oral cavity. In mammals this is the combination of the primary palate (premaxilla) and the secondary palate. In early tetrapods it consists of the vomer, pterygoid, parasphenoid, palatine and ectopterygoid bones. http://purl.obolibrary.org/obo/UBERON_0036224 corticobulbar and corticospinal tracts http://purl.obolibrary.org/obo/UBERON_0001018 axon tract The corticobulbar and corticospinal tracts combined. http://purl.obolibrary.org/obo/UBERON_0007376 outer epithelium http://purl.obolibrary.org/obo/UBERON_0003102 surface structure The epidermis is the entire outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species[GO]. http://purl.obolibrary.org/obo/UBERON_0036225 respiratory system gland http://purl.obolibrary.org/obo/UBERON_0002530 gland Any gland that is part os the respiratory system. http://purl.obolibrary.org/obo/UBERON_0007383 enveloping layer of ectoderm http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue Outermost layer of cells surrounding the embryo. http://purl.obolibrary.org/obo/GO_0099160 postsynaptic intermediate filament cytoskeleton http://purl.obolibrary.org/obo/GO_0099571 postsynaptic cytoskeleton The intermediate filament cytoskeleton that is part of a postsynapse. http://purl.obolibrary.org/obo/UBERON_0007384 appendage lymph vessel http://purl.obolibrary.org/obo/UBERON_0001473 lymphatic vessel A lymphatic vessel that is part of a limb/fin. http://purl.obolibrary.org/obo/UBERON_0036245 parenchyma of mammary gland http://purl.obolibrary.org/obo/UBERON_0000353 parenchyma Parenchymal tissue that consists of the alveoli, grape-like clusters where milk is stored, and branching ducts, which are tubular canals carrying gladular secretions. http://purl.obolibrary.org/obo/UBERON_0007385 pectoral appendage lymph vessel http://purl.obolibrary.org/obo/UBERON_0007384 appendage lymph vessel A lymphatic vessel that is part of a pectoral appendage. http://purl.obolibrary.org/obo/UBERON_0036248 joint of auditory ossicle http://purl.obolibrary.org/obo/UBERON_0002217 synovial joint Any synovial joint that connects auditory ossicles. http://purl.obolibrary.org/obo/UBERON_0007386 pelvic appendage lymph vessel http://purl.obolibrary.org/obo/UBERON_0007384 appendage lymph vessel A lymphatic vessel that is part of a pelvic appendage. http://purl.obolibrary.org/obo/GO_0120111 neuron projection cytoplasm http://purl.obolibrary.org/obo/GO_0005737 cytoplasm All of the contents of a plasma membrane bounded neuron projection, excluding the plasma membrane surrounding the projection. http://purl.obolibrary.org/obo/UBERON_0007389 paired limb/fin cartilage http://purl.obolibrary.org/obo/UBERON_0002418 cartilage tissue A cartilage tissue that is part of a paired limb or fin. http://purl.obolibrary.org/obo/GO_0110067 ammonium transmembrane transporter complex http://purl.obolibrary.org/obo/GO_1902495 transmembrane transporter complex High affinity ammonium transporter complex that enables the transfer of ammonium from one side of a membrane to the other. http://purl.obolibrary.org/obo/UBERON_0007390 pectoral appendage cartilage tissue http://purl.obolibrary.org/obo/UBERON_0007389 paired limb/fin cartilage A cartilage tissue that is part of a pectoral appendage. http://purl.obolibrary.org/obo/PATO_0045050 normal size http://purl.obolibrary.org/obo/PATO_0045001 normal object quality A size quality which is relatively normal or average http://purl.obolibrary.org/obo/UBERON_0007391 pelvic appendage cartilage tissue http://purl.obolibrary.org/obo/UBERON_0007389 paired limb/fin cartilage A cartilage tissue that is part of a pelvic appendage. http://purl.obolibrary.org/obo/GO_0061971 replacement bone morphogenesis http://purl.obolibrary.org/obo/GO_0060349 bone morphogenesis The process in which bones are generated and organized as a result of the conversion of another structural tissue into bone. http://purl.obolibrary.org/obo/UBERON_0007414 nucleus of midbrain tegmentum http://purl.obolibrary.org/obo/UBERON_0000125 neural nucleus A nucleus of brain that spans a midbrain tegmentum. http://purl.obolibrary.org/obo/GO_0061972 dermal bone morphogenesis http://purl.obolibrary.org/obo/GO_0061973 membrane bone morphogenesis The process in which bone which forms superficially in the organism are generated and organized. http://purl.obolibrary.org/obo/UBERON_0007415 nucleus of midbrain reticular formation http://purl.obolibrary.org/obo/UBERON_0009661 midbrain nucleus A nucleus of midbrain tegmentum that is part of a midbrain reticular formation. http://purl.obolibrary.org/obo/GO_0061973 membrane bone morphogenesis http://purl.obolibrary.org/obo/GO_0060349 bone morphogenesis The process in which bone which forms deep in the organism are generated and organized. http://purl.obolibrary.org/obo/UBERON_0007416 cerebellar peduncle http://purl.obolibrary.org/obo/UBERON_0014891 brainstem white matter Any of the three large paired bundles of nerve fibers that connect the cerebellum to the brain stem. http://purl.obolibrary.org/obo/GO_0062137 cargo receptor complex http://purl.obolibrary.org/obo/GO_0098796 membrane protein complex Any protein complex that is part of a membrane and which functions as a cargo receptor. http://purl.obolibrary.org/obo/UBERON_0007418 neural decussation http://purl.obolibrary.org/obo/UBERON_0011215 central nervous system cell part cluster Nerve fibers crossing the midline of the neuraxis relative to their point of origin, on a course to from one level of the nervous system to another. (CUMBO, Heimer, L. The Human Brain, 2nd ed., 1995, pg 6). http://purl.obolibrary.org/obo/GO_0140513 nuclear protein-containing complex http://purl.obolibrary.org/obo/GO_0032991 protein-containing complex A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together in the nucleus. http://purl.obolibrary.org/obo/UBERON_0007425 decussation of diencephalon http://purl.obolibrary.org/obo/UBERON_0007418 neural decussation A neural decussation that is part of a diencephalon. http://purl.obolibrary.org/obo/GO_0140546 defense response to symbiont http://purl.obolibrary.org/obo/GO_0098542 defense response to other organism Reactions triggered in response to the presence of a symbiont that act to protect or prevent damage to the host. http://purl.obolibrary.org/obo/UBERON_0007473 lumen of epithelial sac http://purl.obolibrary.org/obo/UBERON_0012467 enclosed anatomical space The space within an epithelial sphere. http://purl.obolibrary.org/obo/UBERON_8400006 liver lobule periportal region http://purl.obolibrary.org/obo/UBERON_8400005 metabolic zone of liver The region of the liver lobule that is closest to the portal triad. The functionally-defined hepatic acinus zone 1 is generally found in this region. http://purl.obolibrary.org/obo/UBERON_8400007 liver lobule centrilobular region http://purl.obolibrary.org/obo/UBERON_8400005 metabolic zone of liver The region of the liver lobule that is closest to the central vein. The functionally-defined hepatic acinus zone 3 is generally found in this region. http://purl.obolibrary.org/obo/UBERON_0007475 matrix-based tissue http://purl.obolibrary.org/obo/UBERON_0000479 tissue A tissue whose predominant feature is extracellular matrix which may or may not be highly hydrated or calcified. http://purl.obolibrary.org/obo/UBERON_8400008 liver lobule midzonal region http://purl.obolibrary.org/obo/UBERON_8400005 metabolic zone of liver The region of the liver lobule that is between the periportal and centrilobular regions. The functionally-defined hepatic acinus zone 2 is generally found in this region. http://purl.obolibrary.org/obo/UBERON_0007490 keratin-based acellular structure http://purl.obolibrary.org/obo/UBERON_0000476 acellular anatomical structure Acellular anatomical structure whose predominant constituent is keratin. http://purl.obolibrary.org/obo/CL_0009007 gastrointestinal tract (lamina propria) macrophage of small intestine http://purl.obolibrary.org/obo/CL_0000865 gastrointestinal tract (lamina propria) macrophage A macrophage which is resident in the lamina propria of the small intestine. http://purl.obolibrary.org/obo/UBERON_0007499 epithelial sac http://purl.obolibrary.org/obo/UBERON_0009856 sac An epithelial tube that is open at one end only. http://purl.obolibrary.org/obo/CL_0009008 gastrointestinal tract (lamina propria) macrophage of large intestine http://purl.obolibrary.org/obo/CL_0000865 gastrointestinal tract (lamina propria) macrophage A macrophage which is resident in the lamina propria of the large intestine. http://purl.obolibrary.org/obo/UBERON_0007500 epithelial tube open at both ends http://purl.obolibrary.org/obo/UBERON_0003914 epithelial tube An epithelial tube open at both ends that allows fluid flow. http://purl.obolibrary.org/obo/CL_0009021 stromal cell of lamina propria of large intestine http://purl.obolibrary.org/obo/CL_0000499 stromal cell A stromal cell found in the lamina propria of the large intestine. http://purl.obolibrary.org/obo/UBERON_0007501 arborizing epithelial duct system http://purl.obolibrary.org/obo/UBERON_0007499 epithelial sac A collection of connected epithelial tubes with a single portal. http://purl.obolibrary.org/obo/CL_0009022 stromal cell of lamina propria of small intestine http://purl.obolibrary.org/obo/CL_0000499 stromal cell A stromal cell found in the lamina propria of the small intestine. http://purl.obolibrary.org/obo/UBERON_0007503 epithelial vesicle http://purl.obolibrary.org/obo/UBERON_0000483 epithelium A closed epithelium with a lumen. http://purl.obolibrary.org/obo/CL_0009023 small intestine Peyer's patch T cell http://purl.obolibrary.org/obo/CL_0009014 Peyer's patch lymphocyte A T cell which resides in the Peyer's patch of the small intestine. http://purl.obolibrary.org/obo/UBERON_0007521 smooth muscle sphincter http://purl.obolibrary.org/obo/UBERON_0004590 sphincter muscle A ring of smooth muscle cells whose contraction closes the opening of the ring. http://purl.obolibrary.org/obo/CL_0009024 mesothelial cell of small intestine http://purl.obolibrary.org/obo/CL_0008041 mesothelial cell of intestine A mesothelial cell that is part of the small intestine. http://purl.obolibrary.org/obo/UBERON_0007522 striated muscle sphincter http://purl.obolibrary.org/obo/UBERON_0004590 sphincter muscle A ring of striated muscle cells whose contraction closes the opening of the ring. http://purl.obolibrary.org/obo/CL_0009025 mesothelial cell of colon http://purl.obolibrary.org/obo/CL_0008041 mesothelial cell of intestine A mesothelial cell that is part of the colon. http://purl.obolibrary.org/obo/UBERON_0007524 dense mesenchyme tissue http://purl.obolibrary.org/obo/UBERON_0003104 mesenchyme Mesenchyme with little extracellular matrix. http://purl.obolibrary.org/obo/CL_4023007 L2/3 bipolar VIP GABAergic interneuron (Mmus) http://purl.obolibrary.org/obo/CL_4023016 VIP GABAergic interneuron A VIP GABAergic cortical interneuron with bipolar morphology, with a soma found in L2/3. L2/3 bipolar VIP cells have extending axons across all layers (with preferences for layers II/III and Va) and a dendritic tree that is vertically more restricted than deeper layer VIP cells and extend fewer dendrites into the layers outside their home layer (location of soma). L2/3 bipolar VIP cells have great variability in firing patterns, though most are continuous adapting. L2/3 bipolar VIP cells are more depolarized in their resting state, had less fast rectification, and had smaller after hyperpolarization than deeper VIP cells. http://purl.obolibrary.org/obo/UBERON_0007529 loose mesenchyme tissue http://purl.obolibrary.org/obo/UBERON_0003104 mesenchyme Mesenchyme whose cells are embedded in obvious amounts of extracellular matrix. http://purl.obolibrary.org/obo/CL_4023008 intratelencephalic-projecting glutamatergic cortical neuron http://purl.obolibrary.org/obo/CL_0010012 cerebral cortex neuron A glutamatergic neuron located in the cerebral cortex that projects to structures of telencephalic origins. http://purl.obolibrary.org/obo/UBERON_0007530 migrating mesenchyme population http://purl.obolibrary.org/obo/UBERON_0003104 mesenchyme Mesenchymal cells that are migrating. http://purl.obolibrary.org/obo/CL_4023009 extratelencephalic-projecting glutamatergic cortical neuron http://purl.obolibrary.org/obo/CL_0010012 cerebral cortex neuron A glutamatergic neuron located in the cerebral cortex that projects to structures not derived from telencephalon. http://purl.obolibrary.org/obo/UBERON_0007567 regenerating anatomical structure http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure An anatomical structure that is undergoing regeneration. http://purl.obolibrary.org/obo/CL_4023012 near-projecting glutamatergic cortical neuron http://purl.obolibrary.org/obo/CL_0010012 cerebral cortex neuron A glutamatergic neuron located in the cerebral cortex that projects axons locally rather than distantly. http://purl.obolibrary.org/obo/UBERON_0007589 ciliated columnar oviduct epithelium http://purl.obolibrary.org/obo/UBERON_0007592 ciliated columnar epithelium A ciliated columnar epithelium that is part of a oviduct. http://purl.obolibrary.org/obo/CL_4023013 corticothalamic-projecting glutamatergic cortical neuron http://purl.obolibrary.org/obo/CL_0010012 cerebral cortex neuron A glutamatergic neuron located in the cerebral cortex that projects to the thalamus. http://purl.obolibrary.org/obo/UBERON_0007590 cuboidal oviduct epithelium http://purl.obolibrary.org/obo/UBERON_0010077 cuboidal epithelium A cuboidal epithelium that is part of a oviduct. http://purl.obolibrary.org/obo/CL_4023014 L5 VIP GABAergic interneuron (Mmus) http://purl.obolibrary.org/obo/CL_4023016 VIP GABAergic interneuron A VIP GABAergic cortical interneuron with a soma found in L5. L5 VIP cells have mostly local morphology with some deep-projecting axons. They show only moderate resistance, comparable to that of sst subclass and unlike typical VIP subclass cells that tend to show high input resistance. L5 VIP cells show particularly low resting membrane potential. http://purl.obolibrary.org/obo/UBERON_0007592 ciliated columnar epithelium http://purl.obolibrary.org/obo/UBERON_0007601 ciliated epithelium Simple columnar epithelium in which the luminal side of the cells bears cilia. Examples: epithelium of trachea, epithelium of uterine tube.[FMA]. http://purl.obolibrary.org/obo/CL_4023019 L5/6 cck, VIP GABAergic interneuron (Mmus) http://purl.obolibrary.org/obo/CL_4023071 L5/6 cck GABAergic interneuron (Mmus) A VIP GABAergic cortical interneuron that expresses cck. L5/6 cck cells have soma found mainly in L5 and L6 and have large axonal arborization. http://purl.obolibrary.org/obo/UBERON_0007601 ciliated epithelium http://purl.obolibrary.org/obo/UBERON_0000483 epithelium Epithelium bearing vibratile cilia on the free surface. http://purl.obolibrary.org/obo/CL_4023022 canopy lamp5 GABAergic cortical interneuron (Mmus) http://purl.obolibrary.org/obo/CL_4023011 lamp5 GABAergic interneuron A Lamp5 GABAergic cortical interneuron that has extended axons in the surface of L1. Canopy Lamp5 cells resemble neurogliaform cells in having elongated horizontal axonal arbors largely confined to L1; but the dendritic arbors are wider and have fewer branches, while the axon is less tortuous and extends further from the soma http://purl.obolibrary.org/obo/UBERON_0007602 stratified columnar epithelium http://purl.obolibrary.org/obo/UBERON_0012274 columnar epithelium Stratified columnar epithelia is a rare type of epithelial tissue composed of column shaped cells arranged in multiple layers. Stratified columnar epithelia are found in the ocular conjunctiva of the eye, in parts of the pharynx and anus, the female's uterus, the male urethra and vas deferens. Also found in intralobular ducts in salivary glands.[WP]. http://purl.obolibrary.org/obo/CL_4023023 L5,6 neurogliaform lamp5 GABAergic interneuron (Mmus) http://purl.obolibrary.org/obo/CL_4023011 lamp5 GABAergic interneuron A lamp 5 GABAergic cortical interneuron with neurogliaform morphology with a soma found in L5,6. L5,6 NGC lamp5 have deep afterhyperpolarization (AHP) but narrow action potentials (APs). Unlike other deep neurogliaform cells (which are caudal ganglionic eminence (CGE) derived), L5,6 NGC lamp5 cells are medial ganglionic eminence (MGE)-derived http://purl.obolibrary.org/obo/UBERON_0007617 synovial cavity of joint http://purl.obolibrary.org/obo/UBERON_0002553 anatomical cavity An anatomical cavity that surrounded_by a synovial joint. http://purl.obolibrary.org/obo/CL_4023024 neurogliaform lamp5 GABAergic cortical interneuron (Mmus) http://purl.obolibrary.org/obo/CL_4023011 lamp5 GABAergic interneuron A lamp5 GABAergic cortical interneuron with layer-adapting morphology. NGC lamp5 cells have a small round soma, short dendrites, and a wide dense axonal arbor that tends to establish a dense axonal mesh with high connection probability both to themselves and L2 pyramidal cells. NGC lamp5 cells have unique synaptic properties that distinguish them from other GABAergic interneurons, including the release of GABA to the extracellular space via volume transmission, and the ability to produce GABA-B responses in connected postsynaptic targets. http://purl.obolibrary.org/obo/UBERON_0007625 pigment epithelium of eye http://purl.obolibrary.org/obo/UBERON_0019304 sensory organ epithelium Epithelial layer of the retina, ciliary body, or iris composed of cells containing pigment granules. http://purl.obolibrary.org/obo/CL_4023025 long-range projecting sst GABAergic cortical interneuron (Mmus) http://purl.obolibrary.org/obo/CL_4023121 sst chodl GABAergic interneuron A sst GABAergic cortical interneuron that is both an interneuron and a projecting neuron. They are found in all layers from upper L2/3 down to the bottom of L6. They have long-range projections, some with axons fading into white matter. These cells have low rebound potential, low hyperpolarization sag, and high variability in membrane time constant. http://purl.obolibrary.org/obo/UBERON_0007628 lateral septal complex http://purl.obolibrary.org/obo/UBERON_0002663 septal nuclear complex The lateral septal area; largest nuclear mass in this region, plays a pivotal role in various physiological processes, such as aggression, emotion, thermoregulation, water and food intake and sexual behaviour. http://purl.obolibrary.org/obo/CL_4023027 L5 sst T-Martinotti interneuron (Mmus) http://purl.obolibrary.org/obo/CL_4023086 T Martinotti neuron A sst GABAergic cortical interneuron with a soma found in L5 and possesses 'T-shaped' Martinotti morphologies with local axonal plexus in L5a and translaminar axons restricted to the uppermost part of L1. They show low-threshold spiking patterns with strong rebound firing, and inhibit the L1 apical tuft of nearby pyramidal cells. http://purl.obolibrary.org/obo/UBERON_0007629 medial septal complex http://purl.obolibrary.org/obo/UBERON_0002663 septal nuclear complex A septal nuclear complex that consists of the nucleus of the diagonal bands and the septal medial nuclei. http://purl.obolibrary.org/obo/CL_4023028 L5 non-Martinotti sst GABAergic interneuron (Mmus) http://purl.obolibrary.org/obo/CL_0010011 cerebral cortex GABAergic interneuron A sst GABAergic cortical interneuron with a soma found in lower L5 with mostly local axonal arborization but with some sparse ascending axons. L5 non-Martinotti sst cells show somatic localization and local axon plexus in L5b and L5b/6 and substantial innervation of L3 and L4, and receive thalamic input from the ventral posteromedial nucleus and specifically target L4 neurons, avoiding L5 pyramidal cells. L5 non-Martinotti sst cells tend to show a higher input resistance and seem to be less stuttering. http://purl.obolibrary.org/obo/UBERON_0007635 nucleus of medulla oblongata http://purl.obolibrary.org/obo/UBERON_0009662 hindbrain nucleus A neural nucleus that is part of a medulla oblongata. http://purl.obolibrary.org/obo/CL_4023030 L2/3/5 fan Martinotti sst GABAergic interneuron (Mmus) http://purl.obolibrary.org/obo/CL_0010011 cerebral cortex GABAergic interneuron A sst GABAergic cortical interneuron that has "fanning-out' Martinotti morphology that is found in layer 2/3/5 of the cerebral cortex. They have local axon arbor and long ascending axons that spreads horizontally and arborizes significantly in L1. http://purl.obolibrary.org/obo/UBERON_0007637 hippocampus stratum lucidum http://purl.obolibrary.org/obo/UBERON_0002305 layer of hippocampus Layer of hippocampus area CA3 lying superficial to the pyramidal cell layer that contains mossy fiber axons projecting from the dentate gyrus. A slight thickening in this layer marks the border in some species between areas CA2 and CA3. dapted from Paxinos, G. The rat central nervous system, 2nd ed, Academic Press, San Diego, 1995, pg. 460). http://purl.obolibrary.org/obo/CL_4023031 L4 sst Martinotti interneuron (Mmus) http://purl.obolibrary.org/obo/CL_4023076 Martinotti neuron A sst GABAergic cortical interneuron with a soma found in lower L2/3 and upper 5, L4 Sst cells have Martinotti morphology with ascending axons but denser local axons and sparser ‘fanning-out’ projections to L1. L4 sst cells have smaller membrane time constant to calb2 (L2/3/5 fan Martinotti Cell) and non-zero afterdepolarization (ADP). http://purl.obolibrary.org/obo/UBERON_0007639 hippocampus alveus http://purl.obolibrary.org/obo/UBERON_0016549 central nervous system white matter layer Regional part of fornix consisting of a thin layer of white matter on the surface of the hippocampal formation, bordering the wall of the lateral ventricle and composed of white, myelinated fibers. The alveus arises from cell bodies in the subiculum and hippocampus, and eventually merges with the fimbria of the hippocampus. The fimbria goes on to become the fornix (MM: 2006-10-26). http://purl.obolibrary.org/obo/CL_4023036 pvalb chandelier GABAergic interneuron http://purl.obolibrary.org/obo/CL_4023069 medial ganglionic eminence derived GABAergic interneuron A transcriptomically distinct pvalb GABAergic interneuron located in the pallium. It is recognizable by the straight terminal axonal 'cartridges' of vertically oriented strings of synaptic boutons. Chandelier PV cells' boutons target exclusively the axon initial segment (AIS) of pyramidal cells, with a single cell innervating hundreds of pyramidal cells in a clustered manner. These cells are fast-spiking. http://purl.obolibrary.org/obo/UBERON_0007641 trigeminal nuclear complex http://purl.obolibrary.org/obo/UBERON_0007245 nuclear complex of neuraxis The sensory trigeminal nerve nuclei are the largest of the cranial nerve nuclei, and extend through the whole of the midbrain, pons and medulla. There is also a distinct trigeminal motor nucleus that is medial to the chief sensory nucleus[WP]. http://purl.obolibrary.org/obo/CL_4023069 medial ganglionic eminence derived GABAergic interneuron http://purl.obolibrary.org/obo/CL_4023063 medial ganglionic eminence derived interneuron A GABAergic interneuron that develops from the medial ganglionic eminence and has migrated to the cerebral cortex. http://purl.obolibrary.org/obo/UBERON_0007644 thoracic lymph node http://purl.obolibrary.org/obo/UBERON_0005181 thoracic segment organ A lymph node that is part of a thorax. Includes lymph nodes of the lungs and mediastinal lymph nodes. http://purl.obolibrary.org/obo/CL_0009035 stromal cell of lamina propria of vermiform appendix http://purl.obolibrary.org/obo/CL_0009021 stromal cell of lamina propria of large intestine A stromal cell found in the lamina propria of the vermiform appendix. http://purl.obolibrary.org/obo/UBERON_0007645 future meninx http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure A developing mesenchymal capsule that covers the developing brain and spinal cord and is the precursor of the meningeal cluster. In mammals this gives rise to the arachnoid mater, pia mater and dura mater. In cyclostomes and fishes, the future meninx gives rise to a single meningeal layer, the primitive meninx. http://purl.obolibrary.org/obo/CL_0017506 banded nucleus http://purl.obolibrary.org/obo/GO_0005634 nucleus A concave nuclear shape where the nucleus is indented to more than half the distance to the farthest nuclear margin, but in no area is the chromatin condensed to a single filament. http://purl.obolibrary.org/obo/UBERON_0007646 endomeninx http://purl.obolibrary.org/obo/UBERON_0007645 future meninx The innermost layer of the mesenchymal capsule that surrounds the developing brain, primarily of neural crest origin. The endomeninx forms the leptomeninx. http://purl.obolibrary.org/obo/CL_0017508 cartwheel heterochromatin http://purl.obolibrary.org/obo/GO_0000792 heterochromatin Heterochromatin that is arranged in a carthwheel pattern. http://purl.obolibrary.org/obo/UBERON_0007647 ectomeninx http://purl.obolibrary.org/obo/UBERON_0007645 future meninx The outermost layer of the mesenchymal capsule that surrounds the developing brain, of mixed paraxial mesoderm and neural crest origin. The ectomeninx forms the dura mater (both inner layer and outer chondrogenic layer). http://purl.obolibrary.org/obo/CL_4023075 L6 th sst GABAergic interneuron (Mmus) http://purl.obolibrary.org/obo/CL_0010011 cerebral cortex GABAergic interneuron A sst GABAergic cortical interneuron found in L6 that expresses tyrosine hydroxylase. L6 Th+ SST cells have mostly local axonal arborization within L6. http://purl.obolibrary.org/obo/UBERON_0007651 anatomical junction http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure An anatomical structure that connects two structures. http://purl.obolibrary.org/obo/CL_4023121 sst chodl GABAergic interneuron http://purl.obolibrary.org/obo/CL_4023017 sst GABAergic interneuron A transcriptomically distinct sst GABAergic interneuron that also expresses Chodl. These neurons are rare and correspond to the only known interneurons with long-range projection. http://purl.obolibrary.org/obo/UBERON_0007652 esophageal sphincter http://purl.obolibrary.org/obo/UBERON_0004590 sphincter muscle A sphincter that is part of an esophagus. http://purl.obolibrary.org/obo/CL_0009100 hepatic portal fibroblast http://purl.obolibrary.org/obo/CL_0000057 fibroblast A fibroblast located in the portal triad. Hepatic portal fibroblast are a non-parenchymal cell population located adjacent to bile duct epithelia in liver and are distinct from stellate cells. They differentiate into fibrogenic myofibroblasts during chronic injury states producing high levels of collagen. http://purl.obolibrary.org/obo/UBERON_0007684 uriniferous tubule http://purl.obolibrary.org/obo/UBERON_0006555 excretory tube Functional unit of the kidney that forms urine, consisting of two parts, the nephron and the collecting tubule. http://purl.obolibrary.org/obo/UBERON_8410081 blood microvessel http://purl.obolibrary.org/obo/UBERON_0010523 microcirculatory vessel Any of the smallest blood vessels where blood circulates within organ tissues. Microvessels include terminal arterioles, metarterioles, capillaries, and venules (but exclude lymphatic capillaries). Arterioles carry oxygenated blood to the capillaries, and blood flows out of the capillaries through venules into veins. http://purl.obolibrary.org/obo/UBERON_0007687 kidney field http://purl.obolibrary.org/obo/UBERON_0007688 anlage Region of the embryo into the area in which the kidney rudiment will develop. http://purl.obolibrary.org/obo/GO_0120331 endothelial tube formation http://purl.obolibrary.org/obo/GO_0072175 epithelial tube formation The developmental process pertaining to the initial formation of an endothelial tube. http://purl.obolibrary.org/obo/UBERON_0007688 anlage http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure Anlagen are populations of contiguous cells, typically arranged in one plane, that are morphologically indistinct, but that already correspond in extent to a later organ/tissue. http://purl.obolibrary.org/obo/CL_4023168 somatosensory neuron http://purl.obolibrary.org/obo/CL_2000032 peripheral nervous system neuron A neuron that is part of the somatic sensory system. Somatosensory neurons innervate the skin or integument to detect different types of thermal, chemical, and mechanical touch stimuli. http://purl.obolibrary.org/obo/UBERON_0007689 thyroid diverticulum http://purl.obolibrary.org/obo/UBERON_0001048 primordium Endodermal bud derived from the endodermal epithelium of the embryonic pharyngeal floor[MP]. The thyroid diverticulum is the embryological structure from which thyroid follicular cells derive. It grows from the floor of the pharnyx[WP]. http://purl.obolibrary.org/obo/CL_4023169 trigeminal neuron http://purl.obolibrary.org/obo/CL_2000029 central nervous system neuron A neuron that is responsible for sensation in the face or motor functions such as biting and chewing. Trigeminal neurons extend a single axon shaft along the lateral white matter of the hindbrain and spinal cord. The highly branched axons innervate the integument of the head. http://purl.obolibrary.org/obo/UBERON_0007691 gustatory pore http://purl.obolibrary.org/obo/UBERON_0000161 orifice The minute opening of a taste bud on the surface of the oral mucosa through which the gustatory hairs of the specialised neuroepithelial gustatory cells project. http://purl.obolibrary.org/obo/CL_0017006 B-lymphoblast http://purl.obolibrary.org/obo/CL_0017005 lymphoblast A lymphocyte of B lineage that has gotten larger after being stimulated by an antigen. http://purl.obolibrary.org/obo/UBERON_0007692 nucleus of thalamus http://purl.obolibrary.org/obo/UBERON_0006569 diencephalic nucleus A nucleus of brain that is part of a thalamus. http://purl.obolibrary.org/obo/UBERON_0007699 tract of spinal cord http://purl.obolibrary.org/obo/UBERON_0001018 axon tract An axon tract that is part of a spinal cord. http://purl.obolibrary.org/obo/CL_0004117 alpha retinal ganglion cell (Mmus) http://purl.obolibrary.org/obo/CL_0000740 retinal ganglion cell A large-bodied retinal projection neuron with wide monostratified dendritic arbors in defined IPL strata, high neurofilament and osteopontin expression, and a thick, fast-conducting axon. It shows short-latency, non-direction-selective responses with large receptive fields and a distinctive rapid action potential waveform. In mammals it forms about five percent of RGCs and includes four conserved ON and OFF sustained and transient subtypes. http://purl.obolibrary.org/obo/UBERON_0007702 tract of brain http://purl.obolibrary.org/obo/UBERON_0001018 axon tract An axon tract that is part of a brain. http://purl.obolibrary.org/obo/CL_0004253 wide field retinal amacrine cell http://purl.obolibrary.org/obo/CL_0000561 amacrine cell An amicrine that has a wide dendritic field. http://purl.obolibrary.org/obo/UBERON_0007719 bone of reproductive organ http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure A bone that is part of a reproductive organ. http://purl.obolibrary.org/obo/CL_0004227 flat bistratified amacrine cell http://purl.obolibrary.org/obo/CL_4030028 glycinergic amacrine cell A bistratified amacrine cell with a small dendritic field. Flat bistratified amacrine cells have post-synaptic terminals both on the border of S1 and S2, and on the border of S3 and S4. This cell type releases the neurotransmitter glycine. http://purl.obolibrary.org/obo/UBERON_0007721 interphalangeal joint of pes http://purl.obolibrary.org/obo/UBERON_0006658 interphalangeal joint The interphalangeal articulations of the foot (articulations of the phalanges) are ginglymoid joints, and each has a plantar and two collateral ligaments. The arrangement of these ligaments is similar to that in the metatarsophalangeal articulations: the Extensor tendons supply the places of dorsal ligaments. http://purl.obolibrary.org/obo/CL_0003011 G8 retinal ganglion cell http://purl.obolibrary.org/obo/CL_0000740 retinal ganglion cell A mono-stratified retinal ganglion cell that has a large dendritic field and a sparse dendritic arbor with post synaptic terminals in sublaminar layer S4. http://purl.obolibrary.org/obo/UBERON_0007722 interphalangeal joint of manus http://purl.obolibrary.org/obo/UBERON_0006658 interphalangeal joint The interphalangeal articulations of hand are hinge-joints of the phalanges of the hand. There are two sets (except in the thumb): 'proximal interphalangeal joints' (PIP), those between the first (also called proximal) and second (intermediate) phalanges 'distal interphalangeal joints' (DIP), those between the second and third (distal) phalanges A similar group of articulations also function in the toes. http://purl.obolibrary.org/obo/UBERON_0007771 epidermis gland http://purl.obolibrary.org/obo/UBERON_0002419 skin gland A gland that is part of a epidermis. http://purl.obolibrary.org/obo/CL_0004120 retinal ganglion cell A1 http://purl.obolibrary.org/obo/CL_0004117 alpha retinal ganglion cell (Mmus) A retinal ganglion A cell found in the retina with large somata, often polygonal in shape. The dendritic fields consist of three to seven stout dendrites that are sparce near soma. Dendrites terminate in S4. http://purl.obolibrary.org/obo/UBERON_0007777 umbilical vein endothelium http://purl.obolibrary.org/obo/UBERON_0001919 endothelium of vein An endothelium that is part of a umbilical vein. http://purl.obolibrary.org/obo/UBERON_0007778 umbilical artery endothelium http://purl.obolibrary.org/obo/UBERON_0001917 endothelium of artery An endothelium that is part of a umbilical artery. http://purl.obolibrary.org/obo/CL_0004119 retinal ganglion cell B1 http://purl.obolibrary.org/obo/CL_0004115 retinal ganglion cell B A retinal ganglion cell B that has medium body size, medium dendritic field and dense dendritic arbor, and has post synaptic terminals in S2. http://purl.obolibrary.org/obo/UBERON_0007779 transudate http://purl.obolibrary.org/obo/UBERON_0006314 bodily fluid Any bodily fluid that has passed through a membrane such as the capillary wall, as a result of unbalanced hydrostatic and osmotic forces. http://purl.obolibrary.org/obo/CL_0004244 WF4 amacrine cell http://purl.obolibrary.org/obo/CL_0004253 wide field retinal amacrine cell An amacrine cell with a wide dendritic field, dendrites in S4, and post-synaptic terminals in S4. http://purl.obolibrary.org/obo/UBERON_0007794 secretion of serous gland http://purl.obolibrary.org/obo/UBERON_0006314 bodily fluid Any fluid produced by a serous gland. http://purl.obolibrary.org/obo/CL_0003016 G11-OFF retinal ganglion cell http://purl.obolibrary.org/obo/CL_0003014 G11 retinal ganglion cell A G11 retinal ganglion cell that has post synaptic terminals in sublaminar layer S2 and is depolarized by decreased illumination of their receptive field center http://purl.obolibrary.org/obo/UBERON_0007806 connecting stalk http://purl.obolibrary.org/obo/UBERON_0000478 extraembryonic structure A bridge of mesoderm connecting the caudal end of the young embryo with the trophoblastic tissues; the precursor of the umbilical cord. http://purl.obolibrary.org/obo/CL_0004121 retinal ganglion cell B2 http://purl.obolibrary.org/obo/CL_0004115 retinal ganglion cell B A retinal ganglion cell B that has a very small but very dense dendritic field, and has post synaptic terminals in S2. http://purl.obolibrary.org/obo/UBERON_0007807 connecting stalk vasculature http://purl.obolibrary.org/obo/UBERON_0002049 vasculature A vasculature that is part of a connecting stalk. http://purl.obolibrary.org/obo/CL_0004214 type 3b cone bipolar cell http://purl.obolibrary.org/obo/CL_0000755 type 3 cone bipolar cell (sensu Mus) A type of type 3 cone bipolar cell with distinctive crescent-shaped dendrites. http://purl.obolibrary.org/obo/UBERON_0007808 adipose tissue of abdominal region http://purl.obolibrary.org/obo/UBERON_0003567 abdomen connective tissue Adipose tissue that is located in the abdominal region. This includes any subcutaneous fat, visceral fat or encapsulated adipose tissue depots. http://purl.obolibrary.org/obo/CL_4023061 hippocampal CA4 neuron http://purl.obolibrary.org/obo/CL_2000029 central nervous system neuron A neuron that has its soma located in CA4 of the hippocampus. http://purl.obolibrary.org/obo/UBERON_0007811 craniocervical region http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision The anteriormost subdivision of the body that includes the head, jaws, pharyngeal region and the neck (if present). In vertebrates this is the subdivision that includes the cervical vertebrae. http://purl.obolibrary.org/obo/CL_4023079 midbrain-derived inhibitory neuron http://purl.obolibrary.org/obo/CL_2000029 central nervous system neuron A GABAergic inhibitory neuron that is derived from the midbrain. http://purl.obolibrary.org/obo/UBERON_0007812 post-anal tail http://purl.obolibrary.org/obo/UBERON_0002415 tail A tail that extends from the posterior tip of the organism to the anus, contains muscle and skeleton. http://purl.obolibrary.org/obo/CL_4023188 midget ganglion cell of retina http://purl.obolibrary.org/obo/CL_0000740 retinal ganglion cell A retinal ganglion cell that originate in the ganglion cell layer of the retina, and project to the parvocellular layers of the lateral geniculate nucleus (LGN). These cells are known as midget retinal ganglion cells due to the small sizes of their dendritic trees and cell bodies. http://purl.obolibrary.org/obo/UBERON_0007823 appendage girdle region http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision An organism subdivision that encompasses the region containing the pectoral or pelvic girdle. Note that this includes both the skeletal elements and associated tissues (integument, muscle, etc). http://purl.obolibrary.org/obo/CL_4023189 parasol ganglion cell of retina http://purl.obolibrary.org/obo/CL_0000740 retinal ganglion cell A retinal ganglion cell located in the ganglion cell layer of the retina. This cell projects to magnocellular cells in the lateral geniculate nucleus (LGN). They have large cell bodies and extensive, branching dendritic networks that contribute to their large receptive fields. http://purl.obolibrary.org/obo/UBERON_0007826 peritoneal mesentery http://purl.obolibrary.org/obo/UBERON_0002095 mesentery Mesentery that is located in the peritoneum. http://purl.obolibrary.org/obo/CL_4030067 L5/6 near-projecting glutamatergic neuron http://purl.obolibrary.org/obo/CL_4023012 near-projecting glutamatergic cortical neuron A transcriptomically defined near-projecting glutamatergic neuron with a soma found in cortical layer 5/6. http://purl.obolibrary.org/obo/UBERON_0007827 external nose http://purl.obolibrary.org/obo/UBERON_0034929 external soft tissue zone External part of the nose containing the external nares. http://purl.obolibrary.org/obo/CL_4030068 L6 intratelencephalic projecting Car3 glutamatergic neuron http://purl.obolibrary.org/obo/CL_4030065 L6 intratelencephalic projecting glutamatergic neuron A transcriptomically distinct intratelencepalic-projecting glutamatergic neuron that expresses Car3 with a soma found in L6. http://purl.obolibrary.org/obo/UBERON_0007828 girdle bone/zone http://purl.obolibrary.org/obo/UBERON_0010740 bone of appendage girdle complex A bone that is part of a appendage girdle region. http://purl.obolibrary.org/obo/UBERON_0007829 pectoral girdle bone http://purl.obolibrary.org/obo/UBERON_0010741 bone of pectoral complex A bone that is part of a pectoral girdle region. http://purl.obolibrary.org/obo/CL_4040005 mesenchymal stem cell of apical papilla http://purl.obolibrary.org/obo/CL_0000134 mesenchymal stem cell A mesenchymal stem cell that is part of the apical papilla tooth root. http://purl.obolibrary.org/obo/UBERON_0007830 pelvic girdle bone/zone http://purl.obolibrary.org/obo/UBERON_0010742 bone of pelvic complex A bone element or fused bone that is part of pelvic girdle. http://purl.obolibrary.org/obo/CL_4033061 endothelial cell of central vein of liver http://purl.obolibrary.org/obo/CL_0002543 vein endothelial cell An endothelial cell that is part of a central vein of liver. http://purl.obolibrary.org/obo/UBERON_0007832 pelvic girdle skeleton http://purl.obolibrary.org/obo/UBERON_0010719 girdle skeleton Skeletal subdivision consisting of a set of bones linking the axial series to the hindlimb zeugopodium and offering anchoring areas for hindlimb and caudal musculature. http://purl.obolibrary.org/obo/GO_0141124 intracellular signaling cassette http://purl.obolibrary.org/obo/GO_0035556 intracellular signal transduction An intracellular signaling module that is part of larger signaling pathways that can be initiated either intracellularly or by cell surface receptors. Intracellular signaling cassettes are discrete signaling units that are often shared by multiple signaling pathways. http://purl.obolibrary.org/obo/UBERON_0007842 membrane bone http://purl.obolibrary.org/obo/UBERON_0001474 bone element Bone element that arises as a result of intramembranous ossification. http://purl.obolibrary.org/obo/GO_0170033 L-amino acid metabolic process http://purl.obolibrary.org/obo/GO_1901605 alpha-amino acid metabolic process The chemical reactions and pathways involving an L-amino acid. http://purl.obolibrary.org/obo/UBERON_0007844 cartilage element http://purl.obolibrary.org/obo/UBERON_0004765 skeletal element Skeletal element that is composed of cartilage tissue and may be permanent or transient. http://purl.obolibrary.org/obo/GO_0170041 non-proteinogenic amino acid metabolic process http://purl.obolibrary.org/obo/GO_0006520 amino acid metabolic process The chemical reactions and pathways involving non-proteingenic amino acids. http://purl.obolibrary.org/obo/UBERON_0007845 regular connective tissue http://purl.obolibrary.org/obo/UBERON_0002384 connective tissue Connective tissue, which consists of fibroblasts, the intercellular matrix of which contains a regular network of collagen and elastic fiber bundles. Examples: bone (tissue), cartilage (tissue), dense regular connective tissue. http://purl.obolibrary.org/obo/GO_0170036 import into the mitochondrion http://purl.obolibrary.org/obo/GO_1990542 mitochondrial transmembrane transport The directed movement of substances from the cytosol into the mitochondrion. http://purl.obolibrary.org/obo/UBERON_0007846 dense regular connective tissue http://purl.obolibrary.org/obo/UBERON_0011823 dense connective tissue Connective tissue that is dominated by collagen fibres organized into a definitive pattern (e.g., parallel to one another), with comparatively fewer cells (mostly fibroblasts). http://purl.obolibrary.org/obo/GO_0170037 export from the mitochondrion http://purl.obolibrary.org/obo/GO_1990542 mitochondrial transmembrane transport The directed movement of substances from the mitochondrion to the cytosol. http://purl.obolibrary.org/obo/UBERON_0007914 bone of craniocervical region http://purl.obolibrary.org/obo/UBERON_0001474 bone element A bone that is part of a craniocervical region. http://purl.obolibrary.org/obo/UBERON_7770005 ascending colon epithelium http://purl.obolibrary.org/obo/UBERON_0000397 colonic epithelium An epithelial layer that lines the ascending colon. http://purl.obolibrary.org/obo/UBERON_7770006 transverse colon epithelium http://purl.obolibrary.org/obo/UBERON_0000397 colonic epithelium An epithelial layer that lines the transverse colon. http://purl.obolibrary.org/obo/UBERON_7770007 descending colon epithelium http://purl.obolibrary.org/obo/UBERON_0000397 colonic epithelium An epithelial layer that lines the descending colon. http://purl.obolibrary.org/obo/UBERON_7770008 sigmoid colon epithelium http://purl.obolibrary.org/obo/UBERON_0000397 colonic epithelium An epithelial layer that lines the sigmoid colon. http://purl.obolibrary.org/obo/UBERON_0007997 sesamoid bone of manus http://purl.obolibrary.org/obo/UBERON_0011141 appendicular ossicle A sesamoid bone that is part of a manus. http://purl.obolibrary.org/obo/UBERON_0008000 sesamoid bone of pes http://purl.obolibrary.org/obo/UBERON_0011141 appendicular ossicle A sesamoid bone that is part of a pes. http://purl.obolibrary.org/obo/UBERON_8600134 ascending colon lamina propria http://purl.obolibrary.org/obo/UBERON_0011189 lamina propria of large intestine The lamina propria that underlies the epithelial lining of the ascending colon. http://purl.obolibrary.org/obo/UBERON_0008001 irregular bone http://purl.obolibrary.org/obo/UBERON_0001474 bone element The irregular bones are bones which, from their peculiar form, cannot be grouped as long bone, short bone, flat bone or sesamoid bone. Irregular bones serve various purposes in the body, such as protection of nervous tissue, affording multiple anchor points for skeletal muscle attachment (as with the sacrum), and maintaining pharynx and trachea support, and tongue attachment (such as the hyoid bone). They consist of cancellous tissue enclosed within a thin layer of compact bone. The irregular bones are: the vertebrC&, sacrum, coccyx, temporal, sphenoid, ethmoid, zygomatic, maxilla, mandible, palatine, inferior nasal concha, and hyoid. http://purl.obolibrary.org/obo/UBERON_8600135 descending colon lamina propria http://purl.obolibrary.org/obo/UBERON_0011189 lamina propria of large intestine The lamina propria that underlies the epithelial lining of the descending colon. http://purl.obolibrary.org/obo/UBERON_0008114 joint of girdle http://purl.obolibrary.org/obo/UBERON_0000982 skeletal joint A skeletal joint that is part of a appendage girdle region. http://purl.obolibrary.org/obo/UBERON_8600136 sigmoid colon lamina propria http://purl.obolibrary.org/obo/UBERON_0011189 lamina propria of large intestine The lamina propria that underlies the epithelial lining of the sigmoid colon. http://purl.obolibrary.org/obo/UBERON_0008115 surface of cartilage http://purl.obolibrary.org/obo/UBERON_0036215 anatomical surface region An anatomical surface that is part of a cartilage element. http://purl.obolibrary.org/obo/UBERON_0008193 pneumatized bone http://purl.obolibrary.org/obo/UBERON_0001474 bone element A bone that is hollow or contains many air cells, such as the mastoid process of the temporal bone[TMD]. http://purl.obolibrary.org/obo/UBERON_8600137 transverse colon lamina propria http://purl.obolibrary.org/obo/UBERON_0011189 lamina propria of large intestine The lamina propria that underlies the epithelial lining of the transverse colon. http://purl.obolibrary.org/obo/UBERON_0008196 muscle of pectoral girdle http://purl.obolibrary.org/obo/UBERON_0010891 pectoral complex muscle Any muscle organ that is part of a pectoral girdle region. http://purl.obolibrary.org/obo/UBERON_8600139 caecum lamina propria http://purl.obolibrary.org/obo/UBERON_0011189 lamina propria of large intestine The lamina propria that underlies the epithelial lining of the caecum. http://purl.obolibrary.org/obo/UBERON_0008198 nail plate http://purl.obolibrary.org/obo/UBERON_0013754 integumentary system layer The nail plate is the hard and translucent portion of the nail, composed of keratin. http://purl.obolibrary.org/obo/UBERON_8600140 rectum lamina propria http://purl.obolibrary.org/obo/UBERON_0011189 lamina propria of large intestine The lamina propria that underlies the epithelial lining of the rectum. http://purl.obolibrary.org/obo/UBERON_0008203 pelvic cavity http://purl.obolibrary.org/obo/UBERON_0002553 anatomical cavity The part of the ventral body cavity that is within the pelvis. http://purl.obolibrary.org/obo/CL_4033103 superior cervical ganglion NPY neuron http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron A sympathetic neuron that has the soma located in the superior cervical ganglion and expresses the marker neuropeptide Y (NPY). http://purl.obolibrary.org/obo/UBERON_0008229 craniocervical region musculature http://purl.obolibrary.org/obo/UBERON_0001015 musculature Musculature system of the pharyngeal and head regions. http://purl.obolibrary.org/obo/CL_4301614 mature myelinating oligodendrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4300367 oligodendrocyte (Mmus) A mature myelinating oligodendrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Cldn11 (Mmus), Anln (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1184 MOL NN_4. http://purl.obolibrary.org/obo/UBERON_0008231 dorsal thoracic segment of trunk http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision Subdivision of thorax, which in humans is the posterior part of the thorax and is demarcated from the chest by the external surface of the posterolateral part of the rib cage and the anterior surface of the thoracic vertebral column; together with the chest, it constitutes the thorax. http://purl.obolibrary.org/obo/CL_4307084 CHOR NN_1 Tbc1d1 choroid plexus epithelial cell (Mmus) http://purl.obolibrary.org/obo/CL_4301608 choroid plexus epithelial cell (Mmus) A choroid plexus epithelial cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of 2900040C04Rik (Mmus), Tbc1d1 (Mmus). It is distinguished from other CHOR NN cells by expression of Tbc1d1. These cells are located in the Cerebellum, brain , in or close to the regions: Paraflocculus, choroid plexus . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5264 CHOR NN_1. http://purl.obolibrary.org/obo/UBERON_0008242 lower back muscle http://purl.obolibrary.org/obo/UBERON_0003833 abdominal segment muscle A muscle of back that is part of a lower back. http://purl.obolibrary.org/obo/CL_4304384 hypothalamic gonadotropin-releasing hormone neuron (Mmus) http://purl.obolibrary.org/obo/CL_0011111 hypothalamic gonadotropin-releasing hormone neuron A hypothalamic gonadotropin-releasing hormone neuron of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gnrh1 (Mmus). It is glutamatergic (inferred from expression of Gad1, Slc17a6, Gad2). These cells are located in the Hypothalamus, Olfactory areas, Pallidum, brain , in or close to the regions: Lateral septal nucleus, rostral (rostroventral) part, Medial septal nucleus, Diagonal band nucleus . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:2564 HY Gnrh1 Glut_1. http://purl.obolibrary.org/obo/UBERON_0008243 upper back muscle http://purl.obolibrary.org/obo/UBERON_0003830 thoracic segment muscle A muscle of back that is part of a dorsal thoracic segment of trunk. http://purl.obolibrary.org/obo/CL_4033151 nodose ganglion PVALB neuron http://purl.obolibrary.org/obo/CL_0000101 sensory neuron A sensory neuron that has the soma located in the nodose ganglion and expresses the marker parvalbumin (PVALB). http://purl.obolibrary.org/obo/UBERON_0008255 right clavicle http://purl.obolibrary.org/obo/UBERON_0001105 clavicle bone A clavicle that is in the right side of a entire appendicular skeleton. http://purl.obolibrary.org/obo/GO_0160275 negative regulation of white fat cell differentiation http://purl.obolibrary.org/obo/GO_0045599 negative regulation of fat cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of white fat cell differentiation. http://purl.obolibrary.org/obo/UBERON_0008256 left clavicle http://purl.obolibrary.org/obo/UBERON_0001105 clavicle bone A clavicle that is in the left side of a entire appendicular skeleton. http://purl.obolibrary.org/obo/CL_4307134 BAM NN_1 Fos border associated macrophage (Mmus) http://purl.obolibrary.org/obo/CL_4301625 border associated macrophage (Mmus) A border associated macrophage of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Mrc1 (Mmus), Pf4 (Mmus), Fos (Mmus). It is distinguished from other BAM NN cells by expression of Fos. These cells are located in the Isocortex, Cerebellum, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5314 BAM NN_1. http://purl.obolibrary.org/obo/UBERON_0008266 periodontal ligament http://purl.obolibrary.org/obo/UBERON_0010313 neural crest-derived structure The fibrous connective tissue that surrounds the root of a tooth, separating it from and attaching it to the alveolar bone. It extends from the base of the gingival mucosa to the fundus of the bony socket, and its main function is to hold the tooth in its socket[BTO]. http://purl.obolibrary.org/obo/CL_0008061 GABA-Chol neuron http://purl.obolibrary.org/obo/CL_0000617 GABAergic neuron A neuron that releases both gamma-aminobutyric acid and acetylcholine as vesicular neurotransmitters. Examples include some types of striatal interneuron. http://purl.obolibrary.org/obo/CL_0008059 GABA-Gly neuron http://purl.obolibrary.org/obo/CL_1001509 glycinergic neuron A neuron that releases both gamma-aminobutyric acid and glycine as vesicular neurotransmitters. Examples include types of amacrine cell and types of cerebellar inhibitory neurons. http://purl.obolibrary.org/obo/UBERON_0008281 tooth bud http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure A knoblike tooth primordium that develops into the mature tooth and consists of enamel organ, dental papilla, and dental sac enclosing them. http://purl.obolibrary.org/obo/CL_4307090 OPC NN_1 Rmi2 oligodendrocyte precursor cell (Mmus) http://purl.obolibrary.org/obo/CL_4300366 oligodendrocyte precursor cell (Mmus) A oligodendrocyte precursor cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Pdgfra (Mmus), Olig1 (Mmus), Rmi2 (Mmus), Col27a1 (Mmus). It is distinguished from other OPC NN_1 cells by expression of Rmi2, Col27a1. These cells are located in the Hypothalamus, Midbrain, Pallidum, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5270 OPC NN_1. http://purl.obolibrary.org/obo/UBERON_0008304 inner chondrogenic layer of perichondrium http://purl.obolibrary.org/obo/UBERON_0002384 connective tissue The perichondrium consists of two separate layers: an outer fibrous layer and inner chondrogenic layer. The chondrogenic layer remains undifferentiated and can form chondroblasts or chondrocytes. http://purl.obolibrary.org/obo/CL_4307005 CB PLI GABA Ly6d Purkinje layer interneuron http://purl.obolibrary.org/obo/CL_4300349 Purkinje layer interneuron (Mmus) A Purkinje layer interneuron of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Ly6d (Mmus), Kit (Mmus). It is distinguished from other CB PLI Gly-Gaba cells by expression of Ly6d. It is GABAergic (inferred from expression of Gad1, Gad2, Slc32a1). These cells are located in the Cerebellum, brain , in or close to the regions: arbor vitae, Interposed nucleus, Nodulus (X) . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5185 CB PLI Gly-Gaba_4. http://purl.obolibrary.org/obo/UBERON_0008305 outer fibrous layer of perichondrium http://purl.obolibrary.org/obo/UBERON_0002384 connective tissue The perichondrium consists of two separate layers: an outer fibrous layer and inner chondrogenic layer. The fibrous layer contains fibroblasts, which produce collagenous fibers. http://purl.obolibrary.org/obo/CL_4307042 Astro-TE NN_2 Clstn2 astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301592 Astro-TE NN_2 astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gm6145 (Mmus), E330013P04Rik (Mmus), Slc39a12 (Mmus). It is distinguished from other Astro-TE NN_2 cells by expression of Clstn2. These cells are located in the Hippocampal region , in or close to the regions: Dentate gyrus, molecular layer, Dentate gyrus, polymorph layer, Field CA3, stratum oriens, Dentate gyrus, granule cell layer . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5222 Astro-TE NN_2. http://purl.obolibrary.org/obo/UBERON_0008307 heart endothelium http://purl.obolibrary.org/obo/UBERON_0004852 cardiovascular system endothelium An endothelium that is part of a heart [Automatically generated definition]. http://purl.obolibrary.org/obo/CL_4300354 cerebellar granule cell (Mmus) http://purl.obolibrary.org/obo/CL_4300029 cerebellar glutamatergic neuron (Mmus) A cerebellar granule cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gabra6 (Mmus), Ror1 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Subclass:314 CB Granule Glut. http://purl.obolibrary.org/obo/UBERON_0008310 nasopharyngeal gland http://purl.obolibrary.org/obo/UBERON_0003295 pharyngeal gland A gland that is part of a nasopharynx. http://purl.obolibrary.org/obo/CL_4307026 Bergmann glial cell (Mmus) http://purl.obolibrary.org/obo/CL_0000644 Bergmann glial cell A Bergmann glial cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gpr37l1 (Mmus), Ctxn3 (Mmus). It is distinguished from other Astro-Epen cells by expression of Gpr37l1, Ctxn3. These cells are located in the Cerebellum, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5206 Bergmann NN_1. http://purl.obolibrary.org/obo/UBERON_0008324 erectile tissue http://purl.obolibrary.org/obo/UBERON_0000479 tissue With numerous vascular spaces that may become engorged with blood. http://purl.obolibrary.org/obo/CL_4307012 CBX MLI Cdh22 Gaba molecular layer interneuron (Mmus) http://purl.obolibrary.org/obo/CL_4300028 cerebellar GABAergic neuron (Mmus) A molecular layer interneuron of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Cdh1 (Mmus), Acvr1c (Mmus), Adamts15 (Mmus), Pax2 (Mmus). It is distinguished from other CB GABA cells by expression of Cdh1, Acvr1c, Adamts15, Pax2. It is GABAergic (inferred from expression of Gad1, Gad2, Slc32a1). These cells are located in the Cerebellum, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5192 CBX MLI Cdh22 Gaba_1. http://purl.obolibrary.org/obo/UBERON_0008331 clitoral smooth muscle http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure A smooth muscle tissue that is part of a clitoris. http://purl.obolibrary.org/obo/CL_4300358 subcortical astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_0000127 astrocyte A transcriptomically defined type of astrocyte located predominantly in the ventral and posterior subcortical areas. It is distinguished from other cells in the brain by selective expression of Aqp4 (Mmus), Cd38 (Mmus), Agt (Mmus), Itih3 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Subclass:318 Astro-NT NN. http://purl.obolibrary.org/obo/UBERON_0008338 plantar part of pes http://purl.obolibrary.org/obo/UBERON_0008837 palmar/plantar part of autopod The sole is the bottom of the foot. http://purl.obolibrary.org/obo/CL_4033156 jugular ganglion SPARCL1 neuron http://purl.obolibrary.org/obo/CL_0000101 sensory neuron A sensory neuron that has the soma located in the jugular ganglion and expresses the marker SPARC-like protein 1 (SPARCL1). http://purl.obolibrary.org/obo/UBERON_0008342 intestinal villus of duodenum http://purl.obolibrary.org/obo/UBERON_0001213 intestinal villus An intestinal villus in the duodenum. http://purl.obolibrary.org/obo/UBERON_0008343 intestinal villus of jejunum http://purl.obolibrary.org/obo/UBERON_0001213 intestinal villus An intestinal villus in the jejunum. http://purl.obolibrary.org/obo/CL_4072002 myelin-forming oligodendrocyte http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure A postmitotic and differentiated oligodendrocyte derived from a oligodendrocyte progenitor cell. A myelin-forming oligodendrocyte begins the expression of myelin genes and actively engages in the myelination process. In mice and humans, it is characterized by the upregulation of the key myelin-associated markers Mbp and Opalin. Additionally, Ctps (CTP synthase) shows peak expression at this stage, suggesting a heightened demand for nucleotide biosynthesis during membrane expansion and myelin production. http://purl.obolibrary.org/obo/UBERON_0008344 intestinal villus of ileum http://purl.obolibrary.org/obo/UBERON_0001213 intestinal villus An intestinal villus in the ileum. http://purl.obolibrary.org/obo/GO_0098690 glycinergic synapse http://purl.obolibrary.org/obo/GO_0045202 synapse A synapse that uses glycine as a neurotransmitter. http://purl.obolibrary.org/obo/UBERON_0008345 ileal epithelium http://purl.obolibrary.org/obo/UBERON_0013636 epithelium of intestinal villus An epithelium that is part of a ileum. http://purl.obolibrary.org/obo/GO_0120032 regulation of plasma membrane bounded cell projection assembly http://purl.obolibrary.org/obo/GO_0120035 regulation of plasma membrane bounded cell projection organization Any process that modulates the rate, frequency, or extent of plasma membrane bounded cell projection assembly. http://purl.obolibrary.org/obo/UBERON_0008346 duodenal epithelium http://purl.obolibrary.org/obo/UBERON_0013636 epithelium of intestinal villus An epithelium that is part of a duodenum. http://purl.obolibrary.org/obo/GO_0120033 negative regulation of plasma membrane bounded cell projection assembly http://purl.obolibrary.org/obo/GO_0120032 regulation of plasma membrane bounded cell projection assembly Any process that stops, prevents or reduces the frequency, rate or extent of plasma membrane bounded cell projection assembly. http://purl.obolibrary.org/obo/UBERON_0008367 breast epithelium http://purl.obolibrary.org/obo/UBERON_0000483 epithelium An epithelium that is part of a breast. http://purl.obolibrary.org/obo/GO_0120034 positive regulation of plasma membrane bounded cell projection assembly http://purl.obolibrary.org/obo/GO_0120032 regulation of plasma membrane bounded cell projection assembly Any process that activates or increases the frequency, rate or extent of plasma membrane bounded cell projection assembly. http://purl.obolibrary.org/obo/UBERON_0008397 tracheobronchial epithelium http://purl.obolibrary.org/obo/UBERON_0004815 lower respiratory tract epithelium Epithelium pertaining to the trachea and bronchi. http://purl.obolibrary.org/obo/GO_0061868 hepatic stellate cell migration http://purl.obolibrary.org/obo/GO_0010761 fibroblast migration The orderly movement of a hepatic stellate cell from one site to another. http://purl.obolibrary.org/obo/UBERON_0008404 proximal tubular epithelium http://purl.obolibrary.org/obo/UBERON_0004810 nephron tubule epithelium The cells lining the proximal tubule are cuboidal epithelial cells with deep basal membrane invaginations that provide a large basal surface area. The long microvilli (the brush border) lining the tubule lumen, maximize luminal surface area and make these cells ideally suited for both reabsorptive and secretory functions. http://purl.obolibrary.org/obo/GO_0061869 regulation of hepatic stellate cell migration http://purl.obolibrary.org/obo/GO_0010762 regulation of fibroblast migration Any process that modulates the frequency, rate or extent of hepatic stellate cell migration. http://purl.obolibrary.org/obo/UBERON_0008408 distal tubular epithelium http://purl.obolibrary.org/obo/UBERON_0004810 nephron tubule epithelium An epithelium that is part of a distal tubule. http://purl.obolibrary.org/obo/GO_0061870 positive regulation of hepatic stellate cell migration http://purl.obolibrary.org/obo/GO_0061869 regulation of hepatic stellate cell migration Any process that increases the frequency, rate or extent of hepatic stellate cell migration. http://purl.obolibrary.org/obo/UBERON_0008425 mammary ridge http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure A ridge of epidermal cells that will form the mammary placodes. http://purl.obolibrary.org/obo/GO_0061871 negative regulation of hepatic stellate cell migration http://purl.obolibrary.org/obo/GO_0061869 regulation of hepatic stellate cell migration Any process that stops, prevents or reduces the frequency, rate or extent of hepatic stellate cell migration. http://purl.obolibrary.org/obo/GO_0140131 positive regulation of lymphocyte chemotaxis http://purl.obolibrary.org/obo/GO_1901623 regulation of lymphocyte chemotaxis Any process that activates or increases the frequency, rate or extent of lymphocyte chemotaxis. http://purl.obolibrary.org/obo/UBERON_0008429 cervical vertebral foramen http://purl.obolibrary.org/obo/UBERON_0005744 bone foramen A vertebral foramen that is part of a cervical vertebra. http://purl.obolibrary.org/obo/UBERON_0036264 zygomaticotemporal nerve http://purl.obolibrary.org/obo/UBERON_0011779 nerve of head region The zygomaticotemporal nerve or zygomaticotemporal branch (temporal branch) is derived from the maxillary branch of the trigeminal nerve (Cranial nerve V). It runs along the lateral wall of the orbit in a groove in the zygomatic bone, receives a branch of communication from the lacrimal, and passes through zygomaticotemporal foramen in the zygomatic bone to enter the temporal fossa. It ascends between the bone, and substance of the Temporalis muscle, pierces the temporal fascia about 2.5 cm. above the zygomatic arch, and is distributed to the skin of the side of the forehead, and communicates with the facial nerve and with the auriculotemporal branch of the mandibular nerve. As it pierces the temporal fascia, it gives off a slender twig, which runs between the two layers of the fascia to the lateral angle of the orbit. http://purl.obolibrary.org/obo/UBERON_0008430 lumbar vertebral foramen http://purl.obolibrary.org/obo/UBERON_0005744 bone foramen A vertebral foramen that is part of a lumbar vertebra. http://purl.obolibrary.org/obo/GO_0140227 serotonin-gated cation-selective signaling pathway http://purl.obolibrary.org/obo/GO_1990806 ligand-gated ion channel signaling pathway The series of molecular signals initiated by serotonin binding to a seratonin receptor on the surface of the target cell, followed by the movement of ions through a channel in the receptor complex. Ends with regulation of a downstream cellular process, e.g. transcription. http://purl.obolibrary.org/obo/UBERON_0008431 sacral foramen http://purl.obolibrary.org/obo/UBERON_0005744 bone foramen A vertebral foramen that is part of a sacral vertebra. http://purl.obolibrary.org/obo/STATO_0000416 precision http://purl.obolibrary.org/obo/STATO_0000607 proportion precision or positive predictive value is defined as the proportion of the true positives against all the positive results (both true positives and false positives) A proportion in which the numerator represents the correctly detected items within the denominator that represents all items detected. http://purl.obolibrary.org/obo/UBERON_0008432 thoracic vertebral foramen http://purl.obolibrary.org/obo/UBERON_0005744 bone foramen A vertebral foramen that is part of a thoracic vertebra. http://purl.obolibrary.org/obo/GO_0140318 protein transporter activity http://purl.obolibrary.org/obo/GO_0005215 transporter activity Directly binding to a specific protein and delivering it to a specific cellular location. http://purl.obolibrary.org/obo/UBERON_0008433 lumbar vertebral arch http://purl.obolibrary.org/obo/UBERON_0004247 bone of dorsum A neural arch that is part of a lumbar vertebra. http://purl.obolibrary.org/obo/GO_0110141 L-glutamate import into mitochondrion http://purl.obolibrary.org/obo/GO_0015813 L-glutamate transmembrane transport The process in which L-glutamate is transported from the cytosol into the mitochondrial matrix. http://purl.obolibrary.org/obo/UBERON_0008434 cervical vertebral arch http://purl.obolibrary.org/obo/UBERON_0004247 bone of dorsum A neural arch that is part of a cervical vertebra. http://purl.obolibrary.org/obo/GO_0150102 negative regulation of monocyte activation http://purl.obolibrary.org/obo/GO_0002695 negative regulation of leukocyte activation Any process that stops, prevents or reduces the frequency, rate or extent of monocyte activation. http://purl.obolibrary.org/obo/UBERON_0008435 vertebral arch of sacral segment http://purl.obolibrary.org/obo/UBERON_0005179 pelvic region element A neural arch that is part of a sacral vertebra. http://purl.obolibrary.org/obo/CL_0011013 motile sperm cell http://purl.obolibrary.org/obo/CL_0000219 motile cell A sperm cell that is cabaple of motion (motility). http://purl.obolibrary.org/obo/UBERON_0008436 thoracic vertebral arch http://purl.obolibrary.org/obo/UBERON_0004247 bone of dorsum A neural arch that is part of a thoracic vertebra. http://purl.obolibrary.org/obo/UBERON_0008447 intertarsal joint http://purl.obolibrary.org/obo/UBERON_0001487 pes joint Intertarsal articulations are the joints of the tarsus. The specific intertarsal articulations are: Talocalcaneal articulation Talocalcaneonavicular articulation Calcaneocuboid articulation Cuneonavicular articulation Cuboideonavicular articulation Intercuneiform articulation Cuneocuboid articulation. http://purl.obolibrary.org/obo/CL_0011014 non-motile sperm cell http://purl.obolibrary.org/obo/CL_0000019 sperm A sperm cell that is not cabaple of motion (motility). http://purl.obolibrary.org/obo/UBERON_0008522 nasal muscle http://purl.obolibrary.org/obo/UBERON_0001577 facial muscle Any muscle organ that is part of an nose. http://purl.obolibrary.org/obo/CL_0011015 amoeboid sperm cell http://purl.obolibrary.org/obo/CL_0011013 motile sperm cell A motile sperm cell that contain no F-actin, and their motility is powered by a dynamic filament system. http://purl.obolibrary.org/obo/UBERON_0008715 muscle tissue of prostate http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure A muscle tissue that is part of a prostate gland. http://purl.obolibrary.org/obo/CL_0011016 flagellated sperm cell http://purl.obolibrary.org/obo/CL_0011013 motile sperm cell A motile sperm cell that contains a slender threadlike microscopic appendage that enables motion. http://purl.obolibrary.org/obo/UBERON_0008772 proximal epiphysis of tibia http://purl.obolibrary.org/obo/UBERON_0004383 epiphysis of tibia A proximal epiphysis that is part of a tibia. http://purl.obolibrary.org/obo/CL_0011018 lymphoid tissue–inducer cell http://purl.obolibrary.org/obo/CL_0001071 group 3 innate lymphoid cell A group 3 innate lymphoid cell that express ROR gamma t and IL-7R alpha in the absence of lineage markers (e.g. CD3, CD19, B220, CD11c, Gr-1), with the functional ability to interact with mesenchymal cells through lymphotoxin and tumor necrosis factor. Lymphoid tissue-inducer cells are key to the development of lymph nodes and Peyer’s patches. http://purl.obolibrary.org/obo/UBERON_0008775 proximal epiphysis of fibula http://purl.obolibrary.org/obo/UBERON_0004388 epiphysis of fibula A proximal epiphysis that is part of a fibula. http://purl.obolibrary.org/obo/GO_0120222 regulation of blastocyst development http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of blastocyst development. http://purl.obolibrary.org/obo/UBERON_8000006 left side of back http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure Left part of the organism dorsal to a horizontal plane and bounded on one side by the same transverse plane. http://purl.obolibrary.org/obo/UBERON_8000007 right side of back http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure Right part of the organism dorsal to a horizontal plane and bounded on one side by the same transverse plane. http://purl.obolibrary.org/obo/UBERON_8300000 skin of scalp http://purl.obolibrary.org/obo/UBERON_0001084 skin of head A zone of skin that is part of a scalp. http://purl.obolibrary.org/obo/UBERON_0008780 inner cell mass derived epiblast http://purl.obolibrary.org/obo/UBERON_0002532 epiblast (generic) An embryonic structure that is derived from the inner cell mass and lies above the hypoblast and gives rise to the three primary germ layers. http://purl.obolibrary.org/obo/UBERON_8300001 right forelimb http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure A forelimb that is on the right side of a pectoral complex. http://purl.obolibrary.org/obo/UBERON_0008783 dorsal venous arch http://purl.obolibrary.org/obo/UBERON_0001638 vein The dorsal venous arch of the foot is a superficial vein that connects the small saphenous vein and the great saphenous vein. Anatomically, it is defined by where the dorsal veins of the first and fifth digit, respectively, meet the great saphenous vein and small saphenous vein. http://purl.obolibrary.org/obo/UBERON_8300002 left forelimb http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure A forelimb that is on the left side of a pectoral complex. http://purl.obolibrary.org/obo/UBERON_0008784 lower limb segment http://purl.obolibrary.org/obo/UBERON_0002529 limb segment A limb segment that is part of a hindlimb. http://purl.obolibrary.org/obo/UBERON_8300003 right hindlimb http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure A hindlimb that is on the right side of a pelvic complex. http://purl.obolibrary.org/obo/UBERON_0008785 upper limb segment http://purl.obolibrary.org/obo/UBERON_0002529 limb segment A limb segment that is part of a forelimb. http://purl.obolibrary.org/obo/UBERON_8300004 left hindlimb http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure A hindlimb that is on the left side of a pelvic complex. http://purl.obolibrary.org/obo/PATO_0070020 stellate pyramidal morphology http://purl.obolibrary.org/obo/PATO_0070017 standard pyramidal morphology A pyramidal cell morphology that inheres in neurons which lack a tuft formation but extend to small radial distances forming a star-like shape. http://purl.obolibrary.org/obo/UBERON_0008789 cranial fossa http://purl.obolibrary.org/obo/UBERON_0004704 bone fossa Any of the three large depressions in the posterior, middle, and anterior aspects of the floor of the cranial cavity. http://purl.obolibrary.org/obo/CL_4023094 tufted pyramidal neuron http://purl.obolibrary.org/obo/CL_0000598 pyramidal neuron A pyramidal neuron which has a distinctive tuft formation, distal from the soma. http://purl.obolibrary.org/obo/UBERON_0008803 skin of cheek http://purl.obolibrary.org/obo/UBERON_1000021 skin of face A zone of skin that is part of a cheek. http://purl.obolibrary.org/obo/UBERON_8410001 small intestine venule http://purl.obolibrary.org/obo/UBERON_0001979 venule Venule of villus of small intestine. http://purl.obolibrary.org/obo/UBERON_0008805 gingival groove http://purl.obolibrary.org/obo/UBERON_0000093 sulcus The gingival sulcus is an area of potential space between a tooth and the surrounding gingival tissue and is lined by sulcular epithelium. The depth of the sulcus (Latin for groove) is bounded by two entities: apically by the gingival fibers of the connective tissue attachment and coronally by the free gingival margin. http://purl.obolibrary.org/obo/UBERON_8410002 small intestine lymphatic vessel http://purl.obolibrary.org/obo/UBERON_0001473 lymphatic vessel A lymphatic vessel that supplies the small intestine. http://purl.obolibrary.org/obo/UBERON_0008811 intromittent organ http://purl.obolibrary.org/obo/UBERON_0003135 male reproductive organ An external organ of a male organism that is specialized to deliver sperm during copulation. Intromittent organs are found most often in terrestrial species, as most aquatic species fertilize their eggs externally, although there are exceptions[WP]. http://purl.obolibrary.org/obo/UBERON_8410004 small intestine arteriole http://purl.obolibrary.org/obo/UBERON_0001980 arteriole Arteriole of villus of small intestine. http://purl.obolibrary.org/obo/UBERON_0008814 pharyngeal arch system http://purl.obolibrary.org/obo/UBERON_0034921 multi organ part structure A transient embryonic complex that comprises the pharyngeal arches, bulges of tissues of mesoderm and neural crest derivation through which pass nerves and pharyngeal arch arteries. The arches are separated internally by pharyngeal pouches, evaginations of foregut endoderm, and externally by pharyngeal clefts, invaginations of surface ectoderm. The development of the system ends when the stucture it contributes to are forming, which may include (depending on species) the thymus, thyroid, parathyroids, maxilla, mandible, aortic arch, cardiac outflow tract, external and middle ear[GO,modified]. http://purl.obolibrary.org/obo/UBERON_8410008 venule of anorectum http://purl.obolibrary.org/obo/UBERON_0001979 venule A venule that is located in the anorectum. http://purl.obolibrary.org/obo/UBERON_0008816 embryonic head http://purl.obolibrary.org/obo/UBERON_0000033 head A head that is part of a embryo. http://purl.obolibrary.org/obo/UBERON_8410009 arteriole of anorectum http://purl.obolibrary.org/obo/UBERON_0001980 arteriole An arteriole that is located in the anorectum. http://purl.obolibrary.org/obo/UBERON_0008817 thymus primordium endoderm http://purl.obolibrary.org/obo/UBERON_0000925 endoderm An endoderm that is part of a thymus primordium. http://purl.obolibrary.org/obo/UBERON_8410015 arteriole of colon http://purl.obolibrary.org/obo/UBERON_0001980 arteriole An arteriole located in the colon. http://purl.obolibrary.org/obo/UBERON_0008823 neural tube derived brain http://purl.obolibrary.org/obo/UBERON_0000489 cavitated compound organ A brain that develops_from a neural tube. http://purl.obolibrary.org/obo/UBERON_8410032 trabecular sinus of lymph node http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space The trabecular sinus is the lymph-filled space outside the trabeculae between lobules of the lymph node. This is a continuation of the subcapsular sinus which receives the afferent vessels and is present beneath the capsule. This space is traversed by both reticular fibers and cells in the lymph. http://purl.obolibrary.org/obo/UBERON_0008824 duct of epididymis http://purl.obolibrary.org/obo/UBERON_0005904 duct of male reproductive system Any duct branching of of the main epididymis duct. http://purl.obolibrary.org/obo/UBERON_8410035 medullary arteriole of lymph node http://purl.obolibrary.org/obo/UBERON_8410042 arteriole of lymph node An arteriole that arises from the hilar artery of a lymph node and radiates centrifugally, branching in the medulla. http://purl.obolibrary.org/obo/UBERON_8410036 medullary venule of lymph node http://purl.obolibrary.org/obo/UBERON_8410041 venule of lymph node Medullary venules are a continuation of high endothelial venules which condense repeatedly in the interfollicular cortex and peripheral deep cortical unit and then transition to medullary venules at the corticomedullary junction. The medullary venules condense and return centripetally to the hilar vein. http://purl.obolibrary.org/obo/UBERON_0008826 pulmonary surfactant http://purl.obolibrary.org/obo/UBERON_0006538 respiratory system fluid/secretion A substance formed by type II alveolar cells composed of surface-active lipoprotein complex (phospholipoprotein). http://purl.obolibrary.org/obo/UBERON_8410041 venule of lymph node http://purl.obolibrary.org/obo/UBERON_0001979 venule A venule that is part of a lymph node. http://purl.obolibrary.org/obo/UBERON_0008835 hepatic diverticulum http://purl.obolibrary.org/obo/UBERON_0009854 digestive tract diverticulum An out-pocket of thickened ventral foregut epithelium adjacent to the developing heart. Constitutes the first morphological sign of the embryonic liver. The anterior portion of the hepatic diverticulum gives rise to the liver and intrahepatic biliary tree, while the posterior portion forms the gall bladder and extrahepatic bile ducts. http://purl.obolibrary.org/obo/UBERON_8410042 arteriole of lymph node http://purl.obolibrary.org/obo/UBERON_0001980 arteriole An arteriole that is part of a lymph node. http://purl.obolibrary.org/obo/UBERON_0008845 nonskeletal ligament http://purl.obolibrary.org/obo/UBERON_0000211 ligament A ligament that does not connect two skeletal elements. http://purl.obolibrary.org/obo/UBERON_8410043 bronchus submucosal gland http://purl.obolibrary.org/obo/UBERON_8410077 airway submucosal gland A submucosal gland located in a bronchus. http://purl.obolibrary.org/obo/UBERON_0008846 skeletal ligament http://purl.obolibrary.org/obo/UBERON_0000211 ligament Dense regular connective tissue connecting two or more adjacent skeletal elements[VSAO,modified]. http://purl.obolibrary.org/obo/UBERON_8410048 venule of colon http://purl.obolibrary.org/obo/UBERON_0001979 venule A venule located in the colon. http://purl.obolibrary.org/obo/UBERON_0008851 ectoplacental cavity http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space Closed space within the ectoplacental cone, formed by the fusion of the parts of the amniotic fold that separate it from the amniotic cavity[MP]. a developmental cavity that exists in some mammals and is derived by division of the proamniotic space; it is further removed from the embryo than the amniotic cavity in some mammals. http://purl.obolibrary.org/obo/UBERON_8410050 anorectum http://purl.obolibrary.org/obo/UBERON_0004921 subdivision of digestive tract A subdivision of the digestive tract in humans that includes the rectum, the anal canal and the anus. http://purl.obolibrary.org/obo/UBERON_0008856 stomach muscularis externa http://purl.obolibrary.org/obo/UBERON_0034933 layer of smooth muscle tissue The smooth muscle layer of the stomach wall that functions to churn and mix food and gastric secretions as well as to move food along the digestive tract to the intestines. http://purl.obolibrary.org/obo/UBERON_8410051 lymphatic vessel of colon http://purl.obolibrary.org/obo/UBERON_0001473 lymphatic vessel A lymphatic vessel located in the colon. http://purl.obolibrary.org/obo/UBERON_0008857 stomach smooth muscle circular layer http://purl.obolibrary.org/obo/UBERON_0012368 circular muscle layer of muscular coat The middle layer of the muscularis; it is continuous with the circular layer of the esophagus, but is absent in the fundus and lies concentric to the longitudinal axis of the stomach; the circular layer is normally tonically constricted forming a functional pyloric sphincter, which controls the movement of chyme into the duodenum. http://purl.obolibrary.org/obo/UBERON_8410056 capillary of anorectum http://purl.obolibrary.org/obo/UBERON_0001982 capillary A capillary that is part of the anorectum. http://purl.obolibrary.org/obo/UBERON_0008858 pyloric canal http://purl.obolibrary.org/obo/UBERON_0009870 zone of stomach The short narrow part of the stomach extending from the pyloric antrum to the pyloric sphincter. http://purl.obolibrary.org/obo/UBERON_8410057 capillary of colon http://purl.obolibrary.org/obo/UBERON_0001982 capillary A capillary that is part of the colon. http://purl.obolibrary.org/obo/UBERON_0008859 cardiac gastric gland http://purl.obolibrary.org/obo/UBERON_0000414 mucous gland A gastric gland in the cardiac region of the stomach; cardiac glands are fewer in number than in the fundus and body, and secrete mucin which coats the stomach and protects it[MP]. http://purl.obolibrary.org/obo/PATO_0070027 bitufted dendrite cell morphology http://purl.obolibrary.org/obo/PATO_0010006 cell morphology A cell morphology that inheres in neurons with dendrites that are bidirectional, emerging from opposite ends of the soma, with the two arbors extending in radial or tangential directions. http://purl.obolibrary.org/obo/UBERON_0008861 pyloric gastric gland http://purl.obolibrary.org/obo/UBERON_0000414 mucous gland The gastric glands in the pyloric region of the stomach; the pyloric glands secrete mucin, which coats the stomach and protects it, and hormones such as gastrin and enkephalin[MP]. http://purl.obolibrary.org/obo/GO_0140694 membraneless organelle assembly http://purl.obolibrary.org/obo/GO_0070925 organelle assembly The aggregation, arrangement and bonding together of a set of components to form a non-membrane-bounded organelle. http://purl.obolibrary.org/obo/UBERON_0008862 stomach smooth muscle inner oblique layer http://purl.obolibrary.org/obo/UBERON_0034933 layer of smooth muscle tissue The innermost layer of the muscularis; it is not present in all sections of the stomach but is clearly seen in the fundus and near the lesser curvature of the corpus; the oblique fibers disappear distally (towards the pyloric antrum); the oblique layer is responsible for creating the motion that churns and physically breaks down the food. http://purl.obolibrary.org/obo/CL_0009006 enteroendocrine cell of small intestine http://purl.obolibrary.org/obo/CL_1001598 small intestine secretory cell An enteroendocrine cell that is located in the small intestine. http://purl.obolibrary.org/obo/UBERON_0008870 pulmonary alveolar parenchyma http://purl.obolibrary.org/obo/UBERON_0008946 lung parenchyma The distinguishing cell types of the lung alveolar tissue, including pulmonary epithelial cells (pneumocytes), alveolar capillary endothelial cells, interstitial cells (fibroblasts) and alveolar macrophages. http://purl.obolibrary.org/obo/CL_0009037 lymph node mantle zone B cell http://purl.obolibrary.org/obo/CL_0000236 B cell A B lymphocyte that resides in the mantle zone of the lymph node germinal center. These are generally IgM and IgD positive activated B cells that form a 'corona' around the germinal center and are part of the establishment of a secondary lymphatic follicule. http://purl.obolibrary.org/obo/UBERON_0008874 pulmonary acinus http://purl.obolibrary.org/obo/UBERON_0001062 anatomical entity The largest lung subunit in which all airways participate in gas exchange, and it is composed of the parenchyma of the respiratory bronchioles, alveolar ducts, and alveoli. http://purl.obolibrary.org/obo/CL_0009040 stromal cell of lamina propria of colon http://purl.obolibrary.org/obo/CL_0009021 stromal cell of lamina propria of large intestine A stromal cell found in the lamina propria of the colon. http://purl.obolibrary.org/obo/UBERON_0008876 hypodermis skeletal muscle layer http://purl.obolibrary.org/obo/UBERON_0014892 skeletal muscle organ, vertebrate Any skeletal muscle organ in the hypodermis / superficial fascia. http://purl.obolibrary.org/obo/CL_0009041 tuft cell of colon http://purl.obolibrary.org/obo/CL_0011108 colon epithelial cell A tuft cell that is part of the colonic epithelium, primarily adapted for microbial sensing in the dense colonic microbiota. Unlike its small intestinal counterpart, it does not participate in parasite-driven tuft cell–ILC2 circuits. Instead, it detects bacterial metabolites via taste-signaling pathways (Strine and Craig, 2022). The colonic tuft cell plays a key role in epithelial repair, modulates inflammatory responses through IL-25 secretion, and contributes to intestinal homeostasis by balancing microbiome interactions (Sebastian et al., 2021). http://purl.obolibrary.org/obo/UBERON_0008877 epidermal-dermal junction http://purl.obolibrary.org/obo/UBERON_0005769 basement membrane of epithelium The multi-layer basement membrane between the dermis and epidermis that serves to adhere the dermis and epidermis, provide mechanical support for the epidermis, and forms a barrier to cells and large molecules across the junction. http://purl.obolibrary.org/obo/CL_0009042 enteroendocrine cell of colon http://purl.obolibrary.org/obo/CL_1001516 intestinal enteroendocrine cell An enteroendocrine cell that is located in the colon. http://purl.obolibrary.org/obo/UBERON_0008882 spinal cord commissure http://purl.obolibrary.org/obo/UBERON_0007699 tract of spinal cord The nerve fiber tracts that span the midline of the spinal cord. http://purl.obolibrary.org/obo/CL_0009043 intestinal crypt stem cell of colon http://purl.obolibrary.org/obo/CL_0009016 intestinal crypt stem cell of large intestine An intestinal crypt stem cell that is located in the crypt of Lieberkuhn of colon. http://purl.obolibrary.org/obo/UBERON_0008884 left putamen http://purl.obolibrary.org/obo/UBERON_0001874 putamen A putamen that is part of a left cerebral hemisphere. http://purl.obolibrary.org/obo/CL_0009044 lymphocyte of small intestine lamina propria http://purl.obolibrary.org/obo/CL_0000542 lymphocyte A lymphocyte that resides in the lamina propria of the small intestine. Lamina propria leukocytes and intraepithelial lymphocytes are the effector compartments of the gut mucosal immune system. Lymphocytes circulate through gut associated lymphoid tissues until recruitment by intestinal antigens. They are involved in the gut immune response. http://purl.obolibrary.org/obo/UBERON_0008885 right putamen http://purl.obolibrary.org/obo/UBERON_0001874 putamen A putamen that is part of a right cerebral hemisphere. http://purl.obolibrary.org/obo/CL_0009049 smooth muscle cell of high endothelial venule of lymph node http://purl.obolibrary.org/obo/CL_0008035 microcirculation associated smooth muscle cell A layer of smooth muscle cells that forms the outer layer of the high endothelial venule of lymph node and pumps to allow flow of lymph fluid carrying lymphocytes. http://purl.obolibrary.org/obo/UBERON_0008886 pulmonary vascular system http://purl.obolibrary.org/obo/UBERON_0007798 vascular system The part of the cardiovascular system consisting of all pulmonary arteries and all pulmonary veins. http://purl.obolibrary.org/obo/CL_0009062 germinal center T cell http://purl.obolibrary.org/obo/CL_0002038 T follicular helper cell A specialized type of CD4 positive T cell, the follicular helper T cell (TFH cell), that upregulates CXCR5 expression to enable its follicular localization. These specialised T cells reside in the germinal center of the lymph node. http://purl.obolibrary.org/obo/UBERON_0008887 rectal venous plexus http://purl.obolibrary.org/obo/UBERON_0001593 venous plexus The hemorrhoidal plexus (or rectal venous plexus) surrounds the rectum, and communicates in front with the vesical venous plexus in the male, and the uterovaginal plexus in the female. A free communication between the portal and systemic venous systems is established through the hemorrhoidal plexus. http://purl.obolibrary.org/obo/CL_0009064 lymph node paracortex T cell http://purl.obolibrary.org/obo/CL_0000084 T cell A T cell located in the lymph node paracortex, where macrophages and dendritic cells present antigenic peptides to these naïve T cells, stimulating them to become activated helper T cells or cytotoxic T lymphocytes. http://purl.obolibrary.org/obo/UBERON_0008895 splanchnocranium http://purl.obolibrary.org/obo/UBERON_0011159 primary subdivision of cranial skeletal system Subdivision of endoskeleton derived from pharyngeal arches. http://purl.obolibrary.org/obo/CL_0009067 vacuolated fetal-type enterocyte http://purl.obolibrary.org/obo/CL_0002254 epithelial cell of small intestine An enterocyte found in the small intestine of newborn mammals and characterized by the presence of an apical canalicular system (ACS) leading to production of large vacuoles, important for colostral macromolecule uptake. After birth, the vacuolated fetal-type enterocytes are replaced with enterocytes lacking an ACS. http://purl.obolibrary.org/obo/CL_0009068 CD8aa(I) thymocyte http://purl.obolibrary.org/obo/CL_0000893 thymocyte An unconventional T lymphocyte population within the thymic medulla that is potentially a thymic resident population. http://purl.obolibrary.org/obo/UBERON_0008896 post-hyoid pharyngeal arch http://purl.obolibrary.org/obo/UBERON_0002539 pharyngeal arch A pharyngeal arch that is posterior to the hyoid arch. i.e. any pharyngeal arch with a number 3 or higher. http://purl.obolibrary.org/obo/CL_0009069 CD8aa(II) thymocyte http://purl.obolibrary.org/obo/CL_0000893 thymocyte An unconventional T lymphocyte population within the thymic medulla that expresses both alpha/beta and gamma/delta T cell signatures. http://purl.obolibrary.org/obo/UBERON_0008904 neuromast http://purl.obolibrary.org/obo/UBERON_0035555 lateral line sense organ Volcano-shaped lateral line sensory organ located in characteristic positions within the skin epithelium and containing hair cells and their support elements. http://purl.obolibrary.org/obo/UBERON_0008906 lateral line nerve http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure Cranial nerves that carry afferent and efferent fibers for the lateral line system. http://purl.obolibrary.org/obo/CL_0009070 corticomedullary thymic epithelial cell http://purl.obolibrary.org/obo/CL_0002293 epithelial cell of thymus A thymic epithelial cell located at the corticomedullary junction. http://purl.obolibrary.org/obo/UBERON_0008907 dermal bone http://purl.obolibrary.org/obo/UBERON_0007842 membrane bone Skeletal element that forms superficially in the organism, usually in association with the ectoderm[VSAO]. http://purl.obolibrary.org/obo/UBERON_0008909 perichordal bone http://purl.obolibrary.org/obo/UBERON_0012075 replacement bone Bone element that is adjacent to the notochord. http://purl.obolibrary.org/obo/CL_0009071 medullary thymic epithelial cell type 1 http://purl.obolibrary.org/obo/CL_0002365 medullary thymic epithelial cell A thymic medullary epithelial cell considered to be a pre-AIRE mTEC population. http://purl.obolibrary.org/obo/CL_0009072 medullary thymic epithelial cell type 2 http://purl.obolibrary.org/obo/CL_0002365 medullary thymic epithelial cell A thymic medullary epithelial cell that expresses AIRE or other canonical markers of mature mTECs like Fezf2. http://purl.obolibrary.org/obo/UBERON_0008921 substratum of layer of retina http://purl.obolibrary.org/obo/UBERON_0022303 nervous system cell part layer Missing definition for term UBERON:0008921. Please replace it using linked reference. http://purl.obolibrary.org/obo/UBERON_0008922 sublaminar layer S1 http://purl.obolibrary.org/obo/UBERON_0009735 sublaminar layers S1 or S3 or S4 A retinal neural layer that is immediately adjacent to the inner nuclear layer and comprises 20 percent of the inner plexiform layer of retina. http://purl.obolibrary.org/obo/CL_0009073 medullary thymic epithelial cell type 3 http://purl.obolibrary.org/obo/CL_0002365 medullary thymic epithelial cell A thymic medullary epithelial cell considered to be a post-AIRE cell. This group of AIRE-mTECs is heterogeneous and also includes mTECs within Hassall's Corpuscles. http://purl.obolibrary.org/obo/UBERON_0008923 sublaminar layer S2 http://purl.obolibrary.org/obo/UBERON_0008928 sublaminar layers S2 or S3 A retinal neural layer that is immediately adjacent to the S1 and S3 layers and comprises 20 percent of the inner plexiform layer of retina. http://purl.obolibrary.org/obo/CL_0009074 medullary thymic epithelial cell type 4 http://purl.obolibrary.org/obo/CL_0002365 medullary thymic epithelial cell A thymic medullary epithelial cell that expresses typical tuft cell markers instead of classical mTEC or cTEC markers. This population has a bulbous-like structure. http://purl.obolibrary.org/obo/CL_0009075 myo-medullary thymic epithelial cell http://purl.obolibrary.org/obo/CL_0002365 medullary thymic epithelial cell A thymic medullary epithelial cell that expresses muscle-specific biomarkers. http://purl.obolibrary.org/obo/UBERON_0008924 sublaminar layer S3 http://purl.obolibrary.org/obo/UBERON_0009731 sublaminar layers S3 or S4 A retinal neural layer that is immediately adjacent to the S2 and S4 layers and comprises 20 percent of the inner plexiform layer of retina. http://purl.obolibrary.org/obo/CL_0009076 neuro-medullary thymic epithelial cell http://purl.obolibrary.org/obo/CL_0002365 medullary thymic epithelial cell A thymic medullary epithelial cell that expresses neuroendocrine biomarkers. http://purl.obolibrary.org/obo/UBERON_0008925 sublaminar layer S4 http://purl.obolibrary.org/obo/UBERON_0009731 sublaminar layers S3 or S4 A retinal neural layer that is immediately adjacent to the S3 and S5 layer and comprises 20 percent of the inner plexiform layer of retina. http://purl.obolibrary.org/obo/CL_0009077 subcapsular thymic epithelial cell http://purl.obolibrary.org/obo/CL_0002364 cortical thymic epithelial cell A thymic epithelial cell located within the subcapsular region of the thymus. http://purl.obolibrary.org/obo/UBERON_0008926 sublaminar layer S5 http://purl.obolibrary.org/obo/UBERON_0009732 sublaminar layers S1 or S2 or S5 A retinal neural layer that is immediately adjacent to the retinal ganglion cell layer and comprises 20 percent of the ganglion plexiform layer of retina. http://purl.obolibrary.org/obo/CL_0009078 thymic fibroblast type 1 http://purl.obolibrary.org/obo/CL_4030001 stromal cell of thymus A fibroblast located in the thymic capsule. http://purl.obolibrary.org/obo/UBERON_0008927 sublaminar layers S1 or S2 http://purl.obolibrary.org/obo/UBERON_0009733 sublaminar layers S1 or S2 or S3 One of sublaminar layers S1 or S2. http://purl.obolibrary.org/obo/CL_0009079 thymic fibroblast type 2 http://purl.obolibrary.org/obo/CL_4030001 stromal cell of thymus A fibroblast located between thymic lobules. http://purl.obolibrary.org/obo/UBERON_0008928 sublaminar layers S2 or S3 http://purl.obolibrary.org/obo/UBERON_0009734 sublaminar layers S2 or S3 or S4 One of sublaminar layers S2 or S3. http://purl.obolibrary.org/obo/CL_0009080 tuft cell of small intestine http://purl.obolibrary.org/obo/CL_0002254 epithelial cell of small intestine A tuft cell located in the small intestine. http://purl.obolibrary.org/obo/UBERON_0008929 sublaminar layers S4 or S5 http://purl.obolibrary.org/obo/UBERON_0009736 sublaminar layers S3 or S4 or S5 One of sublaminar layers S4 or S5. http://purl.obolibrary.org/obo/CL_0009081 specified double negative thymocyte (Homo sapiens) http://purl.obolibrary.org/obo/CL_0002489 double negative thymocyte The human equivalent of a DN2 thymocyte; typically contains two phases, in the latter of which these thymocytes begin the process of beta selection. http://purl.obolibrary.org/obo/UBERON_0008946 lung parenchyma http://purl.obolibrary.org/obo/UBERON_0000353 parenchyma A parenchyma that is part of a lung. http://purl.obolibrary.org/obo/UBERON_0008951 left lung lobe http://purl.obolibrary.org/obo/UBERON_0000101 lobe of lung A lobe of lung that is part of a left lung. http://purl.obolibrary.org/obo/CL_0009082 committed double negative thymocyte (Homo sapiens) http://purl.obolibrary.org/obo/CL_0002489 double negative thymocyte The human equivalent of a DN3 thymocyte; these thymocytes finish the process of beta selection. http://purl.obolibrary.org/obo/UBERON_0008962 forelimb bone http://purl.obolibrary.org/obo/UBERON_0015021 forelimb endochondral element A bone that is part of a forelimb region. Examples: humerus, any of the phalanges. Counter-example: scapula (a bone of the pectoral girdle). Note that we consider the forelimb to end at the shoulder. http://purl.obolibrary.org/obo/CL_0009083 rearranging double negative thymocyte (Homo sapiens) http://purl.obolibrary.org/obo/CL_0002489 double negative thymocyte The human equivalent of a DN4 thymocyte. http://purl.obolibrary.org/obo/UBERON_0008969 dental follicle http://purl.obolibrary.org/obo/UBERON_0010371 ecto-epithelium A sac containing the developing tooth and its odontogenic organ. The dental follicle (DF) differentiates into the periodontal ligament. In addition, it may be the precursor of other cells of the periodontium, including osteoblasts, cementoblasts and fibroblasts. They develop into the alveolar bone, the cementum with Sharpey's fibers and the periodontal ligament fibers respectively. http://purl.obolibrary.org/obo/CL_0011031 monocyte-derived dendritic cell http://purl.obolibrary.org/obo/CL_0000782 myeloid dendritic cell A dendritic cell that develops from a monocyte. http://purl.obolibrary.org/obo/CL_0011032 lysosome-rich enterocyte http://purl.obolibrary.org/obo/CL_0000584 enterocyte An enterocyte that possesses a large supranuclear vacuolar system that preferentially internalizes dietary protein via receptor-mediated and fluid-phase endocytosis for intracellular digestion and trans-cellular transport. In zebrafish these cells are located in the posterior region of the mid intestine throughout life. In mammals they are found in the ileum pre-weaning and later are replaced by mature enterocytes. http://purl.obolibrary.org/obo/UBERON_0008982 fascia http://purl.obolibrary.org/obo/UBERON_0007846 dense regular connective tissue A dense regular connective tissue that that connects muscles together[WP, modified]. http://purl.obolibrary.org/obo/UBERON_0008987 renal parenchyma http://purl.obolibrary.org/obo/UBERON_0000353 parenchyma The functional tissue of the kidney, consisting of the nephrons. http://purl.obolibrary.org/obo/CL_4023020 dynamic gamma motor neuron http://purl.obolibrary.org/obo/CL_0008037 gamma motor neuron A gamma motor neuron that innervates dynamic nuclear bag fibers (bag1 fibers) and enhances the sensitivities of Ia sensory neurons. They alter muscle spindle sensitivity and increases its discharge in response to velocity of muscle length (rather than just magnitude). http://purl.obolibrary.org/obo/UBERON_0008989 submucosal esophageal gland http://purl.obolibrary.org/obo/UBERON_0011148 submucosal gland One of the racemose glands in the walls of the esophagus that in humans are small and serve principally to lubricate the food but in some birds secrete a milky fluid on which the young are fed. http://purl.obolibrary.org/obo/CL_4023021 static gamma motor neuron http://purl.obolibrary.org/obo/CL_0008037 gamma motor neuron A gamma motor neuron that innervates static nuclear bag fibers (bag2 fibers) and increases their firing, in response to an increase in the magnitude of change in length, and controls the static sensitivity of the stretch reflex. http://purl.obolibrary.org/obo/UBERON_0008995 nucleus of cerebellar nuclear complex http://purl.obolibrary.org/obo/UBERON_0009662 hindbrain nucleus Four accumulations of gray substance embedded in the white substance of the cerebellum, comprising the nucleus dentatus, nucleus emboliformis, nucleus globosus, and nucleus fastigii. http://purl.obolibrary.org/obo/CL_4023097 arachnoid barrier cell http://purl.obolibrary.org/obo/CL_4023058 mesothelial fibroblast of the leptomeninx A mesothelial fibroblast of the arachnoid barrier layer. Arachnoid barrier cells make up the tight-junctioned layer in the leptomeninx that functions as the physiologic barrier between the cerebrospinal fluid in the subarachnoid space and the fenestrated capillaries in the dura. http://purl.obolibrary.org/obo/UBERON_0008998 vasculature of brain http://purl.obolibrary.org/obo/UBERON_0036303 vasculature of central nervous system System pertaining to blood vessels in the brain. http://purl.obolibrary.org/obo/CL_4023108 oxytocin-secreting magnocellular cell http://purl.obolibrary.org/obo/CL_0011003 magnocellular neurosecretory cell A magnocellular neurosecretory cell that is capable of producing and secreting oxytocin. http://purl.obolibrary.org/obo/UBERON_0009010 periurethral tissue http://purl.obolibrary.org/obo/UBERON_0000479 tissue Any portion of tissue that surrounds a urethra. http://purl.obolibrary.org/obo/CL_4023109 vasopressin-secreting magnocellular cell http://purl.obolibrary.org/obo/CL_0011003 magnocellular neurosecretory cell A magnocellular neurosecretory cell that is capable of producing and secreting vasopressin. http://purl.obolibrary.org/obo/UBERON_0009014 lower back skin http://purl.obolibrary.org/obo/UBERON_0003836 abdominal segment skin A zone of skin that is part of a lower back. http://purl.obolibrary.org/obo/UBERON_0009015 upper back skin http://purl.obolibrary.org/obo/UBERON_0001418 skin of thorax A zone of skin that is part of a dorsal thoracic segment of trunk. http://purl.obolibrary.org/obo/CL_4023110 amygdala pyramidal neuron http://purl.obolibrary.org/obo/CL_0012001 neuron of the forebrain A pyramidal neuron with soma located in the amygdala. http://purl.obolibrary.org/obo/CL_4023111 cerebral cortex pyramidal neuron http://purl.obolibrary.org/obo/CL_0010012 cerebral cortex neuron A pyramidal neuron with soma located in the cerebral cortex. http://purl.obolibrary.org/obo/UBERON_0009027 vesical artery http://purl.obolibrary.org/obo/UBERON_0001637 artery An artery that supplies blood to the urinary bladder. http://purl.obolibrary.org/obo/UBERON_0009029 pudendal vein http://purl.obolibrary.org/obo/UBERON_0003520 pelvis blood vessel Either the internal or external pudendal vein, running from the genital-vulvar area and abdomen and down the leg. http://purl.obolibrary.org/obo/CL_4023112 vestibular afferent neuron http://purl.obolibrary.org/obo/CL_0000101 sensory neuron An afferent neuron of the vestibular system that innervate the base of the hair cell and increase or decrease their neural firing rate as the receptor cell is excited or inhibited. http://purl.obolibrary.org/obo/UBERON_0009030 left pulmonary vein http://purl.obolibrary.org/obo/UBERON_0002016 pulmonary vein Vein that drains left lung and returns blood to the heart. http://purl.obolibrary.org/obo/CL_4023113 bouton vestibular afferent neuron http://purl.obolibrary.org/obo/CL_4023112 vestibular afferent neuron A vestibular afferent neuron that makes bouton synapses to type II hair cells. http://purl.obolibrary.org/obo/UBERON_0009032 right pulmonary vein http://purl.obolibrary.org/obo/UBERON_0002016 pulmonary vein Vein that drains right lung and returns blood to the heart. http://purl.obolibrary.org/obo/CL_4023114 calyx vestibular afferent neuron http://purl.obolibrary.org/obo/CL_4023112 vestibular afferent neuron A vestibular afferent neuron which posseses a unique postsynaptic terminal, the calyx, which completely covers the basolateral walls of type I hair cells and receives input from multiple ribbon synapses. http://purl.obolibrary.org/obo/UBERON_0009035 renal straight tubule http://purl.obolibrary.org/obo/UBERON_0007685 region of nephron tubule Any region of a nephron tubule that is straight. Examples: distal convoluted tubule, proximal convoluted tuble. http://purl.obolibrary.org/obo/CL_4023115 type 1 spiral ganglion neuron http://purl.obolibrary.org/obo/UBERON_0000122 neuron projection bundle A spiral ganglion neuron that innervates inner hair cells. Type 1 spiral ganglion neurons are myelinated and bipolar. http://purl.obolibrary.org/obo/UBERON_0009039 lymph node germinal center http://purl.obolibrary.org/obo/UBERON_0010754 germinal center A germinal center that is located in a lymph node. http://purl.obolibrary.org/obo/CL_4023116 type 2 spiral ganglion neuron http://purl.obolibrary.org/obo/UBERON_0000122 neuron projection bundle A spiral ganglion neuron that innervates outer hair cells. Type 1 spiral ganglion neurons are unmyelinated and unipolar. http://purl.obolibrary.org/obo/UBERON_0009042 prostatic venous plexus http://purl.obolibrary.org/obo/UBERON_0006876 vasculature of organ The prostatic veins form a well-marked prostatic plexus which lies partly in the fascial sheath of the prostate and partly between the sheath and the prostatic capsule. It communicates with the pudendal and vesical plexuses. http://purl.obolibrary.org/obo/CL_4023118 L5/6 non-Martinotti sst GABAergic interneuron (Mmus) http://purl.obolibrary.org/obo/CL_0010011 cerebral cortex GABAergic interneuron A sst GABAergic interneuron does not have Martinotti morphology with a soma found in L5/6 of the cerebral cortex. http://purl.obolibrary.org/obo/UBERON_0009097 gravid organism http://purl.obolibrary.org/obo/UBERON_0007023 adult organism An organism containing a developing embryo, fetus, or unborn offspring within the body. http://purl.obolibrary.org/obo/CL_4023119 displaced amacrine cell http://purl.obolibrary.org/obo/CL_0000561 amacrine cell A subpopulation of amacrine cell that migrate further than other amacrine cells, and come to lie basal to the inner plexiform layer (IPL) in the ganglion cell layer. Displaced amacrine cells still have their neurites extending apically into the IPL, and therefore exhibit an inverted polarity with respect to the other amacrine cells. http://purl.obolibrary.org/obo/UBERON_0009098 gravid uterus http://purl.obolibrary.org/obo/UBERON_0000995 uterus The uterus in pregnancy. http://purl.obolibrary.org/obo/CL_4023120 cochlea auditory hair cell http://purl.obolibrary.org/obo/CL_0002374 ear hair cell An auditory hair cell found in the cochlea. http://purl.obolibrary.org/obo/UBERON_0009114 cervical thymus http://purl.obolibrary.org/obo/UBERON_0002370 thymus A mature thymus that is entirely part of the cervical region. http://purl.obolibrary.org/obo/UBERON_8410038 high endothelial venule of lymph node http://purl.obolibrary.org/obo/UBERON_8410041 venule of lymph node A high endothelial venule that is part of a of lymph node. http://purl.obolibrary.org/obo/UBERON_0009115 thoracic thymus http://purl.obolibrary.org/obo/UBERON_0005178 thoracic cavity element A mature thymus that is entirely part of thoracic region. http://purl.obolibrary.org/obo/UBERON_8410065 lymph node follicle marginal zone http://purl.obolibrary.org/obo/UBERON_0001744 lymphoid tissue Histologically, the marginal zone pattern of the lymph node is characterized by lymphoid follicles with three distinct layers. The inner layer is composed of follicular center zones, the middle layer of darkly stained mantle zones, and the outer layer of marginal zones. However, the marginal zone pattern is rarely seen in reactive lymph nodes except for mesenteric lymph nodes. Lymph node marginal zones are populated by marginal zone B cells which express CD19 and CD20 and have the phenotypic features of memory B cells. http://purl.obolibrary.org/obo/UBERON_0009117 indifferent gonad http://purl.obolibrary.org/obo/UBERON_0000991 gonad A gonad prior to differentiating into a definitive testis or ovary. http://purl.obolibrary.org/obo/UBERON_8410066 lymph node paracortex http://purl.obolibrary.org/obo/UBERON_0001744 lymphoid tissue The lymph node paracortex is the middle layer of the lymph node and is mostly populated by T cells and dendritic cells. The paracortex also contains specialised blood vessels called high endothelial venules which allow lymphocytes to enter the node. http://purl.obolibrary.org/obo/UBERON_0009122 adenohypophyseal placode http://purl.obolibrary.org/obo/UBERON_0011814 non-neurogenic ectodermal placode The adenohypophyseal placode forms the anterior lobe of the pituitary gland and gives rise to the endocrine secretory cells of the pituitary. http://purl.obolibrary.org/obo/UBERON_8440000 cortical layer II/III http://purl.obolibrary.org/obo/UBERON_8440004 laminar subdivision of the cortex A laminar subdivision of the neocortex that is comprised of a part of layer II and a part of layer III. http://purl.obolibrary.org/obo/UBERON_0009124 geniculate placode http://purl.obolibrary.org/obo/UBERON_0003078 epibranchial placode Rostralmost epibranchial placode. Associated with 1st branchial cleft. http://purl.obolibrary.org/obo/UBERON_8440001 cortical layer IV/V http://purl.obolibrary.org/obo/UBERON_8440004 laminar subdivision of the cortex A laminar subdivision of the neocortex that is comprised of a part of layer IV and a part of layer V. http://purl.obolibrary.org/obo/UBERON_0009125 petrosal placode http://purl.obolibrary.org/obo/UBERON_0003078 epibranchial placode Epibranchial placode between geniculate and nodose. Associated with 2nd branchial cleft. http://purl.obolibrary.org/obo/UBERON_8440002 cortical layer V/VI http://purl.obolibrary.org/obo/UBERON_8440004 laminar subdivision of the cortex A laminar subdivision of the neocortex that is comprised of a part of layer V and a part of layer VI. http://purl.obolibrary.org/obo/UBERON_0009126 nodosal placode http://purl.obolibrary.org/obo/UBERON_0003078 epibranchial placode Caudalmost epibranchial placode. Associated with 3rd branchial cleft. http://purl.obolibrary.org/obo/UBERON_8440003 cortical layer VIb http://purl.obolibrary.org/obo/UBERON_0002301 layer of neocortex The deepest layer of the neocortex. While layer 6b is considered part of layer 6, it is distinct morphologically, genetically, and developmentally from the rest of layer 6. Neurons in L6b project to cortical targets and higher-order thalamus and develop from a precursor population that arises from the subplate. http://purl.obolibrary.org/obo/UBERON_0009127 epibranchial ganglion http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure Cranial ganglion which develops from an epibranchial placode. http://purl.obolibrary.org/obo/CL_0009089 lung pericyte http://purl.obolibrary.org/obo/CL_0000669 pericyte A pericyte cell that is part of a lung. http://purl.obolibrary.org/obo/UBERON_0009128 lateral line placode http://purl.obolibrary.org/obo/UBERON_0003067 dorsolateral placode An ectodermal placode that will develop into the components of the lateral line system. http://purl.obolibrary.org/obo/CL_0009096 esophagus non-keratinized squamous epithelial cell http://purl.obolibrary.org/obo/CL_0002252 epithelial cell of esophagus Any cell that is part of the esophageal non-keratinized stratified squamous epithelium. In humans, the esophagus, which requires flexibility to accommodate swallowing of a bolus, is covered with a non-keratinized epithelium. http://purl.obolibrary.org/obo/UBERON_0009129 right atrium endocardium http://purl.obolibrary.org/obo/UBERON_0002166 endocardium of atrium Endocardium that is part of the right atrium. http://purl.obolibrary.org/obo/CL_0009098 fetal and neonatal skeletal muscle fiber http://purl.obolibrary.org/obo/CL_0008002 skeletal muscle fiber A skeletal muscle fiber found at the fetal and neonatal stages. In mammalian fetuses and neonates, skeletal muscle expresses myosin heavy chain-neonatal (MyHC-neo, encoded by the MYH8 gene). This expression disappears shortly after birth and is replaced by expression of adult heavy chain myosins. http://purl.obolibrary.org/obo/UBERON_0009133 pleuroperitoneal membrane http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue A fold of tissue which extends into the peritoneal cavity of the developing embryo and participates in the separation of the pleural and peritoneal cavities. http://purl.obolibrary.org/obo/CL_0009110 lymphatic endothelial cell of medulla ceiling http://purl.obolibrary.org/obo/CL_0009115 lymph node lymphatic vessel endothelial cell A lymphatic endothelial cell located in the ceiling part of a lymph node medulla. http://purl.obolibrary.org/obo/UBERON_0009141 craniocervical region vein http://purl.obolibrary.org/obo/UBERON_0013140 systemic vein A vein that is part of a craniocervical region. http://purl.obolibrary.org/obo/CL_0009112 centroblast http://purl.obolibrary.org/obo/CL_0000844 germinal center B cell A germinal center B cell found in a lymph node germinal center dark zone. http://purl.obolibrary.org/obo/UBERON_0009142 entire embryonic mesenchyme http://purl.obolibrary.org/obo/UBERON_0000477 anatomical cluster Sum total of mesenchyme in the embryo. http://purl.obolibrary.org/obo/CL_4030017 epithelial cell of late distal convoluted tubule http://purl.obolibrary.org/obo/CL_1000849 kidney distal convoluted tubule epithelial cell An epithelial cell located in the late distal convoluted tubule. http://purl.obolibrary.org/obo/UBERON_0009191 sphenoid bone pre-cartilage condensation http://purl.obolibrary.org/obo/UBERON_0015060 sphenoid endochondral element A sphenoid endochondral element that is composed primarily of a pre-cartilage condensation. http://purl.obolibrary.org/obo/CL_4030016 epithelial cell of early distal convoluted tubule http://purl.obolibrary.org/obo/CL_1000849 kidney distal convoluted tubule epithelial cell An epithelial cell located in the early distal convoluted tubule. http://purl.obolibrary.org/obo/UBERON_0009193 sphenoid cartilage element http://purl.obolibrary.org/obo/UBERON_0015060 sphenoid endochondral element A sphenoid endochondral element that is composed primarily of cartilage tissue. http://purl.obolibrary.org/obo/UBERON_8450002 excretory system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system An anatomical system that eliminates waste products that arise as a result of metabolic activity. http://purl.obolibrary.org/obo/UBERON_0009198 craniofacial suture http://purl.obolibrary.org/obo/UBERON_0002209 fibrous joint Any suture between cranial and/or facial bones. http://purl.obolibrary.org/obo/CL_4032001 reelin GABAergic cortical interneuron http://purl.obolibrary.org/obo/CL_0010011 cerebral cortex GABAergic interneuron A GABAergic interneuron located in the cerebral cortex that expresses reelin (rln). http://purl.obolibrary.org/obo/UBERON_0009199 facial suture http://purl.obolibrary.org/obo/UBERON_0009198 craniofacial suture Any suture between facial bones. http://purl.obolibrary.org/obo/CL_0003045 M12 retinal ganglion cell http://purl.obolibrary.org/obo/CL_0003001 bistratified retinal ganglion cell A bistratified ganglion cell with larger, asymetric dendritic fields that terminate in S2 and S4. http://purl.obolibrary.org/obo/UBERON_0009200 limb epidermis http://purl.obolibrary.org/obo/UBERON_3000981 limb external integument structure The limb epidermis is the outer epithelial layer of the limb, it is a complex stratified squamous epithelium. http://purl.obolibrary.org/obo/CL_0003039 M8 retinal ganglion cell http://purl.obolibrary.org/obo/CL_0000740 retinal ganglion cell A monostratified retinal ganglion cell with large soma and medium dendritic field, with dense dendritic arbor. http://purl.obolibrary.org/obo/UBERON_0009201 nephric duct http://purl.obolibrary.org/obo/UBERON_0012275 meso-epithelium A nephric duct is a tube that drains a primitive kidney[GO]. http://purl.obolibrary.org/obo/CL_0003031 M3-ON retinal ganglion cell http://purl.obolibrary.org/obo/CL_4023032 ON retinal ganglion cell A monostratified retinal ganglion cell that has post synaptic terminals in sublaminar layer S4 and is depolarized by illumination of its receptive field center. http://purl.obolibrary.org/obo/UBERON_0009204 medial nasal process mesenchyme http://purl.obolibrary.org/obo/UBERON_0009501 mesenchyme of fronto-nasal process Mesenchyme that is part of a medial nasal prominence. http://purl.obolibrary.org/obo/CL_0003005 G4 retinal ganglion cell http://purl.obolibrary.org/obo/CL_0000740 retinal ganglion cell A mono-stratified retinal ganglion cell that has a small dendritic field and dense dendritic arbor. http://purl.obolibrary.org/obo/UBERON_0009205 lateral nasal process mesenchyme http://purl.obolibrary.org/obo/UBERON_0009501 mesenchyme of fronto-nasal process Mesenchyme that is part of a lateral nasal prominence. http://purl.obolibrary.org/obo/CL_0004139 retinal ganglion cell A2 outer http://purl.obolibrary.org/obo/CL_0004138 retinal ganglion cell A2 A retinal ganglion A2 cell with dendrites terminating in S2. http://purl.obolibrary.org/obo/UBERON_0009206 lateral nasal process surface ectoderm http://purl.obolibrary.org/obo/UBERON_0014702 frontonasal process epithelium An ectoderm that is part of a lateral nasal prominence. http://purl.obolibrary.org/obo/CL_0004124 retinal ganglion cell C1 http://purl.obolibrary.org/obo/CL_0003024 retinal ganglion cell C inner A retinal ganglion cell C inner that has medium dendritic diversity. http://purl.obolibrary.org/obo/UBERON_0009210 pharyngeal membrane http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure A thin fold of ectoderm and endoderm that separates the pharyngeal pouches from the pharyngeal clefts in a developing embryo. http://purl.obolibrary.org/obo/CL_0004235 AB broad diffuse-1 amacrine cell http://purl.obolibrary.org/obo/CL_0004252 medium field retinal amacrine cell An amacrine cell with a medium dendritic field and post-synaptic terminals in S2 and S3. This cell type releases the neurotransmitter gamma-aminobutyric acid (GABA). http://purl.obolibrary.org/obo/UBERON_0009213 pharyngeal membrane of 1st arch http://purl.obolibrary.org/obo/UBERON_0009210 pharyngeal membrane A pharyngeal membrane that separates the first pharyngeal cleft from the first pharyngeal pouch. http://purl.obolibrary.org/obo/CL_0004231 recurving diffuse amacrine cell http://purl.obolibrary.org/obo/CL_0004251 narrow field retinal amacrine cell A broadly stratifying amacrine cell with a small dendritic field and a complex dendritic arbor. Recurving diffuse amacrine cells have post-synaptic terminals in S2, S3, and S4. http://purl.obolibrary.org/obo/UBERON_0009291 cartilaginous vertebral centrum http://purl.obolibrary.org/obo/UBERON_0016491 vertebral centrum element Cartilaginous form of a vertebral centrum, a skeletal element that functionally replaces the notochord[VSAP,modified]. http://purl.obolibrary.org/obo/CL_0003024 retinal ganglion cell C inner http://purl.obolibrary.org/obo/CL_0004116 retinal ganglion cell C A retinal ganglion cell C with medium cell bodies and large dendritic field. http://purl.obolibrary.org/obo/UBERON_0009471 dorsum of tongue http://purl.obolibrary.org/obo/UBERON_0000064 organ part The superior surface of the tongue divided by the sulcus terminalis into an anterior two-thirds, the presulcal part (pars presulcalis). and a posterior one-third, the postsulcal part (pars postsulcalis). http://purl.obolibrary.org/obo/UBERON_8480029 skin of external genitalia http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure A zone of skin that is part of the external genitalia. http://purl.obolibrary.org/obo/UBERON_0009472 axilla http://purl.obolibrary.org/obo/UBERON_0034929 external soft tissue zone The axilla is the area directly under the joint where the forelimb connects to the shoulder. http://purl.obolibrary.org/obo/CL_4033038 lung resident memory CD4-positive, alpha-beta T cell http://purl.obolibrary.org/obo/CL_0000897 CD4-positive, alpha-beta memory T cell An alpha-beta CD4 T cell that resides in the lung. http://purl.obolibrary.org/obo/UBERON_0009477 associated mesenchyme of otic placode http://purl.obolibrary.org/obo/UBERON_0007213 mesenchyme derived from head neural crest Mesenchyme that is part of a otic placode. http://purl.obolibrary.org/obo/CL_4033039 lung resident memory CD8-positive, alpha-beta T cell http://purl.obolibrary.org/obo/CL_0000909 CD8-positive, alpha-beta memory T cell An alpha-beta CD8 T cell that resides in the lung. http://purl.obolibrary.org/obo/UBERON_0009479 ectoderm of buccopharyngeal membrane http://purl.obolibrary.org/obo/UBERON_0000924 ectoderm An ectoderm that is part of a buccopharyngeal membrane. http://purl.obolibrary.org/obo/CL_4033049 taste receptor cell of tongue http://purl.obolibrary.org/obo/CL_0002319 neural cell A taste receptor cell that is part of a taste bud of a tongue. http://purl.obolibrary.org/obo/UBERON_0009480 endoderm of buccopharyngeal membrane http://purl.obolibrary.org/obo/UBERON_0000925 endoderm An endoderm that is part of a buccopharyngeal membrane. http://purl.obolibrary.org/obo/CL_4033050 catecholaminergic neuron http://purl.obolibrary.org/obo/CL_0000540 neuron A neuron that releases catecholamine as a neurotransmitter. http://purl.obolibrary.org/obo/UBERON_0009482 associated mesenchyme of foregut-midgut junction http://purl.obolibrary.org/obo/UBERON_0003104 mesenchyme Mesenchyme that is part of a foregut-midgut junction. http://purl.obolibrary.org/obo/UBERON_8600010 bronchial submucosal gland ciliated duct http://purl.obolibrary.org/obo/UBERON_8600014 submucosal gland ciliated duct A ciliated duct part of a bronchial submucosal gland. http://purl.obolibrary.org/obo/UBERON_0009483 mesentery of foregut-midgut junction http://purl.obolibrary.org/obo/UBERON_0002095 mesentery A mesentery that is part of a foregut-midgut junction. http://purl.obolibrary.org/obo/UBERON_8600011 tracheal submucosal gland ciliated duct http://purl.obolibrary.org/obo/UBERON_8600014 submucosal gland ciliated duct A ciliated duct part of a tracheal submucosal gland. http://purl.obolibrary.org/obo/UBERON_0009494 pharyngeal arch mesenchymal region http://purl.obolibrary.org/obo/UBERON_0007524 dense mesenchyme tissue A portion of mesenchymal tissue associated with an individual pharyngeal arch. http://purl.obolibrary.org/obo/UBERON_8600012 submucosal gland acinus http://purl.obolibrary.org/obo/UBERON_0014717 mucous acinus A spherical or tubular structure in a submucosal gland that produces and secretes mucus and other substances into the ducts leading to the surface epithelium. http://purl.obolibrary.org/obo/UBERON_0009497 epithelium of foregut-midgut junction http://purl.obolibrary.org/obo/UBERON_0005911 endo-epithelium An epithelium that is part of a foregut-midgut junction. http://purl.obolibrary.org/obo/UBERON_8600014 submucosal gland ciliated duct http://purl.obolibrary.org/obo/UBERON_0000058 duct A ciliated tubular structure in a submucosal gland connecting the submucosal gland collecting duct with the surface epithelium. http://purl.obolibrary.org/obo/UBERON_0009500 periotic mesenchyme http://purl.obolibrary.org/obo/UBERON_0007213 mesenchyme derived from head neural crest Anatomical region that surrounds the otic vesicle. http://purl.obolibrary.org/obo/GO_0160307 protein biosynthetic process http://purl.obolibrary.org/obo/GO_0009059 macromolecule biosynthetic process The chemical reactions and pathways resulting in the formation of protein. http://purl.obolibrary.org/obo/UBERON_0009501 mesenchyme of fronto-nasal process http://purl.obolibrary.org/obo/UBERON_0007213 mesenchyme derived from head neural crest The embryonic connective tissue made up of loosely aggregated mesenchymal cells, supported by interlaminar jelly, that gives rise to the frontonasal region of the head. http://purl.obolibrary.org/obo/GO_0180064 protein O-linked glycosylation via xylose http://purl.obolibrary.org/obo/GO_0006493 protein O-linked glycosylation A glycoprotein biosynthetic process starting with the covalent linkage of a xylose via a beta-glycosidic bond to the oxygen atom of a serine or a threonine side chain in a protein, which can be further elongated with the sequential addition of sugar units resulting in the formation of a protein O-linked glycan. http://purl.obolibrary.org/obo/UBERON_0009503 mesenchyme of hindgut http://purl.obolibrary.org/obo/UBERON_0003104 mesenchyme Mesenchyme that is part of a developing hindgut. http://purl.obolibrary.org/obo/CL_4052061 epidermal keratinocyte http://purl.obolibrary.org/obo/CL_0000362 epidermal cell A keratinocyte of the skin epidermis that synthesizes keratin and undergoes successive stages of differentiation as it migrates from the basal layer to the cornified (stratum corneum) layer. These differentiation stages include the basal, spinous (prickle), and granular cell layers. This cell is central to epidermal homeostasis, mediating wound healing, immune modulation, including the secretion of cytokines and chemokines that recruit neutrophils (Simmons and Gallo, 2024), and intercellular communication with adjacent melanocytes (Marrapodi and Bellei, 2024). http://purl.obolibrary.org/obo/UBERON_0009505 mesenchyme of trachea http://purl.obolibrary.org/obo/UBERON_0007524 dense mesenchyme tissue Mesenchyme that is part of a developing trachea. http://purl.obolibrary.org/obo/CL_4052058 Merkel cell of epidermis http://purl.obolibrary.org/obo/CL_0000362 epidermal cell A Merkel cell found mainly in the basal layer of the epidermis and the outer root sheath of hair follicles, particularly concentrated in areas with high tactile acuity, such as touch domes, hair follicles, and fingertips. http://purl.obolibrary.org/obo/UBERON_0009506 mesenchyme of middle ear http://purl.obolibrary.org/obo/UBERON_0007524 dense mesenchyme tissue Mesenchyme that is part of a developing middle ear. http://purl.obolibrary.org/obo/UBERON_8600148 tooth surface structure http://purl.obolibrary.org/obo/UBERON_0003102 surface structure A surface structure that is part of a calcareous tooth. http://purl.obolibrary.org/obo/UBERON_0009521 anal membrane endodermal component http://purl.obolibrary.org/obo/UBERON_0005911 endo-epithelium An endoderm that is part of a anal region. http://purl.obolibrary.org/obo/CL_4033097 Schlemm's canal endothelial cell http://purl.obolibrary.org/obo/CL_0002543 vein endothelial cell A specialised endothelial cell that is part of the canal of Schlemm. This cell type shares characteristics and expresses markers of both blood and lymphatic endothelial cells (Kizhatil et al., 2014) and regulates aqueous humor outflow resistance by modulating pore formation and responding to mechanical strain (Stamer et al., 2015). http://purl.obolibrary.org/obo/UBERON_0009522 lateral lingual swelling epithelium http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue An epithelium that is part of a lateral lingual swelling. http://purl.obolibrary.org/obo/CL_4072001 newly formed oligodendrocyte http://purl.obolibrary.org/obo/CL_0000128 oligodendrocyte A post-mitotic oligodendrocyte that has exited the cell cycle and begun early stage differentiation. The cell begins to acquire oligodendrocyte-like characteristics but has not yet initiated myelination. In mice, NFOL is marked by the expression of Tcf7l2 and Cemip2 (also known as Tmem2), among other early myelin-related genes. These markers highlight cells transitioning from a precursor to a more differentiated, pre-myelinating state. http://purl.obolibrary.org/obo/UBERON_0009523 mesenchyme of handplate http://purl.obolibrary.org/obo/UBERON_0010377 mesenchyme from somatopleure Mesenchyme that is part of a handplate. http://purl.obolibrary.org/obo/CL_4300029 cerebellar glutamatergic neuron (Mmus) http://purl.obolibrary.org/obo/CL_2000028 cerebellum glutamatergic neuron A cerebellum glutamatergic neuron of the Mus musculus brain. Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Class:29 CB Glut. http://purl.obolibrary.org/obo/UBERON_0009526 maxillary process mesenchyme http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue Mesenchyme that is part of a maxillary prominence. http://purl.obolibrary.org/obo/CL_4300031 OPC-Oligo cell (Mmus) http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell A cell of the Mus musculus brain. Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Class:31 OPC-Oligo. http://purl.obolibrary.org/obo/UBERON_0009536 vascular element of left lung http://purl.obolibrary.org/obo/UBERON_0005629 vascular plexus A vascular plexus that is part of a left lung. http://purl.obolibrary.org/obo/CL_4300359 astrocyte of cerebrum (Mmus) http://purl.obolibrary.org/obo/CL_0000127 astrocyte A transcritpomically defined type of astrocytes primarily restricted to the dorsal regions of the cerebrum. It is distinguished from other cells in the brain by selective expression of Gja1 (Mmus), Lhx2 (Mmus), Gpc5 (Mmus), Nr2f1 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Subclass:319 Astro-TE NN. http://purl.obolibrary.org/obo/UBERON_0009537 vascular element of right lung http://purl.obolibrary.org/obo/UBERON_0005629 vascular plexus A vascular plexus that is part of a right lung. http://purl.obolibrary.org/obo/CL_4300362 tanycyte (Mmus) http://purl.obolibrary.org/obo/CL_0002085 tanycyte A tanycyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gpr50 (Mmus), Apoe (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Subclass:322 Tanycyte NN. http://purl.obolibrary.org/obo/UBERON_0009538 mesenchyme of sublingual gland primordium http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue Mesenchyme that is part of a sublingual gland primordium. http://purl.obolibrary.org/obo/CL_4300363 ependymal cell (Mmus) http://purl.obolibrary.org/obo/CL_0000065 ependymal cell A ependymal cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Tmem212 (Mmus), Rarres2 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Subclass:323 Ependymal NN. http://purl.obolibrary.org/obo/UBERON_0009539 mesenchyme of submandibular gland primordium http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue Mesenchyme that is part of a submandibular gland primordium. http://purl.obolibrary.org/obo/CL_4300367 oligodendrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4300031 OPC-Oligo cell (Mmus) A oligodendrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Cldn11 (Mmus), Gjc3 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Subclass:327 Oligo NN. http://purl.obolibrary.org/obo/UBERON_0009548 hepatic sinusoid of left lobe of liver http://purl.obolibrary.org/obo/UBERON_0001281 hepatic sinusoid A hepatic sinusoid that is part of a left lobe of liver. http://purl.obolibrary.org/obo/CL_4300370 VLMC NN vascular leptomeningeal cell (Mmus) http://purl.obolibrary.org/obo/CL_4023051 vascular leptomeningeal cell A vascular leptomeningeal cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Apod (Mmus), Slc6a13 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Subclass:330 VLMC NN. http://purl.obolibrary.org/obo/UBERON_0009549 hepatic sinusoid of right lobe of liver http://purl.obolibrary.org/obo/UBERON_0001281 hepatic sinusoid A hepatic sinusoid that is part of a right lobe of liver. http://purl.obolibrary.org/obo/CL_4301573 DCO Il22 Gly-Gaba_3 cerebellar neuron (Mmus) http://purl.obolibrary.org/obo/CL_4300348 DCO Il22 Gly-Gaba cerebellar neuron (Mmus) A cerebellar neuron of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Fat2 (Mmus), Slc6a5 (Mmus), Cgnl1 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1143 DCO Il22 Gly-Gaba_3. http://purl.obolibrary.org/obo/UBERON_0009550 endoderm of foregut-midgut junction http://purl.obolibrary.org/obo/UBERON_0000925 endoderm An endoderm that is part of a foregut-midgut junction. http://purl.obolibrary.org/obo/CL_4301576 CB PLI Gly-Gaba_3 Purkinje layer interneuron (Mmus) http://purl.obolibrary.org/obo/CL_4300349 Purkinje layer interneuron (Mmus) A Purkinje layer interneuron of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Pax2 (Mmus), C1ql3 (Mmus), Tfap2b (Mmus), Gabrb1 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1146 CB PLI Gly-Gaba_3. http://purl.obolibrary.org/obo/UBERON_0009551 distal segment of digit http://purl.obolibrary.org/obo/UBERON_0002529 limb segment A segment of a digit containing the distal phalanx, and overlapping the distal interphalangeal joint[CJM]. The digit tip is derived from multiple and distinct embryonic origins, and includes the distal bone with associated marrow cavity and haematopoietic cells, ventral (flexor) and dorsal (extensor) tendons, sweat glands with myoepithelial and luminal secreting cells and associated neurons for innervation, dermis with resident melanocytes and dendritic cells, mesenchyme with resident fibroblasts, skin epidermis with hair follicles, a nail organ composed of six specific parts (the root, nail bed, nail plate, eponychium (cuticle), perionychium and hyponychium). http://purl.obolibrary.org/obo/CL_4301578 cerebellar Golgi cell (Mmus) http://purl.obolibrary.org/obo/CL_4300028 cerebellar GABAergic neuron (Mmus) A cerebellar Golgi cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Zfp385c (Mmus), Tfap2b (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1148 CBX Golgi Gly-Gaba_1. http://purl.obolibrary.org/obo/UBERON_0009552 distal segment of manual digit http://purl.obolibrary.org/obo/UBERON_0009551 distal segment of digit A segment of the manual digit containing the distal phalanx. http://purl.obolibrary.org/obo/CL_4301580 CBX MLI Megf11 Gaba_2 molecular layer interneuron (Mmus) http://purl.obolibrary.org/obo/CL_4300351 CBX MLI Megf11 Gaba molecular layer interneuron (Mmus) A molecular layer interneuron of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gabra6 (Mmus), Pvalb (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1150 CBX MLI Megf11 Gaba_2. http://purl.obolibrary.org/obo/UBERON_0009553 distal segment of pedal digit http://purl.obolibrary.org/obo/UBERON_0009551 distal segment of digit A segment of the pedal digit containing the distal phalanx. Note this class represents a digit segment and thus includes tissues in addition to bone. http://purl.obolibrary.org/obo/UBERON_0009559 metacarpal/tarsal-phalangeal joint http://purl.obolibrary.org/obo/UBERON_0011139 synovial limb joint A skeletal joint that connects a mesopodium bone and connects a proximal phalanx. http://purl.obolibrary.org/obo/CL_4301583 CBX Purkinje Gaba_2 Purkinje cell (Mmus) http://purl.obolibrary.org/obo/CL_4300353 Purkinje cell (Mmus) A Purkinje cell of the Mus musculus brain. Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1153 CBX Purkinje Gaba_2. http://purl.obolibrary.org/obo/UBERON_0009564 distal limb integumentary appendage http://purl.obolibrary.org/obo/UBERON_0013703 integumentary projection A nail, hoof or claw. http://purl.obolibrary.org/obo/UBERON_0009565 nail of manual digit http://purl.obolibrary.org/obo/UBERON_0001705 nail A nail that is part of a manual digit. http://purl.obolibrary.org/obo/CL_4301586 unipolar brush cell (Mmus) http://purl.obolibrary.org/obo/CL_4300029 cerebellar glutamatergic neuron (Mmus) A unipolar brush cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Sln (Mmus), Lmx1a (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1156 DCO UBC Glut_1. http://purl.obolibrary.org/obo/UBERON_0009566 intestinal submucosa http://purl.obolibrary.org/obo/UBERON_0018257 submucosa of digestive tract A submucosa that is part of a intestine. http://purl.obolibrary.org/obo/CL_4301593 Astro-TE NN_3 astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4300359 astrocyte of cerebrum (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gja1 (Mmus), Grin2c (Mmus), Dcc (Mmus), Slc7a10 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1163 Astro-TE NN_3. http://purl.obolibrary.org/obo/UBERON_0009567 nail of pedal digit http://purl.obolibrary.org/obo/UBERON_0001705 nail A nail that is part of a pedal digit. http://purl.obolibrary.org/obo/CL_4301595 Astro-TE NN_5 astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4300359 astrocyte of cerebrum (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gja1 (Mmus), Thbs4 (Mmus), Kcnk10 (Mmus), Pak1 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1165 Astro-TE NN_5. http://purl.obolibrary.org/obo/UBERON_0009568 trunk region of vertebral column http://purl.obolibrary.org/obo/UBERON_0006077 subdivision of vertebral column Subdivision of vertebral column that corresponds to the trunk of the body, containing the trunk/presacral vertebrae. In organisms that have a thoracic and lumbar distinction, this corresponds to the sum of both of these regions. http://purl.obolibrary.org/obo/CL_4301597 Astro-OLF NN_2 astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4300360 olfactory areas astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gja1 (Mmus), Hs3st3a1 (Mmus), Slco1c1 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1167 Astro-OLF NN_2. http://purl.obolibrary.org/obo/UBERON_0009570 spinal cord sulcus limitans http://purl.obolibrary.org/obo/UBERON_0005478 sulcus limitans of neural tube A sulcus limitans of neural tube that is part of a future spinal cord. http://purl.obolibrary.org/obo/CL_4301602 Tanycyte NN_1 tanycyte (Mmus) http://purl.obolibrary.org/obo/CL_4300362 tanycyte (Mmus) A tanycyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Cnmd (Mmus), Lpl (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1172 Tanycyte NN_1. http://purl.obolibrary.org/obo/UBERON_0009571 ventral midline http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure In protostomes (such as insects, snails and worms) as well as deuterostomes (vertebrates), the midline is an embryonic region that functions in patterning of the adjacent nervous tissue. The ventral midline in insects is a cell population extending along the ventral surface of the embryo and is the region from which cells detach to form the ventrally located nerve cords. In vertebrates, the midline is originally located dorsally. During development, it folds inwards and becomes the ventral part of the dorsally located neural tube and is then called the ventral midline, or floor plate. http://purl.obolibrary.org/obo/CL_4301608 choroid plexus epithelial cell (Mmus) http://purl.obolibrary.org/obo/CL_0000706 choroid plexus epithelial cell A choroid plexus epithelial cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of 2900040C04Rik (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1178 CHOR NN_1. http://purl.obolibrary.org/obo/UBERON_0009572 lumen of central canal of spinal cord http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space A cerebrospinal fluid-filled space that runs longitudinally through the length of the entire spinal cord. The central canal is contiguous with the ventricular system of the brain. The central canal represents the adult remainder of the neural tube. http://purl.obolibrary.org/obo/CL_4301612 newly formed oligodendrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4300367 oligodendrocyte (Mmus) A newly formed oligodendrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of 9630013A20Rik (Mmus), Ptprb (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1182 NFOL NN_2. http://purl.obolibrary.org/obo/UBERON_0009576 medulla oblongata sulcus limitans http://purl.obolibrary.org/obo/UBERON_0005478 sulcus limitans of neural tube A sulcus limitans of neural tube that is part of a future medulla oblongata. http://purl.obolibrary.org/obo/CL_4301613 myelin-forming oligodendrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4300367 oligodendrocyte (Mmus) A myelin-forming oligodendrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Cldn11 (Mmus), Sec14l5 (Mmus), 9630013A20Rik (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1183 MFOL NN_3. http://purl.obolibrary.org/obo/UBERON_0009577 metencephalon sulcus limitans http://purl.obolibrary.org/obo/UBERON_0005478 sulcus limitans of neural tube A sulcus limitans of neural tube that is part of a future metencephalon. http://purl.obolibrary.org/obo/CL_4301615 olfactory ensheathing cell (Mmus) http://purl.obolibrary.org/obo/CL_0011028 olfactory ensheathing cell A olfactory ensheathing cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Apod (Mmus), Npy (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1185 OEC NN_1. http://purl.obolibrary.org/obo/UBERON_0009578 myelencephalon sulcus limitans http://purl.obolibrary.org/obo/UBERON_0005478 sulcus limitans of neural tube A sulcus limitans of neural tube that is part of a future myelencephalon. http://purl.obolibrary.org/obo/CL_4301616 arachnoid barrier cell (Mmus) http://purl.obolibrary.org/obo/CL_4023097 arachnoid barrier cell A arachnoid barrier cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Thbd (Mmus), Ccn3 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1186 ABC NN_1. http://purl.obolibrary.org/obo/UBERON_0009584 1st arch mandibular mesenchyme http://purl.obolibrary.org/obo/UBERON_0010042 1st arch mesenchyme Mesenchyme that is part of a 1st arch mandibular component. http://purl.obolibrary.org/obo/CL_4307027 cerebellar astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_0002603 astrocyte of the cerebellum A transcriptomically defined type of astrocyte localized exclusively in the cerebellum beneath the Purkinje cell layer. It is distinguished from other cells in the brain by selective expression of Dao (Mmus), Efemp1 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5207 Astro-CB NN_1. http://purl.obolibrary.org/obo/UBERON_0009602 left lung associated mesenchyme http://purl.obolibrary.org/obo/UBERON_0004883 lung mesenchyme Mesenchyme that is part of a developing left lung. http://purl.obolibrary.org/obo/CL_4307029 Astro-NT NN_1 Slc36a2 astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301589 Astro-NT NN_1 astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gfap (Mmus), Slc36a2 (Mmus), Sfrp5 (Mmus). It is distinguished from other Astro-NT NN_1 cells by expression of Slc36a2, Sfrp5. These cells are located in the Midbrain, Cerebellum, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5209 Astro-NT NN_1. http://purl.obolibrary.org/obo/UBERON_0009603 right lung associated mesenchyme http://purl.obolibrary.org/obo/UBERON_0004883 lung mesenchyme Mesenchyme that is part of a developing right lung. http://purl.obolibrary.org/obo/CL_4307034 Astro-NT NN_2 Fzd2 astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301590 Astro-NT NN_2 astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gja1 (Mmus), A330076C08Rik (Mmus), Sfrp5 (Mmus), Gria2 (Mmus). It is distinguished from other Astro-NT NN_2 cells by expression of Fzd2, Gria2, Ttll3. These cells are located in the Midbrain, Thalamus, Pons , in or close to the regions: Midbrain reticular nucleus . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5214 Astro-NT NN_2. http://purl.obolibrary.org/obo/UBERON_0009610 forebrain neural plate http://purl.obolibrary.org/obo/UBERON_0003075 neural plate A neural plate that develops_from a future forebrain. http://purl.obolibrary.org/obo/CL_4307038 Astro-TE NN_1 Myoc astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301591 Astro-TE NN_1 astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Myoc (Mmus), Lhx2 (Mmus), Kcne1l (Mmus), Alpk1 (Mmus). It is distinguished from other Astro-TE NN_1 cells by expression of Myoc, Kcne1l, Alpk1. These cells are located in the Isocortex, Olfactory areas, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5218 Astro-TE NN_1. http://purl.obolibrary.org/obo/UBERON_0009611 midbrain neural plate http://purl.obolibrary.org/obo/UBERON_0003075 neural plate A neural plate that develops_from a presumptive midbrain. http://purl.obolibrary.org/obo/CL_4307039 Astro-TE NN_1 Rasl10b astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301591 Astro-TE NN_1 astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gfap (Mmus), Ddn (Mmus), Myoc (Mmus), Rasl10b (Mmus). It is distinguished from other Astro-TE NN_1 cells by expression of Rasl10b, Igfbp5. These cells are located in the Hippocampal region, Isocortex, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5219 Astro-TE NN_1. http://purl.obolibrary.org/obo/UBERON_0009614 hindbrain neural plate http://purl.obolibrary.org/obo/UBERON_0003075 neural plate A neural plate that develops_from a presumptive hindbrain. http://purl.obolibrary.org/obo/CL_4307044 Astro-TE NN_3 Cxcl5 astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301593 Astro-TE NN_3 astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gja1 (Mmus), Cxcl5 (Mmus), Ddn (Mmus). It is distinguished from other Astro-TE NN_3 cells by expression of Cxcl5, Kif5a. These cells are located in the Hippocampal region, Isocortex, Olfactory areas, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5224 Astro-TE NN_3. http://purl.obolibrary.org/obo/UBERON_0009616 presumptive midbrain http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure A presumptive structure that has the potential to develop into a midbrain. http://purl.obolibrary.org/obo/CL_4307045 Astro-TE NN_3 Fam163a astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301593 Astro-TE NN_3 astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of S1pr1 (Mmus), Fam163a (Mmus), Kcnq3 (Mmus), Kcnq1ot1 (Mmus). It is distinguished from other Astro-TE NN_3 cells by expression of Fam163a, Nr2f1, Kcnq1ot1. These cells are located in the Isocortex, Olfactory areas . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5225 Astro-TE NN_3. http://purl.obolibrary.org/obo/UBERON_0009617 head paraxial mesoderm http://purl.obolibrary.org/obo/UBERON_0005253 head mesenchyme Bilateral mesenchymal mesoderm parallel and immediately adjacent to the neural tube/notochord; it generates a subset of extra-ocular, and other head, muscles. http://purl.obolibrary.org/obo/CL_4307047 Astro-TE NN_3 Crym astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301593 Astro-TE NN_3 astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of S1pr1 (Mmus), Crym (Mmus), Grin2c (Mmus). It is distinguished from other Astro-TE NN_3 cells by expression of Crym, Gabbr2. These cells are located in the Striatum dorsal region, Striatum ventral region , in or close to the regions: Nucleus accumbens, Caudoputamen . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5227 Astro-TE NN_3. http://purl.obolibrary.org/obo/UBERON_0009621 tail somite http://purl.obolibrary.org/obo/UBERON_0002329 somite A somite that is part of a tail. http://purl.obolibrary.org/obo/CL_4307048 Astro-TE NN_4 astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4300359 astrocyte of cerebrum (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of S1pr1 (Mmus), Thbs4 (Mmus), Gm29683 (Mmus), Slc39a12 (Mmus). It is distinguished from other Astro-TE NN cells by expression of Gm29683. These cells are located in the Cortical subplate, brain , in or close to the regions: Lateral amygdalar nucleus, external capsule . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5228 Astro-TE NN_4. http://purl.obolibrary.org/obo/UBERON_0009622 pronephric proximal straight tubule http://purl.obolibrary.org/obo/UBERON_0005310 pronephric nephron tubule A proximal straight tubule that is part of a pronephros. http://purl.obolibrary.org/obo/CL_4307050 Astro-TE NN_5 Adamts18 astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301595 Astro-TE NN_5 astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of S1pr1 (Mmus), Adamts18 (Mmus), Crym (Mmus). It is distinguished from other Astro-TE NN_5 cells by expression of Adamts18. These cells are located in the Lateral septal complex, Striatum dorsal region, brain , in or close to the regions: Nucleus accumbens, Caudoputamen, lateral ventricle . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5230 Astro-TE NN_5. http://purl.obolibrary.org/obo/UBERON_0009623 spinal nerve root http://purl.obolibrary.org/obo/UBERON_0002211 nerve root The paired bundles of nerve fibers entering and leaving the spinal cord at each segment. The dorsal and ventral nerve roots join to form the mixed segmental spinal nerves. The dorsal roots are generally afferent, formed by the central projections of the spinal (dorsal root) ganglia sensory cells, and the ventral roots efferent, comprising the axons of spinal motor and autonomic preganglionic neurons. There are, however, some exceptions to this afferent/efferent rule. http://purl.obolibrary.org/obo/CL_4307054 Astro-OLF NN_2 Alk astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301597 Astro-OLF NN_2 astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of S1pr1 (Mmus), Chrdl1 (Mmus), Sfrp1 (Mmus), Atp13a4 (Mmus). It is distinguished from other Astro-OLF NN_2 cells by expression of Alk, Atp13a4. These cells are located in the Olfactory areas , in or close to the regions: Anterior olfactory nucleus, Main olfactory bulb, granule layer, Main olfactory bulb, mitral layer . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5234 Astro-OLF NN_2. http://purl.obolibrary.org/obo/UBERON_0009624 lumbar nerve http://purl.obolibrary.org/obo/UBERON_0001780 spinal nerve The lumbar nerves are the five spinal nerves emerging from the lumbar vertebrae. They are divided into posterior and anterior divisions. http://purl.obolibrary.org/obo/CL_4307055 Astro-OLF NN_3 Ecrg4 astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301598 Astro-OLF NN_3 astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of C230072F16Rik (Mmus), Dipk1c (Mmus), Ecrg4 (Mmus). It is distinguished from other Astro-OLF NN_3 cells by expression of Ecrg4. These cells are located in the Olfactory areas , in or close to the regions: Main olfactory bulb, granule layer . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5235 Astro-OLF NN_3. http://purl.obolibrary.org/obo/UBERON_0009625 sacral nerve http://purl.obolibrary.org/obo/UBERON_0001780 spinal nerve The five sacral nerves emerge from the sacrum. Although the vertebral components of the sacrum are fused into a single bone, the sacral vertebrae are still used to number the sacral nerves. Posteriorly, they emerge from the posterior sacral foramina, and form the posterior branches of sacral nerves. Anteriorly, they emerge from the anterior sacral foramina, and contribute to the sacral plexus (S1-S4) and coccygeal plexus. http://purl.obolibrary.org/obo/CL_4307056 Astro-OLF NN_3 Sfrp1 astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301598 Astro-OLF NN_3 astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of S1pr1 (Mmus), 6530411M01Rik (Mmus), Sfrp1 (Mmus), Aqp4 (Mmus). It is distinguished from other Astro-OLF NN_3 cells by expression of Sfrp1, Aqp4. These cells are located in the Olfactory areas , in or close to the regions: Main olfactory bulb, granule layer, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5236 Astro-OLF NN_3. http://purl.obolibrary.org/obo/UBERON_0009630 root of thoracic nerve http://purl.obolibrary.org/obo/UBERON_0009623 spinal nerve root A spinal nerve root that is part of a thoracic nerve. http://purl.obolibrary.org/obo/CL_4307063 Tanycyte NN_1 Cnmd tanycyte of subfornical organ (Mmus) http://purl.obolibrary.org/obo/CL_4301602 Tanycyte NN_1 tanycyte (Mmus) A tanycyte of subfornical organ of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Cnmd (Mmus), Sfta3-ps (Mmus). It is distinguished from other Tanycyte NN_1 cells by expression of Cnmd. These cells are located in the brain , in or close to the regions: choroid plexus, third ventricle . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5243 Tanycyte NN_1. http://purl.obolibrary.org/obo/UBERON_0009631 root of lumbar spinal nerve http://purl.obolibrary.org/obo/UBERON_0009623 spinal nerve root A spinal nerve root that is part of a lumbar nerve. http://purl.obolibrary.org/obo/CL_4307064 Tanycyte NN_1 Glp1r tanycyte (Mmus) http://purl.obolibrary.org/obo/CL_4301602 Tanycyte NN_1 tanycyte (Mmus) A tanycyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of C230072F16Rik (Mmus), Glp1r (Mmus). It is distinguished from other Tanycyte NN_1 cells by expression of Glp1r. These cells are located in the Hypothalamus, brain , in or close to the regions: Anteroventral periventricular nucleus . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5244 Tanycyte NN_1. http://purl.obolibrary.org/obo/UBERON_0009633 root of sacral nerve http://purl.obolibrary.org/obo/UBERON_0009623 spinal nerve root A spinal nerve root that is part of a sacral nerve. http://purl.obolibrary.org/obo/CL_4307065 Tanycyte NN_2 Mylk3 alpha1-tanycyte (Mmus) http://purl.obolibrary.org/obo/CL_4301603 Tanycyte NN_2 tanycyte (Mmus) A alpha1-tanycyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Dynlrb2 (Mmus), Mylk3 (Mmus), Sfta3-ps (Mmus). It is distinguished from other Tanycyte NN_2 cells by expression of Mylk3. It is glutamatergic (inferred from expression of Slc17a8). These cells are located in the Hypothalamus , in or close to the regions: Periventricular hypothalamic nucleus, intermediate part . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5245 Tanycyte NN_2. http://purl.obolibrary.org/obo/UBERON_0009646 lumbar sympathetic nerve trunk http://purl.obolibrary.org/obo/UBERON_0004295 sympathetic nerve trunk A sympathetic nerve trunk that is part of a lower back. http://purl.obolibrary.org/obo/CL_4307066 Tanycyte NN_2 Mroh5 alpha1-tanycyte (Mmus) http://purl.obolibrary.org/obo/CL_4301603 Tanycyte NN_2 tanycyte (Mmus) A alpha1-tanycyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Ccdc170 (Mmus), Nkx2-4 (Mmus), Dock8 (Mmus). It is distinguished from other Tanycyte NN_2 cells by expression of Mroh5. These cells are located in the Hypothalamus, brain , in or close to the regions: Periventricular hypothalamic nucleus, intermediate part, third ventricle, Arcuate hypothalamic nucleus . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5246 Tanycyte NN_2. http://purl.obolibrary.org/obo/UBERON_0009647 tympanic membrane epithelium http://purl.obolibrary.org/obo/UBERON_0015813 middle ear epithelium One of the two epithelia which make up the tympanic membrane (along with the fibrous layer). http://purl.obolibrary.org/obo/CL_4307067 alpha2-tanycyte (Mmus) http://purl.obolibrary.org/obo/CL_4301603 Tanycyte NN_2 tanycyte (Mmus) A alpha2-tanycyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Pdzph1 (Mmus), Wdr63 (Mmus), Dscaml1 (Mmus), P3h2 (Mmus). It is distinguished from other Tanycyte NN_2 cells by expression of Dscaml1, P3h2. These cells are located in the Hypothalamus , in or close to the regions: Periventricular hypothalamic nucleus, posterior part, Arcuate hypothalamic nucleus . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5247 Tanycyte NN_2. http://purl.obolibrary.org/obo/UBERON_0009648 eyelid subcutaneous connective tissue http://purl.obolibrary.org/obo/UBERON_0003581 eyelid connective tissue An eyelid connective tissue that is part of a hypodermis. http://purl.obolibrary.org/obo/CL_4307068 Tanycyte NN_2 Otx2 tanycyte (Mmus) http://purl.obolibrary.org/obo/CL_4301603 Tanycyte NN_2 tanycyte (Mmus) A tanycyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Ccdc146 (Mmus), Tbx3 (Mmus), Otx2 (Mmus). It is distinguished from other Tanycyte NN_2 cells by expression of Otx2, Nkx2-4. These cells are located in the Hypothalamus, brain , in or close to the regions: Periventricular hypothalamic nucleus, posterior part, third ventricle . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5248 Tanycyte NN_2. http://purl.obolibrary.org/obo/UBERON_0009651 nephron tubule basement membrane http://purl.obolibrary.org/obo/UBERON_0005769 basement membrane of epithelium A basement membrane that is part of a nephron tubule. http://purl.obolibrary.org/obo/CL_4307070 beta-2 tanycyte (Mmus) http://purl.obolibrary.org/obo/CL_4300362 tanycyte (Mmus) A beta2-tanycyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Fndc3c1 (Mmus), Ecrg4 (Mmus). It is distinguished from other Tanycyte NN cells by expression of Ecrg4. These cells are located in the Hypothalamus, brain , in or close to the regions: Median eminence, third ventricle, Arcuate hypothalamic nucleus . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5250 Tanycyte NN_3. http://purl.obolibrary.org/obo/UBERON_0009652 bronchus basement membrane http://purl.obolibrary.org/obo/UBERON_0015329 respiratory system basement membrane A basement membrane that is part of a bronchus. http://purl.obolibrary.org/obo/CL_4307087 OPC NN_1 Irx2 oligodendrocyte precursor cell (Mmus) http://purl.obolibrary.org/obo/CL_4300366 oligodendrocyte precursor cell (Mmus) A oligodendrocyte precursor cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Pdgfra (Mmus), Pclaf (Mmus), Irx2 (Mmus). It is distinguished from other OPC NN_1 cells by expression of Neil3, Irx2. These cells are located in the Cerebellum, brain, Midbrain, Pons, Medulla . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5267 OPC NN_1. http://purl.obolibrary.org/obo/UBERON_0009653 trachea basement membrane http://purl.obolibrary.org/obo/UBERON_0015329 respiratory system basement membrane A basement membrane that is part of a trachea. http://purl.obolibrary.org/obo/CL_4307088 OPC NN_1 Mms22l oligodendrocyte precursor cell (Mmus) http://purl.obolibrary.org/obo/CL_4300366 oligodendrocyte precursor cell (Mmus) A oligodendrocyte precursor cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Pdgfra (Mmus), Olig1 (Mmus), Mms22l (Mmus), Top2a (Mmus). It is distinguished from other OPC NN_1 cells by expression of Mms22l, Foxg1, Top2a. These cells are located in the Isocortex, Olfactory areas, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5268 OPC NN_1. http://purl.obolibrary.org/obo/UBERON_0009655 auricular artery http://purl.obolibrary.org/obo/UBERON_0001637 artery An artery that supplies oxygenated blood to the ear. http://purl.obolibrary.org/obo/CL_4307089 OPC NN_1 Col27a1 oligodendrocyte precursor cell (Mmus) http://purl.obolibrary.org/obo/CL_4300366 oligodendrocyte precursor cell (Mmus) A oligodendrocyte precursor cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Pdgfra (Mmus), Olig1 (Mmus), Col27a1 (Mmus). It is distinguished from other OPC NN_1 cells by expression of Col27a1. These cells are located in the Midbrain, Pons, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5269 OPC NN_1. http://purl.obolibrary.org/obo/UBERON_0009661 midbrain nucleus http://purl.obolibrary.org/obo/UBERON_0002308 nucleus of brain Nucleus located in the midbrain. http://purl.obolibrary.org/obo/CL_4307092 COP NN_1 Rgcc committed oligodendrocyte precursor (Mmus) http://purl.obolibrary.org/obo/CL_4301611 commited oligodendrocyte precursor (Mmus) A committed oligodendrocyte precursor of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gpr17 (Mmus), Bmp4 (Mmus), Zfp36l1 (Mmus). It is distinguished from other COP NN_1 cells by expression of Rgcc, Plpp4. These cells are located in the Isocortex, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5272 COP NN_1. http://purl.obolibrary.org/obo/UBERON_0009662 hindbrain nucleus http://purl.obolibrary.org/obo/UBERON_0002308 nucleus of brain Nucleus located within the hindbrain. http://purl.obolibrary.org/obo/CL_4307093 COP NN_1 9130019P16Rik committed oligodendrocyte precursor (Mmus) http://purl.obolibrary.org/obo/CL_4301611 commited oligodendrocyte precursor (Mmus) A committed oligodendrocyte precursor of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gpr17 (Mmus), Gp1bb (Mmus), Pdzd2 (Mmus), Plekhg1 (Mmus). It is distinguished from other COP NN_1 cells by expression of Rgcc, 9130019P16Rik. These cells are located in the Isocortex, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5273 COP NN_1. http://purl.obolibrary.org/obo/UBERON_0009663 telencephalic nucleus http://purl.obolibrary.org/obo/UBERON_0002308 nucleus of brain A nucleus of brain that is part of a telencephalon. http://purl.obolibrary.org/obo/CL_4307094 COP NN_1 C1ql1 committed oligodendrocyte precursor (Mmus) http://purl.obolibrary.org/obo/CL_4301611 commited oligodendrocyte precursor (Mmus) A committed oligodendrocyte precursor of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gpr17 (Mmus), Bgn (Mmus), Gstp1 (Mmus), C1ql1 (Mmus). It is distinguished from other COP NN_1 cells by expression of C1ql1, Gstp1. These cells are located in the brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5274 COP NN_1. http://purl.obolibrary.org/obo/UBERON_0009668 ventral mesentery http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure Ventral mesentery is the part of the peritoneum closest to the navel. http://purl.obolibrary.org/obo/CL_4307096 COP NN_1 Vwc2 committed oligodendrocyte precursor (Mmus) http://purl.obolibrary.org/obo/CL_4301611 commited oligodendrocyte precursor (Mmus) A committed oligodendrocyte precursor of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of 9630013A20Rik (Mmus), Rab32 (Mmus), Opalin (Mmus). It is distinguished from other COP NN_1 cells by expression of Vwc2, Opalin. These cells are located in the brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5276 COP NN_1. http://purl.obolibrary.org/obo/UBERON_0009669 embryonic cloacal lumen http://purl.obolibrary.org/obo/UBERON_0012463 cloacal lumen An anatomical space that surrounded_by a embryonic cloaca. http://purl.obolibrary.org/obo/CL_4307098 NFOL NN_2 9630013A20Rik newly formed oligodendrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301612 newly formed oligodendrocyte (Mmus) A newly formed oligodendrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of 9630013A20Rik (Mmus), Grin2b (Mmus). It is distinguished from other NFOL NN_2 cells by expression of 9630013A20Rik, Grin2b. These cells are located in the Midbrain, Thalamus, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5278 NFOL NN_2. http://purl.obolibrary.org/obo/UBERON_0009670 rectal lumen http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space An anatomical space that surrounded_by a rectum. http://purl.obolibrary.org/obo/CL_4307099 NFOL NN_2 Dbx2 newly formed oligodendrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301612 newly formed oligodendrocyte (Mmus) A newly formed oligodendrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of 9630013A20Rik (Mmus), Dbx2 (Mmus), Rassf10 (Mmus). It is distinguished from other NFOL NN_2 cells by expression of Dbx2, Rassf10. These cells are located in the Isocortex, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5279 NFOL NN_2. http://purl.obolibrary.org/obo/UBERON_0009678 tooth row http://purl.obolibrary.org/obo/UBERON_0034926 anatomical row Anatomical cluster consisting of adjacent teeth constituting a row. http://purl.obolibrary.org/obo/CL_4307100 NFOL NN_2 Rgs16 newly formed oligodendrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301612 newly formed oligodendrocyte (Mmus) A newly formed oligodendrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of 9630013A20Rik (Mmus), Rgs16 (Mmus), Rhbdl2 (Mmus). It is distinguished from other NFOL NN_2 cells by expression of Rgs16, Rhbdl2. These cells are located in the Isocortex, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5280 NFOL NN_2. http://purl.obolibrary.org/obo/UBERON_0009679 set of lower jaw teeth http://purl.obolibrary.org/obo/UBERON_0009678 tooth row A tooth row that is part of a skeleton of lower jaw. http://purl.obolibrary.org/obo/CL_4307101 NFOL NN_2 Il23a newly formed oligodendrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301612 newly formed oligodendrocyte (Mmus) A newly formed oligodendrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of 9630013A20Rik (Mmus), Piezo2 (Mmus), Ptprb (Mmus). It is distinguished from other NFOL NN_2 cells by expression of Il23a, Opalin, Ptprb. These cells are located in the Isocortex, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5281 NFOL NN_2. http://purl.obolibrary.org/obo/UBERON_0009680 set of upper jaw teeth http://purl.obolibrary.org/obo/UBERON_0009678 tooth row A tooth row that is part of a skeleton of upper jaw. http://purl.obolibrary.org/obo/CL_4307102 MFOL NN_3 Cxcl12 myelin-forming oligodendrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301613 myelin-forming oligodendrocyte (Mmus) A myelin-forming oligodendrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Opalin (Mmus), Cxcl12 (Mmus), Efhd1 (Mmus). It is distinguished from other MFOL NN_3 cells by expression of Cxcl12, Efhd1. These cells are located in the Isocortex, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5282 MFOL NN_3. http://purl.obolibrary.org/obo/UBERON_0009692 lumen of pharyngotympanic tube http://purl.obolibrary.org/obo/UBERON_0005082 tube lumen An organ cavity that is part of a pharyngotympanic tube. http://purl.obolibrary.org/obo/CL_4307103 MFOL NN_3 Il23a myelin-forming oligodendrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301613 myelin-forming oligodendrocyte (Mmus) A myelin-forming oligodendrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of 9630013A20Rik (Mmus), Ppp1r14a (Mmus), Mroh3 (Mmus). It is distinguished from other MFOL NN_3 cells by expression of Il23a, Ppp1r14a. These cells are located in the Midbrain, Isocortex, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5283 MFOL NN_3. http://purl.obolibrary.org/obo/UBERON_0009697 epithelium of appendix http://purl.obolibrary.org/obo/UBERON_0001278 epithelium of large intestine An epithelium that is part of a vermiform appendix. http://purl.obolibrary.org/obo/CL_4307104 MOL NN_4 Plin3 mature myelinating oligodendrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301614 mature myelinating oligodendrocyte (Mmus) A mature myelinating oligodendrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Prr5l (Mmus), Hapln2 (Mmus), Enpp6 (Mmus), Grm7 (Mmus). It is distinguished from other MOL NN_4 cells by expression of Plin3, Grm7. These cells are located in the Medulla, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5284 MOL NN_4. http://purl.obolibrary.org/obo/UBERON_0009712 endocardium of right ventricle http://purl.obolibrary.org/obo/UBERON_0001081 endocardium of ventricle Any endocardium that is part of the right ventricle of the heart. http://purl.obolibrary.org/obo/CL_4307105 MOL NN_4 Spock3 mature myelinating oligodendrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301614 mature myelinating oligodendrocyte (Mmus) A mature myelinating oligodendrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Cldn11 (Mmus), A230001M10Rik (Mmus), Spock3 (Mmus), Rhoj (Mmus). It is distinguished from other MOL NN_4 cells by expression of Spock3, Rhoj. These cells are located in the Midbrain, Isocortex, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5285 MOL NN_4. http://purl.obolibrary.org/obo/UBERON_0009713 endocardium of left ventricle http://purl.obolibrary.org/obo/UBERON_0001081 endocardium of ventricle Any endocardium that is part of the left ventricle of the heart. http://purl.obolibrary.org/obo/CL_4307106 MOL NN_4 Art3 mature myelinating oligodendrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301614 mature myelinating oligodendrocyte (Mmus) A mature myelinating oligodendrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Apod (Mmus), Klk6 (Mmus), Dlc1 (Mmus). It is distinguished from other MOL NN_4 cells by expression of Art3. These cells are located in the Medulla, Pons, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5286 MOL NN_4. http://purl.obolibrary.org/obo/UBERON_0009714 intermaxillary process http://purl.obolibrary.org/obo/UBERON_0009292 embryonic nasal process The primordial mass of tissue formed by the merging of the medial nasal prominences of the embryo; it contributes to the intermaxillary portion of the upper jaw, the prolabial portion of the upper lip, and the primary palate. http://purl.obolibrary.org/obo/CL_4307107 MOL NN_4 Il33 mature myelinating oligodendrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301614 mature myelinating oligodendrocyte (Mmus) A mature myelinating oligodendrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Opalin (Mmus), Grm3 (Mmus), Gm5087 (Mmus). It is distinguished from other MOL NN_4 cells by expression of Il33, Gm5087. These cells are located in the Isocortex, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5287 MOL NN_4. http://purl.obolibrary.org/obo/UBERON_0009715 stomodeal lumen http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space An anatomical cavity that surrounded_by a stomodeum. http://purl.obolibrary.org/obo/CL_4307108 MOL NN_4 Sspo mature myelinating oligodendrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301614 mature myelinating oligodendrocyte (Mmus) A mature myelinating oligodendrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Mog (Mmus), Anln (Mmus), Gm32633 (Mmus). It is distinguished from other MOL NN_4 cells by expression of Sspo, Selenop. These cells are located in the Isocortex, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5288 MOL NN_4. http://purl.obolibrary.org/obo/UBERON_0009731 sublaminar layers S3 or S4 http://purl.obolibrary.org/obo/UBERON_0009736 sublaminar layers S3 or S4 or S5 One of sublaminar layers S3 or S4. http://purl.obolibrary.org/obo/CL_4307111 OEC NN_1 A330076C08Rik olfactory ensheathing cell (Mmus) http://purl.obolibrary.org/obo/CL_4301615 olfactory ensheathing cell (Mmus) A olfactory ensheathing cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Apod (Mmus), Mybpc1 (Mmus), Syk (Mmus). It is distinguished from other OEC cells by expression of A330076C08Rik. These cells are located in the Olfactory areas, brain , in or close to the regions: olfactory nerve layer of main olfactory bulb, Main olfactory bulb . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5291 OEC NN_1. http://purl.obolibrary.org/obo/UBERON_0009732 sublaminar layers S1 or S2 or S5 http://purl.obolibrary.org/obo/UBERON_0008921 substratum of layer of retina One of sublaminar layers S1, S2, or S5. http://purl.obolibrary.org/obo/CL_4307112 OEC NN_1 Rasgef1c olfactory ensheathing cell (Mmus) http://purl.obolibrary.org/obo/CL_4301615 olfactory ensheathing cell (Mmus) A olfactory ensheathing cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Apod (Mmus), Mybpc1 (Mmus), Rasgef1c (Mmus). It is distinguished from other OEC cells by expression of Rasgef1c. It is glutamatergic (inferred from expression of Slc17a7). These cells are located in the brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5292 OEC NN_1. http://purl.obolibrary.org/obo/UBERON_0009733 sublaminar layers S1 or S2 or S3 http://purl.obolibrary.org/obo/UBERON_0009737 sublaminar layers S1 or S2 or S3 or S4 One of sublaminar layers S1, S2, or S3. http://purl.obolibrary.org/obo/CL_4307115 ABC NN_1 Cubn arachnoid barrier cell (Mmus) http://purl.obolibrary.org/obo/CL_4301616 arachnoid barrier cell (Mmus) A arachnoid barrier cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Prg4 (Mmus), Cubn (Mmus). It is distinguished from other ABC NN cells by expression of Cubn. These cells are located in the brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5295 ABC NN_1. http://purl.obolibrary.org/obo/UBERON_0009734 sublaminar layers S2 or S3 or S4 http://purl.obolibrary.org/obo/UBERON_0009737 sublaminar layers S1 or S2 or S3 or S4 One of sublaminar layers S2, S3, or S4. http://purl.obolibrary.org/obo/CL_4307132 microglial cell (Mmus) http://purl.obolibrary.org/obo/CL_0000129 microglial cell A microglial cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of C1qa (Mmus), Tmem119 (Mmus). It is distinguished from other Immune cells by expression of C1qa, Tmem119. These cells are located in the Isocortex, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5312 Microglia NN_1. http://purl.obolibrary.org/obo/UBERON_0009735 sublaminar layers S1 or S3 or S4 http://purl.obolibrary.org/obo/UBERON_0009737 sublaminar layers S1 or S2 or S3 or S4 One of sublaminar layers S1, S3, or S4. http://purl.obolibrary.org/obo/GO_0110095 cellular detoxification of aldehyde http://purl.obolibrary.org/obo/GO_1990748 cellular detoxification Any process carried out at the cellular level that reduces or removes the toxicity of an aldehyde. These may include transport of aldehydes away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance. http://purl.obolibrary.org/obo/UBERON_0009736 sublaminar layers S3 or S4 or S5 http://purl.obolibrary.org/obo/UBERON_0008921 substratum of layer of retina One of sublaminar layers S3, S4, or S5. http://purl.obolibrary.org/obo/GO_0150098 glial cell-neuron signaling http://purl.obolibrary.org/obo/GO_0007267 cell-cell signaling Cell-cell signaling that mediates the transfer of information from a glial cell to a neuron. This signaling has been shown to be mediated by various molecules, depending on which glial cells release them, and in which tissues the signaling occurs, e.g. microglial cell-derived nerve growth factor (NGF) in the retina, or microglial cell-derived superoxide ions in the cerebellum. http://purl.obolibrary.org/obo/UBERON_0009737 sublaminar layers S1 or S2 or S3 or S4 http://purl.obolibrary.org/obo/UBERON_0008921 substratum of layer of retina One of sublaminar layers S1, S2, S3, or S4. http://purl.obolibrary.org/obo/UBERON_0036295 renal pelvis/ureter http://purl.obolibrary.org/obo/UBERON_0000477 anatomical cluster The upper tract of the renal system. The renal pelvis is the large cavity in the middle of each kidney. Urine drains from each kidney through a long tube called the ureter, into the bladder, where it is stored until it is passed from the body through the urethra. http://purl.obolibrary.org/obo/UBERON_0009738 border of sublaminar layers S1 and S2 http://purl.obolibrary.org/obo/UBERON_0009740 border between sublaminar layers The region extending out from the boundary between layers S1 and S2. http://purl.obolibrary.org/obo/GO_0140353 lipid export from cell http://purl.obolibrary.org/obo/GO_0006869 lipid transport The directed movement of a lipid from a cell, into the extracellular region. http://purl.obolibrary.org/obo/UBERON_0009739 border of sublaminar layers S3 and S4 http://purl.obolibrary.org/obo/UBERON_0009740 border between sublaminar layers The region extending out from the boundary between sublaminar layers S3 and S4. http://purl.obolibrary.org/obo/GO_0150115 cell-substrate junction organization http://purl.obolibrary.org/obo/GO_0034330 cell junction organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell-substrate junction. A cell-substrate junction is a specialized region of connection between a cell and the extracellular matrix. http://purl.obolibrary.org/obo/UBERON_0009740 border between sublaminar layers http://purl.obolibrary.org/obo/UBERON_0022303 nervous system cell part layer A region of the retina corresponding to a portion of two adjacent substratum layers. http://purl.obolibrary.org/obo/GO_0062171 lutein biosynthetic process http://purl.obolibrary.org/obo/GO_0016123 xanthophyll biosynthetic process The chemical reactions and pathways resulting in the formation of lutein. http://purl.obolibrary.org/obo/UBERON_0009744 lymph node medullary sinus http://purl.obolibrary.org/obo/UBERON_0004111 anatomical conduit The channels in the lymph node medulla that separate the medullary cords and are crossed by a reticulum of cells and fibers and bounded by littoral cells; lymph flows through the medullary sinus from the cortical sinuses and into the efferent lymphatic vessels. http://purl.obolibrary.org/obo/GO_0062172 lutein catabolic process http://purl.obolibrary.org/obo/GO_0016124 xanthophyll catabolic process The chemical reactions and pathways resulting in the breakdown of lutein. http://purl.obolibrary.org/obo/UBERON_0009745 lymph node medullary cord http://purl.obolibrary.org/obo/UBERON_0000064 organ part The dense rope-like structures of lymphatic tissue located between the medullary sinuses in the medulla of a lymph node. http://purl.obolibrary.org/obo/GO_0062177 radial spoke assembly http://purl.obolibrary.org/obo/GO_0065003 protein-containing complex assembly The aggregation, arrangement and bonding together of a set of components to form the radial spoke, a protein complex that links the outer microtubule doublet of the ciliary or flagellum axoneme with the sheath that surrounds the central pair of microtubules. http://purl.obolibrary.org/obo/UBERON_0009749 limb mesenchyme http://purl.obolibrary.org/obo/UBERON_0003104 mesenchyme The primordial embryonic connective tissue of the developing limbs, autopods and digits, consisting of mesenchymal cells supported in interlaminar jelly, that derive mostly from the mesoderm and contribute to limb connective tissue, bone and musculature in conjunction with myotome cells. http://purl.obolibrary.org/obo/GO_0150116 regulation of cell-substrate junction organization http://purl.obolibrary.org/obo/GO_0051128 regulation of cellular component organization Any process that modulates the frequency, rate or extent of cell-substrate junction organization. http://purl.obolibrary.org/obo/UBERON_0009751 cardiac mesenchyme http://purl.obolibrary.org/obo/UBERON_0003104 mesenchyme The embryonic connective tissue made up of loosely aggregated mesenchymal cells, supported by interlaminar jelly, that gives rise to the developing cardiac structures. http://purl.obolibrary.org/obo/GO_0062247 chloroplast vesicle http://purl.obolibrary.org/obo/GO_0031410 cytoplasmic vesicle A intracellular vesicle that is part of a chloroplast. http://purl.obolibrary.org/obo/UBERON_0009752 pancreas mesenchyme http://purl.obolibrary.org/obo/UBERON_0003104 mesenchyme The embryonic connective tissue made up of loosely aggregated mesenchymal cells, supported by interlaminar jelly, that gives rise to the developing pancreas. http://purl.obolibrary.org/obo/CL_0008037 gamma motor neuron http://purl.obolibrary.org/obo/CL_0008039 lower motor neuron A lower motor neuron that innervates only intrafusal muscle fibers. Unlike the alpha motor neurons, gamma motor neurons do not directly adjust the lengthening or shortening of muscles but function in adjusting the sensitivity of muscle spindles and in keeping muscle spindles taut, thereby allowing the continued firing of alpha neurons. http://purl.obolibrary.org/obo/UBERON_0009758 abdominal ganglion http://purl.obolibrary.org/obo/UBERON_0007134 trunk ganglion A ganglion that is part of a abdominal segment of trunk. http://purl.obolibrary.org/obo/CL_0009009 paneth cell of colon http://purl.obolibrary.org/obo/CL_1001588 colon glandular cell A paneth cell that is located in the epithelium of the colon. http://purl.obolibrary.org/obo/UBERON_0009767 proximal interphalangeal joint http://purl.obolibrary.org/obo/UBERON_0006658 interphalangeal joint An inter-phalangeal joint that connects a proximal phalanx to either a medial or distal phalanx. http://purl.obolibrary.org/obo/CL_0009010 transit amplifying cell http://purl.obolibrary.org/obo/CL_0000000 cell Transit-amplifying cells (TACs) are an undifferentiated population in transition between stem cells and differentiated cells. http://purl.obolibrary.org/obo/UBERON_0009768 distal interphalangeal joint http://purl.obolibrary.org/obo/UBERON_0006658 interphalangeal joint An inter-phalangeal joint that connects a distal phalanx to either a medial or proximal phalanx. http://purl.obolibrary.org/obo/CL_0009011 transit amplifying cell of colon http://purl.obolibrary.org/obo/CL_0002253 epithelial cell of large intestine A rapidly proliferating population of cells that differentiate from stem cells of the intestinal crypt of the colon. Stem cells located in the crypts of Lieberkühn give rise to proliferating progenitor or transit amplifying cells that differentiate into the four major epithelial cell types. These include columnar absorptive cells or enterocytes, mucous secreting goblet cells, enteroendocrine cells and paneth cells. http://purl.obolibrary.org/obo/UBERON_0009773 renal tubule http://purl.obolibrary.org/obo/UBERON_0006555 excretory tube A renal tubule is a tube that filters, re-absorbs and secretes substances to rid an organism of waste and to play a role in fluid homeostasis. http://purl.obolibrary.org/obo/CL_0009012 transit amplifying cell of small intestine http://purl.obolibrary.org/obo/CL_0002254 epithelial cell of small intestine A rapidly proliferating population of cells that differentiate from stem cells of the intestinal crypt of the small intestine. Stem cells located in the crypts of Lieberkühn give rise to proliferating progenitor or transit amplifying cells that differentiate into the four major epithelial cell types. These include columnar absorptive cells or enterocytes, mucous secreting goblet cells, enteroendocrine cells and paneth cells. http://purl.obolibrary.org/obo/UBERON_0009778 pleural sac http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure A serous sac that has the pleura and the pleural cavity as parts. http://purl.obolibrary.org/obo/CL_0009014 Peyer's patch lymphocyte http://purl.obolibrary.org/obo/CL_0000542 lymphocyte A lymphocyte that is part of a Peyer's patch. These cells have a major role in driving the immune response to antigens sampled from the intestinal lumen, and in regulating the formation of follicle-associated epithelium and M cells in Peyer's patches by converting intestitial enterocytes into M cells. http://purl.obolibrary.org/obo/UBERON_0009841 upper rhombic lip http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain Anterior-most region of dorsal hindbrain within rhombomere 1, adjacent the midbrain-hindbrain boundary. http://purl.obolibrary.org/obo/CL_0009015 Peyer's patch follicular dendritic cell http://purl.obolibrary.org/obo/CL_0000442 follicular dendritic cell A follicular dendritic cell located in the Peyer's patch. These cells from a meshwork in which Peyer's patch B cells reside. http://purl.obolibrary.org/obo/UBERON_0009842 glandular acinus http://purl.obolibrary.org/obo/UBERON_0034922 cell cluster The many-lobed berry cluster of cells that is the terminous of a gland where the secretion is produced is acinar in form. http://purl.obolibrary.org/obo/CL_0009016 intestinal crypt stem cell of large intestine http://purl.obolibrary.org/obo/CL_0002253 epithelial cell of large intestine An intestinal stem cell that is located in the large intestine crypt of Liberkuhn. These stem cells reside at the bottom of crypts in the large intestine and are highly proliferative. They either differentiate into transit amplifying cells or self-renew to form new stem cells. http://purl.obolibrary.org/obo/UBERON_0009843 prostate epithelial cord http://purl.obolibrary.org/obo/UBERON_0005154 epithelial cord A solid cord of prostate epithelium. http://purl.obolibrary.org/obo/CL_0009017 intestinal crypt stem cell of small intestine http://purl.obolibrary.org/obo/CL_0002254 epithelial cell of small intestine An intestinal stem cell that is located in the small intestine crypt of Liberkuhn. These stem cells reside at the bottom of crypts in the small intestine and are highly proliferative. They either differentiate into transit amplifying cells or self-renew to form new stem cells. http://purl.obolibrary.org/obo/UBERON_0009844 urogenital sinus lumen http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space An anatomical space that surrounded_by a primitive urogenital sinus. http://purl.obolibrary.org/obo/CL_0009018 lymphocyte of large intestine lamina propria http://purl.obolibrary.org/obo/CL_0000542 lymphocyte A lymphocyte that resides in the lamina propria of the large intestine. http://purl.obolibrary.org/obo/UBERON_0009845 urogenital sinus mesenchyme http://purl.obolibrary.org/obo/UBERON_0003104 mesenchyme Mesenchyme that surrounds primitive urogenital sinus. http://purl.obolibrary.org/obo/CL_0009019 nephrogenic zone cell http://purl.obolibrary.org/obo/CL_0002681 kidney cortical cell A kidney cortical cell that is part of the nephrogenic zone. http://purl.obolibrary.org/obo/UBERON_0009846 embryonic cloacal epithelium http://purl.obolibrary.org/obo/UBERON_0012481 cloacal epithelium An epithelium that is part of a embryonic cloaca. http://purl.obolibrary.org/obo/CL_0010017 zygote http://purl.obolibrary.org/obo/CL_0000000 cell A zygote in a plant or an animal. http://purl.obolibrary.org/obo/UBERON_0009847 prostate field http://purl.obolibrary.org/obo/UBERON_0007688 anlage A specific region of the urogenital sinus epithelium into the area in which the prostate gland will develop. http://purl.obolibrary.org/obo/CL_0011027 skeletal muscle fibroblast http://purl.obolibrary.org/obo/CL_1001609 muscle fibroblast Any fibroblast that is part of skeletal muscle tissue. http://purl.obolibrary.org/obo/UBERON_0009848 zona limitans intrathalamica http://purl.obolibrary.org/obo/UBERON_0007651 anatomical junction A narrow stripe of cells that lies between the prospective dorsal and ventral thalami. This boundary contains signals that pattern the prethalamic and thalamic territories of the future mid-diencephalon. http://purl.obolibrary.org/obo/CL_0011028 olfactory ensheathing cell http://purl.obolibrary.org/obo/CL_0000125 glial cell A neural-crest derived glial cell that supports the growth and survival of primary olfactory neuroons from the neuroepithelium in the nasal cavity to the brain by encasing large bundles of numerous unmyelinated axons. http://purl.obolibrary.org/obo/UBERON_0009851 border of sublaminar layers S4 and S5 http://purl.obolibrary.org/obo/UBERON_0009740 border between sublaminar layers The intersection of sublaminar layers S4 and S5. http://purl.obolibrary.org/obo/CL_0019020 extrahepatic cholangiocyte http://purl.obolibrary.org/obo/CL_1000488 cholangiocyte An epithelial cell of the extrahepatic bile ducts, including the left and right hepatic duct, common hepatic duct, and common bile duct. They are columnar in shape, and have a large nuclear-to-cytoplasmic ratio relative to small/intrahepatic cholangiocytes. http://purl.obolibrary.org/obo/UBERON_0009852 border of sublaminar layers S2 and S3 http://purl.obolibrary.org/obo/UBERON_0009740 border between sublaminar layers The intersection of sublaminar layers S2 and S3. http://purl.obolibrary.org/obo/CL_0019021 endothelial cell of periportal hepatic sinusoid http://purl.obolibrary.org/obo/CL_1000398 endothelial cell of hepatic sinusoid An endothelial cell found in the periportal region hepatic sinusoid, near the portal triad. The fenestrae of these cells are larger but fewer in number compared with those of endothelial cells near the centrilobular region of the hepatic sinusoid. http://purl.obolibrary.org/obo/UBERON_0009854 digestive tract diverticulum http://purl.obolibrary.org/obo/UBERON_0009856 sac Branch or outpocketing of the digestive tract. http://purl.obolibrary.org/obo/CL_0019022 endothelial cell of pericentral hepatic sinusoid http://purl.obolibrary.org/obo/CL_1000398 endothelial cell of hepatic sinusoid An endothelial cell found in the centrilobular region hepatic sinusoid, near the central vein. The fenestrae of these cells are smaller but more numerous compared with those of endothelial cells near the periportal region of the hepatic sinusoid. http://purl.obolibrary.org/obo/UBERON_0009859 endosteum http://purl.obolibrary.org/obo/UBERON_0000158 membranous layer A thin layer of connective tissue that lines the surface of the bony tissue that forms the medullary cavity of long bones. http://purl.obolibrary.org/obo/CL_0019026 periportal region hepatocyte http://purl.obolibrary.org/obo/CL_0000182 hepatocyte Any hepatocyte that is part of the liver lobule periportal region. These cells are primarily involved in oxidative energy metabolism. http://purl.obolibrary.org/obo/UBERON_0009870 zone of stomach http://purl.obolibrary.org/obo/UBERON_0034944 zone of organ A division of the stomach. The stomach can be divided based on mucosal histology (glandular epithelium and gastric glands) and the relative position and type of gastric gland. http://purl.obolibrary.org/obo/CL_0019028 midzonal region hepatocyte http://purl.obolibrary.org/obo/CL_0000182 hepatocyte Any hepatocyte that is part of the liver lobule midzonal region. These cells have mixed functionality in comparison with those in the other two regions of the liver lobule. http://purl.obolibrary.org/obo/UBERON_0009871 nephrogenic zone http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure Outer portion of the renal cortex. Site of formation of medullary and cortical elements. http://purl.obolibrary.org/obo/CL_0019029 centrilobular region hepatocyte http://purl.obolibrary.org/obo/CL_0000182 hepatocyte Any hepatocyte that is part of the liver lobule centrilobular region. These cells are the primary location for the biotransformation of drugs. http://purl.obolibrary.org/obo/UBERON_0009877 metapodium region http://purl.obolibrary.org/obo/UBERON_0002529 limb segment Intermediate segment of the autopod, between the mesopodial region and and acropodial region. Examples: metacarpal region, metatarsal region. http://purl.obolibrary.org/obo/CL_4006000 fibroblast of breast http://purl.obolibrary.org/obo/CL_0000057 fibroblast A fibroblast that is part of the breast. http://purl.obolibrary.org/obo/UBERON_0009878 mesopodial skeleton http://purl.obolibrary.org/obo/UBERON_0010712 limb skeleton subdivision The collection of all skeletal elements in a mesopodium. Examples: the tarsal skeleton, the carpal skeleton. http://purl.obolibrary.org/obo/CL_4006001 fibroblast of skin of scalp http://purl.obolibrary.org/obo/CL_0002620 skin fibroblast A fibroblast that is part of the skin of scalp. http://purl.obolibrary.org/obo/UBERON_0009879 tarsal skeleton http://purl.obolibrary.org/obo/UBERON_0009878 mesopodial skeleton Subdivision of skeleton that consists of endochondral elements distal to the zeugopodial skeletal elements which constitute the proximal region of the posterior autopod skeleton[PHENOSCAPE:ad]. http://purl.obolibrary.org/obo/CL_4023000 beta motor neuron http://purl.obolibrary.org/obo/CL_0008039 lower motor neuron A motor neuron that innervates both intrafusal and extrafusal muscle fibers. Low abundancy. They control both muscle contraction and responsiveness of the sensory feedback from muscle spindles. http://purl.obolibrary.org/obo/UBERON_0009880 carpal skeleton http://purl.obolibrary.org/obo/UBERON_0009878 mesopodial skeleton Subdivision of skeleton that consists of the endochondral elements distal to the anterior limb/fin zeugopodial skeletal elements which constitute the proximal region of the anterior autopod skeleton[PHENOSCAPE:ad]. http://purl.obolibrary.org/obo/CL_4023001 static beta motor neuron http://purl.obolibrary.org/obo/CL_4023000 beta motor neuron A beta motor neuron that innervates nuclear chain fibers. http://purl.obolibrary.org/obo/UBERON_0009882 anal column http://purl.obolibrary.org/obo/UBERON_0034944 zone of organ One of a number of vertical folds, produced by an infolding of the mucous membrane and some of the muscular tissue in the upper half of the lumen of the anal canal[WP]. http://purl.obolibrary.org/obo/CL_4023002 dynamic beta motor neuron http://purl.obolibrary.org/obo/CL_4023000 beta motor neuron A beta motor neuron that innervates the nuclear bag fibers of muscle spindles. http://purl.obolibrary.org/obo/UBERON_0009883 medullary ray http://purl.obolibrary.org/obo/UBERON_0000064 organ part A renal, cortical lobule, consisting of the ascending or descending limbs of the loop of Henle or of the collecting tubules; medullary rays are regions where parallel arrays of straight tubules travel perpendicular to the capsule and extend from the cortex to the medulla. http://purl.obolibrary.org/obo/CL_4023003 nuclear chain fiber http://purl.obolibrary.org/obo/CL_0008047 intrafusal muscle fiber A type of intrafusal muscle fiber that has nuclei arranged in a linear row. Unlike nuclear bag fibers, the equatorial region of these fibers (in the centre of the spindle) is not expanded. These fibers are responsible for the detection of changes in muscle length. They are innervated by static gamma motor neurons and are principally associated with type II sensory fibers. http://purl.obolibrary.org/obo/UBERON_0009885 interlobar artery http://purl.obolibrary.org/obo/UBERON_0001637 artery An artery that supplies a renal lobe. http://purl.obolibrary.org/obo/CL_4023004 nuclear bag fiber http://purl.obolibrary.org/obo/CL_0008047 intrafusal muscle fiber A type of intrafusal muscle fiber that lies in the center of a muscle spindle. Nuclei are clustered centrally and give the equatorial region a swollen appearance. They are associated with associated with dynamic gamma motor neurons, and the stretching of the equatorial region of the nuclear bag fibers results in an increase in the firing rate of type Ia sensory fibers. http://purl.obolibrary.org/obo/UBERON_0009887 interlobar vein http://purl.obolibrary.org/obo/UBERON_0001638 vein The interlobar veins are veins of the renal circulation which drain the renal lobes. http://purl.obolibrary.org/obo/CL_4023005 dynamic nuclear bag fiber http://purl.obolibrary.org/obo/CL_4023004 nuclear bag fiber A nuclear bag fiber that is sensitive mainly to the rate of change in muscle length. http://purl.obolibrary.org/obo/UBERON_0009889 secondary heart field http://purl.obolibrary.org/obo/UBERON_0007688 anlage A specific region of the lateral mesoderm that will form the majority of the mesodermal component of the right ventricle, arterial pole (outflow tract) and venous pole (inflow tract). http://purl.obolibrary.org/obo/CL_4023006 static nuclear bag fiber http://purl.obolibrary.org/obo/CL_4023004 nuclear bag fiber A nuclear bag fiber that is sensitive only changes in muscle length but not the rate of that change. http://purl.obolibrary.org/obo/UBERON_0009891 facial mesenchyme http://purl.obolibrary.org/obo/UBERON_0005253 head mesenchyme Mesenchyme that is part of a developing face. http://purl.obolibrary.org/obo/UBERON_8410024 intestinal junction http://purl.obolibrary.org/obo/UBERON_1100000 digestive tract junction An anatomical junction between two parts of the intestine. http://purl.obolibrary.org/obo/UBERON_0009906 root of optic nerve http://purl.obolibrary.org/obo/UBERON_0006843 root of cranial nerve A nerve root that extends_fibers_into a nerve connecting eye with brain. http://purl.obolibrary.org/obo/UBERON_1100000 digestive tract junction http://purl.obolibrary.org/obo/UBERON_0007651 anatomical junction An anatomical junction between two parts of the digestive tract. http://purl.obolibrary.org/obo/UBERON_0009912 anatomical lobe http://purl.obolibrary.org/obo/UBERON_0000063 organ subunit A portion of an organ, such as the liver, lung, breast, or brain. http://purl.obolibrary.org/obo/CL_4023055 corticothalamic VAL/VM projecting glutamatergic neuron of the primary motor cortex http://purl.obolibrary.org/obo/CL_2000049 primary motor cortex pyramidal cell A corticothalamic-projecting glutamatergic neuron that is located in L6 and lower L5 of the primary motor cortex, with a pyramidal morphology and mostly untufted apical dendrites terminating in midcortical layers. CT VAL/VM (ventroanterior-ventrolateral complex/ventromedial nucleus) cells have a near tonic firing pattern and are distinguished from L6 IT neurons by a lower inter-spike interval adaptation index. http://purl.obolibrary.org/obo/UBERON_0009913 renal lobe http://purl.obolibrary.org/obo/UBERON_0009912 anatomical lobe The portion of a kidney consisting of a renal medullary pyramid and the renal cortex above it[MP]. It is composed of many renal lobules[WP]. http://purl.obolibrary.org/obo/GO_0140650 radial glia-guided pyramidal neuron migration http://purl.obolibrary.org/obo/GO_0001764 neuron migration The radial migration of a pyramidal neuron along radial glial cells. http://purl.obolibrary.org/obo/UBERON_0009914 renal lobule http://purl.obolibrary.org/obo/UBERON_0009911 lobule The portion of a renal lobe consisting of nephrons grouped around a single medullary ray and draining into a single collecting duct; human kidneys have multilobular, multipapillary architecture while mice and rats have unilobular, unipapillary kidneys. http://purl.obolibrary.org/obo/CL_0009032 B cell of appendix http://purl.obolibrary.org/obo/CL_0000236 B cell A B cell that is located in a vermiform appendix. http://purl.obolibrary.org/obo/UBERON_0009916 wall of ureter http://purl.obolibrary.org/obo/UBERON_0000060 anatomical wall An anatomical wall that is part of a ureter. http://purl.obolibrary.org/obo/CL_4023077 bitufted neuron http://purl.obolibrary.org/obo/CL_0000099 interneuron A type of interneuron that has two clusters of dendritic branches that originate directly from the soma and extend in opposite directions and axons that form a plexus which spreads widely. Compared to bipolar neurons, bitufted neurons have branching that occur close to the soma. http://purl.obolibrary.org/obo/UBERON_0009917 kidney corticomedullary boundary http://purl.obolibrary.org/obo/UBERON_0007651 anatomical junction The region demarcating the renal medulla from the surrounding cortex; end-stage renal failure may be associated with loss of the normal corticomedullary boundary. http://purl.obolibrary.org/obo/CL_4023081 inverted L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (Mmus) http://purl.obolibrary.org/obo/CL_4023092 inverted pyramidal neuron a L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex that has inverted pyramidal morphology. http://purl.obolibrary.org/obo/UBERON_0009918 retrotrapezoid nucleus http://purl.obolibrary.org/obo/UBERON_0007635 nucleus of medulla oblongata The loose collection of neurons that reside in the rostral medulla close to the medullary surface, ventral and immediately caudal of nVII, that are crucial for CO2 sensing in the brain. http://purl.obolibrary.org/obo/CL_4023043 L5/6 near-projecting glutamatergic neuron of the primary motor cortex http://purl.obolibrary.org/obo/CL_4030067 L5/6 near-projecting glutamatergic neuron A transcriptomically distinct near-projecting glutamatergic neuron with a soma found in layer 5/6 of the primary motor cortex. The standard transcriptomic reference data for this cell type can be found on the CellxGene census under the collection: 'Transcriptomic cytoarchitecture reveals principles of human neocortex organization', dataset: 'Supercluster: Deep layer (non-IT) excitatory neurons', Author Categories: 'CrossArea_subclass', cluster L5/6 NP. http://purl.obolibrary.org/obo/UBERON_0009919 ureter smooth muscle http://purl.obolibrary.org/obo/UBERON_0001135 smooth muscle tissue The smooth muscle tissue surrounding the epithelium of the ureter. http://purl.obolibrary.org/obo/CL_4023092 inverted pyramidal neuron http://purl.obolibrary.org/obo/CL_0000598 pyramidal neuron A pyramidal neuron which has an apical tree which is oriented towards the white matter. http://purl.obolibrary.org/obo/UBERON_0009951 main olfactory bulb http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain The main olfactory bulb has a multi-layered cellular architecture. In order from surface to the center the layers are: Glomerular layer, External plexiform layer, Mitral cell layer, Internal plexiform layer, Granule cell layer[WP]. http://purl.obolibrary.org/obo/CL_4023066 horizontal pyramidal neuron http://purl.obolibrary.org/obo/CL_0000598 pyramidal neuron A pyramidal neuron which has an apical tree which is oriented parallel to the pia. This is unlike typical pyramidal neurons which have its apical dendrite aligned vertically. http://purl.obolibrary.org/obo/UBERON_0009953 post-embryonic organism http://purl.obolibrary.org/obo/UBERON_0000468 multicellular organism A multicellular organism that existence_starts_with a post-embryonic stage. http://purl.obolibrary.org/obo/CL_0009052 smooth muscle cell of anorectum http://purl.obolibrary.org/obo/CL_1000279 smooth muscle cell of large intestine A smooth muscle cell that is located in the anorectum. http://purl.obolibrary.org/obo/UBERON_0009954 vomeronasal system http://purl.obolibrary.org/obo/UBERON_0001032 sensory system A vertebrate nasal chemosensory system that is responsible for detecting intraspecific pheromonal cues as well as environmental odorants. http://purl.obolibrary.org/obo/CL_0009054 microfold cell of epithelium proper of anorectum http://purl.obolibrary.org/obo/CL_1000360 microfold cell of epithelium proper of large intestine A microfold cell (M cell) that is part of the anorectum. http://purl.obolibrary.org/obo/UBERON_0009955 neurogenic placode http://purl.obolibrary.org/obo/UBERON_0002546 cranial placode Cranial ectodermal placode with potential to develop into a component of the nervous system, such as nerves or ganglia. http://purl.obolibrary.org/obo/CL_0009059 plasma cell of medullary sinus of lymph node http://purl.obolibrary.org/obo/CL_0000786 plasma cell A plasma cell that is located in the medullary sinus of the lymph node. http://purl.obolibrary.org/obo/UBERON_0009958 bladder lumen http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space An anatomical space that is enclosed by a urinary bladder. http://purl.obolibrary.org/obo/CL_0009061 intestinal crypt stem cell of anorectum http://purl.obolibrary.org/obo/CL_0009016 intestinal crypt stem cell of large intestine An intestinal crypt stem cell that is located in the anorectum. http://purl.obolibrary.org/obo/UBERON_0009960 esophagus smooth muscle circular layer http://purl.obolibrary.org/obo/UBERON_0012368 circular muscle layer of muscular coat A circular muscle layer of muscular coat that is part of a esophagus. http://purl.obolibrary.org/obo/CL_0009111 centrocyte http://purl.obolibrary.org/obo/CL_0000844 germinal center B cell A germinal center B cell found in a lymph node germinal center light zone. http://purl.obolibrary.org/obo/UBERON_0009966 internodal tract http://purl.obolibrary.org/obo/UBERON_0010131 conducting tissue of heart A conducting pathway in the conducting tissue of heart through which electrical activity spreads from the SA node to the AV node. http://purl.obolibrary.org/obo/CL_0017009 Axl+ dendritic cell, human http://purl.obolibrary.org/obo/CL_0001056 dendritic cell, human A human dendritic cell that expresses the AXL and SIGLEC6 genes. http://purl.obolibrary.org/obo/UBERON_0009970 epithelium of pancreatic duct http://purl.obolibrary.org/obo/UBERON_0034969 epithelial layer of duct An epithelium that is part of a pancreatic duct. http://purl.obolibrary.org/obo/CL_0003025 retinal ganglion cell C3 http://purl.obolibrary.org/obo/CL_0003024 retinal ganglion cell C inner A retinal ganglion cell C inner that has sparse dendritic density, and large dendritic field. http://purl.obolibrary.org/obo/UBERON_0009971 principal gastric gland http://purl.obolibrary.org/obo/UBERON_0000325 gastric gland One of the gastric glands that secretes the hydrochloric acid of the gastric juice[Stedman's]. http://purl.obolibrary.org/obo/CL_0003038 M7-OFF retinal ganglion cell http://purl.obolibrary.org/obo/CL_4023033 OFF retinal ganglion cell An M7 retinal ganglion cells with synaptic terminals in S2 and is depolarized by decreased illumination of their receptive field center http://purl.obolibrary.org/obo/UBERON_0009972 ureteropelvic junction http://purl.obolibrary.org/obo/UBERON_0007651 anatomical junction The junction between the ureter and the renal pelvis of the kidney. http://purl.obolibrary.org/obo/CL_0004246 monostratified cell http://purl.obolibrary.org/obo/CL_2000029 central nervous system neuron A central nervous system neuron that stratifies at one and only one location. http://purl.obolibrary.org/obo/UBERON_0009973 ureterovesical junction http://purl.obolibrary.org/obo/UBERON_0007651 anatomical junction The valve-like structure found at the site of entry of the ureter into the urinary bladder, normally displays an oblique angulation through the detrusor to avoid reflux of urine up the ureters and the kidney. http://purl.obolibrary.org/obo/CL_0003033 M4 retinal ganglion cell http://purl.obolibrary.org/obo/CL_0000740 retinal ganglion cell A monostratified retinal ganglion cell that has a large soma, a medium dendritic field with post synaptic terminals in sublaminar layer S3. http://purl.obolibrary.org/obo/UBERON_0009974 lumen of Rathke's pouch http://purl.obolibrary.org/obo/UBERON_0007473 lumen of epithelial sac An anatomical cavity that surrounded_by a Rathke's pouch. http://purl.obolibrary.org/obo/CL_0004230 diffuse bistratified amacrine cell http://purl.obolibrary.org/obo/CL_0004251 narrow field retinal amacrine cell A bistratified amacrine cell with a small dendritic field that has post-synaptic terminals in S1 and the border of S1-S2, and termination of a second arbor within the border of S2-S3 and S3. http://purl.obolibrary.org/obo/UBERON_0010000 multicellular anatomical structure http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure An anatomical structure that has more than one cell as a part. http://purl.obolibrary.org/obo/UBERON_8480024 skin of sacral region http://purl.obolibrary.org/obo/UBERON_0001415 skin of pelvis A zone of skin that is part of the sacral region. http://purl.obolibrary.org/obo/UBERON_0010001 cell cluster organ http://purl.obolibrary.org/obo/UBERON_0034922 cell cluster A small cluster of cells of various types which form a discrete structure, largely delimited by a morphological boundary and whose components work together to make the whole structure capable of a specific function. http://purl.obolibrary.org/obo/CL_4030034 respiratory tract multiciliated cell http://purl.obolibrary.org/obo/CL_0005012 multiciliated epithelial cell A multiciliated epithelial cell located in the respiratory tract epithelium, characterized by a columnar shape and motile cilia on its apical surface. This cell develops through a highly orchestrated process, transitioning from a basal progenitor via an intermediate deuterosomal cell stage that generates centrioles essential for ciliogenesis. http://purl.obolibrary.org/obo/UBERON_0010005 placental labyrinth villous http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure The vascularized and branched structures arising from the rodent trophoblast-derived epithelium that allow an increase its surface area for the efficient exchange of nutrients and wastes between the maternal and fetal circulation. http://purl.obolibrary.org/obo/CL_4030035 dental pulp stem cell http://purl.obolibrary.org/obo/CL_0002148 dental pulp cell A dental pulp cell that possesses stem-cell-like qualities, including self-renewal capability and multi-lineage differentiation. http://purl.obolibrary.org/obo/UBERON_0010009 aggregate regional part of brain http://purl.obolibrary.org/obo/UBERON_0034923 disconnected anatomical group A regional part of brain consisting of multiple brain regions that are not related through a simple volummetric part of hierarchy, e.g., basal ganglia[NIF]. http://purl.obolibrary.org/obo/CL_4030036 early spermatid http://purl.obolibrary.org/obo/CL_0000018 spermatid A spermatid in an early stage of maturation that has a round morphology and is transcriptionally active. http://purl.obolibrary.org/obo/UBERON_0010020 tubotympanic recess epithelium http://purl.obolibrary.org/obo/UBERON_0015813 middle ear epithelium The dorsal portion of the embryonic first endodermal pharyngeal pouch; it develops into the middle ear cavity. http://purl.obolibrary.org/obo/CL_4030037 late spermatid http://purl.obolibrary.org/obo/CL_0000018 spermatid A spermatid in a late stage of maturation that has an elongated morphology and is transcriptionally inert when the acrosome is fully developed. http://purl.obolibrary.org/obo/UBERON_0010031 6th arch mesenchyme http://purl.obolibrary.org/obo/UBERON_0009494 pharyngeal arch mesenchymal region Mesenchyme that is part of a pharyngeal arch 6. http://purl.obolibrary.org/obo/CL_4030040 endometrial multiciliated epithelial cell http://purl.obolibrary.org/obo/CL_0005012 multiciliated epithelial cell A multi-ciliated cell of the endometrial epithelium. This cell is characterized by the presence of 9+2 motile cilia on its apical surface, which facilitates the movement of mucus across the endometrial surface. http://purl.obolibrary.org/obo/UBERON_0010032 anterior part of tongue http://purl.obolibrary.org/obo/UBERON_0000064 organ part The portion of the tongue in front of the terminal sulcus. At the apex, thin and narrow, it is directed forward against the lingual surfaces of the lower incisor teeth. It is derived primarily from the first pharyngeal arch. http://purl.obolibrary.org/obo/CL_4030041 luminal endometrial multiciliated epithelial cell http://purl.obolibrary.org/obo/CL_4030040 endometrial multiciliated epithelial cell A ciliated cell of the endometrial luminal epithelium. This cell is characterized by the presence of motile cilia on its apical surface. http://purl.obolibrary.org/obo/UBERON_0010038 fundic gastric gland http://purl.obolibrary.org/obo/UBERON_0000414 mucous gland The fundus glands (or fundic glands, or gastric glands) are found in the body and fundus of the stomach. They are simple tubes, two or more of which open into a single duct. http://purl.obolibrary.org/obo/CL_4030042 glandular endometrial multiciliated epithelial cell http://purl.obolibrary.org/obo/CL_0009084 glandular epithelial cell of endometrium A ciliated cell of the endometrial glandular epithelium. This cell is characterized by the presence of motile cilia on its apical surface. http://purl.obolibrary.org/obo/UBERON_0010039 food storage organ http://purl.obolibrary.org/obo/UBERON_0013765 digestive system element An organ of the digestive tract that is capable of retaining and storing food. http://purl.obolibrary.org/obo/CL_4033003 myoepithelial cell of bronchus submucosal gland http://purl.obolibrary.org/obo/CL_0002328 bronchial epithelial cell A(n) myoepithelial cell that is part of a(n) bronchus submucosal gland. http://purl.obolibrary.org/obo/UBERON_0010042 1st arch mesenchyme http://purl.obolibrary.org/obo/UBERON_0009494 pharyngeal arch mesenchymal region Mesenchyme that is part of a pharyngeal arch 1. http://purl.obolibrary.org/obo/CL_4033004 smooth muscle cell of taenia coli http://purl.obolibrary.org/obo/CL_1000279 smooth muscle cell of large intestine A(n) smooth muscle cell that is part of a(n) taenia coli. http://purl.obolibrary.org/obo/UBERON_0010045 1st arch maxillary mesenchyme http://purl.obolibrary.org/obo/UBERON_0010042 1st arch mesenchyme Mesenchyme that is part of a 1st arch maxillary component. http://purl.obolibrary.org/obo/CL_4033005 serous secreting cell of bronchus submucosal gland http://purl.obolibrary.org/obo/CL_0019001 tracheobronchial serous cell A(n) serous secreting cell that is part of a(n) bronchus submucosal gland. http://purl.obolibrary.org/obo/UBERON_0010046 entire pharyngeal arch associated mesenchyme http://purl.obolibrary.org/obo/UBERON_0007524 dense mesenchyme tissue The sum total of mesenchymal tissue in the pharyngeal arch region. Pharyngeal mesenchyme is undifferentiated, loose connective tissue derived mostly from mesoderm, and also contains ectodermally derived neural crest cells. http://purl.obolibrary.org/obo/CL_4033006 endothelial cell of efferent lymphatic vessel http://purl.obolibrary.org/obo/CL_0002138 endothelial cell of lymphatic vessel A(n) endothelial cell that is part of a(n) efferent lymphatic vessel. http://purl.obolibrary.org/obo/UBERON_0010047 oral gland http://purl.obolibrary.org/obo/UBERON_0003408 gland of digestive tract Gland of the epithelium lining the oral cavity. The most common are the salivary glands. http://purl.obolibrary.org/obo/CL_4033007 brush cell of epithelium of lobar bronchus http://purl.obolibrary.org/obo/CL_0002208 brush cell of bronchus A(n) brush cell that is part of a(n) epithelium of lobar bronchus. http://purl.obolibrary.org/obo/UBERON_0010052 mucosa of dorsum of tongue http://purl.obolibrary.org/obo/UBERON_0005020 mucosa of tongue A mucosa that is part of a dorsum of tongue. http://purl.obolibrary.org/obo/CL_4033008 vein endothelial cell of respiratory system http://purl.obolibrary.org/obo/CL_0002543 vein endothelial cell A(n) vein endothelial cell that is part of a(n) respiratory system. http://purl.obolibrary.org/obo/UBERON_0010056 future tongue http://purl.obolibrary.org/obo/UBERON_0013765 digestive system element A compound organ that has the potential to develop into a tongue. http://purl.obolibrary.org/obo/CL_4033009 goblet cell of epithelium of lobar bronchus http://purl.obolibrary.org/obo/CL_1000312 bronchial goblet cell A(n) goblet cell that is part of a(n) epithelium of lobar bronchus. http://purl.obolibrary.org/obo/UBERON_0010060 pharyngeal opening of pharyngotympanic tube http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space On the lateral wall of the nasal part of the pharynx is the pharyngeal opening of auditory tube (pharyngeal ostium), somewhat triangular in shape, and bounded behind by a firm prominence, the torus or cushion, caused by the medial end of the cartilage of the tube which elevates the mucous membrane. http://purl.obolibrary.org/obo/CL_4033010 neuroendocrine cell of epithelium of lobar bronchus http://purl.obolibrary.org/obo/CL_0008055 respiratory tract secretory epithelial cell A(n) neuroendocrine cell that is part of a(n) epithelium of lobar bronchus. http://purl.obolibrary.org/obo/UBERON_0010064 open anatomical space http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space An anatomical space with at least one opening to another space or the exterior. http://purl.obolibrary.org/obo/CL_4033011 smooth muscle cell of large intestine smooth muscle circular layer http://purl.obolibrary.org/obo/CL_1000279 smooth muscle cell of large intestine A(n) smooth muscle cell that is part of a(n) large intestine smooth muscle circular layer. http://purl.obolibrary.org/obo/UBERON_0010069 outer epithelial layer of tympanic membrane http://purl.obolibrary.org/obo/UBERON_0015814 outer ear epithelium A portion of the external acoustic meatus epithelium which makes up the outer (cuticular) layer of the tympanic membrane. http://purl.obolibrary.org/obo/CL_4033012 smooth muscle cell of large intestine smooth muscle longitudinal layer http://purl.obolibrary.org/obo/CL_1000279 smooth muscle cell of large intestine A(n) smooth muscle cell that is part of a(n) large intestine smooth muscle longitudinal layer. http://purl.obolibrary.org/obo/UBERON_0010070 intermediate layer of tympanic membrane http://purl.obolibrary.org/obo/UBERON_0010071 layer of tympanic membrane The intermediate fibrous layer of the tympanic membrane. http://purl.obolibrary.org/obo/CL_4033037 mucus secreting cell of tracheobronchial tree submucosal gland http://purl.obolibrary.org/obo/CL_0008055 respiratory tract secretory epithelial cell A mucus secreting cell of a submucosal gland of the tracheobronchial tree. http://purl.obolibrary.org/obo/UBERON_0010074 chromaffin system http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision Organ system subdivision that consists primarily of chromaffin cells and their supporting structures. http://purl.obolibrary.org/obo/CL_4030057 eccentric medium spiny neuron http://purl.obolibrary.org/obo/CL_1001474 medium spiny neuron A medium spiny neuron that exhibits transcriptional divergence from direct and indirect spiny projection neurons, for example, enrichment in Casz1, Otof, Cacng5 and Pcdh8 noted in mice. Whilst in general medium spiny neurons have been found to be differentially distributed across the basal ganglia, the eccentric medium spiny neuron cell type has been found to be more evenly distributed throughout cerebral nuclei. http://purl.obolibrary.org/obo/UBERON_0010075 sacral neural crest http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue One of the 5 distinct and partially overlapping functional domains of the premigratory neural crest. The vagal and sacral neural crest cells develop into the ganglia of the enteric nervous system, also known as the parasympathetic ganglia. http://purl.obolibrary.org/obo/GO_0141188 nucleic acid catabolic process http://purl.obolibrary.org/obo/GO_0009057 macromolecule catabolic process The cellular DNA metabolic process resulting in the breakdown of a nucleic acid. http://purl.obolibrary.org/obo/UBERON_0010077 cuboidal epithelium http://purl.obolibrary.org/obo/UBERON_0000483 epithelium An epithelium consisting of cuboidal epithelial cells. http://purl.obolibrary.org/obo/GO_0170055 lipid transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity Enables the transfer of a lipid from one side of a membrane to the other. http://purl.obolibrary.org/obo/UBERON_0010081 future common hepatic duct http://purl.obolibrary.org/obo/UBERON_0034932 epithelium of biliary system An extrahepatic bile duct that has the potential to develop into a common hepatic duct. http://purl.obolibrary.org/obo/CL_4307091 OPC NN_2 oligodendrocyte precursor cell (Mmus) http://purl.obolibrary.org/obo/CL_4300366 oligodendrocyte precursor cell (Mmus) A oligodendrocyte precursor cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Pdgfra (Mmus), Cenpf (Mmus), Cenpa (Mmus). It is distinguished from other OPC NN cells by expression of Cenpa. These cells are located in the Isocortex, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5271 OPC NN_2. http://purl.obolibrary.org/obo/UBERON_0010083 future dermis http://purl.obolibrary.org/obo/UBERON_0003104 mesenchyme Mesenchyme that has the potential to develop into a dermis. http://purl.obolibrary.org/obo/GO_0110053 regulation of actin filament organization http://purl.obolibrary.org/obo/GO_0032956 regulation of actin cytoskeleton organization Any process that modulates the frequency, rate or extent of actin filament organization. http://purl.obolibrary.org/obo/UBERON_0010084 future diaphragm http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure A structure that will develop into a diaphragm. http://purl.obolibrary.org/obo/GO_0120116 glucagon processing http://purl.obolibrary.org/obo/GO_0016486 peptide hormone processing The formation of mature glucagon by proteolysis of the precursor proglucagon. http://purl.obolibrary.org/obo/UBERON_0010091 future hindbrain meninx http://purl.obolibrary.org/obo/UBERON_0007645 future meninx A multi-tissue structure that has the potential to develop into a meninx of hindbrain. http://purl.obolibrary.org/obo/PATO_0045021 normal flexibility http://purl.obolibrary.org/obo/PATO_0045001 normal object quality A flexibility which is relatively normal or average. http://purl.obolibrary.org/obo/UBERON_0010092 future metencephalon http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure A developing anatomical structure that has the potential to develop into a metencephalon. http://purl.obolibrary.org/obo/PATO_0045081 normal viscosity http://purl.obolibrary.org/obo/PATO_0045001 normal object quality A viscosity which is relatively normal or average http://purl.obolibrary.org/obo/GO_0110088 hippocampal neuron apoptotic process http://purl.obolibrary.org/obo/GO_0051402 neuron apoptotic process Any apoptotic process that occurs in a hippocampal neuron. http://purl.obolibrary.org/obo/UBERON_0010096 future myelencephalon http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure A developing anatomical structure that has the potential to develop into a myelencephalon. http://purl.obolibrary.org/obo/GO_0110089 regulation of hippocampal neuron apoptotic process http://purl.obolibrary.org/obo/GO_0043523 regulation of neuron apoptotic process Any process that modulates the occurrence or rate of cell death by apoptotic process in hippocampal neurons. http://purl.obolibrary.org/obo/UBERON_0010123 future facial nucleus http://purl.obolibrary.org/obo/UBERON_0002020 gray matter A gray matter that has the potential to develop into a facial nucleus. http://purl.obolibrary.org/obo/GO_0110090 positive regulation of hippocampal neuron apoptotic process http://purl.obolibrary.org/obo/GO_0110089 regulation of hippocampal neuron apoptotic process Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process in hippocampal neurons. http://purl.obolibrary.org/obo/UBERON_0010125 future superior salivatory nucleus http://purl.obolibrary.org/obo/UBERON_0002020 gray matter A gray matter that has the potential to develop into a superior salivatory nucleus. http://purl.obolibrary.org/obo/GO_0110091 negative regulation of hippocampal neuron apoptotic process http://purl.obolibrary.org/obo/GO_0110089 regulation of hippocampal neuron apoptotic process Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process in hippocampal neurons. http://purl.obolibrary.org/obo/UBERON_0010128 future pterygopalatine ganglion http://purl.obolibrary.org/obo/UBERON_0001808 parasympathetic ganglion A ganglion that has the potential to develop into a pterygopalatine ganglion. http://purl.obolibrary.org/obo/PR_000036947 T-cell surface glycoprotein CD1 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A T-cell surface glycoprotein CD1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0010129 femur cartilage element http://purl.obolibrary.org/obo/UBERON_0015052 femur endochondral element A femur endochondral element that is composed primarily of cartilage tissue. http://purl.obolibrary.org/obo/GO_0062033 positive regulation of mitotic sister chromatid segregation http://purl.obolibrary.org/obo/GO_0033047 regulation of mitotic sister chromatid segregation Any process that starts or increases the frequency, rate or extent of sister chromatid segregation during mitosis. http://purl.obolibrary.org/obo/UBERON_0010130 embryonic autopod plate http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure The distal elements of the developing limb of vertebrates that will give rise to the autopod (e.g. manus, pes, paw). http://purl.obolibrary.org/obo/GO_0150044 regulation of postsynaptic dense core vesicle exocytosis http://purl.obolibrary.org/obo/GO_1905413 regulation of dense core granule exocytosis Any process that modulates the frequency, rate or extent of postsynaptic dense core vesicle exocytosis. http://purl.obolibrary.org/obo/UBERON_0010131 conducting tissue of heart http://purl.obolibrary.org/obo/UBERON_0001133 cardiac muscle tissue Any portion of cardiac muscle tissue that is part of the conducting system of heart or the Purkinje fibers. http://purl.obolibrary.org/obo/GO_0150045 regulation of synaptic signaling by nitric oxide http://purl.obolibrary.org/obo/GO_0023051 regulation of signaling Any process that modulates the frequency, rate or extent of synaptic signaling by nitric oxide. http://purl.obolibrary.org/obo/UBERON_0010133 neuroendocrine gland http://purl.obolibrary.org/obo/UBERON_0002368 endocrine gland Any of the organized aggregations of cells that function as secretory or excretory organs and that release hormones in response to neural stimuli. http://purl.obolibrary.org/obo/GO_0062094 stomach development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the stomach over time, from its formation to the mature structure. The stomach is an expanded region of the vertebrate alimentary tract that serves as a food storage compartment and digestive organ. http://purl.obolibrary.org/obo/UBERON_0010134 secretory circumventricular organ http://purl.obolibrary.org/obo/UBERON_0010133 neuroendocrine gland A circumventricular organ that is capable of secreting substances into the cerebrospinal fluid. http://purl.obolibrary.org/obo/CL_3000000 ciliated epithelial cell of esophagus http://purl.obolibrary.org/obo/CL_0002252 epithelial cell of esophagus A ciliated epithelial cell of the esophagus. http://purl.obolibrary.org/obo/UBERON_0010135 sensory circumventricular organ http://purl.obolibrary.org/obo/UBERON_0005408 circumventricular organ A circumventricular organ that is capable of monitoring the levels of substances to the cerebrospinal fluid. http://purl.obolibrary.org/obo/CL_3000001 Hofbauer cell http://purl.obolibrary.org/obo/CL_4033087 placental resident macrophage A tissue-resident macrophage that is part of the placenta. A Hofbauer cell expresses high levels of growth factors and metalloproteinases that support vasculogenesis, angiogenesis, branching morphogenesis and tissue remodeling. A Hofbauer cell has a fetal origin, is found in the villous stroma, chorion, and amnion, and is present throughout pregnancy. http://purl.obolibrary.org/obo/UBERON_0010136 epithelial sheet http://purl.obolibrary.org/obo/UBERON_0000483 epithelium An epithelial sheet is a flat surface consisting of closely packed epithelial cells. http://purl.obolibrary.org/obo/CL_3000002 sympathetic noradrenergic neuron http://purl.obolibrary.org/obo/CL_0008025 noradrenergic neuron Sympathetic noradrenergic neuron. http://purl.obolibrary.org/obo/UBERON_0010141 primitive sex cord of indifferent gonad http://purl.obolibrary.org/obo/UBERON_0005295 sex cord A sex cord that is part of a indifferent gonad. http://purl.obolibrary.org/obo/CL_3000003 sympathetic cholinergic neuron http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron A type of autonomic neuron that releases acetylcholine. http://purl.obolibrary.org/obo/UBERON_0010143 seminal vesicle fluid http://purl.obolibrary.org/obo/UBERON_0006530 seminal fluid A bodily secretion that is produced by a seminal vesicle. http://purl.obolibrary.org/obo/CL_3000004 peripheral sensory neuron http://purl.obolibrary.org/obo/CL_2000032 peripheral nervous system neuron A neuron type that is located in a peripheral nervous system and it transmits sensory information from the peripheral (PNS) to the central nervous system (CNS). A sensory neuron converts physical (light, sound, touch) or chemical (such as taste and smell) stimuli into an electrical signal through a process known as sensory transduction. The function of a sensory neuron is to carry informations from the external environment and internal body conditions to the central nervous system for further processing. http://purl.obolibrary.org/obo/UBERON_0010147 male accessory sex gland http://purl.obolibrary.org/obo/UBERON_0005399 male reproductive gland Any gland, other than the gonad, associated with the genital tract, such as the ampulla of the ductus deferens and the bulbourethral, prostate and vesicular glands of the male. http://purl.obolibrary.org/obo/UBERON_0010152 skin mucus http://purl.obolibrary.org/obo/UBERON_0000912 mucus A mucous secretion that is produced by glands in the epidermis. http://purl.obolibrary.org/obo/UBERON_0037144 wall of heart http://purl.obolibrary.org/obo/UBERON_0000060 anatomical wall Wall of organ which has as its parts the endocardium, myocardium , epicardium, and the cardiac septum, surrounded by the pericardial sac proper and is continuous with the walls of the systemic and pulmonary arterial and venous trees. http://purl.obolibrary.org/obo/UBERON_0010156 sphenofrontal suture http://purl.obolibrary.org/obo/UBERON_0003685 cranial suture The Sphenofrontal suture is the cranial suture between the sphenoid bone and the frontal bone. http://purl.obolibrary.org/obo/PATO_0070019 untufted pyramidal morphology http://purl.obolibrary.org/obo/PATO_0070017 standard pyramidal morphology A pyramidal cell morphology that inheres in neurons which lack a clear tuft formation but extend to large radial distances. http://purl.obolibrary.org/obo/UBERON_0010160 lumen of lymphatic vessel http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space An anatomical cavity that surrounded_by a lymphatic vessel. http://purl.obolibrary.org/obo/PATO_0070012 bitufted cell morphology http://purl.obolibrary.org/obo/PATO_0070027 bitufted dendrite cell morphology A cell morphology that inheres in neurons which have two clusters of primary dendrites that originate directly and extend from opposite ends of the soma, and axons that form a plexus which spreads widely. Compared to the narrow vertical axonal projection of bipolar morphology, and the 'horse-tail' axonal cluster of double boquet cells, bitufted morphology has wide horizontal axonal spans, and branching that occur close to the soma. Their vertical projection is also less extensive and crosses mostly to neighboring layers. http://purl.obolibrary.org/obo/UBERON_0010161 lumen of blood vessel http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space An anatomical cavity that surrounded_by a blood vessel. http://purl.obolibrary.org/obo/PATO_0010006 cell morphology http://purl.obolibrary.org/obo/PATO_0000051 morphology A quality of a single cell inhering in the bearer by virtue of the bearer's size or shape or structure. http://purl.obolibrary.org/obo/UBERON_0010162 post-anal tail tip http://purl.obolibrary.org/obo/UBERON_0011676 subdivision of organism along main body axis The distal end of the tail. http://purl.obolibrary.org/obo/PATO_0070010 stellate morphology http://purl.obolibrary.org/obo/PATO_0070026 multipolar neuron morphology A cell morphology that inheres in neurons that have dendritic processes radiating from the cell body forming a star-like shape. http://purl.obolibrary.org/obo/UBERON_0010164 collection of hairs http://purl.obolibrary.org/obo/UBERON_0034925 anatomical collection An anatomical cluster that composed_primarily_of a strand of hair. http://purl.obolibrary.org/obo/CL_0009033 plasma cell of appendix http://purl.obolibrary.org/obo/CL_0000786 plasma cell A plasma cell that is located in a vermiform appendix. http://purl.obolibrary.org/obo/UBERON_0010165 collection of hair on face http://purl.obolibrary.org/obo/UBERON_0014382 collection of hairs on head or neck A collection of hairs that is part of a face. http://purl.obolibrary.org/obo/CL_0009036 appendix macrophage http://purl.obolibrary.org/obo/CL_0000235 macrophage A macrophage located in the vermiform appendix. http://purl.obolibrary.org/obo/UBERON_0010171 strand of hair of face http://purl.obolibrary.org/obo/UBERON_0016446 hair of head A strand of hair that is part of a face. http://purl.obolibrary.org/obo/CL_0009030 enteroendocrine cell of appendix http://purl.obolibrary.org/obo/CL_1001516 intestinal enteroendocrine cell An intestinal enteroendocrine cell that is located in a vermiform appendix. http://purl.obolibrary.org/obo/UBERON_0010183 liver trabecula http://purl.obolibrary.org/obo/UBERON_0000440 trabecula A trabecula that is part of a liver. http://purl.obolibrary.org/obo/CL_4023054 mesothelial fibroblast http://purl.obolibrary.org/obo/CL_0000057 fibroblast A mesothelial cell that has undergone mesothelial-to-mesenchymal transition (MMT) to become a fibroblast cell. http://purl.obolibrary.org/obo/UBERON_0010186 male urethral gland http://purl.obolibrary.org/obo/UBERON_0001338 urethral gland Any of the numerous small mucous-secreting glands located in the wall of the penile urethra. http://purl.obolibrary.org/obo/CL_4023048 L4/5 intratelencephalic projecting glutamatergic neuron of the primary motor cortex http://purl.obolibrary.org/obo/CL_4030062 L4/5 intratelencephalic projecting glutamatergic neuron An intratelencephalic-projecting glutamatergic with a soma located in upper L5 of the primary motor cortex. These cells have thin untufted apical dendrites. http://purl.obolibrary.org/obo/UBERON_0010187 female urethral gland http://purl.obolibrary.org/obo/UBERON_0001338 urethral gland An urethral gland that is part of a female urethra. http://purl.obolibrary.org/obo/CL_0009013 fetal hepatobiliary progenitor cell http://purl.obolibrary.org/obo/CL_0011026 progenitor cell A progenitor cell with hepatic and biliary lineage potential, identified in mouse and human, and anatomically restricted to the ductal plate of fetal liver. http://purl.obolibrary.org/obo/UBERON_0010188 protuberance http://purl.obolibrary.org/obo/UBERON_0034944 zone of organ A roughly circular bulge in a surface. http://purl.obolibrary.org/obo/CL_0009028 intestinal crypt stem cell of appendix http://purl.obolibrary.org/obo/CL_0009016 intestinal crypt stem cell of large intestine An intestinal crypt stem cell that is located in the vermiform appendix. These stem cells reside at the bottom of crypts in the appendix and are highly proliferative. They either differentiate into transit amplifying cells or self-renew to form new stem cells. http://purl.obolibrary.org/obo/UBERON_0010192 genital artery http://purl.obolibrary.org/obo/UBERON_0012254 abdominal aorta artery One of the laterally paired arteries that supply the gonads. http://purl.obolibrary.org/obo/CL_0009045 B cell of medullary sinus of lymph node http://purl.obolibrary.org/obo/CL_0000236 B cell A B cell found in the lymph node medullary sinus. http://purl.obolibrary.org/obo/UBERON_0010194 hepatic portal system http://purl.obolibrary.org/obo/UBERON_0005806 portal system A portal system that begins in capillaries in the wall of the digestive tract and and runs as the hepatic portal vein to the liver. http://purl.obolibrary.org/obo/CL_0009084 glandular epithelial cell of endometrium http://purl.obolibrary.org/obo/CL_0002149 epithelial cell of uterus An epithelial cell that is part of an endometrium glandular epithelium. http://purl.obolibrary.org/obo/UBERON_0010199 bona-fide anatomical boundary http://purl.obolibrary.org/obo/UBERON_0000466 immaterial anatomical entity An anatomical boundary that corresponds to some physical discontinuity. http://purl.obolibrary.org/obo/CL_0009086 endothelial cell of respiratory system lymphatic vessel http://purl.obolibrary.org/obo/CL_0002138 endothelial cell of lymphatic vessel An endothelial cell that is part of a respiratory system lymphatic vessel. http://purl.obolibrary.org/obo/UBERON_0010202 lateral line http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure The lateral line consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head and body of all fishes and most amphibians. The lateral line develops from cranial ectodermal placodes situated behind the ear and between the eye and ear. http://purl.obolibrary.org/obo/CL_0009087 fused extravillous trophoblast http://purl.obolibrary.org/obo/CL_0008036 extravillous trophoblast An extravillous trophoblast that is polynuclear. http://purl.obolibrary.org/obo/UBERON_0010204 tail vasculature http://purl.obolibrary.org/obo/UBERON_0002049 vasculature A vasculature that is part of a post-anal tail. http://purl.obolibrary.org/obo/CL_0009092 endothelial cell of placenta http://purl.obolibrary.org/obo/CL_0000115 endothelial cell An endothelial cell that is part of a placenta. http://purl.obolibrary.org/obo/UBERON_0010210 blood clot http://purl.obolibrary.org/obo/UBERON_0000463 organism substance A semisolid gelatinous mass of coagulated blood that consists of red blood cells, white blood cells, and platelets entrapped in a fibrin network. http://purl.obolibrary.org/obo/CL_0009093 smooth muscle cell of placenta http://purl.obolibrary.org/obo/CL_0000192 smooth muscle cell A smooth muscle cell that is part of a placenta. http://purl.obolibrary.org/obo/UBERON_0010212 laryngeal apparatus http://purl.obolibrary.org/obo/UBERON_0034921 multi organ part structure Apparatus located between the lungs and the buccal cavity. This apparatus is composed of a pair of arytenoid cartilages that are supported by the cricoid ring. http://purl.obolibrary.org/obo/CL_0009094 endothelial cell of hepatic portal vein http://purl.obolibrary.org/obo/CL_0002543 vein endothelial cell An endothelial cell that is part of a hepatic portal vein. http://purl.obolibrary.org/obo/UBERON_0010225 thalamic complex http://purl.obolibrary.org/obo/UBERON_0019269 gray matter of diencephalon A nuclear complex which in mammals consists of four parts, the hypothalamus, epithalamus, ventral thalamus, and dorsal thalamus[WP,modified]. http://purl.obolibrary.org/obo/CL_0009095 endothelial cell of uterus http://purl.obolibrary.org/obo/CL_0000115 endothelial cell An endothelial cell that is part of a uterus. http://purl.obolibrary.org/obo/UBERON_0010227 future cardiac atrium http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure Multi-tissue structure that is part of the heart tube and will become the cardiac atrium. http://purl.obolibrary.org/obo/CL_4028003 alveolar capillary type 2 endothelial cell http://purl.obolibrary.org/obo/CL_4028001 pulmonary capillary endothelial cell An alveolar capillary endothelial cell that is located proximally to alveolar capillary type 1 endothelial cells and in close apposition to alveolar type 1 epithelial cells (also known as type I pneumocytes). http://purl.obolibrary.org/obo/UBERON_0010230 eyeball of camera-type eye http://purl.obolibrary.org/obo/UBERON_0000020 sense organ The core globe-shaped component of the camera-type eye. http://purl.obolibrary.org/obo/CL_4028004 alveolar type 1 fibroblast cell http://purl.obolibrary.org/obo/CL_0002553 fibroblast of lung A pulmonary interstitial fibroblast that is part of the alveolus and contains lipid droplets. http://purl.obolibrary.org/obo/UBERON_0010233 stroma of thyroid gland http://purl.obolibrary.org/obo/UBERON_0010313 neural crest-derived structure The connective tissue that supports the lobules and follicles of the thyroid gland. http://purl.obolibrary.org/obo/CL_4028006 alveolar adventitial fibroblast http://purl.obolibrary.org/obo/CL_0002553 fibroblast of lung A pulmonary interstitial fibroblast that is part of the alveolus and localizes to vascular adventitia. http://purl.obolibrary.org/obo/UBERON_0010243 merocrine gland http://purl.obolibrary.org/obo/UBERON_0002365 exocrine gland An exocrine gland whose secretions are excreted via exocytosis from secretory cells into an epithelial-walled duct or ducts and thence onto a bodily surface or into the lumen; the gland releases its product and no part of the gland is lost or damaged. http://purl.obolibrary.org/obo/CL_4030001 stromal cell of thymus http://purl.obolibrary.org/obo/CL_0000499 stromal cell A stromal cell that is part of the thymus. http://purl.obolibrary.org/obo/UBERON_0010252 1st arch mandibular mesenchyme from neural crest http://purl.obolibrary.org/obo/UBERON_0010259 1st arch mesenchyme from neural crest Mesenchyme that develops_from a neural crest and is part of a 1st arch mandibular mesenchyme. http://purl.obolibrary.org/obo/CL_4029003 somatic nurse-like cell http://purl.obolibrary.org/obo/CL_4029001 gamete-nursing cell A gamete-nursing cell that derives from the somatic tissues of the gonad (del Pino, 2021). http://purl.obolibrary.org/obo/UBERON_0010253 1st arch maxillary mesenchyme from neural crest http://purl.obolibrary.org/obo/UBERON_0010259 1st arch mesenchyme from neural crest Mesenchyme that develops_from a neural crest and is part of a 1st arch maxillary mesenchyme. http://purl.obolibrary.org/obo/CL_4029001 gamete-nursing cell http://purl.obolibrary.org/obo/CL_0000000 cell A cell that supports the development of a gamete by providing it cytoplasmic material (including entire organelles) by direct cross-membrane channels (del Pino, 2021). http://purl.obolibrary.org/obo/UBERON_0010254 2nd arch mesenchyme from neural crest http://purl.obolibrary.org/obo/UBERON_0010359 pharyngeal arch mesenchyme from neural crest Mesenchyme that develops_from a neural crest and is part of a 2nd arch mesenchyme. http://purl.obolibrary.org/obo/UBERON_8440011 cortical visual area http://purl.obolibrary.org/obo/UBERON_0035014 functional part of brain The part of the cortex that is responsible for processing visual information. http://purl.obolibrary.org/obo/UBERON_0010255 3rd arch mesenchyme from neural crest http://purl.obolibrary.org/obo/UBERON_0010359 pharyngeal arch mesenchyme from neural crest Mesenchyme that develops_from a neural crest and is part of a 3rd arch mesenchyme. http://purl.obolibrary.org/obo/CL_0004225 spider amacrine cell http://purl.obolibrary.org/obo/CL_0004251 narrow field retinal amacrine cell A broadly stratifying amacrine cell with a small dendritic field, straight dendrites and post-synaptic terminals in S1, S2, and S3. http://purl.obolibrary.org/obo/UBERON_0010256 4th arch mesenchyme from neural crest http://purl.obolibrary.org/obo/UBERON_0010359 pharyngeal arch mesenchyme from neural crest Mesenchyme that develops_from a neural crest and is part of a 4th arch mesenchyme. http://purl.obolibrary.org/obo/CL_0004252 medium field retinal amacrine cell http://purl.obolibrary.org/obo/CL_0000561 amacrine cell An amicrine that has a medium dendritic field. http://purl.obolibrary.org/obo/UBERON_0010257 6th arch mesenchyme from neural crest http://purl.obolibrary.org/obo/UBERON_0010359 pharyngeal arch mesenchyme from neural crest Mesenchyme that develops_from a neural crest and is part of a 6th arch mesenchyme. http://purl.obolibrary.org/obo/CL_0003022 retinal ganglion cell C5 http://purl.obolibrary.org/obo/CL_0003020 retinal ganglion cell C outer A retinal ganglion cell C outer that has medium dendritic density and field size. http://purl.obolibrary.org/obo/UBERON_0010258 mesenchyme from rhombencephalic neural crest http://purl.obolibrary.org/obo/UBERON_0014387 mesenchyme derived from neural crest Mesenchyme that develops_from a rhombencephalon neural crest. http://purl.obolibrary.org/obo/CL_4023074 mammillary body neuron http://purl.obolibrary.org/obo/CL_0012001 neuron of the forebrain A neuron that has its soma located in the mammillary body. http://purl.obolibrary.org/obo/UBERON_0010259 1st arch mesenchyme from neural crest http://purl.obolibrary.org/obo/UBERON_0010359 pharyngeal arch mesenchyme from neural crest Mesenchyme that develops_from a neural crest and is part of a 1st arch mesenchyme. http://purl.obolibrary.org/obo/GO_0140979 intracellular nucleotide homeostasis http://purl.obolibrary.org/obo/GO_0055082 intracellular chemical homeostasis A homeostatic process involved in the maintenance of a steady state level of nucleotides within a cell. http://purl.obolibrary.org/obo/UBERON_0010260 umbilical blood vessel http://purl.obolibrary.org/obo/UBERON_0001981 blood vessel One of the three blood vessels, usually one large umbilical vein and two small umbilical arteries, buried within Wharton's jelly, that transport blood to and from the placenta, where exchange between the mother and fetus takes place; the umbilical vein carries oxygenated, nutrient-rich blood from the placenta to the fetus, and the umbilical arteries carry deoxygenated, nutrient-depleted blood from the fetus to the placenta. http://purl.obolibrary.org/obo/CL_4033040 lung resident memory CD8-positive, CD103-positive, alpha-beta T cell http://purl.obolibrary.org/obo/CL_4033039 lung resident memory CD8-positive, alpha-beta T cell A lung resident memory CD8-positive, alpha-beta T cell that is CD103-positive. http://purl.obolibrary.org/obo/UBERON_0010272 hyoid apparatus http://purl.obolibrary.org/obo/UBERON_0000075 subdivision of skeletal system A group of bones comprised of hyoid body and two pairs of cornua (i.e. greater cornua and lesser cornua), and lies just below the tongue, above the thyroid cartilage. http://purl.obolibrary.org/obo/CL_4033041 CCL3-positive alveolar macrophage http://purl.obolibrary.org/obo/CL_0000583 alveolar macrophage An alveolar macrophage that expresses CCL3. http://purl.obolibrary.org/obo/UBERON_0010273 zone of hyoid bone http://purl.obolibrary.org/obo/UBERON_0005913 zone of bone organ A zone of bone organ that is part of a hyoid bone. http://purl.obolibrary.org/obo/CL_4033042 metallothionein-positive alveolar macrophage http://purl.obolibrary.org/obo/CL_0000583 alveolar macrophage An alveolar macrophage that expresses metallothionein. http://purl.obolibrary.org/obo/UBERON_0010276 space in vertebral column http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space Any anatomical space that is part of a vertebral column. http://purl.obolibrary.org/obo/CL_4033043 lung interstitial macrophage http://purl.obolibrary.org/obo/CL_1001603 lung macrophage A macrophage that is part of the lung connective tissue (pulmonary interstitium). This cell performs tissue remodeling and contributes to barrier immunity through antigen presentation. http://purl.obolibrary.org/obo/UBERON_0010284 lacrimal punctum http://purl.obolibrary.org/obo/UBERON_0000161 orifice A minute orifice on the summit of the papillae lacrimales, which is the commencement point of the lacrimal canaliculi. http://purl.obolibrary.org/obo/CL_4033044 deuterosomal cell http://purl.obolibrary.org/obo/CL_0002368 respiratory tract epithelial cell An epithelial cell part of respiratory tract epithelium that is a precursor of a multi-ciliated cell. This cell actively amplifies centrioles, a required step for multiciliogenesis. http://purl.obolibrary.org/obo/UBERON_0010285 midbrain basal plate http://purl.obolibrary.org/obo/UBERON_0002020 gray matter Portion of tissue that is dorsolateral to the floor plate and part of the midbrain. http://purl.obolibrary.org/obo/CL_4033045 lung migratory dendritic cell http://purl.obolibrary.org/obo/CL_0000451 dendritic cell A dendritic cell that captures antigens in a lung and migrates to a lymph node or to the spleen to activate T cells. http://purl.obolibrary.org/obo/UBERON_0010286 midbrain neural tube http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue Portion of neural tube that gives rise to the midbrain. http://purl.obolibrary.org/obo/CL_4033048 respiratory tract suprabasal cell http://purl.obolibrary.org/obo/CL_7770004 suprabasal cell A respiratory epithelial cell derived from a basal cell, with a topographic nuclear position between the basal and luminal cells of the airway epithelium. This non-basal, intermediate progenitor cell has limited proliferative capacity and can differentiate into multiciliated, secretory, or rare airway cells (ionocytes, tuft cells, neuroendocrine cells). It shares some ultrastructural features with basal cells but lacks the defined characteristics of fully differentiated cellular phenotypes. http://purl.obolibrary.org/obo/UBERON_0010294 scleral endothelium http://purl.obolibrary.org/obo/UBERON_0015808 eye epithelium An endothelium that is part of a sclera. http://purl.obolibrary.org/obo/CL_4030058 TCR-positive macrophage http://purl.obolibrary.org/obo/CL_0000235 macrophage A macrophage that expresses the T cell receptor complex at the cell surface. http://purl.obolibrary.org/obo/UBERON_0010295 substantia propria of sclera http://purl.obolibrary.org/obo/UBERON_0010291 layer of sclera A stroma that is part of a sclera. http://purl.obolibrary.org/obo/CL_4030059 L2/3 intratelencephalic projecting glutamatergic neuron http://purl.obolibrary.org/obo/CL_4023040 L2/3-6 intratelencephalic projecting glutamatergic neuron A transcriptomically distinct intratelencephalic-projecting glutamatergic neuron with a soma found between cortical layer 2-4. This intratelencephalic-projecting glutamatergic neuron has thin-tufted apical dendrites and extends its axonal projection into L5 in the neocortex. This neuronal type has a hyperpolarised resting membrane potential. http://purl.obolibrary.org/obo/UBERON_0010299 scleral mesenchyme http://purl.obolibrary.org/obo/UBERON_0003104 mesenchyme Mesenchyme surrounding the developing optic cup which develops into the sclera. http://purl.obolibrary.org/obo/CL_4030060 L2 intratelencephalic projecting glutamatergic neuron http://purl.obolibrary.org/obo/CL_4023040 L2/3-6 intratelencephalic projecting glutamatergic neuron An intratelencephalic-projecting glutamatergic neuron with a soma found in cortical layer 2. http://purl.obolibrary.org/obo/UBERON_0010302 amnioserosa http://purl.obolibrary.org/obo/UBERON_0010303 extraembryonic epithelium A single extraembryonic epithelium, which closes the germband dorsally. http://purl.obolibrary.org/obo/CL_4030061 L3 intratelencephalic projecting glutamatergic neuron http://purl.obolibrary.org/obo/CL_4023040 L2/3-6 intratelencephalic projecting glutamatergic neuron An intratelencephalic-projecting glutamatergic neuron with a soma found in cortical layer 3. http://purl.obolibrary.org/obo/UBERON_0010303 extraembryonic epithelium http://purl.obolibrary.org/obo/UBERON_0005292 extraembryonic tissue An epithelium that is part of a extraembryonic structure. http://purl.obolibrary.org/obo/CL_4030062 L4/5 intratelencephalic projecting glutamatergic neuron http://purl.obolibrary.org/obo/CL_4023040 L2/3-6 intratelencephalic projecting glutamatergic neuron An intratelencephalic-projecting glutamatergic with a soma located in cortical layer 4/5. http://purl.obolibrary.org/obo/UBERON_0010304 non-keratinized stratified squamous epithelium http://purl.obolibrary.org/obo/UBERON_0006915 stratified squamous epithelium Stratified squamous epithelium is a stratified squamous epithelium, the cells of which synthesizes but does not accumulate keratin. Examples: epithelium of vagina, epithelium of wall of esophagus. http://purl.obolibrary.org/obo/CL_4030063 L4 intratelencephalic projecting glutamatergic neuron http://purl.obolibrary.org/obo/CL_4023040 L2/3-6 intratelencephalic projecting glutamatergic neuron A transcriptomically distinct intratelencephalic-projecting glutamatergic neuron with a soma found in cortical layer 3-4. This neuron type can have a pyramidal, star-pyramidal or spiny stellate morphology and projects its output to L2/3 and L5A/B. http://purl.obolibrary.org/obo/UBERON_0010305 subdivision of conjunctiva http://purl.obolibrary.org/obo/UBERON_0000064 organ part One of the three major regions of the conjunctiva. http://purl.obolibrary.org/obo/CL_4030064 L5 intratelencephalic projecting glutamatergic neuron http://purl.obolibrary.org/obo/CL_4023040 L2/3-6 intratelencephalic projecting glutamatergic neuron An intratelencephalic-projecting glutamatergic neuron with a soma found in cortical layer 5. http://purl.obolibrary.org/obo/UBERON_0010312 immature eye http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure Developing anatomical structure that develops into the eyeball and associated structures. http://purl.obolibrary.org/obo/CL_4030065 L6 intratelencephalic projecting glutamatergic neuron http://purl.obolibrary.org/obo/CL_4023040 L2/3-6 intratelencephalic projecting glutamatergic neuron A transcriptomically distinct intratelencephalic-projecting glutamatergic neuron with a soma found in L6 of the primary motor cortex. These cells are short untufted pyramidal cells, which could be stellate or inverted. http://purl.obolibrary.org/obo/UBERON_0010313 neural crest-derived structure http://purl.obolibrary.org/obo/UBERON_0010314 structure with developmental contribution from neural crest An anatomical structure that develops from the neural crest. http://purl.obolibrary.org/obo/CL_4030066 ureteric bud cell http://purl.obolibrary.org/obo/CL_0002518 kidney epithelial cell An epithelial cell that is part of a ureteric bud. A ureteric bud cell has the potential to induce metanephric mesenchymal cells to proliferate and convert to epithelia that form renal tubules via: (1) the secretion of multiple diffusible growth factors that rescue renal progenitors from apoptosis and stimulate them to proliferate and (2) contact-dependent mechanisms that induce mesenchymal-epithelial conversion. http://purl.obolibrary.org/obo/UBERON_0010314 structure with developmental contribution from neural crest http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure An anatomical structure that has some part that develops from the neural crest. http://purl.obolibrary.org/obo/CL_4033056 onychocyte http://purl.obolibrary.org/obo/CL_4052061 epidermal keratinocyte A terminally differentiated, specialized keratinocyte originating primarily from the nail matrix. During onychokeratinization, these cells undergo progressive flattening and produce high levels of hard, disulfide cross-linked keratins (Eckhart et al., 2024) that form the rigid, compact nail plate. Unlike epidermal keratinocytes, onychocytes are firmly integrated into the nail plate and do not desquamate. http://purl.obolibrary.org/obo/UBERON_0010321 skeletal element of eye region http://purl.obolibrary.org/obo/UBERON_0010313 neural crest-derived structure A skeletal element that is part of a orbital region. http://purl.obolibrary.org/obo/CL_4033057 luminal adaptive secretory precursor cell of mammary gland http://purl.obolibrary.org/obo/CL_0011026 progenitor cell A luminal epithelial cell of the mammary gland that can proliferate and has the potential to differentiate into a lactocyte during pregnancy. In humans, a luminal adaptive secretory precursor cell can be identified by high levels of the markers EpCAM and CD49f, and in mice it can be identified by low levels of CD29 and high levels of CD14, Kit, CD61, and Tspan8. http://purl.obolibrary.org/obo/UBERON_0010323 cranial skeletal system http://purl.obolibrary.org/obo/UBERON_0000075 subdivision of skeletal system Skeletal subdivision of the head including skull (cranium plus mandible), pharyngeal and/or hyoid apparatus. http://purl.obolibrary.org/obo/CL_4033058 luminal hormone-sensing cell of mammary gland http://purl.obolibrary.org/obo/CL_0002326 luminal epithelial cell of mammary gland A luminal epithelial cell of the mammary gland that transduces endocrine cues to orchestrate proliferation, architectural remodeling, and differentiation of other cells in the mammary gland via paracrine signaling. This cell expresses high levels of estrogen receptors. In humans, a luminal hormone-sensing cell can be identified by high levels of EpCAM and low levels of CD49f, and in mice it can be identified by low levels of CD29 and high levels of Foxa1, CD133, and Sca1 (Ly6a). http://purl.obolibrary.org/obo/UBERON_0010328 limb bud mesenchyme http://purl.obolibrary.org/obo/UBERON_0010329 paired limb/fin bud mesenchyme Mesenchyme that is part of a limb bud. http://purl.obolibrary.org/obo/CL_4033059 lactocyte type 1 http://purl.obolibrary.org/obo/CL_0002325 lactocyte A lactocyte that highly expresses genes associated with transcription, immune cell function, and cellular stress. A lactocyte type 1 also expresses genes involved in milk component biosynthesis (e.g., LALBA and CSNs), albeit at lower levels than a lactocyte type 2. http://purl.obolibrary.org/obo/UBERON_0010329 paired limb/fin bud mesenchyme http://purl.obolibrary.org/obo/UBERON_0010377 mesenchyme from somatopleure Mesenchyme that is part of a limb/fin bud. http://purl.obolibrary.org/obo/CL_4033060 lactocyte type 2 http://purl.obolibrary.org/obo/CL_0002325 lactocyte A lactocyte that highly expresses genes associated with lipid production and milk component biosynthesis. http://purl.obolibrary.org/obo/UBERON_0010330 eyelid mesenchyme http://purl.obolibrary.org/obo/UBERON_0003314 eye mesenchyme Mesenchyme that is part of a developing eyelid. http://purl.obolibrary.org/obo/UBERON_8600024 pulmonary venule http://purl.obolibrary.org/obo/UBERON_0003512 lung blood vessel A venule that is part of a lung and drains oxygenated blood from pulmonary capillaries. A pulmonary venule merges into a pulmonary vein branch that runs in the pulmonary interlobular septa. http://purl.obolibrary.org/obo/UBERON_0010332 epithelium of handplate http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue An epithelium that is part of a handplate. http://purl.obolibrary.org/obo/GO_0160165 CD8-positive, alpha-beta T cell homeostasis http://purl.obolibrary.org/obo/GO_0043029 T cell homeostasis The process of regulating the proliferation and elimination of CD8-positive alpha-beta T cells such that the total number of CD8-positive alpha-beta T cells within a whole or part of an organism is stable over time in the absence of an outside stimulus. http://purl.obolibrary.org/obo/UBERON_0010333 extraembryonic membrane mesenchyme http://purl.obolibrary.org/obo/UBERON_0005292 extraembryonic tissue Mesenchyme that is part of a extraembryonic membrane. http://purl.obolibrary.org/obo/UBERON_8450003 embryonic craniocervical region http://purl.obolibrary.org/obo/UBERON_0007811 craniocervical region A craniocervical region that is part of an embryo. http://purl.obolibrary.org/obo/UBERON_0010334 maxillary process mesenchyme from neural crest http://purl.obolibrary.org/obo/UBERON_0010258 mesenchyme from rhombencephalic neural crest Mesenchyme that develops_from a neural crest and is part of a maxillary process mesenchyme. http://purl.obolibrary.org/obo/GO_0140139 solid phase of basement membrane http://purl.obolibrary.org/obo/GO_0030312 external encapsulating structure The solid compartment of the basement membrane ECM, including a specific subset of basement membrane collagens and basement membrane glycoproteins like laminins or nidogens. http://purl.obolibrary.org/obo/UBERON_0010335 maxillary process mesenchyme from head mesenchyme http://purl.obolibrary.org/obo/UBERON_0009526 maxillary process mesenchyme Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a maxillary process mesenchyme. http://purl.obolibrary.org/obo/UBERON_0010336 mandibular process mesenchyme from neural crest http://purl.obolibrary.org/obo/UBERON_0010258 mesenchyme from rhombencephalic neural crest Mesenchyme that develops_from a neural crest and is part of a mandibular process mesenchyme. http://purl.obolibrary.org/obo/UBERON_0010337 mandibular process mesenchyme from head mesenchyme http://purl.obolibrary.org/obo/UBERON_0006905 mandibular process mesenchyme Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a mandibular process mesenchyme. http://purl.obolibrary.org/obo/UBERON_0010338 1st arch maxillary mesenchyme from head mesenchyme http://purl.obolibrary.org/obo/UBERON_0010341 1st arch mesenchyme from head mesenchyme Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a 1st arch maxillary mesenchyme. http://purl.obolibrary.org/obo/UBERON_0010339 1st arch mandibular mesenchyme from head mesenchyme http://purl.obolibrary.org/obo/UBERON_0010341 1st arch mesenchyme from head mesenchyme Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a 1st arch mandibular mesenchyme. http://purl.obolibrary.org/obo/UBERON_0010341 1st arch mesenchyme from head mesenchyme http://purl.obolibrary.org/obo/UBERON_0010360 pharyngeal arch mesenchyme from head mesenchyme Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a 1st arch mesenchyme. http://purl.obolibrary.org/obo/UBERON_0010343 2nd arch mesenchyme from head mesenchyme http://purl.obolibrary.org/obo/UBERON_0010360 pharyngeal arch mesenchyme from head mesenchyme Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a 2nd arch mesenchyme. http://purl.obolibrary.org/obo/UBERON_0010344 3rd arch mesenchyme from head mesenchyme http://purl.obolibrary.org/obo/UBERON_0010360 pharyngeal arch mesenchyme from head mesenchyme Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a 3rd arch mesenchyme. http://purl.obolibrary.org/obo/GO_0140143 collagenous component of basement membrane http://purl.obolibrary.org/obo/GO_0030312 external encapsulating structure Collagenous component of basement membrane ECMs, including collagen IV and other types of collagen specifically expressed in basement membrane. http://purl.obolibrary.org/obo/UBERON_0010345 4th arch mesenchyme from head mesenchyme http://purl.obolibrary.org/obo/UBERON_0010360 pharyngeal arch mesenchyme from head mesenchyme Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a 4th arch mesenchyme. http://purl.obolibrary.org/obo/UBERON_0010347 6th arch mesenchyme from head mesenchyme http://purl.obolibrary.org/obo/UBERON_0010360 pharyngeal arch mesenchyme from head mesenchyme Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a 6th arch mesenchyme. http://purl.obolibrary.org/obo/GO_0140149 non-collagenous component of interstitial matrix http://purl.obolibrary.org/obo/GO_0030312 external encapsulating structure The non-collagenous component of interstitial extracellular matrices, including glycoprotein like fibronectin and elastin. http://purl.obolibrary.org/obo/UBERON_0010349 otic capsule pre-cartilage condensation http://purl.obolibrary.org/obo/UBERON_0004637 otic capsule An otic capsule endochondral element that is composed primarily of a pre-cartilage condensation. http://purl.obolibrary.org/obo/GO_0140151 solid phase of interstitial matrix http://purl.obolibrary.org/obo/GO_0030312 external encapsulating structure The solid compartment of the interstitial matrix, including interstitial collagens such as fibrillar and fibril-associated collagens and non-collagenous glycoproteins like fibronectin and elastin. http://purl.obolibrary.org/obo/UBERON_0010355 ossification center http://purl.obolibrary.org/obo/UBERON_0005913 zone of bone organ The first step in ossification of the cartilage is that the cartilage cells, at the point where ossification is commencing and which is termed a ossification center, enlarge and arrange themselves in rows. The matrix in which they are imbedded increases in quantity, so that the cells become further separated from each other. A deposit of calcareous material now takes place in this matrix, between the rows of cells, so that they become separated from each other by longitudinal columns of calcified matrix, presenting a granular and opaque appearance. Here and there the matrix between two cells of the same row also becomes calcified, and transverse bars of calcified substance stretch across from one calcareous column to another. Thus there are longitudinal groups of the cartilage cells enclosed in oblong cavities, the walls of which are formed of calcified matrix which cuts off all nutrition from the cells; the cells, in consequence, atrophy, leaving spaces called the primary areolC&. http://purl.obolibrary.org/obo/GO_0140152 collagenous component of interstitial matrix http://purl.obolibrary.org/obo/GO_0030312 external encapsulating structure Main components of the interstitial matrix solid phase, including fibrillar and fibril-associated collagens. http://purl.obolibrary.org/obo/GO_0140154 chicken-wire-like collagen network http://purl.obolibrary.org/obo/GO_0098645 complex of network-forming collagens Network-forming collagens can either form a chicken-wire-like network or a hexagonal network. Collagen type IV forms a chicken-wire-like structure and is found in the basement membrane. http://purl.obolibrary.org/obo/UBERON_0010358 arch of centrum of vertebra http://purl.obolibrary.org/obo/UBERON_0004765 skeletal element An arch-shaped structure of the vertebra that extends dorsally (neural arch) or ventrally (hemal arch) from the vertebral centrum. http://purl.obolibrary.org/obo/CL_4301579 CBX MLI Megf11 Gaba_1 molecular layer interneuron (Mmus) http://purl.obolibrary.org/obo/CL_4300351 CBX MLI Megf11 Gaba molecular layer interneuron (Mmus) A molecular layer interneuron of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Dnah11 (Mmus), Sla (Mmus), Gldc (Mmus), Sdk2 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1149 CBX MLI Megf11 Gaba_1. http://purl.obolibrary.org/obo/UBERON_6000002 arthropod tagma http://purl.obolibrary.org/obo/UBERON_0011676 subdivision of organism along main body axis One of the main divisions of the whole organism of arthropods formed from groups of segments. http://purl.obolibrary.org/obo/UBERON_6000137 embryonic tagma http://purl.obolibrary.org/obo/UBERON_6000002 arthropod tagma Any tagma (UBERON:6000002) that is part of some embryo (UBERON:6000052). http://purl.obolibrary.org/obo/UBERON_0010359 pharyngeal arch mesenchyme from neural crest http://purl.obolibrary.org/obo/UBERON_0014387 mesenchyme derived from neural crest Mesenchyme that develops_from a neural crest and is part of a entire pharyngeal arch associated mesenchyme. http://purl.obolibrary.org/obo/UBERON_6001728 insect larval tagma http://purl.obolibrary.org/obo/UBERON_6000002 arthropod tagma Any tagma (UBERON:6000002) that is part of some larva (UBERON:6001727). http://purl.obolibrary.org/obo/UBERON_6001730 insect larval head http://purl.obolibrary.org/obo/UBERON_0000033 head Any head that is part of some larva. http://purl.obolibrary.org/obo/UBERON_0010360 pharyngeal arch mesenchyme from head mesenchyme http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a entire pharyngeal arch associated mesenchyme. http://purl.obolibrary.org/obo/UBERON_6002639 insect larval sense organ http://purl.obolibrary.org/obo/UBERON_0000020 sense organ Any sense organ that is part of some larva. http://purl.obolibrary.org/obo/UBERON_6003005 insect adult tagma http://purl.obolibrary.org/obo/UBERON_6000002 arthropod tagma Any tagma (UBERON:6000002) that is part of some adult (UBERON:6003004). http://purl.obolibrary.org/obo/UBERON_0010362 endoskeleton http://purl.obolibrary.org/obo/UBERON_0010912 subdivision of skeleton Skeletal subdivision that undergoes indirect development and includes elements that develop as a replacement or substitution of other elements or tissues. http://purl.obolibrary.org/obo/UBERON_6003007 insect adult head http://purl.obolibrary.org/obo/UBERON_6003005 insect adult tagma Head of the adult organism. http://purl.obolibrary.org/obo/UBERON_0010363 endochondral element http://purl.obolibrary.org/obo/UBERON_0004765 skeletal element A skeletal element that has the potential to participate in endochondral ossification, and may participate in intramembranous ossification. http://purl.obolibrary.org/obo/UBERON_6007240 insect embryonic/larval sensillum http://purl.obolibrary.org/obo/UBERON_6002639 insect larval sense organ Any sensillum (UBERON:6007152) that is part of some larva (UBERON:6001727). http://purl.obolibrary.org/obo/UBERON_0010364 dermal skeleton http://purl.obolibrary.org/obo/UBERON_0010912 subdivision of skeleton Skeletal subdivision that undergoes direct development and includes elements that either develop in association with the basement membrane of the ectoderm or are homologous with such elements; includes dermatocranium, components of the appendicular skeleton, teeth and tooth-like elements of the oropharynx, and integumentary elements. http://purl.obolibrary.org/obo/UBERON_6007242 insect embryonic/larval head sensillum http://purl.obolibrary.org/obo/UBERON_6007280 insect embryonic/larval head sense organ Any sensillum (UBERON:6007152) that is part of some larval head (UBERON:6001730). http://purl.obolibrary.org/obo/UBERON_6007280 insect embryonic/larval head sense organ http://purl.obolibrary.org/obo/UBERON_6002639 insect larval sense organ Any sense organ (UBERON:6005155) that is part of some larval head (UBERON:6001730). http://purl.obolibrary.org/obo/UBERON_0010365 odontoid tissue http://purl.obolibrary.org/obo/UBERON_0004755 skeletal tissue Skeletal tissue that is part of the exoskeleton and derived from an odontogenic papilla. http://purl.obolibrary.org/obo/GO_0061900 glial cell activation http://purl.obolibrary.org/obo/GO_0001775 cell activation A change in morphology and behavior of a glial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. http://purl.obolibrary.org/obo/UBERON_0010366 conjunctival vasculature http://purl.obolibrary.org/obo/UBERON_0002203 vasculature of eye A vasculature that is part of a conjunctiva. http://purl.obolibrary.org/obo/UBERON_0036217 coelomic fluid http://purl.obolibrary.org/obo/UBERON_0006314 bodily fluid A bodily fluid that is located in the coelom. http://purl.obolibrary.org/obo/UBERON_0010367 conjunctival vein http://purl.obolibrary.org/obo/UBERON_0009141 craniocervical region vein A vein that is part of a conjunctiva. http://purl.obolibrary.org/obo/UBERON_0036242 post-embryonic notochord http://purl.obolibrary.org/obo/UBERON_0002328 notochord A notochord that has persisted beyond the embryonic stage. http://purl.obolibrary.org/obo/UBERON_0010368 pulmonary lobule http://purl.obolibrary.org/obo/UBERON_0009911 lobule The smallest anatomical unit of the lung, measuring 0.50 to 2.00 cm in diameter. Each lobule is composed of 4-8 terminal bronchioles and their distal alveolar ducts and sacs. The lobules are separated by fibrous interlobular septa. http://purl.obolibrary.org/obo/UBERON_0036243 vaginal fluid http://purl.obolibrary.org/obo/UBERON_0006314 bodily fluid Fluid that lines the vaginal walls that consists of multiple secretions that collect in the vagina from different glands. http://purl.obolibrary.org/obo/UBERON_0010369 secondary pulmonary lobule http://purl.obolibrary.org/obo/UBERON_0010368 pulmonary lobule A unit of lung supplied by three to five terminal bronchioles and contained by fibrous septa. http://purl.obolibrary.org/obo/UBERON_0036262 uterine ligament http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure Any of the eight ligaments pertaining to the uterus including the anterior, posterior, lateral, sacro-uterine and round ligaments. http://purl.obolibrary.org/obo/UBERON_0010370 tibial vein http://purl.obolibrary.org/obo/UBERON_0003503 leg blood vessel One of the veins of the lower leg; empty into the popliteal vein. http://purl.obolibrary.org/obo/PATO_0045086 normal occurrence http://purl.obolibrary.org/obo/PATO_0045073 normal process quality An occurrence which is relatively normal. http://purl.obolibrary.org/obo/UBERON_0010371 ecto-epithelium http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure Epithelium composed of cells that develops from the ectoderm[FMA,modified]. http://purl.obolibrary.org/obo/GO_0140244 regulation of translation at presynapse http://purl.obolibrary.org/obo/GO_0140243 regulation of translation at synapse Any process that regulates translation occurring at the presynapse. http://purl.obolibrary.org/obo/UBERON_0010377 mesenchyme from somatopleure http://purl.obolibrary.org/obo/UBERON_0007524 dense mesenchyme tissue Mesenchyme that develops_from a somatopleure. http://purl.obolibrary.org/obo/GO_0106214 regulation of vesicle fusion with Golgi apparatus http://purl.obolibrary.org/obo/GO_1903358 regulation of Golgi organization Any process that modulates the frequency, rate or extent of vesicle fusion with Golgi apparatus. http://purl.obolibrary.org/obo/UBERON_0010378 mesenchyme from splanchnopleure http://purl.obolibrary.org/obo/UBERON_0007524 dense mesenchyme tissue Mesenchyme that develops_from a splanchnopleure. http://purl.obolibrary.org/obo/GO_0106215 negative regulation of vesicle fusion with Golgi apparatus http://purl.obolibrary.org/obo/GO_0106214 regulation of vesicle fusion with Golgi apparatus Any process that stops, prevents or reduces the frequency, rate or extent of vesicle fustion with Golgi apparatus. http://purl.obolibrary.org/obo/UBERON_0010380 enteric nerve http://purl.obolibrary.org/obo/UBERON_0001021 nerve The neurons that innervate the esophagus, stomach, small and large bowel. http://purl.obolibrary.org/obo/GO_0106216 positive regulation of vesicle fusion with Golgi apparatus http://purl.obolibrary.org/obo/GO_0106214 regulation of vesicle fusion with Golgi apparatus Any process that activates or increases the frequency, rate or extent of vesicle fusion with Golgi apparatus. http://purl.obolibrary.org/obo/UBERON_0010386 Peyer's patch follicle http://purl.obolibrary.org/obo/UBERON_0000444 lymphoid follicle A lymphoid follicle that is part of a Peyer's patch. http://purl.obolibrary.org/obo/UBERON_0010387 Peyer's patch T cell area http://purl.obolibrary.org/obo/UBERON_0013765 digestive system element The Peyer's patch area normally occupied by T lymphocytes. http://purl.obolibrary.org/obo/GO_0120213 regulation of histidine biosynthetic process http://purl.obolibrary.org/obo/GO_2000282 regulation of amino acid biosynthetic process Any process that modulates the frequency, rate or extent of histidine biosynthetic process. http://purl.obolibrary.org/obo/UBERON_0010388 proximal segment of rib http://purl.obolibrary.org/obo/UBERON_0005913 zone of bone organ The segment of the rib that connects to a vertebra[MP]. a small part of the rib composed of the head, neck, tuberculum and a short proximal part of the body[PMID]. http://purl.obolibrary.org/obo/GO_0120214 negative regulation of histidine biosynthetic process http://purl.obolibrary.org/obo/GO_0120213 regulation of histidine biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of histidine biosynthetic process. http://purl.obolibrary.org/obo/UBERON_0010390 lumen of urethra http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space An organ cavity that is part of a urethra. http://purl.obolibrary.org/obo/GO_0120215 positive regulation of histidine biosynthetic process http://purl.obolibrary.org/obo/GO_0120213 regulation of histidine biosynthetic process Any process that activates or increases the frequency, rate or extent of histidine biosynthetic process. http://purl.obolibrary.org/obo/UBERON_0010395 lymph node primary follicle http://purl.obolibrary.org/obo/UBERON_0010748 lymph node follicle An unstimulated network of follicular dendritic cells and small resting B cells in the lymph node cortex. http://purl.obolibrary.org/obo/GO_0150106 regulation of protein localization to cell-cell junction http://purl.obolibrary.org/obo/GO_0032880 regulation of protein localization Any process that modulates the frequency, rate or extent of protein localization to cell-cell junction. http://purl.obolibrary.org/obo/UBERON_0010397 efferent lymphatic vessel http://purl.obolibrary.org/obo/UBERON_0001473 lymphatic vessel Lymphatic vessel that exits the lymph node. The efferent lymphatic vessel commences from the lymph sinuses of the medullary portion of the lymph nodes and leave the lymph nodes either to veins or greater nodes. Efferent lymphatic vessels are also found in the thymus and spleen. This is in contrast to afferent lymphatic vessels, which are found only in lymph nodes. http://purl.obolibrary.org/obo/GO_0150107 positive regulation of protein localization to cell-cell junction http://purl.obolibrary.org/obo/GO_0150106 regulation of protein localization to cell-cell junction Any process that activates or increases the frequency, rate or extent of protein localization to cell-cell junction. http://purl.obolibrary.org/obo/CL_4023058 mesothelial fibroblast of the leptomeninx http://purl.obolibrary.org/obo/CL_4023054 mesothelial fibroblast A mesothelial fibroblast found in the leptomeninx. http://purl.obolibrary.org/obo/UBERON_0010399 spleen trabecular artery http://purl.obolibrary.org/obo/UBERON_0003497 abdomen blood vessel One of the branches of the splenic artery[MP]. http://purl.obolibrary.org/obo/UBERON_0010400 spleen trabecular vein http://purl.obolibrary.org/obo/UBERON_0013126 vein of abdomen One of the veins that feed the splenic vein. http://purl.obolibrary.org/obo/CL_0008048 upper motor neuron http://purl.obolibrary.org/obo/CL_0000679 glutamatergic neuron A glutamatergic motor neuron with a soma in the brainstem or cerebral cortex. They do not synapse directly to muscles but rather to lower motor neurons, which do. They are the main controllers of voluntary movement. http://purl.obolibrary.org/obo/UBERON_0010402 epidermis suprabasal layer http://purl.obolibrary.org/obo/UBERON_0013754 integumentary system layer Any layer of the epidermis that is superior to the stratum basale. http://purl.obolibrary.org/obo/CL_4023053 spinal interneuron synapsing Betz cell http://purl.obolibrary.org/obo/CL_0008049 Betz cell A Betz cell that syanpses with spinal interneurons. http://purl.obolibrary.org/obo/UBERON_0010403 brain marginal zone http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure The part of the future brain that is derived from the mantle layer of the neural tube. http://purl.obolibrary.org/obo/CL_0009031 T cell of appendix http://purl.obolibrary.org/obo/CL_0000084 T cell A T cell that is located in a vermiform appendix. http://purl.obolibrary.org/obo/UBERON_0010409 ocular surface region http://purl.obolibrary.org/obo/UBERON_0000063 organ subunit The integrated unit (of the eye) that consists of the conjunctiva, the corneal surface, and the ocular mucosal adnexa including the lid margins and the meibomian gland openings, the lacrimal glands and the lacrimal drainage system, all which are critical to maintain ocular surface integrity and provide protection from external antigens and pathogenic microorganisms. http://purl.obolibrary.org/obo/GO_0140669 negative regulation of oxytocin production http://purl.obolibrary.org/obo/GO_0140667 regulation of oxytocin production Any process that stops, prevents, or reduces the rate of production of oxytocin. http://purl.obolibrary.org/obo/CL_0011030 dermal microvascular endothelial cell http://purl.obolibrary.org/obo/CL_2000010 dermis blood vessel endothelial cell Any microvascular endothelial cell that is part of the dermis. http://purl.obolibrary.org/obo/UBERON_0010416 lymph node B cell domain http://purl.obolibrary.org/obo/UBERON_0010392 B cell domain A part of the lymph node cortex in which B lymphocytes home to primary follicles to survey follicular dendritic cells (FDCs); antigen stimulated B cells proliferate and differentiate within the follicles forming distinctive germinal centers. http://purl.obolibrary.org/obo/PR_000050522 medium-wave-sensitive opsin (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A medium-wave-sensitive opsin that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0010417 lymph node T cell domain http://purl.obolibrary.org/obo/UBERON_0010393 T cell domain The paracortex and interfollicular cortex of the lymph node in which T lymphocytes home to survey dendritic cells. http://purl.obolibrary.org/obo/CL_4023128 rostral periventricular region of the third ventricle KNDy neuron http://purl.obolibrary.org/obo/CL_4023125 KNDy neuron a KNDy neuron that is located in the rostral periventricular region of the third ventricle. http://purl.obolibrary.org/obo/UBERON_0010418 urethral opening http://purl.obolibrary.org/obo/UBERON_0000161 orifice An orifice that is part of a lower urinary tract. http://purl.obolibrary.org/obo/CL_4023122 oxytocin receptor sst GABAergic cortical interneuron http://purl.obolibrary.org/obo/CL_0010011 cerebral cortex GABAergic interneuron An interneuron located in the cerebral cortex that expresses the oxytocin receptor. These interneurons also express somatostatin. http://purl.obolibrary.org/obo/UBERON_0010420 lymph node germinal center mantle zone http://purl.obolibrary.org/obo/UBERON_0010755 secondary follicle corona A part of the secondary follicle in which naive B cells reside along with some helper T cells, macrophages and follicular dendritic cells; these are displaced by the expanding germinal centre and form a 'mantle' around it. http://purl.obolibrary.org/obo/CL_0009114 monocytoid B cell http://purl.obolibrary.org/obo/CL_0000236 B cell A B cell found in the perisinusoidal area of a lymph node. In humans, monocytoid B cells are a morphologically distinct B cell population (oval nuclei, abundant cytoplasm, monocyte-like appearance), share many similarities with marginal zone B cells including marker expression, and are increased in disease settings. http://purl.obolibrary.org/obo/UBERON_0010421 spleen B cell corona http://purl.obolibrary.org/obo/UBERON_0010755 secondary follicle corona The area of the (spleen) secondary B follicle that surrounds the germinal center and harbors the small recirculating B lymphocytes. http://purl.obolibrary.org/obo/UBERON_0010422 primary nodular lymphoid tissue http://purl.obolibrary.org/obo/UBERON_0000444 lymphoid follicle A lymphoid follicle containing naive B cells. http://purl.obolibrary.org/obo/CL_4030010 epithelial cell of proximal tubule segment 2 http://purl.obolibrary.org/obo/CL_1000838 kidney proximal convoluted tubule epithelial cell A brush border cell that is part of segment 2 (S2) of the proximal tubule epithelium, located in the renal cortex. In addition to its reabsorptive functions, it is also specialized in the secretion of organic anions and cations, including para-aminohippurate. http://purl.obolibrary.org/obo/UBERON_0010423 primary lymphoid nodule of tonsil http://purl.obolibrary.org/obo/UBERON_0010422 primary nodular lymphoid tissue A primary nodular lymphoid tissue that is part of a tonsil. http://purl.obolibrary.org/obo/PATO_0070061 double bouquet morphology http://purl.obolibrary.org/obo/PATO_0070027 bitufted dendrite cell morphology A cell morphology that inheres in neurons with bitufted dendritic morphology but with the special feature of a tight fascicular axonal cylinder that resembles a 'horse tail'. http://purl.obolibrary.org/obo/UBERON_0010425 internal naris http://purl.obolibrary.org/obo/UBERON_0000003 naris A naris that is located inside the nasal cavity and connects to the pharynx. http://purl.obolibrary.org/obo/UBERON_0010427 ciliary processes http://purl.obolibrary.org/obo/UBERON_0000481 multi-tissue structure The ciliary processes are formed by the inward folding of the various layers of the choroid, i.e. , the choroid proper and the lamina basalis, and are received between corresponding foldings of the suspensory ligament of the lens. http://purl.obolibrary.org/obo/CL_0004243 WF3-2 amacrine cell http://purl.obolibrary.org/obo/CL_0004253 wide field retinal amacrine cell An amacrine cell with a wild dendritic field, dendrites in S3, and post-synaptic terminals in S3. Dendrites have spikes, cross over each other, and cover a larger volume than dendrties of W3-1 retinal amacrine cells. http://purl.obolibrary.org/obo/CL_0004223 AB diffuse-1 amacrine cell http://purl.obolibrary.org/obo/CL_0004251 narrow field retinal amacrine cell A amacrine cell with a small dendritic field and post-synaptic terminals in S1, S2, S3, and S4. AB diffuse-1 amacrine cells have a tent-shaped dendritic arbor and undulate dendrites. http://purl.obolibrary.org/obo/UBERON_0010428 flat bone http://purl.obolibrary.org/obo/UBERON_0001474 bone element A bone that is shaped as a broad flat plate and composed of two thin layers of compact tissue enclosing between them a variable quantity of cancellous tissue, which is the location of red bone marrow. http://purl.obolibrary.org/obo/UBERON_0010498 pseudostratified columnar epithelium http://purl.obolibrary.org/obo/UBERON_0000485 simple columnar epithelium A simple columnar epithelium that looks stratified but is not, because its cells are arranged with their nuclei at different levels. http://purl.obolibrary.org/obo/CL_0020011 hair follicle associated fibroblast http://purl.obolibrary.org/obo/CL_0002620 skin fibroblast A specialized dermal fibroblast within the hair follicle mesenchymal compartment that participates in epithelial-mesenchymal signaling to regulate hair morphogenesis, cycling, and homeostasis through production of inductive signals and extracellular matrix maintenance. http://purl.obolibrary.org/obo/UBERON_0010499 pseudostratified ciliated columnar epithelium http://purl.obolibrary.org/obo/UBERON_0010498 pseudostratified columnar epithelium Epithelium composed of a single layer of cells, appearing as layered because the column-shaped cells vary in height so the nuclei are at different levels. The basal portions of all the cells are in contact with the basement membrane. It lines the respiratory system and the male reproductive tract. The cilia in the respiratory tract are motile, while the stereocilia in the male reproductive tract are immobile. http://purl.obolibrary.org/obo/CL_0020012 hair follicle isthmus-associated fibroblast http://purl.obolibrary.org/obo/CL_0020011 hair follicle associated fibroblast A fibroblast that is part of the hair follicle isthmus (mid-hair shaft). In humans, this cell expresses CRABP1/COCH/RSPO4 and tendon-associated genes (MKX, TNMD). http://purl.obolibrary.org/obo/CL_0020013 dermal sheath fibroblast http://purl.obolibrary.org/obo/CL_0020011 hair follicle associated fibroblast A fibroblast forming the connective tissue sheath that encloses the hair follicle epithelium from the level of the bulge downward to the hair bulb. This cell expresses characteristic markers, including DPEP1 in humans and COL11A1 and ACTA2 (alpha-smooth muscle actin) in mice and humans. Dermal sheath fibroblast possesses contractile properties mediated by calcium-calmodulin-myosin light chain kinase signalling, generating centripetal force during hair follicle catagen that relocates the dermal papilla to the stem cell niche. http://purl.obolibrary.org/obo/UBERON_0010521 electroreceptor organ http://purl.obolibrary.org/obo/UBERON_0000020 sense organ An organ that is capable of detecting electrical stimulus. http://purl.obolibrary.org/obo/UBERON_0010522 replacement element http://purl.obolibrary.org/obo/UBERON_0004765 skeletal element Skeletal element that forms as a replacement or substitution of another element or tissue. http://purl.obolibrary.org/obo/UBERON_0010523 microcirculatory vessel http://purl.obolibrary.org/obo/UBERON_0000055 vessel A vessel of the microcirculature, lying between the arterioles and venules; includes capillaries (blood and lymphatic), metarterioles and arteriovenous anastomoses. http://purl.obolibrary.org/obo/CL_0020014 intrinsically photosensitive retinal ganglion cell http://purl.obolibrary.org/obo/CL_0000740 retinal ganglion cell A retinal ganglion cell that is intrinsically photosensitive, functioning as a non-image-forming photoreceptor, distinguished from rod and cone photoreceptors by the expression of the photopigment melanopsin in mice and humans (Hattar et al., 2002; Tri Hoang Do & Yau, 2015). Located primarily in the ganglion cell layer with some displaced somata in the inner nuclear layer, this neuron depolarises directly in response to environmental irradiance (Tri Hoang Do & Yau, 2015). It projects via the retinohypothalamic tract to central targets, including the suprachiasmatic nucleus (SCN) for circadian photoentrainment and the olivary pretectal nucleus (OPN) for the pupillary light reflex. http://purl.obolibrary.org/obo/UBERON_0010527 cavity of bone organ http://purl.obolibrary.org/obo/UBERON_0002558 organ cavity An organ cavity that surrounded_by a bone. http://purl.obolibrary.org/obo/UBERON_0010532 primitive nephron http://purl.obolibrary.org/obo/UBERON_0006555 excretory tube An epithelial tube that is fated to become a nephron. http://purl.obolibrary.org/obo/CL_0020015 transitional principal-intercalated cell of kidney collecting duct http://purl.obolibrary.org/obo/CL_1000454 kidney collecting duct epithelial cell A transitional cell located in the renal collecting duct that co-expresses markers of both principal cell (PC) and intercalated cell (IC). This hybrid cell is enriched in Chronic Kidney Disease (CKD). http://purl.obolibrary.org/obo/UBERON_0010533 metanephros cortex http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure The metanephric cortex is the outer region of the metanephros[GO]. http://purl.obolibrary.org/obo/CL_4072103 hair follicle dermal stem cell http://purl.obolibrary.org/obo/CL_0002559 hair follicle cell A bipotent mesenchymal stem cell that resides in the dermal sheath, specifically within the dermal sheath cup at the base of the hair follicle, characterized by its capacity for self-renewal and differentiation into both dermal sheath and dermal papilla cells throughout hair cycling. In humans, this cell is marked by enriched expression of gremlin-2 (GREM2) and dipeptidase-1 (DPEP1), and acts as a progenitor reservoir sustaining and regenerating the follicle's mesenchymal compartments. http://purl.obolibrary.org/obo/UBERON_0010534 primitive mesonephric nephron http://purl.obolibrary.org/obo/UBERON_0010532 primitive nephron Anatomical cluster which give rise to mature mesonephric nephrons. Zebrafish continously generate new mesonephric nephrons. http://purl.obolibrary.org/obo/CL_4310083 GPin-BF cholinergic-GABAergic neuron (Primate) http://purl.obolibrary.org/obo/CL_0008061 GABA-Chol neuron A GABA-Chol neuron of the Primates brain. These cells are located in the striatum, external segment of globus pallidus . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:GPin-BF Cholinergic GABA. http://purl.obolibrary.org/obo/UBERON_0010535 primitive metanephric nephron http://purl.obolibrary.org/obo/UBERON_0010532 primitive nephron A primitive nephron that is part of a metanephros. http://purl.obolibrary.org/obo/UBERON_0010537 mesonephric nephron progenitor http://purl.obolibrary.org/obo/UBERON_0010536 nephron progenitor Cluster of cells comprising a portion of tissue which gives rise to new mesonephric nephrons. The cluster contains self-renewing stem cells. http://purl.obolibrary.org/obo/CL_4310084 striatal LAMP5 CXCL14 GABAergic interneuron (Primate) http://purl.obolibrary.org/obo/CL_4023011 lamp5 GABAergic interneuron A lamp5 GABAergic interneuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:LAMP5-CXCL14 GABA. http://purl.obolibrary.org/obo/UBERON_0010538 paired limb/fin segment http://purl.obolibrary.org/obo/UBERON_0010758 subdivision of organism along appendicular axis An appendage segment that is part of a limb/fin. http://purl.obolibrary.org/obo/UBERON_0010540 tarsus pre-cartilage condensation http://purl.obolibrary.org/obo/UBERON_0015050 tarsus endochondral element A pre-cartilage condensation that has the potential to develop into a tarsal bone. http://purl.obolibrary.org/obo/CL_4310085 striatal LAMP5 LHX6 GABAergic interneuron (Primate) http://purl.obolibrary.org/obo/CL_4042013 Lamp5 Lhx6 neuron A Lamp5 Lhx6 neuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:LAMP5-LHX6 GABA. http://purl.obolibrary.org/obo/UBERON_0010541 tarsus cartilage element http://purl.obolibrary.org/obo/UBERON_0015050 tarsus endochondral element A cartilaginous condensation that has the potential to develop into a tarsal bone. http://purl.obolibrary.org/obo/UBERON_0010543 acropodial skeleton http://purl.obolibrary.org/obo/UBERON_0010712 limb skeleton subdivision The subdivision of the skeleton that consists of all the skeletal elements at the distalmost end of the autopodium - i.e. the bones of the digits or their cartilaginous precursors[VSAO,modified]. http://purl.obolibrary.org/obo/CL_4310088 BF SKOR1 Glut glutamatergic neuron of the basal ganglia (Primate) http://purl.obolibrary.org/obo/CL_0000700 dopaminergic neuron A glutamatergic neuron of the basal ganglia of the Primates brain. These cells are located in the striatum, external segment of globus pallidus . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:BF SKOR1 Glut. http://purl.obolibrary.org/obo/UBERON_0010544 metacarpus skeleton http://purl.obolibrary.org/obo/UBERON_0015042 manual digit metacarpus endochondral element The metacarpus is the intermediate part of the manus skeleton that is located between the phalanges (bones of the fingers) distally and the carpus which forms the connection to the forearm. The metacarpus consists of metacarpal bones. The metacarpals form a transverse arch to which the rigid row of distal carpal bones are fixed. The peripheral metacarpals (those of the thumb and little finger) form the sides of the cup of the palmar gutter and as they are brought together they deepen this concavity. The index metacarpal is the most firmly fixed, while the thumb metacarpal articulates with the trapezium and acts independently from the others. The middle metacarpals are tightly united to the carpus by intrinsic interlocking bone elements at their bases. The ring metacarpal forms a transitional element of the semi-independent last metacarpal. [WP,unvetted]. http://purl.obolibrary.org/obo/CL_4310093 arkypallidal neuron (Primate) http://purl.obolibrary.org/obo/CL_0020010 arkypallidal neuron A arkypallidal neuron of the Primates brain. These cells are located in the striatum, external segment of globus pallidus . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:GPe MEIS2-SOX6 GABA. http://purl.obolibrary.org/obo/CL_4310094 prototypic neuron (Primate) http://purl.obolibrary.org/obo/CL_0020009 prototypic neuron A prototypic neuron of the Primates brain. These cells are located in the striatum, external segment of globus pallidus . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:GPe SOX6-CTXND1 GABA. http://purl.obolibrary.org/obo/UBERON_0010545 metatarsus skeleton http://purl.obolibrary.org/obo/UBERON_0015036 pedal digit metatarsal endochondral element Limb segment that consists of the long bones of the pes. The metatarsals are analogous to the metacarpal bones of the manus. http://purl.obolibrary.org/obo/CL_4310095 GPi Core neuron (Primate) http://purl.obolibrary.org/obo/CL_0020003 internal globus pallidus core projecting neuron A internal globus pallidus core projecting neuron of the Primates brain. These cells are located in the internal segment of globus pallidus . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:GPi Core. http://purl.obolibrary.org/obo/UBERON_0010546 metapodial skeleton http://purl.obolibrary.org/obo/UBERON_0010712 limb skeleton subdivision Subdivision of skeleton that corresponds to metapodium region, between acropodial skeleton and mesopdoial skeleton. http://purl.obolibrary.org/obo/CL_4310096 GPi Shell neuron (Primate) http://purl.obolibrary.org/obo/CL_0020004 internal globus pallidus shell projection neuron A internal globus pallidus shell projection neuron of the Primates brain. These cells are located in the striatum, external segment of globus pallidus, internal segment of globus pallidus . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:GPi Shell. http://purl.obolibrary.org/obo/UBERON_0010585 pedal digit phalanx pre-cartilage condensation http://purl.obolibrary.org/obo/UBERON_0015030 pedal digit phalanx endochondral element A pre-cartilage condensation that is part of a pedal digit mesenchyme. http://purl.obolibrary.org/obo/UBERON_0010586 manual digit phalanx pre-cartilage condensation http://purl.obolibrary.org/obo/UBERON_0015024 manual digit phalanx endochondral element A pre-cartilage condensation that is part of a manual digit mesenchyme. http://purl.obolibrary.org/obo/CL_4310100 GPe-NDB-SI LHX6-LHX8-GBX1 GABA GABAergic interneuron (Primate) http://purl.obolibrary.org/obo/CL_0011005 GABAergic interneuron A GABAergic interneuron of the Primates brain. These cells are located in the striatum, external segment of globus pallidus . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:GPe-NDB-SI LHX6-LHX8-GBX1 GABA. http://purl.obolibrary.org/obo/UBERON_0010685 pedal digit phalanx cartilage element http://purl.obolibrary.org/obo/UBERON_0035129 pes cartilage element A cartilage element that is part of a pedal digit mesenchyme. http://purl.obolibrary.org/obo/UBERON_0010686 manual digit phalanx cartilage element http://purl.obolibrary.org/obo/UBERON_0035128 manus cartilage element A cartilage element that is part of a manual digit mesenchyme. http://purl.obolibrary.org/obo/CL_4310104 Islands of Calleja granule cell (Primate) http://purl.obolibrary.org/obo/CL_4030053 Islands of Calleja granule cell A Islands of Calleja granule cell of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:OT D1 ICj. http://purl.obolibrary.org/obo/UBERON_0010688 skeleton of manual acropodium http://purl.obolibrary.org/obo/UBERON_0010543 acropodial skeleton The subdivision of the skeleton that consists of all the skeletal elements at the distalmost end of the manual autopodium - i.e. the bones of the hands or their cartilaginous precursors[VSAO,modified]. http://purl.obolibrary.org/obo/CL_4310109 SN-VTR CALB1 Dopa substantia nigra dopaminergic neuron (Primate) http://purl.obolibrary.org/obo/CL_4042025 substantia nigra dopaminergic neuron A substantia nigra dopaminergic neuron of the Primates brain. These cells are located in the substantia nigra . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:SN-VTR CALB1 Dopa. http://purl.obolibrary.org/obo/UBERON_0010695 mesenchyme of tarsal region http://purl.obolibrary.org/obo/UBERON_0003860 hindlimb mesenchyme Mesenchyme of the carpal region that contributes to the tarsal skeleton. http://purl.obolibrary.org/obo/CL_4310110 SN EBF2 GABA GABAergic interneuron (Primate) http://purl.obolibrary.org/obo/CL_0011005 GABAergic interneuron A GABAergic interneuron of the Primates brain. These cells are located in the striatum, substantia nigra . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:SN EBF2 GABA. http://purl.obolibrary.org/obo/UBERON_0010696 skeleton of pedal acropodium http://purl.obolibrary.org/obo/UBERON_0010543 acropodial skeleton The subdivision of the skeleton that consists of all the skeletal elements at the distalmost end of the pedal autopodium - i.e. the bones of the foot or their cartilaginous precursors[cjm]. http://purl.obolibrary.org/obo/UBERON_0010702 digit mesenchyme http://purl.obolibrary.org/obo/UBERON_0009749 limb mesenchyme Mesenchyme of the digit region. http://purl.obolibrary.org/obo/CL_4310111 SN-VTR GAD2 Dopa dopaminergic neuron (Primate) http://purl.obolibrary.org/obo/CL_4042025 substantia nigra dopaminergic neuron A dopaminergic neuron of the Primates brain. These cells are located in the striatum, substantia nigra . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:SN-VTR GAD2 Dopa. http://purl.obolibrary.org/obo/UBERON_0010703 forelimb zeugopod skeleton http://purl.obolibrary.org/obo/UBERON_0011584 zeugopodial skeleton The collection of all skeletal elements in an forelimb zeugopod region. http://purl.obolibrary.org/obo/CL_4310112 SN GATA3-PAX8 GABA GABAergic interneuron (Primate) http://purl.obolibrary.org/obo/CL_0011005 GABAergic interneuron A GABAergic interneuron of the Primates brain. These cells are located in the substantia nigra . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:SN GATA3-PAX8 GABA. http://purl.obolibrary.org/obo/UBERON_0010707 appendage girdle complex http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure An organism subdivision that includes both an appendage and its associated girdle region. Note that this includes both the skeletal elements and associated tissues (integument, muscle, etc). http://purl.obolibrary.org/obo/CL_4310113 SN GATA3-PVALB GABA GABAergic neuron (Primate) http://purl.obolibrary.org/obo/CL_0000617 GABAergic neuron A GABAergic neuron of the Primates brain. These cells are located in the substantia nigra . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:SN GATA3-PVALB GABA. http://purl.obolibrary.org/obo/UBERON_0010708 pectoral complex http://purl.obolibrary.org/obo/UBERON_0010707 appendage girdle complex Appendage girdle complex that when present, encompasses the pectoral appendicular skeleton and the pectoral girdle. http://purl.obolibrary.org/obo/UBERON_0010709 pelvic complex http://purl.obolibrary.org/obo/UBERON_0010707 appendage girdle complex Appendage girdle complex that when present, encompasses the pelvic appendicular skeleton and the pelvic girdle. http://purl.obolibrary.org/obo/CL_4310114 SN SEMA5A GABA GABAergic interneuron (Primate) http://purl.obolibrary.org/obo/CL_0011005 GABAergic interneuron A GABAergic interneuron of the Primates brain. These cells are located in the striatum, subthalamic nucleus, substantia nigra . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:SN SEMA5A GABA. http://purl.obolibrary.org/obo/UBERON_0010712 limb skeleton subdivision http://purl.obolibrary.org/obo/UBERON_0010912 subdivision of skeleton Skeletal subdivision that is a segment of the limb skeleton. http://purl.obolibrary.org/obo/CL_4310115 SN SOX6 Dopa substantia nigra dopaminergic neuron (Primate) http://purl.obolibrary.org/obo/CL_4042025 substantia nigra dopaminergic neuron A substantia nigra dopaminergic neuron of the Primates brain. These cells are located in the substantia nigra . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:SN SOX6 Dopa. http://purl.obolibrary.org/obo/UBERON_0010714 iliac cartilage element http://purl.obolibrary.org/obo/UBERON_0015054 iliac endochondral element An iliac endochondral element that is composed primarily of cartilage tissue. http://purl.obolibrary.org/obo/UBERON_0010719 girdle skeleton http://purl.obolibrary.org/obo/UBERON_0010912 subdivision of skeleton The subdivision of the skeleton of either the pectoral or pelvic girdle. http://purl.obolibrary.org/obo/CL_4310117 SN-VTR-HTH GATA3-TCF7L2 GABA GABAergic interneuron (Primate) http://purl.obolibrary.org/obo/CL_0011005 GABAergic interneuron A GABAergic interneuron of the Primates brain. These cells are located in the substantia nigra . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:SN-VTR-HTH GATA3-TCF7L2 GABA. http://purl.obolibrary.org/obo/UBERON_0010720 hindlimb zeugopod skeleton http://purl.obolibrary.org/obo/UBERON_0011584 zeugopodial skeleton Subdivision of skeleton consisting of all skeletal elements in an hindlimb zeugopod region. Typically consists of the tibia and the fibula. http://purl.obolibrary.org/obo/CL_4310118 STH PVALB-PITX2 Glut glutamatergic neuron of the basal ganglia (Primate) http://purl.obolibrary.org/obo/CL_0000700 dopaminergic neuron A glutamatergic neuron of the basal ganglia of the Primates brain. These cells are located in the subthalamic nucleus . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STH PVALB-PITX2 Glut. http://purl.obolibrary.org/obo/UBERON_0010728 sphenoid lesser wing pre-cartilage condensation http://purl.obolibrary.org/obo/UBERON_0015059 orbitosphenoid endochondral element An orbitosphenoid endochondral element that is composed primarily of a pre-cartilage condensation. http://purl.obolibrary.org/obo/UBERON_0010740 bone of appendage girdle complex http://purl.obolibrary.org/obo/UBERON_0001474 bone element A bone that is part of an appendage girdle complex (i.e. any bone in a limb, fin or girdle). http://purl.obolibrary.org/obo/CL_4310120 striatal pthlh-expressing interneuron (Primate) http://purl.obolibrary.org/obo/CL_4042023 striatal pthlh-expressing interneuron A striatal pthlh-expressing interneuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STR FS PTHLH-PVALB GABA. http://purl.obolibrary.org/obo/UBERON_0010741 bone of pectoral complex http://purl.obolibrary.org/obo/UBERON_0010740 bone of appendage girdle complex A bone that is part of a pectoral complex. Examples: scapula, manus phalanx, any carpal bone, any bone of the pectoral fin. http://purl.obolibrary.org/obo/CL_4310121 striatal SST-LYPD6-RSPO2 GABAergic interneuron (Primate) http://purl.obolibrary.org/obo/CL_0011005 GABAergic interneuron A GABAergic interneuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STR LYPD6-RSPO2 GABA. http://purl.obolibrary.org/obo/UBERON_0010742 bone of pelvic complex http://purl.obolibrary.org/obo/UBERON_0010740 bone of appendage girdle complex A bone that is part of a pelvic complex. Examples: pubis, ischium, fot phalanx, any tarsal bone, any bone of the pelvic fin or girdle. http://purl.obolibrary.org/obo/CL_4310122 striatal SST-ADARB2 GABAergic interneuron (Primate) http://purl.obolibrary.org/obo/CL_4023017 sst GABAergic interneuron A sst GABAergic interneuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STR SST-ADARB2 GABA. http://purl.obolibrary.org/obo/UBERON_0010744 sacral vertebra pre-cartilage condensation http://purl.obolibrary.org/obo/UBERON_0015010 sacral vertebra endochondral element A sacral vertebra endochondral element that is composed primarily of a pre-cartilage condensation. http://purl.obolibrary.org/obo/UBERON_0010745 sacral vertebra cartilage element http://purl.obolibrary.org/obo/UBERON_2001457 postcranial axial cartilage A sacral vertebra endochondral element that is composed primarily of cartilage tissue. http://purl.obolibrary.org/obo/CL_4310123 striatal SST-CHODL GABAergic interneuron (Primate) http://purl.obolibrary.org/obo/CL_4023121 sst chodl GABAergic interneuron A sst chodl GABAergic interneuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STR SST-CHODL GABA. http://purl.obolibrary.org/obo/UBERON_0010748 lymph node follicle http://purl.obolibrary.org/obo/UBERON_0000444 lymphoid follicle A lymphoid follicle that is part of a lymph node. http://purl.obolibrary.org/obo/CL_4310124 striatal SST-RSPO2 GABAergic interneuron (Primate) http://purl.obolibrary.org/obo/CL_4023017 sst GABAergic interneuron A sst GABAergic interneuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STR SST-RSPO2 GABA. http://purl.obolibrary.org/obo/UBERON_0010753 lymph node secondary follicle http://purl.obolibrary.org/obo/UBERON_0010748 lymph node follicle A secondary follicle that is located in a lymph node. http://purl.obolibrary.org/obo/UBERON_0010754 germinal center http://purl.obolibrary.org/obo/UBERON_0001744 lymphoid tissue A collection of activated B cells at the center of a secondary follicle, formed after B cells become activated and migrate to the center. http://purl.obolibrary.org/obo/CL_4310125 STR TAC3-PLPP4 GABA TAC3-positive striatal interneuron (Primate) http://purl.obolibrary.org/obo/CL_4042001 TAC3-positive striatal interneuron A TAC3-positive striatal interneuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STR TAC3-PLPP4 GABA. http://purl.obolibrary.org/obo/UBERON_0010755 secondary follicle corona http://purl.obolibrary.org/obo/UBERON_0001744 lymphoid tissue The part of the secondary follicle that surrounds the germinal center. http://purl.obolibrary.org/obo/CL_4310126 STR-BF TAC3-PLPP4-LHX8 GABA TAC3-positive striatal interneuron (Primate) http://purl.obolibrary.org/obo/CL_4042001 TAC3-positive striatal interneuron A TAC3-positive striatal interneuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STR-BF TAC3-PLPP4-LHX8 GABA. http://purl.obolibrary.org/obo/UBERON_0010758 subdivision of organism along appendicular axis http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision A major subdivision of an organism that divides an organism along an axis perpedicular to the main body anterior-posterior axis. In vertebrates, this is typically a fin or limb segment. In insects, this includes segments of appendages such as antennae, as well as segments of the insect leg. http://purl.obolibrary.org/obo/UBERON_0010843 clavicle cartilage element http://purl.obolibrary.org/obo/UBERON_0005863 cartilaginous condensation A cartilaginous condensation that has the potential to develop into a clavicle. http://purl.obolibrary.org/obo/CL_4310127 striatal VIP GABAergic interneuron (Primate) http://purl.obolibrary.org/obo/CL_4023016 VIP GABAergic interneuron A VIP GABAergic interneuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:VIP GABA. http://purl.obolibrary.org/obo/UBERON_0010844 clavicle pre-cartilage condensation http://purl.obolibrary.org/obo/UBERON_0005866 pre-cartilage condensation A pre-cartilage condensation that has the potential to develop into a clavicle. http://purl.obolibrary.org/obo/CL_4310128 STRd cholinergic-GABAergic neuron (Primate) http://purl.obolibrary.org/obo/CL_0020007 dorso-striatal cholinergic-GABAergic neuron A dorso-striatal cholinergic-GABAergic neuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STRd Cholinergic GABA. http://purl.obolibrary.org/obo/UBERON_0010849 tibia cartilage element http://purl.obolibrary.org/obo/UBERON_0015004 tibia endochondral element A cartilaginous condensation that has the potential to develop into a tibia. http://purl.obolibrary.org/obo/CL_4310129 STRd D1 Matrix medium spiny neuron (Primate) http://purl.obolibrary.org/obo/CL_4030043 matrix D1 medium spiny neuron A matrix D1 medium spiny neuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STRd D1 Matrix MSN. http://purl.obolibrary.org/obo/UBERON_0010850 tibia pre-cartilage condensation http://purl.obolibrary.org/obo/UBERON_0015004 tibia endochondral element A pre-cartilage condensation that has the potential to develop into a tibia. http://purl.obolibrary.org/obo/CL_4310130 striosomal D1 medium spiny neuron (Primate) http://purl.obolibrary.org/obo/CL_4030048 striosomal D1 medium spiny neuron A striosomal D1 medium spiny neuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STRd D1 Striosome MSN. http://purl.obolibrary.org/obo/UBERON_0010851 fibula cartilage element http://purl.obolibrary.org/obo/UBERON_0015013 fibula endochondral element A cartilaginous condensation that has the potential to develop into a fibula. http://purl.obolibrary.org/obo/UBERON_0010852 fibula pre-cartilage condensation http://purl.obolibrary.org/obo/UBERON_0015013 fibula endochondral element A pre-cartilage condensation that has the potential to develop into a fibula. http://purl.obolibrary.org/obo/CL_4310131 STRd D1/D2-hybrid medium spiny neuron (Primate) http://purl.obolibrary.org/obo/CL_4030050 D1/D2-hybrid medium spiny neuron A D1/D2-hybrid medium spiny neuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STR D1D2 Hybrid MSN. http://purl.obolibrary.org/obo/UBERON_0010881 limb cartilage element http://purl.obolibrary.org/obo/UBERON_0015061 limb endochondral element A skeletal element that is part of a limb and composed of cartilage tissue. http://purl.obolibrary.org/obo/CL_4310132 STRd D2 Matrix medium spiny neuron (Primate) http://purl.obolibrary.org/obo/CL_4030047 matrix D2 medium spiny neuron A matrix D2 medium spiny neuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STRd D2 Matrix MSN. http://purl.obolibrary.org/obo/UBERON_0010882 limb bone pre-cartilage condensation http://purl.obolibrary.org/obo/UBERON_0015061 limb endochondral element A skeletal element that is part of a limb and composed of pre-cartilage tissue. http://purl.obolibrary.org/obo/UBERON_0010883 forelimb cartilage element http://purl.obolibrary.org/obo/UBERON_0015021 forelimb endochondral element A cartilaginous condensation that has the potential to develop into a forelimb bone. http://purl.obolibrary.org/obo/CL_4310133 STRd D2 Striomat hybrid medium spiny neuron (Primate) http://purl.obolibrary.org/obo/CL_4023029 indirect pathway medium spiny neuron A indirect pathway medium spiny neuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STRd D2 StrioMat Hybrid MSN. http://purl.obolibrary.org/obo/UBERON_0010884 forelimb bone pre-cartilage condensation http://purl.obolibrary.org/obo/UBERON_0015021 forelimb endochondral element A pre-cartilage condensation that has the potential to develop into a forelimb bone. http://purl.obolibrary.org/obo/CL_4310134 striosomal D2 medium spiny neuron (Primate) http://purl.obolibrary.org/obo/CL_4030049 striosomal D2 medium spiny neuron A striosomal D2 medium spiny neuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STRd D2 Striosome MSN. http://purl.obolibrary.org/obo/UBERON_0010885 hindlimb cartilage element http://purl.obolibrary.org/obo/UBERON_0015022 hindlimb endochondral element A cartilaginous condensation that has the potential to develop into a hindlimb bone. http://purl.obolibrary.org/obo/UBERON_0010886 hindlimb pre-cartilage condensation http://purl.obolibrary.org/obo/UBERON_0015022 hindlimb endochondral element A pre-cartilage condensation that has the potential to develop into a hindlimb bone. http://purl.obolibrary.org/obo/CL_4310135 STR cholinergic-GABAergic neuron (Primate) http://purl.obolibrary.org/obo/CL_0020008 striatal cholinergic-GABAergic neuron A striatal cholinergic-GABAergic neuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STR Cholinergic GABA. http://purl.obolibrary.org/obo/UBERON_0010890 pelvic complex muscle http://purl.obolibrary.org/obo/UBERON_0014892 skeletal muscle organ, vertebrate Muscles of the pelvic girdle, hindlimb or pelvic fin. http://purl.obolibrary.org/obo/CL_4310136 STRv D1 medium spiny neuron (Primate) http://purl.obolibrary.org/obo/CL_4030051 nucleus accumbens shell and olfactory tubercle D1 medium spiny neuron A nucleus accumbens shell and olfactory tubercle D1 medium spiny neuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STRv D1 MSN. http://purl.obolibrary.org/obo/UBERON_0010891 pectoral complex muscle http://purl.obolibrary.org/obo/UBERON_0014892 skeletal muscle organ, vertebrate A muscle of a pectoral girdle, pectoral fin or anterior limb. http://purl.obolibrary.org/obo/UBERON_0010893 median external naris http://purl.obolibrary.org/obo/UBERON_0005928 external naris Am unpaired external naris that lies in the midline of the head. http://purl.obolibrary.org/obo/CL_4310137 STRv D1-NUDAP medium spiny neuron (Primate) http://purl.obolibrary.org/obo/CL_4030054 D1-NUDAP medium spiny neuron A D1-NUDAP medium spiny neuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STRv D1 NUDAP MSN. http://purl.obolibrary.org/obo/UBERON_0010899 synchronous hermaphroditic organism http://purl.obolibrary.org/obo/UBERON_0007197 hermaphroditic organism Hermaphroditic organism that produces both male and female gametes at the same time. http://purl.obolibrary.org/obo/CL_4310138 STRv D2 medium spiny neuron (Primate) http://purl.obolibrary.org/obo/CL_4030052 nucleus accumbens shell and olfactory tubercle D2 medium spiny neuron A nucleus accumbens shell and olfactory tubercle D2 medium spiny neuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STRv D2 MSN. http://purl.obolibrary.org/obo/UBERON_0010905 clavicle bone primordium http://purl.obolibrary.org/obo/UBERON_0001048 primordium A primordium that develops into a clavicle bone. http://purl.obolibrary.org/obo/CL_4310143 ZI-HTH GABA GABAergic interneuron (Primate) http://purl.obolibrary.org/obo/CL_0011005 GABAergic interneuron A GABAergic interneuron of the Primates brain. These cells are located in the substantia nigra . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:ZI-HTH GABA. http://purl.obolibrary.org/obo/UBERON_0010911 ossicle http://purl.obolibrary.org/obo/UBERON_0004765 skeletal element Skeletal element that is often isolated, small, and variable in composition. http://purl.obolibrary.org/obo/UBERON_0010912 subdivision of skeleton http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision Anatomical cluster consisting of the skeletal elements (i.e. bone elements, cartilage elements, cartilage condensations) that are part of an individual subdivision of the organism. Excludes joints. http://purl.obolibrary.org/obo/CL_4310144 VTR-HTH Glut glutamatergic neuron of the basal ganglia (Primate) http://purl.obolibrary.org/obo/CL_0000700 dopaminergic neuron A glutamatergic neuron of the basal ganglia of the Primates brain. These cells are located in the striatum, subthalamic nucleus, substantia nigra . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:VTR-HTH Glut. http://purl.obolibrary.org/obo/UBERON_0010913 vertebral element http://purl.obolibrary.org/obo/UBERON_0004765 skeletal element Skeletal element that forms around the notochord and is part of the vertebral column. http://purl.obolibrary.org/obo/CL_4310145 AMY-SLEA-BNST D1 GABA GABAergic interneuron (Primate) http://purl.obolibrary.org/obo/CL_0011005 GABAergic interneuron A GABAergic interneuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:AMY-SLEA-BNST D1 GABA. http://purl.obolibrary.org/obo/UBERON_0010948 cleidooccipital muscle http://purl.obolibrary.org/obo/UBERON_0014892 skeletal muscle organ, vertebrate A muscle organ that attaches_to a clavicle and attaches_to a occipital bone. http://purl.obolibrary.org/obo/CL_4310146 AMY-SLEA-BNST GABA GABAergic interneuron (Primate) http://purl.obolibrary.org/obo/CL_0011005 GABAergic interneuron A GABAergic interneuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:AMY-SLEA-BNST GABA. http://purl.obolibrary.org/obo/UBERON_0010949 sternooccipital muscle http://purl.obolibrary.org/obo/UBERON_0002377 muscle of neck A muscle organ that has_muscle_insertion a occipital bone and has_muscle_origin a sternum. http://purl.obolibrary.org/obo/UBERON_0010959 craniocervical muscle http://purl.obolibrary.org/obo/UBERON_0014892 skeletal muscle organ, vertebrate Any muscle organ that is part of either the head or the neck. http://purl.obolibrary.org/obo/CL_4310147 OB Dopa-GABA neuron (Primate) http://purl.obolibrary.org/obo/CL_0020006 OB-Dopa-GABA A OB-Dopa-GABA of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:OB Dopa-GABA. http://purl.obolibrary.org/obo/UBERON_0011004 pharyngeal arch cartilage http://purl.obolibrary.org/obo/UBERON_0003933 cranial cartilage A cartilage element that is part of a splanchnocranium. http://purl.obolibrary.org/obo/CL_4310148 OB FRMD7 GABA GABAergic neuron (Primate) http://purl.obolibrary.org/obo/CL_0000617 GABAergic neuron A GABAergic neuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:OB FRMD7 GABA. http://purl.obolibrary.org/obo/UBERON_0011060 perilymphatic channel http://purl.obolibrary.org/obo/UBERON_0000025 tube A channel containing perilymph passing through the temporal bone, connecting the scala tympani of the cochlea to the subarachnoid space. http://purl.obolibrary.org/obo/CL_0020029 cuboidal epithelial cell http://purl.obolibrary.org/obo/CL_0000075 columnar/cuboidal epithelial cell An epithelial cell that has a cuboidal morphology. http://purl.obolibrary.org/obo/UBERON_0011085 palatoquadrate arch http://purl.obolibrary.org/obo/UBERON_0010912 subdivision of skeleton The dorsal portion of the first pharyngeal arch, comprising the upper jaw[ZFIN,VHOG]. http://purl.obolibrary.org/obo/CL_0020035 intestinal intraepithelial lymphocyte http://purl.obolibrary.org/obo/CL_0002496 intraepithelial lymphocyte A T cell that is located in the intestinal epithelium and is capable of a mucosal immune response. http://purl.obolibrary.org/obo/UBERON_0011088 ligament of knee joint http://purl.obolibrary.org/obo/UBERON_0008846 skeletal ligament A ligament that is part of a knee joint. http://purl.obolibrary.org/obo/UBERON_0011090 skeleton of right pelvic girdle http://purl.obolibrary.org/obo/UBERON_0007832 pelvic girdle skeleton A skeleton of pelvic girdle that is part of a right pelvic girdle region. http://purl.obolibrary.org/obo/CL_0020030 CD4-positive exhausted alpha-beta T cell http://purl.obolibrary.org/obo/CL_0000624 CD4-positive, alpha-beta T cell A CD4-positive alpha-beta T cell that displays impaired function and altered differentiation as a result of chronic antigenic stimulation (e.g., chronic infection, tumors, or persistent inflammation). This state is characterised by sustained expression of PD-1 as a shared feature. Additional exhaustion-associated molecules, including the transcription factor TOX, and context- or stage-dependent changes in markers such as LAG-3, TIM-3, CD39, and T-bet, may also be observed; however, the expression levels of these molecules vary depending on exhaustion stage and tissue environment. http://purl.obolibrary.org/obo/UBERON_0011091 skeleton of left pelvic girdle http://purl.obolibrary.org/obo/UBERON_0007832 pelvic girdle skeleton A skeleton of pelvic girdle that is part of a left pelvic girdle region. http://purl.obolibrary.org/obo/UBERON_0011092 right pelvic girdle region http://purl.obolibrary.org/obo/UBERON_0001271 pelvic girdle region A pelvic girdle region that is in the right side of a multicellular organism. http://purl.obolibrary.org/obo/CL_0020028 hybrid osteochondral skeletal cell http://purl.obolibrary.org/obo/CL_0007001 skeletogenic cell A skeletal cell at the periosteal surface of the murine rib that displays hybrid osteochondral properties, emerging within the large callus that bridges segmental rib defects. It derives from a Sox9-expressing periosteal skeletal stem/progenitor subpopulation that constitutes only a small fraction of uninjured rib periosteum. After injury, these cells populate the callus and co-express cartilage and bone regulators Sox9 and Runx2, as well as matrix genes Col2a1 and Col1a1, while exhibiting dual chondrocyte/osteoblast properties. http://purl.obolibrary.org/obo/UBERON_0011093 left pelvic girdle region http://purl.obolibrary.org/obo/UBERON_0001271 pelvic girdle region A pelvic girdle region that is in the left side of a multicellular organism. http://purl.obolibrary.org/obo/UBERON_0011094 vertebra cartilage element http://purl.obolibrary.org/obo/UBERON_0010913 vertebral element The cartilaginous form of a vertebral element, a skeletal element that forms around the notochord and is part of the vertebral column. http://purl.obolibrary.org/obo/CL_0020031 CD8-positive exhausted alpha-beta T cell http://purl.obolibrary.org/obo/CL_0000625 CD8-positive, alpha-beta T cell A CD8-positive alpha-beta T cell that displays impaired function and altered differentiation as a result of chronic antigenic stimulation (e.g., chronic infection, tumours, or persistent inflammation). This state is characterised by sustained expression of PD-1 as a shared feature. Additional exhaustion-associated molecules, including expression of the transcription factor TOX and reduced T-bet, and context- or stage-dependent changes in markers such as LAG-3, TIM-3, CD39, and EOMES, may also be observed; however, the expression levels of these molecules vary depending on exhaustion stage and disease context. http://purl.obolibrary.org/obo/UBERON_0011095 vertebra pre-cartilage condensation http://purl.obolibrary.org/obo/UBERON_0010913 vertebral element The pre-cartilaginous form of a vertebral element, a skeletal element that forms around the notochord and is part of the vertebral column. http://purl.obolibrary.org/obo/UBERON_0011096 lacrimal nerve http://purl.obolibrary.org/obo/UBERON_0011779 nerve of head region The lacrimal nerve is the smallest of the three branches of the ophthalmic division of the trigeminal nerve. http://purl.obolibrary.org/obo/CL_0020032 oRGC2 http://purl.obolibrary.org/obo/CL_0000740 retinal ganglion cell A conserved retinal ganglion cell orthotype whose transcriptomic profile groups together ON parasol RGCs from primate foveal and peripheral retina with their molecularly homologous mouse α RGC subtype (ON-transient α RGC, C41) (Hahn et al., 2023; Tran et al., 2019). Reference to the transcriptomic evidence is found at: GSE237215. http://purl.obolibrary.org/obo/UBERON_0011107 synovial joint of pelvic girdle http://purl.obolibrary.org/obo/UBERON_0008114 joint of girdle A synovial joint that is part of a pelvic girdle region. http://purl.obolibrary.org/obo/UBERON_0011108 synovial joint of pectoral girdle http://purl.obolibrary.org/obo/UBERON_0008114 joint of girdle A synovial joint that is part of a pectoral girdle region. http://purl.obolibrary.org/obo/CL_0020033 stem cell memory CD4-positive, alpha-beta T cell http://purl.obolibrary.org/obo/CL_0000897 CD4-positive, alpha-beta memory T cell A CD4-positive memory alpha-beta T cell with stem-like properties that is long-lived, retains a naïve-like phenotype, and exhibits self-renewal and multipotent differentiation capacity. This cell acts as a stem-like reservoir capable of regenerating central and effector memory T cell subsets. http://purl.obolibrary.org/obo/UBERON_0011112 tibiofibular joint http://purl.obolibrary.org/obo/UBERON_0003840 hindlimb joint A joint that connects the tibia and the fibula. http://purl.obolibrary.org/obo/UBERON_0011118 tarsometatarsal joint http://purl.obolibrary.org/obo/UBERON_0001487 pes joint The tarsometatarsal articulations are arthrodial joints in the pes. http://purl.obolibrary.org/obo/CL_0020034 stem cell memory CD8-positive, alpha-beta T cell http://purl.obolibrary.org/obo/CL_0000909 CD8-positive, alpha-beta memory T cell A CD8-positive memory alpha-beta T cell with stem-like properties that is long-lived, retains a naïve-like phenotype, and exhibits self-renewal and multipotent differentiation capacity. This cell acts as a stem-like reservoir capable of regenerating central and effector memory T cell subsets. http://purl.obolibrary.org/obo/UBERON_0011119 carpometacarpal joint http://purl.obolibrary.org/obo/UBERON_0001489 manus joint The carpometacarpal joints (CMC) are joints in the wrist that articulates the distal row of carpal bones and the proximal bases of the metacarpal bones. http://purl.obolibrary.org/obo/UBERON_0011120 laryngeal joint http://purl.obolibrary.org/obo/UBERON_0002217 synovial joint A skeletal joint that connects a laryngeal cartilage. http://purl.obolibrary.org/obo/CL_0020036 oRGC1 http://purl.obolibrary.org/obo/CL_0000740 retinal ganglion cell A conserved retinal ganglion cell orthotype whose transcriptomic profile groups together OFF midget RGCs from primate foveal and peripheral retina with their molecularly homologous mouse alpha RGC subtype (OFF-sustained alpha-RGC, C42) (Hahn et al., 2023; Tran et al., 2019). Reference to the transcriptomic evidence is found at: GSE237215. http://purl.obolibrary.org/obo/UBERON_0011131 intermetacarpal joint http://purl.obolibrary.org/obo/UBERON_0001489 manus joint A skeletal joint that connects two adjacent metacarpals[FMA,modified]. http://purl.obolibrary.org/obo/UBERON_0011132 intercarpal joint http://purl.obolibrary.org/obo/UBERON_0001489 manus joint A skeletal joint that connects two carpal bones. http://purl.obolibrary.org/obo/CL_0020037 superficial zone articular chondrocyte http://purl.obolibrary.org/obo/CL_1001607 articular chondrocyte An articular chondrocyte located in the most superficial zone of articular cartilage, characterized by flattened morphology and tangential alignment parallel to the joint surface, and residing within a matrix of fine collagen fibrils and relatively low proteoglycan content. In mice and humans, this cell typically expresses lubricin (PRG4) and contributes to lubrication and resistance to shear and tensile forces at the cartilage surface. http://purl.obolibrary.org/obo/UBERON_0011133 intermetatarsal joint http://purl.obolibrary.org/obo/UBERON_0001487 pes joint A joint that connects two adjacent metatarsals. http://purl.obolibrary.org/obo/UBERON_0011134 nonsynovial joint http://purl.obolibrary.org/obo/UBERON_0000982 skeletal joint Joint in which the articulating bones or cartilages are connected by ligaments or fibrocartilage without an intervening synovial cavity. Examples: sagittal suture, inferior tibiofibular syndesmosis, costochondral joint, pubic symphysis. http://purl.obolibrary.org/obo/CL_0020038 middle zone articular chondrocyte http://purl.obolibrary.org/obo/CL_1001607 articular chondrocyte An articular chondrocyte located in the middle (transitional) zone of articular cartilage, characterized by round morphology and relatively random spatial organization, and residing in a matrix enriched in proteoglycans and thicker collagen fibrils oriented obliquely to the articular surface. This cell contributes to the largest volume fraction of articular cartilage and functions primarily in distributing and absorbing compressive loads between the superficial and deep zones. http://purl.obolibrary.org/obo/UBERON_0011135 intervertebral cartilage http://purl.obolibrary.org/obo/UBERON_0007844 cartilage element A cartilage element that lies between two successive vertebral centra. http://purl.obolibrary.org/obo/UBERON_0011136 ligament of vertebral column http://purl.obolibrary.org/obo/UBERON_0008846 skeletal ligament Ligament that joins successive centra. Important in controlling the stiffness of the vertebral column when it flexes. http://purl.obolibrary.org/obo/CL_0020039 deep zone articular chondrocyte http://purl.obolibrary.org/obo/CL_1001607 articular chondrocyte An articular chondrocyte located in the deep (radial) zone of articular cartilage, characterized by columnar arrangement perpendicular to the joint surface and residence within a matrix containing the highest proteoglycan concentration and large-diameter collagen fibrils oriented radially. In humans, this cell expresses collagen type X (COL10A1) and provides maximal resistance to compressive forces. It is positioned adjacent to the tidemark, where collagen fibrils extend into the calcified cartilage to anchor the articular cartilage to subchondral bone. http://purl.obolibrary.org/obo/UBERON_0011137 axial skeletal system http://purl.obolibrary.org/obo/UBERON_0000075 subdivision of skeletal system Subdivision of the skeletal system which consists of the axial skeleton plus associated joints. http://purl.obolibrary.org/obo/UBERON_0011138 postcranial axial skeletal system http://purl.obolibrary.org/obo/UBERON_0000075 subdivision of skeletal system Subdivision of the skeletal system which consists of the postcranial axial skeleton plus associated joints. http://purl.obolibrary.org/obo/CL_0020040 calcified zone articular chondrocyte http://purl.obolibrary.org/obo/CL_1001607 articular chondrocyte An articular chondrocyte located in the calcified cartilage zone below the tidemark at the interface between articular cartilage and subchondral bone, embedded within a mineralized extracellular matrix. In humans, this cell exhibits a hypertrophic-like phenotype and typically expresses collagen type X (COL10A1). Together with the surrounding calcified matrix, it forms a transitional region that mechanically couples the deep articular cartilage to the underlying subchondral bone. http://purl.obolibrary.org/obo/UBERON_0011139 synovial limb joint http://purl.obolibrary.org/obo/UBERON_0003657 limb joint Any synovial joint that is part of a (free) limb. http://purl.obolibrary.org/obo/UBERON_0011141 appendicular ossicle http://purl.obolibrary.org/obo/UBERON_0010911 ossicle Ossicle that is part of the appendicular skeleton. http://purl.obolibrary.org/obo/CL_0020041 oRGC4 http://purl.obolibrary.org/obo/CL_0000740 retinal ganglion cell A conserved retinal ganglion cell orthotype whose transcriptomic profile groups together ON midget RGCs from primate foveal and peripheral retina with their molecularly homologous mouse alpha RGC subtype (ON-sustained α RGC, C43) (Hahn et al., 2023; Tran et al., 2019). Reference to the transcriptomic evidence is found at: GSE237215. http://purl.obolibrary.org/obo/UBERON_0011142 axial ossicle http://purl.obolibrary.org/obo/UBERON_0010911 ossicle Ossicle that is part of the axial skeleton. http://purl.obolibrary.org/obo/UBERON_0011143 upper urinary tract http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure Subdivision of urinary system which consists of the kidney and the ureters. http://purl.obolibrary.org/obo/CL_0020042 oRGC5 http://purl.obolibrary.org/obo/CL_0000740 retinal ganglion cell A conserved retinal ganglion cell orthotype whose transcriptomic profile groups together OFF parasol RGCs from primate foveal and peripheral retina with their molecularly homologous mouse α RGC subtype (OFF-transient α RGC, C45) (Hahn et al., 2023; Tran et al., 2019). Reference to transcriptomic evidence can be found at: GSE237215. http://purl.obolibrary.org/obo/UBERON_0011148 submucosal gland http://purl.obolibrary.org/obo/UBERON_0000414 mucous gland Gland of the lamina epithelialis mucosae which perforate the lamina muscularis, with their adenomeres located in the submucosal connective tissue. http://purl.obolibrary.org/obo/UBERON_0011156 facial skeleton http://purl.obolibrary.org/obo/UBERON_0011158 primary subdivision of skull Subdivision of skull that consists of the facial bones. http://purl.obolibrary.org/obo/CL_0020043 fasciacyte http://purl.obolibrary.org/obo/CL_0000499 stromal cell A mesenchymal stromal cell of the deep fascia (e.g., fascia lata) that is vimentin-positive, CD68-negative, and S-100A4-positive, organized in small clusters at the interface between fibrous fascial sublayers and loose connective tissue. It is specialized for hyaluronan-rich ECM biosynthesis, as evidenced by HAS2 mRNA expression, Alcian Blue staining, and anti-HABP immunoreactivity, and functions to regulate fascial gliding and viscoelasticity. http://purl.obolibrary.org/obo/UBERON_0011158 primary subdivision of skull http://purl.obolibrary.org/obo/UBERON_0000075 subdivision of skeletal system The skull can be divided into two: the neurocranium and the facial skeleton. http://purl.obolibrary.org/obo/UBERON_0011164 neurocranium bone http://purl.obolibrary.org/obo/UBERON_0004766 cranial bone A bone that is part of a neurocranium [Automatically generated definition]. http://purl.obolibrary.org/obo/CL_0020044 migratory muscle precursor http://purl.obolibrary.org/obo/CL_0000680 muscle precursor cell Muscle precursor cells that delaminate from the dermomyotome after epithelial-to-mesenchymal transition (EMT) and undergo long-range migration while retaining proliferative capacity. http://purl.obolibrary.org/obo/UBERON_0011171 joint connecting upper and lower jaws http://purl.obolibrary.org/obo/UBERON_0002217 synovial joint Synovial joint that articulates bones of upper and lower jaw. http://purl.obolibrary.org/obo/UBERON_0011172 retrorubral area of midbrain reticular nucleus http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain The term retrorubral area of the midbrain reticular nucleus refers to a region of the rat brain caudal and dorsal to the ventral tegmental area. It is one of three parts of the midbrain reticular nucleus; the other two are the magnocellular part of the midbrain reticular nucleus and the parvicellular part of the midbrain reticular nucleus (Swanson-2004). BrainInfo distinguishes between the Retrorubral area of the midbrain reticular formation and the retrorubral nucleus. http://purl.obolibrary.org/obo/CL_0020045 Dogiel type II neuron http://purl.obolibrary.org/obo/CL_0007011 enteric neuron A neuron characterised by Dogiel type II morphology: a large, smooth, oval soma bearing multiple long axon-like processes (multiaxonal) that extend without branching until they reach their targets. The soma lacks the short lamellar or spiny dendrites characteristic of Dogiel type I neurons. Dogiel type II neurons were first described by Alexander Dogiel in 1899 based on methylene blue staining in gastrointestinal ganglia. In the enteric nervous system, Dogiel type II neurons correspond to intrinsic primary afferent neurons (IPANs) and exhibit AH-type electrophysiology (prolonged afterhyperpolarization following an action potential). http://purl.obolibrary.org/obo/UBERON_0011184 epithelium of crypt of Lieberkuhn http://purl.obolibrary.org/obo/UBERON_0001277 intestinal epithelium An epithelium that is part of a crypt of Lieberkuhn. http://purl.obolibrary.org/obo/UBERON_0011185 gastrointestinal sphincter http://purl.obolibrary.org/obo/UBERON_0013765 digestive system element A sphincter muscle that is part of the gastrointestinal system. http://purl.obolibrary.org/obo/CL_0020046 intrinsic primary afferent neuron of myenteric plexus http://purl.obolibrary.org/obo/CL_3000004 peripheral sensory neuron A sensory neuron of the enteric nervous system whose soma resides in the myenteric plexus and which functions as the afferent limb of intrinsic reflex circuits controlling motility, secretion, and blood flow. This neuron is characterised by Dogiel type II morphology (large smooth soma with multiple long axon-like processes), AH-type electrophysiology (prolonged afterhyperpolarization following an action potential), and is immunopositive for choline acetyltransferase (ChAT) and immunonegative for neuronal nitric oxide synthase (NOS1). http://purl.obolibrary.org/obo/UBERON_0011189 lamina propria of large intestine http://purl.obolibrary.org/obo/UBERON_0004780 gastrointestinal system lamina propria A lamina propria that is part of a large intestine. http://purl.obolibrary.org/obo/UBERON_0011191 ophthalmic vein http://purl.obolibrary.org/obo/UBERON_0009141 craniocervical region vein Ophthalmic veins are veins which drain the eye. More specifically, they can refer to: Superior ophthalmic vein Inferior ophthalmic vein. http://purl.obolibrary.org/obo/CL_0020047 interneuron of myenteric plexus http://purl.obolibrary.org/obo/CL_0007011 enteric neuron An interneuron of the enteric nervous system whose soma resides in the myenteric plexus. Interneurons of the myenteric plexus integrate sensory input from intrinsic primary afferent neurons (IPANs) and modulate motor output to smooth muscle and secretory epithelia by synapsing onto motor neurons and other interneurons within the plexus. http://purl.obolibrary.org/obo/UBERON_0011192 superior ophthalmic vein http://purl.obolibrary.org/obo/UBERON_0011191 ophthalmic vein The superior ophthalmic vein begins at the inner angle of the orbit in a vein named the nasofrontal which communicates anteriorly with the angular vein; it pursues the same course as the ophthalmic artery, and receives tributaries corresponding to the branches of that vessel. Forming a short single trunk, it passes between the two heads of the Rectus lateralis and through the medial part of the superior orbital fissure, and ends in the cavernous sinus. The ethmoidal veins drain into the superior ophthalmic vein. Vorticose veins also drain into the superior ophthalmic vein. http://purl.obolibrary.org/obo/CL_0020048 secretomotor/vasodilator neuron of myenteric plexus http://purl.obolibrary.org/obo/CL_0007011 enteric neuron An enteric neuron whose soma resides in the myenteric plexus and which controls mucosal secretion and blood flow by innervating secretory epithelia and submucosal blood vessels. This neuron is characterised by expression of vasoactive intestinal peptide (VIP). In mouse, two Glp2r+ subtypes have been identified: PSVN1 (VIP+, non-cholinergic) and PSVN2 (ChAT+, cholinergic). In human, only the VIP+ non-cholinergic subtype has been detected. http://purl.obolibrary.org/obo/UBERON_0011197 parathyroid epithelium http://purl.obolibrary.org/obo/UBERON_0005911 endo-epithelium An epithelium that is part of a parathyroid gland. http://purl.obolibrary.org/obo/UBERON_0011198 muscle layer of large intestine http://purl.obolibrary.org/obo/UBERON_0012367 muscle layer of intestine A muscle layer that is part of a large intestine. http://purl.obolibrary.org/obo/CL_0020049 intestinofugal neuron http://purl.obolibrary.org/obo/CL_0007011 enteric neuron An enteric neuron whose soma resides in the myenteric plexus of the intestine and whose axon projects outside the gut wall to synapse on neurons in prevertebral sympathetic ganglia (celiac, superior mesenteric, or inferior mesenteric ganglia). This neuron provides a pathway for gut-to-brain communication via sympathetic prevertebral ganglia. In humans, 89% are immunopositive for choline acetyltransferase (ChAT); CART (cocaine- and amphetamine-regulated transcript) is NOT a human marker (0% CART+) but is present in rodent viscerofugal neurons. http://purl.obolibrary.org/obo/UBERON_0011201 muscle layer of small intestine http://purl.obolibrary.org/obo/UBERON_0012367 muscle layer of intestine A muscle layer that is part of a small intestine. http://purl.obolibrary.org/obo/UBERON_0011213 root of vagus nerve http://purl.obolibrary.org/obo/UBERON_0002211 nerve root A root of cranial nerve that is part of a vagus nerve. http://purl.obolibrary.org/obo/CL_0020050 ascending interneuron of myenteric plexus http://purl.obolibrary.org/obo/CL_0020047 interneuron of myenteric plexus An interneuron of the myenteric plexus whose axon projects orally (in the ascending direction) along the gut axis. This neuron is immunopositive for choline acetyltransferase (ChAT) and enkephalin (ENK), and forms the excitatory limb of ascending reflex pathways that coordinate peristalsis. http://purl.obolibrary.org/obo/UBERON_0011214 nucleus of midbrain tectum http://purl.obolibrary.org/obo/UBERON_0009661 midbrain nucleus A neural nucleus that is part of a midbrain tectum. http://purl.obolibrary.org/obo/UBERON_0011215 central nervous system cell part cluster http://purl.obolibrary.org/obo/UBERON_0005162 multi cell part structure A multi cell part structure that is part of a central nervous system. http://purl.obolibrary.org/obo/CL_0020051 descending interneuron of myenteric plexus http://purl.obolibrary.org/obo/CL_0020047 interneuron of myenteric plexus An interneuron of the myenteric plexus whose axon projects aborally (in the descending direction) along the gut axis. This neuron class encompasses multiple chemically diverse subtypes including serotonergic (5-HT+), nitrergic (NOS1+), and other populations, forming the inhibitory limb of descending reflex pathways. http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision http://purl.obolibrary.org/obo/UBERON_0010000 multicellular anatomical structure A subdivision of an anatomical system. http://purl.obolibrary.org/obo/UBERON_0011233 synovial membrane of synovial tendon sheath http://purl.obolibrary.org/obo/UBERON_0007616 layer of synovial tissue Synovial sac which surrounds parts of one or more tendons. Examples: synovial tendon sheath of manual digit 2, radial bursa. http://purl.obolibrary.org/obo/CL_0020052 stubby Dogiel type I neuron of myenteric plexus http://purl.obolibrary.org/obo/CL_4047038 dogiel type I neuron A Dogiel type I neuron of the myenteric plexus characterised by stubby (lamellar) dendrite morphology with broad, flattened dendritic expansions. This neuron is immunopositive for choline acetyltransferase (ChAT) and immunonegative for neuronal nitric oxide synthase (NOS1), corresponding to excitatory motor neurons of the enteric nervous system. http://purl.obolibrary.org/obo/UBERON_0011236 deep fascia http://purl.obolibrary.org/obo/UBERON_0008982 fascia Deep fascia (or 'investing fascia') is a layer of fascia which can surround individual muscles, and divide groups of muscles into compartments. This is the dense fibrous connective tissue that interpenetrates and surrounds the muscles, bones, nerves and blood vessels of the body. It provides connection and communication in the form of aponeuroses, ligaments, tendons, retinacula, joint capsules, and septa. The deep fasciae envelop all bone; cartilage, and blood vessels and become specialized in muscles and nerves. The high density of collagen fibers is what gives the deep fascia its strength and integrity. The amount of elastin fiber determines how much extensibility and resilience it will have. http://purl.obolibrary.org/obo/CL_0020053 spiny Dogiel type I neuron of myenteric plexus http://purl.obolibrary.org/obo/CL_4047038 dogiel type I neuron A Dogiel type I neuron of the myenteric plexus characterised by spiny (spine-like) dendrite morphology with numerous short projections along the dendrites. This neuron is immunopositive for neuronal nitric oxide synthase (NOS1) and immunonegative for choline acetyltransferase (ChAT), corresponding to inhibitory motor neurons of the enteric nervous system. http://purl.obolibrary.org/obo/UBERON_0011241 ethmoid region http://purl.obolibrary.org/obo/UBERON_0034921 multi organ part structure The most anterior region of the braincase. Provides structural support for peripheral olfactory organ. http://purl.obolibrary.org/obo/CL_0020054 Dogiel type II neuron of myenteric plexus http://purl.obolibrary.org/obo/CL_0020046 intrinsic primary afferent neuron of myenteric plexus An intrinsic primary afferent neuron of the myenteric plexus characterised by Dogiel type II morphology: a large, smooth, oval soma bearing multiple long axon-like processes that extend without branching until they reach their targets in both the myenteric and submucosal plexuses and the mucosa. The soma lacks the dendrites characteristic of Dogiel type I neurons and is larger in cross-sectional area than either motor neuron type. This neuron is immunopositive for choline acetyltransferase (ChAT) and immunonegative for neuronal nitric oxide synthase (NOS1). It exhibits AH-type electrophysiology, characterised by a prolonged afterhyperpolarization (AHP) following an action potential. Substance P (encoded by TAC1) expression has been reported in subsets across species. http://purl.obolibrary.org/obo/UBERON_0011249 appendicular skeletal system http://purl.obolibrary.org/obo/UBERON_0000075 subdivision of skeletal system Subdivision of the skeletal system which consists of the appendicular skeleton plus associated joints. http://purl.obolibrary.org/obo/CL_0020055 calretinin-positive intrinsic primary afferent neuron of myenteric plexus http://purl.obolibrary.org/obo/CL_0020046 intrinsic primary afferent neuron of myenteric plexus An intrinsic primary afferent neuron of the myenteric plexus that is immunopositive for calretinin. This neuron shares the Dogiel type II morphology and AH-type electrophysiology of all myenteric IPANs, and is immunopositive for choline acetyltransferase (ChAT) and immunonegative for neuronal nitric oxide synthase (NOS1). http://purl.obolibrary.org/obo/UBERON_0011250 autopod bone http://purl.obolibrary.org/obo/UBERON_0015063 autopod endochondral element A bone that is part of a autopod region. Note that this incudes the carpal and tarsal bones. http://purl.obolibrary.org/obo/CL_0020056 calretinin-negative intrinsic primary afferent neuron of myenteric plexus http://purl.obolibrary.org/obo/CL_0020046 intrinsic primary afferent neuron of myenteric plexus An intrinsic primary afferent neuron of the myenteric plexus that lacks calretinin expression. This neuron shares the Dogiel type II morphology and AH-type electrophysiology of all myenteric IPANs, and is immunopositive for choline acetyltransferase (ChAT) and immunonegative for neuronal nitric oxide synthase (NOS1). http://purl.obolibrary.org/obo/UBERON_0011270 dorsal trunk http://purl.obolibrary.org/obo/UBERON_0009569 subdivision of trunk The part of the trunk that is in the dorsum[cjm]. http://purl.obolibrary.org/obo/CL_0020057 cholinergic neuron of myenteric plexus http://purl.obolibrary.org/obo/CL_0007011 enteric neuron An enteric neuron whose soma resides in the myenteric plexus and which is capable of acetylcholine secretion, neurotransmission. This is a defined grouping class that autoclassifies stubby Dogiel type I neurons, intrinsic primary afferent neurons, ascending interneurons, and their morphological/chemical subterms. http://purl.obolibrary.org/obo/UBERON_0011289 pharyngobasilar fascia http://purl.obolibrary.org/obo/UBERON_0006614 aponeurosis The pharyngeal aponeurosis (or pharyngobasilar fascia, or fibrous coat), is situated between the mucous and muscular layers. It is thick above where the muscular fibers are wanting, and is firmly connected to the basilar portion of the occipital and the petrous portions of the temporal bones. As it descends it diminishes in thickness, and is gradually lost. It is strengthened posteriorly by a strong fibrous band, which is attached above to the pharyngeal spine on the under surface of the basilar portion of the occipital bone, and passes downward, forming a median raphe, which gives attachment to the Constrictores pharyngis. http://purl.obolibrary.org/obo/CL_0020058 nitrergic neuron of myenteric plexus http://purl.obolibrary.org/obo/CL_0007011 enteric neuron An enteric neuron whose soma resides in the myenteric plexus and which is capable of nitric oxide biosynthetic process. This is a defined grouping class that autoclassifies spiny Dogiel type I neurons (the nitrergic motor neuron morphotype). http://purl.obolibrary.org/obo/UBERON_0011298 submucosa of fallopian tube http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure The submucous layer of the wall of the uterine tube. http://purl.obolibrary.org/obo/CL_4033175 dorsal root ganglion BRN3A neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A sensory neuron that has the soma located in the dorsal root ganglion and expresses the pan-sensory transcription factor POU domain, class 4, transcription factor 1 (BRN3A/POU4F1). In humans, BRN3A is expressed by approximately 98% of DRG neurons and serves as a broad marker for the sensory neuron population. http://purl.obolibrary.org/obo/UBERON_0011299 white matter of telencephalon http://purl.obolibrary.org/obo/UBERON_0019261 white matter of forebrain A partion of white matter that is part of a telencephalon. This can be further subdivided in some species, for example, into hemisphere white matter and the corpus callosum. http://purl.obolibrary.org/obo/CL_4033176 dorsal root ganglion CGRP neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A sensory neuron that has the soma located in the dorsal root ganglion and expresses the marker calcitonin gene-related peptide (CGRP). This peptidergic nociceptor subpopulation is involved in neurogenic inflammation and pain signaling. http://purl.obolibrary.org/obo/UBERON_0011300 gray matter of telencephalon http://purl.obolibrary.org/obo/UBERON_0019264 gray matter of forebrain A portion of gray matter that is part of a telencephalon. http://purl.obolibrary.org/obo/CL_4033177 dorsal root ganglion EDN1 neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A sensory neuron that has the soma located in the dorsal root ganglion and expresses the marker endothelin-1 (EDN1). Endothelin signaling in DRG neurons has been demonstrated in rat tissue. http://purl.obolibrary.org/obo/UBERON_0011357 Reissner's fiber http://purl.obolibrary.org/obo/UBERON_0000476 acellular anatomical structure An acellular strand that runs from subcommissural organ caudally through the ventricular system and central canal to the ampulla caudalis. Develops from glycoproteins secreted into CSF. http://purl.obolibrary.org/obo/CL_4033178 dorsal root ganglion Nav1.7 neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A sensory neuron that has the soma located in the dorsal root ganglion and expresses the marker sodium channel protein type 9 subunit alpha (Nav1.7/SCN9A). Nav1.7 accounts for approximately 50% of total sodium channel expression in human DRG and is present in 54-57% of TrkA-positive nociceptors. http://purl.obolibrary.org/obo/UBERON_0011362 cranial blood vasculature http://purl.obolibrary.org/obo/UBERON_0004537 blood vasculature A blood vasculature that is part of a head. http://purl.obolibrary.org/obo/CL_4033179 dorsal root ganglion Nav1.9 neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A sensory neuron that has the soma located in the dorsal root ganglion and expresses the marker sodium channel protein type 11 subunit alpha (Nav1.9/SCN11A). Nav1.9 is present in approximately 26% of TrkA-positive human DRG neurons and defines a nociceptor subpopulation. http://purl.obolibrary.org/obo/UBERON_0011363 cranial lymph vasculature http://purl.obolibrary.org/obo/UBERON_0004536 lymph vasculature A lymph vasculature that is part of a head. http://purl.obolibrary.org/obo/CL_4033180 dorsal root ganglion peripherin neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A sensory neuron that has the soma located in the dorsal root ganglion and expresses the intermediate filament protein peripherin (PRPH). Peripherin marks small-diameter unmyelinated C-fiber neurons in the DRG. http://purl.obolibrary.org/obo/UBERON_0011370 transverse process of atlas http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure A transverse process of vertebra that is part of a vertebral bone 1. http://purl.obolibrary.org/obo/CL_4033181 dorsal root ganglion Piezo2 neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A sensory neuron that has the soma located in the dorsal root ganglion and expresses the marker piezo-type mechanosensitive ion channel component 2 (Piezo2). Piezo2 is the primary mechanotransduction channel and is present in approximately 35% of TrkA-positive human DRG neurons. http://purl.obolibrary.org/obo/UBERON_0011375 skin of prepuce of clitoris http://purl.obolibrary.org/obo/UBERON_0005298 skin of clitoris A zone of skin that is part of a prepuce of clitoris. http://purl.obolibrary.org/obo/CL_4033182 dorsal root ganglion RET neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A sensory neuron that has the soma located in the dorsal root ganglion and expresses the marker proto-oncogene tyrosine-protein kinase receptor Ret (RET). RET is present in approximately 46% of TrkA-positive human DRG neurons and marks the non-peptidergic nociceptor population. http://purl.obolibrary.org/obo/UBERON_0011566 lumen of esophagus http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space An anatomical cavity that is part of a esophagus. http://purl.obolibrary.org/obo/CL_4033183 dorsal root ganglion SP neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A sensory neuron that has the soma located in the dorsal root ganglion and expresses the marker protachykinin-1 (substance P). This peptidergic nociceptor subpopulation is involved in pain signaling and neurogenic inflammation. http://purl.obolibrary.org/obo/UBERON_0011574 mesonephric duct lumen http://purl.obolibrary.org/obo/UBERON_0005082 tube lumen A tube lumen that is part of a mesonephric duct. http://purl.obolibrary.org/obo/CL_4033184 dorsal root ganglion TRPV1 neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A sensory neuron that has the soma located in the dorsal root ganglion and expresses the marker transient receptor potential cation channel subfamily V member 1 (TRPV1). TRPV1 is the canonical heat and capsaicin nociceptor marker and is present in approximately 54% of TrkA-positive human DRG neurons. http://purl.obolibrary.org/obo/UBERON_0011582 paired limb/fin skeleton http://purl.obolibrary.org/obo/UBERON_0010912 subdivision of skeleton The collection of all skeletal elements in an individual limb or fin. http://purl.obolibrary.org/obo/CL_4079000 cervical dorsal root ganglion CGRP neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A peptidergic nociceptor whose soma is located in the cervical dorsal root ganglion, characterized by expression of calcitonin gene-related peptide (CGRP, encoded by CALCA). This small- to medium-diameter neuron belongs to the TrkA-positive peptidergic subpopulation and typically co-expresses substance P. It innervates peripheral tissues including skin and viscera, where it mediates neurogenic inflammation and nociceptive signalling through release of CGRP from peripheral terminals during tissue injury (Haberberger et al. 2019, PMID:31293388). In human DRG, CGRP-immunoreactive neurons represent a substantial proportion of nociceptors, comparable to the pattern observed in rodents (Rostock et al. 2018, PMID:29229553). http://purl.obolibrary.org/obo/UBERON_0011583 stylopodial skeleton http://purl.obolibrary.org/obo/UBERON_0010712 limb skeleton subdivision Proximal element of a free limb skeleton consisting of the femur and humerus in the forelimb stylopodium and hindlimb stylopodium respectively[VSAO, modified]. http://purl.obolibrary.org/obo/CL_4079001 cervical dorsal root ganglion endothelin-1 neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A sensory neuron whose soma is located in the cervical dorsal root ganglion and that expresses endothelin-1 (EDN1). In rat DRG, EDN1 immunoreactivity has been detected in a subset of neuron somata (Giaid et al. 1989, PMID:2678100). Endothelin-1 acts as an endogenous pain mediator, sensitizing nociceptors through activation of ETA and ETB receptors, and these neurons are implicated in vascular pain signalling. EDN1-expressing DRG neurons have been characterized in rat; their prevalence and properties in human DRG remain to be systematically determined, as EDN1 is not yet represented in human DRG single-cell transcriptomic datasets. http://purl.obolibrary.org/obo/UBERON_0011584 zeugopodial skeleton http://purl.obolibrary.org/obo/UBERON_0010712 limb skeleton subdivision Section of the forelimb skeleton located between the stylopodium and the autopodium. http://purl.obolibrary.org/obo/CL_4079002 cervical dorsal root ganglion Nav1.7 neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A nociceptor whose soma is located in the cervical dorsal root ganglion and that expresses the voltage-gated sodium channel Nav1.7 (encoded by SCN9A). This neuron is characterized by Nav1.7-dependent action potential initiation and amplification, which is essential for normal pain sensation in humans. Nav1.7 contributes approximately 50% of total sodium channel current in human DRG nociceptors (Chang et al. 2018, PMID:28424991). In human DRG, Nav1.7 immunoreactivity is detected in 54-57% of TrkA-positive neurons (Rostock et al. 2018, PMID:29229553). Human genetic evidence confirms Nav1.7 as necessary and sufficient for nociceptive function in these neurons. http://purl.obolibrary.org/obo/UBERON_0011585 cell condensation http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure Anatomical structure that is an aggregation of similar cells from which cartilages and bones form, and from which chondrogenesis and osteogenesis are initiated during repair and/or regeneration. (Hall and Miyake 1995). http://purl.obolibrary.org/obo/UBERON_0011587 pre-dentine http://purl.obolibrary.org/obo/UBERON_0010365 odontoid tissue Odontogenic tissue that is collagen-rich and characteristic of vertebrate teeth and tooth-like structures (e.g., odontodes) deposited by preodontoblasts and odontoblasts that are typically excluded from the matrix. http://purl.obolibrary.org/obo/CL_4079003 cervical dorsal root ganglion Nav1.9 neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A nociceptor whose soma is located in the cervical dorsal root ganglion and that expresses the voltage-gated sodium channel Nav1.9 (encoded by SCN11A). This neuron is characterized by a persistent, tetrodotoxin-resistant sodium current that modulates resting membrane potential and amplifies subthreshold depolarizations, contributing to enhanced excitability during inflammation (Dib-Hajj et al. 2002, PMID:11972962). In human DRG, Nav1.9-immunoreactive neurons constitute approximately 26% of TrkA-positive neurons, a significantly higher proportion than the 12% observed in mouse (Rostock et al. 2018, PMID:29229553), suggesting species differences in inflammatory pain processing. http://purl.obolibrary.org/obo/UBERON_0011588 pre-enamel http://purl.obolibrary.org/obo/UBERON_0010365 odontoid tissue Odontogenic tissue that is avascular non-mineralized matrix that is deposited by preameloblast and ameloblasts that are excluded from the matrix. http://purl.obolibrary.org/obo/CL_4079004 cervical dorsal root ganglion peripherin neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A small-diameter sensory neuron whose soma is located in the cervical dorsal root ganglion and that expresses peripherin (encoded by PRPH), a type III intermediate filament protein. This neuron is unmyelinated, conducts action potentials as a C-fiber, and encompasses nociceptive and thermoceptive functional subpopulations. In human DRG, peripherin-immunoreactive neurons are predominantly of small diameter (Chang et al. 2018, PMID:28424991), distinguishing them from large-diameter myelinated A-fiber neurons that instead express neurofilament heavy chain (Haberberger et al. 2019, PMID:31293388). In mice, peripherin similarly marks unmyelinated primary afferent neurons. http://purl.obolibrary.org/obo/UBERON_0011589 non-mineralized cartilage tissue http://purl.obolibrary.org/obo/UBERON_0002418 cartilage tissue Cartilage tissue that is not mineralized. http://purl.obolibrary.org/obo/CL_4079005 cervical dorsal root ganglion Piezo2 neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A mechanosensitive sensory neuron whose soma is located in the cervical dorsal root ganglion and that expresses the mechanically activated ion channel Piezo2 (encoded by PIEZO2). This neuron transduces mechanical stimuli and is involved in light touch perception and proprioception. In human DRG, Piezo2-immunoreactive neurons constitute approximately 35% of TrkA-positive neurons, compared to 26% in mouse (Rostock et al. 2018, PMID:29229553). This subpopulation includes both low-threshold mechanoreceptors mediating innocuous touch and a subset of mechanically sensitive nociceptors, reflecting the dual role of Piezo2 in somatosensation across species. http://purl.obolibrary.org/obo/UBERON_0011590 commissure of diencephalon http://purl.obolibrary.org/obo/UBERON_0011591 tract of diencephalon A commissure that is part of a diencephalon. http://purl.obolibrary.org/obo/CL_4079006 cervical dorsal root ganglion RET neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A non-peptidergic nociceptor whose soma is located in the cervical dorsal root ganglion and that expresses the receptor tyrosine kinase RET (encoded by RET). This neuron is distinguished from peptidergic nociceptors by its dependence on glial cell-derived neurotrophic factor family ligands rather than nerve growth factor, and in rodents it characteristically binds isolectin B4. In human DRG, RET-immunoreactive neurons constitute approximately 46% of TrkA-positive neurons, a significantly higher proportion than the 23% observed in mouse (Rostock et al. 2018, PMID:29229553), indicating an expanded non-peptidergic nociceptor compartment in humans. http://purl.obolibrary.org/obo/UBERON_0011591 tract of diencephalon http://purl.obolibrary.org/obo/UBERON_0007702 tract of brain An axon tract that is part of a diencephalon. http://purl.obolibrary.org/obo/UBERON_0011594 dentary tooth http://purl.obolibrary.org/obo/UBERON_0003268 tooth of lower jaw Tooth that is attached to a dentary/mandible[TAO,modified]. http://purl.obolibrary.org/obo/CL_4079007 cervical dorsal root ganglion substance P neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A peptidergic nociceptor whose soma is located in the cervical dorsal root ganglion and that expresses substance P, an 11-amino-acid neuropeptide cleaved from protachykinin-1 (encoded by TAC1). This small-diameter neuron frequently co-expresses CGRP and belongs to the TrkA-positive peptidergic population. Upon nociceptive activation, it releases substance P both centrally in the spinal cord dorsal horn and peripherally at sensory nerve terminals, mediating neurogenic inflammation through NK1 receptor signalling (Haberberger et al. 2019, PMID:31293388). Substance P-immunoreactive neurons have been consistently identified in human DRG by immunohistochemistry across multiple studies. http://purl.obolibrary.org/obo/UBERON_0011595 jaw region http://purl.obolibrary.org/obo/UBERON_0010314 structure with developmental contribution from neural crest A subdivision of the head that corresponds to the jaw skeleton, containing both soft tissue, skeleton and teeth (when present). The jaw region is divided into upper and lower regions. http://purl.obolibrary.org/obo/UBERON_0011597 bone of upper jaw http://purl.obolibrary.org/obo/UBERON_0012360 bone of jaw Any bone that is part of the upper jaw skeleton. This includes (when present): the maxilla, the quadrate (in some species). http://purl.obolibrary.org/obo/CL_4079008 cervical dorsal root ganglion TRPV1 neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A polymodal nociceptor whose soma is located in the cervical dorsal root ganglion and that expresses the transient receptor potential vanilloid 1 channel (TRPV1, encoded by TRPV1). This neuron detects noxious heat above 43 degrees Celsius, protons, and endogenous lipid mediators, and is activated by capsaicin. In human DRG, TRPV1-immunoreactive neurons constitute approximately 54% of TrkA-positive neurons, significantly higher than the 35% observed in mouse (Rostock et al. 2018, PMID:29229553). These neurons are predominantly small-diameter nociceptors that innervate skin and visceral organs, where they function as primary detectors of thermal and chemical noxious stimuli. http://purl.obolibrary.org/obo/UBERON_0011601 gingiva of upper jaw http://purl.obolibrary.org/obo/UBERON_0001828 gingiva A gingiva that is part of a upper jaw region. http://purl.obolibrary.org/obo/UBERON_0011602 gingiva of lower jaw http://purl.obolibrary.org/obo/UBERON_0001828 gingiva A gingiva that is part of a lower jaw region. http://purl.obolibrary.org/obo/UBERON_0011642 oral epithelium from ectoderm http://purl.obolibrary.org/obo/UBERON_0010371 ecto-epithelium An epithelium that develops_from a ectoderm and is part of a oral epithelium. http://purl.obolibrary.org/obo/CL_4079010 intrinsic cardiac ganglion TH neuron http://purl.obolibrary.org/obo/CL_0000107 autonomic neuron A catecholaminergic neuron whose soma is located in an intrinsic cardiac ganglion and that expresses tyrosine hydroxylase (TH, encoded by TH), the rate-limiting enzyme in catecholamine biosynthesis. This neuron constitutes a minor subpopulation within the predominantly cholinergic parasympathetic intrinsic cardiac nervous system, identified in adult human cardiac ganglia by immunohistochemistry (Singh et al. 1999, PMID:9918529; Kawano et al. 2003, DOI:10.1007/s003800300005). It participates in local cardiac autonomic regulation, including modulation of heart rate and contractility. Its catecholaminergic phenotype distinguishes it from the majority cholinergic neurons of the same ganglia. http://purl.obolibrary.org/obo/UBERON_0011645 iliofemoralis muscle http://purl.obolibrary.org/obo/UBERON_0001325 muscle of pelvis Limb extensor that runs from ilium to femur. http://purl.obolibrary.org/obo/CL_4079011 lumbar dorsal root ganglion CGRP neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A peptidergic nociceptor whose soma is located in the lumbar dorsal root ganglion, characterized by expression of calcitonin gene-related peptide (CGRP, encoded by CALCA). This small- to medium-diameter neuron belongs to the TrkA-positive peptidergic subpopulation and typically co-expresses substance P. It innervates peripheral tissues including skin and viscera, where it mediates neurogenic inflammation and nociceptive signalling through release of CGRP from peripheral terminals during tissue injury (Haberberger et al. 2019, PMID:31293388). In human DRG, CGRP-immunoreactive neurons represent a substantial proportion of nociceptors, comparable to the pattern observed in rodents (Rostock et al. 2018, PMID:29229553). http://purl.obolibrary.org/obo/UBERON_0011676 subdivision of organism along main body axis http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision A major subdivision of an organism that divides an organism along its main body axis (typically anterio-posterior axis). In vertebrates, this is based on the vertebral column. http://purl.obolibrary.org/obo/CL_4079012 lumbar dorsal root ganglion endothelin-1 neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A sensory neuron whose soma is located in the lumbar dorsal root ganglion and that expresses endothelin-1 (EDN1). In rat DRG, EDN1 immunoreactivity has been detected in a subset of neuron somata (Giaid et al. 1989, PMID:2678100). Endothelin-1 acts as an endogenous pain mediator, sensitizing nociceptors through activation of ETA and ETB receptors, and these neurons are implicated in vascular pain signalling. EDN1-expressing DRG neurons have been characterized in rat; their prevalence and properties in human DRG remain to be systematically determined, as EDN1 is not yet represented in human DRG single-cell transcriptomic datasets. http://purl.obolibrary.org/obo/UBERON_0011677 trunk vertebra http://purl.obolibrary.org/obo/UBERON_0004451 trunk or cervical vertebra A vertebra in the trunk region. For tetrapods, includes lumbar and thoracic vertebrae. Excludes caudal/coccygeal vertebra, which are located posteriorly. In tetrapods this includes thoracic, lumbar and sacral vertebrae, and excludes the cervical vertebrae, which are located anteriorly. http://purl.obolibrary.org/obo/CL_4079013 lumbar dorsal root ganglion Nav1.7 neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A nociceptor whose soma is located in the lumbar dorsal root ganglion and that expresses the voltage-gated sodium channel Nav1.7 (encoded by SCN9A). This neuron is characterized by Nav1.7-dependent action potential initiation and amplification, which is essential for normal pain sensation in humans. Nav1.7 contributes approximately 50% of total sodium channel current in human DRG nociceptors (Chang et al. 2018, PMID:28424991). In human DRG, Nav1.7 immunoreactivity is detected in 54-57% of TrkA-positive neurons (Rostock et al. 2018, PMID:29229553). Human genetic evidence confirms Nav1.7 as necessary and sufficient for nociceptive function in these neurons. http://purl.obolibrary.org/obo/UBERON_0011679 proximal tarsal bone http://purl.obolibrary.org/obo/UBERON_0015081 proximal tarsal endochondral element A tarsal bone that connected_to a hindlimb zeugopod skeleton. http://purl.obolibrary.org/obo/CL_4079014 lumbar dorsal root ganglion Nav1.9 neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A nociceptor whose soma is located in the lumbar dorsal root ganglion and that expresses the voltage-gated sodium channel Nav1.9 (encoded by SCN11A). This neuron is characterized by a persistent, tetrodotoxin-resistant sodium current that modulates resting membrane potential and amplifies subthreshold depolarizations, contributing to enhanced excitability during inflammation (Dib-Hajj et al. 2002, PMID:11972962). In human DRG, Nav1.9-immunoreactive neurons constitute approximately 26% of TrkA-positive neurons, a significantly higher proportion than the 12% observed in mouse (Rostock et al. 2018, PMID:29229553), suggesting species differences in inflammatory pain processing. http://purl.obolibrary.org/obo/UBERON_0011695 embryonic cardiovascular system http://purl.obolibrary.org/obo/UBERON_0004535 cardiovascular system A cardiovascular system that is part of a conceptus. http://purl.obolibrary.org/obo/CL_4079015 lumbar dorsal root ganglion peripherin neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A small-diameter sensory neuron whose soma is located in the lumbar dorsal root ganglion and that expresses peripherin (encoded by PRPH), a type III intermediate filament protein. This neuron is unmyelinated, conducts action potentials as a C-fiber, and encompasses nociceptive and thermoceptive functional subpopulations. In human DRG, peripherin-immunoreactive neurons are predominantly of small diameter (Chang et al. 2018, PMID:28424991), distinguishing them from large-diameter myelinated A-fiber neurons that instead express neurofilament heavy chain (Haberberger et al. 2019, PMID:31293388). In mice, peripherin similarly marks unmyelinated primary afferent neurons. http://purl.obolibrary.org/obo/UBERON_0011769 cartilaginous projection http://purl.obolibrary.org/obo/UBERON_0004529 anatomical projection Anatomical projection that is composed of cartilage tissue. http://purl.obolibrary.org/obo/CL_4079016 lumbar dorsal root ganglion Piezo2 neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A mechanosensitive sensory neuron whose soma is located in the lumbar dorsal root ganglion and that expresses the mechanically activated ion channel Piezo2 (encoded by PIEZO2). This neuron transduces mechanical stimuli and is involved in light touch perception and proprioception. In human DRG, Piezo2-immunoreactive neurons constitute approximately 35% of TrkA-positive neurons, compared to 26% in mouse (Rostock et al. 2018, PMID:29229553). This subpopulation includes both low-threshold mechanoreceptors mediating innocuous touch and a subset of mechanically sensitive nociceptors, reflecting the dual role of Piezo2 in somatosensation across species. http://purl.obolibrary.org/obo/UBERON_0011772 lower jaw opening http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space An anatomical space that is part of a bone of lower jaw. http://purl.obolibrary.org/obo/CL_4079017 lumbar dorsal root ganglion RET neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A non-peptidergic nociceptor whose soma is located in the lumbar dorsal root ganglion and that expresses the receptor tyrosine kinase RET (encoded by RET). This neuron is distinguished from peptidergic nociceptors by its dependence on glial cell-derived neurotrophic factor family ligands rather than nerve growth factor, and in rodents it characteristically binds isolectin B4. In human DRG, RET-immunoreactive neurons constitute approximately 46% of TrkA-positive neurons, a significantly higher proportion than the 23% observed in mouse (Rostock et al. 2018, PMID:29229553), indicating an expanded non-peptidergic nociceptor compartment in humans. http://purl.obolibrary.org/obo/UBERON_0011773 upper jaw opening http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space An anatomical space that is part of a bone of upper jaw. http://purl.obolibrary.org/obo/UBERON_0011775 vagus nerve nucleus http://purl.obolibrary.org/obo/UBERON_0009662 hindbrain nucleus A cranial nerve nucleus that is associated with a vagus nerve. http://purl.obolibrary.org/obo/CL_4079018 lumbar dorsal root ganglion substance P neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A peptidergic nociceptor whose soma is located in the lumbar dorsal root ganglion and that expresses substance P, an 11-amino-acid neuropeptide cleaved from protachykinin-1 (encoded by TAC1). This small-diameter neuron frequently co-expresses CGRP and belongs to the TrkA-positive peptidergic population. Upon nociceptive activation, it releases substance P both centrally in the spinal cord dorsal horn and peripherally at sensory nerve terminals, mediating neurogenic inflammation through NK1 receptor signalling (Haberberger et al. 2019, PMID:31293388). Substance P-immunoreactive neurons have been consistently identified in human DRG by immunohistochemistry across multiple studies. http://purl.obolibrary.org/obo/UBERON_0011777 nucleus of spinal cord http://purl.obolibrary.org/obo/UBERON_0000125 neural nucleus A neural nucleus that is part of the spinal cord. http://purl.obolibrary.org/obo/CL_4079019 lumbar dorsal root ganglion TRPV1 neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A polymodal nociceptor whose soma is located in the lumbar dorsal root ganglion and that expresses the transient receptor potential vanilloid 1 channel (TRPV1, encoded by TRPV1). This neuron detects noxious heat above 43 degrees Celsius, protons, and endogenous lipid mediators, and is activated by capsaicin. In human DRG, TRPV1-immunoreactive neurons constitute approximately 54% of TrkA-positive neurons, significantly higher than the 35% observed in mouse (Rostock et al. 2018, PMID:29229553). These neurons are predominantly small-diameter nociceptors that innervate skin and visceral organs, where they function as primary detectors of thermal and chemical noxious stimuli. http://purl.obolibrary.org/obo/UBERON_0011779 nerve of head region http://purl.obolibrary.org/obo/UBERON_0001021 nerve A nerve that is part of a head. http://purl.obolibrary.org/obo/CL_4079020 sacral dorsal root ganglion CGRP neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A peptidergic nociceptor whose soma is located in the sacral dorsal root ganglion, characterized by expression of calcitonin gene-related peptide (CGRP, encoded by CALCA). This small- to medium-diameter neuron belongs to the TrkA-positive peptidergic subpopulation and typically co-expresses substance P. It innervates peripheral tissues including skin and viscera, where it mediates neurogenic inflammation and nociceptive signalling through release of CGRP from peripheral terminals during tissue injury (Haberberger et al. 2019, PMID:31293388). In human DRG, CGRP-immunoreactive neurons represent a substantial proportion of nociceptors, comparable to the pattern observed in rodents (Rostock et al. 2018, PMID:29229553). http://purl.obolibrary.org/obo/UBERON_0011814 non-neurogenic ectodermal placode http://purl.obolibrary.org/obo/UBERON_0005085 ectodermal placode Ectodermal placode that does not develop into a component of the nervous system. http://purl.obolibrary.org/obo/CL_4079021 sacral dorsal root ganglion endothelin-1 neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A sensory neuron whose soma is located in the sacral dorsal root ganglion and that expresses endothelin-1 (EDN1). In rat DRG, EDN1 immunoreactivity has been detected in a subset of neuron somata (Giaid et al. 1989, PMID:2678100). Endothelin-1 acts as an endogenous pain mediator, sensitizing nociceptors through activation of ETA and ETB receptors, and these neurons are implicated in vascular pain signalling. EDN1-expressing DRG neurons have been characterized in rat; their prevalence and properties in human DRG remain to be systematically determined, as EDN1 is not yet represented in human DRG single-cell transcriptomic datasets. http://purl.obolibrary.org/obo/UBERON_0011817 skin appendage placode http://purl.obolibrary.org/obo/UBERON_0011814 non-neurogenic ectodermal placode An ectodermal placode that gives rise to any of the cutaneous appendages that protrude from the skin epidermis (heair, feathers, epidermal scales). http://purl.obolibrary.org/obo/CL_4079022 sacral dorsal root ganglion Nav1.7 neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A nociceptor whose soma is located in the sacral dorsal root ganglion and that expresses the voltage-gated sodium channel Nav1.7 (encoded by SCN9A). This neuron is characterized by Nav1.7-dependent action potential initiation and amplification, which is essential for normal pain sensation in humans. Nav1.7 contributes approximately 50% of total sodium channel current in human DRG nociceptors (Chang et al. 2018, PMID:28424991). In human DRG, Nav1.7 immunoreactivity is detected in 54-57% of TrkA-positive neurons (Rostock et al. 2018, PMID:29229553). Human genetic evidence confirms Nav1.7 as necessary and sufficient for nociceptive function in these neurons. http://purl.obolibrary.org/obo/UBERON_0011820 atrioventricular region http://purl.obolibrary.org/obo/UBERON_0007651 anatomical junction An anatomical junction that divides and overlaps with and atrium and a ventricle in the heart. http://purl.obolibrary.org/obo/CL_4079023 sacral dorsal root ganglion Nav1.9 neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A nociceptor whose soma is located in the sacral dorsal root ganglion and that expresses the voltage-gated sodium channel Nav1.9 (encoded by SCN11A). This neuron is characterized by a persistent, tetrodotoxin-resistant sodium current that modulates resting membrane potential and amplifies subthreshold depolarizations, contributing to enhanced excitability during inflammation (Dib-Hajj et al. 2002, PMID:11972962). In human DRG, Nav1.9-immunoreactive neurons constitute approximately 26% of TrkA-positive neurons, a significantly higher proportion than the 12% observed in mouse (Rostock et al. 2018, PMID:29229553), suggesting species differences in inflammatory pain processing. http://purl.obolibrary.org/obo/UBERON_0011821 irregular connective tissue http://purl.obolibrary.org/obo/UBERON_0002384 connective tissue Connective tissue, which consists of a population of connective tissue cells, the intercellular matrix of which contains an irregular network of collagen and elastic fiber bundles. Examples: areolar tissue, mucoid tissue, connective tissue of peritoneum, connective tissue of fibrous pericardium. http://purl.obolibrary.org/obo/CL_4079024 sacral dorsal root ganglion peripherin neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A small-diameter sensory neuron whose soma is located in the sacral dorsal root ganglion and that expresses peripherin (encoded by PRPH), a type III intermediate filament protein. This neuron is unmyelinated, conducts action potentials as a C-fiber, and encompasses nociceptive and thermoceptive functional subpopulations. In human DRG, peripherin-immunoreactive neurons are predominantly of small diameter (Chang et al. 2018, PMID:28424991), distinguishing them from large-diameter myelinated A-fiber neurons that instead express neurofilament heavy chain (Haberberger et al. 2019, PMID:31293388). In mice, peripherin similarly marks unmyelinated primary afferent neurons. http://purl.obolibrary.org/obo/UBERON_0011822 dense irregular connective tissue http://purl.obolibrary.org/obo/UBERON_0011823 dense connective tissue Irregular connective tissue is an irregular connective tissue, the intercellular matrix of which contains a dense irregular network of collagen and elastic fiber bundles. Examples: connective tissue of peritoneum, connective tissue of fibrous pericardium. http://purl.obolibrary.org/obo/CL_4079025 sacral dorsal root ganglion Piezo2 neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A mechanosensitive sensory neuron whose soma is located in the sacral dorsal root ganglion and that expresses the mechanically activated ion channel Piezo2 (encoded by PIEZO2). This neuron transduces mechanical stimuli and is involved in light touch perception and proprioception. In human DRG, Piezo2-immunoreactive neurons constitute approximately 35% of TrkA-positive neurons, compared to 26% in mouse (Rostock et al. 2018, PMID:29229553). This subpopulation includes both low-threshold mechanoreceptors mediating innocuous touch and a subset of mechanically sensitive nociceptors, reflecting the dual role of Piezo2 in somatosensation across species. http://purl.obolibrary.org/obo/UBERON_0011823 dense connective tissue http://purl.obolibrary.org/obo/UBERON_0002384 connective tissue Dense connective tissue is mainly composed of collagen type I. Crowded between the collagen fibers are rows of fibroblasts, fiber-forming cells, that manufacture the fibers. Dense connective tissue forms strong, rope-like structures such as tendons and ligaments. Tendons attach skeletal muscles to bones; ligaments connect bones to bones at joints. Ligaments are more stretchy and contain more elastic fibers than tendons. Dense connective tissue also make up the lower layers of the skin (dermis), where it is arranged in sheets. http://purl.obolibrary.org/obo/CL_4079026 sacral dorsal root ganglion RET neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A non-peptidergic nociceptor whose soma is located in the sacral dorsal root ganglion and that expresses the receptor tyrosine kinase RET (encoded by RET). This neuron is distinguished from peptidergic nociceptors by its dependence on glial cell-derived neurotrophic factor family ligands rather than nerve growth factor, and in rodents it characteristically binds isolectin B4. In human DRG, RET-immunoreactive neurons constitute approximately 46% of TrkA-positive neurons, a significantly higher proportion than the 23% observed in mouse (Rostock et al. 2018, PMID:29229553), indicating an expanded non-peptidergic nociceptor compartment in humans. http://purl.obolibrary.org/obo/UBERON_0011825 loose connective tissue http://purl.obolibrary.org/obo/UBERON_0011821 irregular connective tissue Irregular connective tissue, the intercellular matrix of which contains a sparse irregular network of collagen and elastic fiber bundles. Examples: areolar tissue, neuroglial tissue, mucoid tissue. http://purl.obolibrary.org/obo/CL_4079027 sacral dorsal root ganglion substance P neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A peptidergic nociceptor whose soma is located in the sacral dorsal root ganglion and that expresses substance P, an 11-amino-acid neuropeptide cleaved from protachykinin-1 (encoded by TAC1). This small-diameter neuron frequently co-expresses CGRP and belongs to the TrkA-positive peptidergic population. Upon nociceptive activation, it releases substance P both centrally in the spinal cord dorsal horn and peripherally at sensory nerve terminals, mediating neurogenic inflammation through NK1 receptor signalling (Haberberger et al. 2019, PMID:31293388). Substance P-immunoreactive neurons have been consistently identified in human DRG by immunohistochemistry across multiple studies. http://purl.obolibrary.org/obo/UBERON_0011845 duct of sebaceous gland http://purl.obolibrary.org/obo/UBERON_0000058 duct A duct that is part of a sebaceous gland. http://purl.obolibrary.org/obo/CL_4079028 sacral dorsal root ganglion TRPV1 neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A polymodal nociceptor whose soma is located in the sacral dorsal root ganglion and that expresses the transient receptor potential vanilloid 1 channel (TRPV1, encoded by TRPV1). This neuron detects noxious heat above 43 degrees Celsius, protons, and endogenous lipid mediators, and is activated by capsaicin. In human DRG, TRPV1-immunoreactive neurons constitute approximately 54% of TrkA-positive neurons, significantly higher than the 35% observed in mouse (Rostock et al. 2018, PMID:29229553). These neurons are predominantly small-diameter nociceptors that innervate skin and visceral organs, where they function as primary detectors of thermal and chemical noxious stimuli. http://purl.obolibrary.org/obo/UBERON_0011846 acinus of sebaceous gland http://purl.obolibrary.org/obo/UBERON_0011858 acinus of exocrine gland An acinus that is part of a sebaceous gland. http://purl.obolibrary.org/obo/UBERON_0011847 acinus of parotid gland http://purl.obolibrary.org/obo/UBERON_0013232 serous acinus An acinus that is part of a parotid gland. http://purl.obolibrary.org/obo/UBERON_0011850 acinus of salivary gland http://purl.obolibrary.org/obo/UBERON_0011858 acinus of exocrine gland An acinus that is part of a salivary gland. http://purl.obolibrary.org/obo/UBERON_0011856 acinus of lactiferous gland http://purl.obolibrary.org/obo/UBERON_0011858 acinus of exocrine gland An acinus that is part of a mammary gland. http://purl.obolibrary.org/obo/UBERON_0011857 acinus of lacrimal gland http://purl.obolibrary.org/obo/UBERON_0011858 acinus of exocrine gland An acinus that is part of a lacrimal gland. http://purl.obolibrary.org/obo/UBERON_0011858 acinus of exocrine gland http://purl.obolibrary.org/obo/UBERON_0009842 glandular acinus An acinus that is part of a exocrine gland. http://purl.obolibrary.org/obo/UBERON_0011861 aorta collagen fibril http://purl.obolibrary.org/obo/UBERON_0011860 collection of collagen fibrils The connective tissue bundles in the extracellular matrix of aorta tissue that are composed of collagen, and play a role in tissue strength and elasticity. http://purl.obolibrary.org/obo/UBERON_0011862 pulmonary collagen fibril http://purl.obolibrary.org/obo/UBERON_0011860 collection of collagen fibrils The connective tissue bundles in the extracellular matrix of pulmonary tissue that are composed of collagen, and play a role in tissue strength and elasticity. http://purl.obolibrary.org/obo/UBERON_0011863 bone collagen fibril http://purl.obolibrary.org/obo/UBERON_0011860 collection of collagen fibrils The connective tissue bundles in the extracellular matrix of bone tissue that are composed of collagen, and play a role in tissue strength and elasticity. http://purl.obolibrary.org/obo/CL_4079029 thoracic dorsal root ganglion CGRP neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A peptidergic nociceptor whose soma is located in the thoracic dorsal root ganglion, characterized by expression of calcitonin gene-related peptide (CGRP, encoded by CALCA). This small- to medium-diameter neuron belongs to the TrkA-positive peptidergic subpopulation and typically co-expresses substance P. It innervates peripheral tissues including skin and viscera, where it mediates neurogenic inflammation and nociceptive signalling through release of CGRP from peripheral terminals during tissue injury (Haberberger et al. 2019, PMID:31293388). In human DRG, CGRP-immunoreactive neurons represent a substantial proportion of nociceptors, comparable to the pattern observed in rodents (Rostock et al. 2018, PMID:29229553). http://purl.obolibrary.org/obo/UBERON_0011864 tendon collagen fibril http://purl.obolibrary.org/obo/UBERON_0011860 collection of collagen fibrils The connective tissue bundles in the extracellular matrix of tendon tissue that are composed of collagen, and play a role in tissue strength and elasticity. http://purl.obolibrary.org/obo/UBERON_0011865 corneal stroma collagen fibril http://purl.obolibrary.org/obo/UBERON_0011860 collection of collagen fibrils The connective tissue bundles in the extracellular matrix of corneal stroma that are composed of collagen, and play a role in tissue strength and elasticity. http://purl.obolibrary.org/obo/CL_4079030 thoracic dorsal root ganglion endothelin-1 neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A sensory neuron whose soma is located in the thoracic dorsal root ganglion and that expresses endothelin-1 (EDN1). In rat DRG, EDN1 immunoreactivity has been detected in a subset of neuron somata (Giaid et al. 1989, PMID:2678100). Endothelin-1 acts as an endogenous pain mediator, sensitizing nociceptors through activation of ETA and ETB receptors, and these neurons are implicated in vascular pain signalling. EDN1-expressing DRG neurons have been characterized in rat; their prevalence and properties in human DRG remain to be systematically determined, as EDN1 is not yet represented in human DRG single-cell transcriptomic datasets. http://purl.obolibrary.org/obo/UBERON_0011875 ligament of sternoclavicular joint http://purl.obolibrary.org/obo/UBERON_0008846 skeletal ligament A skeletal ligament that is part of a sternoclavicular joint. http://purl.obolibrary.org/obo/UBERON_0011878 muscle layer of esophagus http://purl.obolibrary.org/obo/UBERON_0018261 muscular coat of digestive tract A muscle layer that is part of a wall of esophagus. http://purl.obolibrary.org/obo/UBERON_0011892 anterior uvea http://purl.obolibrary.org/obo/UBERON_0010314 structure with developmental contribution from neural crest Front (ventral) portion of the vascular, pigmentary, or middle coat of the eye, including the ciliary body and the iris. http://purl.obolibrary.org/obo/CL_4079031 thoracic dorsal root ganglion Nav1.7 neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A nociceptor whose soma is located in the thoracic dorsal root ganglion and that expresses the voltage-gated sodium channel Nav1.7 (encoded by SCN9A). This neuron is characterized by Nav1.7-dependent action potential initiation and amplification, which is essential for normal pain sensation in humans. Nav1.7 contributes approximately 50% of total sodium channel current in human DRG nociceptors (Chang et al. 2018, PMID:28424991). In human DRG, Nav1.7 immunoreactivity is detected in 54-57% of TrkA-positive neurons (Rostock et al. 2018, PMID:29229553). Human genetic evidence confirms Nav1.7 as necessary and sufficient for nociceptive function in these neurons. http://purl.obolibrary.org/obo/UBERON_0011894 lumen of vagina http://purl.obolibrary.org/obo/UBERON_0002558 organ cavity An organ cavity that is part of a vagina. http://purl.obolibrary.org/obo/UBERON_0011899 epimysium http://purl.obolibrary.org/obo/UBERON_0011822 dense irregular connective tissue Epimysium is a layer of connective tissue which ensheaths the entire muscle. It is composed of dense irregular connective tissue. It is continuous with fascia and other connective tissue wrappings of muscle including the endomysium, and perimysium. It is also continuous with tendons where it becomes thicker and collagenous. http://purl.obolibrary.org/obo/CL_4079032 thoracic dorsal root ganglion Nav1.9 neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A nociceptor whose soma is located in the thoracic dorsal root ganglion and that expresses the voltage-gated sodium channel Nav1.9 (encoded by SCN11A). This neuron is characterized by a persistent, tetrodotoxin-resistant sodium current that modulates resting membrane potential and amplifies subthreshold depolarizations, contributing to enhanced excitability during inflammation (Dib-Hajj et al. 2002, PMID:11972962). In human DRG, Nav1.9-immunoreactive neurons constitute approximately 26% of TrkA-positive neurons, a significantly higher proportion than the 12% observed in mouse (Rostock et al. 2018, PMID:29229553), suggesting species differences in inflammatory pain processing. http://purl.obolibrary.org/obo/UBERON_0011919 yolk sac blood island http://purl.obolibrary.org/obo/UBERON_0003061 blood island Masses of developing blood cells attached to endothelium in the yolk sac. http://purl.obolibrary.org/obo/UBERON_0011922 cochlear basement membrane http://purl.obolibrary.org/obo/UBERON_0005769 basement membrane of epithelium The the continuous basement membrane found within the membranous labyrinth of the cochlea, known to extend from the limbus, down to the inner sulcus, across the basilar membrane, up to the external sulcus to the spiral prominence and radiating into the spiral ligament ensheathing the root cell processes. http://purl.obolibrary.org/obo/CL_4079033 thoracic dorsal root ganglion peripherin neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A small-diameter sensory neuron whose soma is located in the thoracic dorsal root ganglion and that expresses peripherin (encoded by PRPH), a type III intermediate filament protein. This neuron is unmyelinated, conducts action potentials as a C-fiber, and encompasses nociceptive and thermoceptive functional subpopulations. In human DRG, peripherin-immunoreactive neurons are predominantly of small diameter (Chang et al. 2018, PMID:28424991), distinguishing them from large-diameter myelinated A-fiber neurons that instead express neurofilament heavy chain (Haberberger et al. 2019, PMID:31293388). In mice, peripherin similarly marks unmyelinated primary afferent neurons. http://purl.obolibrary.org/obo/UBERON_0011925 preganglionic autonomic fiber http://purl.obolibrary.org/obo/UBERON_0003041 trigeminal nerve fibers Nerve fibers which project from the central nervous system to autonomic ganglia. In the sympathetic division most preganglionic fibers originate with neurons in the intermediolateral column of the spinal cord, exit via ventral roots from upper thoracic through lower lumbar segments, and project to the paravertebral ganglia; there they either terminate in synapses or continue through the splanchnic nerves to the prevertebral ganglia. In the parasympathetic division the fibers originate in neurons of the brain stem and sacral spinal cord. In both divisions the principal transmitter is acetylcholine but peptide cotransmitters may also be released. http://purl.obolibrary.org/obo/UBERON_0011927 preganglionic sympathetic fiber http://purl.obolibrary.org/obo/UBERON_0011925 preganglionic autonomic fiber A cholinergic axonal fiber projecting from the CNS to a sympathetic ganglion. http://purl.obolibrary.org/obo/CL_4079034 thoracic dorsal root ganglion Piezo2 neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A mechanosensitive sensory neuron whose soma is located in the thoracic dorsal root ganglion and that expresses the mechanically activated ion channel Piezo2 (encoded by PIEZO2). This neuron transduces mechanical stimuli and is involved in light touch perception and proprioception. In human DRG, Piezo2-immunoreactive neurons constitute approximately 35% of TrkA-positive neurons, compared to 26% in mouse (Rostock et al. 2018, PMID:29229553). This subpopulation includes both low-threshold mechanoreceptors mediating innocuous touch and a subset of mechanically sensitive nociceptors, reflecting the dual role of Piezo2 in somatosensation across species. http://purl.obolibrary.org/obo/UBERON_0011930 preganglionic parasympathetic fiber http://purl.obolibrary.org/obo/UBERON_0011925 preganglionic autonomic fiber A cholinergic axonal fibers projecting from the CNS to a parasympathetic ganglion. http://purl.obolibrary.org/obo/UBERON_0011931 nasal hair http://purl.obolibrary.org/obo/UBERON_0010171 strand of hair of face Hair in the nose. http://purl.obolibrary.org/obo/CL_4079035 thoracic dorsal root ganglion RET neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A non-peptidergic nociceptor whose soma is located in the thoracic dorsal root ganglion and that expresses the receptor tyrosine kinase RET (encoded by RET). This neuron is distinguished from peptidergic nociceptors by its dependence on glial cell-derived neurotrophic factor family ligands rather than nerve growth factor, and in rodents it characteristically binds isolectin B4. In human DRG, RET-immunoreactive neurons constitute approximately 46% of TrkA-positive neurons, a significantly higher proportion than the 23% observed in mouse (Rostock et al. 2018, PMID:29229553), indicating an expanded non-peptidergic nociceptor compartment in humans. http://purl.obolibrary.org/obo/UBERON_0011932 pilosebaceous unit http://purl.obolibrary.org/obo/UBERON_0000063 organ subunit An epidermal invagination that has as parts a hair follicle, a sebaceous gland, and arrector pili muscle. http://purl.obolibrary.org/obo/UBERON_0011947 ureter luminal urothelium http://purl.obolibrary.org/obo/UBERON_0011945 luminal layer of epithelium A luminal layer of epithelium that is part of a ureter. http://purl.obolibrary.org/obo/CL_4079036 thoracic dorsal root ganglion substance P neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A peptidergic nociceptor whose soma is located in the thoracic dorsal root ganglion and that expresses substance P, an 11-amino-acid neuropeptide cleaved from protachykinin-1 (encoded by TAC1). This small-diameter neuron frequently co-expresses CGRP and belongs to the TrkA-positive peptidergic population. Upon nociceptive activation, it releases substance P both centrally in the spinal cord dorsal horn and peripherally at sensory nerve terminals, mediating neurogenic inflammation through NK1 receptor signalling (Haberberger et al. 2019, PMID:31293388). Substance P-immunoreactive neurons have been consistently identified in human DRG by immunohistochemistry across multiple studies. http://purl.obolibrary.org/obo/UBERON_0011949 endometrium luminal epithelium http://purl.obolibrary.org/obo/UBERON_0011945 luminal layer of epithelium A luminal layer of epithelium that is part of a endometrium epithelium. http://purl.obolibrary.org/obo/UBERON_0011950 mammary gland luminal epithelium http://purl.obolibrary.org/obo/UBERON_0011945 luminal layer of epithelium The inner cell layer of the mammary epithelium bilayer that lines the luminal surface of mammary gland ducts and alveoli; luminal cells have only limited contact with the underlying basement membrane and surrounding connective tissue; they are secretory epithelial cells characterized by the expression of the receptors for systemic hormones, i.e. estrogens, progesterone and prolactin. http://purl.obolibrary.org/obo/CL_4079037 thoracic dorsal root ganglion TRPV1 neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A polymodal nociceptor whose soma is located in the thoracic dorsal root ganglion and that expresses the transient receptor potential vanilloid 1 channel (TRPV1, encoded by TRPV1). This neuron detects noxious heat above 43 degrees Celsius, protons, and endogenous lipid mediators, and is activated by capsaicin. In human DRG, TRPV1-immunoreactive neurons constitute approximately 54% of TrkA-positive neurons, significantly higher than the 35% observed in mouse (Rostock et al. 2018, PMID:29229553). These neurons are predominantly small-diameter nociceptors that innervate skin and visceral organs, where they function as primary detectors of thermal and chemical noxious stimuli. http://purl.obolibrary.org/obo/UBERON_0011951 prostate luminal epithelium http://purl.obolibrary.org/obo/UBERON_0011945 luminal layer of epithelium A luminal layer of epithelium that is part of a prostate gland. http://purl.obolibrary.org/obo/UBERON_0011953 stomach glandular region http://purl.obolibrary.org/obo/UBERON_0009870 zone of stomach A region of the stomach that is lined with glandular epithelium. http://purl.obolibrary.org/obo/UBERON_0035005 preputial swelling of male http://purl.obolibrary.org/obo/UBERON_0035004 preputial swelling http://purl.obolibrary.org/obo/UBERON_0011955 left hepatic vein http://purl.obolibrary.org/obo/UBERON_0001143 hepatic vein A hepatic vein that is part of a left lobe of liver. http://purl.obolibrary.org/obo/UBERON_0011956 right hepatic vein http://purl.obolibrary.org/obo/UBERON_0001143 hepatic vein A hepatic vein that is part of a right lobe of liver. http://purl.obolibrary.org/obo/NCBITaxon_55879 Rhabditoidea http://purl.obolibrary.org/obo/NCBITaxon_2301119 Rhabditomorpha http://purl.obolibrary.org/obo/UBERON_0011960 articular capsule of glenohumeral joint http://purl.obolibrary.org/obo/UBERON_0001484 articular capsule An articular capsule that is part of the glenohumeral joint. http://purl.obolibrary.org/obo/UBERON_0011965 saddle joint http://purl.obolibrary.org/obo/UBERON_0000982 skeletal joint In a saddle joint (sellar joint, articulation by reciprocal reception) the opposing surfaces are reciprocally concave-convex. https://purl.brain-bican.org/ontology/mbao/MBA_1000 extrapyramidal fiber systems https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions http://purl.obolibrary.org/obo/UBERON_0011972 medial ligament of ankle joint http://purl.obolibrary.org/obo/UBERON_0008846 skeletal ligament A skeletal ligament that connects a tibia and connects a tarsal skeleton. http://purl.obolibrary.org/obo/UBERON_0011973 epiphysis of phalanx of pes http://purl.obolibrary.org/obo/UBERON_0001437 epiphysis An epiphysis that is part of a phalanx of a pes [Automatically generated definition]. https://purl.brain-bican.org/ontology/mbao/MBA_796 Dopaminergic A13 group https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions http://purl.obolibrary.org/obo/UBERON_0011974 epiphysis of proximal phalanx of pes http://purl.obolibrary.org/obo/UBERON_0011973 epiphysis of phalanx of pes An epiphysis that is part of a proximal phalanx of pes. http://purl.obolibrary.org/obo/UBERON_0011975 epiphysis of middle phalanx of pes http://purl.obolibrary.org/obo/UBERON_0011973 epiphysis of phalanx of pes An epiphysis that is part of a middle phalanx of pes. https://purl.brain-bican.org/ontology/mbao/MBA_117 optic chiasm https://purl.brain-bican.org/ontology/mbao/MBA_1009 fiber tracts http://purl.obolibrary.org/obo/UBERON_0011976 epiphysis of distal phalanx of pes http://purl.obolibrary.org/obo/UBERON_0011973 epiphysis of phalanx of pes An epiphysis that is part of a distal phalanx of pes. http://purl.obolibrary.org/obo/UBERON_0011977 epiphysis of proximal phalanx of manus http://purl.obolibrary.org/obo/UBERON_0004387 epiphysis of phalanx of manus An epiphysis that is part of a proximal phalanx of manus. https://purl.brain-bican.org/ontology/dhbao/DHBA_10644 optic chiasm http://purl.obolibrary.org/obo/UBERON_0000959 optic chiasma http://purl.obolibrary.org/obo/UBERON_0011978 epiphysis of middle phalanx of manus http://purl.obolibrary.org/obo/UBERON_0004387 epiphysis of phalanx of manus An epiphysis that is part of a middle phalanx of manus. http://purl.obolibrary.org/obo/UBERON_0011979 epiphysis of distal phalanx of manus http://purl.obolibrary.org/obo/UBERON_0004387 epiphysis of phalanx of manus An epiphysis that is part of a distal phalanx of manus. http://purl.obolibrary.org/obo/UBERON_0037458 hair of neck http://purl.obolibrary.org/obo/UBERON_0001037 strand of hair http://purl.obolibrary.org/obo/UBERON_0011980 crurotarsal joint http://purl.obolibrary.org/obo/UBERON_0001488 ankle joint A joint that connects the bones of the crus to the proximal tarsal bones. http://purl.obolibrary.org/obo/UBERON_0011997 coelom http://purl.obolibrary.org/obo/UBERON_0000481 multi-tissue structure The aggregate of the coelemic cavity lumen plus the membranes that line the lumen. http://purl.obolibrary.org/obo/UBERON_0037459 hair of limb http://purl.obolibrary.org/obo/UBERON_0001037 strand of hair http://purl.obolibrary.org/obo/UBERON_0012054 myocoele http://purl.obolibrary.org/obo/UBERON_0002553 anatomical cavity The cavity within a myotome. http://purl.obolibrary.org/obo/UBERON_0012070 palatal tooth http://purl.obolibrary.org/obo/UBERON_0003267 tooth of upper jaw A tooth that is on the roof of the mouth. http://purl.obolibrary.org/obo/UBERON_0036268 pelvic vein http://purl.obolibrary.org/obo/UBERON_0001638 vein http://purl.obolibrary.org/obo/UBERON_0012071 palate bone http://purl.obolibrary.org/obo/UBERON_0008907 dermal bone Any bone that is part of a palate. http://purl.obolibrary.org/obo/UBERON_0012075 replacement bone http://purl.obolibrary.org/obo/UBERON_0010522 replacement element Bone that forms as a replacement of another structural tissue. http://purl.obolibrary.org/obo/UBERON_0039228 sigmoid vein http://purl.obolibrary.org/obo/UBERON_0001638 vein http://purl.obolibrary.org/obo/UBERON_0012080 patella cartilage element http://purl.obolibrary.org/obo/UBERON_0005863 cartilaginous condensation A cartilaginous condensation that has the potential to develop into a patella. http://purl.obolibrary.org/obo/UBERON_0012081 patella pre-cartilage condensation http://purl.obolibrary.org/obo/UBERON_0005866 pre-cartilage condensation A pre-cartilage condensation that has the potential to develop into a patella. https://purl.brain-bican.org/ontology/dhbao/DHBA_12139 temporal lobe http://purl.obolibrary.org/obo/UBERON_0001871 temporal lobe http://purl.obolibrary.org/obo/UBERON_0012082 bronchial lumen http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space An anatomical cavity that is part of a bronchus. http://purl.obolibrary.org/obo/UBERON_0012084 lumen of secondary bronchus http://purl.obolibrary.org/obo/UBERON_0012082 bronchial lumen An anatomical cavity that is part of a lobar bronchus. https://purl.brain-bican.org/ontology/mbao/MBA_567 Cerebrum https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions http://purl.obolibrary.org/obo/UBERON_0012085 lumen of tertiary bronchus http://purl.obolibrary.org/obo/UBERON_0012082 bronchial lumen An anatomical cavity that is part of a segmental bronchus. http://purl.obolibrary.org/obo/UBERON_0012102 buccal salivary gland http://purl.obolibrary.org/obo/UBERON_0001044 saliva-secreting gland A salivary gland that is part of a cheek. https://purl.brain-bican.org/ontology/dhbao/DHBA_10158 telencephalon http://purl.obolibrary.org/obo/UBERON_0001893 telencephalon http://purl.obolibrary.org/obo/UBERON_0012140 digitopodium region http://purl.obolibrary.org/obo/UBERON_0012139 segment of autopod A segment of the autopod consisting of both acropodial region and metapodial region, but excluding the mesopodial/basopodial region. http://purl.obolibrary.org/obo/UBERON_0012141 manual digitopodium region http://purl.obolibrary.org/obo/UBERON_0012140 digitopodium region A digitopodium region that is part of a manus[Obol]. This includes the fingers and metacarpal region, but excludes the carpal region. https://purl.brain-bican.org/ontology/mbao/MBA_1129 Interbrain https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions http://purl.obolibrary.org/obo/UBERON_0012142 pedal digitopodium region http://purl.obolibrary.org/obo/UBERON_0012140 digitopodium region A digitopodium region that is part of a pes[Obol]. This includes the toes and metatarsal region, but excludes the tarsals region. http://purl.obolibrary.org/obo/UBERON_0012150 skeleton of digitopodium http://purl.obolibrary.org/obo/UBERON_0010712 limb skeleton subdivision A subdivision of the autopod skeleton consisting of both acropodial skeleon and metapodial skeleton, but excluding the mesopodial/basopodial skeleton. http://purl.obolibrary.org/obo/UBERON_0012151 skeleton of manual digitopodium http://purl.obolibrary.org/obo/UBERON_0012150 skeleton of digitopodium A subdivision of the manus skeleton consisting of both manual acropodial skeleton and metacarpal skeleton, but excluding the carpal skeleton. https://purl.brain-bican.org/ontology/dhbao/DHBA_10389 diencephalon http://purl.obolibrary.org/obo/UBERON_0001894 diencephalon http://purl.obolibrary.org/obo/UBERON_0012152 skeleton of pedal digitopodium http://purl.obolibrary.org/obo/UBERON_0012150 skeleton of digitopodium A subdivision of the pes skeleton consisting of both pedal acropodial skeleton and metatarsal skeleton, but excluding the tarsal skeleton. http://purl.obolibrary.org/obo/UBERON_0012168 umbilical cord blood http://purl.obolibrary.org/obo/UBERON_0013755 arterial blood Blood that remains in the placenta and in the attached umbilical cord after childbirth[WP]. https://purl.brain-bican.org/ontology/dhbao/DHBA_10460 pineal body http://purl.obolibrary.org/obo/UBERON_0001905 pineal body http://purl.obolibrary.org/obo/UBERON_0012172 stomach primordium http://purl.obolibrary.org/obo/UBERON_0001048 primordium A primordium that has the potential to develop into a stomach. http://purl.obolibrary.org/obo/UBERON_0012177 skin apocrine gland http://purl.obolibrary.org/obo/UBERON_0019319 exocrine gland of integumental system An apocrine gland that is part of a skin of body. http://purl.obolibrary.org/obo/UBERON_0012180 head or neck skin http://purl.obolibrary.org/obo/UBERON_0000014 zone of skin A zone of skin that is part of a craniocervical region. https://purl.brain-bican.org/ontology/mbao/MBA_125 optic tract https://purl.brain-bican.org/ontology/mbao/MBA_1009 fiber tracts http://purl.obolibrary.org/obo/UBERON_0012186 ovary growing follicle http://purl.obolibrary.org/obo/UBERON_0001305 ovarian follicle An ovarian follicle undergoing maturation. http://purl.obolibrary.org/obo/UBERON_0012193 phrenic vein http://purl.obolibrary.org/obo/UBERON_0001638 vein The veins that run parallel to the phrenic arteries which include the two superior and two inferior phrenic veins. https://purl.brain-bican.org/ontology/dhbao/DHBA_10589 optic tract http://purl.obolibrary.org/obo/UBERON_0001908 optic tract http://purl.obolibrary.org/obo/UBERON_0012239 urinary bladder vasculature http://purl.obolibrary.org/obo/UBERON_0006876 vasculature of organ Network of tubes that carries blood through the distensible musculomembranous organ that serves to collect and store urine excreted by the kidneys[MP]. http://purl.obolibrary.org/obo/UBERON_0012240 urethral meatus http://purl.obolibrary.org/obo/UBERON_0010418 urethral opening External opening or orifice of the urethra through which urine and seminal fluid (in males only) leave the body; in males the meatus presents as a vertical slit normally positioned at the tip of glans penis; in females the meatus is located between the clitoris and the vagina in the vulvular vestibule of the female genitalia[MP]. https://purl.brain-bican.org/ontology/mbao/MBA_512 Cerebellum https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions http://purl.obolibrary.org/obo/UBERON_0012241 male urethral meatus http://purl.obolibrary.org/obo/UBERON_0012240 urethral meatus A urethral meatus that is part of a male urethra[Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0012242 internal urethral orifice http://purl.obolibrary.org/obo/UBERON_0010418 urethral opening The usually crescent-shaped opening of the urinary bladder into the urethra, placed at the anteroinferior angle (apex) of the urinary bladder trigone. https://purl.brain-bican.org/ontology/dhbao/DHBA_10656 cerebellum http://purl.obolibrary.org/obo/UBERON_0002037 cerebellum http://purl.obolibrary.org/obo/UBERON_0012246 thyroid follicular lumen http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space A follicular lumen is the closed cavity within a follicle of the thyroid gland. It is surrounded by follicular cells and filled with colloid, a concentrated solution of thyroglobulin. http://purl.obolibrary.org/obo/UBERON_0012247 cervical gland http://purl.obolibrary.org/obo/UBERON_0002451 endometrial gland Mucus-secreting glands in the mucosa of the uterine cervix. https://purl.brain-bican.org/ontology/mbao/MBA_81 lateral ventricle http://purl.obolibrary.org/obo/UBERON_0002285 telencephalic ventricle http://purl.obolibrary.org/obo/UBERON_0012248 cervical mucosa http://purl.obolibrary.org/obo/UBERON_0001295 endometrium Lining of the head of the uterus (cervix); contains large branched glands; does not undergo sloughing. http://purl.obolibrary.org/obo/UBERON_0012249 ectocervix http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure The part of the cervix uteri that protrudes into the vagina and is lined with stratified squamous epithelium. https://purl.brain-bican.org/ontology/dhbao/DHBA_10596 lateral ventricles http://purl.obolibrary.org/obo/UBERON_0002285 telencephalic ventricle http://purl.obolibrary.org/obo/UBERON_0012250 cervix glandular epithelium http://purl.obolibrary.org/obo/UBERON_0006799 glandular epithelium A glandular epithelium that is part of a uterine cervix. http://purl.obolibrary.org/obo/UBERON_0012251 ectocervical epithelium http://purl.obolibrary.org/obo/UBERON_0004801 cervix epithelium An epithelium that is part of a ectocervix. https://purl.brain-bican.org/ontology/mbao/MBA_129 third ventricle http://purl.obolibrary.org/obo/UBERON_0002286 third ventricle http://purl.obolibrary.org/obo/UBERON_0012252 endocervical epithelium http://purl.obolibrary.org/obo/UBERON_0012250 cervix glandular epithelium The glandular epithelium that lines the endocervix. http://purl.obolibrary.org/obo/UBERON_0012253 cervical squamo-columnar junction http://purl.obolibrary.org/obo/UBERON_0004801 cervix epithelium Region of cervical epithelium where columnar epithelium of endocervic and the stratified non-keratinising squamous epithelium of the ectocervic meet. https://purl.brain-bican.org/ontology/dhbao/DHBA_10602 third ventricle http://purl.obolibrary.org/obo/UBERON_0002286 third ventricle http://purl.obolibrary.org/obo/UBERON_0012254 abdominal aorta artery http://purl.obolibrary.org/obo/UBERON_0004573 systemic artery An artery that originates from the abdominal aorta. http://purl.obolibrary.org/obo/UBERON_0012274 columnar epithelium http://purl.obolibrary.org/obo/UBERON_0000483 epithelium An epithelium that consists of columnar epithelial cells. Columnar epithelia are epithelial cells whose heights are at least four times their width. Columnar epithelia are divided into simple (or unilayered), and the rarer stratified (or multi-layered).[WP, modified]. https://purl.brain-bican.org/ontology/dhbao/DHBA_10332 basal nuclei (basal ganglia) https://purl.brain-bican.org/ontology/dhbao/DHBA_10157 gray matter of forebrain http://purl.obolibrary.org/obo/UBERON_0012275 meso-epithelium http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure Epithelium that derives from the mesoderm. [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0012278 gland of nasal mucosa http://purl.obolibrary.org/obo/UBERON_0036225 respiratory system gland The nasal glands are the seromucous glands in the respiratory region of the nasal mucous membrane. The three major types of nasal glands are anterior serous glands, seromucous glands, and Bowman glands. https://purl.brain-bican.org/ontology/dhbao/DHBA_10658 cerebellar vermis http://purl.obolibrary.org/obo/UBERON_0004720 cerebellar vermis http://purl.obolibrary.org/obo/UBERON_0012279 chromaffin paraganglion http://purl.obolibrary.org/obo/UBERON_0034978 paraganglion (generic) Small bodies containing chromaffin cells occurring outside of the adrenal medulla, most commonly near the sympathetic ganglia and in organs such as the kidney, liver, heart and gonads. http://purl.obolibrary.org/obo/UBERON_0012287 Rathkes pouch epithelium http://purl.obolibrary.org/obo/UBERON_0011642 oral epithelium from ectoderm An epithelial sac that is part of a Rathke's pouch. http://purl.obolibrary.org/obo/PR_000044780 leukocyte immunoglobulin-like receptor subfamily member http://purl.obolibrary.org/obo/PR_000000001 protein http://purl.obolibrary.org/obo/UBERON_0012292 embryonic cloacal fold http://purl.obolibrary.org/obo/UBERON_0000481 multi-tissue structure One of the pair of mesenchymal swellings (folds) located on either side of the cloacal membrane during the indifferent stage of embryonic development; cranial to the cloacal membrane the folds unite to form the genital tubercle; caudally the folds are subdivided into urogenital folds anteriorly and anal folds posteriorly. http://purl.obolibrary.org/obo/UBERON_0012299 mucosa of urethra http://purl.obolibrary.org/obo/UBERON_0000344 mucosa A mucosa that is part of a urethra. http://purl.obolibrary.org/obo/CL_0010013 type I pinealocyte http://purl.obolibrary.org/obo/CL_0000652 pinealocyte http://purl.obolibrary.org/obo/UBERON_0012314 embryonic facial prominence http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure One of five swellings formed during the development of the face. http://purl.obolibrary.org/obo/UBERON_0012317 vagina orifice http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure The median slit located inferior and posterior to the external urethral orifice in the female; the exit for menstrual flow and birth and the entrance for the penis during sexual intercourse; the size and appearance of the vaginal orifice varies inversely with that of the hymen (G. membrane), a thin fold of mucous membrane that surrounds the vaginal orifice. http://purl.obolibrary.org/obo/CL_0010014 type II pinealocyte http://purl.obolibrary.org/obo/CL_0000652 pinealocyte http://purl.obolibrary.org/obo/UBERON_0012320 cervical artery http://purl.obolibrary.org/obo/UBERON_0003502 neck blood vessel An artery of the neck. http://purl.obolibrary.org/obo/UBERON_0012321 deep cervical artery http://purl.obolibrary.org/obo/UBERON_0012320 cervical artery The deep cervical artery (Profunda cervicalis) is an artery of the neck. http://purl.obolibrary.org/obo/CL_4023032 ON retinal ganglion cell http://purl.obolibrary.org/obo/CL_0000740 retinal ganglion cell http://purl.obolibrary.org/obo/UBERON_0012324 transverse cervical artery http://purl.obolibrary.org/obo/UBERON_0012320 cervical artery The transverse cervical artery (transverse artery of neck, transversa colli artery) is a branch of the thyrocervical trunk, running at a higher level than the suprascapular artery. http://purl.obolibrary.org/obo/UBERON_0012329 keratinized stratified squamous epithelium http://purl.obolibrary.org/obo/UBERON_0006915 stratified squamous epithelium Keratinized stratified squamous epithelium is a stratified squamous epithelium, the cells of which synthesize and accumulate keratin. https://purl.brain-bican.org/ontology/dhbao/DHBA_10505 pituitary body http://purl.obolibrary.org/obo/UBERON_0000007 pituitary gland http://purl.obolibrary.org/obo/UBERON_0012330 nasal-associated lymphoid tissue http://purl.obolibrary.org/obo/UBERON_0001962 gut-associated lymphoid tissue The lymphocytic cell population present in the mucosa of the nasopharyngeal duct of some animals. http://purl.obolibrary.org/obo/UBERON_0012344 holocrine gland http://purl.obolibrary.org/obo/UBERON_0002365 exocrine gland Any exocrine gland whose secretion consists of its own disintegrated secretory cells along with its secretory product; holocrine secretions are produced in the cytoplasm of the cell and released by the rupture of the plasma membrane, which destroys the cell and results in the secretion of the product into the lumen. http://purl.obolibrary.org/obo/UBERON_0012354 acropodium region http://purl.obolibrary.org/obo/UBERON_0012139 segment of autopod The segment of the autopod that is distal to the metapodial region and consists of the digits. http://purl.obolibrary.org/obo/UBERON_0035764 pulmonary lymph node http://purl.obolibrary.org/obo/UBERON_0000029 lymph node http://purl.obolibrary.org/obo/UBERON_0012355 manual acropodium region http://purl.obolibrary.org/obo/UBERON_0012354 acropodium region The segment of the manus that is distal to the metacarpal region and consists of the manual digits (fingers). http://purl.obolibrary.org/obo/UBERON_0012356 pedal acropodium region http://purl.obolibrary.org/obo/UBERON_0012354 acropodium region The segment of the pes that is distal to the metatarsal region and consists of the pedal digits (toes). https://purl.brain-bican.org/ontology/mbao/MBA_304325711 retina http://purl.obolibrary.org/obo/UBERON_0000966 retina http://purl.obolibrary.org/obo/UBERON_0012357 digitopodium bone http://purl.obolibrary.org/obo/UBERON_0011250 autopod bone A bone that is part of a the digitopodium skeleton - i.e. the acropodial skeleton or the metapodial skeleton. http://purl.obolibrary.org/obo/UBERON_0012358 manual digitopodium bone http://purl.obolibrary.org/obo/UBERON_0012357 digitopodium bone A bone that is part of a the manual digitopodium skeleton - i.e. the fingers or the metacarpal skeleton. http://purl.obolibrary.org/obo/UBERON_0012359 pedal digitopodium bone http://purl.obolibrary.org/obo/UBERON_0012357 digitopodium bone A bone that is part of a the pedal digitopodium skeleton - i.e. the toes or the metatarsal skeleton. http://purl.obolibrary.org/obo/UBERON_0039261 pancreatic artery http://purl.obolibrary.org/obo/UBERON_0001637 artery http://purl.obolibrary.org/obo/UBERON_0012360 bone of jaw http://purl.obolibrary.org/obo/UBERON_0013765 digestive system element A bone element that is part of a jaw region. http://purl.obolibrary.org/obo/UBERON_0012363 thyroid follicle epithelium http://purl.obolibrary.org/obo/UBERON_0005911 endo-epithelium An epithelium that is part of a thyroid follicle. http://purl.obolibrary.org/obo/UBERON_0035039 rectal artery http://purl.obolibrary.org/obo/UBERON_0001637 artery http://purl.obolibrary.org/obo/UBERON_0012367 muscle layer of intestine http://purl.obolibrary.org/obo/UBERON_0018261 muscular coat of digestive tract A muscle layer that is part of an intestine. http://purl.obolibrary.org/obo/UBERON_0012368 circular muscle layer of muscular coat http://purl.obolibrary.org/obo/UBERON_0034933 layer of smooth muscle tissue The inner layer of the muscular coat. https://purl.brain-bican.org/ontology/dhbao/DHBA_12131 parietal lobe http://purl.obolibrary.org/obo/UBERON_0001872 parietal lobe http://purl.obolibrary.org/obo/UBERON_0012369 longitudinal muscle layer of muscular coat http://purl.obolibrary.org/obo/UBERON_0034933 layer of smooth muscle tissue The outer layer of the muscular coat. http://purl.obolibrary.org/obo/UBERON_0012373 sympathetic nerve plexus http://purl.obolibrary.org/obo/UBERON_0001816 autonomic nerve plexus A nerve plexus that is part of a sympathetic nervous system. http://purl.obolibrary.org/obo/UBERON_0035767 intrapulmonary bronchus http://purl.obolibrary.org/obo/UBERON_0002185 bronchus http://purl.obolibrary.org/obo/UBERON_0012375 subserosa http://purl.obolibrary.org/obo/UBERON_0004923 organ component layer A layer of tissue between the muscularis and serosa. http://purl.obolibrary.org/obo/UBERON_0012377 muscle layer of jejunum http://purl.obolibrary.org/obo/UBERON_0011201 muscle layer of small intestine A muscular coat that is part of a jejunum. https://purl.brain-bican.org/ontology/dhbao/DHBA_12890 spinal cord http://purl.obolibrary.org/obo/UBERON_0002240 spinal cord http://purl.obolibrary.org/obo/UBERON_0012378 muscle layer of urinary bladder http://purl.obolibrary.org/obo/UBERON_0006660 muscular coat A muscular coat that is part of a urinary bladder. http://purl.obolibrary.org/obo/UBERON_0012398 large intestine smooth muscle circular layer http://purl.obolibrary.org/obo/UBERON_0012368 circular muscle layer of muscular coat A circular muscle layer of muscular coat that is part of a large intestine smooth muscle. https://purl.brain-bican.org/ontology/mbao/MBA_343 Brain stem https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions http://purl.obolibrary.org/obo/UBERON_0012399 large intestine smooth muscle longitudinal layer http://purl.obolibrary.org/obo/UBERON_0012369 longitudinal muscle layer of muscular coat A longitudinal muscle layer of muscular coat that is part of a large intestine smooth muscle. http://purl.obolibrary.org/obo/UBERON_0012401 small intestine smooth muscle circular layer http://purl.obolibrary.org/obo/UBERON_0012368 circular muscle layer of muscular coat A circular muscle layer of muscular coat that is part of a small intestine smooth muscle. https://purl.brain-bican.org/ontology/mbao/MBA_776 corpus callosum https://purl.brain-bican.org/ontology/mbao/MBA_1009 fiber tracts http://purl.obolibrary.org/obo/UBERON_0012402 small intestine smooth muscle longitudinal layer http://purl.obolibrary.org/obo/UBERON_0012369 longitudinal muscle layer of muscular coat A longitudinal muscle layer of muscular coat that is part of a small intestine smooth muscle. http://purl.obolibrary.org/obo/UBERON_0012418 respiratory system venous smooth muscle http://purl.obolibrary.org/obo/UBERON_0004696 venous system smooth muscle A smooth muscle tissue that is part of a respiratory system venous blood vessel. http://purl.obolibrary.org/obo/UBERON_0012419 taenia coli http://purl.obolibrary.org/obo/UBERON_0034933 layer of smooth muscle tissue The taeniae coli (also teniae coli) are three separate longitudinal ribbons of smooth muscle on the outside of the ascending, transverse, descending and sigmoid colons. They are visible, and can be seen just below the serosa or fibrosa. They are the Mesocolic, Free and Omental Coli. The teniae coli contracts length wise to produce the haustra, the bulges in the colon. The bands converge at the root of the vermiform appendix and the rectum. These bands correspond to the outer layer of the muscularis externa, in other portions of the digestive tract. https://purl.brain-bican.org/ontology/dhbao/DHBA_10561 corpus callosum http://purl.obolibrary.org/obo/UBERON_0002336 corpus callosum http://purl.obolibrary.org/obo/UBERON_0012423 layer of microvilli http://purl.obolibrary.org/obo/UBERON_0005162 multi cell part structure A layer of microvilli, Thin cylindrical membrane-covered projections on the surface of an animal cell containing a core bundle of actin filaments[GO,modified]. http://purl.obolibrary.org/obo/UBERON_0012425 striated border microvillus layer http://purl.obolibrary.org/obo/UBERON_0012423 layer of microvilli A microvillus layer that is striated and found in the intestine. https://purl.brain-bican.org/ontology/dhbao/DHBA_12113 frontal lobe http://purl.obolibrary.org/obo/UBERON_0016525 frontal lobe http://purl.obolibrary.org/obo/UBERON_0012429 hematopoietic tissue http://purl.obolibrary.org/obo/UBERON_0034769 lymphomyeloid tissue Blood-forming tissue, consisting of reticular fibers and cells. http://purl.obolibrary.org/obo/UBERON_0012430 tunica fibrosa of eyeball http://purl.obolibrary.org/obo/UBERON_0010314 structure with developmental contribution from neural crest The sclera and cornea form the fibrous tunic of the bulb of the eye; the sclera is opaque, and constitutes the posterior five-sixths of the tunic; the cornea is transparent, and forms the anterior sixth. https://purl.brain-bican.org/ontology/dhbao/DHBA_12682 intermediate (mantle) zone of hindbrain http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure http://purl.obolibrary.org/obo/UBERON_0012441 endothelium of peritubular capillary http://purl.obolibrary.org/obo/UBERON_0004819 kidney epithelium An endothelium that is part of a peritubular capillary. http://purl.obolibrary.org/obo/UBERON_0012463 cloacal lumen http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space An anatomical space that is enclosed by a cloaca. http://purl.obolibrary.org/obo/NCBITaxon_9685 Felis catus http://purl.obolibrary.org/obo/NCBITaxon_9682 Felis http://purl.obolibrary.org/obo/UBERON_0012464 cloacal vent http://purl.obolibrary.org/obo/UBERON_0000161 orifice The opening of the cloacal chamber to the outside of the organism. Birds maintain a single cloacal opening throughout their lives. http://purl.obolibrary.org/obo/UBERON_0012465 lumen of terminal part of digestive tract http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space An anatomical space that is enclosed by a terminal part of digestive tract. http://purl.obolibrary.org/obo/NCBITaxon_142796 Eumycetozoa http://purl.obolibrary.org/obo/NCBITaxon_2605435 Evosea http://purl.obolibrary.org/obo/UBERON_0012467 enclosed anatomical space http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space An anatomical space with no opening to another space or to the exterior. http://purl.obolibrary.org/obo/UBERON_0012468 anal tooth http://purl.obolibrary.org/obo/UBERON_0003913 tooth-like structure Triangular calcified papillae (often five) placed radially around the anus of some Holothuriidae. https://purl.brain-bican.org/ontology/mbao/MBA_500 Somatomotor areas https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions http://purl.obolibrary.org/obo/UBERON_0012475 skeleton of pectoral complex http://purl.obolibrary.org/obo/UBERON_0010912 subdivision of skeleton The collection of all skeletal elements in a pectoral complex - i.e. the combination of free limb or fin plus pectoral girdle. http://purl.obolibrary.org/obo/UBERON_0012476 skeleton of pelvic complex http://purl.obolibrary.org/obo/UBERON_0010912 subdivision of skeleton The collection of all skeletal elements in a pelvic complex - i.e. the combination of free limb or fin plus pelvic girdle. http://purl.obolibrary.org/obo/NCBITaxon_6236 Rhabditida http://purl.obolibrary.org/obo/NCBITaxon_119089 Chromadorea http://purl.obolibrary.org/obo/UBERON_0012477 dorsal part of neck http://purl.obolibrary.org/obo/UBERON_0005434 cervical region The posterior region of the neck, including the suboccipital region. http://purl.obolibrary.org/obo/UBERON_0012478 cloacal gland http://purl.obolibrary.org/obo/UBERON_0003408 gland of digestive tract A gland that is part of a cloaca. http://purl.obolibrary.org/obo/NCBITaxon_554915 Amoebozoa http://purl.obolibrary.org/obo/NCBITaxon_2759 Eukaryota http://purl.obolibrary.org/obo/UBERON_0012480 cloacal mucosa http://purl.obolibrary.org/obo/UBERON_0000344 mucosa A mucosa that is part of a cloaca [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0012481 cloacal epithelium http://purl.obolibrary.org/obo/UBERON_0005911 endo-epithelium An epithelium that is part of a cloaca. http://purl.obolibrary.org/obo/NCBITaxon_33554 Carnivora http://purl.obolibrary.org/obo/NCBITaxon_314145 Laurasiatheria http://purl.obolibrary.org/obo/UBERON_0012482 submucosa of cloaca http://purl.obolibrary.org/obo/UBERON_0018257 submucosa of digestive tract A submucosa that is part of a cloaca [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0012483 serosa of cloaca http://purl.obolibrary.org/obo/UBERON_0000042 serous membrane A serous membrane that is part of a cloaca [Automatically generated definition]. http://purl.obolibrary.org/obo/NCBITaxon_9787 Perissodactyla http://purl.obolibrary.org/obo/NCBITaxon_314145 Laurasiatheria http://purl.obolibrary.org/obo/UBERON_0012486 muscle layer of cloaca http://purl.obolibrary.org/obo/UBERON_0018261 muscular coat of digestive tract A muscular coat that is part of a cloaca. http://purl.obolibrary.org/obo/UBERON_0012487 vaginal sphincter http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure A sphincter muscle that is part of a vagina. http://purl.obolibrary.org/obo/NCBITaxon_9443 Primates http://purl.obolibrary.org/obo/NCBITaxon_314146 Euarchontoglires http://purl.obolibrary.org/obo/UBERON_0012488 muscle layer of duodenum http://purl.obolibrary.org/obo/UBERON_0011201 muscle layer of small intestine A muscular coat that is part of a duodenum. http://purl.obolibrary.org/obo/UBERON_0012489 muscle layer of colon http://purl.obolibrary.org/obo/UBERON_0011198 muscle layer of large intestine A muscular coat that is part of a colon. http://purl.obolibrary.org/obo/UBERON_0012490 muscle layer of anal canal http://purl.obolibrary.org/obo/UBERON_0011198 muscle layer of large intestine A muscular coat that is part of a anal canal. http://purl.obolibrary.org/obo/NCBITaxon_9975 Lagomorpha http://purl.obolibrary.org/obo/NCBITaxon_314147 Glires http://purl.obolibrary.org/obo/UBERON_0012494 muscularis mucosae of duodenum http://purl.obolibrary.org/obo/UBERON_0001210 muscularis mucosae of small intestine A muscularis mucosa that is part of a duodenum. http://purl.obolibrary.org/obo/UBERON_0012497 muscularis mucosae of rectum http://purl.obolibrary.org/obo/UBERON_0018112 rectum smooth muscle tissue A muscularis mucosa that is part of a rectum. http://purl.obolibrary.org/obo/NCBITaxon_2697495 Spiralia http://purl.obolibrary.org/obo/NCBITaxon_33317 Protostomia http://purl.obolibrary.org/obo/UBERON_0012498 serosa of appendix http://purl.obolibrary.org/obo/UBERON_0001209 serosa of large intestine A serous membrane that is part of a vermiform appendix. http://purl.obolibrary.org/obo/UBERON_0012499 serosa of fallopian tube http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure A serous membrane that is part of a fallopian tube. http://purl.obolibrary.org/obo/NCBITaxon_7586 Echinodermata http://purl.obolibrary.org/obo/NCBITaxon_33511 Deuterostomia http://purl.obolibrary.org/obo/UBERON_0012503 serosa of fundus of stomach http://purl.obolibrary.org/obo/UBERON_0001201 serosa of stomach A serous membrane that is part of a fundus of stomach. http://purl.obolibrary.org/obo/UBERON_0012504 adventitia of esophagus http://purl.obolibrary.org/obo/UBERON_0005742 adventitia An adventitia that is part of a esophagus. http://purl.obolibrary.org/obo/NCBITaxon_147554 Schizosaccharomycetes http://purl.obolibrary.org/obo/NCBITaxon_451866 Taphrinomycotina http://purl.obolibrary.org/obo/UBERON_0012615 umbilical smooth muscle http://purl.obolibrary.org/obo/UBERON_0005292 extraembryonic tissue A smooth muscle tissue that is part of a umbilical cord. http://purl.obolibrary.org/obo/UBERON_0012650 gastroduodenal junction http://purl.obolibrary.org/obo/UBERON_1100000 digestive tract junction An anatomical junction that connects a stomach and connects a duodenum. http://purl.obolibrary.org/obo/NCBITaxon_6073 Cnidaria http://purl.obolibrary.org/obo/NCBITaxon_6072 Eumetazoa http://purl.obolibrary.org/obo/UBERON_0012651 mucosa of gastroduodenal junction http://purl.obolibrary.org/obo/UBERON_0001199 mucosa of stomach A mucosa that is part of a gastroduodenal junction. http://purl.obolibrary.org/obo/UBERON_0013118 sulcus of brain http://purl.obolibrary.org/obo/UBERON_0000093 sulcus A depression or fissure in the surface of the brain. It surrounds the gyri, creating the characteristic appearance of the brain in humans and other large mammals. http://purl.obolibrary.org/obo/UBERON_0036553 wall of synovial tendon sheath http://purl.obolibrary.org/obo/UBERON_0000060 anatomical wall http://purl.obolibrary.org/obo/UBERON_0013126 vein of abdomen http://purl.obolibrary.org/obo/UBERON_0003497 abdomen blood vessel A vein that is part of a abdomen. http://purl.obolibrary.org/obo/UBERON_0013127 pulmonary venous system http://purl.obolibrary.org/obo/UBERON_0002049 vasculature The part of the venous system that drains the lungs[Kardong]. https://purl.brain-bican.org/ontology/mbao/MBA_1099 fornix system https://purl.brain-bican.org/ontology/mbao/MBA_1009 fiber tracts http://purl.obolibrary.org/obo/UBERON_0013136 vein of lip http://purl.obolibrary.org/obo/UBERON_0001638 vein A vein that drains a lip. http://purl.obolibrary.org/obo/UBERON_0013139 ligament of liver http://purl.obolibrary.org/obo/UBERON_0013765 digestive system element A nonskeletal ligament that is part of a liver. https://purl.brain-bican.org/ontology/dhbao/DHBA_10576 fornix http://purl.obolibrary.org/obo/UBERON_0000052 fornix of brain http://purl.obolibrary.org/obo/UBERON_0013140 systemic vein http://purl.obolibrary.org/obo/UBERON_0001638 vein Any vein within the general circulation that transports blood back to the right atrium of the heart. http://purl.obolibrary.org/obo/UBERON_0013151 choroidal artery http://purl.obolibrary.org/obo/UBERON_0001637 artery One of two arteries (anterior and posterior choroidal artery) that supply blood to the choroid plexus, optic tract, hippocampus, globus pallidus, and other various brain regions. http://purl.obolibrary.org/obo/UBERON_0035074 duct of apocrine sweat gland http://purl.obolibrary.org/obo/UBERON_0000058 duct http://purl.obolibrary.org/obo/UBERON_0013158 foregut-midgut junction gland http://purl.obolibrary.org/obo/UBERON_0003408 gland of digestive tract A gland that is part of a foregut-midgut junction. http://purl.obolibrary.org/obo/UBERON_0013161 left lateral ventricle http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure A telencephalic ventricle that is in_the_left_side_of a telencephalon. http://purl.obolibrary.org/obo/UBERON_0035050 excretory duct http://purl.obolibrary.org/obo/UBERON_0000058 duct http://purl.obolibrary.org/obo/UBERON_0013162 right lateral ventricle http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure A telencephalic ventricle that is in_the_right_side_of a telencephalon. http://purl.obolibrary.org/obo/UBERON_0013191 ovarian cortex http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure The layer of the ovarian stroma lying immediately beneath the tunica albuginea, composed of connective tissue cells and fibers, among which are scattered primary and secondary (antral) follicles in various stages of development; the cortex varies in thickness according to the age of the individual, becoming thinner with advancing years; included in the follicles are the cumulus oophorus, membrana granulosa (and the granulosa cells inside it), corona radiata, zona pellucida, and primary oocyte; the zona pellucida, theca of follicle, antrum and liquor folliculi are also contained in the follicle; also in the cortex is the corpus luteum derived from the follicles. http://purl.obolibrary.org/obo/UBERON_0036441 wall of fallopian tube http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure http://purl.obolibrary.org/obo/UBERON_0013192 ovarian medulla http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure Highly vascular stroma found in the center of the ovary that forms from embryonic mesenchyme and contains blood vessels, lymphatic vessels, and nerves; this stroma forms the tissue of the hilum by which the ovarian ligament is attached, and through which the blood vessels enter; it does not contain any ovarian follicles. http://purl.obolibrary.org/obo/UBERON_0013212 anal sac gland secretion http://purl.obolibrary.org/obo/UBERON_0000456 secretion of exocrine gland A bodily secretion that is produced by a gland of anal sac. http://purl.obolibrary.org/obo/UBERON_0036521 wall of urethra http://purl.obolibrary.org/obo/UBERON_0000060 anatomical wall http://purl.obolibrary.org/obo/UBERON_0013228 sweat gland of eyelid http://purl.obolibrary.org/obo/UBERON_0013229 eyelid gland Glands of Moll, also known as ciliary glands, are modified apocrine sweat glands that are found on the margin of the eyelid. They are next to the base of the eyelashes, and anterior to the Meibomian glands within the distal eyelid margin. These glands are relatively large and tubular-shaped. The glands of Moll are named after Dutch oculist Jacob Anton Moll (1832-1914). Glands of Moll empty into the adjacent lashes. Glands of Moll and Zeis secrete lipid that adds to the superficial layer of the tear film, retarding evaporation. The glands of Moll are prone to infection and blockage of its duct with sebum and cell debris. Blockage of the gland's duct causes swelling which can manifest itself as a stye. http://purl.obolibrary.org/obo/UBERON_0013229 eyelid gland http://purl.obolibrary.org/obo/UBERON_0015152 gland of ocular region Any gland that is part of an eyelid. This includes sebaceous glands (Zeis gland, tarsal gland) and sweat glands (Moll's gland). http://purl.obolibrary.org/obo/UBERON_0036523 wall of vagina http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure http://purl.obolibrary.org/obo/UBERON_0013231 sebaceous gland of eyelid http://purl.obolibrary.org/obo/UBERON_0013229 eyelid gland Any of the sebaceous glands that are in the eyelid. Examples: gland of Zeis (services eyelashes), gland of Meibom (tarsal gland - unconnected to eyelids). http://purl.obolibrary.org/obo/UBERON_0013232 serous acinus http://purl.obolibrary.org/obo/UBERON_0011858 acinus of exocrine gland The secretory unit of a serous gland. The acinar portion is composed of serous secreting cells. http://purl.obolibrary.org/obo/UBERON_0036658 wall of central canal of spinal cord http://purl.obolibrary.org/obo/UBERON_0005358 ventricle of nervous system http://purl.obolibrary.org/obo/UBERON_0013235 ventrum http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision A major organism subdivisionthat is the entire part of an anatomical structure ventral to a horizontal plane and bounded on one side by the same horizontal plane. http://purl.obolibrary.org/obo/UBERON_0013239 future glans penis http://purl.obolibrary.org/obo/UBERON_0013238 future glans A future glans that is part of a male genital tubercle. http://purl.obolibrary.org/obo/UBERON_0036661 wall of ventricular system of brain http://purl.obolibrary.org/obo/UBERON_0005358 ventricle of nervous system http://purl.obolibrary.org/obo/UBERON_0013240 future glans clitoris http://purl.obolibrary.org/obo/UBERON_0013238 future glans A future glans that is part of a female genital tubercle. http://purl.obolibrary.org/obo/UBERON_0013241 embryonic urethral groove http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure The precursor of the urethra. http://purl.obolibrary.org/obo/UBERON_0013247 male paramesonephric duct http://purl.obolibrary.org/obo/UBERON_0012275 meso-epithelium An epithelial tube that develops from a Mullerian duct in a male. Later degenerates. http://purl.obolibrary.org/obo/UBERON_0036925 wall of eyeball http://purl.obolibrary.org/obo/UBERON_0000060 anatomical wall http://purl.obolibrary.org/obo/UBERON_0013279 diaphysis of fibula http://purl.obolibrary.org/obo/UBERON_0004769 diaphysis A diaphysis that is part of a fibula[Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0013280 diaphysis of tibia http://purl.obolibrary.org/obo/UBERON_0004769 diaphysis A diaphysis that is part of a tibia. http://purl.obolibrary.org/obo/UBERON_0036990 wall of pharyngotympanic tube http://purl.obolibrary.org/obo/UBERON_0000060 anatomical wall http://purl.obolibrary.org/obo/UBERON_0013411 cranial cavity http://purl.obolibrary.org/obo/UBERON_0002553 anatomical cavity Anatomical cavity that is the lumen of the skull and contains the brain. http://purl.obolibrary.org/obo/UBERON_0013478 cecal tonsil http://purl.obolibrary.org/obo/UBERON_0001962 gut-associated lymphoid tissue A thickened round patch of lymphoid tissue located at the ileocecal junction adjacent to the sacculus rotundus. http://purl.obolibrary.org/obo/UBERON_0037089 wall of orbit http://purl.obolibrary.org/obo/UBERON_0000075 subdivision of skeletal system http://purl.obolibrary.org/obo/UBERON_0013479 lung endothelium http://purl.obolibrary.org/obo/UBERON_0004702 respiratory system blood vessel endothelium A blood vessel endothelium that is part of a lung [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0013481 crypt of Lieberkuhn of ileum http://purl.obolibrary.org/obo/UBERON_0001241 crypt of Lieberkuhn of small intestine An intestinal crypt that is located in the ileum. http://purl.obolibrary.org/obo/UBERON_0037191 wall of membranous labyrinth http://purl.obolibrary.org/obo/UBERON_0000060 anatomical wall http://purl.obolibrary.org/obo/UBERON_0013482 crypt of Lieberkuhn of duodenum http://purl.obolibrary.org/obo/UBERON_0001241 crypt of Lieberkuhn of small intestine An intestinal crypt that is located in the duodenum. http://purl.obolibrary.org/obo/UBERON_0013483 crypt of Lieberkuhn of jejunum http://purl.obolibrary.org/obo/UBERON_0001241 crypt of Lieberkuhn of small intestine An intestinal crypt that is located in the jejunum. http://purl.obolibrary.org/obo/UBERON_0013485 crypt of Lieberkuhn of colon http://purl.obolibrary.org/obo/UBERON_0001984 crypt of Lieberkuhn of large intestine An intestinal crypt that is located in the colon. The colonic crypts of Lieberkühn are straight and unbranched and lined largely with goblet cells. http://purl.obolibrary.org/obo/UBERON_0037237 wall of lacrimal duct http://purl.obolibrary.org/obo/UBERON_0000060 anatomical wall http://purl.obolibrary.org/obo/UBERON_0013486 crypt of Lieberkuhn of appendix http://purl.obolibrary.org/obo/UBERON_0001984 crypt of Lieberkuhn of large intestine An intestinal crypt that is located in the appendix. http://purl.obolibrary.org/obo/UBERON_0013491 cervical fascia http://purl.obolibrary.org/obo/UBERON_0008982 fascia Any fascia tissue that is part of the neck region. http://purl.obolibrary.org/obo/UBERON_0035965 wall of blood vessel http://purl.obolibrary.org/obo/UBERON_0000060 anatomical wall http://purl.obolibrary.org/obo/UBERON_0013493 abdominal fascia http://purl.obolibrary.org/obo/UBERON_0008982 fascia A fascia that is part of a abdomen. http://purl.obolibrary.org/obo/UBERON_0013501 cloacal sphincter http://purl.obolibrary.org/obo/UBERON_0014783 cloacal muscle A sphincter muscle that is part of a cloaca. http://purl.obolibrary.org/obo/UBERON_0034944 zone of organ http://purl.obolibrary.org/obo/UBERON_0000064 organ part http://purl.obolibrary.org/obo/UBERON_0013502 5th arch mesenchyme http://purl.obolibrary.org/obo/UBERON_0009494 pharyngeal arch mesenchymal region A mesenchyme that is part of a pharyngeal arch 5. http://purl.obolibrary.org/obo/UBERON_0013503 caudal vertebra cartilage element http://purl.obolibrary.org/obo/UBERON_2001457 postcranial axial cartilage A caudal vertebra endochondral element that is composed primarily of cartilage tissue. https://purl.brain-bican.org/ontology/mbao/MBA_1009 fiber tracts http://purl.obolibrary.org/obo/UBERON_0011215 central nervous system cell part cluster http://purl.obolibrary.org/obo/UBERON_0013504 caudal vertebra pre-cartilage condensation http://purl.obolibrary.org/obo/UBERON_0018142 caudal vertebra endochondral element A caudal vertebra endochondral element that is composed primarily of a pre-cartilage condensation. http://purl.obolibrary.org/obo/UBERON_0013505 cervical vertebra cartilage element http://purl.obolibrary.org/obo/UBERON_2001457 postcranial axial cartilage A cervical vertebra endochondral element that is composed primarily of cartilage tissue. https://purl.brain-bican.org/ontology/dhbao/DHBA_12420 facial nucleus http://purl.obolibrary.org/obo/UBERON_0000127 facial nucleus http://purl.obolibrary.org/obo/UBERON_0013506 cervical vertebra pre-cartilage condensation http://purl.obolibrary.org/obo/UBERON_0015007 cervical vertebra endochondral element A cervical vertebra endochondral element that is composed primarily of a pre-cartilage condensation. http://purl.obolibrary.org/obo/UBERON_0013507 thoracic vertebra cartilage element http://purl.obolibrary.org/obo/UBERON_2001457 postcranial axial cartilage A thoracic vertebra endochondral element that is composed primarily of cartilage tissue. http://purl.obolibrary.org/obo/UBERON_0036253 orifice of skull http://purl.obolibrary.org/obo/UBERON_0000161 orifice http://purl.obolibrary.org/obo/UBERON_0013508 thoracic vertebra pre-cartilage condensation http://purl.obolibrary.org/obo/UBERON_0015008 thoracic vertebra endochondral element A thoracic vertebra endochondral element that is composed primarily of a pre-cartilage condensation. http://purl.obolibrary.org/obo/UBERON_0013509 lumbar vertebra cartilage element http://purl.obolibrary.org/obo/UBERON_2001457 postcranial axial cartilage A lumbar vertebra endochondral element that is composed primarily of cartilage tissue. https://purl.brain-bican.org/ontology/dhbao/DHBA_10295 dentate area (dentate gyrus) http://purl.obolibrary.org/obo/UBERON_0001885 dentate gyrus of hippocampal formation http://purl.obolibrary.org/obo/UBERON_0013510 lumbar vertebra pre-cartilage condensation http://purl.obolibrary.org/obo/UBERON_0015009 lumbar vertebra endochondral element A lumbar vertebra endochondral element that is composed primarily of a pre-cartilage condensation. http://purl.obolibrary.org/obo/UBERON_0013514 space surrounding organism http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space The space that surrounds an organism. http://purl.obolibrary.org/obo/UBERON_0039175 subarachnoid space of brain http://purl.obolibrary.org/obo/UBERON_0000315 subarachnoid space http://purl.obolibrary.org/obo/UBERON_0013515 subdivision of oviduct http://purl.obolibrary.org/obo/UBERON_0013522 subdivision of tube A section through the tube or network of tubes that connects the ovaries to the outside of the body. http://purl.obolibrary.org/obo/UBERON_0039176 subarachnoid space of spinal cord http://purl.obolibrary.org/obo/UBERON_0000315 subarachnoid space http://purl.obolibrary.org/obo/UBERON_0036328 wall of coronary artery http://purl.obolibrary.org/obo/UBERON_0037144 wall of heart http://purl.obolibrary.org/obo/UBERON_0013525 stomach lumen http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space The anatomical space that is enclosed by a stomach. http://purl.obolibrary.org/obo/UBERON_0036351 wall of brachiocephalic artery http://purl.obolibrary.org/obo/UBERON_0000415 artery wall http://purl.obolibrary.org/obo/UBERON_0013526 otocyst lumen http://purl.obolibrary.org/obo/UBERON_0007473 lumen of epithelial sac An anatomical cavity that is part of a ear vesicle. http://purl.obolibrary.org/obo/UBERON_0036352 wall of subclavian artery http://purl.obolibrary.org/obo/UBERON_0000415 artery wall http://purl.obolibrary.org/obo/UBERON_0013630 short bone http://purl.obolibrary.org/obo/UBERON_0001474 bone element Short bones are designated as those bones that are as wide as they are long. Their primary function is to provide support and stability with little to no movement. They are one of five types of bones: long, short, flat, irregular and sesamoid. Examples of these bones include the tarsals in the foot and the carpals in the hand. http://purl.obolibrary.org/obo/UBERON_0036422 wall of pulmonary artery http://purl.obolibrary.org/obo/UBERON_0000415 artery wall http://purl.obolibrary.org/obo/UBERON_0037094 wall of common carotid artery http://purl.obolibrary.org/obo/UBERON_0000415 artery wall http://purl.obolibrary.org/obo/UBERON_0013631 sesamoid element http://purl.obolibrary.org/obo/UBERON_0010911 ossicle Ossicle that develops within bands of dense, regular connective tissue (e.g., tendons and ligaments). Sesamoids are generally located proximate to a bony prominence, over which the dense regular connective tissue wraps, and/or a joint or articulation. https://purl.brain-bican.org/ontology/mbao/MBA_158 posterior commissure https://purl.brain-bican.org/ontology/mbao/MBA_1009 fiber tracts http://purl.obolibrary.org/obo/UBERON_0013632 sesamoid cartilage http://purl.obolibrary.org/obo/UBERON_0013631 sesamoid element A sesamoid element that is composed primarily of cartilage tissue. https://purl.brain-bican.org/ontology/dhbao/DHBA_10567 posterior commissure http://purl.obolibrary.org/obo/UBERON_0000936 posterior commissure http://purl.obolibrary.org/obo/UBERON_0013636 epithelium of intestinal villus http://purl.obolibrary.org/obo/UBERON_0001902 epithelium of small intestine An epithelium that is part of a intestinal villus. https://purl.brain-bican.org/ontology/mbao/MBA_848 optic nerve https://purl.brain-bican.org/ontology/mbao/MBA_1009 fiber tracts http://purl.obolibrary.org/obo/UBERON_0013637 prostate gland lateral lobe http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure The prostate gland lobe that is located on the lateral side of the organ. https://purl.brain-bican.org/ontology/dhbao/DHBA_15544 optic nerve http://purl.obolibrary.org/obo/UBERON_0000941 cranial nerve II https://purl.brain-bican.org/ontology/mbao/MBA_688 Cerebral cortex http://purl.obolibrary.org/obo/UBERON_0000956 cerebral cortex http://purl.obolibrary.org/obo/UBERON_0013683 left dorsal thalamus http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure A dorsal thalamus that is in_the_left_side_of a diencephalon. https://purl.brain-bican.org/ontology/dhbao/DHBA_10159 cerebral cortex http://purl.obolibrary.org/obo/UBERON_0000956 cerebral cortex http://purl.obolibrary.org/obo/UBERON_0013684 right dorsal thalamus http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure A dorsal thalamus that is in_the_right_side_of a diencephalon. https://purl.brain-bican.org/ontology/mbao/MBA_771 Pons https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions http://purl.obolibrary.org/obo/UBERON_0013685 foramen of skull http://purl.obolibrary.org/obo/UBERON_0005744 bone foramen Anatomical space that is an opening in a bone of the skull. https://purl.brain-bican.org/ontology/dhbao/DHBA_10661 pons http://purl.obolibrary.org/obo/UBERON_0000988 pons http://purl.obolibrary.org/obo/UBERON_0013686 anatomical conduit space http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space An anatomical space which is the lumen of some anatomical conduit and connects two or more spaces together[FMA,modified]. https://purl.brain-bican.org/ontology/dhbao/DHBA_10154 neural tube http://purl.obolibrary.org/obo/UBERON_0001049 neural tube https://purl.brain-bican.org/ontology/mbao/MBA_1049 Flocculus https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions http://purl.obolibrary.org/obo/UBERON_0013687 pericranium http://purl.obolibrary.org/obo/UBERON_0002515 periosteum Periosteum that is part of a skull. http://purl.obolibrary.org/obo/UBERON_0036337 wall of appendix http://purl.obolibrary.org/obo/UBERON_0001169 wall of large intestine http://purl.obolibrary.org/obo/UBERON_0013688 tonsil germinal center http://purl.obolibrary.org/obo/UBERON_0010754 germinal center A germinal center that is part of a tonsil. http://purl.obolibrary.org/obo/UBERON_0013689 appendix lymphoid tissue http://purl.obolibrary.org/obo/UBERON_0001744 lymphoid tissue Lymphoid tissue located in the appendix. http://purl.obolibrary.org/obo/UBERON_0036362 wall of anal canal http://purl.obolibrary.org/obo/UBERON_0001169 wall of large intestine http://purl.obolibrary.org/obo/UBERON_0034997 renal medulla loop of Henle http://purl.obolibrary.org/obo/UBERON_0001288 loop of Henle http://purl.obolibrary.org/obo/UBERON_0013694 brain endothelium http://purl.obolibrary.org/obo/UBERON_0001986 endothelium Vascular endothelium found in blood vessels of the blood-brain-barrier. https://purl.brain-bican.org/ontology/mbao/MBA_985 Primary motor area https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions http://purl.obolibrary.org/obo/UBERON_0013695 colon endothelium http://purl.obolibrary.org/obo/UBERON_0001986 endothelium Vascular endothelium found in colon blood vessels. https://purl.brain-bican.org/ontology/dhbao/DHBA_10162 posterior frontal cortex (motor cortex) http://purl.obolibrary.org/obo/UBERON_0001384 primary motor cortex http://purl.obolibrary.org/obo/UBERON_0013696 tonsil epithelium http://purl.obolibrary.org/obo/UBERON_0003351 pharyngeal epithelium The epithelium that forms the surface of the tonsil dips into the underlying connective tissue in numerous places, forming crypts kown as tonsillar crypts. Stratified squamous epithelium, that may be heavily infiltrated by lymphocytes. Epithelial cells are present in the germinal as well as in the periphery of the nodule. https://purl.brain-bican.org/ontology/mbao/MBA_35 Oculomotor nucleus http://purl.obolibrary.org/obo/UBERON_0001715 oculomotor nuclear complex https://purl.brain-bican.org/ontology/dhbao/DHBA_12198 oculomotor nucleus https://purl.brain-bican.org/ontology/dhbao/DHBA_10649 gray matter of midbrain http://purl.obolibrary.org/obo/UBERON_0013697 exocrine pancreas epithelium http://purl.obolibrary.org/obo/UBERON_0000483 epithelium Epithelium lining the exocrine pancreas. https://purl.brain-bican.org/ontology/dhbao/DHBA_10161 frontal neocortex https://purl.brain-bican.org/ontology/dhbao/DHBA_10157 gray matter of forebrain http://purl.obolibrary.org/obo/UBERON_0013699 strand of axillary hair http://purl.obolibrary.org/obo/UBERON_0001037 strand of hair A strand of hair that is part of a axilla. http://purl.obolibrary.org/obo/UBERON_0013700 axial musculature http://purl.obolibrary.org/obo/UBERON_0001015 musculature Musculature of the head and neck, spine, and ribs. https://purl.brain-bican.org/ontology/dhbao/DHBA_10334 caudate nucleus http://purl.obolibrary.org/obo/UBERON_0001873 caudate nucleus https://purl.brain-bican.org/ontology/dhbao/DHBA_10338 putamen http://purl.obolibrary.org/obo/UBERON_0001874 putamen http://purl.obolibrary.org/obo/UBERON_0013701 main body axis http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision A principle subdivision of an organism that includes all structures along the primary axis, typically the anterior-posterior axis, from head to tail, including structures of the body proper where present (for example, ribs), but excluding appendages. https://purl.brain-bican.org/ontology/dhbao/DHBA_10342 globus pallidus http://purl.obolibrary.org/obo/UBERON_0001875 globus pallidus http://purl.obolibrary.org/obo/UBERON_0013702 body proper http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision The region of the organism associated with the visceral organs. https://purl.brain-bican.org/ontology/dhbao/DHBA_10361 amygdaloid complex https://purl.brain-bican.org/ontology/dhbao/DHBA_10332 basal nuclei (basal ganglia) http://purl.obolibrary.org/obo/UBERON_0013703 integumentary projection http://purl.obolibrary.org/obo/UBERON_0006003 integumentary adnexa Anatomical projection that is part of the integumentl system. https://purl.brain-bican.org/ontology/mbao/MBA_564 Medial septal nucleus http://purl.obolibrary.org/obo/UBERON_0001877 medial septal nucleus http://purl.obolibrary.org/obo/UBERON_0013704 notochordal canal http://purl.obolibrary.org/obo/UBERON_0004111 anatomical conduit A tubular passage that extends from the primitive pit into the head process during the early stages of embryonic development in mammals. It perforates the splanchnopleure layer so that the yolk sac and the amnion are connected temporarily. https://purl.brain-bican.org/ontology/dhbao/DHBA_10351 medial septal nucleus http://purl.obolibrary.org/obo/UBERON_0001877 medial septal nucleus https://purl.brain-bican.org/ontology/mbao/MBA_596 Diagonal band nucleus http://purl.obolibrary.org/obo/UBERON_0001879 nucleus of diagonal band http://purl.obolibrary.org/obo/UBERON_0013727 notochordal fluid http://purl.obolibrary.org/obo/UBERON_0006314 bodily fluid Fluid contained within the notochordal canal. https://purl.brain-bican.org/ontology/dhbao/DHBA_10354 nucleus of diagonal band http://purl.obolibrary.org/obo/UBERON_0001879 nucleus of diagonal band https://purl.brain-bican.org/ontology/mbao/MBA_481 Islands of Calleja http://purl.obolibrary.org/obo/UBERON_0001881 island of Calleja http://purl.obolibrary.org/obo/UBERON_0013739 base of crypt of Lieberkuhn http://purl.obolibrary.org/obo/UBERON_0011184 epithelium of crypt of Lieberkuhn The basal portion (further from lumen) of an intestinal crypt. Contains multipotent stem cells. Stem cells in the crypts divide to form daughter cells. One daughter cell from each stem cell division is retained as a stem cell. The other becomes committed to differentiate along one of four pathways to become an enterocyte, enteroendocrine cell, goblet cell or Paneth cell. https://purl.brain-bican.org/ontology/dhbao/DHBA_10358 islands of Calleja http://purl.obolibrary.org/obo/UBERON_0001881 island of Calleja https://purl.brain-bican.org/ontology/mbao/MBA_56 Nucleus accumbens http://purl.obolibrary.org/obo/UBERON_0001882 nucleus accumbens https://purl.brain-bican.org/ontology/dhbao/DHBA_10339 nucleus accumbens http://purl.obolibrary.org/obo/UBERON_0001882 nucleus accumbens http://purl.obolibrary.org/obo/UBERON_0013740 wall of crypt of Lieberkuhn http://purl.obolibrary.org/obo/UBERON_0011184 epithelium of crypt of Lieberkuhn The lateral parts of an intestinal crypt, continuous distally with the base and proximally with the intestinal villus epithelium. http://purl.obolibrary.org/obo/UBERON_0013741 base of crypt of Lieberkuhn of large intestine http://purl.obolibrary.org/obo/UBERON_0013739 base of crypt of Lieberkuhn A base of crypt of Lieberkuhn that is part of a large intestine. https://purl.brain-bican.org/ontology/mbao/MBA_754 Olfactory tubercle http://purl.obolibrary.org/obo/UBERON_0001883 olfactory tubercle https://purl.brain-bican.org/ontology/dhbao/DHBA_10310 olfactory tubercle http://purl.obolibrary.org/obo/UBERON_0001883 olfactory tubercle http://purl.obolibrary.org/obo/UBERON_0013742 wall of crypt of Lieberkuhn of large intestine http://purl.obolibrary.org/obo/UBERON_0013740 wall of crypt of Lieberkuhn A wall of crypt of Lieberkuhn that is part of a large intestine. https://purl.brain-bican.org/ontology/mbao/MBA_726 Dentate gyrus https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions http://purl.obolibrary.org/obo/UBERON_0013743 base of crypt of Lieberkuhn of small intestine http://purl.obolibrary.org/obo/UBERON_0013739 base of crypt of Lieberkuhn The basal portion (further from lumen) of a intestinal crypt that is located in the small intestine. https://purl.brain-bican.org/ontology/mbao/MBA_665 lateral olfactory tract, body https://purl.brain-bican.org/ontology/mbao/MBA_1009 fiber tracts http://purl.obolibrary.org/obo/UBERON_0013744 wall of crypt of Lieberkuhn of small intestine http://purl.obolibrary.org/obo/UBERON_0013740 wall of crypt of Lieberkuhn The lateral parts of an intestinal crypt that is located in the small intestine, continuous distally with the base and proximally with the intestinal villus epithelium. https://purl.brain-bican.org/ontology/dhbao/DHBA_12075 lateral olfactory stria https://purl.brain-bican.org/ontology/dhbao/DHBA_12073 olfactory tract https://purl.brain-bican.org/ontology/dhbao/DHBA_10156 forebrain (prosencephalon) http://purl.obolibrary.org/obo/UBERON_0001890 forebrain http://purl.obolibrary.org/obo/UBERON_0013749 metaphysis of humerus http://purl.obolibrary.org/obo/UBERON_0001438 metaphysis A metaphysis that is part of a metaphysis. http://purl.obolibrary.org/obo/UBERON_0013750 metaphysis of tibia http://purl.obolibrary.org/obo/UBERON_0001438 metaphysis A metaphysis that is part of a tibia. https://purl.brain-bican.org/ontology/mbao/MBA_313 Midbrain https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions https://purl.brain-bican.org/ontology/dhbao/DHBA_10648 midbrain (mesencephalon) http://purl.obolibrary.org/obo/UBERON_0001891 midbrain http://purl.obolibrary.org/obo/UBERON_0013752 diaphysis of metacarpal bone http://purl.obolibrary.org/obo/UBERON_0004769 diaphysis A diaphysis that is part of a metacarpal bone. https://purl.brain-bican.org/ontology/dhbao/DHBA_12664 hindbrain neuromeres http://purl.obolibrary.org/obo/UBERON_0004733 segmental subdivision of hindbrain http://purl.obolibrary.org/obo/UBERON_0013754 integumentary system layer http://purl.obolibrary.org/obo/UBERON_0004923 organ component layer An organ component layer that is part of a integumental system. https://purl.brain-bican.org/ontology/dhbao/DHBA_10655 metencephalon http://purl.obolibrary.org/obo/UBERON_0004731 neuromere http://purl.obolibrary.org/obo/UBERON_0013755 arterial blood http://purl.obolibrary.org/obo/UBERON_0000178 blood A blood that is part of a artery. http://purl.obolibrary.org/obo/UBERON_0013756 venous blood http://purl.obolibrary.org/obo/UBERON_0000178 blood A blood that is part of a vein. https://purl.brain-bican.org/ontology/mbao/MBA_354 Medulla http://purl.obolibrary.org/obo/UBERON_0001896 medulla oblongata https://purl.brain-bican.org/ontology/mbao/MBA_549 Thalamus https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions http://purl.obolibrary.org/obo/UBERON_0013757 capillary blood http://purl.obolibrary.org/obo/UBERON_0000178 blood A blood that is part of a capillary. https://purl.brain-bican.org/ontology/dhbao/DHBA_10390 thalamus http://purl.obolibrary.org/obo/UBERON_0001897 dorsal plus ventral thalamus http://purl.obolibrary.org/obo/UBERON_0013758 cervical os http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure One of two openings in the uterine cervix. https://purl.brain-bican.org/ontology/mbao/MBA_1097 Hypothalamus https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions http://purl.obolibrary.org/obo/UBERON_0013760 external cervical os http://purl.obolibrary.org/obo/UBERON_0013758 cervical os Opening of uterine cervix into the vagina. http://purl.obolibrary.org/obo/UBERON_0013761 cervical cavity http://purl.obolibrary.org/obo/UBERON_0002553 anatomical cavity The cavity formed by the walls of the cervix. https://purl.brain-bican.org/ontology/dhbao/DHBA_10467 hypothalamus http://purl.obolibrary.org/obo/UBERON_0001898 hypothalamus https://purl.brain-bican.org/ontology/mbao/MBA_958 Epithalamus https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions http://purl.obolibrary.org/obo/UBERON_0013765 digestive system element http://purl.obolibrary.org/obo/UBERON_0000062 organ Any of the organs or elements that are part of the digestive system. Examples: tongue, esophagus, spleen, crop, lunge feeding organ, tooth elements. https://purl.brain-bican.org/ontology/dhbao/DHBA_10451 epithalamus http://purl.obolibrary.org/obo/UBERON_0001899 epithalamus http://purl.obolibrary.org/obo/UBERON_0013768 great vessel of heart http://purl.obolibrary.org/obo/UBERON_0001981 blood vessel Great vessels is a term used to refer collectively to the large vessels that bring blood to and from the heart. https://purl.brain-bican.org/ontology/dhbao/DHBA_10461 ventral thalamus http://purl.obolibrary.org/obo/UBERON_0001900 ventral thalamus http://purl.obolibrary.org/obo/UBERON_0013769 uterine lumen http://purl.obolibrary.org/obo/UBERON_0002558 organ cavity An organ cavity that is part of a uterus. https://purl.brain-bican.org/ontology/mbao/MBA_470 Subthalamic nucleus http://purl.obolibrary.org/obo/UBERON_0006568 hypothalamic nucleus http://purl.obolibrary.org/obo/UBERON_0013772 left nipple http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure A nipple that is in_the_left_side_of a body proper. https://purl.brain-bican.org/ontology/dhbao/DHBA_10466 subthalamic nucleus http://purl.obolibrary.org/obo/UBERON_0001906 subthalamic nucleus http://purl.obolibrary.org/obo/UBERON_0013773 right nipple http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure A nipple that is in_the_right_side_of a body proper. https://purl.brain-bican.org/ontology/mbao/MBA_797 Zona incerta http://purl.obolibrary.org/obo/UBERON_0006568 hypothalamic nucleus http://purl.obolibrary.org/obo/UBERON_0013774 diaphysis of metatarsal bone http://purl.obolibrary.org/obo/UBERON_0004769 diaphysis A diaphysis that is part of a metatarsal bone. https://purl.brain-bican.org/ontology/dhbao/DHBA_10463 zona incerta http://purl.obolibrary.org/obo/UBERON_0001907 zona incerta https://purl.brain-bican.org/ontology/dhbao/DHBA_10429 lateral geniculate nucleus https://purl.brain-bican.org/ontology/dhbao/DHBA_10440 posterior nucleus of thalamus http://purl.obolibrary.org/obo/UBERON_0013776 skin of palmar/plantar part of autopod http://purl.obolibrary.org/obo/UBERON_0015790 autopod skin A zone of skin that is part of a palmar/plantar part of autopod. https://purl.brain-bican.org/ontology/mbao/MBA_38 Paraventricular hypothalamic nucleus http://purl.obolibrary.org/obo/UBERON_0006331 brainstem nucleus http://purl.obolibrary.org/obo/UBERON_0013778 skin of sole of pes http://purl.obolibrary.org/obo/UBERON_0013776 skin of palmar/plantar part of autopod A zone of skin that is part of a skin of pes. https://purl.brain-bican.org/ontology/dhbao/DHBA_10476 paraventricular nucleus of hypothalamus http://purl.obolibrary.org/obo/UBERON_0001930 paraventricular nucleus of hypothalamus http://purl.obolibrary.org/obo/UBERON_0014283 piriform cortex layer 3 http://purl.obolibrary.org/obo/UBERON_0022303 nervous system cell part layer Deepest of 3 cytoarchitecturally defined layers of the piriform cortex characterized by a moderately high density of pyramidal cells and large numbers of basal dendrites descending from pyramidal cells in layer 2. https://purl.brain-bican.org/ontology/mbao/MBA_223 Arcuate hypothalamic nucleus http://purl.obolibrary.org/obo/UBERON_0006331 brainstem nucleus https://purl.brain-bican.org/ontology/dhbao/DHBA_10492 arcuate nucleus of hypothalamus http://purl.obolibrary.org/obo/UBERON_0001932 arcuate nucleus of hypothalamus http://purl.obolibrary.org/obo/UBERON_0014371 future telencephalon http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure Embryonic structure that gives rise to the telencephalon. https://purl.brain-bican.org/ontology/dhbao/DHBA_12195 midbrain tegmentum http://purl.obolibrary.org/obo/UBERON_0001943 midbrain tegmentum http://purl.obolibrary.org/obo/UBERON_0014382 collection of hairs on head or neck http://purl.obolibrary.org/obo/UBERON_0010164 collection of hairs A collection of hairs that is part of a craniocervical region. http://purl.obolibrary.org/obo/UBERON_0014387 mesenchyme derived from neural crest http://purl.obolibrary.org/obo/UBERON_0010313 neural crest-derived structure Mesenchyme that develops_from the neural crest[Automatically generated definition]. https://purl.brain-bican.org/ontology/mbao/MBA_1100 Pretectal region http://purl.obolibrary.org/obo/UBERON_0019267 gray matter of midbrain https://purl.brain-bican.org/ontology/dhbao/DHBA_12181 pretectal region https://purl.brain-bican.org/ontology/dhbao/DHBA_10649 gray matter of midbrain http://purl.obolibrary.org/obo/UBERON_0014388 kidney collecting duct epithelium http://purl.obolibrary.org/obo/UBERON_0004211 nephron epithelium The simple cuboidal epithelium lining the lumen of kidney collecting ducts. https://purl.brain-bican.org/ontology/mbao/MBA_315 Isocortex https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions http://purl.obolibrary.org/obo/UBERON_0014389 gustatory papilla of tongue http://purl.obolibrary.org/obo/UBERON_0001726 papilla of tongue A papilla that contain taste buds, including the fungiform, foliate, and circumvallate papillae. https://purl.brain-bican.org/ontology/dhbao/DHBA_10160 neocortex (isocortex) http://purl.obolibrary.org/obo/UBERON_0001950 neocortex http://purl.obolibrary.org/obo/UBERON_0014390 muscle layer of ileum http://purl.obolibrary.org/obo/UBERON_0011201 muscle layer of small intestine A muscular coat that is part of a ileum. https://purl.brain-bican.org/ontology/mbao/MBA_375 Ammon's horn https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions https://purl.brain-bican.org/ontology/dhbao/DHBA_10296 hippocampal proper http://purl.obolibrary.org/obo/UBERON_0001954 Ammon's horn http://purl.obolibrary.org/obo/UBERON_0014391 palmar/plantar sweat gland http://purl.obolibrary.org/obo/UBERON_0000423 eccrine sweat gland A sweat gland that is part of the skin of the palmar part of the manus or plantar part of the pes. http://purl.obolibrary.org/obo/UBERON_0036269 penis blood vessel http://purl.obolibrary.org/obo/UBERON_0001981 blood vessel http://purl.obolibrary.org/obo/UBERON_0014392 sweat of palm http://purl.obolibrary.org/obo/UBERON_0001089 sweat Sweat that is produced by the glands on the palmar and plantar surfaces. https://purl.brain-bican.org/ontology/mbao/MBA_1065 Hindbrain https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions http://purl.obolibrary.org/obo/UBERON_0014393 sweat of axilla http://purl.obolibrary.org/obo/UBERON_0001089 sweat Sweat that is produced by the glands of the axilla. https://purl.brain-bican.org/ontology/dhbao/DHBA_10653 hindbrain (rhombencephalon) http://purl.obolibrary.org/obo/UBERON_0002028 hindbrain http://purl.obolibrary.org/obo/UBERON_0014395 proximal mesopodial bone http://purl.obolibrary.org/obo/UBERON_0017750 proximal mesopodial endochondral element A proximal mesopodial endochondral element that is composed primarily of a bone tissue. https://purl.brain-bican.org/ontology/mbao/MBA_286 Suprachiasmatic nucleus http://purl.obolibrary.org/obo/UBERON_0006331 brainstem nucleus https://purl.brain-bican.org/ontology/dhbao/DHBA_10480 suprachiasmatic nucleus http://purl.obolibrary.org/obo/UBERON_0002034 suprachiasmatic nucleus http://purl.obolibrary.org/obo/UBERON_0014398 respiratory muscle http://purl.obolibrary.org/obo/UBERON_0003831 respiratory system muscle Muscle that is part of the respiratory system. https://purl.brain-bican.org/ontology/dhbao/DHBA_12251 substantia nigra http://purl.obolibrary.org/obo/UBERON_0007414 nucleus of midbrain tegmentum http://purl.obolibrary.org/obo/UBERON_0014399 sinusoidal space http://purl.obolibrary.org/obo/UBERON_0010161 lumen of blood vessel An anatomical space that is enclosed by a sinusoid. https://purl.brain-bican.org/ontology/mbao/MBA_238 Nucleus raphe pontis http://purl.obolibrary.org/obo/UBERON_0002047 pontine raphe nucleus http://purl.obolibrary.org/obo/UBERON_0014400 hepatic sinusoidal space http://purl.obolibrary.org/obo/UBERON_0014399 sinusoidal space A sinusoidal space that is part of a hepatic sinusoid. http://purl.obolibrary.org/obo/UBERON_0014401 renal venous blood vessel http://purl.obolibrary.org/obo/UBERON_0003920 venous blood vessel Any member of the network of tubes that return blood from the renal tissues to the systemic circulation. https://purl.brain-bican.org/ontology/dhbao/DHBA_12475 raphe pontis nucleus http://purl.obolibrary.org/obo/UBERON_0002047 pontine raphe nucleus http://purl.obolibrary.org/obo/UBERON_0014402 sex-specific anatomical structure http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure A part of the body present only in a specific gender. http://purl.obolibrary.org/obo/UBERON_0036302 vasculature of central nervous system plus retina http://purl.obolibrary.org/obo/UBERON_0002049 vasculature http://purl.obolibrary.org/obo/UBERON_0014403 male anatomical structure http://purl.obolibrary.org/obo/UBERON_0014402 sex-specific anatomical structure A part of the body present only in males. https://purl.brain-bican.org/ontology/dhbao/DHBA_10508 marginal zone http://purl.obolibrary.org/obo/UBERON_0010403 brain marginal zone https://purl.brain-bican.org/ontology/dhbao/DHBA_10522 subplate zone http://purl.obolibrary.org/obo/UBERON_0004035 cortical subplate http://purl.obolibrary.org/obo/UBERON_0014404 female anatomical structure http://purl.obolibrary.org/obo/UBERON_0014402 sex-specific anatomical structure A part of the body present only in females. https://purl.brain-bican.org/ontology/mbao/MBA_398 Superior olivary complex http://purl.obolibrary.org/obo/UBERON_0002128 superior olivary complex http://purl.obolibrary.org/obo/UBERON_0014450 pretectal nucleus http://purl.obolibrary.org/obo/UBERON_0002308 nucleus of brain A neural nucleus of the pretectal area (between dorsal thalamus and optic tectum) that receives afferents primarily from the retina and the optic tectum and are involved in modulating motor behavior in response to visual input. https://purl.brain-bican.org/ontology/dhbao/DHBA_12462 superior olivary complex https://purl.brain-bican.org/ontology/dhbao/DHBA_10654 gray matter of the hindbrain https://purl.brain-bican.org/ontology/mbao/MBA_528 Cerebellar cortex http://purl.obolibrary.org/obo/UBERON_0002129 cerebellar cortex http://purl.obolibrary.org/obo/UBERON_0014451 tongue taste bud http://purl.obolibrary.org/obo/UBERON_0013765 digestive system element A taste bud that is located on the tongue, situated on a gustatory papilla. http://purl.obolibrary.org/obo/UBERON_0014452 gustatory epithelium of tongue http://purl.obolibrary.org/obo/UBERON_0003357 epithelium of tongue A gustatory epithelium that is part of a tongue. https://purl.brain-bican.org/ontology/dhbao/DHBA_10657 cerebellar cortex https://purl.brain-bican.org/ontology/dhbao/DHBA_10654 gray matter of the hindbrain https://purl.brain-bican.org/ontology/mbao/MBA_519 Cerebellar nuclei http://purl.obolibrary.org/obo/UBERON_0002130 cerebellar nuclear complex http://purl.obolibrary.org/obo/UBERON_0014453 gustatory epithelium of palate http://purl.obolibrary.org/obo/UBERON_0002926 gustatory epithelium A gustatory epithelium that is part of a roof of mouth. https://purl.brain-bican.org/ontology/dhbao/DHBA_10660 cerebellar deep nuclei https://purl.brain-bican.org/ontology/dhbao/DHBA_10654 gray matter of the hindbrain http://purl.obolibrary.org/obo/UBERON_0014454 visceral abdominal adipose tissue http://purl.obolibrary.org/obo/UBERON_0007808 adipose tissue of abdominal region Subcutaneous adipose tissue that is located in the peritoneal cavity. https://purl.brain-bican.org/ontology/mbao/MBA_599626923 Subcommissural organ https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions http://purl.obolibrary.org/obo/UBERON_0014455 subcutaneous abdominal adipose tissue http://purl.obolibrary.org/obo/UBERON_0007808 adipose tissue of abdominal region Subcutaneous adipose tissue that is located in the abdominal region. https://purl.brain-bican.org/ontology/dhbao/DHBA_12101 subcommissural organ http://purl.obolibrary.org/obo/UBERON_0002139 subcommissural organ http://purl.obolibrary.org/obo/UBERON_0014463 cardiac ganglion http://purl.obolibrary.org/obo/UBERON_0001808 parasympathetic ganglion Any of the parasympathetic ganglia of the cardiac plexus between the arch of the aorta and the bifurcation of the pulmonary artery. https://purl.brain-bican.org/ontology/mbao/MBA_1052 Pedunculopontine nucleus https://purl.brain-bican.org/ontology/mbao/MBA_128 Midbrain reticular nucleus https://purl.brain-bican.org/ontology/dhbao/DHBA_12413 peduncular nucleus http://purl.obolibrary.org/obo/UBERON_0009662 hindbrain nucleus http://purl.obolibrary.org/obo/UBERON_0014477 thoracic skeleton http://purl.obolibrary.org/obo/UBERON_0010912 subdivision of skeleton Subdivision of skeletal system that consists of all skeletal elements in the thoracic region of the trunk. In most vertebrates this is the rib cage and sternum. https://purl.brain-bican.org/ontology/mbao/MBA_147 Locus ceruleus https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions http://purl.obolibrary.org/obo/UBERON_0014478 rib skeletal system http://purl.obolibrary.org/obo/UBERON_0000075 subdivision of skeletal system Subdivision of skeletal system that consists of all ribs and rib joints in an organism. In many vertebrates this consists of the combination of the rib cage and all rib joints, but some vertebrates have ribs outside the thoracic rib cage. https://purl.brain-bican.org/ontology/dhbao/DHBA_12819 locus coeruleus http://purl.obolibrary.org/obo/UBERON_0002148 locus ceruleus http://purl.obolibrary.org/obo/UBERON_0014538 subdivision of spinal cord central canal http://purl.obolibrary.org/obo/UBERON_0004111 anatomical conduit A subdivision of the central canal of the spinal cord along its anterior-posterior axis. This is typically subdivided into cervical, thoracic, lumbar and sacral segments. https://purl.brain-bican.org/ontology/mbao/MBA_462 Superior salivatory nucleus http://purl.obolibrary.org/obo/UBERON_0002149 superior salivatory nucleus https://purl.brain-bican.org/ontology/dhbao/DHBA_12435 superior salivatory nucleus http://purl.obolibrary.org/obo/UBERON_0002149 superior salivatory nucleus https://purl.brain-bican.org/ontology/mbao/MBA_931 Pontine gray http://purl.obolibrary.org/obo/UBERON_0002151 pontine nuclear group http://purl.obolibrary.org/obo/UBERON_0014540 white matter lamina of cerebellum http://purl.obolibrary.org/obo/UBERON_0014530 white matter lamina of neuraxis The white laminae of cerebellum is subdivision of the cerebellar cortex comprised of myelinated axons lying deep to the granule cell layer of the cerebellar cortex. https://purl.brain-bican.org/ontology/dhbao/DHBA_12406 pontine nucleus http://purl.obolibrary.org/obo/UBERON_0002151 pontine nuclear group http://purl.obolibrary.org/obo/UBERON_0014541 thoracic division of spinal cord central canal http://purl.obolibrary.org/obo/UBERON_0014538 subdivision of spinal cord central canal Part of spinal cord central canal contained in the thoracic spinal cord. It is continuous rostrally with the cervical spinal cord central canal and caudally with the lumbar spinal cord central canal. https://purl.brain-bican.org/ontology/mbao/MBA_78 middle cerebellar peduncle https://purl.brain-bican.org/ontology/mbao/MBA_752 cerebellar peduncles http://purl.obolibrary.org/obo/UBERON_0014542 cervical division of cord spinal central canal http://purl.obolibrary.org/obo/UBERON_0014538 subdivision of spinal cord central canal Part of central canal contained within the cervical spinal cord. It is continuous caudally with the thoracic spinal cord central canal and rostrally with the fourth ventricle of the brain via the obex. https://purl.brain-bican.org/ontology/dhbao/DHBA_12768 middle cerebellar peduncle https://purl.brain-bican.org/ontology/dhbao/DHBA_10668 white matter of hindbrain https://purl.brain-bican.org/ontology/mbao/MBA_207 Area postrema https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions http://purl.obolibrary.org/obo/UBERON_0014543 lumbar division of spinal cord central canal http://purl.obolibrary.org/obo/UBERON_0014538 subdivision of spinal cord central canal Part of central canal lying within the lumbar spinal cord. It is continuous rostrally with the central canal of the thoracic spinal cord and caudally with the central canal of the sacral spinal cord. https://purl.brain-bican.org/ontology/dhbao/DHBA_12807 area postrema http://purl.obolibrary.org/obo/UBERON_0002162 area postrema http://purl.obolibrary.org/obo/UBERON_0014547 sacral division of spinal cord central canal http://purl.obolibrary.org/obo/UBERON_0014538 subdivision of spinal cord central canal Part of spinal cord central canal contained in the sacral spinal cord. It is continuous rostrally with the spinal cord central canal of the lumbar cord. https://purl.brain-bican.org/ontology/mbao/MBA_502 Subiculum https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions http://purl.obolibrary.org/obo/UBERON_0014550 pyramidal layer of CA3 http://purl.obolibrary.org/obo/UBERON_0035788 layer of CA3 field A layer of hippocampal field that is part of a hippocampus pyramidal layer and is part of a CA3 field of hippocampus. https://purl.brain-bican.org/ontology/dhbao/DHBA_10302 subiculum http://purl.obolibrary.org/obo/UBERON_0002191 subiculum https://purl.brain-bican.org/ontology/mbao/MBA_10671 Median eminence https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions http://purl.obolibrary.org/obo/UBERON_0014553 CA3 stratum oriens http://purl.obolibrary.org/obo/UBERON_0035788 layer of CA3 field Part of stratum oriens lying in area CA3 deep to the CA3 pyramidal cell layer and continuous with stratum oriens of area CA2 and bounded by the dentate gyrus hilus. https://purl.brain-bican.org/ontology/dhbao/DHBA_13338 median eminence http://purl.obolibrary.org/obo/UBERON_0002197 median eminence of neurohypophysis http://purl.obolibrary.org/obo/UBERON_0014556 CA3 stratum radiatum http://purl.obolibrary.org/obo/UBERON_0035788 layer of CA3 field Part of stratum radiatum in area CA3, lying superficial to the stratum lucidum and deep to CA3 stratum lacunosum-moleculare. https://purl.brain-bican.org/ontology/mbao/MBA_108 choroid plexus http://purl.obolibrary.org/obo/UBERON_0002307 choroid plexus of lateral ventricle http://purl.obolibrary.org/obo/UBERON_0014571 CA3 alveus http://purl.obolibrary.org/obo/UBERON_0035788 layer of CA3 field Part of alveus lying within hippocampal sector CA3. https://purl.brain-bican.org/ontology/dhbao/DHBA_10601 choroid plexus of lateral ventricle http://purl.obolibrary.org/obo/UBERON_0002307 choroid plexus of lateral ventricle http://purl.obolibrary.org/obo/UBERON_0014609 thoracic spinal cord dorsal horn http://purl.obolibrary.org/obo/UBERON_0002256 dorsal horn of spinal cord A dorsal horn of spinal cord that is part of a thoracic spinal cord. https://purl.brain-bican.org/ontology/dhbao/DHBA_12808 choroid plexus of the fourth ventricle http://purl.obolibrary.org/obo/UBERON_0002290 choroid plexus of fourth ventricle http://purl.obolibrary.org/obo/UBERON_0014610 thoracic spinal cord ventral horn http://purl.obolibrary.org/obo/UBERON_0002257 ventral horn of spinal cord A ventral horn of spinal cord that is part of a thoracic spinal cord. https://purl.brain-bican.org/ontology/mbao/MBA_331 Mammillary body http://purl.obolibrary.org/obo/UBERON_0002206 mammillary body http://purl.obolibrary.org/obo/UBERON_0014613 cervical spinal cord gray matter http://purl.obolibrary.org/obo/UBERON_0002315 gray matter of spinal cord A gray matter of spinal cord that is part of a cervical spinal cord. https://purl.brain-bican.org/ontology/dhbao/DHBA_15546 mammillary body http://purl.obolibrary.org/obo/UBERON_0002206 mammillary body https://purl.brain-bican.org/ontology/mbao/MBA_338 Subfornical organ https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions http://purl.obolibrary.org/obo/UBERON_0014614 cervical spinal cord white matter http://purl.obolibrary.org/obo/UBERON_0002318 white matter of spinal cord A white matter of spinal cord that is part of a cervical spinal cord. https://purl.brain-bican.org/ontology/dhbao/DHBA_12104 subfornical organ http://purl.obolibrary.org/obo/UBERON_0002219 subfornical organ http://purl.obolibrary.org/obo/UBERON_0014615 accessory nerve root http://purl.obolibrary.org/obo/UBERON_0002211 nerve root A nerve root that is part of a accessory XI nerve. https://purl.brain-bican.org/ontology/mbao/MBA_1073 Hemispheric regions https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions http://purl.obolibrary.org/obo/UBERON_0014620 cervical spinal cord dorsal horn http://purl.obolibrary.org/obo/UBERON_0002256 dorsal horn of spinal cord A dorsal horn of spinal cord that is part of a cervical spinal cord. https://purl.brain-bican.org/ontology/dhbao/DHBA_10659 cerebellar hemisphere http://purl.obolibrary.org/obo/UBERON_0002245 cerebellar hemisphere http://purl.obolibrary.org/obo/UBERON_0014621 cervical spinal cord ventral horn http://purl.obolibrary.org/obo/UBERON_0002257 ventral horn of spinal cord A ventral horn of spinal cord that is part of a cervical spinal cord. https://purl.brain-bican.org/ontology/dhbao/DHBA_10307 olfactory bulb http://purl.obolibrary.org/obo/UBERON_0002264 olfactory bulb http://purl.obolibrary.org/obo/UBERON_0014635 dorsal nerve root of cervical spinal cord http://purl.obolibrary.org/obo/UBERON_0009632 root of cervical nerve A dorsal root of spinal cord that overlaps a cervical spinal cord. https://purl.brain-bican.org/ontology/dhbao/DHBA_12073 olfactory tract http://purl.obolibrary.org/obo/UBERON_0002265 olfactory tract https://purl.brain-bican.org/ontology/mbao/MBA_159 Anterior olfactory nucleus http://purl.obolibrary.org/obo/UBERON_0002266 anterior olfactory nucleus http://purl.obolibrary.org/obo/UBERON_0014636 thoracic spinal cord gray matter http://purl.obolibrary.org/obo/UBERON_0002315 gray matter of spinal cord A gray matter of spinal cord that is part of a thoracic spinal cord. https://purl.brain-bican.org/ontology/dhbao/DHBA_10308 anterior olfactory nucleus http://purl.obolibrary.org/obo/UBERON_0002266 anterior olfactory nucleus http://purl.obolibrary.org/obo/UBERON_0014637 thoracic spinal cord white matter http://purl.obolibrary.org/obo/UBERON_0002318 white matter of spinal cord A white matter of spinal cord that is part of a thoracic spinal cord. https://purl.brain-bican.org/ontology/mbao/MBA_157 Periventricular zone http://purl.obolibrary.org/obo/UBERON_0002271 periventricular zone of hypothalamus http://purl.obolibrary.org/obo/UBERON_0014638 lumbar spinal cord dorsal horn http://purl.obolibrary.org/obo/UBERON_0002256 dorsal horn of spinal cord A dorsal horn of spinal cord that is part of a lumbar spinal cord. http://purl.obolibrary.org/obo/UBERON_0014639 frontal sulcus http://purl.obolibrary.org/obo/UBERON_0013118 sulcus of brain A sulcus of brain that is part of a frontal cortex. https://purl.brain-bican.org/ontology/mbao/MBA_290 Hypothalamic lateral zone http://purl.obolibrary.org/obo/UBERON_0002273 lateral zone of hypothalamus https://purl.brain-bican.org/ontology/mbao/MBA_164 central canal, spinal cord/medulla http://purl.obolibrary.org/obo/UBERON_0002291 central canal of spinal cord http://purl.obolibrary.org/obo/UBERON_0014642 vestibulocerebellum http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain A phylogenetic subdivision of the cerebellum, the oldest part, which regulates balance and eye movements. It receives vestibular input from both the semicircular canals and from the vestibular nuclei, and sends fibres back to the medial and lateral vestibular nuclei. It also receives visual input from the superior colliculi and from the visual cortex (the latter via the pontine nuclei, forming a cortico-ponto-cerebellar pathway). Lesions of the vestibulocerebellum cause disturbances of balance and gait. https://purl.brain-bican.org/ontology/dhbao/DHBA_146035108 ventricle of spinal cord http://purl.obolibrary.org/obo/UBERON_0002291 central canal of spinal cord https://purl.brain-bican.org/ontology/mbao/MBA_603 fimbria http://purl.obolibrary.org/obo/UBERON_0002310 hippocampus fimbria http://purl.obolibrary.org/obo/UBERON_0014649 white matter of medulla oblongata http://purl.obolibrary.org/obo/UBERON_0019262 white matter of myelencephalon A white matter that is part of a medulla oblongata. https://purl.brain-bican.org/ontology/dhbao/DHBA_10575 fimbria http://purl.obolibrary.org/obo/UBERON_0002310 hippocampus fimbria https://purl.brain-bican.org/ontology/dhbao/DHBA_12291 midbrain tectum http://purl.obolibrary.org/obo/UBERON_0002314 midbrain tectum http://purl.obolibrary.org/obo/UBERON_0014686 angular vein http://purl.obolibrary.org/obo/UBERON_0009141 craniocervical region vein The angular vein formed by the junction of the frontal vein and supraorbital vein, runs obliquely downward, on the side of the root of the nose, to the level of the lower margin of the orbit, where it becomes the anterior facial vein. It receives the external nasal veins of the ala nasi, and communicates with the superior ophthalmic vein through the nasofrontal vein, thus establishing an important anastomosis between the anterior facial vein and the cavernous sinus. https://purl.brain-bican.org/ontology/dhbao/DHBA_146035048 gray matter of spinal cord http://purl.obolibrary.org/obo/UBERON_0002315 gray matter of spinal cord https://purl.brain-bican.org/ontology/dhbao/DHBA_146035088 white matter of spinal cord http://purl.obolibrary.org/obo/UBERON_0002318 white matter of spinal cord http://purl.obolibrary.org/obo/UBERON_0014687 temporal sulcus http://purl.obolibrary.org/obo/UBERON_0013118 sulcus of brain Any of three grooves in the temporal lobe including the inferior, middle, and superior temporal sulci. https://purl.brain-bican.org/ontology/mbao/MBA_1089 Hippocampal formation https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions https://purl.brain-bican.org/ontology/dhbao/DHBA_10294 hippocampus (hippocampal formation) http://purl.obolibrary.org/obo/UBERON_0002421 hippocampal formation http://purl.obolibrary.org/obo/UBERON_0014695 deep auricular artery http://purl.obolibrary.org/obo/UBERON_0009655 auricular artery The deep auricular artery often arises in common with the anterior tympanic artery. It ascends in the substance of the parotid gland, behind the temporomandibular articulation, pierces the cartilaginous or bony wall of the external acoustic meatus, and supplies its cuticular lining and the outer surface of the tympanic membrane. It gives a branch to the temporomandibular joint. https://purl.brain-bican.org/ontology/mbao/MBA_145 fourth ventricle http://purl.obolibrary.org/obo/UBERON_0002422 fourth ventricle https://purl.brain-bican.org/ontology/dhbao/DHBA_12805 fourth ventricle http://purl.obolibrary.org/obo/UBERON_0002422 fourth ventricle http://purl.obolibrary.org/obo/UBERON_0014699 extraembryonic venous system http://purl.obolibrary.org/obo/UBERON_0014701 extraembryonic vascular system A venous system that overlaps a umbilical cord and is part of a entire extraembryonic component. https://purl.brain-bican.org/ontology/mbao/MBA_477 Striatum http://purl.obolibrary.org/obo/UBERON_0002435 striatum http://purl.obolibrary.org/obo/UBERON_0014701 extraembryonic vascular system http://purl.obolibrary.org/obo/UBERON_0007798 vascular system A vascular system that overlaps a umbilical cord and is part of a entire extraembryonic component. https://purl.brain-bican.org/ontology/dhbao/DHBA_10333 striatum https://purl.brain-bican.org/ontology/dhbao/DHBA_10157 gray matter of forebrain http://purl.obolibrary.org/obo/UBERON_0014702 frontonasal process epithelium http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue An epithelium that is part of a frontonasal prominence. https://purl.brain-bican.org/ontology/mbao/MBA_1022 Globus pallidus, external segment http://purl.obolibrary.org/obo/UBERON_0002476 lateral globus pallidus http://purl.obolibrary.org/obo/UBERON_0014703 anal membrane ectodermal component http://purl.obolibrary.org/obo/UBERON_0010371 ecto-epithelium A unilaminar epithelium that develops_from a ectoderm and is part of a anal region. https://purl.brain-bican.org/ontology/mbao/MBA_1031 Globus pallidus, internal segment http://purl.obolibrary.org/obo/UBERON_0002477 medial globus pallidus http://purl.obolibrary.org/obo/UBERON_0014704 pleuroperitoneal canal lumen http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space An anatomical space that is enclosed by a pleuroperitoneal canal. https://purl.brain-bican.org/ontology/dhbao/DHBA_10344 internal segment of globus pallidus https://purl.brain-bican.org/ontology/dhbao/DHBA_10157 gray matter of forebrain https://purl.brain-bican.org/ontology/mbao/MBA_170 Dorsal part of the lateral geniculate complex http://purl.obolibrary.org/obo/UBERON_0006331 brainstem nucleus http://purl.obolibrary.org/obo/UBERON_0014705 median lingual swelling epithelium http://purl.obolibrary.org/obo/UBERON_0005911 endo-epithelium An epithelium that is part of a median lingual swelling. https://purl.brain-bican.org/ontology/dhbao/DHBA_10430 dorsal lateral geniculate nucleus https://purl.brain-bican.org/ontology/dhbao/DHBA_10440 posterior nucleus of thalamus http://purl.obolibrary.org/obo/UBERON_0014716 interlobular duct http://purl.obolibrary.org/obo/UBERON_0035050 excretory duct A duct that is located between lobules, within the thin connective tissue septa that separate lobules. All interlobular ducts are excretory. https://purl.brain-bican.org/ontology/dhbao/DHBA_266441551 anterior hypothalamic area http://purl.obolibrary.org/obo/UBERON_0002550 anterior hypothalamic region http://purl.obolibrary.org/obo/UBERON_0014717 mucous acinus http://purl.obolibrary.org/obo/UBERON_0011858 acinus of exocrine gland The secretory unit of a mucous gland. The acinar portion is composed of mucous secreting cells. http://purl.obolibrary.org/obo/UBERON_0035763 cavity of cardiac chamber http://purl.obolibrary.org/obo/UBERON_0002553 anatomical cavity http://purl.obolibrary.org/obo/UBERON_0014719 intralobular duct http://purl.obolibrary.org/obo/UBERON_0000058 duct A duct that is located within a lobule, with no more connective tissue intervening between ducts and secretory units (i.e., acini or tubules) than between adjacent secretory units. Intercalated and striated ducts are intralobular. http://purl.obolibrary.org/obo/UBERON_0035809 serous cavity http://purl.obolibrary.org/obo/UBERON_0002553 anatomical cavity https://purl.brain-bican.org/ontology/dhbao/DHBA_12405 basilar part of pons http://purl.obolibrary.org/obo/UBERON_0002567 basal part of pons http://purl.obolibrary.org/obo/UBERON_0014720 interlobar duct http://purl.obolibrary.org/obo/UBERON_0035050 excretory duct A duct that is located between lobes, within conspicuous, thick connective tissue septa that separate lobes. All interlobar ducts are excretory. https://purl.brain-bican.org/ontology/mbao/MBA_709 Ventral posterior complex of the thalamus http://purl.obolibrary.org/obo/UBERON_0006331 brainstem nucleus http://purl.obolibrary.org/obo/UBERON_0014725 intercalated duct http://purl.obolibrary.org/obo/UBERON_0014719 intralobular duct A small duct which drains individual secretory units. These are usually inconspicuous, lined by a simple epithelium consisting of low cuboidal cells. https://purl.brain-bican.org/ontology/dhbao/DHBA_10423 ventral posterior nucleus of thalamus http://purl.obolibrary.org/obo/UBERON_0002596 ventral posterior nucleus of thalamus http://purl.obolibrary.org/obo/UBERON_0014726 intercalated duct of pancreas http://purl.obolibrary.org/obo/UBERON_0014725 intercalated duct An intercalated duct that is part of a pancreas. https://purl.brain-bican.org/ontology/dhbao/DHBA_12155 limbic lobe http://purl.obolibrary.org/obo/UBERON_0002600 limbic lobe http://purl.obolibrary.org/obo/UBERON_0014727 intercalated duct of salivary gland http://purl.obolibrary.org/obo/UBERON_0014725 intercalated duct The tiny tubules with a very thin epithelial layer in the salivary glands running from the salivary acini into the striated duct. https://purl.brain-bican.org/ontology/mbao/MBA_607 Cochlear nuclei http://purl.obolibrary.org/obo/UBERON_0002610 cochlear nuclear complex https://purl.brain-bican.org/ontology/dhbao/DHBA_12437 cochlear nuclei https://purl.brain-bican.org/ontology/dhbao/DHBA_10654 gray matter of the hindbrain http://purl.obolibrary.org/obo/UBERON_0014729 striated duct of salivary gland http://purl.obolibrary.org/obo/UBERON_0014719 intralobular duct Gland duct which connects an intercalated duct to an interlobular duct in a salivary gland. https://purl.brain-bican.org/ontology/mbao/MBA_397 ventral tegmental decussation https://purl.brain-bican.org/ontology/mbao/MBA_1009 fiber tracts http://purl.obolibrary.org/obo/UBERON_0014734 allocortex http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain One of two types of cerebral cortex defined on the basis of cytoarchitecture and fetal development. The other is neocortex. Allocortex does not pass through a prenatal phase of six-layered structure and has three or four layers in the mature brain ( Schiebler-1999 ). Allocortex has three subtypes: paleocortex, archicortex and periallocortex. This definition differs from that in some older sources, which excluded the olfactory bulb and the accessory olfactory bulb ( Carpenter-1983 ). https://purl.brain-bican.org/ontology/dhbao/DHBA_12366 ventral tegmental decussation http://purl.obolibrary.org/obo/UBERON_0002615 ventral tegmental decussation https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain http://purl.obolibrary.org/obo/UBERON_0014735 paleocortex http://purl.obolibrary.org/obo/UBERON_0014734 allocortex Part of the allocortex defined on the basis of cytoarchitecture. The other two are archicortex and periallocortex. It consists of very thin, primitive cortex with few clearly defined layers. It is distinguished ontogenetically by the fact that it does not develop through a cortical plate. It includes the olfactory bulb, accessory olfactory bulb, olfactory tubercle, septum, prepyriform area and periamygdalar area ( Stephan-1975 ). (adapted from Brain Info). https://purl.brain-bican.org/ontology/mbao/MBA_133 Periventricular hypothalamic nucleus, preoptic part http://purl.obolibrary.org/obo/UBERON_0006568 hypothalamic nucleus https://purl.brain-bican.org/ontology/mbao/MBA_452 Median preoptic nucleus http://purl.obolibrary.org/obo/UBERON_0006568 hypothalamic nucleus http://purl.obolibrary.org/obo/UBERON_0014769 palpebral vein http://purl.obolibrary.org/obo/UBERON_0009141 craniocervical region vein A blood vessel that drains from from an eyelid. https://purl.brain-bican.org/ontology/dhbao/DHBA_13063 median preoptic nucleus http://purl.obolibrary.org/obo/UBERON_0006568 hypothalamic nucleus https://purl.brain-bican.org/ontology/dhbao/DHBA_12239 midbrain reticular formation https://purl.brain-bican.org/ontology/dhbao/DHBA_10649 gray matter of midbrain http://purl.obolibrary.org/obo/UBERON_0014770 palpebral artery http://purl.obolibrary.org/obo/UBERON_0003496 head blood vessel An artery that supplies blood to an eyelid. https://purl.brain-bican.org/ontology/dhbao/DHBA_10350 septal nuclei https://purl.brain-bican.org/ontology/dhbao/DHBA_10157 gray matter of forebrain http://purl.obolibrary.org/obo/UBERON_0014775 prosomere http://purl.obolibrary.org/obo/UBERON_0004731 neuromere A neuromere that is part of the presumptive forebrain. https://purl.brain-bican.org/ontology/mbao/MBA_242 Lateral septal nucleus http://purl.obolibrary.org/obo/UBERON_0002667 lateral septal nucleus http://purl.obolibrary.org/obo/UBERON_0014776 midbrain neuromere http://purl.obolibrary.org/obo/UBERON_0004731 neuromere A neuromere that is part of the presumptive midbrain. https://purl.brain-bican.org/ontology/dhbao/DHBA_10352 lateral septal nucleus http://purl.obolibrary.org/obo/UBERON_0002667 lateral septal nucleus https://purl.brain-bican.org/ontology/mbao/MBA_832 oculomotor nerve https://purl.brain-bican.org/ontology/mbao/MBA_967 cranial nerves http://purl.obolibrary.org/obo/UBERON_0014777 spinal neuromere http://purl.obolibrary.org/obo/UBERON_0004731 neuromere A neuromere that is part of the presumptive spinal cord. https://purl.brain-bican.org/ontology/dhbao/DHBA_12376 root of oculomotor nerve http://purl.obolibrary.org/obo/UBERON_0002668 oculomotor nerve root http://purl.obolibrary.org/obo/UBERON_0014783 cloacal muscle http://purl.obolibrary.org/obo/UBERON_0013765 digestive system element Any muscle organ that is part of a cloaca. https://purl.brain-bican.org/ontology/mbao/MBA_763 Vascular organ of the lamina terminalis https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions http://purl.obolibrary.org/obo/UBERON_0014790 lingual septum http://purl.obolibrary.org/obo/UBERON_0003037 septum The lingual septum consists of a vertical layer of fibrous tissue, extending throughout the entire length of the median plane of the tongue, though not quite reaching the dorsum. It is thicker behind than in front, and occasionally contains a small fibrocartilage, about 6 mm. in length. It is well displayed by making a vertical section across the organ. https://purl.brain-bican.org/ontology/dhbao/DHBA_12106 organum vasculosum laminae terminalis http://purl.obolibrary.org/obo/UBERON_0002689 supraoptic crest https://purl.brain-bican.org/ontology/mbao/MBA_272 Anteroventral periventricular nucleus http://purl.obolibrary.org/obo/UBERON_0006331 brainstem nucleus http://purl.obolibrary.org/obo/UBERON_0014791 musculature of forelimb stylopod http://purl.obolibrary.org/obo/UBERON_0004474 musculature of arm Any collection of muscles that is part of the forelimb stylopod region [Automatically generated definition]. https://purl.brain-bican.org/ontology/dhbao/DHBA_13061 anteroventral periventricular nucleus http://purl.obolibrary.org/obo/UBERON_0002690 anteroventral periventricular nucleus http://purl.obolibrary.org/obo/UBERON_0014792 musculature of pelvic complex http://purl.obolibrary.org/obo/UBERON_0001015 musculature Any collection of muscles that is part of a pelvic complex. The pelvic complex comprises the pelvic girdle and the associated limb or fin. https://purl.brain-bican.org/ontology/mbao/MBA_749 Ventral tegmental area https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions http://purl.obolibrary.org/obo/UBERON_0014793 musculature of pectoral complex http://purl.obolibrary.org/obo/UBERON_0001015 musculature Any collection of muscles that is part of a pectoral complex. The pectoral complex comprises the pectoral girdle and the associated limb or fin. https://purl.brain-bican.org/ontology/dhbao/DHBA_12261 ventral tegmental area http://purl.obolibrary.org/obo/UBERON_0002691 ventral tegmental area https://purl.brain-bican.org/ontology/mbao/MBA_1008 Geniculate group, dorsal thalamus http://purl.obolibrary.org/obo/UBERON_0006331 brainstem nucleus http://purl.obolibrary.org/obo/UBERON_0014794 pectoral appendage muscle http://purl.obolibrary.org/obo/UBERON_0010891 pectoral complex muscle Any muscle organ that is part of a pectoral appendage (forelimb or pectoral fin). https://purl.brain-bican.org/ontology/dhbao/DHBA_12776 corticospinal tract http://purl.obolibrary.org/obo/UBERON_0007702 tract of brain http://purl.obolibrary.org/obo/UBERON_0014795 pelvic appendage muscle http://purl.obolibrary.org/obo/UBERON_0010890 pelvic complex muscle Any muscle organ that is part of a pelvic appendage (hindlimb or pelvic fin). https://purl.brain-bican.org/ontology/mbao/MBA_126 Periventricular hypothalamic nucleus, posterior part http://purl.obolibrary.org/obo/UBERON_0006331 brainstem nucleus https://purl.brain-bican.org/ontology/mbao/MBA_1020 Posterior complex of the thalamus http://purl.obolibrary.org/obo/UBERON_0002709 posterior nuclear complex of thalamus http://purl.obolibrary.org/obo/UBERON_0014889 left hemisphere of cerebellum http://purl.obolibrary.org/obo/UBERON_0002245 cerebellar hemisphere A cerebellar hemisphere that is in_the_left_side_of a cerebellum. https://purl.brain-bican.org/ontology/dhbao/DHBA_10428 posterior nuclear complex of thalamus https://purl.brain-bican.org/ontology/dhbao/DHBA_10157 gray matter of forebrain http://purl.obolibrary.org/obo/UBERON_0014890 right hemisphere of cerebellum http://purl.obolibrary.org/obo/UBERON_0002245 cerebellar hemisphere A cerebellar hemisphere that is in_the_right_side_of a cerebellum. https://purl.brain-bican.org/ontology/mbao/MBA_863 rubrospinal tract https://purl.brain-bican.org/ontology/mbao/MBA_1009 fiber tracts http://purl.obolibrary.org/obo/UBERON_0014891 brainstem white matter http://purl.obolibrary.org/obo/UBERON_0003544 brain white matter White matter that is part of a brainstem [Automatically generated definition]. https://purl.brain-bican.org/ontology/dhbao/DHBA_12782 rubrospinal tract http://purl.obolibrary.org/obo/UBERON_0002714 rubrospinal tract http://purl.obolibrary.org/obo/UBERON_0014892 skeletal muscle organ, vertebrate http://purl.obolibrary.org/obo/UBERON_0001630 muscle organ A muscle organ that consists of skeletal muscle tissue ensheathed in epimysium, that develops from myotome and that is innervated by some somatic motor neuron. Skeletal muscles are typically attached (via a tendon) to a bone but there are exceptions (e.g. intrinsic tongue muscles). https://purl.brain-bican.org/ontology/mbao/MBA_933 vestibulocochlear nerve https://purl.brain-bican.org/ontology/mbao/MBA_967 cranial nerves https://purl.brain-bican.org/ontology/dhbao/DHBA_12868 root of vestibulocochlear nerve http://purl.obolibrary.org/obo/UBERON_0002731 vestibulocochlear nerve root https://purl.brain-bican.org/ontology/mbao/MBA_138 Lateral group of the dorsal thalamus http://purl.obolibrary.org/obo/UBERON_0006331 brainstem nucleus http://purl.obolibrary.org/obo/UBERON_0014903 primordial vasculature http://purl.obolibrary.org/obo/UBERON_0001048 primordium A portion of tissue that will develop into vasculature. https://purl.brain-bican.org/ontology/dhbao/DHBA_10349 basal forebrain http://purl.obolibrary.org/obo/UBERON_0002743 basal forebrain https://purl.brain-bican.org/ontology/mbao/MBA_637 Ventral group of the dorsal thalamus http://purl.obolibrary.org/obo/UBERON_0006331 brainstem nucleus http://purl.obolibrary.org/obo/UBERON_0014907 intersomitic vessel http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure One of the primary blood vessel sprouts that originate from the dorsal aorta and posterior cardinal vein and align dorsoventrally at the myotomal boundaries between somites. https://purl.brain-bican.org/ontology/mbao/MBA_101 Ventral cochlear nucleus http://purl.obolibrary.org/obo/UBERON_0002828 ventral cochlear nucleus https://purl.brain-bican.org/ontology/dhbao/DHBA_12439 ventral cochlear nucleus http://purl.obolibrary.org/obo/UBERON_0002828 ventral cochlear nucleus http://purl.obolibrary.org/obo/UBERON_0014930 perivascular space http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space The space between a blood vessel and the pia mater. https://purl.brain-bican.org/ontology/mbao/MBA_96 Dorsal cochlear nucleus http://purl.obolibrary.org/obo/UBERON_0002829 dorsal cochlear nucleus http://purl.obolibrary.org/obo/UBERON_0014935 cerebral cortex marginal layer http://purl.obolibrary.org/obo/UBERON_0014950 layer of developing cerebral cortex Developing superficial cortical layer located just under the pia matter, develops from the marginal layer of the neural tube and becomes cortical layer I. https://purl.brain-bican.org/ontology/dhbao/DHBA_12438 dorsal cochlear nucleus http://purl.obolibrary.org/obo/UBERON_0002829 dorsal cochlear nucleus http://purl.obolibrary.org/obo/UBERON_0015004 tibia endochondral element http://purl.obolibrary.org/obo/UBERON_0015022 hindlimb endochondral element The major preaxial endochondral element in the posterior zeugopod[Phenoscape]. https://purl.brain-bican.org/ontology/dhbao/DHBA_12440 ventral cochlear nucleus, rostral part http://purl.obolibrary.org/obo/UBERON_0002830 anteroventral cochlear nucleus http://purl.obolibrary.org/obo/UBERON_0015007 cervical vertebra endochondral element http://purl.obolibrary.org/obo/UBERON_0010913 vertebral element A vertebral endochondral element in the cervical region of the vertebral column. https://purl.brain-bican.org/ontology/dhbao/DHBA_12441 ventral cochlear nucleus, caudal part http://purl.obolibrary.org/obo/UBERON_0002831 posteroventral cochlear nucleus https://purl.brain-bican.org/ontology/mbao/MBA_773 Hypoglossal nucleus http://purl.obolibrary.org/obo/UBERON_0002871 hypoglossal nucleus http://purl.obolibrary.org/obo/UBERON_0015008 thoracic vertebra endochondral element http://purl.obolibrary.org/obo/UBERON_0010913 vertebral element A vertebral endochondral element in the thoracic region of the vertebral column. https://purl.brain-bican.org/ontology/dhbao/DHBA_12545 hypoglossal nucleus http://purl.obolibrary.org/obo/UBERON_0002871 hypoglossal nucleus http://purl.obolibrary.org/obo/UBERON_0015009 lumbar vertebra endochondral element http://purl.obolibrary.org/obo/UBERON_0010913 vertebral element A lumbar vertebra bone or its cartilage or pre-cartilage precursor. https://purl.brain-bican.org/ontology/mbao/MBA_131 Lateral amygdalar nucleus http://purl.obolibrary.org/obo/UBERON_0002886 lateral amygdaloid nucleus http://purl.obolibrary.org/obo/UBERON_0015010 sacral vertebra endochondral element http://purl.obolibrary.org/obo/UBERON_0010913 vertebral element A vertebra endochondral element that is part of the sacral region of the vertebral column. https://purl.brain-bican.org/ontology/dhbao/DHBA_10367 lateral nucleus http://purl.obolibrary.org/obo/UBERON_0002886 lateral amygdaloid nucleus http://purl.obolibrary.org/obo/UBERON_0015013 fibula endochondral element http://purl.obolibrary.org/obo/UBERON_0015022 hindlimb endochondral element The major postaxial endochondral element in the posterior zeugopod[Phenoscape]. https://purl.brain-bican.org/ontology/mbao/MBA_403 Medial amygdalar nucleus http://purl.obolibrary.org/obo/UBERON_0002892 medial amygdaloid nucleus http://purl.obolibrary.org/obo/UBERON_0015019 rib endochondral element http://purl.obolibrary.org/obo/UBERON_0010363 endochondral element A rib bone or its cartilage or pre-cartilage precursor. https://purl.brain-bican.org/ontology/mbao/MBA_619 Nucleus of the lateral olfactory tract http://purl.obolibrary.org/obo/UBERON_0002893 nucleus of lateral olfactory tract https://purl.brain-bican.org/ontology/dhbao/DHBA_10309 nucleus of lateral olfactory tract http://purl.obolibrary.org/obo/UBERON_0002893 nucleus of lateral olfactory tract http://purl.obolibrary.org/obo/UBERON_0015021 forelimb endochondral element http://purl.obolibrary.org/obo/UBERON_0015061 limb endochondral element A forelimb bone or its cartilage or pre-cartilage precursor. https://purl.brain-bican.org/ontology/mbao/MBA_698 Olfactory areas https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions http://purl.obolibrary.org/obo/UBERON_0015022 hindlimb endochondral element http://purl.obolibrary.org/obo/UBERON_0015061 limb endochondral element A hindlimb bone or its cartilage or pre-cartilage precursor. https://purl.brain-bican.org/ontology/dhbao/DHBA_10614 central sulcus https://purl.brain-bican.org/ontology/dhbao/DHBA_10610 cerebral sulci http://purl.obolibrary.org/obo/UBERON_0015023 phalanx endochondral element http://purl.obolibrary.org/obo/UBERON_0015063 autopod endochondral element A phalanx bone or its cartilage or pre-cartilage precursor. https://purl.brain-bican.org/ontology/dhbao/DHBA_10622 longitudinal fissure http://purl.obolibrary.org/obo/UBERON_0002921 longitudinal fissure http://purl.obolibrary.org/obo/UBERON_0015024 manual digit phalanx endochondral element http://purl.obolibrary.org/obo/UBERON_0015023 phalanx endochondral element A manual digit phalanx bone or its cartilage or pre-cartilage precursor. https://purl.brain-bican.org/ontology/mbao/MBA_10704 Dentate gyrus, polymorph layer http://purl.obolibrary.org/obo/UBERON_0002928 dentate gyrus polymorphic layer http://purl.obolibrary.org/obo/UBERON_0015030 pedal digit phalanx endochondral element http://purl.obolibrary.org/obo/UBERON_0015023 phalanx endochondral element A pedal digit phalanx bone or its cartilage or pre-cartilage precursor. http://purl.obolibrary.org/obo/UBERON_0015036 pedal digit metatarsal endochondral element http://purl.obolibrary.org/obo/UBERON_0015063 autopod endochondral element A pedal digit metatarsal bone or its cartilage or pre-cartilage precursor. https://purl.brain-bican.org/ontology/mbao/MBA_733 Ventral posteromedial nucleus of the thalamus http://purl.obolibrary.org/obo/UBERON_0006331 brainstem nucleus https://purl.brain-bican.org/ontology/dhbao/DHBA_10425 ventral posterior medial nucleus http://purl.obolibrary.org/obo/UBERON_0002945 ventral posteromedial nucleus of thalamus http://purl.obolibrary.org/obo/UBERON_0015042 manual digit metacarpus endochondral element http://purl.obolibrary.org/obo/UBERON_0015063 autopod endochondral element A manual digit metacarpus bone or its cartilage or pre-cartilage precursor. http://purl.obolibrary.org/obo/UBERON_0015049 carpus endochondral element http://purl.obolibrary.org/obo/UBERON_0015063 autopod endochondral element A carpus bone or its cartilage or pre-cartilage precursor. https://purl.brain-bican.org/ontology/mbao/MBA_1143 Cerebellar cortex, granular layer http://purl.obolibrary.org/obo/UBERON_0002956 granular layer of cerebellar cortex http://purl.obolibrary.org/obo/UBERON_0015050 tarsus endochondral element http://purl.obolibrary.org/obo/UBERON_0015063 autopod endochondral element A tarsus bone or its cartilage or pre-cartilage precursor. https://purl.brain-bican.org/ontology/dhbao/DHBA_10293 archicortex https://purl.brain-bican.org/ontology/dhbao/DHBA_10292 allocortex http://purl.obolibrary.org/obo/UBERON_0015052 femur endochondral element http://purl.obolibrary.org/obo/UBERON_0015022 hindlimb endochondral element A femur bone or its cartilage or pre-cartilage precursor. https://purl.brain-bican.org/ontology/mbao/MBA_1144 Cerebellar cortex, molecular layer http://purl.obolibrary.org/obo/UBERON_0002974 molecular layer of cerebellar cortex https://purl.brain-bican.org/ontology/mbao/MBA_1145 Cerebellar cortex, Purkinje layer http://purl.obolibrary.org/obo/UBERON_0002979 Purkinje cell layer of cerebellar cortex http://purl.obolibrary.org/obo/UBERON_0015053 humerus endochondral element http://purl.obolibrary.org/obo/UBERON_0015021 forelimb endochondral element A humerus bone or its cartilage or pre-cartilage precursor. https://purl.brain-bican.org/ontology/dhbao/DHBA_12852 flocculonodular lobe http://purl.obolibrary.org/obo/UBERON_0003012 flocculonodular lobe http://purl.obolibrary.org/obo/UBERON_0015054 iliac endochondral element http://purl.obolibrary.org/obo/UBERON_0010363 endochondral element An iliac bone or its cartilage or pre-cartilage precursor. https://purl.brain-bican.org/ontology/dhbao/DHBA_12416 pontine tegmentum http://purl.obolibrary.org/obo/UBERON_0003023 pontine tegmentum http://purl.obolibrary.org/obo/UBERON_0015056 ischial endochondral element http://purl.obolibrary.org/obo/UBERON_0010363 endochondral element An ischial bone or its cartilage or pre-cartilage precursor. https://purl.brain-bican.org/ontology/dhbao/DHBA_10440 posterior nucleus of thalamus http://purl.obolibrary.org/obo/UBERON_0003030 posterior nucleus of thalamus http://purl.obolibrary.org/obo/UBERON_0015057 scapula endochondral element http://purl.obolibrary.org/obo/UBERON_0010363 endochondral element A scapula bone or its cartilage or pre-cartilage precursor. https://purl.brain-bican.org/ontology/dhbao/DHBA_10542 ventricular zone http://purl.obolibrary.org/obo/UBERON_0003053 ventricular zone http://purl.obolibrary.org/obo/UBERON_0015059 orbitosphenoid endochondral element http://purl.obolibrary.org/obo/UBERON_0010363 endochondral element An orbitosphenoid bone or its cartilage or pre-cartilage precursor. https://purl.brain-bican.org/ontology/dhbao/DHBA_10153 neural plate http://purl.obolibrary.org/obo/UBERON_0003075 neural plate http://purl.obolibrary.org/obo/UBERON_0015060 sphenoid endochondral element http://purl.obolibrary.org/obo/UBERON_0010363 endochondral element A sphenoid bone or its cartilage or pre-cartilage precursor. http://purl.obolibrary.org/obo/UBERON_0036073 respiratory primordium mesenchyme http://purl.obolibrary.org/obo/UBERON_0003104 mesenchyme http://purl.obolibrary.org/obo/UBERON_0015061 limb endochondral element http://purl.obolibrary.org/obo/UBERON_0010363 endochondral element A limb bone or its cartilage or pre-cartilage precursor. https://purl.brain-bican.org/ontology/dhbao/DHBA_12320 roof plate of midbrain http://purl.obolibrary.org/obo/UBERON_0003299 roof plate of midbrain https://purl.brain-bican.org/ontology/dhbao/DHBA_12325 floor plate of midbrain http://purl.obolibrary.org/obo/UBERON_0003307 floor plate of midbrain http://purl.obolibrary.org/obo/UBERON_0015063 autopod endochondral element http://purl.obolibrary.org/obo/UBERON_0015061 limb endochondral element An endochondral element that is part of a autopod region. http://purl.obolibrary.org/obo/UBERON_0036343 wall of gallbladder http://purl.obolibrary.org/obo/UBERON_0003697 abdominal wall http://purl.obolibrary.org/obo/UBERON_0015064 autopod cartilage http://purl.obolibrary.org/obo/UBERON_0015063 autopod endochondral element An autopod endochondral element that is composed primarily of cartilage tissue. https://purl.brain-bican.org/ontology/mbao/MBA_463 Field CA3 https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions http://purl.obolibrary.org/obo/UBERON_0015078 proximal carpal endochondral element http://purl.obolibrary.org/obo/UBERON_0017750 proximal mesopodial endochondral element A proximal mesopodial endochondral element that is part of a forelimb. https://purl.brain-bican.org/ontology/dhbao/DHBA_10299 CA3 region of Hipp http://purl.obolibrary.org/obo/UBERON_0003883 CA3 field of hippocampus http://purl.obolibrary.org/obo/UBERON_0015079 proximal carpal cartilage http://purl.obolibrary.org/obo/UBERON_0035128 manus cartilage element A proximal carpal endochondral element that is composed primarily of cartilage tissue. https://purl.brain-bican.org/ontology/dhbao/DHBA_10300 CA4 region of Hipp http://purl.obolibrary.org/obo/UBERON_0003884 CA4 field of hippocampus http://purl.obolibrary.org/obo/UBERON_0015080 proximal carpal bone pre-cartilage condensation http://purl.obolibrary.org/obo/UBERON_0015078 proximal carpal endochondral element A proximal carpal endochondral element that is composed primarily of a pre-cartilage condensation. http://purl.obolibrary.org/obo/UBERON_0034969 epithelial layer of duct http://purl.obolibrary.org/obo/UBERON_0003914 epithelial tube http://purl.obolibrary.org/obo/UBERON_0015081 proximal tarsal endochondral element http://purl.obolibrary.org/obo/UBERON_0017750 proximal mesopodial endochondral element A proximal mesopodial endochondral element that is part of a hindlimb. http://purl.obolibrary.org/obo/UBERON_0035037 jaw epithelium http://purl.obolibrary.org/obo/UBERON_0003929 digestive tract epithelium http://purl.obolibrary.org/obo/UBERON_0015082 proximal tarsal cartilage http://purl.obolibrary.org/obo/UBERON_0035129 pes cartilage element A proximal tarsal endochondral element that is composed primarily of cartilage tissue. https://purl.brain-bican.org/ontology/dhbao/DHBA_12828 cerebellar fissures http://purl.obolibrary.org/obo/UBERON_0003980 cerebellum fissure https://purl.brain-bican.org/ontology/dhbao/DHBA_12698 cerebellar plate http://purl.obolibrary.org/obo/UBERON_0004008 cerebellar plate http://purl.obolibrary.org/obo/UBERON_0015083 proximal tarsal bone pre-cartilage condensation http://purl.obolibrary.org/obo/UBERON_0015081 proximal tarsal endochondral element A proximal tarsal endochondral element that is composed primarily of a pre-cartilage condensation. https://purl.brain-bican.org/ontology/dhbao/DHBA_10549 Ganglionic eminence (VZ in basal nuclei) http://purl.obolibrary.org/obo/UBERON_0004023 ganglionic eminence http://purl.obolibrary.org/obo/UBERON_0015129 epicardial fat http://purl.obolibrary.org/obo/UBERON_0035814 pericardial fat Visceral intrapericardial fat contiguous with the myocardial surface. https://purl.brain-bican.org/ontology/dhbao/DHBA_10550 medial ganglionic eminence http://purl.obolibrary.org/obo/UBERON_0004024 medial ganglionic eminence http://purl.obolibrary.org/obo/UBERON_0015130 connective tissue of prostate gland http://purl.obolibrary.org/obo/UBERON_0011822 dense irregular connective tissue A portion of connective tissue that is part of a prostate gland. https://purl.brain-bican.org/ontology/dhbao/DHBA_10551 lateral ganglionic eminence http://purl.obolibrary.org/obo/UBERON_0004025 lateral ganglionic eminence http://purl.obolibrary.org/obo/UBERON_0015144 autopod hair http://purl.obolibrary.org/obo/UBERON_0037459 hair of limb A strand of hair that is part of a autopod region. https://purl.brain-bican.org/ontology/dhbao/DHBA_10552 caudal ganglionic eminence http://purl.obolibrary.org/obo/UBERON_0004026 caudal ganglionic eminence http://purl.obolibrary.org/obo/UBERON_0015145 pes hair http://purl.obolibrary.org/obo/UBERON_0015144 autopod hair A strand of hair that is part of a pes. https://purl.brain-bican.org/ontology/mbao/MBA_703 Cortical subplate http://purl.obolibrary.org/obo/UBERON_0004035 cortical subplate http://purl.obolibrary.org/obo/UBERON_0015146 manus hair http://purl.obolibrary.org/obo/UBERON_0015144 autopod hair A strand of hair that is part of a manus. https://purl.brain-bican.org/ontology/mbao/MBA_91 Interposed nucleus http://purl.obolibrary.org/obo/UBERON_0004073 cerebellum interpositus nucleus http://purl.obolibrary.org/obo/UBERON_0015147 pinna hair http://purl.obolibrary.org/obo/UBERON_0022279 strand of hair on external ear A strand of hair that is part of a pinna. https://purl.brain-bican.org/ontology/dhbao/DHBA_12613 interpositus nucleus http://purl.obolibrary.org/obo/UBERON_0004073 cerebellum interpositus nucleus http://purl.obolibrary.org/obo/UBERON_0015148 tail hair http://purl.obolibrary.org/obo/UBERON_0001037 strand of hair A strand of hair that is part of a tail. https://purl.brain-bican.org/ontology/mbao/MBA_968 Nodulus (X) https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions http://purl.obolibrary.org/obo/UBERON_0015149 ventral hair http://purl.obolibrary.org/obo/UBERON_0001037 strand of hair A strand of hair that is part of a ventrum. http://purl.obolibrary.org/obo/UBERON_0036072 respiratory primordium epithelium http://purl.obolibrary.org/obo/UBERON_0015833 foregut epithelium http://purl.obolibrary.org/obo/UBERON_0015150 dorsal hair http://purl.obolibrary.org/obo/UBERON_0001037 strand of hair A strand of hair that is part of a dorsum. https://purl.brain-bican.org/ontology/mbao/MBA_236 Main olfactory bulb, mitral layer http://purl.obolibrary.org/obo/UBERON_0004186 olfactory bulb mitral cell layer http://purl.obolibrary.org/obo/UBERON_0015152 gland of ocular region http://purl.obolibrary.org/obo/UBERON_0002530 gland A gland that is typically found in or near the orbital region, in or around either the medial or lateral canthi, and is typically associated with secretions onto the eyeball or associated ducts. Includes the Harderian, nictitans and lacrimal glands. https://purl.brain-bican.org/ontology/dhbao/DHBA_11329 mitral cell layer of olfactory bulb http://purl.obolibrary.org/obo/UBERON_0004186 olfactory bulb mitral cell layer https://purl.brain-bican.org/ontology/mbao/MBA_579 external capsule http://purl.obolibrary.org/obo/UBERON_0004545 external capsule of telencephalon http://purl.obolibrary.org/obo/UBERON_0015154 lateral gland of orbital region http://purl.obolibrary.org/obo/UBERON_0015152 gland of ocular region A gland that is located in or around the ocular region, nearer the outer canthi. https://purl.brain-bican.org/ontology/dhbao/DHBA_10573 external capsule https://purl.brain-bican.org/ontology/dhbao/DHBA_10557 white matter of forebrain http://purl.obolibrary.org/obo/UBERON_0015155 conjunctival space http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space An anatomical space that is enclosed by a conjunctiva. https://purl.brain-bican.org/ontology/mbao/MBA_901 trigeminal nerve https://purl.brain-bican.org/ontology/mbao/MBA_967 cranial nerves http://purl.obolibrary.org/obo/UBERON_0015165 multi-unit eye http://purl.obolibrary.org/obo/UBERON_0000970 eye An eye consisting of multiple light-sensing organs. https://purl.brain-bican.org/ontology/dhbao/DHBA_12865 root of trigeminal nerve http://purl.obolibrary.org/obo/UBERON_0004673 trigeminal nerve root http://purl.obolibrary.org/obo/UBERON_0015172 endometrial blood vessel http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure A blood vessel that is part of a endometrium. http://purl.obolibrary.org/obo/UBERON_0015178 somite border http://purl.obolibrary.org/obo/UBERON_0007651 anatomical junction A region of somite adjacent to presomitic mesoderm. https://purl.brain-bican.org/ontology/mbao/MBA_798 facial nerve https://purl.brain-bican.org/ontology/mbao/MBA_967 cranial nerves https://purl.brain-bican.org/ontology/dhbao/DHBA_12862 root of facial nerve http://purl.obolibrary.org/obo/UBERON_0004674 facial nerve root http://purl.obolibrary.org/obo/UBERON_0015179 somite boundary epithelium http://purl.obolibrary.org/obo/UBERON_0000483 epithelium Epithelium located in the intersomitic region. https://purl.brain-bican.org/ontology/mbao/MBA_813 hypoglossal nerve https://purl.brain-bican.org/ontology/mbao/MBA_967 cranial nerves http://purl.obolibrary.org/obo/UBERON_0015181 neck of tooth http://purl.obolibrary.org/obo/UBERON_0001560 neck of organ The slightly constricted part of a tooth, between the crown and the root. https://purl.brain-bican.org/ontology/dhbao/DHBA_12886 root of hypoglossal nerve http://purl.obolibrary.org/obo/UBERON_0004675 hypoglossal nerve root http://purl.obolibrary.org/obo/UBERON_0015203 non-connected functional system http://purl.obolibrary.org/obo/UBERON_0034923 disconnected anatomical group An anatomical group whose component structures share a common function. https://purl.brain-bican.org/ontology/mbao/MBA_10703 Dentate gyrus, molecular layer http://purl.obolibrary.org/obo/UBERON_0004679 dentate gyrus molecular layer http://purl.obolibrary.org/obo/UBERON_0015204 glandular system http://purl.obolibrary.org/obo/UBERON_0015203 non-connected functional system A non-connected functional system that is composed primarily of a gland. https://purl.brain-bican.org/ontology/dhbao/DHBA_10391 dorsal thalamus http://purl.obolibrary.org/obo/UBERON_0004703 dorsal thalamus http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure Any structure that is placed on one side of the left-right axis of a bilaterian. https://purl.brain-bican.org/ontology/dhbao/DHBA_10311 piriform cortex http://purl.obolibrary.org/obo/UBERON_0004725 piriform cortex https://purl.brain-bican.org/ontology/dhbao/DHBA_10662 myelencephalon (medulla oblongata) http://purl.obolibrary.org/obo/UBERON_0005290 myelencephalon http://purl.obolibrary.org/obo/UBERON_0015214 arcuate ligament http://purl.obolibrary.org/obo/UBERON_0005181 thoracic segment organ A ligament that is part of a diaphragm. https://purl.brain-bican.org/ontology/mbao/MBA_695 Cortical plate http://purl.obolibrary.org/obo/UBERON_0005343 cortical plate http://purl.obolibrary.org/obo/UBERON_0015228 circulatory organ http://purl.obolibrary.org/obo/UBERON_0003103 compound organ A hollow, muscular organ, which, by contracting rhythmically, contributes to the circulation of lymph, blood or analogs. Examples: a chambered vertebrate heart; the tubular peristaltic heart of ascidians; the dorsal vessel of an insect; the lymoh heart of a reptile. https://purl.brain-bican.org/ontology/dhbao/DHBA_10515 cortical plate http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure https://purl.brain-bican.org/ontology/mbao/MBA_1041 Paraflocculus https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions http://purl.obolibrary.org/obo/UBERON_0015233 nucleus of dorsal thalamus http://purl.obolibrary.org/obo/UBERON_0007692 nucleus of thalamus A nucleus of brain that is part of a dorsal thalamus. https://purl.brain-bican.org/ontology/dhbao/DHBA_11327 glomerular layer of olfactory bulb http://purl.obolibrary.org/obo/UBERON_0005377 olfactory bulb glomerular layer http://purl.obolibrary.org/obo/UBERON_0015234 nucleus of ventral thalamus http://purl.obolibrary.org/obo/UBERON_0007692 nucleus of thalamus A nucleus of brain that is part of a ventral thalamus. https://purl.brain-bican.org/ontology/mbao/MBA_220 Main olfactory bulb, granule layer http://purl.obolibrary.org/obo/UBERON_0005378 olfactory bulb granule cell layer http://purl.obolibrary.org/obo/UBERON_0015238 pineal complex http://purl.obolibrary.org/obo/UBERON_0000477 anatomical cluster A cluster in the epithalamus that consists of the pineal body and any associated structures, such as the parapineal gland or the parietal organ. The complex is poorly developed in mammals. https://purl.brain-bican.org/ontology/mbao/MBA_632 Dentate gyrus, granule cell layer http://purl.obolibrary.org/obo/UBERON_0005381 dentate gyrus granule cell layer http://purl.obolibrary.org/obo/UBERON_0015249 digit skin http://purl.obolibrary.org/obo/UBERON_0015790 autopod skin A zone of skin that is part of a digit [Automatically generated definition]. https://purl.brain-bican.org/ontology/mbao/MBA_485 Striatum dorsal region http://purl.obolibrary.org/obo/UBERON_0005382 dorsal striatum https://purl.brain-bican.org/ontology/mbao/MBA_672 Caudoputamen http://purl.obolibrary.org/obo/UBERON_0005383 caudate-putamen http://purl.obolibrary.org/obo/UBERON_0015280 pancreas left lobe http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure A pancreatic lobule that is in_the_left_side_of a exocrine pancreas. https://purl.brain-bican.org/ontology/mbao/MBA_107 Somatomotor areas, Layer 1 http://purl.obolibrary.org/obo/UBERON_0005390 cortical layer I http://purl.obolibrary.org/obo/UBERON_0015281 pancreas right lobe http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure A pancreatic lobule that is in_the_right_side_of a exocrine pancreas. https://purl.brain-bican.org/ontology/mbao/MBA_644 Somatomotor areas, Layer 6a http://purl.obolibrary.org/obo/UBERON_0005395 cortical layer VI http://purl.obolibrary.org/obo/UBERON_0015329 respiratory system basement membrane http://purl.obolibrary.org/obo/UBERON_0005769 basement membrane of epithelium A basement membrane of epithelium that is part of a respiratory system. https://purl.brain-bican.org/ontology/mbao/MBA_493 Striatum ventral region http://purl.obolibrary.org/obo/UBERON_0005403 ventral striatum https://purl.brain-bican.org/ontology/dhbao/DHBA_12667 rhombomere 1 https://purl.brain-bican.org/ontology/dhbao/DHBA_12664 hindbrain neuromeres http://purl.obolibrary.org/obo/UBERON_0015418 urethra mesenchymal layer http://purl.obolibrary.org/obo/UBERON_0003104 mesenchyme A mesenchyme that is part of a urethra. https://purl.brain-bican.org/ontology/mbao/MBA_744 cerebellar commissure https://purl.brain-bican.org/ontology/mbao/MBA_1009 fiber tracts https://purl.brain-bican.org/ontology/mbao/MBA_1016 olfactory nerve layer of main olfactory bulb http://purl.obolibrary.org/obo/UBERON_0005978 olfactory bulb outer nerve layer http://purl.obolibrary.org/obo/UBERON_0015420 ureteral valve http://purl.obolibrary.org/obo/UBERON_0003978 valve A valve that is part of a ureter. http://purl.obolibrary.org/obo/UBERON_0015453 subcutaneous lymph node http://purl.obolibrary.org/obo/UBERON_0000029 lymph node A lymph node that is part of a hypodermis. https://purl.brain-bican.org/ontology/dhbao/DHBA_11326 olfactory nerve layer of olfactory bulb http://purl.obolibrary.org/obo/UBERON_0005978 olfactory bulb outer nerve layer http://purl.obolibrary.org/obo/UBERON_0015474 axilla skin http://purl.obolibrary.org/obo/UBERON_8480025 skin of clavicle region A zone of skin that is part of a axilla. http://purl.obolibrary.org/obo/UBERON_0015476 nose skin http://purl.obolibrary.org/obo/UBERON_1000021 skin of face A zone of skin that is part of a external nose. https://purl.brain-bican.org/ontology/dhbao/DHBA_10366 basolateral nuclear group https://purl.brain-bican.org/ontology/dhbao/DHBA_10157 gray matter of forebrain http://purl.obolibrary.org/obo/UBERON_0015480 proper hepatic artery http://purl.obolibrary.org/obo/UBERON_0001193 hepatic artery The hepatic artery proper (also proper hepatic artery), arises from the common hepatic artery and runs alongside the portal vein and the common bile duct to form the portal triad. The hepatic artery proper gives off a small supraduodenal artery to the duodenal bulb. Then the right gastric artery comes off and runs to the left along the lesser curvature of the stomach to meet the left gastric artery, which is a branch of the celiac trunk. It subsequently gives off the cystic artery, which feeds the gallbladder, before bifurcating into the right and left hepatic arteries. Of note, the right and left hepatic arteries may demonstrate variant anatomy. A replaced right hepatic artery may arise from the superior mesenteric artery (SMA) and a replaced left hepatic artery may arise from the left gastric artery. https://purl.brain-bican.org/ontology/dhbao/DHBA_10372 corticomedial nuclear group https://purl.brain-bican.org/ontology/dhbao/DHBA_10157 gray matter of forebrain https://purl.brain-bican.org/ontology/dhbao/DHBA_10664 rhombic lip http://purl.obolibrary.org/obo/UBERON_0006215 rhombic lip http://purl.obolibrary.org/obo/UBERON_0015481 left hepatic artery http://purl.obolibrary.org/obo/UBERON_0015796 liver blood vessel A hepatic artery that is part of a left lobe of liver. https://purl.brain-bican.org/ontology/dhbao/DHBA_10595 ventricles of forebrain http://purl.obolibrary.org/obo/UBERON_0006284 early prosencephalic vesicle https://purl.brain-bican.org/ontology/mbao/MBA_118 Periventricular hypothalamic nucleus, intermediate part http://purl.obolibrary.org/obo/UBERON_8440008 periventricular hypothalamic nucleus, intermediate part http://purl.obolibrary.org/obo/UBERON_0015482 right hepatic artery http://purl.obolibrary.org/obo/UBERON_0015796 liver blood vessel A hepatic artery that is part of a right lobe of liver. https://purl.brain-bican.org/ontology/mbao/MBA_803 Pallidum http://purl.obolibrary.org/obo/UBERON_0011300 gray matter of telencephalon https://purl.brain-bican.org/ontology/mbao/MBA_818 Pallidum, dorsal region https://purl.brain-bican.org/ontology/mbao/MBA_803 Pallidum http://purl.obolibrary.org/obo/UBERON_0015485 choledocho-duodenal junction http://purl.obolibrary.org/obo/UBERON_1100000 digestive tract junction Hat part of the duodenal wall traversed by the ductus choledochus, ductus pancreaticus, and ampulla. https://purl.brain-bican.org/ontology/mbao/MBA_967 cranial nerves https://purl.brain-bican.org/ontology/mbao/MBA_1009 fiber tracts https://purl.brain-bican.org/ontology/dhbao/DHBA_12888 root of vagus nerve http://purl.obolibrary.org/obo/UBERON_0011213 root of vagus nerve http://purl.obolibrary.org/obo/UBERON_0015593 frontal gyrus http://purl.obolibrary.org/obo/UBERON_0000200 gyrus A gyrus that is part of a frontal cortex. https://purl.brain-bican.org/ontology/mbao/MBA_128 Midbrain reticular nucleus http://purl.obolibrary.org/obo/UBERON_0007415 nucleus of midbrain reticular formation https://purl.brain-bican.org/ontology/mbao/MBA_752 cerebellar peduncles http://purl.obolibrary.org/obo/UBERON_0007416 cerebellar peduncle http://purl.obolibrary.org/obo/UBERON_0015599 genu of corpus callosum http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain Part of corpus callosum comprising the 'kneelike' anterior bend (adapted from Nolte, The Human Brain, 6th ed., 2009 pg 664). https://purl.brain-bican.org/ontology/mbao/MBA_275 Lateral septal complex http://purl.obolibrary.org/obo/UBERON_0007628 lateral septal complex https://purl.brain-bican.org/ontology/mbao/MBA_466 alveus http://purl.obolibrary.org/obo/UBERON_0014532 white matter lamina of cerebral hemisphere http://purl.obolibrary.org/obo/UBERON_0015716 anal canal epithelium http://purl.obolibrary.org/obo/UBERON_0014703 anal membrane ectodermal component An epithelium that is part of a anal canal. https://purl.brain-bican.org/ontology/dhbao/DHBA_10570 alveus http://purl.obolibrary.org/obo/UBERON_0014532 white matter lamina of cerebral hemisphere http://purl.obolibrary.org/obo/UBERON_0015717 smooth muscle tissue layer of ejaculatory duct http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure A smooth muscle tissue that is part of a ejaculatory duct. https://purl.brain-bican.org/ontology/dhbao/DHBA_266441713 trigeminal nuclei https://purl.brain-bican.org/ontology/dhbao/DHBA_10654 gray matter of the hindbrain https://purl.brain-bican.org/ontology/mbao/MBA_997 brain http://purl.obolibrary.org/obo/UBERON_0008823 neural tube derived brain http://purl.obolibrary.org/obo/UBERON_0015766 epithelium of duct of salivary gland http://purl.obolibrary.org/obo/UBERON_0034969 epithelial layer of duct An epithelium that is part of a duct of salivary gland. http://purl.obolibrary.org/obo/UBERON_0015783 smooth muscle layer in fatty layer of subcutaneous tissue http://purl.obolibrary.org/obo/UBERON_0001135 smooth muscle tissue A smooth muscle tissue that is part of a hypodermis. https://purl.brain-bican.org/ontology/dhbao/DHBA_10155 brain http://purl.obolibrary.org/obo/UBERON_0008823 neural tube derived brain https://purl.brain-bican.org/ontology/dhbao/DHBA_146035120 roots of spinal nerves http://purl.obolibrary.org/obo/UBERON_0011215 central nervous system cell part cluster http://purl.obolibrary.org/obo/UBERON_0015786 respiratory segment of nasal mucosa http://purl.obolibrary.org/obo/UBERON_0001826 nasal cavity mucosa The portion of the nasal mucosa that is part of the respiratory system. https://purl.brain-bican.org/ontology/dhbao/DHBA_12182 pretectal nuclear complex http://purl.obolibrary.org/obo/UBERON_0014450 pretectal nucleus http://purl.obolibrary.org/obo/UBERON_0015787 upper respiratory conduit http://purl.obolibrary.org/obo/UBERON_0004111 anatomical conduit Any anatomical conduit which is part of the upper respiratory tract. https://purl.brain-bican.org/ontology/dhbao/DHBA_10665 upper (rostral) rhombic lip http://purl.obolibrary.org/obo/UBERON_0009841 upper rhombic lip http://purl.obolibrary.org/obo/UBERON_0015788 olfactory apparatus chamber http://purl.obolibrary.org/obo/UBERON_0015787 upper respiratory conduit An anatomical chamber that is part of the olfactory apparatus, consisting of cavity walls (nasal epithelium and mucosal layers) and the space bounded anteriorly by the nares and posteriorly by the choanae, when these structures are present. http://purl.obolibrary.org/obo/UBERON_0036375 wall of right ureter http://purl.obolibrary.org/obo/UBERON_0009916 wall of ureter http://purl.obolibrary.org/obo/UBERON_0036376 wall of left ureter http://purl.obolibrary.org/obo/UBERON_0009916 wall of ureter http://purl.obolibrary.org/obo/UBERON_0015790 autopod skin http://purl.obolibrary.org/obo/UBERON_0001419 skin of limb A zone of skin that is part of a autopod region. http://purl.obolibrary.org/obo/UBERON_0015791 digit connective tissue http://purl.obolibrary.org/obo/UBERON_0003587 limb connective tissue A portion of connective tissue that is part of a digit. https://purl.brain-bican.org/ontology/dhbao/DHBA_12531 retrotrapezoid nucleus http://purl.obolibrary.org/obo/UBERON_0009918 retrotrapezoid nucleus https://purl.brain-bican.org/ontology/mbao/MBA_507 Main olfactory bulb https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions http://purl.obolibrary.org/obo/UBERON_0015794 left lung lobar bronchus epithelium http://purl.obolibrary.org/obo/UBERON_0003365 epithelium of left lung An epithelium that is part of a lobar bronchus of left lung. https://purl.brain-bican.org/ontology/dhbao/DHBA_12322 basal plate of midbrain https://purl.brain-bican.org/ontology/dhbao/DHBA_10649 gray matter of midbrain http://purl.obolibrary.org/obo/UBERON_0015795 right lung lobar bronchus epitheium http://purl.obolibrary.org/obo/UBERON_0003364 epithelium of right lung An epithelium that is part of a lobar bronchus of right lung. http://purl.obolibrary.org/obo/UBERON_0035555 lateral line sense organ http://purl.obolibrary.org/obo/UBERON_0010521 electroreceptor organ http://purl.obolibrary.org/obo/UBERON_0015796 liver blood vessel http://purl.obolibrary.org/obo/UBERON_0003497 abdomen blood vessel A blood vessel that is part of a liver. http://purl.obolibrary.org/obo/UBERON_0035128 manus cartilage element http://purl.obolibrary.org/obo/UBERON_0015064 autopod cartilage http://purl.obolibrary.org/obo/UBERON_0015807 ear epithelium http://purl.obolibrary.org/obo/UBERON_0019304 sensory organ epithelium An epithelium that is part of a ear. http://purl.obolibrary.org/obo/UBERON_0035129 pes cartilage element http://purl.obolibrary.org/obo/UBERON_0015064 autopod cartilage http://purl.obolibrary.org/obo/UBERON_0015808 eye epithelium http://purl.obolibrary.org/obo/UBERON_0007625 pigment epithelium of eye An epithelium that is part of a camera-type eye. https://purl.brain-bican.org/ontology/mbao/MBA_246 Midbrain reticular nucleus, retrorubral area https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions http://purl.obolibrary.org/obo/UBERON_0015813 middle ear epithelium http://purl.obolibrary.org/obo/UBERON_0015807 ear epithelium An epithelium that is part of a middle ear. https://purl.brain-bican.org/ontology/dhbao/DHBA_12289 retrorubral field http://purl.obolibrary.org/obo/UBERON_0011172 retrorubral area of midbrain reticular nucleus http://purl.obolibrary.org/obo/UBERON_0015814 outer ear epithelium http://purl.obolibrary.org/obo/UBERON_0015807 ear epithelium An epithelium that is part of a external ear. https://purl.brain-bican.org/ontology/mbao/MBA_917 vagus nerve https://purl.brain-bican.org/ontology/mbao/MBA_967 cranial nerves http://purl.obolibrary.org/obo/UBERON_0015833 foregut epithelium http://purl.obolibrary.org/obo/UBERON_0003929 digestive tract epithelium An epithelium that is part of a foregut. https://purl.brain-bican.org/ontology/dhbao/DHBA_12883 root of accessory nerve http://purl.obolibrary.org/obo/UBERON_0014615 accessory nerve root http://purl.obolibrary.org/obo/UBERON_0015834 duodenum lamina propria http://purl.obolibrary.org/obo/UBERON_0001238 lamina propria of small intestine A lamina propria that is part of a duodenum. https://purl.brain-bican.org/ontology/dhbao/DHBA_10610 cerebral sulci http://purl.obolibrary.org/obo/UBERON_0013118 sulcus of brain http://purl.obolibrary.org/obo/UBERON_0015870 lymph node of head http://purl.obolibrary.org/obo/UBERON_0000029 lymph node A lymph node that is part of a head. https://purl.brain-bican.org/ontology/dhbao/DHBA_10431 magnocellular layer of DLG http://purl.obolibrary.org/obo/UBERON_0013606 magnocellular layer of dorsal nucleus of lateral geniculate body http://purl.obolibrary.org/obo/UBERON_0015871 facial lymph node http://purl.obolibrary.org/obo/UBERON_0015870 lymph node of head Any of the lymph nodes that are part of a face. https://purl.brain-bican.org/ontology/mbao/MBA_495 Field CA3, pyramidal layer http://purl.obolibrary.org/obo/UBERON_0014550 pyramidal layer of CA3 https://purl.brain-bican.org/ontology/mbao/MBA_486 Field CA3, stratum oriens http://purl.obolibrary.org/obo/UBERON_0014553 CA3 stratum oriens http://purl.obolibrary.org/obo/UBERON_0015917 superficial lymph node http://purl.obolibrary.org/obo/UBERON_0000029 lymph node A lymph node that is located close to the surface. http://purl.obolibrary.org/obo/UBERON_0015918 deep lymph node http://purl.obolibrary.org/obo/UBERON_0000029 lymph node A lymph node that is located deeper within the organism, further from the surface. https://purl.brain-bican.org/ontology/mbao/MBA_504 Field CA3, stratum radiatum http://purl.obolibrary.org/obo/UBERON_0014556 CA3 stratum radiatum https://purl.brain-bican.org/ontology/mbao/MBA_717 accessory spinal nerve https://purl.brain-bican.org/ontology/mbao/MBA_1009 fiber tracts http://purl.obolibrary.org/obo/UBERON_0016398 lymph node of lower limb http://purl.obolibrary.org/obo/UBERON_0000029 lymph node A lymph node that is part of a hindlimb. http://purl.obolibrary.org/obo/UBERON_0035053 interlobular duct of salivary gland http://purl.obolibrary.org/obo/UBERON_0035049 excretory duct of salivary gland http://purl.obolibrary.org/obo/UBERON_0016399 lymph node of upper limb http://purl.obolibrary.org/obo/UBERON_0000029 lymph node A lymph node that is part of a forelimb. https://purl.brain-bican.org/ontology/dhbao/DHBA_10292 allocortex http://purl.obolibrary.org/obo/UBERON_0014734 allocortex http://purl.obolibrary.org/obo/UBERON_0016405 pulmonary capillary http://purl.obolibrary.org/obo/UBERON_0003526 respiratory system capillary A capillary that is part of a lung. https://purl.brain-bican.org/ontology/dhbao/DHBA_10306 paleocortex (semicortex) https://purl.brain-bican.org/ontology/dhbao/DHBA_10292 allocortex http://purl.obolibrary.org/obo/UBERON_0016422 compact bone of long bone http://purl.obolibrary.org/obo/UBERON_0005808 bone tissue of long bone A compact bone tissue that is part of a bone tissue of long bone. https://purl.brain-bican.org/ontology/mbao/MBA_1108 genu of corpus callosum https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions http://purl.obolibrary.org/obo/UBERON_0016423 compact bone of diaphysis http://purl.obolibrary.org/obo/UBERON_0005808 bone tissue of long bone A compact bone tissue that is part of a diaphysis. https://purl.brain-bican.org/ontology/dhbao/DHBA_10563 genu of corpus callosum http://purl.obolibrary.org/obo/UBERON_0015599 genu of corpus callosum http://purl.obolibrary.org/obo/UBERON_0016446 hair of head http://purl.obolibrary.org/obo/UBERON_0001037 strand of hair A strand of hair that is part of a head. https://purl.brain-bican.org/ontology/dhbao/DHBA_10208 parietal neocortex https://purl.brain-bican.org/ontology/dhbao/DHBA_10157 gray matter of forebrain http://purl.obolibrary.org/obo/UBERON_0016447 hair of trunk http://purl.obolibrary.org/obo/UBERON_0001037 strand of hair A strand of hair that is part of a trunk. https://purl.brain-bican.org/ontology/dhbao/DHBA_10235 temporal neocortex https://purl.brain-bican.org/ontology/dhbao/DHBA_10157 gray matter of forebrain http://purl.obolibrary.org/obo/UBERON_0016458 esophageal hiatus http://purl.obolibrary.org/obo/UBERON_0000161 orifice A hole in the diaphragm through which the esophagus passes. https://purl.brain-bican.org/ontology/dhbao/DHBA_10650 white matter of midbrain http://purl.obolibrary.org/obo/UBERON_0016554 white matter of midbrain http://purl.obolibrary.org/obo/UBERON_0016478 liver stroma http://purl.obolibrary.org/obo/UBERON_0003891 stroma A stroma that is part of a liver. https://purl.brain-bican.org/ontology/mbao/MBA_993 Secondary motor area https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions http://purl.obolibrary.org/obo/UBERON_0016479 capsule of liver http://purl.obolibrary.org/obo/UBERON_0003893 capsule A collagenous capsule covering the external surface of the liver. https://purl.brain-bican.org/ontology/dhbao/DHBA_10168 premotor cortex (area 6) http://purl.obolibrary.org/obo/UBERON_0016634 premotor cortex http://purl.obolibrary.org/obo/UBERON_0016481 bronchial lymph node http://purl.obolibrary.org/obo/UBERON_0000029 lymph node A lymph node that is part of a bronchus. http://purl.obolibrary.org/obo/UBERON_0016491 vertebral centrum element http://purl.obolibrary.org/obo/UBERON_0004765 skeletal element Skeletal element that functionally replaces the notochord[VSAP,modified]. https://purl.brain-bican.org/ontology/dhbao/DHBA_10668 white matter of hindbrain http://purl.obolibrary.org/obo/UBERON_0019258 white matter of hindbrain https://purl.brain-bican.org/ontology/dhbao/DHBA_10557 white matter of forebrain http://purl.obolibrary.org/obo/UBERON_0019261 white matter of forebrain http://purl.obolibrary.org/obo/UBERON_0016500 muscularis mucosa of fundus of urinary bladder http://purl.obolibrary.org/obo/UBERON_0006912 urinary bladder muscularis mucosa A muscularis mucosa that is part of a fundus of urinary bladder. http://purl.obolibrary.org/obo/UBERON_0016501 muscularis mucosae of fundus of stomach http://purl.obolibrary.org/obo/UBERON_0001203 muscularis mucosae of stomach A muscularis mucosa that is part of a fundus of stomach. https://purl.brain-bican.org/ontology/dhbao/DHBA_10654 gray matter of the hindbrain http://purl.obolibrary.org/obo/UBERON_0019263 gray matter of hindbrain https://purl.brain-bican.org/ontology/dhbao/DHBA_10157 gray matter of forebrain http://purl.obolibrary.org/obo/UBERON_0019264 gray matter of forebrain http://purl.obolibrary.org/obo/UBERON_0016502 stomach fundus lumen http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space An anatomical space that is enclosed by a fundus of stomach. https://purl.brain-bican.org/ontology/dhbao/DHBA_10649 gray matter of midbrain http://purl.obolibrary.org/obo/UBERON_0019267 gray matter of midbrain https://purl.brain-bican.org/ontology/mbao/MBA_808 glossopharyngeal nerve https://purl.brain-bican.org/ontology/mbao/MBA_967 cranial nerves http://purl.obolibrary.org/obo/UBERON_0016509 cavity of right ventricle http://purl.obolibrary.org/obo/UBERON_0035763 cavity of cardiac chamber Luminal space of the right ventricle of the heart. https://purl.brain-bican.org/ontology/dhbao/DHBA_12887 root of glossopharyngeal nerve http://purl.obolibrary.org/obo/UBERON_0019310 glossopharyngeal nerve root http://purl.obolibrary.org/obo/UBERON_0016510 epithelium of male urethra http://purl.obolibrary.org/obo/UBERON_0002325 epithelium of urethra An epithelium that is part of a male urethra. https://purl.brain-bican.org/ontology/mbao/MBA_840 olfactory nerve https://purl.brain-bican.org/ontology/mbao/MBA_967 cranial nerves http://purl.obolibrary.org/obo/UBERON_0016512 lumen of duodenum http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space An anatomical space that is part of a duodenum. http://purl.obolibrary.org/obo/UBERON_0016513 cavity of left atrium http://purl.obolibrary.org/obo/UBERON_0035763 cavity of cardiac chamber Luminal space of the left atrium of the heart. http://purl.obolibrary.org/obo/UBERON_0016515 muscular layer of prostatic urethra http://purl.obolibrary.org/obo/UBERON_0006660 muscular coat A muscular coat that is part of a prostatic urethra. http://purl.obolibrary.org/obo/UBERON_0016516 lamina propria of prostatic urethra http://purl.obolibrary.org/obo/UBERON_0002326 lamina propria of urethra A lamina propria that is part of a prostatic urethra. http://purl.obolibrary.org/obo/UBERON_0016517 lumen of jejunum http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space An anatomical space that is part of a jejunum. http://purl.obolibrary.org/obo/UBERON_0016519 muscularis mucosae of jejunum http://purl.obolibrary.org/obo/UBERON_0001210 muscularis mucosae of small intestine A muscularis mucosa that is part of a jejunum. https://purl.brain-bican.org/ontology/mbao/MBA_822 Retrohippocampal region https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions https://purl.brain-bican.org/ontology/mbao/MBA_365 thalamic peduncles http://purl.obolibrary.org/obo/UBERON_0022236 peduncle of thalamus http://purl.obolibrary.org/obo/UBERON_0016520 epithelium of female urethra http://purl.obolibrary.org/obo/UBERON_0002325 epithelium of urethra An epithelium that is part of a female urethra. https://purl.brain-bican.org/ontology/dhbao/DHBA_10568 forebrain ipsilateral fiber tracts http://purl.obolibrary.org/obo/UBERON_0022247 forebrain ipsilateral fiber tracts https://purl.brain-bican.org/ontology/dhbao/DHBA_10593 thalamic fasciculus http://purl.obolibrary.org/obo/UBERON_0022254 ventral thalamic fasciculus http://purl.obolibrary.org/obo/UBERON_0016522 cavity of right atrium http://purl.obolibrary.org/obo/UBERON_0035763 cavity of cardiac chamber Luminal space of the right atrium of the heart. https://purl.brain-bican.org/ontology/mbao/MBA_212 Main olfactory bulb, glomerular layer http://purl.obolibrary.org/obo/UBERON_0023934 olfactory bulb main glomerular layer https://purl.brain-bican.org/ontology/dhbao/DHBA_12024 forceps minor (frontalis) https://purl.brain-bican.org/ontology/dhbao/DHBA_10557 white matter of forebrain http://purl.obolibrary.org/obo/UBERON_0016526 lobe of cerebral hemisphere http://purl.obolibrary.org/obo/UBERON_0000064 organ part Subdivision of telencephalon which is one of a number of subdivisions of each hemisphere separated by both real landmarks (sulci and fissures) and arbitrary boundaries[FMA,modified]. https://purl.brain-bican.org/ontology/dhbao/DHBA_12695 marginal zone of cerebellum https://purl.brain-bican.org/ontology/dhbao/DHBA_12694 marginal zone of hindbrain https://purl.brain-bican.org/ontology/dhbao/DHBA_12694 marginal zone of hindbrain http://purl.obolibrary.org/obo/UBERON_0034709 hindbrain marginal layer http://purl.obolibrary.org/obo/UBERON_0016528 white matter of frontal lobe http://purl.obolibrary.org/obo/UBERON_0016527 white matter of cerebral lobe A white matter of cerebral lobe that is part of a frontal lobe. http://purl.obolibrary.org/obo/CLM_5022162 Cdh1,Acvr1c,Adamts15,Pax2 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022203 Slc25a34,C4b (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0016529 cortex of cerebral lobe http://purl.obolibrary.org/obo/UBERON_0005401 cerebral hemisphere gray matter Grey matter neocortex region of a lobe of the cerebral hemisphere. http://purl.obolibrary.org/obo/CLM_5022214 Glp1r 9 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5007972 Gm45459, Afap1l2 (NSforest). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0016530 parietal cortex http://purl.obolibrary.org/obo/UBERON_0016529 cortex of cerebral lobe Gray matter of the parietal region of the neocortex, located in the parietal lobe of gyrencephalic animals. It is continuous anteriorly with the frontal cortex, posteriorly with the occipital cortex and medially with the insular cortex and with the temporal cortex on the posterior/inferior border. http://purl.obolibrary.org/obo/CLM_5007040 Apod,Aqp1,Cldn5 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5016800 Slco1c1,Gria2,Shisa9 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0016531 white matter of parietal lobe http://purl.obolibrary.org/obo/UBERON_0016527 white matter of cerebral lobe A white matter of cerebral lobe that is part of a parietal lobe. http://purl.obolibrary.org/obo/CLM_5007039 Cldn5,Adamts12 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5007994 Tmem119, Cx3cr1 (NSforest). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0016534 white matter of temporal lobe http://purl.obolibrary.org/obo/UBERON_0016527 white matter of cerebral lobe A white matter of cerebral lobe that is part of a temporal lobe. http://purl.obolibrary.org/obo/CLM_5000360 Gja1,Hs3st3a1 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0016536 white matter of limbic lobe http://purl.obolibrary.org/obo/UBERON_0016527 white matter of cerebral lobe A white matter of cerebral lobe that is part of a limbic lobe. http://purl.obolibrary.org/obo/CLM_5001606 Thbd,Ccn3 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0016538 temporal cortex http://purl.obolibrary.org/obo/UBERON_0016529 cortex of cerebral lobe Gray matter of the temporal region of the neocortex, located in the temporal lobe in gyrencephalic animals. http://purl.obolibrary.org/obo/CLM_5022185 Sez6l,Unc13c (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022261 A330076C08Rik (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0016545 pharyngeal ectoderm http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue The external part of the developing pharynx that is made of ectoderm. During vertebrate development, pockets form in pharyngeal ectoderm between the pharyngeal arches. http://purl.obolibrary.org/obo/CLM_5016835 Pf4 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0016548 central nervous system gray matter layer http://purl.obolibrary.org/obo/UBERON_0022303 nervous system cell part layer A layer of of the central nervous system that is part of gray matter. http://purl.obolibrary.org/obo/CLM_5001601 Gpr17,Bmp4 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0016549 central nervous system white matter layer http://purl.obolibrary.org/obo/UBERON_0022303 nervous system cell part layer A layer of of the central nervous system that is composed of white matter. http://purl.obolibrary.org/obo/CLM_5000358 Aqp4,Cd38,Agt,Itih3 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5007722 Adora2a, Ppp1r1b (NSforest). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0016552 phlegm http://purl.obolibrary.org/obo/UBERON_0000912 mucus Mucus produced in the respiratory tract. http://purl.obolibrary.org/obo/CLM_5016802 Zfp536,Hopx (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0016553 respiratory system mucus http://purl.obolibrary.org/obo/UBERON_0000912 mucus Any mucus produced by a mucosae of the respiratory system. This includes the mucus produced in the nasal cavity (nasal mucus) and mucus produced in the respiratory tract (phlegm). http://purl.obolibrary.org/obo/CLM_5006969 Gfap,Ddn,Myoc,Rasl10b (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0016554 white matter of midbrain http://purl.obolibrary.org/obo/UBERON_0003544 brain white matter A white matter that is part of the midbrain. http://purl.obolibrary.org/obo/CLM_5022265 Cubn 4 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022263 Pde11a 3 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0016565 cerebral blood vessel http://purl.obolibrary.org/obo/UBERON_0003499 brain blood vessel A blood vessel that is part of a cerebellum. http://purl.obolibrary.org/obo/CLM_5001602 9630013A20Rik,Ptprb (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0016566 pit http://purl.obolibrary.org/obo/UBERON_0036215 anatomical surface region An roughly circular indentation in a surface. http://purl.obolibrary.org/obo/CLM_1001239 NS forest marker set of diffuse bipolar 4a cell (Human retina). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0016611 auditory hillocks, pharyngeal arch 1 derived http://purl.obolibrary.org/obo/UBERON_0000477 anatomical cluster A collection of protruberances derived from pharyngeal arch 1 that develop into the tragus, crus of the helix, and helix. http://purl.obolibrary.org/obo/CLM_1001240 NS forest marker set of OFFx cell (Human retina). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0016612 auditory hillocks, pharyngeal arch 2 derived http://purl.obolibrary.org/obo/UBERON_0000477 anatomical cluster A collection of protruberances derived from pharyngeal arch 2 that develop into the concha, antihelix and antitragus. http://purl.obolibrary.org/obo/CLM_1001241 NS forest marker set of cone retinal bipolar cell (Human retina). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_1001242 NS forest marker set of diffuse bipolar 3b cell (Human retina). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0016634 premotor cortex http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain The premotor cortex is an area of motor cortex lying within the frontal lobe of the brain. It extends 3 mm anterior to the primary motor cortex, near the Sylvian fissure, before narrowing to approximately 1 mm near the medial longitudinal fissure, which serves as the posterior border for the prefrontal cortex. The premotor cortex is largely equivalent to Brodmann area 6. Activity within this region is critical to the sensory guidance of movement and control of proximal and trunk muscles of the body. http://purl.obolibrary.org/obo/CLM_1001243 NS forest marker set of diffuse bipolar 1 cell (Human retina). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_1001244 NS forest marker set of diffuse bipolar 6 cell (Human retina). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0016854 dorsal part of optic cup http://purl.obolibrary.org/obo/UBERON_0000481 multi-tissue structure The dorsal region of the optic cup that gives rise to the dorsal part of the retina. http://purl.obolibrary.org/obo/CLM_1001245 NS forest marker set of diffuse bipolar 2 cell (Human retina). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_1001246 NS forest marker set of diffuse bipolar 4a cell (Human retina). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0016855 ventral part of optic cup http://purl.obolibrary.org/obo/UBERON_0000481 multi-tissue structure The ventral region of the optic cup that gives rise to the ventral part of the retina. http://purl.obolibrary.org/obo/CLM_1001247 NS forest marker set of flat midget bipolar cell (Human retina). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0016879 future central nervous system http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure Primordium that develops into the central nervous system. http://purl.obolibrary.org/obo/CLM_1001248 NS forest marker set of giant bipolar cell (Human retina). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0016880 future nervous system http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure Primordium that develops into the nervous system. http://purl.obolibrary.org/obo/CLM_1001249 NS forest marker set of diffuse bipolar 3a cell (Human retina). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0016884 shoulder joint http://purl.obolibrary.org/obo/UBERON_0000982 skeletal joint The joint that is formed by the union of the humerus, the scapula (or shoulder blade), and the clavicle (or collarbone). Commonly thought of as a single joint, the shoulder is actually made up of two separate joints - the glenohumeral and acromioclavicular joints. http://purl.obolibrary.org/obo/CLM_1001250 NS forest marker set of ON-blue cone bipolar cell (Human retina). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_1001251 NS forest marker set of rod bipolar cell (Human retina). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0016885 epithelium of terminal part of digestive tract http://purl.obolibrary.org/obo/UBERON_0003929 digestive tract epithelium Epithelium lining the distalmost portion of the digestive tract. http://purl.obolibrary.org/obo/CLM_1001252 NS forest marker set of invaginating midget bipolar cell (Human retina). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0016886 muscle tissue of terminal part of digestive tract http://purl.obolibrary.org/obo/UBERON_0002385 muscle tissue Any muscle tissue of the distalmost portion of the digestive tract. http://purl.obolibrary.org/obo/CLM_1001253 NS forest marker set of diffuse bipolar 3b cell (Human retina). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0016887 entire extraembryonic component http://purl.obolibrary.org/obo/UBERON_0000481 multi-tissue structure The part of the conceptus that may be lost before birth or will be discarded at birth, or when the embryo becomes an independent organism. http://purl.obolibrary.org/obo/CLM_1001254 NS forest marker set of diffuse bipolar 1 cell (Human retina). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0016888 transitional anatomical structure http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure An embryonic anatomical entity that will turn into one or more other anatomical entities, perhaps with other anatomical entities, later in development. http://purl.obolibrary.org/obo/CLM_1001255 NS forest marker set of OFFx cell (Human retina). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0016896 periosteum of long bone http://purl.obolibrary.org/obo/UBERON_0002515 periosteum A periosteum that is part of a long bone. http://purl.obolibrary.org/obo/CLM_1001256 NS forest marker set of diffuse bipolar 4b cell (Human retina). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0016928 metaphysis of fibula http://purl.obolibrary.org/obo/UBERON_0001438 metaphysis A metaphysis that is part of a fibula. http://purl.obolibrary.org/obo/CLM_1001257 NS forest marker set of diffuse bipolar 6 cell (Human retina). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0017163 skin bony tubercle http://purl.obolibrary.org/obo/UBERON_0013703 integumentary projection A bony structure embedded in skin, roughly equivalent to osteoderms. http://purl.obolibrary.org/obo/CLM_1001258 NS forest marker set of diffuse bipolar 2 cell (Human retina). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0017261 intertarsal sesamoid http://purl.obolibrary.org/obo/UBERON_0013631 sesamoid element A sesamoid element that is part of a tarsal skeleton. http://purl.obolibrary.org/obo/CLM_1001259 NS forest marker set of ON-blue cone bipolar cell (Human retina). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0017615 vomerine dentition http://purl.obolibrary.org/obo/UBERON_0010314 structure with developmental contribution from neural crest A set of teeth in which each tooth that attaches to a vomer. http://purl.obolibrary.org/obo/CLM_1001260 NS forest marker set of diffuse bipolar 3a cell (Human retina). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_1001261 NS forest marker set of cone retinal bipolar cell (Human retina). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0017648 ventral body wall http://purl.obolibrary.org/obo/UBERON_0000309 body wall The ventral part of the body wall. http://purl.obolibrary.org/obo/UBERON_0017649 dorsal body wall http://purl.obolibrary.org/obo/UBERON_0000309 body wall The dorsal part of the body wall. http://purl.obolibrary.org/obo/CLM_1001262 NS forest marker set of flat midget bipolar cell (Human retina). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_1001263 NS forest marker set of diffuse bipolar 4a cell (Human retina). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0017650 developing mesenchymal structure http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure A mesenchyme-derived anatomical entity undergoing a transtion to become another structure. http://purl.obolibrary.org/obo/CLM_1001264 NS forest marker set of invaginating midget bipolar cell (Human retina). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0017651 salivary gland primordium http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure A primordium that has the potential to develop into a saliva-secreting gland. http://purl.obolibrary.org/obo/CLM_1001265 NS forest marker set of giant bipolar cell (Human retina). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0017654 buccal gland http://purl.obolibrary.org/obo/UBERON_0000414 mucous gland Any of the small racemose mucous glands in the mucous membrane lining the cheeks. http://purl.obolibrary.org/obo/CLM_1001266 NS forest marker set of rod bipolar cell (Human retina). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0017672 abdominal viscera http://purl.obolibrary.org/obo/UBERON_0005172 abdomen element A viscus that is part of a abdomen. http://purl.obolibrary.org/obo/CLM_5006993 Cnmd,Sfta3-ps (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0017750 proximal mesopodial endochondral element http://purl.obolibrary.org/obo/UBERON_0015063 autopod endochondral element A mesopodial endochondral element that is in the most proximal part of the mesopodial skeleton, connected to the zeugopodial skeleton. http://purl.obolibrary.org/obo/CLM_5007036 Apod,Klk6,Dlc1 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5006356 Cngb3,Ush2a (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0017751 proximal mesopodial cartilage element http://purl.obolibrary.org/obo/UBERON_0017750 proximal mesopodial endochondral element A proximal mesopodial endochondral element that is composed primarily of cartilage tissue. http://purl.obolibrary.org/obo/CLM_5016792 Plcxd2,Fgf10 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0018111 muscle layer of rectum http://purl.obolibrary.org/obo/UBERON_0011198 muscle layer of large intestine A muscle layer that is part of the rectum. http://purl.obolibrary.org/obo/CLM_5016799 C4b,Prelp (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0018112 rectum smooth muscle tissue http://purl.obolibrary.org/obo/UBERON_0016886 muscle tissue of terminal part of digestive tract Any portion of smooth muscle tissue that is part of the rectum. http://purl.obolibrary.org/obo/CLM_5022237 Neil3,Irx2 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0018113 left kidney interstitium http://purl.obolibrary.org/obo/UBERON_0005215 kidney interstitium A kidney interstitium that is part of a left kidney. http://purl.obolibrary.org/obo/CLM_5016785 P3h2,Lrrc38 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0018114 right kidney interstitium http://purl.obolibrary.org/obo/UBERON_0005215 kidney interstitium A kidney interstitium that is part of a right kidney. http://purl.obolibrary.org/obo/CLM_5007020 Pdgfra,Olig1,Rmi2,Col27a1 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5006978 S1pr1,Thbs4,Gm29683,Slc39a12 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0018115 left renal pelvis http://purl.obolibrary.org/obo/UBERON_0001224 renal pelvis A renal pelvis that is part of a left ureter. http://purl.obolibrary.org/obo/CLM_5022178 Galnt15 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0018116 right renal pelvis http://purl.obolibrary.org/obo/UBERON_0001224 renal pelvis A renal pelvis that is part of a right ureter. http://purl.obolibrary.org/obo/CLM_5007029 9630013A20Rik,Dbx2,Rassf10 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0018117 left renal cortex interstitium http://purl.obolibrary.org/obo/UBERON_0018113 left kidney interstitium A renal cortex interstitium that is part of a left kidney. http://purl.obolibrary.org/obo/CLM_5022257 Il33,Gm5087 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0018118 right renal cortex interstitium http://purl.obolibrary.org/obo/UBERON_0018114 right kidney interstitium A renal cortex interstitium that is part of a right kidney. http://purl.obolibrary.org/obo/CLM_5000101 Prkch,Slc32a1,Drd1 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0018119 left renal medulla interstitium http://purl.obolibrary.org/obo/UBERON_0018113 left kidney interstitium A renal medulla interstitium that is part of a left kidney. http://purl.obolibrary.org/obo/CLM_5000348 Tmem204,Slc6a5 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5000351 Homer3,Tfap2b,Sorcs3,Cacna1e (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0018120 right renal medulla interstitium http://purl.obolibrary.org/obo/UBERON_0018114 right kidney interstitium A renal medulla interstitium that is part of a right kidney. http://purl.obolibrary.org/obo/CLM_5000353 Pcp2 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0018142 caudal vertebra endochondral element http://purl.obolibrary.org/obo/UBERON_0010913 vertebral element Any vertebra endochondral element that is part of the caudal region of the vertebral column (tail or coccyx). http://purl.obolibrary.org/obo/CLM_5000366 Pdgfra (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0018144 cervical rib http://purl.obolibrary.org/obo/UBERON_0003458 neck bone A rib that is attached to a cervical vertebra. http://purl.obolibrary.org/obo/CLM_5001564 Hmga2,Afap1l2 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0018145 lumbar rib http://purl.obolibrary.org/obo/UBERON_0002228 rib A rib that is attached to a lumbar vertebra. http://purl.obolibrary.org/obo/UBERON_0018146 transverse process of lumbar vertebra http://purl.obolibrary.org/obo/UBERON_0001077 transverse process of vertebra A transverse process that is part of a lumbar vertebra. http://purl.obolibrary.org/obo/CLM_5001565 Pthlh,Tfap2b,Rspo2 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5001566 Pax2,C1ql3,Tfap2b,Gabrb1 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0018150 skin of lower lip http://purl.obolibrary.org/obo/UBERON_0001458 skin of lip A zone of skin that is part of a lower lip. http://purl.obolibrary.org/obo/CLM_5001569 Dnah11,Sla,Gldc,Sdk2 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0018151 skin of upper lip http://purl.obolibrary.org/obo/UBERON_0001458 skin of lip A zone of skin that is part of a upper lip. http://purl.obolibrary.org/obo/CLM_5001574 Gabra6,Lmx1a (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0018154 ligament of middle ear http://purl.obolibrary.org/obo/UBERON_0000211 ligament A ligament that is part of a middle ear. http://purl.obolibrary.org/obo/CLM_5001579 Gfap,Lhfpl3,Gria1,Hopx (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0018226 pulmonary part of lymphatic system http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision An organ system subdivision that is the part of the lymphoid system that includes the pulmonary lymphatic vessels. http://purl.obolibrary.org/obo/CLM_5001580 Gja1,A330076C08Rik,Itih3,Gria2 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5001581 Myoc,Camk2a (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0018227 pulmonary lymphatic vessel http://purl.obolibrary.org/obo/UBERON_0003456 respiratory system lymphatic vessel A lymphatic vessel that is part of a lung. http://purl.obolibrary.org/obo/CLM_5001582 Hepacam,E330013P04Rik (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0018232 axillary sweat gland http://purl.obolibrary.org/obo/UBERON_0000382 apocrine sweat gland A sweat gland that is part of a axilla. http://purl.obolibrary.org/obo/CLM_5001583 Gja1,Grin2c,Dcc,Slc7a10 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0018234 stroma of pancreas http://purl.obolibrary.org/obo/UBERON_0003891 stroma A stroma that is part of a pancreas. http://purl.obolibrary.org/obo/CLM_5001588 Ednrb,Hs3st3a1,C230072F16Rik,Gria2 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0018235 capsule of pancreas http://purl.obolibrary.org/obo/UBERON_0003893 capsule A capsule that divides the parenchyma of the pancreas into lobes and lobules. http://purl.obolibrary.org/obo/CLM_5001593 Gpr50,Ccdc170,Nkx2-4 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0018239 rhombomere boundary http://purl.obolibrary.org/obo/UBERON_0007651 anatomical junction A boundary delimiting a rhombomere. http://purl.obolibrary.org/obo/CLM_5001615 Mrc1,Maf (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0018243 thymic artery http://purl.obolibrary.org/obo/UBERON_0001637 artery A vein that supplies blood to the thymus. http://purl.obolibrary.org/obo/CLM_5004314 Gnrh1 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0018246 thyroid vein http://purl.obolibrary.org/obo/UBERON_0001638 vein A vein that drains a thyroid gland. http://purl.obolibrary.org/obo/CLM_5006922 Il22,Edaradd (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0018247 cervical thymic artery http://purl.obolibrary.org/obo/UBERON_0018243 thymic artery An artery that supplies a cervical thymus. http://purl.obolibrary.org/obo/CLM_5006956 Gpr37l1,Ctxn3 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0018251 meningeal vein http://purl.obolibrary.org/obo/UBERON_0001638 vein One of the veins draining a meninix. http://purl.obolibrary.org/obo/CLM_5006957 Dao,Efemp1 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0018252 internal pudendal vein http://purl.obolibrary.org/obo/UBERON_0009029 pudendal vein Accompanying vein of internal pudendal artery. http://purl.obolibrary.org/obo/CLM_5006959 Gfap,Slc36a2,Sfrp5 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0018255 jejunal artery http://purl.obolibrary.org/obo/UBERON_0001637 artery A branch of the superior mesenteric artery that supplies the jejunum. http://purl.obolibrary.org/obo/CLM_5006960 Gfap,Sfrp5,Cldn10,Riiad1 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0018256 lacrimal vein http://purl.obolibrary.org/obo/UBERON_0001638 vein A vein that drains a lacrimal gland. http://purl.obolibrary.org/obo/CLM_5006961 Myoc,Six3os1,Slc36a2 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0018257 submucosa of digestive tract http://purl.obolibrary.org/obo/UBERON_0000009 submucosa Any portion of submucosa that lines the digestive tract. http://purl.obolibrary.org/obo/CLM_5006964 Gja1,A330076C08Rik,Sfrp5,Gria2 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0018260 layer of muscle tissue http://purl.obolibrary.org/obo/UBERON_0004923 organ component layer Any organ component layer that consists of muscle tissue. http://purl.obolibrary.org/obo/CLM_5006970 Myoc,Dio2,Lncpint (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0018261 muscular coat of digestive tract http://purl.obolibrary.org/obo/UBERON_0006660 muscular coat A muscular coat that is part of a digestive tract. http://purl.obolibrary.org/obo/CLM_5006971 Myoc,Sptbn2,Alpk1 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0018303 adrenal tissue http://purl.obolibrary.org/obo/UBERON_0000479 tissue Tissue that is part of some adrenal gland. http://purl.obolibrary.org/obo/CLM_5006972 Gm6145,E330013P04Rik,Slc39a12 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0018321 foramen for glossopharyngeal nerve http://purl.obolibrary.org/obo/UBERON_0013685 foramen of skull Foramen that allows the passge of the glossopharyngeal nerve (cranial nerve IX). http://purl.obolibrary.org/obo/CLM_5006973 Mcm6,Egfr,Pcsk6 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0018326 ilioischiadic foramen http://purl.obolibrary.org/obo/UBERON_0005744 bone foramen Situated just caudal to the acetabulum, the foramen is bound dorsally by the illium and ventrally by the ischium. The foramen transmitts the ischiadic nerves and vessels (Baumel et al. 1993). http://purl.obolibrary.org/obo/CLM_5006974 Gja1,Cxcl5,Ddn (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0018413 facial nerve canal http://purl.obolibrary.org/obo/UBERON_0013685 foramen of skull A Z-shaped canal running through the temporal bone from the internal acoustic meatus to the stylomastoid foramen. It is located within the middle ear region, according to its shape it is divided into three main segments: the labyrinthine, the tympanic, and the mastoidal segment . http://purl.obolibrary.org/obo/CLM_5006985 C230072F16Rik,Dipk1c,Ecrg4 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5006994 C230072F16Rik,Glp1r (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0018415 ethmoid foramen http://purl.obolibrary.org/obo/UBERON_0013685 foramen of skull An bone foramen in the ethmoid bone. http://purl.obolibrary.org/obo/CLM_5006995 Dynlrb2,Mylk3,Sfta3-ps (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0018543 lumen of intestine http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space The anatomical space within the intestine. http://purl.obolibrary.org/obo/CLM_5006996 Ccdc170,Nkx2-4,Dock8 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0018544 trigeminal nerve muscle http://purl.obolibrary.org/obo/UBERON_0001630 muscle organ Muscle innervated by the trigeminal nerve (Cranial Nerve V). http://purl.obolibrary.org/obo/CLM_5006997 Pdzph1,Wdr63,Dscaml1,P3h2 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0018664 neck of bone element http://purl.obolibrary.org/obo/UBERON_0005913 zone of bone organ The neck region of a bone organ. http://purl.obolibrary.org/obo/CLM_5006998 Ccdc146,Tbx3,Otx2 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0018674 heart vasculature http://purl.obolibrary.org/obo/UBERON_0006876 vasculature of organ An interconnected tubular multi-tissue structure that contains fluid that is actively transported around the heart. http://purl.obolibrary.org/obo/CLM_5006999 Gpr50,Frzb,Foxd2os (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5007013 Sspo,Wfdc2 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0018679 thoracic splanchnic nerve http://purl.obolibrary.org/obo/UBERON_0003824 nerve of thoracic segment Thoracic splanchnic nerves are splanchnic nerves that arise from the sympathetic trunk in the thorax and travel inferiorly to provide sympathetic innervation to the abdomen. The nerves contain preganglionic sympathetic and general visceral afferent fibers. http://purl.obolibrary.org/obo/CLM_5007014 2900040C04Rik,Tbc1d1 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0018685 nursing stage http://purl.obolibrary.org/obo/UBERON_0000105 life cycle stage A mammalian developmental stage that covers the period from birth until weaning. http://purl.obolibrary.org/obo/CLM_5007015 2900040C04Rik,Slc17a8 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5007016 Pdgfra,Pclaf,Mki67,Foxg1 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0019143 intramuscular adipose tissue http://purl.obolibrary.org/obo/UBERON_0001013 adipose tissue Adipose tissue which is located throughout skeletal muscle and is responsible for the marbling seen in certain cuts of beef. In humans, excess accumulation of intramuscular fat is associated with insulin resistance and type 2 diabetes. http://purl.obolibrary.org/obo/CLM_5007017 Pdgfra,Pclaf,Irx2 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0019204 skin epithelium http://purl.obolibrary.org/obo/UBERON_0000483 epithelium Any region of epithelium that is part of a skin region. http://purl.obolibrary.org/obo/CLM_5007018 Pdgfra,Olig1,Mms22l,Top2a (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0019207 chorioretinal region http://purl.obolibrary.org/obo/UBERON_0000481 multi-tissue structure The part of the eye that consists of both the retina and the optic choroid. http://purl.obolibrary.org/obo/CLM_5007019 Pdgfra,Olig1,Col27a1 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5007022 Gpr17,Bmp4,Zfp36l1 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0019258 white matter of hindbrain http://purl.obolibrary.org/obo/UBERON_0003544 brain white matter A white matter that is part of the hindbrain. http://purl.obolibrary.org/obo/CLM_5007023 Gpr17,Gp1bb,Pdzd2,Plekhg1 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0019261 white matter of forebrain http://purl.obolibrary.org/obo/UBERON_0003544 brain white matter A white matter that is part of the forebrain. http://purl.obolibrary.org/obo/CLM_5007025 9630013A20Rik,Bmp4,Mob3b (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0019262 white matter of myelencephalon http://purl.obolibrary.org/obo/UBERON_0019258 white matter of hindbrain A white matter that is part of the myelencephalon. http://purl.obolibrary.org/obo/CLM_5007026 9630013A20Rik,Rab32,Opalin (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0019307 epithelium of external nose http://purl.obolibrary.org/obo/UBERON_0019306 nose epithelium Epithelial layer that is part of the external part of the nose. http://purl.obolibrary.org/obo/CLM_5007028 9630013A20Rik,Grin2b (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0019311 root of olfactory nerve http://purl.obolibrary.org/obo/UBERON_0002211 nerve root The initial segment of an olfactory nerve, leaving the central nervous system. http://purl.obolibrary.org/obo/CLM_5007030 9630013A20Rik,Rgs16,Rhbdl2 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0019319 exocrine gland of integumental system http://purl.obolibrary.org/obo/UBERON_0003297 gland of integumental system An exocrine gland that is part of a integumental system. http://purl.obolibrary.org/obo/CLM_5007032 Opalin,Cxcl12,Efhd1 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0020358 accessory XI nerve nucleus http://purl.obolibrary.org/obo/UBERON_0007635 nucleus of medulla oblongata The spinal accessory nucleus lies within the cervical spinal cord (C1-C5) in the ventral horn. The nucleus ambiguus is classically said to provide the 'cranial component' of the accessory nerve. However, the very existence of this cranial component has been recently questioned and seen as contributing exclusively to the vagus nerve. The terminology continues to be used in describing both human anatomy, and that of other animals. http://purl.obolibrary.org/obo/CLM_5007033 9630013A20Rik,Ppp1r14a,Mroh3 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5007034 Prr5l,Hapln2,Enpp6,Grm7 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0020550 auricular blood vessel http://purl.obolibrary.org/obo/UBERON_0001981 blood vessel A blood vessel that supplies or drains an ear. http://purl.obolibrary.org/obo/CLM_5007037 Opalin,Grm3,Gm5087 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5007038 Mog,Anln,Gm32633 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0022254 ventral thalamic fasciculus http://purl.obolibrary.org/obo/UBERON_0005838 fasciculus of brain The thalamic fasciculus is a component of the subthalamus. It is sometimes considered synonymous with 'field H1 of Forel'. Nerve fibres forming a composite bundle containing cerebellothalamic (crossed) and pallidothalamic (uncrossed) fibres that is insinuated between the thalamus and zona incerta. The thalamic fasciculus consists of the joint fibers of the ansa lenticularis and the lenticular fasciculus, coming from different portions of the medial globus pallidus, before they jointly enter the ventral lateral nucleus of the thalamus. http://purl.obolibrary.org/obo/CLM_5007045 Prg4,Cubn (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5007062 C1qa,Tmem119 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0022284 lacrimal gland bud http://purl.obolibrary.org/obo/UBERON_0015808 eye epithelium The single bud-like invagination of the conjunctival fornix epithelium at the temporal aspect of the eye that signals lacrimal gland formation (Int Rev Cytol. 1996;168:1-80. Cell biology of the harderian gland). http://purl.obolibrary.org/obo/CLM_5007063 Mrc1,Pf4 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5007064 Mrc1,Pf4,Fos (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0022293 reproductive gland secretion http://purl.obolibrary.org/obo/UBERON_0000463 organism substance A portion of organism substance that is secreted by a reproductive gland. http://purl.obolibrary.org/obo/CLM_5007635 Gnrh1 (NSforest). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5007645 Gnb3, Pde6g, Gm44196 (NSforest). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0022302 short ciliary nerve http://purl.obolibrary.org/obo/UBERON_0011779 nerve of head region A branch of the ciliary ganglion that innervates the ciliary muscles, the iris, and the tunics of the eyeball. http://purl.obolibrary.org/obo/CLM_5007648 Tfap2a, Pvalb (NSforest). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5007649 Gabra6 (NSforest). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0022303 nervous system cell part layer http://purl.obolibrary.org/obo/UBERON_0005162 multi cell part structure Single layer of a laminar structure, identified by different density, arrangement or size of cells and processes arranged in flattened layers or lamina[CUMBO]. http://purl.obolibrary.org/obo/CLM_5007651 Olig1, Pllp (NSforest). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5007721 Pdyn, Rarb (NSforest). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0022317 olfactory cortex layer 1 http://purl.obolibrary.org/obo/UBERON_0022303 nervous system cell part layer Surface layer of the olfactory cortex that contains dendrites, fiber systems and a small number of neurons. It has been divided into a superficial part and a deep part. http://purl.obolibrary.org/obo/CLM_5007802 Gnrh1 2 (NSforest). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0022318 olfactory cortex layer 2 http://purl.obolibrary.org/obo/UBERON_0022303 nervous system cell part layer Middle layer of olfactory cortex lying deep to layer 1 and superficial to layer 3, characterized by a compact layer of cell bodies. It can be divided into a superficial part and a deep part. http://purl.obolibrary.org/obo/CLM_5007922 Pde6g, Gnb3, Gm44196 (NSforest). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0022350 visceral serous membrane http://purl.obolibrary.org/obo/UBERON_0004923 organ component layer Serous membrane layer that is adjacent to and lines an organ. http://purl.obolibrary.org/obo/CLM_5007968 Fam107b, Pvalb, Bhlhe22 (NSforest). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0022351 parietal serous membrane http://purl.obolibrary.org/obo/UBERON_0004923 organ component layer Serous membrane layer that lines to a body cavity. http://purl.obolibrary.org/obo/CLM_5007970 Scrg1, Grm2 (NSforest). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5007971 Gldc, Pvalb (NSforest). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0022355 basal layer of endometrium http://purl.obolibrary.org/obo/UBERON_0004811 endometrium epithelium The layer of endometrial epithelium adjacent to the uterine cavity. http://purl.obolibrary.org/obo/CLM_5007973 Pcp2, Arhgef33 (NSforest). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0022356 outer layer of endometrium http://purl.obolibrary.org/obo/UBERON_0004811 endometrium epithelium The layer of endometrial epithelium adjacent to the myometrium. http://purl.obolibrary.org/obo/CLM_5007974 Gabra6, Cbln3 (NSforest). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0022358 placenta blood vessel http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure A blood vessel of the placenta. http://purl.obolibrary.org/obo/CLM_5007976 Gdf10, Dao (NSforest). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0022360 male mammary gland duct http://purl.obolibrary.org/obo/UBERON_0001765 mammary duct A mammary gland duct that is part of a male organism. This structure typically regresses. http://purl.obolibrary.org/obo/CLM_5007977 Hsd11b1, Cyp26b1, Mlc1 (NSforest). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0022361 lung field http://purl.obolibrary.org/obo/UBERON_0007688 anlage A specific region of the foregut into the area in which the lung will develop. http://purl.obolibrary.org/obo/CLM_5007980 Islr, Gldc (NSforest). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0023879 neural system http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision A set of neural structures that subserve a specific function, e.g., visual system. http://purl.obolibrary.org/obo/CLM_5007982 Gpr50, S100a6 (NSforest). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5007983 Ccdc153, Tmem212 (NSforest). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0023934 olfactory bulb main glomerular layer http://purl.obolibrary.org/obo/UBERON_0005377 olfactory bulb glomerular layer The glomerular layer of the main olfactory bulb, lying deep to the olfactory nerve layer. It contains the glomeruli, neuropil rich spheroid structures surrounded by a distinctive shell of small neuros and glial cells (Paxinos, the Rat Nervous System, 2nd ed., Academic Press, 1995). http://purl.obolibrary.org/obo/CLM_5007984 Spp2, Mlc1 (NSforest). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0024045 white matter of the cerebellar cortex http://purl.obolibrary.org/obo/UBERON_0019291 white matter of metencephalon White matter that lies deep to the granular cell layer of the cerebellar cortex. It contains afferents to the cerebellar cortex and axons that run between the cerebellar cortex and the deep cerebellar nuclei. http://purl.obolibrary.org/obo/CLM_5007986 Gpr17, Pdgfra (NSforest). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5007987 Fa2h, Cldn11 (NSforest). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0024090 chemoarchitectural part of brain http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain Regional part of an anatomical region that is revealed by the use of a stain that reveals chemoarchitecture. http://purl.obolibrary.org/obo/CLM_5007989 Prg4 (NSforest). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0025525 motor system http://purl.obolibrary.org/obo/UBERON_0023879 neural system The part of the central nervous system that is involved with movement. http://purl.obolibrary.org/obo/CLM_5007995 F13a1, Pf4 (NSforest). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5016781 Rftn1,Iltifb (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0025533 proprioceptive system http://purl.obolibrary.org/obo/UBERON_0023879 neural system The sensory system for the sense of proprioception. http://purl.obolibrary.org/obo/CLM_5016786 Gm20754 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0027368 matrix compartment http://purl.obolibrary.org/obo/UBERON_0025736 chemoarchitectural part of striatum The larger of two chemoarchitectural compartments identified in the neostriatum through differential staining for various biochemical markers. It usually is identified through differentially high staining for acetylcholinesterase and calbinin D28K. http://purl.obolibrary.org/obo/CLM_5016788 Zfp385c,Tfap2b (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0027371 striosome http://purl.obolibrary.org/obo/UBERON_0025736 chemoarchitectural part of striatum One of two compartments identified in the neostriatum, particularly the caudate nucleus, on the basis of differential staining for several biochemical markers such as acetylcholinesterase and calbindin. In individual sections, the striosomes appear as small patches of differentially high or low staining activity. In three dimensions, they form a 3D labyrinth extending throughout the caudate nucleus and in the putamen. http://purl.obolibrary.org/obo/CLM_5016789 Pax2,Spns2 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5016793 Pcdh7,Grin2a,St6gal1 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0029001 matrix compartment of caudate nucleus http://purl.obolibrary.org/obo/UBERON_0027368 matrix compartment Matrix compartment located in the caudate nucleus. http://purl.obolibrary.org/obo/CLM_5016801 Myoc (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5016803 Brinp3,Hsd11b1,Grin2c (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0034705 developing neuroepithelium http://purl.obolibrary.org/obo/UBERON_0000483 epithelium An embryonic or larval epithelium that is committed to form part of the nervous system. http://purl.obolibrary.org/obo/CLM_5016805 Sfrp1,Meis2,Retreg1 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0034706 proliferating neuroepithelium http://purl.obolibrary.org/obo/UBERON_0034705 developing neuroepithelium An epithelium that is undergoing proliferation to provide large numbers of neuronal cells. http://purl.obolibrary.org/obo/CLM_5016806 Greb1 4 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5016808 C230072F16Rik (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0034707 differentiating neuroepithelium http://purl.obolibrary.org/obo/UBERON_0034705 developing neuroepithelium A neuroepithelium some of whose cells are undergoing terminal differentiation to become neuronal cells. http://purl.obolibrary.org/obo/CLM_5016812 Lpl 4 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0034711 cortical preplate http://purl.obolibrary.org/obo/UBERON_0014950 layer of developing cerebral cortex The layer of the developing cerebral cortex that is formed from the first cohort of neurons to migrate out of the cortical ventricular zone; split by the second wave into marginal zone and subplate. http://purl.obolibrary.org/obo/CLM_5016813 Grid1,Nkx2-4 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5016818 Ttr (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0034713 cranial neuron projection bundle http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure Any of the cranial nerves, or their central nervous system analogs (the optic tract, the epiphyseal tract). These analogs are not true nerves, and are instead evaginated sensory afferents emanating from the brain. http://purl.obolibrary.org/obo/CLM_5016821 Bmp4 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0034714 epiphyseal tract http://purl.obolibrary.org/obo/UBERON_0034713 cranial neuron projection bundle A cranial nerve fiber tract that innervates the parietal eye. http://purl.obolibrary.org/obo/CLM_5016823 Cxcl12,2210011C24Rik (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0034715 pineal tract http://purl.obolibrary.org/obo/UBERON_0034714 epiphyseal tract A cranial nerve fiber tract that innervates the pineal body. http://purl.obolibrary.org/obo/CLM_5016824 Efhd1,Spock3 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5019534 Gnrh1 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0034717 integumental taste bud http://purl.obolibrary.org/obo/UBERON_0001727 taste bud A taste bud that is located external to the digestive tube, on the head or body, as found in species such as goldfish. http://purl.obolibrary.org/obo/CLM_5022155 Ly6d (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0034719 lip taste bud http://purl.obolibrary.org/obo/UBERON_0013765 digestive system element A taste bud that is located on a lip. http://purl.obolibrary.org/obo/CLM_5022177 Dao,Efemp1 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0034720 head taste bud http://purl.obolibrary.org/obo/UBERON_0034717 integumental taste bud A taste bud that is located on the skin of the head. http://purl.obolibrary.org/obo/CLM_5022180 Nuf2,Shroom3 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0034721 pharyngeal taste bud http://purl.obolibrary.org/obo/UBERON_0013765 digestive system element A taste bud that is located in the pharynx. http://purl.obolibrary.org/obo/CLM_5022181 Six3os1 2 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0034722 mouth roof taste bud http://purl.obolibrary.org/obo/UBERON_0001727 taste bud A taste bud that is located on the roof of the mouth. http://purl.obolibrary.org/obo/CLM_5022182 Kcnk10,C4b (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0034724 esophageal taste bud http://purl.obolibrary.org/obo/UBERON_0013765 digestive system element A taste bud that is located in the esophagus. http://purl.obolibrary.org/obo/CLM_5022183 Mecom,Prelp (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022186 Fam227b,Shroom3 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0034726 trunk taste bud http://purl.obolibrary.org/obo/UBERON_0034717 integumental taste bud A taste bud that is located on the skin of the trunk. http://purl.obolibrary.org/obo/CLM_5022187 Gm30524 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0034728 autonomic nerve http://purl.obolibrary.org/obo/UBERON_0011779 nerve of head region The autonomic nerve is a small nerve which carries postganglionic sympathetic and parasympathetic neurons from the zygomaticotemporal nerve; a branch of the maxillary nerve, to the lacrimal nerve; a branch of the ophthalmic nerve. These neurons derive from the superior cervical ganglion and the pterygopalatine ganglion respectively. They will travel to the lacrimal gland via the lacrimal nerve. Parasympathetic will induce lacrimation and vice versa. http://purl.obolibrary.org/obo/CLM_5022188 Myoc,Kcne1l,Alpk1 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022190 Myoc,Lncpint (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0034763 hindbrain commissure http://purl.obolibrary.org/obo/UBERON_0005970 brain commissure Any commissure within the hindbrain. http://purl.obolibrary.org/obo/CLM_5022191 Myoc,Jph4,Alpk1 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0034768 morphological feature http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure A part of an organism or organ that is continuous with its surroundings and distinguished from its surroundings based on morphology. http://purl.obolibrary.org/obo/CLM_5022193 Mcm6 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022194 Cxcl5,Kif5a (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0034873 bodily gas http://purl.obolibrary.org/obo/UBERON_0000463 organism substance Any substance in the body or expelled from the body that is in a gaseous state. http://purl.obolibrary.org/obo/CLM_5022195 Fam163a,Nr2f1,Kcnq1ot1 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0034874 air in respiratory system http://purl.obolibrary.org/obo/UBERON_0034947 gas in respiratory system Any portion of gas located in a part of the respiratory system that is composed primarily of air. http://purl.obolibrary.org/obo/CLM_5022196 Zic4 2 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0034876 future neurohypophysis http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure The outgrowth of neuroectoderm located on the floor of the embryonic hypothalamus that gives rise to the neurohypophysis (posterior lobe) of the pituitary gland. http://purl.obolibrary.org/obo/CLM_5022197 Crym,Gabbr2 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0034878 prechordal mesoderm http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure The area of axial mesoderm that develops into the prechordal plate. http://purl.obolibrary.org/obo/CLM_5022198 Gm29683 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022199 Hs3st3a1,Sfrp1 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0034901 cervical sympathetic nerve trunk http://purl.obolibrary.org/obo/UBERON_0004295 sympathetic nerve trunk The cervical ganglia are paravertebral ganglia of the sympathetic nervous system. These emerging postganglionic nerves synapse with preganglionic nerves from the thoracic spinal cord. They consist of three paravertebral ganglia: superior cervical ganglion middle cervical ganglion inferior cervical ganglion. The inferior ganglion may be fused with the first thoracic ganglion to form a single structure, the stellate ganglion. Nerves emerging from cervical sympathetic ganglia contribute to the cardiac plexus, among other things. http://purl.obolibrary.org/obo/CLM_5022200 Adamts18 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022201 Greb1,Il33 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0034903 left atrium endocardium http://purl.obolibrary.org/obo/UBERON_0002166 endocardium of atrium Endocardium that is part of the left atrium. http://purl.obolibrary.org/obo/CLM_5022202 Stk32a 3 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022205 Ecrg4 2 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0034907 pineal parenchyma http://purl.obolibrary.org/obo/UBERON_0005158 parenchyma of central nervous system Parenchymal tissue that forms the pineal gland. http://purl.obolibrary.org/obo/CLM_5022206 Sfrp1,Aqp4 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022215 Mylk3 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0034908 scapular muscle http://purl.obolibrary.org/obo/UBERON_0014892 skeletal muscle organ, vertebrate Any of the muscles that are responsible for moving the scapula. In humans these are the levator scapulae, the infraspinatus muscle, the teres major, the teres minor, and the supraspinatus muscle. http://purl.obolibrary.org/obo/CLM_5022216 Mroh5 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0034921 multi organ part structure http://purl.obolibrary.org/obo/UBERON_0010000 multicellular anatomical structure An multicellular anatomical structure that has subparts of multiple organs as a part. http://purl.obolibrary.org/obo/CLM_5022217 Dscaml1,P3h2 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0034922 cell cluster http://purl.obolibrary.org/obo/UBERON_0010000 multicellular anatomical structure A cluster of cells, largely surrounded by a morphological boundary. http://purl.obolibrary.org/obo/CLM_5022220 Ecrg4 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022233 Sspo,Wfdc2 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0034923 disconnected anatomical group http://purl.obolibrary.org/obo/UBERON_0000465 material anatomical entity Material anatomical entity consisting of multiple anatomical structures that are not connected to each other. http://purl.obolibrary.org/obo/CLM_5022234 Tbc1d1 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0034925 anatomical collection http://purl.obolibrary.org/obo/UBERON_0000465 material anatomical entity A collection of anatomical structures that are alike in terms of their morphology or developmental origin. http://purl.obolibrary.org/obo/CLM_5022236 Neil3,Foxg1 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0034926 anatomical row http://purl.obolibrary.org/obo/UBERON_0034925 anatomical collection An anatomical collection that is arranged in a line. http://purl.obolibrary.org/obo/CLM_5022238 Mms22l,Foxg1,Top2a (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0034929 external soft tissue zone http://purl.obolibrary.org/obo/UBERON_0010314 structure with developmental contribution from neural crest A region or zone on the surface of an organism that encompasses skin and any adnexa, down through muscles and bounded by underlying skeletal support structures. http://purl.obolibrary.org/obo/CLM_5022240 Rmi2,Col27a1 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022242 Rgcc,Plpp4 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0034932 epithelium of biliary system http://purl.obolibrary.org/obo/UBERON_0000483 epithelium The epithelial layer covering the biliary system. This includes the epithelium of the gallbladder (when present) as well as the intrahepatic and extrahepatic bile ducts. http://purl.obolibrary.org/obo/CLM_5022243 Rgcc,9130019P16Rik (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_0034933 layer of smooth muscle tissue http://purl.obolibrary.org/obo/UBERON_0018260 layer of muscle tissue Any organ component layer that consists of smooth muscle tissue. http://purl.obolibrary.org/obo/CLM_5022245 Bmp4,Mob3b (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_1000004 collection of hair on external ear http://purl.obolibrary.org/obo/UBERON_0014382 collection of hairs on head or neck A collection of hairs that grows on the external ear. http://purl.obolibrary.org/obo/CLM_5022246 Vwc2,Opalin (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022247 Bmp4,Cck,Ptger1 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_1000021 skin of face http://purl.obolibrary.org/obo/UBERON_0001084 skin of head A zone of skin that is part of the face. http://purl.obolibrary.org/obo/CLM_5022249 Dbx2,Rassf10 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_1000023 spleen pulp http://purl.obolibrary.org/obo/UBERON_0000064 organ part The parenchyma of the spleen, consisting of lymphocytes and macrophages. It lies between the splenic trabecula. Red pulp is the part suffused with blood and white pulp consists of areas of lymphatic tissue where there are sleeves of lymphocytes and macrophages. http://purl.obolibrary.org/obo/CLM_5022250 Rgs16,Rhbdl2 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_1000024 parenchyma of spleen http://purl.obolibrary.org/obo/UBERON_0000353 parenchyma A parenchyma that is part of a spleen. http://purl.obolibrary.org/obo/CLM_5022251 Il23a,Opalin,Ptprb (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_2000120 lateral line ganglion http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure Ganglion that develops from a cranial ectodermal placode and contains sensory neurons that innervate a lateral line. http://purl.obolibrary.org/obo/CLM_5022252 Cxcl12,Efhd1 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022253 Il23a,Ppp1r14a (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_2000175 posterior lateral line nerve http://purl.obolibrary.org/obo/UBERON_0008906 lateral line nerve Cranial nerve which enters the brain between cranial nerves VIII and IX; contains afferents and sensory efferents to the posterior lateral line ganglion and middle ganglion. Fibers from the posterior lateral line ganglion innervate the occipital dorsal lateral line and trunk lateral lines. http://purl.obolibrary.org/obo/CLM_5022255 Spock3,Rhoj (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022258 Sspo,Selenop (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_2000425 anterior lateral line nerve http://purl.obolibrary.org/obo/UBERON_0008906 lateral line nerve Cranial nerve which enters the brain between cranial nerves VI and VII; contains afferents and sensory efferents to the anterior lateral line ganglia. http://purl.obolibrary.org/obo/CLM_5022259 Adamts12 4 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_2000940 posterior lateral line neuromast http://purl.obolibrary.org/obo/UBERON_0008904 neuromast Neuromast that is part of the posterior lateral line. Kimmel et al, 1995. (Also see Anatomical Atlas entry for lateral line by T. Whitfield.). http://purl.obolibrary.org/obo/CLM_5022260 Gdpd4,Cldn5 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_2001157 posterior lateral line primordium http://purl.obolibrary.org/obo/UBERON_2000228 lateral line primordium A migrating group of cells originating from the posterior lateral line placode. The primordium deposits seven to nine neuromasts and interneuromasts between them during its posterior migration to the tail. Gompel et al, 2001. http://purl.obolibrary.org/obo/CLM_5022262 Rasgef1c (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022264 Dapl1 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_2001269 regenerating fin/limb http://purl.obolibrary.org/obo/UBERON_0007567 regenerating anatomical structure Fin or limb undergoing the process of regeneration. http://purl.obolibrary.org/obo/CLM_5022283 Mrc1,Pf4 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_2001314 posterior lateral line ganglion http://purl.obolibrary.org/obo/UBERON_2000120 lateral line ganglion The posterior lateral line ganglion develops from a cranial ectodermal placode and contains sensory neurons that innervate the posterior lateral line system. http://purl.obolibrary.org/obo/CLM_5022284 Fos (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_2001316 anterior lateral line placode http://purl.obolibrary.org/obo/UBERON_0003067 dorsolateral placode Dorsolateral placode that gives rise to the anterior lateral line. http://purl.obolibrary.org/obo/CLM_5024421 Gpr17, Bmp4, Neu4, Fyn (CAS evidence). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5024422 Tcf7l2, Klk6, Cemip2, Casr (CAS evidence). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_2001389 regeneration epithelium of fin/limb http://purl.obolibrary.org/obo/UBERON_0000483 epithelium An epithelium that is part of a regenerating fin/limb. http://purl.obolibrary.org/obo/CLM_5024424 Klk6 (CAS evidence). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_2001391 anterior lateral line ganglion http://purl.obolibrary.org/obo/UBERON_2000120 lateral line ganglion The anteror lateral line ganglia develops from cranial ectodermal placodes and contain sensory neurons that innervate the anterior lateral line system. http://purl.obolibrary.org/obo/CLM_5029176 Crx, Gngt1, Tph1, Asmt, Gngt2 (CAS evidence). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_2001457 postcranial axial cartilage http://purl.obolibrary.org/obo/UBERON_0007844 cartilage element Cartilage which is part of the axial skeleton. http://purl.obolibrary.org/obo/CLM_5029833 Sspo (CAS evidence). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_2001468 anterior lateral line system http://purl.obolibrary.org/obo/UBERON_0002540 lateral line system The anterior lateral line system develops from cranial ectodermal placodes, situated between the eye and the ear, that give rise to both the neuromasts and the anterior lateral line sensory nerves that innervate the neuromasts. The anterior lateral line system consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head of all fishes and most amphibians and are innervated by several lateral line nerves, which project to the hindbrain. The anterior lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the fish through the water, as well as facilitating shoaling, prey capture, and predator and obstacle avoidance. http://purl.obolibrary.org/obo/CLM_5022235 Slc17a8 7 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5001603 Cldn11,Sec14l5,9630013A20Rik (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_2001470 anterior lateral line http://purl.obolibrary.org/obo/UBERON_0010202 lateral line The anterior lateral line consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head of all fishes and most amphibians. The anterior lateral line develops from cranial ectodermal placodes situated between the eye and ear. http://purl.obolibrary.org/obo/CLM_5000359 Gja1,Lhx2,Gpc5,Nr2f1 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5007043 Slc47a1,Pde11a (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_2001471 posterior lateral line system http://purl.obolibrary.org/obo/UBERON_0002540 lateral line system The posterior lateral line system develops from cranial ectodermal placodes, situated behind the ear, that give rise to both the neuromasts and the posterior lateral line sensory nerves that innervate the neuromasts. The posterior lateral line system consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head of all fishes and most amphibians. The neuromasts are innervated by several lateral line nerves, which project primarily to the hindbrain. The posterior mechanosensory lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the fish through the water, as well as facilitating shoaling, prey capture, and predator and obstacle avoidance. http://purl.obolibrary.org/obo/CLM_5022192 Clstn2 2 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5007985 2900040C04Rik (NSforest). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_2001472 anterior lateral line neuromast http://purl.obolibrary.org/obo/UBERON_0008904 neuromast Neuromast that is part of the anterior lateral line. Kimmel et al, 1995. (Also see Anatomical Atlas entry for lateral line by T. Whitfield.). http://purl.obolibrary.org/obo/CLM_5006983 Aqp4,Hs3st3a1,Slc25a34,C4b (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5001598 2900040C04Rik (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_2005117 anterior lateral line primordium http://purl.obolibrary.org/obo/UBERON_2000228 lateral line primordium A migrating group of cells originating from an anterior lateral line placode. The primordium deposits neuromasts and interneuromasts between them during its migration. http://purl.obolibrary.org/obo/CLM_5022176 Gpr37l1,Ctxn3 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5000362 Gpr50,Apoe (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_2005260 fenestrated capillary http://purl.obolibrary.org/obo/UBERON_0004638 blood vessel endothelium Capillary that has pores in the endothelial cells (60-80 nm in diameter) that are spanned by a diaphragm of radially oriented fibrils and allow small molecules and limited amounts of protein to diffuse. http://purl.obolibrary.org/obo/CLM_5022256 Art3 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5006984 S1pr1,Chrdl1,Sfrp1,Atp13a4 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_2007013 preplacodal ectoderm http://purl.obolibrary.org/obo/UBERON_0005497 non-neural ectoderm Non neural ectoderm that surrounds the presumptive neural plate and gives rise to neurogenic placodes. http://purl.obolibrary.org/obo/CLM_5007969 Inhba, Tfap2b (NSforest). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5006986 S1pr1,6530411M01Rik,Sfrp1,Aqp4 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_3000961 external integument structure http://purl.obolibrary.org/obo/UBERON_0003102 surface structure Structures of the dermis, epidermis, glands and pigment cells recognizable on the external surfaces of the integument. http://purl.obolibrary.org/obo/CLM_5007979 Mfge8, Htra1, Fam107a (NSforest). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5000349 Bmp6,Slc6a5,Zic1,Shisa9,Rgs6 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_3000972 head external integument structure http://purl.obolibrary.org/obo/UBERON_3000961 external integument structure Dermal, epidermal, glandular and pigment structures of the external head integument. http://purl.obolibrary.org/obo/CLM_5001576 Sln,Lmx1a (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022239 Col27a1 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_3000977 body external integument structure http://purl.obolibrary.org/obo/UBERON_3000961 external integument structure Dermal, epidermal, glandular and pigment structures of the body integument. http://purl.obolibrary.org/obo/UBERON_3000981 limb external integument structure http://purl.obolibrary.org/obo/UBERON_3000961 external integument structure Dermal, epidermal, glandular and pigment structures of the limb integument. http://purl.obolibrary.org/obo/CLM_5016825 Aqp1,Foxd3 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_3000982 tail external integument structure http://purl.obolibrary.org/obo/UBERON_3000961 external integument structure Dermal, epidermal, glandular and pigment structures of the tail integument. http://purl.obolibrary.org/obo/UBERON_3010200 vasculature of respiratory integument http://purl.obolibrary.org/obo/UBERON_0003504 respiratory system blood vessel Blood vessels in respiratory skin. http://purl.obolibrary.org/obo/CLM_5021576 Cngb3,Ush2a (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_4000013 mineralized skeletal tissue http://purl.obolibrary.org/obo/UBERON_0004755 skeletal tissue Skeletal tissue that is mineralized. http://purl.obolibrary.org/obo/CLM_5000370 Apod,Slc6a13 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_4000020 mineralized extracellular matrix http://purl.obolibrary.org/obo/UBERON_0000479 tissue Extracellular matrix that is mineralized. http://purl.obolibrary.org/obo/UBERON_4000115 mineralized bone tissue http://purl.obolibrary.org/obo/UBERON_4000013 mineralized skeletal tissue Bone tissue mineralized with hydroxyapatite. http://purl.obolibrary.org/obo/CLM_5006982 Aqp4,Prss23,Stk32a (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_4000118 cellular bone tissue http://purl.obolibrary.org/obo/UBERON_4000115 mineralized bone tissue Mineralized bone tissue that always includes non-terminally differentiated osteoblasts and osteocytes. http://purl.obolibrary.org/obo/UBERON_4100000 skeletal element projection http://purl.obolibrary.org/obo/UBERON_0004529 anatomical projection Anatomical projection that is composed of bone or cartilage tissue. http://purl.obolibrary.org/obo/CLM_5022241 Cenpa (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_4200230 surface of bone http://purl.obolibrary.org/obo/UBERON_0006984 anatomical surface An anatomical surface that is part of a bone. http://purl.obolibrary.org/obo/UBERON_5001466 pedal digit plus metapodial segment http://purl.obolibrary.org/obo/UBERON_5002544 digit plus metapodial segment A subdivision of the autopod consisting of pedal digit plus the region incorporating a single metapodial element. These segments are typically repeated along the pre-axiom to post-axial axis. http://purl.obolibrary.org/obo/CLM_5006966 Slc7a10,Cyp26b1,Igfbp2,Shroom3 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_5002389 manual digit plus metapodial segment http://purl.obolibrary.org/obo/UBERON_5002544 digit plus metapodial segment A subdivision of the autopod consisting of manual digit plus the region incorporating a single metapodial element. These segments are typically repeated along the pre-axiom to post-axial axis. http://purl.obolibrary.org/obo/UBERON_5002544 digit plus metapodial segment http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision A subdivision of the autopod consisting of digit plus the region incorporating a single metapodial element. These segments are typically repeated along the pre-axiom to post-axial axis. http://purl.obolibrary.org/obo/CLM_5001592 Cnmd,Lpl (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_5101466 pedal digit digitopodial skeleton http://purl.obolibrary.org/obo/UBERON_5102544 individual digit of digitopodial skeleton A subdivision of the skeleton of the autopod consisting of the phalanges of pedal digit plus the associated metapodial element. http://purl.obolibrary.org/obo/UBERON_5102389 manual digit digitopodial skeleton http://purl.obolibrary.org/obo/UBERON_5102544 individual digit of digitopodial skeleton A subdivision of the skeleton of the autopod consisting of the phalanges of manual digit plus the associated metapodial element. http://purl.obolibrary.org/obo/CLM_5001585 Gja1,Thbs4,Kcnk10,Pak1 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/UBERON_5102544 individual digit of digitopodial skeleton http://purl.obolibrary.org/obo/UBERON_0010712 limb skeleton subdivision A subdivision of the skeleton of the autopod consisting of the phalanges of a single digit plus the associated metapodial element. http://purl.obolibrary.org/obo/PR_000003450 B-cell lymphoma 6 protein http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human BCL6 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/CLM_5006958 Gfap,Galnt15,Agt (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/PR_000003455 nuclear receptor ROR-gamma isoform 2 http://purl.obolibrary.org/obo/PR_000001902 nuclear receptor ROR-gamma A nuclear receptor ROR-gamma that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P51450-2 or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000003457 V(D)J recombination-activating protein 1 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human RAG1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/CLM_5006963 Dao,Mecom,Fbln5,Prelp (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/PR_000003460 V(D)J recombination-activating protein 2 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human RAG2 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000003463 eomesodermin http://purl.obolibrary.org/obo/PR_000003506 T-brain transcription factor A T-brain transcription factor that is a translation product of the human EOMES gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/CLM_5022184 Fzd2,Gria2,Ttll3 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/PR_000003469 early growth response protein 2 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human EGR2 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000003472 granzyme K http://purl.obolibrary.org/obo/PR_000003505 leukocyte granule-associated proteinase A leukocyte granule-associated proteinase that is a translation product of the human GZMK gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/CLM_5000102 Adora2a,Phactr1,Pcp4l1 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/PR_000003490 granzyme H http://purl.obolibrary.org/obo/PR_000003505 leukocyte granule-associated proteinase A leukocyte granule-associated proteinase that is a translation product of the human GZMH gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/CLM_5006979 S1pr1,Thbs4,Hs3st3a1,Sfrp1 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/PR_000003499 granzyme B http://purl.obolibrary.org/obo/PR_000003505 leukocyte granule-associated proteinase A leukocyte granule-associated proteinase that is a translation product of the human GZMB gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000003505 leukocyte granule-associated proteinase http://purl.obolibrary.org/obo/PR_000027795 trypsin A trypsin that is a serine protease of the granules from mast cells, cytotoxic T lymphocytes and/or natural killer cells. Leukocyte granule-associated proteinase is a component of the immune system that protect higher organisms against viral infection and cellular transformation. Members of this class have features that are strongly conserved including: consensus sequences at their N-termini and around the three catalytic residues, activation from zymogenic forms, and conserved disulphide bridges. http://purl.obolibrary.org/obo/CLM_5006935 Ly6d,Kit (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/PR_000003506 T-brain transcription factor http://purl.obolibrary.org/obo/PR_000000001 protein A protein that contains one copy of the T-box domain (Pfam:PF00907) and it is involved in the anterior neural specification. http://purl.obolibrary.org/obo/PR_000003516 lactosylceramide 4-alpha-galactosyltransferase http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human A4GALT gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/CLM_5007027 9630013A20Rik,Bmp4,Cck,Ptger1 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/PR_000003675 actin, aortic smooth muscle http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human ACTA2 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000003846 agouti-related protein http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human AGRP gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/CLM_5006962 Agt,Prss35,C4b (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/PR_000004528 tyrosine-protein kinase receptor UFO http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human AXL gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000004621 BAG family molecular chaperone regulator 3 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human BAG3 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/CLM_5016794 Cntn3 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/PR_000004691 B-cell lymphoma/leukemia 11B http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human BCL11B gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000004724 bestrophin-4 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human BEST4 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/CLM_5007978 Agt, Aldh1a1, Mlc1 (NSforest). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/PR_000004919 carbonic anhydrase 3 http://purl.obolibrary.org/obo/PR_000025841 single domain alpha-type carbonic anhydrase A single domain alpha-type carbonic anhydrase that is a translation product of the human CA3 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000004968 calretinin http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CALB2 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/CLM_5016783 Cdh22 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/PR_000004973 calcitonin gene-related peptide type 1 receptor http://purl.obolibrary.org/obo/PR_000044637 calcitonin receptor protein A calcitonin receptor protein that is a translation product of the human CALCRL gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000004984 calreticulin http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CALR gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/NCBITaxon_9481 Callithrix http://purl.obolibrary.org/obo/NCBITaxon_9480 Callitrichinae http://purl.obolibrary.org/obo/PR_000005110 cholecystokinin http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CCK gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000005178 CD9 molecule http://purl.obolibrary.org/obo/PR_000001403 tetraspanin A tetraspanin that is a translation product of the human CD9 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0036303 vasculature of central nervous system http://purl.obolibrary.org/obo/UBERON_0036302 vasculature of central nervous system plus retina http://purl.obolibrary.org/obo/PR_000005307 CCAAT/enhancer-binding protein alpha http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CEBPA gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/NCBITaxon_34346 Schizosaccharomycetales http://purl.obolibrary.org/obo/NCBITaxon_147554 Schizosaccharomycetes http://purl.obolibrary.org/obo/PR_000005310 CCAAT/enhancer-binding protein epsilon http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CEBPE gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000005404 choline O-acetyltransferase http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CHAT gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/NCBITaxon_9986 Oryctolagus cuniculus http://purl.obolibrary.org/obo/NCBITaxon_9984 Oryctolagus http://purl.obolibrary.org/obo/PR_000005444 chondrolectin http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CHODL gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000005460 neuronal acetylcholine receptor subunit alpha-7 http://purl.obolibrary.org/obo/PR_000044668 nicotinic acetylcholine receptor protein A nicotinic acetylcholine receptor protein that is a translation product of the human CHRNA7 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0037447 wall of male urethra http://purl.obolibrary.org/obo/UBERON_0036521 wall of urethra http://purl.obolibrary.org/obo/PR_000005693 collagen alpha-1(X) chain http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human COL10A1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0037455 wall of female urethra http://purl.obolibrary.org/obo/UBERON_0036521 wall of urethra http://purl.obolibrary.org/obo/PR_000005694 collagen alpha-1(XI) chain http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human COL11A1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000006169 cell surface glycoprotein CD200 receptor 3 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the mouse Cd200r3 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0036654 wall of lateral ventricle http://purl.obolibrary.org/obo/UBERON_0036661 wall of ventricular system of brain http://purl.obolibrary.org/obo/PR_000006172 CD209 molecule-like protein B http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the mouse Cd209b gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000006294 dopamine beta-hydroxylase http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human DBH gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0036656 wall of third ventricle http://purl.obolibrary.org/obo/UBERON_0036661 wall of ventricular system of brain http://purl.obolibrary.org/obo/PR_000006611 DNA nucleotidylexotransferase http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human DNTT gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/UBERON_0036657 wall of fourth ventricle http://purl.obolibrary.org/obo/UBERON_0036661 wall of ventricular system of brain http://purl.obolibrary.org/obo/PR_000006646 dipeptidase 1 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human DPEP1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000006897 endothelin-1 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human EDN1 gene or a 1:1 ortholog thereof. https://purl.brain-bican.org/ontology/mbao/MBA_623 Cerebral nuclei http://purl.obolibrary.org/obo/UBERON_8440012 cerebral nuclei http://purl.obolibrary.org/obo/PR_000007152 eosinophil peroxidase http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human EPX gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000007204 estrogen receptor http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human ESR1 gene or a 1:1 ortholog thereof. https://purl.brain-bican.org/ontology/dhbao/DHBA_10331 cerebral nuclei http://purl.obolibrary.org/obo/UBERON_8440012 cerebral nuclei http://purl.obolibrary.org/obo/PR_000007431 high affinity immunoglobulin epsilon receptor subunit alpha http://purl.obolibrary.org/obo/PR_000001355 immunoglobulin gamma Fc receptor II/III/IV An immunoglobulin gamma Fc receptor II/III/IV that is a translation product of the human FCER1A gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000007479 fibroblast growth factor 1 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human FGF1 gene or a 1:1 ortholog thereof. https://purl.brain-bican.org/ontology/mbao/MBA_278 Striatum-like amygdalar nuclei http://purl.obolibrary.org/obo/UBERON_8440030 striatum-like amygdalar nuclei http://purl.obolibrary.org/obo/PR_000007489 fibroblast growth factor 2 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human FGF2 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000007498 fibroblast growth factor 7 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human FGF7 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/NCBITaxon_9605 Homo http://purl.obolibrary.org/obo/NCBITaxon_207598 Homininae http://purl.obolibrary.org/obo/PR_000007499 fibroblast growth factor 8 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human FGF8 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000007597 protein c-Fos http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human FOS gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/NCBITaxon_9479 Platyrrhini http://purl.obolibrary.org/obo/NCBITaxon_314293 Simiiformes http://purl.obolibrary.org/obo/PR_000007636 forkhead box protein N1 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human FOXN1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000007643 forkhead box protein P1 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human FOXP1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/NCBITaxon_9526 Catarrhini http://purl.obolibrary.org/obo/NCBITaxon_314293 Simiiformes http://purl.obolibrary.org/obo/PR_000007806 galanin http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human GAL gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/NCBITaxon_9604 Hominidae http://purl.obolibrary.org/obo/NCBITaxon_314295 Hominoidea http://purl.obolibrary.org/obo/PR_000007857 erythroid transcription factor http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human GATA1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000007858 endothelial transcription factor GATA-2 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human GATA2 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/NCBITaxon_379583 Feliformia http://purl.obolibrary.org/obo/NCBITaxon_33554 Carnivora http://purl.obolibrary.org/obo/PR_000007939 glial fibrillary acidic protein http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human GFAP gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000008457 beta-globin http://purl.obolibrary.org/obo/PR_000050467 hemoglobin subunit A hemoglobin subunit that is a translation product of the human HBB gene, a 1:1 ortholog thereof, or pro-orthologs thereof. http://purl.obolibrary.org/obo/NCBITaxon_314293 Simiiformes http://purl.obolibrary.org/obo/NCBITaxon_376913 Haplorrhini http://purl.obolibrary.org/obo/PR_000008467 hemoglobin subunit zeta http://purl.obolibrary.org/obo/PR_000050467 hemoglobin subunit A hemoglobin subunit that is a translation product of the human HBZ gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/NCBITaxon_9681 Felidae http://purl.obolibrary.org/obo/NCBITaxon_379583 Feliformia http://purl.obolibrary.org/obo/PR_000008857 hemoglobin subunit beta-1 http://purl.obolibrary.org/obo/PR_000008457 beta-globin A beta-globin that is a translation product of the mouse Hbb-b1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000025841 single domain alpha-type carbonic anhydrase http://purl.obolibrary.org/obo/PR_000000001 protein A protein that contains a single copy of the Eukaryotic-type carbonic anhydrase domain (Pfam:PF00194) with no other conserved domains. http://purl.obolibrary.org/obo/NCBITaxon_6243 Rhabditidae http://purl.obolibrary.org/obo/NCBITaxon_55879 Rhabditoidea http://purl.obolibrary.org/obo/PR_000029968 somatotropin hormone family member http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a standalone version of the Hormone_1 domain (Pfam:PF00103). In the immature form, the domain is preceded by a signal peptide. http://purl.obolibrary.org/obo/PR_000028527 casein derived peptide http://purl.obolibrary.org/obo/PR_000018264 proteolytic cleavage product A proteolytic cleavage product that is derived from any of the casein milk proteins. http://purl.obolibrary.org/obo/NCBITaxon_6237 Caenorhabditis http://purl.obolibrary.org/obo/NCBITaxon_55885 Peloderinae http://purl.obolibrary.org/obo/PR_000029562 iroquois-class homeodomain protein IRX-6 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human IRX6 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/NCBITaxon_55885 Peloderinae http://purl.obolibrary.org/obo/NCBITaxon_6243 Rhabditidae http://purl.obolibrary.org/obo/PR_000030026 CALCA gene translation product (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A CALCA gene translation product that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_000032148 lysosome-associated membrane glycoprotein 5 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human LAMP5 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/NCBITaxon_376913 Haplorrhini http://purl.obolibrary.org/obo/NCBITaxon_9443 Primates http://purl.obolibrary.org/obo/PR_000032533 LIM/homeobox protein Lhx6 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human LHX6 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000032708 piezo-type mechanosensitive ion channel component 2 http://purl.obolibrary.org/obo/PR_000044682 piezo channel protein A piezo channel protein that is a translation product of the human PIEZO2 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/NCBITaxon_9498 Cebidae http://purl.obolibrary.org/obo/NCBITaxon_9479 Platyrrhini http://purl.obolibrary.org/obo/PR_000034294 lymphocyte antigen 75 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A lymphocyte antigen 75 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P01730 T-cell surface glycoprotein CD4 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A CD4 molecule that is encoded in the genome of human. http://purl.obolibrary.org/obo/NCBITaxon_314295 Hominoidea http://purl.obolibrary.org/obo/NCBITaxon_9526 Catarrhini http://purl.obolibrary.org/obo/PR_P08514 integrin alpha-IIb (human) http://purl.obolibrary.org/obo/PR_000009127 integrin alpha-IIb An integrin alpha-IIb that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_Q01196 runt-related transcription factor 1 (human) http://purl.obolibrary.org/obo/PR_000014362 runt-related transcription factor 1 A runt-related transcription factor 1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/NCBITaxon_207598 Homininae http://purl.obolibrary.org/obo/NCBITaxon_9604 Hominidae http://purl.obolibrary.org/obo/PR_O88713 killer cell lectin-like receptor subfamily G member 1 (mouse) http://purl.obolibrary.org/obo/PR_000009426 killer cell lectin-like receptor subfamily G member 1 A killer cell lectin-like receptor subfamily G member 1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_O88875 CD160 antigen (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A CD160 molecule that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/NCBITaxon_9788 Equidae http://purl.obolibrary.org/obo/NCBITaxon_9787 Perissodactyla http://purl.obolibrary.org/obo/PR_O89103 complement component C1q receptor (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A complement component C1q receptor that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_O95343 homeobox protein SIX3 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A homeobox protein SIX3 that is encoded in the genome of human. http://purl.obolibrary.org/obo/NCBITaxon_9789 Equus http://purl.obolibrary.org/obo/NCBITaxon_9788 Equidae http://purl.obolibrary.org/obo/PR_O95936 eomesodermin homolog (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein An eomesodermin that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_O95971 CD160 antigen (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A CD160 molecule that is encoded in the genome of human. http://purl.obolibrary.org/obo/NCBITaxon_9979 Leporidae http://purl.obolibrary.org/obo/NCBITaxon_9975 Lagomorpha http://purl.obolibrary.org/obo/PR_P01101 protein c-Fos (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A protein c-Fos that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P01189 pro-opiomelanocortin (human) http://purl.obolibrary.org/obo/PR_000013015 pro-opiomelanocortin A pro-opiomelanocortin that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0035606 cartilage of external acoustic meatus http://purl.obolibrary.org/obo/UBERON_0034944 zone of organ http://purl.obolibrary.org/obo/PR_P01193 pro-opiomelanocortin (mouse) http://purl.obolibrary.org/obo/PR_000013015 pro-opiomelanocortin A pro-opiomelanocortin that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P01210 proenkephalin-A (human) http://purl.obolibrary.org/obo/PR_000012544 proenkephalin-A A proenkephalin-A that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0034996 outer renal medulla loop of Henle http://purl.obolibrary.org/obo/UBERON_0034997 renal medulla loop of Henle http://purl.obolibrary.org/obo/PR_P01213 proenkephalin-B (human) http://purl.obolibrary.org/obo/PR_000012526 proenkephalin-B A proenkephalin-B that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P01282 VIP peptides (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A VIP peptides that is encoded in the genome of human. http://purl.obolibrary.org/obo/NCBITaxon_9483 Callithrix jacchus http://purl.obolibrary.org/obo/NCBITaxon_1965096 Callithrix http://purl.obolibrary.org/obo/PR_P01303 pro-neuropeptide Y (human) http://purl.obolibrary.org/obo/PR_000011387 neuropeptide Y A neuropeptide Y that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P01590 interleukin-2 receptor subunit alpha (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein An interleukin-2 receptor subunit alpha that is encoded in the genome of mouse. https://purl.brain-bican.org/ontology/mbao/MBA_219 Somatomotor areas, Layer 2/3 http://purl.obolibrary.org/obo/UBERON_8440000 cortical layer II/III http://purl.obolibrary.org/obo/PR_P01731 T-cell surface glycoprotein CD8 alpha chain (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A T-cell surface glycoprotein CD8 alpha chain that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P01732-1 T-cell surface glycoprotein CD8 alpha chain isoform 1 (human) http://purl.obolibrary.org/obo/PR_P01732 T-cell surface glycoprotein CD8 alpha chain (human) A T-cell surface glycoprotein CD8 alpha chain isoform 1 that is encoded in the genome of human. https://purl.brain-bican.org/ontology/mbao/MBA_947 Somatomotor areas, Layer 6b http://purl.obolibrary.org/obo/UBERON_8440003 cortical layer VIb http://purl.obolibrary.org/obo/PR_P01831 Thy-1 membrane glycoprotein (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A Thy-1 membrane glycoprotein that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P01903 HLA class II histocompatibility antigen, DR alpha chain (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein An MHC class II histocompatibility antigen alpha chain DRA that is encoded in the genome of human. https://purl.brain-bican.org/ontology/mbao/MBA_10687 Paraflocculus, granular layer https://purl.brain-bican.org/ontology/mbao/MBA_1143 Cerebellar cortex, granular layer http://purl.obolibrary.org/obo/PR_P02008 hemoglobin subunit zeta (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A hemoglobin subunit zeta that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P02088 hemoglobin subunit beta-1 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A hemoglobin subunit beta-1 that is encoded in the genome of mouse. https://purl.brain-bican.org/ontology/mbao/MBA_10690 Flocculus, granular layer https://purl.brain-bican.org/ontology/mbao/MBA_1143 Cerebellar cortex, granular layer http://purl.obolibrary.org/obo/PR_P02724 glycophorin-A (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A glycophorin-A that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P03995 glial fibrillary acidic protein (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A glial fibrillary acidic protein that is encoded in the genome of mouse. https://purl.brain-bican.org/ontology/mbao/MBA_10735 Nodulus (X), granular layer https://purl.brain-bican.org/ontology/mbao/MBA_1143 Cerebellar cortex, granular layer http://purl.obolibrary.org/obo/PR_P04000 long-wave-sensitive opsin 1 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A long-wave-sensitive opsin 1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P04001 medium-wave-sensitive opsin 1 (human) http://purl.obolibrary.org/obo/PR_000050522 medium-wave-sensitive opsin (human) A medium-wave-sensitive opsin (human) that is a translation product of the OPN1MW gene in human. https://purl.brain-bican.org/ontology/mbao/MBA_10689 Paraflocculus, molecular layer https://purl.brain-bican.org/ontology/mbao/MBA_1144 Cerebellar cortex, molecular layer http://purl.obolibrary.org/obo/PR_P04053 DNA nucleotidylexotransferase (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A DNA nucleotidylexotransferase that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P04216 Thy-1 membrane glycoprotein (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A Thy-1 membrane glycoprotein that is encoded in the genome of human. https://purl.brain-bican.org/ontology/mbao/MBA_10737 Nodulus (X), molecular layer https://purl.brain-bican.org/ontology/mbao/MBA_1144 Cerebellar cortex, molecular layer http://purl.obolibrary.org/obo/PR_P0DN77 medium-wave-sensitive opsin 2 (human) http://purl.obolibrary.org/obo/PR_000050522 medium-wave-sensitive opsin (human) A medium-wave-sensitive opsin (human) that is a translation product of the OPN1MW2 gene in human. http://purl.obolibrary.org/obo/PR_P05089 arginase-1 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein An arginase-1 that is encoded in the genome of human. https://purl.brain-bican.org/ontology/mbao/MBA_10692 Flocculus, molecular layer https://purl.brain-bican.org/ontology/mbao/MBA_1144 Cerebellar cortex, molecular layer http://purl.obolibrary.org/obo/PR_P05164 myeloperoxidase (human) http://purl.obolibrary.org/obo/PR_000010543 myeloperoxidase A myeloperoxidase that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P05230 fibroblast growth factor 1 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A fibroblast growth factor 1 that is encoded in the genome of human. https://purl.brain-bican.org/ontology/mbao/MBA_10688 Paraflocculus, Purkinje layer https://purl.brain-bican.org/ontology/mbao/MBA_1145 Cerebellar cortex, Purkinje layer http://purl.obolibrary.org/obo/PR_P05305 endothelin-1 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein An endothelin-1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P05532 mast/stem cell growth factor receptor Kit (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A mast/stem cell growth factor receptor that is encoded in the genome of mouse. https://purl.brain-bican.org/ontology/mbao/MBA_10691 Flocculus, Purkinje layer https://purl.brain-bican.org/ontology/mbao/MBA_1145 Cerebellar cortex, Purkinje layer http://purl.obolibrary.org/obo/PR_P05533 lymphocyte antigen 6A-2/6E-1 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A lymphocyte antigen 6A-2/6E-1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P05555 integrin alpha-M (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein An integrin alpha-M that is encoded in the genome of mouse. https://purl.brain-bican.org/ontology/mbao/MBA_10736 Nodulus (X), Purkinje layer https://purl.brain-bican.org/ontology/mbao/MBA_1145 Cerebellar cortex, Purkinje layer http://purl.obolibrary.org/obo/PR_P06127 T-cell surface glycoprotein CD5 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A T-cell surface glycoprotein CD5 that is encoded in the genome of human. http://purl.obolibrary.org/obo/NCBITaxon_1965096 Callithrix http://purl.obolibrary.org/obo/NCBITaxon_9481 Callithrix http://purl.obolibrary.org/obo/PR_P06332 T-cell surface glycoprotein CD4 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A CD4 molecule that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P06467 hemoglobin subunit zeta (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A hemoglobin subunit zeta that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/NCBITaxon_9984 Oryctolagus http://purl.obolibrary.org/obo/NCBITaxon_9979 Leporidae http://purl.obolibrary.org/obo/CL_0700009 obsolete kidney collecting duct beta-intercalated cell OBSOLETE. A renal beta-intercalated cell that is part of the cortical collecting duct. The medullary collecting duct does not contain the renal beta-intercalated cell type. http://purl.obolibrary.org/obo/PR_P06734 low affinity immunoglobulin epsilon Fc receptor (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A low affinity immunoglobulin epsilon Fc receptor that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P06800 receptor-type tyrosine-protein phosphatase C (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A receptor-type tyrosine-protein phosphatase C that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/GO_0002288 obsolete NK T cell activation involved in immune response OBSOLETE. The change in morphology and behavior of a mature or immature natural killer T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response. http://purl.obolibrary.org/obo/PR_P06876 transcriptional activator Myb (mouse) http://purl.obolibrary.org/obo/PR_000010799 myb proto-oncogene protein A myb proto-oncogene protein that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P06879 prolactin (mouse) http://purl.obolibrary.org/obo/PR_000013246 prolactin A prolactin that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/GO_0003674 molecular_function A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs. http://purl.obolibrary.org/obo/PR_P06881-1 calcitonin gene-related peptide 1 (human) http://purl.obolibrary.org/obo/PR_000027226 calcitonin gene-related peptide 1 A calcitonin gene-related peptide 1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/GO_0008150 biological_process A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence. http://purl.obolibrary.org/obo/PR_P07359 platelet glycoprotein Ib alpha chain (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A platelet glycoprotein Ib alpha chain that is encoded in the genome of human. http://purl.obolibrary.org/obo/GO_0044237 obsolete cellular metabolic process OBSOLETE. The chemical reactions and pathways by which individual cells transform chemical substances. http://purl.obolibrary.org/obo/PR_P08071 lactotransferrin (mouse) http://purl.obolibrary.org/obo/PR_000009978 lactotransferrin A lactotransferrin that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P08101 low affinity immunoglobulin gamma Fc region receptor II (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A low affinity immunoglobulin gamma Fc region receptor II that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/GO_0098537 obsolete lobed nucleus OBSOLETE. Nucleus with two or more lobes connected by a thin filament that contains no internal chromatin. Examples include the nuclei of mature basophils, eosinophils and neutrophils in mice and humans. http://purl.obolibrary.org/obo/PR_P08121 collagen alpha-1(III) chain (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A collagen alpha-1(III) chain that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P08152 E3 SUMO-protein ligase EGR2 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein An early growth response protein 2 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P08508 low affinity immunoglobulin gamma Fc region receptor III (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A low affinity immunoglobulin gamma Fc region receptor III that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_000001338 complement receptor type 2 A protein that is a translation product of the human CR2 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_P08571 monocyte differentiation antigen CD14 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A CD14 molecule that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P08920 T-cell surface antigen CD2 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A CD2 molecule that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_000001808 C/C-C motif small inducible chemokine A protein with core architecture consisting of a Small cytokines (intecrine/chemokine), interleukin-8 like (Pfam:PF00048) domain. http://purl.obolibrary.org/obo/PR_P09038 fibroblast growth factor 2 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A fibroblast growth factor 2 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P09172 dopamine beta-hydroxylase (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A dopamine beta-hydroxylase that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_000001971 vascular endothelial growth factor receptor A protein with core architecture consisting of a signal sequence, followed by 7 Ig-like domains (Pfam:PF00047, Pfam:PF07679, or Pfam:PF07686), a transmembrane region, and a cytoplasmic Protein tyrosine kinase domain. http://purl.obolibrary.org/obo/PR_P09240 cholecystokinin (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A cholecystokinin that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P09326 CD48 antigen (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A CD48 molecule that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_000018263 amino acid chain A molecule that consists of amino acid residues (unmodified amino-acid residues and/or modified amino-acid residues) linked by peptide bonds or derivatives of such bonds. http://purl.obolibrary.org/obo/PR_P09382 galectin-1 (human) http://purl.obolibrary.org/obo/PR_000009766 galectin-1 A galectin-1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P09564 T-cell antigen CD7 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A CD7 molecule that is encoded in the genome of human. http://purl.obolibrary.org/obo/RO_0002577 system A material entity consisting of multiple components that are causally integrated. http://purl.obolibrary.org/obo/PR_P09793 cytotoxic T-lymphocyte protein 4 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A cytotoxic T-lymphocyte protein 4 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P09803 cadherin-1 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A cadherin-1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/GO_0070999 obsolete detection of mechanical stimulus involved in sensory perception of gravity OBSOLETE. The series of events involved in the perception of gravity in which a sensory mechanical stimulus is received and converted into a molecular signal. http://purl.obolibrary.org/obo/PR_P09838 DNA nucleotidylexotransferase (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A DNA nucleotidylexotransferase that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_000010543 myeloperoxidase A protein that is a translation product of the human MPO gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_P33766 fMet-Leu-Phe receptor (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein An fMet-Leu-Phe receptor that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P34810 macrosialin (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A macrosialin that is encoded in the genome of human. http://purl.obolibrary.org/obo/CL_4023067 obsolete Martinotti morphology L2/3 pvalb-like sst GABAergic cortical interneuron (Mus musculus) OBSOLETE A L2/3 pvalb-like sst GABAergic cortical interneuron (Mus musculus) that has Martinotti morphology. http://purl.obolibrary.org/obo/PR_P35329 B-cell receptor CD22 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A B-cell receptor CD22 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P35343 C-X-C chemokine receptor type 2 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A C-X-C chemokine receptor type 2 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/CL_4023100 obsolete L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (Homo sapiens) OBSOLETE. An intratelencephalic-projecting glutamatergic neuron with a soma found in layer 6 of the human primary motor cortex. http://purl.obolibrary.org/obo/PR_P35456 urokinase plasminogen activator surface receptor (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A urokinase plasminogen activator surface receptor that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P35461 lymphocyte antigen 6G (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A lymphocyte antigen 6G that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/CL_2000009 obsolete microvascular endothelium blood vessel endothelial cell Any blood vessel endothelial cell that is part of a microvascular endothelium. http://purl.obolibrary.org/obo/PR_P35546 proto-oncogene tyrosine-protein kinase receptor Ret (mouse) http://purl.obolibrary.org/obo/PR_000013895 proto-oncogene tyrosine-protein kinase receptor Ret A proto-oncogene tyrosine-protein kinase receptor Ret that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P35918 vascular endothelial growth factor receptor 2 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A vascular endothelial growth factor receptor 2 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/CL_2000026 obsolete cerebellum Golgi cell Any Golgi cell that is part of a cerebellum. http://purl.obolibrary.org/obo/PR_P36363 fibroblast growth factor 7 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A fibroblast growth factor 7 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P37217 early activation antigen CD69 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A CD69 molecule that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/CL_2000050 obsolete retina retinal ganglion cell Any retinal ganglion cell that is part of a retina. http://purl.obolibrary.org/obo/PR_P37237 fibroblast growth factor 8 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A fibroblast growth factor 8 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P40240 CD9 antigen (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A CD9 molecule that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/CL_2000082 obsolete melanocyte of foreskin OBSOLETE. Any melanocyte of skin that is part of a skin of prepuce of penis. http://purl.obolibrary.org/obo/PR_P41182 B-cell lymphoma 6 protein (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A B-cell lymphoma 6 protein that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P41183 B-cell lymphoma 6 protein homolog (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A B-cell lymphoma 6 protein that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/CL_4023034 obsolete L2/3 pvalb-like sst GABAergic cortical interneuron (Mus musculus) OBSOLETE A sst GABAergic cortical interneuron transcriptomically between the sst and the pvalb families with a soma found in L2/3. Some L2/3 PV-like sst cells have Martinotti morphology while some have basket cell morphology. L2/3 PV-like sst cells have lower AP width and higher firing rate than typical Sst subclass cells. L2/3 PV-like sst cells have high maximum firing rate variability, with many classified as belonging to the pvalb subclass on the basis of electrophysiology. http://purl.obolibrary.org/obo/PR_P41219 peripherin (human) http://purl.obolibrary.org/obo/PR_000013289 peripherin A peripherin that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P41272 CD27 antigen (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A CD27 molecule that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/CL_0017501 obsolete lobed nucleus Nucleus with two or more lobes connected by a thin filament that contains no internal chromatin. http://purl.obolibrary.org/obo/PR_P41539 protachykinin-1 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A protachykinin-1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P41597 C-C chemokine receptor type 2 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A C-C chemokine receptor type 2 that is encoded in the genome of human. http://purl.obolibrary.org/obo/CL_4023099 obsolete L5 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (Homo sapiens) OBSOLETE. An intratelencephalic-projecting glutamatergic neuron with a soma found in layer 5 of the human primary motor cortex. http://purl.obolibrary.org/obo/PR_P42082 T-lymphocyte activation antigen CD86 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A CD86 molecule that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P43235 cathepsin K (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A cathepsin K that is encoded in the genome of human. http://purl.obolibrary.org/obo/CL_4023101 obsolete L5/6 near-projecting glutamatergic neuron of the primary motor cortex (Homo sapiens) OBSOLETE. A near-projecting glutamatergic neuron with a soma found in layer 5/6 of the human primary motor cortex. http://purl.obolibrary.org/obo/PR_P43699 homeobox protein Nkx-2.1 (human) http://purl.obolibrary.org/obo/PR_000011241 homeobox protein Nkx-2.1 A homeobox protein Nkx-2.1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/CL_4023102 obsolete L5/6 near-projecting glutamatergic neuron of the primary motor cortex (Callithrix jacchus) OBSOLETE. A near-projecting glutamatergic neuron with a soma found in layer 5/6 of the marmoset primary motor cortex. http://purl.obolibrary.org/obo/PR_P47212 galanin peptides (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A galanin that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P47774 C-C chemokine receptor type 7 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A C-C chemokine receptor type 7 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/CL_4023103 obsolete L2/3 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (Callithrix jacchus) OBSOLETE. An intratelencephalic-projecting glutamatergic neuron with a soma found in layer 2/3 of the marmoset primary motor cortex. http://purl.obolibrary.org/obo/PR_P97797 tyrosine-protein phosphatase non-receptor type substrate 1 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A tyrosine-protein phosphatase non-receptor type substrate 1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P97926 oxytocin receptor (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein An oxytocin receptor that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/CL_4023104 obsolete L5 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (Callithrix jacchus) OBSOLETE An intratelencephalic-projecting glutamatergic neuron with a soma found in layer 5 of the marmoset primary motor cortex. http://purl.obolibrary.org/obo/PR_Q00342 receptor-type tyrosine-protein kinase FLT3 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A receptor-type tyrosine-protein kinase FLT3 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q00609 T-lymphocyte activation antigen CD80 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A CD80 molecule that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/CL_4023105 obsolete L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (Callithrix jacchus) OBSOLETE. An intratelencephalic-projecting glutamatergic neuron with a soma found in layer 6 of the marmoset primary motor cortex. http://purl.obolibrary.org/obo/PR_Q00651 integrin alpha-4 (mouse) http://purl.obolibrary.org/obo/PR_000009129 integrin alpha-4 An integrin alpha-4 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q00993 tyrosine-protein kinase receptor UFO (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A tyrosine-protein kinase receptor UFO that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/CL_4023106 obsolete meis2 expressing cortical GABAergic cell (Callithrix jacchus) OBSOLETE. A mouse GABAergic cell located in the marmoset cerebral cortex that expresses meis2. http://purl.obolibrary.org/obo/PR_Q01102 P-selectin (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A P-selectin that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q01151 CD83 antigen (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A CD83 molecule that is encoded in the genome of human. http://purl.obolibrary.org/obo/CL_4023070 obsolete caudal ganglionic eminence derived GABAergic cortical interneuron OBSOLETE. A GABAergic cortical interneuron that develops from the caudal ganglionic eminence and has migrated to the cerebral cortex. http://purl.obolibrary.org/obo/PR_Q01851 POU domain, class 4, transcription factor 1 (human) http://purl.obolibrary.org/obo/PR_000013041 POU domain, class 4, transcription factor 1 A POU domain, class 4, transcription factor 1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_Q02242 programmed cell death protein 1 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A programmed cell death protein 1 that is encoded in the genome of mouse. https://purl.brain-bican.org/ontology/mbao/MBA_339 Midbrain, sensory related http://purl.obolibrary.org/obo/PR_Q02548 paired box protein Pax-5 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A paired box protein PAX-5 that is encoded in the genome of human. https://purl.brain-bican.org/ontology/mbao/MBA_987 Pons, motor related http://purl.obolibrary.org/obo/PR_Q02650 paired box protein Pax-5 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A paired box protein PAX-5 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q03059 choline O-acetyltransferase (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A choline O-acetyltransferase that is encoded in the genome of mouse. http://identifiers.org/ncbigene/268780 Egflam (Mmus) http://purl.obolibrary.org/obo/PR_Q03347 runt-related transcription factor 1 (mouse) http://purl.obolibrary.org/obo/PR_000014362 runt-related transcription factor 1 A runt-related transcription factor 1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q04683 C-X-C chemokine receptor type 5 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A C-X-C chemokine receptor type 5 that is encoded in the genome of mouse. http://identifiers.org/ncbigene/319903 9630013A20Rik (Mmus) http://purl.obolibrary.org/obo/PR_Q04857 collagen alpha-1(VI) chain (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A collagen alpha-1(VI) chain that is encoded in the genome of mouse. http://identifiers.org/ncbigene/16590 Kit (Mmus) http://purl.obolibrary.org/obo/PR_Q05117 tartrate-resistant acid phosphatase type 5 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A tartrate-resistant acid phosphatase type 5 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q05306 collagen alpha-1(X) chain (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A collagen alpha-1(X) chain that is encoded in the genome of mouse. http://identifiers.org/ncbigene/212377 Mms22l (Mmus) http://purl.obolibrary.org/obo/PR_Q06318 uteroglobin (mouse) http://purl.obolibrary.org/obo/PR_000014505 uteroglobin A uteroglobin that is encoded in the genome of mouse. http://identifiers.org/ncbigene/67791 6530411M01Rik (Mmus) http://purl.obolibrary.org/obo/PR_Q07075 glutamyl aminopeptidase (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A glutamyl aminopeptidase that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_Q07108 early activation antigen CD69 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A CD69 molecule that is encoded in the genome of human. https://purl.brain-bican.org/ontology/mbao/MBA_1080 Hippocampal region http://purl.obolibrary.org/obo/PR_Q07763 natural killer cell receptor 2B4 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A natural killer cell receptor 2B4 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q08331 calretinin (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A calretinin that is encoded in the genome of mouse. https://purl.brain-bican.org/ontology/mbao/MBA_244 Main olfactory bulb, outer plexiform layer http://purl.obolibrary.org/obo/PR_Q08857 platelet glycoprotein 4 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A platelet glycoprotein 4 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q10589 bone marrow stromal antigen 2 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A bone marrow stromal antigen 2 that is encoded in the genome of human. https://purl.brain-bican.org/ontology/mbao/MBA_258 Lateral septal nucleus, rostral (rostroventral) part http://purl.obolibrary.org/obo/PR_Q11127 alpha-(1,3)-fucosyltransferase 4 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein An alpha-(1,3)-fucosyltransferase 4 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q6UVY6 DBH-like monooxygenase protein 1 (human) http://purl.obolibrary.org/obo/PR_000010529 DBH-like monooxygenase protein 1 A DBH-like monooxygenase protein 1 that is encoded in the genome of human. https://purl.brain-bican.org/ontology/mbao/MBA_484682516 corpus callosum, body http://purl.obolibrary.org/obo/PR_Q6Y4S4 metastasis-suppressor KiSS-1 (mouse) http://purl.obolibrary.org/obo/PR_000009344 metastasis-suppressor KiSS-1 A metastasis-suppressor KiSS-1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q704Y3 transient receptor potential cation channel subfamily V member 1 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A transient receptor potential cation channel TRPV1 that is encoded in the genome of mouse. https://purl.brain-bican.org/ontology/mbao/MBA_956 corpus callosum, anterior forceps http://purl.obolibrary.org/obo/PR_Q8R2Q8 bone marrow stromal antigen 2 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A bone marrow stromal antigen 2 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q8R4G0 netrin-G1 (mouse) http://purl.obolibrary.org/obo/PR_000011467 netrin-G1 A netrin-G1 that is encoded in the genome of mouse. http://identifiers.org/ncbigene/66240 Kcne1l (Mmus) http://purl.obolibrary.org/obo/PR_Q8R4I7 neuropilin and tolloid-like protein 1 (mouse) http://purl.obolibrary.org/obo/PR_000011143 neuropilin and tolloid-like protein 1 A neuropilin and tolloid-like protein 1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q8TDF5 neuropilin and tolloid-like protein 1 (human) http://purl.obolibrary.org/obo/PR_000011143 neuropilin and tolloid-like protein 1 A neuropilin and tolloid-like protein 1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/CP_0000000 obsolete CP:0000000 http://purl.obolibrary.org/obo/PR_Q8VBX4 C-type lectin domain family 4 member K (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A C-type lectin domain family 4 member K that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q8VCC9 spondin-1 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A spondin-1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/CP_0000027 obsolete CP:0000027 http://purl.obolibrary.org/obo/PR_Q9CW73 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q96E93 killer cell lectin-like receptor subfamily G member 1 (human) http://purl.obolibrary.org/obo/PR_000009426 killer cell lectin-like receptor subfamily G member 1 A killer cell lectin-like receptor subfamily G member 1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/CP_0000028 obsolete CP:0000028 http://purl.obolibrary.org/obo/PR_Q9ER75 iroquois-class homeodomain protein IRX-6 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein An iroquois-class homeodomain protein IRX-6 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q9NNX6 CD209 antigen (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A CD209 molecule that is encoded in the genome of human. http://purl.obolibrary.org/obo/CP_0000035 obsolete CP:0000035 http://purl.obolibrary.org/obo/PR_Q9NPC4 lactosylceramide 4-alpha-galactosyltransferase (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A lactosylceramide 4-alpha-galactosyltransferase that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_Q9NPY3 complement component C1q receptor (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A complement component C1q receptor that is encoded in the genome of human. http://purl.obolibrary.org/obo/CP_0000037 obsolete CP:0000037 http://purl.obolibrary.org/obo/PR_Q9P2U8 vesicular glutamate transporter 2 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A vesicular glutamate transporter 2 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_Q9QUM0 integrin alpha-IIb (mouse) http://purl.obolibrary.org/obo/PR_000009127 integrin alpha-IIb An integrin alpha-IIb that is encoded in the genome of mouse. http://identifiers.org/ncbigene/14560 Gdf10 (Mmus) http://purl.obolibrary.org/obo/PR_Q9QUM4 signaling lymphocytic activation molecule (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A SLAM family member 1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q9WTK5 nuclear factor NF-kappa-B p100 subunit (mouse) http://purl.obolibrary.org/obo/PR_000011178 nuclear factor NF-kappa-B p100 subunit A nuclear factor NF-kappa-B p100 subunit that is encoded in the genome of mouse. https://purl.brain-bican.org/ontology/mbao/MBA_983 lateral forebrain bundle system http://purl.obolibrary.org/obo/PR_Q9WTR1 transient receptor potential cation channel subfamily V member 2 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A transient receptor potential cation channel TRPV2 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q9WVS0 inducible T-cell costimulator (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein An inducible T-cell costimulator that is encoded in the genome of mouse. http://identifiers.org/ncbigene/333564 Fndc3c1 (Mmus) http://purl.obolibrary.org/obo/STATO_0000184 ratio http://purl.obolibrary.org/obo/STATO_0000039 statistic A ratio is a data item which is formed with two numbers r and s is written r/s, where r is the numerator and s is the denominator. The ratio of r to s is equivalent to the quotient r/s. http://purl.obolibrary.org/obo/UBERON_0034945 excreted gas http://purl.obolibrary.org/obo/UBERON_0034873 bodily gas Any gaseous product of an excretory process. https://purl.brain-bican.org/ontology/mbao/MBA_991 medial forebrain bundle system http://purl.obolibrary.org/obo/UBERON_0034946 gas excreted from digestive tract http://purl.obolibrary.org/obo/UBERON_0034945 excreted gas Any excreted gas that is produced by the digestive tract. http://purl.obolibrary.org/obo/UBERON_0035550 superficial vein http://purl.obolibrary.org/obo/UBERON_0001638 vein Any of the veins carrying deoxygenated blood from the subcutaneous tissue layers. http://identifiers.org/ncbigene/22774 Zic4 (Mmus) http://purl.obolibrary.org/obo/STATO_0000039 statistic http://purl.obolibrary.org/obo/IAO_0000027 data entity a statistic is a measurement datum to describe a dataset or a variable. It is generated by a calculation on set of observed data. http://purl.obolibrary.org/obo/GO_0061853 regulation of neuroblast migration http://purl.obolibrary.org/obo/GO_0030334 regulation of cell migration Any process that modulates the frequency, rate or extent of neuroblast migration. http://identifiers.org/ncbigene/216892 Spns2 (Mmus) http://purl.obolibrary.org/obo/GO_0061854 positive regulation of neuroblast migration http://purl.obolibrary.org/obo/GO_0030335 positive regulation of cell migration Any process that activates or increases the frequency, rate or extent of neuroblast migration. http://purl.obolibrary.org/obo/GO_0061855 negative regulation of neuroblast migration http://purl.obolibrary.org/obo/GO_0030336 negative regulation of cell migration Any process that stops, prevents, or reduces the frequency, rate or extent of neuroblast migration. http://identifiers.org/ncbigene/241159 Neu4 (Mmus) http://purl.obolibrary.org/obo/GO_0061856 Golgi calcium ion transmembrane transport http://purl.obolibrary.org/obo/GO_0032472 Golgi calcium ion transport A process in which a calcium ion is transported from one side of a Golgi membrane to the other by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/UBERON_0036215 anatomical surface region http://purl.obolibrary.org/obo/UBERON_0000465 material anatomical entity Material anatomical entity that forms the outermost boundary of an anatomical structure. http://identifiers.org/ncbigene/210530 P3h2 (Mmus) http://purl.obolibrary.org/obo/GO_0110020 regulation of actomyosin structure organization http://purl.obolibrary.org/obo/GO_0032956 regulation of actin cytoskeleton organization Any process that modulates the frequency, rate or extent of the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures containing both actin and myosin or paramyosin. http://purl.obolibrary.org/obo/PATO_0045001 normal object quality http://purl.obolibrary.org/obo/PATO_0001241 physical object quality A quality of an object that has a value that is normal or average. http://identifiers.org/ncbigene/13142 Dao (Mmus) http://purl.obolibrary.org/obo/PATO_0045073 normal process quality http://purl.obolibrary.org/obo/PATO_0001236 process quality A quality of a process that has a value that is normal or average. http://identifiers.org/ncbigene/14360 Fyn (Mmus) http://identifiers.org/ncbigene/12424 Cck (Mmus) http://purl.obolibrary.org/obo/PATO_0045016 normal elasticity http://purl.obolibrary.org/obo/PATO_0045001 normal object quality An elasticity which is relatively normal or average. http://identifiers.org/ncbigene/100040736 Foxd2os (Mmus) http://purl.obolibrary.org/obo/PATO_0045011 normal contractility http://purl.obolibrary.org/obo/PATO_0045001 normal object quality A contractility which is relatively normal or average. http://identifiers.org/ncbigene/100042056 9130019P16Rik (Mmus) http://purl.obolibrary.org/obo/PATO_0045009 normal coiling http://purl.obolibrary.org/obo/PATO_0045001 normal object quality A coiling which is normal or average. http://identifiers.org/ncbigene/100043902 Six3os1 (Mmus) http://purl.obolibrary.org/obo/GO_0150034 distal axon http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure That part of an axon close to and including the growth cone or the axon terminus. http://identifiers.org/ncbigene/100503592 A330076C08Rik (Mmus) http://purl.obolibrary.org/obo/GO_0150111 regulation of transepithelial transport http://purl.obolibrary.org/obo/GO_0051049 regulation of transport Any process that modulates the frequency, rate or extent of transepithelial transport. http://identifiers.org/ncbigene/100504234 Ccdc170 (Mmus) http://identifiers.org/ncbigene/101100 Ttll3 (Mmus) http://purl.obolibrary.org/obo/UBERON_8400001 hepatic acinus zone 1 http://purl.obolibrary.org/obo/UBERON_8400005 metabolic zone of liver The region of the hepatic acinus that is closest to the arterial blood supply and has the highest oxygen concentration. Zone 1 is located in the periportal region of the liver lobule, closest to the portal triad. Hepatocytes in this region are primarily involved in oxidative energy metabolism. http://identifiers.org/ncbigene/101772 Ano1 (Mmus) http://identifiers.org/ncbigene/102632457 Gm30524 (Mmus) http://purl.obolibrary.org/obo/UBERON_8400002 hepatic acinus zone 3 http://purl.obolibrary.org/obo/UBERON_8400005 metabolic zone of liver The region of the hepatic acinus immediately surrounding the central veins. This region has the lowest oxygen concentration in the acinus. Zone 3 is located in the centrilobular region of the liver lobule, closest to the central vein. Hepatocytes in this region are the primary location for the biotransformation of drugs. http://identifiers.org/ncbigene/102635243 Gm32633 (Mmus) http://identifiers.org/ncbigene/102638227 Gm34838 (Mmus) http://purl.obolibrary.org/obo/UBERON_8400003 hepatic acinus zone 2 http://purl.obolibrary.org/obo/UBERON_8400005 metabolic zone of liver The region of the hepatic acinus in between zones 1 and 3. Blood in this region has an intermediate oxygen concentration relative to the other two zones of the hepatic acinus. Zone 2 is located in the midzonal region of the liver lobule. Hepatocytes in this region have mixed functionality in comparison with those in zones 1 and 3. http://identifiers.org/ncbigene/103978 Gpc5 (Mmus) http://identifiers.org/ncbigene/104010 Cdh22 (Mmus) http://purl.obolibrary.org/obo/CL_0001072 CD34-negative, CD117-positive innate lymphoid cell, human http://purl.obolibrary.org/obo/CL_0001082 immature innate lymphoid cell An innate lymphoid cell in the human with the phenotype CD34-negative, CD117-positive, and a precusor to NK cells, ILC2 cells, and ILC3 cells. http://identifiers.org/ncbigene/104174 Gldc (Mmus) http://identifiers.org/ncbigene/104245 Slc6a5 (Mmus) http://purl.obolibrary.org/obo/CL_0001073 CD34-negative, CD56-positive, CD117-positive innate lymphoid cell, human http://purl.obolibrary.org/obo/CL_0001072 CD34-negative, CD117-positive innate lymphoid cell, human An innate lymphoid cell in the human with the phenotype CD34-negative, CD56-positive, CD117-positive.Thie cell type may include precusors to NK cells and ILC3 cells. http://identifiers.org/ncbigene/104798 Sfta3-ps (Mmus) http://identifiers.org/ncbigene/107376 E330013P04Rik (Mmus) http://purl.obolibrary.org/obo/CL_0001074 CD34-positive, CD56-positive, CD117-positive common innate lymphoid precursor, human http://purl.obolibrary.org/obo/CL_0001082 immature innate lymphoid cell An innate lymphoid cell precursor in the human with the phenotype CD34-positive, CD56-positive, CD117-positive.Thie cell type may include precusors to NK cells and ILC3 cells. http://identifiers.org/ncbigene/107626 Asmt (Mmus) http://identifiers.org/ncbigene/108000 Cenpf (Mmus) http://purl.obolibrary.org/obo/CL_0001075 KLRG1-positive innate lymphoid cell, human http://purl.obolibrary.org/obo/CL_0001072 CD34-negative, CD117-positive innate lymphoid cell, human An innate lymphoid cell in the human with the phenotype KLRG1-positive that is a precusor for ILC2 cells. http://identifiers.org/ncbigene/108068 Grm2 (Mmus) http://identifiers.org/ncbigene/108069 Grm3 (Mmus) http://purl.obolibrary.org/obo/CL_0001076 NKp46-positive innate lymphoid cell, human http://purl.obolibrary.org/obo/CL_0001074 CD34-positive, CD56-positive, CD117-positive common innate lymphoid precursor, human An innate lymphoid cell in the human with the phenotype NKp46-positive that is a precusor for NK cells and ILC3 cells. http://identifiers.org/ncbigene/108073 Grm7 (Mmus) http://identifiers.org/ncbigene/109272 Mybpc1 (Mmus) http://purl.obolibrary.org/obo/CL_0001077 ILC1, human http://purl.obolibrary.org/obo/CL_0001068 ILC1 An ILC1 cell in the human with the phenotype CD56-negative, IL-7Ralpha-positive, T-bet-positive. http://identifiers.org/ncbigene/109979 Art3 (Mmus) http://identifiers.org/ncbigene/110648 Lmx1a (Mmus) http://purl.obolibrary.org/obo/CL_0001078 group 3 innate lymphoid cell, human http://purl.obolibrary.org/obo/CL_0001071 group 3 innate lymphoid cell A group 3 innate lymphoid cell in the human with the phenotype IL-7Ralpha-positive. http://identifiers.org/ncbigene/110862 Kcnq3 (Mmus) http://purl.obolibrary.org/obo/CL_0001079 NKp44-positive group 3 innate lymphoid cell, human http://purl.obolibrary.org/obo/CL_0001078 group 3 innate lymphoid cell, human A group 3 innate lymphoid cell in the human with the phenotype IL-7Ralpha-positive, and NKp44-positive. http://identifiers.org/ncbigene/114873 Dscaml1 (Mmus) http://identifiers.org/ncbigene/11540 Adora2a (Mmus) http://purl.obolibrary.org/obo/CL_0001080 NKp44-negative group 3 innate lymphoid cell, human http://purl.obolibrary.org/obo/CL_0001078 group 3 innate lymphoid cell, human A group 3 innate lymphoid cell in the human with the phenotype IL-7Ralpha-positive, and NKp44-negative. http://identifiers.org/ncbigene/11606 Agt (Mmus) http://purl.obolibrary.org/obo/CL_0001081 group 2 innate lymphoid cell, human http://purl.obolibrary.org/obo/CL_0001069 group 2 innate lymphoid cell A group 2 innate lymphoid cell in the human with the phenotype CD25-positive, CD127-positive, CD161-positive, and GATA-3-positive. http://identifiers.org/ncbigene/11668 Aldh1a1 (Mmus) http://identifiers.org/ncbigene/11682 Alk (Mmus) http://purl.obolibrary.org/obo/CL_0001082 immature innate lymphoid cell http://purl.obolibrary.org/obo/CL_0001065 innate lymphoid cell An innate lyphoid cell with an immature phenotype. http://identifiers.org/ncbigene/116847 Prelp (Mmus) http://purl.obolibrary.org/obo/CL_0008038 alpha motor neuron http://purl.obolibrary.org/obo/CL_0008039 lower motor neuron A large, multipolar lower motor neuron of the brainstem and spinal cord that innervates the extrafusal muscle fibers of skeletal muscle and are directly responsible for initiating their contraction. While their cell bodies are in the CNS (in the anterior gray horn of the spinal cord), they are part of the somatic nervous system - a branch of the PNS. http://identifiers.org/ncbigene/116849 Iltifb (Mmus) http://identifiers.org/ncbigene/11815 Apod (Mmus) http://purl.obolibrary.org/obo/CL_0008039 lower motor neuron http://purl.obolibrary.org/obo/CL_0005024 somatomotor neuron The motor neurons of vertebrates that directly innervate skeletal muscles. They receive input from upper motor neurons. http://identifiers.org/ncbigene/11816 Apoe (Mmus) http://identifiers.org/ncbigene/11826 Aqp1 (Mmus) http://purl.obolibrary.org/obo/CL_0011026 progenitor cell http://purl.obolibrary.org/obo/CL_0011115 precursor cell A precursor cell that has a tendency to differentiate into a specific type of cell. They are descendants of stem cells, only they are more constrained in their differentiation potential or capacity for self-renewal, and are often more limited in both senses. http://identifiers.org/ncbigene/11829 Aqp4 (Mmus) http://purl.obolibrary.org/obo/CL_0019015 lung parenchyma resident eosinophil http://purl.obolibrary.org/obo/CL_0000774 band form eosinophil An eosinophil with a ring-shaped nucleus that is resident in the lung parenchyma. In mouse, lung parenchyma resident eosinophils are IL-5-independent Siglec-F(intermediate) CD62L+ CD101(low). In human, they are Siglec-8+ CD62L+ IL-3R(low). http://identifiers.org/ncbigene/118446 Gjc3 (Mmus) http://purl.obolibrary.org/obo/CL_0019017 lymphatic vessel smooth muscle cell http://purl.obolibrary.org/obo/CL_0000359 vascular associated smooth muscle cell A smooth muscle cell that is part of any lymphatic vessel. http://identifiers.org/ncbigene/12111 Bgn (Mmus) http://identifiers.org/ncbigene/12159 Bmp4 (Mmus) http://identifiers.org/ncbigene/12161 Bmp6 (Mmus) http://purl.obolibrary.org/obo/CL_0019018 blood vessel smooth muscle cell http://purl.obolibrary.org/obo/CL_0000359 vascular associated smooth muscle cell A smooth muscle cell that is part of any blood vessel. http://identifiers.org/ncbigene/12192 Zfp36l1 (Mmus) http://identifiers.org/ncbigene/12259 C1qa (Mmus) http://purl.obolibrary.org/obo/CL_0019019 tracheobronchial smooth muscle cell http://purl.obolibrary.org/obo/CL_0000192 smooth muscle cell A smooth muscle cell that is part of the tracheobronchial tree. http://identifiers.org/ncbigene/12268 C4b (Mmus) http://purl.obolibrary.org/obo/UBERON_8000009 Purkinje fiber network http://purl.obolibrary.org/obo/UBERON_0018649 cardiac muscle tissue of ventricle A collection of Purkinje fibers that receives signals from the right and left bundle branches and innervates the ventricular cardiac muscle. The Purkinje fiber network creates synchronized contractions of the heart ventricles. http://identifiers.org/ncbigene/12290 Cacna1e (Mmus) http://identifiers.org/ncbigene/12322 Camk2a (Mmus) http://purl.obolibrary.org/obo/UBERON_8400005 metabolic zone of liver http://purl.obolibrary.org/obo/UBERON_0000063 organ subunit Any of the metabolic zones found in the liver. Liver tissue is heterogenous at the level of morphometry and histochemistry. This heterogeneity is linked to the position of a cell within the functional unit of the tissue, which, in turn, is related to the blood supply: cells located in the upstream zone differ from those in the downstream zone with respect to subcellular structures, key enzymes, translocators, and receptors and, therefore, have different metabolic capacities. This is the basis for 'metabolic zonation', a concept first proposed in mammals for carbohydrate metabolism and later expanded to include amino acid and ammonia metabolism, xenobiotic metabolism, protective metabolism, and formation of plasma proteins. http://identifiers.org/ncbigene/12374 Casr (Mmus) http://identifiers.org/ncbigene/12494 Cd38 (Mmus) http://purl.obolibrary.org/obo/UBERON_8400021 liver serosa http://purl.obolibrary.org/obo/UBERON_0000042 serous membrane Hepatic serous coat; peritoneal covering of the liver, enclosing almost all except for a triangular area on its posterior surface (the 'bare area of the liver') and a smaller area where the liver and gallbladder are in direct contact. http://identifiers.org/ncbigene/12550 Cdh1 (Mmus) http://identifiers.org/ncbigene/12615 Cenpa (Mmus) http://purl.obolibrary.org/obo/UBERON_8400023 liver subserosa http://purl.obolibrary.org/obo/UBERON_0012375 subserosa Subserosal tissue of liver. A zone of areolar connective tissue lying beneath the serous coat of the liver and distinguished with difficulty from the fibrous capsule of Glisson. http://identifiers.org/ncbigene/12741 Cldn5 (Mmus) http://identifiers.org/ncbigene/12951 Crx (Mmus) http://purl.obolibrary.org/obo/UBERON_8400024 subcapsular region of liver http://purl.obolibrary.org/obo/UBERON_0001280 liver parenchyma Region of liver parenchyma immediately below the capsule. This region is frequently specified in pathology diagnoses. http://identifiers.org/ncbigene/12971 Crym (Mmus) http://identifiers.org/ncbigene/13176 Dcc (Mmus) http://purl.obolibrary.org/obo/UBERON_8410000 duodeno-jejunal junction http://purl.obolibrary.org/obo/UBERON_8410024 intestinal junction The anatomical junction between the duodenum and the jejunum. http://identifiers.org/ncbigene/13195 Ddc (Mmus) http://identifiers.org/ncbigene/13199 Ddn (Mmus) http://purl.obolibrary.org/obo/UBERON_8410016 descending sigmoid junction http://purl.obolibrary.org/obo/UBERON_8410024 intestinal junction The anatomical junction between the descending colon and the sigmoid colon. http://identifiers.org/ncbigene/13371 Dio2 (Mmus) http://identifiers.org/ncbigene/13411 Dnah11 (Mmus) http://purl.obolibrary.org/obo/UBERON_8410017 left colic vein http://purl.obolibrary.org/obo/UBERON_0002017 portal vein A portal vein that drains the descending colon. It is a tributary of the inferior mesenteric vein, and follows the path of its corresponding artery, the left colic artery. http://identifiers.org/ncbigene/13488 Drd1 (Mmus) http://identifiers.org/ncbigene/13618 Ednrb (Mmus) http://purl.obolibrary.org/obo/UBERON_8410018 right colic vein http://purl.obolibrary.org/obo/UBERON_0002017 portal vein A portal vein that drains the ascending colon. It is a tributary of the superior mesenteric vein, and travels with its corresponding artery, the right colic artery. http://identifiers.org/ncbigene/13649 Egfr (Mmus) http://identifiers.org/ncbigene/13865 Nr2f1 (Mmus) http://purl.obolibrary.org/obo/UBERON_8410019 jejuno-ileal junction http://purl.obolibrary.org/obo/UBERON_8410024 intestinal junction The area where the jejunum ends and the ileum part of the intestine begins. Although there is no clear distinct section, the ileum is narrower and has smaller villi than the jejunum. http://identifiers.org/ncbigene/14013 Mecom (Mmus) http://purl.obolibrary.org/obo/UBERON_8410033 lymph node vein http://purl.obolibrary.org/obo/UBERON_0001638 vein A vein where lymph node venules condense and which exits at the lymph node hilum. It is also called hilar vein. http://identifiers.org/ncbigene/140919 Slc17a6 (Mmus) http://purl.obolibrary.org/obo/UBERON_8410034 lymph node artery http://purl.obolibrary.org/obo/UBERON_0001637 artery An artery that enters the lymph node at the hilum and branches into smaller arterioles. http://identifiers.org/ncbigene/14165 Fgf10 (Mmus) http://identifiers.org/ncbigene/14281 Fos (Mmus) http://purl.obolibrary.org/obo/PATO_0070008 T Martinotti morphology http://purl.obolibrary.org/obo/PATO_0070007 Martinotti morphology A Martinotti cell morphology that inheres in neurons which have axons that form a horizontal ramification, making it T-shaped. http://identifiers.org/ncbigene/14400 Gabrb1 (Mmus) http://identifiers.org/ncbigene/14412 Slc6a13 (Mmus) http://purl.obolibrary.org/obo/PATO_0070002 basket cell morphology http://purl.obolibrary.org/obo/PATO_0070026 multipolar neuron morphology A cell morphology that inheres in multipolar neurons with densely branched terminal axonal arborizations that form basket-like structures surrounding and synapsing to the somas of target cells. http://identifiers.org/ncbigene/14415 Gad1 (Mmus) http://purl.obolibrary.org/obo/PATO_0070003 small basket cell morphology http://purl.obolibrary.org/obo/PATO_0070002 basket cell morphology A basket cell morphology that inheres in neurons with axonal arbors composed of frequent, short, curvy axonal branches that tend to be near their somata and within the same layer. http://identifiers.org/ncbigene/14417 Gad2 (Mmus) http://identifiers.org/ncbigene/14432 Gap43 (Mmus) http://purl.obolibrary.org/obo/PATO_0070004 large basket cell morphology http://purl.obolibrary.org/obo/PATO_0070002 basket cell morphology A basket cell morphology that inheres in neurons that are large, and typically ascend to give rise to many long horizontally and vertically projecting axon collaterals that traverse neighboring columns and can extend through all cortical layers. http://identifiers.org/ncbigene/14609 Gja1 (Mmus) http://purl.obolibrary.org/obo/PATO_0070005 nest basket cell morphology http://purl.obolibrary.org/obo/PATO_0070002 basket cell morphology A basket cell morphology that inheres in neurons which have simpler dendritic arbors (compared to small or large basket cell morphology), and an axonal plexus of intermediate density, composed of a few long, smooth axonal branches. http://identifiers.org/ncbigene/14695 Gnb3 (Mmus) http://identifiers.org/ncbigene/14699 Gngt1 (Mmus) http://purl.obolibrary.org/obo/PATO_0070006 cortical bipolar morphology http://purl.obolibrary.org/obo/PATO_0070027 bitufted dendrite cell morphology A cell morphology that inheres in neurons which have two principal dendrites that emerge from the soma and begin to branch some distance from it, have few spines, and branch in narrow fields. This is in contrast to bitufted morphology where branching occurs close to the soma. http://identifiers.org/ncbigene/14710 Gngt2 (Mmus) http://identifiers.org/ncbigene/14714 Gnrh1 (Mmus) http://purl.obolibrary.org/obo/PATO_0070025 unipolar neuron morphology http://purl.obolibrary.org/obo/PATO_0010006 cell morphology A cell morphology that inheres in neurons with only one process, a neurite, that extends from the cell body. The neurite then branches to form dendritic and axonal processes. http://identifiers.org/ncbigene/14724 Gp1bb (Mmus) http://identifiers.org/ncbigene/14765 Gpr50 (Mmus) http://purl.obolibrary.org/obo/PATO_0070026 multipolar neuron morphology http://purl.obolibrary.org/obo/PATO_0010006 cell morphology A cell morphology that inheres in neurons which possess three or more neurites, usually a single axon and many dendrites and dendritic branches. http://identifiers.org/ncbigene/14799 Gria1 (Mmus) http://identifiers.org/ncbigene/14803 Grid1 (Mmus) http://purl.obolibrary.org/obo/PATO_0070028 extratelencephalic projecting http://purl.obolibrary.org/obo/PATO_0070033 neuron projection quality A neuron projection quality that is a characteristic of neurons whose soma is located in the telencephalon and that project to structures outside the telencephalon http://identifiers.org/ncbigene/14811 Grin2a (Mmus) http://identifiers.org/ncbigene/14813 Grin2c (Mmus) http://purl.obolibrary.org/obo/PATO_0070030 near projecting http://purl.obolibrary.org/obo/PATO_0070033 neuron projection quality A neuron projection quality that is a characteristic of neurons with projections that terminate locally rather than distantly. http://identifiers.org/ncbigene/14870 Gstp1 (Mmus) http://purl.obolibrary.org/obo/PATO_0070033 neuron projection quality http://purl.obolibrary.org/obo/PATO_0001018 physical quality A physical quality inhering in a neuron by virtue of the relative location of its soma and the regions to which it projects and makes synaptic contacts in. http://identifiers.org/ncbigene/15186 Hdc (Mmus) http://identifiers.org/ncbigene/15221 Foxd3 (Mmus) http://purl.obolibrary.org/obo/CL_4023042 L6 corticothalamic-projecting glutamatergic cortical neuron http://purl.obolibrary.org/obo/CL_4023013 corticothalamic-projecting glutamatergic cortical neuron A transcriptomically distinct corticothalamic-projecting neuron with a soma found in cortical layer 6. http://identifiers.org/ncbigene/15228 Foxg1 (Mmus) http://purl.obolibrary.org/obo/GO_0140668 positive regulation of oxytocin production http://purl.obolibrary.org/obo/GO_0010628 positive regulation of gene expression Any process that activates or increases the frequency, rate or extent of production of oxytocin. http://purl.obolibrary.org/obo/CL_0009088 circulating angiogenic cell http://purl.obolibrary.org/obo/CL_0002619 adult endothelial progenitor cell An adult endothelial progenitor cell characterised in vivo by homing to ischemic sites and paracrine support of angiogenesis. These cells do not form colonies. http://identifiers.org/ncbigene/15364 Hmga2 (Mmus) http://identifiers.org/ncbigene/15478 Hs3st3a1 (Mmus) http://purl.obolibrary.org/obo/CL_0009090 endothelial colony forming cell http://purl.obolibrary.org/obo/CL_0002619 adult endothelial progenitor cell An adult endothelial progenitor cell that is resident of adult vasculature and capable of differentiating to regenerate endothelial cell populations. Endothelial colony forming cells are characterised in vivo by clonal proliferative status, de novo vessel formation, homing to ischemic sites and paracrine support of angiogenesis. These cells are phenotypically similar to endothelial cells. http://identifiers.org/ncbigene/15483 Hsd11b1 (Mmus) http://purl.obolibrary.org/obo/CL_0009104 B cell zone reticular cell http://purl.obolibrary.org/obo/CL_0009102 lymph node fibroblastic reticular cell A fibroblastic reticular cell found in the lymph node germinal center dark zone (B cell zone). http://identifiers.org/ncbigene/16008 Igfbp2 (Mmus) http://identifiers.org/ncbigene/16011 Igfbp5 (Mmus) http://purl.obolibrary.org/obo/CL_4023154 myelinating glial cell http://purl.obolibrary.org/obo/CL_0000125 glial cell A glial cell that myelinates axonal processes. http://identifiers.org/ncbigene/16323 Inhba (Mmus) http://identifiers.org/ncbigene/16372 Irx2 (Mmus) http://purl.obolibrary.org/obo/CL_4030018 kidney connecting tubule principal cell http://purl.obolibrary.org/obo/CL_1000768 kidney connecting tubule epithelial cell A renal principal cell located in the connecting tubule. http://identifiers.org/ncbigene/16426 Itih3 (Mmus) http://identifiers.org/ncbigene/16870 Lhx2 (Mmus) http://purl.obolibrary.org/obo/CL_0004247 bistratified cell http://purl.obolibrary.org/obo/CL_2000029 central nervous system neuron A neuron that stratifies dendrites at two and only two locations. http://identifiers.org/ncbigene/16956 Lpl (Mmus) http://identifiers.org/ncbigene/17068 Ly6d (Mmus) http://purl.obolibrary.org/obo/CL_0003046 M13 retinal ganglion cell http://purl.obolibrary.org/obo/CL_0003001 bistratified retinal ganglion cell A bistratifed retinal ganglion cell that has small, symmetric dendritic fields that terminate in S2 and S4. http://identifiers.org/ncbigene/170790 Mlc1 (Mmus) http://purl.obolibrary.org/obo/CL_0004115 retinal ganglion cell B http://purl.obolibrary.org/obo/CL_0000740 retinal ganglion cell A monostratified retinal ganglion cell with small to medium soma and small to medium dendritic field. http://identifiers.org/ncbigene/171211 Edaradd (Mmus) http://identifiers.org/ncbigene/17132 Maf (Mmus) http://purl.obolibrary.org/obo/CL_0004241 WF2 amacrine cell http://purl.obolibrary.org/obo/CL_0004253 wide field retinal amacrine cell An amacrine cell with a wide dendritic field, dendrites in S2, and post-synaptic terminals in S1. http://identifiers.org/ncbigene/171469 Gpr37l1 (Mmus) http://identifiers.org/ncbigene/17155 Man1a (Mmus) http://purl.obolibrary.org/obo/CL_0004216 type 5b cone bipolar cell http://purl.obolibrary.org/obo/CL_0000757 type 5 cone bipolar cell (sensu Mus) A type 5 cone bipolar cell with diffuse axonal branches. http://identifiers.org/ncbigene/17219 Mcm6 (Mmus) http://identifiers.org/ncbigene/17300 Foxc1 (Mmus) http://purl.obolibrary.org/obo/CL_0003023 retinal ganglion cell C6 http://purl.obolibrary.org/obo/CL_0003020 retinal ganglion cell C outer A retinal ganglion cell C outer that has dense dendritic diversity. http://identifiers.org/ncbigene/17304 Mfge8 (Mmus) http://purl.obolibrary.org/obo/CL_0003051 UV cone cell http://purl.obolibrary.org/obo/CL_0000573 retinal cone cell A cone cell that detects ultraviolet (UV) wavelength light. http://identifiers.org/ncbigene/17345 Mki67 (Mmus) http://identifiers.org/ncbigene/17441 Mog (Mmus) http://purl.obolibrary.org/obo/CL_0004242 WF3-1 amacrine cell http://purl.obolibrary.org/obo/CL_0004253 wide field retinal amacrine cell An amacrine cell with a wide dendritic field, dendrites in S3, and post-synaptic terminals in S3. Dendrites of this cell type are straight and minimally branched. http://identifiers.org/ncbigene/17533 Mrc1 (Mmus) http://identifiers.org/ncbigene/17536 Meis2 (Mmus) http://purl.obolibrary.org/obo/CL_0004125 retinal ganglion cell C2 inner http://purl.obolibrary.org/obo/CL_0003024 retinal ganglion cell C inner A retinal ganglion cell C inner that has dense dendritic diversity. http://purl.obolibrary.org/obo/CL_4033016 secondary crest myofibroblast http://purl.obolibrary.org/obo/CL_0000186 myofibroblast cell A myofibroblast that is part of an alveoli during alveolarization. The contractile force of this cell elongates the secondary crest, while producing a framework of elastin and tenascin. During the maturation of the septa, secondary crest myofibroblasts, together with matrix fibroblasts, secrete metalloproteinases and other ECM‐remodeling proteins to thin the septal tip ECM. The secondary crest myofibroblast continues producing elastin, eventually undergoing apoptosis during adulthood. http://identifiers.org/ncbigene/18133 Ccn3 (Mmus) http://identifiers.org/ncbigene/18417 Cldn11 (Mmus) http://purl.obolibrary.org/obo/GO_0160083 exhausted T cell differentiation http://purl.obolibrary.org/obo/GO_0030217 T cell differentiation The process in which an activated T cell acquires specialized features of an exhausted T cell. http://identifiers.org/ncbigene/18424 Otx2 (Mmus) http://identifiers.org/ncbigene/18479 Pak1 (Mmus) http://purl.obolibrary.org/obo/CL_4307030 Astro-NT NN_1 Nuf2 astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301589 Astro-NT NN_1 astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gfap (Mmus), Sfrp5 (Mmus), Cldn10 (Mmus), Riiad1 (Mmus). It is distinguished from other Astro-NT NN_1 cells by expression of Nuf2, Shroom3. These cells are located in the Cerebellum, brain , in or close to the regions: arbor vitae . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5210 Astro-NT NN_1. http://identifiers.org/ncbigene/18488 Cntn3 (Mmus) http://purl.obolibrary.org/obo/GO_0120025 plasma membrane bounded cell projection http://purl.obolibrary.org/obo/GO_0042995 cell projection A prolongation or process extending from a cell and that is bounded by plasma membrane, e.g. a cilium, lamellipodium, or axon. http://identifiers.org/ncbigene/18504 Pax2 (Mmus) http://identifiers.org/ncbigene/18545 Pcp2 (Mmus) http://purl.obolibrary.org/obo/GO_0098693 regulation of synaptic vesicle cycle http://purl.obolibrary.org/obo/GO_0060627 regulation of vesicle-mediated transport Any process that modulates the frequency, rate or extent of the synaptic vesicle cycle. http://identifiers.org/ncbigene/18553 Pcsk6 (Mmus) http://purl.obolibrary.org/obo/PATO_0045026 normal life span http://purl.obolibrary.org/obo/PATO_0045001 normal object quality A life span which is relatively normal or average. http://identifiers.org/ncbigene/18588 Pde6g (Mmus) http://purl.obolibrary.org/obo/GO_0062012 regulation of small molecule metabolic process http://purl.obolibrary.org/obo/GO_0019222 regulation of metabolic process Any process that modulates the rate, frequency or extent of a small molecule metabolic process. http://identifiers.org/ncbigene/18595 Pdgfra (Mmus) http://purl.obolibrary.org/obo/GO_0110116 regulation of compound eye photoreceptor cell differentiation http://purl.obolibrary.org/obo/GO_0046532 regulation of photoreceptor cell differentiation Any process that modulates the frequency, rate or extent of compound eye photoreceptor cell differentiation. http://identifiers.org/ncbigene/18610 Pdyn (Mmus) http://identifiers.org/ncbigene/19049 Ppp1r1b (Mmus) http://purl.obolibrary.org/obo/GO_0110117 positive regulation of compound eye photoreceptor cell differentiation http://purl.obolibrary.org/obo/GO_0046534 positive regulation of photoreceptor cell differentiation Any process that activates or increases the frequency, rate or extent of compound eye photoreceptor cell differentiation. http://identifiers.org/ncbigene/19051 Ppp1r17 (Mmus) http://identifiers.org/ncbigene/19216 Ptger1 (Mmus) http://identifiers.org/ncbigene/19227 Pthlh (Mmus) http://purl.obolibrary.org/obo/GO_0110118 negative regulation of compound eye photoreceptor cell differentiation http://purl.obolibrary.org/obo/GO_0046533 negative regulation of photoreceptor cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of compound eye photoreceptor cell differentiation. http://identifiers.org/ncbigene/19263 Ptprb (Mmus) http://identifiers.org/ncbigene/19293 Pvalb (Mmus) http://purl.obolibrary.org/obo/GO_0120180 cell-substrate junction disassembly http://purl.obolibrary.org/obo/GO_0150115 cell-substrate junction organization The disaggregation of a cell-substrate junction into its constituent components. http://identifiers.org/ncbigene/19734 Rgs16 (Mmus) http://identifiers.org/ncbigene/20200 S100a6 (Mmus) http://purl.obolibrary.org/obo/GO_0120187 positive regulation of protein localization to chromatin http://purl.obolibrary.org/obo/GO_1905634 regulation of protein localization to chromatin Any process that activates or increases the frequency, rate or extent of protein localization to chromatin. http://identifiers.org/ncbigene/20284 Scrg1 (Mmus) http://identifiers.org/ncbigene/20311 Cxcl5 (Mmus) http://purl.obolibrary.org/obo/GO_0120188 regulation of bile acid secretion http://purl.obolibrary.org/obo/GO_0032890 regulation of organic acid transport Any process that modulates the frequency, rate or extent of the controlled release of bile acid from a cell or a tissue. http://identifiers.org/ncbigene/20315 Cxcl12 (Mmus) http://identifiers.org/ncbigene/20363 Selenop (Mmus) http://purl.obolibrary.org/obo/GO_0120189 positive regulation of bile acid secretion http://purl.obolibrary.org/obo/GO_0032892 positive regulation of organic acid transport Any process that activates or increases the frequency, rate or extent of the controlled release of bile acid from a cell or a tissue. http://identifiers.org/ncbigene/20377 Sfrp1 (Mmus) http://identifiers.org/ncbigene/20378 Frzb (Mmus) http://purl.obolibrary.org/obo/GO_0120190 negative regulation of bile acid secretion http://purl.obolibrary.org/obo/GO_0032891 negative regulation of organic acid transport Any process that stops, prevents or reduces the frequency, rate or extent of the controlled release of bile acid from a cell or a tissue. http://identifiers.org/ncbigene/20440 St6gal1 (Mmus) http://identifiers.org/ncbigene/20491 Sla (Mmus) http://purl.obolibrary.org/obo/GO_0140236 translation at presynapse http://purl.obolibrary.org/obo/GO_0140241 translation at synapse Translation that occurs at the presynapse. http://identifiers.org/ncbigene/20743 Sptbn2 (Mmus) http://identifiers.org/ncbigene/208613 Tmem212 (Mmus) http://purl.obolibrary.org/obo/GO_0140237 translation at presynapse, modulating chemical synaptic transmission http://purl.obolibrary.org/obo/GO_0140236 translation at presynapse Translation that occurs at the presynapse, and that modulates chemical synaptic transmission. http://identifiers.org/ncbigene/208936 Adamts18 (Mmus) http://purl.obolibrary.org/obo/GO_0140239 postsynaptic endocytosis http://purl.obolibrary.org/obo/GO_0099003 vesicle-mediated transport in synapse A vesicle-mediated transport process in which the postsynapse take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle. http://identifiers.org/ncbigene/213435 Mylk3 (Mmus) http://purl.obolibrary.org/obo/GO_0140241 translation at synapse http://purl.obolibrary.org/obo/GO_0006412 translation Translation that occurs at the synapse. http://identifiers.org/ncbigene/213783 Plekhg1 (Mmus) http://identifiers.org/ncbigene/21386 Tbx3 (Mmus) http://purl.obolibrary.org/obo/GO_0140242 translation at postsynapse http://purl.obolibrary.org/obo/GO_0140241 translation at synapse Translation that occurs at the postsynapse. http://identifiers.org/ncbigene/21416 Tcf7l2 (Mmus) http://purl.obolibrary.org/obo/GO_0140243 regulation of translation at synapse http://purl.obolibrary.org/obo/GO_0006417 regulation of translation Any process that regulates translation occurring at the synapse. http://identifiers.org/ncbigene/21418 Tfap2a (Mmus) http://identifiers.org/ncbigene/21419 Tfap2b (Mmus) http://purl.obolibrary.org/obo/GO_0140245 regulation of translation at postsynapse http://purl.obolibrary.org/obo/GO_0140243 regulation of translation at synapse Any process that regulates translation occurring at the postsynapse. http://identifiers.org/ncbigene/215378 Brinp3 (Mmus) http://purl.obolibrary.org/obo/GO_0140246 protein catabolic process at synapse http://purl.obolibrary.org/obo/GO_0030163 protein catabolic process The chemical reactions and pathways resulting in the breakdown of a protein at a synapse. http://identifiers.org/ncbigene/216227 Slc17a8 (Mmus) http://purl.obolibrary.org/obo/GO_0140247 protein catabolic process at presynapse http://purl.obolibrary.org/obo/GO_0140246 protein catabolic process at synapse The chemical reactions and pathways resulting in the breakdown of a protein at a presynapse. http://identifiers.org/ncbigene/216616 Efemp1 (Mmus) http://identifiers.org/ncbigene/218194 Phactr1 (Mmus) http://purl.obolibrary.org/obo/GO_0140249 protein catabolic process at postsynapse http://purl.obolibrary.org/obo/GO_0140246 protein catabolic process at synapse The chemical reactions and pathways resulting in the breakdown of a protein at a postsynapse. http://identifiers.org/ncbigene/21824 Thbd (Mmus) http://identifiers.org/ncbigene/21828 Thbs4 (Mmus) http://purl.obolibrary.org/obo/GO_0140250 regulation protein catabolic process at synapse http://purl.obolibrary.org/obo/GO_0009894 regulation of catabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein at the synapse. http://identifiers.org/ncbigene/218772 Rarb (Mmus) http://purl.obolibrary.org/obo/GO_0140251 regulation protein catabolic process at presynapse http://purl.obolibrary.org/obo/GO_0140250 regulation protein catabolic process at synapse Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein at the presynapse. http://identifiers.org/ncbigene/21973 Top2a (Mmus) http://identifiers.org/ncbigene/21990 Tph1 (Mmus) http://purl.obolibrary.org/obo/GO_0140252 regulation protein catabolic process at postsynapse http://purl.obolibrary.org/obo/GO_0140250 regulation protein catabolic process at synapse Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein at the postsynapse. http://identifiers.org/ncbigene/22139 Ttr (Mmus) http://purl.obolibrary.org/obo/GO_0140271 hexose import across plasma membrane http://purl.obolibrary.org/obo/GO_0008645 hexose transmembrane transport The directed movement of hexose from outside of a cell, across the plasma membrane and into the cytosol. http://identifiers.org/ncbigene/22283 Ush2a (Mmus) http://identifiers.org/ncbigene/223332 Ranbp3l (Mmus) http://purl.obolibrary.org/obo/UBERON_0036304 anatomical border http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure An anatomical structure that is located along the line dividing two regions of an anatomical structure. http://identifiers.org/ncbigene/22348 Slc32a1 (Mmus) http://purl.obolibrary.org/obo/GO_0120261 regulation of heterochromatin organization http://purl.obolibrary.org/obo/GO_1902275 regulation of chromatin organization Any process that modulates the frequency, rate, extent or location of heterochromatin organization. http://identifiers.org/ncbigene/223843 Dbx2 (Mmus) http://identifiers.org/ncbigene/223970 Rmi2 (Mmus) http://purl.obolibrary.org/obo/GO_0120262 negative regulation of heterochromatin organization http://purl.obolibrary.org/obo/GO_1905268 negative regulation of chromatin organization Any process that stops, prevents, or reduces the frequency, rate or extent of heterochromatin organization. http://identifiers.org/ncbigene/224079 Atp13a4 (Mmus) http://purl.obolibrary.org/obo/GO_0120263 positive regulation of heterochromatin organization http://purl.obolibrary.org/obo/GO_1905269 positive regulation of chromatin organization Any process that activates or increases the frequency, rate or extent of heterochromatin organization. http://identifiers.org/ncbigene/226115 Opalin (Mmus) http://identifiers.org/ncbigene/226250 Afap1l2 (Mmus) http://purl.obolibrary.org/obo/GO_0120275 cerebral blood circulation http://purl.obolibrary.org/obo/GO_0008015 blood circulation The flow of blood through the network of arteries and veins supplying the cerebrum, enabling the transport of nutrients to the tissues and the removal of waste products. http://identifiers.org/ncbigene/227580 C1ql3 (Mmus) http://identifiers.org/ncbigene/22771 Zic1 (Mmus) http://purl.obolibrary.org/obo/GO_0120276 regulation of cerebral blood circulation http://purl.obolibrary.org/obo/GO_1903522 regulation of blood circulation Any process that modulates the frequency, rate or extent of cerebral blood circulation. http://identifiers.org/ncbigene/228731 Nkx2-4 (Mmus) http://purl.obolibrary.org/obo/GO_0120277 positive regulation of cerebral blood circulation http://purl.obolibrary.org/obo/GO_0120276 regulation of cerebral blood circulation Any process that activates or increases the frequency, rate or extent of cerebral blood circulation. http://identifiers.org/ncbigene/230726 Rhbdl2 (Mmus) http://identifiers.org/ncbigene/232174 Cyp26b1 (Mmus) http://purl.obolibrary.org/obo/GO_0120278 negative regulation of cerebral blood circulation http://purl.obolibrary.org/obo/GO_0120276 regulation of cerebral blood circulation Any process that stops, prevents or reduces the frequency, rate or extent of cerebral blood circulation. http://identifiers.org/ncbigene/232685 Lncpint (Mmus) http://purl.obolibrary.org/obo/CL_4023010 alpha7 GABAergic cortical interneuron (Mmus) http://purl.obolibrary.org/obo/CL_0010011 cerebral cortex GABAergic interneuron A GABAergic cortical interneuron that is strongly labelled for α7 nAChRs. These cells have soma found in L1 and have multipolar dendrites with vertically descending axonal collaterals that project deep into the column, usually branching and terminating in L5A. http://identifiers.org/ncbigene/233537 Gdpd4 (Mmus) http://identifiers.org/ncbigene/234258 Neil3 (Mmus) http://purl.obolibrary.org/obo/CL_4023011 lamp5 GABAergic interneuron http://purl.obolibrary.org/obo/CL_4023064 caudal ganglionic eminence derived interneuron A transcriptomically distinct GABAergic neuron located in the cerebral cortex that expresses Lamp5. http://identifiers.org/ncbigene/235130 Adamts15 (Mmus) http://identifiers.org/ncbigene/237979 Sdk2 (Mmus) http://purl.obolibrary.org/obo/CL_4023015 sncg GABAergic interneuron http://purl.obolibrary.org/obo/CL_4023064 caudal ganglionic eminence derived interneuron A transcriptomically distinct GABAergic neuron located in the cerebral cortex that expresses Gamma-synuclein. http://identifiers.org/ncbigene/23829 C1ql1 (Mmus) http://purl.obolibrary.org/obo/CL_4023016 VIP GABAergic interneuron http://purl.obolibrary.org/obo/CL_4023064 caudal ganglionic eminence derived interneuron A transcriptomically distinct GABAergic neuron derived from the CGE and that expresses the vasoactive intestinal polypeptide. Its soma is located in the forebrain. http://identifiers.org/ncbigene/23876 Fbln5 (Mmus) http://purl.obolibrary.org/obo/CL_4023017 sst GABAergic interneuron http://purl.obolibrary.org/obo/CL_4023069 medial ganglionic eminence derived GABAergic interneuron A transcriptomically distinct GABAergic neuron located in the cerebral cortex that expresses somatostatin (sst) and derived from the MGE. http://identifiers.org/ncbigene/239337 Adamts12 (Mmus) http://identifiers.org/ncbigene/239405 Rspo2 (Mmus) http://purl.obolibrary.org/obo/CL_4023018 pvalb GABAergic interneuron http://purl.obolibrary.org/obo/CL_4023063 medial ganglionic eminence derived interneuron A transcriptomically distinct GABAergic interneuron with a soma located in the pallium. These neurons express Parvalbumin. http://identifiers.org/ncbigene/240479 Dipk1c (Mmus) http://identifiers.org/ncbigene/241489 Pde11a (Mmus) http://purl.obolibrary.org/obo/GO_0140572 vacuole fission http://purl.obolibrary.org/obo/GO_0048285 organelle fission The division of a vacuole within a cell to form two or more separate vacuoles. http://identifiers.org/ncbigene/242253 Wdr63 (Mmus) http://purl.obolibrary.org/obo/PATO_0070021 inverted pyramidal morphology http://purl.obolibrary.org/obo/PATO_0070017 standard pyramidal morphology A pyramidal cell morphology that inheres in neurons which have an apical tree which is oriented towards the white matter. http://identifiers.org/ncbigene/242425 Gabbr2 (Mmus) http://identifiers.org/ncbigene/242735 Lrrc38 (Mmus) http://purl.obolibrary.org/obo/UBERON_8440005 rostral periventricular region of the third ventricle http://purl.obolibrary.org/obo/UBERON_0035014 functional part of brain A functional anatomical construct containing the key estrogen-regulated inputs to gonadotropin-releasing hormone expressing (GnRH) neurons necessary for estrogen positive feedback. The rostral periventricular region of the third ventricle contains a population of neurons, scattered through the nuclei of the anteroventral periventricular (AVPV), periventricular preoptic (PVpo), and median preoptic (MEPO), that project directly to GnRH neurons and express ER-alpha. http://identifiers.org/ncbigene/243369 Sspo (Mmus) http://identifiers.org/ncbigene/243937 Zfp536 (Mmus) http://purl.obolibrary.org/obo/UBERON_0039377 urethral vein http://purl.obolibrary.org/obo/UBERON_0001638 vein A vein that drains the urethra. http://identifiers.org/ncbigene/244954 Prss35 (Mmus) http://identifiers.org/ncbigene/245827 Fat2 (Mmus) http://purl.obolibrary.org/obo/UBERON_8410068 capillary of small intestine http://purl.obolibrary.org/obo/UBERON_0001982 capillary A capillary that is part of a small intestine. http://identifiers.org/ncbigene/246049 Slc36a2 (Mmus) http://identifiers.org/ncbigene/26558 Homer3 (Mmus) http://purl.obolibrary.org/obo/CL_4030015 kidney collecting duct alpha-intercalated cell http://purl.obolibrary.org/obo/CL_1001432 kidney collecting duct intercalated cell A renal alpha-intercalated cell that is part of the collecting duct of the renal tubule. http://identifiers.org/ncbigene/26563 Ror1 (Mmus) http://purl.obolibrary.org/obo/CL_4023181 hypendymal cell http://purl.obolibrary.org/obo/CL_0002319 neural cell A neurecto-epithelial cell that is part of the basal layer of the subcommissural organ and specializes in the secretion of proteins into the subarachnoid space. Hypendymal cells have similar characteristics to ependymal cells and express SCO-spondin. http://identifiers.org/ncbigene/268527 Greb1 (Mmus) http://identifiers.org/ncbigene/268709 Fam107a (Mmus) http://purl.obolibrary.org/obo/CL_4030005 kidney collecting duct beta-intercalated cell http://purl.obolibrary.org/obo/CL_1000715 kidney cortex collecting duct intercalated cell A renal beta-intercalated cell that is part of the cortical collecting duct. The medullary collecting duct does not contain the renal beta-intercalated cell type. http://identifiers.org/ncbigene/268816 Mroh5 (Mmus) http://identifiers.org/ncbigene/269019 Stk32a (Mmus) http://purl.obolibrary.org/obo/CL_0017011 hillock cell of prostatic urethral epithelium http://purl.obolibrary.org/obo/CL_0017010 hillock cell of urethral epithelium A hillock cell that is part of the prostatic urethra. http://identifiers.org/ncbigene/269275 Acvr1c (Mmus) http://identifiers.org/ncbigene/269629 Lhfpl3 (Mmus) http://purl.obolibrary.org/obo/CL_0017010 hillock cell of urethral epithelium http://purl.obolibrary.org/obo/CL_1000296 epithelial cell of urethra A hillock cell that is part of the urethra. http://identifiers.org/ncbigene/26968 Islr (Mmus) http://purl.obolibrary.org/obo/CL_0004215 type 5a cone bipolar cell http://purl.obolibrary.org/obo/CL_0000757 type 5 cone bipolar cell (sensu Mus) A type 5 cone bipolar cell with narrowly stratified post synaptic terminals. http://identifiers.org/ncbigene/270150 Ccdc153 (Mmus) http://identifiers.org/ncbigene/27428 Shroom3 (Mmus) http://purl.obolibrary.org/obo/CL_4023068 thalamic excitatory neuron http://purl.obolibrary.org/obo/CL_0012001 neuron of the forebrain An excitatory neuron that has its soma located in the thalamic complex. This neuron type can be involved in a series of circuits related to sensory integration, motor integration, pain processing, social behaviour and reward response. http://identifiers.org/ncbigene/276952 Rasl10b (Mmus) http://identifiers.org/ncbigene/277468 Slc39a12 (Mmus) http://purl.obolibrary.org/obo/CL_4030039 von Economo neuron http://purl.obolibrary.org/obo/CL_4023009 extratelencephalic-projecting glutamatergic cortical neuron An extratelencephalic-projecting glutamatergic cortical neuron that is morphologically-defined with a large, spindle-shaped cell body, thick bipolar dendrites with limited branching and a moderate density of spines, and often an axon initial segment that emanates from the side of the cell body. This cell type is associated with markers POU3F, BMP3 and ITGA4. http://identifiers.org/ncbigene/278304 Zfp385c (Mmus) http://identifiers.org/ncbigene/30952 Cngb3 (Mmus) http://purl.obolibrary.org/obo/CL_4030043 matrix D1 medium spiny neuron http://purl.obolibrary.org/obo/CL_4023026 direct pathway medium spiny neuron A DRD1-expressing medium spiny neuron that is part of a matrix compartment of dorsal striatum. http://identifiers.org/ncbigene/319922 Vwc2 (Mmus) http://purl.obolibrary.org/obo/CL_4030047 matrix D2 medium spiny neuron http://purl.obolibrary.org/obo/CL_0002613 striatum neuron A DRD2-expressing medium spiny neuron that is part of a matrix compartment of dorsal striatum. http://identifiers.org/ncbigene/319951 A230001M10Rik (Mmus) http://purl.obolibrary.org/obo/CL_4030048 striosomal D1 medium spiny neuron http://purl.obolibrary.org/obo/CL_4023026 direct pathway medium spiny neuron A DRD1-expressing medium spiny neuron that is part of a striosome of dorsal striatum. http://identifiers.org/ncbigene/319984 Jph4 (Mmus) http://purl.obolibrary.org/obo/CL_4030049 striosomal D2 medium spiny neuron http://purl.obolibrary.org/obo/CL_0002613 striatum neuron A DRD2-expressing medium spiny neuron that is part of a striosome of dorsal striatum. http://identifiers.org/ncbigene/320772 Mdga2 (Mmus) http://purl.obolibrary.org/obo/CL_4030050 D1/D2-hybrid medium spiny neuron http://purl.obolibrary.org/obo/CL_1001474 medium spiny neuron A medium spiny neuron that expresses both DRD1 and DRD2 and is part of an extra-striosomal part of dorsal striatum. http://identifiers.org/ncbigene/320784 C230072F16Rik (Mmus) http://identifiers.org/ncbigene/320981 Enpp6 (Mmus) http://purl.obolibrary.org/obo/CL_4030051 nucleus accumbens shell and olfactory tubercle D1 medium spiny neuron http://purl.obolibrary.org/obo/CL_1001474 medium spiny neuron A DRD1-expressing medium spiny neuron that is part of a nucleus accumbens shell or olfactory tubercle. http://identifiers.org/ncbigene/328354 Gm5087 (Mmus) http://identifiers.org/ncbigene/329078 Emx2os (Mmus) http://purl.obolibrary.org/obo/CL_4030052 nucleus accumbens shell and olfactory tubercle D2 medium spiny neuron http://purl.obolibrary.org/obo/CL_1001474 medium spiny neuron A DRD2-expressing medium spiny neuron that is part of a nucleus accumbens shell or olfactory tubercle. http://identifiers.org/ncbigene/329274 Fam163a (Mmus) http://identifiers.org/ncbigene/338521 Fa2h (Mmus) http://purl.obolibrary.org/obo/CL_4030053 Islands of Calleja granule cell http://purl.obolibrary.org/obo/CL_0002613 striatum neuron A GABAergic neuron that resides in the islands of calleja and shows the cytoarchitectural and molecular features characteristic of this granule-like cell population. In mice and primates, it expresses D1 and D3 dopamine receptors (Drd1; Drd3), GABAergic markers (GAD1/2) and form densely packed granule cell clusters in the olfactory tubercle within the ventral striatum. Moreover it receives dense dopaminergic input from the VTA, and functionally associated with self-grooming behaviors and depression-like behaviors. http://identifiers.org/ncbigene/373864 Col27a1 (Mmus) http://identifiers.org/ncbigene/381112 Arhgef33 (Mmus) http://purl.obolibrary.org/obo/CL_4030054 D1-NUDAP medium spiny neuron http://purl.obolibrary.org/obo/CL_1001474 medium spiny neuron A DRD1-expressing medium spiny neuron that is part of dense, RXFP1-positive cell islands throughout the nucleus accumbens, putamen, and near the adjacent septal nuclei. http://identifiers.org/ncbigene/384071 Slc25a34 (Mmus) http://identifiers.org/ncbigene/407831 Tmem204 (Mmus) http://purl.obolibrary.org/obo/CL_4030055 intermediate cell of urothelium http://purl.obolibrary.org/obo/CL_0000731 urothelial cell A urothelial cell that is part of the regenerative layer(s) of cells directly superficial to basal cells in urothelium. The layer of intermediate cells in the urothelium ranges from one to several layers thick depending on the species with intermediate cells attached to adjacent cell layers and one another via desmosomes. http://identifiers.org/ncbigene/433022 Plcxd2 (Mmus) http://identifiers.org/ncbigene/50768 Dlc1 (Mmus) http://purl.obolibrary.org/obo/CL_4030056 umbrella cell of urothelium http://purl.obolibrary.org/obo/CL_0000731 urothelial cell A urothelial cell that is terminally differentiated and part of the urothelial apical surface that forms the high-resistance barrier of urothelium. Umbrella cells have been described as the largest of urothelial cell types, highly polarized, and, in some species, multinucleated. In the relaxed state, these cells form a dome-shaped structure at the apical pole and can also cover multiple underlying intermediate cells, leading to the name umbrella cells. In contrast, these cells flatten when the bladder is filled. http://identifiers.org/ncbigene/50779 Rgs6 (Mmus) http://identifiers.org/ncbigene/50914 Olig1 (Mmus) http://purl.obolibrary.org/obo/CL_4040003 fetal pre-type II pulmonary alveolar epithelial cell http://purl.obolibrary.org/obo/CL_0000322 pulmonary alveolar epithelial cell Precursor of type II pneumocyte. These cells do not have lamellar bodies, which are a marker of type II pneumocyte maturity. http://identifiers.org/ncbigene/50929 Il22 (Mmus) http://identifiers.org/ncbigene/53896 Slc7a10 (Mmus) http://purl.obolibrary.org/obo/UBERON_8480068 saphenous vein smooth muscle tissue http://purl.obolibrary.org/obo/UBERON_0004696 venous system smooth muscle A portion of smooth muscle tissue that is part of a saphenous vein. http://identifiers.org/ncbigene/54216 Pcdh7 (Mmus) http://identifiers.org/ncbigene/54612 Sfrp5 (Mmus) http://purl.obolibrary.org/obo/UBERON_8480074 skin of gonad http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure A zone of skin part of some gonad. http://identifiers.org/ncbigene/56213 Htra1 (Mmus) http://identifiers.org/ncbigene/56410 Cbln3 (Mmus) http://purl.obolibrary.org/obo/GO_0160093 chordate pharynx development http://purl.obolibrary.org/obo/GO_0060465 pharynx development The process whose specific outcome is the progression of cordate pharynx over time, from its formation to the mature structure. http://identifiers.org/ncbigene/56744 Pf4 (Mmus) http://identifiers.org/ncbigene/56747 Sez6l (Mmus) http://purl.obolibrary.org/obo/UBERON_8600021 chorionic plate blood vessel http://purl.obolibrary.org/obo/UBERON_0022358 placenta blood vessel A blood vessel that is part of the chorionic plate. http://identifiers.org/ncbigene/57265 Fzd2 (Mmus) http://purl.obolibrary.org/obo/CL_4033065 preplasmablast http://purl.obolibrary.org/obo/CL_0000785 mature B cell A mature B cell that serves as an intermediate stage in the differentiation of naive B cells into a plasmablast. A preplasmablast expresses CD30 and IL-6R and lacks expression of CD20, CD23, CD38 and CD138. http://identifiers.org/ncbigene/574402 Gpr17 (Mmus) http://identifiers.org/ncbigene/57915 Tbc1d1 (Mmus) http://purl.obolibrary.org/obo/CL_4042007 protoplasmic astrocyte http://purl.obolibrary.org/obo/CL_0002605 astrocyte of the cerebral cortex An astrocyte with highly branched protrusions, found in neocortex layers 2-6. It is involved with the formation and elimination of synapses, glutamate clearance, modulation of synaptic functions and regulation of blood flow in response to synaptic activity. http://identifiers.org/ncbigene/58807 Slco1c1 (Mmus) http://identifiers.org/ncbigene/59058 Bhlhe22 (Mmus) http://purl.obolibrary.org/obo/CL_4042008 fibrous astrocyte http://purl.obolibrary.org/obo/CL_0000127 astrocyte A cell type located in the first layer of the neocortex with radial protrusions extending transversely into the deeper cortex layers, herby facilitating communication across neurons, astrocytes, capillaries, meninges and cerebrospinal fluid through contact with neurons, pia mater and capillaries. http://identifiers.org/ncbigene/620376 Gm6145 (Mmus) http://identifiers.org/ncbigene/624549 Gm29683 (Mmus) http://purl.obolibrary.org/obo/CL_4042009 interlaminar astrocyte http://purl.obolibrary.org/obo/CL_0002605 astrocyte of the cerebral cortex An astrocyte type that presents radial protrusions across the layers of a cortex. The soma of this astrocyte is part of the first layer of a neocortex. This astrocyte extents its protrusions transversally to the deeper layers of a cortex and it creates contact with neurons, the pia matter and capillaries. This astrocyte is involved in facilitating the communication across neurons, astrocytes, capillaries, meninges and the cerebrospinal fluid. http://identifiers.org/ncbigene/626082 Gm20754 (Mmus) http://identifiers.org/ncbigene/629147 Ctxn3 (Mmus) http://purl.obolibrary.org/obo/CL_4042010 pial interlaminar astrocyte http://purl.obolibrary.org/obo/CL_4042009 interlaminar astrocyte An interlaminar astrocyte whose soma is part of the first layer of a neocortex and is in contact with a pia surface. http://identifiers.org/ncbigene/63830 Kcnq1ot1 (Mmus) http://identifiers.org/ncbigene/64085 Clstn2 (Mmus) http://purl.obolibrary.org/obo/CL_4042011 subpial interlaminar astrocyte http://purl.obolibrary.org/obo/CL_4042009 interlaminar astrocyte An interlaminar astrocyte type whose soma is part of the upper first layer of the neocortex and its processes extend to a pia surface. http://identifiers.org/ncbigene/65969 Cubn (Mmus) http://identifiers.org/ncbigene/66214 Rgcc (Mmus) http://purl.obolibrary.org/obo/STATO_0000663 F-beta score http://purl.obolibrary.org/obo/STATO_0000623 measure of agreement The F-beta score is a measure of a model's accuracy, specifically designed to evaluate the performance of binary classification models. It is a generalized form of the F1 score, which itself is the harmonic mean of precision and recall. The F-beta score introduces a way to weigh recall more heavily than precision (or vice versa) depending on the value of beta. http://identifiers.org/ncbigene/66270 Retreg1 (Mmus) http://identifiers.org/ncbigene/66402 Sln (Mmus) http://purl.obolibrary.org/obo/GO_0160212 glycine-gated cation channel activity http://purl.obolibrary.org/obo/GO_0099094 ligand-gated monoatomic cation channel activity Enables the transmembrane transfer of a cation by a channel that opens when glycine is bound by the channel complex or one of its constituent parts on the extracellular side of the plasma membrane. http://identifiers.org/ncbigene/66425 Pcp4l1 (Mmus) http://identifiers.org/ncbigene/665119 Sec14l5 (Mmus) http://purl.obolibrary.org/obo/GO_0120544 polypeptide conformation or assembly isomerase activity http://purl.obolibrary.org/obo/GO_0120543 macromolecular conformation isomerase activity Catalysis of a reaction that alters the conformation or assembly of a polypeptide. http://identifiers.org/ncbigene/66540 Fam107b (Mmus) http://identifiers.org/ncbigene/66673 Sorcs3 (Mmus) http://purl.obolibrary.org/obo/NCBITaxon_6681 Malacostraca http://purl.obolibrary.org/obo/NCBITaxon_2172821 Multicrustacea http://identifiers.org/ncbigene/667742 Piezo2 (Mmus) http://identifiers.org/ncbigene/66905 Plin3 (Mmus) http://purl.obolibrary.org/obo/UBERON_0005613 left dorsal aorta http://purl.obolibrary.org/obo/UBERON_0003513 trunk blood vessel http://identifiers.org/ncbigene/66977 Nuf2 (Mmus) http://identifiers.org/ncbigene/67473 Slc47a1 (Mmus) http://purl.obolibrary.org/obo/UBERON_0005622 right dorsal aorta http://purl.obolibrary.org/obo/UBERON_0003513 trunk blood vessel http://identifiers.org/ncbigene/67801 Pllp (Mmus) http://identifiers.org/ncbigene/67844 Rab32 (Mmus) http://purl.obolibrary.org/obo/NCBITaxon_451864 Dikarya http://purl.obolibrary.org/obo/NCBITaxon_4751 Fungi http://identifiers.org/ncbigene/68026 Pclaf (Mmus) http://identifiers.org/ncbigene/68070 Pdzd2 (Mmus) http://purl.obolibrary.org/obo/NCBITaxon_451866 Taphrinomycotina http://purl.obolibrary.org/obo/NCBITaxon_4890 Ascomycota http://identifiers.org/ncbigene/68178 Cgnl1 (Mmus) http://purl.obolibrary.org/obo/UBERON_0000005 chemosensory organ http://purl.obolibrary.org/obo/UBERON_0000020 sense organ http://identifiers.org/ncbigene/68458 Ppp1r14a (Mmus) http://purl.obolibrary.org/obo/UBERON_0005282 ventricular system of brain http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system http://identifiers.org/ncbigene/68743 Anln (Mmus) http://purl.obolibrary.org/obo/UBERON_0005726 chemosensory system http://purl.obolibrary.org/obo/UBERON_0001032 sensory system http://identifiers.org/ncbigene/70134 2210011C24Rik (Mmus) http://purl.obolibrary.org/obo/UBERON_0007037 mechanosensory system http://purl.obolibrary.org/obo/UBERON_0001032 sensory system http://identifiers.org/ncbigene/71481 Alpk1 (Mmus) http://identifiers.org/ncbigene/71660 Rarres2 (Mmus) http://purl.obolibrary.org/obo/UBERON_0008713 pectoral girdle and thoracic body wall skeletal muscle http://purl.obolibrary.org/obo/UBERON_0001134 skeletal muscle tissue http://identifiers.org/ncbigene/72258 Kcnk10 (Mmus) http://purl.obolibrary.org/obo/UBERON_0009657 artery of lip http://purl.obolibrary.org/obo/UBERON_0001637 artery http://identifiers.org/ncbigene/72446 Prr5l (Mmus) http://purl.obolibrary.org/obo/UBERON_0011693 extraembryonic portion of umbilical artery http://purl.obolibrary.org/obo/UBERON_0000478 extraembryonic structure http://identifiers.org/ncbigene/72555 Shisa9 (Mmus) http://purl.obolibrary.org/obo/UBERON_0039355 urethral artery http://purl.obolibrary.org/obo/UBERON_0001637 artery http://identifiers.org/ncbigene/72902 Spock3 (Mmus) http://purl.obolibrary.org/obo/UBERON_0005604 extrahepatic part of hepatic duct http://purl.obolibrary.org/obo/UBERON_0002394 bile duct http://identifiers.org/ncbigene/72927 Hepacam (Mmus) http://identifiers.org/ncbigene/72961 Slc17a7 (Mmus) http://purl.obolibrary.org/obo/UBERON_0010394 lymphocyte domain http://purl.obolibrary.org/obo/UBERON_0010001 cell cluster organ http://identifiers.org/ncbigene/73940 Hapln2 (Mmus) http://purl.obolibrary.org/obo/NCBITaxon_131567 cellular organisms http://purl.obolibrary.org/obo/NCBITaxon_1 root http://identifiers.org/ncbigene/74145 F13a1 (Mmus) http://purl.obolibrary.org/obo/NCBITaxon_39107 Murinae http://purl.obolibrary.org/obo/NCBITaxon_10066 Muridae http://identifiers.org/ncbigene/74318 Hopx (Mmus) http://purl.obolibrary.org/obo/NCBITaxon_862507 Mus http://purl.obolibrary.org/obo/NCBITaxon_10088 Mus http://identifiers.org/ncbigene/74563 Rasgef1c (Mmus) http://purl.obolibrary.org/obo/NCBITaxon_117571 Euteleostomi http://purl.obolibrary.org/obo/NCBITaxon_117570 Teleostomi http://identifiers.org/ncbigene/75396 Spp2 (Mmus) http://purl.obolibrary.org/obo/NCBITaxon_7898 Actinopterygii http://purl.obolibrary.org/obo/NCBITaxon_117571 Euteleostomi http://identifiers.org/ncbigene/75465 Dynlrb2 (Mmus) http://identifiers.org/ncbigene/76422 Mroh3 (Mmus) http://purl.obolibrary.org/obo/NCBITaxon_8287 Sarcopterygii http://purl.obolibrary.org/obo/NCBITaxon_117571 Euteleostomi http://identifiers.org/ncbigene/76453 Prss23 (Mmus) http://purl.obolibrary.org/obo/NCBITaxon_6231 Nematoda http://purl.obolibrary.org/obo/NCBITaxon_1206794 Ecdysozoa http://identifiers.org/ncbigene/77018 Col25a1 (Mmus) http://purl.obolibrary.org/obo/NCBITaxon_88770 Panarthropoda http://purl.obolibrary.org/obo/NCBITaxon_1206794 Ecdysozoa http://identifiers.org/ncbigene/77125 Il33 (Mmus) http://purl.obolibrary.org/obo/NCBITaxon_6157 Platyhelminthes http://purl.obolibrary.org/obo/NCBITaxon_1206795 Lophotrochozoa http://identifiers.org/ncbigene/77808 Gm44196 (Mmus) http://purl.obolibrary.org/obo/NCBITaxon_2759 Eukaryota http://purl.obolibrary.org/obo/NCBITaxon_131567 cellular organisms http://identifiers.org/ncbigene/78748 Rassf10 (Mmus) http://identifiers.org/ncbigene/78754 Galnt15 (Mmus) http://purl.obolibrary.org/obo/NCBITaxon_8492 Archosauria http://purl.obolibrary.org/obo/NCBITaxon_1329799 Archelosauria http://identifiers.org/ncbigene/80837 Rhoj (Mmus) http://purl.obolibrary.org/obo/NCBITaxon_32523 Tetrapoda http://purl.obolibrary.org/obo/NCBITaxon_1338369 Dipnotetrapodomorpha http://identifiers.org/ncbigene/83430 Il23a (Mmus) http://purl.obolibrary.org/obo/NCBITaxon_314145 Laurasiatheria http://purl.obolibrary.org/obo/NCBITaxon_1437010 Boreoeutheria http://identifiers.org/ncbigene/83453 Chrdl1 (Mmus) http://purl.obolibrary.org/obo/NCBITaxon_314146 Euarchontoglires http://purl.obolibrary.org/obo/NCBITaxon_1437010 Boreoeutheria http://identifiers.org/ncbigene/83921 Cemip2 (Mmus) http://purl.obolibrary.org/obo/NCBITaxon_41665 Neopterygii http://purl.obolibrary.org/obo/NCBITaxon_186623 Actinopteri http://identifiers.org/ncbigene/96875 Prg4 (Mmus) http://identifiers.org/ncbigene/98267 Stk17b (Mmus) http://purl.obolibrary.org/obo/NCBITaxon_6657 Crustacea http://purl.obolibrary.org/obo/NCBITaxon_197562 Pancrustacea http://identifiers.org/ncbigene/98363 Efhd1 (Mmus) http://purl.obolibrary.org/obo/NCBITaxon_6960 Hexapoda http://purl.obolibrary.org/obo/NCBITaxon_197562 Pancrustacea https://purl.brain-bican.org/ontology/mbao/MBA_348 Midbrain, behavioral state related http://purl.obolibrary.org/obo/NCBITaxon_197562 Pancrustacea http://purl.obolibrary.org/obo/NCBITaxon_197563 Mandibulata https://purl.brain-bican.org/ontology/mbao/MBA_386 Medulla, sensory related http://purl.obolibrary.org/obo/NCBITaxon_33154 Opisthokonta http://purl.obolibrary.org/obo/NCBITaxon_2759 Eukaryota https://purl.brain-bican.org/ontology/mbao/MBA_960 cerebellum related fiber tracts http://purl.obolibrary.org/obo/NCBITaxon_314147 Glires http://purl.obolibrary.org/obo/NCBITaxon_314146 Euarchontoglires http://identifiers.org/ensembl/ENSG00000006128 TAC1 http://purl.obolibrary.org/obo/NCBITaxon_9989 Rodentia http://purl.obolibrary.org/obo/NCBITaxon_314147 Glires http://identifiers.org/ensembl/ENSG00000010327 STAB1 http://purl.obolibrary.org/obo/NCBITaxon_32524 Amniota http://purl.obolibrary.org/obo/NCBITaxon_32523 Tetrapoda http://identifiers.org/ensembl/ENSG00000038295 TLL1 http://identifiers.org/ensembl/ENSG00000038945 MSR1 http://purl.obolibrary.org/obo/NCBITaxon_40674 Mammalia http://purl.obolibrary.org/obo/NCBITaxon_32524 Amniota http://identifiers.org/ensembl/ENSG00000041982 TNC http://purl.obolibrary.org/obo/NCBITaxon_8457 Sauropsida http://purl.obolibrary.org/obo/NCBITaxon_32524 Amniota http://identifiers.org/ensembl/ENSG00000047648 ARHGAP6 http://purl.obolibrary.org/obo/NCBITaxon_9347 Eutheria http://purl.obolibrary.org/obo/NCBITaxon_32525 Theria http://identifiers.org/ensembl/ENSG00000047936 ROS1 http://identifiers.org/ensembl/ENSG00000050730 TNIP3 http://purl.obolibrary.org/obo/NCBITaxon_1329799 Archelosauria http://purl.obolibrary.org/obo/NCBITaxon_32561 Sauria http://identifiers.org/ensembl/ENSG00000051128 HOMER3 http://purl.obolibrary.org/obo/NCBITaxon_33208 Metazoa http://purl.obolibrary.org/obo/NCBITaxon_33154 Opisthokonta http://identifiers.org/ensembl/ENSG00000053747 LAMA3 http://purl.obolibrary.org/obo/NCBITaxon_28009 Choanoflagellata http://purl.obolibrary.org/obo/NCBITaxon_33154 Opisthokonta http://identifiers.org/ensembl/ENSG00000072694 FCGR2B http://purl.obolibrary.org/obo/NCBITaxon_6072 Eumetazoa http://purl.obolibrary.org/obo/NCBITaxon_33208 Metazoa http://identifiers.org/ensembl/ENSG00000078898 BPIFB2 http://purl.obolibrary.org/obo/NCBITaxon_33317 Protostomia http://purl.obolibrary.org/obo/NCBITaxon_33213 Bilateria http://identifiers.org/ensembl/ENSG00000079691 CARMIL1 http://purl.obolibrary.org/obo/NCBITaxon_33511 Deuterostomia http://purl.obolibrary.org/obo/NCBITaxon_33213 Bilateria http://identifiers.org/ensembl/ENSG00000082293 COL19A1 http://identifiers.org/ensembl/ENSG00000082482 KCNK2 http://purl.obolibrary.org/obo/NCBITaxon_1206794 Ecdysozoa http://purl.obolibrary.org/obo/NCBITaxon_33317 Protostomia http://identifiers.org/ensembl/ENSG00000082684 SEMA5B http://purl.obolibrary.org/obo/NCBITaxon_7711 Chordata http://purl.obolibrary.org/obo/NCBITaxon_33511 Deuterostomia http://identifiers.org/ensembl/ENSG00000100292 HMOX1 http://purl.obolibrary.org/obo/NCBITaxon_10066 Muridae http://purl.obolibrary.org/obo/NCBITaxon_337687 Muroidea http://identifiers.org/ensembl/ENSG00000100362 PVALB http://purl.obolibrary.org/obo/NCBITaxon_10088 Mus http://purl.obolibrary.org/obo/NCBITaxon_39107 Murinae http://identifiers.org/ensembl/ENSG00000100604 CHGA http://purl.obolibrary.org/obo/NCBITaxon_32525 Theria http://purl.obolibrary.org/obo/NCBITaxon_40674 Mammalia http://identifiers.org/ensembl/ENSG00000101134 DOK5 http://purl.obolibrary.org/obo/NCBITaxon_32443 Teleostei http://purl.obolibrary.org/obo/NCBITaxon_41665 Neopterygii http://identifiers.org/ensembl/ENSG00000107796 ACTA2 http://identifiers.org/ensembl/ENSG00000111215 PRR4 http://purl.obolibrary.org/obo/NCBITaxon_436489 Saurischia http://purl.obolibrary.org/obo/NCBITaxon_436486 Dinosauria http://identifiers.org/ensembl/ENSG00000113532 ST8SIA4 http://purl.obolibrary.org/obo/NCBITaxon_436491 Theropoda http://purl.obolibrary.org/obo/NCBITaxon_436489 Saurischia http://identifiers.org/ensembl/ENSG00000114805 PLCH1 http://purl.obolibrary.org/obo/NCBITaxon_436492 Coelurosauria http://purl.obolibrary.org/obo/NCBITaxon_436491 Theropoda http://identifiers.org/ensembl/ENSG00000115593 SMYD1 http://purl.obolibrary.org/obo/NCBITaxon_8782 Aves http://purl.obolibrary.org/obo/NCBITaxon_436492 Coelurosauria http://identifiers.org/ensembl/ENSG00000118513 MYB http://purl.obolibrary.org/obo/NCBITaxon_33213 Bilateria http://purl.obolibrary.org/obo/NCBITaxon_6072 Eumetazoa http://identifiers.org/ensembl/ENSG00000118523 CCN2 http://identifiers.org/ensembl/ENSG00000119547 ONECUT2 http://purl.obolibrary.org/obo/NCBITaxon_119089 Chromadorea http://purl.obolibrary.org/obo/NCBITaxon_6231 Nematoda http://identifiers.org/ensembl/ENSG00000122585 NPY http://purl.obolibrary.org/obo/NCBITaxon_197563 Mandibulata http://purl.obolibrary.org/obo/NCBITaxon_6656 Arthropoda http://identifiers.org/ensembl/ENSG00000122852 SFTPA1 http://purl.obolibrary.org/obo/NCBITaxon_72041 Eumalacostraca http://purl.obolibrary.org/obo/NCBITaxon_6681 Malacostraca http://identifiers.org/ensembl/ENSG00000124302 CHST8 http://purl.obolibrary.org/obo/NCBITaxon_6683 Decapoda http://purl.obolibrary.org/obo/NCBITaxon_6682 Eucarida http://identifiers.org/ensembl/ENSG00000124491 F13A1 http://purl.obolibrary.org/obo/NCBITaxon_6692 Pleocyemata http://purl.obolibrary.org/obo/NCBITaxon_6683 Decapoda http://identifiers.org/ensembl/ENSG00000125869 LAMP5 http://purl.obolibrary.org/obo/NCBITaxon_6752 Brachyura http://purl.obolibrary.org/obo/NCBITaxon_6692 Pleocyemata http://identifiers.org/ensembl/ENSG00000128536 CDHR3 http://identifiers.org/ensembl/ENSG00000131097 HIGD1B http://purl.obolibrary.org/obo/NCBITaxon_50557 Insecta http://purl.obolibrary.org/obo/NCBITaxon_6960 Hexapoda http://identifiers.org/ensembl/ENSG00000131471 AOC3 http://purl.obolibrary.org/obo/NCBITaxon_6682 Eucarida http://purl.obolibrary.org/obo/NCBITaxon_72041 Eumalacostraca http://identifiers.org/ensembl/ENSG00000131747 TOP2A http://purl.obolibrary.org/obo/NCBITaxon_89593 Craniata http://purl.obolibrary.org/obo/NCBITaxon_7711 Chordata http://identifiers.org/ensembl/ENSG00000134138 MEIS2 http://purl.obolibrary.org/obo/NCBITaxon_7776 Gnathostomata http://purl.obolibrary.org/obo/NCBITaxon_7742 Vertebrata http://identifiers.org/ensembl/ENSG00000134443 GRP http://purl.obolibrary.org/obo/NCBITaxon_117570 Teleostomi http://purl.obolibrary.org/obo/NCBITaxon_7776 Gnathostomata http://identifiers.org/ensembl/ENSG00000137252 HCRTR2 http://identifiers.org/ensembl/ENSG00000137573 SULF1 http://purl.obolibrary.org/obo/NCBITaxon_186623 Actinopteri http://purl.obolibrary.org/obo/NCBITaxon_7898 Actinopterygii http://identifiers.org/ensembl/ENSG00000137709 POU2F3 http://purl.obolibrary.org/obo/NCBITaxon_1338369 Dipnotetrapodomorpha http://purl.obolibrary.org/obo/NCBITaxon_8287 Sarcopterygii http://identifiers.org/ensembl/ENSG00000137804 NUSAP1 http://purl.obolibrary.org/obo/NCBITaxon_32561 Sauria http://purl.obolibrary.org/obo/NCBITaxon_8457 Sauropsida http://identifiers.org/ensembl/ENSG00000139329 LUM http://purl.obolibrary.org/obo/NCBITaxon_436486 Dinosauria http://purl.obolibrary.org/obo/NCBITaxon_8492 Archosauria http://identifiers.org/ensembl/ENSG00000140538 NTRK3 http://identifiers.org/ensembl/ENSG00000143171 RXRG http://purl.obolibrary.org/obo/NCBITaxon_6656 Arthropoda http://purl.obolibrary.org/obo/NCBITaxon_88770 Panarthropoda http://identifiers.org/ensembl/ENSG00000143196 DPT http://purl.obolibrary.org/obo/NCBITaxon_7742 Vertebrata http://purl.obolibrary.org/obo/NCBITaxon_89593 Craniata http://identifiers.org/ensembl/ENSG00000144227 NXPH2 http://purl.obolibrary.org/obo/NCBITaxon_1437010 Boreoeutheria http://purl.obolibrary.org/obo/NCBITaxon_9347 Eutheria http://identifiers.org/ensembl/ENSG00000144229 THSD7B http://purl.obolibrary.org/obo/NCBITaxon_1963758 Myomorpha http://purl.obolibrary.org/obo/NCBITaxon_9989 Rodentia http://identifiers.org/ensembl/ENSG00000145730 PAM http://purl.obolibrary.org/obo/UBERON_0005205 lamina propria of vagina http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure http://identifiers.org/ensembl/ENSG00000146469 VIP http://identifiers.org/ensembl/ENSG00000149591 TAGLN http://purl.obolibrary.org/obo/UBERON_0002834 cervical dorsal root ganglion http://purl.obolibrary.org/obo/UBERON_0000044 dorsal root ganglion http://identifiers.org/ensembl/ENSG00000152818 UTRN http://purl.obolibrary.org/obo/UBERON_0002837 sacral dorsal root ganglion http://purl.obolibrary.org/obo/UBERON_0000044 dorsal root ganglion http://identifiers.org/ensembl/ENSG00000154080 CHST9 http://purl.obolibrary.org/obo/UBERON_0009856 sac http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure http://identifiers.org/ensembl/ENSG00000154102 C16orf74 http://identifiers.org/ensembl/ENSG00000156395 SORCS3 http://purl.obolibrary.org/obo/UBERON_0018254 skeletal musculature http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure http://identifiers.org/ensembl/ENSG00000156689 GLYATL2 http://purl.obolibrary.org/obo/UBERON_0009911 lobule http://purl.obolibrary.org/obo/UBERON_0000063 organ subunit http://identifiers.org/ensembl/ENSG00000157005 SST http://purl.obolibrary.org/obo/UBERON_0001726 papilla of tongue http://purl.obolibrary.org/obo/UBERON_0000064 organ part http://identifiers.org/ensembl/ENSG00000157404 KIT http://purl.obolibrary.org/obo/UBERON_0002271 periventricular zone of hypothalamus http://purl.obolibrary.org/obo/UBERON_0000064 organ part http://identifiers.org/ensembl/ENSG00000162399 BSND http://purl.obolibrary.org/obo/UBERON_0002272 medial zone of hypothalamus http://purl.obolibrary.org/obo/UBERON_0000064 organ part http://identifiers.org/ensembl/ENSG00000163377 TAFA4 http://purl.obolibrary.org/obo/UBERON_0002273 lateral zone of hypothalamus http://purl.obolibrary.org/obo/UBERON_0000064 organ part http://identifiers.org/ensembl/ENSG00000163735 CXCL5 http://identifiers.org/ensembl/ENSG00000164120 HPGD http://purl.obolibrary.org/obo/UBERON_0003978 valve http://purl.obolibrary.org/obo/UBERON_0000064 organ part http://identifiers.org/ensembl/ENSG00000164330 EBF1 http://purl.obolibrary.org/obo/UBERON_0009089 inner medulla descending vasa recta http://purl.obolibrary.org/obo/UBERON_0000064 organ part http://identifiers.org/ensembl/ENSG00000166803 PCLAF http://purl.obolibrary.org/obo/UBERON_0009090 outer medulla descending vasa recta http://purl.obolibrary.org/obo/UBERON_0000064 organ part http://identifiers.org/ensembl/ENSG00000166959 MS4A8 http://purl.obolibrary.org/obo/UBERON_0009091 ascending vasa recta http://purl.obolibrary.org/obo/UBERON_0000064 organ part http://identifiers.org/ensembl/ENSG00000167306 MYO5B http://purl.obolibrary.org/obo/UBERON_0009092 inner medulla ascending vasa recta http://purl.obolibrary.org/obo/UBERON_0000064 organ part http://identifiers.org/ensembl/ENSG00000168079 SCARA5 http://purl.obolibrary.org/obo/UBERON_0009093 outer medulla ascending vasa recta http://purl.obolibrary.org/obo/UBERON_0000064 organ part http://identifiers.org/ensembl/ENSG00000170323 FABP4 http://identifiers.org/ensembl/ENSG00000171303 KCNK3 http://purl.obolibrary.org/obo/UBERON_0009095 tip of renal papilla http://purl.obolibrary.org/obo/UBERON_0000064 organ part http://identifiers.org/ensembl/ENSG00000171346 KRT15 http://purl.obolibrary.org/obo/UBERON_0009202 descending vasa recta http://purl.obolibrary.org/obo/UBERON_0000064 organ part http://identifiers.org/ensembl/ENSG00000171587 DSCAM http://identifiers.org/ensembl/ENSG00000171848 RRM2 http://purl.obolibrary.org/obo/UBERON_0009753 adrenal gland cortex zone http://purl.obolibrary.org/obo/UBERON_0000064 organ part http://identifiers.org/ensembl/ENSG00000171951 SCG2 http://purl.obolibrary.org/obo/UBERON_0010071 layer of tympanic membrane http://purl.obolibrary.org/obo/UBERON_0000064 organ part http://identifiers.org/ensembl/ENSG00000172673 THEMIS http://purl.obolibrary.org/obo/UBERON_0013522 subdivision of tube http://purl.obolibrary.org/obo/UBERON_0000064 organ part http://identifiers.org/ensembl/ENSG00000174501 ANKRD36C http://purl.obolibrary.org/obo/UBERON_3010706 lateral line nucleus http://purl.obolibrary.org/obo/UBERON_0000064 organ part http://identifiers.org/ensembl/ENSG00000174807 CD248 http://identifiers.org/ensembl/ENSG00000174948 GPR149 http://purl.obolibrary.org/obo/UBERON_0011159 primary subdivision of cranial skeletal system http://purl.obolibrary.org/obo/UBERON_0000075 subdivision of skeletal system http://identifiers.org/ensembl/ENSG00000175063 UBE2C http://purl.obolibrary.org/obo/UBERON_0012072 palatal part of dermatocranium http://purl.obolibrary.org/obo/UBERON_0000075 subdivision of skeletal system http://identifiers.org/ensembl/ENSG00000175497 DPP10 http://purl.obolibrary.org/obo/UBERON_0000112 sexually immature stage http://purl.obolibrary.org/obo/UBERON_0000105 life cycle stage http://identifiers.org/ensembl/ENSG00000176009 ASCL3 http://identifiers.org/ensembl/ENSG00000178031 ADAMTSL1 http://purl.obolibrary.org/obo/UBERON_0002464 nerve trunk http://purl.obolibrary.org/obo/UBERON_0000122 neuron projection bundle http://identifiers.org/ensembl/ENSG00000178538 CA8 http://purl.obolibrary.org/obo/UBERON_0019042 reproductive system mucosa http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure http://identifiers.org/ensembl/ENSG00000178568 ERBB4 http://purl.obolibrary.org/obo/UBERON_0001978 parenchyma of pancreas http://purl.obolibrary.org/obo/UBERON_0000353 parenchyma http://identifiers.org/ensembl/ENSG00000179902 C1orf194 http://purl.obolibrary.org/obo/UBERON_0019190 mucous gland of lung http://purl.obolibrary.org/obo/UBERON_0036225 respiratory system gland http://identifiers.org/ensembl/ENSG00000180801 ARSJ http://purl.obolibrary.org/obo/UBERON_0005945 neurocranial trabecula http://purl.obolibrary.org/obo/UBERON_0003932 cartilage element of chondrocranium http://identifiers.org/ensembl/ENSG00000183662 TAFA1 http://identifiers.org/ensembl/ENSG00000184005 ST6GALNAC3 http://purl.obolibrary.org/obo/UBERON_0001971 gastric juice http://purl.obolibrary.org/obo/UBERON_0000456 secretion of exocrine gland http://identifiers.org/ensembl/ENSG00000184530 C6orf58 http://purl.obolibrary.org/obo/UBERON_0010061 lumen of nasopharynx http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space http://identifiers.org/ensembl/ENSG00000185668 POU3F1 http://purl.obolibrary.org/obo/UBERON_0012466 extraembryonic cavity http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space http://identifiers.org/ensembl/ENSG00000185942 NKAIN3 http://purl.obolibrary.org/obo/UBERON_0014466 subarachnoid fissure http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space http://purl.obolibrary.org/obo/UBERON_0034905 gland lumen http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space http://identifiers.org/ensembl/ENSG00000187908 DMBT1 http://identifiers.org/ensembl/ENSG00000189056 RELN http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure http://purl.obolibrary.org/obo/UBERON_0000465 material anatomical entity http://purl.obolibrary.org/obo/UBERON_0000153 anterior region of body http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision http://identifiers.org/ensembl/ENSG00000189058 APOD http://identifiers.org/ensembl/ENSG00000196090 PTPRT http://purl.obolibrary.org/obo/UBERON_0000154 posterior region of body http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision http://identifiers.org/ensembl/ENSG00000196569 LAMA2 http://purl.obolibrary.org/obo/UBERON_0001444 subdivision of head http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision http://identifiers.org/ensembl/ENSG00000197085 NPSR1-AS1 http://purl.obolibrary.org/obo/UBERON_0009569 subdivision of trunk http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision http://identifiers.org/ensembl/ENSG00000197353 LYPD2 http://purl.obolibrary.org/obo/UBERON_0011860 collection of collagen fibrils http://purl.obolibrary.org/obo/UBERON_0000476 acellular anatomical structure http://identifiers.org/ensembl/ENSG00000197943 PLCG2 http://identifiers.org/ensembl/ENSG00000198691 ABCA4 http://purl.obolibrary.org/obo/UBERON_2005227 protoneuromast http://purl.obolibrary.org/obo/UBERON_0000477 anatomical cluster http://identifiers.org/ensembl/ENSG00000198901 PRC1 http://purl.obolibrary.org/obo/UBERON_0003254 amniotic ectoderm http://purl.obolibrary.org/obo/UBERON_0005292 extraembryonic tissue http://identifiers.org/ensembl/ENSG00000198963 RORB http://identifiers.org/ensembl/ENSG00000204262 COL5A2 http://purl.obolibrary.org/obo/UBERON_0005497 non-neural ectoderm http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure http://identifiers.org/ensembl/ENSG00000204305 AGER http://purl.obolibrary.org/obo/UBERON_0005933 hair root sheath http://purl.obolibrary.org/obo/UBERON_0000479 tissue http://identifiers.org/ensembl/ENSG00000206073 SERPINB4 http://purl.obolibrary.org/obo/UBERON_0010536 nephron progenitor http://purl.obolibrary.org/obo/UBERON_0000479 tissue http://identifiers.org/ensembl/ENSG00000215182 MUC5AC http://identifiers.org/ensembl/ENSG00000227681 AL033504.1 http://purl.obolibrary.org/obo/UBERON_0015757 heterogeneous tissue http://purl.obolibrary.org/obo/UBERON_0000479 tissue http://identifiers.org/ensembl/ENSG00000235665 LINC00298 http://purl.obolibrary.org/obo/UBERON_2000228 lateral line primordium http://purl.obolibrary.org/obo/UBERON_0000479 tissue http://identifiers.org/ensembl/ENSG00000242021 AC112493.1 http://purl.obolibrary.org/obo/UBERON_0012361 internal anal region http://purl.obolibrary.org/obo/UBERON_0000481 multi-tissue structure http://identifiers.org/ensembl/ENSG00000242265 PEG10 http://purl.obolibrary.org/obo/UBERON_0012469 external anal region http://purl.obolibrary.org/obo/UBERON_0000481 multi-tissue structure http://identifiers.org/ensembl/ENSG00000243004 ENSG00000243004;AC005062.2;AC005062.1 http://identifiers.org/ensembl/ENSG00000249803 AC112178.1 http://purl.obolibrary.org/obo/UBERON_0019304 sensory organ epithelium http://purl.obolibrary.org/obo/UBERON_0000483 epithelium http://identifiers.org/ensembl/ENSG00000250971 AC110772.2 http://purl.obolibrary.org/obo/UBERON_2001431 primitive olfactory epithelium http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue http://identifiers.org/ensembl/ENSG00000256193 LINC00507 http://identifiers.org/ensembl/ENSG00000264630 PRKCA-AS1 http://purl.obolibrary.org/obo/UBERON_0006930 glandular cuboidal epithelium http://purl.obolibrary.org/obo/UBERON_0006799 glandular epithelium http://identifiers.org/ensembl/ENSG00000265485 LINC01915 http://purl.obolibrary.org/obo/UBERON_0010025 dorsal part of pharyngeal pouch 3 http://purl.obolibrary.org/obo/UBERON_0015833 foregut epithelium http://identifiers.org/ensembl/ENSG00000267109 AC011990.1 http://purl.obolibrary.org/obo/UBERON_0010026 ventral part of pharyngeal pouch 3 http://purl.obolibrary.org/obo/UBERON_0015833 foregut epithelium http://identifiers.org/ensembl/ENSG00000271860 AL589740.1 http://identifiers.org/ensembl/ENSG00000275443 AC012409.2 http://purl.obolibrary.org/obo/UBERON_0010027 dorsal part of pharyngeal pouch 4 http://purl.obolibrary.org/obo/UBERON_0015833 foregut epithelium http://identifiers.org/ensembl/ENSG00000278254 AC004852.2 http://purl.obolibrary.org/obo/UBERON_0010028 ventral part of pharyngeal pouch 4 http://purl.obolibrary.org/obo/UBERON_0015833 foregut epithelium http://purl.obolibrary.org/obo/CL_4023083 obsolete chandelier cell http://purl.obolibrary.org/obo/UBERON_0011272 embryonic skin basal layer http://purl.obolibrary.org/obo/UBERON_0000490 unilaminar epithelium http://identifiers.org/ensembl/ENSMUSG00000109994 Gm45459 (Mmus) http://purl.obolibrary.org/obo/UBERON_0011592 future upper lip http://purl.obolibrary.org/obo/UBERON_0003235 epithelium of upper jaw http://identifiers.org/ncbigene/10716 TBR1 http://identifiers.org/ncbigene/11281 POU6F2 http://purl.obolibrary.org/obo/UBERON_0011596 future lower lip http://purl.obolibrary.org/obo/UBERON_0003236 epithelium of lower jaw http://identifiers.org/ncbigene/1310 COL19A1 http://purl.obolibrary.org/obo/UBERON_0012313 1st arch maxillary ectoderm http://purl.obolibrary.org/obo/UBERON_0015833 foregut epithelium http://identifiers.org/ncbigene/131034 CPNE4 http://identifiers.org/ncbigene/1395 CRHR2 http://purl.obolibrary.org/obo/UBERON_0004468 set of muscles of vertebral column http://purl.obolibrary.org/obo/UBERON_0001015 musculature http://identifiers.org/ncbigene/1812 DRD1 http://purl.obolibrary.org/obo/UBERON_0034729 sympathetic nerve http://purl.obolibrary.org/obo/UBERON_0001021 nerve http://identifiers.org/ncbigene/1813 DRD2 http://purl.obolibrary.org/obo/UBERON_0006224 elbow joint primordium http://purl.obolibrary.org/obo/UBERON_0001048 primordium http://identifiers.org/ncbigene/24141 LAMP5 http://identifiers.org/ncbigene/2571 GAD1 http://purl.obolibrary.org/obo/UBERON_0006227 ethmoid bone primordium http://purl.obolibrary.org/obo/UBERON_0001048 primordium http://identifiers.org/ncbigene/2572 GAD2 http://purl.obolibrary.org/obo/UBERON_0006236 tetrapod frontal bone primordium http://purl.obolibrary.org/obo/UBERON_0001048 primordium http://identifiers.org/ncbigene/26468 LHX6 http://identifiers.org/ncbigene/27086 FOXP1 http://purl.obolibrary.org/obo/UBERON_0006256 knee joint primordium http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure http://identifiers.org/ncbigene/2893 GRIA4 http://purl.obolibrary.org/obo/UBERON_0008801 parotid gland primordium http://purl.obolibrary.org/obo/UBERON_0001048 primordium http://purl.obolibrary.org/obo/UBERON_0008947 respiratory primordium http://purl.obolibrary.org/obo/UBERON_0001048 primordium http://identifiers.org/ncbigene/2897 GRIK1 http://identifiers.org/ncbigene/29091 STXBP6 http://purl.obolibrary.org/obo/UBERON_0010375 pancreas dorsal primordium http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure http://identifiers.org/ncbigene/30820 KCNIP1 http://purl.obolibrary.org/obo/UBERON_0010376 pancreas ventral primordium http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure http://identifiers.org/ncbigene/3736 KCNA1 http://purl.obolibrary.org/obo/UBERON_0000219 vertebral foramen of atlas http://purl.obolibrary.org/obo/UBERON_0005744 bone foramen http://identifiers.org/ncbigene/395 ARHGAP6 http://purl.obolibrary.org/obo/UBERON_0022357 mesentery of ileum http://purl.obolibrary.org/obo/UBERON_0001170 mesentery of small intestine http://identifiers.org/ncbigene/4212 MEIS2 http://purl.obolibrary.org/obo/UBERON_0007685 region of nephron tubule http://purl.obolibrary.org/obo/UBERON_0001231 nephron tubule http://identifiers.org/ncbigene/4852 NPY http://identifiers.org/ncbigene/4861 NPAS1 http://purl.obolibrary.org/obo/UBERON_0022281 epithelium of crypt of Lieberkuhn of large intestine http://purl.obolibrary.org/obo/UBERON_0011184 epithelium of crypt of Lieberkuhn http://identifiers.org/ncbigene/4929 NR4A2 http://purl.obolibrary.org/obo/UBERON_0005458 left umbilical artery http://purl.obolibrary.org/obo/UBERON_0001310 umbilical artery http://identifiers.org/ncbigene/5079 PAX5 http://purl.obolibrary.org/obo/UBERON_0005470 right umbilical artery http://purl.obolibrary.org/obo/UBERON_0001310 umbilical artery http://identifiers.org/ncbigene/54796 BNC2 http://purl.obolibrary.org/obo/UBERON_0001425 pectoral lymphatic vessel http://purl.obolibrary.org/obo/UBERON_0001473 lymphatic vessel http://identifiers.org/ncbigene/55553 SOX6 http://identifiers.org/ncbigene/57084 SLC17A6 http://purl.obolibrary.org/obo/UBERON_0008202 bone of hip region http://purl.obolibrary.org/obo/UBERON_0001474 bone element http://identifiers.org/ncbigene/5744 PTHLH http://purl.obolibrary.org/obo/UBERON_0012175 acoustico-facial VII-VIII ganglion complex http://purl.obolibrary.org/obo/UBERON_0010313 neural crest-derived structure http://identifiers.org/ncbigene/5816 PVALB http://purl.obolibrary.org/obo/UBERON_0013498 vestibulo-cochlear VIII ganglion complex http://purl.obolibrary.org/obo/UBERON_0001714 cranial ganglion http://identifiers.org/ncbigene/64919 BCL11B http://identifiers.org/ncbigene/6496 SIX3 http://purl.obolibrary.org/obo/UBERON_0002830 anteroventral cochlear nucleus http://purl.obolibrary.org/obo/UBERON_0001720 cochlear nucleus http://purl.obolibrary.org/obo/UBERON_0002831 posteroventral cochlear nucleus http://purl.obolibrary.org/obo/UBERON_0001720 cochlear nucleus http://purl.obolibrary.org/obo/UBERON_0000444 lymphoid follicle http://purl.obolibrary.org/obo/UBERON_0001744 lymphoid tissue http://purl.obolibrary.org/obo/UBERON_0012069 epithelium-associated lymphoid tissue http://purl.obolibrary.org/obo/UBERON_0001744 lymphoid tissue http://identifiers.org/ncbigene/6531 SLC6A3 http://purl.obolibrary.org/obo/UBERON_0007619 limiting membrane of retina http://purl.obolibrary.org/obo/UBERON_0001781 layer of retina http://purl.obolibrary.org/obo/UBERON_0001809 enteric ganglion http://purl.obolibrary.org/obo/UBERON_0001808 parasympathetic ganglion http://identifiers.org/ncbigene/6752 SSTR2 http://purl.obolibrary.org/obo/UBERON_0022280 epithelium of crypt of Lieberkuhn of small intestine http://purl.obolibrary.org/obo/UBERON_0011184 epithelium of crypt of Lieberkuhn http://identifiers.org/ncbigene/7054 TH http://purl.obolibrary.org/obo/UBERON_0019189 carotid artery endothelium http://purl.obolibrary.org/obo/UBERON_0001917 endothelium of artery http://identifiers.org/ncbigene/7432 VIP http://purl.obolibrary.org/obo/UBERON_0019196 iliac artery endothelium http://purl.obolibrary.org/obo/UBERON_0001917 endothelium of artery http://identifiers.org/ncbigene/793 CALB1 http://purl.obolibrary.org/obo/UBERON_0005844 spinal cord segment http://purl.obolibrary.org/obo/UBERON_0001948 regional part of spinal cord http://identifiers.org/ncbigene/93986 FOXP2 http://purl.obolibrary.org/obo/UBERON_0022292 splenic arteriole http://purl.obolibrary.org/obo/UBERON_0003497 abdomen blood vessel http://identifiers.org/ncbigene/9547 CXCL14 http://purl.obolibrary.org/obo/UBERON_0010059 hypoglossal cord http://purl.obolibrary.org/obo/UBERON_0002036 striated muscle tissue http://identifiers.org/ncbigene/9705 ST18 http://purl.obolibrary.org/obo/UBERON_2001073 axial vasculature http://purl.obolibrary.org/obo/UBERON_0002049 vasculature http://identifiers.org/ncbigene/381925 Plpp4 (Mmus) http://purl.obolibrary.org/obo/UBERON_0003076 posterior neural tube http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure https://purl.brain-bican.org/ontology/mbao/MBA_370 Medulla, motor related http://purl.obolibrary.org/obo/UBERON_0003080 anterior neural tube http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure http://identifiers.org/ncbigene/51797 Ctps (Mmus) http://identifiers.org/ncbigene/14652 Glp1r (Mmus) http://identifiers.org/ncbigene/67701 Wfdc2 (Mmus) http://identifiers.org/ncbigene/19144 Klk6 (Mmus) http://identifiers.org/ncbigene/66353 Riiad1 (Mmus) http://identifiers.org/ncbigene/76088 Dock8 (Mmus) http://purl.obolibrary.org/obo/UBERON_0005092 right horn of sinus venosus http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure http://purl.obolibrary.org/obo/UBERON_0006218 common atrial chamber http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure http://identifiers.org/ncbigene/76438 Rftn1 (Mmus) http://purl.obolibrary.org/obo/UBERON_0006232 facio-acoustic VII-VIII preganglion complex http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure http://purl.obolibrary.org/obo/UBERON_0006260 lingual swellings http://purl.obolibrary.org/obo/UBERON_0010188 protuberance https://purl.brain-bican.org/ontology/mbao/MBA_728 arbor vitae http://purl.obolibrary.org/obo/UBERON_0007237 1st arch mandibular component http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure http://purl.obolibrary.org/obo/UBERON_0007238 1st arch maxillary component http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure http://purl.obolibrary.org/obo/CL_0008023 obsolete cardiac fibroblast http://purl.obolibrary.org/obo/UBERON_0010316 germ layer / neural crest http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue http://purl.obolibrary.org/obo/UBERON_0010963 trunk and cervical myotome group http://purl.obolibrary.org/obo/UBERON_0003082 myotome http://purl.obolibrary.org/obo/UBERON_0009664 gut mesentery http://purl.obolibrary.org/obo/UBERON_0002095 mesentery http://purl.obolibrary.org/obo/CP_0000025 obsolete CP:0000025 http://purl.obolibrary.org/obo/UBERON_0033939 sacral spinal cord dorsal horn http://purl.obolibrary.org/obo/UBERON_0002256 dorsal horn of spinal cord http://purl.obolibrary.org/obo/UBERON_0030276 lumbar spinal cord ventral horn http://purl.obolibrary.org/obo/UBERON_0002257 ventral horn of spinal cord http://purl.obolibrary.org/obo/UBERON_0032748 sacral spinal cord ventral horn http://purl.obolibrary.org/obo/UBERON_0002257 ventral horn of spinal cord http://purl.obolibrary.org/obo/CP_0000039 obsolete CP:0000039 http://purl.obolibrary.org/obo/UBERON_0034730 olfactory tract linking bulb to ipsilateral dorsal telencephalon http://purl.obolibrary.org/obo/UBERON_0002265 olfactory tract http://purl.obolibrary.org/obo/UBERON_2000238 olfactory tract linking bulb to ipsilateral ventral telencephalon http://purl.obolibrary.org/obo/UBERON_0002265 olfactory tract http://purl.obolibrary.org/obo/CP_0000040 obsolete CP:0000040 http://purl.obolibrary.org/obo/UBERON_0022315 primary motor cortex layer 5 http://purl.obolibrary.org/obo/UBERON_0002301 layer of neocortex http://purl.obolibrary.org/obo/CP_0000043 obsolete CP:0000043 http://purl.obolibrary.org/obo/UBERON_0005367 hippocampus granule cell layer http://purl.obolibrary.org/obo/UBERON_0002305 layer of hippocampus http://purl.obolibrary.org/obo/D96882F1-8709-49AB-BCA9-772A67EA6C33 obsolete D96882F1-8709-49AB-BCA9-772A67EA6C33 http://purl.obolibrary.org/obo/UBERON_0029503 sacral spinal cord gray matter http://purl.obolibrary.org/obo/UBERON_0002315 gray matter of spinal cord https://purl.brain-bican.org/ontology/mbao/MBA_1117 Pons, behavioral state related http://purl.obolibrary.org/obo/UBERON_0029636 lumbar spinal cord gray matter http://purl.obolibrary.org/obo/UBERON_0002315 gray matter of spinal cord http://purl.obolibrary.org/obo/UBERON_0007417 peduncle of neuraxis http://purl.obolibrary.org/obo/UBERON_0002316 white matter http://identifiers.org/ncbigene/58187 Cldn10 (Mmus) https://purl.brain-bican.org/ontology/mbao/MBA_1132 Pons, sensory related http://purl.obolibrary.org/obo/UBERON_0026246 sacral spinal cord white matter http://purl.obolibrary.org/obo/UBERON_0002318 white matter of spinal cord https://purl.brain-bican.org/ontology/mbao/MBA_21 lateral olfactory tract, general http://purl.obolibrary.org/obo/UBERON_0026386 lumbar spinal cord white matter http://purl.obolibrary.org/obo/UBERON_0002318 white matter of spinal cord https://purl.brain-bican.org/ontology/mbao/MBA_323 Midbrain, motor related http://identifiers.org/ncbigene/216961 Coro6 (Mmus) http://purl.obolibrary.org/obo/UBERON_0009708 dorsal pancreas http://purl.obolibrary.org/obo/UBERON_0005177 trunk region element http://identifiers.org/ncbigene/75823 Fam227b (Mmus) http://purl.obolibrary.org/obo/UBERON_0009709 ventral pancreas http://purl.obolibrary.org/obo/UBERON_0005177 trunk region element http://identifiers.org/ncbigene/16840 Cnmd (Mmus) http://purl.obolibrary.org/obo/UBERON_0011648 jaw muscle http://purl.obolibrary.org/obo/UBERON_0002376 cranial muscle http://identifiers.org/ncbigene/69239 Pdzph1 (Mmus) http://identifiers.org/ncbigene/109648 Npy (Mmus) http://purl.obolibrary.org/obo/UBERON_0015789 cranial or facial muscle http://purl.obolibrary.org/obo/UBERON_0002376 cranial muscle http://identifiers.org/ncbigene/14580 Gfap (Mmus) http://purl.obolibrary.org/obo/UBERON_0008187 hypertrophic cartilage zone http://purl.obolibrary.org/obo/UBERON_0002418 cartilage tissue https://purl.brain-bican.org/ontology/mbao/MBA_856 Thalamus, polymodal association cortex related http://purl.obolibrary.org/obo/UBERON_0019206 tongue papilla epithelium http://purl.obolibrary.org/obo/UBERON_0003357 epithelium of tongue http://purl.obolibrary.org/obo/UBERON_0016527 white matter of cerebral lobe http://purl.obolibrary.org/obo/UBERON_0002437 cerebral hemisphere white matter http://identifiers.org/ncbigene/20963 Syk (Mmus) http://purl.obolibrary.org/obo/CLM_5050484 LAMP5, CXCL14 (CAS evidence). http://purl.obolibrary.org/obo/UBERON_0034678 forceps minor of corpus callosum http://purl.obolibrary.org/obo/UBERON_0002437 cerebral hemisphere white matter http://purl.obolibrary.org/obo/CLM_5050485 LAMP5, LHX6 (CAS evidence). http://purl.obolibrary.org/obo/CLM_5050493 GAD1, GAD2, FOXP2, MEIS2, NPAS1 (CAS evidence). http://purl.obolibrary.org/obo/UBERON_0001318 inferior vesical vein http://purl.obolibrary.org/obo/UBERON_0002460 vesical vein http://purl.obolibrary.org/obo/UBERON_0006355 superior vesical vein http://purl.obolibrary.org/obo/UBERON_0002460 vesical vein http://purl.obolibrary.org/obo/CLM_5050494 SOX6, KCNA1 (CAS evidence). http://purl.obolibrary.org/obo/UBERON_0002004 trunk of sciatic nerve http://purl.obolibrary.org/obo/UBERON_0002464 nerve trunk http://purl.obolibrary.org/obo/CLM_5050495 Pvalb (CAS evidence). http://purl.obolibrary.org/obo/CLM_5050496 Sst, Tbr1, Slc17a6 (CAS evidence). http://purl.obolibrary.org/obo/UBERON_0002442 axillary nerve trunk http://purl.obolibrary.org/obo/UBERON_0002464 nerve trunk http://purl.obolibrary.org/obo/CLM_5050504 DRD1, CPNE4 (CAS evidence). http://purl.obolibrary.org/obo/UBERON_0016413 medullary cavity of long bone http://purl.obolibrary.org/obo/UBERON_0002484 bone marrow cavity http://purl.obolibrary.org/obo/CLM_5050509 TH, CALB1, SLC6A3, NR4A2, BNC2 (CAS evidence). http://purl.obolibrary.org/obo/UBERON_0015860 visceral abdominal lymph node http://purl.obolibrary.org/obo/UBERON_0002507 abdominal lymph node http://purl.obolibrary.org/obo/CLM_5050511 TH, GAD2 (CAS evidence). http://purl.obolibrary.org/obo/CLM_5050512 PAX5, BCL11B, POU6F2 (CAS evidence). http://purl.obolibrary.org/obo/UBERON_0008837 palmar/plantar part of autopod http://purl.obolibrary.org/obo/UBERON_0002529 limb segment http://purl.obolibrary.org/obo/CLM_5050513 SIX3, FOXP1 (CAS evidence). http://purl.obolibrary.org/obo/UBERON_0012139 segment of autopod http://purl.obolibrary.org/obo/UBERON_0002529 limb segment http://purl.obolibrary.org/obo/UBERON_0000963 head sensillum http://purl.obolibrary.org/obo/UBERON_0002536 arthropod sensillum http://purl.obolibrary.org/obo/CLM_5050515 TH, SOX6 (CAS evidence). http://purl.obolibrary.org/obo/CLM_5050520 ST18, PTHLH, COL19A1 (CAS evidence). http://purl.obolibrary.org/obo/UBERON_0003116 pharyngeal arch 5 http://purl.obolibrary.org/obo/UBERON_0002539 pharyngeal arch http://purl.obolibrary.org/obo/CLM_5050523 NPY (CAS evidence). http://purl.obolibrary.org/obo/UBERON_0002558 organ cavity http://purl.obolibrary.org/obo/UBERON_0002553 anatomical cavity http://purl.obolibrary.org/obo/UBERON_0005606 hyaloid cavity http://purl.obolibrary.org/obo/UBERON_0012467 enclosed anatomical space http://purl.obolibrary.org/obo/CLM_5050525 ST18 (CAS evidence). http://purl.obolibrary.org/obo/CLM_5050527 VIP (CAS evidence). http://purl.obolibrary.org/obo/UBERON_0011565 lumen of gastrointestinal system http://purl.obolibrary.org/obo/UBERON_0002553 anatomical cavity http://purl.obolibrary.org/obo/CLM_5050529 DRD1, STXBP6 (CAS evidence). http://purl.obolibrary.org/obo/UBERON_0002550 anterior hypothalamic region http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain http://purl.obolibrary.org/obo/UBERON_0004703 dorsal thalamus http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain http://purl.obolibrary.org/obo/CLM_5050530 DRD1, KCNIP1 (CAS evidence). http://purl.obolibrary.org/obo/CLM_5050531 DRD1, DRD2, CRHR2, GRIK1 (CAS evidence). http://purl.obolibrary.org/obo/UBERON_0022230 retrohippocampal region http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain http://purl.obolibrary.org/obo/CLM_5050532 DRD2, STXBP6 (CAS evidence). https://purl.brain-bican.org/ontology/mbao/MBA_701 Vestibular nuclei http://purl.obolibrary.org/obo/UBERON_0002673 vestibular nuclear complex http://purl.obolibrary.org/obo/CLM_5050534 DRD2, KCNIP1 (CAS evidence). http://purl.obolibrary.org/obo/UBERON_0027331 flocculonodular lobe, hemisphere portion http://purl.obolibrary.org/obo/UBERON_0002749 regional part of cerebellar cortex http://purl.obolibrary.org/obo/CLM_5050536 DRD1, ARHGAP6 (CAS evidence). http://purl.obolibrary.org/obo/UBERON_0005502 rhombomere roof plate http://purl.obolibrary.org/obo/UBERON_0003054 roof plate http://purl.obolibrary.org/obo/CLM_5050537 DRD1, GRIA4 (CAS evidence). http://purl.obolibrary.org/obo/UBERON_2001156 posterior lateral line placode http://purl.obolibrary.org/obo/UBERON_0003067 dorsolateral placode http://purl.obolibrary.org/obo/CLM_5050538 DRD2, ARHGAP6 (CAS evidence). http://purl.obolibrary.org/obo/UBERON_0005113 metanephric cortex mesenchyme http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure http://purl.obolibrary.org/obo/CLM_5050544 SLC17A6 (CAS evidence). http://purl.obolibrary.org/obo/UBERON_0006210 body-wall mesenchyme http://purl.obolibrary.org/obo/UBERON_0003104 mesenchyme https://purl.brain-bican.org/ontology/dhbao/DHBA_10343 external segment of globus pallidus http://purl.obolibrary.org/obo/UBERON_0007690 early pharyngeal endoderm http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue http://purl.obolibrary.org/obo/UBERON_0013156 1st arch mandibular endoderm http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue https://purl.brain-bican.org/ontology/dhbao/DHBA_10301 subicular cortex https://purl.brain-bican.org/ontology/dhbao/DHBA_10406 lateral nuclear complex of thalamus http://purl.obolibrary.org/obo/UBERON_0006230 extrinsic ocular pre-muscle mass http://purl.obolibrary.org/obo/UBERON_0005865 pre-muscle condensation https://purl.brain-bican.org/ontology/dhbao/DHBA_10416 ventral group of lateral nucleus http://purl.obolibrary.org/obo/UBERON_0006292 shoulder joint primordium http://purl.obolibrary.org/obo/UBERON_0005856 developing mesenchymal condensation https://purl.brain-bican.org/ontology/dhbao/DHBA_10465 subthalamus http://purl.obolibrary.org/obo/UBERON_0005667 connecting stalk mesoderm http://purl.obolibrary.org/obo/UBERON_0007524 dense mesenchyme tissue https://purl.brain-bican.org/ontology/dhbao/DHBA_10468 preoptic region of HTH http://purl.obolibrary.org/obo/UBERON_0017635 paired venous dural sinus http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure https://purl.brain-bican.org/ontology/dhbao/DHBA_10469 periventricular nucleus, preoptic portion https://purl.brain-bican.org/ontology/dhbao/DHBA_10473 supraoptic region of HTH http://purl.obolibrary.org/obo/UBERON_0009967 spleen venous sinus http://purl.obolibrary.org/obo/UBERON_0006615 venous sinus https://purl.brain-bican.org/ontology/dhbao/DHBA_10483 tuberal region of HTH http://purl.obolibrary.org/obo/UBERON_0019263 gray matter of hindbrain http://purl.obolibrary.org/obo/UBERON_0003528 brain gray matter https://purl.brain-bican.org/ontology/dhbao/DHBA_10506 transient structures of forebrain http://purl.obolibrary.org/obo/UBERON_0019264 gray matter of forebrain http://purl.obolibrary.org/obo/UBERON_0003528 brain gray matter https://purl.brain-bican.org/ontology/dhbao/DHBA_10558 forebrain commissural fiber tracts https://purl.brain-bican.org/ontology/dhbao/DHBA_146034908 adjoining structures of forebrain ventricles http://purl.obolibrary.org/obo/UBERON_0019267 gray matter of midbrain http://purl.obolibrary.org/obo/UBERON_0003528 brain gray matter https://purl.brain-bican.org/ontology/dhbao/DHBA_10609 surface structures of forebrain http://purl.obolibrary.org/obo/UBERON_0009644 trachea non-cartilage connective tissue http://purl.obolibrary.org/obo/UBERON_0003571 trachea connective tissue https://purl.brain-bican.org/ontology/dhbao/DHBA_10611 primary sulci http://purl.obolibrary.org/obo/UBERON_0011766 left recurrent laryngeal nerve http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure http://purl.obolibrary.org/obo/UBERON_0011767 right recurrent laryngeal nerve http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure https://purl.brain-bican.org/ontology/dhbao/DHBA_10652 surface structures of midbrain https://purl.brain-bican.org/ontology/dhbao/DHBA_10663 transient structures of hindbrain http://purl.obolibrary.org/obo/UBERON_0010687 pedal digit metatarsal pre-cartilage condensation http://purl.obolibrary.org/obo/UBERON_0015036 pedal digit metatarsal endochondral element https://purl.brain-bican.org/ontology/dhbao/DHBA_10669 ventricles of hindbrain http://purl.obolibrary.org/obo/UBERON_0006304 future trigeminal ganglion http://purl.obolibrary.org/obo/UBERON_0003869 presumptive ganglion https://purl.brain-bican.org/ontology/dhbao/DHBA_10670 surface structures of hindbrain http://purl.obolibrary.org/obo/UBERON_0001746 capsule of thyroid gland http://purl.obolibrary.org/obo/UBERON_0003893 capsule http://purl.obolibrary.org/obo/UBERON_0010894 keratinous tooth http://purl.obolibrary.org/obo/UBERON_0003913 tooth-like structure https://purl.brain-bican.org/ontology/dhbao/DHBA_12074 olfactory striae https://purl.brain-bican.org/ontology/dhbao/DHBA_12112 cerebral gyri and lobules http://purl.obolibrary.org/obo/UBERON_0010062 pharyngotympanic tube epithelium http://purl.obolibrary.org/obo/UBERON_0015813 middle ear epithelium https://purl.brain-bican.org/ontology/dhbao/DHBA_12196 efferent nuclei of the cranial nerves in the midbrain http://purl.obolibrary.org/obo/UBERON_0010065 auditory meatus epithelium http://purl.obolibrary.org/obo/UBERON_0015814 outer ear epithelium https://purl.brain-bican.org/ontology/dhbao/DHBA_146034938 ventral tegmental region of midbrain http://purl.obolibrary.org/obo/UBERON_0022235 peduncle of diencephalon http://purl.obolibrary.org/obo/UBERON_0007417 peduncle of neuraxis https://purl.brain-bican.org/ontology/dhbao/DHBA_12277 other nuclei in midbrain tegmentum http://purl.obolibrary.org/obo/UBERON_0016508 pelvic ganglion http://purl.obolibrary.org/obo/UBERON_0003964 prevertebral ganglion https://purl.brain-bican.org/ontology/dhbao/DHBA_12314 transient structures of midbrain https://purl.brain-bican.org/ontology/dhbao/DHBA_12319 intermediate (mantle) zone of midbrain http://purl.obolibrary.org/obo/UBERON_0009950 olfactory bulb plexiform layer http://purl.obolibrary.org/obo/UBERON_0004001 olfactory bulb layer http://purl.obolibrary.org/obo/UBERON_0005351 paraflocculus http://purl.obolibrary.org/obo/UBERON_0027331 flocculonodular lobe, hemisphere portion https://purl.brain-bican.org/ontology/dhbao/DHBA_12417 efferent nuclei of cranial nerves in pons https://purl.brain-bican.org/ontology/dhbao/DHBA_12436 afferent nuclei of cranial nerves in pons http://purl.obolibrary.org/obo/UBERON_0013160 epithalamus ventricular layer http://purl.obolibrary.org/obo/UBERON_0004060 neural tube ventricular layer https://purl.brain-bican.org/ontology/dhbao/DHBA_12453 auditory relay nuclei in pons http://purl.obolibrary.org/obo/UBERON_0034710 spinal cord ventricular layer http://purl.obolibrary.org/obo/UBERON_0004060 neural tube ventricular layer https://purl.brain-bican.org/ontology/dhbao/DHBA_12471 raphe pontis nucleus http://purl.obolibrary.org/obo/UBERON_0009580 diencephalon mantle layer http://purl.obolibrary.org/obo/UBERON_0004061 neural tube mantle layer https://purl.brain-bican.org/ontology/dhbao/DHBA_12503 other nuclei in pontine tegmentum https://purl.brain-bican.org/ontology/dhbao/DHBA_12538 tegmentum of medulla oblongata http://purl.obolibrary.org/obo/UBERON_0009581 midbrain mantle layer http://purl.obolibrary.org/obo/UBERON_0004061 neural tube mantle layer http://purl.obolibrary.org/obo/UBERON_0009583 spinal cord mantle layer http://purl.obolibrary.org/obo/UBERON_0004061 neural tube mantle layer https://purl.brain-bican.org/ontology/dhbao/DHBA_12539 efferent nuclei of cranial nerves in the medulla oblongata http://purl.obolibrary.org/obo/UBERON_0013159 epithalamus mantle layer http://purl.obolibrary.org/obo/UBERON_0004061 neural tube mantle layer https://purl.brain-bican.org/ontology/dhbao/DHBA_12595 precerebellar nuclei https://purl.brain-bican.org/ontology/dhbao/DHBA_12666 rhombomere A http://purl.obolibrary.org/obo/UBERON_0034709 hindbrain marginal layer http://purl.obolibrary.org/obo/UBERON_0011215 central nervous system cell part cluster https://purl.brain-bican.org/ontology/dhbao/DHBA_12773 pyramidal tract http://purl.obolibrary.org/obo/UBERON_0005239 basal plate metencephalon http://purl.obolibrary.org/obo/UBERON_0004064 neural tube basal plate https://purl.brain-bican.org/ontology/dhbao/DHBA_146035012 adjoining structures of fourth ventricle http://purl.obolibrary.org/obo/UBERON_0005728 extraembryonic mesoderm http://purl.obolibrary.org/obo/UBERON_0007524 dense mesenchyme tissue https://purl.brain-bican.org/ontology/dhbao/DHBA_12827 surface structures of cerebellum http://purl.obolibrary.org/obo/UBERON_0009615 midbrain hindbrain boundary neural plate http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure https://purl.brain-bican.org/ontology/dhbao/DHBA_12837 cerebellar lobes and lobules https://purl.brain-bican.org/ontology/dhbao/DHBA_12856 surface structures of pons http://purl.obolibrary.org/obo/UBERON_0006173 pronephric proximal tubule http://purl.obolibrary.org/obo/UBERON_0005310 pronephric nephron tubule https://purl.brain-bican.org/ontology/dhbao/DHBA_12872 surface structures of medulla http://purl.obolibrary.org/obo/UBERON_0006175 pronephric distal tubule http://purl.obolibrary.org/obo/UBERON_0005310 pronephric nephron tubule https://purl.brain-bican.org/ontology/dhbao/DHBA_146035116 surface structures of spinal cord http://purl.obolibrary.org/obo/UBERON_0005339 outflow tract pulmonary component http://purl.obolibrary.org/obo/UBERON_0004145 outflow tract https://purl.brain-bican.org/ontology/mbao/MBA_896 thalamus related http://purl.obolibrary.org/obo/UBERON_0009196 indifferent external genitalia http://purl.obolibrary.org/obo/UBERON_0004176 external genitalia http://purl.obolibrary.org/obo/RO_0004009 has primary input http://purl.obolibrary.org/obo/RO_0002233 has input p has primary input c if (a) p has input c and (b) the goal of process is to modify, consume, or transform c. http://purl.obolibrary.org/obo/UBERON_0004912 biliary bud http://purl.obolibrary.org/obo/UBERON_0009854 digestive tract diverticulum http://purl.obolibrary.org/obo/RO_0040036 results in changes to anatomical or cellular structure http://purl.obolibrary.org/obo/RO_0000057 has participant p has anatomical participant c iff p has participant c, and c is an anatomical entity http://purl.obolibrary.org/obo/UBERON_0008836 liver bud http://purl.obolibrary.org/obo/UBERON_0009854 digestive tract diverticulum http://purl.obolibrary.org/obo/UBERON_0011222 intra-ocular muscle http://purl.obolibrary.org/obo/UBERON_0004277 eye muscle http://purl.obolibrary.org/obo/RO_0002100 has soma location http://purl.obolibrary.org/obo/RO_0002131 overlaps Relation between a neuron and a material anatomical entity that its soma is part of. http://purl.obolibrary.org/obo/RO_0002160 only in taxon http://purl.obolibrary.org/obo/RO_0002162 in taxon x only in taxon y if and only if x is in taxon y, and there is no other organism z such that y!=z a and x is in taxon z. http://purl.obolibrary.org/obo/UBERON_0034902 sacral sympathetic nerve trunk http://purl.obolibrary.org/obo/UBERON_0004295 sympathetic nerve trunk http://purl.obolibrary.org/obo/UBERON_0012416 respiratory system arterial smooth muscle http://purl.obolibrary.org/obo/UBERON_0004695 arterial system smooth muscle http://purl.obolibrary.org/obo/RO_0002258 developmentally preceded by http://purl.obolibrary.org/obo/RO_0002324 developmentally related to Candidate definition: x developmentally related to y if and only if there exists some developmental process (GO:0032502) p such that x and y both participates in p, and x is the output of p and y is the input of p http://purl.obolibrary.org/obo/UBERON_0013121 proximal epiphysis of phalanx of pes http://purl.obolibrary.org/obo/UBERON_0011973 epiphysis of phalanx of pes http://purl.obolibrary.org/obo/RO_0002234 has output http://purl.obolibrary.org/obo/RO_0000057 has participant p has output c iff c is a participant in p, c is present at the end of p, and c is not present in the same state at the beginning of p. http://purl.obolibrary.org/obo/UBERON_0018649 cardiac muscle tissue of ventricle http://purl.obolibrary.org/obo/UBERON_0004493 cardiac muscle tissue of myocardium http://purl.obolibrary.org/obo/RO_0002162 in taxon http://purl.obolibrary.org/obo/RO_0002320 evolutionarily related to x is in taxon y if an only if y is an organism, and the relationship between x and y is one of: part of (reflexive), developmentally preceded by, derives from, secreted by, expressed. http://purl.obolibrary.org/obo/UBERON_2001053 future internal carotid artery http://purl.obolibrary.org/obo/UBERON_0004573 systemic artery http://purl.obolibrary.org/obo/UBERON_0008339 microvascular endothelium http://purl.obolibrary.org/obo/UBERON_0004638 blood vessel endothelium http://purl.obolibrary.org/obo/RO_0002286 developmentally succeeded by http://purl.obolibrary.org/obo/RO_0002384 has developmental potential involving Inverse of developmentally preceded by http://purl.obolibrary.org/obo/UBERON_0012276 endometrium glandular epithelium http://purl.obolibrary.org/obo/UBERON_0007589 ciliated columnar oviduct epithelium http://purl.obolibrary.org/obo/RO_0002371 attached to http://purl.obolibrary.org/obo/RO_0002177 attached to part of a is attached to b if and only if a and b are discrete objects or object parts, and there are physical connections between a and b such that a force pulling a will move b, or a force pulling b will move a http://purl.obolibrary.org/obo/UBERON_0000158 membranous layer http://purl.obolibrary.org/obo/UBERON_0004923 organ component layer http://purl.obolibrary.org/obo/UBERON_0010291 layer of sclera http://purl.obolibrary.org/obo/UBERON_0004923 organ component layer http://purl.obolibrary.org/obo/RO_0002384 has developmental potential involving http://purl.obolibrary.org/obo/RO_0002324 developmentally related to x has developmental potential involving y iff x is capable of a developmental process with output y. y may be the successor of x, or may be a different structure in the vicinity (as for example in the case of developmental induction). http://purl.obolibrary.org/obo/UBERON_0011234 fibrous membrane of synovial tendon sheath http://purl.obolibrary.org/obo/UBERON_0004923 organ component layer http://purl.obolibrary.org/obo/UBERON_0018673 neck of fibula http://purl.obolibrary.org/obo/UBERON_0018664 neck of bone element http://purl.obolibrary.org/obo/RO_0002388 has potential to directly develop into http://purl.obolibrary.org/obo/RO_0002387 has potential to develop into x has potential to directly develop into y iff x directly develops into y or x is capable of directly developing into y http://purl.obolibrary.org/obo/UBERON_4200172 neck of humerus http://purl.obolibrary.org/obo/UBERON_0018664 neck of bone element http://purl.obolibrary.org/obo/RO_0002178 supplies http://purl.obolibrary.org/obo/RO_0002170 connected to Relation between an arterial structure and another structure, where the arterial structure acts as a conduit channeling fluid, substance or energy. http://purl.obolibrary.org/obo/UBERON_0005139 metanephric long descending thin limb http://purl.obolibrary.org/obo/UBERON_0005134 metanephric nephron epithelium http://purl.obolibrary.org/obo/RO_0002372 has muscle origin http://purl.obolibrary.org/obo/RO_0002567 biomechanically related to m has_muscle_origin s iff m is attached_to s, and it is the case that when m contracts, s does not move. The site of the origin tends to be more proximal and have greater mass than what the other end attaches to. http://purl.obolibrary.org/obo/UBERON_0006652 muscular layer of vagina http://purl.obolibrary.org/obo/UBERON_0006660 muscular coat http://purl.obolibrary.org/obo/RO_0002380 branching part of http://purl.obolibrary.org/obo/RO_0002375 in branching relationship with x is a branching part of y if and only if x is part of y and x is connected directly or indirectly to the main stem of y http://purl.obolibrary.org/obo/UBERON_0011945 luminal layer of epithelium http://purl.obolibrary.org/obo/UBERON_0005162 multi cell part structure http://purl.obolibrary.org/obo/RO_0002568 has muscle antagonist http://purl.obolibrary.org/obo/RO_0002567 biomechanically related to m1 has_muscle_antagonist m2 iff m1 has_muscle_insertion s, m2 has_muscle_insection s, m1 acts in opposition to m2, and m2 is responsible for returning the structure to its initial position. http://purl.obolibrary.org/obo/UBERON_0015410 heart plus pericardium http://purl.obolibrary.org/obo/UBERON_0005178 thoracic cavity element http://purl.obolibrary.org/obo/UBERON_0010189 right atrium venous valve http://purl.obolibrary.org/obo/UBERON_0006675 venous valve http://purl.obolibrary.org/obo/RO_0002569 has branching part http://purl.obolibrary.org/obo/RO_0002375 in branching relationship with inverse of branching part of http://purl.obolibrary.org/obo/UBERON_0009920 optic neural crest http://purl.obolibrary.org/obo/UBERON_0007530 migrating mesenchyme population http://purl.obolibrary.org/obo/UBERON_0009618 trunk paraxial mesoderm http://purl.obolibrary.org/obo/UBERON_0005256 trunk mesenchyme http://purl.obolibrary.org/obo/RO_0002571 lumen of http://purl.obolibrary.org/obo/BFO_0000050 part of x lumen_of y iff x is the space or substance that is part of y and does not cross any of the inner membranes or boundaries of y that is maximal with respect to the volume of the convex hull. http://purl.obolibrary.org/obo/UBERON_0009722 entire pharyngeal arch endoderm http://purl.obolibrary.org/obo/UBERON_0015833 foregut epithelium http://purl.obolibrary.org/obo/uberon/core#anteriorly_connected_to anteriorly connected to http://purl.obolibrary.org/obo/RO_0002170 connected to x anteriorly_connected_to y iff the anterior part of x is connected to y. i.e. x connected_to y and x posterior_to y. http://purl.obolibrary.org/obo/UBERON_0009881 anterior lateral plate mesoderm http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue http://purl.obolibrary.org/obo/UBERON_0009145 pharyngeal region of foregut http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure http://purl.obolibrary.org/obo/uberon/core#distally_connected_to distally connected to http://purl.obolibrary.org/obo/RO_0002170 connected to x distally_connected_to y iff the distal part of x is connected to y. i.e. x connected_to y and x proximal_to y. http://purl.obolibrary.org/obo/UBERON_0010531 metanephros induced blastemal cells http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure http://purl.obolibrary.org/obo/UBERON_0011757 differentiated genital tubercle http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure http://purl.obolibrary.org/obo/UBERON_0013238 future glans http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure http://purl.obolibrary.org/obo/uberon/core#posteriorly_connected_to posteriorly connected to http://purl.obolibrary.org/obo/RO_0002170 connected to x posteriorly_connected_to y iff the posterior part of x is connected to y. i.e. x connected_to y and x anterior_to y. http://purl.obolibrary.org/obo/UBERON_0014950 layer of developing cerebral cortex http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure http://purl.obolibrary.org/obo/uberon/core#proximally_connected_to proximally connected to http://purl.obolibrary.org/obo/RO_0002170 connected to x proximally_connected_to y iff the proximal part of x is connected to y. i.e. x connected_to y and x distal_to y. http://purl.obolibrary.org/obo/UBERON_0001889 trunk of phrenic nerve http://purl.obolibrary.org/obo/UBERON_0005476 spinal nerve trunk http://purl.obolibrary.org/obo/RO_0004007 has primary input or output http://purl.obolibrary.org/obo/RO_0000057 has participant p 'has primary input ot output' c iff either (a) p 'has primary input' c or (b) p 'has primary output' c. http://purl.obolibrary.org/obo/UBERON_0002327 trunk of intercostal nerve http://purl.obolibrary.org/obo/UBERON_0005476 spinal nerve trunk http://purl.obolibrary.org/obo/UBERON_0022247 forebrain ipsilateral fiber tracts http://purl.obolibrary.org/obo/UBERON_0005838 fasciculus of brain http://purl.obolibrary.org/obo/RO_0004008 has primary output http://purl.obolibrary.org/obo/RO_0004007 has primary input or output p has primary output c if (a) p has output c and (b) the goal of process is to modify, produce, or transform c. http://purl.obolibrary.org/obo/UBERON_0022248 cerebral nerve fasciculus http://purl.obolibrary.org/obo/UBERON_0005838 fasciculus of brain http://purl.obolibrary.org/obo/BFO_0000063 precedes http://purl.obolibrary.org/obo/RO_0002222 temporally related to x precedes y if and only if the time point at which x ends is before or equivalent to the time point at which y starts. Formally: x precedes y iff ω(x) <= α(y), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point. http://purl.obolibrary.org/obo/UBERON_0002792 lumbar spinal cord http://purl.obolibrary.org/obo/UBERON_0005844 spinal cord segment http://purl.obolibrary.org/obo/RO_0000052 characteristic of http://purl.obolibrary.org/obo/RO_0002314 characteristic of part of a relation between a specifically dependent continuant (the characteristic) and any other entity (the bearer), in which the characteristic depends on the bearer for its existence. http://purl.obolibrary.org/obo/UBERON_0005865 pre-muscle condensation http://purl.obolibrary.org/obo/UBERON_0005856 developing mesenchymal condensation http://purl.obolibrary.org/obo/UBERON_0006219 deltoid pre-muscle mass http://purl.obolibrary.org/obo/UBERON_0005865 pre-muscle condensation http://purl.obolibrary.org/obo/UBERON_0010955 trapezius pre-muscle mass http://purl.obolibrary.org/obo/UBERON_0010258 mesenchyme from rhombencephalic neural crest http://purl.obolibrary.org/obo/RO_0000080 quality of http://purl.obolibrary.org/obo/RO_0000052 characteristic of a relation between a quality and an independent continuant (the bearer), in which the quality specifically depends on the bearer for its existence http://purl.obolibrary.org/obo/UBERON_0010982 latissimus dorsi pre-muscle mass http://purl.obolibrary.org/obo/UBERON_0005865 pre-muscle condensation http://purl.obolibrary.org/obo/RO_0000086 has quality http://purl.obolibrary.org/obo/RO_0000053 has characteristic a relation between an independent continuant (the bearer) and a quality, in which the quality specifically depends on the bearer for its existence http://purl.obolibrary.org/obo/UBERON_0010983 levator scapulae pre-muscle mass http://purl.obolibrary.org/obo/UBERON_0005865 pre-muscle condensation http://purl.obolibrary.org/obo/RO_0002000 2D boundary of http://purl.obolibrary.org/obo/RO_0002323 mereotopologically related to a relation between a 2D immaterial entity (the boundary) and a material entity, in which the boundary delimits the material entity http://purl.obolibrary.org/obo/UBERON_0010984 pectoral pre-muscle mass http://purl.obolibrary.org/obo/UBERON_0005865 pre-muscle condensation http://purl.obolibrary.org/obo/RO_0002002 has 2D boundary http://purl.obolibrary.org/obo/RO_0002323 mereotopologically related to a relation between a material entity and a 2D immaterial entity (the boundary), in which the boundary delimits the material entity http://purl.obolibrary.org/obo/UBERON_0010986 serratus ventralis pre-muscle mass http://purl.obolibrary.org/obo/UBERON_0005865 pre-muscle condensation http://purl.obolibrary.org/obo/RO_0002219 surrounded by http://purl.obolibrary.org/obo/RO_0002220 adjacent to x surrounded_by y if and only if (1) x is adjacent to y and for every region r that is adjacent to x, r overlaps y (2) the shared boundary between x and y occupies the majority of the outermost boundary of x http://purl.obolibrary.org/obo/UBERON_0011332 extrinsic tongue pre-muscle mass http://purl.obolibrary.org/obo/UBERON_0005865 pre-muscle condensation http://purl.obolibrary.org/obo/UBERON_0010213 laryngeal pre-cartilage condensation http://purl.obolibrary.org/obo/UBERON_0005866 pre-cartilage condensation http://purl.obolibrary.org/obo/RO_0002220 adjacent to http://purl.obolibrary.org/obo/RO_0002163 spatially disjoint from x adjacent to y if and only if x and y share a boundary. http://purl.obolibrary.org/obo/UBERON_0010063 tympanic cavity epithelium http://purl.obolibrary.org/obo/UBERON_0015813 middle ear epithelium http://purl.obolibrary.org/obo/RO_0002223 starts http://purl.obolibrary.org/obo/BFO_0000050 part of inverse of starts with http://purl.obolibrary.org/obo/UBERON_0006106 cochlear canal http://purl.obolibrary.org/obo/UBERON_0005913 zone of bone organ http://purl.obolibrary.org/obo/RO_0002350 member of http://purl.obolibrary.org/obo/BFO_0000050 part of is member of is a mereological relation between a item and a collection. http://purl.obolibrary.org/obo/UBERON_0007172 angle of scapula http://purl.obolibrary.org/obo/UBERON_0005913 zone of bone organ http://purl.obolibrary.org/obo/RO_0002351 has member http://purl.obolibrary.org/obo/BFO_0000051 has part has member is a mereological relation between a collection and an item. http://purl.obolibrary.org/obo/UBERON_0019294 commissure of telencephalon http://purl.obolibrary.org/obo/UBERON_0005970 brain commissure http://purl.obolibrary.org/obo/RO_0002202 develops from http://purl.obolibrary.org/obo/RO_0002258 developmentally preceded by x develops from y if and only if either (a) x directly develops from y or (b) there exists some z such that x directly develops from z and z develops from y http://purl.obolibrary.org/obo/UBERON_0006136 unmyelinated nerve fiber http://purl.obolibrary.org/obo/UBERON_0006134 nerve fiber http://purl.obolibrary.org/obo/BFO_0000051 has part http://purl.obolibrary.org/obo/RO_0002131 overlaps a core relation that holds between a whole and its part http://purl.obolibrary.org/obo/UBERON_0002690 anteroventral periventricular nucleus http://purl.obolibrary.org/obo/UBERON_0006568 hypothalamic nucleus http://purl.obolibrary.org/obo/RO_0002176 connects http://purl.obolibrary.org/obo/RO_0002323 mereotopologically related to c connects a if and only if there exist some b such that a and b are similar parts of the same system, and c connects b, specifically, c connects a with b. When one structure connects two others it unites some aspect of the function or role they play within the system. http://purl.obolibrary.org/obo/UBERON_0002708 posterior periventricular nucleus http://purl.obolibrary.org/obo/UBERON_0006568 hypothalamic nucleus http://purl.obolibrary.org/obo/RO_0002491 existence starts and ends during http://purl.obolibrary.org/obo/RO_0002492 existence ends during x exists during y if and only if: 1) the time point at which x begins to exist is after or equal to the time point at which y begins and 2) the time point at which x ceases to exist is before or equal to the point at which y ends. Formally: x existence starts and ends during y iff α(x) >= α(y) & α(x) <= ω(y) & ω(x) <= ω(y) & ω(x) >= α(y) http://purl.obolibrary.org/obo/UBERON_0005795 embryonic uterus http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure http://purl.obolibrary.org/obo/RO_0002404 causally downstream of http://purl.obolibrary.org/obo/RO_0002427 causally downstream of or within inverse of upstream of http://purl.obolibrary.org/obo/UBERON_0006241 future spinal cord http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure http://purl.obolibrary.org/obo/RO_0002412 immediately causally upstream of http://purl.obolibrary.org/obo/RO_0002411 causally upstream of p is immediately causally upstream of q iff p is causally upstream of q, and the end of p is coincident with the beginning of q. http://purl.obolibrary.org/obo/UBERON_0006596 presumptive blood http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure http://purl.obolibrary.org/obo/RO_0002490 existence overlaps http://purl.obolibrary.org/obo/RO_0002487 relation between physical entity and a process or stage x existence overlaps y if and only if either (a) the start of x is part of y or (b) the end of x is part of y. Formally: x existence starts and ends during y iff (α(x) >= α(y) & α(x) <= ω(y)) OR (ω(x) <= ω(y) & ω(x) >= α(y)) http://purl.obolibrary.org/obo/UBERON_0006600 presumptive enteric nervous system http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure http://purl.obolibrary.org/obo/RO_0002252 connecting branch of http://purl.obolibrary.org/obo/RO_0002375 in branching relationship with b connecting-branch-of s iff b is connected to s, and there exists some tree-like structure t such that the mereological sum of b plus s is either the same as t or a branching-part-of t. http://purl.obolibrary.org/obo/UBERON_0007026 presumptive gut http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure http://purl.obolibrary.org/obo/RO_0002253 has connecting branch http://purl.obolibrary.org/obo/RO_0002375 in branching relationship with inverse of connecting branch of http://purl.obolibrary.org/obo/UBERON_0034875 future pituitary gland http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure http://purl.obolibrary.org/obo/RO_0002263 acts upstream of http://purl.obolibrary.org/obo/RO_0002264 acts upstream of or within c acts upstream of p if and only if c enables some f that is involved in p' and p' occurs chronologically before p, is not part of p, and affects the execution of p. c is a material entity and f, p, p' are processes. http://purl.obolibrary.org/obo/UBERON_0019310 glossopharyngeal nerve root http://purl.obolibrary.org/obo/UBERON_0006843 root of cranial nerve http://purl.obolibrary.org/obo/RO_0002304 causally upstream of, positive effect http://purl.obolibrary.org/obo/RO_0004047 causally upstream of or within, positive effect p is causally upstream of, positive effect q iff p is casually upstream of q, and the execution of p is required for the execution of q. http://purl.obolibrary.org/obo/UBERON_0006854 distal straight tubule postmacula segment http://purl.obolibrary.org/obo/UBERON_0006853 renal cortex tubule http://purl.obolibrary.org/obo/RO_0002305 causally upstream of, negative effect http://purl.obolibrary.org/obo/RO_0004046 causally upstream of or within, negative effect p is causally upstream of, negative effect q iff p is casually upstream of q, and the execution of p decreases the execution of q. http://purl.obolibrary.org/obo/UBERON_0009969 statoacoustic epithelium http://purl.obolibrary.org/obo/UBERON_0006934 sensory epithelium http://purl.obolibrary.org/obo/RO_0020337 has constituent monomer http://purl.obolibrary.org/obo/RO_0002180 has component A relation that holds between a polymer and its constituent monomers. P has_constituent_monomer 'm' if and only if P has_component multiple instances of 'm' and each instance of 'm' is covalently attached to another instance of 'm'. http://purl.obolibrary.org/obo/UBERON_0015128 subepicardial layer of epicardium http://purl.obolibrary.org/obo/UBERON_0007188 mesothelium of serous pericardium http://purl.obolibrary.org/obo/RO_0002131 overlaps http://purl.obolibrary.org/obo/RO_0002323 mereotopologically related to x overlaps y if and only if there exists some z such that x has part z and z part of y http://purl.obolibrary.org/obo/UBERON_0002615 ventral tegmental decussation http://purl.obolibrary.org/obo/UBERON_0007418 neural decussation http://purl.obolibrary.org/obo/RO_0002150 continuous with http://purl.obolibrary.org/obo/RO_0002323 mereotopologically related to X continuous_with Y if and only if X and Y share a fiat boundary. http://purl.obolibrary.org/obo/UBERON_0014706 primitive renal collecting duct system http://purl.obolibrary.org/obo/UBERON_0012275 meso-epithelium http://purl.obolibrary.org/obo/RO_0002254 has developmental contribution from http://purl.obolibrary.org/obo/RO_0002258 developmentally preceded by x has developmental contribution from y iff x has some part z such that z develops from y http://purl.obolibrary.org/obo/UBERON_0011921 connecting stalk blood islands http://purl.obolibrary.org/obo/UBERON_0012275 meso-epithelium http://purl.obolibrary.org/obo/RO_0002496 existence starts during or after http://purl.obolibrary.org/obo/RO_0002487 relation between physical entity and a process or stage x existence starts during or after y if and only if the time point at which x starts is after or equivalent to the time point at which y starts. Formally: x existence starts during or after y iff α (x) >= α (y). http://purl.obolibrary.org/obo/UBERON_0010221 laryngeal associated mesenchyme http://purl.obolibrary.org/obo/UBERON_0007524 dense mesenchyme tissue http://purl.obolibrary.org/obo/RO_0002497 existence ends during or before http://purl.obolibrary.org/obo/RO_0002487 relation between physical entity and a process or stage x existence ends during or before y if and only if the time point at which x ends is before or equivalent to the time point at which y ends. http://purl.obolibrary.org/obo/UBERON_0007606 ciliated stratified columnar epithelium http://purl.obolibrary.org/obo/UBERON_0007602 stratified columnar epithelium http://purl.obolibrary.org/obo/UBERON_0009632 root of cervical nerve http://purl.obolibrary.org/obo/UBERON_0009623 spinal nerve root http://purl.obolibrary.org/obo/RO_0012000 has small molecule regulator http://purl.obolibrary.org/obo/RO_0000057 has participant a relation between a process and a continuant, in which the process is regulated by the small molecule continuant http://purl.obolibrary.org/obo/UBERON_0002892 medial amygdaloid nucleus http://purl.obolibrary.org/obo/UBERON_0009663 telencephalic nucleus http://purl.obolibrary.org/obo/RO_0012001 has small molecule activator http://purl.obolibrary.org/obo/RO_0012000 has small molecule regulator a relation between a process and a continuant, in which the process is activated by the small molecule continuant http://purl.obolibrary.org/obo/UBERON_0002893 nucleus of lateral olfactory tract http://purl.obolibrary.org/obo/UBERON_0009663 telencephalic nucleus http://purl.obolibrary.org/obo/RO_0012003 acts on population of http://purl.obolibrary.org/obo/RO_0000057 has participant p acts on population of c iff c' is a collection, has members of type c, and p has participant c http://purl.obolibrary.org/obo/UBERON_0013150 future brain vesicle http://purl.obolibrary.org/obo/UBERON_0010000 multicellular anatomical structure http://purl.obolibrary.org/obo/RO_0012004 is small molecule regulator of http://purl.obolibrary.org/obo/RO_0002596 capable of regulating a relation between a continuant and a process, in which the continuant is a small molecule that regulates the process http://purl.obolibrary.org/obo/UBERON_0009638 orbitosphenoid ossification center http://purl.obolibrary.org/obo/UBERON_0010355 ossification center http://purl.obolibrary.org/obo/RO_0012005 is small molecule activator of http://purl.obolibrary.org/obo/RO_0002598 capable of positively regulating a relation between a continuant and a process, in which the continuant is a small molecule that activates the process http://purl.obolibrary.org/obo/UBERON_0010392 B cell domain http://purl.obolibrary.org/obo/UBERON_0010394 lymphocyte domain http://purl.obolibrary.org/obo/RO_0013001 has synaptic IO in region http://purl.obolibrary.org/obo/RO_0002130 has synaptic terminal in A relationship between a neuron and a region, where the neuron has a functionally relevant number of input and/or output synapses in that region. http://purl.obolibrary.org/obo/UBERON_0010393 T cell domain http://purl.obolibrary.org/obo/UBERON_0010394 lymphocyte domain http://purl.obolibrary.org/obo/BFO_0000062 preceded by http://purl.obolibrary.org/obo/RO_0002086 ends after x is preceded by y if and only if the time point at which y ends is before or equivalent to the time point at which x starts. Formally: x preceded by y iff ω(y) <= α(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point. http://purl.obolibrary.org/obo/UBERON_0010528 pneumatic cavity of bone http://purl.obolibrary.org/obo/UBERON_0010527 cavity of bone organ http://purl.obolibrary.org/obo/RO_0002090 immediately precedes http://purl.obolibrary.org/obo/BFO_0000063 precedes http://purl.obolibrary.org/obo/UBERON_0010700 phalanx pre-cartilage condensation http://purl.obolibrary.org/obo/UBERON_0015023 phalanx endochondral element http://purl.obolibrary.org/obo/GOREL_0002004 results_in_fission_of http://purl.obolibrary.org/obo/RO_0000057 has participant http://purl.obolibrary.org/obo/UBERON_0010698 manual digit metacarpus pre-cartilage condensation http://purl.obolibrary.org/obo/UBERON_0015042 manual digit metacarpus endochondral element http://purl.obolibrary.org/obo/RO_0002087 immediately preceded by http://purl.obolibrary.org/obo/BFO_0000062 preceded by http://purl.obolibrary.org/obo/UBERON_0013605 layer of lateral geniculate body http://purl.obolibrary.org/obo/UBERON_0022303 nervous system cell part layer http://purl.obolibrary.org/obo/RO_0002081 before or simultaneous with http://purl.obolibrary.org/obo/RO_0002222 temporally related to http://purl.obolibrary.org/obo/UBERON_0014530 white matter lamina of neuraxis http://purl.obolibrary.org/obo/UBERON_0022303 nervous system cell part layer http://purl.obolibrary.org/obo/RO_0002086 ends after http://purl.obolibrary.org/obo/RO_0002222 temporally related to http://purl.obolibrary.org/obo/UBERON_0016550 spinal cord column http://purl.obolibrary.org/obo/UBERON_0011215 central nervous system cell part cluster http://purl.obolibrary.org/obo/uberon/core#layer_part_of layer part of http://purl.obolibrary.org/obo/BFO_0000050 part of http://purl.obolibrary.org/obo/UBERON_0016570 lamina of gray matter of spinal cord http://purl.obolibrary.org/obo/UBERON_0022303 nervous system cell part layer http://purl.obolibrary.org/obo/UBERON_0022320 dorsal cochlear nucleus pyramidal cell layer http://purl.obolibrary.org/obo/UBERON_0022303 nervous system cell part layer http://purl.obolibrary.org/obo/uberon/core#trunk_part_of trunk_part_of http://purl.obolibrary.org/obo/BFO_0000050 part of http://purl.obolibrary.org/obo/UBERON_0006525 left lung alveolar system http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision http://purl.obolibrary.org/obo/uberon/core#filtered_through filtered through Relationship between a fluid and a material entity, where the fluid is the output of a realization of a filtration role that inheres in the material entity. http://purl.obolibrary.org/obo/UBERON_0006526 right lung alveolar system http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision http://purl.obolibrary.org/obo/RO_0002320 evolutionarily related to A relationship that holds via some environmental process http://purl.obolibrary.org/obo/UBERON_0010191 aortic system http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision http://purl.obolibrary.org/obo/RO_0002324 developmentally related to A relationship that holds between entities participating in some developmental process (GO:0032502) http://purl.obolibrary.org/obo/UBERON_0001606 muscle of iris http://purl.obolibrary.org/obo/UBERON_0011222 intra-ocular muscle http://purl.obolibrary.org/obo/uberon/core#indirectly_supplies indirectly_supplies a indirectly_supplies s iff a has a branch and the branch supplies or indirectly supplies s. http://purl.obolibrary.org/obo/UBERON_0025261 thalamic fiber tract http://purl.obolibrary.org/obo/UBERON_0011591 tract of diencephalon http://purl.obolibrary.org/obo/uberon/core#site_of site_of c site_of p if c is the bearer of a disposition that is realized by a process that has p as part. http://purl.obolibrary.org/obo/UBERON_0005434 cervical region http://purl.obolibrary.org/obo/UBERON_0011676 subdivision of organism along main body axis http://purl.obolibrary.org/obo/RO_0015004 has characterizing marker set A relation that applies between a cell type and a set of markers that can be used to uniquely identify that cell type. http://purl.obolibrary.org/obo/UBERON_0011696 left extraembryonic umbilical artery http://purl.obolibrary.org/obo/UBERON_0011693 extraembryonic portion of umbilical artery http://purl.obolibrary.org/obo/BFO_0000067 contains process [copied from inverse property 'occurs in'] b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t http://purl.obolibrary.org/obo/UBERON_0011697 right extraembryonic umbilical artery http://purl.obolibrary.org/obo/UBERON_0011693 extraembryonic portion of umbilical artery http://purl.obolibrary.org/obo/RO_0000053 has characteristic Inverse of characteristic_of http://purl.obolibrary.org/obo/UBERON_0011824 fibrous connective tissue http://purl.obolibrary.org/obo/UBERON_0011822 dense irregular connective tissue http://purl.obolibrary.org/obo/RO_0000056 participates in a relation between a continuant and a process, in which the continuant is somehow involved in the process http://purl.obolibrary.org/obo/UBERON_0018135 fibrocollagenous connective tissue http://purl.obolibrary.org/obo/UBERON_0011824 fibrous connective tissue http://purl.obolibrary.org/obo/RO_0000057 has participant a relation between a process and a continuant, in which the continuant is somehow involved in the process http://purl.obolibrary.org/obo/UBERON_0009292 embryonic nasal process http://purl.obolibrary.org/obo/UBERON_0012314 embryonic facial prominence http://purl.obolibrary.org/obo/RO_0001000 derives from a relation between two distinct material entities, the new entity and the old entity, in which the new entity begins to exist when the old entity ceases to exist, and the new entity inherits the significant portion of the matter of the old entity http://purl.obolibrary.org/obo/UBERON_0012485 cloacal villus http://purl.obolibrary.org/obo/UBERON_0012423 layer of microvilli http://purl.obolibrary.org/obo/RO_0001001 derives into a relation between two distinct material entities, the old entity and the new entity, in which the new entity begins to exist when the old entity ceases to exist, and the new entity inherits the significant portion of the matter of the old entity http://purl.obolibrary.org/obo/UBERON_0009676 early telencephalic vesicle http://purl.obolibrary.org/obo/UBERON_0013150 future brain vesicle http://purl.obolibrary.org/obo/RO_0001015 location of a relation between two independent continuants, the location and the target, in which the target is entirely within the location http://purl.obolibrary.org/obo/UBERON_0013149 hindbrain vesicle http://purl.obolibrary.org/obo/UBERON_0013150 future brain vesicle http://purl.obolibrary.org/obo/RO_0017001 device utilizes material X device utilizes material Y means X and Y are material entities, and X is capable of some process P that has input Y. http://purl.obolibrary.org/obo/UBERON_0013606 magnocellular layer of dorsal nucleus of lateral geniculate body http://purl.obolibrary.org/obo/UBERON_0013605 layer of lateral geniculate body http://purl.obolibrary.org/obo/RO_0001025 located in a relation between two independent continuants, the target and the location, in which the target is entirely within the location http://purl.obolibrary.org/obo/UBERON_0013607 parvocellular layer of dorsal nucleus of lateral geniculate body http://purl.obolibrary.org/obo/UBERON_0013605 layer of lateral geniculate body http://purl.obolibrary.org/obo/RO_0003000 produces a produces b if some process that occurs_in a has_output b, where a and b are material entities. Examples: hybridoma cell line produces monoclonal antibody reagent; chondroblast produces avascular GAG-rich matrix. http://purl.obolibrary.org/obo/UBERON_0013615 koniocellular layer of dorsal nucleus of lateral geniculate body http://purl.obolibrary.org/obo/UBERON_0013605 layer of lateral geniculate body http://purl.obolibrary.org/obo/RO_0003001 produced by a produced_by b iff some process that occurs_in b has_output a. http://purl.obolibrary.org/obo/UBERON_0014531 white matter lamina of diencephalon http://purl.obolibrary.org/obo/UBERON_0014530 white matter lamina of neuraxis http://purl.obolibrary.org/obo/RO_0015001 has exemplar data A relation between a material entity and some data in which the data is taken as exemplifying the material entity. http://purl.obolibrary.org/obo/UBERON_0014532 white matter lamina of cerebral hemisphere http://purl.obolibrary.org/obo/UBERON_0014530 white matter lamina of neuraxis http://purl.obolibrary.org/obo/STATO_0000101 has numerator the relationship between a fraction and the number above the line http://purl.obolibrary.org/obo/UBERON_0019292 white matter of pons http://purl.obolibrary.org/obo/UBERON_0019291 white matter of metencephalon http://purl.obolibrary.org/obo/STATO_0000259 has denominator the relationship between a fraction and the number below the line (or divisor) http://purl.obolibrary.org/obo/UBERON_0010701 phalanx cartilage element http://purl.obolibrary.org/obo/UBERON_0015064 autopod cartilage http://purl.obolibrary.org/obo/uberon/core#channels_from channels_from http://purl.obolibrary.org/obo/UBERON_0010697 pedal digit metatarsal cartilage element http://purl.obolibrary.org/obo/UBERON_0035129 pes cartilage element http://purl.obolibrary.org/obo/uberon/core#channels_into channels_into http://purl.obolibrary.org/obo/UBERON_0010699 manual digit metacarpus cartilage element http://purl.obolibrary.org/obo/UBERON_0035128 manus cartilage element http://purl.obolibrary.org/obo/uberon/core#transitively_anteriorly_connected_to transitively anteriorly connected to http://purl.obolibrary.org/obo/UBERON_0003030 posterior nucleus of thalamus http://purl.obolibrary.org/obo/UBERON_0015233 nucleus of dorsal thalamus http://purl.obolibrary.org/obo/uberon/core#transitively_distally_connected_to transitively distally connected to http://purl.obolibrary.org/obo/UBERON_0005275 dorsal skin of digit http://purl.obolibrary.org/obo/UBERON_0015249 digit skin http://purl.obolibrary.org/obo/uberon/core#transitively_proximally_connected_to transitively proximally connected to http://purl.obolibrary.org/obo/UBERON_0034769 lymphomyeloid tissue http://purl.obolibrary.org/obo/UBERON_0015757 heterogeneous tissue http://purl.obolibrary.org/obo/RO_0002487 relation between physical entity and a process or stage http://purl.obolibrary.org/obo/UBERON_0022279 strand of hair on external ear http://purl.obolibrary.org/obo/UBERON_0016446 hair of head http://purl.obolibrary.org/obo/CL_4030045 lacks_part http://purl.obolibrary.org/obo/UBERON_0016542 limbic cortex http://purl.obolibrary.org/obo/UBERON_0016529 cortex of cerebral lobe http://purl.obolibrary.org/obo/RO_0002411 causally upstream of http://purl.obolibrary.org/obo/RO_0002418 causally upstream of or within p is causally upstream of q iff p is causally related to q, the end of p precedes the end of q, and p is not an occurrent part of q. http://purl.obolibrary.org/obo/UBERON_0018667 neck of scapula http://purl.obolibrary.org/obo/UBERON_0018664 neck of bone element http://purl.obolibrary.org/obo/BFO_0000050 part of http://purl.obolibrary.org/obo/RO_0002131 overlaps a core relation that holds between a part and its whole http://purl.obolibrary.org/obo/UBERON_0019291 white matter of metencephalon http://purl.obolibrary.org/obo/UBERON_0019258 white matter of hindbrain http://purl.obolibrary.org/obo/RO_0002211 regulates http://purl.obolibrary.org/obo/RO_0002411 causally upstream of p regulates q iff p is causally upstream of q, the execution of p is not constant and varies according to specific conditions, and p influences the rate or magnitude of execution of q due to an effect either on some enabler of q or some enabler of a part of q. http://purl.obolibrary.org/obo/UBERON_0019269 gray matter of diencephalon http://purl.obolibrary.org/obo/UBERON_0019264 gray matter of forebrain http://purl.obolibrary.org/obo/RO_0002212 negatively regulates http://purl.obolibrary.org/obo/RO_0002211 regulates p negatively regulates q iff p regulates q, and p decreases the rate or magnitude of execution of q. http://purl.obolibrary.org/obo/UBERON_0019293 white matter of pontine tegmentum http://purl.obolibrary.org/obo/UBERON_0019292 white matter of pons http://purl.obolibrary.org/obo/RO_0002213 positively regulates http://purl.obolibrary.org/obo/RO_0002211 regulates p positively regulates q iff p regulates q, and p increases the rate or magnitude of execution of q. http://purl.obolibrary.org/obo/UBERON_0019306 nose epithelium http://purl.obolibrary.org/obo/UBERON_0019304 sensory organ epithelium http://purl.obolibrary.org/obo/RO_0002180 has component http://purl.obolibrary.org/obo/BFO_0000051 has part w 'has component' p if w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type. http://purl.obolibrary.org/obo/UBERON_0022236 peduncle of thalamus http://purl.obolibrary.org/obo/UBERON_0022235 peduncle of diencephalon http://purl.obolibrary.org/obo/RO_0002163 spatially disjoint from http://purl.obolibrary.org/obo/RO_0002323 mereotopologically related to A is spatially_disjoint_from B if and only if they have no parts in common http://purl.obolibrary.org/obo/UBERON_0025736 chemoarchitectural part of striatum http://purl.obolibrary.org/obo/UBERON_0024090 chemoarchitectural part of brain http://purl.obolibrary.org/obo/RO_0002233 has input http://purl.obolibrary.org/obo/RO_0000057 has participant p has input c iff: p is a process, c is a material entity, c is a participant in p, c is present at the start of p, and the state of c is modified during p. http://purl.obolibrary.org/obo/UBERON_0029002 matrix compartment of putamen http://purl.obolibrary.org/obo/UBERON_0027368 matrix compartment http://purl.obolibrary.org/obo/RO_0002314 characteristic of part of http://purl.obolibrary.org/obo/RO_0002502 depends on q characteristic of part of w if and only if there exists some p such that q inheres in p and p part of w. http://purl.obolibrary.org/obo/UBERON_0029004 striosomal part of caudate nucleus http://purl.obolibrary.org/obo/UBERON_0027371 striosome http://purl.obolibrary.org/obo/RO_0002352 input of http://purl.obolibrary.org/obo/RO_0002328 functionally related to inverse of has input http://purl.obolibrary.org/obo/UBERON_0029005 striosomal part of putamen http://purl.obolibrary.org/obo/UBERON_0027371 striosome http://purl.obolibrary.org/obo/RO_0002353 output of http://purl.obolibrary.org/obo/RO_0002328 functionally related to inverse of has output http://purl.obolibrary.org/obo/UBERON_0034708 cerebellum marginal layer http://purl.obolibrary.org/obo/UBERON_0034709 hindbrain marginal layer http://purl.obolibrary.org/obo/RO_0002473 composed primarily of http://purl.obolibrary.org/obo/BFO_0000051 has part x composed_primarily_of y if and only if more than half of the mass of x is made from y or units of the same type as y. http://purl.obolibrary.org/obo/UBERON_0003110 otic region http://purl.obolibrary.org/obo/UBERON_0034921 multi organ part structure http://purl.obolibrary.org/obo/RO_0002104 has plasma membrane part http://purl.obolibrary.org/obo/BFO_0000051 has part Holds between a cell c and a protein complex or protein p if and only if that cell has as part a plasma_membrane[GO:0005886], and that plasma membrane has p as part. http://purl.obolibrary.org/obo/UBERON_0018691 ventral side of post-anal tail http://purl.obolibrary.org/obo/UBERON_0034929 external soft tissue zone http://purl.obolibrary.org/obo/RO_0002203 develops into http://purl.obolibrary.org/obo/RO_0002387 has potential to develop into inverse of develops from http://purl.obolibrary.org/obo/UBERON_0018692 dorsal side of post-anal tail http://purl.obolibrary.org/obo/UBERON_0034929 external soft tissue zone http://purl.obolibrary.org/obo/RO_0002215 capable of http://purl.obolibrary.org/obo/RO_0002216 capable of part of A relation between a material entity (such as a cell) and a process, in which the material entity has the ability to carry out the process. http://purl.obolibrary.org/obo/CLM_5022204 Alk,Atp13a4 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/RO_0002387 has potential to develop into http://purl.obolibrary.org/obo/RO_0002384 has developmental potential involving x has the potential to develop into y iff x develops into y or if x is capable of developing into y http://purl.obolibrary.org/obo/NCBITaxon_337687 Muroidea http://purl.obolibrary.org/obo/NCBITaxon_1963758 Myomorpha http://purl.obolibrary.org/obo/RO_0002021 occurs across http://purl.obolibrary.org/obo/RO_0002479 has part that occurs in A relationship between a process and a barrier, where the process occurs in a region spanning the barrier. For cellular processes the barrier is typically a membrane. Examples include transport across a membrane and membrane depolarization. http://purl.obolibrary.org/obo/UBERON_0006056 posterior surface of head http://purl.obolibrary.org/obo/UBERON_0036215 anatomical surface region http://purl.obolibrary.org/obo/RO_0015007 increased in magnitude relative to http://purl.obolibrary.org/obo/RO_0015006 different in magnitude relative to q1 increased_in_magnitude_relative_to q2 if and only if magnitude(q1) > magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale. http://purl.obolibrary.org/obo/UBERON_0017659 ventral surface of penis http://purl.obolibrary.org/obo/UBERON_0036215 anatomical surface region http://purl.obolibrary.org/obo/RO_0015008 decreased in magnitude relative to http://purl.obolibrary.org/obo/RO_0015006 different in magnitude relative to q1 decreased_in_magnitude_relative_to q2 if and only if magnitude(q1) < magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale. http://purl.obolibrary.org/obo/UBERON_0022288 surface of eyeball http://purl.obolibrary.org/obo/UBERON_0036215 anatomical surface region http://purl.obolibrary.org/obo/RO_0002007 bounding layer of http://purl.obolibrary.org/obo/BFO_0000050 part of X outer_layer_of Y iff: . X :continuant that bearer_of some PATO:laminar . X part_of Y . exists Z :surface . X has_boundary Z . Z boundary_of Y has_boundary: http://purl.obolibrary.org/obo/RO_0002002 boundary_of: http://purl.obolibrary.org/obo/RO_0002000 http://purl.obolibrary.org/obo/UBERON_0034928 dorsal surface of penis http://purl.obolibrary.org/obo/UBERON_0036215 anatomical surface region http://purl.obolibrary.org/obo/RO_0002170 connected to http://purl.obolibrary.org/obo/RO_0002323 mereotopologically related to a is connected to b if and only if a and b are discrete structure, and there exists some connecting structure c, such that c connects a and b http://purl.obolibrary.org/obo/UBERON_0007171 border of scapula http://purl.obolibrary.org/obo/UBERON_0036304 anatomical border http://purl.obolibrary.org/obo/RO_0002177 attached to part of http://purl.obolibrary.org/obo/RO_0002567 biomechanically related to a is attached to part of b if a is attached to b, or a is attached to some p, where p is part of b. http://purl.obolibrary.org/obo/NCBITaxon_4894 Schizosaccharomycetaceae http://purl.obolibrary.org/obo/NCBITaxon_34346 Schizosaccharomycetales http://purl.obolibrary.org/obo/RO_0002179 drains http://purl.obolibrary.org/obo/RO_0002170 connected to Relation between an collecting structure and another structure, where the collecting structure acts as a conduit channeling fluid, substance or energy away from the other structure. http://purl.obolibrary.org/obo/NCBITaxon_1206795 Lophotrochozoa http://purl.obolibrary.org/obo/NCBITaxon_2697495 Spiralia http://purl.obolibrary.org/obo/RO_0002264 acts upstream of or within http://purl.obolibrary.org/obo/RO_0002500 causal agent in process c acts upstream of or within p if c is enables f, and f is causally upstream of or within p. c is a material entity and p is an process. http://purl.obolibrary.org/obo/UBERON_0001560 neck of organ http://purl.obolibrary.org/obo/UBERON_0034944 zone of organ http://purl.obolibrary.org/obo/RO_0002375 in branching relationship with http://purl.obolibrary.org/obo/RO_0002323 mereotopologically related to A relationship that holds between two material entities in a system of connected structures, where the branching relationship holds based on properties of the connecting network. http://purl.obolibrary.org/obo/UBERON_0005913 zone of bone organ http://purl.obolibrary.org/obo/UBERON_0034944 zone of organ http://purl.obolibrary.org/obo/RO_0002376 tributary of http://purl.obolibrary.org/obo/RO_0002375 in branching relationship with x tributary_of y if and only if x a channel for the flow of a substance into y, where y is larger than x. If x and y are hydrographic features, then y is the main stem of a river, or a lake or bay, but not the sea or ocean. If x and y are anatomical, then y is a vein. http://purl.obolibrary.org/obo/NCBITaxon_9480 Callitrichinae http://purl.obolibrary.org/obo/NCBITaxon_9498 Cebidae http://purl.obolibrary.org/obo/RO_0002431 involved in or involved in regulation of http://purl.obolibrary.org/obo/RO_0002500 causal agent in process c involved in or regulates p if and only if either (i) c is involved in p or (ii) c is involved in regulation of p http://purl.obolibrary.org/obo/CL_4023098 obsolete L2/3 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (Homo sapiens) OBSOLETE An intratelencephalic-projecting glutamatergic neuron with a soma found in layer 2/3 of the human primary motor cortex. http://purl.obolibrary.org/obo/RO_0002567 biomechanically related to http://purl.obolibrary.org/obo/RO_0002328 functionally related to A relation that holds between elements of a musculoskeletal system or its analogs. http://purl.obolibrary.org/obo/PR_000064867 protein-containing molecular entity A molecular entity that minimally consists of a protein. http://purl.obolibrary.org/obo/RO_0002373 has muscle insertion http://purl.obolibrary.org/obo/RO_0002567 biomechanically related to m has_muscle_insertion s iff m is attaches_to s, and it is the case that when m contracts, s moves. Insertions are usually connections of muscle via tendon to bone. http://purl.obolibrary.org/obo/CL_0017505 obsolete increased nucleus size OBSOLETE. A nucleus size quality which is relatively high compared to the amount of cytoplasm present in the same cell. http://purl.obolibrary.org/obo/PATO_0000001 quality A dependent entity that inheres in a bearer by virtue of how the bearer is related to other entities http://purl.obolibrary.org/obo/RO_0002433 contributes to morphology of http://purl.obolibrary.org/obo/RO_0002131 overlaps p contributes to morphology of w if and only if a change in the morphology of p entails a change in the morphology of w. Examples: every skull contributes to morphology of the head which it is a part of. Counter-example: nuclei do not generally contribute to the morphology of the cell they are part of, as they are buffered by cytoplasm. http://purl.obolibrary.org/obo/CL_4023078 obsolete basket morphology L2/3 pvalb-like sst GABAergic cortical interneuron (Mus musculus) OBSOLETE A L2/3 pvalb-like sst GABAergic cortical interneuron (Mus musculus) that has basket morphology. http://purl.obolibrary.org/obo/CL_0000003 obsolete native cell OBSOLETE. A cell that is found in a natural setting, which includes multicellular organism cells 'in vivo' (i.e. part of an organism), and unicellular organisms 'in environment' (i.e. part of a natural environment). http://purl.obolibrary.org/obo/RO_0002488 existence starts during http://purl.obolibrary.org/obo/RO_0002496 existence starts during or after x existence starts during y if and only if the time point at which x starts is after or equivalent to the time point at which y starts and before or equivalent to the time point at which y ends. Formally: x existence starts during y iff α(x) >= α(y) & α(x) <= ω(y). http://purl.obolibrary.org/obo/CL_0000055 obsolete non-terminally differentiated cell OBSOLETE. A precursor cell with a limited number of potential fates. http://purl.obolibrary.org/obo/RO_0002489 existence starts with http://purl.obolibrary.org/obo/RO_0002488 existence starts during x starts ends with y if and only if the time point at which x starts is equivalent to the time point at which y starts. Formally: x existence starts with y iff α(x) = α(y). http://purl.obolibrary.org/obo/CL_0000111 obsolete peripheral neuron OBSOLETE A neuron that is part of nerve found outside the central nervous system. http://purl.obolibrary.org/obo/RO_0002492 existence ends during http://purl.obolibrary.org/obo/RO_0002497 existence ends during or before x existence ends during y if and only if the time point at which x ends is before or equivalent to the time point at which y ends and after or equivalent to the point at which y starts. Formally: x existence ends during y iff ω(x) <= ω(y) and ω(x) >= α(y). http://purl.obolibrary.org/obo/CL_0000181 obsolete metabolising cell A cell whose primary function is intermediary metabolism. http://purl.obolibrary.org/obo/CL_0000212 obsolete absorptive cell OBSOLETE. A cell that takes up and metabolizes substances. http://purl.obolibrary.org/obo/RO_0002493 existence ends with http://purl.obolibrary.org/obo/RO_0002492 existence ends during x existence ends with y if and only if the time point at which x ends is equivalent to the time point at which y ends. Formally: x existence ends with y iff ω(x) = ω(y). http://purl.obolibrary.org/obo/CL_0000213 obsolete lining cell OBSOLETE. A cell within an epithelial cell sheet whose main function is to act as an internal or external covering for a tissue or an organism. http://purl.obolibrary.org/obo/RO_0002494 transformation of http://purl.obolibrary.org/obo/RO_0002202 develops from x transformation of y if x is the immediate transformation of y, or is linked to y through a chain of transformation relationships http://purl.obolibrary.org/obo/CL_0000215 obsolete barrier cell OBSOLETE. A cell whose primary function is to prevent the transport of stuff across compartments. http://purl.obolibrary.org/obo/RO_0002495 immediate transformation of http://purl.obolibrary.org/obo/RO_0002207 directly develops from x immediate transformation of y iff x immediately succeeds y temporally at a time boundary t, and all of the matter present in x at t is present in y at t, and all the matter in y at t is present in x at t http://purl.obolibrary.org/obo/CL_0000243 obsolete glial cell (sensu Vertebrata) A non-neuronal cell of the nervous system. They not only provide physical support, but also respond to injury, regulate the ionic and chemical composition of the extracellular milieu. Form the myelin insulation of nervous pathways, guide neuronal migration during development, and exchange metabolites with neurons. Neuroglia have high-affinity transmitter uptake systems, voltage-dependent and transmitter-gated ion channels, and can release transmitters, but their role in signaling (as in many other functions) is unclear. http://purl.obolibrary.org/obo/RO_0002551 has skeleton http://purl.obolibrary.org/obo/BFO_0000051 has part A relation between a segment or subdivision of an organism and the maximal subdivision of material entities that provides structural support for that segment or subdivision. http://purl.obolibrary.org/obo/CL_0000293 obsolete structural cell OBSOLETE. A cell whose primary function is to provide structural support, to provide strength and physical integrity to the organism. http://purl.obolibrary.org/obo/RO_0002572 luminal space of http://purl.obolibrary.org/obo/RO_0002571 lumen of s is luminal space of x iff s is lumen_of x and s is an immaterial entity http://purl.obolibrary.org/obo/CL_0000402 obsolete CNS interneuron OBSOLETE. An interneuron that has its cell body in a central nervous system. http://purl.obolibrary.org/obo/RO_0002576 skeleton of http://purl.obolibrary.org/obo/BFO_0000050 part of inverse of has skeleton http://purl.obolibrary.org/obo/CL_0000473 OBSOLETE defensive cell OBSOLETE: A cell whose primary function is to protect the organism. http://purl.obolibrary.org/obo/uberon/core#extends_fibers_into extends_fibers_into http://purl.obolibrary.org/obo/RO_0002170 connected to X extends_fibers into Y iff there exists some neuron (N) and N has_soma_location X and N 'has synaptic IO in region' some Y http://purl.obolibrary.org/obo/CL_0000548 obsolete animal cell OBSOLETE. A native cell that is part of some Metazoa. http://purl.obolibrary.org/obo/RO_0020101 vessel supplies blood to http://purl.obolibrary.org/obo/RO_0002178 supplies x vessel supplies blood to y if and only if x is a vessel that supplies blood directly or indirectly to an anatomical structure y. http://purl.obolibrary.org/obo/CL_0000627 obsolete transporting cell OBSOLETE. A cell involved in transporting nutrients, minerals, water, gases and other chemicals between cells for a variety of purposes including conveying nutrition to other tissues, removing waste products from the tissues, conveying gases for respiration, distributing heat and repelling invasion of foreign substances. http://purl.obolibrary.org/obo/RO_0020102 vessel drains blood from http://purl.obolibrary.org/obo/RO_0002179 drains x vessel drains blood from y if and only if x is a vessel that drains blood directly or indirectly from an anatomical structure y. http://purl.obolibrary.org/obo/CL_0000651 obsolete mucous neck cell OBSOLETE. A mucus-secreting cell, with numerous apical secretory vesicles containing mucins; nucleus are basally displaced; numerous at the neck of mucus secreting glands http://purl.obolibrary.org/obo/RO_0002101 fasciculates with http://purl.obolibrary.org/obo/RO_0002131 overlaps relationship between a neuron and a neuron projection bundle (e.g.- tract or nerve bundle) that one or more of its projections travels through. http://purl.obolibrary.org/obo/CL_0000717 obsolete fusimotor neuron OBSOLETE. A subset of motor neurons that innervates intrafusal muscle fibers and has small diameter axons. http://purl.obolibrary.org/obo/RO_0002103 synapsed by http://purl.obolibrary.org/obo/RO_0002485 receives input from Relation between an anatomical structure (including cells) and a neuron that chemically synapses to it. http://purl.obolibrary.org/obo/CL_0002182 obsolete surface mucosal cell of stomach OBSOLETE. A simple columnar cell that populates the entire luminal surface including the gastric pits. This cell types secrete mucus to form a thick protective, lubricant layer over the gastric wall. http://purl.obolibrary.org/obo/RO_0002110 has postsynaptic terminal in http://purl.obolibrary.org/obo/RO_0002130 has synaptic terminal in Relation between a neuron and some structure (e.g.- a brain region) in which it receives (chemical) synaptic input. http://purl.obolibrary.org/obo/CL_0002371 obsolete somatic cell OBSOLETE. A cell of an organism that does not pass on its genetic material to the organism's offspring (i.e. a non-germ line cell). http://purl.obolibrary.org/obo/RO_0002113 has presynaptic terminal in http://purl.obolibrary.org/obo/RO_0002130 has synaptic terminal in Relation between a neuron and some structure (e.g.- a brain region) in which it receives (chemical) synaptic input. http://purl.obolibrary.org/obo/CL_0002609 obsolete neuron of cerebral cortex OBSOLETE. A CNS neuron of the cerebral cortex. http://purl.obolibrary.org/obo/RO_0002120 synapsed to http://purl.obolibrary.org/obo/RO_0002486 sends output to Relation between a neuron and an anatomical structure (including cells) that it chemically synapses to. http://purl.obolibrary.org/obo/CL_0002646 obsolete epithelial cell of buccal part of viscerocranial mucosa An ecto-epithelial cell of the buccal region of the viscerocranial mucosa. http://purl.obolibrary.org/obo/RO_0002130 has synaptic terminal in http://purl.obolibrary.org/obo/RO_0002131 overlaps A general relation between a neuron and some structure in which it either chemically synapses to some target or in which it receives (chemical) synaptic input. http://purl.obolibrary.org/obo/CL_0002647 obsolete epithelial cell of anterior palatal part of viscerocranial mucosa An ecto-epithelial cell of the palatal region of the viscerocranial mucosa. http://purl.obolibrary.org/obo/RO_0002216 capable of part of http://purl.obolibrary.org/obo/RO_0002500 causal agent in process c stands in this relationship to p if and only if there exists some p' such that c is capable_of p', and p' is part_of p. http://purl.obolibrary.org/obo/CL_0002648 obsolete epithelial cell of nasal part of viscerocranial mucosa An ecto-epithelial cell of the nasal region of the viscerocranial mucosa. http://purl.obolibrary.org/obo/RO_0002255 developmentally contributes to http://purl.obolibrary.org/obo/RO_0002385 has potential to developmentally contribute to inverse of has developmental contribution from http://purl.obolibrary.org/obo/CL_0002649 obsolete epithelial cell of gingival part of viscerocranial mucosa An ecto-epithelial cell of the gingival region of the viscerocranial mucosa. http://purl.obolibrary.org/obo/RO_0002329 part of structure that is capable of http://purl.obolibrary.org/obo/RO_0002328 functionally related to this relation holds between c and p when c is part of some c', and c' is capable of p. http://purl.obolibrary.org/obo/CL_0002650 obsolete epithelial cell of paranasal sinus part of viscerocranial mucosa An ecto-epithelial cell of the paranasal region of the viscerocranial mucosa. http://purl.obolibrary.org/obo/RO_0002334 regulated by http://purl.obolibrary.org/obo/RO_0002427 causally downstream of or within inverse of regulates http://purl.obolibrary.org/obo/CL_0008014 obsolete excitatory motor neuron A motor neuron that is capable of directly inducing muscle contraction. http://purl.obolibrary.org/obo/RO_0002335 negatively regulated by http://purl.obolibrary.org/obo/RO_0002334 regulated by inverse of negatively regulates http://purl.obolibrary.org/obo/CL_0010003 obsolete epithelial cell of alveolus of lung OBSOLETE. An epithelial cell that is part_of a alveolus of lung. http://purl.obolibrary.org/obo/RO_0002336 positively regulated by http://purl.obolibrary.org/obo/RO_0002334 regulated by inverse of positively regulates http://purl.obolibrary.org/obo/CL_0011107 obsolete Muller cell OBSOLETE: Astrocyte-like radial glial cell that extends vertically throughout the retina, with the nucleus are usually in the middle of the inner nuclear layer. http://purl.obolibrary.org/obo/RO_0002379 spatially coextensive with http://purl.obolibrary.org/obo/RO_0002131 overlaps x spatially_coextensive_with y if and inly if x and y have the same location http://purl.obolibrary.org/obo/CL_0011112 obsolete magnocellular neurosecretory cell OBSOLETE: Neurons part of the hypothalamic supraoptic and paraventricular nuclei that secrete the hormones, oxytocin and vasopressin into the systemic circulation from the posterior pituitary gland. http://purl.obolibrary.org/obo/RO_0002385 has potential to developmentally contribute to http://purl.obolibrary.org/obo/RO_0002384 has developmental potential involving x has potential to developmentrally contribute to y iff x developmentally contributes to y or x is capable of developmentally contributing to y http://purl.obolibrary.org/obo/CL_1000416 obsolete myoepithelial cell of lactiferous gland OBSOLETE. A myoepithelial cell that is part of the mammary gland. http://purl.obolibrary.org/obo/RO_0002418 causally upstream of or within http://purl.obolibrary.org/obo/RO_0002501 causal relation between processes p is 'causally upstream or within' q iff p is causally related to q, and the end of p precedes, or is coincident with, the end of q. http://purl.obolibrary.org/obo/CL_1001566 obsolete bronchioalveolar stem cells OBSOLETE. A respiratory stem cell found at the junction of the terminal (conductive) bronchiole and the respiratory bronchiole, which gives rise to alveolar cell types and club cells in response to lung injury. http://purl.obolibrary.org/obo/RO_0002427 causally downstream of or within http://purl.obolibrary.org/obo/RO_0002501 causal relation between processes inverse of causally upstream of or within http://purl.obolibrary.org/obo/RO_0002500 causal agent in process http://purl.obolibrary.org/obo/RO_0002595 causal relation between material entity and a process A relationship between a material entity and a process where the material entity has some causal role that influences the process http://purl.obolibrary.org/obo/GO_0005575 cellular_component A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex). http://purl.obolibrary.org/obo/RO_0002501 causal relation between processes http://purl.obolibrary.org/obo/RO_0002410 causally related to p is causally related to q if and only if p or any part of p and q or any part of q are linked by a chain of events where each event pair is one where the execution of p influences the execution of q. p may be upstream, downstream, part of, or a container of q. http://purl.obolibrary.org/obo/GO_0050964 obsolete detection of electrical stimulus involved in electroception OBSOLETE. The series of events that contribute to electroception in which an electrical stimulus is received and converted into a molecular signal. http://purl.obolibrary.org/obo/RO_0002584 has part structure that is capable of http://purl.obolibrary.org/obo/RO_0002595 causal relation between material entity and a process s 'has part structure that is capable of' p if and only if there exists some part x such that s 'has part' x and x 'capable of' p http://purl.obolibrary.org/obo/GO_1904320 obsolete positive regulation of smooth muscle contraction involved in micturition OBSOLETE. Any process that activates or increases the frequency, rate or extent of smooth muscle contraction involved in micturition. http://purl.obolibrary.org/obo/RO_0002595 causal relation between material entity and a process http://purl.obolibrary.org/obo/RO_0002410 causally related to A relationship that holds between a material entity and a process in which causality is involved, with either the material entity or some part of the material entity exerting some influence over the process, or the process influencing some aspect of the material entity. http://purl.obolibrary.org/obo/CL_0000002 obsolete immortal cell line cell OBSOLETE: A cell line cell that is expected to be capable of an unlimited number of divisions, and is thus able to support indefinite growth/propagation in vitro as part of a immortal cell line. http://purl.obolibrary.org/obo/RO_0002596 capable of regulating http://purl.obolibrary.org/obo/RO_0002500 causal agent in process Holds between c and p if and only if c is capable of some activity a, and a regulates p. http://purl.obolibrary.org/obo/CL_0000004 obsolete cell by organism OBSOLETE: A classification of cells by the organisms within which they are contained. http://purl.obolibrary.org/obo/RO_0002597 capable of negatively regulating http://purl.obolibrary.org/obo/RO_0002596 capable of regulating Holds between c and p if and only if c is capable of some activity a, and a negatively regulates p. http://purl.obolibrary.org/obo/RO_0002598 capable of positively regulating http://purl.obolibrary.org/obo/RO_0002596 capable of regulating Holds between c and p if and only if c is capable of some activity a, and a positively regulates p. http://purl.obolibrary.org/obo/CL_0000009 obsolete fusiform initial Obsolete. Use PO:0000079 from Plant Ontology instead. An elongated cell with approximately wedge-shaped ends, found in the vascular cambium, which gives rise to the elements of the axial system in the secondary vascular tissues. http://purl.obolibrary.org/obo/RO_0002608 process has causal agent http://purl.obolibrary.org/obo/RO_0002410 causally related to Inverse of 'causal agent in process' http://purl.obolibrary.org/obo/CL_0000045 obsolete thymus processed stem cell OBSOLETE (was not defined before being made obsolete). http://purl.obolibrary.org/obo/RO_0002082 simultaneous with http://purl.obolibrary.org/obo/RO_0002081 before or simultaneous with x simultaneous with y iff ω(x) = ω(y) and ω(α ) = ω(α), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point and '=' indicates the same instance in time. http://purl.obolibrary.org/obo/CL_0000046 obsolete bursa processed stem cell OBSOLETE (was not defined before being made obsolete). http://purl.obolibrary.org/obo/RO_0002102 axon synapses in http://purl.obolibrary.org/obo/RO_0002113 has presynaptic terminal in Relation between a neuron and some structure its axon forms (chemical) synapses in. http://purl.obolibrary.org/obo/CL_0000063 obsolete cell by histology OBSOLETE: A classification of cells by their microscopic appearance. http://purl.obolibrary.org/obo/RO_0002132 has fasciculating neuron projection http://purl.obolibrary.org/obo/RO_0002131 overlaps The relation between a neuron projection bundle and a neuron projection that is fasciculated with it. http://purl.obolibrary.org/obo/CL_0000074 obsolete epithem cell Obsolete. Use PO:0000066 from Plant Ontology instead. A cell that constitutes the mesophyll of a hydathode and is located between the xylem endings and the epidermis. Proposed to be involved in the retrieval of solutes from the xylem sap. http://purl.obolibrary.org/obo/RO_0002158 shares ancestor with http://purl.obolibrary.org/obo/RO_0002320 evolutionarily related to two individual entities d1 and d2 stand in a shares_ancestor_with relation if and only if there exists some a such that d1 derived_by_descent_from a and d2 derived_by_descent_from a. http://purl.obolibrary.org/obo/CL_0000093 obsolete osteochondroclast OBSOLETE (was not defined before being made obsolete). http://purl.obolibrary.org/obo/RO_0002206 expressed in http://purl.obolibrary.org/obo/RO_0002330 genomically related to x expressed in y if and only if there is a gene expression process (GO:0010467) that occurs in y, and one of the following holds: (i) x is a gene, and x is transcribed into a transcript as part of the gene expression process (ii) x is a transcript, and the transcription of x is part of the gene expression process (iii) x is a mature gene product such as a protein, and x was translated or otherwise processes from a transcript that was transcribed as part of this gene expression process http://purl.obolibrary.org/obo/CL_0000144 obsolete cell by function OBSOLETE: A classification of cells by their primary end goal or behavior. http://purl.obolibrary.org/obo/RO_0002207 directly develops from http://purl.obolibrary.org/obo/RO_0002202 develops from Candidate definition: x directly_develops from y if and only if there exists some developmental process (GO:0032502) p such that x and y both participate in p, and x is the output of p and y is the input of p, and a substantial portion of the matter of x comes from y, and the start of x is coincident with or after the end of y. http://purl.obolibrary.org/obo/CL_0000156 obsolete antibody secreting cell OBSOLETE: A cell of the lymphoid series that can react with antigen to produce specific cell products called antibodies. Various cell subpopulations, often B cells, can be defined, based on the different classes of immunoglobulins that they synthesize. http://purl.obolibrary.org/obo/RO_0002210 directly develops into http://purl.obolibrary.org/obo/RO_0002203 develops into inverse of directly develops from http://purl.obolibrary.org/obo/CL_0000224 obsolete cell by nuclear number OBSOLETE: A classification of cells by the number of their nuclei. http://purl.obolibrary.org/obo/RO_0002221 surrounds http://purl.obolibrary.org/obo/RO_0002220 adjacent to inverse of surrounded by http://purl.obolibrary.org/obo/CL_0000229 obsolete lymphoblast OBSOLETE (was not defined before being made obsolete). http://purl.obolibrary.org/obo/RO_0002224 starts with http://purl.obolibrary.org/obo/RO_0002222 temporally related to x starts with y if and only if x has part y and the time point at which x starts is equivalent to the time point at which y starts. Formally: α(y) = α(x) ∧ ω(y) < ω(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point. http://purl.obolibrary.org/obo/RO_0002225 develops from part of http://purl.obolibrary.org/obo/RO_0002202 develops from x develops from part of y if and only if there exists some z such that x develops from z and z is part of y http://purl.obolibrary.org/obo/RO_0002226 develops in http://purl.obolibrary.org/obo/RO_0002258 developmentally preceded by x develops_in y if x is located in y whilst x is developing http://purl.obolibrary.org/obo/RO_0002229 ends http://purl.obolibrary.org/obo/BFO_0000050 part of inverse of ends with http://purl.obolibrary.org/obo/CL_0000230 obsolete T lymphoblast OBSOLETE (was not defined before being made obsolete). http://purl.obolibrary.org/obo/RO_0002230 ends with http://purl.obolibrary.org/obo/RO_0002222 temporally related to x ends with y if and only if x has part y and the time point at which x ends is equivalent to the time point at which y ends. Formally: α(y) > α(x) ∧ ω(y) = ω(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point. http://purl.obolibrary.org/obo/CL_0000231 obsolete B lymphoblast OBSOLETE (was not defined before being made obsolete). http://purl.obolibrary.org/obo/RO_0002231 has start location http://purl.obolibrary.org/obo/RO_0002479 has part that occurs in x 'has starts location' y if and only if there exists some process z such that x 'starts with' z and z 'occurs in' y http://purl.obolibrary.org/obo/CL_0000245 obsolete passage cell Obsolete. Use PO:0000353 from Plant Ontology instead. Cell in exodermis or endodermis that remains thin walled when the associated cells develop thick secondary walls. Has casparian strip in endodermis. http://purl.obolibrary.org/obo/RO_0002232 has end location http://purl.obolibrary.org/obo/RO_0002479 has part that occurs in x 'has end location' y if and only if there exists some process z such that x 'ends with' z and z 'occurs in' y http://purl.obolibrary.org/obo/CL_0000248 obsolete microsporocyte Obsolete. Use PO:0020047 from Plant Ontology instead. A diploid (2n) cell that undergoes meiosis and forms four haploid (1n) microspores; also called microspore mother cell and, in seed plants, pollen mother cell. http://purl.obolibrary.org/obo/RO_0002256 developmentally induced by http://purl.obolibrary.org/obo/RO_0002258 developmentally preceded by t1 induced_by t2 if there is a process of developmental induction (GO:0031128) with t1 and t2 as interacting participants. t2 causes t1 to change its fate from a precursor material anatomical entity type T to T', where T' develops_from T http://purl.obolibrary.org/obo/CL_0000250 obsolete megaspore Obsolete. Use PO:0020019 from Plant Ontology instead. A haploid (1n) spore developing into a female gametophyte in heterosporous plants. http://purl.obolibrary.org/obo/RO_0002257 developmentally induces http://purl.obolibrary.org/obo/RO_0002386 has potential to developmentally induce Inverse of developmentally induced by http://purl.obolibrary.org/obo/CL_0000252 obsolete microspore Obsolete. Use PO:0020048 from Plant Ontology instead. A haploid (1n) spore developing into a male gametophyte in heterosporous plants; the uninucleate pollen grain in seed plants. http://purl.obolibrary.org/obo/RO_0002285 developmentally replaces http://purl.obolibrary.org/obo/RO_0002258 developmentally preceded by x developmentally replaces y if and only if there is some developmental process that causes x to move or to cease to exist, and for the site that was occupied by x to become occupied by y, where y either comes into existence in this site or moves to this site from somewhere else http://purl.obolibrary.org/obo/CL_0000254 obsolete egg cell Obsolete. Use PO:0020094 from Plant Ontology instead. The female gamete of plants. http://purl.obolibrary.org/obo/RO_0002292 expresses http://purl.obolibrary.org/obo/RO_0002330 genomically related to y expresses x if and only if there is a gene expression process (GO:0010467) that occurs in y, and one of the following holds: (i) x is a gene, and x is transcribed into a transcript as part of the gene expression process (ii) x is a transcript, and x was transcribed from a gene as part of the gene expression process (iii) x is a mature gene product (protein or RNA), and x was translated or otherwise processed from a transcript that was transcribed as part of the gene expression process. http://purl.obolibrary.org/obo/CL_0000258 obsolete fiber tracheid Obsolete. Use PO:0000355 from Plant Ontology instead. A fiber like tracheid in the secondary xylem; commonly thick walled, with pointed ends and bordered pits that have lenticular to slit like apertures. http://purl.obolibrary.org/obo/RO_0002295 results in developmental progression of http://purl.obolibrary.org/obo/RO_0002324 developmentally related to p results in the developmental progression of s iff p is a developmental process and s is an anatomical entity and p causes s to undergo a change in state at some point along its natural developmental cycle (this cycle starts with its formation, through the mature structure, and ends with its loss). http://purl.obolibrary.org/obo/CL_0000260 obsolete mucilage cell Obsolete. Use PO:0000373 from Plant Ontology instead. Cell containing mucilages or gums or similar carbohydrate material characterized by the property of swelling in water. http://purl.obolibrary.org/obo/CL_0000262 obsolete guard mother cell Obsolete. Use PO:0000351 from Plant Ontology instead. An epidermal cell that divides to produce the guard cells. http://purl.obolibrary.org/obo/RO_0002296 results in development of http://purl.obolibrary.org/obo/RO_0002295 results in developmental progression of p 'results in development of' c if and only if p is a developmental process and p results in the state of c changing from its initial state as a primordium or anlage through its mature state and to its final state. http://purl.obolibrary.org/obo/CL_0000264 obsolete phloem initial Obsolete. Use PO:0000400 from Plant Ontology instead. A cambial cell on the phloem side of the cambial zone that is the source of one or more cells arising by periclinal divisions and differentiating into phloem elements with or without additional divisions in various planes. http://purl.obolibrary.org/obo/RO_0002298 results in morphogenesis of http://purl.obolibrary.org/obo/RO_0002295 results in developmental progression of The relationship that links an entity with the process that results in the formation and shaping of that entity over time from an immature to a mature state. http://purl.obolibrary.org/obo/CL_0000266 obsolete meristemoid Obsolete. Use PO:0004011 from Plant Ontology instead. A cell constituting an active locus of meristematic activity in a tissue composed of somewhat older, differentiating cells. http://purl.obolibrary.org/obo/RO_0002299 results in maturation of http://purl.obolibrary.org/obo/RO_0002295 results in developmental progression of The relationship that links an entity with a process that results in the progression of the entity over time that is independent of changes in it's shape and results in an end point state of that entity. http://purl.obolibrary.org/obo/CL_0000268 obsolete sieve element Obsolete. Consult Plant Ontology instead. The cell in the phloem tissue concerned with mainly longitudinal conduction of food materials. Classified into sieve cell and sieve tube member. http://purl.obolibrary.org/obo/RO_0015003 subcluster of http://purl.obolibrary.org/obo/BFO_0000050 part of A relation between a group and another group it is part of but does not fully constitute. http://purl.obolibrary.org/obo/CL_0000270 obsolete subsidiary cell Obsolete. Use PO:0000284 from Plant Ontology instead. An epidermal cell associated with a stoma and at least morphologically distinguishable from the epidermal cells composing the groundmass of the tissue. http://purl.obolibrary.org/obo/RO_0015015 has high plasma membrane amount http://purl.obolibrary.org/obo/RO_0002104 has plasma membrane part A relation between a cell and molecule or complex such that every instance of the cell has a high number of instances of that molecule expressed on the cell surface. http://purl.obolibrary.org/obo/CL_0000272 obsolete cambial initial OBSOLETE, use term from Plant Ontology. A cell localized in the vascular cambium or phellogen. Its periclinal division can contribute cells either to the outside or to the inside of the axis; in vascular cambium, classified into fusiform initials (source of axial cells of xylem and phloem) and ray initials (source of the ray cells). http://purl.obolibrary.org/obo/RO_0015016 has low plasma membrane amount http://purl.obolibrary.org/obo/RO_0002104 has plasma membrane part A relation between a cell and molecule or complex such that every instance of the cell has a low number of instances of that molecule expressed on the cell surface. http://purl.obolibrary.org/obo/CL_0000276 obsolete sclerenchyma cell Obsolete. Use PO:0000077 from Plant Ontology instead. Cell variable in form and size, being more or less thick, often lignified, secondary walls. Belongs to the category of subcells and may or may not be devoid of protoplast at maturity. http://purl.obolibrary.org/obo/RO_0013007 has sensory dendrite in http://purl.obolibrary.org/obo/RO_0002360 has dendrite location Relation between a sensory neuron and some structure in which it receives sensory input via a sensory dendrite. http://purl.obolibrary.org/obo/CL_0000277 obsolete prestalk I cell OBSOLETE: Initial population of prestalk cells that activate the ecmA promoter at the mound stage and that presumably further differentiate into pstA and pstO cells. http://purl.obolibrary.org/obo/RO_0002315 results in acquisition of features of http://purl.obolibrary.org/obo/RO_0002295 results in developmental progression of The relationship that links a specified entity with the process that results in an unspecified entity acquiring the features and characteristics of the specified entity http://purl.obolibrary.org/obo/CL_0000278 obsolete central cell Obsolete. Use PO:0020090 from Plant Ontology instead. OBSOLETED, use term from Plant Ontology. A cell containing the two polar nuclei which, after double fertilization, will develop into the endosperm. http://purl.obolibrary.org/obo/RO_0002332 regulates levels of http://purl.obolibrary.org/obo/RO_0002328 functionally related to p regulates levels of c if p regulates some amount (PATO:0000070) of c http://purl.obolibrary.org/obo/CL_0000280 obsolete generative cell Obsolete. Use PO:0020097 from Plant Ontology instead. The cell that will give rise to the generative nuclei which will participate in fertilization. http://purl.obolibrary.org/obo/RO_0002338 has target start location http://purl.obolibrary.org/obo/RO_0002344 results in transport to from or in This relationship holds between p and l when p is a transport or localization process in which the outcome is to move some cargo c from some initial location l to some destination. http://purl.obolibrary.org/obo/CL_0000282 obsolete trichome Obsolete. Use PO:0000282 from Plant Ontology instead. An outgrowth from the epidermis. Trichomes vary in size and complexity and include hairs, scales, and other structures and may be glandular. In Arabidopsis, patterning of trichome development is not random but does not appear to be lineage-based like stomata. http://purl.obolibrary.org/obo/RO_0002339 has target end location http://purl.obolibrary.org/obo/RO_0002344 results in transport to from or in This relationship holds between p and l when p is a transport or localization process in which the outcome is to move some cargo c from a an initial location to some destination l. http://purl.obolibrary.org/obo/CL_0000284 obsolete companion cell Obsolete. Use PO:0000071 from Plant Ontology instead. A specialized parenchyma cell associated with a sieve-tube member in angiosperm phloem and arising from the same mother cell as the sieve-tube member. http://purl.obolibrary.org/obo/RO_0002341 results in transport along http://purl.obolibrary.org/obo/RO_0002337 related via localization to Holds between p and l when p is a transportation or localization process and the outcome of this process is to move c from one location to another, and the route taken by c follows a path that is aligned_with l http://purl.obolibrary.org/obo/CL_0000288 obsolete synergid Obsolete. Use PO:0000191 from Plant Ontology instead. A cell in the micropylar end of the embryo sac associated with the egg in the egg apparatus of angiosperms. Plays a vital role in fertilization. http://purl.obolibrary.org/obo/RO_0002342 results in transport across http://purl.obolibrary.org/obo/RO_0002344 results in transport to from or in Holds between p and m when p is a transportation or localization process and the outcome of this process is to move c from one location to another, and the route taken by c follows a path that crosses m. http://purl.obolibrary.org/obo/CL_0000290 obsolete xylem fiber cell Obsolete. Use PO:0000274 from Plant Ontology instead. A fiber of the xylem tissue, Two types are recognized in the secondary xylem: fiber tracheids and libriform fibers. http://purl.obolibrary.org/obo/RO_0002386 has potential to developmentally induce http://purl.obolibrary.org/obo/RO_0002384 has developmental potential involving x has potential to developmentally induce y iff x developmentally induces y or x is capable of developmentally inducing y http://purl.obolibrary.org/obo/CL_0000292 obsolete guard cell Obsolete. Use PO:0000293 from Plant Ontology instead. One of a pair of cells flanking the stomatal pore and causing the opening and closing of the pore by changes in turgor. http://purl.obolibrary.org/obo/RO_0002413 provides input for http://purl.obolibrary.org/obo/RO_0002414 transitively provides input for p provides input for q iff p is immediately causally upstream of q, and there exists some c such that p has_output c and q has_input c. http://purl.obolibrary.org/obo/RO_0002414 transitively provides input for http://purl.obolibrary.org/obo/RO_0004047 causally upstream of or within, positive effect transitive form of directly_provides_input_for http://purl.obolibrary.org/obo/CL_0000294 obsolete sieve cell Obsolete. Consult Plant Ontology instead. A type of sieve element that has relatively undifferentiated sieve areas (with narrow pores), rather uniform in structure on all walls; that is, there are no sieve plates. Typical of gymnosperms and lower vascular plants. http://purl.obolibrary.org/obo/RO_0002428 involved in regulation of http://purl.obolibrary.org/obo/RO_0002431 involved in or involved in regulation of c involved in regulation of p if c is involved in some p' and p' regulates some p http://purl.obolibrary.org/obo/CL_0000296 obsolete vegetative cell Obsolete. Use PO:0020099 from Plant Ontology instead. Cell type formed after the first mitotic division of the microgametophye, The nucleus of this cell migrates to the tip of the pollen tube after germination and disintegrates when the pollen tube penetrates the nucellus. http://purl.obolibrary.org/obo/RO_0002565 results in movement of http://purl.obolibrary.org/obo/RO_0040036 results in changes to anatomical or cellular structure Holds between p and c when p is locomotion process and the outcome of this process is the change of location of c http://purl.obolibrary.org/obo/CL_0000297 obsolete socket cell Obsolete. Use PO:0000115 from Plant Ontology instead. A cell that surrounds a trichome and provides support for the trichome. http://purl.obolibrary.org/obo/RO_0002570 conduit for http://purl.obolibrary.org/obo/RO_0002131 overlaps x is a conduit for y iff y overlaps through the lumen_of of x, and y has parts on either side of the lumen of x. http://purl.obolibrary.org/obo/CL_0000298 obsolete xylem element Obsolete. Use PO:0000273 from Plant Ontology instead. A cell composing the xylem. http://purl.obolibrary.org/obo/RO_0002586 results in breakdown of http://purl.obolibrary.org/obo/RO_0002233 has input p results in breakdown of c if and only if the execution of p leads to c no longer being present at the end of p http://purl.obolibrary.org/obo/CL_0000299 obsolete trichoblast OBSOLETED. Commonly used for a cell in root epidermis that gives rise to a root hair. The daughter cell produced by the asymmetric division of a root epidermal cell that gives rise to a root hair. http://purl.obolibrary.org/obo/RO_0002592 results in organization of http://purl.obolibrary.org/obo/RO_0040036 results in changes to anatomical or cellular structure p results in organization of c iff p results in the assembly, arrangement of constituent parts, or disassembly of c http://purl.obolibrary.org/obo/CL_0000302 obsolete IgM B cell OBSOLETE (was not defined before being made obsolete). http://purl.obolibrary.org/obo/RO_0002343 results in growth of http://purl.obolibrary.org/obo/RO_0002295 results in developmental progression of http://purl.obolibrary.org/obo/CL_0000303 obsolete IgG B cell OBSOLETE (was not defined before being made obsolete). http://purl.obolibrary.org/obo/RO_0002297 results in formation of anatomical entity http://purl.obolibrary.org/obo/RO_0002295 results in developmental progression of http://purl.obolibrary.org/obo/CL_0000304 obsolete IgA B cell OBSOLETE (was not defined before being made obsolete). http://purl.obolibrary.org/obo/RO_0002287 part of developmental precursor of http://purl.obolibrary.org/obo/RO_0002286 developmentally succeeded by http://purl.obolibrary.org/obo/CL_0000305 obsolete IgE B cell OBSOLETE (was not defined before being made obsolete). http://purl.obolibrary.org/obo/RO_0002405 immediately causally downstream of http://purl.obolibrary.org/obo/RO_0002404 causally downstream of http://purl.obolibrary.org/obo/CL_0000316 obsolete ray initial Obsolete. Use PO:0000082 from Plant Ontology instead. A meristemic ray cell in the vascular cambium that gives rise to ray cells of the secondary xylem and secondary phloem. http://purl.obolibrary.org/obo/RO_0002006 has synaptic terminal of http://purl.obolibrary.org/obo/RO_0002131 overlaps http://purl.obolibrary.org/obo/CL_0000320 obsolete megasporocyte Obsolete. Use PO:0000431 from Plant Ontology instead. A diploid (2n) cell that undergoes meiosis and produces four haploid (1n) megaspores; also called megaspore mother cell. http://purl.obolibrary.org/obo/RO_0002360 has dendrite location http://purl.obolibrary.org/obo/RO_0002131 overlaps http://purl.obolibrary.org/obo/RO_0002354 formed as result of http://purl.obolibrary.org/obo/RO_0002353 output of http://purl.obolibrary.org/obo/CL_0000330 obsolete collenchymal cell Obsolete. Use PO:0000075 from Plant Ontology instead. An elongated living cell with unevenly thickened nonlignified primary walls. http://purl.obolibrary.org/obo/RO_0002485 receives input from http://purl.obolibrary.org/obo/RO_0002170 connected to http://purl.obolibrary.org/obo/CL_0000331 obsolete tracheid Obsolete. Use PO:0000301 from Plant Ontology instead. A tracheary element of the xylem that has no perforations, as contrasted with a vessel member. May occur in primary and in secondary xylem. May have any kind of secondary wall thickening found in tracheary elements. http://purl.obolibrary.org/obo/RO_0002486 sends output to http://purl.obolibrary.org/obo/RO_0002170 connected to http://purl.obolibrary.org/obo/CL_0000332 obsolete atrichoblast OBSOLETE, use term from Plant Ontology. A cell formed after asymmetric division of root epidermal cell that does not give rise to a root hair. http://purl.obolibrary.org/obo/RO_0004046 causally upstream of or within, negative effect http://purl.obolibrary.org/obo/RO_0002418 causally upstream of or within http://purl.obolibrary.org/obo/CL_0000363 obsolete axial cell Obsolete. Use PO:0000081 from Plant Ontology instead. OBSOLETE, use term from the Plant Ontology. A secondary vascular cell that develops from the fusiform cambial initials and oriented with their longest diameter parallel with the main axis of stem or root. These cells make up the axial system, also known as vertical or longitudinal system. http://purl.obolibrary.org/obo/RO_0004047 causally upstream of or within, positive effect http://purl.obolibrary.org/obo/RO_0002418 causally upstream of or within http://purl.obolibrary.org/obo/CL_0000364 obsolete ray cell Obsolete. Consult Plant Ontology. A cell that develops from the ray initial and composes all rays (panels of tissue variable in height and width, formed by the ray initials in the vascular cambium and extending radially in the secondary xylem and secondary phloem) in the secondary vascular tissues. http://purl.obolibrary.org/obo/uberon/core#sexually_homologous_to sexually_homologous_to http://purl.obolibrary.org/obo/RO_0002158 shares ancestor with http://purl.obolibrary.org/obo/CL_0000366 obsolete sperm cell (sensu Viridiplantae) Obsolete. Use PO:0000084 from Plant Ontology instead. Male gamete, part of male germ unit. http://purl.obolibrary.org/obo/RO_0002588 results in assembly of http://purl.obolibrary.org/obo/RO_0002592 results in organization of http://purl.obolibrary.org/obo/CL_0000368 obsolete myrosin cell Obsolete. Use PO:0000352 from Plant Ontology instead. Cell containing glucosinolates ('mustard oil glucosides') and myrosinases, enzymes hydrolyzing the glucosinolates. Occurs in eleven dicotyledon families, the two largest of which are the Brassicaceae and Euphorbiaceae. http://purl.obolibrary.org/obo/RO_0002344 results in transport to from or in http://purl.obolibrary.org/obo/RO_0002337 related via localization to http://purl.obolibrary.org/obo/CL_0000370 obsolete transfer cell Obsolete. Use PO:0000078 from Plant Ontology instead. Parenchyma cell with the wall ingrowth (or invaginations) that increase the surface of the plasmalemma. Appears to be specialized for short-distance transfer of solutes. http://purl.obolibrary.org/obo/RO_0002590 results in disassembly of http://purl.obolibrary.org/obo/RO_0002592 results in organization of http://purl.obolibrary.org/obo/CL_0000399 obsolete phloem element Obsolete. Consult Plant Ontology instead. OBSOLETED, not defined prior to obsoletion. http://purl.obolibrary.org/obo/RO_0012008 results in fusion of http://purl.obolibrary.org/obo/RO_0002592 results in organization of http://purl.obolibrary.org/obo/CL_0000400 obsolete pavement cell Obsolete. Use PO:0000332 from Plant Ontology instead. An epidermal cell with a characteristic convoluted anticlinal cell wall that gives a jigsaw like appearance to the lamina. http://purl.obolibrary.org/obo/RO_0015006 different in magnitude relative to q1 different_in_magnitude_relative_to q2 if and only if magnitude(q1) NOT =~ magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale. http://purl.obolibrary.org/obo/CL_0000414 obsolete cell by ploidy OBSOLETE: A classification of cells by the number of haploid genome equivalents of their nucleus or nuclei. http://purl.obolibrary.org/obo/BFO_0000066 occurs in b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t http://purl.obolibrary.org/obo/CL_0000433 obsolete functional megaspore Obsolete. Use PO:0000244 from Plant Ontology instead. In monosporic and bisporic megasporogenesis: the megaspore(s) that will undergo megagametogenesis. http://purl.obolibrary.org/obo/RO_0002323 mereotopologically related to A mereological relationship or a topological relationship http://purl.obolibrary.org/obo/RO_0002328 functionally related to A grouping relationship for any relationship directly involving a function, or that holds because of a function of one of the related entities. http://purl.obolibrary.org/obo/CL_0000455 obsolete starch sheath cell Obsolete. Use PO:0004531 from Plant Ontology instead. A cell characterized by conspicuous and rather stable accumulation of starch. http://purl.obolibrary.org/obo/cl#has_high_plasma_membrane_amount obsolete has_high_plasma_membrane_amount OBSOLETE A relation between a cell and molecule or complex such that every instance of the cell has a high number of instances of that molecule expressed on the cell surface. For the formal definition, see Masci et al (PMID:19243617). http://purl.obolibrary.org/obo/cl#has_low_plasma_membrane_amount obsolete has_low_plasma_membrane_amount OBSOLETE A relation between a cell and molecule or complex such that every instance of the cell has a low number of instances of that molecule expressed on the cell surface. For the formal definition, see Masci et al (PMID:19243617). http://purl.obolibrary.org/obo/CL_0000472 obsolete chlorenchyma cell Obsolete. Use PO:0000076 from Plant Ontology instead. OBSOLETE, use term from Plant Ontology. Parenchyma cells containing chloroplasts; a component of leaf mesophyll and other green parenchyma tissue. http://purl.obolibrary.org/obo/RO_0015011 has cross section s3 has_cross_section s3 if and only if : there exists some 2d plane that intersects the bearer of s3, and the impression of s3 upon that plane has shape quality s2. http://purl.obolibrary.org/obo/CL_0000475 obsolete degenerate megaspore Obsolete. Use PO:0000245 from Plant Ontology instead. In monosporic and bisporic megasporogenesis: the megaspore(s) that do not participate in megagametogenesis. http://purl.obolibrary.org/obo/RO_0020104 is neuron This property only applies to neurons http://purl.obolibrary.org/obo/CL_0000491 obsolete cytotoxic T cell OBSOLETE: A cell responsible for spontaneous cytotoxicity of a variety of tumor cells without prior immunization. These natural killer cells are found in non-immune humans and experimental animals and are thought by some to be the same as killer cells (killing by antibody-dependent cell cytotoxicity), but they can also kill in the absence of antibody. http://purl.obolibrary.org/obo/RO_0020105 is anatomical entity This property only applies to anatomical entities. http://purl.obolibrary.org/obo/CL_0000493 obsolete regulatory T cell OBSOLETE: Subpopulation of CD4+ cells which induce CD8+ suppressor T cells to suppress antibody production by B cells. They also stimulate other cellular immune responses. http://purl.obolibrary.org/obo/RO_0002330 genomically related to holds between two entities when some genome-level process such as gene expression is involved. This includes transcriptional, spliceosomal events. These relations can be used between either macromolecule entities (such as regions of nucleic acid) or between their abstract informational counterparts. http://purl.obolibrary.org/obo/CL_0000522 obsolete spore OBSOLETE: The reproductive structure of bacteria, fungi and cryptograms. http://purl.obolibrary.org/obo/RO_0002134 innervates Relation between a 'neuron projection bundle' and a region in which one or more of its component neuron projections either synapses to targets or receives synaptic input. T innervates some R Expands_to: T has_fasciculating_neuron_projection that synapse_in some R. http://purl.obolibrary.org/obo/CL_0000537 obsolete antipodal cell Obsolete. Use PO:0020093 from Plant Ontology instead. OBSOLETE, use term from plant ontology. A cell located at the chalazal end of the mature embryo sac in angiosperms. http://purl.obolibrary.org/obo/RO_0002005 innervated by relation between an anatomical structure and a neuron projection bundle that has synaptic terminals in the structure. http://purl.obolibrary.org/obo/CL_0000538 obsolete epidermal initial Obsolete. Use PO:0000349 from Plant Ontology instead. A relatively unspecialized cell that will give rise to specialized cell types of the epidermis. http://purl.obolibrary.org/obo/CL_0000539 obsolete idioblast OBSOLETE: A cell in a tissue that markedly differs in form, size, or contents from other cells in the same tissue. http://purl.obolibrary.org/obo/RO_0002410 causally related to relation that links two events, processes, states, or objects such that one event, process, state, or object (a cause) contributes to the production of another event, process, state, or object (an effect) where the cause is partly or wholly responsible for the effect, and the effect is partly or wholly dependent on the cause. http://purl.obolibrary.org/obo/CL_0000543 obsolete sieve tube member Obsolete. Use PO:0000289 from Plant Ontology instead. One of the series of cellular components of a sieve tube. It shows a more or less pronounced differentiation between sieve plates (wide pores) and lateral sieve areas (narrow pores). Also sieve tube element and the obsolete sieve tube segment. http://purl.obolibrary.org/obo/RO_0002479 has part that occurs in p has part that occurs in c if and only if there exists some p1, such that p has_part p1, and p1 occurs in c. http://purl.obolibrary.org/obo/CL_0000585 obsolete null cell OBSOLETE: A class of lymphocytes characterized by the lack of surface markers specific for either T or B cells. http://purl.obolibrary.org/obo/RO_0002337 related via localization to A relationship that holds via some process of localization http://purl.obolibrary.org/obo/CL_0000616 obsolete sporangiospore OBSOLETE: A walled spore produced in a sporangium. http://purl.obolibrary.org/obo/RO_0002222 temporally related to http://purl.obolibrary.org/obo/CL_4030044 has_not_completed http://purl.obolibrary.org/obo/CL_0000620 obsolete zoospore OBSOLETE: A sporangiospore that is motile, having flagella. http://purl.obolibrary.org/obo/CL_4030046 lacks_plasma_membrane_part http://purl.obolibrary.org/obo/RO_0002502 depends on http://purl.obolibrary.org/obo/RO_0015010 has relative magnitude http://purl.obolibrary.org/obo/CL_0000668 obsolete parenchymal cell OBSOLETE: The cell characteristic of an organ, as distinguished from associated connective or supporting tissues. http://purl.obolibrary.org/obo/uberon/core#channel_for channel for http://purl.obolibrary.org/obo/CL_0000672 obsolete tracheary element Obsolete. Use PO:0000290 from Plant Ontology instead. A water conducting cell, tracheid or vessel member. http://purl.obolibrary.org/obo/uberon/core#protects protects http://purl.obolibrary.org/obo/CL_0000685 obsolete meristematic cell Obsolete. Use PO:0004010 from Plant Ontology instead. A cell synthesizing protoplasm and producing new cells by division and with only a primary cell wall. http://purl.obolibrary.org/obo/uberon/core#subdivision_of subdivision of http://purl.obolibrary.org/obo/CL_0002245 obsolete null lymphocyte OBSOLETE: A lymphocyte that lacks T or B cell surface markers. http://purl.obolibrary.org/obo/RO_0015002 exemplar data of http://purl.obolibrary.org/obo/CL_0002276 obsolete PP cell of pancreatic acinus OBSOLETE: A PP cell located in the pancreatic acinus. Obsoleted due to a lack of published evidence that this cell type is actually found in the pancreatic acinus. http://purl.obolibrary.org/obo/GOREL_0002003 results_in_distribution_of http://purl.obolibrary.org/obo/CL_0002392 obsolete plant spore Obsolete. Use PO:0025017 from Plant Ontology instead. A plant cell that arises through meiosis and develops into a gametophyte. http://purl.obolibrary.org/obo/CL_0005016 obsolete apical cell Obsolete. Use PO:0030007 from Plant Ontology instead. The apical cell is the upper cell formed after the first division of a plant zygote. http://purl.obolibrary.org/obo/CL_0005017 obsolete plant basal cell Obsolete. Use PO:0002002 from Plant Ontology instead. The lower cell formed after the first division of a plant zygote. http://purl.obolibrary.org/obo/CL_0007014 obsolete cell line cell OBSOLETE: A cultured cell that has been passaged at least one time in culture. http://purl.obolibrary.org/obo/CL_0007015 obsolete mortal cell line cell OBSOLETE: A cell line cell that is expected to be capable of replicating a limited number of times in culture before undergoing senescence. Mortal cell line cells cannot be propagated indefinitely (as immortal cell line cells can). http://purl.obolibrary.org/obo/CL_1000316 obsolete goblet cell of epithelium of small intestine OBSOLETE: A goblet cell that is part of the epithelium of small intestine. http://purl.obolibrary.org/obo/CL_1000318 obsolete small intestine crypt goblet cell A goblet cell that is part of the epithelium of crypt of lieberkuhn of small intestine. http://purl.obolibrary.org/obo/CL_1000319 obsolete goblet cell of epithelium proper of small intestine OBSOLETE: A goblet cell that is part of the epithelium proper of small intestine. http://purl.obolibrary.org/obo/CL_1000328 obsolete goblet cell of epithelium proper of large intestine OBSOLETE: A goblet cell that is part of the epithelium proper of large intestine. http://purl.obolibrary.org/obo/CL_1001583 obsolete breast adipocyte OBSOLETE: Adipocytes found in the subcutaneous adipose tissue of breast. The breast consists of three main components, the skin, the subcutaneous adipose tissue and the functional glandular tissue that comprises both parenchyma and stroma. http://purl.obolibrary.org/obo/UBERON_0000000 processual entity An occurrent [span:Occurrent] that exists in time by occurring or happening, has temporal parts and always involves and depends on some entity. http://purl.obolibrary.org/obo/UBERON_0001062 anatomical entity Biological entity that is either an individual member of a biological species or constitutes the structural organization of an individual member of a biological species. http://purl.obolibrary.org/obo/PR_000003466 perforin-1 A protein that is a translation product of the human PRF1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000007785 glutamate decarboxylase 1 A protein that is a translation product of the human GAD1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/CL_4023073 obsolete choroid plexus cell OBSOLETE. A cell that is part of the choroid plexus. http://identifiers.org/ncbigene/16572 Kif5a (Mmus) https://purl.brain-bican.org/ontology/mbao/MBA_141 Periventricular region https://purl.brain-bican.org/ontology/mbao/MBA_826 Pallidum, medial region https://purl.brain-bican.org/ontology/mbao/MBA_768 cerebrum related http://identifiers.org/ncbigene/72893 2900040C04Rik (Mmus) http://identifiers.org/ncbigene/214944 Mob3b (Mmus) http://identifiers.org/ncbigene/75172 Ccdc146 (Mmus) http://identifiers.org/ncbigene/14399 Gabra6 (Mmus) http://identifiers.org/ncbigene/13609 S1pr1 (Mmus) http://identifiers.org/ncbigene/17926 Myoc (Mmus) http://identifiers.org/ncbigene/13051 Cx3cr1 (Mmus) http://purl.obolibrary.org/obo/CL_0008029 obsolete inhibitory neuron http://purl.obolibrary.org/obo/CL_0008030 obsolete excitatory neuron http://identifiers.org/ncbigene/18755 Prkch (Mmus) http://identifiers.org/ncbigene/231633 Tmem119 (Mmus) http://purl.obolibrary.org/obo/IAO_0000030 information content entity http://identifiers.org/ncbigene/208898 Unc13c (Mmus) http://purl.obolibrary.org/obo/CL_0000054 obsolete bone matrix secreting cell http://purl.obolibrary.org/obo/CL_0000073 obsolete barrier epithelial cell http://purl.obolibrary.org/obo/CL_0000085 obsolete germ line stem cell (sensu Vertebrata) http://purl.obolibrary.org/obo/CL_0000086 obsolete germ line stem cell (sensu Nematoda and Protostomia) http://purl.obolibrary.org/obo/CL_0000087 obsolete male germ line stem cell (sensu Nematoda and Protostomia) http://purl.obolibrary.org/obo/CL_0000088 obsolete female germ line stem cell (sensu Nematoda and Protostomia) http://purl.obolibrary.org/obo/CL_0000089 obsolete male germ line stem cell (sensu Vertebrata) http://purl.obolibrary.org/obo/CL_0000090 obsolete female germ line stem cell (sensu Vertebrata) http://purl.obolibrary.org/obo/CL_0000124 obsolete glial cell (sensu Nematoda and Protostomia) http://purl.obolibrary.org/obo/CL_0000161 obsolete acid secreting cell http://purl.obolibrary.org/obo/CL_0000217 obsolete insulating cell http://purl.obolibrary.org/obo/CL_0000259 obsolete aggregate cell http://purl.obolibrary.org/obo/CL_0000261 obsolete anterior cell http://purl.obolibrary.org/obo/CL_0000263 obsolete vegetative cell (sensu Mycetozoa) http://purl.obolibrary.org/obo/CL_0000265 obsolete anterior like cell http://purl.obolibrary.org/obo/CL_0000267 obsolete prespore cell http://purl.obolibrary.org/obo/CL_0000269 obsolete prestalk cell http://purl.obolibrary.org/obo/CL_0000271 obsolete prestalk A cell http://purl.obolibrary.org/obo/CL_0000273 obsolete prestalk AB cell http://purl.obolibrary.org/obo/CL_0000275 obsolete prestalk B cell http://purl.obolibrary.org/obo/CL_0000279 obsolete prestalk 0 cell http://purl.obolibrary.org/obo/CL_0000281 obsolete pstAB/ALC http://purl.obolibrary.org/obo/CL_0000283 obsolete pstO/ALC http://purl.obolibrary.org/obo/CL_0000285 obsolete stalk cell http://purl.obolibrary.org/obo/CL_0000289 obsolete chemotactic amoeboid cell (sensu Mycetozoa) http://purl.obolibrary.org/obo/CL_0000291 obsolete spore (sensu Mycetozoa) http://purl.obolibrary.org/obo/CL_0000321 obsolete seminal fluid secreting cell http://purl.obolibrary.org/obo/CL_0000328 obsolete myelin accumulating cell http://purl.obolibrary.org/obo/CL_0000381 obsolete neurosecretory neuron http://purl.obolibrary.org/obo/CL_0000386 obsolete attachment cell http://purl.obolibrary.org/obo/CL_0000391 obsolete podocyte (sensu Diptera) http://purl.obolibrary.org/obo/CL_0000398 obsolete polygonal cell http://purl.obolibrary.org/obo/CL_0000401 obsolete macrophage (sensu Diptera) http://purl.obolibrary.org/obo/CL_0000405 obsolete neuroepidermoblast http://purl.obolibrary.org/obo/CL_0000409 obsolete scolopidial sheath cell http://purl.obolibrary.org/obo/CL_0000426 obsolete scaffold cell http://purl.obolibrary.org/obo/CL_0000452 obsolete thyroid hormone secreting cell http://purl.obolibrary.org/obo/CL_0000512 obsolete paracrine cell http://purl.obolibrary.org/obo/CL_0000555 obsolete neuronal brush cell http://purl.obolibrary.org/obo/CL_0000663 obsolete valve cell http://purl.obolibrary.org/obo/CL_0000664 obsolete closable valve cell http://purl.obolibrary.org/obo/CL_0000665 obsolete permanently open valve cell http://purl.obolibrary.org/obo/CL_0000727 obsolete primary pigment cell http://purl.obolibrary.org/obo/CL_0000728 obsolete secondary pigment cell http://purl.obolibrary.org/obo/CL_0000729 obsolete tertiary pigment cell http://purl.obolibrary.org/obo/CL_0000734 obsolete embryonic gland plasmatocyte http://purl.obolibrary.org/obo/CL_0000736 obsolete embryonic gland hemocyte http://purl.obolibrary.org/obo/CL_1000451 obsolete epithelial cell of visceral layer of glomerular capsule http://identifiers.org/ncbigene/14812 Grin2b (Mmus) https://purl.brain-bican.org/ontology/mbao/MBA_864 Thalamus, sensory-motor cortex related http://identifiers.org/ncbigene/14800 Gria2 (Mmus) http://identifiers.org/ncbigene/78896 Ecrg4 (Mmus) http://identifiers.org/ncbigene/58222 Rab37 (Mmus) http://identifiers.org/ncbigene/76747 Dapl1 (Mmus) http://purl.obolibrary.org/obo/CL_0000012 obsolete cell by class http://purl.obolibrary.org/obo/CL_0000013 obsolete dentine secreting cell http://purl.obolibrary.org/obo/CL_0000070 obsolete epithelial cell of gland http://purl.obolibrary.org/obo/CL_0000194 obsolete nodal cardiac cell http://purl.obolibrary.org/obo/CL_0000195 obsolete Purkinje fiber http://purl.obolibrary.org/obo/CL_0000220 obsolete cell by lineage http://purl.obolibrary.org/obo/CL_0000344 obsolete non-visual cell (sensu Vertebrata) http://purl.obolibrary.org/obo/CL_0000375 obsolete osteoprogenitor cell http://purl.obolibrary.org/obo/CL_0000610 obsolete plant cell http://purl.obolibrary.org/obo/CL_0000698 obsolete paraganglial cell http://purl.obolibrary.org/obo/NCBITaxon_1 root http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CL_0008042 tanycyte of subfornical organ http://purl.obolibrary.org/obo/CL_0002085 tanycyte A tanycyte of the subfornical organ (SFO). These cells extend long and slender fibers extending from their cell bodies in the ependyma toward fenestrated capillaries associated with the SFO, where they form a dense network surrounding these capillaries. http://purl.obolibrary.org/obo/CL_0008044 tanycyte of area postrema http://purl.obolibrary.org/obo/CL_0002085 tanycyte A tanycyte of the area postrema (AP). These cells extend long and slender fibers extending from their cell bodies in the ependyma toward fenestrated capillaries associated with the AP, where they form a dense network surrounding these capillaries. http://purl.obolibrary.org/obo/CL_0008045 tanycyte of subcommissural organ http://purl.obolibrary.org/obo/CL_0002085 tanycyte A tanycyte of the subcommisural organ (SCO). These cells extend long and slender fibers extending from their cell bodies in the ependyma toward fenestrated capillaries associated with the SCO, where they form a dense network surrounding these capillaries. http://purl.obolibrary.org/obo/CL_0008053 circumventricular organ capillary endothelial cell http://purl.obolibrary.org/obo/CL_2000044 brain microvascular endothelial cell A capillary endothelial cell that is part of the circumventricular organs (CVOs), characterized by fenestrations that facilitate selective permeability to molecules, distinguishing it from the non-fenestrated endothelial cells of the blood-brain barrier. This cell is integral to the unique vascular structure of CVOs, which lack a traditional blood-brain barrier. It enables bidirectional exchange of polar molecules between blood and neural tissue, supporting neuroendocrine signaling, fluid balance, and immune responses. It is marked by the expression of PLVAP, a component of the fenestral diaphragm, in both rodents and humans. http://purl.obolibrary.org/obo/CL_0008055 respiratory tract secretory epithelial cell http://purl.obolibrary.org/obo/CL_0002368 respiratory tract epithelial cell A secretory epithelial cell of the respiratory tract epithelium. These cells have an endodermal origin. http://purl.obolibrary.org/obo/CL_4047036 stomach smooth muscle circular layer cell http://purl.obolibrary.org/obo/CL_4047034 smooth muscle cell of stomach A smooth muscle cell located in the middle layer of the muscularis externa of the stomach wall. This cell is arranged concentrically with the stomach's longitudinal axis, forming a continuous sheet of contractile tissue. It is fusiform in shape, containing actin and myosin filaments that enable contraction without striations. This cell contributes to the mechanical digestion and movement of food within the stomach through coordinated contractions, and plays a role in forming the pyloric sphincter in the pyloric region. http://purl.obolibrary.org/obo/CL_4047038 dogiel type I neuron http://purl.obolibrary.org/obo/CL_0007011 enteric neuron A multipolar neuron in the myenteric plexus of the gastrointestinal tract, characterized by a small to medium-sized cell body and multiple short dendrites. This neuron exhibits fast excitatory postsynaptic potentials and can be classified into stubby, spiny and hairy subtypes based on dendritic morphology. (Brehmer, 2021) http://purl.obolibrary.org/obo/CL_4047042 type 1 myenteric plexus glia http://purl.obolibrary.org/obo/CL_4040002 enteroglial cell An enteric glial cell located within the myenteric ganglia of the gastrointestinal tract. This cell has a small somata and has very short, irregularly branched processes that surround neuron cell bodies, giving it a protoplasmic-like appearance. It plays crucial roles in modulating myenteric neuron activity, regulating oxidative stress, and influencing neuroinflammation and neurogenesis. http://purl.obolibrary.org/obo/CL_4047044 type 2 interganglionic glia http://purl.obolibrary.org/obo/CL_4040002 enteroglial cell An enteric glial cell that has an elongated, fibrous morphology with long processes that run parallel to nerve fibers connecting enteric myenteric ganglia. This cell is located in the interganglionic fiber tracts of the enteric nervous system. http://purl.obolibrary.org/obo/CL_4047045 type 3 mucosal glia http://purl.obolibrary.org/obo/CL_4040002 enteroglial cell An enteric glial cell located in the lamina propria of the intestinal mucosa. This cell plays important roles in maintaining gut barrier function, regulating intestinal homeostasis, and mediating interactions between the enteric nervous system and the immune system. http://purl.obolibrary.org/obo/CL_4047047 type I enteric glial cell http://purl.obolibrary.org/obo/CL_4040002 enteroglial cell An enteric glial cell located within the ganglia of the enteric nervous system. This cell is characterized by it’s small somata and short, irregularly branched processes that surround neuronal cell bodies in the myenteric and submucosal ganglia. This cell plays important roles in modulating neuronal activity and neurogenesis in the gastrointestinal tract. http://purl.obolibrary.org/obo/CL_4047048 type 4 muscularis propria glia http://purl.obolibrary.org/obo/CL_4040002 enteroglial cell An enteric glial cell characterized by a small central soma that extends long, thin, bipolar projections. This cell is primarily located along small nerve fibers within the muscle layers of the gastrointestinal tract and is known for its unbranching processes that closely follow these nerve fibers in the muscularis. http://purl.obolibrary.org/obo/CL_4047053 TREM2-positive macrophage http://purl.obolibrary.org/obo/CL_0000235 macrophage A macrophage characterized by high expression of Triggering Receptor Expressed on Myeloid cells 2 (TREM2), found in various tissues including the liver, adipose tissue, bone, gut (Colonna, 2023), and tumor microenvironments, where it is associated with immunosuppressive and anti-inflammatory activity (Colmenares, 2024; Khantakova, 2022). This cell exhibits a distinct gene expression profile in the tumor microenvironment, including overexpression of complement system genes (C1QA, C1QB, C1QC, C3), and SPP1 in both mice and humans (Xiong, 2020; Khantakova, 2022). It is involved in phagocytosis, tissue repair, and modulation of immune responses (Coeho, 2021). http://purl.obolibrary.org/obo/CL_4047054 migratory dendritic cell http://purl.obolibrary.org/obo/CL_0000451 dendritic cell A dendritic cell capable of capturing antigens in peripheral tissues and migrating through blood or lymphatic vessels to secondary lymphoid organs, where it presents processed antigens to T cells. It expresses MHC class II molecules and lacks lineage markers associated with other leukocyte populations, distinguishing it as a member of the dendritic cell lineage. This cell plays a pivotal role in initiating and regulating adaptive immune responses by linking peripheral antigen capture with T cell activation in lymphoid tissues. http://purl.obolibrary.org/obo/CL_4047056 large mucus secreting cholangiocyte http://purl.obolibrary.org/obo/CL_1000488 cholangiocyte A columnar, mucin-producing cholangiocyte that lines large bile ducts, including the hilar bile duct, right and left hepatic bile ducts, and large intrahepatic bile ducts. This cell expresses phosphorylated STAT3 and TFF-3 in humans and mice. http://purl.obolibrary.org/obo/CL_4052039 tuft cell of submandibular gland http://purl.obolibrary.org/obo/CL_0002251 epithelial cell of alimentary canal A tuft cell that is part of the epithelium of the submandibular gland, localized to the striated ducts in mice, pigs, and humans, and to the main excretory ducts in rats. This cell is characterized by chemosensory functions, potential roles in immune regulation, and possible involvement in salivary secretion via acetylcholine release. http://purl.obolibrary.org/obo/CL_4052040 tuft cell of stomach http://purl.obolibrary.org/obo/CL_0002204 tuft cell A tuft cell that is part of the epithelium of the stomach. This cell is characterized by gastric chemosensation and immune regulation through IL-25 secretion, which activates ILC2s to produce IL-13, driving epithelial remodelling and tuft cell expansion. Unlike intestinal tuft cells, which are primarily involved in helminth defense and type 2 immunity, the tuft cell of the stomach is primarily involved in inflammation, metaplasia, and hyperplasia. http://purl.obolibrary.org/obo/CL_4052041 tuft cell of auditory tube http://purl.obolibrary.org/obo/CL_0002491 auditory epithelial cell A tuft cell that is part of the epithelium of the pharyngotympanic (auditory) tube. This chemosensory cell is often positioned near cholinoreceptive sensory nerve fibers, suggesting a role in neuroimmune communication. It detects chemical signals and releases neuropeptides, such as acetylcholine (ACh) and CGRP, which contribute to inflammatory responses that help protect deeper tissues from harmful substances. http://purl.obolibrary.org/obo/CL_4052042 tuft cell of urethra http://purl.obolibrary.org/obo/CL_1000296 epithelial cell of urethra A tuft cell that is part of the epithelium of the urethra. This cell monitors urethral contents by detecting chemical stimuli, such as bitter compounds and sugars. Upon activation, it stimulates sensory nerve fibres and triggers detrusor muscle contraction, likely aiding in pathogen clearance by promoting bladder emptying. http://purl.obolibrary.org/obo/CL_4052045 steroidogenic stromal cell of ovary http://purl.obolibrary.org/obo/CL_0002132 stromal cell of ovary A stromal cell that is part of the ovarian stroma, characterized by its ability to synthesize steroid hormones. http://purl.obolibrary.org/obo/CL_4052046 early luteal cell http://purl.obolibrary.org/obo/CL_0000175 luteal cell A luteal cell that is part of the young, developing corpus luteum. This cell promotes progesterone synthesis, marked by high Parm1 expression in mice (Lan et al., 2024). An early luteal cell is associated with steroidogenesis and cell growth, contributing to early corpus luteum function and maturation. http://purl.obolibrary.org/obo/CL_4052047 late luteal cell http://purl.obolibrary.org/obo/CL_0000175 luteal cell A luteal cell that is part of the older, regressing corpus luteum. This cell exhibits increased expression of genes involved in progesterone metabolism - Akr1c18 in mice (Lan et al., 2024), cell cycle arrest, and apoptosis. A late luteal cell contributes to corpus luteum regression and eventual clearance from the ovary through luteolysis. http://purl.obolibrary.org/obo/CL_4052050 luminal epithelial cell of endometrium http://purl.obolibrary.org/obo/CL_0002149 epithelial cell of uterus An epithelial cell that is part of an endometrium luminal epithelium. http://purl.obolibrary.org/obo/CL_4052051 uterine natural killer cell 1, human http://purl.obolibrary.org/obo/CL_4052028 uterine natural killer cell ​​A uterine natural killer subset that is present in the endometrial lining during the non-pregnant state (Garcia-Alonso et al., 2021) and in the decidua during pregnancy (Vento-Tormo et al., 2018). It expresses the uterine resident marker CD49a and is distinguished from uNK2 and uNK3 by CD39 expression and the absence of CD103 (Whettlock et al., 2022) and CD160 (Marečková et al., 2024). It also expresses higher levels of killer-cell immunoglobulin-like receptors (KIRs) and leukocyte immunoglobulin-like receptor B1 (LILRB1), which facilitate interaction with human leukocyte antigens (HLAs) on extravillous trophoblast cells, promoting immune tolerance and implantation. Enriched in the endometrium post-ovulation (Marečková et al., 2024) and prominent in early pregnancy (Whettlock et al., 2022), uNK1 regulates trophoblast invasion and spiral artery remodeling (Zhang & Wei, 2021). http://purl.obolibrary.org/obo/CL_4052052 uterine natural killer cell 2, human http://purl.obolibrary.org/obo/CL_4052028 uterine natural killer cell A uterine natural killer subset that is present in the endometrial lining during the non-pregnant state (Garcia-Alonso et al., 2021) and in the decidua during pregnancy (Vento-Tormo et al., 2018), peaking in the first trimester. It expresses the uterine resident marker CD49a and is distinguished from uNK1 and uNK3 by the absence of CD39, CD103 (Whettlock et al., 2022), and CD160 (Marečková et al., 2024), with ITGB2 serving as a defining marker (Vento-Tormo et al., 2018). Functionally, it produces more cytokines upon stimulation than uNK1, suggesting a role in immune defense, and secretes XCL1 chemokines, facilitating interactions with maternal dendritic cells and fetal extravillous trophoblasts (Vento-Tormo et al., 2018). http://purl.obolibrary.org/obo/CL_4052053 uterine natural killer cell 3, human http://purl.obolibrary.org/obo/CL_4052028 uterine natural killer cell A uterine natural killer subset found in the endometrial lining during the non-pregnant state (Garcia-Alonso et al., 2021) and in the decidua during pregnancy (Vento-Tormo et al., 2018), becoming the dominant uNK subset late in pregnancy. It expresses the uterine resident marker CD49a and is distinguished from uNK1 and uNK2 by CD160 (Marečková et al., 2024) and CD103 expression, the absence of CD39, and low KIR levels (Whettlock et al., 2022). Resembling intraepithelial ILC1 cells, uNK3 primarily supports uterine immune defense (Huhn et al., 2020) and indirectly influences trophoblast behavior through chemokine secretion, such as CCL5 (Vento-Tormo et al., 2018). http://purl.obolibrary.org/obo/CL_4052055 mature NK T cell, human http://purl.obolibrary.org/obo/CL_0000814 mature NK T cell A mature NK T cell that can be identified by the expression of CD56 in humans. http://purl.obolibrary.org/obo/CL_4070010 gastric mill neuron http://purl.obolibrary.org/obo/CL_0000100 motor neuron A motor neuron that moves the medial tooth forward http://purl.obolibrary.org/obo/CL_4070011 lateral gastric neuron http://purl.obolibrary.org/obo/CL_0000100 motor neuron A motor neuron that closes the lateral teeth. http://purl.obolibrary.org/obo/CL_4070012 inferior cardiac neuron http://purl.obolibrary.org/obo/CL_0000100 motor neuron A motor neuron that controls ventral stomach grooves leading to pyloric filter. http://purl.obolibrary.org/obo/CL_4070013 ventricular dilator motor neuron http://purl.obolibrary.org/obo/CL_0000100 motor neuron A motor neuron that controls ventral stomach grooves leading to pyloric filter. http://purl.obolibrary.org/obo/CL_4070014 pyloric motor neuron http://purl.obolibrary.org/obo/CL_0000100 motor neuron A motor neuron that controls pyloric filter movements; innervates the pyloric muscle. http://purl.obolibrary.org/obo/CL_4070015 pyloric dilator neuron http://purl.obolibrary.org/obo/CL_0000100 motor neuron A motor neuron that controls the cardiopyloric valve. http://purl.obolibrary.org/obo/CL_4070016 anterior burster neuron http://purl.obolibrary.org/obo/CL_0000099 interneuron Pyloric pacemaker neuron that provides feedback to commissural ganglia (CoG) neurons. http://purl.obolibrary.org/obo/CL_4070017 lateral pyloric motor neuron http://purl.obolibrary.org/obo/CL_0000100 motor neuron A motor neuron that controls pyloric filter movements; innervates the lateral pyloric muscle. http://purl.obolibrary.org/obo/CL_4307133 BAM NN_1 Mrc1 border associated macrophage (Mmus) http://purl.obolibrary.org/obo/CL_4301625 border associated macrophage (Mmus) A border associated macrophage of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Mrc1 (Mmus), Pf4 (Mmus). It is distinguished from other BAM NN cells by expression of Mrc1, Pf4. These cells are located in the Medulla, Cerebellum, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5313 BAM NN_1. http://purl.obolibrary.org/obo/CL_4047060 BAG3-positive monocyte http://purl.obolibrary.org/obo/CL_0000576 monocyte A circulating mononuclear phagocyte characterized by the expression of BCL-2-associated athanogene 3 (BAG3) protein, a co-chaperone involved in protein quality control and anti-apoptotic processes. (Fontanella, 2009). It undergoes cellular stress during the differentiation into M2 macrophages and is linked to poor survival rates in multiple cancer types. (Park, 2023) http://purl.obolibrary.org/obo/CL_4301590 Astro-NT NN_2 astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4300358 subcortical astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gja1 (Mmus), A330076C08Rik (Mmus), Itih3 (Mmus), Gria2 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1160 Astro-NT NN_2. http://purl.obolibrary.org/obo/CL_4052060 spinous cell http://purl.obolibrary.org/obo/CL_0000312 keratinocyte A differentiating keratinocyte found in the epidermis and oral epithelium, located in the stratum spinosum, characterized by a spiny appearance due to abundant intercellular desmosomal junctions. http://purl.obolibrary.org/obo/CL_4307049 Astro-TE NN_5 Hs3st3a1 astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301595 Astro-TE NN_5 astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of S1pr1 (Mmus), Thbs4 (Mmus), Hs3st3a1 (Mmus), Sfrp1 (Mmus). It is distinguished from other Astro-TE NN_5 cells by expression of Hs3st3a1, Sfrp1. These cells are located in the Olfactory areas, brain , in or close to the regions: Anterior olfactory nucleus, corpus callosum, body, lateral ventricle, corpus callosum, anterior forceps . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5229 Astro-TE NN_5. http://purl.obolibrary.org/obo/CL_4072009 A12 dopaminergic neuron http://purl.obolibrary.org/obo/CL_0012001 neuron of the forebrain A type of dopaminergic neuron found in the arcuate hypothalamic nucleus, involved in neuroendocrine regulation, metabolic homeostasis and prolactin secretion. http://purl.obolibrary.org/obo/CL_4307114 ABC NN_1 Dapl1 arachnoid barrier cell (Mmus) http://purl.obolibrary.org/obo/CL_4301616 arachnoid barrier cell (Mmus) A arachnoid barrier cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Slc47a1 (Mmus), Dapl1 (Mmus). It is distinguished from other ABC NN cells by expression of Dapl1. These cells are located in the brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5294 ABC NN_1. http://purl.obolibrary.org/obo/CL_4033105 superior cervical ganglion SST neuron http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron A sympathetic neuron that has the soma located in the superior cervical ganglion and expresses the marker somatostatin (SST). http://purl.obolibrary.org/obo/CL_4307037 Astro-NT NN_2 Gm30524 astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301590 Astro-NT NN_2 astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Aqp4 (Mmus), A330076C08Rik (Mmus), Fbln5 (Mmus), Mdga2 (Mmus). It is distinguished from other Astro-NT NN_2 cells by expression of Gm30524. These cells are located in the Medulla, Cerebellum, brain , in or close to the regions: Ventral cochlear nucleus, arbor vitae . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5217 Astro-NT NN_2. http://purl.obolibrary.org/obo/CL_4033152 jugular ganglion TRPV1 neuron http://purl.obolibrary.org/obo/CL_0000101 sensory neuron A sensory neuron that has the soma located in the jugular ganglion and expresses the marker transient receptor potential vanilloid 1 (TRPV1). http://purl.obolibrary.org/obo/CL_4301585 CB Granule Glut_2 cerebellar granule cell (Mmus) http://purl.obolibrary.org/obo/CL_4300354 cerebellar granule cell (Mmus) A cerebellar granule cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gabra6 (Mmus), Gap43 (Mmus), Rab37 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1155 CB Granule Glut_2. http://purl.obolibrary.org/obo/CL_4307110 OEC NN_1 Gdpd4 olfactory ensheathing cell (Mmus) http://purl.obolibrary.org/obo/CL_4301615 olfactory ensheathing cell (Mmus) A olfactory ensheathing cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Apod (Mmus), Aqp1 (Mmus), Cldn5 (Mmus). It is distinguished from other OEC cells by expression of Gdpd4, Cldn5. These cells are located in the brain , in or close to the regions: olfactory nerve layer of main olfactory bulb . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5290 OEC NN_1. http://purl.obolibrary.org/obo/CL_4301603 Tanycyte NN_2 tanycyte (Mmus) http://purl.obolibrary.org/obo/CL_4300362 tanycyte (Mmus) A tanycyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gpr50 (Mmus), Ccdc170 (Mmus), Nkx2-4 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1173 Tanycyte NN_2. http://purl.obolibrary.org/obo/CL_4301598 Astro-OLF NN_3 astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4300360 olfactory areas astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Ednrb (Mmus), Hs3st3a1 (Mmus), C230072F16Rik (Mmus), Gria2 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1168 Astro-OLF NN_3. http://purl.obolibrary.org/obo/CL_4306992 DCO Il22 Gly-Gaba_2 cerebellar neuron (Mmus) http://purl.obolibrary.org/obo/CL_4300348 DCO Il22 Gly-Gaba cerebellar neuron (Mmus) A cerebellar neuron of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Il22 (Mmus), Edaradd (Mmus). It is distinguished from other DCO Il22 Gly-Gaba cells by expression of Ppp1r17. It is GABAergic and glycinergic (inferred from expression of Slc32a1, Hdc, Slc6a5, Gad2, Gad1). These cells are located in the Medulla, Cerebellum, brain , in or close to the regions: Paraflocculus, arbor vitae, Dorsal cochlear nucleus . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5172 DCO Il22 Gly-Gaba_2. http://purl.obolibrary.org/obo/CL_4072005 A8 dopaminergic neuron http://purl.obolibrary.org/obo/CL_2000097 midbrain dopaminergic neuron A type of midbrain dopaminergic neuron localized in the retrorubral field which projects to limbic and cortical regions involved in emotion, motivation, and reward. http://purl.obolibrary.org/obo/GO_0160276 negative regulation of beige fat cell differentiation http://purl.obolibrary.org/obo/GO_0045599 negative regulation of fat cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of beige fat cell differentiation. http://purl.obolibrary.org/obo/CL_4301625 border associated macrophage (Mmus) http://purl.obolibrary.org/obo/CL_4042003 border associated macrophage A border associated macrophage of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Mrc1 (Mmus), Maf (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1195 BAM NN_1. http://purl.obolibrary.org/obo/UBERON_0016514 cavity of left ventricle http://purl.obolibrary.org/obo/UBERON_0035763 cavity of cardiac chamber Luminal space of the left ventricle of the heart. http://purl.obolibrary.org/obo/CL_0002323 amniocyte http://purl.obolibrary.org/obo/CL_0000349 extraembryonic cell A cell of a fetus which is suspended in the amniotic fluid. Amniocytes are considered to arise from several tissues including fetal skin, the fetal urinary tract, umbilical cord, and the inner amniotic surface. http://purl.obolibrary.org/obo/UBERON_0005872 1st arch pharyngeal cleft http://purl.obolibrary.org/obo/UBERON_0005879 pharyngeal cleft A groove that is situated between the 1st and 2nd pharyngeal arch. http://purl.obolibrary.org/obo/UBERON_0016511 lamina propria of fundus of stomach http://purl.obolibrary.org/obo/UBERON_8600138 stomach lamina propria A lamina propria that is part of a mucosa of fundus of stomach. http://purl.obolibrary.org/obo/UBERON_0007831 pectoral girdle skeleton http://purl.obolibrary.org/obo/UBERON_0010719 girdle skeleton A subdivision of a limb or fin skeleton consisting of bones which connects the upper limb or fin to the axial skeleton on each side. It consists of the clavicle and scapula in humans and, in those species with three bones in the pectoral girdle, the coracoid. Some mammalian species (e.g. the dog and the horse) have only the scapula. In humans, the only joints between the shoulder girdle and axial skeleton are the sternoclavicular joints on each side. No joint exists between each scapula and the rib cage; instead the muscular connection between the two permits relatively great mobility of the shoulder girdle in relation to the pelvic girdle. In those species having only the scapula, no joint exists between the forelimb and the thorax, the only attachment being muscular[WP]. Examples: There are only two instances, right and left pectoral girdle skeletons. http://purl.obolibrary.org/obo/GO_0120006 regulation of glutamatergic neuron differentiation http://purl.obolibrary.org/obo/GO_0045664 regulation of neuron differentiation Any process that modulates the frequency, rate or extent of glutamatergic neuron differentiation. http://purl.obolibrary.org/obo/GO_0120007 negative regulation of glutamatergic neuron differentiation http://purl.obolibrary.org/obo/GO_0045665 negative regulation of neuron differentiation Any process that stops, prevents or reduces the frequency, rate or extent of glutamatergic neuron differentiation. http://purl.obolibrary.org/obo/GO_0120008 positive regulation of glutamatergic neuron differentiation http://purl.obolibrary.org/obo/GO_0045666 positive regulation of neuron differentiation Any process that activates or increases the frequency, rate or extent of glutamatergic neuron differentiation. http://purl.obolibrary.org/obo/GO_1905962 glutamatergic neuron differentiation http://purl.obolibrary.org/obo/GO_0030182 neuron differentiation The process in which a relatively unspecialized cell acquires the specialized features of a glutamatergic neuron. http://purl.obolibrary.org/obo/GO_0110077 vesicle-mediated intercellular transport http://purl.obolibrary.org/obo/GO_0010496 intercellular transport A cellular transport process in which transported substances are moved in extracellular vesicles between cells; transported substances are enclosed in the vesicle lumen or located in the extracellular vesicle membrane. http://purl.obolibrary.org/obo/GO_0110079 regulation of placenta blood vessel development http://purl.obolibrary.org/obo/GO_1901342 regulation of vasculature development Any process that modulates the frequency, rate or extent of placenta blood vessel development. http://purl.obolibrary.org/obo/GO_0110080 positive regulation of placenta blood vessel development http://purl.obolibrary.org/obo/GO_0051094 positive regulation of developmental process Any process that activates or increases the frequency, rate or extent of placenta blood vessel development. http://purl.obolibrary.org/obo/GO_0110081 negative regulation of placenta blood vessel development http://purl.obolibrary.org/obo/GO_0051093 negative regulation of developmental process Any process that stops, prevents or reduces the frequency, rate or extent of placenta blood vessel development. http://purl.obolibrary.org/obo/GO_0140157 ammonium import across plasma membrane http://purl.obolibrary.org/obo/GO_0072488 ammonium transmembrane transport The directed movement of an ammonium ion from outside of a cell, across the plasma membrane and into the cytosol. http://purl.obolibrary.org/obo/GO_0150031 regulation of protein localization to lysosome http://purl.obolibrary.org/obo/GO_0032880 regulation of protein localization Any process that modulates the frequency, rate or extent of protein localization to lysosome. http://purl.obolibrary.org/obo/GO_0150032 positive regulation of protein localization to lysosome http://purl.obolibrary.org/obo/GO_1903829 positive regulation of protein localization Any process that activates or increases the frequency, rate or extent of protein localization to lysosome. http://purl.obolibrary.org/obo/GO_0150033 negative regulation of protein localization to lysosome http://purl.obolibrary.org/obo/GO_1903828 negative regulation of protein localization Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to lysosome. http://purl.obolibrary.org/obo/GO_0061983 meiosis II cell cycle process http://purl.obolibrary.org/obo/GO_1903046 meiotic cell cycle process A process that coontributes to the second meiotic division. The second meiotic division separates chromatids resulting in a haploid number of chromosomes. http://purl.obolibrary.org/obo/GO_0150077 regulation of neuroinflammatory response http://purl.obolibrary.org/obo/GO_0050727 regulation of inflammatory response Any process that modulates the frequency, rate or extent of neuroinflammatory response. http://purl.obolibrary.org/obo/GO_0120316 sperm flagellum assembly http://purl.obolibrary.org/obo/GO_0044458 motile cilium assembly The assembly and organization of the sperm flagellum, the microtubule-based axoneme and associated structures that are part of a sperm flagellum (or cilium). http://purl.obolibrary.org/obo/CL_0011029 cnidocyte http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell An explosive cell containing one giant secretory organelle called a cnidocyst (also known as a cnida (plural cnidae) or nematocyst) that contains a toxin responsible for the stings delivered by a cnidarian to other organisms. Cnidae are used to capture prey and as a defense against predators. The presence of cnidocytes defines the phylum Cnidaria (corals, sea anemones, hydrae, jellyfish, etc.). http://purl.obolibrary.org/obo/CL_4023107 reticulospinal neuron http://purl.obolibrary.org/obo/CL_2000029 central nervous system neuron A neuron with soma location in the reticular formation with axons that extend into the spinal cord such. Reticulospinal neuron activity can lead to a variety of motor behaviors. http://purl.obolibrary.org/obo/CL_0009038 colon macrophage http://purl.obolibrary.org/obo/CL_0000235 macrophage A macrophage that is located in the colon. http://purl.obolibrary.org/obo/CL_0009060 marginal zone B cell of lymph node http://purl.obolibrary.org/obo/CL_0000785 mature B cell A mature B cell located in the marginal zone of the lymph node. http://purl.obolibrary.org/obo/PATO_0070060 quality of interaction of a substance with electromagnetic radiation http://purl.obolibrary.org/obo/PATO_0002198 quality of a substance A quality of a substance on which or through which electromagnetic radiation impinges or traverses with respect to radiation. This substance quality changes the quality of the incident radiation with respect to any of: intensity, direction, scatter and wavelength. http://purl.obolibrary.org/obo/CL_4030003 interstitial cell of thymus http://purl.obolibrary.org/obo/CL_4030001 stromal cell of thymus A cell that makes up the loose connective tissue of the thymus. http://purl.obolibrary.org/obo/CL_0003026 retinal ganglion cell D1 http://purl.obolibrary.org/obo/CL_0003001 bistratified retinal ganglion cell A bistratified retinal ganglion cell that has a small dendrite fields with a sparse dendrite arbor terminating in S2 and S3. http://purl.obolibrary.org/obo/CL_0003044 M11 retinal ganglion cell http://purl.obolibrary.org/obo/CL_0003001 bistratified retinal ganglion cell A bistratified ganglion cell with small, dense dendritic fields that terminate in S1 and S3. http://purl.obolibrary.org/obo/CL_0004161 510 nm-cone http://purl.obolibrary.org/obo/CL_0003049 M cone cell A cone whose sensitivity measurements have an average spectral peak of 510 nm. These cones are described in rat. http://purl.obolibrary.org/obo/PATO_0070062 bistratified dendrite cell morphology http://purl.obolibrary.org/obo/PATO_0010006 cell morphology A cell morphology that inheres in neurons with dendrites that stratify at two and only two locations. http://purl.obolibrary.org/obo/CL_4023062 dentate gyrus neuron http://purl.obolibrary.org/obo/CL_0002608 hippocampal neuron A neuron with its soma located in the dentate gyrus of the hippocampus. http://purl.obolibrary.org/obo/CL_4023059 committed oligodendrocyte precursor http://purl.obolibrary.org/obo/CL_0000123 neuron associated cell (sensu Vertebrata) An oligodendrocyte precursor cell that is committed to differentiate. http://purl.obolibrary.org/obo/UBERON_8600006 visceral striated muscle tissue http://purl.obolibrary.org/obo/UBERON_8600004 visceral muscle tissue A striated muscle tissue that is associated with soft internal organs (viscera). http://purl.obolibrary.org/obo/CL_4030038 CD24-positive, CD-133-positive, vimentin-positive proximal tubular cell http://purl.obolibrary.org/obo/CL_0002306 epithelial cell of proximal tubule A CD24-positive, CD-133-positive, vimentin-positive cell found scattered throughout a renal proximal tubule and that may participate in tubular regeneration. Compared to other proximal tubular cell types, this cell contains less cytoplasm, fewer mitochondria and no brush border. http://purl.obolibrary.org/obo/CL_4033015 retinal astrocyte http://purl.obolibrary.org/obo/CL_0009004 retinal cell A star-shaped glial cell that is part of some retina. This cell links neurons to blood vessels and may provide structural and physiological support to optic nerve head axons. http://purl.obolibrary.org/obo/CL_4033027 diffuse bipolar 1 cell http://purl.obolibrary.org/obo/CL_0000750 OFF-bipolar cell An OFF diffuse bipolar cell that makes synaptic contact with both L/M and S-cone photoreceptors and only minimal contact with rod photoreceptors. http://purl.obolibrary.org/obo/CL_4033028 diffuse bipolar 2 cell http://purl.obolibrary.org/obo/CL_0000750 OFF-bipolar cell An OFF diffuse bipolar cell that predominantly connects to ON parasol cells and lateral amacrine cells. This cell contains a large number of synaptic ribbons and a small axon arbor area. http://purl.obolibrary.org/obo/CL_4033029 diffuse bipolar 3a cell http://purl.obolibrary.org/obo/CL_0000750 OFF-bipolar cell An OFF calbindin-positive bipolar cell that has a large dendritic field and stratifies narrowly close to the middle of the inner plexiform layer. Its axon terminal is characterized by regularly branching and varicose processes resembling beads on a string. Most of DB3a contacts with cones are triad-associated. http://purl.obolibrary.org/obo/CL_4033030 diffuse bipolar 3b cell http://purl.obolibrary.org/obo/CL_0000750 OFF-bipolar cell An OFF calbindin-negative bipolar cell that has a large dendritic field and stratifies narrowly close to the middle of the inner plexiform layer. Its axon terminal is characterized by regularly branching and varicose processes resembling beads on a string. Most of DB3b contacts with cones are non-triad-associated. http://purl.obolibrary.org/obo/CL_4033031 diffuse bipolar 4 cell http://purl.obolibrary.org/obo/CL_0000749 ON-bipolar cell An ON diffuse bipolar cell that predominantly connects to ON parasol cells and lateral amacrine cells. http://purl.obolibrary.org/obo/CL_4033032 diffuse bipolar 6 cell http://purl.obolibrary.org/obo/CL_0000749 ON-bipolar cell An ON diffuse bipolar cell that has a large dendritic field and large axon terminals, which show little or no overlap. This cell predominantly connects to narrow thorny ganglion cells. http://purl.obolibrary.org/obo/CL_4033033 flat midget bipolar cell http://purl.obolibrary.org/obo/CL_0000750 OFF-bipolar cell An OFF bipolar cell with a small dendritic tree that provides most of the triad-associated basal (flat) contacts at cone pedicles. http://purl.obolibrary.org/obo/CL_4033034 invaginating midget bipolar cell http://purl.obolibrary.org/obo/CL_0000749 ON-bipolar cell An ON bipolar cell with a small dendritic tree that forms most of the central (invaginating) elements opposite the synaptic ribbon at the cone triad. http://purl.obolibrary.org/obo/CL_4033035 giant bipolar cell http://purl.obolibrary.org/obo/CL_0000749 ON-bipolar cell An ON bipolar cell that has large dendritic and axonal fields. http://purl.obolibrary.org/obo/CL_4033036 OFFx cell http://purl.obolibrary.org/obo/CL_0000750 OFF-bipolar cell An OFF bipolar cell that is fovea-specific and expresses FEZF1, NXPH1 and NXPH2. http://purl.obolibrary.org/obo/CL_4040000 glial restricted tripotential precursor cell http://purl.obolibrary.org/obo/CL_0011115 precursor cell A glial precursor cell that generates oligodendrocytes and type-1 and type-2 astrocytes. It has been shown in some mammals that this cell type may express A2B5, nestin, FGFR-1, FGFR-2, FGFR-3, PLP, and DM-20 antigens. Unlike oligodendrocyte precursor cell, it does not initially express PDGFR-alpha and can differentiate into both type-1 and type-2 astrocytes. http://purl.obolibrary.org/obo/CL_4040001 chorionic girdle cell http://purl.obolibrary.org/obo/CL_0011101 chorionic trophoblast cell A horse-specific, highly invasive trophoblast cell that invades the endometrium where it forms endometrial cups. http://purl.obolibrary.org/obo/CL_4040002 enteroglial cell http://purl.obolibrary.org/obo/CL_0000125 glial cell Glial cell that provides support to the enteric nervous system. It is involved in enteric neurotransmission, in maintaining the integrity of the mucosal barrier of the gut and serves as a link between the nervous and immune systems of the gut. In enteric nerve strands, glial processes ensheath multiaxonal bundles which distinguishes enteric glia from all other peripheral glia. Ultrastructurally, the most conspicuous trait of an enteroglial cell is the presence of 10 nm filaments, which criss-cross the cell body, form axial bundles in the processes and appear to firmly anchor the cells to the ganglionic surfaces. Similar to astrocytes, their main constituent is glial fibrillary acidic protein (GFAP). http://purl.obolibrary.org/obo/UBERON_8910001 stomatogastric ganglion http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision The stomatogastric ganglion (STG) consists of about 30 neurons that form two central pattern generator circuits in crustaceans. STG neurons have large soma (~50-100 um) and have complex branches. The STG contains the motor neurons that innervate the striated muscles that move the gastric mill and pyloric regions of the stomach. http://purl.obolibrary.org/obo/UBERON_0018143 transverse process of cervical vertebra http://purl.obolibrary.org/obo/UBERON_0001077 transverse process of vertebra A transverse process that is part of a cervical vertebra. http://purl.obolibrary.org/obo/UBERON_0003071 eye primordium http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure Portion of tissue that is part of the anterior neural keel and will form the optic vesicle[ZFA]. A paired ectodermal placode that becomes invaginated to form the embryonic lens vesicles. http://purl.obolibrary.org/obo/CL_0002583 subcutaneous preadipocyte http://purl.obolibrary.org/obo/CL_0002334 preadipocyte A preadipocyte that is part of subcutaneous tissue. http://purl.obolibrary.org/obo/GO_0099156 cell-cell signaling via exosome http://purl.obolibrary.org/obo/GO_0007267 cell-cell signaling Cell-cell signaling in which the ligand is carried between cells by an exosome. http://purl.obolibrary.org/obo/GO_0099157 trans-synaptic signaling via exosome http://purl.obolibrary.org/obo/GO_0099537 trans-synaptic signaling Transynaptic signaling in which the ligand is carried across the synapse by an exosome. http://purl.obolibrary.org/obo/GO_0099177 regulation of trans-synaptic signaling http://purl.obolibrary.org/obo/GO_0023051 regulation of signaling Any process that modulates the frequency, rate or extent of trans-synaptic signaling. http://purl.obolibrary.org/obo/GO_0099163 synaptic signaling by nitric oxide http://purl.obolibrary.org/obo/GO_0099536 synaptic signaling Cell-cell signaling to or from a synapse, mediated by nitric oxide. http://purl.obolibrary.org/obo/GO_0099173 postsynapse organization http://purl.obolibrary.org/obo/GO_0016043 cellular component organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a postsynapse. http://purl.obolibrary.org/obo/GO_0099174 regulation of presynapse organization http://purl.obolibrary.org/obo/GO_0050807 regulation of synapse organization Any process that modulates the physical form of a presynapse. http://purl.obolibrary.org/obo/GO_0140141 mitochondrial potassium ion transmembrane transport http://purl.obolibrary.org/obo/GO_0071805 potassium ion transmembrane transport The process in which a potassium ion is transported across a mitochondrial membrane, into or out of the mitochondrion. http://purl.obolibrary.org/obo/GO_0099185 postsynaptic intermediate filament cytoskeleton organization http://purl.obolibrary.org/obo/GO_0045104 intermediate filament cytoskeleton organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprised of intermediate filament and their associated proteins in the postsynaptic cytoskeleton. http://purl.obolibrary.org/obo/GO_0099187 presynaptic cytoskeleton organization http://purl.obolibrary.org/obo/GO_0007010 cytoskeleton organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures and their associated proteins in the presynaptic cytoskeleton. http://purl.obolibrary.org/obo/GO_0099188 postsynaptic cytoskeleton organization http://purl.obolibrary.org/obo/GO_0007010 cytoskeleton organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising cytoskeletal filaments and their associated proteins in the postsynaptic cytoskeleton. http://purl.obolibrary.org/obo/GO_0140146 calcium ion import into vacuole http://purl.obolibrary.org/obo/GO_0034486 vacuolar transmembrane transport The directed movement of calcium cations into the vacuole across the vacuolar membrane. http://purl.obolibrary.org/obo/GO_0140253 cell-cell fusion http://purl.obolibrary.org/obo/GO_0009987 cellular process A cellular process in which two or more cells combine together, their plasma membrane fusing, producing a single cell. In some cases, nuclei fuse, producing a polyploid cell, while in other cases, nuclei remain separate, producing a syncytium. http://purl.obolibrary.org/obo/PR_000044669 P2X receptor protein http://purl.obolibrary.org/obo/PR_000044671 ligand-gated ion channel protein A ligand-gated ion channel protein that is a translation product of the human P2RX1, P2RX2, P2RX3, P2RX4, P2RX5, P2RX6, or P2RX7 genes, 1:1 orthologs thereof, or a semi-ortholog thereof. http://purl.obolibrary.org/obo/CL_4023056 vascular leptomeningeal cell (Mmus) http://purl.obolibrary.org/obo/CL_4023051 vascular leptomeningeal cell A type of mouse mesothelial fibroblast that is derived from the neural crest, is localized on blood vessels, and is a key component of the pia and arachnoid membranes surrounding the brain. http://purl.obolibrary.org/obo/CL_0009027 transit amplifying cell of appendix http://purl.obolibrary.org/obo/CL_0002253 epithelial cell of large intestine A transit amplifying cell that is part of a crypt of Lieberkuhn of large intestine. http://purl.obolibrary.org/obo/CL_4023052 Betz upper motor neuron http://purl.obolibrary.org/obo/CL_0008049 Betz cell A Betz cell that synapses with lower motor neurons directly. http://purl.obolibrary.org/obo/CL_4023093 stellate pyramidal neuron http://purl.obolibrary.org/obo/CL_0000598 pyramidal neuron A pyramidal neuron which lacks a tuft formation but extends small radial distances forming a star-like shape. http://purl.obolibrary.org/obo/CL_0009039 colon goblet cell http://purl.obolibrary.org/obo/CL_1000320 large intestine goblet cell A goblet cell that is located in the colon. http://purl.obolibrary.org/obo/CL_0009046 T cell of medullary sinus of lymph node http://purl.obolibrary.org/obo/CL_0000084 T cell A T cell found in the lymph node medullary sinus. http://purl.obolibrary.org/obo/CL_0009047 macrophage of medullary sinus of lymph node http://purl.obolibrary.org/obo/CL_0000235 macrophage A macrophage found in the medullary sinus of the lymph node. http://purl.obolibrary.org/obo/CL_0009048 anorectum macrophage http://purl.obolibrary.org/obo/CL_0000235 macrophage A macrophage that is located in the anorectum. http://purl.obolibrary.org/obo/CL_0009050 B cell of anorectum http://purl.obolibrary.org/obo/CL_0000236 B cell A B cell that is located in the anorectum. http://purl.obolibrary.org/obo/CL_0009051 T cell of anorectum http://purl.obolibrary.org/obo/CL_0000084 T cell A T cell that is located in the anorectum. http://purl.obolibrary.org/obo/CL_0009053 stromal cell of anorectum lamina propria http://purl.obolibrary.org/obo/CL_0009021 stromal cell of lamina propria of large intestine A stromal cell found in the lamina propria of the anorectum. http://purl.obolibrary.org/obo/CL_0009056 transit amplifying cell of anorectum http://purl.obolibrary.org/obo/CL_0002253 epithelial cell of large intestine A transit amplifying cell that is located in the anorectum. http://purl.obolibrary.org/obo/CL_0009065 tuft cell of anorectum http://purl.obolibrary.org/obo/CL_0002203 tuft cell of large intestine An intestinal tuft cell that is located in the anorectum. http://purl.obolibrary.org/obo/CL_0009066 stratified squamous epithelial cell of anal canal http://purl.obolibrary.org/obo/CL_0002253 epithelial cell of large intestine A stratified squamous epithelial cell that is part of the anal canal. http://purl.obolibrary.org/obo/UBERON_8410011 myenteric nerve plexus of appendix http://purl.obolibrary.org/obo/UBERON_0002439 myenteric nerve plexus Myenteric nerve plexus that is located in the vermiform appendix. http://purl.obolibrary.org/obo/UBERON_8410031 muscularis mucosae of appendix http://purl.obolibrary.org/obo/UBERON_0001239 muscularis mucosae of large intestine A muscularis mucosa that is part of a vermiform appendix. http://purl.obolibrary.org/obo/UBERON_8410046 appendix smooth muscle circular layer http://purl.obolibrary.org/obo/UBERON_0012368 circular muscle layer of muscular coat A circular muscle layer of muscular coat that is part of a vermiform appendix smooth muscle. http://purl.obolibrary.org/obo/UBERON_8410047 appendix smooth muscle longitudinal layer http://purl.obolibrary.org/obo/UBERON_0012369 longitudinal muscle layer of muscular coat A longitudinal muscle layer of muscular coat that is part of a vermiform appendix smooth muscle. http://purl.obolibrary.org/obo/UBERON_8410052 lymph node germinal center light zone http://purl.obolibrary.org/obo/UBERON_0001744 lymphoid tissue Lymph node germinal centers contain two microenvironments: the light zone and the dark zone. The light zone is sparsely populated with B cells and includes additional cell types such as follicular dendritic cells, lymph node tingible macrophages and T follicular helper cells. http://purl.obolibrary.org/obo/UBERON_8410053 lymph node germinal center dark zone http://purl.obolibrary.org/obo/UBERON_0001744 lymphoid tissue Lymph node germinal centers contain two microenvironments: the light zone and the dark zone. The dark zone is densely populated with B cell blasts and reticular cells. http://purl.obolibrary.org/obo/CL_0009113 T follicular regulatory cell http://purl.obolibrary.org/obo/CL_0000815 regulatory T cell A regulatory T cell present in the B cell follicles and germinal centers of lymphoid tissues. In humans, it is CXCR5+. http://purl.obolibrary.org/obo/CL_4029002 germline-derived nurse cell http://purl.obolibrary.org/obo/CL_4029001 gamete-nursing cell A gamete-nursing cell that derives from a germline cell (del Pino, 2021). http://purl.obolibrary.org/obo/CL_0003047 M14 retinal ganglion cell http://purl.obolibrary.org/obo/CL_0003001 bistratified retinal ganglion cell A bistratifed retinal ganglion cell that has small, symmetric dendritic fields that terminate in S1 and S4-S5. http://purl.obolibrary.org/obo/CL_0004250 bistratified retinal amacrine cell http://purl.obolibrary.org/obo/CL_0004247 bistratified cell An amicrine that stratifies dendrites at two and only two locations. http://purl.obolibrary.org/obo/CL_0003010 G7 retinal ganglion cell http://purl.obolibrary.org/obo/CL_0003001 bistratified retinal ganglion cell A bistratified retinal ganglion cell that has a dendrite field that terminates in sublaminar layer S2 and a second dendrite field that terminates in sublaminar layer S4. http://purl.obolibrary.org/obo/CL_4030029 blood lymphocyte http://purl.obolibrary.org/obo/CL_2000001 peripheral blood mononuclear cell A lymphocyte located in blood. http://purl.obolibrary.org/obo/CL_0003003 G2 retinal ganglion cell http://purl.obolibrary.org/obo/CL_0000740 retinal ganglion cell A mono-stratified retinal ganglion cell that has a small dendritic field and a sparse dendritic arbor with post sympatic terminals in sublaminar layer S3. http://purl.obolibrary.org/obo/CL_0004222 flag B amacrine cell http://purl.obolibrary.org/obo/CL_4030028 glycinergic amacrine cell A flag amacrine cell with post-synaptic terminals in S3, S4, and S5. This cell type releases the neurotransmitter glycine. http://purl.obolibrary.org/obo/CL_0004232 starburst amacrine cell http://purl.obolibrary.org/obo/CL_0008061 GABA-Chol neuron An amacrine cell with a flat dendritic arbor and a medium dendritic field. Starburst amacrine cells have post-synaptic terminals in S2. This cell type releases the neurotransmitters gamma-aminobutyric acid (GABA) and acetylcholine. http://purl.obolibrary.org/obo/CL_0003007 G4-OFF retinal ganglion cell http://purl.obolibrary.org/obo/CL_0003005 G4 retinal ganglion cell A G4 retinal ganglion cell that has post sympatic terminals in sublaminar layers S2 and S3 and is depolarized by decreased illumination of their receptive field center http://purl.obolibrary.org/obo/CL_0004224 AB diffuse-2 amacrine cell http://purl.obolibrary.org/obo/CL_4030028 glycinergic amacrine cell A broadly stratifying amacrine cell that has a small dendritic field and post-synaptic terminals in S2 and S3. This cell type releases the neurotransmitter glycine. http://purl.obolibrary.org/obo/CL_0004213 type 3a cone bipolar cell http://purl.obolibrary.org/obo/CL_0000755 type 3 cone bipolar cell (sensu Mus) A type of type 3 cone bipolar cell with distinctive curly dendrites. http://purl.obolibrary.org/obo/CL_0003028 M1 retinal ganglion cell http://purl.obolibrary.org/obo/CL_0000740 retinal ganglion cell A monostratified retinal ganglion cell that has a small dendrite field with a dense dendrite arbor with post synaptic terminals in sublaminer layer S4. http://purl.obolibrary.org/obo/CL_0004229 A2-like amacrine cell http://purl.obolibrary.org/obo/CL_0004251 narrow field retinal amacrine cell A bistratified amacrine cell with a small dendritic field that has dendrite stratification in S2, and in S3 and S4. http://purl.obolibrary.org/obo/CL_0003009 G6 retinal ganglion cell http://purl.obolibrary.org/obo/CL_0000740 retinal ganglion cell A mono-stratified retinal ganglion cell that has a medium dendritic field and a sparse dendritic arbor with post sympatic terminals in sublaminar layer S4 and S5. http://purl.obolibrary.org/obo/CL_0003014 G11 retinal ganglion cell http://purl.obolibrary.org/obo/CL_0000740 retinal ganglion cell A mono-stratified retinal ganglion cell that has a large dendritic field, a medium dendritic arbor, and a medium length secondary dendrite shaft. http://purl.obolibrary.org/obo/CL_0004226 monostratified amacrine cell http://purl.obolibrary.org/obo/CL_0004246 monostratified cell An amacrine cell with a small dendritic field with post-synaptic terminals in S3 and S4. http://purl.obolibrary.org/obo/CL_0004001 local interneuron http://purl.obolibrary.org/obo/CL_0000099 interneuron An interneuron whose axon stays entirely within the gray matter region where the cell body resides. http://purl.obolibrary.org/obo/CL_0003048 L cone cell http://purl.obolibrary.org/obo/CL_0000573 retinal cone cell A cone cell that detects long wavelength light. Exact peak of spectra detected differs between species. In humans, spectra peaks at 564-580 nm. http://purl.obolibrary.org/obo/CL_0004116 retinal ganglion cell C http://purl.obolibrary.org/obo/CL_0000740 retinal ganglion cell A retinal ganglion with cell medium cell bodies and medium to large dendritic fields. http://purl.obolibrary.org/obo/CL_0004162 360 nm-cone http://purl.obolibrary.org/obo/CL_0003051 UV cone cell A cone whose sensitivity measurements have an average spectral peak of 358.2 nm. These cones are described in rat. http://purl.obolibrary.org/obo/CL_4023057 cerebellar inhibitory GABAergic interneuron http://purl.obolibrary.org/obo/CL_1001611 cerebellar neuron A GABAergic interneuron whose soma is located in the cerebellar cortex. http://purl.obolibrary.org/obo/CL_4023060 hippocampal CA1-3 neuron http://purl.obolibrary.org/obo/CL_0002608 hippocampal neuron A neuron that has its soma located in CA1-3 of the hippocampus. http://purl.obolibrary.org/obo/CL_4023063 medial ganglionic eminence derived interneuron http://purl.obolibrary.org/obo/CL_0000099 interneuron An interneuron that is derived from the medial ganglionic eminence. In mice and humans, it expresses LHX6 and SOX6. http://purl.obolibrary.org/obo/UBERON_8480025 skin of clavicle region http://purl.obolibrary.org/obo/UBERON_0000014 zone of skin A zone of skin that is above the clavicle zone in the pectoral girdle region. http://purl.obolibrary.org/obo/CL_4033002 neuroendocrine cell of epithelium of crypt of Lieberkuhn http://purl.obolibrary.org/obo/CL_1001516 intestinal enteroendocrine cell A(n) neuroendocrine cell that is part of a(n) epithelium of crypt of Lieberkuhn. http://purl.obolibrary.org/obo/UBERON_8850000 lumen of pulmonary alveolus http://purl.obolibrary.org/obo/UBERON_0002553 anatomical cavity An anatomical cavity that is part of the alveolus of the lung http://purl.obolibrary.org/obo/CL_4033068 cycling B cell http://purl.obolibrary.org/obo/CL_0000236 B cell A(n) B cell that is cycling. http://purl.obolibrary.org/obo/CL_4033069 cycling T cell http://purl.obolibrary.org/obo/CL_0000084 T cell A(n) T cell that is cycling. http://purl.obolibrary.org/obo/CL_4033070 cycling dendritic cell http://purl.obolibrary.org/obo/CL_4033078 cycling mononuclear phagocyte A(n) dendritic cell that is cycling. http://purl.obolibrary.org/obo/CL_4033071 cycling natural killer cell http://purl.obolibrary.org/obo/CL_0000623 natural killer cell A(n) natural killer cell that is cycling. http://purl.obolibrary.org/obo/CL_4033072 cycling gamma-delta T cell http://purl.obolibrary.org/obo/CL_4033069 cycling T cell A(n) gamma-delta T cell that is cycling. http://purl.obolibrary.org/obo/CL_4033073 cycling monocyte http://purl.obolibrary.org/obo/CL_4033081 cycling myeloid cell A(n) monocyte that is cycling. http://purl.obolibrary.org/obo/CL_4033074 cycling CD8-positive, alpha-beta T cell http://purl.obolibrary.org/obo/CL_4033069 cycling T cell A(n) CD8-positive, alpha-beta T cell that is cycling. http://purl.obolibrary.org/obo/CL_4033075 cycling CD4-positive, alpha-beta T cell http://purl.obolibrary.org/obo/CL_4033069 cycling T cell A(n) CD4-positive, alpha-beta T cell that is cycling. http://purl.obolibrary.org/obo/CL_4033076 cycling macrophage http://purl.obolibrary.org/obo/CL_4033081 cycling myeloid cell A(n) macrophage that is cycling. http://purl.obolibrary.org/obo/CL_4033077 cycling alveolar macrophage http://purl.obolibrary.org/obo/CL_4033076 cycling macrophage A(n) alveolar macrophage that is cycling. http://purl.obolibrary.org/obo/CL_4033078 cycling mononuclear phagocyte http://purl.obolibrary.org/obo/CL_0000113 mononuclear phagocyte A(n) mononuclear phagocyte that is cycling. http://purl.obolibrary.org/obo/CL_4033079 cycling endothelial cell of lymphatic vessel http://purl.obolibrary.org/obo/CL_0002138 endothelial cell of lymphatic vessel A(n) endothelial cell of lymphatic vessel that is cycling. http://purl.obolibrary.org/obo/CL_4033080 cycling pulmonary alveolar type 2 cell http://purl.obolibrary.org/obo/CL_0002063 pulmonary alveolar type 2 cell A(n) pulmonary alveolar type 2 cell that is cycling. http://purl.obolibrary.org/obo/CL_4033081 cycling myeloid cell http://purl.obolibrary.org/obo/CL_0000763 myeloid cell A(n) myeloid cell that is cycling. http://purl.obolibrary.org/obo/CL_4033082 cycling basal cell http://purl.obolibrary.org/obo/CL_0000646 basal cell A(n) basal cell that is cycling. http://purl.obolibrary.org/obo/CL_4042014 spiny VIP neuron http://purl.obolibrary.org/obo/CL_4023016 VIP GABAergic interneuron A VIP GABAergic cortical interneuron with a soma located in L1-3 of some neocortex in Mmus. This neuron has a multipolar morphology with spiny dendrites concentrating on L1 of the cortex, and has a burst firing electrophysiological signature with highly dynamic dendritic spines. http://purl.obolibrary.org/obo/CL_4042015 VIP-ChAT interneuron http://purl.obolibrary.org/obo/CL_0008061 GABA-Chol neuron A VIP GABAergic cortical interneuron expressing vasoactive intestinal polypeptide and choline acetyltransferase in the Mmus neocortex. This interneuron releases both γ-aminobutyric acid and acetylcholine. http://purl.obolibrary.org/obo/CL_4042016 nasal serous secreting cell http://purl.obolibrary.org/obo/CL_0000313 serous secreting cell A serous secreting cell that is part of a submucosal gland in the nasal cavity respiratory epithelium. http://purl.obolibrary.org/obo/CL_4047001 cycling stromal cell http://purl.obolibrary.org/obo/CL_0000499 stromal cell A(n) stromal cell that is cycling. http://purl.obolibrary.org/obo/CL_4047002 cycling glial cell http://purl.obolibrary.org/obo/CL_0000125 glial cell A(n) glial cell that is cycling. http://purl.obolibrary.org/obo/CL_4047003 cycling plasma cell http://purl.obolibrary.org/obo/CL_0000786 plasma cell A(n) plasma cell that is cycling. http://purl.obolibrary.org/obo/CL_4047004 cycling type EC enteroendocrine cell http://purl.obolibrary.org/obo/CL_0000577 type EC enteroendocrine cell A(n) type EC enteroendocrine cell that is cycling. http://purl.obolibrary.org/obo/CL_4047005 cycling neuroblast (sensu Vertebrata) http://purl.obolibrary.org/obo/CL_0000031 neuroblast (sensu Vertebrata) A(n) neuroblast (sensu Vertebrata) that is cycling. http://purl.obolibrary.org/obo/UBERON_8600138 stomach lamina propria http://purl.obolibrary.org/obo/UBERON_0004780 gastrointestinal system lamina propria The lamina propria that underlies the epithelial lining of the stomach. http://purl.obolibrary.org/obo/CL_4300353 Purkinje cell (Mmus) http://purl.obolibrary.org/obo/CL_4300028 cerebellar GABAergic neuron (Mmus) A Purkinje cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Pcp2 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Subclass:313 CBX Purkinje Gaba. http://purl.obolibrary.org/obo/CL_0020017 M0 macrophage http://purl.obolibrary.org/obo/CL_0000235 macrophage A macrophage that has not yet undergone polarization into a specific macrophage subtype. These cells are non-activated and have the potential to differentiate into inflammatory (M1) or alternatively activated (M2) macrophage subtypes in response to appropriate stimuli. http://purl.obolibrary.org/obo/CL_4052108 IgD-negative class switched memory B cell http://purl.obolibrary.org/obo/CL_0001053 IgD-negative memory B cell A class switched memory B cell that lacks IgD on the cell surface. http://purl.obolibrary.org/obo/CL_0020016 osteochondral skeletal stem cell http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell A tissue-specific stem cell with long-term self-renewal capacity that is restricted to generating bone, cartilage, and stromal cell lineages. This cell is primarily located in the growth plate (resting zone), periosteum, and subchondral bone regions, and is marked by high clonogenicity and robust multipotent differentiation potential in both osteogenic and chondrogenic lineages. Distinctively, ocSSC lacks adipogenic capacity, distinguishing it from other mesenchymal stem cell populations. http://purl.obolibrary.org/obo/CL_0020018 proliferative fibrochondrocyte http://purl.obolibrary.org/obo/CL_4072104 fibrochondrocyte A fibrochondrocyte located in fibrocartilage that exhibits active proliferation capacity and is in S phase of the cell cycle. It functions as a progenitor cell positioned at the root of developmental trajectories alongside fibrochondrocyte progenitors (FCP), with the capacity to diverge toward one of two developmental fates: (1) fibrochondrocytes and prehypertrophic chondrocytes, or (2) regulatory chondrocytes and prehypertrophic chondrocytes. It is characterised by co-expression of COL1A1, the growth factors FGF7 and CTGF, and the cell-cycle genes STMN1, KIAA0101, and MCM3 in humans. During early progenitor differentiation, FGF7 and COL1A1 expression increases and then declines as the cell commits to terminal fates. http://purl.obolibrary.org/obo/CL_4072104 fibrochondrocyte http://purl.obolibrary.org/obo/CL_0000138 chondrocyte A chondrocyte with hybrid fibroblastic-chondrogenic characteristics found in fibrocartilage, particularly in the avascular inner zone and transitional middle zone of the meniscus. In humans, fibrochondrocytes are marked by predominant expression of type I collagen (COL1A1) and fibril-associated collagens (COL3A1, COL6A1), while retaining type II collagen (COL2A1) expression and exhibiting lower SOX9 than hyaline chondrocytes. This molecular profile underlies the synthesis of abundant type I collagen essential for fibrocartilage matrix and reflects an intermediate phenotype between fibroblast and chondrocyte. http://purl.obolibrary.org/obo/CL_0020019 regulatory chondrocyte http://purl.obolibrary.org/obo/CL_0000138 chondrocyte A chondrocyte located mainly in the superficial zone of articular cartilage. In healthy human cartilage, regulatory chondrocytes are characterized by expression of EIF5A, PGK1, ANXA1, and TUBA1A. During osteoarthritis, a distinct subpopulation expands, marked by high expression of CHI3L1, CHI3L2, CRTAC1, and AEBP1, with enrichment for signaling pathway regulation (including Toll-like receptor, mTOR, and TGF-beta signaling) and antigen-processing gene expression, with a small proportion expressing MHC class II genes, suggesting potential immune cell-like regulatory functions during osteoarthritis progression. http://purl.obolibrary.org/obo/CL_0020020 homeostatic chondrocyte http://purl.obolibrary.org/obo/CL_0000138 chondrocyte A chondrocyte identified in both healthy and osteoarthritic human articular cartilage, and in intervertebral disc tissue. In healthy articular cartilage, a homeostatic chondrocyte is characterised by the expression of TXNIP, IFITM3, GDF15, and TIMP1 (Wang et al., 2021), among other extracellular matrix and regulatory molecules. This cell maintains cartilage integrity by producing key ECM components and supporting baseline tissue homeostasis. In OA cartilage, this cell is enriched for genes related to cellular homeostasis modulation, including regulation of the cell cycle, development, and RNA metabolism (Ji et al., 2018). http://purl.obolibrary.org/obo/CL_0020021 fibrochondrocyte progenitor cell http://purl.obolibrary.org/obo/CL_0008019 mesenchymal cell A mesenchymal progenitor cell located in fibrocartilaginous tissues, along the fibrochondrocytic differentiation pathway that co-expresses both fibrochondrocyte markers (COL1A1, COL3A1) and mesenchymal stem cell markers (MCAM/CD146, MYLK) in humans. This cell serves as a progenitor for mature fibrochondrocytes and other meniscal cell types, with differentiation regulated by TGF-β signaling, focal adhesion, and extracellular matrix-receptor interaction pathways. http://purl.obolibrary.org/obo/CL_0020022 prehypertrophic chondrocyte http://purl.obolibrary.org/obo/CL_0000138 chondrocyte A post-proliferative chondrocyte in the prehypertrophic zone of the cartilage tissue, located between the proliferative and hypertrophic zones. This cell is characterised by increased cell volume and expression of Indian Hedgehog (Ihh), PTH1R, and Runx2/3 in both humans and mice (Hallett et al., 2021). It coordinates the PTHrP-Ihh feedback loop that regulates chondrocyte differentiation and functions as a signalling hub for communication between proliferative chondrocytes, hypertrophic chondrocytes, and periosteal osteoblasts (Hallett et al., 2021). http://purl.obolibrary.org/obo/CL_0020023 effector chondrocyte http://purl.obolibrary.org/obo/CL_0000138 chondrocyte A metabolically highly active chondrocyte that is identified in the cartilaginous tissues, including articular cartilage and intervertebral disc cartilage. In the human articular cartilage, this cell is marked by genes such as CYTL1, FRZB, CLEC3A, and S100B (Ji et al., 2018; Raut et al.,2025). This cell demonstrates strong metabolic activity and is implicated in extracellular matrix regulation and adaptive responses (Ji et al., 2018; Gan et al., 2021; Raut et al.,2025). http://purl.obolibrary.org/obo/CL_0020024 alpha retinal ganglion cell OFF-sustained (Mmus) http://purl.obolibrary.org/obo/CL_0004117 alpha retinal ganglion cell (Mmus) A mouse retinal ganglion cell type defined by a large soma and a wide, monostratified dendritic arbor that stratifies just distal to the outer ChAT band of the inner plexiform layer (Krieger et al., 2017). It corresponds to the G5 physiological type (Baden et al., 2016; Goetz et al., 2022) and the C42 transcriptomic cluster (Tran et al., 2019), and is considered the evolutionary ortholog of the primate OFF midget RGC (Hahn et al., 2023). The cell projects a thick, fast-conducting axon to the dorsal lateral geniculate nucleus and superior colliculus. It shows a sustained increase in firing to light decrements with a slow decay time constant of roughly 250 ms and a large receptive field center with weak surround antagonism (Krieger et al., 2017). Its molecular profile includes expression of Spp1 and Neurofilament (Smi32) together with Brn3a (Pou4f1) and Brn3b (Pou4f2), absence of Brn3c (Pou4f3) and Calbindin (Calb1), and strong enrichment of Fes (Krieger et al., 2017; Tran et al., 2019). http://purl.obolibrary.org/obo/CL_0020025 alpha retinal ganglion cell ON-sustained (Mmus) http://purl.obolibrary.org/obo/CL_4023032 ON retinal ganglion cell A retinal ganglion cell type that has a large soma and a wide, monostratified dendritic arbor that stratifies in the inner sublamina of the inner plexiform layer, with dendrites located just proximal to the inner ChAT band (Krieger et al., 2017). It shows a sustained increase in firing rate to ON stimuli (Krieger et al., 2017). It corresponds to the G24 functional type (Baden et al., 2016; Goetz et al., 2022), the C43 transcriptomic cluster (Tran et al., 2019), and is considered the mouse ortholog of the primate ON midget retinal ganglion cell (Hahn et al., 2023). It is molecularly defined by expression of Spp1, Smi32, Brn3b, Calbindin, and Tbr2 (Krieger et al., 2017; Tran et al., 2019). http://purl.obolibrary.org/obo/CL_0020026 alpha retinal ganglion cell OFF-transient (Mmus) http://purl.obolibrary.org/obo/CL_0004117 alpha retinal ganglion cell (Mmus) An alpha retinal ganglion cell subtype found in the mouse retina that responds selectively and transiently to decreases in light intensity. It is characterized by a large soma, a broad dendritic arbor that stratifies within sublamina a of the inner plexiform layer, and rapid OFF-transient firing kinetics that decay even during sustained stimulation (Krieger et al., 2017). Functionally, it corresponds to G8 in the Baden functional classification (Baden et al., 2016; Goetz et al., 2022) and C45 in the Tran transcriptomic atlas (Tran et al., 2019), and it is considered the evolutionary ortholog of the primate OFF Parasol RGC (Hahn et al., 2023). This cell type acts as a detector of rapidly approaching dark objects and contributes to innate defensive responses by encoding looming stimuli (Münch et al., 2009). It exhibits a distinctive molecular signature by its expression of Brn3c (Krieger et al., 2017). http://purl.obolibrary.org/obo/CL_0020027 alpha retinal ganglion cell ON-transient (Mmus) http://purl.obolibrary.org/obo/CL_4023032 ON retinal ganglion cell An alpha retinal ganglion cell subtype in the mouse retina that responds selectively and transiently to increases in light intensity. It possesses the large soma and expansive dendritic field characteristic of alpha RGCs (Krieger et al., 2017). This cell exhibits a brief, fast-decaying burst of firing at the onset of light increments and contributes to motion detection for luminance increases, forming the ON-branch of the transient magnocellular-like pathway (Krieger et al., 2017; Hahn et al., 2023). Functionally, it corresponds to cluster G19 and aligns transcriptomically with cluster C41 (Krieger et al., 2017; Tran et al., 2019). It is orthologous to the primate ON Parasol RGC (Hahn et al., 2023). Molecularly, it expresses Spp1, Smi32, and Brn3b, but lacks Brn3a, Brn3c, and Calbindin (Krieger et al., 2017). http://purl.obolibrary.org/obo/CL_0020059 serous demilune cell of salivary gland http://purl.obolibrary.org/obo/CL_0000313 serous secreting cell A serous secreting cell that is part of a salivary gland, forming crescent-shaped (demilune) caps at the distal ends of mucous acini in mixed glands. Prominent in human submandibular and sublingual glands, this cell delivers its watery, enzyme-rich secretions including alpha-amylase through intercellular canaliculi that run between adjacent mucous cells to reach the acinar lumen (Amano et al., 2012). In rodents, these cells also express neuronal nitric oxide synthase (nNOS). http://purl.obolibrary.org/obo/CL_0020060 basal duct cell of salivary gland http://purl.obolibrary.org/obo/CL_0000646 basal cell A basal cell that is part of the duct of a salivary gland, characterized by an undifferentiated phenotype, expression of KRT5, and a position surrounding the striated ductal epithelium. This cell is presumed to function as a salivary gland stem/progenitor cell capable of regenerating ductal and potentially acinar cell populations (Yura and Hamada, 2023). In mice, Lgr5-expressing cells within this compartment demonstrate tripotent capacity, able to generate acinar, ductal, and myoepithelial cell lineages. http://purl.obolibrary.org/obo/CL_0020061 periductal fibroblast of salivary gland http://purl.obolibrary.org/obo/CL_0000057 fibroblast A fibroblast that is part of the stroma of a salivary gland, positioned in the periductal connective tissue surrounding the ductal system. This cell maintains the extracellular matrix framework around salivary gland ducts and participates in immunomodulatory signaling. In the context of Sjögren's syndrome, periductal fibroblasts respond to IL-13 stimulation by upregulating VCAM-1, PDPN, and ICAM-1, contributing to the formation of tertiary lymphoid structures (Nayar et al., 2019). http://purl.obolibrary.org/obo/CL_0020062 junctional epithelial cell http://purl.obolibrary.org/obo/CL_0002251 epithelial cell of alimentary canal An epithelial cell that is part of the junctional epithelium of the gingiva, forming a collar-like band around the cervix of the tooth. This cell attaches to the tooth surface via hemidesmosomes and an internal basal lamina rich in laminin-332 and ODAM (Gavriiloglou et al., 2024). The junctional epithelium is a stratified squamous non-keratinized epithelium ranging from 15-30 cell layers coronally to 1-3 cell layers apically. This cell expresses cytokeratin 19 (CK19) as a specific marker, along with ODAM and FDC-SP, and participates in innate immune defense by producing IL-8, IL-1alpha, and MMP-7, facilitating the transmigration of polymorphonuclear leukocytes through the epithelium (Gavriiloglou et al., 2024). This cell has a high turnover rate, with complete renewal occurring every 4-6 days (Lin et al., 2025), and develops from the reduced enamel epithelium during tooth eruption, although it can regenerate de novo without this precursor. http://purl.obolibrary.org/obo/CL_0020063 tuft cell of parotid gland http://purl.obolibrary.org/obo/CL_0002204 tuft cell A tuft cell that is part of the epithelium of the parotid gland, localized to the striated ducts and never observed in acini. This cell is characterized by expression of POU2F3 and is expected to possess chemosensory function consistent with tuft cells in other tissues. Immunohistochemical analysis of normal human parotid gland tissue detected POU2F3-positive cells as a very rare population within the ductal compartment, positioned on the luminal side (Hoki et al., 2024). http://purl.obolibrary.org/obo/CL_0020064 tuft cell of sublingual gland http://purl.obolibrary.org/obo/CL_0002251 epithelial cell of alimentary canal A tuft cell that is part of the epithelium of the sublingual gland, localized to the ductal compartment. This cell is characterized by expression of POU2F3, consistent with tuft cell identity. Immunohistochemical analysis detected POU2F3-positive cells in normal human sublingual gland tissue (Hoki et al., 2024). http://purl.obolibrary.org/obo/CL_0020065 ionocyte of salivary gland http://purl.obolibrary.org/obo/CL_0005006 ionocyte An ionocyte that is part of a salivary gland, localized to the ductal compartment on the luminal side. This specialized epithelial cell is characterized by expression of FOXI1 and is involved in regulating and maintaining osmotic pressure within the glandular environment (Dong et al., 2024). In normal human salivary glands, FOXI1-positive cells constitute less than 5% of ductal epithelial cells and are found exclusively in ducts, never in acini, across all major gland types including parotid, submandibular, sublingual, and minor salivary glands (Hoki et al., 2024). Like ionocytes in other tissues, this cell is expected to express high levels of CFTR and possess abundant mitochondria and ion transporters. http://purl.obolibrary.org/obo/CL_0020066 myoepithelial cell of salivary gland http://purl.obolibrary.org/obo/CL_0000185 myoepithelial cell A myoepithelial cell that is part of a salivary gland, positioned between the basal lamina and the secretory or ductal epithelial cells surrounding acini and intercalated ducts. This cell adopts a stellate morphology with four to eight cellular processes around acini and an elongated form parallel to the ductal axis around intercalated ducts (Amano et al., 2012). It expresses alpha-smooth muscle actin (ACTA2/alpha-SMA) as a primary marker, along with p63 and aquaporin 1 (AQP1), and contracts rhythmically in response to neural stimulation to facilitate saliva expulsion from secretory acini into the ductal system (Amano et al., 2012). This cell also produces FGF7, which activates FGFR2b-dependent transcriptional programs essential for seromucous acinar cell differentiation (Aure et al., 2023). In mice, myoepithelial cells express SOX2 and possess regenerative capacity, contributing to acinar cell restoration during tissue repair after severe injury. http://purl.obolibrary.org/obo/GO_0000001 mitochondrion inheritance http://purl.obolibrary.org/obo/GO_0048311 mitochondrion distribution The distribution of mitochondria, including the mitochondrial genome, into daughter cells after mitosis or meiosis, mediated by interactions between mitochondria and the cytoskeleton. http://purl.obolibrary.org/obo/GO_0000011 vacuole inheritance http://purl.obolibrary.org/obo/GO_0048308 organelle inheritance The distribution of vacuoles into daughter cells after mitosis or meiosis, mediated by interactions between vacuoles and the cytoskeleton. http://purl.obolibrary.org/obo/GO_0000018 regulation of DNA recombination http://purl.obolibrary.org/obo/GO_0051052 regulation of DNA metabolic process Any process that modulates the frequency, rate or extent of DNA recombination, a DNA metabolic process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. http://purl.obolibrary.org/obo/GO_0000041 transition metal ion transport http://purl.obolibrary.org/obo/GO_0030001 metal ion transport The directed movement of transition metal ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver. http://purl.obolibrary.org/obo/GO_0000048 peptidyltransferase activity http://purl.obolibrary.org/obo/GO_0140101 catalytic activity, acting on a tRNA Catalysis of the reaction: peptidyl-tRNA(1) + aminoacyl-tRNA(2) = tRNA(1) + peptidylaminoacyl-tRNA(2). This reaction is catalyzed by a ribozyme. http://purl.obolibrary.org/obo/GO_0000049 tRNA binding http://purl.obolibrary.org/obo/GO_0003723 RNA binding Binding to a transfer RNA. http://purl.obolibrary.org/obo/GO_0000070 mitotic sister chromatid segregation http://purl.obolibrary.org/obo/GO_1903047 mitotic cell cycle process The cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the mitotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner. One homolog of each morphologic type goes into each of the resulting chromosome sets. http://purl.obolibrary.org/obo/GO_0000105 L-histidine biosynthetic process http://purl.obolibrary.org/obo/GO_0170038 proteinogenic amino acid biosynthetic process The chemical reactions and pathways resulting in the formation of L-histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid. http://purl.obolibrary.org/obo/GO_0000139 Golgi membrane http://purl.obolibrary.org/obo/GO_0098588 bounding membrane of organelle The lipid bilayer surrounding any of the compartments of the Golgi apparatus. http://purl.obolibrary.org/obo/GO_0000166 nucleotide binding http://purl.obolibrary.org/obo/GO_1901363 heterocyclic compound binding Binding to a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose. http://purl.obolibrary.org/obo/GO_0000226 microtubule cytoskeleton organization http://purl.obolibrary.org/obo/GO_0007017 microtubule-based process A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins. http://purl.obolibrary.org/obo/GO_0000228 nuclear chromosome http://purl.obolibrary.org/obo/GO_0005694 chromosome A chromosome that encodes the nuclear genome and is found in the nucleus of a eukaryotic cell during the cell cycle phases when the nucleus is intact. http://purl.obolibrary.org/obo/GO_0000262 mitochondrial chromosome http://purl.obolibrary.org/obo/GO_0005694 chromosome A chromosome found in the mitochondrion of a eukaryotic cell. http://purl.obolibrary.org/obo/GO_0000266 mitochondrial fission http://purl.obolibrary.org/obo/GO_0048285 organelle fission The division of a mitochondrion within a cell to form two or more separate mitochondrial compartments. http://purl.obolibrary.org/obo/GO_0000271 polysaccharide biosynthetic process http://purl.obolibrary.org/obo/GO_0016051 carbohydrate biosynthetic process The chemical reactions and pathways resulting in the formation of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically. http://purl.obolibrary.org/obo/GO_0000272 polysaccharide catabolic process http://purl.obolibrary.org/obo/GO_0016052 carbohydrate catabolic process The chemical reactions and pathways resulting in the breakdown of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically. http://purl.obolibrary.org/obo/GO_0000278 mitotic cell cycle http://purl.obolibrary.org/obo/GO_0007049 cell cycle Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent. http://purl.obolibrary.org/obo/GO_0000279 M phase http://purl.obolibrary.org/obo/GO_0022403 cell cycle phase A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase. http://purl.obolibrary.org/obo/GO_0000280 nuclear division http://purl.obolibrary.org/obo/GO_0048285 organelle fission The division of a cell nucleus into two nuclei, with DNA and other nuclear contents distributed between the daughter nuclei. http://purl.obolibrary.org/obo/GO_0000295 adenine nucleotide transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0015216 purine nucleotide transmembrane transporter activity Enables the transfer of adenine nucleotides (AMP, ADP, and ATP) from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0000302 response to reactive oxygen species http://purl.obolibrary.org/obo/GO_1901700 response to oxygen-containing compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals. http://purl.obolibrary.org/obo/GO_0000303 response to superoxide http://purl.obolibrary.org/obo/GO_0000305 response to oxygen radical Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a superoxide stimulus. Superoxide is the anion, oxygen-, formed by addition of one electron to dioxygen (O2) or any compound containing the superoxide anion. http://purl.obolibrary.org/obo/GO_0000305 response to oxygen radical http://purl.obolibrary.org/obo/GO_0000302 response to reactive oxygen species Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen radical stimulus. An oxygen radical is any oxygen species that carries a free electron; examples include hydroxyl radicals and the superoxide anion. http://purl.obolibrary.org/obo/GO_0000313 organellar ribosome http://purl.obolibrary.org/obo/GO_0005840 ribosome A ribosome contained within a subcellular membrane-bounded organelle. http://purl.obolibrary.org/obo/GO_0000323 lytic vacuole http://purl.obolibrary.org/obo/GO_0005773 vacuole A vacuole that is maintained at an acidic pH and which contains degradative enzymes, including a wide variety of acid hydrolases. http://purl.obolibrary.org/obo/GO_0000578 embryonic axis specification http://purl.obolibrary.org/obo/GO_0009880 embryonic pattern specification The establishment, maintenance and elaboration of a pattern along a line or a point in an embryo. http://purl.obolibrary.org/obo/GO_0000740 nuclear membrane fusion http://purl.obolibrary.org/obo/GO_0071763 nuclear membrane organization The joining of 2 or more lipid bilayer membranes that surround the nucleus. http://purl.obolibrary.org/obo/GO_0000741 karyogamy http://purl.obolibrary.org/obo/GO_0048284 organelle fusion The creation of a single nucleus from multiple nuclei as a result of fusing the lipid bilayers that surround each nuclei. http://purl.obolibrary.org/obo/GO_0000768 syncytium formation by plasma membrane fusion http://purl.obolibrary.org/obo/GO_0006949 syncytium formation The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells. http://purl.obolibrary.org/obo/GO_0000785 chromatin http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome. http://purl.obolibrary.org/obo/GO_0000791 euchromatin http://purl.obolibrary.org/obo/GO_0000785 chromatin A dispersed and relatively uncompacted form of chromatin that is in a transcription-competent conformation. http://purl.obolibrary.org/obo/GO_0000792 heterochromatin http://purl.obolibrary.org/obo/GO_0000785 chromatin A compact and highly condensed form of chromatin that is refractory to transcription. http://purl.obolibrary.org/obo/GO_0000803 sex chromosome http://purl.obolibrary.org/obo/GO_0005694 chromosome A chromosome involved in sex determination. http://purl.obolibrary.org/obo/GO_0000819 sister chromatid segregation http://purl.obolibrary.org/obo/GO_0098813 nuclear chromosome segregation The cell cycle process in which sister chromatids are organized and then physically separated and apportioned to two or more sets. http://purl.obolibrary.org/obo/GO_0000902 cell morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The developmental process in which the size or shape of a cell is generated and organized. http://purl.obolibrary.org/obo/GO_0000957 mitochondrial RNA catabolic process http://purl.obolibrary.org/obo/GO_0006401 RNA catabolic process The chemical reactions and pathways resulting in the breakdown of RNA transcribed from the mitochondrial genome and occurring in the mitochondrion. http://purl.obolibrary.org/obo/GO_0000959 mitochondrial RNA metabolic process http://purl.obolibrary.org/obo/GO_0016070 RNA metabolic process The chemical reactions and pathways involving RNA transcribed from the mitochondrial genome and occurring in the mitochondrion. http://purl.obolibrary.org/obo/GO_0000960 regulation of mitochondrial RNA catabolic process http://purl.obolibrary.org/obo/GO_0009894 regulation of catabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving catabolism in the mitochondrion of RNA transcribed from the mitochondrial genome. http://purl.obolibrary.org/obo/GO_0000961 negative regulation of mitochondrial RNA catabolic process http://purl.obolibrary.org/obo/GO_1902369 negative regulation of RNA catabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving catabolism in the mitochondrion of RNA transcribed from the mitochondrial genome. http://purl.obolibrary.org/obo/GO_0000962 positive regulation of mitochondrial RNA catabolic process http://purl.obolibrary.org/obo/GO_0009896 positive regulation of catabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving catabolism in the mitochondrion of RNA transcribed from the mitochondrial genome. http://purl.obolibrary.org/obo/GO_0001101 response to acid chemical http://purl.obolibrary.org/obo/GO_0042221 response to chemical Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by the chemical structure of the anion portion of a dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form. http://purl.obolibrary.org/obo/GO_0001501 skeletal system development http://purl.obolibrary.org/obo/GO_0048731 system development The process whose specific outcome is the progression of the skeleton over time, from its formation to the mature structure. The skeleton is the bony framework of the body in vertebrates (endoskeleton) or the hard outer envelope of insects (exoskeleton or dermoskeleton). http://purl.obolibrary.org/obo/GO_0001503 ossification http://purl.obolibrary.org/obo/GO_0032501 multicellular organismal process The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance. http://purl.obolibrary.org/obo/GO_0001504 neurotransmitter uptake http://purl.obolibrary.org/obo/GO_0098657 import into cell The directed movement of neurotransmitters into neurons or glial cells. This process leads to inactivation and recycling of neurotransmitters. http://purl.obolibrary.org/obo/GO_0001507 acetylcholine catabolic process in synaptic cleft http://purl.obolibrary.org/obo/GO_0006581 acetylcholine catabolic process The chemical reactions and pathways resulting in the breakdown of acetylcholine that occurs in the synaptic cleft during synaptic transmission. http://purl.obolibrary.org/obo/GO_0001508 action potential http://purl.obolibrary.org/obo/GO_0042391 regulation of membrane potential A process in which membrane potential cycles through a depolarizing spike, triggered in response to depolarization above some threshold, followed by repolarization. This cycle is driven by the flow of ions through various voltage gated channels with different thresholds and ion specificities. http://purl.obolibrary.org/obo/GO_0001518 voltage-gated sodium channel complex http://purl.obolibrary.org/obo/GO_0098797 plasma membrane protein complex A sodium channel in a cell membrane whose opening is governed by the membrane potential. http://purl.obolibrary.org/obo/GO_0001525 angiogenesis http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels. http://purl.obolibrary.org/obo/GO_0001534 radial spoke http://purl.obolibrary.org/obo/GO_0032991 protein-containing complex Protein complex that links the outer microtubule doublet of a 9+2 type ciliary or flagellar axoneme with the sheath that surrounds the central pair of microtubules. Composed of a stalk that attaches to each doublet microtubule and a globular structure (spoke head) that projects toward the central pair of microtubules. http://purl.obolibrary.org/obo/GO_0001539 cilium or flagellum-dependent cell motility http://purl.obolibrary.org/obo/GO_0048870 cell motility Cell motility due to movement of eukaryotic cilia or bacterial-type flagella or archaeal-type flagella. http://purl.obolibrary.org/obo/GO_0001541 ovarian follicle development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the ovarian follicle over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0001545 primary ovarian follicle growth http://purl.obolibrary.org/obo/GO_0048589 developmental growth Increase in size of primary follicles including oocyte growth and granulosa and/or theca cell proliferation until more than one layer of granulosa cells is present (preantral follicle). http://purl.obolibrary.org/obo/GO_0001546 preantral ovarian follicle growth http://purl.obolibrary.org/obo/GO_0048589 developmental growth Increase in size of follicles surrounded by two or more layers of granulosa cells up to the onset of antrum formation. http://purl.obolibrary.org/obo/GO_0001547 antral ovarian follicle growth http://purl.obolibrary.org/obo/GO_0048589 developmental growth Increase in size of antral follicles due to cell proliferation and/or growth of the antral cavity. http://purl.obolibrary.org/obo/GO_0001549 cumulus cell differentiation http://purl.obolibrary.org/obo/GO_0060014 granulosa cell differentiation The process in which a subpopulation of granulosa cells surrounding the oocyte acquires the specialized features of an ovarian cumulus cell. http://purl.obolibrary.org/obo/GO_0001552 ovarian follicle atresia http://purl.obolibrary.org/obo/GO_0003006 developmental process involved in reproduction A periodic process in which immature ovarian follicles degenerate and are subsequently re-absorbed. http://purl.obolibrary.org/obo/GO_0001553 luteinization http://purl.obolibrary.org/obo/GO_0022602 ovulation cycle process The set of processes resulting in differentiation of theca and granulosa cells into luteal cells and in the formation of a corpus luteum after ovulation. http://purl.obolibrary.org/obo/GO_0001555 oocyte growth http://purl.obolibrary.org/obo/GO_0048588 developmental cell growth The developmental growth process in which an oocyte irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present. http://purl.obolibrary.org/obo/GO_0001556 oocyte maturation http://purl.obolibrary.org/obo/GO_0048469 cell maturation A developmental process, independent of morphogenetic (shape) change, that is required for an oocyte to attain its fully functional state. Oocyte maturation commences after reinitiation of meiosis commonly starting with germinal vesicle breakdown, and continues up to the second meiotic arrest prior to fertilization. http://purl.obolibrary.org/obo/GO_0001558 regulation of cell growth http://purl.obolibrary.org/obo/GO_0051128 regulation of cellular component organization Any process that modulates the frequency, rate, extent or direction of cell growth. http://purl.obolibrary.org/obo/GO_0001560 regulation of cell growth by extracellular stimulus http://purl.obolibrary.org/obo/GO_0001558 regulation of cell growth Any process in which external signals modulate the frequency, rate or extent of cell growth, the irreversible increase in size of a cell over time. http://purl.obolibrary.org/obo/GO_0001568 blood vessel development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of a blood vessel over time, from its formation to the mature structure. The blood vessel is the vasculature carrying blood. http://purl.obolibrary.org/obo/GO_0001569 branching involved in blood vessel morphogenesis http://purl.obolibrary.org/obo/GO_0048754 branching morphogenesis of an epithelial tube The process of coordinated growth and sprouting of blood vessels giving rise to the organized vascular system. http://purl.obolibrary.org/obo/GO_0001570 vasculogenesis http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The differentiation of endothelial cells from progenitor cells during blood vessel development, and the de novo formation of blood vessels and tubes. http://purl.obolibrary.org/obo/GO_0001578 microtubule bundle formation http://purl.obolibrary.org/obo/GO_0000226 microtubule cytoskeleton organization A process that results in a parallel arrangement of microtubules. http://purl.obolibrary.org/obo/GO_0001614 purinergic nucleotide receptor activity http://purl.obolibrary.org/obo/GO_0016502 nucleotide receptor activity Combining with a purine nucleotide and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. http://purl.obolibrary.org/obo/GO_0001621 G protein-coupled ADP receptor activity http://purl.obolibrary.org/obo/GO_0045028 G protein-coupled purinergic nucleotide receptor activity Combining with ADP and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. http://purl.obolibrary.org/obo/GO_0001649 osteoblast differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process whereby a relatively unspecialized cell acquires the specialized features of an osteoblast, a mesodermal or neural crest cell that gives rise to bone. http://purl.obolibrary.org/obo/GO_0001653 peptide receptor activity http://purl.obolibrary.org/obo/GO_0038023 signaling receptor activity Combining with an extracellular or intracellular peptide to initiate a change in cell activity. http://purl.obolibrary.org/obo/GO_0001654 eye development http://purl.obolibrary.org/obo/GO_0007423 sensory organ development The process whose specific outcome is the progression of the eye over time, from its formation to the mature structure. The eye is the organ of sight. http://purl.obolibrary.org/obo/GO_0001655 urogenital system development http://purl.obolibrary.org/obo/GO_0048731 system development The process whose specific outcome is the progression of the urogenital system over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0001656 metanephros development http://purl.obolibrary.org/obo/GO_0001822 kidney development The process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. In mammals, the metanephros is the excretory organ of the fetus, which develops into the mature kidney and is formed from the rear portion of the nephrogenic cord. The metanephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine. http://purl.obolibrary.org/obo/GO_0001657 ureteric bud development http://purl.obolibrary.org/obo/GO_0072164 mesonephric tubule development The process whose specific outcome is the progression of the ureteric bud over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0001658 branching involved in ureteric bud morphogenesis http://purl.obolibrary.org/obo/GO_0048754 branching morphogenesis of an epithelial tube The process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules. http://purl.obolibrary.org/obo/GO_0001659 temperature homeostasis http://purl.obolibrary.org/obo/GO_0048871 multicellular organismal-level homeostasis A homeostatic process in which an organism modulates its internal body temperature. http://purl.obolibrary.org/obo/GO_0001664 G protein-coupled receptor binding http://purl.obolibrary.org/obo/GO_0005102 signaling receptor binding Binding to a G protein-coupled receptor. http://purl.obolibrary.org/obo/GO_0001666 response to hypoxia http://purl.obolibrary.org/obo/GO_0036293 response to decreased oxygen levels Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level. http://purl.obolibrary.org/obo/GO_0001667 ameboidal-type cell migration http://purl.obolibrary.org/obo/GO_0016477 cell migration Cell migration that is accomplished by extension and retraction of a pseudopodium. http://purl.obolibrary.org/obo/GO_0001669 acrosomal vesicle http://purl.obolibrary.org/obo/GO_0030141 secretory granule A structure in the head of a spermatozoon that contains acid hydrolases, and is concerned with the breakdown of the outer membrane of the ovum during fertilization. It lies just beneath the plasma membrane and is derived from the lysosome. http://purl.obolibrary.org/obo/GO_0001673 male germ cell nucleus http://purl.obolibrary.org/obo/GO_0043073 germ cell nucleus The nucleus of a male germ cell, a reproductive cell in males. http://purl.obolibrary.org/obo/GO_0001674 female germ cell nucleus http://purl.obolibrary.org/obo/GO_0043073 germ cell nucleus The nucleus of the female germ cell, a reproductive cell in females. http://purl.obolibrary.org/obo/GO_0001675 acrosome assembly http://purl.obolibrary.org/obo/GO_0070925 organelle assembly The formation of the acrosome from the spermatid Golgi. http://purl.obolibrary.org/obo/GO_0001677 formation of translation initiation ternary complex http://purl.obolibrary.org/obo/GO_0022618 protein-RNA complex assembly Formation of a complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2 (either eIF2 in eukaryotes, or IF2 in prokaryotes). In prokaryotes, fMet-tRNA (initiator) is used rather than Met-tRNA (initiator). http://purl.obolibrary.org/obo/GO_0001678 intracellular glucose homeostasis http://purl.obolibrary.org/obo/GO_0055082 intracellular chemical homeostasis A homeostatic process involved in the maintenance of a steady state level of glucose within a cell. http://purl.obolibrary.org/obo/GO_0001692 histamine metabolic process http://purl.obolibrary.org/obo/GO_0052803 imidazole-containing compound metabolic process The chemical reactions and pathways involving histamine, a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans. http://purl.obolibrary.org/obo/GO_0001694 histamine biosynthetic process http://purl.obolibrary.org/obo/GO_0042401 biogenic amine biosynthetic process The chemical reactions and pathways resulting in the formation of histamine, a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans. http://purl.obolibrary.org/obo/GO_0001695 histamine catabolic process http://purl.obolibrary.org/obo/GO_0052805 imidazole-containing compound catabolic process The chemical reactions and pathways resulting in the breakdown of histamine, a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans. http://purl.obolibrary.org/obo/GO_0001696 gastric acid secretion http://purl.obolibrary.org/obo/GO_0046717 acid secretion The regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion. http://purl.obolibrary.org/obo/GO_0001700 embryonic development via the syncytial blastoderm http://purl.obolibrary.org/obo/GO_0009792 embryo development ending in birth or egg hatching The process whose specific outcome is the progression of the embryo over time, from zygote formation through syncytial blastoderm to the hatching of the first instar larva. An example of this process is found in Drosophila melanogaster. http://purl.obolibrary.org/obo/GO_0001701 in utero embryonic development http://purl.obolibrary.org/obo/GO_0043009 chordate embryonic development The process whose specific outcome is the progression of the embryo in the uterus over time, from formation of the zygote in the oviduct, to birth. An example of this process is found in Mus musculus. http://purl.obolibrary.org/obo/GO_0001702 gastrulation with mouth forming second http://purl.obolibrary.org/obo/GO_0007369 gastrulation A gastrulation process in which the initial invagination becomes the anus and the mouth forms second. http://purl.obolibrary.org/obo/GO_0001703 gastrulation with mouth forming first http://purl.obolibrary.org/obo/GO_0007369 gastrulation A gastrulation process in which the initial invagination becomes the mouth and the anus forms second. http://purl.obolibrary.org/obo/GO_0001704 formation of primary germ layer http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The formation of the ectoderm, mesoderm and endoderm during gastrulation. http://purl.obolibrary.org/obo/GO_0001705 ectoderm formation http://purl.obolibrary.org/obo/GO_0001704 formation of primary germ layer The formation of ectoderm during gastrulation. http://purl.obolibrary.org/obo/GO_0001706 endoderm formation http://purl.obolibrary.org/obo/GO_0001704 formation of primary germ layer The formation of the endoderm during gastrulation. http://purl.obolibrary.org/obo/GO_0001707 mesoderm formation http://purl.obolibrary.org/obo/GO_0001704 formation of primary germ layer The process that gives rise to the mesoderm. This process pertains to the initial formation of the structure from unspecified parts. http://purl.obolibrary.org/obo/GO_0001739 sex chromatin http://purl.obolibrary.org/obo/GO_0000792 heterochromatin Chromatin that is part of a sex chromosome. http://purl.obolibrary.org/obo/GO_0001742 oenocyte differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of an oenocyte. Oenocytes are large secretory cells found in clusters underlying the epidermis of larval abdominal segments. http://purl.obolibrary.org/obo/GO_0001743 lens placode formation http://purl.obolibrary.org/obo/GO_0060788 ectodermal placode formation The initial developmental process that will lead to the formation of an eye. http://purl.obolibrary.org/obo/GO_0001745 compound eye morphogenesis http://purl.obolibrary.org/obo/GO_0048592 eye morphogenesis The morphogenetic process in which the anatomical structures of the compound eye are generated and organized. The adult compound eye is a precise assembly of 700-800 ommatidia. Each ommatidium is composed of 20 cells, identified by cell type and position. An example of compound eye morphogenesis is found in Drosophila melanogaster. http://purl.obolibrary.org/obo/GO_0001751 compound eye photoreceptor cell differentiation http://purl.obolibrary.org/obo/GO_0001754 eye photoreceptor cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of an eye photoreceptor cell. http://purl.obolibrary.org/obo/GO_0001754 eye photoreceptor cell differentiation http://purl.obolibrary.org/obo/GO_0046530 photoreceptor cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a photoreceptor cell, as found in the eye, the primary visual organ of most organisms. http://purl.obolibrary.org/obo/GO_0001755 neural crest cell migration http://purl.obolibrary.org/obo/GO_0090497 mesenchymal cell migration The characteristic movement of cells from the dorsal ridge of the neural tube to a variety of locations in a vertebrate embryo. http://purl.obolibrary.org/obo/GO_0001756 somitogenesis http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The formation of mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo. http://purl.obolibrary.org/obo/GO_0001763 morphogenesis of a branching structure http://purl.obolibrary.org/obo/GO_0032501 multicellular organismal process The process in which the anatomical structures of branches are generated and organized. A branch is a division or offshoot from a main stem. Examples in animals would include blood vessels, nerves, lymphatics and other endothelial or epithelial tubes. http://purl.obolibrary.org/obo/GO_0001764 neuron migration http://purl.obolibrary.org/obo/GO_0016477 cell migration The characteristic movement of an immature neuron from germinal zones to specific positions where they will reside as they mature. http://purl.obolibrary.org/obo/GO_0001767 establishment of lymphocyte polarity http://purl.obolibrary.org/obo/GO_0030010 establishment of cell polarity The directed orientation of lymphocyte signaling molecules and associated membrane rafts towards a chemokine gradient or a contact point with an appropriate activating cell. http://purl.obolibrary.org/obo/GO_0001768 establishment of T cell polarity http://purl.obolibrary.org/obo/GO_0001767 establishment of lymphocyte polarity The directed orientation of T cell signaling molecules and associated membrane rafts towards a chemokine gradient or a contact point with antigen presenting cell. http://purl.obolibrary.org/obo/GO_0001769 establishment of B cell polarity http://purl.obolibrary.org/obo/GO_0001767 establishment of lymphocyte polarity The directed orientation of B cell signaling molecules and associated membrane rafts towards a chemokine gradient of a contact point with an antigen displaying cell. http://purl.obolibrary.org/obo/GO_0001770 establishment of natural killer cell polarity http://purl.obolibrary.org/obo/GO_0001767 establishment of lymphocyte polarity The directed orientation of natural killer cell signaling molecules and associated membrane rafts towards a chemokine gradient or a contact point with a cell displaying natural killer cell activating ligands. http://purl.obolibrary.org/obo/GO_0001773 myeloid dendritic cell activation http://purl.obolibrary.org/obo/GO_0002274 myeloid leukocyte activation The change in morphology and behavior of a dendritic cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. http://purl.obolibrary.org/obo/GO_0001774 microglial cell activation http://purl.obolibrary.org/obo/GO_0061900 glial cell activation The change in morphology and behavior of a microglial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. http://purl.obolibrary.org/obo/GO_0001775 cell activation http://purl.obolibrary.org/obo/GO_0032501 multicellular organismal process A multicellular organismal process by which exposure to an activating factor such as a cellular or soluble ligand results in a change in the morphology or behavior of a cell. http://purl.obolibrary.org/obo/GO_0001776 leukocyte homeostasis http://purl.obolibrary.org/obo/GO_0048872 homeostasis of number of cells The process of regulating the proliferation and elimination of cells of the immune system such that the total number of cells of a particular cell type within a whole or part of an organism is stable over time in the absence of an outside stimulus. http://purl.obolibrary.org/obo/GO_0001777 T cell homeostatic proliferation http://purl.obolibrary.org/obo/GO_0042098 T cell proliferation The non-specific expansion of T cell populations within a whole or part of an organism to reach to a total number of T cells which will then remain stable over time in the absence of an external stimulus. http://purl.obolibrary.org/obo/GO_0001779 natural killer cell differentiation http://purl.obolibrary.org/obo/GO_0030101 natural killer cell activation The process in which a relatively unspecialized cell acquires the specialized features of a natural killer cell. http://purl.obolibrary.org/obo/GO_0001780 neutrophil homeostasis http://purl.obolibrary.org/obo/GO_0002262 myeloid cell homeostasis The process of regulating the proliferation and elimination of neutrophils such that the total number of neutrophils within a whole or part of an organism is stable over time in the absence of an outside stimulus. http://purl.obolibrary.org/obo/GO_0001781 neutrophil apoptotic process http://purl.obolibrary.org/obo/GO_0071887 leukocyte apoptotic process Any apoptotic process in a neutrophil, any of the immature or mature forms of a granular leukocyte that in its mature form has a nucleus with three to five lobes connected by slender threads of chromatin, and cytoplasm containing fine inconspicuous granules and stainable by neutral dyes. http://purl.obolibrary.org/obo/GO_0001782 B cell homeostasis http://purl.obolibrary.org/obo/GO_0002260 lymphocyte homeostasis The process of regulating the proliferation and elimination of B cells such that the total number of B cells within a whole or part of an organism is stable over time in the absence of an outside stimulus. http://purl.obolibrary.org/obo/GO_0001783 B cell apoptotic process http://purl.obolibrary.org/obo/GO_0070227 lymphocyte apoptotic process Any apoptotic process in a B cell, a lymphocyte of B lineage with the phenotype CD19-positive and capable of B cell mediated immunity. http://purl.obolibrary.org/obo/GO_0001787 natural killer cell proliferation http://purl.obolibrary.org/obo/GO_0046651 lymphocyte proliferation The expansion of a natural killer cell population by cell division. http://purl.obolibrary.org/obo/GO_0001816 cytokine production http://purl.obolibrary.org/obo/GO_0032501 multicellular organismal process The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. http://purl.obolibrary.org/obo/GO_0001817 regulation of cytokine production http://purl.obolibrary.org/obo/GO_0051239 regulation of multicellular organismal process Any process that modulates the frequency, rate, or extent of production of a cytokine. http://purl.obolibrary.org/obo/GO_0001818 negative regulation of cytokine production http://purl.obolibrary.org/obo/GO_0051241 negative regulation of multicellular organismal process Any process that stops, prevents, or reduces the rate of production of a cytokine. http://purl.obolibrary.org/obo/GO_0001819 positive regulation of cytokine production http://purl.obolibrary.org/obo/GO_0010628 positive regulation of gene expression Any process that activates or increases the frequency, rate or extent of production of a cytokine. http://purl.obolibrary.org/obo/GO_0001820 serotonin secretion http://purl.obolibrary.org/obo/GO_0023061 signal release The regulated release of serotonin by a cell. Serotonin (5-hydroxytryptamine, or 5-HT) is a monoamine synthesized in serotonergic neurons in the central nervous system, enterochromaffin cells in the gastrointestinal tract and some immune system cells. http://purl.obolibrary.org/obo/GO_0001821 histamine secretion http://purl.obolibrary.org/obo/GO_0051608 histamine transport The regulated release of histamine by a cell or tissue. It is formed by decarboxylation of histidine and it acts through receptors in smooth muscle and in secretory systems. http://purl.obolibrary.org/obo/GO_0001822 kidney development http://purl.obolibrary.org/obo/GO_0048513 animal organ development The process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and/or excretes the end products of body metabolism in the form of urine. http://purl.obolibrary.org/obo/GO_0001823 mesonephros development http://purl.obolibrary.org/obo/GO_0001822 kidney development The process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. In mammals, the mesonephros is the second of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the mesonephros will form the mature kidney. http://purl.obolibrary.org/obo/GO_0001824 blastocyst development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the blastocyst over time, from its formation to the mature structure. The mammalian blastocyst is a hollow ball of cells containing two cell types, the inner cell mass and the trophectoderm. The blastula follows the morula and precedes the gastrula in the developmental sequence. http://purl.obolibrary.org/obo/GO_0001825 blastocyst formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The initial formation of a blastocyst from a solid ball of cells known as a morula. http://purl.obolibrary.org/obo/GO_0001826 inner cell mass cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires specialized features of an inner cell mass cell. http://purl.obolibrary.org/obo/GO_0001829 trophectodermal cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a trophectoderm cell. http://purl.obolibrary.org/obo/GO_0001831 trophectodermal cellular morphogenesis http://purl.obolibrary.org/obo/GO_0048598 embryonic morphogenesis The morphogenesis of trophectoderm cells. http://purl.obolibrary.org/obo/GO_0001832 blastocyst growth http://purl.obolibrary.org/obo/GO_0048589 developmental growth An increase in size of a blastocyst due to expansion of the blastocoelic cavity cell shape changes and cell proliferation. http://purl.obolibrary.org/obo/GO_0001833 inner cell mass cell proliferation http://purl.obolibrary.org/obo/GO_0008283 cell population proliferation The proliferation of cells in the inner cell mass. http://purl.obolibrary.org/obo/GO_0001834 trophectodermal cell proliferation http://purl.obolibrary.org/obo/GO_0008283 cell population proliferation The proliferation of cells in the trophectoderm. http://purl.obolibrary.org/obo/GO_0001837 epithelial to mesenchymal transition http://purl.obolibrary.org/obo/GO_0048762 mesenchymal cell differentiation A transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. http://purl.obolibrary.org/obo/GO_0001838 embryonic epithelial tube formation http://purl.obolibrary.org/obo/GO_0072175 epithelial tube formation The morphogenesis of an embryonic epithelium into a tube-shaped structure. http://purl.obolibrary.org/obo/GO_0001839 neural plate morphogenesis http://purl.obolibrary.org/obo/GO_0016331 morphogenesis of embryonic epithelium The process in which the anatomical structures of the neural plate are generated and organized. The neural plate is a specialized region of columnar epithelial cells in the dorsal ectoderm that will give rise to nervous system tissue. http://purl.obolibrary.org/obo/GO_0001840 neural plate development http://purl.obolibrary.org/obo/GO_0060429 epithelium development The process whose specific outcome is the progression of the neural plate over time, from its formation to the mature structure. The neural plate is a flat, thickened layer of ectodermal cells. The underlying dorsal mesoderm signals the ectodermal cells above it to elongate into columnar neural plate cells. The neural plate subsequently develops into the neural tube, which gives rise to the central nervous system. http://purl.obolibrary.org/obo/GO_0001841 neural tube formation http://purl.obolibrary.org/obo/GO_0001838 embryonic epithelial tube formation The formation of a tube from the flat layer of ectodermal cells known as the neural plate. This will give rise to the central nervous system. http://purl.obolibrary.org/obo/GO_0001842 neural fold formation http://purl.obolibrary.org/obo/GO_0060571 morphogenesis of an epithelial fold The process in which the neural fold is formed. The edges of the neural plate thicken and move up to form a U-shaped structure called the neural groove. http://purl.obolibrary.org/obo/GO_0001865 NK T cell differentiation http://purl.obolibrary.org/obo/GO_0046632 alpha-beta T cell differentiation The process in which a precursor cell type acquires the specialized features of a NK T cell. http://purl.obolibrary.org/obo/GO_0001866 NK T cell proliferation http://purl.obolibrary.org/obo/GO_0051132 NK T cell activation The expansion of a NK T cell population by cell division. http://purl.obolibrary.org/obo/GO_0001873 polysaccharide immune receptor activity http://purl.obolibrary.org/obo/GO_0038187 pattern recognition receptor activity Combining with a polysaccharide and transmitting the signal to initiate an innate immune response. A polysaccharide is a polymer of many (typically more than 10) monosaccharide residues linked glycosidically. http://purl.obolibrary.org/obo/GO_0001885 endothelial cell development http://purl.obolibrary.org/obo/GO_0002064 epithelial cell development The progression of an endothelial cell over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0001886 endothelial cell morphogenesis http://purl.obolibrary.org/obo/GO_0003382 epithelial cell morphogenesis The change in form (cell shape and size) that occurs during the differentiation of an endothelial cell. http://purl.obolibrary.org/obo/GO_0001889 liver development http://purl.obolibrary.org/obo/GO_0048732 gland development The process whose specific outcome is the progression of the liver over time, from its formation to the mature structure. The liver is an exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes. http://purl.obolibrary.org/obo/GO_0001890 placenta development http://purl.obolibrary.org/obo/GO_0048513 animal organ development The process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin. http://purl.obolibrary.org/obo/GO_0001892 embryonic placenta development http://purl.obolibrary.org/obo/GO_0048568 embryonic organ development The embryonically driven process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin. http://purl.obolibrary.org/obo/GO_0001893 maternal placenta development http://purl.obolibrary.org/obo/GO_0060135 maternal process involved in female pregnancy Maternally driven process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin. http://purl.obolibrary.org/obo/GO_0001894 tissue homeostasis http://purl.obolibrary.org/obo/GO_0060249 anatomical structure homeostasis A homeostatic process involved in the maintenance of an internal steady state within a defined tissue of an organism, including control of cellular proliferation and death and control of metabolic function. http://purl.obolibrary.org/obo/GO_0001906 cell killing http://purl.obolibrary.org/obo/GO_0009987 cellular process Any process in an organism that results in the killing of its own cells or those of another organism, including in some cases the death of the other organism. Killing here refers to the induction of death in one cell by another cell, not cell-autonomous death due to internal or other environmental conditions. http://purl.obolibrary.org/obo/GO_0001909 leukocyte mediated cytotoxicity http://purl.obolibrary.org/obo/GO_0002443 leukocyte mediated immunity The directed killing of a target cell by a leukocyte. http://purl.obolibrary.org/obo/GO_0001910 regulation of leukocyte mediated cytotoxicity http://purl.obolibrary.org/obo/GO_0031341 regulation of cell killing Any process that modulates the frequency, rate, or extent of leukocyte mediated cytotoxicity. http://purl.obolibrary.org/obo/GO_0001911 negative regulation of leukocyte mediated cytotoxicity http://purl.obolibrary.org/obo/GO_0031342 negative regulation of cell killing Any process that stops, prevents, or reduces the rate of leukocyte mediated cytotoxicity. http://purl.obolibrary.org/obo/GO_0001912 positive regulation of leukocyte mediated cytotoxicity http://purl.obolibrary.org/obo/GO_0031343 positive regulation of cell killing Any process that activates or increases the frequency, rate or extent of leukocyte mediated cytotoxicity. http://purl.obolibrary.org/obo/GO_0001913 T cell mediated cytotoxicity http://purl.obolibrary.org/obo/GO_0002456 T cell mediated immunity The directed killing of a target cell by a T cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors. http://purl.obolibrary.org/obo/GO_0001914 regulation of T cell mediated cytotoxicity http://purl.obolibrary.org/obo/GO_0002709 regulation of T cell mediated immunity Any process that modulates the frequency, rate, or extent of T cell mediated cytotoxicity. http://purl.obolibrary.org/obo/GO_0001915 negative regulation of T cell mediated cytotoxicity http://purl.obolibrary.org/obo/GO_0002710 negative regulation of T cell mediated immunity Any process that stops, prevents, or reduces the rate of T cell mediated cytotoxicity. http://purl.obolibrary.org/obo/GO_0001916 positive regulation of T cell mediated cytotoxicity http://purl.obolibrary.org/obo/GO_0002711 positive regulation of T cell mediated immunity Any process that activates or increases the frequency, rate or extent of T cell mediated cytotoxicity. http://purl.obolibrary.org/obo/GO_0001922 B-1 B cell homeostasis http://purl.obolibrary.org/obo/GO_0001782 B cell homeostasis The process of regulating the proliferation and elimination of B cells of the B-1 subset such that the total number of B-1 B cells within a whole or part of an organism is stable over time in the absence of an outside stimulus. B-1 B cells are a distinct subset of B cells characterized as being CD5 positive, found predominantly in the peritoneum, pleural cavities, and spleen, and enriched for self-reactivity. http://purl.obolibrary.org/obo/GO_0001923 B-1 B cell differentiation http://purl.obolibrary.org/obo/GO_0002335 mature B cell differentiation The process in which a hemopoietic stem cell acquires the specialized features of a B-1 B cell. B-1 B cells are a distinct subset of B cells characterized as being CD5 positive, found predominantly in the peritoneum, pleural cavities, and spleen, and enriched for self-reactivity. http://purl.obolibrary.org/obo/GO_0001924 regulation of B-1 B cell differentiation http://purl.obolibrary.org/obo/GO_0045577 regulation of B cell differentiation Any process that modulates the frequency, rate, or extent of B-1 B cell differentiation. B-1 B cells are a distinct subset of B cells characterized as being CD5 positive, found predominantly in the peritoneum, pleural cavities, and spleen, and enriched for self-reactivity. http://purl.obolibrary.org/obo/GO_0001925 negative regulation of B-1 B cell differentiation http://purl.obolibrary.org/obo/GO_0045578 negative regulation of B cell differentiation Any process that stops, prevents, or reduces the rate of B-1 B cell differentiation. http://purl.obolibrary.org/obo/GO_0001926 positive regulation of B-1 B cell differentiation http://purl.obolibrary.org/obo/GO_0045579 positive regulation of B cell differentiation Any process that activates or increases the frequency, rate or extent of B-1 B cell differentiation. http://purl.obolibrary.org/obo/GO_0001935 endothelial cell proliferation http://purl.obolibrary.org/obo/GO_0050673 epithelial cell proliferation The multiplication or reproduction of endothelial cells, resulting in the expansion of a cell population. Endothelial cells are thin flattened cells which line the inside surfaces of body cavities, blood vessels, and lymph vessels, making up the endothelium. http://purl.obolibrary.org/obo/GO_0001936 regulation of endothelial cell proliferation http://purl.obolibrary.org/obo/GO_0050678 regulation of epithelial cell proliferation Any process that modulates the frequency, rate, or extent of endothelial cell proliferation. http://purl.obolibrary.org/obo/GO_0001937 negative regulation of endothelial cell proliferation http://purl.obolibrary.org/obo/GO_0050680 negative regulation of epithelial cell proliferation Any process that stops, prevents, or reduces the rate or extent of endothelial cell proliferation. http://purl.obolibrary.org/obo/GO_0001938 positive regulation of endothelial cell proliferation http://purl.obolibrary.org/obo/GO_0050679 positive regulation of epithelial cell proliferation Any process that activates or increases the rate or extent of endothelial cell proliferation. http://purl.obolibrary.org/obo/GO_0001940 male pronucleus http://purl.obolibrary.org/obo/GO_0045120 pronucleus The pronucleus originating from the spermatozoa that was involved in fertilization. http://purl.obolibrary.org/obo/GO_0001941 postsynaptic membrane organization http://purl.obolibrary.org/obo/GO_0061024 membrane organization A process which results in the assembly, arrangement of constituent parts, or disassembly of a postsynaptic membrane, the specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). http://purl.obolibrary.org/obo/GO_0001942 hair follicle development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the hair follicle over time, from its formation to the mature structure. A hair follicle is a tube-like opening in the epidermis where the hair shaft develops and into which the sebaceous glands open. http://purl.obolibrary.org/obo/GO_0001944 vasculature development http://purl.obolibrary.org/obo/GO_0048731 system development The process whose specific outcome is the progression of the vasculature over time, from its formation to the mature structure. The vasculature is an interconnected tubular multi-tissue structure that contains fluid that is actively transported around the organism. http://purl.obolibrary.org/obo/GO_0001945 lymph vessel development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of a lymph vessel over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0001946 lymphangiogenesis http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis Lymph vessel formation when new vessels emerge from the proliferation of pre-existing vessels. http://purl.obolibrary.org/obo/GO_0001949 sebaceous gland cell differentiation http://purl.obolibrary.org/obo/GO_0009913 epidermal cell differentiation The process in which a relatively unspecialized epidermal cell acquires the specialized features of a sebaceous gland cell. http://purl.obolibrary.org/obo/GO_0001955 blood vessel maturation http://purl.obolibrary.org/obo/GO_0071695 anatomical structure maturation A developmental process, independent of morphogenetic (shape) change, that is required for a blood vessel to attain its fully functional state. http://purl.obolibrary.org/obo/GO_0001956 positive regulation of neurotransmitter secretion http://purl.obolibrary.org/obo/GO_1903532 positive regulation of secretion by cell Any process that activates or increases the frequency, rate or extent of the regulated release of a neurotransmitter. http://purl.obolibrary.org/obo/GO_0001957 intramembranous ossification http://purl.obolibrary.org/obo/GO_0036072 direct ossification Direct ossification that occurs within mesenchyme or an accumulation of relatively unspecialized cells. http://purl.obolibrary.org/obo/GO_0001958 endochondral ossification http://purl.obolibrary.org/obo/GO_0036075 replacement ossification Replacement ossification wherein bone tissue replaces cartilage. http://purl.obolibrary.org/obo/GO_0001959 regulation of cytokine-mediated signaling pathway http://purl.obolibrary.org/obo/GO_0060759 regulation of response to cytokine stimulus Any process that modulates the frequency, rate or extent of the cytokine mediated signaling pathway. http://purl.obolibrary.org/obo/GO_0001960 negative regulation of cytokine-mediated signaling pathway http://purl.obolibrary.org/obo/GO_0060761 negative regulation of response to cytokine stimulus Any process that stops, prevents, or reduces the frequency, rate or extent of the cytokine mediated signaling pathway. http://purl.obolibrary.org/obo/GO_0001961 positive regulation of cytokine-mediated signaling pathway http://purl.obolibrary.org/obo/GO_0060760 positive regulation of response to cytokine stimulus Any process that activates or increases the frequency, rate or extent of a cytokine mediated signaling pathway. http://purl.obolibrary.org/obo/GO_0001963 synaptic transmission, dopaminergic http://purl.obolibrary.org/obo/GO_0007268 chemical synaptic transmission The vesicular release of dopamine. from a presynapse, across a chemical synapse, the subsequent activation of dopamine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse. http://purl.obolibrary.org/obo/GO_0001974 blood vessel remodeling http://purl.obolibrary.org/obo/GO_0048771 tissue remodeling The reorganization or renovation of existing blood vessels. http://purl.obolibrary.org/obo/GO_0001976 nervous system process involved in regulation of systemic arterial blood pressure http://purl.obolibrary.org/obo/GO_0050877 nervous system process The regulation of blood pressure mediated by detection of stimuli and a neurological response. http://purl.obolibrary.org/obo/GO_0001990 regulation of systemic arterial blood pressure by hormone http://purl.obolibrary.org/obo/GO_0050886 endocrine process The process in which hormones modulate the force with which blood passes through the circulatory system. A hormone is one of a group of substances formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells, in the same organism, upon which they have a specific regulatory action. http://purl.obolibrary.org/obo/GO_0001991 regulation of systemic arterial blood pressure by circulatory renin-angiotensin http://purl.obolibrary.org/obo/GO_0003081 regulation of systemic arterial blood pressure by renin-angiotensin The process in which angiotensinogen metabolites in the bloodstream modulate the force with which blood passes through the circulatory system. The process begins when renin is released and cleaves angiotensinogen. http://purl.obolibrary.org/obo/GO_0001992 regulation of systemic arterial blood pressure by vasopressin http://purl.obolibrary.org/obo/GO_0001990 regulation of systemic arterial blood pressure by hormone The regulation of blood pressure mediated by the signaling molecule vasopressin. Vasopressin is produced in the hypothalamus, and affects vasoconstriction, and renal water transport. http://purl.obolibrary.org/obo/GO_0001999 renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure http://purl.obolibrary.org/obo/GO_0003071 renal system process involved in regulation of systemic arterial blood pressure The physiological response of the kidneys to a decrease in blood flow. http://purl.obolibrary.org/obo/GO_0002001 renin secretion into blood stream http://purl.obolibrary.org/obo/GO_0023061 signal release The regulated release of renin into the blood stream by juxtoglomerular cells. http://purl.obolibrary.org/obo/GO_0002009 morphogenesis of an epithelium http://purl.obolibrary.org/obo/GO_0048729 tissue morphogenesis The process in which the anatomical structures of epithelia are generated and organized. An epithelium consists of closely packed cells arranged in one or more layers, that covers the outer surfaces of the body or lines any internal cavity or tube. http://purl.obolibrary.org/obo/GO_0002011 morphogenesis of an epithelial sheet http://purl.obolibrary.org/obo/GO_0002009 morphogenesis of an epithelium The process in which the anatomical structures of an epithelial sheet are generated and organized. An epithelial sheet is a flat surface consisting of closely packed epithelial cells. http://purl.obolibrary.org/obo/GO_0002027 regulation of heart rate http://purl.obolibrary.org/obo/GO_0065008 regulation of biological quality Any process that modulates the frequency or rate of heart contraction. http://purl.obolibrary.org/obo/GO_0002028 regulation of sodium ion transport http://purl.obolibrary.org/obo/GO_0010959 regulation of metal ion transport Any process that modulates the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0002036 regulation of L-glutamate import across plasma membrane http://purl.obolibrary.org/obo/GO_0010958 regulation of amino acid import across plasma membrane Any process that modulates the frequency, rate or extent of L-glutamate import into a cell. http://purl.obolibrary.org/obo/GO_0002037 negative regulation of L-glutamate import across plasma membrane http://purl.obolibrary.org/obo/GO_0034763 negative regulation of transmembrane transport Any process that stops, prevents or reduces the frequency, rate or extent of L-glutamate import into a cell. http://purl.obolibrary.org/obo/GO_0002038 positive regulation of L-glutamate import across plasma membrane http://purl.obolibrary.org/obo/GO_0034764 positive regulation of transmembrane transport Any process that activates or increases the frequency, rate or extent of L-glutamate import into a cell. http://purl.obolibrary.org/obo/GO_0002052 positive regulation of neuroblast proliferation http://purl.obolibrary.org/obo/GO_2000179 positive regulation of neural precursor cell proliferation Any process that activates or increases the rate of neuroblast proliferation. http://purl.obolibrary.org/obo/GO_0002053 positive regulation of mesenchymal cell proliferation http://purl.obolibrary.org/obo/GO_0010464 regulation of mesenchymal cell proliferation The process of activating or increasing the rate or extent of mesenchymal cell proliferation. Mesenchymal cells are loosely organized embryonic cells. http://purl.obolibrary.org/obo/GO_0002062 chondrocyte differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte. A chondrocyte is a polymorphic cell that forms cartilage. http://purl.obolibrary.org/obo/GO_0002063 chondrocyte development http://purl.obolibrary.org/obo/GO_0048468 cell development The process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate. http://purl.obolibrary.org/obo/GO_0002064 epithelial cell development http://purl.obolibrary.org/obo/GO_0048468 cell development The process whose specific outcome is the progression of an epithelial cell over time, from its formation to the mature structure. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface. http://purl.obolibrary.org/obo/GO_0002065 columnar/cuboidal epithelial cell differentiation http://purl.obolibrary.org/obo/GO_0030855 epithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a columnar/cuboidal epithelial cell. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube. http://purl.obolibrary.org/obo/GO_0002066 columnar/cuboidal epithelial cell development http://purl.obolibrary.org/obo/GO_0002064 epithelial cell development The process whose specific outcome is the progression of a columnar/cuboidal epithelial cell over time, from its formation to the mature structure. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube. http://purl.obolibrary.org/obo/GO_0002067 glandular epithelial cell differentiation http://purl.obolibrary.org/obo/GO_0002065 columnar/cuboidal epithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a glandular epithelial cell. A glandular epithelial cell is a columnar/cuboidal epithelial cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland. http://purl.obolibrary.org/obo/GO_0002068 glandular epithelial cell development http://purl.obolibrary.org/obo/GO_0002066 columnar/cuboidal epithelial cell development The process whose specific outcome is the progression of a glandular epithelial cell over time, from its formation to the mature structure. A glandular epithelial cell is a columnar/cuboidal epithelial cell is a cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland. http://purl.obolibrary.org/obo/GO_0002069 columnar/cuboidal epithelial cell maturation http://purl.obolibrary.org/obo/GO_0002070 epithelial cell maturation The developmental process, independent of morphogenetic (shape) change, that is required for a columna/cuboidal epithelial cell to attain its fully functional state. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube. http://purl.obolibrary.org/obo/GO_0002070 epithelial cell maturation http://purl.obolibrary.org/obo/GO_0048469 cell maturation The developmental process, independent of morphogenetic (shape) change, that is required for an epithelial cell to attain its fully functional state. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface. http://purl.obolibrary.org/obo/GO_0002071 glandular epithelial cell maturation http://purl.obolibrary.org/obo/GO_0002069 columnar/cuboidal epithelial cell maturation The developmental process, independent of morphogenetic (shape) change, that is required for a glandular epithelial cell to attain its fully functional state. A glandular epithelial cell is a columnar/cuboidal epithelial cell is a cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland. http://purl.obolibrary.org/obo/GO_0002072 optic cup morphogenesis involved in camera-type eye development http://purl.obolibrary.org/obo/GO_0016331 morphogenesis of embryonic epithelium The invagination of the optic vesicle to form two-walled indentations, the optic cups, that will go on to form the retina. This process begins with the optic vesicle becoming a two-walled structure and its subsequent shape changes. It does not include the fate commitment of cells to become the pigmented retina and the neural retina. An example of this process is found in Mus musculus. http://purl.obolibrary.org/obo/GO_0002074 extraocular skeletal muscle development http://purl.obolibrary.org/obo/GO_0060538 skeletal muscle organ development The process whose specific outcome is the progression of the extraocular skeletal muscle over time, from its formation to the mature structure. The extraocular muscle is derived from cranial mesoderm and controls eye movements. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. An example of this process is found in Mus musculus. http://purl.obolibrary.org/obo/GO_0002076 osteoblast development http://purl.obolibrary.org/obo/GO_0048468 cell development The process whose specific outcome is the progression of an osteoblast over time, from its formation to the mature structure. Osteoblast development does not include the steps involved in committing a cranial neural crest cell or an osteoprogenitor cell to an osteoblast fate. An osteoblast is a cell that gives rise to bone. http://purl.obolibrary.org/obo/GO_0002080 acrosomal membrane http://purl.obolibrary.org/obo/GO_0030667 secretory granule membrane The membrane that surrounds the acrosomal lumen. The acrosome is a special type of lysosome in the head of a spermatozoon that contains acid hydrolases and is concerned with the breakdown of the outer membrane of the ovum during fertilization. http://purl.obolibrary.org/obo/GO_0002085 inhibition of neuroepithelial cell differentiation http://purl.obolibrary.org/obo/GO_0048505 regulation of timing of cell differentiation Any process that prevents the activation of neuroepithelial cell differentiation. Neuroepithelial cell differentiation is the process in which epiblast cells acquire specialized features of neuroepithelial cells. http://purl.obolibrary.org/obo/GO_0002087 regulation of respiratory gaseous exchange by nervous system process http://purl.obolibrary.org/obo/GO_0050877 nervous system process A process carried out by the nervous system that is required for the proper control of respiratory gaseous exchange. This process occurs in the respiratory center of the brain in vertebrates. http://purl.obolibrary.org/obo/GO_0002088 lens development in camera-type eye http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the lens over time, from its formation to the mature structure. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus. http://purl.obolibrary.org/obo/GO_0002089 lens morphogenesis in camera-type eye http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structures of the lens are generated and organized. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus. http://purl.obolibrary.org/obo/GO_0002093 auditory receptor cell morphogenesis http://purl.obolibrary.org/obo/GO_0048667 cell morphogenesis involved in neuron differentiation Any process that alters the size or shape of an auditory receptor cell. http://purl.obolibrary.org/obo/GO_0002158 osteoclast proliferation http://purl.obolibrary.org/obo/GO_0070661 leukocyte proliferation The multiplication or reproduction of osteoclasts, resulting in the expansion of an osteoclast cell population. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue, which typically differentiates from monocytes. http://purl.obolibrary.org/obo/GO_0002159 desmosome assembly http://purl.obolibrary.org/obo/GO_0007043 cell-cell junction assembly A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a desmosome. A desmosome is a patch-like intercellular junction found in vertebrate tissues, consisting of parallel zones of two cell membranes, separated by an space of 25-35 nm, and having dense fibrillar plaques in the subjacent cytoplasm. http://purl.obolibrary.org/obo/GO_0002164 larval development http://purl.obolibrary.org/obo/GO_0009791 post-embryonic development The process whose specific outcome is the progression of the larva over time, from its formation to the mature structure. The larva is the early, immature form of an that at birth or hatching is fundamentally unlike its parent and must metamorphose before assuming the adult characters. http://purl.obolibrary.org/obo/GO_0002165 instar larval or pupal development http://purl.obolibrary.org/obo/GO_0009791 post-embryonic development The process whose specific outcome is the progression of the instar larva or pupa over time, from its formation to the mature structure. An example of this process is found in Drosophila melanogaster. http://purl.obolibrary.org/obo/GO_0002176 male germ cell proliferation http://purl.obolibrary.org/obo/GO_0036093 germ cell proliferation The multiplication or reproduction of male germ cells, resulting in the expansion of a cell population. http://purl.obolibrary.org/obo/GO_0002181 cytoplasmic translation http://purl.obolibrary.org/obo/GO_0006412 translation The chemical reactions and pathways resulting in the formation of a protein in the cytoplasm. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein. http://purl.obolibrary.org/obo/GO_0002182 cytoplasmic translational elongation http://purl.obolibrary.org/obo/GO_0006414 translational elongation The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis in the cytoplasm. http://purl.obolibrary.org/obo/GO_0002183 cytoplasmic translational initiation http://purl.obolibrary.org/obo/GO_0006413 translational initiation The process preceding formation of the peptide bond between the first two amino acids of a protein in the cytoplasm. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA. http://purl.obolibrary.org/obo/GO_0002184 cytoplasmic translational termination http://purl.obolibrary.org/obo/GO_0006415 translational termination The process resulting in the release of a polypeptide chain from the ribosome in the cytoplasm, usually in response to a termination codon. http://purl.obolibrary.org/obo/GO_0002200 somatic diversification of immune receptors http://purl.obolibrary.org/obo/GO_0002376 immune system process The somatic process allowing for the production of immune receptors whose specificity is not encoded in the germline genomic sequences. http://purl.obolibrary.org/obo/GO_0002204 somatic recombination of immunoglobulin genes involved in immune response http://purl.obolibrary.org/obo/GO_0016447 somatic recombination of immunoglobulin gene segments The process in which immunoglobulin genes are formed through recombination of the germline genetic elements, also known as immunoglobulin gene segments, within a single locus following the induction of and contributing to an immune response. http://purl.obolibrary.org/obo/GO_0002208 somatic diversification of immunoglobulins involved in immune response http://purl.obolibrary.org/obo/GO_0016445 somatic diversification of immunoglobulins The somatic process that results in the generation of sequence diversity of immunoglobulins after induction, and contributes to an immune response. http://purl.obolibrary.org/obo/GO_0002213 defense response to insect http://purl.obolibrary.org/obo/GO_0051707 response to other organism A response to protect an organism from a directly detected or perceived external threat from an insect or insects to that organism. http://purl.obolibrary.org/obo/GO_0002215 defense response to nematode http://purl.obolibrary.org/obo/GO_0051707 response to other organism A response to protect an organism from a directly detected or perceived external threat from a nematode or nematodes, which results in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack. http://purl.obolibrary.org/obo/GO_0002225 positive regulation of antimicrobial peptide production http://purl.obolibrary.org/obo/GO_0002784 regulation of antimicrobial peptide production Any process that activates or increases the frequency, rate, or extent of antimicrobial peptide production. http://purl.obolibrary.org/obo/GO_0002227 innate immune response in mucosa http://purl.obolibrary.org/obo/GO_0045087 innate immune response Any process of the innate immune response that takes place in the mucosal tissues. http://purl.obolibrary.org/obo/GO_0002228 natural killer cell mediated immunity http://purl.obolibrary.org/obo/GO_0045087 innate immune response The promotion of an immune response by natural killer cells through direct recognition of target cells or through the release of cytokines. http://purl.obolibrary.org/obo/GO_0002232 leukocyte chemotaxis involved in inflammatory response http://purl.obolibrary.org/obo/GO_0030595 leukocyte chemotaxis The movement of an immune cell in response to an external stimulus contributing to an inflammatory response. http://purl.obolibrary.org/obo/GO_0002233 leukocyte chemotaxis involved in immune response http://purl.obolibrary.org/obo/GO_0030595 leukocyte chemotaxis The movement of an immune cell in response to an external stimulus a part of an immune response. http://purl.obolibrary.org/obo/GO_0002244 hematopoietic progenitor cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which precursor cell type acquires the specialized features of a hematopoietic progenitor cell, a class of cell types including myeloid progenitor cells and lymphoid progenitor cells. http://purl.obolibrary.org/obo/GO_0002246 wound healing involved in inflammatory response http://purl.obolibrary.org/obo/GO_0042060 wound healing The series of events that restore integrity to damaged tissue that contribute to an inflammatory response. http://purl.obolibrary.org/obo/GO_0002249 lymphocyte anergy http://purl.obolibrary.org/obo/GO_0002507 tolerance induction Any process contributing to lymphocyte anergy, a state of functional inactivation. http://purl.obolibrary.org/obo/GO_0002250 adaptive immune response http://purl.obolibrary.org/obo/GO_0006955 immune response An immune response mediated by cells expressing specific receptors for antigens produced through a somatic diversification process, and allowing for an enhanced secondary response to subsequent exposures to the same antigen (immunological memory). http://purl.obolibrary.org/obo/GO_0002251 organ or tissue specific immune response http://purl.obolibrary.org/obo/GO_0006955 immune response An immune response taking place in an organ or tissues such as the liver, brain, mucosa, or nervous system tissues. http://purl.obolibrary.org/obo/GO_0002252 immune effector process http://purl.obolibrary.org/obo/GO_0002376 immune system process Any process of the immune system that executes a component of an immune response. An effector immune process takes place after its activation. http://purl.obolibrary.org/obo/GO_0002260 lymphocyte homeostasis http://purl.obolibrary.org/obo/GO_0001776 leukocyte homeostasis The process of regulating the proliferation and elimination of lymphocytes such that the total number of lymphocytes within a whole or part of an organism is stable over time in the absence of an outside stimulus. http://purl.obolibrary.org/obo/GO_0002262 myeloid cell homeostasis http://purl.obolibrary.org/obo/GO_0048872 homeostasis of number of cells The process of regulating the proliferation and elimination of myeloid cells such that the total number of myeloid cells within a whole or part of an organism is stable over time in the absence of an outside stimulus. http://purl.obolibrary.org/obo/GO_0002263 cell activation involved in immune response http://purl.obolibrary.org/obo/GO_0002252 immune effector process A change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response. http://purl.obolibrary.org/obo/GO_0002264 endothelial cell activation involved in immune response http://purl.obolibrary.org/obo/GO_0042118 endothelial cell activation A change in the morphology or behavior of an endothelial cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response. http://purl.obolibrary.org/obo/GO_0002265 astrocyte activation involved in immune response http://purl.obolibrary.org/obo/GO_0048143 astrocyte activation A change in the morphology or behavior of an astrocyte resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response. http://purl.obolibrary.org/obo/GO_0002266 follicular dendritic cell activation http://purl.obolibrary.org/obo/GO_0045321 leukocyte activation A change in the morphology or behavior of a follicular dendritic cell resulting from exposure to an activating factor such as a cellular or soluble ligand. http://purl.obolibrary.org/obo/GO_0002268 follicular dendritic cell differentiation http://purl.obolibrary.org/obo/GO_0097028 dendritic cell differentiation The process in which a relatively unspecialized precursor cell acquires the specialized features of a follicular dendritic cell. http://purl.obolibrary.org/obo/GO_0002269 leukocyte activation involved in inflammatory response http://purl.obolibrary.org/obo/GO_0045321 leukocyte activation A change in the morphology or behavior of a leukocyte resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an inflammatory response. http://purl.obolibrary.org/obo/GO_0002270 plasmacytoid dendritic cell activation http://purl.obolibrary.org/obo/GO_0045321 leukocyte activation A change in the morphology or behavior of a plasmacytoid dendritic cell resulting from exposure to an activating factor such as a cellular or soluble ligand. http://purl.obolibrary.org/obo/GO_0002273 plasmacytoid dendritic cell differentiation http://purl.obolibrary.org/obo/GO_0097028 dendritic cell differentiation The process in which a relatively unspecialized hemopoietic precursor cell acquires the specialized features of a plasmacytoid dendritic cell. http://purl.obolibrary.org/obo/GO_0002274 myeloid leukocyte activation http://purl.obolibrary.org/obo/GO_0045321 leukocyte activation A change in the morphology or behavior of a myeloid leukocyte resulting from exposure to an activating factor such as a cellular or soluble ligand. http://purl.obolibrary.org/obo/GO_0002275 myeloid cell activation involved in immune response http://purl.obolibrary.org/obo/GO_0002366 leukocyte activation involved in immune response A change in the morphology or behavior of a myeloid cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response. http://purl.obolibrary.org/obo/GO_0002276 basophil activation involved in immune response http://purl.obolibrary.org/obo/GO_0045575 basophil activation A change in morphology and behavior of a basophil resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the basophil has specifically bound via IgE bound to Fc-epsilonRI receptors, leading to the initiation or perpetuation of an immune response. http://purl.obolibrary.org/obo/GO_0002277 myeloid dendritic cell activation involved in immune response http://purl.obolibrary.org/obo/GO_0002275 myeloid cell activation involved in immune response The change in morphology and behavior of a myeloid dendritic cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response. http://purl.obolibrary.org/obo/GO_0002278 eosinophil activation involved in immune response http://purl.obolibrary.org/obo/GO_0043307 eosinophil activation The change in morphology and behavior of a eosinophil resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response. http://purl.obolibrary.org/obo/GO_0002279 mast cell activation involved in immune response http://purl.obolibrary.org/obo/GO_0045576 mast cell activation The change in morphology and behavior of a mast cell resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the mast cell has specifically bound via IgE bound to Fc-epsilonRI receptors, leading to the initiation or perpetuation of an immune response. http://purl.obolibrary.org/obo/GO_0002280 monocyte activation involved in immune response http://purl.obolibrary.org/obo/GO_0042117 monocyte activation The change in morphology and behavior of a monocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response. http://purl.obolibrary.org/obo/GO_0002281 macrophage activation involved in immune response http://purl.obolibrary.org/obo/GO_0042116 macrophage activation A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response. http://purl.obolibrary.org/obo/GO_0002282 microglial cell activation involved in immune response http://purl.obolibrary.org/obo/GO_0002281 macrophage activation involved in immune response The change in morphology and behavior of a microglial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response. http://purl.obolibrary.org/obo/GO_0002283 neutrophil activation involved in immune response http://purl.obolibrary.org/obo/GO_0042119 neutrophil activation The change in morphology and behavior of a neutrophil resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response. http://purl.obolibrary.org/obo/GO_0002285 lymphocyte activation involved in immune response http://purl.obolibrary.org/obo/GO_0046649 lymphocyte activation A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response. http://purl.obolibrary.org/obo/GO_0002286 T cell activation involved in immune response http://purl.obolibrary.org/obo/GO_0042110 T cell activation The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response. http://purl.obolibrary.org/obo/GO_0002287 alpha-beta T cell activation involved in immune response http://purl.obolibrary.org/obo/GO_0046631 alpha-beta T cell activation The change in morphology and behavior of an alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response. http://purl.obolibrary.org/obo/GO_0002292 T cell differentiation involved in immune response http://purl.obolibrary.org/obo/GO_0030217 T cell differentiation The process in which an antigenically naive T cell acquires the specialized features of an effector, regulatory, or memory T cell as part of an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells. http://purl.obolibrary.org/obo/GO_0002299 alpha-beta intraepithelial T cell differentiation http://purl.obolibrary.org/obo/GO_0046632 alpha-beta T cell differentiation The process in which a precursor cell type acquires the specialized features of an alpha-beta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways. http://purl.obolibrary.org/obo/GO_0002300 CD8-positive, alpha-beta intraepithelial T cell differentiation http://purl.obolibrary.org/obo/GO_0043374 CD8-positive, alpha-beta T cell differentiation The process in which a precursor cell type acquires the specialized features of a CD8-positive, alpha-beta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways. http://purl.obolibrary.org/obo/GO_0002301 CD4-positive, alpha-beta intraepithelial T cell differentiation http://purl.obolibrary.org/obo/GO_0043367 CD4-positive, alpha-beta T cell differentiation The process in which a precursor cell type acquires the specialized features of a CD4-positive, alpha-beta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways. http://purl.obolibrary.org/obo/GO_0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response http://purl.obolibrary.org/obo/GO_0043374 CD8-positive, alpha-beta T cell differentiation The process in which an antigenically naive CD8-positive, alpha-beta T cell acquires the specialized features of an effector, regulatory, or memory T cell as part of an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells. http://purl.obolibrary.org/obo/GO_0002304 gamma-delta intraepithelial T cell differentiation http://purl.obolibrary.org/obo/GO_0042492 gamma-delta T cell differentiation The process in which a precursor cell type acquires the specialized features of a gamma-delta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways. http://purl.obolibrary.org/obo/GO_0002305 CD8-positive, gamma-delta intraepithelial T cell differentiation http://purl.obolibrary.org/obo/GO_0002304 gamma-delta intraepithelial T cell differentiation The process in which a precursor cell type acquires the specialized features of a CD8-positive, gamma-delta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways. http://purl.obolibrary.org/obo/GO_0002306 CD4-positive gamma-delta intraepithelial T cell differentiation http://purl.obolibrary.org/obo/GO_0002304 gamma-delta intraepithelial T cell differentiation The process in which a precursor cell type acquires the specialized features of a CD4-positive, gamma-delta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways. http://purl.obolibrary.org/obo/GO_0002307 CD8-positive, alpha-beta regulatory T cell differentiation http://purl.obolibrary.org/obo/GO_0045066 regulatory T cell differentiation The process in which a precursor cell type acquires the specialized features of a CD8-positive, alpha-beta regulatory T cell. http://purl.obolibrary.org/obo/GO_0002308 CD8-positive, alpha-beta cytotoxic T cell differentiation http://purl.obolibrary.org/obo/GO_0045065 cytotoxic T cell differentiation The process in which a precursor cell type acquires the specialized features of a CD8-positive, alpha-beta cytotoxic T cell. http://purl.obolibrary.org/obo/GO_0002309 T cell proliferation involved in immune response http://purl.obolibrary.org/obo/GO_0042098 T cell proliferation The expansion of a T cell population by cell division as part of an immune response. http://purl.obolibrary.org/obo/GO_0002312 B cell activation involved in immune response http://purl.obolibrary.org/obo/GO_0042113 B cell activation The change in morphology and behavior of a mature or immature B cell during an immune response, resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. http://purl.obolibrary.org/obo/GO_0002313 mature B cell differentiation involved in immune response http://purl.obolibrary.org/obo/GO_0002335 mature B cell differentiation The process in which a naive B cell acquires the specialized features of a mature or memory B cell during an immune response. http://purl.obolibrary.org/obo/GO_0002314 germinal center B cell differentiation http://purl.obolibrary.org/obo/GO_0002313 mature B cell differentiation involved in immune response The process in which a B cell in the spleen acquires the specialized features of a germinal center B cell. Germinal center B cells are rapidly cycling B cells which have downregulated IgD expression and exhibit high levels of binding by peanut agglutinin (PNA). http://purl.obolibrary.org/obo/GO_0002315 marginal zone B cell differentiation http://purl.obolibrary.org/obo/GO_0002313 mature B cell differentiation involved in immune response The process in which a B cell in the spleen acquires the specialized features of a marginal zone B cell. Marginal zone B cells are localized in a distinct anatomical region of the spleen that represents the major antigen-filtering and scavenging area (by specialized macrophages resident there). It appears that they are preselected to express a BCR repertoire similar to B-1 B cells, biased toward bacterial cell wall constituents and senescent self-components (such as oxidized LDL). http://purl.obolibrary.org/obo/GO_0002316 follicular B cell differentiation http://purl.obolibrary.org/obo/GO_0002313 mature B cell differentiation involved in immune response The process in which a B cell in the spleen acquires the specialized features of a follicular B cell. Follicular B cells are major population of mature recirculating B cells in the spleen and are located in the B-cell follicle region. http://purl.obolibrary.org/obo/GO_0002317 plasma cell differentiation http://purl.obolibrary.org/obo/GO_0002313 mature B cell differentiation involved in immune response The process in which a B cell acquires the specialized features of a plasma cell. A plasma cell is a lymphocyte which develops from a B cell and produces high amounts of antibody. http://purl.obolibrary.org/obo/GO_0002318 myeloid progenitor cell differentiation http://purl.obolibrary.org/obo/GO_0002244 hematopoietic progenitor cell differentiation The process in which a precursor cell type acquires the specialized features of a myeloid progenitor cell. Myeloid progenitor cells include progenitor cells for any of the myeloid lineages. http://purl.obolibrary.org/obo/GO_0002319 memory B cell differentiation http://purl.obolibrary.org/obo/GO_0090715 immunological memory formation process The process in which a B cell acquires the specialized features of a memory B cell. Memory B cells are cells that can respond rapidly to antigen re-exposure by production of high-affinity antibody. http://purl.obolibrary.org/obo/GO_0002320 lymphoid progenitor cell differentiation http://purl.obolibrary.org/obo/GO_0002244 hematopoietic progenitor cell differentiation The process in which a precursor cell type acquires the specialized features of a lymphoid progenitor cell. Lymphoid progenitor cells include progenitor cells for any of the lymphoid lineages. http://purl.obolibrary.org/obo/GO_0002321 natural killer cell progenitor differentiation http://purl.obolibrary.org/obo/GO_0002320 lymphoid progenitor cell differentiation The process in which a precursor cell type acquires the specialized features of a natural killer cell progenitor. http://purl.obolibrary.org/obo/GO_0002322 B cell proliferation involved in immune response http://purl.obolibrary.org/obo/GO_0042100 B cell proliferation The expansion of a B cell population by cell division following B cell activation during an immune response. http://purl.obolibrary.org/obo/GO_0002323 natural killer cell activation involved in immune response http://purl.obolibrary.org/obo/GO_0030101 natural killer cell activation The change in morphology and behavior of a natural killer cell resulting from exposure a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response. http://purl.obolibrary.org/obo/GO_0002327 immature B cell differentiation http://purl.obolibrary.org/obo/GO_0030183 B cell differentiation The process in which a precursor cell type acquires the specialized features of an immature B cell. http://purl.obolibrary.org/obo/GO_0002328 pro-B cell differentiation http://purl.obolibrary.org/obo/GO_0002320 lymphoid progenitor cell differentiation The process in which a precursor cell type acquires the specialized features of a pro-B cell. Pro-B cells are the earliest stage of the B cell lineage and undergo heavy chain D and J gene rearrangements, although they are not fully committed. http://purl.obolibrary.org/obo/GO_0002329 pre-B cell differentiation http://purl.obolibrary.org/obo/GO_0002327 immature B cell differentiation The process in which a precursor cell type acquires the specialized features of a pre-B cell. Pre-B cells follow the pro-B cell stage of immature B cell differentiation and undergo rearrangement of heavy chain V, D, and J gene segments. http://purl.obolibrary.org/obo/GO_0002332 transitional stage B cell differentiation http://purl.obolibrary.org/obo/GO_0002327 immature B cell differentiation The process in which immature B cells from the bone marrow become mature B cells in the spleen. Transitional stage B cells are subdivided into transitional one (T1) and transitional two (T2) stages and are short-lived and functionally incompetent. http://purl.obolibrary.org/obo/GO_0002335 mature B cell differentiation http://purl.obolibrary.org/obo/GO_0030183 B cell differentiation The process in which transitional stage B cells acquire the specialized features of mature B cells in the spleen. http://purl.obolibrary.org/obo/GO_0002337 B-1a B cell differentiation http://purl.obolibrary.org/obo/GO_0001923 B-1 B cell differentiation The process in which B cells acquire the specialized features of B-1a B cells. B-1a B cells are B-1 cells that express CD5 and arise from fetal liver precursors. http://purl.obolibrary.org/obo/GO_0002338 B-1b B cell differentiation http://purl.obolibrary.org/obo/GO_0001923 B-1 B cell differentiation The process in which B cells acquire the specialized features of B-1b B cells. B-1b B cells are B-1 cells that do not express CD5. http://purl.obolibrary.org/obo/GO_0002339 B cell selection http://purl.obolibrary.org/obo/GO_0002376 immune system process The process dependent upon B cell antigen receptor signaling in response to self or foreign antigen through which B cells are selected for survival. http://purl.obolibrary.org/obo/GO_0002343 peripheral B cell selection http://purl.obolibrary.org/obo/GO_0002339 B cell selection Any B cell selection process that occurs in the periphery. http://purl.obolibrary.org/obo/GO_0002344 B cell affinity maturation http://purl.obolibrary.org/obo/GO_0002343 peripheral B cell selection The process in which B cells produce antibodies with increased antigen affinity. This is accomplished by somatic hypermutation and selection for B cells which produce higher affinity antibodies to antigen. http://purl.obolibrary.org/obo/GO_0002349 histamine production involved in inflammatory response http://purl.obolibrary.org/obo/GO_0002532 production of molecular mediator involved in inflammatory response The synthesis or release of histamine following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels. http://purl.obolibrary.org/obo/GO_0002351 serotonin production involved in inflammatory response http://purl.obolibrary.org/obo/GO_0002532 production of molecular mediator involved in inflammatory response The synthesis or release of serotonin following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels. http://purl.obolibrary.org/obo/GO_0002358 B cell homeostatic proliferation http://purl.obolibrary.org/obo/GO_0042100 B cell proliferation The non-specific expansion of B cell populations within a whole or part of an organism to reach to a total number of B cells which will then remain stable over time in the absence of an external stimulus. http://purl.obolibrary.org/obo/GO_0002359 B-1 B cell proliferation http://purl.obolibrary.org/obo/GO_0042100 B cell proliferation The expansion of a B-1 B cell by cell division. Follows B cell activation. http://purl.obolibrary.org/obo/GO_0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation http://purl.obolibrary.org/obo/GO_0045066 regulatory T cell differentiation The process in which a precursor cell type acquires the specialized features of a CD4-positive, CD25-positive, alpha-beta regulatory T cell. http://purl.obolibrary.org/obo/GO_0002366 leukocyte activation involved in immune response http://purl.obolibrary.org/obo/GO_0045321 leukocyte activation A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response. http://purl.obolibrary.org/obo/GO_0002367 cytokine production involved in immune response http://purl.obolibrary.org/obo/GO_0002440 production of molecular mediator of immune response The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus contributing to an immune response, resulting in an increase in its intracellular or extracellular levels. http://purl.obolibrary.org/obo/GO_0002368 B cell cytokine production http://purl.obolibrary.org/obo/GO_0019724 B cell mediated immunity Any process that contributes to cytokine production by a B cell. http://purl.obolibrary.org/obo/GO_0002369 T cell cytokine production http://purl.obolibrary.org/obo/GO_0002456 T cell mediated immunity Any process that contributes to cytokine production by a T cell. http://purl.obolibrary.org/obo/GO_0002370 natural killer cell cytokine production http://purl.obolibrary.org/obo/GO_0002367 cytokine production involved in immune response Any process that contributes to cytokine production by a natural killer cell. http://purl.obolibrary.org/obo/GO_0002371 dendritic cell cytokine production http://purl.obolibrary.org/obo/GO_0002443 leukocyte mediated immunity Any process that contributes to cytokine production by a dendritic cell. http://purl.obolibrary.org/obo/GO_0002372 myeloid dendritic cell cytokine production http://purl.obolibrary.org/obo/GO_0061082 myeloid leukocyte cytokine production Any process that contributes to cytokine production by a myeloid dendritic cell. http://purl.obolibrary.org/obo/GO_0002373 plasmacytoid dendritic cell cytokine production http://purl.obolibrary.org/obo/GO_0002371 dendritic cell cytokine production Any process that contributes to cytokine production by a plasmacytoid dendritic cell. http://purl.obolibrary.org/obo/GO_0002376 immune system process http://purl.obolibrary.org/obo/GO_0008150 biological_process Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats. http://purl.obolibrary.org/obo/GO_0002377 immunoglobulin production http://purl.obolibrary.org/obo/GO_0002440 production of molecular mediator of immune response The appearance of immunoglobulin due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. http://purl.obolibrary.org/obo/GO_0002381 immunoglobulin production involved in immunoglobulin-mediated immune response http://purl.obolibrary.org/obo/GO_0002377 immunoglobulin production The appearance of immunoglobulin due to biosynthesis or secretion following a cellular stimulus during an immune response, resulting in an increase in its intracellular or extracellular levels. http://purl.obolibrary.org/obo/GO_0002384 hepatic immune response http://purl.obolibrary.org/obo/GO_0002251 organ or tissue specific immune response An immune response taking place in the liver. http://purl.obolibrary.org/obo/GO_0002385 mucosal immune response http://purl.obolibrary.org/obo/GO_0002251 organ or tissue specific immune response An immune response taking place in mucosal tissues, including those of the intestinal tract, nasal and upper respiratory tract, and genital tract. http://purl.obolibrary.org/obo/GO_0002387 immune response in gut-associated lymphoid tissue http://purl.obolibrary.org/obo/GO_0006955 immune response Immune response taking place in the gut-associated lymphoid tissue (GALT). GALT includes Peyer's patches, appendix, and solitary lymph nodules. http://purl.obolibrary.org/obo/GO_0002388 immune response in Peyer's patch http://purl.obolibrary.org/obo/GO_0002387 immune response in gut-associated lymphoid tissue Immune response taking place in the Peyer's patch, nodular lymphoid structures on the serosal surface of the small intestine. http://purl.obolibrary.org/obo/GO_0002389 tolerance induction in Peyer's patch http://purl.obolibrary.org/obo/GO_0002394 tolerance induction in gut-associated lymphoid tissue Tolerance induction taking place in the Peyer's patches. http://purl.obolibrary.org/obo/GO_0002394 tolerance induction in gut-associated lymphoid tissue http://purl.obolibrary.org/obo/GO_0002401 tolerance induction in mucosal-associated lymphoid tissue Tolerance induction taking place in the gut-associated lymphoid tissue (GALT). http://purl.obolibrary.org/obo/GO_0002395 immune response in nasopharyngeal-associated lymphoid tissue http://purl.obolibrary.org/obo/GO_0002387 immune response in gut-associated lymphoid tissue An immune response taking place in the nasopharyngeal-associated lymphoid tissue (NALT). NALT includes the tonsils and adenoids. http://purl.obolibrary.org/obo/GO_0002396 MHC protein complex assembly http://purl.obolibrary.org/obo/GO_0065003 protein-containing complex assembly The aggregation, arrangement and bonding together of a set of components to form an MHC protein complex. http://purl.obolibrary.org/obo/GO_0002399 MHC class II protein complex assembly http://purl.obolibrary.org/obo/GO_0002396 MHC protein complex assembly The aggregation, arrangement and bonding together of a set of components to form an MHC class II protein complex. http://purl.obolibrary.org/obo/GO_0002400 tolerance induction in nasopharyngeal-associated lymphoid tissue http://purl.obolibrary.org/obo/GO_0002395 immune response in nasopharyngeal-associated lymphoid tissue Tolerance induction taking place in the nasopharyngeal-associated lymphoid tissue (NALT). http://purl.obolibrary.org/obo/GO_0002401 tolerance induction in mucosal-associated lymphoid tissue http://purl.obolibrary.org/obo/GO_0002427 mucosal tolerance induction Tolerance induction taking place in the mucosal-associated lymphoid tissue (MALT). http://purl.obolibrary.org/obo/GO_0002402 B cell tolerance induction in mucosal-associated lymphoid tissue http://purl.obolibrary.org/obo/GO_0002451 peripheral B cell tolerance induction Tolerance induction taking place in the mucosal-associated lymphoid tissue (MALT) mediated by B cells. http://purl.obolibrary.org/obo/GO_0002403 T cell tolerance induction in mucosal-associated lymphoid tissue http://purl.obolibrary.org/obo/GO_0002458 peripheral T cell tolerance induction Tolerance induction taking place in the mucosal-associated lymphoid tissue (MALT) mediated by T cells. http://purl.obolibrary.org/obo/GO_0002407 dendritic cell chemotaxis http://purl.obolibrary.org/obo/GO_0036336 dendritic cell migration The movement of a dendritic cell in response to an external stimulus. http://purl.obolibrary.org/obo/GO_0002408 myeloid dendritic cell chemotaxis http://purl.obolibrary.org/obo/GO_0097529 myeloid leukocyte migration The movement of a myeloid dendritic cell in response to an external stimulus. http://purl.obolibrary.org/obo/GO_0002409 Langerhans cell chemotaxis http://purl.obolibrary.org/obo/GO_0002408 myeloid dendritic cell chemotaxis The movement of a Langerhans cell in response to an external stimulus. http://purl.obolibrary.org/obo/GO_0002410 plasmacytoid dendritic cell chemotaxis http://purl.obolibrary.org/obo/GO_0002407 dendritic cell chemotaxis The movement of a plasmacytoid dendritic cell in response to an external stimulus. http://purl.obolibrary.org/obo/GO_0002427 mucosal tolerance induction http://purl.obolibrary.org/obo/GO_0002462 tolerance induction to nonself antigen Tolerance induction taking place in the mucosal tissues. http://purl.obolibrary.org/obo/GO_0002432 granuloma formation http://purl.obolibrary.org/obo/GO_0002252 immune effector process The formation of nodular inflammatory lesions, usually small or granular, firm, persistent, well-structured, and containing compactly grouped T lymphocytes and modified phagocytes such as epithelioid cells, giant cells, and other macrophages. Granuloma formation represents a chronic inflammatory response initiated by various infectious and noninfectious agents. The center of a granuloma consists of fused macrophages, which can become necrotic. http://purl.obolibrary.org/obo/GO_0002440 production of molecular mediator of immune response http://purl.obolibrary.org/obo/GO_0010467 gene expression The synthesis or release of any molecular mediator of the immune response, resulting in an increase in its intracellular or extracellular levels. http://purl.obolibrary.org/obo/GO_0002441 histamine secretion involved in inflammatory response http://purl.obolibrary.org/obo/GO_0046879 hormone secretion The regulated release of histamine by a cell as part of an inflammatory response. http://purl.obolibrary.org/obo/GO_0002442 serotonin secretion involved in inflammatory response http://purl.obolibrary.org/obo/GO_0001820 serotonin secretion The regulated release of serotonin by a cell as part of an inflammatory response. http://purl.obolibrary.org/obo/GO_0002443 leukocyte mediated immunity http://purl.obolibrary.org/obo/GO_0002252 immune effector process Any process involved in the carrying out of an immune response by a leukocyte. http://purl.obolibrary.org/obo/GO_0002444 myeloid leukocyte mediated immunity http://purl.obolibrary.org/obo/GO_0002443 leukocyte mediated immunity Any process involved in the carrying out of an immune response by a myeloid leukocyte. http://purl.obolibrary.org/obo/GO_0002446 neutrophil mediated immunity http://purl.obolibrary.org/obo/GO_0002444 myeloid leukocyte mediated immunity Any process involved in the carrying out of an immune response by a neutrophil. http://purl.obolibrary.org/obo/GO_0002447 eosinophil mediated immunity http://purl.obolibrary.org/obo/GO_0002444 myeloid leukocyte mediated immunity Any process involved in the carrying out of an immune response by an eosinophil. http://purl.obolibrary.org/obo/GO_0002448 mast cell mediated immunity http://purl.obolibrary.org/obo/GO_0002444 myeloid leukocyte mediated immunity Any process involved in the carrying out of an immune response by a mast cell. http://purl.obolibrary.org/obo/GO_0002449 lymphocyte mediated immunity http://purl.obolibrary.org/obo/GO_0002443 leukocyte mediated immunity Any process involved in the carrying out of an immune response by a lymphocyte. http://purl.obolibrary.org/obo/GO_0002450 B cell antigen processing and presentation http://purl.obolibrary.org/obo/GO_0019882 antigen processing and presentation The process in which a B cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex. http://purl.obolibrary.org/obo/GO_0002451 peripheral B cell tolerance induction http://purl.obolibrary.org/obo/GO_0019724 B cell mediated immunity Tolerance induction of mature B cells in the peripheral lymphoid tissues: the blood, lymph nodes, spleen, and mucosal-associated lymphoid tissue. http://purl.obolibrary.org/obo/GO_0002456 T cell mediated immunity http://purl.obolibrary.org/obo/GO_0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains Any process involved in the carrying out of an immune response by a T cell. http://purl.obolibrary.org/obo/GO_0002457 T cell antigen processing and presentation http://purl.obolibrary.org/obo/GO_0019882 antigen processing and presentation The process in which a T cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex. http://purl.obolibrary.org/obo/GO_0002458 peripheral T cell tolerance induction http://purl.obolibrary.org/obo/GO_0002517 T cell tolerance induction Tolerance induction of T cells in the periphery, in this case, any location in the body other than the thymus. http://purl.obolibrary.org/obo/GO_0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains http://purl.obolibrary.org/obo/GO_0002250 adaptive immune response An immune response mediated by lymphocytes expressing specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of germline gene segments encoding immunoglobulin superfamily domains. Recombined receptors for antigen encoded by immunoglobulin superfamily domains include T cell receptors and immunoglobulins (antibodies) produced by B cells. The first encounter with antigen elicits a primary immune response that is slow and not of great magnitude. T and B cells selected by antigen become activated and undergo clonal expansion. A fraction of antigen-reactive T and B cells become memory cells, whereas others differentiate into effector cells. The memory cells generated during the primary response enable a much faster and stronger secondary immune response upon subsequent exposures to the same antigen (immunological memory). An example of this is the adaptive immune response found in Mus musculus. http://purl.obolibrary.org/obo/GO_0002461 tolerance induction dependent upon immune response http://purl.obolibrary.org/obo/GO_0002507 tolerance induction Tolerance induction dependent upon an immune response, typically a response by a mature T or B cell in the periphery resulting tolerance towards an antigen via induction of anergy, cellular deletion, or regulatory T cell activation. http://purl.obolibrary.org/obo/GO_0002462 tolerance induction to nonself antigen http://purl.obolibrary.org/obo/GO_0002461 tolerance induction dependent upon immune response Tolerance induction in response to nonself antigens. http://purl.obolibrary.org/obo/GO_0002465 peripheral tolerance induction http://purl.obolibrary.org/obo/GO_0002461 tolerance induction dependent upon immune response Tolerance induction in the peripheral lymphoid tissues: blood, lymph nodes, spleen, and mucosal-associated lymphoid tissues. http://purl.obolibrary.org/obo/GO_0002467 germinal center formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process in which germinal centers form. A germinal center is a specialized microenvironment formed when activated B cells enter lymphoid follicles. Germinal centers are the foci for B cell proliferation and somatic hypermutation. http://purl.obolibrary.org/obo/GO_0002468 dendritic cell antigen processing and presentation http://purl.obolibrary.org/obo/GO_0019882 antigen processing and presentation The process in which a dendritic cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex. http://purl.obolibrary.org/obo/GO_0002469 myeloid dendritic cell antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002468 dendritic cell antigen processing and presentation The process in which a myeloid dendritic cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex. http://purl.obolibrary.org/obo/GO_0002470 plasmacytoid dendritic cell antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002468 dendritic cell antigen processing and presentation The process in which a plasmacytoid dendritic cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex. http://purl.obolibrary.org/obo/GO_0002471 monocyte antigen processing and presentation http://purl.obolibrary.org/obo/GO_0019882 antigen processing and presentation The process in which a monocyte expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex. http://purl.obolibrary.org/obo/GO_0002472 macrophage antigen processing and presentation http://purl.obolibrary.org/obo/GO_0019882 antigen processing and presentation The process in which a macrophage expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex. http://purl.obolibrary.org/obo/GO_0002474 antigen processing and presentation of peptide antigen via MHC class I http://purl.obolibrary.org/obo/GO_0048002 antigen processing and presentation of peptide antigen The process in which an antigen-presenting cell expresses a peptide antigen on its cell surface in association with an MHC class I protein complex. Class I here refers to classical class I molecules. http://purl.obolibrary.org/obo/GO_0002478 antigen processing and presentation of exogenous peptide antigen http://purl.obolibrary.org/obo/GO_0048002 antigen processing and presentation of peptide antigen The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC protein complex. The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell. http://purl.obolibrary.org/obo/GO_0002483 antigen processing and presentation of endogenous peptide antigen http://purl.obolibrary.org/obo/GO_0048002 antigen processing and presentation of peptide antigen The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC protein complex. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell. http://purl.obolibrary.org/obo/GO_0002491 antigen processing and presentation of endogenous peptide antigen via MHC class II http://purl.obolibrary.org/obo/GO_0002495 antigen processing and presentation of peptide antigen via MHC class II The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class II protein complex. The peptide antigen is typically, but not always, processed from a whole protein. http://purl.obolibrary.org/obo/GO_0002495 antigen processing and presentation of peptide antigen via MHC class II http://purl.obolibrary.org/obo/GO_0048002 antigen processing and presentation of peptide antigen The process in which an antigen-presenting cell expresses a peptide antigen on its cell surface in association with an MHC class II protein complex. The peptide antigen is typically, but not always, processed from a whole protein. http://purl.obolibrary.org/obo/GO_0002496 proteolysis associated with antigen processing and presentation http://purl.obolibrary.org/obo/GO_0006508 proteolysis The hydrolysis of a peptide bond or bonds within a protein contributing to antigen processing and presentation. http://purl.obolibrary.org/obo/GO_0002500 proteolysis within lysosome associated with antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002496 proteolysis associated with antigen processing and presentation The hydrolysis of a peptide bond or bonds within a protein by lysosomal resident proteases contributing to antigen processing and presentation. http://purl.obolibrary.org/obo/GO_0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II http://purl.obolibrary.org/obo/GO_0019882 antigen processing and presentation The process in which an antigen-presenting cell expresses antigen (peptide or polysaccharide) on its cell surface in association with an MHC class II protein complex. http://purl.obolibrary.org/obo/GO_0002507 tolerance induction http://purl.obolibrary.org/obo/GO_0002376 immune system process A process that directly activates any of the steps required for tolerance, a physiologic state in which the immune system does not react destructively against the components of an organism that harbors it or against antigens that are introduced to it. http://purl.obolibrary.org/obo/GO_0002514 B cell tolerance induction http://purl.obolibrary.org/obo/GO_0002507 tolerance induction A process involving any mechanism for tolerance induction in B cells. http://purl.obolibrary.org/obo/GO_0002515 B cell anergy http://purl.obolibrary.org/obo/GO_0002514 B cell tolerance induction Any process contributing to anergy in B cells, a state of functional inactivation which is part of B cell tolerance induction. http://purl.obolibrary.org/obo/GO_0002516 B cell deletion http://purl.obolibrary.org/obo/GO_1902742 apoptotic process involved in development The apoptotic death of B cells which is part of B cell tolerance induction. http://purl.obolibrary.org/obo/GO_0002517 T cell tolerance induction http://purl.obolibrary.org/obo/GO_0002507 tolerance induction A process involving any mechanism for tolerance induction in T cells. http://purl.obolibrary.org/obo/GO_0002519 natural killer cell tolerance induction http://purl.obolibrary.org/obo/GO_0002507 tolerance induction Tolerance induction of natural killer cells. http://purl.obolibrary.org/obo/GO_0002520 immune system development http://purl.obolibrary.org/obo/GO_0048731 system development The process whose specific outcome is the progression of an organismal system whose objective is to provide calibrated responses by an organism to a potential internal or invasive threat, over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process. http://purl.obolibrary.org/obo/GO_0002521 leukocyte differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized hemopoietic precursor cell acquires the specialized features of a leukocyte. A leukocyte is an achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue. http://purl.obolibrary.org/obo/GO_0002522 leukocyte migration involved in immune response http://purl.obolibrary.org/obo/GO_0050900 leukocyte migration The movement of a leukocyte within or between different tissues and organs of the body as part of an immune response. http://purl.obolibrary.org/obo/GO_0002523 leukocyte migration involved in inflammatory response http://purl.obolibrary.org/obo/GO_0050900 leukocyte migration The movement of a leukocyte within or between different tissues and organs of the body contributing to an inflammatory response. http://purl.obolibrary.org/obo/GO_0002526 acute inflammatory response http://purl.obolibrary.org/obo/GO_0006954 inflammatory response Inflammation which comprises a rapid, short-lived, relatively uniform response to acute injury or antigenic challenge and is characterized by accumulations of fluid, plasma proteins, and granulocytic leukocytes. An acute inflammatory response occurs within a matter of minutes or hours, and either resolves within a few days or becomes a chronic inflammatory response. http://purl.obolibrary.org/obo/GO_0002528 regulation of vascular permeability involved in acute inflammatory response http://purl.obolibrary.org/obo/GO_0043114 regulation of vascular permeability Any process that modulates the extent to which blood vessels can be pervaded by fluid contributing to an acute inflammatory response. http://purl.obolibrary.org/obo/GO_0002532 production of molecular mediator involved in inflammatory response http://purl.obolibrary.org/obo/GO_0032501 multicellular organismal process The synthesis or release of any molecular mediator of the inflammatory response following an inflammatory stimulus, resulting in an increase in its intracellular or extracellular levels. http://purl.obolibrary.org/obo/GO_0002534 cytokine production involved in inflammatory response http://purl.obolibrary.org/obo/GO_0002532 production of molecular mediator involved in inflammatory response The synthesis or release of a cytokine following a inflammatory stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels. http://purl.obolibrary.org/obo/GO_0002536 respiratory burst involved in inflammatory response http://purl.obolibrary.org/obo/GO_0002679 respiratory burst involved in defense response A phase of elevated metabolic activity, during which oxygen consumption increases following a stimulus as part of an inflammatory response; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals, resulting in an increase in their intracellular or extracellular levels. http://purl.obolibrary.org/obo/GO_0002537 nitric oxide production involved in inflammatory response http://purl.obolibrary.org/obo/GO_0002532 production of molecular mediator involved in inflammatory response The synthesis or release of nitric oxide following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels. http://purl.obolibrary.org/obo/GO_0002538 arachidonate metabolite production involved in inflammatory response http://purl.obolibrary.org/obo/GO_0002532 production of molecular mediator involved in inflammatory response The synthesis or release of products of arachidonic acid metabolism following a stimulus as part of an inflammatory response, resulting in an increase in their intracellular or extracellular levels. http://purl.obolibrary.org/obo/GO_0002539 prostaglandin production involved in inflammatory response http://purl.obolibrary.org/obo/GO_0002538 arachidonate metabolite production involved in inflammatory response The synthesis or release of any prostaglandin following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels. http://purl.obolibrary.org/obo/GO_0002540 leukotriene production involved in inflammatory response http://purl.obolibrary.org/obo/GO_0002538 arachidonate metabolite production involved in inflammatory response The synthesis or release of any leukotriene following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels. http://purl.obolibrary.org/obo/GO_0002544 chronic inflammatory response http://purl.obolibrary.org/obo/GO_0006954 inflammatory response Inflammation of prolonged duration (weeks or months) in which active inflammation, tissue destruction, and attempts at repair are proceeding simultaneously. Although it may follow acute inflammation, chronic inflammation frequently begins insidiously, as a low-grade, smoldering, often asymptomatic response. http://purl.obolibrary.org/obo/GO_0002548 monocyte chemotaxis http://purl.obolibrary.org/obo/GO_0097529 myeloid leukocyte migration The movement of a monocyte in response to an external stimulus. http://purl.obolibrary.org/obo/GO_0002551 mast cell chemotaxis http://purl.obolibrary.org/obo/GO_0097531 mast cell migration The movement of a mast cell in response to an external stimulus. http://purl.obolibrary.org/obo/GO_0002552 serotonin secretion by mast cell http://purl.obolibrary.org/obo/GO_0140029 exocytic process The regulated release of serotonin by a mast cell or group of mast cells. http://purl.obolibrary.org/obo/GO_0002553 histamine secretion by mast cell http://purl.obolibrary.org/obo/GO_0140029 exocytic process The regulated release of histamine by a mast cell or group of mast cells. http://purl.obolibrary.org/obo/GO_0002554 serotonin secretion by platelet http://purl.obolibrary.org/obo/GO_0140029 exocytic process The regulated release of serotonin by a platelet or group of platelets. http://purl.obolibrary.org/obo/GO_0002555 histamine secretion by platelet http://purl.obolibrary.org/obo/GO_0140029 exocytic process The regulated release of histamine by a platelet or group of platelets. http://purl.obolibrary.org/obo/GO_0002556 serotonin secretion by basophil http://purl.obolibrary.org/obo/GO_0140029 exocytic process The regulated release of serotonin by a basophil or group of basophils. http://purl.obolibrary.org/obo/GO_0002557 histamine secretion by basophil http://purl.obolibrary.org/obo/GO_0140029 exocytic process The regulated release of histamine by a basophil or group of basophils. http://purl.obolibrary.org/obo/GO_0002560 basophil mediated immunity http://purl.obolibrary.org/obo/GO_0002444 myeloid leukocyte mediated immunity Any process involved in the carrying out of an immune response by a basophil. http://purl.obolibrary.org/obo/GO_0002561 basophil degranulation http://purl.obolibrary.org/obo/GO_0043299 leukocyte degranulation The regulated exocytosis of secretory granules containing preformed mediators such as histamine, serotonin, and neutral proteases by a basophil. http://purl.obolibrary.org/obo/GO_0002562 somatic diversification of immune receptors via germline recombination within a single locus http://purl.obolibrary.org/obo/GO_0016444 somatic cell DNA recombination The process in which immune receptor genes are diversified through recombination of the germline genetic elements within a single genetic locus. http://purl.obolibrary.org/obo/GO_0002566 somatic diversification of immune receptors via somatic mutation http://purl.obolibrary.org/obo/GO_0002200 somatic diversification of immune receptors The process in which immune receptor genes are diversified through somatic mutation. http://purl.obolibrary.org/obo/GO_0002572 pro-T cell differentiation http://purl.obolibrary.org/obo/GO_0002320 lymphoid progenitor cell differentiation The process in which a precursor cell type acquires the specialized features of a pro-T cell. Pro-T cells are the earliest stage of the T cell lineage but are not fully committed. http://purl.obolibrary.org/obo/GO_0002573 myeloid leukocyte differentiation http://purl.obolibrary.org/obo/GO_0030099 myeloid cell differentiation The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte lineage. http://purl.obolibrary.org/obo/GO_0002574 thrombocyte differentiation http://purl.obolibrary.org/obo/GO_0030099 myeloid cell differentiation The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a thrombocyte, a nucleated cell found in all vertebrates but mammals involved in hemostasis. http://purl.obolibrary.org/obo/GO_0002575 basophil chemotaxis http://purl.obolibrary.org/obo/GO_0071621 granulocyte chemotaxis The movement of a basophil in response to an external stimulus. http://purl.obolibrary.org/obo/GO_0002576 platelet degranulation http://purl.obolibrary.org/obo/GO_0045055 regulated exocytosis The regulated exocytosis of secretory granules containing preformed mediators such as histamine and serotonin by a platelet. http://purl.obolibrary.org/obo/GO_0002577 regulation of antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002682 regulation of immune system process Any process that modulates the frequency, rate, or extent of antigen processing and presentation. http://purl.obolibrary.org/obo/GO_0002578 negative regulation of antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002683 negative regulation of immune system process Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation. http://purl.obolibrary.org/obo/GO_0002579 positive regulation of antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002684 positive regulation of immune system process Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation. http://purl.obolibrary.org/obo/GO_0002580 regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II http://purl.obolibrary.org/obo/GO_0002577 regulation of antigen processing and presentation Any process that modulates the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II. http://purl.obolibrary.org/obo/GO_0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II http://purl.obolibrary.org/obo/GO_0002580 regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II. http://purl.obolibrary.org/obo/GO_0002582 positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II http://purl.obolibrary.org/obo/GO_0002580 regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II. http://purl.obolibrary.org/obo/GO_0002583 regulation of antigen processing and presentation of peptide antigen http://purl.obolibrary.org/obo/GO_0002577 regulation of antigen processing and presentation Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen. http://purl.obolibrary.org/obo/GO_0002584 negative regulation of antigen processing and presentation of peptide antigen http://purl.obolibrary.org/obo/GO_0002583 regulation of antigen processing and presentation of peptide antigen Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of peptide antigen. http://purl.obolibrary.org/obo/GO_0002585 positive regulation of antigen processing and presentation of peptide antigen http://purl.obolibrary.org/obo/GO_0002583 regulation of antigen processing and presentation of peptide antigen Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of peptide antigen. http://purl.obolibrary.org/obo/GO_0002586 regulation of antigen processing and presentation of peptide antigen via MHC class II http://purl.obolibrary.org/obo/GO_0002583 regulation of antigen processing and presentation of peptide antigen Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class II. http://purl.obolibrary.org/obo/GO_0002587 negative regulation of antigen processing and presentation of peptide antigen via MHC class II http://purl.obolibrary.org/obo/GO_0002586 regulation of antigen processing and presentation of peptide antigen via MHC class II Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class II. http://purl.obolibrary.org/obo/GO_0002588 positive regulation of antigen processing and presentation of peptide antigen via MHC class II http://purl.obolibrary.org/obo/GO_0002586 regulation of antigen processing and presentation of peptide antigen via MHC class II Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class II. http://purl.obolibrary.org/obo/GO_0002589 regulation of antigen processing and presentation of peptide antigen via MHC class I http://purl.obolibrary.org/obo/GO_0002583 regulation of antigen processing and presentation of peptide antigen Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class I. http://purl.obolibrary.org/obo/GO_0002590 negative regulation of antigen processing and presentation of peptide antigen via MHC class I http://purl.obolibrary.org/obo/GO_0002589 regulation of antigen processing and presentation of peptide antigen via MHC class I Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class I. http://purl.obolibrary.org/obo/GO_0002591 positive regulation of antigen processing and presentation of peptide antigen via MHC class I http://purl.obolibrary.org/obo/GO_0002589 regulation of antigen processing and presentation of peptide antigen via MHC class I Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class I. http://purl.obolibrary.org/obo/GO_0002604 regulation of dendritic cell antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002577 regulation of antigen processing and presentation Any process that modulates the frequency, rate, or extent of dendritic cell antigen processing and presentation. http://purl.obolibrary.org/obo/GO_0002605 negative regulation of dendritic cell antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002604 regulation of dendritic cell antigen processing and presentation Any process that stops, prevents, or reduces the frequency, rate, or extent of dendritic cell antigen processing and presentation. http://purl.obolibrary.org/obo/GO_0002606 positive regulation of dendritic cell antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002604 regulation of dendritic cell antigen processing and presentation Any process that activates or increases the frequency, rate, or extent of dendritic cell antigen processing and presentation. http://purl.obolibrary.org/obo/GO_0002607 regulation of myeloid dendritic cell antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002604 regulation of dendritic cell antigen processing and presentation Any process that modulates the frequency, rate, or extent of myeloid dendritic cell antigen processing and presentation. http://purl.obolibrary.org/obo/GO_0002608 negative regulation of myeloid dendritic cell antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002607 regulation of myeloid dendritic cell antigen processing and presentation Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid dendritic cell antigen processing and presentation. http://purl.obolibrary.org/obo/GO_0002609 positive regulation of myeloid dendritic cell antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002607 regulation of myeloid dendritic cell antigen processing and presentation Any process that activates or increases the frequency, rate, or extent of myeloid dendritic cell antigen processing and presentation. http://purl.obolibrary.org/obo/GO_0002610 regulation of plasmacytoid dendritic cell antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002604 regulation of dendritic cell antigen processing and presentation Any process that modulates the frequency, rate, or extent of plasmacytoid dendritic cell antigen processing and presentation. http://purl.obolibrary.org/obo/GO_0002611 negative regulation of plasmacytoid dendritic cell antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002610 regulation of plasmacytoid dendritic cell antigen processing and presentation Any process that stops, prevents, or reduces the frequency, rate, or extent of plasmacytoid dendritic cell antigen processing and presentation. http://purl.obolibrary.org/obo/GO_0002612 positive regulation of plasmacytoid dendritic cell antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002610 regulation of plasmacytoid dendritic cell antigen processing and presentation Any process that activates or increases the frequency, rate, or extent of plasmacytoid dendritic cell antigen processing and presentation. http://purl.obolibrary.org/obo/GO_0002613 regulation of monocyte antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002577 regulation of antigen processing and presentation Any process that modulates the frequency, rate, or extent of monocyte antigen processing and presentation. http://purl.obolibrary.org/obo/GO_0002614 negative regulation of monocyte antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002613 regulation of monocyte antigen processing and presentation Any process that stops, prevents, or reduces the frequency, rate, or extent of monocyte antigen processing and presentation. http://purl.obolibrary.org/obo/GO_0002615 positive regulation of monocyte antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002613 regulation of monocyte antigen processing and presentation Any process that activates or increases the frequency, rate, or extent of monocyte antigen processing and presentation. http://purl.obolibrary.org/obo/GO_0002616 regulation of macrophage antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002577 regulation of antigen processing and presentation Any process that modulates the frequency, rate, or extent of macrophage antigen processing and presentation. http://purl.obolibrary.org/obo/GO_0002617 negative regulation of macrophage antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002616 regulation of macrophage antigen processing and presentation Any process that stops, prevents, or reduces the frequency, rate, or extent of macrophage antigen processing and presentation. http://purl.obolibrary.org/obo/GO_0002618 positive regulation of macrophage antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002616 regulation of macrophage antigen processing and presentation Any process that activates or increases the frequency, rate, or extent of macrophage antigen processing and presentation. http://purl.obolibrary.org/obo/GO_0002622 regulation of B cell antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002712 regulation of B cell mediated immunity Any process that modulates the frequency, rate, or extent of B cell antigen processing and presentation. http://purl.obolibrary.org/obo/GO_0002623 negative regulation of B cell antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002713 negative regulation of B cell mediated immunity Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell antigen processing and presentation. http://purl.obolibrary.org/obo/GO_0002624 positive regulation of B cell antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002622 regulation of B cell antigen processing and presentation Any process that activates or increases the frequency, rate, or extent of B cell antigen processing and presentation. http://purl.obolibrary.org/obo/GO_0002625 regulation of T cell antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002709 regulation of T cell mediated immunity Any process that modulates the frequency, rate, or extent of T cell antigen processing and presentation. http://purl.obolibrary.org/obo/GO_0002626 negative regulation of T cell antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002710 negative regulation of T cell mediated immunity Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell antigen processing and presentation. http://purl.obolibrary.org/obo/GO_0002627 positive regulation of T cell antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002711 positive regulation of T cell mediated immunity Any process that activates or increases the frequency, rate, or extent of T cell antigen processing and presentation. http://purl.obolibrary.org/obo/GO_0002628 regulation of proteolysis associated with antigen processing and presentation http://purl.obolibrary.org/obo/GO_0030162 regulation of proteolysis Any process that modulates the frequency, rate, or extent of proteolysis associated with antigen processing and presentation. http://purl.obolibrary.org/obo/GO_0002629 negative regulation of proteolysis associated with antigen processing and presentation http://purl.obolibrary.org/obo/GO_0045861 negative regulation of proteolysis Any process that stops, prevents, or reduces the frequency, rate, or extent of proteolysis associated with antigen processing and presentation. http://purl.obolibrary.org/obo/GO_0002630 positive regulation of proteolysis associated with antigen processing and presentation http://purl.obolibrary.org/obo/GO_0045862 positive regulation of proteolysis Any process that activates or increases the frequency, rate, or extent of proteolysis associated with antigen processing and presentation. http://purl.obolibrary.org/obo/GO_0002631 regulation of granuloma formation http://purl.obolibrary.org/obo/GO_0002697 regulation of immune effector process Any process that modulates the frequency, rate, or extent of granuloma formation. http://purl.obolibrary.org/obo/GO_0002632 negative regulation of granuloma formation http://purl.obolibrary.org/obo/GO_0002698 negative regulation of immune effector process Any process that stops, prevents, or reduces the frequency, rate, or extent of granuloma formation. http://purl.obolibrary.org/obo/GO_0002633 positive regulation of granuloma formation http://purl.obolibrary.org/obo/GO_0002699 positive regulation of immune effector process Any process that activates or increases the frequency, rate, or extent of granuloma formation. http://purl.obolibrary.org/obo/GO_0002634 regulation of germinal center formation http://purl.obolibrary.org/obo/GO_0022603 regulation of anatomical structure morphogenesis Any process that modulates the frequency, rate, or extent of germinal center formation. http://purl.obolibrary.org/obo/GO_0002635 negative regulation of germinal center formation http://purl.obolibrary.org/obo/GO_0051093 negative regulation of developmental process Any process that stops, prevents, or reduces the frequency, rate, or extent of germinal center formation. http://purl.obolibrary.org/obo/GO_0002636 positive regulation of germinal center formation http://purl.obolibrary.org/obo/GO_0051094 positive regulation of developmental process Any process that activates or increases the frequency, rate, or extent of germinal center formation. http://purl.obolibrary.org/obo/GO_0002637 regulation of immunoglobulin production http://purl.obolibrary.org/obo/GO_0002700 regulation of production of molecular mediator of immune response Any process that modulates the frequency, rate, or extent of immunoglobulin production. http://purl.obolibrary.org/obo/GO_0002638 negative regulation of immunoglobulin production http://purl.obolibrary.org/obo/GO_0002701 negative regulation of production of molecular mediator of immune response Any process that stops, prevents, or reduces the frequency, rate, or extent of immunoglobulin production. http://purl.obolibrary.org/obo/GO_0002639 positive regulation of immunoglobulin production http://purl.obolibrary.org/obo/GO_0002702 positive regulation of production of molecular mediator of immune response Any process that activates or increases the frequency, rate, or extent of immunoglobulin production. http://purl.obolibrary.org/obo/GO_0002643 regulation of tolerance induction http://purl.obolibrary.org/obo/GO_0002682 regulation of immune system process Any process that modulates the frequency, rate, or extent of tolerance induction. http://purl.obolibrary.org/obo/GO_0002644 negative regulation of tolerance induction http://purl.obolibrary.org/obo/GO_0051241 negative regulation of multicellular organismal process Any process that stops, prevents, or reduces the frequency, rate, or extent of tolerance induction. http://purl.obolibrary.org/obo/GO_0002645 positive regulation of tolerance induction http://purl.obolibrary.org/obo/GO_0051240 positive regulation of multicellular organismal process Any process that activates or increases the frequency, rate, or extent of tolerance induction. http://purl.obolibrary.org/obo/GO_0002652 regulation of tolerance induction dependent upon immune response http://purl.obolibrary.org/obo/GO_0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains Any process that modulates the frequency, rate, or extent of tolerance induction dependent upon immune response. http://purl.obolibrary.org/obo/GO_0002653 negative regulation of tolerance induction dependent upon immune response http://purl.obolibrary.org/obo/GO_0002823 negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains Any process that stops, prevents, or reduces the frequency, rate, or extent of tolerance induction dependent upon immune response. http://purl.obolibrary.org/obo/GO_0002654 positive regulation of tolerance induction dependent upon immune response http://purl.obolibrary.org/obo/GO_0002824 positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains Any process that activates or increases the frequency, rate, or extent of tolerance induction dependent upon immune response. http://purl.obolibrary.org/obo/GO_0002655 regulation of tolerance induction to nonself antigen http://purl.obolibrary.org/obo/GO_0002652 regulation of tolerance induction dependent upon immune response Any process that modulates the frequency, rate, or extent of tolerance induction to nonself antigen. http://purl.obolibrary.org/obo/GO_0002656 negative regulation of tolerance induction to nonself antigen http://purl.obolibrary.org/obo/GO_0002655 regulation of tolerance induction to nonself antigen Any process that stops, prevents, or reduces the frequency, rate, or extent of tolerance induction to nonself antigen. http://purl.obolibrary.org/obo/GO_0002657 positive regulation of tolerance induction to nonself antigen http://purl.obolibrary.org/obo/GO_0002655 regulation of tolerance induction to nonself antigen Any process that activates or increases the frequency, rate, or extent of tolerance induction to nonself antigen. http://purl.obolibrary.org/obo/GO_0002658 regulation of peripheral tolerance induction http://purl.obolibrary.org/obo/GO_0002652 regulation of tolerance induction dependent upon immune response Any process that modulates the frequency, rate, or extent of peripheral tolerance induction. http://purl.obolibrary.org/obo/GO_0002659 negative regulation of peripheral tolerance induction http://purl.obolibrary.org/obo/GO_0002658 regulation of peripheral tolerance induction Any process that stops, prevents, or reduces the frequency, rate, or extent of peripheral tolerance induction. http://purl.obolibrary.org/obo/GO_0002660 positive regulation of peripheral tolerance induction http://purl.obolibrary.org/obo/GO_0002658 regulation of peripheral tolerance induction Any process that activates or increases the frequency, rate, or extent of peripheral tolerance induction. http://purl.obolibrary.org/obo/GO_0002661 regulation of B cell tolerance induction http://purl.obolibrary.org/obo/GO_0002643 regulation of tolerance induction Any process that modulates the frequency, rate, or extent of B cell tolerance induction. http://purl.obolibrary.org/obo/GO_0002662 negative regulation of B cell tolerance induction http://purl.obolibrary.org/obo/GO_0002661 regulation of B cell tolerance induction Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell tolerance induction. http://purl.obolibrary.org/obo/GO_0002663 positive regulation of B cell tolerance induction http://purl.obolibrary.org/obo/GO_0002661 regulation of B cell tolerance induction Any process that activates or increases the frequency, rate, or extent of B cell tolerance induction. http://purl.obolibrary.org/obo/GO_0002664 regulation of T cell tolerance induction http://purl.obolibrary.org/obo/GO_0002643 regulation of tolerance induction Any process that modulates the frequency, rate, or extent of T cell tolerance induction. http://purl.obolibrary.org/obo/GO_0002665 negative regulation of T cell tolerance induction http://purl.obolibrary.org/obo/GO_0002664 regulation of T cell tolerance induction Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell tolerance induction. http://purl.obolibrary.org/obo/GO_0002666 positive regulation of T cell tolerance induction http://purl.obolibrary.org/obo/GO_0002664 regulation of T cell tolerance induction Any process that activates or increases the frequency, rate, or extent of T cell tolerance induction. http://purl.obolibrary.org/obo/GO_0002667 regulation of T cell anergy http://purl.obolibrary.org/obo/GO_0002911 regulation of lymphocyte anergy Any process that modulates the frequency, rate, or extent of T cell anergy. http://purl.obolibrary.org/obo/GO_0002668 negative regulation of T cell anergy http://purl.obolibrary.org/obo/GO_0002912 negative regulation of lymphocyte anergy Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell anergy. http://purl.obolibrary.org/obo/GO_0002669 positive regulation of T cell anergy http://purl.obolibrary.org/obo/GO_0002913 positive regulation of lymphocyte anergy Any process that activates or increases the frequency, rate, or extent of T cell anergy. http://purl.obolibrary.org/obo/GO_0002670 regulation of B cell anergy http://purl.obolibrary.org/obo/GO_0002911 regulation of lymphocyte anergy Any process that modulates the frequency, rate, or extent of B cell anergy. http://purl.obolibrary.org/obo/GO_0002671 negative regulation of B cell anergy http://purl.obolibrary.org/obo/GO_0002912 negative regulation of lymphocyte anergy Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell anergy. http://purl.obolibrary.org/obo/GO_0002672 positive regulation of B cell anergy http://purl.obolibrary.org/obo/GO_0002913 positive regulation of lymphocyte anergy Any process that activates or increases the frequency, rate, or extent of B cell anergy. http://purl.obolibrary.org/obo/GO_0002673 regulation of acute inflammatory response http://purl.obolibrary.org/obo/GO_0050727 regulation of inflammatory response Any process that modulates the frequency, rate, or extent of an acute inflammatory response. http://purl.obolibrary.org/obo/GO_0002674 negative regulation of acute inflammatory response http://purl.obolibrary.org/obo/GO_0050728 negative regulation of inflammatory response Any process that stops, prevents, or reduces the frequency, rate, or extent of an acute inflammatory response. http://purl.obolibrary.org/obo/GO_0002675 positive regulation of acute inflammatory response http://purl.obolibrary.org/obo/GO_0050729 positive regulation of inflammatory response Any process that activates or increases the frequency, rate, or extent of an acute inflammatory response. http://purl.obolibrary.org/obo/GO_0002676 regulation of chronic inflammatory response http://purl.obolibrary.org/obo/GO_0050727 regulation of inflammatory response Any process that modulates the frequency, rate, or extent of a chronic inflammatory response. http://purl.obolibrary.org/obo/GO_0002677 negative regulation of chronic inflammatory response http://purl.obolibrary.org/obo/GO_0050728 negative regulation of inflammatory response Any process that stops, prevents, or reduces the frequency, rate, or extent of a chronic inflammatory response. http://purl.obolibrary.org/obo/GO_0002678 positive regulation of chronic inflammatory response http://purl.obolibrary.org/obo/GO_0050729 positive regulation of inflammatory response Any process that activates or increases the frequency, rate, or extent of a chronic inflammatory response. http://purl.obolibrary.org/obo/GO_0002679 respiratory burst involved in defense response http://purl.obolibrary.org/obo/GO_0045730 respiratory burst A phase of elevated metabolic activity, during which oxygen consumption increases made as part of a defense response ; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals. http://purl.obolibrary.org/obo/GO_0002682 regulation of immune system process http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process Any process that modulates the frequency, rate, or extent of an immune system process. http://purl.obolibrary.org/obo/GO_0002683 negative regulation of immune system process http://purl.obolibrary.org/obo/GO_0048519 negative regulation of biological process Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune system process. http://purl.obolibrary.org/obo/GO_0002684 positive regulation of immune system process http://purl.obolibrary.org/obo/GO_0048518 positive regulation of biological process Any process that activates or increases the frequency, rate, or extent of an immune system process. http://purl.obolibrary.org/obo/GO_0002685 regulation of leukocyte migration http://purl.obolibrary.org/obo/GO_0030334 regulation of cell migration Any process that modulates the frequency, rate, or extent of leukocyte migration. http://purl.obolibrary.org/obo/GO_0002686 negative regulation of leukocyte migration http://purl.obolibrary.org/obo/GO_0030336 negative regulation of cell migration Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte migration. http://purl.obolibrary.org/obo/GO_0002687 positive regulation of leukocyte migration http://purl.obolibrary.org/obo/GO_0030335 positive regulation of cell migration Any process that activates or increases the frequency, rate, or extent of leukocyte migration. http://purl.obolibrary.org/obo/GO_0002688 regulation of leukocyte chemotaxis http://purl.obolibrary.org/obo/GO_0050920 regulation of chemotaxis Any process that modulates the frequency, rate, or extent of leukocyte chemotaxis. http://purl.obolibrary.org/obo/GO_0002689 negative regulation of leukocyte chemotaxis http://purl.obolibrary.org/obo/GO_0050922 negative regulation of chemotaxis Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte chemotaxis. http://purl.obolibrary.org/obo/GO_0002690 positive regulation of leukocyte chemotaxis http://purl.obolibrary.org/obo/GO_0050921 positive regulation of chemotaxis Any process that activates or increases the frequency, rate, or extent of leukocyte chemotaxis. http://purl.obolibrary.org/obo/GO_0002694 regulation of leukocyte activation http://purl.obolibrary.org/obo/GO_0050865 regulation of cell activation Any process that modulates the frequency, rate, or extent of leukocyte activation. http://purl.obolibrary.org/obo/GO_0002695 negative regulation of leukocyte activation http://purl.obolibrary.org/obo/GO_0050866 negative regulation of cell activation Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte activation. http://purl.obolibrary.org/obo/GO_0002696 positive regulation of leukocyte activation http://purl.obolibrary.org/obo/GO_0050867 positive regulation of cell activation Any process that activates or increases the frequency, rate, or extent of leukocyte activation. http://purl.obolibrary.org/obo/GO_0002697 regulation of immune effector process http://purl.obolibrary.org/obo/GO_0002682 regulation of immune system process Any process that modulates the frequency, rate, or extent of an immune effector process. http://purl.obolibrary.org/obo/GO_0002698 negative regulation of immune effector process http://purl.obolibrary.org/obo/GO_0002697 regulation of immune effector process Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune effector process. http://purl.obolibrary.org/obo/GO_0002699 positive regulation of immune effector process http://purl.obolibrary.org/obo/GO_0002697 regulation of immune effector process Any process that activates or increases the frequency, rate, or extent of an immune effector process. http://purl.obolibrary.org/obo/GO_0002700 regulation of production of molecular mediator of immune response http://purl.obolibrary.org/obo/GO_0010468 regulation of gene expression Any process that modulates the frequency, rate, or extent of the production of molecular mediator of immune response. http://purl.obolibrary.org/obo/GO_0002701 negative regulation of production of molecular mediator of immune response http://purl.obolibrary.org/obo/GO_0002700 regulation of production of molecular mediator of immune response Any process that stops, prevents, or reduces the frequency, rate, or extent of the production of molecular mediator of immune response. http://purl.obolibrary.org/obo/GO_0002702 positive regulation of production of molecular mediator of immune response http://purl.obolibrary.org/obo/GO_0010628 positive regulation of gene expression Any process that activates or increases the frequency, rate, or extent of the production of molecular mediator of immune response. http://purl.obolibrary.org/obo/GO_0002703 regulation of leukocyte mediated immunity http://purl.obolibrary.org/obo/GO_0002697 regulation of immune effector process Any process that modulates the frequency, rate, or extent of leukocyte mediated immunity. http://purl.obolibrary.org/obo/GO_0002704 negative regulation of leukocyte mediated immunity http://purl.obolibrary.org/obo/GO_0002703 regulation of leukocyte mediated immunity Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte mediated immunity. http://purl.obolibrary.org/obo/GO_0002705 positive regulation of leukocyte mediated immunity http://purl.obolibrary.org/obo/GO_0002703 regulation of leukocyte mediated immunity Any process that activates or increases the frequency, rate, or extent of leukocyte mediated immunity. http://purl.obolibrary.org/obo/GO_0002706 regulation of lymphocyte mediated immunity http://purl.obolibrary.org/obo/GO_0002703 regulation of leukocyte mediated immunity Any process that modulates the frequency, rate, or extent of lymphocyte mediated immunity. http://purl.obolibrary.org/obo/GO_0002707 negative regulation of lymphocyte mediated immunity http://purl.obolibrary.org/obo/GO_0002706 regulation of lymphocyte mediated immunity Any process that stops, prevents, or reduces the frequency, rate, or extent of lymphocyte mediated immunity. http://purl.obolibrary.org/obo/GO_0002708 positive regulation of lymphocyte mediated immunity http://purl.obolibrary.org/obo/GO_0002706 regulation of lymphocyte mediated immunity Any process that activates or increases the frequency, rate, or extent of lymphocyte mediated immunity. http://purl.obolibrary.org/obo/GO_0002709 regulation of T cell mediated immunity http://purl.obolibrary.org/obo/GO_0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains Any process that modulates the frequency, rate, or extent of T cell mediated immunity. http://purl.obolibrary.org/obo/GO_0002710 negative regulation of T cell mediated immunity http://purl.obolibrary.org/obo/GO_0002823 negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell mediated immunity. http://purl.obolibrary.org/obo/GO_0002711 positive regulation of T cell mediated immunity http://purl.obolibrary.org/obo/GO_0002824 positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains Any process that activates or increases the frequency, rate, or extent of T cell mediated immunity. http://purl.obolibrary.org/obo/GO_0002712 regulation of B cell mediated immunity http://purl.obolibrary.org/obo/GO_0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains Any process that modulates the frequency, rate, or extent of B cell mediated immunity. http://purl.obolibrary.org/obo/GO_0002713 negative regulation of B cell mediated immunity http://purl.obolibrary.org/obo/GO_0002823 negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell mediated immunity. http://purl.obolibrary.org/obo/GO_0002714 positive regulation of B cell mediated immunity http://purl.obolibrary.org/obo/GO_0002824 positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains Any process that activates or increases the frequency, rate, or extent of B cell mediated immunity. http://purl.obolibrary.org/obo/GO_0002715 regulation of natural killer cell mediated immunity http://purl.obolibrary.org/obo/GO_0045088 regulation of innate immune response Any process that modulates the frequency, rate, or extent of natural killer cell mediated immunity. http://purl.obolibrary.org/obo/GO_0002716 negative regulation of natural killer cell mediated immunity http://purl.obolibrary.org/obo/GO_0045824 negative regulation of innate immune response Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell mediated immunity. http://purl.obolibrary.org/obo/GO_0002717 positive regulation of natural killer cell mediated immunity http://purl.obolibrary.org/obo/GO_0045089 positive regulation of innate immune response Any process that activates or increases the frequency, rate, or extent of natural killer cell mediated immunity. http://purl.obolibrary.org/obo/GO_0002718 regulation of cytokine production involved in immune response http://purl.obolibrary.org/obo/GO_0002700 regulation of production of molecular mediator of immune response Any process that modulates the frequency, rate, or extent of cytokine production that contributes to an immune response. http://purl.obolibrary.org/obo/GO_0002719 negative regulation of cytokine production involved in immune response http://purl.obolibrary.org/obo/GO_0002718 regulation of cytokine production involved in immune response Any process that stops, prevents, or reduces the frequency, rate, or extent of cytokine production contributing to an immune response. http://purl.obolibrary.org/obo/GO_0002720 positive regulation of cytokine production involved in immune response http://purl.obolibrary.org/obo/GO_0002718 regulation of cytokine production involved in immune response Any process that activates or increases the frequency, rate, or extent of cytokine production that contributes to an immune response. http://purl.obolibrary.org/obo/GO_0002721 regulation of B cell cytokine production http://purl.obolibrary.org/obo/GO_0002718 regulation of cytokine production involved in immune response Any process that modulates the frequency, rate, or extent of B cell cytokine production. http://purl.obolibrary.org/obo/GO_0002722 negative regulation of B cell cytokine production http://purl.obolibrary.org/obo/GO_0002721 regulation of B cell cytokine production Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell cytokine production. http://purl.obolibrary.org/obo/GO_0002723 positive regulation of B cell cytokine production http://purl.obolibrary.org/obo/GO_0002721 regulation of B cell cytokine production Any process that activates or increases the frequency, rate, or extent of B cell cytokine production. http://purl.obolibrary.org/obo/GO_0002724 regulation of T cell cytokine production http://purl.obolibrary.org/obo/GO_0002718 regulation of cytokine production involved in immune response Any process that modulates the frequency, rate, or extent of T cell cytokine production. http://purl.obolibrary.org/obo/GO_0002725 negative regulation of T cell cytokine production http://purl.obolibrary.org/obo/GO_0002724 regulation of T cell cytokine production Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell cytokine production. http://purl.obolibrary.org/obo/GO_0002726 positive regulation of T cell cytokine production http://purl.obolibrary.org/obo/GO_0002724 regulation of T cell cytokine production Any process that activates or increases the frequency, rate, or extent of T cell cytokine production. http://purl.obolibrary.org/obo/GO_0002727 regulation of natural killer cell cytokine production http://purl.obolibrary.org/obo/GO_0002718 regulation of cytokine production involved in immune response Any process that modulates the frequency, rate, or extent of natural killer cell cytokine production. http://purl.obolibrary.org/obo/GO_0002728 negative regulation of natural killer cell cytokine production http://purl.obolibrary.org/obo/GO_0002727 regulation of natural killer cell cytokine production Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell cytokine production. http://purl.obolibrary.org/obo/GO_0002729 positive regulation of natural killer cell cytokine production http://purl.obolibrary.org/obo/GO_0002727 regulation of natural killer cell cytokine production Any process that activates or increases the frequency, rate, or extent of natural killer cell cytokine production. http://purl.obolibrary.org/obo/GO_0002730 regulation of dendritic cell cytokine production http://purl.obolibrary.org/obo/GO_0002718 regulation of cytokine production involved in immune response Any process that modulates the frequency, rate, or extent of dendritic cell cytokine production. http://purl.obolibrary.org/obo/GO_0002731 negative regulation of dendritic cell cytokine production http://purl.obolibrary.org/obo/GO_0002730 regulation of dendritic cell cytokine production Any process that stops, prevents, or reduces the frequency, rate, or extent of dendritic cell cytokine production. http://purl.obolibrary.org/obo/GO_0002732 positive regulation of dendritic cell cytokine production http://purl.obolibrary.org/obo/GO_0002730 regulation of dendritic cell cytokine production Any process that activates or increases the frequency, rate, or extent of dendritic cell cytokine production. http://purl.obolibrary.org/obo/GO_0002733 regulation of myeloid dendritic cell cytokine production http://purl.obolibrary.org/obo/GO_0002886 regulation of myeloid leukocyte mediated immunity Any process that modulates the frequency, rate, or extent of myeloid dendritic cell cytokine production. http://purl.obolibrary.org/obo/GO_0002734 negative regulation of myeloid dendritic cell cytokine production http://purl.obolibrary.org/obo/GO_0002887 negative regulation of myeloid leukocyte mediated immunity Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid dendritic cell cytokine production. http://purl.obolibrary.org/obo/GO_0002735 positive regulation of myeloid dendritic cell cytokine production http://purl.obolibrary.org/obo/GO_0061081 positive regulation of myeloid leukocyte cytokine production involved in immune response Any process that activates or increases the frequency, rate, or extent of myeloid dendritic cell cytokine production. http://purl.obolibrary.org/obo/GO_0002736 regulation of plasmacytoid dendritic cell cytokine production http://purl.obolibrary.org/obo/GO_0002730 regulation of dendritic cell cytokine production Any process that modulates the frequency, rate, or extent of plasmacytoid dendritic cell cytokine production. http://purl.obolibrary.org/obo/GO_0002737 negative regulation of plasmacytoid dendritic cell cytokine production http://purl.obolibrary.org/obo/GO_0002736 regulation of plasmacytoid dendritic cell cytokine production Any process that stops, prevents, or reduces the frequency, rate, or extent of plasmacytoid dendritic cell cytokine production. http://purl.obolibrary.org/obo/GO_0002738 positive regulation of plasmacytoid dendritic cell cytokine production http://purl.obolibrary.org/obo/GO_0002736 regulation of plasmacytoid dendritic cell cytokine production Any process that activates or increases the frequency, rate, or extent of plasmacytoid dendritic cell cytokine production. http://purl.obolibrary.org/obo/GO_0002759 regulation of antimicrobial humoral response http://purl.obolibrary.org/obo/GO_0031347 regulation of defense response Any process that modulates the frequency, rate, or extent of an antimicrobial humoral response. http://purl.obolibrary.org/obo/GO_0002760 positive regulation of antimicrobial humoral response http://purl.obolibrary.org/obo/GO_0032103 positive regulation of response to external stimulus Any process that activates or increases the frequency, rate, or extent of an antimicrobial humoral response. http://purl.obolibrary.org/obo/GO_0002761 regulation of myeloid leukocyte differentiation http://purl.obolibrary.org/obo/GO_1902105 regulation of leukocyte differentiation Any process that modulates the frequency, rate, or extent of myeloid leukocyte differentiation. http://purl.obolibrary.org/obo/GO_0002762 negative regulation of myeloid leukocyte differentiation http://purl.obolibrary.org/obo/GO_1902106 negative regulation of leukocyte differentiation Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid leukocyte differentiation. http://purl.obolibrary.org/obo/GO_0002763 positive regulation of myeloid leukocyte differentiation http://purl.obolibrary.org/obo/GO_1902107 positive regulation of leukocyte differentiation Any process that activates or increases the frequency, rate, or extent of myeloid leukocyte differentiation. http://purl.obolibrary.org/obo/GO_0002775 antimicrobial peptide production http://purl.obolibrary.org/obo/GO_0002440 production of molecular mediator of immune response The synthesis or release of an antimicrobial peptide during an immune response, resulting in an increase in intracellular or extracellular levels. Such peptides may have protective properties against bacteria, fungi, viruses, or protozoa. http://purl.obolibrary.org/obo/GO_0002776 antimicrobial peptide secretion http://purl.obolibrary.org/obo/GO_0002790 peptide secretion The regulated release of an antimicrobial peptide from a cell or a tissue. Such peptides may have protective properties against bacteria, fungi, viruses, or protozoa. http://purl.obolibrary.org/obo/GO_0002784 regulation of antimicrobial peptide production http://purl.obolibrary.org/obo/GO_0002759 regulation of antimicrobial humoral response Any process that modulates the frequency, rate, or extent of antimicrobial peptide production. http://purl.obolibrary.org/obo/GO_0002785 negative regulation of antimicrobial peptide production http://purl.obolibrary.org/obo/GO_0008348 negative regulation of antimicrobial humoral response Any process that stops, prevents, or reduces the frequency, rate, or extent of antimicrobial peptide production. http://purl.obolibrary.org/obo/GO_0002790 peptide secretion http://purl.obolibrary.org/obo/GO_0046903 secretion The controlled release of a peptide from a cell or a tissue. http://purl.obolibrary.org/obo/GO_0002791 regulation of peptide secretion http://purl.obolibrary.org/obo/GO_0090087 regulation of peptide transport Any process that modulates the frequency, rate, or extent of peptide secretion. http://purl.obolibrary.org/obo/GO_0002792 negative regulation of peptide secretion http://purl.obolibrary.org/obo/GO_0051048 negative regulation of secretion Any process that stops, prevents, or reduces the frequency, rate, or extent of peptide secretion. http://purl.obolibrary.org/obo/GO_0002793 positive regulation of peptide secretion http://purl.obolibrary.org/obo/GO_0051047 positive regulation of secretion Any process that activates or increases the frequency, rate, or extent of peptide secretion. http://purl.obolibrary.org/obo/GO_0002794 regulation of antimicrobial peptide secretion http://purl.obolibrary.org/obo/GO_0002791 regulation of peptide secretion Any process that modulates the frequency, rate, or extent of antimicrobial peptide secretion. http://purl.obolibrary.org/obo/GO_0002795 negative regulation of antimicrobial peptide secretion http://purl.obolibrary.org/obo/GO_0002794 regulation of antimicrobial peptide secretion Any process that stops, prevents, or reduces the frequency, rate, or extent of antimicrobial peptide secretion. http://purl.obolibrary.org/obo/GO_0002796 positive regulation of antimicrobial peptide secretion http://purl.obolibrary.org/obo/GO_0002794 regulation of antimicrobial peptide secretion Any process that activates or increases the frequency, rate, or extent of antimicrobial peptide secretion. http://purl.obolibrary.org/obo/GO_0002819 regulation of adaptive immune response http://purl.obolibrary.org/obo/GO_0050776 regulation of immune response Any process that modulates the frequency, rate, or extent of an adaptive immune response. http://purl.obolibrary.org/obo/GO_0002820 negative regulation of adaptive immune response http://purl.obolibrary.org/obo/GO_0050777 negative regulation of immune response Any process that stops, prevents, or reduces the frequency, rate, or extent of an adaptive immune response. http://purl.obolibrary.org/obo/GO_0002821 positive regulation of adaptive immune response http://purl.obolibrary.org/obo/GO_0050778 positive regulation of immune response Any process that activates or increases the frequency, rate, or extent of an adaptive immune response. http://purl.obolibrary.org/obo/GO_0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains http://purl.obolibrary.org/obo/GO_0002819 regulation of adaptive immune response Any process that modulates the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata. http://purl.obolibrary.org/obo/GO_0002823 negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains http://purl.obolibrary.org/obo/GO_0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains Any process that stops, prevents, or reduces the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata. http://purl.obolibrary.org/obo/GO_0002824 positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains http://purl.obolibrary.org/obo/GO_0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains Any process that activates or increases the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata. http://purl.obolibrary.org/obo/GO_0002825 regulation of T-helper 1 type immune response http://purl.obolibrary.org/obo/GO_0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains Any process that modulates the frequency, rate, or extent of a T-helper 1 type immune response. http://purl.obolibrary.org/obo/GO_0002826 negative regulation of T-helper 1 type immune response http://purl.obolibrary.org/obo/GO_0002825 regulation of T-helper 1 type immune response Any process that stops, prevents, or reduces the frequency, rate, or extent of a T-helper 1 type immune response. http://purl.obolibrary.org/obo/GO_0002827 positive regulation of T-helper 1 type immune response http://purl.obolibrary.org/obo/GO_0002825 regulation of T-helper 1 type immune response Any process that activates or increases the frequency, rate, or extent of a T-helper 1 type immune response. http://purl.obolibrary.org/obo/GO_0002828 regulation of type 2 immune response http://purl.obolibrary.org/obo/GO_0050776 regulation of immune response Any process that modulates the frequency, rate, or extent of a type 2 immune response. http://purl.obolibrary.org/obo/GO_0002829 negative regulation of type 2 immune response http://purl.obolibrary.org/obo/GO_0050777 negative regulation of immune response Any process that stops, prevents, or reduces the frequency, rate, or extent of a type 2 immune response. http://purl.obolibrary.org/obo/GO_0002830 positive regulation of type 2 immune response http://purl.obolibrary.org/obo/GO_0050778 positive regulation of immune response Any process that activates or increases the frequency, rate, or extent of a type 2 immune response. http://purl.obolibrary.org/obo/GO_0002831 regulation of response to biotic stimulus http://purl.obolibrary.org/obo/GO_0048583 regulation of response to stimulus Any process that modulates the frequency, rate, or extent of a response to biotic stimulus. http://purl.obolibrary.org/obo/GO_0002832 negative regulation of response to biotic stimulus http://purl.obolibrary.org/obo/GO_0048585 negative regulation of response to stimulus Any process that stops, prevents, or reduces the frequency, rate, or extent of a response to biotic stimulus. http://purl.obolibrary.org/obo/GO_0002833 positive regulation of response to biotic stimulus http://purl.obolibrary.org/obo/GO_0048584 positive regulation of response to stimulus Any process that activates or increases the frequency, rate, or extent of a response to biotic stimulus. http://purl.obolibrary.org/obo/GO_0002849 regulation of peripheral T cell tolerance induction http://purl.obolibrary.org/obo/GO_0002709 regulation of T cell mediated immunity Any process that modulates the frequency, rate, or extent of peripheral T cell tolerance induction. http://purl.obolibrary.org/obo/GO_0002850 negative regulation of peripheral T cell tolerance induction http://purl.obolibrary.org/obo/GO_0002849 regulation of peripheral T cell tolerance induction Any process that stops, prevents, or reduces the frequency, rate, or extent of peripheral T cell tolerance induction. http://purl.obolibrary.org/obo/GO_0002851 positive regulation of peripheral T cell tolerance induction http://purl.obolibrary.org/obo/GO_0002849 regulation of peripheral T cell tolerance induction Any process that activates or increases the frequency, rate, or extent of peripheral T cell tolerance induction. http://purl.obolibrary.org/obo/GO_0002867 regulation of B cell deletion http://purl.obolibrary.org/obo/GO_1904748 regulation of apoptotic process involved in development Any process that modulates the frequency, rate, or extent of B cell deletion. http://purl.obolibrary.org/obo/GO_0002868 negative regulation of B cell deletion http://purl.obolibrary.org/obo/GO_1904746 negative regulation of apoptotic process involved in development Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell deletion. http://purl.obolibrary.org/obo/GO_0002869 positive regulation of B cell deletion http://purl.obolibrary.org/obo/GO_1904747 positive regulation of apoptotic process involved in development Any process that activates or increases the frequency, rate, or extent of B cell deletion. http://purl.obolibrary.org/obo/GO_0002870 T cell anergy http://purl.obolibrary.org/obo/GO_0002517 T cell tolerance induction Any process contributing to anergy in T cells, a state of functional inactivation which is part of T cell tolerance induction. http://purl.obolibrary.org/obo/GO_0002871 regulation of natural killer cell tolerance induction http://purl.obolibrary.org/obo/GO_0002643 regulation of tolerance induction Any process that modulates the frequency, rate, or extent of natural killer cell tolerance induction. http://purl.obolibrary.org/obo/GO_0002872 negative regulation of natural killer cell tolerance induction http://purl.obolibrary.org/obo/GO_0002871 regulation of natural killer cell tolerance induction Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell tolerance induction. http://purl.obolibrary.org/obo/GO_0002873 positive regulation of natural killer cell tolerance induction http://purl.obolibrary.org/obo/GO_0002871 regulation of natural killer cell tolerance induction Any process that activates or increases the frequency, rate, or extent of natural killer cell tolerance induction. http://purl.obolibrary.org/obo/GO_0002886 regulation of myeloid leukocyte mediated immunity http://purl.obolibrary.org/obo/GO_0002703 regulation of leukocyte mediated immunity Any process that modulates the frequency, rate, or extent of myeloid leukocyte mediated immunity. http://purl.obolibrary.org/obo/GO_0002887 negative regulation of myeloid leukocyte mediated immunity http://purl.obolibrary.org/obo/GO_0002886 regulation of myeloid leukocyte mediated immunity Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid leukocyte mediated immunity. http://purl.obolibrary.org/obo/GO_0002888 positive regulation of myeloid leukocyte mediated immunity http://purl.obolibrary.org/obo/GO_0002886 regulation of myeloid leukocyte mediated immunity Any process that activates or increases the frequency, rate, or extent of myeloid leukocyte mediated immunity. http://purl.obolibrary.org/obo/GO_0002889 regulation of immunoglobulin mediated immune response http://purl.obolibrary.org/obo/GO_0002712 regulation of B cell mediated immunity Any process that modulates the frequency, rate, or extent of an immunoglobulin mediated immune response. http://purl.obolibrary.org/obo/GO_0002890 negative regulation of immunoglobulin mediated immune response http://purl.obolibrary.org/obo/GO_0002889 regulation of immunoglobulin mediated immune response Any process that stops, prevents, or reduces the frequency, rate, or extent of an immunoglobulin mediated immune response. http://purl.obolibrary.org/obo/GO_0002891 positive regulation of immunoglobulin mediated immune response http://purl.obolibrary.org/obo/GO_0002889 regulation of immunoglobulin mediated immune response Any process that activates or increases the frequency, rate, or extent of an immunoglobulin mediated immune response. http://purl.obolibrary.org/obo/GO_0002901 mature B cell apoptotic process http://purl.obolibrary.org/obo/GO_0001783 B cell apoptotic process Any apoptotic process in a B cell that is mature, having left the bone marrow. http://purl.obolibrary.org/obo/GO_0002902 regulation of B cell apoptotic process http://purl.obolibrary.org/obo/GO_0070228 regulation of lymphocyte apoptotic process Any process that modulates the frequency, rate, or extent of B cell apoptotic process. http://purl.obolibrary.org/obo/GO_0002903 negative regulation of B cell apoptotic process http://purl.obolibrary.org/obo/GO_0070229 negative regulation of lymphocyte apoptotic process Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell apoptotic process. http://purl.obolibrary.org/obo/GO_0002904 positive regulation of B cell apoptotic process http://purl.obolibrary.org/obo/GO_0070230 positive regulation of lymphocyte apoptotic process Any process that activates or increases the frequency, rate, or extent of B cell apoptotic process. http://purl.obolibrary.org/obo/GO_0002905 regulation of mature B cell apoptotic process http://purl.obolibrary.org/obo/GO_0002902 regulation of B cell apoptotic process Any process that modulates the frequency, rate, or extent of mature B cell apoptotic process. http://purl.obolibrary.org/obo/GO_0002906 negative regulation of mature B cell apoptotic process http://purl.obolibrary.org/obo/GO_0002905 regulation of mature B cell apoptotic process Any process that stops, prevents, or reduces the frequency, rate, or extent of mature B cell apoptotic process. http://purl.obolibrary.org/obo/GO_0002907 positive regulation of mature B cell apoptotic process http://purl.obolibrary.org/obo/GO_0002905 regulation of mature B cell apoptotic process Any process that activates or increases the frequency, rate, or extent of mature B cell apoptotic process. http://purl.obolibrary.org/obo/GO_0002911 regulation of lymphocyte anergy http://purl.obolibrary.org/obo/GO_0002643 regulation of tolerance induction Any process that modulates the frequency, rate, or extent of lymphocyte anergy. http://purl.obolibrary.org/obo/GO_0002912 negative regulation of lymphocyte anergy http://purl.obolibrary.org/obo/GO_0002911 regulation of lymphocyte anergy Any process that stops, prevents, or reduces the frequency, rate, or extent of lymphocyte anergy. http://purl.obolibrary.org/obo/GO_0002913 positive regulation of lymphocyte anergy http://purl.obolibrary.org/obo/GO_0002911 regulation of lymphocyte anergy Any process that activates or increases the frequency, rate, or extent of lymphocyte anergy. http://purl.obolibrary.org/obo/GO_0002920 regulation of humoral immune response http://purl.obolibrary.org/obo/GO_0050776 regulation of immune response Any process that modulates the frequency, rate, or extent of a humoral immune response. http://purl.obolibrary.org/obo/GO_0002921 negative regulation of humoral immune response http://purl.obolibrary.org/obo/GO_0050777 negative regulation of immune response Any process that stops, prevents, or reduces the frequency, rate, or extent of a humoral immune response. http://purl.obolibrary.org/obo/GO_0002922 positive regulation of humoral immune response http://purl.obolibrary.org/obo/GO_0050778 positive regulation of immune response Any process that activates or increases the frequency, rate, or extent of a humoral immune response. http://purl.obolibrary.org/obo/GO_0002930 trabecular meshwork development http://purl.obolibrary.org/obo/GO_0009888 tissue development The progression of the trabecular meshwork over time, from its formation to the mature structure. The trabecular meshwork is a fenestrated endothelial-like tissue situated at the intersection of the cornea and the iris. The trabecular meshwork provides drainage for the aqueous humor. http://purl.obolibrary.org/obo/GO_0002932 tendon sheath development http://purl.obolibrary.org/obo/GO_0061448 connective tissue development The process whose specific outcome is the progression of a tendon sheath over time, from its formation to the mature structure. A tendon sheath is a layer of membrane around a tendon. It permits the tendon to move. http://purl.obolibrary.org/obo/GO_0002934 desmosome organization http://purl.obolibrary.org/obo/GO_0045216 cell-cell junction organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a desmosome. A desmosome is a patch-like intercellular junction found in vertebrate tissues, consisting of parallel zones of two cell membranes, separated by an space of 25-35 nm, and having dense fibrillar plaques in the subjacent cytoplasm. http://purl.obolibrary.org/obo/GO_0002941 synoviocyte proliferation http://purl.obolibrary.org/obo/GO_0050673 epithelial cell proliferation The multiplication or reproduction of type B synoviocytes by cell division, resulting in the expansion of their population. A type B synoviocyte is a fibroblast-like cell found in synovial tissues. http://purl.obolibrary.org/obo/GO_0003002 regionalization http://purl.obolibrary.org/obo/GO_0007389 pattern specification process The pattern specification process that results in the subdivision of an axis or axes in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment. http://purl.obolibrary.org/obo/GO_0003006 developmental process involved in reproduction http://purl.obolibrary.org/obo/GO_0032502 developmental process A developmental process in which a progressive change in the state of some part of an organism, germline or somatic, specifically contributes to its ability to form offspring. http://purl.obolibrary.org/obo/GO_0003007 heart morphogenesis http://purl.obolibrary.org/obo/GO_0009887 animal organ morphogenesis The developmental process in which the heart is generated and organized. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. http://purl.obolibrary.org/obo/GO_0003008 system process http://purl.obolibrary.org/obo/GO_0032501 multicellular organismal process A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective. http://purl.obolibrary.org/obo/GO_0003009 skeletal muscle contraction http://purl.obolibrary.org/obo/GO_0006941 striated muscle contraction A process in which force is generated within skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the skeletal muscle, the muscle contraction takes advantage of an ordered sarcomeric structure and in most cases it is under voluntary control. http://purl.obolibrary.org/obo/GO_0003012 muscle system process http://purl.obolibrary.org/obo/GO_0003008 system process An organ system process carried out at the level of a muscle. Muscle tissue is composed of contractile cells or fibers. http://purl.obolibrary.org/obo/GO_0003013 circulatory system process http://purl.obolibrary.org/obo/GO_0003008 system process An organ system process carried out by any of the organs or tissues of the circulatory system. The circulatory system is an organ system that moves extracellular fluids to and from tissue within a multicellular organism. http://purl.obolibrary.org/obo/GO_0003014 renal system process http://purl.obolibrary.org/obo/GO_0003008 system process An organ system process carried out by any of the organs or tissues of the renal system. The renal system maintains fluid balance, and contributes to electrolyte balance, acid/base balance, and disposal of nitrogenous waste products. In humans, the renal system comprises a pair of kidneys, a pair of ureters, urinary bladder, urethra, sphincter muscle and associated blood vessels; in other species, the renal system may comprise related structures (e.g., nephrocytes and malpighian tubules in Drosophila). http://purl.obolibrary.org/obo/GO_0003015 heart process http://purl.obolibrary.org/obo/GO_0003013 circulatory system process A circulatory system process carried out by the heart. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. http://purl.obolibrary.org/obo/GO_0003016 respiratory system process http://purl.obolibrary.org/obo/GO_0003008 system process A process carried out by the organs or tissues of the respiratory system. The respiratory system is an organ system responsible for respiratory gaseous exchange. http://purl.obolibrary.org/obo/GO_0003018 vascular process in circulatory system http://purl.obolibrary.org/obo/GO_0003013 circulatory system process A circulatory process that occurs at the level of the vasculature. http://purl.obolibrary.org/obo/GO_0003032 detection of oxygen http://purl.obolibrary.org/obo/GO_0070482 response to oxygen levels The series of events in which an oxygen stimulus is received by a cell and converted into a molecular signal. http://purl.obolibrary.org/obo/GO_0003044 regulation of systemic arterial blood pressure mediated by a chemical signal http://purl.obolibrary.org/obo/GO_0003073 regulation of systemic arterial blood pressure The regulation of blood pressure mediated by biochemical signaling: hormonal, autocrine or paracrine. http://purl.obolibrary.org/obo/GO_0003071 renal system process involved in regulation of systemic arterial blood pressure http://purl.obolibrary.org/obo/GO_0003014 renal system process Renal process that modulates the force with which blood travels through the circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure. http://purl.obolibrary.org/obo/GO_0003073 regulation of systemic arterial blood pressure http://purl.obolibrary.org/obo/GO_0008217 regulation of blood pressure The process that modulates the force with which blood travels through the systemic arterial circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure. http://purl.obolibrary.org/obo/GO_0003081 regulation of systemic arterial blood pressure by renin-angiotensin http://purl.obolibrary.org/obo/GO_0001990 regulation of systemic arterial blood pressure by hormone The process in which renin-angiotensin modulates the force with which blood passes through the circulatory system. http://purl.obolibrary.org/obo/GO_0003091 renal water homeostasis http://purl.obolibrary.org/obo/GO_0050891 multicellular organismal-level water homeostasis Renal process involved in the maintenance of an internal steady state of water in the body. http://purl.obolibrary.org/obo/GO_0003093 regulation of glomerular filtration http://purl.obolibrary.org/obo/GO_0098801 regulation of renal system process Any process that modulates the frequency, rate or extent of glomerular filtration. Glomerular filtration is the process in which blood is filtered by the glomerulus into the renal tubule. http://purl.obolibrary.org/obo/GO_0003094 glomerular filtration http://purl.obolibrary.org/obo/GO_0097205 renal filtration The process in which plasma is filtered through the glomerular membrane which consists of capillary endothelial cells, the basement membrane, and epithelial cells. The glomerular filtrate is the same as plasma except it has no significant amount of protein. http://purl.obolibrary.org/obo/GO_0003096 renal sodium ion transport http://purl.obolibrary.org/obo/GO_0006814 sodium ion transport The directed movement of sodium ions (Na+) by the renal system. http://purl.obolibrary.org/obo/GO_0003097 renal water transport http://purl.obolibrary.org/obo/GO_0006833 water transport The directed movement of water (H2O) by the renal system. http://purl.obolibrary.org/obo/GO_0003104 positive regulation of glomerular filtration http://purl.obolibrary.org/obo/GO_0051240 positive regulation of multicellular organismal process Any process that activates or increases the frequency, rate or extent of glomerular filtration. Glomerular filtration is the process whereby blood is filtered by the glomerulus into the renal tubule. http://purl.obolibrary.org/obo/GO_0003105 negative regulation of glomerular filtration http://purl.obolibrary.org/obo/GO_0051241 negative regulation of multicellular organismal process Any process that stops, prevents, or reduces the frequency, rate or extent of glomerular filtration. Glomerular filtration is the process whereby blood is filtered by the glomerulus into the renal tubule. http://purl.obolibrary.org/obo/GO_0003131 mesodermal-endodermal cell signaling http://purl.obolibrary.org/obo/GO_0007267 cell-cell signaling Any process that mediates the transfer of information from mesodermal cells to endodermal cells. http://purl.obolibrary.org/obo/GO_0003133 endodermal-mesodermal cell signaling http://purl.obolibrary.org/obo/GO_0007267 cell-cell signaling Any process that mediates the transfer of information from endodermal cells to mesodermal cells. http://purl.obolibrary.org/obo/GO_0003142 cardiogenic plate morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structures of the cardiogenic plate are generated and organized. The cardiogenic plate is the first recognizable structure derived from the heart field. http://purl.obolibrary.org/obo/GO_0003143 embryonic heart tube morphogenesis http://purl.obolibrary.org/obo/GO_0060562 epithelial tube morphogenesis The process in which the anatomical structures of the embryonic heart tube are generated and organized. The embryonic heart tube is an epithelial tube that will give rise to the mature heart. http://purl.obolibrary.org/obo/GO_0003144 embryonic heart tube formation http://purl.obolibrary.org/obo/GO_0001838 embryonic epithelial tube formation The process that gives rise to the embryonic heart tube. This process pertains to the initial formation of a structure from unspecified parts. The embryonic heart tube is an epithelial tube that will give rise to the mature heart. http://purl.obolibrary.org/obo/GO_0003147 neural crest cell migration involved in heart formation http://purl.obolibrary.org/obo/GO_0060974 cell migration involved in heart formation The characteristic movement of a cell from the dorsal ridge of the neural tube towards the heart and that contributes to heart formation. http://purl.obolibrary.org/obo/GO_0003148 outflow tract septum morphogenesis http://purl.obolibrary.org/obo/GO_0060411 cardiac septum morphogenesis The process in which the anatomical structures of the outflow tract septum are generated and organized. The outflow tract septum is a partition in the outflow tract. http://purl.obolibrary.org/obo/GO_0003149 membranous septum morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the membranous septum is generated and organized. The membranous septum is the upper part of ventricular septum. http://purl.obolibrary.org/obo/GO_0003150 muscular septum morphogenesis http://purl.obolibrary.org/obo/GO_0060415 muscle tissue morphogenesis The process in which the muscular septum is generated and organized. The muscular septum is the lower part of the ventricular septum. http://purl.obolibrary.org/obo/GO_0003151 outflow tract morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structures of the outflow tract are generated and organized. The outflow tract is the portion of the heart through which blood flows into the arteries. http://purl.obolibrary.org/obo/GO_0003156 regulation of animal organ formation http://purl.obolibrary.org/obo/GO_2000027 regulation of animal organ morphogenesis Any process that modulates the rate, frequency or extent of animal organ formation. Organ formation is the process pertaining to the initial formation of an organ from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure, such as inductive events, and ends when the structural rudiment of the organ is recognizable, such as a condensation of mesenchymal cells into the organ rudiment. http://purl.obolibrary.org/obo/GO_0003157 endocardium development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the endocardium over time, from its formation to the mature structure. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers. http://purl.obolibrary.org/obo/GO_0003158 endothelium development http://purl.obolibrary.org/obo/GO_0060429 epithelium development The process whose specific outcome is the progression of an endothelium over time, from its formation to the mature structure. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells. http://purl.obolibrary.org/obo/GO_0003159 morphogenesis of an endothelium http://purl.obolibrary.org/obo/GO_0002009 morphogenesis of an epithelium The process in which the anatomical structure of an endothelium is generated and organized. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells. http://purl.obolibrary.org/obo/GO_0003160 endocardium morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structure of the endocardium is generated and organized. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers. http://purl.obolibrary.org/obo/GO_0003161 cardiac conduction system development http://purl.obolibrary.org/obo/GO_0048738 cardiac muscle tissue development The process whose specific outcome is the progression of the cardiac conduction system over time, from its formation to the mature structure. The cardiac conduction system consists of specialized cardiomyocytes that regulate the frequency of heart beat. http://purl.obolibrary.org/obo/GO_0003162 atrioventricular node development http://purl.obolibrary.org/obo/GO_0048738 cardiac muscle tissue development The process whose specific outcome is the progression of the atrioventricular (AV) node over time, from its formation to the mature structure. The AV node is part of the cardiac conduction system that controls the timing of ventricle contraction by receiving electrical signals from the sinoatrial (SA) node and relaying them to the His-Purkinje system. http://purl.obolibrary.org/obo/GO_0003163 sinoatrial node development http://purl.obolibrary.org/obo/GO_0003228 atrial cardiac muscle tissue development The process whose specific outcome is the progression of the sinoatrial (SA) node over time, from its formation to the mature structure. The SA node is part of the cardiac conduction system that controls the timing of heart muscle contraction. It relays electrical signals to the AV node. http://purl.obolibrary.org/obo/GO_0003164 His-Purkinje system development http://purl.obolibrary.org/obo/GO_0003229 ventricular cardiac muscle tissue development The process whose specific outcome is the progression of the His-Purkinje system over time, from its formation to the mature structure. The His-Purkinje system receives signals from the AV node and is composed of the fibers that regulate cardiac muscle contraction in the ventricles. http://purl.obolibrary.org/obo/GO_0003165 Purkinje myocyte development http://purl.obolibrary.org/obo/GO_0003229 ventricular cardiac muscle tissue development The process whose specific outcome is the progression of a Purkinje myocyte over time, from its formation to the mature structure. The Purkinje myocyte (also known as cardiac Purkinje fiber) is part of the cardiac conduction system that receives signals from the bundle of His and innervates the ventricular cardiac muscle. http://purl.obolibrary.org/obo/GO_0003166 bundle of His development http://purl.obolibrary.org/obo/GO_0003229 ventricular cardiac muscle tissue development The process whose specific outcome is the progression of the bundle of His over time, from its formation to the mature structure. The bundle of His is part of the His-Purkinje system that transmits signals from the AV node to the cardiac Purkinje fibers. http://purl.obolibrary.org/obo/GO_0003167 atrioventricular bundle cell differentiation http://purl.obolibrary.org/obo/GO_0060932 His-Purkinje system cell differentiation The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell of the atrioventricular bundle. These cells are specialized cardiomyocytes that transmit signals from the AV node to the cardiac Purkinje fibers. http://purl.obolibrary.org/obo/GO_0003168 Purkinje myocyte differentiation http://purl.obolibrary.org/obo/GO_0060932 His-Purkinje system cell differentiation The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a Purkinje myocyte (also known as cardiac Purkinje fiber cell). These cells are specialized cardiomyocytes that receive signals from the bundle of His and innervate the ventricular cardiac muscle. http://purl.obolibrary.org/obo/GO_0003169 coronary vein morphogenesis http://purl.obolibrary.org/obo/GO_0060977 coronary vasculature morphogenesis The process in which the anatomical structures of veins of the heart are generated and organized. http://purl.obolibrary.org/obo/GO_0003170 heart valve development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of a heart valve over time, from its formation to the mature structure. A heart valve is a structure that restricts the flow of blood to different regions of the heart and forms from an endocardial cushion. http://purl.obolibrary.org/obo/GO_0003179 heart valve morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the structure of a heart valve is generated and organized. http://purl.obolibrary.org/obo/GO_0003188 heart valve formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The developmental process pertaining to the initial formation of a heart valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. http://purl.obolibrary.org/obo/GO_0003197 endocardial cushion development http://purl.obolibrary.org/obo/GO_0060485 mesenchyme development The progression of a cardiac cushion over time, from its initial formation to the mature structure. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves. http://purl.obolibrary.org/obo/GO_0003203 endocardial cushion morphogenesis http://purl.obolibrary.org/obo/GO_0072132 mesenchyme morphogenesis The process in which the anatomical structure of the endocardial cushion is generated and organized. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves. http://purl.obolibrary.org/obo/GO_0003204 cardiac skeleton development http://purl.obolibrary.org/obo/GO_0061448 connective tissue development The progression of the cardiac skeleton over time, from its formation to the mature structure. The cardiac skeleton is a specialized extracellular matrix that separates the atria from the ventricles and provides physical support for the heart. http://purl.obolibrary.org/obo/GO_0003205 cardiac chamber development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of a cardiac chamber over time, from its formation to the mature structure. A cardiac chamber is an enclosed cavity within the heart. http://purl.obolibrary.org/obo/GO_0003206 cardiac chamber morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which a cardiac chamber is generated and organized. A cardiac chamber is an enclosed cavity within the heart. http://purl.obolibrary.org/obo/GO_0003207 cardiac chamber formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The developmental process pertaining to the initial formation of a cardiac chamber from unspecified parts. A cardiac chamber is an enclosed cavity within the heart. http://purl.obolibrary.org/obo/GO_0003208 cardiac ventricle morphogenesis http://purl.obolibrary.org/obo/GO_0003206 cardiac chamber morphogenesis The process in which the cardiac ventricle is generated and organized. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart. http://purl.obolibrary.org/obo/GO_0003209 cardiac atrium morphogenesis http://purl.obolibrary.org/obo/GO_0003206 cardiac chamber morphogenesis The process in which the cardiac atrium is generated and organized. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle. http://purl.obolibrary.org/obo/GO_0003210 cardiac atrium formation http://purl.obolibrary.org/obo/GO_0003207 cardiac chamber formation The developmental process pertaining to the initial formation of a cardiac atrium from unspecified parts. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle. http://purl.obolibrary.org/obo/GO_0003211 cardiac ventricle formation http://purl.obolibrary.org/obo/GO_0003207 cardiac chamber formation The developmental process pertaining to the initial formation of a cardiac ventricle from unspecified parts. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart. http://purl.obolibrary.org/obo/GO_0003212 cardiac left atrium morphogenesis http://purl.obolibrary.org/obo/GO_0003209 cardiac atrium morphogenesis The process in which the left cardiac atrium is generated and organized. http://purl.obolibrary.org/obo/GO_0003213 cardiac right atrium morphogenesis http://purl.obolibrary.org/obo/GO_0003209 cardiac atrium morphogenesis The process in which the right cardiac atrium is generated and organized. http://purl.obolibrary.org/obo/GO_0003214 cardiac left ventricle morphogenesis http://purl.obolibrary.org/obo/GO_0003208 cardiac ventricle morphogenesis The process in which the left cardiac ventricle is generated and organized. http://purl.obolibrary.org/obo/GO_0003215 cardiac right ventricle morphogenesis http://purl.obolibrary.org/obo/GO_0003208 cardiac ventricle morphogenesis The process in which the right cardiac ventricle is generated and organized. http://purl.obolibrary.org/obo/GO_0003216 cardiac left atrium formation http://purl.obolibrary.org/obo/GO_0003210 cardiac atrium formation The developmental process pertaining to the initial formation of a left cardiac atrium from unspecified parts. http://purl.obolibrary.org/obo/GO_0003217 cardiac right atrium formation http://purl.obolibrary.org/obo/GO_0003210 cardiac atrium formation The developmental process pertaining to the initial formation of a cardiac right atrium from unspecified parts. http://purl.obolibrary.org/obo/GO_0003218 cardiac left ventricle formation http://purl.obolibrary.org/obo/GO_0003211 cardiac ventricle formation The developmental process pertaining to the initial formation of a left cardiac ventricle from unspecified parts. http://purl.obolibrary.org/obo/GO_0003219 cardiac right ventricle formation http://purl.obolibrary.org/obo/GO_0003211 cardiac ventricle formation The developmental process pertaining to the initial formation of a right cardiac ventricle from unspecified parts. http://purl.obolibrary.org/obo/GO_0003220 left ventricular cardiac muscle tissue morphogenesis http://purl.obolibrary.org/obo/GO_0055010 ventricular cardiac muscle tissue morphogenesis The process in which the anatomical structures of left cardiac ventricle muscle are generated and organized. http://purl.obolibrary.org/obo/GO_0003221 right ventricular cardiac muscle tissue morphogenesis http://purl.obolibrary.org/obo/GO_0055010 ventricular cardiac muscle tissue morphogenesis The process in which the anatomical structures of the right cardiac ventricle muscle are generated and organized. http://purl.obolibrary.org/obo/GO_0003222 ventricular trabecula myocardium morphogenesis http://purl.obolibrary.org/obo/GO_0061384 heart trabecula morphogenesis The process in which the anatomical structures of the trabecular cardiac ventricle muscle are generated and organized. http://purl.obolibrary.org/obo/GO_0003225 left ventricular trabecular myocardium morphogenesis http://purl.obolibrary.org/obo/GO_0003222 ventricular trabecula myocardium morphogenesis The process in which the anatomical structures of cardiac left ventricular trabecular myocardium are generated and organized. http://purl.obolibrary.org/obo/GO_0003227 right ventricular trabecular myocardium morphogenesis http://purl.obolibrary.org/obo/GO_0003222 ventricular trabecula myocardium morphogenesis The process in which the anatomical structures of the right ventricular myocardium are generated and organized. http://purl.obolibrary.org/obo/GO_0003228 atrial cardiac muscle tissue development http://purl.obolibrary.org/obo/GO_0048738 cardiac muscle tissue development The process whose specific outcome is the progression of cardiac muscle of the atrium over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0003229 ventricular cardiac muscle tissue development http://purl.obolibrary.org/obo/GO_0048738 cardiac muscle tissue development The process whose specific outcome is the progression of ventricular cardiac muscle over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0003230 cardiac atrium development http://purl.obolibrary.org/obo/GO_0003205 cardiac chamber development The process whose specific outcome is the progression of a cardiac atrium over time, from its formation to the mature structure. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle. http://purl.obolibrary.org/obo/GO_0003231 cardiac ventricle development http://purl.obolibrary.org/obo/GO_0003205 cardiac chamber development The process whose specific outcome is the progression of a cardiac ventricle over time, from its formation to the mature structure. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart. http://purl.obolibrary.org/obo/GO_0003235 sinus venosus development http://purl.obolibrary.org/obo/GO_0003205 cardiac chamber development The progression of the sinus venosus over time, from its formation to the mature structure. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart. http://purl.obolibrary.org/obo/GO_0003236 sinus venosus morphogenesis http://purl.obolibrary.org/obo/GO_0003206 cardiac chamber morphogenesis The process in which the sinus venosus is generated and organized. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart. http://purl.obolibrary.org/obo/GO_0003237 sinus venosus formation http://purl.obolibrary.org/obo/GO_0003207 cardiac chamber formation The developmental process pertaining to the initial formation of the sinus venosus from unspecified parts. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart. http://purl.obolibrary.org/obo/GO_0003241 growth involved in heart morphogenesis http://purl.obolibrary.org/obo/GO_0060560 developmental growth involved in morphogenesis Developmental growth that contributes to the shaping of the heart. http://purl.obolibrary.org/obo/GO_0003245 cardiac muscle tissue growth involved in heart morphogenesis http://purl.obolibrary.org/obo/GO_0055017 cardiac muscle tissue growth The developmental growth of cardiac muscle tissue that contributes to the shaping of the heart. http://purl.obolibrary.org/obo/GO_0003248 heart capillary growth http://purl.obolibrary.org/obo/GO_0048589 developmental growth The increase in heart capillaries that accompanies physiological hypertrophy of cardiac muscle. http://purl.obolibrary.org/obo/GO_0003253 cardiac neural crest cell migration involved in outflow tract morphogenesis http://purl.obolibrary.org/obo/GO_0060973 cell migration involved in heart development The orderly movement of a neural crest cell from one site to another that will contribute to the morphogenesis of the outflow tract. http://purl.obolibrary.org/obo/GO_0003254 regulation of membrane depolarization http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that modulates the rate, frequency or extent of membrane depolarization. Membrane depolarization is the process in which membrane potential changes in the depolarizing direction from the resting potential, usually from negative to positive. http://purl.obolibrary.org/obo/GO_0003260 cardioblast migration http://purl.obolibrary.org/obo/GO_0060974 cell migration involved in heart formation The orderly movement of a cardiac progenitor cell to form the heart field. Cardiac progenitor cells are non-terminally differentiated, mesoderm-derived cells that are committed to differentiate into cells of the heart. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. http://purl.obolibrary.org/obo/GO_0003272 endocardial cushion formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The developmental process pertaining to the initial formation of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves. http://purl.obolibrary.org/obo/GO_0003273 cell migration involved in endocardial cushion formation http://purl.obolibrary.org/obo/GO_0060973 cell migration involved in heart development The orderly movement of a cell from one site to another that will contribute to the formation of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves. http://purl.obolibrary.org/obo/GO_0003274 endocardial cushion fusion http://purl.obolibrary.org/obo/GO_0098609 cell-cell adhesion The cell-cell adhesion process of mesenchymal cardiac cushion cells that contributes to the process of cushion shaping. http://purl.obolibrary.org/obo/GO_0003275 apoptotic process involved in outflow tract morphogenesis http://purl.obolibrary.org/obo/GO_0003278 apoptotic process involved in heart morphogenesis Any apoptotic process that contributes to the shaping of the outflow tract. The outflow tract is the portion of the heart through which blood flows into the arteries. http://purl.obolibrary.org/obo/GO_0003277 apoptotic process involved in endocardial cushion morphogenesis http://purl.obolibrary.org/obo/GO_0003278 apoptotic process involved in heart morphogenesis Any apoptotic process that contributes to the shaping of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves. http://purl.obolibrary.org/obo/GO_0003278 apoptotic process involved in heart morphogenesis http://purl.obolibrary.org/obo/GO_0060561 apoptotic process involved in morphogenesis Any apoptotic process that contributes to the shaping of the heart. http://purl.obolibrary.org/obo/GO_0003279 cardiac septum development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of a cardiac septum over time, from its initial formation to the mature structure. http://purl.obolibrary.org/obo/GO_0003281 ventricular septum development http://purl.obolibrary.org/obo/GO_0003279 cardiac septum development The progression of the ventricular septum over time from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0003283 atrial septum development http://purl.obolibrary.org/obo/GO_0003279 cardiac septum development The progression of the atrial septum over time, from its initial formation to the mature structure. http://purl.obolibrary.org/obo/GO_0003292 cardiac septum cell differentiation http://purl.obolibrary.org/obo/GO_0035051 cardiocyte differentiation The process in which an endocardial cushion cell becomes a cell of a cardiac septum. http://purl.obolibrary.org/obo/GO_0003293 heart valve cell differentiation http://purl.obolibrary.org/obo/GO_0035051 cardiocyte differentiation The process in which an endocardial cushion cell give rise to a cell that is part of a heart valve. http://purl.obolibrary.org/obo/GO_0003298 physiological muscle hypertrophy http://purl.obolibrary.org/obo/GO_0014896 muscle hypertrophy The enlargement or overgrowth of all or part of a muscle organ or tissue due to an increase in the size of its muscle cells. Physiological hypertrophy is a normal process during development. http://purl.obolibrary.org/obo/GO_0003300 cardiac muscle hypertrophy http://purl.obolibrary.org/obo/GO_0014897 striated muscle hypertrophy The enlargement or overgrowth of all or part of the heart muscle due to an increase in size of cardiac muscle cells without cell division. http://purl.obolibrary.org/obo/GO_0003301 physiological cardiac muscle hypertrophy http://purl.obolibrary.org/obo/GO_0003300 cardiac muscle hypertrophy The enlargement or overgrowth of all or part of the heart muscle due to an increase in size of cardiac muscle cells without cell division. This process contributes to the developmental growth of the heart. http://purl.obolibrary.org/obo/GO_0003309 type B pancreatic cell differentiation http://purl.obolibrary.org/obo/GO_0035883 enteroendocrine cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features of a type B pancreatic cell. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin. http://purl.obolibrary.org/obo/GO_0003310 pancreatic A cell differentiation http://purl.obolibrary.org/obo/GO_0035883 enteroendocrine cell differentiation The process in which relatively unspecialized cells acquire specialized structural and functional features of a pancreatic A cell. A pancreatic A cell is a cell in the pancreas that secretes glucagon. http://purl.obolibrary.org/obo/GO_0003311 pancreatic D cell differentiation http://purl.obolibrary.org/obo/GO_7770025 intestinal type D enteroendocrine cell differentiation The process in which relatively unspecialized cells acquire specialized structural and functional features that characterize a pancreatic delta cell. A delta cell is a cell of the pancreas that produces somatostatin. http://purl.obolibrary.org/obo/GO_0003312 pancreatic PP cell differentiation http://purl.obolibrary.org/obo/GO_0035883 enteroendocrine cell differentiation The process in which relatively unspecialized cells acquire specialized structural and functional features of a pancreatic polypeptide-producing cell. A pancreatic polypeptide-producing cell is a cell in the pancreas that produces pancreatic polypeptide. http://purl.obolibrary.org/obo/GO_0003313 heart rudiment development http://purl.obolibrary.org/obo/GO_0060429 epithelium development The progression of the heart rudiment over time, from its initial formation to the mature structure. The heart rudiment is a cone-like structure that is formed when myocardial progenitor cells of the heart field fuse at the midline. The heart rudiment is the first structure of the heart tube. http://purl.obolibrary.org/obo/GO_0003314 heart rudiment morphogenesis http://purl.obolibrary.org/obo/GO_0048598 embryonic morphogenesis The process in which the anatomical structures of the heart rudiment are generated and organized. http://purl.obolibrary.org/obo/GO_0003315 heart rudiment formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The developmental process pertaining to the initial formation of the heart rudiment. http://purl.obolibrary.org/obo/GO_0003322 pancreatic A cell development http://purl.obolibrary.org/obo/GO_0002064 epithelial cell development The process whose specific outcome is the progression of a pancreatic A cell over time, from its formation to the mature structure. A pancreatic A cell is a cell in the pancreas that secretes glucagon. http://purl.obolibrary.org/obo/GO_0003323 type B pancreatic cell development http://purl.obolibrary.org/obo/GO_0002064 epithelial cell development The process whose specific outcome is the progression of a type B pancreatic cell over time, from its formation to the mature structure. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin. http://purl.obolibrary.org/obo/GO_0003324 pancreatic D cell development http://purl.obolibrary.org/obo/GO_0048666 neuron development The process whose specific outcome is the progression of a pancreatic delta cell over time, from its formation to the mature structure. A delta cell is a cell of the pancreas that produces somatostatin. http://purl.obolibrary.org/obo/GO_0003325 pancreatic PP cell development http://purl.obolibrary.org/obo/GO_0002064 epithelial cell development The process whose specific outcome is the progression of a pancreatic PP cell over time, from its formation to the mature structure. A pancreatic polypeptide-producing cell is a cell in the pancreas that produces pancreatic polypeptide. http://purl.obolibrary.org/obo/GO_0003330 regulation of extracellular matrix constituent secretion http://purl.obolibrary.org/obo/GO_1903530 regulation of secretion by cell Any process that modulates the rate, frequency, or extent of the controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell or a group of cells. http://purl.obolibrary.org/obo/GO_0003331 positive regulation of extracellular matrix constituent secretion http://purl.obolibrary.org/obo/GO_1903532 positive regulation of secretion by cell Any process that increases the rate, frequency, or extent of the controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell or a group of cells. http://purl.obolibrary.org/obo/GO_0003332 negative regulation of extracellular matrix constituent secretion http://purl.obolibrary.org/obo/GO_1903531 negative regulation of secretion by cell Any process that decreases the rate, frequency, or extent the controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell or a group of cells. http://purl.obolibrary.org/obo/GO_0003333 amino acid transmembrane transport http://purl.obolibrary.org/obo/GO_0006865 amino acid transport The process in which an amino acid is transported across a membrane. http://purl.obolibrary.org/obo/GO_0003334 keratinocyte development http://purl.obolibrary.org/obo/GO_0002064 epithelial cell development The process whose specific outcome is the progression of a keratinocyte over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0003335 corneocyte development http://purl.obolibrary.org/obo/GO_0048468 cell development The process whose specific outcome is the progression of the corneocyte over time, from its formation to the mature structure. A corneocyte is the last stage of development of a keratinocyte where the keratinocyte flattens, loses its nucleus and eventually delaminates from the epidermis. http://purl.obolibrary.org/obo/GO_0003337 mesenchymal to epithelial transition involved in metanephros morphogenesis http://purl.obolibrary.org/obo/GO_0060231 mesenchymal to epithelial transition A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros. http://purl.obolibrary.org/obo/GO_0003338 metanephros morphogenesis http://purl.obolibrary.org/obo/GO_0060993 kidney morphogenesis The process in which the anatomical structures of the metanephros are generated and organized. http://purl.obolibrary.org/obo/GO_0003339 regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis http://purl.obolibrary.org/obo/GO_2000696 regulation of epithelial cell differentiation involved in kidney development Any process that modulates the rate, frequency or extent of the transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros. http://purl.obolibrary.org/obo/GO_0003340 negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis http://purl.obolibrary.org/obo/GO_2000697 negative regulation of epithelial cell differentiation involved in kidney development Any process that decreases the rate, frequency or extent of the transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros. http://purl.obolibrary.org/obo/GO_0003341 cilium movement http://purl.obolibrary.org/obo/GO_0007018 microtubule-based movement The directed, self-propelled movement of a cilium. http://purl.obolibrary.org/obo/GO_0003342 proepicardium development http://purl.obolibrary.org/obo/GO_0060485 mesenchyme development The progression of the proepicardium from its formation to the mature structure. The proepicardium is an outpouching of the septum transversum. http://purl.obolibrary.org/obo/GO_0003343 septum transversum development http://purl.obolibrary.org/obo/GO_0060485 mesenchyme development The progression of the septum transversum from its initial formation to the mature structure. The septum transversum is a portion of the trunk mesenchyme. http://purl.obolibrary.org/obo/GO_0003344 pericardium morphogenesis http://purl.obolibrary.org/obo/GO_0048598 embryonic morphogenesis The process in which the anatomical structure of the pericardium is generated and organized. http://purl.obolibrary.org/obo/GO_0003348 cardiac endothelial cell differentiation http://purl.obolibrary.org/obo/GO_0045446 endothelial cell differentiation The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cardiac endothelial cell. http://purl.obolibrary.org/obo/GO_0003352 regulation of cilium movement http://purl.obolibrary.org/obo/GO_0060632 regulation of microtubule-based movement Any process that modulates the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium. http://purl.obolibrary.org/obo/GO_0003353 positive regulation of cilium movement http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that increases the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium. http://purl.obolibrary.org/obo/GO_0003354 negative regulation of cilium movement http://purl.obolibrary.org/obo/GO_0003352 regulation of cilium movement Any process that decreases the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium. http://purl.obolibrary.org/obo/GO_0003357 noradrenergic neuron differentiation http://purl.obolibrary.org/obo/GO_0030182 neuron differentiation The process in which a relatively unspecialized cell acquires specialized features of an noradrenergic neuron, a neuron that secretes noradrenaline. http://purl.obolibrary.org/obo/GO_0003358 noradrenergic neuron development http://purl.obolibrary.org/obo/GO_0048666 neuron development The process whose specific outcome is the progression of a noradrenergic neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. http://purl.obolibrary.org/obo/GO_0003360 brainstem development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the brainstem from its formation to the mature structure. The brainstem is the part of the brain that connects the brain with the spinal cord. http://purl.obolibrary.org/obo/GO_0003365 establishment of cell polarity involved in ameboidal cell migration http://purl.obolibrary.org/obo/GO_0030010 establishment of cell polarity The specification and formation of anisotropic intracellular organization that contributes to the self-propelled directed movement of an ameboid cell. http://purl.obolibrary.org/obo/GO_0003367 cell-cell adhesion involved in ameboidal cell migration http://purl.obolibrary.org/obo/GO_0098609 cell-cell adhesion The attachment of one ameboid cell to another that contributes to the establishment of cell polarity that is part of the directed movement of one of the cells. http://purl.obolibrary.org/obo/GO_0003371 establishment or maintenance of cytoskeleton polarity involved in ameboidal cell migration http://purl.obolibrary.org/obo/GO_0030952 establishment or maintenance of cytoskeleton polarity Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures that contribute to the cell polarity of a migrating ameboid cell. http://purl.obolibrary.org/obo/GO_0003379 establishment of cell polarity involved in gastrulation cell migration http://purl.obolibrary.org/obo/GO_0003365 establishment of cell polarity involved in ameboidal cell migration The specification and formation of anisotropic intracellular organization that contributes to the self-propelled directed movement of an ameboid cell taking part in gastrulation. http://purl.obolibrary.org/obo/GO_0003380 establishment or maintenance of cytoskeleton polarity involved in gastrulation http://purl.obolibrary.org/obo/GO_0003371 establishment or maintenance of cytoskeleton polarity involved in ameboidal cell migration Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures that contribute to the cell polarity of a migrating ameboid cell taking part in gastrulation. http://purl.obolibrary.org/obo/GO_0003381 epithelial cell morphogenesis involved in gastrulation http://purl.obolibrary.org/obo/GO_0003382 epithelial cell morphogenesis The change in form that occurs when an epithelial cell progresses from it initial formation to its mature state, contributing to the process of gastrulation. http://purl.obolibrary.org/obo/GO_0003382 epithelial cell morphogenesis http://purl.obolibrary.org/obo/GO_0000902 cell morphogenesis The change in form that occurs when an epithelial cell progresses from its initial formation to its mature state. http://purl.obolibrary.org/obo/GO_0003403 optic vesicle formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The developmental process pertaining to the initial formation of the optic vesicle from the lateral wall of the forebrain. This process begins with the specific processes that contribute to the appearance of the vesicle and ends when the vesicle has evaginated. The optic vesicle is the evagination of neurectoderm that precedes formation of the optic cup. http://purl.obolibrary.org/obo/GO_0003404 optic vesicle morphogenesis http://purl.obolibrary.org/obo/GO_0048729 tissue morphogenesis The developmental process pertaining to the formation and shaping of the optic vesicle. This process begins with the specific processes that contribute to the appearance of the vesicle and ends when the vesicle has evaginated. The optic vesicle is the evagination of neurectoderm that precedes formation of the optic cup. http://purl.obolibrary.org/obo/GO_0003406 retinal pigment epithelium development http://purl.obolibrary.org/obo/GO_0060429 epithelium development The progression of the retinal pigment epithelium over time, from its initial formation to the mature structure. The retinal pigment epithelium is the melanin-containing layer of cells between the retina and the choroid that absorbs scattered and reflected light and removes waste products produced by the photoreceptor cells. http://purl.obolibrary.org/obo/GO_0003407 neural retina development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells. http://purl.obolibrary.org/obo/GO_0003413 chondrocyte differentiation involved in endochondral bone morphogenesis http://purl.obolibrary.org/obo/GO_0002062 chondrocyte differentiation The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the development of a bone. A chondrocyte is a polymorphic cell that forms cartilage. http://purl.obolibrary.org/obo/GO_0003415 chondrocyte hypertrophy http://purl.obolibrary.org/obo/GO_0048588 developmental cell growth The growth of a chondrocyte, where growth contributes to the progression of the chondrocyte over time. http://purl.obolibrary.org/obo/GO_0003416 endochondral bone growth http://purl.obolibrary.org/obo/GO_0098868 bone growth The increase in size or mass of an endochondral bone that contributes to the shaping of the bone. http://purl.obolibrary.org/obo/GO_0003417 growth plate cartilage development http://purl.obolibrary.org/obo/GO_0061448 connective tissue development The process whose specific outcome is the progression of the cartilage that will provide a scaffold for mineralization of endochondral bones as they elongate or grow. http://purl.obolibrary.org/obo/GO_0003418 growth plate cartilage chondrocyte differentiation http://purl.obolibrary.org/obo/GO_0003413 chondrocyte differentiation involved in endochondral bone morphogenesis The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the growth of a bone. A chondrocyte is a polymorphic cell that forms cartilage. http://purl.obolibrary.org/obo/GO_0003422 growth plate cartilage morphogenesis http://purl.obolibrary.org/obo/GO_0060536 cartilage morphogenesis The process in which the anatomical structures of growth plate cartilage are generated and organized. http://purl.obolibrary.org/obo/GO_0003429 growth plate cartilage chondrocyte morphogenesis http://purl.obolibrary.org/obo/GO_0090171 chondrocyte morphogenesis The process in which the structures of a chondrocyte in the growth plate cartilage are generated and organized. http://purl.obolibrary.org/obo/GO_0003430 growth plate cartilage chondrocyte growth http://purl.obolibrary.org/obo/GO_0060560 developmental growth involved in morphogenesis The growth of a growth plate cartilage chondrocyte, where growth contributes to the progression of the chondrocyte over time from one condition to another. http://purl.obolibrary.org/obo/GO_0003431 growth plate cartilage chondrocyte development http://purl.obolibrary.org/obo/GO_0003433 chondrocyte development involved in endochondral bone morphogenesis The progression of a growth plate cartilage chondrocyte over time from after its fate commitment to the mature cell. http://purl.obolibrary.org/obo/GO_0003433 chondrocyte development involved in endochondral bone morphogenesis http://purl.obolibrary.org/obo/GO_0002063 chondrocyte development The progression of a chondrocyte over time from after its commitment to its mature state where the chondrocyte will contribute to the shaping of an endochondral bone. http://purl.obolibrary.org/obo/GO_0003676 nucleic acid binding http://purl.obolibrary.org/obo/GO_0005488 binding Binding to a nucleic acid. http://purl.obolibrary.org/obo/GO_0003677 DNA binding http://purl.obolibrary.org/obo/GO_0003676 nucleic acid binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). http://purl.obolibrary.org/obo/GO_0003682 chromatin binding http://purl.obolibrary.org/obo/GO_0005488 binding Binding to chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase. http://purl.obolibrary.org/obo/GO_0003723 RNA binding http://purl.obolibrary.org/obo/GO_0003676 nucleic acid binding Binding to an RNA molecule or a portion thereof. http://purl.obolibrary.org/obo/GO_0003774 cytoskeletal motor activity http://purl.obolibrary.org/obo/GO_0003674 molecular_function Generation of force resulting in movement, for example along a microfilament or microtubule, or in torque resulting in membrane scission or rotation of a flagellum. The energy required is obtained either from the hydrolysis of a nucleoside triphosphate or by an electrochemical proton gradient (proton-motive force). http://purl.obolibrary.org/obo/GO_0003777 microtubule motor activity http://purl.obolibrary.org/obo/GO_0140657 ATP-dependent activity A motor activity that generates movement along a microtubule, driven by ATP hydrolysis. http://purl.obolibrary.org/obo/GO_0003824 catalytic activity http://purl.obolibrary.org/obo/GO_0003674 molecular_function Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic. http://purl.obolibrary.org/obo/GO_0004888 transmembrane signaling receptor activity http://purl.obolibrary.org/obo/GO_0038023 signaling receptor activity Combining with an extracellular or intracellular signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity or state as part of signal transduction. http://purl.obolibrary.org/obo/GO_0004896 cytokine receptor activity http://purl.obolibrary.org/obo/GO_0140375 immune receptor activity Combining with a cytokine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. http://purl.obolibrary.org/obo/GO_0004930 G protein-coupled receptor activity http://purl.obolibrary.org/obo/GO_0004888 transmembrane signaling receptor activity Combining with an extracellular signal and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. http://purl.obolibrary.org/obo/GO_0004983 neuropeptide Y receptor activity http://purl.obolibrary.org/obo/GO_0008188 neuropeptide receptor activity Combining with neuropeptide Y to initiate a change in cell activity. http://purl.obolibrary.org/obo/GO_0004993 G protein-coupled serotonin receptor activity http://purl.obolibrary.org/obo/GO_0008227 G protein-coupled amine receptor activity Combining with the biogenic amine serotonin and transmitting the signal across the membrane by activating an associated G-protein. Serotonin (5-hydroxytryptamine) is a neurotransmitter and hormone found in vertebrates and invertebrates. http://purl.obolibrary.org/obo/GO_0005102 signaling receptor binding http://purl.obolibrary.org/obo/GO_0005515 protein binding Binding to one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function. http://purl.obolibrary.org/obo/GO_0005126 cytokine receptor binding http://purl.obolibrary.org/obo/GO_0005102 signaling receptor binding Binding to a cytokine receptor. http://purl.obolibrary.org/obo/GO_0005488 binding http://purl.obolibrary.org/obo/GO_0003674 molecular_function The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule. http://purl.obolibrary.org/obo/GO_0005515 protein binding http://purl.obolibrary.org/obo/GO_0005488 binding Binding to a protein. http://purl.obolibrary.org/obo/GO_0005622 intracellular anatomical structure http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure A component of a cell contained within (but not including) the plasma membrane. In eukaryotes it includes the nucleus and cytoplasm. http://purl.obolibrary.org/obo/GO_0005634 nucleus http://purl.obolibrary.org/obo/GO_0043231 intracellular membrane-bounded organelle A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. http://purl.obolibrary.org/obo/GO_0005694 chromosome http://purl.obolibrary.org/obo/GO_0043232 intracellular membraneless organelle A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information. http://purl.obolibrary.org/obo/GO_0005737 cytoplasm http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. http://purl.obolibrary.org/obo/GO_0005739 mitochondrion http://purl.obolibrary.org/obo/GO_0043231 intracellular membrane-bounded organelle A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. http://purl.obolibrary.org/obo/GO_0005741 mitochondrial outer membrane http://purl.obolibrary.org/obo/GO_0031968 organelle outer membrane The outer, i.e. cytoplasm-facing, lipid bilayer of the mitochondrial envelope. http://purl.obolibrary.org/obo/GO_0005764 lysosome http://purl.obolibrary.org/obo/GO_0000323 lytic vacuole A small lytic vacuole that has cell cycle-independent morphology found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions. http://purl.obolibrary.org/obo/GO_0005773 vacuole http://purl.obolibrary.org/obo/GO_0043231 intracellular membrane-bounded organelle A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol. http://purl.obolibrary.org/obo/GO_0005774 vacuolar membrane http://purl.obolibrary.org/obo/GO_0098588 bounding membrane of organelle The lipid bilayer surrounding the vacuole and separating its contents from the cytoplasm of the cell. http://purl.obolibrary.org/obo/GO_0005775 vacuolar lumen http://purl.obolibrary.org/obo/GO_0070013 intracellular organelle lumen The volume enclosed within the vacuolar membrane. http://purl.obolibrary.org/obo/GO_0005815 microtubule organizing center http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure An intracellular structure that can catalyze gamma-tubulin-dependent microtubule nucleation and that can anchor microtubules by interacting with their minus ends, plus ends or sides. http://purl.obolibrary.org/obo/GO_0005829 cytosol http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. http://purl.obolibrary.org/obo/GO_0005840 ribosome http://purl.obolibrary.org/obo/GO_0043232 intracellular membraneless organelle An intracellular organelle, about 200 A in diameter, consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA). It consists of two subunits, one large and one small, each containing only protein and RNA. Both the ribosome and its subunits are characterized by their sedimentation coefficients, expressed in Svedberg units (symbol: S). Hence, the prokaryotic ribosome (70S) comprises a large (50S) subunit and a small (30S) subunit, while the eukaryotic ribosome (80S) comprises a large (60S) subunit and a small (40S) subunit. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site). Ribosomes from prokaryotes, eukaryotes, mitochondria, and chloroplasts have characteristically distinct ribosomal proteins. http://purl.obolibrary.org/obo/GO_0005881 cytoplasmic microtubule http://purl.obolibrary.org/obo/GO_0005874 microtubule Any microtubule in the cytoplasm of a cell. http://purl.obolibrary.org/obo/GO_0005886 plasma membrane http://purl.obolibrary.org/obo/GO_0016020 membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. http://purl.obolibrary.org/obo/GO_0005976 polysaccharide metabolic process http://purl.obolibrary.org/obo/GO_0043170 macromolecule metabolic process The chemical reactions and pathways involving a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically. http://purl.obolibrary.org/obo/GO_0005977 glycogen metabolic process http://purl.obolibrary.org/obo/GO_0044042 glucan metabolic process The chemical reactions and pathways involving glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues in alpha-(1->4) glycosidic linkage, joined together by alpha-(1->6) glycosidic linkages. http://purl.obolibrary.org/obo/GO_0006259 DNA metabolic process http://purl.obolibrary.org/obo/GO_0090304 nucleic acid metabolic process Any cellular metabolic process involving deoxyribonucleic acid. This is one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides. http://purl.obolibrary.org/obo/GO_0006308 DNA catabolic process http://purl.obolibrary.org/obo/GO_0141188 nucleic acid catabolic process The cellular DNA metabolic process resulting in the breakdown of DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long unbranched macromolecule formed from one or two strands of linked deoxyribonucleotides, the 3'-phosphate group of each constituent deoxyribonucleotide being joined in 3',5'-phosphodiester linkage to the 5'-hydroxyl group of the deoxyribose moiety of the next one. http://purl.obolibrary.org/obo/GO_0006310 DNA recombination http://purl.obolibrary.org/obo/GO_0006259 DNA metabolic process Any process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Interchromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction. http://purl.obolibrary.org/obo/GO_0006325 chromatin organization http://purl.obolibrary.org/obo/GO_0016043 cellular component organization The assembly or remodeling of chromatin composed of DNA complexed with histones, other associated proteins, and sometimes RNA. http://purl.obolibrary.org/obo/GO_0006401 RNA catabolic process http://purl.obolibrary.org/obo/GO_0141188 nucleic acid catabolic process The chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. http://purl.obolibrary.org/obo/GO_0006412 translation http://purl.obolibrary.org/obo/GO_0009059 macromolecule biosynthetic process The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome. http://purl.obolibrary.org/obo/GO_0006413 translational initiation http://purl.obolibrary.org/obo/GO_0008152 metabolic process The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA. http://purl.obolibrary.org/obo/GO_0006414 translational elongation http://purl.obolibrary.org/obo/GO_0009059 macromolecule biosynthetic process The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis. http://purl.obolibrary.org/obo/GO_0006415 translational termination http://purl.obolibrary.org/obo/GO_0032984 protein-containing complex disassembly The process resulting in the release of a polypeptide chain from the ribosome, usually in response to a termination codon (UAA, UAG, or UGA in the universal genetic code). http://purl.obolibrary.org/obo/GO_0006508 proteolysis http://purl.obolibrary.org/obo/GO_0019538 protein metabolic process The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds. http://purl.obolibrary.org/obo/GO_0006520 amino acid metabolic process http://purl.obolibrary.org/obo/GO_0044238 primary metabolic process The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups. http://purl.obolibrary.org/obo/GO_0006521 regulation of amino acid metabolic process http://purl.obolibrary.org/obo/GO_0080090 regulation of primary metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amino acids. http://purl.obolibrary.org/obo/GO_0006547 L-histidine metabolic process http://purl.obolibrary.org/obo/GO_0170033 L-amino acid metabolic process The chemical reactions and pathways involving L-histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid. http://purl.obolibrary.org/obo/GO_0006575 modified amino acid metabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process The chemical reactions and pathways involving compounds derived from amino acids, organic acids containing one or more amino substituents. http://purl.obolibrary.org/obo/GO_0006576 biogenic amine metabolic process http://purl.obolibrary.org/obo/GO_0009308 amine metabolic process The chemical reactions and pathways occurring at the level of individual cells involving any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters. http://purl.obolibrary.org/obo/GO_0006581 acetylcholine catabolic process http://purl.obolibrary.org/obo/GO_0009056 catabolic process The chemical reactions and pathways resulting in the breakdown of acetylcholine, the acetic acid ester of the organic base choline. http://purl.obolibrary.org/obo/GO_0006606 protein import into nucleus http://purl.obolibrary.org/obo/GO_0006886 intracellular protein transport The directed movement of a protein from the cytoplasm to the nucleus. http://purl.obolibrary.org/obo/GO_0006631 fatty acid metabolic process http://purl.obolibrary.org/obo/GO_0032787 monocarboxylic acid metabolic process The chemical reactions and pathways involving fatty acids, aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis. http://purl.obolibrary.org/obo/GO_0006633 fatty acid biosynthetic process http://purl.obolibrary.org/obo/GO_0072330 monocarboxylic acid biosynthetic process The chemical reactions and pathways resulting in the formation of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes. http://purl.obolibrary.org/obo/GO_0006687 glycosphingolipid metabolic process http://purl.obolibrary.org/obo/GO_0006665 sphingolipid metabolic process The chemical reactions and pathways involving glycosphingolipids, any compound with residues of sphingoid and at least one monosaccharide. http://purl.obolibrary.org/obo/GO_0006688 glycosphingolipid biosynthetic process http://purl.obolibrary.org/obo/GO_0006687 glycosphingolipid metabolic process The chemical reactions and pathways resulting in the formation of a glycosphingolipid, a compound composed of a ceramide backbone covalently linked to at least one carbohydrate moiety. http://purl.obolibrary.org/obo/GO_0006790 sulfur compound metabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process The chemical reactions and pathways involving the nonmetallic element sulfur or compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione. http://purl.obolibrary.org/obo/GO_0006814 sodium ion transport http://purl.obolibrary.org/obo/GO_0030001 metal ion transport The directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0006816 calcium ion transport http://purl.obolibrary.org/obo/GO_0030001 metal ion transport The directed movement of calcium (Ca) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0006833 water transport http://purl.obolibrary.org/obo/GO_0042044 fluid transport The directed movement of water (H2O) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0006836 neurotransmitter transport http://purl.obolibrary.org/obo/GO_0006810 transport The directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Neurotransmitters are any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell. http://purl.obolibrary.org/obo/GO_0006837 serotonin transport http://purl.obolibrary.org/obo/GO_0015850 organic hydroxy compound transport The directed movement of serotonin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Serotonin (5-hydroxytryptamine) is a monoamine neurotransmitter occurring in the peripheral and central nervous systems. http://purl.obolibrary.org/obo/GO_0006839 mitochondrial transport http://purl.obolibrary.org/obo/GO_0046907 intracellular transport Transport of substances into, out of or within a mitochondrion. http://purl.obolibrary.org/obo/GO_0006865 amino acid transport http://purl.obolibrary.org/obo/GO_0006810 transport The directed movement of amino acids, organic acids containing one or more amino substituents, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0006869 lipid transport http://purl.obolibrary.org/obo/GO_0006810 transport The directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Lipids are compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. http://purl.obolibrary.org/obo/GO_0006886 intracellular protein transport http://purl.obolibrary.org/obo/GO_0046907 intracellular transport The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell. http://purl.obolibrary.org/obo/GO_0006909 phagocytosis http://purl.obolibrary.org/obo/GO_0006897 endocytosis A vesicle-mediated transport process that results in the engulfment of external particulate material by phagocytes and their delivery to the lysosome. The particles are initially contained within phagocytic vacuoles (phagosomes), which then fuse with primary lysosomes to effect digestion of the particles. http://purl.obolibrary.org/obo/GO_0006913 nucleocytoplasmic transport http://purl.obolibrary.org/obo/GO_0051169 nuclear transport The directed movement of molecules between the nucleus and the cytoplasm. http://purl.obolibrary.org/obo/GO_0006915 apoptotic process http://purl.obolibrary.org/obo/GO_0012501 programmed cell death A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died. http://purl.obolibrary.org/obo/GO_0006925 inflammatory cell apoptotic process http://purl.obolibrary.org/obo/GO_0006915 apoptotic process Any apoptotic process in an inflammatory cell, any cell participating in the inflammatory response to a foreign substance e.g. neutrophil, macrophage. http://purl.obolibrary.org/obo/GO_0006940 regulation of smooth muscle contraction http://purl.obolibrary.org/obo/GO_0006937 regulation of muscle contraction Any process that modulates the frequency, rate or extent of smooth muscle contraction. http://purl.obolibrary.org/obo/GO_0006941 striated muscle contraction http://purl.obolibrary.org/obo/GO_0006936 muscle contraction A process in which force is generated within striated muscle tissue, resulting in the shortening of the muscle. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Striated muscle is a type of muscle in which the repeating units (sarcomeres) of the contractile myofibrils are arranged in registry throughout the cell, resulting in transverse or oblique striations observable at the level of the light microscope. http://purl.obolibrary.org/obo/GO_0006949 syncytium formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane. Syncytia are normally derived from single cells that fuse or fail to complete cell division. http://purl.obolibrary.org/obo/GO_0006950 response to stress http://purl.obolibrary.org/obo/GO_0050896 response to stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). http://purl.obolibrary.org/obo/GO_0006952 defense response http://purl.obolibrary.org/obo/GO_0006950 response to stress Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack. http://purl.obolibrary.org/obo/GO_0006954 inflammatory response http://purl.obolibrary.org/obo/GO_0006952 defense response The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages. http://purl.obolibrary.org/obo/GO_0006955 immune response http://purl.obolibrary.org/obo/GO_0002376 immune system process Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. http://purl.obolibrary.org/obo/GO_0006959 humoral immune response http://purl.obolibrary.org/obo/GO_0006955 immune response An immune response mediated through a body fluid. http://purl.obolibrary.org/obo/GO_0006979 response to oxidative stress http://purl.obolibrary.org/obo/GO_0006950 response to stress Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals. http://purl.obolibrary.org/obo/GO_0006997 nucleus organization http://purl.obolibrary.org/obo/GO_0006996 organelle organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleus. http://purl.obolibrary.org/obo/GO_0007005 mitochondrion organization http://purl.obolibrary.org/obo/GO_0006996 organelle organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrion; includes mitochondrial morphogenesis and distribution, and replication of the mitochondrial genome as well as synthesis of new mitochondrial components. http://purl.obolibrary.org/obo/GO_0007009 plasma membrane organization http://purl.obolibrary.org/obo/GO_0061024 membrane organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the plasma membrane. http://purl.obolibrary.org/obo/GO_0007010 cytoskeleton organization http://purl.obolibrary.org/obo/GO_0006996 organelle organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures. http://purl.obolibrary.org/obo/GO_0007017 microtubule-based process http://purl.obolibrary.org/obo/GO_0009987 cellular process Any cellular process that depends upon or alters the microtubule cytoskeleton, that part of the cytoskeleton comprising microtubules and their associated proteins. http://purl.obolibrary.org/obo/GO_0007018 microtubule-based movement http://purl.obolibrary.org/obo/GO_0007017 microtubule-based process A microtubule-based process that results in the movement of organelles, other microtubules, or other cellular components. Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules. http://purl.obolibrary.org/obo/GO_0007033 vacuole organization http://purl.obolibrary.org/obo/GO_0006996 organelle organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vacuole. http://purl.obolibrary.org/obo/GO_0007040 lysosome organization http://purl.obolibrary.org/obo/GO_0080171 lytic vacuole organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lysosome. A lysosome is a cytoplasmic, membrane-bounded organelle that is found in most animal cells and that contains a variety of hydrolases. http://purl.obolibrary.org/obo/GO_0007043 cell-cell junction assembly http://purl.obolibrary.org/obo/GO_0045216 cell-cell junction organization The aggregation, arrangement and bonding together of a set of components to form a junction between cells. http://purl.obolibrary.org/obo/GO_0007049 cell cycle http://purl.obolibrary.org/obo/GO_0009987 cellular process The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division. http://purl.obolibrary.org/obo/GO_0007097 nuclear migration http://purl.obolibrary.org/obo/GO_0051656 establishment of organelle localization The directed movement of the nucleus to a specific location within a cell. http://purl.obolibrary.org/obo/GO_0007154 cell communication http://purl.obolibrary.org/obo/GO_0009987 cellular process Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. http://purl.obolibrary.org/obo/GO_0007155 cell adhesion http://purl.obolibrary.org/obo/GO_0009987 cellular process The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules. http://purl.obolibrary.org/obo/GO_0007165 signal transduction http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell. http://purl.obolibrary.org/obo/GO_0007166 cell surface receptor signaling pathway http://purl.obolibrary.org/obo/GO_0007165 signal transduction The series of molecular signals initiated by an extracellular ligand binding to a receptor located on the cell surface. The pathway ends with regulation of a downstream cellular process, e.g. transcription. http://purl.obolibrary.org/obo/GO_0007186 G protein-coupled receptor signaling pathway http://purl.obolibrary.org/obo/GO_0007165 signal transduction The series of molecular signals initiated by a ligand binding to its receptor, in which the activated receptor promotes the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, and ends with regulation of a downstream cellular process. The pathway can start from the plasma membrane, Golgi or nuclear membrane. http://purl.obolibrary.org/obo/GO_0007267 cell-cell signaling http://purl.obolibrary.org/obo/GO_0023052 signaling Any process that mediates the transfer of information from one cell to another. This process includes signal transduction in the receiving cell and, where applicable, release of a ligand and any processes that actively facilitate its transport and presentation to the receiving cell. Examples include signaling via soluble ligands, via cell adhesion molecules and via gap junctions. http://purl.obolibrary.org/obo/GO_0007269 neurotransmitter secretion http://purl.obolibrary.org/obo/GO_0006836 neurotransmitter transport The regulated release of neurotransmitter from the presynapse into the synaptic cleft via calcium-regulated exocytosis during synaptic transmission. http://purl.obolibrary.org/obo/GO_0007271 synaptic transmission, cholinergic http://purl.obolibrary.org/obo/GO_0007268 chemical synaptic transmission The vesicular release of acetylcholine from a presynapse, across a chemical synapse, the subsequent activation of dopamine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse. http://purl.obolibrary.org/obo/GO_0007275 multicellular organism development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). http://purl.obolibrary.org/obo/GO_0007286 spermatid development http://purl.obolibrary.org/obo/GO_0007281 germ cell development The process whose specific outcome is the progression of a spermatid over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0007369 gastrulation http://purl.obolibrary.org/obo/GO_0048598 embryonic morphogenesis A complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals. The details of gastrulation vary from species to species, but usually result in the formation of the three primary germ layers, ectoderm, mesoderm and endoderm. http://purl.obolibrary.org/obo/GO_0007389 pattern specification process http://purl.obolibrary.org/obo/GO_0032501 multicellular organismal process Any developmental process that results in the creation of defined areas or spaces within an organism to which cells respond and eventually are instructed to differentiate. http://purl.obolibrary.org/obo/GO_0007398 ectoderm development http://purl.obolibrary.org/obo/GO_0009888 tissue development The process whose specific outcome is the progression of the ectoderm over time, from its formation to the mature structure. In animal embryos, the ectoderm is the outer germ layer of the embryo, formed during gastrulation. http://purl.obolibrary.org/obo/GO_0007405 neuroblast proliferation http://purl.obolibrary.org/obo/GO_0061351 neural precursor cell proliferation The expansion of a neuroblast population by cell division. A neuroblast is any cell that will divide and give rise to a neuron. http://purl.obolibrary.org/obo/GO_0007423 sensory organ development http://purl.obolibrary.org/obo/GO_0048513 animal organ development The process whose specific outcome is the progression of sensory organs over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0007492 endoderm development http://purl.obolibrary.org/obo/GO_0009888 tissue development The process whose specific outcome is the progression of the endoderm over time, from its formation to the mature structure. The endoderm is the innermost germ layer that develops into the gastrointestinal tract, the lungs and associated tissues. http://purl.obolibrary.org/obo/GO_0007507 heart development http://purl.obolibrary.org/obo/GO_0048513 animal organ development The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. http://purl.obolibrary.org/obo/GO_0007519 skeletal muscle tissue development http://purl.obolibrary.org/obo/GO_0014706 striated muscle tissue development The developmental sequence of events leading to the formation of adult skeletal muscle tissue. The main events are: the fusion of myoblasts to form myotubes that increase in size by further fusion to them of myoblasts, the formation of myofibrils within their cytoplasm and the establishment of functional neuromuscular junctions with motor neurons. At this stage they can be regarded as mature muscle fibers. http://purl.obolibrary.org/obo/GO_0007585 respiratory gaseous exchange by respiratory system http://purl.obolibrary.org/obo/GO_0032501 multicellular organismal process The process of gaseous exchange between an organism and its environment. In plants, microorganisms, and many small animals, air or water makes direct contact with the organism's cells or tissue fluids, and the processes of diffusion supply the organism with dioxygen (O2) and remove carbon dioxide (CO2). In larger animals the efficiency of gaseous exchange is improved by specialized respiratory organs, such as lungs and gills, which are ventilated by breathing mechanisms. http://purl.obolibrary.org/obo/GO_0007610 behavior http://purl.obolibrary.org/obo/GO_0032501 multicellular organismal process The internally coordinated responses (actions or inactions) of animals (individuals or groups) to internal or external stimuli, via a mechanism that involves nervous system activity. http://purl.obolibrary.org/obo/GO_0008016 regulation of heart contraction http://purl.obolibrary.org/obo/GO_1903522 regulation of blood circulation Any process that modulates the frequency, rate or extent of heart contraction. Heart contraction is the process in which the heart decreases in volume in a characteristic way to propel blood through the body. http://purl.obolibrary.org/obo/GO_0008092 cytoskeletal protein binding http://purl.obolibrary.org/obo/GO_0005515 protein binding Binding to a protein component of a cytoskeleton (actin, microtubule, or intermediate filament cytoskeleton). http://purl.obolibrary.org/obo/GO_0008094 ATP-dependent activity, acting on DNA http://purl.obolibrary.org/obo/GO_0140657 ATP-dependent activity Catalytic activity that acts to modify DNA, driven by ATP hydrolysis. http://purl.obolibrary.org/obo/GO_0008134 transcription factor binding http://purl.obolibrary.org/obo/GO_0005515 protein binding Binding to a transcription factor, a protein required to initiate or regulate transcription. http://purl.obolibrary.org/obo/GO_0008186 ATP-dependent activity, acting on RNA http://purl.obolibrary.org/obo/GO_0140657 ATP-dependent activity Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction requires the presence of RNA, and it drives another reaction. http://purl.obolibrary.org/obo/GO_0008188 neuropeptide receptor activity http://purl.obolibrary.org/obo/GO_0008528 G protein-coupled peptide receptor activity Combining with a neuropeptide to initiate a change in cell activity. http://purl.obolibrary.org/obo/GO_0008206 bile acid metabolic process http://purl.obolibrary.org/obo/GO_0032787 monocarboxylic acid metabolic process The chemical reactions and pathways involving bile acids, a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine. http://purl.obolibrary.org/obo/GO_0008217 regulation of blood pressure http://purl.obolibrary.org/obo/GO_0065008 regulation of biological quality Any process that modulates the force with which blood travels through the circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure. http://purl.obolibrary.org/obo/GO_0008227 G protein-coupled amine receptor activity http://purl.obolibrary.org/obo/GO_0004930 G protein-coupled receptor activity Combining with an extracellular amine and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. http://purl.obolibrary.org/obo/GO_0008283 cell population proliferation http://purl.obolibrary.org/obo/GO_0009987 cellular process The multiplication or reproduction of cells, resulting in the expansion of a cell population. http://purl.obolibrary.org/obo/GO_0008284 positive regulation of cell population proliferation http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the rate or extent of cell proliferation. http://purl.obolibrary.org/obo/GO_0008289 lipid binding http://purl.obolibrary.org/obo/GO_0005488 binding Binding to a lipid. http://purl.obolibrary.org/obo/GO_0008306 associative learning http://purl.obolibrary.org/obo/GO_0007612 learning Learning by associating a stimulus (the cause) with a particular outcome (the effect). http://purl.obolibrary.org/obo/GO_0008324 monoatomic cation transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0015075 monoatomic ion transmembrane transporter activity Enables the transfer of cation from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0008348 negative regulation of antimicrobial humoral response http://purl.obolibrary.org/obo/GO_0032102 negative regulation of response to external stimulus Any process that stops, prevents, or reduces the frequency, rate, or extent of an antimicrobial humoral response. http://purl.obolibrary.org/obo/GO_0008519 ammonium channel activity http://purl.obolibrary.org/obo/GO_0015267 channel activity Enables the energy-independent facilitated diffusion of ammonium through a transmembrane aqueous pore or channel. http://purl.obolibrary.org/obo/GO_0008528 G protein-coupled peptide receptor activity http://purl.obolibrary.org/obo/GO_0004930 G protein-coupled receptor activity Combining with a peptide and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. http://purl.obolibrary.org/obo/GO_0008585 female gonad development http://purl.obolibrary.org/obo/GO_0008406 gonad development The process whose specific outcome is the progression of the female gonad over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0008652 amino acid biosynthetic process http://purl.obolibrary.org/obo/GO_0009058 biosynthetic process The chemical reactions and pathways resulting in the formation of amino acids, organic acids containing one or more amino substituents. http://purl.obolibrary.org/obo/GO_0009057 macromolecule catabolic process http://purl.obolibrary.org/obo/GO_0009056 catabolic process The chemical reactions and pathways resulting in the breakdown of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. http://purl.obolibrary.org/obo/GO_0009058 biosynthetic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process A cellular process consisting of the biochemical pathways by which a living organism synthesizes chemical substances. This typically represents the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones. http://purl.obolibrary.org/obo/GO_0009059 macromolecule biosynthetic process http://purl.obolibrary.org/obo/GO_0009058 biosynthetic process The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. http://purl.obolibrary.org/obo/GO_0009062 fatty acid catabolic process http://purl.obolibrary.org/obo/GO_0006631 fatty acid metabolic process The chemical reactions and pathways resulting in the breakdown of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes. http://purl.obolibrary.org/obo/GO_0009063 amino acid catabolic process http://purl.obolibrary.org/obo/GO_0009056 catabolic process The chemical reactions and pathways resulting in the breakdown of amino acids, organic acids containing one or more amino substituents. http://purl.obolibrary.org/obo/GO_0009073 aromatic amino acid family biosynthetic process http://purl.obolibrary.org/obo/GO_0046394 carboxylic acid biosynthetic process The chemical reactions and pathways resulting in the formation of aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan). http://purl.obolibrary.org/obo/GO_0009074 aromatic amino acid family catabolic process http://purl.obolibrary.org/obo/GO_0046395 carboxylic acid catabolic process The chemical reactions and pathways resulting in the breakdown of aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan). http://purl.obolibrary.org/obo/GO_0009306 protein secretion http://purl.obolibrary.org/obo/GO_0071692 protein localization to extracellular region The controlled release of proteins from a cell. http://purl.obolibrary.org/obo/GO_0009536 plastid http://purl.obolibrary.org/obo/GO_0043231 intracellular membrane-bounded organelle Any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid. http://purl.obolibrary.org/obo/GO_0009547 plastid ribosome http://purl.obolibrary.org/obo/GO_0000313 organellar ribosome A ribosome contained within a plastid. http://purl.obolibrary.org/obo/GO_0009593 detection of chemical stimulus http://purl.obolibrary.org/obo/GO_0051606 detection of stimulus The series of events in which a chemical stimulus is received by a cell and converted into a molecular signal. http://purl.obolibrary.org/obo/GO_0009605 response to external stimulus http://purl.obolibrary.org/obo/GO_0050896 response to stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus. http://purl.obolibrary.org/obo/GO_0009607 response to biotic stimulus http://purl.obolibrary.org/obo/GO_0050896 response to stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotic stimulus, a stimulus caused or produced by a living organism. http://purl.obolibrary.org/obo/GO_0009611 response to wounding http://purl.obolibrary.org/obo/GO_0006950 response to stress Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism. http://purl.obolibrary.org/obo/GO_0009617 response to bacterium http://purl.obolibrary.org/obo/GO_0051707 response to other organism Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a bacterium. http://purl.obolibrary.org/obo/GO_0009620 response to fungus http://purl.obolibrary.org/obo/GO_0051707 response to other organism Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a fungus. http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis http://purl.obolibrary.org/obo/GO_0032502 developmental process The process in which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form. http://purl.obolibrary.org/obo/GO_0009755 hormone-mediated signaling pathway http://purl.obolibrary.org/obo/GO_0007165 signal transduction The series of molecular signals mediated by the detection of a hormone. http://purl.obolibrary.org/obo/GO_0009791 post-embryonic development http://purl.obolibrary.org/obo/GO_0032501 multicellular organismal process The process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. See embryonic development. http://purl.obolibrary.org/obo/GO_0009792 embryo development ending in birth or egg hatching http://purl.obolibrary.org/obo/GO_0009790 embryo development The process whose specific outcome is the progression of an embryo over time, from zygote formation until the end of the embryonic life stage. The end of the embryonic life stage is organism-specific and may be somewhat arbitrary; for mammals it is usually considered to be birth, for insects the hatching of the first instar larva from the eggshell. http://purl.obolibrary.org/obo/GO_0009798 axis specification http://purl.obolibrary.org/obo/GO_0007389 pattern specification process The establishment, maintenance and elaboration of a pattern along a line or around a point. http://purl.obolibrary.org/obo/GO_0009880 embryonic pattern specification http://purl.obolibrary.org/obo/GO_0007389 pattern specification process The process that results in the patterns of cell differentiation that will arise in an embryo. http://purl.obolibrary.org/obo/GO_0009886 post-embryonic animal morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process, occurring after animal embryonic development, by which anatomical structures are generated and organized. http://purl.obolibrary.org/obo/GO_0009887 animal organ morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis Morphogenesis of an animal organ. An organ is defined as a tissue or set of tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. http://purl.obolibrary.org/obo/GO_0009888 tissue development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of a tissue over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0009913 epidermal cell differentiation http://purl.obolibrary.org/obo/GO_0030855 epithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of an epidermal cell, any of the cells making up the epidermis. http://purl.obolibrary.org/obo/GO_0009914 hormone transport http://purl.obolibrary.org/obo/GO_0010817 regulation of hormone levels The directed movement of hormones into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0009952 anterior/posterior pattern specification http://purl.obolibrary.org/obo/GO_0003002 regionalization The regionalization process in which specific areas of cell differentiation are determined along the anterior-posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism. http://purl.obolibrary.org/obo/GO_0009966 regulation of signal transduction http://purl.obolibrary.org/obo/GO_0048583 regulation of response to stimulus Any process that modulates the frequency, rate or extent of signal transduction. http://purl.obolibrary.org/obo/GO_0009967 positive regulation of signal transduction http://purl.obolibrary.org/obo/GO_0010647 positive regulation of cell communication Any process that activates or increases the frequency, rate or extent of signal transduction. http://purl.obolibrary.org/obo/GO_0009968 negative regulation of signal transduction http://purl.obolibrary.org/obo/GO_0010648 negative regulation of cell communication Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction. http://purl.obolibrary.org/obo/GO_0009987 cellular process http://purl.obolibrary.org/obo/GO_0008150 biological_process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. http://purl.obolibrary.org/obo/GO_0010001 glial cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a glial cell. http://purl.obolibrary.org/obo/GO_0010002 cardioblast differentiation http://purl.obolibrary.org/obo/GO_0048863 stem cell differentiation The process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. http://purl.obolibrary.org/obo/GO_0010463 mesenchymal cell proliferation http://purl.obolibrary.org/obo/GO_0008283 cell population proliferation The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets. http://purl.obolibrary.org/obo/GO_0010464 regulation of mesenchymal cell proliferation http://purl.obolibrary.org/obo/GO_0042127 regulation of cell population proliferation Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets. http://purl.obolibrary.org/obo/GO_0010467 gene expression http://purl.obolibrary.org/obo/GO_0009059 macromolecule biosynthetic process The process in which a gene's sequence is converted into a mature gene product (protein or RNA). This includes the production of an RNA transcript and its processing, as well as translation and maturation for protein-coding genes. http://purl.obolibrary.org/obo/GO_0010468 regulation of gene expression http://purl.obolibrary.org/obo/GO_0010556 regulation of macromolecule biosynthetic process Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA). http://purl.obolibrary.org/obo/GO_0010556 regulation of macromolecule biosynthetic process http://purl.obolibrary.org/obo/GO_0009889 regulation of biosynthetic process Any process that modulates the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. http://purl.obolibrary.org/obo/GO_0010557 positive regulation of macromolecule biosynthetic process http://purl.obolibrary.org/obo/GO_0009891 positive regulation of biosynthetic process Any process that increases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. http://purl.obolibrary.org/obo/GO_0010558 negative regulation of macromolecule biosynthetic process http://purl.obolibrary.org/obo/GO_0009890 negative regulation of biosynthetic process Any process that decreases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. http://purl.obolibrary.org/obo/GO_0010604 positive regulation of macromolecule metabolic process http://purl.obolibrary.org/obo/GO_0009893 positive regulation of metabolic process Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. http://purl.obolibrary.org/obo/GO_0010605 negative regulation of macromolecule metabolic process http://purl.obolibrary.org/obo/GO_0009892 negative regulation of metabolic process Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. http://purl.obolibrary.org/obo/GO_0010646 regulation of cell communication http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. http://purl.obolibrary.org/obo/GO_0010668 ectodermal cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features of an ectodermal cell. Differentiation includes the processes involved in commitment of a cell to a specific fate. http://purl.obolibrary.org/obo/GO_0010817 regulation of hormone levels http://purl.obolibrary.org/obo/GO_0065008 regulation of biological quality Any process that modulates the levels of hormone within an organism or a tissue. A hormone is any substance formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells in the same organism, upon which it has a specific regulatory action. http://purl.obolibrary.org/obo/GO_0010927 cellular component assembly involved in morphogenesis http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The cellular component assembly that is part of the initial shaping of the component during its developmental progression. http://purl.obolibrary.org/obo/GO_0010954 positive regulation of protein processing http://purl.obolibrary.org/obo/GO_1903319 positive regulation of protein maturation Any process that increases the rate, frequency or extent of protein maturation by peptide bond cleavage. http://purl.obolibrary.org/obo/GO_0010959 regulation of metal ion transport http://purl.obolibrary.org/obo/GO_0043269 regulation of monoatomic ion transport Any process that modulates the frequency, rate, or extent of metal ion transport. Metal ion transport is the directed movement of metal ions, any metal ion with an electric charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0012501 programmed cell death http://purl.obolibrary.org/obo/GO_0008219 cell death A process which begins when a cell receives an internal or external signal and activates a series of biochemical events (signaling pathway). The process ends with the death of the cell. http://purl.obolibrary.org/obo/GO_0014020 primary neural tube formation http://purl.obolibrary.org/obo/GO_0001838 embryonic epithelial tube formation The formation of the neural tube from an epithelial cell sheet (the neuroepithelium or neural plate). In primary neurulation, the cells surrounding the neural plate direct the neural plate cells to proliferate, invaginate, and pinch off from the surface to form a hollow epithelial tube. Primary neurulation is the typical mechanism of formation of the anterior neural tube. http://purl.obolibrary.org/obo/GO_0014032 neural crest cell development http://purl.obolibrary.org/obo/GO_0048864 stem cell development The process aimed at the progression of a neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell. http://purl.obolibrary.org/obo/GO_0014075 response to amine http://purl.obolibrary.org/obo/GO_1901698 response to nitrogen compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amine stimulus. An amine is a compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups. http://purl.obolibrary.org/obo/GO_0014706 striated muscle tissue development http://purl.obolibrary.org/obo/GO_0060537 muscle tissue development The process whose specific outcome is the progression of a striated muscle over time, from its formation to the mature structure. Striated muscle contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle. Skeletal muscle myoblasts fuse to form myotubes and eventually multinucleated muscle fibers. The fusion of cardiac cells is very rare and can only form binucleate cells. http://purl.obolibrary.org/obo/GO_0014896 muscle hypertrophy http://purl.obolibrary.org/obo/GO_0003012 muscle system process The muscle system process that results in enlargement or overgrowth of all or part of a muscle organ due to an increase in the size of its muscle cells. Physiological hypertrophy is a normal process during development (it stops in cardiac muscle after adolescence) and can also be brought on in response to demand. In athletes cardiac and skeletal muscles undergo hypertrophy stimulated by increasing muscle activity on exercise. Smooth muscle cells in the uterus undergo hypertrophy during pregnancy. http://purl.obolibrary.org/obo/GO_0014897 striated muscle hypertrophy http://purl.obolibrary.org/obo/GO_0014896 muscle hypertrophy The enlargement or overgrowth of all or part of an organ due to an increase in size of muscle cells without cell division. In the case of striated muscle, this happens due to the additional synthesis of sarcomeric proteins and assembly of myofibrils. http://purl.obolibrary.org/obo/GO_0015078 proton transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0008324 monoatomic cation transmembrane transporter activity Enables the transfer of a proton from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0015171 amino acid transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity Enables the transfer of amino acids from one side of a membrane to the other. Amino acids are organic molecules that contain an amino group and a carboxyl group. http://purl.obolibrary.org/obo/GO_0015175 neutral L-amino acid transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0015171 amino acid transmembrane transporter activity Enables the transfer of neutral L-amino acids from one side of a membrane to the other. Neutral amino acids have side chains with no charge at pH 7.3. http://purl.obolibrary.org/obo/GO_0015179 L-amino acid transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0015171 amino acid transmembrane transporter activity Enables the transfer of an L-amino acid from one side of a membrane to the other. L-amino acids are the L-enantiomers of amino acids. http://purl.obolibrary.org/obo/GO_0015216 purine nucleotide transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0015215 nucleotide transmembrane transporter activity Enables the transfer of a purine nucleotide, any compound consisting of a purine nucleoside esterified with (ortho)phosphate, from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0015291 secondary active transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022804 active transmembrane transporter activity Enables the transfer of a solute from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy, not direct ATP coupling. Secondary active transporters include symporters and antiporters. http://purl.obolibrary.org/obo/GO_0015464 acetylcholine receptor activity http://purl.obolibrary.org/obo/GO_0098960 postsynaptic neurotransmitter receptor activity Combining with an acetylcholine receptor ligand and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. http://purl.obolibrary.org/obo/GO_0015605 organophosphate ester transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity Enables the transfer of organophosphate esters from one side of a membrane to the other. Organophosphate esters are small organic molecules containing phosphate ester bonds. http://purl.obolibrary.org/obo/GO_0015629 actin cytoskeleton http://purl.obolibrary.org/obo/GO_0005856 cytoskeleton The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes. http://purl.obolibrary.org/obo/GO_0015630 microtubule cytoskeleton http://purl.obolibrary.org/obo/GO_0005856 cytoskeleton The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins. http://purl.obolibrary.org/obo/GO_0015698 inorganic anion transport http://purl.obolibrary.org/obo/GO_0006810 transport The directed movement of inorganic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Inorganic anions are atoms or small molecules with a negative charge which do not contain carbon in covalent linkage. http://purl.obolibrary.org/obo/GO_0015711 organic anion transport http://purl.obolibrary.org/obo/GO_0006810 transport The directed movement of organic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage. http://purl.obolibrary.org/obo/GO_0015748 organophosphate ester transport http://purl.obolibrary.org/obo/GO_0006810 transport The directed movement of organophosphate esters into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organophosphate esters are small organic molecules containing phosphate ester bonds. http://purl.obolibrary.org/obo/GO_0015804 neutral amino acid transport http://purl.obolibrary.org/obo/GO_0006865 amino acid transport The directed movement of neutral amino acids, amino acids with no net charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0015813 L-glutamate transmembrane transport http://purl.obolibrary.org/obo/GO_0051938 L-glutamate import The directed movement of L-glutamate across a membrane by means of some agent such as a transporter or a pore. http://purl.obolibrary.org/obo/GO_0015833 peptide transport http://purl.obolibrary.org/obo/GO_0006810 transport The directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0015865 purine nucleotide transport http://purl.obolibrary.org/obo/GO_0006862 nucleotide transport The directed movement of a purine nucleotide, any compound consisting of a purine nucleoside esterified with (ortho)phosphate, into, out of or within a cell. http://purl.obolibrary.org/obo/GO_0015908 fatty acid transport http://purl.obolibrary.org/obo/GO_0006869 lipid transport The directed movement of fatty acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Fatty acids are aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis. http://purl.obolibrary.org/obo/GO_0016049 cell growth http://purl.obolibrary.org/obo/GO_0040007 growth The process in which a cell irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present. http://purl.obolibrary.org/obo/GO_0016050 vesicle organization http://purl.obolibrary.org/obo/GO_0006996 organelle organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vesicle. http://purl.obolibrary.org/obo/GO_0016051 carbohydrate biosynthetic process http://purl.obolibrary.org/obo/GO_0009058 biosynthetic process The chemical reactions and pathways resulting in the formation of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. http://purl.obolibrary.org/obo/GO_0016052 carbohydrate catabolic process http://purl.obolibrary.org/obo/GO_0009056 catabolic process The chemical reactions and pathways resulting in the breakdown of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. http://purl.obolibrary.org/obo/GO_0016064 immunoglobulin mediated immune response http://purl.obolibrary.org/obo/GO_0019724 B cell mediated immunity An immune response mediated by immunoglobulins, whether cell-bound or in solution. http://purl.obolibrary.org/obo/GO_0016070 RNA metabolic process http://purl.obolibrary.org/obo/GO_0090304 nucleic acid metabolic process The cellular chemical reactions and pathways involving RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. http://purl.obolibrary.org/obo/GO_0016331 morphogenesis of embryonic epithelium http://purl.obolibrary.org/obo/GO_0048598 embryonic morphogenesis The process in which the anatomical structures of embryonic epithelia are generated and organized. http://purl.obolibrary.org/obo/GO_0016358 dendrite development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the dendrite over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0016444 somatic cell DNA recombination http://purl.obolibrary.org/obo/GO_0006310 DNA recombination Recombination occurring within or between DNA molecules in somatic cells. http://purl.obolibrary.org/obo/GO_0016445 somatic diversification of immunoglobulins http://purl.obolibrary.org/obo/GO_0002200 somatic diversification of immune receptors The somatic process that results in the generation of sequence diversity of immunoglobulins. http://purl.obolibrary.org/obo/GO_0016446 somatic hypermutation of immunoglobulin genes http://purl.obolibrary.org/obo/GO_0016445 somatic diversification of immunoglobulins Mutations occurring somatically that result in amino acid changes in the rearranged V regions of immunoglobulins. http://purl.obolibrary.org/obo/GO_0016447 somatic recombination of immunoglobulin gene segments http://purl.obolibrary.org/obo/GO_0016445 somatic diversification of immunoglobulins The process in which immunoglobulin genes are formed through recombination of the germline genetic elements, as known as immunoglobulin gene segments, within a single locus. http://purl.obolibrary.org/obo/GO_0016462 pyrophosphatase activity http://purl.obolibrary.org/obo/GO_0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides Catalysis of the hydrolysis of a pyrophosphate bond (diphosphate bond) between two phosphate groups. http://purl.obolibrary.org/obo/GO_0016477 cell migration http://purl.obolibrary.org/obo/GO_0048870 cell motility The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues. http://purl.obolibrary.org/obo/GO_0016485 protein processing http://purl.obolibrary.org/obo/GO_0006508 proteolysis Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein. Protein maturation is the process leading to the attainment of the full functional capacity of a protein. http://purl.obolibrary.org/obo/GO_0016486 peptide hormone processing http://purl.obolibrary.org/obo/GO_0140448 signaling receptor ligand precursor processing The generation of a mature peptide hormone by posttranslational processing of a prohormone. http://purl.obolibrary.org/obo/GO_0016502 nucleotide receptor activity http://purl.obolibrary.org/obo/GO_0004888 transmembrane signaling receptor activity Combining with a nucleotide and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. A nucleotide is a compound that consists of a nucleoside esterified with a phosphate molecule. http://purl.obolibrary.org/obo/GO_0016740 transferase activity http://purl.obolibrary.org/obo/GO_0003824 catalytic activity Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2. http://purl.obolibrary.org/obo/GO_0016755 aminoacyltransferase activity http://purl.obolibrary.org/obo/GO_0016746 acyltransferase activity Catalysis of the transfer of an amino-acyl group from one compound (donor) to another (acceptor). http://purl.obolibrary.org/obo/GO_0016787 hydrolase activity http://purl.obolibrary.org/obo/GO_0003824 catalytic activity Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. http://purl.obolibrary.org/obo/GO_0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides http://purl.obolibrary.org/obo/GO_0016817 hydrolase activity, acting on acid anhydrides Catalysis of the hydrolysis of any acid anhydride which contains phosphorus. http://purl.obolibrary.org/obo/GO_0016853 isomerase activity http://purl.obolibrary.org/obo/GO_0003824 catalytic activity Catalysis of the geometric or structural changes within one molecule. Isomerase is the systematic name for any enzyme of EC class 5. http://purl.obolibrary.org/obo/GO_0016887 ATP hydrolysis activity http://purl.obolibrary.org/obo/GO_0017111 ribonucleoside triphosphate phosphatase activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient. http://purl.obolibrary.org/obo/GO_0017076 purine nucleotide binding http://purl.obolibrary.org/obo/GO_0000166 nucleotide binding Binding to a purine nucleotide, a compound consisting of a purine nucleoside esterified with (ortho)phosphate. http://purl.obolibrary.org/obo/GO_0017111 ribonucleoside triphosphate phosphatase activity http://purl.obolibrary.org/obo/GO_0016462 pyrophosphatase activity Catalysis of the reaction: a ribonucleoside triphosphate + H2O = a ribonucleoside diphosphate + H+ + phosphate. http://purl.obolibrary.org/obo/GO_0017157 regulation of exocytosis http://purl.obolibrary.org/obo/GO_0060627 regulation of vesicle-mediated transport Any process that modulates the frequency, rate or extent of exocytosis. http://purl.obolibrary.org/obo/GO_0019221 cytokine-mediated signaling pathway http://purl.obolibrary.org/obo/GO_0007166 cell surface receptor signaling pathway The series of molecular signals initiated by the binding of a cytokine to a receptor on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription. http://purl.obolibrary.org/obo/GO_0019236 response to pheromone http://purl.obolibrary.org/obo/GO_0042221 response to chemical Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pheromone stimulus. http://purl.obolibrary.org/obo/GO_0019724 B cell mediated immunity http://purl.obolibrary.org/obo/GO_0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains Any process involved with the carrying out of an immune response by a B cell, through, for instance, the production of antibodies or cytokines, or antigen presentation to T cells. http://purl.obolibrary.org/obo/GO_0019730 antimicrobial humoral response http://purl.obolibrary.org/obo/GO_0140546 defense response to symbiont An immune response against microbes mediated through a body fluid. Examples of this process are seen in the antimicrobial humoral response of Drosophila melanogaster and Mus musculus. http://purl.obolibrary.org/obo/GO_0019865 immunoglobulin binding http://purl.obolibrary.org/obo/GO_0044877 protein-containing complex binding Binding to an immunoglobulin. http://purl.obolibrary.org/obo/GO_0019882 antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002376 immune system process The process in which an antigen-presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex. http://purl.obolibrary.org/obo/GO_0019883 antigen processing and presentation of endogenous antigen http://purl.obolibrary.org/obo/GO_0019882 antigen processing and presentation The process in which an antigen-presenting cell expresses antigen (peptide or lipid) of endogenous origin on its cell surface in association with an MHC protein complex. http://purl.obolibrary.org/obo/GO_0019884 antigen processing and presentation of exogenous antigen http://purl.obolibrary.org/obo/GO_0019882 antigen processing and presentation The process in which an antigen-presenting cell expresses antigen (peptide or lipid) of exogenous origin on its cell surface in association with an MHC protein complex. http://purl.obolibrary.org/obo/GO_0019953 sexual reproduction http://purl.obolibrary.org/obo/GO_0022414 reproductive process A type of reproduction that combines the genetic material of two gametes (such as a sperm or egg cell or fungal spores). The gametes have an haploid genome (with a single set of chromosomes, the product of a meiotic division) and combines with one another to produce a zygote (diploid). http://purl.obolibrary.org/obo/GO_0019955 cytokine binding http://purl.obolibrary.org/obo/GO_0005515 protein binding Binding to a cytokine, any of a group of proteins that function to control the survival, growth and differentiation of tissues and cells, and which have autocrine and paracrine activity. http://purl.obolibrary.org/obo/GO_0021915 neural tube development http://purl.obolibrary.org/obo/GO_0060429 epithelium development The process whose specific outcome is the progression of the neural tube over time, from its formation to the mature structure. The mature structure of the neural tube exists when the tube has been segmented into the forebrain, midbrain, hindbrain and spinal cord regions. In addition neural crest has budded away from the epithelium. http://purl.obolibrary.org/obo/GO_0022402 cell cycle process http://purl.obolibrary.org/obo/GO_0009987 cellular process The cellular process that ensures successive accurate and complete genome replication and chromosome segregation. http://purl.obolibrary.org/obo/GO_0022403 cell cycle phase http://purl.obolibrary.org/obo/GO_0044848 biological phase One of the distinct periods or stages into which the cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events. http://purl.obolibrary.org/obo/GO_0022405 hair cycle process http://purl.obolibrary.org/obo/GO_0022404 molting cycle process A multicellular organismal process involved in the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair; one of the collection or mass of filaments growing from the skin of an animal, and forming a covering for a part of the head or for any part or the whole of the body. http://purl.obolibrary.org/obo/GO_0022412 cellular process involved in reproduction in multicellular organism http://purl.obolibrary.org/obo/GO_0009987 cellular process A process, occurring at the cellular level, that is involved in the reproductive function of a multicellular organism. http://purl.obolibrary.org/obo/GO_0022413 reproductive process in single-celled organism http://purl.obolibrary.org/obo/GO_0022414 reproductive process A process, occurring at the cellular level, that is involved in the reproductive function of a single-celled organism. http://purl.obolibrary.org/obo/GO_0022414 reproductive process http://purl.obolibrary.org/obo/GO_0008150 biological_process A biological process that directly contributes to the process of producing new individuals by one or two organisms. The new individuals inherit some proportion of their genetic material from the parent or parents. http://purl.obolibrary.org/obo/GO_0022600 digestive system process http://purl.obolibrary.org/obo/GO_0003008 system process A physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism. http://purl.obolibrary.org/obo/GO_0022602 ovulation cycle process http://purl.obolibrary.org/obo/GO_0022414 reproductive process A process involved in the sexual cycle seen in females, often with physiologic changes in the endometrium that recur at regular intervals during the reproductive years. http://purl.obolibrary.org/obo/GO_0022603 regulation of anatomical structure morphogenesis http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of anatomical structure morphogenesis. http://purl.obolibrary.org/obo/GO_0022607 cellular component assembly http://purl.obolibrary.org/obo/GO_0016043 cellular component organization The aggregation, arrangement and bonding together of a cellular component. http://purl.obolibrary.org/obo/GO_0022618 protein-RNA complex assembly http://purl.obolibrary.org/obo/GO_0071826 protein-RNA complex organization The aggregation, arrangement and bonding together of proteins and RNA molecules to form a ribonucleoprotein complex. http://purl.obolibrary.org/obo/GO_0023051 regulation of signaling http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process Any process that modulates the frequency, rate or extent of a signaling process. http://purl.obolibrary.org/obo/GO_0023056 positive regulation of signaling http://purl.obolibrary.org/obo/GO_0048518 positive regulation of biological process Any process that activates, maintains or increases the frequency, rate or extent of a signaling process. http://purl.obolibrary.org/obo/GO_0023057 negative regulation of signaling http://purl.obolibrary.org/obo/GO_0048519 negative regulation of biological process Any process that stops, prevents, or reduces the frequency, rate or extent of a signaling process. http://purl.obolibrary.org/obo/GO_0030001 metal ion transport http://purl.obolibrary.org/obo/GO_0006812 monoatomic cation transport The directed movement of metal ions, any metal ion with an electric charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0030010 establishment of cell polarity http://purl.obolibrary.org/obo/GO_0007163 establishment or maintenance of cell polarity The specification and formation of anisotropic intracellular organization or cell growth patterns. http://purl.obolibrary.org/obo/GO_0030097 hemopoiesis http://purl.obolibrary.org/obo/GO_0048468 cell development The process whose specific outcome is the progression of the myeloid and lymphoid derived organ/tissue systems of the blood and other parts of the body over time, from formation to the mature structure. The site of hemopoiesis is variable during development, but occurs primarily in bone marrow or kidney in many adult vertebrates. http://purl.obolibrary.org/obo/GO_0030098 lymphocyte differentiation http://purl.obolibrary.org/obo/GO_1903131 mononuclear cell differentiation The process in which a relatively unspecialized precursor cell acquires specialized features of a lymphocyte. A lymphocyte is a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin. http://purl.obolibrary.org/obo/GO_0030099 myeloid cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte, megakaryocyte, thrombocyte, or erythrocyte lineages. http://purl.obolibrary.org/obo/GO_0030101 natural killer cell activation http://purl.obolibrary.org/obo/GO_0046649 lymphocyte activation The change in morphology and behavior of a natural killer cell in response to a cytokine, chemokine, cellular ligand, or soluble factor. http://purl.obolibrary.org/obo/GO_0030103 vasopressin secretion http://purl.obolibrary.org/obo/GO_0030072 peptide hormone secretion The regulated release of vasopressin from secretory granules into the blood. http://purl.obolibrary.org/obo/GO_0030141 secretory granule http://purl.obolibrary.org/obo/GO_0099503 secretory vesicle A small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. Secretory granules move towards the periphery of the cell and upon stimulation, their membranes fuse with the cell membrane, and their protein load is exteriorized. Processing of the contained protein may take place in secretory granules. http://purl.obolibrary.org/obo/GO_0030154 cell differentiation http://purl.obolibrary.org/obo/GO_0048869 cellular developmental process The cellular developmental process in which a relatively unspecialized cell, e.g. embryonic or regenerative cell, acquires specialized structural and/or functional features that characterize a specific cell. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. http://purl.obolibrary.org/obo/GO_0030155 regulation of cell adhesion http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of attachment of a cell to another cell or to the extracellular matrix. http://purl.obolibrary.org/obo/GO_0030182 neuron differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a neuron. http://purl.obolibrary.org/obo/GO_0030183 B cell differentiation http://purl.obolibrary.org/obo/GO_0042113 B cell activation The process in which a precursor cell type acquires the specialized features of a B cell. A B cell is a lymphocyte of B lineage with the phenotype CD19-positive and capable of B cell mediated immunity. http://purl.obolibrary.org/obo/GO_0030194 positive regulation of blood coagulation http://purl.obolibrary.org/obo/GO_0030193 regulation of blood coagulation Any process that activates or increases the frequency, rate or extent of blood coagulation. http://purl.obolibrary.org/obo/GO_0030203 glycosaminoglycan metabolic process http://purl.obolibrary.org/obo/GO_0006022 aminoglycan metabolic process The chemical reactions and pathways involving glycosaminoglycans, any of a group of linear polysaccharides composed of repeating disaccharide units. http://purl.obolibrary.org/obo/GO_0030216 keratinocyte differentiation http://purl.obolibrary.org/obo/GO_0009913 epidermal cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a keratinocyte. http://purl.obolibrary.org/obo/GO_0030217 T cell differentiation http://purl.obolibrary.org/obo/GO_0042110 T cell activation The process in which a precursor cell type acquires characteristics of a more mature T-cell. A T cell is a type of lymphocyte whose definin characteristic is the expression of a T cell receptor complex. http://purl.obolibrary.org/obo/GO_0030247 polysaccharide binding http://purl.obolibrary.org/obo/GO_0030246 carbohydrate binding Binding to a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically. http://purl.obolibrary.org/obo/GO_0030261 chromosome condensation http://purl.obolibrary.org/obo/GO_0051276 chromosome organization The progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells. http://purl.obolibrary.org/obo/GO_0030334 regulation of cell migration http://purl.obolibrary.org/obo/GO_2000145 regulation of cell motility Any process that modulates the frequency, rate or extent of cell migration. http://purl.obolibrary.org/obo/GO_0030335 positive regulation of cell migration http://purl.obolibrary.org/obo/GO_2000147 positive regulation of cell motility Any process that activates or increases the frequency, rate or extent of cell migration. http://purl.obolibrary.org/obo/GO_0030336 negative regulation of cell migration http://purl.obolibrary.org/obo/GO_2000146 negative regulation of cell motility Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration. http://purl.obolibrary.org/obo/GO_0030473 nuclear migration along microtubule http://purl.obolibrary.org/obo/GO_0072384 organelle transport along microtubule The directed movement of the nucleus along microtubules within the cell, mediated by motor proteins. http://purl.obolibrary.org/obo/GO_0030554 adenyl nucleotide binding http://purl.obolibrary.org/obo/GO_0017076 purine nucleotide binding Binding to an adenyl nucleotide, an adenosine esterified with (ortho)phosphate. http://purl.obolibrary.org/obo/GO_0030595 leukocyte chemotaxis http://purl.obolibrary.org/obo/GO_0050900 leukocyte migration The movement of a leukocyte in response to an external stimulus. http://purl.obolibrary.org/obo/GO_0030667 secretory granule membrane http://purl.obolibrary.org/obo/GO_0030659 cytoplasmic vesicle membrane The lipid bilayer surrounding a secretory granule. http://purl.obolibrary.org/obo/GO_0030855 epithelial cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell, any of the cells making up an epithelium. http://purl.obolibrary.org/obo/GO_0030857 negative regulation of epithelial cell differentiation http://purl.obolibrary.org/obo/GO_0030856 regulation of epithelial cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of epithelial cell differentiation. http://purl.obolibrary.org/obo/GO_0030879 mammary gland development http://purl.obolibrary.org/obo/GO_0048732 gland development The process whose specific outcome is the progression of the mammary gland over time, from its formation to the mature structure. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk. Its development starts with the formation of the mammary line and ends as the mature gland cycles between nursing and weaning stages. http://purl.obolibrary.org/obo/GO_0030952 establishment or maintenance of cytoskeleton polarity http://purl.obolibrary.org/obo/GO_0007010 cytoskeleton organization Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures. http://purl.obolibrary.org/obo/GO_0031018 endocrine pancreas development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the endocrine pancreas over time, from its formation to the mature structure. The endocrine pancreas is made up of islet cells that produce insulin, glucagon and somatostatin. http://purl.obolibrary.org/obo/GO_0031128 developmental induction http://purl.obolibrary.org/obo/GO_0032502 developmental process A developmental process involving two tissues in which one tissue (the inducer) produces a signal that directs cell fate commitment of cells in the second tissue (the responder). http://purl.obolibrary.org/obo/GO_0031175 neuron projection development http://purl.obolibrary.org/obo/GO_0120036 plasma membrane bounded cell projection organization The process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites). http://purl.obolibrary.org/obo/GO_0031252 cell leading edge http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure The area of a motile cell closest to the direction of movement. http://purl.obolibrary.org/obo/GO_0031333 negative regulation of protein-containing complex assembly http://purl.obolibrary.org/obo/GO_0051129 negative regulation of cellular component organization Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex assembly. http://purl.obolibrary.org/obo/GO_0031334 positive regulation of protein-containing complex assembly http://purl.obolibrary.org/obo/GO_0051130 positive regulation of cellular component organization Any process that activates or increases the frequency, rate or extent of protein complex assembly. http://purl.obolibrary.org/obo/GO_0031341 regulation of cell killing http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of cell killing, the process in which a cell brings about the death of another cell, either in the same or a different organism. http://purl.obolibrary.org/obo/GO_0031342 negative regulation of cell killing http://purl.obolibrary.org/obo/GO_0031341 regulation of cell killing Any process that stops, prevents, or reduces the frequency, rate or extent of cell killing. http://purl.obolibrary.org/obo/GO_0031343 positive regulation of cell killing http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the frequency, rate or extent of cell killing. http://purl.obolibrary.org/obo/GO_0031348 negative regulation of defense response http://purl.obolibrary.org/obo/GO_0031347 regulation of defense response Any process that stops, prevents, or reduces the frequency, rate or extent of a defense response. http://purl.obolibrary.org/obo/GO_0031349 positive regulation of defense response http://purl.obolibrary.org/obo/GO_0031347 regulation of defense response Any process that activates or increases the frequency, rate or extent of a defense response. http://purl.obolibrary.org/obo/GO_0031410 cytoplasmic vesicle http://purl.obolibrary.org/obo/GO_0097708 intracellular vesicle A vesicle found in the cytoplasm of a cell. http://purl.obolibrary.org/obo/GO_0031981 nuclear lumen http://purl.obolibrary.org/obo/GO_0070013 intracellular organelle lumen The volume enclosed by the nuclear inner membrane. http://purl.obolibrary.org/obo/GO_0032091 negative regulation of protein binding http://purl.obolibrary.org/obo/GO_0051100 negative regulation of binding Any process that stops, prevents, or reduces the frequency, rate or extent of protein binding. http://purl.obolibrary.org/obo/GO_0032101 regulation of response to external stimulus http://purl.obolibrary.org/obo/GO_0048583 regulation of response to stimulus Any process that modulates the frequency, rate or extent of a response to an external stimulus. http://purl.obolibrary.org/obo/GO_0032103 positive regulation of response to external stimulus http://purl.obolibrary.org/obo/GO_0048584 positive regulation of response to stimulus Any process that activates, maintains or increases the rate of a response to an external stimulus. http://purl.obolibrary.org/obo/GO_0032271 regulation of protein polymerization http://purl.obolibrary.org/obo/GO_0043254 regulation of protein-containing complex assembly Any process that modulates the frequency, rate or extent of the process of creating protein polymers. http://purl.obolibrary.org/obo/GO_0032432 actin filament bundle http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure An assembly of actin filaments that are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness. http://purl.obolibrary.org/obo/GO_0032501 multicellular organismal process http://purl.obolibrary.org/obo/GO_0008150 biological_process Any biological process, occurring at the level of a multicellular organism, pertinent to its function. http://purl.obolibrary.org/obo/GO_0032502 developmental process http://purl.obolibrary.org/obo/GO_0008150 biological_process A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition. http://purl.obolibrary.org/obo/GO_0032774 RNA biosynthetic process http://purl.obolibrary.org/obo/GO_0016070 RNA metabolic process The chemical reactions and pathways resulting in the formation of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. Includes polymerization of ribonucleotide monomers. Refers not only to transcription but also to e.g. viral RNA replication. http://purl.obolibrary.org/obo/GO_0032781 positive regulation of ATP-dependent activity http://purl.obolibrary.org/obo/GO_0043462 regulation of ATP-dependent activity Any process that activates or increases the rate of an ATP-dependent activity. http://purl.obolibrary.org/obo/GO_0032940 secretion by cell http://purl.obolibrary.org/obo/GO_0046903 secretion The controlled release of a substance by a cell. http://purl.obolibrary.org/obo/GO_0032984 protein-containing complex disassembly http://purl.obolibrary.org/obo/GO_0043933 protein-containing complex organization The disaggregation of a protein-containing macromolecular complex into its constituent components. http://purl.obolibrary.org/obo/GO_0032988 protein-RNA complex disassembly http://purl.obolibrary.org/obo/GO_0071826 protein-RNA complex organization The disaggregation of a protein-RNA complex into its constituent components. http://purl.obolibrary.org/obo/GO_0032989 cellular anatomical entity morphogenesis http://purl.obolibrary.org/obo/GO_0016043 cellular component organization The process in which a cellular entity is generated and organized. A cellular entity has granularity above the level of a protein complex but below that of an anatomical system. http://purl.obolibrary.org/obo/GO_0032991 protein-containing complex http://purl.obolibrary.org/obo/GO_0005575 cellular_component A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together. http://purl.obolibrary.org/obo/GO_0033028 myeloid cell apoptotic process http://purl.obolibrary.org/obo/GO_0006915 apoptotic process Any apoptotic process in a myeloid cell, a cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroid lineage. http://purl.obolibrary.org/obo/GO_0033043 regulation of organelle organization http://purl.obolibrary.org/obo/GO_0051128 regulation of cellular component organization Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle. http://purl.obolibrary.org/obo/GO_0033293 monocarboxylic acid binding http://purl.obolibrary.org/obo/GO_0031406 carboxylic acid binding Binding to a monocarboxylic acid, any organic acid containing one carboxyl (COOH) group or anion (COO-). http://purl.obolibrary.org/obo/GO_0033363 secretory granule organization http://purl.obolibrary.org/obo/GO_0016050 vesicle organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule. A secretory granule is a small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. http://purl.obolibrary.org/obo/GO_0033554 cellular response to stress http://purl.obolibrary.org/obo/GO_0006950 response to stress Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). http://purl.obolibrary.org/obo/GO_0034599 cellular response to oxidative stress http://purl.obolibrary.org/obo/GO_0062197 cellular response to chemical stress Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals. http://purl.obolibrary.org/obo/GO_0034706 sodium channel complex http://purl.obolibrary.org/obo/GO_0034703 cation channel complex An ion channel complex through which sodium ions pass. http://purl.obolibrary.org/obo/GO_0034755 iron ion transmembrane transport http://purl.obolibrary.org/obo/GO_0098655 monoatomic cation transmembrane transport A process in which an iron ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0035050 embryonic heart tube development http://purl.obolibrary.org/obo/GO_0060429 epithelium development The process whose specific outcome is the progression of the embryonic heart tube over time, from its formation to the mature structure. The heart tube forms as the heart rudiment from the heart field. http://purl.obolibrary.org/obo/GO_0035051 cardiocyte differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell that will form part of the cardiac organ of an individual. http://purl.obolibrary.org/obo/GO_0035282 segmentation http://purl.obolibrary.org/obo/GO_0003002 regionalization The regionalization process that divides an organism or part of an organism into a series of semi-repetitive parts, or segments, often arranged along a longitudinal axis. http://purl.obolibrary.org/obo/GO_0035556 intracellular signal transduction http://purl.obolibrary.org/obo/GO_0007165 signal transduction The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell. http://purl.obolibrary.org/obo/GO_0035590 purinergic nucleotide receptor signaling pathway http://purl.obolibrary.org/obo/GO_0007166 cell surface receptor signaling pathway The series of molecular signals initiated by an extracellular purine nucleotide binding to its receptor, and ending with the regulation of a downstream cellular process, e.g. transcription. http://purl.obolibrary.org/obo/GO_0035850 epithelial cell differentiation involved in kidney development http://purl.obolibrary.org/obo/GO_0061005 cell differentiation involved in kidney development The process in which relatively unspecialized cells acquire specialized structural and/or functional features of an epithelial cell that characterize the cells of the kidney as it progresses from its formation to the mature state. http://purl.obolibrary.org/obo/GO_0035883 enteroendocrine cell differentiation http://purl.obolibrary.org/obo/GO_0030855 epithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of an enteroendocrine cell. Enteroendocrine cells are hormonally active epithelial cells in the gut that constitute the diffuse neuroendocrine system. http://purl.obolibrary.org/obo/GO_0035932 aldosterone secretion http://purl.obolibrary.org/obo/GO_0035931 mineralocorticoid secretion The regulated release of aldosterone into the circulatory system. Aldosterone is a pregnane-based steroid hormone produced by the outer-section (zona glomerulosa) of the adrenal cortex in the adrenal gland, and acts on the distal tubules and collecting ducts of the kidney to cause the conservation of sodium, secretion of potassium, increased water retention, and increased blood pressure. The overall effect of aldosterone is to increase reabsorption of ions and water in the kidney. http://purl.obolibrary.org/obo/GO_0035987 endodermal cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of an endoderm cell, a cell of the inner of the three germ layers of the embryo. http://purl.obolibrary.org/obo/GO_0035989 tendon development http://purl.obolibrary.org/obo/GO_0061448 connective tissue development The process whose specific outcome is the progression of a tendon over time, from its formation to the mature structure. A tendon is a fibrous, strong, connective tissue that connects muscle to bone or integument and is capable of withstanding tension. Tendons and muscles work together to exert a pulling force. http://purl.obolibrary.org/obo/GO_0036072 direct ossification http://purl.obolibrary.org/obo/GO_0001503 ossification The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance, that does not require the replacement of preexisting tissues. http://purl.obolibrary.org/obo/GO_0036075 replacement ossification http://purl.obolibrary.org/obo/GO_0001503 ossification Ossification that requires the replacement of a preexisting tissue prior to bone tissue formation. http://purl.obolibrary.org/obo/GO_0036093 germ cell proliferation http://purl.obolibrary.org/obo/GO_0008283 cell population proliferation The multiplication or reproduction of germ cells, reproductive cells in multicellular organisms, resulting in the expansion of a cell population. http://purl.obolibrary.org/obo/GO_0036094 small molecule binding http://purl.obolibrary.org/obo/GO_0005488 binding Binding to a small molecule, any low molecular weight, monomeric, non-encoded molecule. http://purl.obolibrary.org/obo/GO_0036293 response to decreased oxygen levels http://purl.obolibrary.org/obo/GO_0070482 response to oxygen levels Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting a decline in the level of oxygen. http://purl.obolibrary.org/obo/GO_0036303 lymph vessel morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structures of lymph vessels are generated and organized. The lymph vessel is the vasculature carrying lymph. http://purl.obolibrary.org/obo/GO_0036336 dendritic cell migration http://purl.obolibrary.org/obo/GO_0071674 mononuclear cell migration The movement of a dendritic cell within or between different tissues and organs of the body. http://purl.obolibrary.org/obo/GO_0038023 signaling receptor activity http://purl.obolibrary.org/obo/GO_0060089 molecular transducer activity Receiving a signal and transmitting it in the cell to initiate a change in cell activity. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response. http://purl.obolibrary.org/obo/GO_0040007 growth http://purl.obolibrary.org/obo/GO_0008150 biological_process The increase in size or mass of an entire organism, a part of an organism or a cell. http://purl.obolibrary.org/obo/GO_0040008 regulation of growth http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process Any process that modulates the frequency, rate or extent of the growth of all or part of an organism so that it occurs at its proper speed, either globally or in a specific part of the organism's development. http://purl.obolibrary.org/obo/GO_0042060 wound healing http://purl.obolibrary.org/obo/GO_0009611 response to wounding The series of events that restore integrity to a damaged tissue, following an injury. http://purl.obolibrary.org/obo/GO_0042074 cell migration involved in gastrulation http://purl.obolibrary.org/obo/GO_0001667 ameboidal-type cell migration The migration of individual cells within the blastocyst to help establish the multi-layered body plan of the organism (gastrulation). For example, the migration of cells from the surface to the interior of the embryo (ingression). http://purl.obolibrary.org/obo/GO_0042088 T-helper 1 type immune response http://purl.obolibrary.org/obo/GO_0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains An immune response which is associated with resistance to intracellular bacteria, fungi, and protozoa, and pathological conditions such as arthritis, and which is typically orchestrated by the production of particular cytokines by T-helper 1 cells, most notably interferon-gamma, IL-2, and lymphotoxin. http://purl.obolibrary.org/obo/GO_0042092 type 2 immune response http://purl.obolibrary.org/obo/GO_0006955 immune response An immune response which is associated with resistance to extracellular organisms such as helminths and pathological conditions such as allergy, which is orchestrated by the production of particular cytokines, most notably IL-4, IL-5, IL-10, and IL-13, by any of a variety of cell types including T-helper 2 cells, eosinophils, basophils, mast cells, and nuocytes, resulting in enhanced production of certain antibody isotypes and other effects. http://purl.obolibrary.org/obo/GO_0042093 T-helper cell differentiation http://purl.obolibrary.org/obo/GO_0043367 CD4-positive, alpha-beta T cell differentiation The process in which a relatively unspecialized thymocyte acquires specialized features of a T-helper cell. http://purl.obolibrary.org/obo/GO_0042098 T cell proliferation http://purl.obolibrary.org/obo/GO_0046651 lymphocyte proliferation The expansion of a T cell population by cell division. Follows T cell activation. http://purl.obolibrary.org/obo/GO_0042100 B cell proliferation http://purl.obolibrary.org/obo/GO_0046651 lymphocyte proliferation The expansion of a B cell population by cell division. Follows B cell activation. http://purl.obolibrary.org/obo/GO_0042110 T cell activation http://purl.obolibrary.org/obo/GO_0046649 lymphocyte activation The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. http://purl.obolibrary.org/obo/GO_0042113 B cell activation http://purl.obolibrary.org/obo/GO_0046649 lymphocyte activation The change in morphology and behavior of a mature or immature B cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. http://purl.obolibrary.org/obo/GO_0042116 macrophage activation http://purl.obolibrary.org/obo/GO_0002274 myeloid leukocyte activation A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. http://purl.obolibrary.org/obo/GO_0042117 monocyte activation http://purl.obolibrary.org/obo/GO_0002274 myeloid leukocyte activation The change in morphology and behavior of a monocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. http://purl.obolibrary.org/obo/GO_0042118 endothelial cell activation http://purl.obolibrary.org/obo/GO_0001775 cell activation The change in morphology and behavior of an endothelial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. http://purl.obolibrary.org/obo/GO_0042119 neutrophil activation http://purl.obolibrary.org/obo/GO_0036230 granulocyte activation The change in morphology and behavior of a neutrophil resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. http://purl.obolibrary.org/obo/GO_0042127 regulation of cell population proliferation http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of cell proliferation. http://purl.obolibrary.org/obo/GO_0042159 lipoprotein catabolic process http://purl.obolibrary.org/obo/GO_0042157 lipoprotein metabolic process The chemical reactions and pathways resulting in the breakdown of any conjugated, water-soluble protein in which the covalently attached nonprotein group consists of a lipid or lipids. http://purl.obolibrary.org/obo/GO_0042221 response to chemical http://purl.obolibrary.org/obo/GO_0050896 response to stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus. http://purl.obolibrary.org/obo/GO_0042254 ribosome biogenesis http://purl.obolibrary.org/obo/GO_0022613 ribonucleoprotein complex biogenesis A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits; includes transport to the sites of protein synthesis. http://purl.obolibrary.org/obo/GO_0042255 ribosome assembly http://purl.obolibrary.org/obo/GO_0140694 membraneless organelle assembly The aggregation, arrangement and bonding together of the mature ribosome and of its subunits. http://purl.obolibrary.org/obo/GO_0042267 natural killer cell mediated cytotoxicity http://purl.obolibrary.org/obo/GO_0002228 natural killer cell mediated immunity The directed killing of a target cell by a natural killer cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors. http://purl.obolibrary.org/obo/GO_0042269 regulation of natural killer cell mediated cytotoxicity http://purl.obolibrary.org/obo/GO_0002715 regulation of natural killer cell mediated immunity Any process that modulates the frequency, rate, or extent of natural killer cell mediated cytotoxicity. http://purl.obolibrary.org/obo/GO_0042277 peptide binding http://purl.obolibrary.org/obo/GO_0005488 binding Binding to a peptide, an organic compound comprising two or more amino acids linked by peptide bonds. http://purl.obolibrary.org/obo/GO_0042330 taxis http://purl.obolibrary.org/obo/GO_0040011 locomotion The directed movement of a motile cell or organism in response to an external stimulus. http://purl.obolibrary.org/obo/GO_0042391 regulation of membrane potential http://purl.obolibrary.org/obo/GO_0065008 regulation of biological quality Any process that modulates the establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane. http://purl.obolibrary.org/obo/GO_0042401 biogenic amine biosynthetic process http://purl.obolibrary.org/obo/GO_0009309 amine biosynthetic process The chemical reactions and pathways occurring at the level of individual cells resulting in the formation of any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters. http://purl.obolibrary.org/obo/GO_0042402 biogenic amine catabolic process http://purl.obolibrary.org/obo/GO_0009310 amine catabolic process The chemical reactions and pathways occurring at the level of individual cells resulting in the breakdown of biogenic amines, any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters. http://purl.obolibrary.org/obo/GO_0042419 epinephrine catabolic process http://purl.obolibrary.org/obo/GO_0042424 catecholamine catabolic process The chemical reactions and pathways resulting in the breakdown of epinephrine, a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine. http://purl.obolibrary.org/obo/GO_0042472 inner ear morphogenesis http://purl.obolibrary.org/obo/GO_0048598 embryonic morphogenesis The process in which the anatomical structures of the inner ear are generated and organized. The inner ear is the structure in vertebrates that contains the organs of balance and hearing. It consists of soft hollow sensory structures (the membranous labyrinth) containing fluid (endolymph) surrounded by fluid (perilymph) and encased in a bony cavity (the bony labyrinth). It consists of two chambers, the sacculus and utriculus, from which arise the cochlea and semicircular canals respectively. http://purl.obolibrary.org/obo/GO_0042492 gamma-delta T cell differentiation http://purl.obolibrary.org/obo/GO_0046629 gamma-delta T cell activation The process in which a relatively unspecialized hemopoietic cell acquires specialized features of a gamma-delta T cell. A gamma-delta T cell is a T cell that expresses a gamma-delta T cell receptor complex. http://purl.obolibrary.org/obo/GO_0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I http://purl.obolibrary.org/obo/GO_0002478 antigen processing and presentation of exogenous peptide antigen The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class I protein complex. The peptide antigen is typically, but not always, processed from a whole protein. Class I here refers to classical class I molecules. http://purl.obolibrary.org/obo/GO_0042592 homeostatic process http://purl.obolibrary.org/obo/GO_0008150 biological_process Any biological process involved in the maintenance of an internal steady state. Homeostasis allows cells and organisms to maintain stable internal conditions despite varying external conditions. http://purl.obolibrary.org/obo/GO_0042593 glucose homeostasis http://purl.obolibrary.org/obo/GO_0033500 carbohydrate homeostasis Any process involved in the maintenance of an internal steady state of glucose within an organism or cell. http://purl.obolibrary.org/obo/GO_0042641 actomyosin http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure Any complex of actin, myosin, and accessory proteins. http://purl.obolibrary.org/obo/GO_0042645 mitochondrial nucleoid http://purl.obolibrary.org/obo/GO_0009295 nucleoid The region of a mitochondrion to which the DNA is confined. http://purl.obolibrary.org/obo/GO_0042981 regulation of apoptotic process http://purl.obolibrary.org/obo/GO_0043067 regulation of programmed cell death Any process that modulates the occurrence or rate of cell death by apoptotic process. http://purl.obolibrary.org/obo/GO_0042995 cell projection http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure A prolongation or process extending from a cell, e.g. a flagellum or axon. http://purl.obolibrary.org/obo/GO_0043009 chordate embryonic development http://purl.obolibrary.org/obo/GO_0009792 embryo development ending in birth or egg hatching The process whose specific outcome is the progression of the embryo over time, from zygote formation through a stage including a notochord and neural tube until birth or egg hatching. http://purl.obolibrary.org/obo/GO_0043010 camera-type eye development http://purl.obolibrary.org/obo/GO_0001654 eye development The process whose specific outcome is the progression of the camera-type eye over time, from its formation to the mature structure. The camera-type eye is an organ of sight that receives light through an aperture and focuses it through a lens, projecting it on a photoreceptor field. http://purl.obolibrary.org/obo/GO_0043011 myeloid dendritic cell differentiation http://purl.obolibrary.org/obo/GO_0097028 dendritic cell differentiation The process in which a monocyte acquires the specialized features of a dendritic cell, an immunocompetent cell of the lymphoid and hemopoietic systems and skin. http://purl.obolibrary.org/obo/GO_0043029 T cell homeostasis http://purl.obolibrary.org/obo/GO_0002260 lymphocyte homeostasis The process of regulating the proliferation and elimination of T cells such that the total number of T cells within a whole or part of an organism is stable over time in the absence of an outside stimulus. http://purl.obolibrary.org/obo/GO_0043043 peptide biosynthetic process http://purl.obolibrary.org/obo/GO_0009058 biosynthetic process The chemical reactions and pathways resulting in the formation of peptides, compounds of 2 or more (but usually less than 100) amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another. This may include the translation of a precursor protein and its subsequent processing into a functional peptide. http://purl.obolibrary.org/obo/GO_0043073 germ cell nucleus http://purl.obolibrary.org/obo/GO_0005634 nucleus The nucleus of a germ cell, a reproductive cell in multicellular organisms. http://purl.obolibrary.org/obo/GO_0043083 synaptic cleft http://purl.obolibrary.org/obo/GO_0005576 extracellular region The narrow gap that separates the presynaptic and postsynaptic membranes, into which neurotransmitter is released. http://purl.obolibrary.org/obo/GO_0043114 regulation of vascular permeability http://purl.obolibrary.org/obo/GO_0065008 regulation of biological quality Any process that modulates the extent to which blood vessels can be pervaded by fluid. http://purl.obolibrary.org/obo/GO_0043168 anion binding http://purl.obolibrary.org/obo/GO_0043167 ion binding Binding to an anion, a charged atom or group of atoms with a net negative charge. http://purl.obolibrary.org/obo/GO_0043171 peptide catabolic process http://purl.obolibrary.org/obo/GO_0009056 catabolic process The chemical reactions and pathways resulting in the breakdown of peptides, compounds of 2 or more (but usually less than 100) amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another. http://purl.obolibrary.org/obo/GO_0043178 alcohol binding http://purl.obolibrary.org/obo/GO_0036094 small molecule binding Binding to an alcohol, any of a class of alkyl compounds containing a hydroxyl group. http://purl.obolibrary.org/obo/GO_0043207 response to external biotic stimulus http://purl.obolibrary.org/obo/GO_0009607 response to biotic stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external biotic stimulus, an external stimulus caused by, or produced by living things. http://purl.obolibrary.org/obo/GO_0043226 organelle http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane. http://purl.obolibrary.org/obo/GO_0043232 intracellular membraneless organelle http://purl.obolibrary.org/obo/GO_0043228 membraneless organelle Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes. http://purl.obolibrary.org/obo/GO_0043235 receptor complex http://purl.obolibrary.org/obo/GO_0032991 protein-containing complex Any protein complex that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function. http://purl.obolibrary.org/obo/GO_0043254 regulation of protein-containing complex assembly http://purl.obolibrary.org/obo/GO_0051128 regulation of cellular component organization Any process that modulates the frequency, rate or extent of protein complex assembly. http://purl.obolibrary.org/obo/GO_0043299 leukocyte degranulation http://purl.obolibrary.org/obo/GO_0045055 regulated exocytosis The regulated exocytosis of secretory granules by a leukocyte. http://purl.obolibrary.org/obo/GO_0043303 mast cell degranulation http://purl.obolibrary.org/obo/GO_0051656 establishment of organelle localization The regulated exocytosis of secretory granules containing preformed mediators such as histamine, serotonin, and neutral proteases by a mast cell. http://purl.obolibrary.org/obo/GO_0043307 eosinophil activation http://purl.obolibrary.org/obo/GO_0036230 granulocyte activation The change in morphology and behavior of a eosinophil resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. http://purl.obolibrary.org/obo/GO_0043367 CD4-positive, alpha-beta T cell differentiation http://purl.obolibrary.org/obo/GO_0035710 CD4-positive, alpha-beta T cell activation The process in which a relatively unspecialized T cell acquires specialized features of a mature CD4-positive, alpha-beta T cell. http://purl.obolibrary.org/obo/GO_0043374 CD8-positive, alpha-beta T cell differentiation http://purl.obolibrary.org/obo/GO_0036037 CD8-positive, alpha-beta T cell activation The process in which a relatively unspecialized T cell acquires specialized features of a mature CD8-positive, alpha-beta T cell. http://purl.obolibrary.org/obo/GO_0043436 oxoacid metabolic process http://purl.obolibrary.org/obo/GO_0006082 organic acid metabolic process The chemical reactions and pathways involving any oxoacid; an oxoacid is a compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons). http://purl.obolibrary.org/obo/GO_0043467 regulation of generation of precursor metabolites and energy http://purl.obolibrary.org/obo/GO_0019222 regulation of metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of precursor metabolites, substances from which energy is derived, and the processes involved in the liberation of energy from these substances. http://purl.obolibrary.org/obo/GO_0043500 muscle adaptation http://purl.obolibrary.org/obo/GO_0003012 muscle system process A process in which muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities. http://purl.obolibrary.org/obo/GO_0043531 ADP binding http://purl.obolibrary.org/obo/GO_0043168 anion binding Binding to ADP, adenosine 5'-diphosphate. http://purl.obolibrary.org/obo/GO_0043534 blood vessel endothelial cell migration http://purl.obolibrary.org/obo/GO_0043542 endothelial cell migration The orderly movement of an endothelial cell into the extracellular matrix in order to form new blood vessels during angiogenesis. http://purl.obolibrary.org/obo/GO_0043933 protein-containing complex organization http://purl.obolibrary.org/obo/GO_0016043 cellular component organization Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein complex. http://purl.obolibrary.org/obo/GO_0044065 regulation of respiratory system process http://purl.obolibrary.org/obo/GO_0043576 regulation of respiratory gaseous exchange Any process that modulates the frequency, rate or extent of a respiratory system process, an organ system process carried out by any of the organs or tissues of the respiratory system. http://purl.obolibrary.org/obo/GO_0044272 sulfur compound biosynthetic process http://purl.obolibrary.org/obo/GO_0009058 biosynthetic process The chemical reactions and pathways resulting in the formation of compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione. http://purl.obolibrary.org/obo/GO_0044273 sulfur compound catabolic process http://purl.obolibrary.org/obo/GO_0009056 catabolic process The chemical reactions and pathways resulting in the breakdown of compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione. http://purl.obolibrary.org/obo/GO_0044282 small molecule catabolic process http://purl.obolibrary.org/obo/GO_0009056 catabolic process The chemical reactions and pathways resulting in the breakdown of small molecules, any low molecular weight, monomeric, non-encoded molecule. http://purl.obolibrary.org/obo/GO_0044283 small molecule biosynthetic process http://purl.obolibrary.org/obo/GO_0009058 biosynthetic process The chemical reactions and pathways resulting in the formation of small molecules, any low molecular weight, monomeric, non-encoded molecule. http://purl.obolibrary.org/obo/GO_0044703 multi-organism reproductive process http://purl.obolibrary.org/obo/GO_0022414 reproductive process A biological process that directly contributes to the process of producing new individuals, involving another organism. http://purl.obolibrary.org/obo/GO_0044848 biological phase http://purl.obolibrary.org/obo/GO_0008150 biological_process A distinct period or stage in a biological process or cycle. http://purl.obolibrary.org/obo/GO_0045026 plasma membrane fusion http://purl.obolibrary.org/obo/GO_0061025 membrane fusion The joining of the lipid bilayer membrane that surround a cell with that of another cell, producing a single cell. http://purl.obolibrary.org/obo/GO_0045028 G protein-coupled purinergic nucleotide receptor activity http://purl.obolibrary.org/obo/GO_0004930 G protein-coupled receptor activity Combining with a purine nucleotide and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. http://purl.obolibrary.org/obo/GO_0045055 regulated exocytosis http://purl.obolibrary.org/obo/GO_0006887 exocytosis A process of exocytosis in which soluble proteins and other substances are initially stored in secretory vesicles for later release. It is found mainly in cells that are specialized for secreting products such as hormones, neurotransmitters, or digestive enzymes rapidly on demand. http://purl.obolibrary.org/obo/GO_0045063 T-helper 1 cell differentiation http://purl.obolibrary.org/obo/GO_0042093 T-helper cell differentiation The process in which a relatively unspecialized T cell acquires the specialized features of a T-helper 1 (Th1) cell. A Th1 cell is a CD4-positive, alpha-beta T cell that has the phenotype T-bet-positive and produces interferon-gamma. http://purl.obolibrary.org/obo/GO_0045064 T-helper 2 cell differentiation http://purl.obolibrary.org/obo/GO_0042093 T-helper cell differentiation The process in which a relatively unspecialized T cell acquires specialized features of a T-helper 2 (Th2) cell. A Th2 cell is a CD4-positive, alpha-beta T cell that has the phenotype GATA-3-positive and produces interleukin-4. http://purl.obolibrary.org/obo/GO_0045065 cytotoxic T cell differentiation http://purl.obolibrary.org/obo/GO_0030217 T cell differentiation The process in which a relatively unspecialized T cell acquires specialized features of a cytotoxic T cell. http://purl.obolibrary.org/obo/GO_0045066 regulatory T cell differentiation http://purl.obolibrary.org/obo/GO_0030217 T cell differentiation The process in which a relatively unspecialized T cell acquires specialized features of a regulatory T cell. Regulatory T cells control or suppress immune responses through a variety of mechanisms and subsets include the CD4+CD25+ cell type as well as certain CD8+ cell types. http://purl.obolibrary.org/obo/GO_0045087 innate immune response http://purl.obolibrary.org/obo/GO_0140546 defense response to symbiont Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens. http://purl.obolibrary.org/obo/GO_0045088 regulation of innate immune response http://purl.obolibrary.org/obo/GO_0031347 regulation of defense response Any process that modulates the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection. http://purl.obolibrary.org/obo/GO_0045089 positive regulation of innate immune response http://purl.obolibrary.org/obo/GO_0050778 positive regulation of immune response Any process that activates or increases the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection. http://purl.obolibrary.org/obo/GO_0045120 pronucleus http://purl.obolibrary.org/obo/GO_0005634 nucleus The nucleus of either the ovum or the spermatozoon following fertilization. Thus, in the fertilized ovum, there are two pronuclei, one originating from the ovum, the other from the spermatozoon that brought about fertilization; they approach each other, but do not fuse until just before the first cleavage, when each pronucleus loses its membrane to release its contents. http://purl.obolibrary.org/obo/GO_0045165 cell fate commitment http://purl.obolibrary.org/obo/GO_0048869 cellular developmental process The cellular developmental process by which a cell establishes the intrinsic character of a cell or tissue region irreversibly committing it to a particular fate. http://purl.obolibrary.org/obo/GO_0045216 cell-cell junction organization http://purl.obolibrary.org/obo/GO_0034330 cell junction organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell-cell junction. A cell-cell junction is a specialized region of connection between two cells. http://purl.obolibrary.org/obo/GO_0045321 leukocyte activation http://purl.obolibrary.org/obo/GO_0002376 immune system process A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor. http://purl.obolibrary.org/obo/GO_0045446 endothelial cell differentiation http://purl.obolibrary.org/obo/GO_0030855 epithelial cell differentiation The process in which a mesodermal, bone marrow or neural crest cell acquires specialized features of an endothelial cell, a thin flattened cell. A layer of such cells lines the inside surfaces of body cavities, blood vessels, and lymph vessels, making up the endothelium. http://purl.obolibrary.org/obo/GO_0045575 basophil activation http://purl.obolibrary.org/obo/GO_0036230 granulocyte activation The change in morphology and behavior of a basophil resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the basophil has specifically bound via IgE bound to Fc-epsilonRI receptors. http://purl.obolibrary.org/obo/GO_0045576 mast cell activation http://purl.obolibrary.org/obo/GO_0002274 myeloid leukocyte activation The change in morphology and behavior of a mast cell resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the mast cell has specifically bound via IgE bound to Fc-epsilonRI receptors. http://purl.obolibrary.org/obo/GO_0045577 regulation of B cell differentiation http://purl.obolibrary.org/obo/GO_0050864 regulation of B cell activation Any process that modulates the frequency, rate or extent of B cell differentiation. http://purl.obolibrary.org/obo/GO_0045578 negative regulation of B cell differentiation http://purl.obolibrary.org/obo/GO_0050869 negative regulation of B cell activation Any process that stops, prevents, or reduces the frequency, rate or extent of B cell differentiation. http://purl.obolibrary.org/obo/GO_0045579 positive regulation of B cell differentiation http://purl.obolibrary.org/obo/GO_0050871 positive regulation of B cell activation Any process that activates or increases the frequency, rate or extent of B cell differentiation. http://purl.obolibrary.org/obo/GO_0045637 regulation of myeloid cell differentiation http://purl.obolibrary.org/obo/GO_1903706 regulation of hemopoiesis Any process that modulates the frequency, rate or extent of myeloid cell differentiation. http://purl.obolibrary.org/obo/GO_0045638 negative regulation of myeloid cell differentiation http://purl.obolibrary.org/obo/GO_0045637 regulation of myeloid cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of myeloid cell differentiation. http://purl.obolibrary.org/obo/GO_0045639 positive regulation of myeloid cell differentiation http://purl.obolibrary.org/obo/GO_0045597 positive regulation of cell differentiation Any process that activates or increases the frequency, rate or extent of myeloid cell differentiation. http://purl.obolibrary.org/obo/GO_0045730 respiratory burst http://purl.obolibrary.org/obo/GO_0008152 metabolic process A phase of elevated metabolic activity, during which oxygen consumption increases; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals. http://purl.obolibrary.org/obo/GO_0045744 negative regulation of G protein-coupled receptor signaling pathway http://purl.obolibrary.org/obo/GO_0008277 regulation of G protein-coupled receptor signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of G protein-coupled receptor signaling pathway. http://purl.obolibrary.org/obo/GO_0045786 negative regulation of cell cycle http://purl.obolibrary.org/obo/GO_0051726 regulation of cell cycle Any process that stops, prevents or reduces the rate or extent of progression through the cell cycle. http://purl.obolibrary.org/obo/GO_0045822 negative regulation of heart contraction http://purl.obolibrary.org/obo/GO_0008016 regulation of heart contraction Any process that stops, prevents, or reduces the frequency, rate or extent of heart contraction. http://purl.obolibrary.org/obo/GO_0045823 positive regulation of heart contraction http://purl.obolibrary.org/obo/GO_0008016 regulation of heart contraction Any process that activates or increases the frequency, rate or extent of heart contraction. http://purl.obolibrary.org/obo/GO_0045824 negative regulation of innate immune response http://purl.obolibrary.org/obo/GO_0032102 negative regulation of response to external stimulus Any process that stops, prevents, or reduces the frequency, rate or extent of the innate immune response. http://purl.obolibrary.org/obo/GO_0045839 negative regulation of mitotic nuclear division http://purl.obolibrary.org/obo/GO_0010948 negative regulation of cell cycle process Any process that stops, prevents or reduces the rate or extent of mitosis. Mitosis is the division of the eukaryotic cell nucleus to produce two daughter nuclei that, usually, contain the identical chromosome complement to their mother. http://purl.obolibrary.org/obo/GO_0045910 negative regulation of DNA recombination http://purl.obolibrary.org/obo/GO_0000018 regulation of DNA recombination Any process that stops, prevents, or reduces the frequency, rate or extent of DNA recombination. http://purl.obolibrary.org/obo/GO_0045911 positive regulation of DNA recombination http://purl.obolibrary.org/obo/GO_0051054 positive regulation of DNA metabolic process Any process that activates or increases the frequency, rate or extent of DNA recombination. http://purl.obolibrary.org/obo/GO_0045920 negative regulation of exocytosis http://purl.obolibrary.org/obo/GO_1903531 negative regulation of secretion by cell Any process that stops, prevents, or reduces the frequency, rate or extent of exocytosis. http://purl.obolibrary.org/obo/GO_0045921 positive regulation of exocytosis http://purl.obolibrary.org/obo/GO_1903532 positive regulation of secretion by cell Any process that activates or increases the frequency, rate or extent of exocytosis. http://purl.obolibrary.org/obo/GO_0045953 negative regulation of natural killer cell mediated cytotoxicity http://purl.obolibrary.org/obo/GO_0042269 regulation of natural killer cell mediated cytotoxicity Any process that stops, prevents, or reduces the rate of natural killer mediated cytotoxicity. http://purl.obolibrary.org/obo/GO_0045954 positive regulation of natural killer cell mediated cytotoxicity http://purl.obolibrary.org/obo/GO_0042269 regulation of natural killer cell mediated cytotoxicity Any process that activates or increases the frequency, rate or extent of natural killer cell mediated cytotoxicity. http://purl.obolibrary.org/obo/GO_0045995 regulation of embryonic development http://purl.obolibrary.org/obo/GO_2000026 regulation of multicellular organismal development Any process that modulates the frequency, rate or extent of embryonic development. http://purl.obolibrary.org/obo/GO_0046165 alcohol biosynthetic process http://purl.obolibrary.org/obo/GO_0044283 small molecule biosynthetic process The chemical reactions and pathways resulting in the formation of alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom. http://purl.obolibrary.org/obo/GO_0046394 carboxylic acid biosynthetic process http://purl.obolibrary.org/obo/GO_0016053 organic acid biosynthetic process The chemical reactions and pathways resulting in the formation of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups. http://purl.obolibrary.org/obo/GO_0046530 photoreceptor cell differentiation http://purl.obolibrary.org/obo/GO_0030182 neuron differentiation The specialization of organization of a photoreceptor, a cell that responds to incident electromagnetic radiation, particularly visible light. An example of this process is found in Drosophila melanogaster. http://purl.obolibrary.org/obo/GO_0046620 regulation of organ growth http://purl.obolibrary.org/obo/GO_0048638 regulation of developmental growth Any process that modulates the frequency, rate or extent of growth of an organ of an organism. http://purl.obolibrary.org/obo/GO_0046629 gamma-delta T cell activation http://purl.obolibrary.org/obo/GO_0042110 T cell activation The change in morphology and behavior of a gamma-delta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. http://purl.obolibrary.org/obo/GO_0046630 gamma-delta T cell proliferation http://purl.obolibrary.org/obo/GO_0046629 gamma-delta T cell activation The expansion of a gamma-delta T cell population by cell division. http://purl.obolibrary.org/obo/GO_0046631 alpha-beta T cell activation http://purl.obolibrary.org/obo/GO_0042110 T cell activation The change in morphology and behavior of an alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. http://purl.obolibrary.org/obo/GO_0046632 alpha-beta T cell differentiation http://purl.obolibrary.org/obo/GO_0046631 alpha-beta T cell activation The process in which a precursor cell type acquires the specialized features of an alpha-beta T cell. An alpha-beta T cell is a T cell that expresses an alpha-beta T cell receptor complex. http://purl.obolibrary.org/obo/GO_0046633 alpha-beta T cell proliferation http://purl.obolibrary.org/obo/GO_0046631 alpha-beta T cell activation The expansion of an alpha-beta T cell population by cell division. http://purl.obolibrary.org/obo/GO_0046649 lymphocyte activation http://purl.obolibrary.org/obo/GO_0045321 leukocyte activation A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor. http://purl.obolibrary.org/obo/GO_0046651 lymphocyte proliferation http://purl.obolibrary.org/obo/GO_0032943 mononuclear cell proliferation The expansion of a lymphocyte population by cell division. http://purl.obolibrary.org/obo/GO_0046661 male sex differentiation http://purl.obolibrary.org/obo/GO_0007548 sex differentiation The establishment of the sex of a male organism by physical differentiation. http://purl.obolibrary.org/obo/GO_0046717 acid secretion http://purl.obolibrary.org/obo/GO_0046903 secretion The controlled release of acid by a cell or a tissue. http://purl.obolibrary.org/obo/GO_0046872 metal ion binding http://purl.obolibrary.org/obo/GO_0043169 cation binding Binding to a metal ion. http://purl.obolibrary.org/obo/GO_0046879 hormone secretion http://purl.obolibrary.org/obo/GO_0023061 signal release The regulated release of hormones, substances with a specific regulatory effect on a particular organ or group of cells. http://purl.obolibrary.org/obo/GO_0046903 secretion http://purl.obolibrary.org/obo/GO_0006810 transport The controlled release of a substance by a cell or a tissue. http://purl.obolibrary.org/obo/GO_0046928 regulation of neurotransmitter secretion http://purl.obolibrary.org/obo/GO_0050804 modulation of chemical synaptic transmission Any process that modulates the frequency, rate or extent of the regulated release of a neurotransmitter from a cell. http://purl.obolibrary.org/obo/GO_0048002 antigen processing and presentation of peptide antigen http://purl.obolibrary.org/obo/GO_0019882 antigen processing and presentation The process in which an antigen-presenting cell expresses peptide antigen in association with an MHC protein complex on its cell surface, including proteolysis and transport steps for the peptide antigen both prior to and following assembly with the MHC protein complex. The peptide antigen is typically, but not always, processed from an endogenous or exogenous protein. http://purl.obolibrary.org/obo/GO_0048143 astrocyte activation http://purl.obolibrary.org/obo/GO_0061900 glial cell activation A change in morphology and behavior of an astrocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. http://purl.obolibrary.org/obo/GO_0048162 multi-layer follicle stage http://purl.obolibrary.org/obo/GO_0022605 mammalian oogenesis stage The stage in oogenesis when many layers of follicle cells surround the oocyte. There is a yolk nucleus (Balbiani's Body) near the germinal vesicle. http://purl.obolibrary.org/obo/GO_0048165 fused antrum stage http://purl.obolibrary.org/obo/GO_0022605 mammalian oogenesis stage The stage in oogenesis when the antral spaces fuse to form a single antral space. The oocyte is suspended in the cumulus oophorous and the first polar body in the perivitelline space. http://purl.obolibrary.org/obo/GO_0048209 regulation of vesicle targeting, to, from or within Golgi http://purl.obolibrary.org/obo/GO_0060341 regulation of cellular localization Any process that modulates the frequency, rate, or destination of vesicle-mediated transport to, from or within the Golgi apparatus. http://purl.obolibrary.org/obo/GO_0048247 lymphocyte chemotaxis http://purl.obolibrary.org/obo/GO_0030595 leukocyte chemotaxis The directed movement of a lymphocyte in response to an external stimulus. http://purl.obolibrary.org/obo/GO_0048284 organelle fusion http://purl.obolibrary.org/obo/GO_0006996 organelle organization The creation of a single organelle from two or more organelles. http://purl.obolibrary.org/obo/GO_0048285 organelle fission http://purl.obolibrary.org/obo/GO_0006996 organelle organization The creation of two or more organelles by division of one organelle. http://purl.obolibrary.org/obo/GO_0048308 organelle inheritance http://purl.obolibrary.org/obo/GO_0006996 organelle organization The partitioning of organelles between daughter cells at cell division. http://purl.obolibrary.org/obo/GO_0048311 mitochondrion distribution http://purl.obolibrary.org/obo/GO_0051646 mitochondrion localization Any process that establishes the spatial arrangement of mitochondria between and within cells. http://purl.obolibrary.org/obo/GO_0048332 mesoderm morphogenesis http://purl.obolibrary.org/obo/GO_0048729 tissue morphogenesis The process in which the anatomical structures of the mesoderm are generated and organized. http://purl.obolibrary.org/obo/GO_0048333 mesodermal cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a mesoderm cell. http://purl.obolibrary.org/obo/GO_0048368 lateral mesoderm development http://purl.obolibrary.org/obo/GO_0060485 mesenchyme development The process whose specific outcome is the progression of the lateral mesoderm over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0048468 cell development http://purl.obolibrary.org/obo/GO_0048869 cellular developmental process The cellular developmental process in which a specific cell progresses from an immature to a mature state. Cell development start once cell commitment has taken place. http://purl.obolibrary.org/obo/GO_0048469 cell maturation http://purl.obolibrary.org/obo/GO_0071695 anatomical structure maturation The cellular developmental process, independent of morphogenetic (shape) change, that is required for a specific cell to attain its fully functional state. http://purl.obolibrary.org/obo/GO_0048505 regulation of timing of cell differentiation http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation The process controlling the activation and/or rate at which relatively unspecialized cells acquire specialized features. Any process that modulates the rate, frequency or extent of the XXX at a consistent predetermined time point during its development. http://purl.obolibrary.org/obo/GO_0048513 animal organ development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. http://purl.obolibrary.org/obo/GO_0048514 blood vessel morphogenesis http://purl.obolibrary.org/obo/GO_0035239 tube morphogenesis The process in which the anatomical structures of blood vessels are generated and organized. The blood vessel is the vasculature carrying blood. http://purl.obolibrary.org/obo/GO_0048518 positive regulation of biological process http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. http://purl.obolibrary.org/obo/GO_0048519 negative regulation of biological process http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process Any process that stops, prevents, or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. http://purl.obolibrary.org/obo/GO_0048562 embryonic organ morphogenesis http://purl.obolibrary.org/obo/GO_0048598 embryonic morphogenesis Morphogenesis, during the embryonic phase, of a tissue or tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. http://purl.obolibrary.org/obo/GO_0048568 embryonic organ development http://purl.obolibrary.org/obo/GO_0048513 animal organ development Development, taking place during the embryonic phase, of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. http://purl.obolibrary.org/obo/GO_0048583 regulation of response to stimulus http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process Any process that modulates the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. http://purl.obolibrary.org/obo/GO_0048584 positive regulation of response to stimulus http://purl.obolibrary.org/obo/GO_0048583 regulation of response to stimulus Any process that activates, maintains or increases the rate of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. http://purl.obolibrary.org/obo/GO_0048585 negative regulation of response to stimulus http://purl.obolibrary.org/obo/GO_0048583 regulation of response to stimulus Any process that stops, prevents, or reduces the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. http://purl.obolibrary.org/obo/GO_0048588 developmental cell growth http://purl.obolibrary.org/obo/GO_0048589 developmental growth The growth of a cell, where growth contributes to the progression of the cell over time from one condition to another. http://purl.obolibrary.org/obo/GO_0048589 developmental growth http://purl.obolibrary.org/obo/GO_0040007 growth The increase in size or mass of an entire organism, a part of an organism or a cell, where the increase in size or mass has the specific outcome of the progression of the organism over time from one condition to another. http://purl.obolibrary.org/obo/GO_0048592 eye morphogenesis http://purl.obolibrary.org/obo/GO_0090596 sensory organ morphogenesis The process in which the anatomical structures of the eye are generated and organized. http://purl.obolibrary.org/obo/GO_0048593 camera-type eye morphogenesis http://purl.obolibrary.org/obo/GO_0048592 eye morphogenesis The process in which the anatomical structures of the eye are generated and organized. The camera-type eye is an organ of sight that receives light through an aperture and focuses it through a lens, projecting it on a photoreceptor field. http://purl.obolibrary.org/obo/GO_0048596 embryonic camera-type eye morphogenesis http://purl.obolibrary.org/obo/GO_0048048 embryonic eye morphogenesis The process in which the anatomical structures of the eye are generated and organized during embryonic development. http://purl.obolibrary.org/obo/GO_0048598 embryonic morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which anatomical structures are generated and organized during the embryonic phase. The embryonic phase begins with zygote formation. The end of the embryonic phase is organism-specific. For example, it would be at birth for mammals, larval hatching for insects and seed dormancy in plants. http://purl.obolibrary.org/obo/GO_0048599 oocyte development http://purl.obolibrary.org/obo/GO_0007281 germ cell development The process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell. http://purl.obolibrary.org/obo/GO_0048608 reproductive structure development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The reproductive developmental process whose specific outcome is the progression of somatic structures that will be used in the process of creating new individuals from one or more parents, from their formation to the mature structures. http://purl.obolibrary.org/obo/GO_0048645 animal organ formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process pertaining to the initial formation of an animal organ from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure, such as inductive events, and ends when the structural rudiment of the organ is recognizable, such as a condensation of mesenchymal cells into the organ rudiment. Organs are a natural part or structure in an animal or a plant, capable of performing some special action (termed its function), which is essential to the life or well-being of the whole. The heart and lungs are organs of animals, and the petal and leaf are organs of plants. In animals the organs are generally made up of several tissues, one of which usually predominates, and determines the principal function of the organ. http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis http://purl.obolibrary.org/obo/GO_0032502 developmental process The developmental process pertaining to the initial formation of an anatomical structure from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome. http://purl.obolibrary.org/obo/GO_0048666 neuron development http://purl.obolibrary.org/obo/GO_0048468 cell development The process whose specific outcome is the progression of a neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. http://purl.obolibrary.org/obo/GO_0048667 cell morphogenesis involved in neuron differentiation http://purl.obolibrary.org/obo/GO_0000902 cell morphogenesis The process in which the structures of a neuron are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a neuron. http://purl.obolibrary.org/obo/GO_0048699 generation of neurons http://purl.obolibrary.org/obo/GO_0022008 neurogenesis The process in which nerve cells are generated. This includes the production of neuroblasts and their differentiation into neurons. http://purl.obolibrary.org/obo/GO_0048705 skeletal system morphogenesis http://purl.obolibrary.org/obo/GO_0009887 animal organ morphogenesis The process in which the anatomical structures of the skeleton are generated and organized. http://purl.obolibrary.org/obo/GO_0048729 tissue morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structures of a tissue are generated and organized. http://purl.obolibrary.org/obo/GO_0048731 system development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process. http://purl.obolibrary.org/obo/GO_0048732 gland development http://purl.obolibrary.org/obo/GO_0048513 animal organ development The process whose specific outcome is the progression of a gland over time, from its formation to the mature structure. A gland is an organ specialised for secretion. http://purl.obolibrary.org/obo/GO_0048733 sebaceous gland development http://purl.obolibrary.org/obo/GO_0048732 gland development The process whose specific outcome is the progression of the sebaceous gland over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0048738 cardiac muscle tissue development http://purl.obolibrary.org/obo/GO_0014706 striated muscle tissue development The process whose specific outcome is the progression of cardiac muscle over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0048749 compound eye development http://purl.obolibrary.org/obo/GO_0001654 eye development The process whose specific outcome is the progression of the compound eye over time, from its formation to the mature structure. The compound eye is an organ of sight that contains multiple repeating units, often arranged hexagonally. Each unit has its own lens and photoreceptor cell(s) and can generate either a single pixelated image or multiple images, per eye. http://purl.obolibrary.org/obo/GO_0048754 branching morphogenesis of an epithelial tube http://purl.obolibrary.org/obo/GO_0061138 morphogenesis of a branching epithelium The process in which the anatomical structures of branches in an epithelial tube are generated and organized. A tube is a long hollow cylinder. http://purl.obolibrary.org/obo/GO_0048762 mesenchymal cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types. http://purl.obolibrary.org/obo/GO_0048771 tissue remodeling http://purl.obolibrary.org/obo/GO_0032501 multicellular organismal process The reorganization or renovation of existing tissues. This process can either change the characteristics of a tissue such as in blood vessel remodeling, or result in the dynamic equilibrium of a tissue such as in bone remodeling. http://purl.obolibrary.org/obo/GO_0048845 venous blood vessel morphogenesis http://purl.obolibrary.org/obo/GO_0048514 blood vessel morphogenesis The process in which the anatomical structures of venous blood vessels are generated and organized. Veins are blood vessels that transport blood from the body and its organs to the heart. http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development http://purl.obolibrary.org/obo/GO_0032502 developmental process The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome. http://purl.obolibrary.org/obo/GO_0048858 cell projection morphogenesis http://purl.obolibrary.org/obo/GO_0030030 cell projection organization The process in which the anatomical structures of a cell projection are generated and organized. http://purl.obolibrary.org/obo/GO_0048869 cellular developmental process http://purl.obolibrary.org/obo/GO_0032502 developmental process A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition. http://purl.obolibrary.org/obo/GO_0048870 cell motility http://purl.obolibrary.org/obo/GO_0009987 cellular process Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another. http://purl.obolibrary.org/obo/GO_0048871 multicellular organismal-level homeostasis http://purl.obolibrary.org/obo/GO_0042592 homeostatic process Any process involved in the maintenance of an internal steady state at the level of the multicellular organism. http://purl.obolibrary.org/obo/GO_0048872 homeostasis of number of cells http://purl.obolibrary.org/obo/GO_0048871 multicellular organismal-level homeostasis Any biological process involved in the maintenance of the steady-state number of cells within a population of cells. http://purl.obolibrary.org/obo/GO_0050673 epithelial cell proliferation http://purl.obolibrary.org/obo/GO_0008283 cell population proliferation The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population. Epithelial cells make up the epithelium, the covering of internal and external surfaces of the body, including the lining of vessels and other small cavities. It consists of cells joined by small amounts of cementing substances. http://purl.obolibrary.org/obo/GO_0050678 regulation of epithelial cell proliferation http://purl.obolibrary.org/obo/GO_0042127 regulation of cell population proliferation Any process that modulates the frequency, rate or extent of epithelial cell proliferation. http://purl.obolibrary.org/obo/GO_0050679 positive regulation of epithelial cell proliferation http://purl.obolibrary.org/obo/GO_0050678 regulation of epithelial cell proliferation Any process that activates or increases the rate or extent of epithelial cell proliferation. http://purl.obolibrary.org/obo/GO_0050680 negative regulation of epithelial cell proliferation http://purl.obolibrary.org/obo/GO_0008285 negative regulation of cell population proliferation Any process that stops, prevents or reduces the rate or extent of epithelial cell proliferation. http://purl.obolibrary.org/obo/GO_0050727 regulation of inflammatory response http://purl.obolibrary.org/obo/GO_0031347 regulation of defense response Any process that modulates the frequency, rate or extent of the inflammatory response, the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. http://purl.obolibrary.org/obo/GO_0050728 negative regulation of inflammatory response http://purl.obolibrary.org/obo/GO_0032102 negative regulation of response to external stimulus Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response. http://purl.obolibrary.org/obo/GO_0050729 positive regulation of inflammatory response http://purl.obolibrary.org/obo/GO_0050727 regulation of inflammatory response Any process that activates or increases the frequency, rate or extent of the inflammatory response. http://purl.obolibrary.org/obo/GO_0050769 positive regulation of neurogenesis http://purl.obolibrary.org/obo/GO_0050767 regulation of neurogenesis Any process that activates or increases the frequency, rate or extent of neurogenesis, the generation of cells within the nervous system. http://purl.obolibrary.org/obo/GO_0050776 regulation of immune response http://purl.obolibrary.org/obo/GO_0048583 regulation of response to stimulus Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus. http://purl.obolibrary.org/obo/GO_0050777 negative regulation of immune response http://purl.obolibrary.org/obo/GO_0050776 regulation of immune response Any process that stops, prevents, or reduces the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus. http://purl.obolibrary.org/obo/GO_0050778 positive regulation of immune response http://purl.obolibrary.org/obo/GO_0050776 regulation of immune response Any process that activates or increases the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus. http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process http://purl.obolibrary.org/obo/GO_0065007 biological regulation Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. http://purl.obolibrary.org/obo/GO_0050806 positive regulation of synaptic transmission http://purl.obolibrary.org/obo/GO_0010647 positive regulation of cell communication Any process that activates or increases the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse. http://purl.obolibrary.org/obo/GO_0050808 synapse organization http://purl.obolibrary.org/obo/GO_0034330 cell junction organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell). http://purl.obolibrary.org/obo/GO_0050865 regulation of cell activation http://purl.obolibrary.org/obo/GO_0051239 regulation of multicellular organismal process Any process that modulates the frequency, rate or extent of cell activation, the change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand. http://purl.obolibrary.org/obo/GO_0050866 negative regulation of cell activation http://purl.obolibrary.org/obo/GO_0051241 negative regulation of multicellular organismal process Any process that stops, prevents, or reduces the frequency, rate or extent of cell activation. http://purl.obolibrary.org/obo/GO_0050867 positive regulation of cell activation http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the frequency, rate or extent of activation. http://purl.obolibrary.org/obo/GO_0050877 nervous system process http://purl.obolibrary.org/obo/GO_0003008 system process An organ system process carried out by any of the organs or tissues of the neurological system. http://purl.obolibrary.org/obo/GO_0050878 regulation of body fluid levels http://purl.obolibrary.org/obo/GO_0065008 regulation of biological quality Any process that modulates the levels of body fluids. http://purl.obolibrary.org/obo/GO_0050881 musculoskeletal movement http://purl.obolibrary.org/obo/GO_0050879 multicellular organismal movement The movement of an organism or part of an organism using mechanoreceptors, the nervous system, striated muscle and/or the skeletal system. http://purl.obolibrary.org/obo/GO_0050886 endocrine process http://purl.obolibrary.org/obo/GO_0003008 system process The process that involves the secretion of or response to endocrine hormones. An endocrine hormone is a hormone released into the circulatory system. http://purl.obolibrary.org/obo/GO_0050891 multicellular organismal-level water homeostasis http://purl.obolibrary.org/obo/GO_0140962 multicellular organismal-level chemical homeostasis A chemical homeostatic process involved in the maintenance of a steady state level of water within extracellular body fluids, such as blood, xylem or phloem, of a multicellular organism. This is distinct from maintenance of cellular homeostasis, which occurs within a cell. http://purl.obolibrary.org/obo/GO_0050900 leukocyte migration http://purl.obolibrary.org/obo/GO_0016477 cell migration The movement of a leukocyte within or between different tissues and organs of the body. http://purl.obolibrary.org/obo/GO_0050905 neuromuscular process http://purl.obolibrary.org/obo/GO_0050877 nervous system process Any process pertaining to the functions of the nervous and muscular systems of an organism. http://purl.obolibrary.org/obo/GO_0050912 detection of chemical stimulus involved in sensory perception of taste http://purl.obolibrary.org/obo/GO_0050907 detection of chemical stimulus involved in sensory perception The series of events involved in the perception of taste in which a gustatory chemical stimulus is received and converted into a molecular signal. http://purl.obolibrary.org/obo/GO_0050920 regulation of chemotaxis http://purl.obolibrary.org/obo/GO_0040012 regulation of locomotion Any process that modulates the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient. http://purl.obolibrary.org/obo/GO_0050921 positive regulation of chemotaxis http://purl.obolibrary.org/obo/GO_0040017 positive regulation of locomotion Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient. http://purl.obolibrary.org/obo/GO_0050922 negative regulation of chemotaxis http://purl.obolibrary.org/obo/GO_0032102 negative regulation of response to external stimulus Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient. http://purl.obolibrary.org/obo/GO_0050982 detection of mechanical stimulus http://purl.obolibrary.org/obo/GO_0009582 detection of abiotic stimulus The series of events by which a mechanical stimulus is received and converted into a molecular signal. http://purl.obolibrary.org/obo/GO_0051046 regulation of secretion http://purl.obolibrary.org/obo/GO_0051049 regulation of transport Any process that modulates the frequency, rate or extent of the controlled release of a substance from a cell or a tissue. http://purl.obolibrary.org/obo/GO_0051047 positive regulation of secretion http://purl.obolibrary.org/obo/GO_0051050 positive regulation of transport Any process that activates or increases the frequency, rate or extent of the controlled release of a substance from a cell or a tissue. http://purl.obolibrary.org/obo/GO_0051048 negative regulation of secretion http://purl.obolibrary.org/obo/GO_0051051 negative regulation of transport Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a substance from a cell or a tissue. http://purl.obolibrary.org/obo/GO_0051052 regulation of DNA metabolic process http://purl.obolibrary.org/obo/GO_0060255 regulation of macromolecule metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving DNA. http://purl.obolibrary.org/obo/GO_0051093 negative regulation of developmental process http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that stops, prevents or reduces the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). http://purl.obolibrary.org/obo/GO_0051094 positive regulation of developmental process http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that activates or increases the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). http://purl.obolibrary.org/obo/GO_0051128 regulation of cellular component organization http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope. http://purl.obolibrary.org/obo/GO_0051132 NK T cell activation http://purl.obolibrary.org/obo/GO_0046631 alpha-beta T cell activation The change in morphology and behavior of a mature or immature natural killer T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. http://purl.obolibrary.org/obo/GO_0051216 cartilage development http://purl.obolibrary.org/obo/GO_0048513 animal organ development The process whose specific outcome is the progression of a cartilage element over time, from its formation to the mature structure. Cartilage elements are skeletal elements that consist of connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate. http://purl.obolibrary.org/obo/GO_0051239 regulation of multicellular organismal process http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs. http://purl.obolibrary.org/obo/GO_0051240 positive regulation of multicellular organismal process http://purl.obolibrary.org/obo/GO_0051239 regulation of multicellular organismal process Any process that activates or increases the frequency, rate or extent of an organismal process, any of the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs. http://purl.obolibrary.org/obo/GO_0051241 negative regulation of multicellular organismal process http://purl.obolibrary.org/obo/GO_0051239 regulation of multicellular organismal process Any process that stops, prevents, or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs. http://purl.obolibrary.org/obo/GO_0051252 regulation of RNA metabolic process http://purl.obolibrary.org/obo/GO_0060255 regulation of macromolecule metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving RNA. http://purl.obolibrary.org/obo/GO_0051254 positive regulation of RNA metabolic process http://purl.obolibrary.org/obo/GO_0051252 regulation of RNA metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving RNA. http://purl.obolibrary.org/obo/GO_0051258 protein polymerization http://purl.obolibrary.org/obo/GO_0065003 protein-containing complex assembly The process of creating protein polymers, compounds composed of a large number of component monomers; polymeric proteins may be made up of different or identical monomers. Polymerization occurs by the addition of extra monomers to an existing poly- or oligomeric protein. http://purl.obolibrary.org/obo/GO_0051276 chromosome organization http://purl.obolibrary.org/obo/GO_0006996 organelle organization A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of chromosomes, structures composed of a very long molecule of DNA and associated proteins that carries hereditary information. This term covers covalent modifications at the molecular level as well as spatial relationships among the major components of a chromosome. http://purl.obolibrary.org/obo/GO_0051301 cell division http://purl.obolibrary.org/obo/GO_0009987 cellular process The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells. http://purl.obolibrary.org/obo/GO_0051302 regulation of cell division http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of the physical partitioning and separation of a cell into daughter cells. http://purl.obolibrary.org/obo/GO_0051321 meiotic cell cycle http://purl.obolibrary.org/obo/GO_0022414 reproductive process Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell via two nuclear divisions. http://purl.obolibrary.org/obo/GO_0051493 regulation of cytoskeleton organization http://purl.obolibrary.org/obo/GO_0033043 regulation of organelle organization Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures. http://purl.obolibrary.org/obo/GO_0051503 adenine nucleotide transport http://purl.obolibrary.org/obo/GO_0015865 purine nucleotide transport The directed movement of adenine nucleotides, ATP, ADP, and/or AMP, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0051590 positive regulation of neurotransmitter transport http://purl.obolibrary.org/obo/GO_0051050 positive regulation of transport Any process that activates or increases the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0051608 histamine transport http://purl.obolibrary.org/obo/GO_0071705 nitrogen compound transport The directed movement of histamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Histamine is a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans. http://purl.obolibrary.org/obo/GO_0051707 response to other organism http://purl.obolibrary.org/obo/GO_0044419 biological process involved in interspecies interaction between organisms Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from another living organism. http://purl.obolibrary.org/obo/GO_0051726 regulation of cell cycle http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that modulates the rate or extent of progression through the cell cycle. http://purl.obolibrary.org/obo/GO_0051899 membrane depolarization http://purl.obolibrary.org/obo/GO_0042391 regulation of membrane potential The process in which membrane potential decreases with respect to its steady-state potential, usually from negative potential to a more positive potential. For example, the initial depolarization during the rising phase of an action potential is in the direction from the negative steady-state resting potential towards the positive membrane potential that will be the peak of the action potential. http://purl.obolibrary.org/obo/GO_0051955 regulation of amino acid transport http://purl.obolibrary.org/obo/GO_0051952 regulation of amine transport Any process that modulates the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0051956 negative regulation of amino acid transport http://purl.obolibrary.org/obo/GO_0051953 negative regulation of amine transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0051957 positive regulation of amino acid transport http://purl.obolibrary.org/obo/GO_0051954 positive regulation of amine transport Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0052803 imidazole-containing compound metabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process The chemical reactions and pathways involving imidazoles, five-membered organic heterocycle containing two nitrogen atoms at positions 1 and 3, or any of its derivatives; compounds containing an imidazole skeleton. http://purl.obolibrary.org/obo/GO_0052805 imidazole-containing compound catabolic process http://purl.obolibrary.org/obo/GO_0009056 catabolic process The chemical reactions and pathways resulting in the breakdown of imidazoles, five-membered organic heterocycle containing two nitrogen atoms at positions 1 and 3, or any of its derivatives; compounds containing an imidazole skeleton. http://purl.obolibrary.org/obo/GO_0055008 cardiac muscle tissue morphogenesis http://purl.obolibrary.org/obo/GO_0060415 muscle tissue morphogenesis The process in which the anatomical structures of cardiac muscle tissue are generated and organized. http://purl.obolibrary.org/obo/GO_0055010 ventricular cardiac muscle tissue morphogenesis http://purl.obolibrary.org/obo/GO_0055008 cardiac muscle tissue morphogenesis The process in which the anatomical structures of cardiac ventricle muscle is generated and organized. http://purl.obolibrary.org/obo/GO_0055017 cardiac muscle tissue growth http://purl.obolibrary.org/obo/GO_0048589 developmental growth The increase in size or mass of a cardiac muscle, where the increase in size or mass has the specific outcome of the progression of the organism over time from one condition to another. http://purl.obolibrary.org/obo/GO_0055082 intracellular chemical homeostasis http://purl.obolibrary.org/obo/GO_0048878 chemical homeostasis A homeostatic process involved in the maintenance of a steady state level of a chemical within a cell. http://purl.obolibrary.org/obo/GO_0060039 pericardium development http://purl.obolibrary.org/obo/GO_0060429 epithelium development The process whose specific outcome is the progression of the pericardium over time, from its formation to the mature structure. The pericardium is a double-walled sac that contains the heart and the roots of the aorta, vena cava and the pulmonary artery. http://purl.obolibrary.org/obo/GO_0060041 retina development in camera-type eye http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the retina over time, from its formation to the mature structure. The retina is the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates. http://purl.obolibrary.org/obo/GO_0060117 auditory receptor cell development http://purl.obolibrary.org/obo/GO_0060119 inner ear receptor cell development The process whose specific outcome is the progression of an auditory receptor cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. http://purl.obolibrary.org/obo/GO_0060135 maternal process involved in female pregnancy http://purl.obolibrary.org/obo/GO_0048609 multicellular organismal reproductive process A reproductive process occurring in the mother that allows an embryo or fetus to develop within it. http://purl.obolibrary.org/obo/GO_0060231 mesenchymal to epithelial transition http://purl.obolibrary.org/obo/GO_0030855 epithelial cell differentiation A transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell. http://purl.obolibrary.org/obo/GO_0060249 anatomical structure homeostasis http://purl.obolibrary.org/obo/GO_0048871 multicellular organismal-level homeostasis A homeostatic process involved in the maintenance of an internal steady state within a defined anatomical structure of an organism, including control of cellular proliferation and death and control of metabolic function. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome. http://purl.obolibrary.org/obo/GO_0060255 regulation of macromolecule metabolic process http://purl.obolibrary.org/obo/GO_0019222 regulation of metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. http://purl.obolibrary.org/obo/GO_0060350 endochondral bone morphogenesis http://purl.obolibrary.org/obo/GO_0060349 bone morphogenesis The process in which bones are generated and organized as a result of the conversion of initial cartilaginous anlage into bone. http://purl.obolibrary.org/obo/GO_0060351 cartilage development involved in endochondral bone morphogenesis http://purl.obolibrary.org/obo/GO_0051216 cartilage development The process whose specific outcome is the progression of the cartilage that will provide a scaffold for mineralization of endochondral bones. http://purl.obolibrary.org/obo/GO_0060379 cardiac muscle cell myoblast differentiation http://purl.obolibrary.org/obo/GO_0045445 myoblast differentiation The process in which a relatively unspecialized cell acquires specialized features of a cardiac myoblast. A cardiac myoblast is a precursor cell that has been committed to a cardiac muscle cell fate but retains the ability to divide and proliferate throughout life. http://purl.obolibrary.org/obo/GO_0060411 cardiac septum morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structure of a cardiac septum is generated and organized. A cardiac septum is a partition that separates parts of the heart. http://purl.obolibrary.org/obo/GO_0060412 ventricular septum morphogenesis http://purl.obolibrary.org/obo/GO_0060411 cardiac septum morphogenesis The developmental process in which a ventricular septum is generated and organized. A ventricular septum is an anatomical structure that separates the lower chambers (ventricles) of the heart from one another. http://purl.obolibrary.org/obo/GO_0060413 atrial septum morphogenesis http://purl.obolibrary.org/obo/GO_0060411 cardiac septum morphogenesis The developmental process in which atrial septum is generated and organized. The atrial septum separates the upper chambers (the atria) of the heart from one another. http://purl.obolibrary.org/obo/GO_0060415 muscle tissue morphogenesis http://purl.obolibrary.org/obo/GO_0048729 tissue morphogenesis The process in which the anatomical structures of muscle tissue are generated and organized. Muscle tissue consists of a set of cells that are part of an organ and carry out a contractive function. http://purl.obolibrary.org/obo/GO_0060419 heart growth http://purl.obolibrary.org/obo/GO_0035265 organ growth The increase in size or mass of the heart. http://purl.obolibrary.org/obo/GO_0060429 epithelium development http://purl.obolibrary.org/obo/GO_0009888 tissue development The process whose specific outcome is the progression of an epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. http://purl.obolibrary.org/obo/GO_0060485 mesenchyme development http://purl.obolibrary.org/obo/GO_0009888 tissue development The process whose specific outcome is the progression of a mesenchymal tissue over time, from its formation to the mature structure. A mesenchymal tissue is made up of loosely packed stellate cells. http://purl.obolibrary.org/obo/GO_0060536 cartilage morphogenesis http://purl.obolibrary.org/obo/GO_0048729 tissue morphogenesis The process in which the anatomical structures of cartilage are generated and organized. http://purl.obolibrary.org/obo/GO_0060538 skeletal muscle organ development http://purl.obolibrary.org/obo/GO_0007517 muscle organ development The progression of a skeletal muscle organ over time from its initial formation to its mature state. A skeletal muscle organ includes the skeletal muscle tissue and its associated connective tissue. http://purl.obolibrary.org/obo/GO_0060560 developmental growth involved in morphogenesis http://purl.obolibrary.org/obo/GO_0048589 developmental growth The increase in size or mass of an anatomical structure that contributes to the structure attaining its shape. http://purl.obolibrary.org/obo/GO_0060561 apoptotic process involved in morphogenesis http://purl.obolibrary.org/obo/GO_1902742 apoptotic process involved in development Any apoptotic process that contributes to the shaping of an anatomical structure. http://purl.obolibrary.org/obo/GO_0060562 epithelial tube morphogenesis http://purl.obolibrary.org/obo/GO_0002009 morphogenesis of an epithelium The process in which the anatomical structures of a tube are generated and organized from an epithelium. Epithelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system. http://purl.obolibrary.org/obo/GO_0060563 neuroepithelial cell differentiation http://purl.obolibrary.org/obo/GO_0002065 columnar/cuboidal epithelial cell differentiation The process in which epiblast cells acquire specialized features of neuroepithelial cells. http://purl.obolibrary.org/obo/GO_0060571 morphogenesis of an epithelial fold http://purl.obolibrary.org/obo/GO_0002009 morphogenesis of an epithelium The morphogenetic process in which an epithelial sheet bends along a linear axis. http://purl.obolibrary.org/obo/GO_0060632 regulation of microtubule-based movement http://purl.obolibrary.org/obo/GO_0032886 regulation of microtubule-based process Any process that modulates the rate, frequency, or extent of microtubule-based movement, the movement of organelles, other microtubules and other particles along microtubules, mediated by motor proteins. http://purl.obolibrary.org/obo/GO_0060675 ureteric bud morphogenesis http://purl.obolibrary.org/obo/GO_0072171 mesonephric tubule morphogenesis The process in which the ureteric bud is generated and organized. http://purl.obolibrary.org/obo/GO_0060759 regulation of response to cytokine stimulus http://purl.obolibrary.org/obo/GO_0048583 regulation of response to stimulus Any process that modulates the rate, frequency, or extent of a response to cytokine stimulus. http://purl.obolibrary.org/obo/GO_0060760 positive regulation of response to cytokine stimulus http://purl.obolibrary.org/obo/GO_0060759 regulation of response to cytokine stimulus Any process that increases the rate, frequency, or extent of a response to cytokine stimulus. http://purl.obolibrary.org/obo/GO_0060761 negative regulation of response to cytokine stimulus http://purl.obolibrary.org/obo/GO_0060759 regulation of response to cytokine stimulus Any process that decreases the rate, frequency, or extent of a response to cytokine stimulus. http://purl.obolibrary.org/obo/GO_0060788 ectodermal placode formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The developmental process in which an ectodermal placode forms. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm. http://purl.obolibrary.org/obo/GO_0060795 cell fate commitment involved in formation of primary germ layer http://purl.obolibrary.org/obo/GO_0045165 cell fate commitment The commitment of cells to specific cell fates of the endoderm, ectoderm, or mesoderm as a part of gastrulation. http://purl.obolibrary.org/obo/GO_0060841 venous blood vessel development http://purl.obolibrary.org/obo/GO_0001568 blood vessel development The progression of the venous blood vessel over time from its initial formation to the mature structure. Venous blood vessels carry blood back to the heart after the capillary bed. http://purl.obolibrary.org/obo/GO_0060900 embryonic camera-type eye formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The developmental process pertaining to the initial formation of a camera-type eye from unspecified neurectoderm. This process begins with the differentiation of cells that form the optic field and ends when the optic cup has attained its shape. http://purl.obolibrary.org/obo/GO_0060914 heart formation http://purl.obolibrary.org/obo/GO_0048645 animal organ formation The developmental process pertaining to the initial formation of the heart from unspecified parts. This process begins with the specific processes that contribute to the appearance of the heart field and the arrival of cardiac neural crest to the heart region. The process ends when the structural rudiment is recognizable. http://purl.obolibrary.org/obo/GO_0060932 His-Purkinje system cell differentiation http://purl.obolibrary.org/obo/GO_0055007 cardiac muscle cell differentiation The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell of the His-Purkinje system. These cells form the fibers regulate cardiac muscle contraction in the ventricles. http://purl.obolibrary.org/obo/GO_0060973 cell migration involved in heart development http://purl.obolibrary.org/obo/GO_0016477 cell migration The orderly movement of a cell from one site to another that will contribute to the progression of the heart over time, from its initial formation, to the mature organ. http://purl.obolibrary.org/obo/GO_0060974 cell migration involved in heart formation http://purl.obolibrary.org/obo/GO_0060973 cell migration involved in heart development The orderly movement of a cell from one site to another that contribute to the formation of the heart. The initial heart structure is made up of mesoderm-derived heart progenitor cells and neural crest-derived cells. http://purl.obolibrary.org/obo/GO_0060976 coronary vasculature development http://purl.obolibrary.org/obo/GO_0001568 blood vessel development The process whose specific outcome is the progression of the blood vessels of the heart over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0060977 coronary vasculature morphogenesis http://purl.obolibrary.org/obo/GO_0048514 blood vessel morphogenesis The process in which the anatomical structures of blood vessels of the heart are generated and organized. The blood vessel is the vasculature carrying blood. http://purl.obolibrary.org/obo/GO_0060993 kidney morphogenesis http://purl.obolibrary.org/obo/GO_0009887 animal organ morphogenesis Morphogenesis of a kidney. A kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine. http://purl.obolibrary.org/obo/GO_0061008 hepaticobiliary system development http://purl.obolibrary.org/obo/GO_0048731 system development The progression of the hepaticobiliary system over time, from its formation to the mature structure. The hepaticobiliary system is responsible for metabolic and catabolic processing of small molecules absorbed from the blood or gut, hormones and serum proteins, detoxification, storage of glycogen, triglycerides, metals and lipid soluble vitamins and excretion of bile. Included are the synthesis of albumin, blood coagulation factors, complement, and specific binding proteins. http://purl.obolibrary.org/obo/GO_0061025 membrane fusion http://purl.obolibrary.org/obo/GO_0061024 membrane organization The membrane organization process that joins two lipid bilayers to form a single membrane. http://purl.obolibrary.org/obo/GO_0061035 regulation of cartilage development http://purl.obolibrary.org/obo/GO_2000026 regulation of multicellular organismal development Any process that modulates the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate. http://purl.obolibrary.org/obo/GO_0061049 cell growth involved in cardiac muscle cell development http://purl.obolibrary.org/obo/GO_0048588 developmental cell growth The growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state. http://purl.obolibrary.org/obo/GO_0061053 somite development http://purl.obolibrary.org/obo/GO_0060429 epithelium development The progression of a somite from its initial formation to the mature structure. Somites are mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo. http://purl.obolibrary.org/obo/GO_0061081 positive regulation of myeloid leukocyte cytokine production involved in immune response http://purl.obolibrary.org/obo/GO_0002720 positive regulation of cytokine production involved in immune response Any process that modulates the rate, frequency, or extent of the production of a cytokine that contributes to the immune response. http://purl.obolibrary.org/obo/GO_0061082 myeloid leukocyte cytokine production http://purl.obolibrary.org/obo/GO_0002367 cytokine production involved in immune response Any process that contributes to cytokine production by a myeloid cell. http://purl.obolibrary.org/obo/GO_0061308 cardiac neural crest cell development involved in heart development http://purl.obolibrary.org/obo/GO_0014032 neural crest cell development The process aimed at the progression of a cardiac neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell that contributes to the development of the heart. http://purl.obolibrary.org/obo/GO_0061309 cardiac neural crest cell development involved in outflow tract morphogenesis http://purl.obolibrary.org/obo/GO_0061308 cardiac neural crest cell development involved in heart development The process aimed at the progression of a cardiac neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell that contributes to the shaping of the outflow tract. http://purl.obolibrary.org/obo/GO_0061311 cell surface receptor signaling pathway involved in heart development http://purl.obolibrary.org/obo/GO_0007166 cell surface receptor signaling pathway The series of molecular signals initiated by a ligand the binding to its receptor on the surface of a cell, which contributes to the progression of the heart over time. http://purl.obolibrary.org/obo/GO_0061323 cell proliferation involved in heart morphogenesis http://purl.obolibrary.org/obo/GO_0008283 cell population proliferation The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to the shaping of the heart. http://purl.obolibrary.org/obo/GO_0061343 cell adhesion involved in heart morphogenesis http://purl.obolibrary.org/obo/GO_0007155 cell adhesion The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules that contributes to the shaping of the heart. http://purl.obolibrary.org/obo/GO_0061384 heart trabecula morphogenesis http://purl.obolibrary.org/obo/GO_0061383 trabecula morphogenesis The process of shaping a trabecula in the heart. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue. http://purl.obolibrary.org/obo/GO_0061448 connective tissue development http://purl.obolibrary.org/obo/GO_0009888 tissue development The progression of a connective tissue over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0061844 antimicrobial humoral immune response mediated by antimicrobial peptide http://purl.obolibrary.org/obo/GO_0019730 antimicrobial humoral response An immune response against microbes mediated by anti-microbial peptides in body fluid. http://purl.obolibrary.org/obo/GO_0065005 protein-lipid complex assembly http://purl.obolibrary.org/obo/GO_0071825 protein-lipid complex organization The aggregation, arrangement and bonding together of proteins and lipids to form a protein-lipid complex. http://purl.obolibrary.org/obo/GO_0065008 regulation of biological quality http://purl.obolibrary.org/obo/GO_0065007 biological regulation Any process that modulates a qualitative or quantitative trait of a biological quality. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc. http://purl.obolibrary.org/obo/GO_0070227 lymphocyte apoptotic process http://purl.obolibrary.org/obo/GO_0071887 leukocyte apoptotic process Any apoptotic process in a lymphocyte, a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin. http://purl.obolibrary.org/obo/GO_0070228 regulation of lymphocyte apoptotic process http://purl.obolibrary.org/obo/GO_2000106 regulation of leukocyte apoptotic process Any process that modulates the occurrence or rate of lymphocyte death by apoptotic process. http://purl.obolibrary.org/obo/GO_0070229 negative regulation of lymphocyte apoptotic process http://purl.obolibrary.org/obo/GO_2000107 negative regulation of leukocyte apoptotic process Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte death by apoptotic process. http://purl.obolibrary.org/obo/GO_0070230 positive regulation of lymphocyte apoptotic process http://purl.obolibrary.org/obo/GO_2000108 positive regulation of leukocyte apoptotic process Any process that activates or increases the frequency, rate or extent of lymphocyte death by apoptotic process. http://purl.obolibrary.org/obo/GO_0070252 actin-mediated cell contraction http://purl.obolibrary.org/obo/GO_0030048 actin filament-based movement The actin filament-based process in which cytoplasmic actin filaments slide past one another resulting in contraction of all or part of the cell body. http://purl.obolibrary.org/obo/GO_0070278 extracellular matrix constituent secretion http://purl.obolibrary.org/obo/GO_0032940 secretion by cell The controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell. http://purl.obolibrary.org/obo/GO_0070482 response to oxygen levels http://purl.obolibrary.org/obo/GO_0009628 response to abiotic stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of oxygen. http://purl.obolibrary.org/obo/GO_0070483 detection of hypoxia http://purl.obolibrary.org/obo/GO_0003032 detection of oxygen The series of events in which a stimulus indicating lowered oxygen tension is received by a cell and converted into a molecular signal. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level. http://purl.obolibrary.org/obo/GO_0070586 cell-cell adhesion involved in gastrulation http://purl.obolibrary.org/obo/GO_0098609 cell-cell adhesion The attachment of one cell to another cell affecting gastrulation. http://purl.obolibrary.org/obo/GO_0070661 leukocyte proliferation http://purl.obolibrary.org/obo/GO_0008283 cell population proliferation The expansion of a leukocyte population by cell division. http://purl.obolibrary.org/obo/GO_0070887 cellular response to chemical stimulus http://purl.obolibrary.org/obo/GO_0042221 response to chemical Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus. http://purl.obolibrary.org/obo/GO_0070925 organelle assembly http://purl.obolibrary.org/obo/GO_0022607 cellular component assembly The aggregation, arrangement and bonding together of a set of components to form an organelle. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane. http://purl.obolibrary.org/obo/GO_0071248 cellular response to metal ion http://purl.obolibrary.org/obo/GO_0010038 response to metal ion Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metal ion stimulus. http://purl.obolibrary.org/obo/GO_0071621 granulocyte chemotaxis http://purl.obolibrary.org/obo/GO_0097530 granulocyte migration The movement of a granulocyte in response to an external stimulus. http://purl.obolibrary.org/obo/GO_0071674 mononuclear cell migration http://purl.obolibrary.org/obo/GO_0050900 leukocyte migration The movement of a mononuclear cell within or between different tissues and organs of the body. http://purl.obolibrary.org/obo/GO_0071695 anatomical structure maturation http://purl.obolibrary.org/obo/GO_0021700 developmental maturation A developmental process, independent of morphogenetic (shape) change, that is required for an anatomical structure to attain its fully functional state. http://purl.obolibrary.org/obo/GO_0071709 membrane assembly http://purl.obolibrary.org/obo/GO_0022607 cellular component assembly The aggregation, arrangement and bonding together of a set of components to form a membrane. http://purl.obolibrary.org/obo/GO_0071887 leukocyte apoptotic process http://purl.obolibrary.org/obo/GO_0006915 apoptotic process Any apoptotic process in a leukocyte, an achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue. http://purl.obolibrary.org/obo/GO_0071897 DNA biosynthetic process http://purl.obolibrary.org/obo/GO_0006259 DNA metabolic process The biosynthetic process resulting in the formation of DNA. http://purl.obolibrary.org/obo/GO_0072001 renal system development http://purl.obolibrary.org/obo/GO_0048731 system development The process whose specific outcome is the progression of the renal system over time, from its formation to the mature structure. The renal system maintains fluid balance and contributes to electrolyte balance, acid/base balance, and disposal of nitrogenous waste products. In humans, the renal system comprises a pair of kidneys, a pair of ureters, urinary bladder, urethra, sphincter muscle and associated blood vessels. http://purl.obolibrary.org/obo/GO_0072132 mesenchyme morphogenesis http://purl.obolibrary.org/obo/GO_0048729 tissue morphogenesis The process in which the anatomical structures of a mesenchymal tissue are generated and organized. A mesenchymal tissue is made up of loosely packed stellate cells. http://purl.obolibrary.org/obo/GO_0072164 mesonephric tubule development http://purl.obolibrary.org/obo/GO_0072163 mesonephric epithelium development The progression of a mesonephric tubule over time, from its initial formation to the mature structure. A mesonephric tubule is an epithelial tube that is part of the mesonephros. http://purl.obolibrary.org/obo/GO_0072175 epithelial tube formation http://purl.obolibrary.org/obo/GO_0035148 tube formation The developmental process pertaining to the initial formation of an epithelial tube. http://purl.obolibrary.org/obo/GO_0072215 regulation of metanephros development http://purl.obolibrary.org/obo/GO_0090183 regulation of kidney development Any process that modulates the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine. http://purl.obolibrary.org/obo/GO_0072217 negative regulation of metanephros development http://purl.obolibrary.org/obo/GO_0090185 negative regulation of kidney development Any process that decreases the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine. http://purl.obolibrary.org/obo/GO_0072283 metanephric renal vesicle morphogenesis http://purl.obolibrary.org/obo/GO_0072077 renal vesicle morphogenesis The process in which the anatomical structures of the metanephric renal vesicle are generated and organized. The renal vesicle is the primordial structure of the metanephric nephron epithelium, and is formed by the condensation of mesenchymal cells. http://purl.obolibrary.org/obo/GO_0072330 monocarboxylic acid biosynthetic process http://purl.obolibrary.org/obo/GO_0046394 carboxylic acid biosynthetic process The chemical reactions and pathways resulting in the formation of monocarboxylic acids, any organic acid containing one carboxyl (-COOH) group. http://purl.obolibrary.org/obo/GO_0072341 modified amino acid binding http://purl.obolibrary.org/obo/GO_0005488 binding Binding to a modified amino acid. http://purl.obolibrary.org/obo/GO_0072348 sulfur compound transport http://purl.obolibrary.org/obo/GO_0006810 transport The directed movement of compounds that contain sulfur, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0072349 modified amino acid transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity Enables the transfer of modified amino acids from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0072593 reactive oxygen species metabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process The chemical reactions and pathways involving a reactive oxygen species, any molecules or ions formed by the incomplete one-electron reduction of oxygen. They contribute to the microbicidal activity of phagocytes, regulation of signal transduction and gene expression, and the oxidative damage to biopolymers. http://purl.obolibrary.org/obo/GO_0080135 regulation of cellular response to stress http://purl.obolibrary.org/obo/GO_0080134 regulation of response to stress Any process that modulates the frequency, rate or extent of a cellular response to stress. Cellular response to stress is a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). http://purl.obolibrary.org/obo/GO_0090087 regulation of peptide transport http://purl.obolibrary.org/obo/GO_0051049 regulation of transport Any process that modulates the frequency, rate or extent of the directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0090171 chondrocyte morphogenesis http://purl.obolibrary.org/obo/GO_0000902 cell morphogenesis The process in which the structures of a chondrocyte are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a chondrocyte. http://purl.obolibrary.org/obo/GO_0090174 organelle membrane fusion http://purl.obolibrary.org/obo/GO_0061025 membrane fusion The joining of two lipid bilayers to form a single organelle membrane. http://purl.obolibrary.org/obo/GO_0090594 inflammatory response to wounding http://purl.obolibrary.org/obo/GO_0009611 response to wounding The immediate defensive reaction by vertebrate tissue to injury caused by chemical or physical agents. http://purl.obolibrary.org/obo/GO_0090715 immunological memory formation process http://purl.obolibrary.org/obo/GO_0090713 immunological memory process Any immunological memory process that can contribute to the formation of immunological memory. http://purl.obolibrary.org/obo/GO_0097028 dendritic cell differentiation http://purl.obolibrary.org/obo/GO_1903131 mononuclear cell differentiation The process in which a precursor cell type acquires the specialized features of a dendritic cell. A dendritic cell is a leukocyte of dendritic lineage specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation. http://purl.obolibrary.org/obo/GO_0097190 apoptotic signaling pathway http://purl.obolibrary.org/obo/GO_0007165 signal transduction The series of molecular signals which triggers the apoptotic death of a cell. The pathway starts with reception of a signal, and ends when the execution phase of apoptosis is triggered. http://purl.obolibrary.org/obo/GO_0097191 extrinsic apoptotic signaling pathway http://purl.obolibrary.org/obo/GO_0097190 apoptotic signaling pathway The series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with either a ligand binding to a cell surface receptor, or a ligand being withdrawn from a cell surface receptor (e.g. in the case of signaling by dependence receptors), and ends when the execution phase of apoptosis is triggered. http://purl.obolibrary.org/obo/GO_0097205 renal filtration http://purl.obolibrary.org/obo/GO_0003014 renal system process A renal system process in which fluid circulating through the body is filtered through a barrier system. http://purl.obolibrary.org/obo/GO_0097367 carbohydrate derivative binding http://purl.obolibrary.org/obo/GO_0005488 binding Binding to a carbohydrate derivative. http://purl.obolibrary.org/obo/GO_0097529 myeloid leukocyte migration http://purl.obolibrary.org/obo/GO_0050900 leukocyte migration The movement of a myeloid leukocyte within or between different tissues and organs of the body. http://purl.obolibrary.org/obo/GO_0097531 mast cell migration http://purl.obolibrary.org/obo/GO_0097529 myeloid leukocyte migration The movement of a mast cell within or between different tissues and organs of the body. http://purl.obolibrary.org/obo/GO_0097642 calcitonin family receptor activity http://purl.obolibrary.org/obo/GO_0008528 G protein-coupled peptide receptor activity Combining with any member of the calcitonin family (e.g. adrenomedullin, adrenomedullin 2 (intermedin), amylin, calcitonin and calcitonin gene-related peptides (CGRPs)) to initiate a change in cell activity. http://purl.obolibrary.org/obo/GO_0098542 defense response to other organism http://purl.obolibrary.org/obo/GO_0051707 response to other organism Reactions triggered in response to the presence of another organism that act to protect the cell or organism from damage caused by that organism. http://purl.obolibrary.org/obo/GO_0098588 bounding membrane of organelle http://purl.obolibrary.org/obo/GO_0031090 organelle membrane The lipid bilayer that forms the outer-most layer of an organelle. http://purl.obolibrary.org/obo/GO_0098657 import into cell http://purl.obolibrary.org/obo/GO_0006810 transport The directed movement of some substance from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis. http://purl.obolibrary.org/obo/GO_0098773 skin epidermis development http://purl.obolibrary.org/obo/GO_0008544 epidermis development The process whose specific outcome is the progression of the skin epidermis over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0098796 membrane protein complex http://purl.obolibrary.org/obo/GO_0032991 protein-containing complex Any protein complex that is part of a membrane. http://purl.obolibrary.org/obo/GO_0098797 plasma membrane protein complex http://purl.obolibrary.org/obo/GO_0098796 membrane protein complex Any protein complex that is part of the plasma membrane. http://purl.obolibrary.org/obo/GO_0098799 outer mitochondrial membrane protein complex http://purl.obolibrary.org/obo/GO_0098796 membrane protein complex Any protein complex that is part of the outer mitochondrial membrane. http://purl.obolibrary.org/obo/GO_0098801 regulation of renal system process http://purl.obolibrary.org/obo/GO_0044057 regulation of system process Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by the renal system. http://purl.obolibrary.org/obo/GO_0098813 nuclear chromosome segregation http://purl.obolibrary.org/obo/GO_0007059 chromosome segregation The process in which genetic material, in the form of nuclear chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. Nuclear chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles. http://purl.obolibrary.org/obo/GO_0098852 lytic vacuole membrane http://purl.obolibrary.org/obo/GO_0005774 vacuolar membrane The lipid bilayer surrounding a lytic vacuole and separating its contents from the cytoplasm of the cell. http://purl.obolibrary.org/obo/GO_0098868 bone growth http://purl.obolibrary.org/obo/GO_0035265 organ growth The increase in size or mass of a bone that contributes to the shaping of that bone. http://purl.obolibrary.org/obo/GO_0098988 G protein-coupled glutamate receptor activity http://purl.obolibrary.org/obo/GO_0004930 G protein-coupled receptor activity Combining with glutamate and transmitting a signal from one side of the membrane to the other by activating an associated G-protein, initiating a change in cell activity. http://purl.obolibrary.org/obo/GO_0099512 supramolecular fiber http://purl.obolibrary.org/obo/GO_0099081 supramolecular polymer A polymer consisting of an indefinite number of protein or protein complex subunits that have polymerised to form a fiber-shaped structure. http://purl.obolibrary.org/obo/GO_0099513 polymeric cytoskeletal fiber http://purl.obolibrary.org/obo/GO_0099512 supramolecular fiber A component of the cytoskeleton consisting of a homo or heteropolymeric fiber constructed from an indeterminate number of protein subunits. http://purl.obolibrary.org/obo/GO_0099612 protein localization to axon http://purl.obolibrary.org/obo/GO_0008104 intracellular protein localization A process in which a protein is transported to or maintained in a location within an axon. http://purl.obolibrary.org/obo/GO_1900150 regulation of defense response to fungus http://purl.obolibrary.org/obo/GO_0031347 regulation of defense response Any process that modulates the frequency, rate or extent of defense response to fungus. http://purl.obolibrary.org/obo/GO_1900424 regulation of defense response to bacterium http://purl.obolibrary.org/obo/GO_0031347 regulation of defense response Any process that modulates the frequency, rate or extent of defense response to bacterium. http://purl.obolibrary.org/obo/GO_1900425 negative regulation of defense response to bacterium http://purl.obolibrary.org/obo/GO_0032102 negative regulation of response to external stimulus Any process that stops, prevents or reduces the frequency, rate or extent of defense response to bacterium. http://purl.obolibrary.org/obo/GO_1900426 positive regulation of defense response to bacterium http://purl.obolibrary.org/obo/GO_1900424 regulation of defense response to bacterium Any process that activates or increases the frequency, rate or extent of defense response to bacterium. http://purl.obolibrary.org/obo/GO_1901265 nucleoside phosphate binding http://purl.obolibrary.org/obo/GO_0005488 binding Binding to nucleoside phosphate. http://purl.obolibrary.org/obo/GO_1901363 heterocyclic compound binding http://purl.obolibrary.org/obo/GO_0036094 small molecule binding Binding to heterocyclic compound. http://purl.obolibrary.org/obo/GO_1901605 alpha-amino acid metabolic process http://purl.obolibrary.org/obo/GO_0006520 amino acid metabolic process The chemical reactions and pathways involving an alpha-amino acid. http://purl.obolibrary.org/obo/GO_1901607 alpha-amino acid biosynthetic process http://purl.obolibrary.org/obo/GO_1901605 alpha-amino acid metabolic process The chemical reactions and pathways resulting in the formation of an alpha-amino acid. http://purl.obolibrary.org/obo/GO_1901681 sulfur compound binding http://purl.obolibrary.org/obo/GO_0005488 binding Binding to a sulfur compound. http://purl.obolibrary.org/obo/GO_1901682 sulfur compound transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity Enables the transfer of a sulfur compound from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_1901700 response to oxygen-containing compound http://purl.obolibrary.org/obo/GO_0042221 response to chemical Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen-containing compound stimulus. http://purl.obolibrary.org/obo/GO_1902105 regulation of leukocyte differentiation http://purl.obolibrary.org/obo/GO_1903706 regulation of hemopoiesis Any process that modulates the frequency, rate or extent of leukocyte differentiation. http://purl.obolibrary.org/obo/GO_1902106 negative regulation of leukocyte differentiation http://purl.obolibrary.org/obo/GO_1903707 negative regulation of hemopoiesis Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte differentiation. http://purl.obolibrary.org/obo/GO_1902107 positive regulation of leukocyte differentiation http://purl.obolibrary.org/obo/GO_1903708 positive regulation of hemopoiesis Any process that activates or increases the frequency, rate or extent of leukocyte differentiation. http://purl.obolibrary.org/obo/GO_1902275 regulation of chromatin organization http://purl.obolibrary.org/obo/GO_0051128 regulation of cellular component organization Any process that modulates the frequency, rate or extent of chromatin organization. http://purl.obolibrary.org/obo/GO_1902369 negative regulation of RNA catabolic process http://purl.obolibrary.org/obo/GO_0009895 negative regulation of catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of RNA catabolic process. http://purl.obolibrary.org/obo/GO_1902494 catalytic complex http://purl.obolibrary.org/obo/GO_0032991 protein-containing complex A protein complex which is capable of catalytic activity. http://purl.obolibrary.org/obo/GO_1902692 regulation of neuroblast proliferation http://purl.obolibrary.org/obo/GO_2000177 regulation of neural precursor cell proliferation Any process that modulates the frequency, rate or extent of neuroblast proliferation. http://purl.obolibrary.org/obo/GO_1902742 apoptotic process involved in development http://purl.obolibrary.org/obo/GO_0006915 apoptotic process Any apoptotic process that is involved in anatomical structure development. http://purl.obolibrary.org/obo/GO_1903010 regulation of bone development http://purl.obolibrary.org/obo/GO_2000026 regulation of multicellular organismal development Any process that modulates the frequency, rate or extent of bone development. http://purl.obolibrary.org/obo/GO_1903046 meiotic cell cycle process http://purl.obolibrary.org/obo/GO_0022414 reproductive process A process that is part of the meiotic cell cycle. http://purl.obolibrary.org/obo/GO_1903047 mitotic cell cycle process http://purl.obolibrary.org/obo/GO_0022402 cell cycle process A process that is part of the mitotic cell cycle. http://purl.obolibrary.org/obo/GO_1903053 regulation of extracellular matrix organization http://purl.obolibrary.org/obo/GO_0051128 regulation of cellular component organization Any process that modulates the frequency, rate or extent of extracellular matrix organization. http://purl.obolibrary.org/obo/GO_1903054 negative regulation of extracellular matrix organization http://purl.obolibrary.org/obo/GO_0051129 negative regulation of cellular component organization Any process that stops, prevents or reduces the frequency, rate or extent of extracellular matrix organization. http://purl.obolibrary.org/obo/GO_1903055 positive regulation of extracellular matrix organization http://purl.obolibrary.org/obo/GO_0051130 positive regulation of cellular component organization Any process that activates or increases the frequency, rate or extent of extracellular matrix organization. http://purl.obolibrary.org/obo/GO_1903409 reactive oxygen species biosynthetic process http://purl.obolibrary.org/obo/GO_0072593 reactive oxygen species metabolic process The chemical reactions and pathways resulting in the formation of reactive oxygen species, any molecules or ions formed by the incomplete one-electron reduction of oxygen. http://purl.obolibrary.org/obo/GO_1903530 regulation of secretion by cell http://purl.obolibrary.org/obo/GO_0051046 regulation of secretion Any process that modulates the frequency, rate or extent of secretion by cell. http://purl.obolibrary.org/obo/GO_1903531 negative regulation of secretion by cell http://purl.obolibrary.org/obo/GO_1903530 regulation of secretion by cell Any process that stops, prevents or reduces the frequency, rate or extent of secretion by cell. http://purl.obolibrary.org/obo/GO_1903532 positive regulation of secretion by cell http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the frequency, rate or extent of secretion by cell. http://purl.obolibrary.org/obo/GO_1903578 regulation of ATP metabolic process http://purl.obolibrary.org/obo/GO_1900542 regulation of purine nucleotide metabolic process Any process that modulates the frequency, rate or extent of ATP metabolic process. http://purl.obolibrary.org/obo/GO_1904746 negative regulation of apoptotic process involved in development http://purl.obolibrary.org/obo/GO_1904748 regulation of apoptotic process involved in development Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in development. http://purl.obolibrary.org/obo/GO_1904747 positive regulation of apoptotic process involved in development http://purl.obolibrary.org/obo/GO_0043065 positive regulation of apoptotic process Any process that activates or increases the frequency, rate or extent of apoptotic process involved in development. http://purl.obolibrary.org/obo/GO_1904748 regulation of apoptotic process involved in development http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of apoptotic process involved in development. http://purl.obolibrary.org/obo/GO_1905039 carboxylic acid transmembrane transport http://purl.obolibrary.org/obo/GO_0055085 transmembrane transport The process in which carboxylic acid is transported across a membrane. http://purl.obolibrary.org/obo/GO_1905145 cellular response to acetylcholine http://purl.obolibrary.org/obo/GO_1901701 cellular response to oxygen-containing compound Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetylcholine stimulus. http://purl.obolibrary.org/obo/GO_1905330 regulation of morphogenesis of an epithelium http://purl.obolibrary.org/obo/GO_0022603 regulation of anatomical structure morphogenesis Any process that modulates the frequency, rate or extent of morphogenesis of an epithelium. http://purl.obolibrary.org/obo/GO_1905331 negative regulation of morphogenesis of an epithelium http://purl.obolibrary.org/obo/GO_1905330 regulation of morphogenesis of an epithelium Any process that stops, prevents or reduces the frequency, rate or extent of morphogenesis of an epithelium. http://purl.obolibrary.org/obo/GO_1990234 transferase complex http://purl.obolibrary.org/obo/GO_1902494 catalytic complex A protein complex capable of catalyzing the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). http://purl.obolibrary.org/obo/GO_1990845 adaptive thermogenesis http://purl.obolibrary.org/obo/GO_0001659 temperature homeostasis The regulated production of heat in response to short term environmental changes, such as stress, diet or reduced temperature. http://purl.obolibrary.org/obo/GO_2000026 regulation of multicellular organismal development http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of multicellular organismal development. http://purl.obolibrary.org/obo/GO_2000027 regulation of animal organ morphogenesis http://purl.obolibrary.org/obo/GO_0022603 regulation of anatomical structure morphogenesis Any process that modulates the frequency, rate or extent of animal organ morphogenesis. http://purl.obolibrary.org/obo/GO_2000114 regulation of establishment of cell polarity http://purl.obolibrary.org/obo/GO_0032878 regulation of establishment or maintenance of cell polarity Any process that modulates the frequency, rate or extent of establishment of cell polarity. http://purl.obolibrary.org/obo/GO_2000136 regulation of cell proliferation involved in heart morphogenesis http://purl.obolibrary.org/obo/GO_0042127 regulation of cell population proliferation Any process that modulates the frequency, rate or extent of cell proliferation involved in heart morphogenesis. http://purl.obolibrary.org/obo/GO_2000137 negative regulation of cell proliferation involved in heart morphogenesis http://purl.obolibrary.org/obo/GO_0008285 negative regulation of cell population proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of cell proliferation involved in heart morphogenesis. http://purl.obolibrary.org/obo/GO_2000138 positive regulation of cell proliferation involved in heart morphogenesis http://purl.obolibrary.org/obo/GO_2000136 regulation of cell proliferation involved in heart morphogenesis Any process that activates or increases the frequency, rate or extent of cell proliferation involved in heart morphogenesis. http://purl.obolibrary.org/obo/GO_2000179 positive regulation of neural precursor cell proliferation http://purl.obolibrary.org/obo/GO_2000177 regulation of neural precursor cell proliferation Any process that activates or increases the frequency, rate or extent of neural precursor cell proliferation. http://purl.obolibrary.org/obo/GO_2000648 positive regulation of stem cell proliferation http://purl.obolibrary.org/obo/GO_0072091 regulation of stem cell proliferation Any process that activates or increases the frequency, rate or extent of stem cell proliferation. http://purl.obolibrary.org/obo/GO_2000696 regulation of epithelial cell differentiation involved in kidney development http://purl.obolibrary.org/obo/GO_0030856 regulation of epithelial cell differentiation Any process that modulates the frequency, rate or extent of epithelial cell differentiation involved in kidney development. http://purl.obolibrary.org/obo/GO_2000697 negative regulation of epithelial cell differentiation involved in kidney development http://purl.obolibrary.org/obo/GO_2000696 regulation of epithelial cell differentiation involved in kidney development Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell differentiation involved in kidney development. http://purl.obolibrary.org/obo/GO_2000793 cell proliferation involved in heart valve development http://purl.obolibrary.org/obo/GO_0008283 cell population proliferation Any cell proliferation that is involved in heart valve development. http://purl.obolibrary.org/obo/GO_2000826 regulation of heart morphogenesis http://purl.obolibrary.org/obo/GO_2000027 regulation of animal organ morphogenesis Any process that modulates the frequency, rate or extent of heart morphogenesis. http://purl.obolibrary.org/obo/GO_2000858 regulation of aldosterone secretion http://purl.obolibrary.org/obo/GO_2000855 regulation of mineralocorticoid secretion Any process that modulates the frequency, rate or extent of aldosterone secretion. http://purl.obolibrary.org/obo/GO_2001141 regulation of RNA biosynthetic process http://purl.obolibrary.org/obo/GO_0051252 regulation of RNA metabolic process Any process that modulates the frequency, rate or extent of RNA biosynthetic process. http://purl.obolibrary.org/obo/GO_0019093 mitochondrial RNA localization http://purl.obolibrary.org/obo/GO_0006403 RNA localization Any process in which mitochondrial RNA is transported to, or maintained in, a specific location. http://purl.obolibrary.org/obo/GO_0019215 intermediate filament binding http://purl.obolibrary.org/obo/GO_0005488 binding Binding to an intermediate filament, a distinct elongated structure, characteristically 10 nm in diameter, that occurs in the cytoplasm of higher eukaryotic cells. Intermediate filaments form a fibrous system, composed of chemically heterogeneous subunits and involved in mechanically integrating the various components of the cytoplasmic space. http://purl.obolibrary.org/obo/GO_0019216 regulation of lipid metabolic process http://purl.obolibrary.org/obo/GO_0080090 regulation of primary metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving lipids. http://purl.obolibrary.org/obo/GO_0019226 transmission of nerve impulse http://purl.obolibrary.org/obo/GO_0050877 nervous system process The neurological system process in which a signal is transmitted through the nervous system by a combination of action potential propagation and synaptic transmission. http://purl.obolibrary.org/obo/GO_0019228 neuronal action potential http://purl.obolibrary.org/obo/GO_0001508 action potential An action potential that occurs in a neuron. http://purl.obolibrary.org/obo/GO_0019230 proprioception http://purl.obolibrary.org/obo/GO_0007600 sensory perception The series of events by which an organism senses the position, location, orientation, and movement of the body and its parts. Proprioception is mediated by proprioceptors, sensory nerve terminals found in muscles, tendons, and joint capsules, which give information concerning movements and position of the body. The receptors in the labyrinth are sometimes also considered proprioceptors. http://purl.obolibrary.org/obo/GO_0019233 sensory perception of pain http://purl.obolibrary.org/obo/GO_0007600 sensory perception The series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal. A painful stimulus is any physical or chemical event that has the potential to cause tissue damage (actual or perceived) and activates the nociceptive system. http://purl.obolibrary.org/obo/GO_0019336 phenol-containing compound catabolic process http://purl.obolibrary.org/obo/GO_0009056 catabolic process The chemical reactions and pathways resulting in the breakdown of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring. http://purl.obolibrary.org/obo/GO_0019377 glycolipid catabolic process http://purl.obolibrary.org/obo/GO_1901136 carbohydrate derivative catabolic process The chemical reactions and pathways resulting in the breakdown of glycolipid, a class of 1,2-di-O-acylglycerols joined at oxygen 3 by a glycosidic linkage to a carbohydrate part (usually a mono-, di- or tri-saccharide). http://purl.obolibrary.org/obo/GO_0019464 glycine decarboxylation via glycine cleavage system http://purl.obolibrary.org/obo/GO_0006546 glycine catabolic process The chemical reactions and pathways resulting in the breakdown of glycine by oxidative cleavage to carbon dioxide, ammonia, and a methylene group, mediated by enzymes of the glycine cleavage complex. http://purl.obolibrary.org/obo/GO_0019614 catechol-containing compound catabolic process http://purl.obolibrary.org/obo/GO_0019336 phenol-containing compound catabolic process The chemical reactions and pathways resulting in the breakdown of catechol-containing compounds. Catechol is a compound containing a pyrocatechol nucleus or substituent. http://purl.obolibrary.org/obo/GO_0019626 short-chain fatty acid catabolic process http://purl.obolibrary.org/obo/GO_0046459 short-chain fatty acid metabolic process The chemical reactions and pathways resulting in the breakdown of a short-chain fatty acid. A short-chain fatty acid has an aliphatic tail containing fewer than 6 carbons. http://purl.obolibrary.org/obo/GO_0019814 immunoglobulin complex http://purl.obolibrary.org/obo/GO_0032991 protein-containing complex A protein complex that in its canonical form is composed of two identical immunoglobulin heavy chains and two identical immunoglobulin light chains, held together by disulfide bonds and sometimes complexed with additional proteins. An immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph. http://purl.obolibrary.org/obo/GO_0019815 B cell receptor complex http://purl.obolibrary.org/obo/GO_0019814 immunoglobulin complex An immunoglobulin complex that is present in the plasma membrane of B cells and that in its canonical form is composed of two identical immunoglobulin heavy chains and two identical immunoglobulin light chains and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins. http://purl.obolibrary.org/obo/GO_0019825 oxygen binding http://purl.obolibrary.org/obo/GO_0036094 small molecule binding Binding to oxygen (O2). http://purl.obolibrary.org/obo/GO_0019896 axonal transport of mitochondrion http://purl.obolibrary.org/obo/GO_0047497 mitochondrion transport along microtubule The directed movement of mitochondria along microtubules in nerve cell axons. http://purl.obolibrary.org/obo/GO_0021501 prechordal plate formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The formation of the prechordal plate. The prechordal plate is a thickening of the endoderm at the cranial end of the primitive streak formed by the involution of Spemann's organizer cells. The prechordal plate and the notochord induce the formation of the neural plate from the overlying ectodermal cells. http://purl.obolibrary.org/obo/GO_0021508 floor plate formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The formation of a ventral region of glial cells in the neural tube that provides inductive signals for the specification of neuronal cell types. The floor plate is evident at the ventral midline by the neural fold stage. http://purl.obolibrary.org/obo/GO_0021509 roof plate formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The formation of a single row of glia at the dorsal midline of the developing neural tube. This region provides inductive signals for the specification of neuronal cell types and of the specification of neural crest cells. The cells comprising the roof plate are the precursors to radial glial cells. http://purl.obolibrary.org/obo/GO_0021510 spinal cord development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the spinal cord over time, from its formation to the mature structure. The spinal cord primarily conducts sensory and motor nerve impulses between the brain and the peripheral nervous tissues. http://purl.obolibrary.org/obo/GO_0021514 ventral spinal cord interneuron differentiation http://purl.obolibrary.org/obo/GO_0021953 central nervous system neuron differentiation The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of ventral spinal cord interneurons. Ventral spinal cord interneurons are cells located in the ventral portion of the spinal cord that transmit signals between sensory and motor neurons and are required for reflexive responses. Differentiation includes the processes involved in commitment of a cell to a specific fate. http://purl.obolibrary.org/obo/GO_0021515 cell differentiation in spinal cord http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the spinal cord. Differentiation includes the processes involved in commitment of a cell to a specific fate. http://purl.obolibrary.org/obo/GO_0021516 dorsal spinal cord development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the dorsal region of the spinal cord over time, from its formation to the mature structure. The dorsal region of the mature spinal cord contains neurons that process and relay sensory input. http://purl.obolibrary.org/obo/GO_0021517 ventral spinal cord development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the ventral region of the spinal cord over time, from its formation to the mature structure. The neurons of the ventral region of the mature spinal cord participate in motor output. http://purl.obolibrary.org/obo/GO_0021522 spinal cord motor neuron differentiation http://purl.obolibrary.org/obo/GO_0021953 central nervous system neuron differentiation The process in which neuroepithelial cells in the ventral neural tube acquire specialized structural and/or functional features of motor neurons. Motor neurons innervate an effector (muscle or glandular) tissue and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate. http://purl.obolibrary.org/obo/GO_0021523 somatic motor neuron differentiation http://purl.obolibrary.org/obo/GO_0021522 spinal cord motor neuron differentiation The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of somatic motor neurons. Somatic motor neurons innervate skeletal muscle targets and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate. http://purl.obolibrary.org/obo/GO_0021525 lateral motor column neuron differentiation http://purl.obolibrary.org/obo/GO_0021522 spinal cord motor neuron differentiation The process in which differentiating motor neurons in the neural tube acquire the specialized structural and/or functional features of lateral motor column neurons. Lateral motor column neurons are generated only on limb levels and send axons into the limb mesenchyme. Differentiation includes the processes involved in commitment of a cell to a specific fate. http://purl.obolibrary.org/obo/GO_0021531 spinal cord radial glial cell differentiation http://purl.obolibrary.org/obo/GO_0060019 radial glial cell differentiation The process in which neuroepithelial cells in the ventral neural tube acquire specialized structural and/or functional features of radial glial cells. Radial cell precursors differentiate into both neuronal cell types and mature radial glial cells. Mature radial glial cells regulate the axon growth and pathfinding processes that occur during white matter patterning of the developing spinal cord. Differentiation includes the processes involved in commitment of a cell to a specific fate. http://purl.obolibrary.org/obo/GO_0021532 neural tube patterning http://purl.obolibrary.org/obo/GO_0003002 regionalization The regionalization process that regulates the coordinated growth that establishes the non-random spatial arrangement of the neural tube. http://purl.obolibrary.org/obo/GO_0021533 cell differentiation in hindbrain http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mature cells of the hindbrain. Differentiation includes the processes involved in commitment of a cell to a specific fate. http://purl.obolibrary.org/obo/GO_0021534 cell proliferation in hindbrain http://purl.obolibrary.org/obo/GO_0061351 neural precursor cell proliferation The multiplication or reproduction of cells, resulting in the expansion of a cell population in the hindbrain. http://purl.obolibrary.org/obo/GO_0021535 cell migration in hindbrain http://purl.obolibrary.org/obo/GO_0016477 cell migration The orderly movement of a cell that will reside in the hindbrain. http://purl.obolibrary.org/obo/GO_0021536 diencephalon development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the diencephalon over time, from its formation to the mature structure. The diencephalon is the paired caudal parts of the prosencephalon from which the thalamus, hypothalamus, epithalamus and subthalamus are derived; these regions regulate autonomic, visceral and endocrine function, and process information directed to the cerebral cortex. http://purl.obolibrary.org/obo/GO_0021537 telencephalon development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the telencephalon over time, from its formation to the mature structure. The telencephalon is the paired anteriolateral division of the prosencephalon plus the lamina terminalis from which the olfactory lobes, cerebral cortex, and subcortical nuclei are derived. http://purl.obolibrary.org/obo/GO_0021538 epithalamus development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the epithalamus over time from its initial formation until its mature state. The epithalamus is the small dorsomedial area of the thalamus including the habenular nuclei and associated fiber bundles, the pineal body, and the epithelial roof of the third ventricle. http://purl.obolibrary.org/obo/GO_0021539 subthalamus development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the subthalamus over time, from its formation to the mature structure. The subthalamus is the anterior part of the diencephalon that lies between the thalamus, hypothalamus, and tegmentum of the mesencephalon, including subthalamic nucleus, zona incerta, the fields of Forel, and the nucleus of ansa lenticularis. http://purl.obolibrary.org/obo/GO_0021540 corpus callosum morphogenesis http://purl.obolibrary.org/obo/GO_0021952 central nervous system projection neuron axonogenesis The process in which the anatomical structures of the corpus callosum are generated and organized. The corpus callosum is a thick bundle of nerve fibers comprising a commissural plate connecting the two cerebral hemispheres. It consists of contralateral axon projections that provides communications between the right and left cerebral hemispheres. http://purl.obolibrary.org/obo/GO_0021541 ammon gyrus development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the ammon gyrus over time, from its formation to the mature structure. The ammon gyrus, often subdivided into the CA1 and CA3 regions, is one of the two interlocking gyri of the hippocampus that is rich in large pyramidal neurons. http://purl.obolibrary.org/obo/GO_0021542 dentate gyrus development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the dentate gyrus over time, from its formation to the mature structure. The dentate gyrus is one of two interlocking gyri of the hippocampus. It contains granule cells, which project to the pyramidal cells and interneurons of the CA3 region of the ammon gyrus. http://purl.obolibrary.org/obo/GO_0021543 pallium development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the pallium over time, from its formation to the mature structure. The pallium is the roof region of the telencephalon. http://purl.obolibrary.org/obo/GO_0021544 subpallium development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the subpallium over time, from its formation to the mature structure. The subpallium is the base region of the telencephalon. http://purl.obolibrary.org/obo/GO_0021545 cranial nerve development http://purl.obolibrary.org/obo/GO_0021675 nerve development The process whose specific outcome is the progression of the cranial nerves over time, from its formation to the mature structure. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions. http://purl.obolibrary.org/obo/GO_0021546 rhombomere development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the rhombomere over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. http://purl.obolibrary.org/obo/GO_0021547 midbrain-hindbrain boundary initiation http://purl.obolibrary.org/obo/GO_0003002 regionalization The regionalization process that gives rise to the midbrain-hindbrain boundary. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate. http://purl.obolibrary.org/obo/GO_0021548 pons development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the pons over time, from its formation to the mature structure. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum. http://purl.obolibrary.org/obo/GO_0021549 cerebellum development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the cerebellum over time, from its formation to the mature structure. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. In mice, the cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills. http://purl.obolibrary.org/obo/GO_0021550 medulla oblongata development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the medulla oblongata over time, from its formation to the mature structure. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate. http://purl.obolibrary.org/obo/GO_0021551 central nervous system morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structure of the central nervous system is generated and organized. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord. http://purl.obolibrary.org/obo/GO_0021553 olfactory nerve development http://purl.obolibrary.org/obo/GO_0021545 cranial nerve development The process whose specific outcome is the progression of the olfactory nerve over time, from its formation to the mature structure. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem. http://purl.obolibrary.org/obo/GO_0021554 optic nerve development http://purl.obolibrary.org/obo/GO_0021545 cranial nerve development The process whose specific outcome is the progression of the optic nerve over time, from its formation to the mature structure. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain. http://purl.obolibrary.org/obo/GO_0021555 midbrain-hindbrain boundary morphogenesis http://purl.obolibrary.org/obo/GO_0048598 embryonic morphogenesis The process in which the anatomical structure of the midbrain-hindbrain boundary is generated and organized. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate. http://purl.obolibrary.org/obo/GO_0021556 central nervous system formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process that gives rise to the central nervous system. This process pertains to the initial formation of a structure from unspecified parts. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain, spinal cord and spinal nerves. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord. http://purl.obolibrary.org/obo/GO_0021557 oculomotor nerve development http://purl.obolibrary.org/obo/GO_0021545 cranial nerve development The process whose specific outcome is the progression of the oculomotor nerve over time, from its formation to the mature structure. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle. http://purl.obolibrary.org/obo/GO_0021559 trigeminal nerve development http://purl.obolibrary.org/obo/GO_0021545 cranial nerve development The process whose specific outcome is the progression of the trigeminal nerve over time, from its formation to the mature structure. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae. http://purl.obolibrary.org/obo/GO_0021561 facial nerve development http://purl.obolibrary.org/obo/GO_0021545 cranial nerve development The process whose specific outcome is the progression of the facial nerve over time, from its formation to the mature structure. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial ophthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives off nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities. http://purl.obolibrary.org/obo/GO_0021562 vestibulocochlear nerve development http://purl.obolibrary.org/obo/GO_0021545 cranial nerve development The process whose specific outcome is the progression of the vestibulocochlear nerve over time, from its formation to the mature structure. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea. http://purl.obolibrary.org/obo/GO_0021563 glossopharyngeal nerve development http://purl.obolibrary.org/obo/GO_0021545 cranial nerve development Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion. http://purl.obolibrary.org/obo/GO_0021564 vagus nerve development http://purl.obolibrary.org/obo/GO_0021545 cranial nerve development The process whose specific outcome is the progression of the vagus nerve over time, from its formation to the mature structure. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis. http://purl.obolibrary.org/obo/GO_0021565 accessory nerve development http://purl.obolibrary.org/obo/GO_0021545 cranial nerve development The process whose specific outcome is the progression of the accessory nerve over time, from its formation to the mature structure. In mice, the spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve. http://purl.obolibrary.org/obo/GO_0021566 hypoglossal nerve development http://purl.obolibrary.org/obo/GO_0021545 cranial nerve development The process whose specific outcome is the progression of the hypoglossal nerve over time, from its formation to the mature structure. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue. http://purl.obolibrary.org/obo/GO_0021567 rhombomere 1 development http://purl.obolibrary.org/obo/GO_0021546 rhombomere development The process whose specific outcome is the progression of rhombomere 1 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order. http://purl.obolibrary.org/obo/GO_0021575 hindbrain morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structure of the hindbrain is generated and organized. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions. http://purl.obolibrary.org/obo/GO_0021576 hindbrain formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process that gives rise to the hindbrain. This process pertains to the initial formation of a structure from unspecified parts. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions. http://purl.obolibrary.org/obo/GO_0021578 hindbrain maturation http://purl.obolibrary.org/obo/GO_0071695 anatomical structure maturation A developmental process, independent of morphogenetic (shape) change, that is required for the hindbrain to attain its fully functional state. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions. http://purl.obolibrary.org/obo/GO_0021579 medulla oblongata morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structure of the medulla oblongata is generated and organized. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate. http://purl.obolibrary.org/obo/GO_0021580 medulla oblongata formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process that gives rise to the medulla oblongata. This process pertains to the initial formation of a structure from unspecified parts. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate. http://purl.obolibrary.org/obo/GO_0021582 medulla oblongata maturation http://purl.obolibrary.org/obo/GO_0071695 anatomical structure maturation A developmental process, independent of morphogenetic (shape) change, that is required for the medulla oblongata to attain its fully functional state. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate. http://purl.obolibrary.org/obo/GO_0021583 pons morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structure of the pons is generated and organized. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum. http://purl.obolibrary.org/obo/GO_0021584 pons formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process that gives rise to the pons. This process pertains to the initial formation of a structure from unspecified parts. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum. http://purl.obolibrary.org/obo/GO_0021586 pons maturation http://purl.obolibrary.org/obo/GO_0071695 anatomical structure maturation A developmental process, independent of morphogenetic (shape) change, that is required for the pons to attain its fully functional state. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum. http://purl.obolibrary.org/obo/GO_0021587 cerebellum morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structure of the cerebellum is generated and organized. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. The cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills. http://purl.obolibrary.org/obo/GO_0021588 cerebellum formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process that gives rise to the cerebellum. This process pertains to the initial formation of a structure from unspecified parts. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. The cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills. http://purl.obolibrary.org/obo/GO_0021590 cerebellum maturation http://purl.obolibrary.org/obo/GO_0071695 anatomical structure maturation A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellum to attain its fully functional state. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. The cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills. http://purl.obolibrary.org/obo/GO_0021591 ventricular system development http://purl.obolibrary.org/obo/GO_0048731 system development The process whose specific outcome is the progression of the brain ventricular system over time, from its formation to the mature structure. The brain ventricular system consists of four communicating cavities within the brain that are continuous with the central canal of the spinal cord. These cavities include two lateral ventricles, the third ventricle and the fourth ventricle. Cerebrospinal fluid fills the ventricles and is produced by the choroid plexus. http://purl.obolibrary.org/obo/GO_0021592 fourth ventricle development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the fourth ventricle over time, from its formation to the mature structure. The fourth ventricle is an irregularly shaped cavity in the rhombencephalon, between the medulla oblongata, the pons, and the isthmus in front, and the cerebellum behind. It is continuous with the central canal of the cord below and with the cerebral aqueduct above, and through its lateral and median apertures it communicates with the subarachnoid space. http://purl.obolibrary.org/obo/GO_0021593 rhombomere morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structure of the rhombomere is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. http://purl.obolibrary.org/obo/GO_0021594 rhombomere formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process that gives rise to the rhombomere. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. http://purl.obolibrary.org/obo/GO_0021602 cranial nerve morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structure of the cranial nerves are generated and organized. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions. http://purl.obolibrary.org/obo/GO_0021603 cranial nerve formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process that gives rise to the cranial nerves. This process pertains to the initial formation of a structure from unspecified parts. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions. http://purl.obolibrary.org/obo/GO_0021605 cranial nerve maturation http://purl.obolibrary.org/obo/GO_0021682 nerve maturation A developmental process, independent of morphogenetic (shape) change, that is required for a cranial nerve to attain its fully functional state. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions. http://purl.obolibrary.org/obo/GO_0021606 accessory nerve maturation http://purl.obolibrary.org/obo/GO_0021605 cranial nerve maturation A developmental process, independent of morphogenetic (shape) change, that is required for the accessory nerve to attain its fully functional state. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve. http://purl.obolibrary.org/obo/GO_0021607 accessory nerve morphogenesis http://purl.obolibrary.org/obo/GO_0021602 cranial nerve morphogenesis The process in which the anatomical structure of the accessory nerve is generated and organized. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve. http://purl.obolibrary.org/obo/GO_0021608 accessory nerve formation http://purl.obolibrary.org/obo/GO_0021603 cranial nerve formation The process that gives rise to the accessory nerve. This process pertains to the initial formation of a structure from unspecified parts. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve. http://purl.obolibrary.org/obo/GO_0021610 facial nerve morphogenesis http://purl.obolibrary.org/obo/GO_0021602 cranial nerve morphogenesis The process in which the anatomical structure of the facial nerve is generated and organized. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial ophthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities. http://purl.obolibrary.org/obo/GO_0021611 facial nerve formation http://purl.obolibrary.org/obo/GO_0021603 cranial nerve formation The process that gives rise to the facial nerve. This process pertains to the initial formation of a structure from unspecified parts. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial ophthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities. http://purl.obolibrary.org/obo/GO_0021613 facial nerve maturation http://purl.obolibrary.org/obo/GO_0021605 cranial nerve maturation A developmental process, independent of morphogenetic (shape) change, that is required for the facial nerve to attain its fully functional state. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial ophthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities. http://purl.obolibrary.org/obo/GO_0021614 glossopharyngeal nerve maturation http://purl.obolibrary.org/obo/GO_0021605 cranial nerve maturation A developmental process, independent of morphogenetic (shape) change, that is required for the glossopharyngeal nerve to attain its fully functional state. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion. http://purl.obolibrary.org/obo/GO_0021615 glossopharyngeal nerve morphogenesis http://purl.obolibrary.org/obo/GO_0021602 cranial nerve morphogenesis The process in which the anatomical structure of the glossopharyngeal nerve is generated and organized. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion. http://purl.obolibrary.org/obo/GO_0021616 glossopharyngeal nerve formation http://purl.obolibrary.org/obo/GO_0021603 cranial nerve formation The process that gives rise to the glossopharyngeal nerve. This process pertains to the initial formation of a structure from unspecified parts. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion. http://purl.obolibrary.org/obo/GO_0021618 hypoglossal nerve morphogenesis http://purl.obolibrary.org/obo/GO_0021602 cranial nerve morphogenesis The process in which the anatomical structure of the hypoglossal nerve is generated and organized. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue. http://purl.obolibrary.org/obo/GO_0021619 hypoglossal nerve maturation http://purl.obolibrary.org/obo/GO_0021605 cranial nerve maturation A developmental process, independent of morphogenetic (shape) change, that is required for the hypoglossal nerve to attain its fully functional state. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue. http://purl.obolibrary.org/obo/GO_0021620 hypoglossal nerve formation http://purl.obolibrary.org/obo/GO_0021603 cranial nerve formation The process that gives rise to the hypoglossal nerve. This process pertains to the initial formation of a structure from unspecified parts. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue. http://purl.obolibrary.org/obo/GO_0021622 oculomotor nerve morphogenesis http://purl.obolibrary.org/obo/GO_0021602 cranial nerve morphogenesis The process in which the anatomical structure of the oculomotor nerve is generated and organized. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle. http://purl.obolibrary.org/obo/GO_0021623 oculomotor nerve formation http://purl.obolibrary.org/obo/GO_0021603 cranial nerve formation The process that gives rise to the oculomotor nerve. This process pertains to the initial formation of a structure from unspecified parts. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle. http://purl.obolibrary.org/obo/GO_0021625 oculomotor nerve maturation http://purl.obolibrary.org/obo/GO_0021605 cranial nerve maturation A developmental process, independent of morphogenetic (shape) change, that is required for the oculomotor nerve to attain its fully functional state. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle. http://purl.obolibrary.org/obo/GO_0021626 central nervous system maturation http://purl.obolibrary.org/obo/GO_0071695 anatomical structure maturation A developmental process, independent of morphogenetic (shape) change, that is required for the central nervous system to attain its fully functional state. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord. http://purl.obolibrary.org/obo/GO_0021627 olfactory nerve morphogenesis http://purl.obolibrary.org/obo/GO_0021602 cranial nerve morphogenesis The process in which the anatomical structure of the olfactory nerve is generated and organized. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem. http://purl.obolibrary.org/obo/GO_0021628 olfactory nerve formation http://purl.obolibrary.org/obo/GO_0021603 cranial nerve formation The process that gives rise to the olfactory nerve. This process pertains to the initial formation of a structure from unspecified parts. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem. http://purl.obolibrary.org/obo/GO_0021630 olfactory nerve maturation http://purl.obolibrary.org/obo/GO_0021605 cranial nerve maturation A developmental process, independent of morphogenetic (shape) change, that is required for the olfactory nerve to attain its fully functional state. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem. http://purl.obolibrary.org/obo/GO_0021631 optic nerve morphogenesis http://purl.obolibrary.org/obo/GO_0021602 cranial nerve morphogenesis The process in which the anatomical structure of the optic nerve is generated and organized. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain. http://purl.obolibrary.org/obo/GO_0021632 optic nerve maturation http://purl.obolibrary.org/obo/GO_0021605 cranial nerve maturation A developmental process, independent of morphogenetic (shape) change, that is required for the optic nerve to attain its fully functional state. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain. http://purl.obolibrary.org/obo/GO_0021634 optic nerve formation http://purl.obolibrary.org/obo/GO_0021603 cranial nerve formation The process that gives rise to the optic nerve. This process pertains to the initial formation of a structure from unspecified parts. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain. http://purl.obolibrary.org/obo/GO_0021635 trigeminal nerve maturation http://purl.obolibrary.org/obo/GO_0021605 cranial nerve maturation A developmental process, independent of morphogenetic (shape) change, that is required for the trigeminal nerve to attain its fully functional state. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae. http://purl.obolibrary.org/obo/GO_0021636 trigeminal nerve morphogenesis http://purl.obolibrary.org/obo/GO_0021602 cranial nerve morphogenesis The process in which the anatomical structure of the trigeminal nerve is generated and organized. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae. http://purl.obolibrary.org/obo/GO_0021638 trigeminal nerve formation http://purl.obolibrary.org/obo/GO_0021603 cranial nerve formation The process that gives rise to the trigeminal nerve. This process pertains to the initial formation of a structure from unspecified parts. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae. http://purl.obolibrary.org/obo/GO_0021643 vagus nerve maturation http://purl.obolibrary.org/obo/GO_0021605 cranial nerve maturation A developmental process, independent of morphogenetic (shape) change, that is required for the vagus nerve to attain its fully functional state. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis. http://purl.obolibrary.org/obo/GO_0021644 vagus nerve morphogenesis http://purl.obolibrary.org/obo/GO_0021602 cranial nerve morphogenesis The process in which the anatomical structure of the vagus nerve is generated and organized. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis. http://purl.obolibrary.org/obo/GO_0021646 vagus nerve formation http://purl.obolibrary.org/obo/GO_0021603 cranial nerve formation The process that gives rise to the vagus nerve. This process pertains to the initial formation of a structure from unspecified parts. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis. http://purl.obolibrary.org/obo/GO_0021647 vestibulocochlear nerve maturation http://purl.obolibrary.org/obo/GO_0021605 cranial nerve maturation A developmental process, independent of morphogenetic (shape) change, that is required for the vestibulocochlear nerve to attain its fully functional state. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea. http://purl.obolibrary.org/obo/GO_0021648 vestibulocochlear nerve morphogenesis http://purl.obolibrary.org/obo/GO_0021602 cranial nerve morphogenesis The process in which the anatomical structure of the vestibulocochlear nerve is generated and organized. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea. http://purl.obolibrary.org/obo/GO_0021650 vestibulocochlear nerve formation http://purl.obolibrary.org/obo/GO_0021603 cranial nerve formation The process that gives rise to the vestibulocochlear nerve. This process pertains to the initial formation of a structure from unspecified parts. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea. http://purl.obolibrary.org/obo/GO_0021651 rhombomere 1 morphogenesis http://purl.obolibrary.org/obo/GO_0021593 rhombomere morphogenesis The process in which the anatomical structure of rhombomere 1 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order. http://purl.obolibrary.org/obo/GO_0021652 rhombomere 1 formation http://purl.obolibrary.org/obo/GO_0021594 rhombomere formation The process that gives rise to rhombomere 1. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order. http://purl.obolibrary.org/obo/GO_0021654 rhombomere boundary formation http://purl.obolibrary.org/obo/GO_0048859 formation of anatomical boundary The process that gives rise to a rhombomere boundary. This process pertains to the initial formation of a boundary delimiting a rhombomere. Rhombomeres are transverse segments of the developing rhombencephalon that are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order. http://purl.obolibrary.org/obo/GO_0021670 lateral ventricle development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the lateral ventricles over time, from the formation to the mature structure. The two lateral ventricles are a cavity in each of the cerebral hemispheres derived from the cavity of the embryonic neural tube. They are separated from each other by the septum pellucidum, and each communicates with the third ventricle by the foramen of Monro, through which also the choroid plexuses of the lateral ventricles become continuous with that of the third ventricle. http://purl.obolibrary.org/obo/GO_0021675 nerve development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of a nerve over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0021678 third ventricle development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the third ventricle over time, from its formation to the mature structure. The third ventricle is the narrow cleft inferior to the corpus callosum, within the diencephalon, between the paired thalami. Its floor is formed by the hypothalamus, its anterior wall by the lamina terminalis, and its roof by ependyma, and it communicates with the fourth ventricle by the cerebral aqueduct, and with the lateral ventricles by the interventricular foramina. http://purl.obolibrary.org/obo/GO_0021679 cerebellar molecular layer development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the cerebellar molecular layer nerve over time, from its formation to the mature structure. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells. http://purl.obolibrary.org/obo/GO_0021680 cerebellar Purkinje cell layer development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the cerebellar Purkinje cell layer over time, from its formation to the mature structure. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells. http://purl.obolibrary.org/obo/GO_0021681 cerebellar granular layer development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the cerebellar granule layer over time, from its formation to the mature structure. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer. http://purl.obolibrary.org/obo/GO_0021682 nerve maturation http://purl.obolibrary.org/obo/GO_0071695 anatomical structure maturation A developmental process, independent of morphogenetic (shape) change, that is required for a nerve to attain its fully functional state. http://purl.obolibrary.org/obo/GO_0021683 cerebellar granular layer morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structure of the cerebellar granular layer is generated and organized. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer. http://purl.obolibrary.org/obo/GO_0021684 cerebellar granular layer formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process that gives rise to the cerebellar granule layer. This process pertains to the initial formation of a structure from unspecified parts. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer. http://purl.obolibrary.org/obo/GO_0021686 cerebellar granular layer maturation http://purl.obolibrary.org/obo/GO_0071695 anatomical structure maturation A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar granular layer to attain its fully functional state. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer. http://purl.obolibrary.org/obo/GO_0021687 cerebellar molecular layer morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structure of the cerebellar molecular layer is generated and organized. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells. http://purl.obolibrary.org/obo/GO_0021688 cerebellar molecular layer formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process that gives rise to the cerebellar molecular layer. This process pertains to the initial formation of a structure from unspecified parts. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells. http://purl.obolibrary.org/obo/GO_0021690 cerebellar molecular layer maturation http://purl.obolibrary.org/obo/GO_0071695 anatomical structure maturation A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar molecular layer to attain its fully functional state. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells. http://purl.obolibrary.org/obo/GO_0021691 cerebellar Purkinje cell layer maturation http://purl.obolibrary.org/obo/GO_0071695 anatomical structure maturation A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar Purkinje cell layer to attain its fully functional state. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells. http://purl.obolibrary.org/obo/GO_0021692 cerebellar Purkinje cell layer morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structure of the cerebellar Purkinje cell layer is generated and organized. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells. http://purl.obolibrary.org/obo/GO_0021694 cerebellar Purkinje cell layer formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process that gives rise to the cerebellar Purkinje cell layer. This process pertains to the initial formation of a structure from unspecified parts. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells. http://purl.obolibrary.org/obo/GO_0021695 cerebellar cortex development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the cerebellar cortex over time, from its formation to the mature structure. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function. http://purl.obolibrary.org/obo/GO_0021696 cerebellar cortex morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structure of the cranial nerves are generated and organized. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function. http://purl.obolibrary.org/obo/GO_0021697 cerebellar cortex formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process that gives rise to the cerebellar cortex. This process pertains to the initial formation of a structure from unspecified parts. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function. http://purl.obolibrary.org/obo/GO_0021699 cerebellar cortex maturation http://purl.obolibrary.org/obo/GO_0071695 anatomical structure maturation A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar cortex to attain its fully functional state. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function. http://purl.obolibrary.org/obo/GO_0021701 cerebellar Golgi cell differentiation http://purl.obolibrary.org/obo/GO_0097154 GABAergic neuron differentiation The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar Golgi cell. Differentiation includes the processes involved in commitment of a neuroblast to a Golgi cell fate. A cerebellar Golgi cell is an inhibitory GABAergic interneuron found in the cerebellar cortex. http://purl.obolibrary.org/obo/GO_0021702 cerebellar Purkinje cell differentiation http://purl.obolibrary.org/obo/GO_0097154 GABAergic neuron differentiation The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar Purkinje cell. Differentiation includes the processes involved in commitment of a neuroblast to a Purkinje cell fate. A Purkinje cell is an inhibitory GABAergic neuron found in the cerebellar cortex that projects to the deep cerebellar nuclei and brain stem. http://purl.obolibrary.org/obo/GO_0021703 locus ceruleus development http://purl.obolibrary.org/obo/GO_0048857 neural nucleus development The process whose specific outcome is the progression of the locus ceruleus over time, from its formation to the mature structure. The locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic. http://purl.obolibrary.org/obo/GO_0021704 locus ceruleus morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structure of the locus ceruleus is generated and organized. In mice, the locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic. http://purl.obolibrary.org/obo/GO_0021705 locus ceruleus formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process that gives rise to the locus ceruleus. This process pertains to the initial formation of a structure from unspecified parts. In mice, the locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic. http://purl.obolibrary.org/obo/GO_0021706 locus ceruleus maturation http://purl.obolibrary.org/obo/GO_0071695 anatomical structure maturation A developmental process, independent of morphogenetic (shape) change, that is required for the locus ceruleus to attain its fully functional state. The locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic. http://purl.obolibrary.org/obo/GO_0021707 cerebellar granule cell differentiation http://purl.obolibrary.org/obo/GO_0021953 central nervous system neuron differentiation The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar granule cell. Differentiation includes the processes involved in commitment of a neuroblast to a granule cell fate. A granule cell is a glutamatergic interneuron found in the cerebellar cortex. http://purl.obolibrary.org/obo/GO_0021708 Lugaro cell differentiation http://purl.obolibrary.org/obo/GO_0097154 GABAergic neuron differentiation The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature Lugaro cell. Differentiation includes the processes involved in commitment of a neuroblast to a Lugaro cell fate. A Lugaro cell is an inhibitory GABAergic interneuron found in the cerebellar cortex. http://purl.obolibrary.org/obo/GO_0021710 cerebellar stellate cell differentiation http://purl.obolibrary.org/obo/GO_0097154 GABAergic neuron differentiation The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar stellate cell. Differentiation includes the processes involved in commitment of a neuroblast to a cerebellar stellate cell fate. A cerebellar stellate cell is an inhibitory GABAergic interneuron found in the cerebellar cortex. http://purl.obolibrary.org/obo/GO_0021718 superior olivary nucleus development http://purl.obolibrary.org/obo/GO_0048857 neural nucleus development The process whose specific outcome is the progression of the superior olivary nucleus over time, from its formation to the mature structure. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound. http://purl.obolibrary.org/obo/GO_0021719 superior olivary nucleus morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structure of the superior olivary nucleus is generated and organized. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound. http://purl.obolibrary.org/obo/GO_0021720 superior olivary nucleus formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process that gives rise to the superior olivary nucleus. This process pertains to the initial formation of a structure from unspecified parts. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound. http://purl.obolibrary.org/obo/GO_0021722 superior olivary nucleus maturation http://purl.obolibrary.org/obo/GO_0071695 anatomical structure maturation A developmental process, independent of morphogenetic (shape) change, that is required for the superior olivary nucleus to attain its fully functional state. The superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound. http://purl.obolibrary.org/obo/GO_0021732 midbrain-hindbrain boundary maturation http://purl.obolibrary.org/obo/GO_0071695 anatomical structure maturation A developmental process, independent of morphogenetic (shape) change, that is required for the midbrain-hindbrain boundary to attain its fully functional state. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate. http://purl.obolibrary.org/obo/GO_0021743 hypoglossal nucleus development http://purl.obolibrary.org/obo/GO_0048857 neural nucleus development The process whose specific outcome is the progression of the hypoglossal nucleus over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0021747 cochlear nucleus development http://purl.obolibrary.org/obo/GO_0048857 neural nucleus development The process whose specific outcome is the progression of the cochlear nucleus over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0021748 dorsal cochlear nucleus development http://purl.obolibrary.org/obo/GO_0021747 cochlear nucleus development The process whose specific outcome is the progression of the dorsal cochlear nucleus over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0021749 ventral cochlear nucleus development http://purl.obolibrary.org/obo/GO_0021747 cochlear nucleus development The process whose specific outcome is the progression of the ventral cochlear nucleus over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0021750 vestibular nucleus development http://purl.obolibrary.org/obo/GO_0048857 neural nucleus development The process whose specific outcome is the progression of the vestibular nucleus over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0021751 salivary nucleus development http://purl.obolibrary.org/obo/GO_0048857 neural nucleus development The process whose specific outcome is the progression of a salivary nucleus over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0021753 superior salivary nucleus development http://purl.obolibrary.org/obo/GO_0021751 salivary nucleus development The process whose specific outcome is the progression of the superior salivary nucleus over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0021754 facial nucleus development http://purl.obolibrary.org/obo/GO_0048857 neural nucleus development The process whose specific outcome is the progression of the facial nucleus over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0021755 eurydendroid cell differentiation http://purl.obolibrary.org/obo/GO_0021953 central nervous system neuron differentiation The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature eurydendroid cell. Differentiation includes the processes involved in commitment of a neuroblast to a eurydendroid cell fate. A eurydendroid cell is an efferent neuron found in the cerebellar cortex of teleosts. http://purl.obolibrary.org/obo/GO_0021756 striatum development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the striatum over time from its initial formation until its mature state. The striatum is a region of the forebrain consisting of the caudate nucleus, putamen and fundus striati. http://purl.obolibrary.org/obo/GO_0021757 caudate nucleus development http://purl.obolibrary.org/obo/GO_0048857 neural nucleus development The progression of the caudate nucleus over time from its initial formation until its mature state. The caudate nucleus is the C-shaped structures of the striatum containing input neurons involved with control of voluntary movement in the brain. http://purl.obolibrary.org/obo/GO_0021758 putamen development http://purl.obolibrary.org/obo/GO_0048857 neural nucleus development The progression of the putamen over time from its initial formation until its mature state. The putamen is the lens-shaped basal ganglion involved with control of voluntary movement in the brain. http://purl.obolibrary.org/obo/GO_0021759 globus pallidus development http://purl.obolibrary.org/obo/GO_0048857 neural nucleus development The progression of the globus pallidus over time from its initial formation until its mature state. The globus pallidus is one of the basal ganglia involved with control of voluntary movement in the brain. http://purl.obolibrary.org/obo/GO_0021761 limbic system development http://purl.obolibrary.org/obo/GO_0048731 system development The progression of the limbic system over time from its initial formation until its mature state. The limbic system is a collection of structures in the brain involved in emotion, motivation and emotional aspects of memory. http://purl.obolibrary.org/obo/GO_0021762 substantia nigra development http://purl.obolibrary.org/obo/GO_0048857 neural nucleus development The progression of the substantia nigra over time from its initial formation until its mature state. The substantia nigra is the layer of gray substance that separates the posterior parts of the cerebral peduncles (tegmentum mesencephali) from the anterior parts; it normally includes a posterior compact part with many pigmented cells (pars compacta) and an anterior reticular part whose cells contain little pigment (pars reticularis). http://purl.obolibrary.org/obo/GO_0021763 subthalamic nucleus development http://purl.obolibrary.org/obo/GO_0048857 neural nucleus development The progression of the subthalamic nucleus over time from its initial formation until its mature state. The subthalamic nucleus is the lens-shaped nucleus located in the ventral part of the subthalamus on the inner aspect of the internal capsule that is concerned with the integration of somatic motor function. http://purl.obolibrary.org/obo/GO_0021764 amygdala development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the amygdala over time from its initial formation until its mature state. The amygdala is an almond-shaped set of neurons in the medial temporal lobe of the brain that play a key role in processing emotions such as fear and pleasure. http://purl.obolibrary.org/obo/GO_0021766 hippocampus development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the hippocampus over time from its initial formation until its mature state. http://purl.obolibrary.org/obo/GO_0021767 mammillary body development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the mammillary body over time from its initial formation until its mature state. The mammillary body is a protrusion at the posterior end of the hypothalamus that contains hypothalamic nuclei. http://purl.obolibrary.org/obo/GO_0021768 nucleus accumbens development http://purl.obolibrary.org/obo/GO_0048857 neural nucleus development The progression of the nucleus accumbens over time from its initial formation until its mature state. The nucleus accumbens is a collection of pleomorphic cells in the caudal part of the anterior horn of the lateral ventricle, in the region of the olfactory tubercle, lying between the head of the caudate nucleus and the anterior perforated substance. It is part of the ventral striatum, a composite structure considered part of the basal ganglia. http://purl.obolibrary.org/obo/GO_0021771 lateral geniculate nucleus development http://purl.obolibrary.org/obo/GO_0048857 neural nucleus development The progression of the lateral geniculate nucleus over time from its initial formation until its mature state. The lateral geniculate nucleus is the primary processor of visual information received from the retina. http://purl.obolibrary.org/obo/GO_0021772 olfactory bulb development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the olfactory bulb over time from its initial formation until its mature state. The olfactory bulb coordinates neuronal signaling involved in the perception of smell. It receives input from the sensory neurons and outputs to the olfactory cortex. http://purl.obolibrary.org/obo/GO_0021773 striatal medium spiny neuron differentiation http://purl.obolibrary.org/obo/GO_0097154 GABAergic neuron differentiation The process in which a relatively unspecialized cell acquires specialized features of a medium spiny neuron residing in the striatum. http://purl.obolibrary.org/obo/GO_0021783 preganglionic parasympathetic fiber development http://purl.obolibrary.org/obo/GO_0048731 system development The process whose specific outcome is the progression of a preganglionic parasympathetic fiber over time, from its formation to the mature structure. A preganglionic parasympathetic fiber is a cholinergic axonal fiber projecting from the CNS to a parasympathetic ganglion. http://purl.obolibrary.org/obo/GO_0021794 thalamus development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process in which the thalamus changes over time, from its initial formation to its mature state. http://purl.obolibrary.org/obo/GO_0021795 cerebral cortex cell migration http://purl.obolibrary.org/obo/GO_0022029 telencephalon cell migration The orderly movement of cells from one site to another in the cerebral cortex. http://purl.obolibrary.org/obo/GO_0021799 cerebral cortex radially oriented cell migration http://purl.obolibrary.org/obo/GO_0021795 cerebral cortex cell migration The migration of cells in the developing cerebral cortex in which cells move from the ventricular and/or subventricular zone toward the surface of the brain. http://purl.obolibrary.org/obo/GO_0021801 cerebral cortex radial glia-guided migration http://purl.obolibrary.org/obo/GO_0022030 telencephalon glial cell migration The radial migration of neuronal or glial precursor cells along radial glial cells during the development of the cerebral cortex. http://purl.obolibrary.org/obo/GO_0021814 cell motility involved in cerebral cortex radial glia guided migration http://purl.obolibrary.org/obo/GO_0048870 cell motility The movement of a cell along the process of a radial glial cell involved in cerebral cortex glial-mediated radial migration. http://purl.obolibrary.org/obo/GO_0021815 modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration http://purl.obolibrary.org/obo/GO_0000226 microtubule cytoskeleton organization Rearrangements of the microtubule cytoskeleton that contribute to the movement of cells along radial glial cells as a component of the process of cerebral cortex glial-mediated radial migration. http://purl.obolibrary.org/obo/GO_0021819 layer formation in cerebral cortex http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The detachment of cells from radial glial fibers at the appropriate time when they cease to migrate and form distinct layer in the cerebral cortex. http://purl.obolibrary.org/obo/GO_0021822 negative regulation of cell motility involved in cerebral cortex radial glia guided migration http://purl.obolibrary.org/obo/GO_1903976 negative regulation of glial cell migration The intracellular signaling pathway that results in the cessation of cell movement involved in lamination of the cerebral cortex. http://purl.obolibrary.org/obo/GO_0021826 substrate-independent telencephalic tangential migration http://purl.obolibrary.org/obo/GO_0022029 telencephalon cell migration The process where neuronal precursors migrate tangentially in the telencephalon, primarily guided by interactions that do not require cell-cell contact. http://purl.obolibrary.org/obo/GO_0021830 interneuron migration from the subpallium to the cortex http://purl.obolibrary.org/obo/GO_0021843 substrate-independent telencephalic tangential interneuron migration The directed movement of interneurons from the subpallium to the cortex during forebrain development. http://purl.obolibrary.org/obo/GO_0021843 substrate-independent telencephalic tangential interneuron migration http://purl.obolibrary.org/obo/GO_0021826 substrate-independent telencephalic tangential migration The directional movement of tangentially migrating interneurons that are not guided by attaching to extracellular substrates. http://purl.obolibrary.org/obo/GO_0021846 cell proliferation in forebrain http://purl.obolibrary.org/obo/GO_0061351 neural precursor cell proliferation The creation of greater cell numbers in the forebrain due to cell division of progenitor cells. http://purl.obolibrary.org/obo/GO_0021848 neuroblast division in subpallium http://purl.obolibrary.org/obo/GO_0055057 neuroblast division The division of neuroblasts in the subpallium area of the forebrain. The interneuron precursors that these cells give rise to include GABAergic interneurons and will migrate tangentially. http://purl.obolibrary.org/obo/GO_0021852 pyramidal neuron migration to cerebral cortex http://purl.obolibrary.org/obo/GO_0140650 radial glia-guided pyramidal neuron migration The migration of a pyramidal neuron precursor from the ventricular zone to the correct layer of the cerebral cortex. http://purl.obolibrary.org/obo/GO_0021853 cerebral cortex GABAergic interneuron migration http://purl.obolibrary.org/obo/GO_1904936 interneuron migration The migration of GABAergic interneuron precursors from the subpallium to the cerebral cortex. http://purl.obolibrary.org/obo/GO_0021854 hypothalamus development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the hypothalamus region of the forebrain, from its initial formation to its mature state. http://purl.obolibrary.org/obo/GO_0021859 pyramidal neuron differentiation http://purl.obolibrary.org/obo/GO_0021953 central nervous system neuron differentiation The process in which a neuroblast or one of its progeny commits to a pyramidal neuron fate, migrates from the ventricular zone to the appropriate layer in the cortex and develops into a mature neuron. http://purl.obolibrary.org/obo/GO_0021860 pyramidal neuron development http://purl.obolibrary.org/obo/GO_0021884 forebrain neuron development The progression of a pyramidal neuron from its initial formation to its mature state. http://purl.obolibrary.org/obo/GO_0021861 forebrain radial glial cell differentiation http://purl.obolibrary.org/obo/GO_0060019 radial glial cell differentiation The process in which neuroepithelial cells of the neural tube give rise to radial glial cells, specialized bipotential progenitors cells of the forebrain. Differentiation includes the processes involved in commitment of a cell to a specific fate. http://purl.obolibrary.org/obo/GO_0021863 forebrain neuroblast differentiation http://purl.obolibrary.org/obo/GO_0014016 neuroblast differentiation The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of basal progenitor cells, neuroblasts that lose their contacts with the ventricular surface. Differentiation includes the processes involved in commitment of a cell to a specific fate. http://purl.obolibrary.org/obo/GO_0021870 Cajal-Retzius cell differentiation http://purl.obolibrary.org/obo/GO_0021895 cerebral cortex neuron differentiation The process in which a neuroblast acquires specialized structural and/or functional features of a Cajal-Retzius cell, one of a transient population of pioneering neurons in the cerebral cortex. These cells are slender bipolar cells of the developing marginal zone. One feature of these cells in mammals is that they express the Reelin gene. http://purl.obolibrary.org/obo/GO_0021872 forebrain generation of neurons http://purl.obolibrary.org/obo/GO_0048699 generation of neurons The process in which nerve cells are generated in the forebrain. This includes the production of neuroblasts from and their differentiation into neurons. http://purl.obolibrary.org/obo/GO_0021879 forebrain neuron differentiation http://purl.obolibrary.org/obo/GO_0021953 central nervous system neuron differentiation The process in which a relatively unspecialized cell acquires specialized features of a neuron that will reside in the forebrain. http://purl.obolibrary.org/obo/GO_0021884 forebrain neuron development http://purl.obolibrary.org/obo/GO_0021954 central nervous system neuron development The process whose specific outcome is the progression of a neuron that resides in the forebrain, from its initial commitment to its fate, to the fully functional differentiated cell. http://purl.obolibrary.org/obo/GO_0021885 forebrain cell migration http://purl.obolibrary.org/obo/GO_0016477 cell migration The orderly movement of a cell from one site to another at least one of which is located in the forebrain. http://purl.obolibrary.org/obo/GO_0021889 olfactory bulb interneuron differentiation http://purl.obolibrary.org/obo/GO_0021879 forebrain neuron differentiation The process in which a neuroblast acquires specialized features of an interneuron residing in the olfactory bulb. http://purl.obolibrary.org/obo/GO_0021891 olfactory bulb interneuron development http://purl.obolibrary.org/obo/GO_0021884 forebrain neuron development The process whose specific outcome is the progression of an interneuron residing in the olfactory bulb, from its initial commitment, to the fully functional differentiated cell. http://purl.obolibrary.org/obo/GO_0021892 cerebral cortex GABAergic interneuron differentiation http://purl.obolibrary.org/obo/GO_0097154 GABAergic neuron differentiation The process in which a relatively unspecialized cell acquires specialized features of a GABAergic interneuron residing in the cerebral cortex. http://purl.obolibrary.org/obo/GO_0021894 cerebral cortex GABAergic interneuron development http://purl.obolibrary.org/obo/GO_0021884 forebrain neuron development The process whose specific outcome is the progression of a cerebral cortex GABAergic interneuron over time, from initial commitment to its fate, to the fully functional differentiated cell. http://purl.obolibrary.org/obo/GO_0021895 cerebral cortex neuron differentiation http://purl.obolibrary.org/obo/GO_0021879 forebrain neuron differentiation The process in which a relatively unspecialized cell acquires specialized features of a neuron residing in the cerebral cortex. http://purl.obolibrary.org/obo/GO_0021896 forebrain astrocyte differentiation http://purl.obolibrary.org/obo/GO_0048708 astrocyte differentiation The process in which a relatively unspecialized cell acquires the specialized features of an astrocyte residing in the forebrain. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function. http://purl.obolibrary.org/obo/GO_0021897 forebrain astrocyte development http://purl.obolibrary.org/obo/GO_0014002 astrocyte development The process aimed at the progression of an astrocyte that resides in the forebrain, from initial commitment of the cell to its fate, to the fully functional differentiated cell. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function. http://purl.obolibrary.org/obo/GO_0021903 rostrocaudal neural tube patterning http://purl.obolibrary.org/obo/GO_0009952 anterior/posterior pattern specification The process in which the neural tube is divided into specific regions along the rostrocaudal axis. http://purl.obolibrary.org/obo/GO_0021905 forebrain-midbrain boundary formation http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the creation of the forebrain-midbrain boundary. http://purl.obolibrary.org/obo/GO_0021906 hindbrain-spinal cord boundary formation http://purl.obolibrary.org/obo/GO_0048859 formation of anatomical boundary The process whose specific outcome is the formation of the hindbrain-spinal cord boundary. http://purl.obolibrary.org/obo/GO_0021921 regulation of cell proliferation in dorsal spinal cord http://purl.obolibrary.org/obo/GO_2000177 regulation of neural precursor cell proliferation The process that modulates the frequency, rate or extent of cell proliferation in the dorsal spinal cord. http://purl.obolibrary.org/obo/GO_0021952 central nervous system projection neuron axonogenesis http://purl.obolibrary.org/obo/GO_0021955 central nervous system neuron axonogenesis Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body towards target cells in a different central nervous system region. http://purl.obolibrary.org/obo/GO_0021953 central nervous system neuron differentiation http://purl.obolibrary.org/obo/GO_0030182 neuron differentiation The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the central nervous system. http://purl.obolibrary.org/obo/GO_0021954 central nervous system neuron development http://purl.obolibrary.org/obo/GO_0048666 neuron development The process whose specific outcome is the progression of a neuron whose cell body is located in the central nervous system, from initial commitment of the cell to a neuronal fate, to the fully functional differentiated neuron. http://purl.obolibrary.org/obo/GO_0021955 central nervous system neuron axonogenesis http://purl.obolibrary.org/obo/GO_0007409 axonogenesis Generation of a long process from a neuron whose cell body resides in the central nervous system. The process carries efferent (outgoing) action potentials from the cell body towards target cells. http://purl.obolibrary.org/obo/GO_0021957 corticospinal tract morphogenesis http://purl.obolibrary.org/obo/GO_0021952 central nervous system projection neuron axonogenesis Generation of a long process of a pyramidal cell, that carries efferent (outgoing) action potentials from the cell body in cerebral cortex layer V towards target cells in the gray matter of the spinal cord. This axonal process is a member of those that make up the corticospinal tract. http://purl.obolibrary.org/obo/GO_0021961 posterior commissure morphogenesis http://purl.obolibrary.org/obo/GO_0021952 central nervous system projection neuron axonogenesis Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the midbrain towards target cells in the diencephalon. http://purl.obolibrary.org/obo/GO_0021964 rubrospinal tract morphogenesis http://purl.obolibrary.org/obo/GO_0021952 central nervous system projection neuron axonogenesis Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the red nucleus of the midbrain towards target cells in the spinal cord. http://purl.obolibrary.org/obo/GO_0021982 pineal gland development http://purl.obolibrary.org/obo/GO_0048732 gland development The progression of the pineal gland over time from its initial formation until its mature state. The pineal gland is an endocrine gland that secretes melatonin and is involved in circadian rhythms. http://purl.obolibrary.org/obo/GO_0021983 pituitary gland development http://purl.obolibrary.org/obo/GO_0048732 gland development The progression of the pituitary gland over time from its initial formation until its mature state. The pituitary gland is an endocrine gland that secretes hormones that regulate many other glands. http://purl.obolibrary.org/obo/GO_0021984 adenohypophysis development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the adenohypophysis over time from its initial formation until its mature state. The adenohypophysis is the anterior part of the pituitary. It secretes a variety of hormones and its function is regulated by the hypothalamus. http://purl.obolibrary.org/obo/GO_0021985 neurohypophysis development http://purl.obolibrary.org/obo/GO_0048732 gland development The progression of the neurohypophysis over time from its initial formation until its mature state. The neurohypophysis is the part of the pituitary gland that secretes hormones involved in blood pressure regulation. http://purl.obolibrary.org/obo/GO_0021987 cerebral cortex development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the cerebral cortex over time from its initial formation until its mature state. The cerebral cortex is the outer layered region of the telencephalon. http://purl.obolibrary.org/obo/GO_0021988 olfactory lobe development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the olfactory lobe over time from its initial formation until its mature state. The olfactory lobe is the area of the brain that process the neural inputs for the sense of smell. http://purl.obolibrary.org/obo/GO_0021989 olfactory cortex development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the olfactory cortex over time from its initial formation until its mature state. The olfactory cortex is involved in the perception of smell. It receives input from the olfactory bulb and is responsible for the identification of odors. http://purl.obolibrary.org/obo/GO_0021990 neural plate formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The formation of the flat, thickened layer of ectodermal cells known as the neural plate. The underlying dorsal mesoderm signals the ectodermal cells above it to elongate into columnar neural plate cells. The neural plate subsequently develops into the neural tube, which gives rise to the central nervous system. http://purl.obolibrary.org/obo/GO_0021999 neural plate anterior/posterior regionalization http://purl.obolibrary.org/obo/GO_0060897 neural plate regionalization The process that regulates the coordinated growth and differentiation that establishes the non-random anterior-posterior spatial arrangement of the neural plate. http://purl.obolibrary.org/obo/GO_0022006 zona limitans intrathalamica formation http://purl.obolibrary.org/obo/GO_0048859 formation of anatomical boundary The formation of the narrow stripe of cells that lies between the prospective dorsal and ventral thalami. This boundary contains signals that pattern the prethalamic and thalamic territories of the future mid-diencephalon. http://purl.obolibrary.org/obo/GO_0022008 neurogenesis http://purl.obolibrary.org/obo/GO_0030154 cell differentiation Generation of cells within the nervous system. http://purl.obolibrary.org/obo/GO_0022009 central nervous system vasculogenesis http://purl.obolibrary.org/obo/GO_0001570 vasculogenesis The differentiation of endothelial cells from progenitor cells during blood vessel development, and the de novo formation of blood vessels and tubes in the central nervous system. The capillary endothelial cells in the brain are specialized to form the blood-brain barrier. http://purl.obolibrary.org/obo/GO_0022010 central nervous system myelination http://purl.obolibrary.org/obo/GO_0042552 myelination The process in which neuronal axons and dendrites become coated with a segmented lipid-rich sheath (myelin) to enable faster and more energetically efficient conduction of electrical impulses. The sheath is formed by the cell membranes of oligodendrocytes in the central nervous system. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier. http://purl.obolibrary.org/obo/GO_0022011 myelination in peripheral nervous system http://purl.obolibrary.org/obo/GO_0042552 myelination The process in which neuronal axons and dendrites become coated with a segmented lipid-rich sheath (myelin) to enable faster and more energetically efficient conduction of electrical impulses. The sheath is formed by the cell membranes of Schwann cells in the peripheral nervous system. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier. http://purl.obolibrary.org/obo/GO_0022012 subpallium cell proliferation in forebrain http://purl.obolibrary.org/obo/GO_0021846 cell proliferation in forebrain The multiplication or reproduction of subpallium cells in the forebrain, resulting in the expansion of a cell population. http://purl.obolibrary.org/obo/GO_0022029 telencephalon cell migration http://purl.obolibrary.org/obo/GO_0021885 forebrain cell migration The orderly movement of a cell from one site to another at least one of which is located in the telencephalon. http://purl.obolibrary.org/obo/GO_0022030 telencephalon glial cell migration http://purl.obolibrary.org/obo/GO_0008347 glial cell migration The orderly movement of glial cells through the telencephalon. http://purl.obolibrary.org/obo/GO_0022031 telencephalon astrocyte cell migration http://purl.obolibrary.org/obo/GO_0043615 astrocyte cell migration The orderly movement of an astrocyte cell through the telencephalon. http://purl.obolibrary.org/obo/GO_0022032 telencephalon oligodendrocyte cell migration http://purl.obolibrary.org/obo/GO_0022030 telencephalon glial cell migration The multiplication or reproduction of telencephalon oligodendrocyte cells, resulting in the expansion of a cell population. http://purl.obolibrary.org/obo/GO_0022033 telencephalon microglial cell migration http://purl.obolibrary.org/obo/GO_0022030 telencephalon glial cell migration The orderly movement of microglial cells through the telencephalon. http://purl.obolibrary.org/obo/GO_0022035 rhombomere cell migration http://purl.obolibrary.org/obo/GO_0021535 cell migration in hindbrain The movement of a cell within a rhombomere. This process is known to occur as an early step in the generation of anatomical structure from a rhombomere. http://purl.obolibrary.org/obo/GO_0022037 metencephalon development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the metencephalon over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0022038 corpus callosum development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the corpus callosum over time, from its formation to the mature structure. The corpus callosum is a thick bundle of nerve fibers comprising a commissural plate connecting the two cerebral hemispheres. It consists of contralateral axon projections that provide communication between the right and left cerebral hemispheres. http://purl.obolibrary.org/obo/GO_0022407 regulation of cell-cell adhesion http://purl.obolibrary.org/obo/GO_0030155 regulation of cell adhesion Any process that modulates the frequency, rate or extent of attachment of a cell to another cell. http://purl.obolibrary.org/obo/GO_0022408 negative regulation of cell-cell adhesion http://purl.obolibrary.org/obo/GO_0022407 regulation of cell-cell adhesion Any process that stops, prevents or reduces the rate or extent of cell adhesion to another cell. http://purl.obolibrary.org/obo/GO_0022409 positive regulation of cell-cell adhesion http://purl.obolibrary.org/obo/GO_0045785 positive regulation of cell adhesion Any process that activates or increases the rate or extent of cell adhesion to another cell. http://purl.obolibrary.org/obo/GO_0022605 mammalian oogenesis stage http://purl.obolibrary.org/obo/GO_0048609 multicellular organismal reproductive process A reproductive process that is a step in the formation and maturation of an ovum or female gamete from a primordial female germ cell. http://purl.obolibrary.org/obo/GO_0022613 ribonucleoprotein complex biogenesis http://purl.obolibrary.org/obo/GO_0044085 cellular component biogenesis A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a complex containing RNA and proteins. Includes the biosynthesis of the constituent RNA and protein molecules, and those macromolecular modifications that are involved in synthesis or assembly of the ribonucleoprotein complex. http://purl.obolibrary.org/obo/GO_0022835 transmitter-gated channel activity http://purl.obolibrary.org/obo/GO_0022834 ligand-gated channel activity Enables the transmembrane transfer of a solute by a channel that opens when a specific neurotransmitter has been bound by the channel complex or one of its constituent parts. http://purl.obolibrary.org/obo/GO_0022836 gated channel activity http://purl.obolibrary.org/obo/GO_0015267 channel activity Enables the transmembrane transfer of a solute by a channel that opens in response to a specific stimulus. http://purl.obolibrary.org/obo/GO_0022849 glutamate-gated calcium ion channel activity http://purl.obolibrary.org/obo/GO_0099604 ligand-gated calcium channel activity Enables the transmembrane transfer of a calcium ion by a channel that opens when glutamate has been bound by the channel complex or one of its constituent parts. http://purl.obolibrary.org/obo/GO_0022898 regulation of transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0065009 regulation of molecular function Any process that modulates the frequency, rate or extent of transmembrane transporter activity. http://purl.obolibrary.org/obo/GO_0023019 signal transduction involved in regulation of gene expression http://purl.obolibrary.org/obo/GO_0007165 signal transduction Any process that modulates the frequency, rate or extent of gene expression as a consequence of a process in which a signal is released and/or conveyed from one location to another. http://purl.obolibrary.org/obo/GO_0023023 MHC protein complex binding http://purl.obolibrary.org/obo/GO_0044877 protein-containing complex binding Binding to a major histocompatibility complex. http://purl.obolibrary.org/obo/GO_0023026 MHC class II protein complex binding http://purl.obolibrary.org/obo/GO_0023023 MHC protein complex binding Binding to a class II major histocompatibility complex. http://purl.obolibrary.org/obo/GO_0023029 MHC class Ib protein binding http://purl.obolibrary.org/obo/GO_0042287 MHC protein binding Binding to a major histocompatibility complex class Ib molecules. http://purl.obolibrary.org/obo/GO_0023052 signaling http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process The entirety of a process in which information is transmitted within a biological system. This process begins with an active signal and ends when a cellular response has been triggered. http://purl.obolibrary.org/obo/GO_0023061 signal release http://purl.obolibrary.org/obo/GO_0032940 secretion by cell The process in which a signal is secreted or discharged into the extracellular medium from a cellular source. http://purl.obolibrary.org/obo/GO_0030016 myofibril http://purl.obolibrary.org/obo/GO_0043292 contractile muscle fiber The contractile element of skeletal and cardiac muscle; a long, highly organized bundle of actin, myosin, and other proteins that contracts by a sliding filament mechanism. http://purl.obolibrary.org/obo/GO_0030029 actin filament-based process http://purl.obolibrary.org/obo/GO_0009987 cellular process Any cellular process that depends upon or alters the actin cytoskeleton, that part of the cytoskeleton comprising actin filaments and their associated proteins. http://purl.obolibrary.org/obo/GO_0030030 cell projection organization http://purl.obolibrary.org/obo/GO_0016043 cellular component organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon. http://purl.obolibrary.org/obo/GO_0030033 microvillus assembly http://purl.obolibrary.org/obo/GO_0120031 plasma membrane bounded cell projection assembly Formation of a microvillus, a thin cylindrical membrane-covered projection on the surface of a cell. http://purl.obolibrary.org/obo/GO_0030048 actin filament-based movement http://purl.obolibrary.org/obo/GO_0030029 actin filament-based process Movement of organelles or other particles along actin filaments, or sliding of actin filaments past each other, mediated by motor proteins. http://purl.obolibrary.org/obo/GO_0030050 vesicle transport along actin filament http://purl.obolibrary.org/obo/GO_0099518 vesicle cytoskeletal trafficking Movement of a vesicle along an actin filament, mediated by motor proteins. http://purl.obolibrary.org/obo/GO_0030057 desmosome http://purl.obolibrary.org/obo/GO_0005911 cell-cell junction A cell-cell junction in which: on the cytoplasmic surface of each interacting plasma membrane is a dense plaque composed of a mixture of intracellular anchor proteins; a bundle of keratin intermediate filaments is attached to the surface of each plaque; transmembrane adhesion proteins of the cadherin family bind to the plaques and interact through their extracellular domains to hold the adjacent membranes together by a Ca2+-dependent mechanism. http://purl.obolibrary.org/obo/GO_0030070 insulin processing http://purl.obolibrary.org/obo/GO_1901142 insulin metabolic process The formation of mature insulin by proteolysis of the precursor preproinsulin. The signal sequence is first cleaved from preproinsulin to form proinsulin; proinsulin is then cleaved to release the C peptide, leaving the A and B chains of mature insulin linked by disulfide bridges. http://purl.obolibrary.org/obo/GO_0030072 peptide hormone secretion http://purl.obolibrary.org/obo/GO_0046879 hormone secretion The regulated release of a peptide hormone from a cell. http://purl.obolibrary.org/obo/GO_0030073 insulin secretion http://purl.obolibrary.org/obo/GO_0030072 peptide hormone secretion The regulated release of proinsulin from secretory granules accompanied by cleavage of proinsulin to form mature insulin. In vertebrates, insulin is secreted from B granules in the B cells of the vertebrate pancreas and from insulin-producing cells in insects. http://purl.obolibrary.org/obo/GO_0030100 regulation of endocytosis http://purl.obolibrary.org/obo/GO_0060627 regulation of vesicle-mediated transport Any process that modulates the frequency, rate or extent of endocytosis. http://purl.obolibrary.org/obo/GO_0030133 transport vesicle http://purl.obolibrary.org/obo/GO_0031410 cytoplasmic vesicle Any of the vesicles of the constitutive secretory pathway, which carry cargo from the endoplasmic reticulum to the Golgi, between Golgi cisternae, from the Golgi to the ER (retrograde transport) or to destinations within or outside the cell. http://purl.obolibrary.org/obo/GO_0030136 clathrin-coated vesicle http://purl.obolibrary.org/obo/GO_0030135 coated vesicle A vesicle with a coat formed of clathrin connected to the membrane via one of the clathrin adaptor complexes. http://purl.obolibrary.org/obo/GO_0030150 protein import into mitochondrial matrix http://purl.obolibrary.org/obo/GO_0071806 protein transmembrane transport The import of proteins across the outer and inner mitochondrial membranes into the matrix. Unfolded proteins enter the mitochondrial matrix with a chaperone protein; the information required to target the precursor protein from the cytosol to the mitochondrial matrix is contained within its N-terminal matrix-targeting sequence. Translocation of precursors to the matrix occurs at the rare sites where the outer and inner membranes are close together. http://purl.obolibrary.org/obo/GO_0030162 regulation of proteolysis http://purl.obolibrary.org/obo/GO_0051246 regulation of protein metabolic process Any process that modulates the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein. http://purl.obolibrary.org/obo/GO_0030167 proteoglycan catabolic process http://purl.obolibrary.org/obo/GO_0006516 glycoprotein catabolic process The chemical reactions and pathways resulting in the breakdown of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans. http://purl.obolibrary.org/obo/GO_0030171 voltage-gated proton channel activity http://purl.obolibrary.org/obo/GO_0015252 proton channel activity Enables the transmembrane transfer of a proton by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. http://purl.obolibrary.org/obo/GO_0030184 nitric oxide transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity Enables the transfer of nitric oxide, nitrogen monoxide, from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0030185 nitric oxide transport http://purl.obolibrary.org/obo/GO_0071705 nitrogen compound transport The directed movement of nitric oxide, nitrogen monoxide, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0030186 melatonin metabolic process http://purl.obolibrary.org/obo/GO_0042445 hormone metabolic process The chemical reactions and pathways involving melatonin (N-acetyl-5-methoxytryptamine). http://purl.obolibrary.org/obo/GO_0030187 melatonin biosynthetic process http://purl.obolibrary.org/obo/GO_0042435 indole-containing compound biosynthetic process The chemical reactions and pathways resulting in the formation of melatonin (N-acetyl-5-methoxytryptamine). http://purl.obolibrary.org/obo/GO_0030199 collagen fibril organization http://purl.obolibrary.org/obo/GO_0030198 extracellular matrix organization Any process that determines the size and arrangement of collagen fibrils within an extracellular matrix. http://purl.obolibrary.org/obo/GO_0030202 heparin proteoglycan metabolic process http://purl.obolibrary.org/obo/GO_0006029 proteoglycan metabolic process The chemical reactions and pathways involving heparin proteoglycans, which consist of a core protein linked to a heparin glycosaminoglycan. The heparin chain is composed of the repeating disaccharide unit beta-(1,4)-N-acetyl-D-glucosamine-alpha-(1,4)-hexuronic acid, the former being either sulfated or deacetylated on its amino group as well as sulfated on one of its hydroxyl groups, and the latter being e a mixture of sulfated and nonsulfated D-glucuronic and L-iduronic acids. Heparin is similar to heparan sulfate but it contains more N-sulfate and O-sulfate groups. Heparin proteoglycans are stored selectively in the secretory granules of mammalian mast cells. http://purl.obolibrary.org/obo/GO_0030210 heparin proteoglycan biosynthetic process http://purl.obolibrary.org/obo/GO_0180064 protein O-linked glycosylation via xylose The chemical reactions and pathways resulting in the formation of heparin proteoglycans, which consist of a core protein linked to a heparin glycosaminoglycan. The heparin chain is composed of the repeating disaccharide unit beta-(1,4)-N-acetyl-D-glucosamine-alpha-(1,4)-hexuronic acid, the former being either sulfated or deacetylated on its amino group as well as sulfated on one of its hydroxyl groups, and the latter being a mixture of sulfated and nonsulfated D-glucuronic and L-iduronic acids. Heparin is similar to heparan sulfate but it contains more N-sulfate and O-sulfate groups. Heparin chains are covalently linked to serine/threonine residues (O-linked) of the core protein via a tetrasaccharide linker sequence (xylose-galactose-galactose-glucuronate). http://purl.obolibrary.org/obo/GO_0030211 heparin proteoglycan catabolic process http://purl.obolibrary.org/obo/GO_0030202 heparin proteoglycan metabolic process The chemical reactions and pathways resulting in the breakdown of heparin proteoglycans, which consist of a core protein linked to a heparin glycosaminoglycan. The heparin chain is composed of the repeating disaccharide unit beta-(1,4)-N-acetyl-D-glucosamine-alpha-(1,4)-hexuronic acid, the former being either sulfated or deacetylated on its amino group as well as sulfated on one of its hydroxyl groups and the latter being a mixture of sulfated and nonsulfated D-glucuronic and L-iduronic acids. Heparin is similar to heparan sulfate but it contains more N-sulfate and O-sulfate groups. http://purl.obolibrary.org/obo/GO_0030212 hyaluronan metabolic process http://purl.obolibrary.org/obo/GO_0030203 glycosaminoglycan metabolic process The chemical reactions and pathways involving hyaluronan, the naturally occurring anionic form of hyaluronic acid. Hyaluronan is a type of non-sulfated glycosaminoglycan composed of the repeating disaccharide unit beta(1,4)-D-glucuronic acid-beta(1,3)-N-acetyl-D-glucosamine. http://purl.obolibrary.org/obo/GO_0030213 hyaluronan biosynthetic process http://purl.obolibrary.org/obo/GO_0030212 hyaluronan metabolic process The chemical reactions and pathways resulting in the formation of hyaluronan, the naturally occurring anionic form of hyaluronic acid. Hyaluronan is a type of non-sulfated glycosaminoglycan composed of the repeating disaccharide unit beta(1,4)-D-glucuronic acid-beta(1,3)-N-acetyl-D-glucosamine. http://purl.obolibrary.org/obo/GO_0030214 hyaluronan catabolic process http://purl.obolibrary.org/obo/GO_0030212 hyaluronan metabolic process The chemical reactions and pathways resulting in the breakdown of hyaluronan, the naturally occurring anionic form of hyaluronic acid. Hyaluronan is a type of non-sulfated glycosaminoglycan composed of the repeating disaccharide unit beta(1,4)-D-glucuronic acid-beta(1,3)-N-acetyl-D-glucosamine. http://purl.obolibrary.org/obo/GO_0030218 erythrocyte differentiation http://purl.obolibrary.org/obo/GO_0030099 myeloid cell differentiation The process in which a myeloid precursor cell acquires specializes features of an erythrocyte. http://purl.obolibrary.org/obo/GO_0030219 megakaryocyte differentiation http://purl.obolibrary.org/obo/GO_0030099 myeloid cell differentiation The process in which a myeloid precursor cell acquires specializes features of a megakaryocyte. http://purl.obolibrary.org/obo/GO_0030220 platelet formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process in which platelets bud from long processes extended by megakaryocytes. http://purl.obolibrary.org/obo/GO_0030221 basophil differentiation http://purl.obolibrary.org/obo/GO_0030851 granulocyte differentiation The process in which a relatively unspecialized myeloid precursor cell acquires specialized features of a basophil cell. http://purl.obolibrary.org/obo/GO_0030222 eosinophil differentiation http://purl.obolibrary.org/obo/GO_0030851 granulocyte differentiation The process in which a relatively unspecialized myeloid precursor cell acquires the specializes features of an eosinophil. http://purl.obolibrary.org/obo/GO_0030223 neutrophil differentiation http://purl.obolibrary.org/obo/GO_0030851 granulocyte differentiation The process in which a myeloid precursor cell acquires the specialized features of a neutrophil. http://purl.obolibrary.org/obo/GO_0030224 monocyte differentiation http://purl.obolibrary.org/obo/GO_1903131 mononuclear cell differentiation The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a monocyte. http://purl.obolibrary.org/obo/GO_0030252 growth hormone secretion http://purl.obolibrary.org/obo/GO_0030072 peptide hormone secretion The regulated release of growth hormone from secretory granules into the blood. http://purl.obolibrary.org/obo/GO_0030263 apoptotic chromosome condensation http://purl.obolibrary.org/obo/GO_0030261 chromosome condensation The compaction of chromatin during apoptosis. http://purl.obolibrary.org/obo/GO_0030264 nuclear fragmentation involved in apoptotic nuclear change http://purl.obolibrary.org/obo/GO_0071763 nuclear membrane organization The breakdown of the nucleus into small membrane-bounded compartments, or blebs, each of which contain compacted DNA. http://purl.obolibrary.org/obo/GO_0030278 regulation of ossification http://purl.obolibrary.org/obo/GO_0051239 regulation of multicellular organismal process Any process that modulates the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance. http://purl.obolibrary.org/obo/GO_0030279 negative regulation of ossification http://purl.obolibrary.org/obo/GO_0030278 regulation of ossification Any process that stops, prevents, or reduces the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance. http://purl.obolibrary.org/obo/GO_0030282 bone mineralization http://purl.obolibrary.org/obo/GO_0031214 biomineral tissue development The deposition of hydroxyapatite, a form of calcium phosphate with the formula Ca10(PO4)6(OH)2, in bone tissue. http://purl.obolibrary.org/obo/GO_0030307 positive regulation of cell growth http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the frequency, rate, extent or direction of cell growth. http://purl.obolibrary.org/obo/GO_0030308 negative regulation of cell growth http://purl.obolibrary.org/obo/GO_0045926 negative regulation of growth Any process that stops, prevents, or reduces the frequency, rate, extent or direction of cell growth. http://purl.obolibrary.org/obo/GO_0030316 osteoclast differentiation http://purl.obolibrary.org/obo/GO_0002573 myeloid leukocyte differentiation The process in which a relatively unspecialized monocyte acquires the specialized features of an osteoclast. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue. http://purl.obolibrary.org/obo/GO_0030318 melanocyte differentiation http://purl.obolibrary.org/obo/GO_0050931 pigment cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a melanocyte. http://purl.obolibrary.org/obo/GO_0030323 respiratory tube development http://purl.obolibrary.org/obo/GO_0048513 animal organ development The process whose specific outcome is the progression of the respiratory tube over time, from its formation to the mature structure. The respiratory tube is assumed to mean any tube in the respiratory tract. http://purl.obolibrary.org/obo/GO_0030324 lung development http://purl.obolibrary.org/obo/GO_0048513 animal organ development The process whose specific outcome is the progression of the lung over time, from its formation to the mature structure. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the esophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into tubes ending in small air cells, in the walls of which the blood circulates in a fine network of capillaries. In mammals the lungs are more or less divided into lobes, and each lung occupies a separate cavity in the thorax. http://purl.obolibrary.org/obo/GO_0030325 adrenal gland development http://purl.obolibrary.org/obo/GO_0048732 gland development The process whose specific outcome is the progression of the adrenal gland over time, from its formation to the mature structure. This gland can either be a discrete structure located bilaterally above each kidney, or a cluster of cells in the head kidney that perform the functions of the adrenal gland. In either case, this organ consists of two cells types, aminergic chromaffin cells and steroidogenic cortical cells. http://purl.obolibrary.org/obo/GO_0030331 nuclear estrogen receptor binding http://purl.obolibrary.org/obo/GO_0016922 nuclear receptor binding Binding to a nuclear estrogen receptor. http://purl.obolibrary.org/obo/GO_0030382 sperm mitochondrion organization http://purl.obolibrary.org/obo/GO_0007005 mitochondrion organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of sperm mitochondria; the process in which they take on their characteristic morphology; they are flattened, elongated, and arranged circumferentially into a tight helical coil around the tail-dense fibers of the mature sperm. http://purl.obolibrary.org/obo/GO_0030421 defecation http://purl.obolibrary.org/obo/GO_0022600 digestive system process The expulsion of feces from the rectum. http://purl.obolibrary.org/obo/GO_0030424 axon http://purl.obolibrary.org/obo/GO_0043005 neuron projection The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter. http://purl.obolibrary.org/obo/GO_0030425 dendrite http://purl.obolibrary.org/obo/GO_0043005 neuron projection A neuron projection that has a short, tapering, morphology. Dendrites receive and integrate signals from other neurons or from sensory stimuli, and conduct nerve impulses towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body. http://purl.obolibrary.org/obo/GO_0030432 peristalsis http://purl.obolibrary.org/obo/GO_0014821 phasic smooth muscle contraction A wavelike sequence of involuntary muscular contraction and relaxation that passes along a tubelike structure, such as the intestine, impelling the contents onwards. http://purl.obolibrary.org/obo/GO_0030435 sporulation resulting in formation of a cellular spore http://purl.obolibrary.org/obo/GO_0043934 sporulation The process in which a relatively unspecialized cell acquires the specialized features of a cellular spore, a cell form that can be used for dissemination, for survival of adverse conditions because of its heat and desiccation resistance, and/or for reproduction. http://purl.obolibrary.org/obo/GO_0030485 smooth muscle contractile fiber http://purl.obolibrary.org/obo/GO_0043292 contractile muscle fiber The contractile fiber of smooth muscle cells. http://purl.obolibrary.org/obo/GO_0030500 regulation of bone mineralization http://purl.obolibrary.org/obo/GO_0070167 regulation of biomineral tissue development Any process that modulates the frequency, rate or extent of bone mineralization. http://purl.obolibrary.org/obo/GO_0030501 positive regulation of bone mineralization http://purl.obolibrary.org/obo/GO_0070169 positive regulation of biomineral tissue development Any process that activates or increases the frequency, rate or extent of bone mineralization. http://purl.obolibrary.org/obo/GO_0030502 negative regulation of bone mineralization http://purl.obolibrary.org/obo/GO_0070168 negative regulation of biomineral tissue development Any process that stops, prevents, or reduces the frequency, rate or extent of bone mineralization. http://purl.obolibrary.org/obo/GO_0030539 male genitalia development http://purl.obolibrary.org/obo/GO_0061458 reproductive system development The process whose specific outcome is the progression of the male genitalia over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0030573 bile acid catabolic process http://purl.obolibrary.org/obo/GO_0008206 bile acid metabolic process The chemical reactions and pathways resulting in the breakdown of bile acids, any of a group of steroid carboxylic acids occurring in bile. http://purl.obolibrary.org/obo/GO_0030593 neutrophil chemotaxis http://purl.obolibrary.org/obo/GO_1990266 neutrophil migration The directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding. http://purl.obolibrary.org/obo/GO_0030643 intracellular phosphate ion homeostasis http://purl.obolibrary.org/obo/GO_0055062 phosphate ion homeostasis A homeostatic process involved in the maintenance of a steady state level of phosphate ions within a cell. http://purl.obolibrary.org/obo/GO_0030659 cytoplasmic vesicle membrane http://purl.obolibrary.org/obo/GO_0012506 vesicle membrane The lipid bilayer surrounding a cytoplasmic vesicle. http://purl.obolibrary.org/obo/GO_0030661 chitosome membrane http://purl.obolibrary.org/obo/GO_0030659 cytoplasmic vesicle membrane The lipid bilayer surrounding a chitosome. http://purl.obolibrary.org/obo/GO_0030718 germ-line stem cell population maintenance http://purl.obolibrary.org/obo/GO_0019827 stem cell population maintenance Any process by which an organism or tissue maintains a population of germ-line stem cells. http://purl.obolibrary.org/obo/GO_0030720 oocyte localization involved in germarium-derived egg chamber formation http://purl.obolibrary.org/obo/GO_0051674 localization of cell Directed movement of the oocyte, following its specification, from its original central position in the cyst to a posterior position relative to the nurse cells of the egg chamber, and its maintenance in this posterior location. This is the first sign of anterior-posterior asymmetry in the developing egg chamber. http://purl.obolibrary.org/obo/GO_0030808 regulation of nucleotide biosynthetic process http://purl.obolibrary.org/obo/GO_0009889 regulation of biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nucleotides. http://purl.obolibrary.org/obo/GO_0030809 negative regulation of nucleotide biosynthetic process http://purl.obolibrary.org/obo/GO_0009890 negative regulation of biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nucleotides. http://purl.obolibrary.org/obo/GO_0030810 positive regulation of nucleotide biosynthetic process http://purl.obolibrary.org/obo/GO_0009891 positive regulation of biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nucleotides. http://purl.obolibrary.org/obo/GO_0030811 regulation of nucleotide catabolic process http://purl.obolibrary.org/obo/GO_0009894 regulation of catabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of nucleotides. http://purl.obolibrary.org/obo/GO_0030812 negative regulation of nucleotide catabolic process http://purl.obolibrary.org/obo/GO_0009895 negative regulation of catabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of nucleotides. http://purl.obolibrary.org/obo/GO_0030813 positive regulation of nucleotide catabolic process http://purl.obolibrary.org/obo/GO_0009896 positive regulation of catabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of nucleotides. http://purl.obolibrary.org/obo/GO_0030849 autosome http://purl.obolibrary.org/obo/GO_0005694 chromosome Any chromosome other than a sex chromosome. http://purl.obolibrary.org/obo/GO_0030850 prostate gland development http://purl.obolibrary.org/obo/GO_0048732 gland development The process whose specific outcome is the progression of the prostate gland over time, from its formation to the mature structure. The prostate gland is a partly muscular, partly glandular body that is situated near the base of the mammalian male urethra and secretes an alkaline viscid fluid which is a major constituent of the ejaculatory fluid. http://purl.obolibrary.org/obo/GO_0030851 granulocyte differentiation http://purl.obolibrary.org/obo/GO_0002573 myeloid leukocyte differentiation The process in which a myeloid precursor cell acquires the specialized features of a granulocyte. Granulocytes are a class of leukocytes characterized by the presence of granules in their cytoplasm. These cells are active in allergic immune reactions such as arthritic inflammation and rashes. This class includes basophils, eosinophils and neutrophils. http://purl.obolibrary.org/obo/GO_0030852 regulation of granulocyte differentiation http://purl.obolibrary.org/obo/GO_0002761 regulation of myeloid leukocyte differentiation Any process that modulates the frequency, rate or extent of granulocyte differentiation. http://purl.obolibrary.org/obo/GO_0030853 negative regulation of granulocyte differentiation http://purl.obolibrary.org/obo/GO_0030852 regulation of granulocyte differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of granulocyte differentiation. http://purl.obolibrary.org/obo/GO_0030854 positive regulation of granulocyte differentiation http://purl.obolibrary.org/obo/GO_0030852 regulation of granulocyte differentiation Any process that activates or increases the frequency, rate or extent of granulocyte differentiation. http://purl.obolibrary.org/obo/GO_0030856 regulation of epithelial cell differentiation http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the frequency, rate or extent of epithelial cell differentiation. http://purl.obolibrary.org/obo/GO_0030858 positive regulation of epithelial cell differentiation http://purl.obolibrary.org/obo/GO_0045597 positive regulation of cell differentiation Any process that activates or increases the frequency, rate or extent of epithelial cell differentiation. http://purl.obolibrary.org/obo/GO_0030878 thyroid gland development http://purl.obolibrary.org/obo/GO_0048732 gland development The process whose specific outcome is the progression of the thyroid gland over time, from its formation to the mature structure. The thyroid gland is an endoderm-derived gland that produces thyroid hormone. http://purl.obolibrary.org/obo/GO_0030885 regulation of myeloid dendritic cell activation http://purl.obolibrary.org/obo/GO_0002694 regulation of leukocyte activation Any process that modulates the frequency or rate of myeloid dendritic cell activation. http://purl.obolibrary.org/obo/GO_0030886 negative regulation of myeloid dendritic cell activation http://purl.obolibrary.org/obo/GO_0030885 regulation of myeloid dendritic cell activation Any process that stops, prevents, or reduces the frequency, rate or extent of myeloid dendritic cell activation. http://purl.obolibrary.org/obo/GO_0030887 positive regulation of myeloid dendritic cell activation http://purl.obolibrary.org/obo/GO_0030885 regulation of myeloid dendritic cell activation Any process that stimulates, induces or increases the rate of myeloid dendritic cell activation. http://purl.obolibrary.org/obo/GO_0030888 regulation of B cell proliferation http://purl.obolibrary.org/obo/GO_0050864 regulation of B cell activation Any process that modulates the frequency, rate or extent of B cell proliferation. http://purl.obolibrary.org/obo/GO_0030889 negative regulation of B cell proliferation http://purl.obolibrary.org/obo/GO_0050869 negative regulation of B cell activation Any process that stops, prevents or reduces the rate or extent of B cell proliferation. http://purl.obolibrary.org/obo/GO_0030890 positive regulation of B cell proliferation http://purl.obolibrary.org/obo/GO_0050871 positive regulation of B cell activation Any process that activates or increases the rate or extent of B cell proliferation. http://purl.obolibrary.org/obo/GO_0030900 forebrain development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the forebrain over time, from its formation to the mature structure. The forebrain is the anterior of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes especially the cerebral hemispheres, the thalamus, and the hypothalamus and especially in higher vertebrates is the main control center for sensory and associative information processing, visceral functions, and voluntary motor functions). http://purl.obolibrary.org/obo/GO_0030901 midbrain development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the midbrain over time, from its formation to the mature structure. The midbrain is the middle division of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes a ventral part containing the cerebral peduncles and a dorsal tectum containing the corpora quadrigemina and that surrounds the aqueduct of Sylvius connecting the third and fourth ventricles). http://purl.obolibrary.org/obo/GO_0030902 hindbrain development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the hindbrain over time, from its formation to the mature structure. The hindbrain is the posterior of the three primary divisions of the developing chordate brain, or the corresponding part of the adult brain (in vertebrates, includes the cerebellum, pons, and medulla oblongata and controls the autonomic functions and equilibrium). http://purl.obolibrary.org/obo/GO_0030903 notochord development http://purl.obolibrary.org/obo/GO_0048568 embryonic organ development The process whose specific outcome is the progression of the notochord over time, from its formation to the mature structure. The notochord is a mesoderm-derived structure located ventral of the developing nerve cord. In vertebrates, the notochord serves as a core around which other mesodermal cells form the vertebrae. In the most primitive chordates, which lack vertebrae, the notochord persists as a substitute for a vertebral column. http://purl.obolibrary.org/obo/GO_0030910 olfactory placode formation http://purl.obolibrary.org/obo/GO_0060788 ectodermal placode formation The formation of a thickening of the neural ectoderm in the head region of the vertebrate embryo which develops into the olfactory region of the nasal cavity. http://purl.obolibrary.org/obo/GO_0030916 otic vesicle formation http://purl.obolibrary.org/obo/GO_0072175 epithelial tube formation The process resulting in the transition of the otic placode into the otic vesicle, a transient embryonic structure formed during development of the vertebrate inner ear. http://purl.obolibrary.org/obo/GO_0030917 midbrain-hindbrain boundary development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the midbrain-hindbrain boundary over time, from its formation to the mature structure. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. http://purl.obolibrary.org/obo/GO_0030955 potassium ion binding http://purl.obolibrary.org/obo/GO_0031420 alkali metal ion binding Binding to a potassium ion (K+). http://purl.obolibrary.org/obo/GO_0031016 pancreas development http://purl.obolibrary.org/obo/GO_0048513 animal organ development The process whose specific outcome is the progression of the pancreas over time, from its formation to the mature structure. The pancreas is an endoderm derived structure that produces precursors of digestive enzymes and blood glucose regulating hormones. http://purl.obolibrary.org/obo/GO_0031017 exocrine pancreas development http://purl.obolibrary.org/obo/GO_0048732 gland development The process whose specific outcome is the progression of the exocrine pancreas over time, from its formation to the mature structure. The exocrine pancreas produces and store zymogens of digestive enzymes, such as chymotrypsinogen and trypsinogen in the acinar cells. http://purl.obolibrary.org/obo/GO_0031022 nuclear migration along microfilament http://purl.obolibrary.org/obo/GO_0099515 actin filament-based transport The directed movement of the nucleus along microfilaments within the cell, mediated by motor proteins. http://purl.obolibrary.org/obo/GO_0031023 microtubule organizing center organization http://purl.obolibrary.org/obo/GO_0007017 microtubule-based process A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microtubule organizing center, a structure from which microtubules grow. http://purl.obolibrary.org/obo/GO_0031045 dense core granule http://purl.obolibrary.org/obo/GO_0030141 secretory granule Electron-dense organelle with a granular internal matrix; contains proteins destined to be secreted. http://purl.obolibrary.org/obo/GO_0031069 hair follicle morphogenesis http://purl.obolibrary.org/obo/GO_0022405 hair cycle process The process in which the anatomical structures of the hair follicle are generated and organized. http://purl.obolibrary.org/obo/GO_0031076 embryonic camera-type eye development http://purl.obolibrary.org/obo/GO_0048568 embryonic organ development The process occurring during the embryonic phase whose specific outcome is the progression of the eye over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0031099 regeneration http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The regrowth of a lost or destroyed body part, such as an organ or tissue. This process may occur via renewal, repair, and/or growth alone (i.e. increase in size or mass). http://purl.obolibrary.org/obo/GO_0031100 animal organ regeneration http://purl.obolibrary.org/obo/GO_0031099 regeneration The regrowth of a lost or destroyed animal organ. http://purl.obolibrary.org/obo/GO_0031110 regulation of microtubule polymerization or depolymerization http://purl.obolibrary.org/obo/GO_0070507 regulation of microtubule cytoskeleton organization Any process that modulates the frequency, rate or extent of microtubule polymerization or depolymerization by the addition or removal of tubulin heterodimers from a microtubule. http://purl.obolibrary.org/obo/GO_0031112 positive regulation of microtubule polymerization or depolymerization http://purl.obolibrary.org/obo/GO_0051495 positive regulation of cytoskeleton organization Any process that activates or increases the frequency, rate or extent of microtubule polymerization or depolymerization. http://purl.obolibrary.org/obo/GO_0031115 negative regulation of microtubule polymerization http://purl.obolibrary.org/obo/GO_0031113 regulation of microtubule polymerization Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule polymerization. http://purl.obolibrary.org/obo/GO_0031116 positive regulation of microtubule polymerization http://purl.obolibrary.org/obo/GO_0031113 regulation of microtubule polymerization Any process that activates or increases the frequency, rate or extent of microtubule polymerization. http://purl.obolibrary.org/obo/GO_0031117 positive regulation of microtubule depolymerization http://purl.obolibrary.org/obo/GO_1902905 positive regulation of supramolecular fiber organization Any process that activates or increases the frequency, rate or extent of microtubule depolymerization. http://purl.obolibrary.org/obo/GO_0031143 pseudopodium http://purl.obolibrary.org/obo/GO_0120025 plasma membrane bounded cell projection A temporary protrusion or retractile process of a cell, associated with flowing movements of the protoplasm, and serving for locomotion and feeding. http://purl.obolibrary.org/obo/GO_0031201 SNARE complex http://purl.obolibrary.org/obo/GO_0098796 membrane protein complex A protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers. One well-characterized example is the neuronal SNARE complex formed of synaptobrevin 2, syntaxin 1a, and SNAP-25. http://purl.obolibrary.org/obo/GO_0031214 biomineral tissue development http://purl.obolibrary.org/obo/GO_0009888 tissue development Formation of hard tissues that consist mainly of inorganic compounds, and also contain a small amounts of organic matrices that are believed to play important roles in their formation. http://purl.obolibrary.org/obo/GO_0031253 cell projection membrane http://purl.obolibrary.org/obo/GO_0098590 plasma membrane region The portion of the plasma membrane surrounding a plasma membrane bounded cell surface projection. http://purl.obolibrary.org/obo/GO_0031256 leading edge membrane http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure The portion of the plasma membrane surrounding the leading edge of a motile cell. http://purl.obolibrary.org/obo/GO_0031268 pseudopodium organization http://purl.obolibrary.org/obo/GO_0120036 plasma membrane bounded cell projection organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a pseudopodium, a temporary protrusion or retractile process of a cell, associated with cellular movement. http://purl.obolibrary.org/obo/GO_0031269 pseudopodium assembly http://purl.obolibrary.org/obo/GO_0120031 plasma membrane bounded cell projection assembly The assembly of a pseudopodium by rearrangement of the actin cytoskeleton and overlying membrane. http://purl.obolibrary.org/obo/GO_0031270 pseudopodium retraction http://purl.obolibrary.org/obo/GO_0031268 pseudopodium organization The myosin-based contraction and retraction of a pseudopodium. http://purl.obolibrary.org/obo/GO_0031272 regulation of pseudopodium assembly http://purl.obolibrary.org/obo/GO_0120032 regulation of plasma membrane bounded cell projection assembly Any process that modulates the frequency, rate or extent of the assembly of pseudopodia. http://purl.obolibrary.org/obo/GO_0031273 negative regulation of pseudopodium assembly http://purl.obolibrary.org/obo/GO_0120033 negative regulation of plasma membrane bounded cell projection assembly Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of pseudopodia. http://purl.obolibrary.org/obo/GO_0031274 positive regulation of pseudopodium assembly http://purl.obolibrary.org/obo/GO_0120034 positive regulation of plasma membrane bounded cell projection assembly Any process that activates or increases the frequency, rate or extent of the assembly of pseudopodia. http://purl.obolibrary.org/obo/GO_0031294 lymphocyte costimulation http://purl.obolibrary.org/obo/GO_0051251 positive regulation of lymphocyte activation The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the B- or T cell receptor to augment B- or T cell activation. http://purl.obolibrary.org/obo/GO_0031295 T cell costimulation http://purl.obolibrary.org/obo/GO_0050870 positive regulation of T cell activation The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the T cell receptor to augment T cell activation. http://purl.obolibrary.org/obo/GO_0031296 B cell costimulation http://purl.obolibrary.org/obo/GO_0050871 positive regulation of B cell activation The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the B cell receptor to augment B cell activation. http://purl.obolibrary.org/obo/GO_0031338 regulation of vesicle fusion http://purl.obolibrary.org/obo/GO_0060627 regulation of vesicle-mediated transport Any process that modulates the frequency, rate or extent of vesicle fusion. http://purl.obolibrary.org/obo/GO_0031339 negative regulation of vesicle fusion http://purl.obolibrary.org/obo/GO_0051051 negative regulation of transport Any process that stops, prevents, or reduces the frequency, rate or extent of vesicle fusion. http://purl.obolibrary.org/obo/GO_0031340 positive regulation of vesicle fusion http://purl.obolibrary.org/obo/GO_0051050 positive regulation of transport Any process that activates or increases the frequency, rate or extent of vesicle fusion. http://purl.obolibrary.org/obo/GO_0031402 sodium ion binding http://purl.obolibrary.org/obo/GO_0031420 alkali metal ion binding Binding to a sodium ion (Na+). http://purl.obolibrary.org/obo/GO_0031409 pigment binding http://purl.obolibrary.org/obo/GO_0005488 binding Binding to a pigment, a general or particular coloring matter in living organisms, e.g. melanin. http://purl.obolibrary.org/obo/GO_0031420 alkali metal ion binding http://purl.obolibrary.org/obo/GO_0046872 metal ion binding Binding to an alkali metal ion; alkali metals are those elements in group Ia of the periodic table, with the exception of hydrogen. http://purl.obolibrary.org/obo/GO_0031424 keratinization http://purl.obolibrary.org/obo/GO_0032501 multicellular organismal process The process in which the cytoplasm of the outermost cells of the vertebrate epidermis is replaced by keratin. Keratinization occurs in the stratum corneum, feathers, hair, claws, nails, hooves, and horns. http://purl.obolibrary.org/obo/GO_0031445 regulation of heterochromatin formation http://purl.obolibrary.org/obo/GO_0010468 regulation of gene expression Any process that modulates the frequency, rate, extent or location of heterochromatin formation. http://purl.obolibrary.org/obo/GO_0031452 negative regulation of heterochromatin formation http://purl.obolibrary.org/obo/GO_0010628 positive regulation of gene expression Any process that stops, prevents, or reduces the frequency, rate or extent of heterochromatin formation. http://purl.obolibrary.org/obo/GO_0031453 positive regulation of heterochromatin formation http://purl.obolibrary.org/obo/GO_0044089 positive regulation of cellular component biogenesis Any process that activates or increases the frequency, rate or extent of heterochromatin formation. http://purl.obolibrary.org/obo/GO_0031503 protein-containing complex localization http://purl.obolibrary.org/obo/GO_0033036 macromolecule localization A localization process that acts on a protein complex; the complex is transported to, or maintained in, a specific location. http://purl.obolibrary.org/obo/GO_0031507 heterochromatin formation http://purl.obolibrary.org/obo/GO_0070828 heterochromatin organization An epigenetic gene silencing mechanism in which chromatin is compacted into heterochromatin, resulting in a chromatin conformation refractory to transcription. This process starts with heterochromatin nucleation, its spreading, and ends with heterochromatin boundary formation. http://purl.obolibrary.org/obo/GO_0031594 neuromuscular junction http://purl.obolibrary.org/obo/GO_0045202 synapse The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a change in post-synaptic potential. http://purl.obolibrary.org/obo/GO_0031641 regulation of myelination http://purl.obolibrary.org/obo/GO_0051960 regulation of nervous system development Any process that modulates the frequency, rate or extent of the formation of a myelin sheath around nerve axons. http://purl.obolibrary.org/obo/GO_0031642 negative regulation of myelination http://purl.obolibrary.org/obo/GO_0031645 negative regulation of nervous system process Any process that stops, prevents, or reduces the frequency, rate or extent of the formation of a myelin sheath around nerve axons. http://purl.obolibrary.org/obo/GO_0031643 positive regulation of myelination http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the frequency, rate or extent of the formation of a myelin sheath around nerve axons. http://purl.obolibrary.org/obo/GO_0031644 regulation of nervous system process http://purl.obolibrary.org/obo/GO_0044057 regulation of system process Any process that modulates the frequency, rate or extent of a neurophysiological process, an organ system process carried out by any of the organs or tissues of the nervous system. http://purl.obolibrary.org/obo/GO_0031645 negative regulation of nervous system process http://purl.obolibrary.org/obo/GO_0031644 regulation of nervous system process Any process that stops, prevents, or reduces the frequency, rate or extent of a neurophysiological process. http://purl.obolibrary.org/obo/GO_0031646 positive regulation of nervous system process http://purl.obolibrary.org/obo/GO_0031644 regulation of nervous system process Any process that activates or increases the frequency, rate or extent of a neurophysiological process. http://purl.obolibrary.org/obo/GO_0031723 CXCR4 chemokine receptor binding http://purl.obolibrary.org/obo/GO_0045236 CXCR chemokine receptor binding Binding to a CXCR4 chemokine receptor. http://purl.obolibrary.org/obo/GO_0031727 CCR2 chemokine receptor binding http://purl.obolibrary.org/obo/GO_0048020 CCR chemokine receptor binding Binding to a CCR2 chemokine receptor. http://purl.obolibrary.org/obo/GO_0031728 CCR3 chemokine receptor binding http://purl.obolibrary.org/obo/GO_0048020 CCR chemokine receptor binding Binding to a CCR3 chemokine receptor. http://purl.obolibrary.org/obo/GO_0031731 CCR6 chemokine receptor binding http://purl.obolibrary.org/obo/GO_0048020 CCR chemokine receptor binding Binding to a CCR6 chemokine receptor. http://purl.obolibrary.org/obo/GO_0031732 CCR7 chemokine receptor binding http://purl.obolibrary.org/obo/GO_0048020 CCR chemokine receptor binding Binding to a CCR7 chemokine receptor. http://purl.obolibrary.org/obo/GO_0031737 CX3C chemokine receptor binding http://purl.obolibrary.org/obo/GO_0042379 chemokine receptor binding Binding to a CX3C chemokine receptor. http://purl.obolibrary.org/obo/GO_0031761 fMet-Leu-Phe receptor binding http://purl.obolibrary.org/obo/GO_0001664 G protein-coupled receptor binding Binding to a fMet-Leu-Phe receptor. http://purl.obolibrary.org/obo/GO_0031855 oxytocin receptor binding http://purl.obolibrary.org/obo/GO_0001664 G protein-coupled receptor binding Binding to an oxytocin receptor. http://purl.obolibrary.org/obo/GO_0031862 prostanoid receptor binding http://purl.obolibrary.org/obo/GO_0001664 G protein-coupled receptor binding Binding to a prostanoid receptor. http://purl.obolibrary.org/obo/GO_0031943 regulation of glucocorticoid metabolic process http://purl.obolibrary.org/obo/GO_0032350 regulation of hormone metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving glucocorticoids. http://purl.obolibrary.org/obo/GO_0031946 regulation of glucocorticoid biosynthetic process http://purl.obolibrary.org/obo/GO_0031943 regulation of glucocorticoid metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucocorticoids. http://purl.obolibrary.org/obo/GO_0031947 negative regulation of glucocorticoid biosynthetic process http://purl.obolibrary.org/obo/GO_0090032 negative regulation of steroid hormone biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucocorticoids. http://purl.obolibrary.org/obo/GO_0031948 positive regulation of glucocorticoid biosynthetic process http://purl.obolibrary.org/obo/GO_0090031 positive regulation of steroid hormone biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucocorticoids. http://purl.obolibrary.org/obo/GO_0031949 regulation of glucocorticoid catabolic process http://purl.obolibrary.org/obo/GO_0050994 regulation of lipid catabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glucocorticoids. http://purl.obolibrary.org/obo/GO_0031950 negative regulation of glucocorticoid catabolic process http://purl.obolibrary.org/obo/GO_0050995 negative regulation of lipid catabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glucocorticoids. http://purl.obolibrary.org/obo/GO_0031951 positive regulation of glucocorticoid catabolic process http://purl.obolibrary.org/obo/GO_0050996 positive regulation of lipid catabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glucocorticoids. http://purl.obolibrary.org/obo/GO_0031960 response to corticosteroid http://purl.obolibrary.org/obo/GO_0048545 response to steroid hormone Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosteroid hormone stimulus. A corticosteroid is a steroid hormone that is produced in the adrenal cortex. Corticosteroids are involved in a wide range of physiologic systems such as stress response, immune response and regulation of inflammation, carbohydrate metabolism, protein catabolism, blood electrolyte levels, and behavior. They include glucocorticoids and mineralocorticoids. http://purl.obolibrary.org/obo/GO_0031987 locomotion involved in locomotory behavior http://purl.obolibrary.org/obo/GO_0040011 locomotion Self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement. http://purl.obolibrary.org/obo/GO_0032024 positive regulation of insulin secretion http://purl.obolibrary.org/obo/GO_0090277 positive regulation of peptide hormone secretion Any process that activates or increases the frequency, rate or extent of the regulated release of insulin. http://purl.obolibrary.org/obo/GO_0032043 mitochondrial DNA catabolic process http://purl.obolibrary.org/obo/GO_0006308 DNA catabolic process The chemical reactions and pathways resulting in the breakdown of mitochondrial DNA. http://purl.obolibrary.org/obo/GO_0032052 bile acid binding http://purl.obolibrary.org/obo/GO_0033293 monocarboxylic acid binding Binding to a bile acid, a steroid carboxylic acids occurring in bile. http://purl.obolibrary.org/obo/GO_0032053 ciliary basal body organization http://purl.obolibrary.org/obo/GO_0044782 cilium organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a ciliary basal body, a short cylindrical array of microtubules and associated proteins found at the base of a eukaryotic cilium (also called flagellum). http://purl.obolibrary.org/obo/GO_0032055 negative regulation of translation in response to stress http://purl.obolibrary.org/obo/GO_0043555 regulation of translation in response to stress Any process that stops, prevents or reduces the rate of translation as a result of a stimulus indicating the organism is under stress. http://purl.obolibrary.org/obo/GO_0032057 negative regulation of translational initiation in response to stress http://purl.obolibrary.org/obo/GO_0045947 negative regulation of translational initiation Any process that stops, prevents or reduces the rate of translation initiation as a result of a stimulus indicating the organism is under stress. http://purl.obolibrary.org/obo/GO_0032058 positive regulation of translational initiation in response to stress http://purl.obolibrary.org/obo/GO_0045948 positive regulation of translational initiation Any process that activates or increases the frequency, rate or extent of translation initiation as a result of a stimulus indicating the organism is under stress. http://purl.obolibrary.org/obo/GO_0032059 bleb http://purl.obolibrary.org/obo/GO_0120025 plasma membrane bounded cell projection A cell extension caused by localized decoupling of the cytoskeleton from the plasma membrane and characterized by rapid formation, rounded shape, and scarcity of organelles within the protrusion. Blebs are formed during apoptosis and other cellular processes, including cell locomotion, cell division, and as a result of physical or chemical stresses. http://purl.obolibrary.org/obo/GO_0032060 bleb assembly http://purl.obolibrary.org/obo/GO_0120031 plasma membrane bounded cell projection assembly The assembly of a bleb, a cell extension caused by localized decoupling of the cytoskeleton from the plasma membrane and characterized by rapid formation, rounded shape, and scarcity of organelles within the protrusion. Plasma membrane blebbing occurs during apoptosis and other cellular processes, including cell locomotion, cell division, and as a result of physical or chemical stresses. http://purl.obolibrary.org/obo/GO_0032065 maintenance of protein location in cell cortex http://purl.obolibrary.org/obo/GO_0032507 maintenance of protein location in cell A process in which a protein or protein complex is maintained in a specific location in the cell cortex. http://purl.obolibrary.org/obo/GO_0032077 positive regulation of deoxyribonuclease activity http://purl.obolibrary.org/obo/GO_0051054 positive regulation of DNA metabolic process Any process that activates or increases the frequency, rate or extent of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid. http://purl.obolibrary.org/obo/GO_0032092 positive regulation of protein binding http://purl.obolibrary.org/obo/GO_0051099 positive regulation of binding Any process that activates or increases the frequency, rate or extent of protein binding. http://purl.obolibrary.org/obo/GO_0032127 dense core granule membrane http://purl.obolibrary.org/obo/GO_0030667 secretory granule membrane The lipid bilayer surrounding a dense core granule. http://purl.obolibrary.org/obo/GO_0032225 regulation of synaptic transmission, dopaminergic http://purl.obolibrary.org/obo/GO_0050804 modulation of chemical synaptic transmission Any process that modulates the frequency, rate or extent of dopaminergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter dopamine. http://purl.obolibrary.org/obo/GO_0032226 positive regulation of synaptic transmission, dopaminergic http://purl.obolibrary.org/obo/GO_0032225 regulation of synaptic transmission, dopaminergic Any process that activates, maintains or increases the frequency, rate or extent of dopaminergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter dopamine. http://purl.obolibrary.org/obo/GO_0032227 negative regulation of synaptic transmission, dopaminergic http://purl.obolibrary.org/obo/GO_0050805 negative regulation of synaptic transmission Any process that stops, prevents, or reduces the frequency, rate or extent of dopaminergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter dopamine. http://purl.obolibrary.org/obo/GO_0032228 regulation of synaptic transmission, GABAergic http://purl.obolibrary.org/obo/GO_0050804 modulation of chemical synaptic transmission Any process that modulates the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA). http://purl.obolibrary.org/obo/GO_0032229 negative regulation of synaptic transmission, GABAergic http://purl.obolibrary.org/obo/GO_0050805 negative regulation of synaptic transmission Any process that stops, prevents, or reduces the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA). http://purl.obolibrary.org/obo/GO_0032230 positive regulation of synaptic transmission, GABAergic http://purl.obolibrary.org/obo/GO_0032228 regulation of synaptic transmission, GABAergic Any process that activates, maintains or increases the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA). http://purl.obolibrary.org/obo/GO_0032231 regulation of actin filament bundle assembly http://purl.obolibrary.org/obo/GO_0110053 regulation of actin filament organization Any process that modulates the frequency, rate or extent of the assembly of actin filament bundles. http://purl.obolibrary.org/obo/GO_0032232 negative regulation of actin filament bundle assembly http://purl.obolibrary.org/obo/GO_0051494 negative regulation of cytoskeleton organization Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of actin filament bundles. http://purl.obolibrary.org/obo/GO_0032233 positive regulation of actin filament bundle assembly http://purl.obolibrary.org/obo/GO_0051495 positive regulation of cytoskeleton organization Any process that activates or increases the frequency, rate or extent of the assembly of actin filament bundles. http://purl.obolibrary.org/obo/GO_0032239 regulation of nucleobase-containing compound transport http://purl.obolibrary.org/obo/GO_0051049 regulation of transport Any process that modulates the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0032240 negative regulation of nucleobase-containing compound transport http://purl.obolibrary.org/obo/GO_0051051 negative regulation of transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0032241 positive regulation of nucleobase-containing compound transport http://purl.obolibrary.org/obo/GO_0051050 positive regulation of transport Any process that activates or increases the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0032252 secretory granule localization http://purl.obolibrary.org/obo/GO_0051648 vesicle localization Any process in which a secretory granule is transported to, and/or maintained in, a specific location within the cell. http://purl.obolibrary.org/obo/GO_0032253 dense core granule localization http://purl.obolibrary.org/obo/GO_0032252 secretory granule localization Any process in which a dense core granule is transported to, and/or maintained in, a specific location within the cell. http://purl.obolibrary.org/obo/GO_0032272 negative regulation of protein polymerization http://purl.obolibrary.org/obo/GO_0032271 regulation of protein polymerization Any process that stops, prevents, or reduces the frequency, rate or extent of the process of creating protein polymers. http://purl.obolibrary.org/obo/GO_0032273 positive regulation of protein polymerization http://purl.obolibrary.org/obo/GO_0032271 regulation of protein polymerization Any process that activates or increases the frequency, rate or extent of the process of creating protein polymers. http://purl.obolibrary.org/obo/GO_0032274 gonadotropin secretion http://purl.obolibrary.org/obo/GO_0060986 endocrine hormone secretion The regulated release of a gonadotropin, any hormone that stimulates the gonads, especially follicle-stimulating hormone and luteinizing hormone. http://purl.obolibrary.org/obo/GO_0032275 luteinizing hormone secretion http://purl.obolibrary.org/obo/GO_0032274 gonadotropin secretion The regulated release of luteinizing hormone, a gonadotropic glycoprotein hormone secreted by the anterior pituitary. http://purl.obolibrary.org/obo/GO_0032276 regulation of gonadotropin secretion http://purl.obolibrary.org/obo/GO_0046883 regulation of hormone secretion Any process that modulates the frequency, rate or extent of the regulated release of a gonadotropin. http://purl.obolibrary.org/obo/GO_0032277 negative regulation of gonadotropin secretion http://purl.obolibrary.org/obo/GO_0046888 negative regulation of hormone secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a gonadotropin. http://purl.obolibrary.org/obo/GO_0032278 positive regulation of gonadotropin secretion http://purl.obolibrary.org/obo/GO_0046887 positive regulation of hormone secretion Any process that activates or increases the frequency, rate or extent of the regulated release of a gonadotropin. http://purl.obolibrary.org/obo/GO_0032288 myelin assembly http://purl.obolibrary.org/obo/GO_0010927 cellular component assembly involved in morphogenesis The process in which the wraps of cell membrane that constitute myelin are laid down around an axon in the central or peripheral nervous system. http://purl.obolibrary.org/obo/GO_0032289 central nervous system myelin formation http://purl.obolibrary.org/obo/GO_0032288 myelin assembly The process in which the wraps of cell membrane that constitute myelin are laid down around an axon by an oligodendrocyte in the central nervous system. http://purl.obolibrary.org/obo/GO_0032290 peripheral nervous system myelin formation http://purl.obolibrary.org/obo/GO_0032288 myelin assembly The process in which the wraps of cell membrane that constitute myelin are laid down around an axon by Schwann cells in the peripheral nervous system. http://purl.obolibrary.org/obo/GO_0032291 axon ensheathment in central nervous system http://purl.obolibrary.org/obo/GO_0008366 axon ensheathment The process in which a glial cell membrane closes around an axon in the central nervous system. This can be a myelinating or a non-myelinating neuron-glial interaction. http://purl.obolibrary.org/obo/GO_0032292 peripheral nervous system axon ensheathment http://purl.obolibrary.org/obo/GO_0008366 axon ensheathment The process in which a Schwann cell membrane closes around an axon in the peripheral nervous system. This can be a myelinating or a non-myelinating neuron-glial interaction. http://purl.obolibrary.org/obo/GO_0032330 regulation of chondrocyte differentiation http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the frequency, rate or extent of chondrocyte differentiation. http://purl.obolibrary.org/obo/GO_0032331 negative regulation of chondrocyte differentiation http://purl.obolibrary.org/obo/GO_0061037 negative regulation of cartilage development Any process that stops, prevents, or reduces the frequency, rate or extent of chondrocyte differentiation. http://purl.obolibrary.org/obo/GO_0032332 positive regulation of chondrocyte differentiation http://purl.obolibrary.org/obo/GO_0045597 positive regulation of cell differentiation Any process that activates or increases the frequency, rate or extent of chondrocyte differentiation. http://purl.obolibrary.org/obo/GO_0032341 aldosterone metabolic process http://purl.obolibrary.org/obo/GO_0042180 ketone metabolic process The chemical reactions and pathways involving aldosterone, a corticosteroid hormone that is produced by the zona glomerulosa of the adrenal cortex and regulates salt (sodium and potassium) and water balance. http://purl.obolibrary.org/obo/GO_0032342 aldosterone biosynthetic process http://purl.obolibrary.org/obo/GO_0032341 aldosterone metabolic process The chemical reactions and pathways resulting in the formation of aldosterone, a corticosteroid hormone that is produced by the zona glomerulosa of the adrenal cortex and regulates salt (sodium and potassium) and water balance. http://purl.obolibrary.org/obo/GO_0032343 aldosterone catabolic process http://purl.obolibrary.org/obo/GO_0046185 aldehyde catabolic process The chemical reactions and pathways resulting in the breakdown of aldosterone, a corticosteroid hormone that is produced by the zona glomerulosa of the adrenal cortex and regulates salt (sodium and potassium) and water balance. http://purl.obolibrary.org/obo/GO_0032344 regulation of aldosterone metabolic process http://purl.obolibrary.org/obo/GO_0062012 regulation of small molecule metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving aldosterone. http://purl.obolibrary.org/obo/GO_0032347 regulation of aldosterone biosynthetic process http://purl.obolibrary.org/obo/GO_1902930 regulation of alcohol biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of aldosterone. http://purl.obolibrary.org/obo/GO_0032348 negative regulation of aldosterone biosynthetic process http://purl.obolibrary.org/obo/GO_1902931 negative regulation of alcohol biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of aldosterone. http://purl.obolibrary.org/obo/GO_0032349 positive regulation of aldosterone biosynthetic process http://purl.obolibrary.org/obo/GO_1902932 positive regulation of alcohol biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of aldosterone. http://purl.obolibrary.org/obo/GO_0032351 negative regulation of hormone metabolic process http://purl.obolibrary.org/obo/GO_0009892 negative regulation of metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving any hormone. http://purl.obolibrary.org/obo/GO_0032352 positive regulation of hormone metabolic process http://purl.obolibrary.org/obo/GO_0009893 positive regulation of metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving any hormone. http://purl.obolibrary.org/obo/GO_0032353 negative regulation of hormone biosynthetic process http://purl.obolibrary.org/obo/GO_0009890 negative regulation of biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hormones. http://purl.obolibrary.org/obo/GO_0032355 response to estradiol http://purl.obolibrary.org/obo/GO_0033993 response to lipid Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen. http://purl.obolibrary.org/obo/GO_0032364 intracellular oxygen homeostasis http://purl.obolibrary.org/obo/GO_0055082 intracellular chemical homeostasis A homeostatic process involved in the maintenance of a steady state level of oxygen within a cell. http://purl.obolibrary.org/obo/GO_0032369 negative regulation of lipid transport http://purl.obolibrary.org/obo/GO_1905953 negative regulation of lipid localization Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0032370 positive regulation of lipid transport http://purl.obolibrary.org/obo/GO_1905954 positive regulation of lipid localization Any process that activates or increases the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0032377 regulation of intracellular lipid transport http://purl.obolibrary.org/obo/GO_0032386 regulation of intracellular transport Any process that modulates the frequency, rate or extent of the directed movement of lipids within cells. http://purl.obolibrary.org/obo/GO_0032378 negative regulation of intracellular lipid transport http://purl.obolibrary.org/obo/GO_0032387 negative regulation of intracellular transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids within cells. http://purl.obolibrary.org/obo/GO_0032379 positive regulation of intracellular lipid transport http://purl.obolibrary.org/obo/GO_0032388 positive regulation of intracellular transport Any process that activates or increases the frequency, rate or extent of the directed movement of lipids within cells. http://purl.obolibrary.org/obo/GO_0032386 regulation of intracellular transport http://purl.obolibrary.org/obo/GO_0060341 regulation of cellular localization Any process that modulates the frequency, rate or extent of the directed movement of substances within cells. http://purl.obolibrary.org/obo/GO_0032387 negative regulation of intracellular transport http://purl.obolibrary.org/obo/GO_0051051 negative regulation of transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances within cells. http://purl.obolibrary.org/obo/GO_0032388 positive regulation of intracellular transport http://purl.obolibrary.org/obo/GO_0051050 positive regulation of transport Any process that activates or increases the frequency, rate or extent of the directed movement of substances within cells. http://purl.obolibrary.org/obo/GO_0032394 MHC class Ib receptor activity http://purl.obolibrary.org/obo/GO_0140375 immune receptor activity Combining with an MHC class Ib protein complex and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. Class Ib here refers to non-classical class I molecules, such as those of the CD1 or HLA-E gene families. http://purl.obolibrary.org/obo/GO_0032400 melanosome localization http://purl.obolibrary.org/obo/GO_0051875 pigment granule localization Any process in which a melanosome is transported to, and/or maintained in, a specific location within the cell. http://purl.obolibrary.org/obo/GO_0032401 establishment of melanosome localization http://purl.obolibrary.org/obo/GO_0051905 establishment of pigment granule localization The directed movement of a melanosome to a specific location. http://purl.obolibrary.org/obo/GO_0032402 melanosome transport http://purl.obolibrary.org/obo/GO_0051904 pigment granule transport The directed movement of melanosomes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0032410 negative regulation of transporter activity http://purl.obolibrary.org/obo/GO_0051051 negative regulation of transport Any process that stops or reduces the activity of a transporter. http://purl.obolibrary.org/obo/GO_0032411 positive regulation of transporter activity http://purl.obolibrary.org/obo/GO_0051050 positive regulation of transport Any process that activates or increases the activity of a transporter. http://purl.obolibrary.org/obo/GO_0032414 positive regulation of ion transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0034767 positive regulation of monoatomic ion transmembrane transport Any process that activates or increases the activity of an ion transporter. http://purl.obolibrary.org/obo/GO_0032418 lysosome localization http://purl.obolibrary.org/obo/GO_1990849 vacuolar localization Any process in which a lysosome is transported to, and/or maintained in, a specific location. http://purl.obolibrary.org/obo/GO_0032438 melanosome organization http://purl.obolibrary.org/obo/GO_0048753 pigment granule organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a melanosome. A melanosome is a tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored. http://purl.obolibrary.org/obo/GO_0032468 Golgi calcium ion homeostasis http://purl.obolibrary.org/obo/GO_0006874 intracellular calcium ion homeostasis Any process involved in the maintenance of an internal steady state of calcium ions within the Golgi apparatus of a cell or between the Golgi and its surroundings. http://purl.obolibrary.org/obo/GO_0032472 Golgi calcium ion transport http://purl.obolibrary.org/obo/GO_0006816 calcium ion transport The directed movement of calcium ions (Ca2+) into, out of or within the Golgi apparatus. http://purl.obolibrary.org/obo/GO_0032479 regulation of type I interferon production http://purl.obolibrary.org/obo/GO_0001817 regulation of cytokine production Any process that modulates the frequency, rate, or extent of interferon type I production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families. http://purl.obolibrary.org/obo/GO_0032480 negative regulation of type I interferon production http://purl.obolibrary.org/obo/GO_0032479 regulation of type I interferon production Any process that stops, prevents, or reduces the frequency, rate, or extent of type I interferon production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families. http://purl.obolibrary.org/obo/GO_0032481 positive regulation of type I interferon production http://purl.obolibrary.org/obo/GO_0032479 regulation of type I interferon production Any process that activates or increases the frequency, rate, or extent of type I interferon production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families. http://purl.obolibrary.org/obo/GO_0032528 microvillus organization http://purl.obolibrary.org/obo/GO_0120036 plasma membrane bounded cell projection organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microvillus, a thin cylindrical membrane-covered projection on the surface of a cell. http://purl.obolibrary.org/obo/GO_0032529 follicle cell microvillus organization http://purl.obolibrary.org/obo/GO_0032528 microvillus organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microvillus on a follicle cell. A microvillus is a thin cylindrical membrane-covered projection on the surface of an animal cell containing a core bundle of actin filaments. http://purl.obolibrary.org/obo/GO_0032530 regulation of microvillus organization http://purl.obolibrary.org/obo/GO_0120035 regulation of plasma membrane bounded cell projection organization Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a microvillus. http://purl.obolibrary.org/obo/GO_0032531 regulation of follicle cell microvillus organization http://purl.obolibrary.org/obo/GO_0032530 regulation of microvillus organization Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a microvillus on a follicle cell. http://purl.obolibrary.org/obo/GO_0032534 regulation of microvillus assembly http://purl.obolibrary.org/obo/GO_0120032 regulation of plasma membrane bounded cell projection assembly A process that modulates the formation of a microvillus. http://purl.obolibrary.org/obo/GO_0032543 mitochondrial translation http://purl.obolibrary.org/obo/GO_0006412 translation The chemical reactions and pathways resulting in the formation of a protein in a mitochondrion. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein; the mitochondrion has its own ribosomes and transfer RNAs, and uses a genetic code that differs from the nuclear code. http://purl.obolibrary.org/obo/GO_0032544 plastid translation http://purl.obolibrary.org/obo/GO_0009657 plastid organization The chemical reactions and pathways resulting in the formation of a protein in a plastid. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein; the plastid has its own ribosomes and transfer RNAs, and uses a genetic code that differs from the nuclear code. http://purl.obolibrary.org/obo/GO_0032555 purine ribonucleotide binding http://purl.obolibrary.org/obo/GO_0032553 ribonucleotide binding Binding to a purine ribonucleotide, any compound consisting of a purine ribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety. http://purl.obolibrary.org/obo/GO_0032570 response to progesterone http://purl.obolibrary.org/obo/GO_1901654 response to ketone Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a progesterone stimulus. http://purl.obolibrary.org/obo/GO_0032589 neuron projection membrane http://purl.obolibrary.org/obo/GO_0031256 leading edge membrane The portion of the plasma membrane surrounding a neuron projection. http://purl.obolibrary.org/obo/GO_0032590 dendrite membrane http://purl.obolibrary.org/obo/GO_0032589 neuron projection membrane The portion of the plasma membrane surrounding a dendrite. http://purl.obolibrary.org/obo/GO_0032594 protein transport within lipid bilayer http://purl.obolibrary.org/obo/GO_0006886 intracellular protein transport The directed movement of a protein from one location to another within a lipid bilayer. http://purl.obolibrary.org/obo/GO_0032606 type I interferon production http://purl.obolibrary.org/obo/GO_0001816 cytokine production The appearance of type I interferon due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families. http://purl.obolibrary.org/obo/GO_0032609 type II interferon production http://purl.obolibrary.org/obo/GO_0001816 cytokine production The appearance of interferon-gamma due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Interferon-gamma is also known as type II interferon. http://purl.obolibrary.org/obo/GO_0032611 interleukin-1 beta production http://purl.obolibrary.org/obo/GO_0032612 interleukin-1 production The appearance of interleukin-1 beta due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. http://purl.obolibrary.org/obo/GO_0032612 interleukin-1 production http://purl.obolibrary.org/obo/GO_0001816 cytokine production The appearance of interleukin-1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. http://purl.obolibrary.org/obo/GO_0032613 interleukin-10 production http://purl.obolibrary.org/obo/GO_0001816 cytokine production The appearance of interleukin-10 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. http://purl.obolibrary.org/obo/GO_0032616 interleukin-13 production http://purl.obolibrary.org/obo/GO_0001816 cytokine production The appearance of interleukin-13 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. http://purl.obolibrary.org/obo/GO_0032620 interleukin-17 production http://purl.obolibrary.org/obo/GO_0001816 cytokine production The appearance of any member of the interleukin-17 family of cytokines due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. http://purl.obolibrary.org/obo/GO_0032623 interleukin-2 production http://purl.obolibrary.org/obo/GO_0001816 cytokine production The appearance of interleukin-2 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. http://purl.obolibrary.org/obo/GO_0032626 interleukin-22 production http://purl.obolibrary.org/obo/GO_0001816 cytokine production The appearance of interleukin-22 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. http://purl.obolibrary.org/obo/GO_0032633 interleukin-4 production http://purl.obolibrary.org/obo/GO_0001816 cytokine production The appearance of interleukin-4 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. http://purl.obolibrary.org/obo/GO_0032634 interleukin-5 production http://purl.obolibrary.org/obo/GO_0001816 cytokine production The appearance of interleukin-5 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. http://purl.obolibrary.org/obo/GO_0032635 interleukin-6 production http://purl.obolibrary.org/obo/GO_0001816 cytokine production The appearance of interleukin-6 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. http://purl.obolibrary.org/obo/GO_0032637 interleukin-8 production http://purl.obolibrary.org/obo/GO_0001816 cytokine production The appearance of interleukin-8 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. http://purl.obolibrary.org/obo/GO_0032638 interleukin-9 production http://purl.obolibrary.org/obo/GO_0001816 cytokine production The appearance of interleukin-9 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. http://purl.obolibrary.org/obo/GO_0032640 tumor necrosis factor production http://purl.obolibrary.org/obo/GO_0071706 tumor necrosis factor superfamily cytokine production The appearance of tumor necrosis factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Tumor necrosis factor is an inflammatory cytokine produced by macrophages/monocytes during acute inflammation and which is responsible for a diverse range of signaling events within cells, leading to necrosis or apoptosis. http://purl.obolibrary.org/obo/GO_0032649 regulation of type II interferon production http://purl.obolibrary.org/obo/GO_0001817 regulation of cytokine production Any process that modulates the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon. http://purl.obolibrary.org/obo/GO_0032651 regulation of interleukin-1 beta production http://purl.obolibrary.org/obo/GO_0032652 regulation of interleukin-1 production Any process that modulates the frequency, rate, or extent of interleukin-1 beta production. http://purl.obolibrary.org/obo/GO_0032652 regulation of interleukin-1 production http://purl.obolibrary.org/obo/GO_0001817 regulation of cytokine production Any process that modulates the frequency, rate, or extent of interleukin-1 production. http://purl.obolibrary.org/obo/GO_0032653 regulation of interleukin-10 production http://purl.obolibrary.org/obo/GO_0001817 regulation of cytokine production Any process that modulates the frequency, rate, or extent of interleukin-10 production. http://purl.obolibrary.org/obo/GO_0032656 regulation of interleukin-13 production http://purl.obolibrary.org/obo/GO_0001817 regulation of cytokine production Any process that modulates the frequency, rate, or extent of interleukin-13 production. http://purl.obolibrary.org/obo/GO_0032660 regulation of interleukin-17 production http://purl.obolibrary.org/obo/GO_0001817 regulation of cytokine production Any process that modulates the frequency, rate, or extent of production of any member of the interleukin-17 family of cytokines. http://purl.obolibrary.org/obo/GO_0032663 regulation of interleukin-2 production http://purl.obolibrary.org/obo/GO_0001817 regulation of cytokine production Any process that modulates the frequency, rate, or extent of interleukin-2 production. http://purl.obolibrary.org/obo/GO_0032666 regulation of interleukin-22 production http://purl.obolibrary.org/obo/GO_0001817 regulation of cytokine production Any process that modulates the frequency, rate, or extent of interleukin-22 production. http://purl.obolibrary.org/obo/GO_0032673 regulation of interleukin-4 production http://purl.obolibrary.org/obo/GO_0001817 regulation of cytokine production Any process that modulates the frequency, rate, or extent of interleukin-4 production. http://purl.obolibrary.org/obo/GO_0032674 regulation of interleukin-5 production http://purl.obolibrary.org/obo/GO_0001817 regulation of cytokine production Any process that modulates the frequency, rate, or extent of interleukin-5 production. http://purl.obolibrary.org/obo/GO_0032675 regulation of interleukin-6 production http://purl.obolibrary.org/obo/GO_0001817 regulation of cytokine production Any process that modulates the frequency, rate, or extent of interleukin-6 production. http://purl.obolibrary.org/obo/GO_0032677 regulation of interleukin-8 production http://purl.obolibrary.org/obo/GO_0001817 regulation of cytokine production Any process that modulates the frequency, rate, or extent of interleukin-8 production. http://purl.obolibrary.org/obo/GO_0032678 regulation of interleukin-9 production http://purl.obolibrary.org/obo/GO_0001817 regulation of cytokine production Any process that modulates the frequency, rate, or extent of interleukin-9 production. http://purl.obolibrary.org/obo/GO_0032680 regulation of tumor necrosis factor production http://purl.obolibrary.org/obo/GO_1903555 regulation of tumor necrosis factor superfamily cytokine production Any process that modulates the frequency, rate or extent of tumor necrosis factor production. http://purl.obolibrary.org/obo/GO_0032689 negative regulation of type II interferon production http://purl.obolibrary.org/obo/GO_0032649 regulation of type II interferon production Any process that stops, prevents, or reduces the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon. http://purl.obolibrary.org/obo/GO_0032691 negative regulation of interleukin-1 beta production http://purl.obolibrary.org/obo/GO_0032692 negative regulation of interleukin-1 production Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-1 beta production. http://purl.obolibrary.org/obo/GO_0032692 negative regulation of interleukin-1 production http://purl.obolibrary.org/obo/GO_0032652 regulation of interleukin-1 production Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-1 production. http://purl.obolibrary.org/obo/GO_0032693 negative regulation of interleukin-10 production http://purl.obolibrary.org/obo/GO_0032653 regulation of interleukin-10 production Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-10 production. http://purl.obolibrary.org/obo/GO_0032696 negative regulation of interleukin-13 production http://purl.obolibrary.org/obo/GO_0032656 regulation of interleukin-13 production Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-13 production. http://purl.obolibrary.org/obo/GO_0032700 negative regulation of interleukin-17 production http://purl.obolibrary.org/obo/GO_0032660 regulation of interleukin-17 production Any process that stops, prevents, or reduces the frequency, rate, or extent of production of any member of the interleukin-17 family of cytokines. http://purl.obolibrary.org/obo/GO_0032703 negative regulation of interleukin-2 production http://purl.obolibrary.org/obo/GO_0032663 regulation of interleukin-2 production Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-2 production. http://purl.obolibrary.org/obo/GO_0032706 negative regulation of interleukin-22 production http://purl.obolibrary.org/obo/GO_0032666 regulation of interleukin-22 production Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-22 production. http://purl.obolibrary.org/obo/GO_0032713 negative regulation of interleukin-4 production http://purl.obolibrary.org/obo/GO_0032673 regulation of interleukin-4 production Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-4 production. http://purl.obolibrary.org/obo/GO_0032714 negative regulation of interleukin-5 production http://purl.obolibrary.org/obo/GO_0032674 regulation of interleukin-5 production Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-5 production. http://purl.obolibrary.org/obo/GO_0032715 negative regulation of interleukin-6 production http://purl.obolibrary.org/obo/GO_0032675 regulation of interleukin-6 production Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-6 production. http://purl.obolibrary.org/obo/GO_0032717 negative regulation of interleukin-8 production http://purl.obolibrary.org/obo/GO_0032677 regulation of interleukin-8 production Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-8 production. http://purl.obolibrary.org/obo/GO_0032718 negative regulation of interleukin-9 production http://purl.obolibrary.org/obo/GO_0032678 regulation of interleukin-9 production Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-9 production. http://purl.obolibrary.org/obo/GO_0032720 negative regulation of tumor necrosis factor production http://purl.obolibrary.org/obo/GO_1903556 negative regulation of tumor necrosis factor superfamily cytokine production Any process that stops, prevents, or reduces the frequency, rate, or extent of tumor necrosis factor production. http://purl.obolibrary.org/obo/GO_0032729 positive regulation of type II interferon production http://purl.obolibrary.org/obo/GO_0032649 regulation of type II interferon production Any process that activates or increases the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon. http://purl.obolibrary.org/obo/GO_0032731 positive regulation of interleukin-1 beta production http://purl.obolibrary.org/obo/GO_0032732 positive regulation of interleukin-1 production Any process that activates or increases the frequency, rate, or extent of interleukin-1 beta production. http://purl.obolibrary.org/obo/GO_0032732 positive regulation of interleukin-1 production http://purl.obolibrary.org/obo/GO_0032652 regulation of interleukin-1 production Any process that activates or increases the frequency, rate, or extent of interleukin-1 production. http://purl.obolibrary.org/obo/GO_0032733 positive regulation of interleukin-10 production http://purl.obolibrary.org/obo/GO_0032653 regulation of interleukin-10 production Any process that activates or increases the frequency, rate, or extent of interleukin-10 production. http://purl.obolibrary.org/obo/GO_0032736 positive regulation of interleukin-13 production http://purl.obolibrary.org/obo/GO_0032656 regulation of interleukin-13 production Any process that activates or increases the frequency, rate, or extent of interleukin-13 production. http://purl.obolibrary.org/obo/GO_0032740 positive regulation of interleukin-17 production http://purl.obolibrary.org/obo/GO_0032660 regulation of interleukin-17 production Any process that activates or increases the frequency, rate, or extent of production of any member of the interleukin-17 family of cytokines. http://purl.obolibrary.org/obo/GO_0032743 positive regulation of interleukin-2 production http://purl.obolibrary.org/obo/GO_0032663 regulation of interleukin-2 production Any process that activates or increases the frequency, rate, or extent of interleukin-2 production. http://purl.obolibrary.org/obo/GO_0032746 positive regulation of interleukin-22 production http://purl.obolibrary.org/obo/GO_0032666 regulation of interleukin-22 production Any process that activates or increases the frequency, rate, or extent of interleukin-22 production. http://purl.obolibrary.org/obo/GO_0032753 positive regulation of interleukin-4 production http://purl.obolibrary.org/obo/GO_0032673 regulation of interleukin-4 production Any process that activates or increases the frequency, rate, or extent of interleukin-4 production. http://purl.obolibrary.org/obo/GO_0032754 positive regulation of interleukin-5 production http://purl.obolibrary.org/obo/GO_0032674 regulation of interleukin-5 production Any process that activates or increases the frequency, rate, or extent of interleukin-5 production. http://purl.obolibrary.org/obo/GO_0032755 positive regulation of interleukin-6 production http://purl.obolibrary.org/obo/GO_0032675 regulation of interleukin-6 production Any process that activates or increases the frequency, rate, or extent of interleukin-6 production. http://purl.obolibrary.org/obo/GO_0032757 positive regulation of interleukin-8 production http://purl.obolibrary.org/obo/GO_0032677 regulation of interleukin-8 production Any process that activates or increases the frequency, rate, or extent of interleukin-8 production. http://purl.obolibrary.org/obo/GO_0032758 positive regulation of interleukin-9 production http://purl.obolibrary.org/obo/GO_0032678 regulation of interleukin-9 production Any process that activates or increases the frequency, rate, or extent of interleukin-9 production. http://purl.obolibrary.org/obo/GO_0032760 positive regulation of tumor necrosis factor production http://purl.obolibrary.org/obo/GO_1903557 positive regulation of tumor necrosis factor superfamily cytokine production Any process that activates or increases the frequency, rate or extent of tumor necrosis factor production. http://purl.obolibrary.org/obo/GO_0032762 mast cell cytokine production http://purl.obolibrary.org/obo/GO_0061082 myeloid leukocyte cytokine production Any process that contributes to cytokine production by a mast cell. http://purl.obolibrary.org/obo/GO_0032763 regulation of mast cell cytokine production http://purl.obolibrary.org/obo/GO_0002718 regulation of cytokine production involved in immune response Any process that modulates the frequency, rate, or extent of mast cell cytokine production. http://purl.obolibrary.org/obo/GO_0032764 negative regulation of mast cell cytokine production http://purl.obolibrary.org/obo/GO_0032763 regulation of mast cell cytokine production Any process that stops, prevents, or reduces the frequency, rate, or extent of mast cell cytokine production. http://purl.obolibrary.org/obo/GO_0032765 positive regulation of mast cell cytokine production http://purl.obolibrary.org/obo/GO_0032763 regulation of mast cell cytokine production Any process that activates or increases the frequency, rate, or extent of mast cell cytokine production. http://purl.obolibrary.org/obo/GO_0032780 negative regulation of ATP-dependent activity http://purl.obolibrary.org/obo/GO_0043462 regulation of ATP-dependent activity Any process that stops or reduces the rate of an ATP-dependent activity. http://purl.obolibrary.org/obo/GO_0032790 ribosome disassembly http://purl.obolibrary.org/obo/GO_1903008 organelle disassembly The disaggregation of a ribosome into its constituent components; includes the dissociation of ribosomal subunits. http://purl.obolibrary.org/obo/GO_0032808 lacrimal gland development http://purl.obolibrary.org/obo/GO_0048732 gland development The process whose specific outcome is the progression of the lacrimal gland over time, from its formation to the mature structure. The lacrimal gland produces secretions that lubricate and protect the cornea of the eye. http://purl.obolibrary.org/obo/GO_0032811 negative regulation of epinephrine secretion http://purl.obolibrary.org/obo/GO_0033604 negative regulation of catecholamine secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of epinephrine. http://purl.obolibrary.org/obo/GO_0032812 positive regulation of epinephrine secretion http://purl.obolibrary.org/obo/GO_0033605 positive regulation of catecholamine secretion Any process that activates or increases the frequency, rate or extent of the regulated release of epinephrine. http://purl.obolibrary.org/obo/GO_0032814 regulation of natural killer cell activation http://purl.obolibrary.org/obo/GO_0051249 regulation of lymphocyte activation Any process that modulates the frequency, rate or extent of natural killer cell activation. http://purl.obolibrary.org/obo/GO_0032815 negative regulation of natural killer cell activation http://purl.obolibrary.org/obo/GO_0051250 negative regulation of lymphocyte activation Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell activation. http://purl.obolibrary.org/obo/GO_0032816 positive regulation of natural killer cell activation http://purl.obolibrary.org/obo/GO_0051251 positive regulation of lymphocyte activation Any process that activates or increases the frequency, rate or extent of natural killer cell activation. http://purl.obolibrary.org/obo/GO_0032817 regulation of natural killer cell proliferation http://purl.obolibrary.org/obo/GO_0050670 regulation of lymphocyte proliferation Any process that modulates the frequency, rate or extent of natural killer cell proliferation. http://purl.obolibrary.org/obo/GO_0032818 negative regulation of natural killer cell proliferation http://purl.obolibrary.org/obo/GO_0050672 negative regulation of lymphocyte proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell proliferation. http://purl.obolibrary.org/obo/GO_0032819 positive regulation of natural killer cell proliferation http://purl.obolibrary.org/obo/GO_0050671 positive regulation of lymphocyte proliferation Any process that activates or increases the frequency, rate or extent of natural killer cell proliferation. http://purl.obolibrary.org/obo/GO_0032823 regulation of natural killer cell differentiation http://purl.obolibrary.org/obo/GO_0045619 regulation of lymphocyte differentiation Any process that modulates the frequency, rate or extent of natural killer cell differentiation. http://purl.obolibrary.org/obo/GO_0032824 negative regulation of natural killer cell differentiation http://purl.obolibrary.org/obo/GO_0045620 negative regulation of lymphocyte differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell differentiation. http://purl.obolibrary.org/obo/GO_0032825 positive regulation of natural killer cell differentiation http://purl.obolibrary.org/obo/GO_0045621 positive regulation of lymphocyte differentiation Any process that activates or increases the frequency, rate or extent of natural killer cell differentiation. http://purl.obolibrary.org/obo/GO_0032829 regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation http://purl.obolibrary.org/obo/GO_0045589 regulation of regulatory T cell differentiation Any process that modulates the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells. http://purl.obolibrary.org/obo/GO_0032830 negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation http://purl.obolibrary.org/obo/GO_0045590 negative regulation of regulatory T cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells. http://purl.obolibrary.org/obo/GO_0032831 positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation http://purl.obolibrary.org/obo/GO_0045591 positive regulation of regulatory T cell differentiation Any process that activates or increases the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells. http://purl.obolibrary.org/obo/GO_0032835 glomerulus development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the vertebrate kidney. The glomerulus is part of the nephron and is restricted to one body segment. http://purl.obolibrary.org/obo/GO_0032836 glomerular basement membrane development http://purl.obolibrary.org/obo/GO_0030198 extracellular matrix organization The process whose specific outcome is the progression of the glomerular basement membrane over time, from its formation to the mature structure. The glomerular basement membrane is the basal laminal portion of the glomerulus which performs the actual filtration. http://purl.obolibrary.org/obo/GO_0032839 dendrite cytoplasm http://purl.obolibrary.org/obo/GO_0120111 neuron projection cytoplasm All of the contents of a dendrite, excluding the surrounding plasma membrane. http://purl.obolibrary.org/obo/GO_0032868 response to insulin http://purl.obolibrary.org/obo/GO_0043434 response to peptide hormone Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms. http://purl.obolibrary.org/obo/GO_0032871 regulation of karyogamy http://purl.obolibrary.org/obo/GO_1903353 regulation of nucleus organization Any process that modulates the frequency, rate or extent of karyogamy, the creation of a single nucleus from multiple nuclei as a result of membrane fusion. http://purl.obolibrary.org/obo/GO_0032878 regulation of establishment or maintenance of cell polarity http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns. http://purl.obolibrary.org/obo/GO_0032880 regulation of protein localization http://purl.obolibrary.org/obo/GO_0032879 regulation of localization Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location. http://purl.obolibrary.org/obo/GO_0032881 regulation of polysaccharide metabolic process http://purl.obolibrary.org/obo/GO_0060255 regulation of macromolecule metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving polysaccharides. http://purl.obolibrary.org/obo/GO_0032886 regulation of microtubule-based process http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the microtubule cytoskeleton. http://purl.obolibrary.org/obo/GO_0032890 regulation of organic acid transport http://purl.obolibrary.org/obo/GO_0051049 regulation of transport Any process that modulates the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0032891 negative regulation of organic acid transport http://purl.obolibrary.org/obo/GO_0051051 negative regulation of transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0032892 positive regulation of organic acid transport http://purl.obolibrary.org/obo/GO_0051050 positive regulation of transport Any process that activates or increases the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0032928 regulation of superoxide anion generation http://purl.obolibrary.org/obo/GO_0090322 regulation of superoxide metabolic process Any process that modulates the frequency, rate or extent of enzymatic generation of superoxide by a cell. http://purl.obolibrary.org/obo/GO_0032929 negative regulation of superoxide anion generation http://purl.obolibrary.org/obo/GO_2000378 negative regulation of reactive oxygen species metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of enzymatic generation of superoxide by a cell. http://purl.obolibrary.org/obo/GO_0032930 positive regulation of superoxide anion generation http://purl.obolibrary.org/obo/GO_2000379 positive regulation of reactive oxygen species metabolic process Any process that activates or increases the frequency, rate or extent of enzymatic generation of superoxide by a cell. http://purl.obolibrary.org/obo/GO_0032938 negative regulation of translation in response to oxidative stress http://purl.obolibrary.org/obo/GO_0043558 regulation of translational initiation in response to stress Any process that stops, prevents, or reduces the frequency, rate or extent of translation as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals. http://purl.obolibrary.org/obo/GO_0032939 positive regulation of translation in response to oxidative stress http://purl.obolibrary.org/obo/GO_0032056 positive regulation of translation in response to stress Any process that activates or increases the frequency, rate or extent of translation as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals. http://purl.obolibrary.org/obo/GO_0032941 secretion by tissue http://purl.obolibrary.org/obo/GO_0046903 secretion The controlled release of a substance by a tissue. http://purl.obolibrary.org/obo/GO_0032943 mononuclear cell proliferation http://purl.obolibrary.org/obo/GO_0070661 leukocyte proliferation The expansion of a mononuclear cell population by cell division. A mononuclear cell is a leukocyte with a single non-segmented nucleus in the mature form. http://purl.obolibrary.org/obo/GO_0032944 regulation of mononuclear cell proliferation http://purl.obolibrary.org/obo/GO_0070663 regulation of leukocyte proliferation Any process that modulates the frequency, rate or extent of mononuclear cell proliferation. http://purl.obolibrary.org/obo/GO_0032945 negative regulation of mononuclear cell proliferation http://purl.obolibrary.org/obo/GO_0070664 negative regulation of leukocyte proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of mononuclear cell proliferation. http://purl.obolibrary.org/obo/GO_0032946 positive regulation of mononuclear cell proliferation http://purl.obolibrary.org/obo/GO_0070665 positive regulation of leukocyte proliferation Any process that activates or increases the frequency, rate or extent of mononuclear cell proliferation. http://purl.obolibrary.org/obo/GO_0032956 regulation of actin cytoskeleton organization http://purl.obolibrary.org/obo/GO_0032970 regulation of actin filament-based process Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins. http://purl.obolibrary.org/obo/GO_0032964 collagen biosynthetic process http://purl.obolibrary.org/obo/GO_0032963 collagen metabolic process The chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%). http://purl.obolibrary.org/obo/GO_0032965 regulation of collagen biosynthetic process http://purl.obolibrary.org/obo/GO_0010712 regulation of collagen metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. http://purl.obolibrary.org/obo/GO_0032966 negative regulation of collagen biosynthetic process http://purl.obolibrary.org/obo/GO_0010713 negative regulation of collagen metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. http://purl.obolibrary.org/obo/GO_0032967 positive regulation of collagen biosynthetic process http://purl.obolibrary.org/obo/GO_0010714 positive regulation of collagen metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. http://purl.obolibrary.org/obo/GO_0032970 regulation of actin filament-based process http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the actin cytoskeleton. http://purl.obolibrary.org/obo/GO_0032973 amino acid export across plasma membrane http://purl.obolibrary.org/obo/GO_0140115 export across plasma membrane The directed movement of amino acids from inside of a cell, across the plasma membrane and into the extracellular region. http://purl.obolibrary.org/obo/GO_0032974 amino acid transmembrane export from vacuole http://purl.obolibrary.org/obo/GO_0034486 vacuolar transmembrane transport The directed movement of amino acids out of the vacuole, across the vacuolar membrane. http://purl.obolibrary.org/obo/GO_0032975 amino acid transmembrane import into vacuole http://purl.obolibrary.org/obo/GO_0034486 vacuolar transmembrane transport The directed movement of amino acids into the vacuole across the vacuolar membrane. http://purl.obolibrary.org/obo/GO_0032980 keratinocyte activation http://purl.obolibrary.org/obo/GO_0001775 cell activation A change in the morphology or behavior of a keratinocyte resulting from exposure to an activating factor such as a cellular or soluble ligand. Upon activation, keratinocytes become migratory and hyperproliferative, and produce growth factors and cytokines. http://purl.obolibrary.org/obo/GO_0032983 kainate selective glutamate receptor complex http://purl.obolibrary.org/obo/GO_0008328 ionotropic glutamate receptor complex An assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex. Kainate receptors are multimeric assemblies of GluK1-3 (also called GluR5-7), GluK4 (KA1) and GluK5 (KA2) subunits. http://purl.obolibrary.org/obo/GO_0032987 protein-lipid complex disassembly http://purl.obolibrary.org/obo/GO_0071825 protein-lipid complex organization The disaggregation of a protein-lipid complex into its constituent components. http://purl.obolibrary.org/obo/GO_0032994 protein-lipid complex http://purl.obolibrary.org/obo/GO_0032991 protein-containing complex A macromolecular complex containing separate protein and lipid molecules. Separate in this context means not covalently bound to each other. http://purl.obolibrary.org/obo/GO_0032997 Fc receptor complex http://purl.obolibrary.org/obo/GO_0098797 plasma membrane protein complex A protein complex composed of a subunit or subunits capable of binding the Fc portion of an immunoglobulin with additional signaling components. The complex functions as a receptor for immunoglobulin. http://purl.obolibrary.org/obo/GO_0033001 Fc-gamma receptor III complex http://purl.obolibrary.org/obo/GO_0032997 Fc receptor complex A protein complex composed of an Fc-gamma RIII alpha chain and an Fc-epsilon RI gamma chain dimer with or without an Fc-epsilon RI beta chain and additional signaling components. The complex functions primarily as an activating receptor for IgG. http://purl.obolibrary.org/obo/GO_0033003 regulation of mast cell activation http://purl.obolibrary.org/obo/GO_0002694 regulation of leukocyte activation Any process that modulates the frequency, rate, or extent of mast cell activation. http://purl.obolibrary.org/obo/GO_0033004 negative regulation of mast cell activation http://purl.obolibrary.org/obo/GO_0033003 regulation of mast cell activation Any process that stops, prevents, or reduces the frequency, rate, or extent of mast cell activation. http://purl.obolibrary.org/obo/GO_0033005 positive regulation of mast cell activation http://purl.obolibrary.org/obo/GO_0033003 regulation of mast cell activation Any process that activates or increases the frequency, rate, or extent of mast cell activation. http://purl.obolibrary.org/obo/GO_0033007 negative regulation of mast cell activation involved in immune response http://purl.obolibrary.org/obo/GO_0033004 negative regulation of mast cell activation Any process that stops, prevents, or reduces the frequency, rate, or extent of mast cell activation as part of an immune response. http://purl.obolibrary.org/obo/GO_0033008 positive regulation of mast cell activation involved in immune response http://purl.obolibrary.org/obo/GO_0033005 positive regulation of mast cell activation Any process that activates or increases the frequency, rate, or extent of mast cell activation as part of an immune response. http://purl.obolibrary.org/obo/GO_0033023 mast cell homeostasis http://purl.obolibrary.org/obo/GO_0002262 myeloid cell homeostasis The process of regulating the proliferation and elimination of mast cells such that the total number of mast cells within a whole or part of an organism is stable over time in the absence of an outside stimulus. http://purl.obolibrary.org/obo/GO_0033024 mast cell apoptotic process http://purl.obolibrary.org/obo/GO_0071887 leukocyte apoptotic process Any apoptotic process in a mast cell, a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation. http://purl.obolibrary.org/obo/GO_0033025 regulation of mast cell apoptotic process http://purl.obolibrary.org/obo/GO_2000106 regulation of leukocyte apoptotic process Any process that modulates the frequency, rate, or extent of mast cell apoptotic process. http://purl.obolibrary.org/obo/GO_0033026 negative regulation of mast cell apoptotic process http://purl.obolibrary.org/obo/GO_2000107 negative regulation of leukocyte apoptotic process Any process that stops, prevents, or reduces the frequency, rate, or extent of mast cell apoptotic process. http://purl.obolibrary.org/obo/GO_0033027 positive regulation of mast cell apoptotic process http://purl.obolibrary.org/obo/GO_2000108 positive regulation of leukocyte apoptotic process Any process that activates or increases the frequency, rate, or extent of mast cell apoptotic process. http://purl.obolibrary.org/obo/GO_0033029 regulation of neutrophil apoptotic process http://purl.obolibrary.org/obo/GO_2000106 regulation of leukocyte apoptotic process Any process that modulates the frequency, rate, or extent of neutrophil apoptotic process. http://purl.obolibrary.org/obo/GO_0033030 negative regulation of neutrophil apoptotic process http://purl.obolibrary.org/obo/GO_2000107 negative regulation of leukocyte apoptotic process Any process that stops, prevents, or reduces the frequency, rate, or extent of neutrophil apoptotic process. http://purl.obolibrary.org/obo/GO_0033031 positive regulation of neutrophil apoptotic process http://purl.obolibrary.org/obo/GO_2000108 positive regulation of leukocyte apoptotic process Any process that activates or increases the frequency, rate, or extent of neutrophil apoptotic process. http://purl.obolibrary.org/obo/GO_0033032 regulation of myeloid cell apoptotic process http://purl.obolibrary.org/obo/GO_0042981 regulation of apoptotic process Any process that modulates the frequency, rate, or extent of myeloid cell apoptotic process. http://purl.obolibrary.org/obo/GO_0033033 negative regulation of myeloid cell apoptotic process http://purl.obolibrary.org/obo/GO_0033032 regulation of myeloid cell apoptotic process Any process that stops, prevents, or reduces the frequency, rate, or extent of a myeloid cell apoptotic process. http://purl.obolibrary.org/obo/GO_0033034 positive regulation of myeloid cell apoptotic process http://purl.obolibrary.org/obo/GO_0043065 positive regulation of apoptotic process Any process that activates or increases the frequency, rate, or extent of myeloid cell apoptotic process. http://purl.obolibrary.org/obo/GO_0033044 regulation of chromosome organization http://purl.obolibrary.org/obo/GO_0033043 regulation of organelle organization Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a chromosome. http://purl.obolibrary.org/obo/GO_0033046 negative regulation of sister chromatid segregation http://purl.obolibrary.org/obo/GO_2001251 negative regulation of chromosome organization Any process that stops, prevents, or reduces the frequency, rate or extent of sister chromatid segregation. http://purl.obolibrary.org/obo/GO_0033048 negative regulation of mitotic sister chromatid segregation http://purl.obolibrary.org/obo/GO_0033047 regulation of mitotic sister chromatid segregation Any process that stops, prevents, or reduces the frequency, rate or extent of sister chromatid segregation during mitosis. http://purl.obolibrary.org/obo/GO_0033059 cellular pigmentation http://purl.obolibrary.org/obo/GO_0043473 pigmentation The deposition or aggregation of coloring matter in a cell. http://purl.obolibrary.org/obo/GO_0033077 T cell differentiation in thymus http://purl.obolibrary.org/obo/GO_0030217 T cell differentiation The process in which a precursor cell type acquires the specialized features of a T cell via a differentiation pathway dependent upon transit through the thymus. http://purl.obolibrary.org/obo/GO_0033079 immature T cell proliferation http://purl.obolibrary.org/obo/GO_0042098 T cell proliferation The expansion of an immature T cell population by cell division. http://purl.obolibrary.org/obo/GO_0033080 immature T cell proliferation in thymus http://purl.obolibrary.org/obo/GO_0033079 immature T cell proliferation The expansion of an immature T cell population by cell division in the thymus. http://purl.obolibrary.org/obo/GO_0033081 regulation of T cell differentiation in thymus http://purl.obolibrary.org/obo/GO_0045580 regulation of T cell differentiation Any process that modulates the frequency, rate or extent of T cell differentiation in the thymus. http://purl.obolibrary.org/obo/GO_0033083 regulation of immature T cell proliferation http://purl.obolibrary.org/obo/GO_0042129 regulation of T cell proliferation Any process that modulates the frequency, rate or extent of immature T cell proliferation. http://purl.obolibrary.org/obo/GO_0033084 regulation of immature T cell proliferation in thymus http://purl.obolibrary.org/obo/GO_0033083 regulation of immature T cell proliferation Any process that modulates the frequency, rate or extent of immature T cell proliferation in the thymus. http://purl.obolibrary.org/obo/GO_0033085 negative regulation of T cell differentiation in thymus http://purl.obolibrary.org/obo/GO_0045581 negative regulation of T cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of T cell differentiation in the thymus. http://purl.obolibrary.org/obo/GO_0033087 negative regulation of immature T cell proliferation http://purl.obolibrary.org/obo/GO_0042130 negative regulation of T cell proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of immature T cell proliferation. http://purl.obolibrary.org/obo/GO_0033088 negative regulation of immature T cell proliferation in thymus http://purl.obolibrary.org/obo/GO_0033087 negative regulation of immature T cell proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of immature T cell proliferation in the thymus. http://purl.obolibrary.org/obo/GO_0033089 positive regulation of T cell differentiation in thymus http://purl.obolibrary.org/obo/GO_0045582 positive regulation of T cell differentiation Any process that activates or increases the frequency, rate or extent of T cell differentiation in the thymus. http://purl.obolibrary.org/obo/GO_0033091 positive regulation of immature T cell proliferation http://purl.obolibrary.org/obo/GO_0042102 positive regulation of T cell proliferation Any process that activates or increases the frequency, rate or extent of immature T cell proliferation. http://purl.obolibrary.org/obo/GO_0033092 positive regulation of immature T cell proliferation in thymus http://purl.obolibrary.org/obo/GO_0033091 positive regulation of immature T cell proliferation Any process that activates or increases the frequency, rate or extent of immature T cell proliferation in the thymus. http://purl.obolibrary.org/obo/GO_0033093 Weibel-Palade body http://purl.obolibrary.org/obo/GO_0030136 clathrin-coated vesicle A large, elongated, rod-shaped secretory granule characteristic of vascular endothelial cells that contain a number of structurally and functionally distinct proteins, of which the best characterized are von Willebrand factor (VWF) and P-selectin. Weibel-Palade bodies are formed from the trans-Golgi network in a process that depends on VWF, which is densely packed in a highly organized manner, and on coat proteins that remain associated with the granules. Upon cell stimulation, regulated exocytosis releases the contained proteins to the cell surface, where they act in the recruitment of platelets and leukocytes and in inflammatory and vasoactive responses. http://purl.obolibrary.org/obo/GO_0033121 regulation of purine nucleotide catabolic process http://purl.obolibrary.org/obo/GO_1900542 regulation of purine nucleotide metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of purine nucleotides. http://purl.obolibrary.org/obo/GO_0033122 negative regulation of purine nucleotide catabolic process http://purl.obolibrary.org/obo/GO_1900543 negative regulation of purine nucleotide metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of purine nucleotides. http://purl.obolibrary.org/obo/GO_0033123 positive regulation of purine nucleotide catabolic process http://purl.obolibrary.org/obo/GO_1900544 positive regulation of purine nucleotide metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of purine nucleotides. http://purl.obolibrary.org/obo/GO_0033151 V(D)J recombination http://purl.obolibrary.org/obo/GO_0002562 somatic diversification of immune receptors via germline recombination within a single locus The process in which immune receptor V, D, and J, or V and J gene segments, depending on the specific receptor, are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS). http://purl.obolibrary.org/obo/GO_0033152 immunoglobulin V(D)J recombination http://purl.obolibrary.org/obo/GO_0033151 V(D)J recombination The process in which immunoglobulin gene segments are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS). For immunoglobulin heavy chains V, D, and J gene segments are joined, and for immunoglobulin light chains V and J gene segments are joined. http://purl.obolibrary.org/obo/GO_0033157 regulation of intracellular protein transport http://purl.obolibrary.org/obo/GO_0051223 regulation of protein transport Any process that modulates the frequency, rate or extent of the directed movement of proteins within cells. http://purl.obolibrary.org/obo/GO_0033162 melanosome membrane http://purl.obolibrary.org/obo/GO_0090741 pigment granule membrane The lipid bilayer surrounding a melanosome. http://purl.obolibrary.org/obo/GO_0033198 response to ATP http://purl.obolibrary.org/obo/GO_0014074 response to purine-containing compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ATP (adenosine 5'-triphosphate) stimulus. http://purl.obolibrary.org/obo/GO_0033212 iron import into cell http://purl.obolibrary.org/obo/GO_0051649 establishment of localization in cell The directed movement of iron ions from outside of a cell into the cytoplasmic compartment. This may occur via transport across the plasma membrane or via endocytosis. http://purl.obolibrary.org/obo/GO_0033239 negative regulation of amine metabolic process http://purl.obolibrary.org/obo/GO_0009892 negative regulation of metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amines. http://purl.obolibrary.org/obo/GO_0033240 positive regulation of amine metabolic process http://purl.obolibrary.org/obo/GO_0009893 positive regulation of metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amines. http://purl.obolibrary.org/obo/GO_0033241 regulation of amine catabolic process http://purl.obolibrary.org/obo/GO_0009894 regulation of catabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines. http://purl.obolibrary.org/obo/GO_0033242 negative regulation of amine catabolic process http://purl.obolibrary.org/obo/GO_0009895 negative regulation of catabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines. http://purl.obolibrary.org/obo/GO_0033243 positive regulation of amine catabolic process http://purl.obolibrary.org/obo/GO_0009896 positive regulation of catabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines. http://purl.obolibrary.org/obo/GO_0033278 cell proliferation in midbrain http://purl.obolibrary.org/obo/GO_0061351 neural precursor cell proliferation The multiplication or reproduction of cells, resulting in the expansion of a cell population in the midbrain. http://purl.obolibrary.org/obo/GO_0033326 cerebrospinal fluid secretion http://purl.obolibrary.org/obo/GO_0032941 secretion by tissue The regulated release of cerebrospinal fluid (CSF) from the choroid plexus of the lateral, third and fourth ventricles. The cerebrospinal fluid is a clear liquid that located within the ventricles, spinal canal, and subarachnoid spaces. http://purl.obolibrary.org/obo/GO_0033327 Leydig cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a Leydig cell. A Leydig cell is a testosterone-secreting cell in the interstitial area, between the seminiferous tubules, in the testis. http://purl.obolibrary.org/obo/GO_0033364 mast cell secretory granule organization http://purl.obolibrary.org/obo/GO_0033363 secretory granule organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule in a mast cell. A secretory granule is a small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. http://purl.obolibrary.org/obo/GO_0033365 protein localization to organelle http://purl.obolibrary.org/obo/GO_0008104 intracellular protein localization A process in which a protein is transported to, or maintained in, a location within an organelle. http://purl.obolibrary.org/obo/GO_0033366 protein localization to secretory granule http://purl.obolibrary.org/obo/GO_0033365 protein localization to organelle A process in which a protein is transported to, or maintained in, a location within a secretory granule. http://purl.obolibrary.org/obo/GO_0033371 T cell secretory granule organization http://purl.obolibrary.org/obo/GO_0033363 secretory granule organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule in a T cell. A secretory granule is a small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. http://purl.obolibrary.org/obo/GO_0033374 protein localization to T cell secretory granule http://purl.obolibrary.org/obo/GO_0033366 protein localization to secretory granule A process in which a protein is transported to, or maintained in, a location within a secretory granule in a T cell. http://purl.obolibrary.org/obo/GO_0033375 protease localization to T cell secretory granule http://purl.obolibrary.org/obo/GO_0033374 protein localization to T cell secretory granule Any process in which a protease is transported to, or maintained in, a location within a secretory granule in a T cell. http://purl.obolibrary.org/obo/GO_0033380 granzyme B localization to T cell secretory granule http://purl.obolibrary.org/obo/GO_0033375 protease localization to T cell secretory granule Any process in which the protease granzyme B is transported to, or maintained in, a location within a secretory granule in a T cell. http://purl.obolibrary.org/obo/GO_0033484 intracellular nitric oxide homeostasis http://purl.obolibrary.org/obo/GO_0055082 intracellular chemical homeostasis A homeostatic process involved in the maintenance of a steady state level of nitric oxide within a cell. http://purl.obolibrary.org/obo/GO_0033500 carbohydrate homeostasis http://purl.obolibrary.org/obo/GO_0048878 chemical homeostasis A homeostatic process involved in the maintenance of an internal steady state of a carbohydrate within an organism or cell. http://purl.obolibrary.org/obo/GO_0033504 floor plate development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the floor plate over time from its initial formation until its mature state. http://purl.obolibrary.org/obo/GO_0033505 floor plate morphogenesis http://purl.obolibrary.org/obo/GO_0048729 tissue morphogenesis The process in which the anatomical structure of the floor plate is generated and organized. http://purl.obolibrary.org/obo/GO_0033568 lactoferrin receptor activity http://purl.obolibrary.org/obo/GO_0038024 cargo receptor activity Combining with lactoferrin and delivering lactoferrin into the cell via endocytosis. Lactoferrin is an iron-binding glycoprotein which binds ferric iron most efficiently at low pH. http://purl.obolibrary.org/obo/GO_0033569 lactoferrin transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0008320 protein transmembrane transporter activity Enables the transfer of lactoferrin from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0033571 lactoferrin transport http://purl.obolibrary.org/obo/GO_0015031 protein transport The directed movement of lactoferrin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0033574 response to testosterone http://purl.obolibrary.org/obo/GO_0033993 response to lipid Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a testosterone stimulus. http://purl.obolibrary.org/obo/GO_0033602 negative regulation of dopamine secretion http://purl.obolibrary.org/obo/GO_0033604 negative regulation of catecholamine secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of dopamine. http://purl.obolibrary.org/obo/GO_0033603 positive regulation of dopamine secretion http://purl.obolibrary.org/obo/GO_0033605 positive regulation of catecholamine secretion Any process that activates or increases the frequency, rate or extent of the regulated release of dopamine. http://purl.obolibrary.org/obo/GO_0033684 regulation of luteinizing hormone secretion http://purl.obolibrary.org/obo/GO_0032276 regulation of gonadotropin secretion Any process that modulates the frequency, rate or extent of the regulated release of luteinizing hormone. http://purl.obolibrary.org/obo/GO_0033685 negative regulation of luteinizing hormone secretion http://purl.obolibrary.org/obo/GO_0033684 regulation of luteinizing hormone secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of luteinizing hormone. http://purl.obolibrary.org/obo/GO_0033686 positive regulation of luteinizing hormone secretion http://purl.obolibrary.org/obo/GO_0033684 regulation of luteinizing hormone secretion Any process that activates or increases the frequency, rate or extent of the regulated release of luteinizing hormone. http://purl.obolibrary.org/obo/GO_0033687 osteoblast proliferation http://purl.obolibrary.org/obo/GO_0008283 cell population proliferation The multiplication or reproduction of osteoblasts, resulting in the expansion of an osteoblast cell population. An osteoblast is a bone-forming cell which secretes an extracellular matrix. Hydroxyapatite crystals are then deposited into the matrix to form bone. http://purl.obolibrary.org/obo/GO_0033688 regulation of osteoblast proliferation http://purl.obolibrary.org/obo/GO_0042127 regulation of cell population proliferation Any process that modulates the frequency, rate or extent of osteoblast proliferation. http://purl.obolibrary.org/obo/GO_0033689 negative regulation of osteoblast proliferation http://purl.obolibrary.org/obo/GO_0008285 negative regulation of cell population proliferation Any process that stops, prevents or reduces the rate or extent of osteoblast proliferation. http://purl.obolibrary.org/obo/GO_0033690 positive regulation of osteoblast proliferation http://purl.obolibrary.org/obo/GO_0033688 regulation of osteoblast proliferation Any process that activates or increases the rate or extent of osteoblast proliferation. http://purl.obolibrary.org/obo/GO_0033696 heterochromatin boundary formation http://purl.obolibrary.org/obo/GO_0070828 heterochromatin organization A process that forms a boundary that limits the spreading of heterochromatin along a chromosome. http://purl.obolibrary.org/obo/GO_0033750 ribosome localization http://purl.obolibrary.org/obo/GO_0051640 organelle localization A process in which a ribosome is transported to, and/or maintained in, a specific location. http://purl.obolibrary.org/obo/GO_0033762 response to glucagon http://purl.obolibrary.org/obo/GO_0043434 response to peptide hormone Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucagon stimulus. http://purl.obolibrary.org/obo/GO_0034067 protein localization to Golgi apparatus http://purl.obolibrary.org/obo/GO_0033365 protein localization to organelle A process in which a protein is transported to, or maintained in, a location within the Golgi apparatus. http://purl.obolibrary.org/obo/GO_0034097 response to cytokine http://purl.obolibrary.org/obo/GO_1901652 response to peptide Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokine stimulus. http://purl.obolibrary.org/obo/GO_0034101 erythrocyte homeostasis http://purl.obolibrary.org/obo/GO_0002262 myeloid cell homeostasis Any process of regulating the production and elimination of erythrocytes within an organism. http://purl.obolibrary.org/obo/GO_0034102 erythrocyte clearance http://purl.obolibrary.org/obo/GO_0048771 tissue remodeling The selective elimination of erythrocytes from the body by autoregulatory mechanisms. http://purl.obolibrary.org/obo/GO_0034103 regulation of tissue remodeling http://purl.obolibrary.org/obo/GO_0051239 regulation of multicellular organismal process Any process that modulates the frequency, rate, or extent of tissue remodeling. http://purl.obolibrary.org/obo/GO_0034104 negative regulation of tissue remodeling http://purl.obolibrary.org/obo/GO_0034103 regulation of tissue remodeling Any process that stops, prevents, or reduces the frequency, rate, or extent of tissue remodeling. http://purl.obolibrary.org/obo/GO_0034105 positive regulation of tissue remodeling http://purl.obolibrary.org/obo/GO_0034103 regulation of tissue remodeling Any process that activates or increases the frequency, rate, or extent of tissue remodeling. http://purl.obolibrary.org/obo/GO_0034106 regulation of erythrocyte clearance http://purl.obolibrary.org/obo/GO_0034103 regulation of tissue remodeling Any process that modulates the frequency, rate, or extent of erythrocyte clearance. http://purl.obolibrary.org/obo/GO_0034107 negative regulation of erythrocyte clearance http://purl.obolibrary.org/obo/GO_0034106 regulation of erythrocyte clearance Any process that stops, prevents, or reduces the frequency, rate, or extent of erythrocyte clearance. http://purl.obolibrary.org/obo/GO_0034108 positive regulation of erythrocyte clearance http://purl.obolibrary.org/obo/GO_0034106 regulation of erythrocyte clearance Any process that activates or increases the frequency, rate, or extent of erythrocyte clearance. http://purl.obolibrary.org/obo/GO_0034242 negative regulation of syncytium formation by plasma membrane fusion http://purl.obolibrary.org/obo/GO_0051129 negative regulation of cellular component organization Any process that decreases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells. http://purl.obolibrary.org/obo/GO_0034307 regulation of ascospore formation http://purl.obolibrary.org/obo/GO_0060284 regulation of cell development Any process that modulates the frequency, rate or extent of ascospore formation. An example of this process is found in Saccharomyces cerevisiae. http://purl.obolibrary.org/obo/GO_0034487 vacuolar amino acid transmembrane transport http://purl.obolibrary.org/obo/GO_0003333 amino acid transmembrane transport The process in which an amino acid is transported from one side of the vacuolar membrane to the other. http://purl.obolibrary.org/obo/GO_0034762 regulation of transmembrane transport http://purl.obolibrary.org/obo/GO_0051049 regulation of transport Any process that modulates the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0034766 negative regulation of monoatomic ion transmembrane transport http://purl.obolibrary.org/obo/GO_0043271 negative regulation of monoatomic ion transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0034767 positive regulation of monoatomic ion transmembrane transport http://purl.obolibrary.org/obo/GO_0043270 positive regulation of monoatomic ion transport Any process that activates or increases the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0035107 appendage morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structures of appendages are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch. http://purl.obolibrary.org/obo/GO_0035108 limb morphogenesis http://purl.obolibrary.org/obo/GO_0035107 appendage morphogenesis The process in which the anatomical structures of a limb are generated and organized. A limb is a paired appendage of a tetrapod used for locomotion or grasping. http://purl.obolibrary.org/obo/GO_0035112 genitalia morphogenesis http://purl.obolibrary.org/obo/GO_0009887 animal organ morphogenesis The process in which the anatomical structures of genitalia are generated and organized. The genitalia are the organs of reproduction or generation, external and internal. http://purl.obolibrary.org/obo/GO_0035270 endocrine system development http://purl.obolibrary.org/obo/GO_0048731 system development Progression of the endocrine system over time, from its formation to a mature structure. The endocrine system is a system of hormones and ductless glands, where the glands release hormones directly into the blood, lymph or other intercellular fluid, and the hormones circulate within the body to affect distant organs. The major glands that make up the human endocrine system are the hypothalamus, pituitary, thyroid, parathryoids, adrenals, pineal body, and the reproductive glands which include the ovaries and testes. http://purl.obolibrary.org/obo/GO_0035869 ciliary transition zone http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure A region of the cilium between the basal body and proximal segment that is characterized by Y-shaped assemblages that connect axonemal microtubules to the ciliary membrane. The ciliary transition zone appears to function as a gate that controls ciliary membrane composition and separates the cytosol from the ciliary plasm. http://purl.obolibrary.org/obo/GO_0036344 platelet morphogenesis http://purl.obolibrary.org/obo/GO_0000902 cell morphogenesis Generation and organization of a platelet, a non-nucleated disk-shaped cell formed by extrusion from megakaryocytes, found in the blood of all mammals, and mainly involved in blood coagulation. http://purl.obolibrary.org/obo/GO_0036477 somatodendritic compartment http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure The region of a neuron that includes the cell body (cell soma) and dendrite(s), but excludes the axon. http://purl.obolibrary.org/obo/GO_0040011 locomotion http://purl.obolibrary.org/obo/GO_0008150 biological_process Self-propelled movement of a cell or organism from one location to another. http://purl.obolibrary.org/obo/GO_0040020 regulation of meiotic nuclear division http://purl.obolibrary.org/obo/GO_0051445 regulation of meiotic cell cycle Any process that modulates the frequency, rate or extent of meiotic nuclear division, the process in which the nucleus of a diploid cell divides twice forming four haploid cells, one or more of which usually function as gametes. http://purl.obolibrary.org/obo/GO_0042102 positive regulation of T cell proliferation http://purl.obolibrary.org/obo/GO_0050870 positive regulation of T cell activation Any process that activates or increases the rate or extent of T cell proliferation. http://purl.obolibrary.org/obo/GO_0042129 regulation of T cell proliferation http://purl.obolibrary.org/obo/GO_0050863 regulation of T cell activation Any process that modulates the frequency, rate or extent of T cell proliferation. http://purl.obolibrary.org/obo/GO_0042130 negative regulation of T cell proliferation http://purl.obolibrary.org/obo/GO_0050868 negative regulation of T cell activation Any process that stops, prevents or reduces the rate or extent of T cell proliferation. http://purl.obolibrary.org/obo/GO_0042246 tissue regeneration http://purl.obolibrary.org/obo/GO_0031099 regeneration The regrowth of lost or destroyed tissues. http://purl.obolibrary.org/obo/GO_0042287 MHC protein binding http://purl.obolibrary.org/obo/GO_0005102 signaling receptor binding Binding to a major histocompatibility complex molecule; a set of molecules displayed on cell surfaces that are responsible for lymphocyte recognition and antigen presentation. http://purl.obolibrary.org/obo/GO_0042306 regulation of protein import into nucleus http://purl.obolibrary.org/obo/GO_1900180 regulation of protein localization to nucleus Any process that modulates the frequency, rate or extent of movement of proteins from the cytoplasm to the nucleus. http://purl.obolibrary.org/obo/GO_0042307 positive regulation of protein import into nucleus http://purl.obolibrary.org/obo/GO_1900182 positive regulation of protein localization to nucleus Any process that activates or increases the frequency, rate or extent of movement of proteins from the cytoplasm into the nucleus. http://purl.obolibrary.org/obo/GO_0042308 negative regulation of protein import into nucleus http://purl.obolibrary.org/obo/GO_1900181 negative regulation of protein localization to nucleus Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of proteins from the cytoplasm into the nucleus. http://purl.obolibrary.org/obo/GO_0042470 melanosome http://purl.obolibrary.org/obo/GO_0048770 pigment granule A tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored. Melanosomes are synthesized in melanocyte cells. http://purl.obolibrary.org/obo/GO_0042552 myelination http://purl.obolibrary.org/obo/GO_0008366 axon ensheathment The process in which myelin sheaths are formed and maintained around neurons. Oligodendrocytes in the brain and spinal cord and Schwann cells in the peripheral nervous system wrap axons with compact layers of their plasma membrane. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier. http://purl.obolibrary.org/obo/GO_0042554 superoxide anion generation http://purl.obolibrary.org/obo/GO_0006801 superoxide metabolic process The enzymatic generation of superoxide, the superoxide anion O2- (superoxide free radical), or any compound containing this species, by a cell in response to environmental stress, thereby mediating the activation of various stress-inducible signaling pathways. http://purl.obolibrary.org/obo/GO_0042611 MHC protein complex http://purl.obolibrary.org/obo/GO_0098797 plasma membrane protein complex A transmembrane protein complex composed of an MHC alpha chain and, in most cases, either an MHC class II beta chain or an invariant beta2-microglobin chain, and with or without a bound peptide, lipid, or polysaccharide antigen. http://purl.obolibrary.org/obo/GO_0042633 hair cycle http://purl.obolibrary.org/obo/GO_0042303 molting cycle The cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair; one of the collection or mass of filaments growing from the skin of an animal, and forming a covering for a part of the head or for any part or the whole of the body. http://purl.obolibrary.org/obo/GO_0042698 ovulation cycle http://purl.obolibrary.org/obo/GO_0048609 multicellular organismal reproductive process The type of sexual cycle seen in females, often with physiologic changes in the endometrium that recur at regular intervals during the reproductive years. http://purl.obolibrary.org/obo/GO_0043022 ribosome binding http://purl.obolibrary.org/obo/GO_0043021 ribonucleoprotein complex binding Binding to a ribosome. http://purl.obolibrary.org/obo/GO_0043025 neuronal cell body http://purl.obolibrary.org/obo/GO_0044297 cell body The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites. http://purl.obolibrary.org/obo/GO_0043062 extracellular structure organization http://purl.obolibrary.org/obo/GO_0016043 cellular component organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures in the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane, and also covers the host cell environment outside an intracellular parasite. http://purl.obolibrary.org/obo/GO_0043069 negative regulation of programmed cell death http://purl.obolibrary.org/obo/GO_0043067 regulation of programmed cell death Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes. http://purl.obolibrary.org/obo/GO_0043177 organic acid binding http://purl.obolibrary.org/obo/GO_0036094 small molecule binding Binding to an organic acid, any acidic compound containing carbon in covalent linkage. http://purl.obolibrary.org/obo/GO_0043227 membrane-bounded organelle http://purl.obolibrary.org/obo/GO_0043226 organelle Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane. http://purl.obolibrary.org/obo/GO_0043233 organelle lumen http://purl.obolibrary.org/obo/GO_0031974 membrane-enclosed lumen The internal volume enclosed by the membranes of a particular organelle; includes the volume enclosed by a single organelle membrane, e.g. endoplasmic reticulum lumen, or the volume enclosed by the innermost of the two lipid bilayers of an organelle envelope, e.g. nuclear lumen. http://purl.obolibrary.org/obo/GO_0043253 chloroplast ribosome http://purl.obolibrary.org/obo/GO_0009547 plastid ribosome A ribosome contained within a chloroplast. http://purl.obolibrary.org/obo/GO_0043297 apical junction assembly http://purl.obolibrary.org/obo/GO_0007043 cell-cell junction assembly The formation of an apical junction, a functional unit located near the cell apex at the points of contact between epithelial cells composed of the tight junction, the zonula adherens junction and the desmosomes, by the aggregation, arrangement and bonding together of its constituents. http://purl.obolibrary.org/obo/GO_0043370 regulation of CD4-positive, alpha-beta T cell differentiation http://purl.obolibrary.org/obo/GO_2000514 regulation of CD4-positive, alpha-beta T cell activation Any process that modulates the frequency, rate, or extent of CD4-positive, alpha-beta T cell differentiation. http://purl.obolibrary.org/obo/GO_0043371 negative regulation of CD4-positive, alpha-beta T cell differentiation http://purl.obolibrary.org/obo/GO_2000515 negative regulation of CD4-positive, alpha-beta T cell activation Any process that stops, prevents, or reduces the frequency, rate, or extent of CD4-positive, alpha-beta T cell differentiation. http://purl.obolibrary.org/obo/GO_0043372 positive regulation of CD4-positive, alpha-beta T cell differentiation http://purl.obolibrary.org/obo/GO_2000516 positive regulation of CD4-positive, alpha-beta T cell activation Any process that activates or increases the frequency, rate or extent of CD4-positive, alpha-beta T cell differentiation. http://purl.obolibrary.org/obo/GO_0043393 regulation of protein binding http://purl.obolibrary.org/obo/GO_0051098 regulation of binding Any process that modulates the frequency, rate or extent of protein binding. http://purl.obolibrary.org/obo/GO_0043434 response to peptide hormone http://purl.obolibrary.org/obo/GO_1901698 response to nitrogen compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide hormone stimulus. A peptide hormone is any of a class of peptides that are secreted into the blood stream and have endocrine functions in living animals. http://purl.obolibrary.org/obo/GO_0043473 pigmentation http://purl.obolibrary.org/obo/GO_0008150 biological_process The accumulation of pigment in an organism, tissue or cell, either by increased deposition or by increased number of cells. http://purl.obolibrary.org/obo/GO_0043555 regulation of translation in response to stress http://purl.obolibrary.org/obo/GO_0006417 regulation of translation Modulation of the frequency, rate or extent of translation as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). http://purl.obolibrary.org/obo/GO_0043556 regulation of translation in response to oxidative stress http://purl.obolibrary.org/obo/GO_0032055 negative regulation of translation in response to stress Any process that modulates the frequency, rate or extent of translation as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals. http://purl.obolibrary.org/obo/GO_0043584 nose development http://purl.obolibrary.org/obo/GO_0007423 sensory organ development The process whose specific outcome is the progression of the nose over time, from its formation to the mature structure. The nose is the specialized structure of the face that serves as the organ of the sense of smell and as part of the respiratory system. Includes the nasi externus (external nose) and cavitas nasi (nasal cavity). http://purl.obolibrary.org/obo/GO_0043588 skin development http://purl.obolibrary.org/obo/GO_0048513 animal organ development The process whose specific outcome is the progression of the skin over time, from its formation to the mature structure. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner vascular dermis (cutis, corium or true skin) composed mostly of connective tissue. http://purl.obolibrary.org/obo/GO_0043615 astrocyte cell migration http://purl.obolibrary.org/obo/GO_0008347 glial cell migration The orderly movement of an astrocyte, a class of large neuroglial (macroglial) cells in the central nervous system, the largest and most numerous neuroglial cells in the brain and spinal cord. http://purl.obolibrary.org/obo/GO_0043934 sporulation http://purl.obolibrary.org/obo/GO_0032502 developmental process The process whose specific outcome is the progression of a spore over time, from its initiation to the mature structure. A spore is a structure that can be used for dissemination, for survival of adverse conditions because of its heat and desiccation resistance, and/or for reproduction. http://purl.obolibrary.org/obo/GO_0043935 sexual sporulation resulting in formation of a cellular spore http://purl.obolibrary.org/obo/GO_0034293 sexual sporulation The formation of spores derived from the products of meiosis. A cellular spore is a cell form that can be used for dissemination, for survival of adverse conditions because of its heat and desiccation resistance, and/or for reproduction. http://purl.obolibrary.org/obo/GO_0044057 regulation of system process http://purl.obolibrary.org/obo/GO_0051239 regulation of multicellular organismal process Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by any of the organs or tissues in an organ system. http://purl.obolibrary.org/obo/GO_0044088 regulation of vacuole organization http://purl.obolibrary.org/obo/GO_0033043 regulation of organelle organization Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a vacuole. http://purl.obolibrary.org/obo/GO_0044092 negative regulation of molecular function http://purl.obolibrary.org/obo/GO_0065009 regulation of molecular function Any process that stops or reduces the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding. http://purl.obolibrary.org/obo/GO_0044093 positive regulation of molecular function http://purl.obolibrary.org/obo/GO_0065009 regulation of molecular function Any process that activates or increases the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding. http://purl.obolibrary.org/obo/GO_0044423 virion component http://purl.obolibrary.org/obo/GO_0005575 cellular_component Any constituent part of a virion, a complete fully infectious extracellular virus particle. http://purl.obolibrary.org/obo/GO_0044782 cilium organization http://purl.obolibrary.org/obo/GO_0006996 organelle organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole. http://purl.obolibrary.org/obo/GO_0044877 protein-containing complex binding http://purl.obolibrary.org/obo/GO_0005488 binding Binding to a macromolecular complex. http://purl.obolibrary.org/obo/GO_0045009 chitosome http://purl.obolibrary.org/obo/GO_0031410 cytoplasmic vesicle An intracellular membrane-bounded particle found in fungi and containing chitin synthase; it synthesizes chitin microfibrils. Chitin synthase activity exists in chitosomes and they are proposed to act as a reservoir for regulated transport of chitin synthase enzymes to the division septum. http://purl.obolibrary.org/obo/GO_0045110 intermediate filament bundle assembly http://purl.obolibrary.org/obo/GO_0045109 intermediate filament organization The formation of the bundles of intermediate filaments. Intermediate filament-associated proteins (IFAPs) cross-link intermediate filaments with one another, forming a bundle or a network, and with other cell structures, including the plasma membrane. The organization of intermediate filaments and their supportive function in various cells types depends in large part on their linkage to other cell structures via IFAPs. http://purl.obolibrary.org/obo/GO_0045168 cell-cell signaling involved in cell fate commitment http://purl.obolibrary.org/obo/GO_0007267 cell-cell signaling Signaling at long or short range between cells that results in the commitment of a cell to a certain fate. http://purl.obolibrary.org/obo/GO_0045185 maintenance of protein location http://purl.obolibrary.org/obo/GO_0051235 maintenance of location Any process in which a protein is maintained in a location and prevented from moving elsewhere. These include sequestration, stabilization to prevent transport elsewhere and the active retrieval of proteins that do move away. http://purl.obolibrary.org/obo/GO_0045202 synapse http://purl.obolibrary.org/obo/GO_0030054 cell junction The junction between an axon of one neuron and a dendrite of another neuron, a muscle fiber or a glial cell. As the axon approaches the synapse it enlarges into a specialized structure, the presynaptic terminal bouton, which contains mitochondria and synaptic vesicles. At the tip of the terminal bouton is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic terminal bouton secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane. http://purl.obolibrary.org/obo/GO_0045580 regulation of T cell differentiation http://purl.obolibrary.org/obo/GO_0050863 regulation of T cell activation Any process that modulates the frequency, rate or extent of T cell differentiation. http://purl.obolibrary.org/obo/GO_0045581 negative regulation of T cell differentiation http://purl.obolibrary.org/obo/GO_0050868 negative regulation of T cell activation Any process that stops, prevents, or reduces the frequency, rate or extent of T cell differentiation. http://purl.obolibrary.org/obo/GO_0045582 positive regulation of T cell differentiation http://purl.obolibrary.org/obo/GO_0050870 positive regulation of T cell activation Any process that activates or increases the frequency, rate or extent of T cell differentiation. http://purl.obolibrary.org/obo/GO_0045589 regulation of regulatory T cell differentiation http://purl.obolibrary.org/obo/GO_0045580 regulation of T cell differentiation Any process that modulates the frequency, rate or extent of differentiation of regulatory T cells. http://purl.obolibrary.org/obo/GO_0045590 negative regulation of regulatory T cell differentiation http://purl.obolibrary.org/obo/GO_0045589 regulation of regulatory T cell differentiation Any process that stops, prevents, or reduces the rate of differentiation of regulatory T cells. http://purl.obolibrary.org/obo/GO_0045591 positive regulation of regulatory T cell differentiation http://purl.obolibrary.org/obo/GO_0045589 regulation of regulatory T cell differentiation Any process that activates or increases the frequency, rate or extent of differentiation of regulatory T cells. http://purl.obolibrary.org/obo/GO_0045619 regulation of lymphocyte differentiation http://purl.obolibrary.org/obo/GO_0051249 regulation of lymphocyte activation Any process that modulates the frequency, rate or extent of lymphocyte differentiation. http://purl.obolibrary.org/obo/GO_0045620 negative regulation of lymphocyte differentiation http://purl.obolibrary.org/obo/GO_0051250 negative regulation of lymphocyte activation Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte differentiation. http://purl.obolibrary.org/obo/GO_0045621 positive regulation of lymphocyte differentiation http://purl.obolibrary.org/obo/GO_0051251 positive regulation of lymphocyte activation Any process that activates or increases the frequency, rate or extent of lymphocyte differentiation. http://purl.obolibrary.org/obo/GO_0045717 negative regulation of fatty acid biosynthetic process http://purl.obolibrary.org/obo/GO_0051055 negative regulation of lipid biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids. http://purl.obolibrary.org/obo/GO_0045763 negative regulation of amino acid metabolic process http://purl.obolibrary.org/obo/GO_0009892 negative regulation of metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amino acid. http://purl.obolibrary.org/obo/GO_0045764 positive regulation of amino acid metabolic process http://purl.obolibrary.org/obo/GO_0009893 positive regulation of metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amino acid. http://purl.obolibrary.org/obo/GO_0045778 positive regulation of ossification http://purl.obolibrary.org/obo/GO_0030278 regulation of ossification Any process that activates or increases the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance. http://purl.obolibrary.org/obo/GO_0045835 negative regulation of meiotic nuclear division http://purl.obolibrary.org/obo/GO_0010948 negative regulation of cell cycle process Any process that stops, prevents, or reduces the frequency, rate or extent of meiosis. http://purl.obolibrary.org/obo/GO_0045836 positive regulation of meiotic nuclear division http://purl.obolibrary.org/obo/GO_0090068 positive regulation of cell cycle process Any process that activates or increases the frequency, rate or extent of meiosis. http://purl.obolibrary.org/obo/GO_0045840 positive regulation of mitotic nuclear division http://purl.obolibrary.org/obo/GO_0090068 positive regulation of cell cycle process Any process that activates or increases the frequency, rate or extent of mitosis. http://purl.obolibrary.org/obo/GO_0045926 negative regulation of growth http://purl.obolibrary.org/obo/GO_0048519 negative regulation of biological process Any process that stops, prevents or reduces the rate or extent of growth, the increase in size or mass of all or part of an organism. http://purl.obolibrary.org/obo/GO_0045927 positive regulation of growth http://purl.obolibrary.org/obo/GO_0048518 positive regulation of biological process Any process that activates or increases the rate or extent of growth, the increase in size or mass of all or part of an organism. http://purl.obolibrary.org/obo/GO_0045947 negative regulation of translational initiation http://purl.obolibrary.org/obo/GO_0017148 negative regulation of translation Any process that stops, prevents, or reduces the frequency, rate or extent of translational initiation. http://purl.obolibrary.org/obo/GO_0045948 positive regulation of translational initiation http://purl.obolibrary.org/obo/GO_0045727 positive regulation of translation Any process that activates or increases the frequency, rate or extent of translational initiation. http://purl.obolibrary.org/obo/GO_0045980 negative regulation of nucleotide metabolic process http://purl.obolibrary.org/obo/GO_0045936 negative regulation of phosphate metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleotides. http://purl.obolibrary.org/obo/GO_0045981 positive regulation of nucleotide metabolic process http://purl.obolibrary.org/obo/GO_0045937 positive regulation of phosphate metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleotides. http://purl.obolibrary.org/obo/GO_0046364 monosaccharide biosynthetic process http://purl.obolibrary.org/obo/GO_0044283 small molecule biosynthetic process The chemical reactions and pathways resulting in the formation of monosaccharides, polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. http://purl.obolibrary.org/obo/GO_0046459 short-chain fatty acid metabolic process http://purl.obolibrary.org/obo/GO_0006631 fatty acid metabolic process The chemical reactions and pathways involving a short-chain fatty acid. A short-chain fatty acid has an aliphatic tail containing fewer than 6 carbons. http://purl.obolibrary.org/obo/GO_0046660 female sex differentiation http://purl.obolibrary.org/obo/GO_0007548 sex differentiation The establishment of the sex of a female organism by physical differentiation. http://purl.obolibrary.org/obo/GO_0046683 response to organophosphorus http://purl.obolibrary.org/obo/GO_0042221 response to chemical Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organophosphorus stimulus. Organophosphorus is a compound containing phosphorus bound to an organic molecule; several organophosphorus compounds are used as insecticides, and they are highly toxic cholinesterase inhibitors. http://purl.obolibrary.org/obo/GO_0046887 positive regulation of hormone secretion http://purl.obolibrary.org/obo/GO_0010647 positive regulation of cell communication Any process that activates or increases the frequency, rate or extent of the regulated release of a hormone from a cell. http://purl.obolibrary.org/obo/GO_0046888 negative regulation of hormone secretion http://purl.obolibrary.org/obo/GO_0010648 negative regulation of cell communication Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a hormone from a cell. http://purl.obolibrary.org/obo/GO_0047497 mitochondrion transport along microtubule http://purl.obolibrary.org/obo/GO_0034643 establishment of mitochondrion localization, microtubule-mediated The directed movement of a mitochondrion along a microtubule, mediated by motor proteins. http://purl.obolibrary.org/obo/GO_0048020 CCR chemokine receptor binding http://purl.obolibrary.org/obo/GO_0042379 chemokine receptor binding Binding to a CCR chemokine receptor. http://purl.obolibrary.org/obo/GO_0048483 autonomic nervous system development http://purl.obolibrary.org/obo/GO_0048731 system development The process whose specific outcome is the progression of the autonomic nervous system over time, from its formation to the mature structure. The autonomic nervous system is composed of neurons that are not under conscious control, and is comprised of two antagonistic components, the sympathetic and parasympathetic nervous systems. The autonomic nervous system regulates key functions including the activity of the cardiac (heart) muscle, smooth muscles (e.g. of the gut), and glands. http://purl.obolibrary.org/obo/GO_0048486 parasympathetic nervous system development http://purl.obolibrary.org/obo/GO_0048731 system development The process whose specific outcome is the progression of the parasympathetic nervous system over time, from its formation to the mature structure. The parasympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system. Parasympathetic nerves emerge cranially as pre ganglionic fibers from oculomotor, facial, glossopharyngeal and vagus and from the sacral region of the spinal cord. Most neurons are cholinergic and responses are mediated by muscarinic receptors. The parasympathetic system innervates, for example: salivary glands, thoracic and abdominal viscera, bladder and genitalia. http://purl.obolibrary.org/obo/GO_0048521 negative regulation of behavior http://purl.obolibrary.org/obo/GO_0050795 regulation of behavior Any process that stops, prevents, or reduces the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli. http://purl.obolibrary.org/obo/GO_0048534 hematopoietic or lymphoid organ development http://purl.obolibrary.org/obo/GO_0048513 animal organ development The process whose specific outcome is the progression of any organ involved in hematopoiesis (also known as hemopoiesis) or lymphoid cell activation over time, from its formation to the mature structure. Such development includes differentiation of resident cell types (stromal cells) and of migratory cell types dependent on the unique microenvironment afforded by the organ for their proper differentiation. http://purl.obolibrary.org/obo/GO_0048545 response to steroid hormone http://purl.obolibrary.org/obo/GO_0033993 response to lipid Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a steroid hormone stimulus. http://purl.obolibrary.org/obo/GO_0048640 negative regulation of developmental growth http://purl.obolibrary.org/obo/GO_0048638 regulation of developmental growth Any process that stops, prevents, or reduces the frequency, rate or extent of developmental growth. http://purl.obolibrary.org/obo/GO_0048730 epidermis morphogenesis http://purl.obolibrary.org/obo/GO_0002009 morphogenesis of an epithelium The process in which the anatomical structures of the epidermis are generated and organized. The epidermis is the outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species. http://purl.obolibrary.org/obo/GO_0048736 appendage development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of an appendage over time, from its formation to the mature structure. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch. http://purl.obolibrary.org/obo/GO_0048857 neural nucleus development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The biological process whose specific outcome is the progression of a neural nucleus from its initial condition to its mature state. A neural nucleus is an anatomical structure consisting of a discrete aggregate of neuronal soma. http://purl.obolibrary.org/obo/GO_0048860 glioblast division http://purl.obolibrary.org/obo/GO_0051301 cell division The process resulting in the physical partitioning and separation of a glioblast into daughter cells. http://purl.obolibrary.org/obo/GO_0048909 anterior lateral line nerve development http://purl.obolibrary.org/obo/GO_0048892 lateral line nerve development The process whose specific outcome is the progression of the anterior lateral line nerve over time, form its formation to the mature structure. The anterior lateral line nerve contains efferent axons that innervate hair cells of the ALL and afferent axons that project to an octavolateralis column in the hindbrain. The octavolateralis column consists of the medial octavolateralis nucleus (MON), the caudal octavolateralis nucleus, and the magnocellular nucleus. http://purl.obolibrary.org/obo/GO_0048918 posterior lateral line nerve development http://purl.obolibrary.org/obo/GO_0048892 lateral line nerve development The process whose specific outcome is the progression of the posterior lateral line nerve over time, from its formation to the mature structure. The posterior lateral line nerve innervates hair cells of the PLL and projects to an octavolateralis column in the hindbrain that consists of the medial octavolateralis nucleus (MON), the caudal octavolateralis nucleus, and the magnocellular nucleus. http://purl.obolibrary.org/obo/GO_0050670 regulation of lymphocyte proliferation http://purl.obolibrary.org/obo/GO_0051249 regulation of lymphocyte activation Any process that modulates the frequency, rate or extent of lymphocyte proliferation. http://purl.obolibrary.org/obo/GO_0050671 positive regulation of lymphocyte proliferation http://purl.obolibrary.org/obo/GO_0051251 positive regulation of lymphocyte activation Any process that activates or increases the rate or extent of lymphocyte proliferation. http://purl.obolibrary.org/obo/GO_0050672 negative regulation of lymphocyte proliferation http://purl.obolibrary.org/obo/GO_0051250 negative regulation of lymphocyte activation Any process that stops, prevents or reduces the rate or extent of lymphocyte proliferation. http://purl.obolibrary.org/obo/GO_0050714 positive regulation of protein secretion http://purl.obolibrary.org/obo/GO_0051222 positive regulation of protein transport Any process that activates or increases the frequency, rate or extent of the controlled release of a protein from a cell. http://purl.obolibrary.org/obo/GO_0050770 regulation of axonogenesis http://purl.obolibrary.org/obo/GO_0010975 regulation of neuron projection development Any process that modulates the frequency, rate or extent of axonogenesis, the generation of an axon, the long process of a neuron. http://purl.obolibrary.org/obo/GO_0050771 negative regulation of axonogenesis http://purl.obolibrary.org/obo/GO_0010977 negative regulation of neuron projection development Any process that stops, prevents, or reduces the frequency, rate or extent of axonogenesis. http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process Any process that modulates the frequency, rate or extent of development, the biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). http://purl.obolibrary.org/obo/GO_0050795 regulation of behavior http://purl.obolibrary.org/obo/GO_0051239 regulation of multicellular organismal process Any process that modulates the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli. http://purl.obolibrary.org/obo/GO_0050796 regulation of insulin secretion http://purl.obolibrary.org/obo/GO_0090276 regulation of peptide hormone secretion Any process that modulates the frequency, rate or extent of the regulated release of insulin. http://purl.obolibrary.org/obo/GO_0050804 modulation of chemical synaptic transmission http://purl.obolibrary.org/obo/GO_0099177 regulation of trans-synaptic signaling Any process that modulates the frequency or amplitude of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse. Amplitude, in this case, refers to the change in postsynaptic membrane potential due to a single instance of synaptic transmission. http://purl.obolibrary.org/obo/GO_0050805 negative regulation of synaptic transmission http://purl.obolibrary.org/obo/GO_0010648 negative regulation of cell communication Any process that stops, prevents, or reduces the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse. http://purl.obolibrary.org/obo/GO_0050818 regulation of coagulation http://purl.obolibrary.org/obo/GO_0051239 regulation of multicellular organismal process Any process that modulates the frequency, rate or extent of coagulation, the process in which a fluid solution, or part of it, changes into a solid or semisolid mass. http://purl.obolibrary.org/obo/GO_0050819 negative regulation of coagulation http://purl.obolibrary.org/obo/GO_0050818 regulation of coagulation Any process that stops, prevents, or reduces the frequency, rate or extent of coagulation. http://purl.obolibrary.org/obo/GO_0050820 positive regulation of coagulation http://purl.obolibrary.org/obo/GO_0050818 regulation of coagulation Any process that activates or increases the frequency, rate or extent of coagulation. http://purl.obolibrary.org/obo/GO_0050849 negative regulation of calcium-mediated signaling http://purl.obolibrary.org/obo/GO_1902532 negative regulation of intracellular signal transduction Any process that stops, prevents, or reduces the frequency, rate or extent of calcium-mediated signaling. http://purl.obolibrary.org/obo/GO_0050850 positive regulation of calcium-mediated signaling http://purl.obolibrary.org/obo/GO_1902533 positive regulation of intracellular signal transduction Any process that activates or increases the frequency, rate or extent of calcium-mediated signaling. http://purl.obolibrary.org/obo/GO_0050864 regulation of B cell activation http://purl.obolibrary.org/obo/GO_0051249 regulation of lymphocyte activation Any process that modulates the frequency, rate or extent of B cell activation. http://purl.obolibrary.org/obo/GO_0050869 negative regulation of B cell activation http://purl.obolibrary.org/obo/GO_0051250 negative regulation of lymphocyte activation Any process that stops, prevents, or reduces the frequency, rate or extent of B cell activation. http://purl.obolibrary.org/obo/GO_0050870 positive regulation of T cell activation http://purl.obolibrary.org/obo/GO_0050863 regulation of T cell activation Any process that activates or increases the frequency, rate or extent of T cell activation. http://purl.obolibrary.org/obo/GO_0050871 positive regulation of B cell activation http://purl.obolibrary.org/obo/GO_0051251 positive regulation of lymphocyte activation Any process that activates or increases the frequency, rate or extent of B cell activation. http://purl.obolibrary.org/obo/GO_0050884 neuromuscular process controlling posture http://purl.obolibrary.org/obo/GO_0050905 neuromuscular process Any process in which an organism voluntarily modulates its posture, the alignment of its anatomical parts. http://purl.obolibrary.org/obo/GO_0050931 pigment cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a pigmented cell, such as a melanocyte. http://purl.obolibrary.org/obo/GO_0051017 actin filament bundle assembly http://purl.obolibrary.org/obo/GO_0022607 cellular component assembly The assembly of actin filament bundles; actin filaments are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness. http://purl.obolibrary.org/obo/GO_0051054 positive regulation of DNA metabolic process http://purl.obolibrary.org/obo/GO_0051052 regulation of DNA metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving DNA. http://purl.obolibrary.org/obo/GO_0051099 positive regulation of binding http://purl.obolibrary.org/obo/GO_0051098 regulation of binding Any process that activates or increases the rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule. http://purl.obolibrary.org/obo/GO_0051100 negative regulation of binding http://purl.obolibrary.org/obo/GO_0051098 regulation of binding Any process that stops or reduces the rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule. http://purl.obolibrary.org/obo/GO_0051179 localization http://purl.obolibrary.org/obo/GO_0008150 biological_process Any process in which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported, tethered to or otherwise maintained in a specific location. In the case of substances, localization may also be achieved via selective degradation. http://purl.obolibrary.org/obo/GO_0051223 regulation of protein transport http://purl.obolibrary.org/obo/GO_0051049 regulation of transport Any process that modulates the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0051235 maintenance of location http://purl.obolibrary.org/obo/GO_0051179 localization Any process in which a cell, substance or cellular entity, such as a protein complex or organelle, is maintained in a location and prevented from moving elsewhere. http://purl.obolibrary.org/obo/GO_0051246 regulation of protein metabolic process http://purl.obolibrary.org/obo/GO_0060255 regulation of macromolecule metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein. http://purl.obolibrary.org/obo/GO_0051247 positive regulation of protein metabolic process http://purl.obolibrary.org/obo/GO_0051246 regulation of protein metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein. http://purl.obolibrary.org/obo/GO_0051248 negative regulation of protein metabolic process http://purl.obolibrary.org/obo/GO_0051246 regulation of protein metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of chemical reactions and pathways involving a protein. http://purl.obolibrary.org/obo/GO_0051249 regulation of lymphocyte activation http://purl.obolibrary.org/obo/GO_0002694 regulation of leukocyte activation Any process that modulates the frequency, rate or extent of lymphocyte activation. http://purl.obolibrary.org/obo/GO_0051250 negative regulation of lymphocyte activation http://purl.obolibrary.org/obo/GO_0051249 regulation of lymphocyte activation Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte activation. http://purl.obolibrary.org/obo/GO_0051251 positive regulation of lymphocyte activation http://purl.obolibrary.org/obo/GO_0051249 regulation of lymphocyte activation Any process that activates or increases the frequency, rate or extent of lymphocyte activation. http://purl.obolibrary.org/obo/GO_0051253 negative regulation of RNA metabolic process http://purl.obolibrary.org/obo/GO_0045934 negative regulation of nucleobase-containing compound metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving RNA. http://purl.obolibrary.org/obo/GO_0051280 negative regulation of release of sequestered calcium ion into cytosol http://purl.obolibrary.org/obo/GO_0051279 regulation of release of sequestered calcium ion into cytosol Any process that stops, prevents, or reduces the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria. http://purl.obolibrary.org/obo/GO_0051281 positive regulation of release of sequestered calcium ion into cytosol http://purl.obolibrary.org/obo/GO_0051279 regulation of release of sequestered calcium ion into cytosol Any process that activates or increases the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria. http://purl.obolibrary.org/obo/GO_0051418 microtubule nucleation by microtubule organizing center http://purl.obolibrary.org/obo/GO_0007020 microtubule nucleation The 'de novo' formation of a microtubule, mediated by the microtubule organizing center. http://purl.obolibrary.org/obo/GO_0051644 plastid localization http://purl.obolibrary.org/obo/GO_0051640 organelle localization Any process in which a plastid is transported to, and/or maintained in, a specific location within the cell. http://purl.obolibrary.org/obo/GO_0051647 nucleus localization http://purl.obolibrary.org/obo/GO_0051640 organelle localization Any process in which the nucleus is transported to, and/or maintained in, a specific location within the cell. http://purl.obolibrary.org/obo/GO_0051648 vesicle localization http://purl.obolibrary.org/obo/GO_0051640 organelle localization Any process in which a vesicle or vesicles are transported to, and/or maintained in, a specific location. http://purl.obolibrary.org/obo/GO_0051655 maintenance of vesicle location http://purl.obolibrary.org/obo/GO_0051648 vesicle localization Any process in which a vesicle is maintained in a specific location within a cell and prevented from moving elsewhere. http://purl.obolibrary.org/obo/GO_0051656 establishment of organelle localization http://purl.obolibrary.org/obo/GO_0051640 organelle localization The directed movement of an organelle to a specific location. http://purl.obolibrary.org/obo/GO_0051668 localization within membrane http://purl.obolibrary.org/obo/GO_0051641 cellular localization Any process in which a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a membrane. http://purl.obolibrary.org/obo/GO_0051674 localization of cell http://purl.obolibrary.org/obo/GO_0051179 localization Any process in which a cell is transported to, and/or maintained in, a specific location. http://purl.obolibrary.org/obo/GO_0051781 positive regulation of cell division http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the frequency, rate or extent of cell division. http://purl.obolibrary.org/obo/GO_0051782 negative regulation of cell division http://purl.obolibrary.org/obo/GO_0051302 regulation of cell division Any process that stops, prevents, or reduces the frequency, rate or extent of cell division. http://purl.obolibrary.org/obo/GO_0051790 short-chain fatty acid biosynthetic process http://purl.obolibrary.org/obo/GO_0046459 short-chain fatty acid metabolic process The chemical reactions and pathways resulting in the formation of a short-chain fatty acid. A short-chain fatty acid has an aliphatic tail containing fewer than 6 carbons. http://purl.obolibrary.org/obo/GO_0051861 glycolipid binding http://purl.obolibrary.org/obo/GO_0097367 carbohydrate derivative binding Binding to a glycolipid, any compound containing one or more monosaccharide residues bound by a glycosidic linkage to a hydrophobic group such as an acylglycerol, a sphingoid, a ceramide (N-acylsphingoid) or a prenyl phosphate. http://purl.obolibrary.org/obo/GO_0051875 pigment granule localization http://purl.obolibrary.org/obo/GO_0051648 vesicle localization Any process in which a pigment granule is transported to, and/or maintained in, a specific location within the cell. http://purl.obolibrary.org/obo/GO_0051904 pigment granule transport http://purl.obolibrary.org/obo/GO_0051905 establishment of pigment granule localization The directed movement of pigment granules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0051905 establishment of pigment granule localization http://purl.obolibrary.org/obo/GO_0051650 establishment of vesicle localization The directed movement of a pigment granule to a specific location. http://purl.obolibrary.org/obo/GO_0051932 synaptic transmission, GABAergic http://purl.obolibrary.org/obo/GO_0007268 chemical synaptic transmission The vesicular release of gamma-aminobutyric acid (GABA). from a presynapse, across a chemical synapse, the subsequent activation of GABA receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse. http://purl.obolibrary.org/obo/GO_0051960 regulation of nervous system development http://purl.obolibrary.org/obo/GO_2000026 regulation of multicellular organismal development Any process that modulates the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue. http://purl.obolibrary.org/obo/GO_0051961 negative regulation of nervous system development http://purl.obolibrary.org/obo/GO_0051960 regulation of nervous system development Any process that stops, prevents, or reduces the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue. http://purl.obolibrary.org/obo/GO_0051962 positive regulation of nervous system development http://purl.obolibrary.org/obo/GO_0051960 regulation of nervous system development Any process that activates, maintains or increases the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue. http://purl.obolibrary.org/obo/GO_0051983 regulation of chromosome segregation http://purl.obolibrary.org/obo/GO_0010564 regulation of cell cycle process Any process that modulates the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets. http://purl.obolibrary.org/obo/GO_0051985 negative regulation of chromosome segregation http://purl.obolibrary.org/obo/GO_0010948 negative regulation of cell cycle process Any process that stops, prevents, or reduces the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets. http://purl.obolibrary.org/obo/GO_0055001 muscle cell development http://purl.obolibrary.org/obo/GO_0048468 cell development The process whose specific outcome is the progression of a muscle cell over time, from its formation to the mature structure. Muscle cell development does not include the steps involved in committing an unspecified cell to the muscle cell fate. http://purl.obolibrary.org/obo/GO_0055057 neuroblast division http://purl.obolibrary.org/obo/GO_0051301 cell division The process resulting in the physical partitioning and separation of a neuroblast into daughter cells. A neuroblast is any cell that will divide and give rise to a neuron. http://purl.obolibrary.org/obo/GO_0055062 phosphate ion homeostasis http://purl.obolibrary.org/obo/GO_0098771 inorganic ion homeostasis Any process involved in the maintenance of an internal steady state of phosphate ions within an organism or cell. http://purl.obolibrary.org/obo/GO_0055075 potassium ion homeostasis http://purl.obolibrary.org/obo/GO_0098771 inorganic ion homeostasis Any process involved in the maintenance of an internal steady state of potassium ions within an organism or cell. http://purl.obolibrary.org/obo/GO_0055080 monoatomic cation homeostasis http://purl.obolibrary.org/obo/GO_0050801 monoatomic ion homeostasis Any process involved in the maintenance of an internal steady state of monoatomic cations within an organism or cell. Monatomic cations (also called simple cations) are cations consisting of exactly one atom. http://purl.obolibrary.org/obo/GO_0055123 digestive system development http://purl.obolibrary.org/obo/GO_0048731 system development The process whose specific outcome is the progression of the digestive system over time, from its formation to the mature structure. The digestive system is the entire structure in which digestion takes place. Digestion is all of the physical, chemical, and biochemical processes carried out by multicellular organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism. http://purl.obolibrary.org/obo/GO_0060019 radial glial cell differentiation http://purl.obolibrary.org/obo/GO_0010001 glial cell differentiation The process in which neuroepithelial cells of the neural tube give rise to radial glial cells, specialized bipotential progenitors cells of the brain. Differentiation includes the processes involved in commitment of a cell to a specific fate. http://purl.obolibrary.org/obo/GO_0060090 molecular adaptor activity http://purl.obolibrary.org/obo/GO_0003674 molecular_function The binding activity of a molecule that brings together two or more molecules through a selective, non-covalent, often stoichiometric interaction, permitting those molecules to function in a coordinated way. http://purl.obolibrary.org/obo/GO_0060142 regulation of syncytium formation by plasma membrane fusion http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells. http://purl.obolibrary.org/obo/GO_0060143 positive regulation of syncytium formation by plasma membrane fusion http://purl.obolibrary.org/obo/GO_0051130 positive regulation of cellular component organization Any process that increases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells. http://purl.obolibrary.org/obo/GO_0060170 ciliary membrane http://purl.obolibrary.org/obo/GO_0031253 cell projection membrane The portion of the plasma membrane surrounding a cilium. http://purl.obolibrary.org/obo/GO_0060896 neural plate pattern specification http://purl.obolibrary.org/obo/GO_0007389 pattern specification process The developmental process that results in the creation of defined areas or spaces within the neural plate to which cells respond and eventually are instructed to differentiate. http://purl.obolibrary.org/obo/GO_0060897 neural plate regionalization http://purl.obolibrary.org/obo/GO_0060896 neural plate pattern specification The pattern specification process that results in the subdivision of an axis or axes of the neural plate in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment. http://purl.obolibrary.org/obo/GO_0060986 endocrine hormone secretion http://purl.obolibrary.org/obo/GO_0046879 hormone secretion The regulated release of a hormone into the circulatory system. http://purl.obolibrary.org/obo/GO_0061036 positive regulation of cartilage development http://purl.obolibrary.org/obo/GO_0061035 regulation of cartilage development Any process that increases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate. http://purl.obolibrary.org/obo/GO_0061037 negative regulation of cartilage development http://purl.obolibrary.org/obo/GO_0061035 regulation of cartilage development Any process that decreases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate. http://purl.obolibrary.org/obo/GO_0061041 regulation of wound healing http://purl.obolibrary.org/obo/GO_1903034 regulation of response to wounding Any process that modulates the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury. http://purl.obolibrary.org/obo/GO_0061045 negative regulation of wound healing http://purl.obolibrary.org/obo/GO_0032102 negative regulation of response to external stimulus Any process that decreases the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury. http://purl.obolibrary.org/obo/GO_0061180 mammary gland epithelium development http://purl.obolibrary.org/obo/GO_0060429 epithelium development The process whose specific outcome is the progression of the mammary gland epithelium over time, from its formation to the mature structure. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk. http://purl.obolibrary.org/obo/GO_0061458 reproductive system development http://purl.obolibrary.org/obo/GO_0048731 system development The progression of the reproductive system over time from its formation to the mature structure. The reproductive system consists of the organs that function in reproduction. http://purl.obolibrary.org/obo/GO_0065010 extracellular membrane-bounded organelle http://purl.obolibrary.org/obo/GO_0043230 extracellular organelle Organized structure of distinctive morphology and function, bounded by a lipid bilayer membrane and occurring outside the cell. http://purl.obolibrary.org/obo/GO_0070167 regulation of biomineral tissue development http://purl.obolibrary.org/obo/GO_2000026 regulation of multicellular organismal development Any process that modulates the frequency, rate or extent of biomineral tissue development, the formation of hard tissues that consist mainly of inorganic compounds. http://purl.obolibrary.org/obo/GO_0070168 negative regulation of biomineral tissue development http://purl.obolibrary.org/obo/GO_0070167 regulation of biomineral tissue development Any process that stops, prevents, or reduces the frequency, rate or extent of biomineral tissue development, the formation of hard tissues that consist mainly of inorganic compounds. http://purl.obolibrary.org/obo/GO_0070169 positive regulation of biomineral tissue development http://purl.obolibrary.org/obo/GO_0070167 regulation of biomineral tissue development Any process that activates or increases the frequency, rate or extent of biomineral tissue development, the formation of hard tissues that consist mainly of inorganic compounds. http://purl.obolibrary.org/obo/GO_0070405 ammonium ion binding http://purl.obolibrary.org/obo/GO_0043169 cation binding Binding to ammonium ions (NH4+). http://purl.obolibrary.org/obo/GO_0070542 response to fatty acid http://purl.obolibrary.org/obo/GO_0033993 response to lipid Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fatty acid stimulus. http://purl.obolibrary.org/obo/GO_0070587 regulation of cell-cell adhesion involved in gastrulation http://purl.obolibrary.org/obo/GO_0022407 regulation of cell-cell adhesion Any process that modulates the frequency, rate, or extent of attachment of a cell to another cell affecting gastrulation. http://purl.obolibrary.org/obo/GO_0070633 transepithelial transport http://purl.obolibrary.org/obo/GO_0006810 transport The directed movement of a substance from one side of an epithelium to the other. http://purl.obolibrary.org/obo/GO_0070663 regulation of leukocyte proliferation http://purl.obolibrary.org/obo/GO_0042127 regulation of cell population proliferation Any process that modulates the frequency, rate or extent of leukocyte proliferation. http://purl.obolibrary.org/obo/GO_0070664 negative regulation of leukocyte proliferation http://purl.obolibrary.org/obo/GO_0008285 negative regulation of cell population proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of leukocyte proliferation. http://purl.obolibrary.org/obo/GO_0070665 positive regulation of leukocyte proliferation http://purl.obolibrary.org/obo/GO_0070663 regulation of leukocyte proliferation Any process that activates or increases the frequency, rate or extent of leukocyte proliferation. http://purl.obolibrary.org/obo/GO_0070828 heterochromatin organization http://purl.obolibrary.org/obo/GO_0006325 chromatin organization Any process that results in the specification, formation or maintenance of the physical structure of eukaryotic heterochromatin, a compact and highly condensed form of chromatin. http://purl.obolibrary.org/obo/GO_0071345 cellular response to cytokine stimulus http://purl.obolibrary.org/obo/GO_0034097 response to cytokine Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokine stimulus. http://purl.obolibrary.org/obo/GO_0071375 cellular response to peptide hormone stimulus http://purl.obolibrary.org/obo/GO_0032870 cellular response to hormone stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide hormone stimulus. A peptide hormone is any of a class of peptides that are secreted into the blood stream and have endocrine functions in living animals. http://purl.obolibrary.org/obo/GO_0071451 cellular response to superoxide http://purl.obolibrary.org/obo/GO_0071450 cellular response to oxygen radical Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a superoxide stimulus. Superoxide is the anion, oxygen-, formed by addition of one electron to dioxygen (O2) or any compound containing the superoxide anion. http://purl.obolibrary.org/obo/GO_0071495 cellular response to endogenous stimulus http://purl.obolibrary.org/obo/GO_0009719 response to endogenous stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus arising within the organism. http://purl.obolibrary.org/obo/GO_0071600 otic vesicle morphogenesis http://purl.obolibrary.org/obo/GO_0060562 epithelial tube morphogenesis The process in which the anatomical structures of the otic vesicle are generated and organized. The otic vesicle is a transient embryonic structure formed during development of the vertebrate inner ear. http://purl.obolibrary.org/obo/GO_0071699 olfactory placode morphogenesis http://purl.obolibrary.org/obo/GO_0071697 ectodermal placode morphogenesis The process in which the anatomical structures of the olfactory placode are generated and organized. The olfactory placode is a thickening of the neural ectoderm in the head region of the vertebrate embryo which develops into the olfactory region of the nasal cavity. http://purl.obolibrary.org/obo/GO_0071706 tumor necrosis factor superfamily cytokine production http://purl.obolibrary.org/obo/GO_0001816 cytokine production The appearance of any member of the TNF superfamily due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. http://purl.obolibrary.org/obo/GO_0071763 nuclear membrane organization http://purl.obolibrary.org/obo/GO_0061024 membrane organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear inner or outer membrane. http://purl.obolibrary.org/obo/GO_0071825 protein-lipid complex organization http://purl.obolibrary.org/obo/GO_0043933 protein-containing complex organization Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein-lipid complex. http://purl.obolibrary.org/obo/GO_0071826 protein-RNA complex organization http://purl.obolibrary.org/obo/GO_0043933 protein-containing complex organization Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a ribonucleoprotein complex. http://purl.obolibrary.org/obo/GO_0072006 nephron development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the nephron over time, from its formation to the mature structure. A nephron is the functional unit of the kidney. http://purl.obolibrary.org/obo/GO_0072384 organelle transport along microtubule http://purl.obolibrary.org/obo/GO_0051656 establishment of organelle localization The directed movement of an organelle along a microtubule, mediated by motor proteins. This process begins with the attachment of an organelle to a microtubule, and ends when the organelle reaches its final destination. http://purl.obolibrary.org/obo/GO_0090031 positive regulation of steroid hormone biosynthetic process http://purl.obolibrary.org/obo/GO_0046886 positive regulation of hormone biosynthetic process Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroid hormones,compounds with a 1, 2, cyclopentanoperhydrophenanthrene nucleus that act as hormones. http://purl.obolibrary.org/obo/GO_0090066 regulation of anatomical structure size http://purl.obolibrary.org/obo/GO_0065008 regulation of biological quality Any process that modulates the size of an anatomical structure. http://purl.obolibrary.org/obo/GO_0090277 positive regulation of peptide hormone secretion http://purl.obolibrary.org/obo/GO_0090276 regulation of peptide hormone secretion Any process that increases the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules. http://purl.obolibrary.org/obo/GO_0090303 positive regulation of wound healing http://purl.obolibrary.org/obo/GO_0061041 regulation of wound healing Any process that increases the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury. http://purl.obolibrary.org/obo/GO_0090322 regulation of superoxide metabolic process http://purl.obolibrary.org/obo/GO_2000377 regulation of reactive oxygen species metabolic process Any process that modulates the rate, frequency, or extent of superoxide metabolism, the chemical reactions and pathways involving superoxide, the superoxide anion O2- (superoxide free radical), or any compound containing this species. http://purl.obolibrary.org/obo/GO_0097060 synaptic membrane http://purl.obolibrary.org/obo/GO_0098590 plasma membrane region A specialized area of membrane on either the presynaptic or the postsynaptic side of a synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell. http://purl.obolibrary.org/obo/GO_0097154 GABAergic neuron differentiation http://purl.obolibrary.org/obo/GO_0030182 neuron differentiation The process in which a neuroblast acquires the specialized structural and functional features of a GABAergic neuron. http://purl.obolibrary.org/obo/GO_0097644 calcitonin family binding http://purl.obolibrary.org/obo/GO_0017046 peptide hormone binding Binding to a member of the calcitonin family (e.g. adrenomedullin, adrenomedullin 2 (intermedin), amylin, calcitonin and calcitonin gene-related peptides (CGRPs)). http://purl.obolibrary.org/obo/GO_0097708 intracellular vesicle http://purl.obolibrary.org/obo/GO_0031982 vesicle Any vesicle that is part of the intracellular region. http://purl.obolibrary.org/obo/GO_0097722 sperm motility http://purl.obolibrary.org/obo/GO_0048870 cell motility Any process involved in the controlled movement of a sperm cell. http://purl.obolibrary.org/obo/GO_0097730 non-motile cilium http://purl.obolibrary.org/obo/GO_0005929 cilium A cilium which may have a variable array of axonemal microtubules but does not contain molecular motors. http://purl.obolibrary.org/obo/GO_0098711 iron ion import across plasma membrane http://purl.obolibrary.org/obo/GO_0098659 inorganic cation import across plasma membrane The directed movement of iron ions from outside of a cell, across the plasma membrane and into the cytosol. http://purl.obolibrary.org/obo/GO_0099501 exocytic vesicle membrane http://purl.obolibrary.org/obo/GO_0030658 transport vesicle membrane The lipid bilayer surrounding an exocytic vesicle. http://purl.obolibrary.org/obo/GO_0099503 secretory vesicle http://purl.obolibrary.org/obo/GO_0031410 cytoplasmic vesicle A cytoplasmic, membrane bound vesicle that is capable of fusing to the plasma membrane to release its contents into the extracellular space. http://purl.obolibrary.org/obo/GO_0099515 actin filament-based transport http://purl.obolibrary.org/obo/GO_0030705 cytoskeleton-dependent intracellular transport The transport of organelles or other particles from one location in the cell to another along actin filaments. http://purl.obolibrary.org/obo/GO_0099518 vesicle cytoskeletal trafficking http://purl.obolibrary.org/obo/GO_0030705 cytoskeleton-dependent intracellular transport The directed movement of a vesicle along a cytoskeletal fiber such as a microtubule or and actin filament, mediated by motor proteins. http://purl.obolibrary.org/obo/GO_1900046 regulation of hemostasis http://purl.obolibrary.org/obo/GO_0050878 regulation of body fluid levels Any process that modulates the frequency, rate or extent of hemostasis. http://purl.obolibrary.org/obo/GO_1900047 negative regulation of hemostasis http://purl.obolibrary.org/obo/GO_1900046 regulation of hemostasis Any process that stops, prevents or reduces the frequency, rate or extent of hemostasis. http://purl.obolibrary.org/obo/GO_1900048 positive regulation of hemostasis http://purl.obolibrary.org/obo/GO_1900046 regulation of hemostasis Any process that activates or increases the frequency, rate or extent of hemostasis. http://purl.obolibrary.org/obo/GO_1900371 regulation of purine nucleotide biosynthetic process http://purl.obolibrary.org/obo/GO_1900542 regulation of purine nucleotide metabolic process Any process that modulates the frequency, rate or extent of purine nucleotide biosynthetic processes. http://purl.obolibrary.org/obo/GO_1900372 negative regulation of purine nucleotide biosynthetic process http://purl.obolibrary.org/obo/GO_1900543 negative regulation of purine nucleotide metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of purine nucleotide biosynthetic processes. http://purl.obolibrary.org/obo/GO_1900373 positive regulation of purine nucleotide biosynthetic process http://purl.obolibrary.org/obo/GO_1900544 positive regulation of purine nucleotide metabolic process Any process that activates or increases the frequency, rate or extent of purine nucleotide biosynthetic processes. http://purl.obolibrary.org/obo/GO_1900542 regulation of purine nucleotide metabolic process http://purl.obolibrary.org/obo/GO_0006140 regulation of nucleotide metabolic process Any process that modulates the frequency, rate or extent of purine nucleotide metabolic process. http://purl.obolibrary.org/obo/GO_1900543 negative regulation of purine nucleotide metabolic process http://purl.obolibrary.org/obo/GO_1900542 regulation of purine nucleotide metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of purine nucleotide metabolic process. http://purl.obolibrary.org/obo/GO_1900544 positive regulation of purine nucleotide metabolic process http://purl.obolibrary.org/obo/GO_1900542 regulation of purine nucleotide metabolic process Any process that activates or increases the frequency, rate or extent of purine nucleotide metabolic process. http://purl.obolibrary.org/obo/GO_1901020 negative regulation of calcium ion transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0032413 negative regulation of ion transmembrane transporter activity Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion transmembrane transporter activity. http://purl.obolibrary.org/obo/GO_1901142 insulin metabolic process http://purl.obolibrary.org/obo/GO_0019538 protein metabolic process The chemical reactions and pathways involving insulin. http://purl.obolibrary.org/obo/GO_1901161 primary amino compound catabolic process http://purl.obolibrary.org/obo/GO_0009056 catabolic process The chemical reactions and pathways resulting in the breakdown of primary amino compound. http://purl.obolibrary.org/obo/GO_1901652 response to peptide http://purl.obolibrary.org/obo/GO_0042221 response to chemical Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide stimulus. http://purl.obolibrary.org/obo/GO_1901654 response to ketone http://purl.obolibrary.org/obo/GO_1901700 response to oxygen-containing compound A response that results in a state of tolerance to ketone. http://purl.obolibrary.org/obo/GO_1901879 regulation of protein depolymerization http://purl.obolibrary.org/obo/GO_0043244 regulation of protein-containing complex disassembly Any process that modulates the frequency, rate or extent of protein depolymerization. http://purl.obolibrary.org/obo/GO_1901881 positive regulation of protein depolymerization http://purl.obolibrary.org/obo/GO_0043243 positive regulation of protein-containing complex disassembly Any process that activates or increases the frequency, rate or extent of protein depolymerization. http://purl.obolibrary.org/obo/GO_1902679 negative regulation of RNA biosynthetic process http://purl.obolibrary.org/obo/GO_0051253 negative regulation of RNA metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of RNA biosynthetic process. http://purl.obolibrary.org/obo/GO_1902905 positive regulation of supramolecular fiber organization http://purl.obolibrary.org/obo/GO_0051130 positive regulation of cellular component organization Any process that activates or increases the frequency, rate or extent of supramolecular fiber organization. http://purl.obolibrary.org/obo/GO_1903008 organelle disassembly http://purl.obolibrary.org/obo/GO_0022411 cellular component disassembly The disaggregation of an organelle into its constituent components. http://purl.obolibrary.org/obo/GO_1903115 regulation of actin filament-based movement http://purl.obolibrary.org/obo/GO_0032970 regulation of actin filament-based process Any process that modulates the frequency, rate or extent of actin filament-based movement. http://purl.obolibrary.org/obo/GO_1903131 mononuclear cell differentiation http://purl.obolibrary.org/obo/GO_0002521 leukocyte differentiation The process in which a relatively unspecialized cell acquires the specialized features of a mononuclear cell. http://purl.obolibrary.org/obo/GO_1903314 regulation of nitrogen cycle metabolic process http://purl.obolibrary.org/obo/GO_0019222 regulation of metabolic process Any process that modulates the frequency, rate or extent of nitrogen cycle metabolic process. http://purl.obolibrary.org/obo/GO_1903353 regulation of nucleus organization http://purl.obolibrary.org/obo/GO_0033043 regulation of organelle organization Any process that modulates the frequency, rate or extent of nucleus organization. http://purl.obolibrary.org/obo/GO_1903555 regulation of tumor necrosis factor superfamily cytokine production http://purl.obolibrary.org/obo/GO_0001817 regulation of cytokine production Any process that modulates the frequency, rate or extent of tumor necrosis factor superfamily cytokine production. http://purl.obolibrary.org/obo/GO_1903556 negative regulation of tumor necrosis factor superfamily cytokine production http://purl.obolibrary.org/obo/GO_1903555 regulation of tumor necrosis factor superfamily cytokine production Any process that stops, prevents or reduces the frequency, rate or extent of tumor necrosis factor superfamily cytokine production. http://purl.obolibrary.org/obo/GO_1903557 positive regulation of tumor necrosis factor superfamily cytokine production http://purl.obolibrary.org/obo/GO_1903555 regulation of tumor necrosis factor superfamily cytokine production Any process that activates or increases the frequency, rate or extent of tumor necrosis factor superfamily cytokine production. http://purl.obolibrary.org/obo/GO_1903976 negative regulation of glial cell migration http://purl.obolibrary.org/obo/GO_1903975 regulation of glial cell migration Any process that stops, prevents or reduces the frequency, rate or extent of glial cell migration. http://purl.obolibrary.org/obo/GO_1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential http://purl.obolibrary.org/obo/GO_0022824 transmitter-gated monoatomic ion channel activity Any transmitter-gated ion channel activity that is involved in regulation of postsynaptic membrane potential. http://purl.obolibrary.org/obo/GO_1904936 interneuron migration http://purl.obolibrary.org/obo/GO_0001764 neuron migration The orderly movement of an interneuron from one site to another. http://purl.obolibrary.org/obo/GO_1905268 negative regulation of chromatin organization http://purl.obolibrary.org/obo/GO_0051129 negative regulation of cellular component organization Any process that stops, prevents or reduces the frequency, rate or extent of chromatin organization. http://purl.obolibrary.org/obo/GO_1905269 positive regulation of chromatin organization http://purl.obolibrary.org/obo/GO_2001252 positive regulation of chromosome organization Any process that activates or increases the frequency, rate or extent of chromatin organization. http://purl.obolibrary.org/obo/GO_1905332 positive regulation of morphogenesis of an epithelium http://purl.obolibrary.org/obo/GO_1905330 regulation of morphogenesis of an epithelium Any process that activates or increases the frequency, rate or extent of morphogenesis of an epithelium. http://purl.obolibrary.org/obo/GO_1905879 regulation of oogenesis http://purl.obolibrary.org/obo/GO_2000241 regulation of reproductive process Any process that modulates the frequency, rate or extent of oogenesis. http://purl.obolibrary.org/obo/GO_1905880 negative regulation of oogenesis http://purl.obolibrary.org/obo/GO_2000242 negative regulation of reproductive process Any process that stops, prevents or reduces the frequency, rate or extent of oogenesis. http://purl.obolibrary.org/obo/GO_1905881 positive regulation of oogenesis http://purl.obolibrary.org/obo/GO_2000243 positive regulation of reproductive process Any process that activates or increases the frequency, rate or extent of oogenesis. http://purl.obolibrary.org/obo/GO_1990266 neutrophil migration http://purl.obolibrary.org/obo/GO_0097530 granulocyte migration The movement of a neutrophil within or between different tissues and organs of the body. http://purl.obolibrary.org/obo/GO_1990351 transporter complex http://purl.obolibrary.org/obo/GO_0032991 protein-containing complex A protein complex facilitating transport of molecules (proteins, small molecules, nucleic acids) into, out of or within a cell, or between cells. http://purl.obolibrary.org/obo/GO_1990904 ribonucleoprotein complex http://purl.obolibrary.org/obo/GO_0032991 protein-containing complex A macromolecular complex that contains both RNA and protein molecules. http://purl.obolibrary.org/obo/GO_2000106 regulation of leukocyte apoptotic process http://purl.obolibrary.org/obo/GO_0042981 regulation of apoptotic process Any process that modulates the frequency, rate or extent of leukocyte apoptotic process. http://purl.obolibrary.org/obo/GO_2000107 negative regulation of leukocyte apoptotic process http://purl.obolibrary.org/obo/GO_2000106 regulation of leukocyte apoptotic process Any process that stops, prevents, or reduces the frequency, rate or extent of leukocyte apoptotic process. http://purl.obolibrary.org/obo/GO_2000108 positive regulation of leukocyte apoptotic process http://purl.obolibrary.org/obo/GO_0043065 positive regulation of apoptotic process Any process that activates or increases the frequency, rate or extent of leukocyte apoptotic process. http://purl.obolibrary.org/obo/GO_2000145 regulation of cell motility http://purl.obolibrary.org/obo/GO_0040012 regulation of locomotion Any process that modulates the frequency, rate or extent of cell motility. http://purl.obolibrary.org/obo/GO_2000146 negative regulation of cell motility http://purl.obolibrary.org/obo/GO_0040013 negative regulation of locomotion Any process that stops, prevents, or reduces the frequency, rate or extent of cell motility. http://purl.obolibrary.org/obo/GO_2000147 positive regulation of cell motility http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the frequency, rate or extent of cell motility. http://purl.obolibrary.org/obo/GO_2000177 regulation of neural precursor cell proliferation http://purl.obolibrary.org/obo/GO_0042127 regulation of cell population proliferation Any process that modulates the frequency, rate or extent of neural precursor cell proliferation. http://purl.obolibrary.org/obo/GO_2000278 regulation of DNA biosynthetic process http://purl.obolibrary.org/obo/GO_0051052 regulation of DNA metabolic process Any process that modulates the frequency, rate or extent of DNA biosynthetic process. http://purl.obolibrary.org/obo/GO_2000279 negative regulation of DNA biosynthetic process http://purl.obolibrary.org/obo/GO_2000278 regulation of DNA biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of DNA biosynthetic process. http://purl.obolibrary.org/obo/GO_2000573 positive regulation of DNA biosynthetic process http://purl.obolibrary.org/obo/GO_2000278 regulation of DNA biosynthetic process Any process that activates or increases the frequency, rate or extent of DNA biosynthetic process. http://purl.obolibrary.org/obo/GO_2000649 regulation of sodium ion transmembrane transporter activity http://purl.obolibrary.org/obo/GO_1902305 regulation of sodium ion transmembrane transport Any process that modulates the frequency, rate or extent of sodium ion transmembrane transporter activity. http://purl.obolibrary.org/obo/GO_2000651 positive regulation of sodium ion transmembrane transporter activity http://purl.obolibrary.org/obo/GO_1902307 positive regulation of sodium ion transmembrane transport Any process that activates or increases the frequency, rate or extent of sodium ion transmembrane transporter activity. http://purl.obolibrary.org/obo/GO_2001251 negative regulation of chromosome organization http://purl.obolibrary.org/obo/GO_0010639 negative regulation of organelle organization Any process that stops, prevents or reduces the frequency, rate or extent of chromosome organization. http://purl.obolibrary.org/obo/GO_2001252 positive regulation of chromosome organization http://purl.obolibrary.org/obo/GO_0010638 positive regulation of organelle organization Any process that activates or increases the frequency, rate or extent of chromosome organization. http://purl.obolibrary.org/obo/GO_2001259 positive regulation of cation channel activity http://purl.obolibrary.org/obo/GO_1904064 positive regulation of cation transmembrane transport Any process that activates or increases the frequency, rate or extent of cation channel activity. http://purl.obolibrary.org/obo/GO_0034293 sexual sporulation http://purl.obolibrary.org/obo/GO_0043934 sporulation The formation of spores derived from the products of meiosis. http://purl.obolibrary.org/obo/GO_0034295 basidiospore formation http://purl.obolibrary.org/obo/GO_0043935 sexual sporulation resulting in formation of a cellular spore The process in which spores form outside a specialized end cell known as a basidium. Basidia are characteristic of the basidiomycete fungi (phylum Basidiomycota), and give rise to spores that each contain a haploid nucleus that is the product of meiosis. The spores are usually attached to the basidium by short spikes called sterigmata (singular: sterigma). In most basidiomycetes there are four sterigmata (and four spores) to a basidium. http://purl.obolibrary.org/obo/GO_0034296 zygospore formation http://purl.obolibrary.org/obo/GO_0043935 sexual sporulation resulting in formation of a cellular spore The process in which zygospores are formed. Zygospores are characteristic of the zygomycete fungi (phylum Zygomycota) thick-walled and darkly colored, and usually heavily ornamented as well, with many spines or ridges. It is formed between two specialized organs called suspensors, which are themselves usually heavily ornamented, one from each mating partner. The zygospore forms between them and then breaks away. http://purl.obolibrary.org/obo/GO_0034306 regulation of sexual sporulation http://purl.obolibrary.org/obo/GO_0051445 regulation of meiotic cell cycle Any process that modulates the frequency, rate or extent of spore formation from the products of meiosis. An example of this is found in Saccharomyces cerevisiae. http://purl.obolibrary.org/obo/GO_0034330 cell junction organization http://purl.obolibrary.org/obo/GO_0016043 cellular component organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell junction. A cell junction is a specialized region of connection between two cells or between a cell and the extracellular matrix. http://purl.obolibrary.org/obo/GO_0034349 glial cell apoptotic process http://purl.obolibrary.org/obo/GO_0006915 apoptotic process Any apoptotic process in a glial cell, a non-neuronal cell of the nervous system. http://purl.obolibrary.org/obo/GO_0034350 regulation of glial cell apoptotic process http://purl.obolibrary.org/obo/GO_0042981 regulation of apoptotic process Any process that modulates the frequency, rate, or extent of glial cell apoptotic process. http://purl.obolibrary.org/obo/GO_0034351 negative regulation of glial cell apoptotic process http://purl.obolibrary.org/obo/GO_0034350 regulation of glial cell apoptotic process Any process that stops, prevents, or reduces the frequency, rate, or extent of glial cell apoptotic process. http://purl.obolibrary.org/obo/GO_0034352 positive regulation of glial cell apoptotic process http://purl.obolibrary.org/obo/GO_0043065 positive regulation of apoptotic process Any process that activates or increases the frequency, rate, or extent of glial cell apoptotic process. http://purl.obolibrary.org/obo/GO_0034390 smooth muscle cell apoptotic process http://purl.obolibrary.org/obo/GO_0010657 muscle cell apoptotic process Any apoptotic process in a smooth muscle cell. Smooth muscle consists of non-striated, elongated, spindle-shaped cell found lining the digestive tract, uterus, and blood vessels. http://purl.obolibrary.org/obo/GO_0034391 regulation of smooth muscle cell apoptotic process http://purl.obolibrary.org/obo/GO_0010660 regulation of muscle cell apoptotic process Any process that modulates the frequency, rate, or extent of smooth muscle cell apoptotic process. http://purl.obolibrary.org/obo/GO_0034392 negative regulation of smooth muscle cell apoptotic process http://purl.obolibrary.org/obo/GO_0010656 negative regulation of muscle cell apoptotic process Any process that stops, prevents, or reduces the frequency, rate, or extent of smooth muscle cell apoptotic process. http://purl.obolibrary.org/obo/GO_0034393 positive regulation of smooth muscle cell apoptotic process http://purl.obolibrary.org/obo/GO_0010661 positive regulation of muscle cell apoptotic process Any process that activates or increases the frequency, rate, or extent of smooth muscle cell apoptotic process. http://purl.obolibrary.org/obo/GO_0034436 glycoprotein transport http://purl.obolibrary.org/obo/GO_1901264 carbohydrate derivative transport The directed movement of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0034486 vacuolar transmembrane transport http://purl.obolibrary.org/obo/GO_0055085 transmembrane transport The process in which a solute is transported from one side of the vacuolar membrane to the other. http://purl.obolibrary.org/obo/GO_0034488 basic amino acid transmembrane export from vacuole http://purl.obolibrary.org/obo/GO_1990822 basic amino acid transmembrane transport The directed movement of basic amino acids out of the vacuole, across the vacuolar membrane. http://purl.obolibrary.org/obo/GO_0034489 neutral amino acid transmembrane export from vacuole http://purl.obolibrary.org/obo/GO_0032974 amino acid transmembrane export from vacuole The directed movement of neutral amino acids out of the vacuole, across the vacuolar membrane. http://purl.obolibrary.org/obo/GO_0034490 basic amino acid transmembrane import into vacuole http://purl.obolibrary.org/obo/GO_1990822 basic amino acid transmembrane transport The directed movement of basic amino acids into the vacuole across the vacuolar membrane. http://purl.obolibrary.org/obo/GO_0034491 neutral amino acid transmembrane import into vacuole http://purl.obolibrary.org/obo/GO_0032975 amino acid transmembrane import into vacuole The directed movement of neutral amino acids into the vacuole across the vacuolar membrane. http://purl.obolibrary.org/obo/GO_0034502 protein localization to chromosome http://purl.obolibrary.org/obo/GO_0033365 protein localization to organelle Any process in which a protein is transported to, or maintained at, a specific location on a chromosome. http://purl.obolibrary.org/obo/GO_0034505 tooth mineralization http://purl.obolibrary.org/obo/GO_0031214 biomineral tissue development The process in which calcium salts are deposited into calcareous tooth structures such as dental enamel, dentin and cementum. http://purl.obolibrary.org/obo/GO_0034614 cellular response to reactive oxygen species http://purl.obolibrary.org/obo/GO_1901701 cellular response to oxygen-containing compound Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals. http://purl.obolibrary.org/obo/GO_0034642 mitochondrion migration along actin filament http://purl.obolibrary.org/obo/GO_0051654 establishment of mitochondrion localization The directed movement of a mitochondrion along a microfilament, mediated by motor proteins. http://purl.obolibrary.org/obo/GO_0034643 establishment of mitochondrion localization, microtubule-mediated http://purl.obolibrary.org/obo/GO_0051654 establishment of mitochondrion localization The directed movement of the mitochondrion to a specific location, by a process involving microtubules. http://purl.obolibrary.org/obo/GO_0034672 anterior/posterior pattern specification involved in pronephros development http://purl.obolibrary.org/obo/GO_0009952 anterior/posterior pattern specification The developmental process that results in the creation of defined areas or spaces within the pronephros along the anterior/posterior axis to which cells respond and eventually are instructed to differentiate. http://purl.obolibrary.org/obo/GO_0034756 regulation of iron ion transport http://purl.obolibrary.org/obo/GO_0010959 regulation of metal ion transport Any process that modulates the frequency, rate or extent of the directed movement of iron ions (Fe) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0034757 negative regulation of iron ion transport http://purl.obolibrary.org/obo/GO_0043271 negative regulation of monoatomic ion transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of iron ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0034758 positive regulation of iron ion transport http://purl.obolibrary.org/obo/GO_0043270 positive regulation of monoatomic ion transport Any process that activates or increases the frequency, rate or extent of the directed movement of iron ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0034759 regulation of iron ion transmembrane transport http://purl.obolibrary.org/obo/GO_1904062 regulation of monoatomic cation transmembrane transport Any process that modulates the frequency, rate or extent of the directed movement of iron ions (Fe) from one side of a membrane to the other by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0034760 negative regulation of iron ion transmembrane transport http://purl.obolibrary.org/obo/GO_1904063 negative regulation of cation transmembrane transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of iron ions from one side of a membrane to the other by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0034761 positive regulation of iron ion transmembrane transport http://purl.obolibrary.org/obo/GO_1904064 positive regulation of cation transmembrane transport Any process that activates or increases the frequency, rate or extent of the directed movement of iron ions from one side of a membrane to the other by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0034763 negative regulation of transmembrane transport http://purl.obolibrary.org/obo/GO_0051051 negative regulation of transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0034764 positive regulation of transmembrane transport http://purl.obolibrary.org/obo/GO_0051050 positive regulation of transport Any process that activates or increases the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0034769 basement membrane disassembly http://purl.obolibrary.org/obo/GO_0022617 extracellular matrix disassembly The controlled breakdown of the basement membrane in the context of a normal process such as imaginal disc eversion. http://purl.obolibrary.org/obo/GO_0034776 response to histamine http://purl.obolibrary.org/obo/GO_1901698 response to nitrogen compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histamine stimulus. Histamine, the biogenic amine 2-(1H-imidazol-4-yl)ethanamine, is involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter. http://purl.obolibrary.org/obo/GO_0035010 encapsulation of foreign target http://purl.obolibrary.org/obo/GO_0002252 immune effector process Events resulting in the formation of a multilayered cellular sheath surrounding an invader and thus preventing its development. This defense mechanism is often seen in insects in response to nematodes or parasitoids, which are too large to be phagocytosed by individual hemocytes. In some organisms the capsule is blackened due to melanization. http://purl.obolibrary.org/obo/GO_0035019 somatic stem cell population maintenance http://purl.obolibrary.org/obo/GO_0019827 stem cell population maintenance Any process by which an organism retains a population of somatic stem cells, undifferentiated cells in the embryo or adult which can undergo unlimited division and give rise to cell types of the body other than those of the germ-line. http://purl.obolibrary.org/obo/GO_0035026 leading edge cell differentiation http://purl.obolibrary.org/obo/GO_0030855 epithelial cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features of leading edge cells, cells at the front of a migrating epithelial sheet. http://purl.obolibrary.org/obo/GO_0035039 male pronucleus assembly http://purl.obolibrary.org/obo/GO_0070925 organelle assembly The conversion at fertilization of the inactive sperm nucleus into a male pronucleus with its chromosomes processed for the first zygotic division. http://purl.obolibrary.org/obo/GO_0035040 sperm nuclear envelope removal http://purl.obolibrary.org/obo/GO_0051081 nuclear membrane disassembly Removal of the sperm nuclear envelope, allowing entry of maternal factors into the sperm nucleus. http://purl.obolibrary.org/obo/GO_0035045 sperm plasma membrane disassembly http://purl.obolibrary.org/obo/GO_0030397 membrane disassembly The gradual disintegration of the sperm plasma membrane following insemination. This process is seen in Drosophila after entry of the entire sperm, surrounded by its plasma membrane, into the egg. http://purl.obolibrary.org/obo/GO_0035099 hemocyte migration http://purl.obolibrary.org/obo/GO_0016477 cell migration The directed movement of a hemocyte within the embryo. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. In Drosophila, embryonic hemocytes originate from the head mesoderm as a cluster of cells. The cluster splits into two and one group of cells crosses the amnioserosa. Both populations then spread toward the middle of the embryo and then disperse evenly throughout the embryo. http://purl.obolibrary.org/obo/GO_0035136 forelimb morphogenesis http://purl.obolibrary.org/obo/GO_0035108 limb morphogenesis The process in which the anatomical structures of the forelimb are generated and organized. The forelimbs are the front limbs of an animal, e.g. the arms of a human. http://purl.obolibrary.org/obo/GO_0035137 hindlimb morphogenesis http://purl.obolibrary.org/obo/GO_0035108 limb morphogenesis The process in which the anatomical structures of the hindlimb are generated and organized. http://purl.obolibrary.org/obo/GO_0035148 tube formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis Creation of the central hole of a tube in an anatomical structure through which gases and/or liquids flow. http://purl.obolibrary.org/obo/GO_0035162 embryonic hemopoiesis http://purl.obolibrary.org/obo/GO_0048568 embryonic organ development The stages of blood cell formation that take place within the embryo. http://purl.obolibrary.org/obo/GO_0035163 embryonic hemocyte differentiation http://purl.obolibrary.org/obo/GO_0042386 hemocyte differentiation The process in which a relatively unspecialized cell derived from the embryonic head mesoderm acquires the specialized features of a mature hemocyte. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. http://purl.obolibrary.org/obo/GO_0035165 embryonic crystal cell differentiation http://purl.obolibrary.org/obo/GO_0042688 crystal cell differentiation The process in which an embryonic mesoderm-derived hemocyte precursor cell acquires the specialized features of a crystal cell. Crystal cells are a class of cells that contain crystalline inclusions and are involved in the melanization of pathogenic material in the hemolymph. http://purl.obolibrary.org/obo/GO_0035166 post-embryonic hemopoiesis http://purl.obolibrary.org/obo/GO_0030097 hemopoiesis The stages of blood cell formation that take place after completion of embryonic development. http://purl.obolibrary.org/obo/GO_0035167 larval lymph gland hemopoiesis http://purl.obolibrary.org/obo/GO_0035166 post-embryonic hemopoiesis The production of blood cells from the larval lymph gland. The lymph gland consists of three to six bilaterally paired lobes that are attached to the cardioblasts during larval stages, and it degenerates during pupal stages. http://purl.obolibrary.org/obo/GO_0035168 larval lymph gland hemocyte differentiation http://purl.obolibrary.org/obo/GO_0042386 hemocyte differentiation The process in which a relatively unspecialized cell derived from the larval lymph gland acquires the specialized features of a mature hemocyte. The lymph gland consists of three to six bilaterally paired lobes that are attached to the cardioblasts during larval stages, and it degenerates during pupal stages. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this process is found in Drosophila melanogaster. http://purl.obolibrary.org/obo/GO_0035169 lymph gland plasmatocyte differentiation http://purl.obolibrary.org/obo/GO_0042387 plasmatocyte differentiation The process in which a relatively unspecialized larval lymph gland-derived hemocyte precursor cell acquires the specialized features of the phagocytic blood-cell type, the plasmatocyte. http://purl.obolibrary.org/obo/GO_0035170 lymph gland crystal cell differentiation http://purl.obolibrary.org/obo/GO_0042688 crystal cell differentiation The process in which a relatively unspecialized larval lymph gland-derived hemocyte precursor cell acquires the specialized features of a crystal cell. Crystal cells are a class of cells that contain crystalline inclusions and are involved in the melanization of pathogenic material in the hemolymph. http://purl.obolibrary.org/obo/GO_0035171 lamellocyte differentiation http://purl.obolibrary.org/obo/GO_0035168 larval lymph gland hemocyte differentiation The process in which a relatively unspecialized hemocyte precursor cell acquires the specialized features of a lamellocyte. Lamellocytes are a hemocyte lineage that exists only in larvae, but are seldom observed in healthy animals. Lamellocytes differentiate massively in the lymph glands after parasitization and are large flat cells devoted to encapsulation of invaders too large to be phagocytosed by plasmatocytes. http://purl.obolibrary.org/obo/GO_0035172 hemocyte proliferation http://purl.obolibrary.org/obo/GO_0008283 cell population proliferation The multiplication or reproduction of hemocytes, resulting in the expansion of the cell population. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. http://purl.obolibrary.org/obo/GO_0035190 syncytial nuclear migration http://purl.obolibrary.org/obo/GO_0007097 nuclear migration The directed movement of nuclei within the syncytial embryo of insects. These precise temporal and spatial patterns of nuclear movement are coordinated with mitotic divisions and are required during blastoderm formation to reposition dividing nuclei from the interior of the syncytial embryo to the cortex. http://purl.obolibrary.org/obo/GO_0035203 regulation of lamellocyte differentiation http://purl.obolibrary.org/obo/GO_1903706 regulation of hemopoiesis Any process that modulates the frequency, rate or extent of lamellocyte differentiation. Lamellocytes differentiate massively in the lymph glands after parasitization and are large flat cells devoted to encapsulation of invaders too large to be phagocytosed by plasmatocytes. http://purl.obolibrary.org/obo/GO_0035204 negative regulation of lamellocyte differentiation http://purl.obolibrary.org/obo/GO_0045611 negative regulation of hemocyte differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of lamellocyte differentiation. Lamellocytes differentiate massively in the lymph glands after parasitization and are large flat cells devoted to encapsulation of invaders too large to be phagocytosed by plasmatocytes. http://purl.obolibrary.org/obo/GO_0035205 positive regulation of lamellocyte differentiation http://purl.obolibrary.org/obo/GO_0045612 positive regulation of hemocyte differentiation Any process that activates or increases the frequency, rate or extent of lamellocyte differentiation. Lamellocytes differentiate massively in the lymph glands after parasitization and are large flat cells devoted to encapsulation of invaders too large to be phagocytosed by plasmatocytes. http://purl.obolibrary.org/obo/GO_0035206 regulation of hemocyte proliferation http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of hemocyte proliferation. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this is found in Drosophila melanogaster. http://purl.obolibrary.org/obo/GO_0035207 negative regulation of hemocyte proliferation http://purl.obolibrary.org/obo/GO_0008285 negative regulation of cell population proliferation Any process that stops, prevents or reduces the rate or extent of hemocyte proliferation. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this is found in Drosophila melanogaster. http://purl.obolibrary.org/obo/GO_0035208 positive regulation of hemocyte proliferation http://purl.obolibrary.org/obo/GO_0035206 regulation of hemocyte proliferation Any process that activates or increases the rate or extent of hemocyte proliferation. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) that are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this process is found in Drosophila melanogaster. http://purl.obolibrary.org/obo/GO_0035234 ectopic germ cell programmed cell death http://purl.obolibrary.org/obo/GO_0010623 programmed cell death involved in cell development Programmed cell death of an errant germ line cell that is outside the normal migratory path or ectopic to the gonad. This is an important mechanism of regulating germ cell survival within the embryo. http://purl.obolibrary.org/obo/GO_0035249 synaptic transmission, glutamatergic http://purl.obolibrary.org/obo/GO_0007268 chemical synaptic transmission The vesicular release of glutamate from a presynapse, across a chemical synapse, the subsequent activation of glutamate receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse. http://purl.obolibrary.org/obo/GO_0035260 internal genitalia morphogenesis http://purl.obolibrary.org/obo/GO_0035112 genitalia morphogenesis The process in which the anatomical structures of the internal genitalia are generated and organized. The internal genitalia are the internal sex organs such as the uterine tube, the uterus and the vagina in female mammals, and the testis, seminal vesicle, ejaculatory duct and prostate in male mammals. http://purl.obolibrary.org/obo/GO_0035261 external genitalia morphogenesis http://purl.obolibrary.org/obo/GO_0035112 genitalia morphogenesis The process in which the anatomical structures of the external genitalia are generated and organized. The external genitalia are the outer sex organs, such as the penis or vulva in mammals. http://purl.obolibrary.org/obo/GO_0035262 gonad morphogenesis http://purl.obolibrary.org/obo/GO_0009887 animal organ morphogenesis The process in which the anatomical structures of the gonads are generated and organized. A gonad is an animal organ producing gametes, e.g. the testes or the ovary in mammals. http://purl.obolibrary.org/obo/GO_0035264 multicellular organism growth http://purl.obolibrary.org/obo/GO_0048589 developmental growth The increase in size or mass of an entire multicellular organism, as opposed to cell growth. http://purl.obolibrary.org/obo/GO_0035290 trunk segmentation http://purl.obolibrary.org/obo/GO_0035282 segmentation Partitioning of the blastoderm embryo into trunk segmental units. In Drosophila, the trunk segments include thoracic segments and abdominal segments A1 to A8. http://purl.obolibrary.org/obo/GO_0035315 hair cell differentiation http://purl.obolibrary.org/obo/GO_0030182 neuron differentiation The process in which a relatively unspecialized cell acquires specialized features of a hair cell. http://purl.obolibrary.org/obo/GO_0035316 non-sensory hair organization http://purl.obolibrary.org/obo/GO_0120036 plasma membrane bounded cell projection organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of non-sensory hairs. These hairs are polarized cellular extensions that cover much of the insect epidermis. http://purl.obolibrary.org/obo/GO_0035369 pre-B cell receptor complex http://purl.obolibrary.org/obo/GO_0098796 membrane protein complex An immunoglobulin-like complex that is present in at least the plasma membrane of pre-B cells, and that is composed of two identical immunoglobulin heavy chains and two surrogate light chains, each composed of the lambda-5 and VpreB proteins, and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins. http://purl.obolibrary.org/obo/GO_0035372 protein localization to microtubule http://purl.obolibrary.org/obo/GO_0072698 protein localization to microtubule cytoskeleton A process in which a protein is transported to, or maintained at, a microtubule. http://purl.obolibrary.org/obo/GO_0035374 chondroitin sulfate binding http://purl.obolibrary.org/obo/GO_1901681 sulfur compound binding Binding to chondroitin sulfate, a glycosaminoglycan made up of two alternating monosaccharides: D-glucuronic acid (GlcA) and N-acetyl-D-galactosamine (GalNAc). http://purl.obolibrary.org/obo/GO_0035377 transepithelial water transport http://purl.obolibrary.org/obo/GO_0042045 epithelial fluid transport The directed movement of water (H2O) from one side of an epithelium to the other. http://purl.obolibrary.org/obo/GO_0035418 protein localization to synapse http://purl.obolibrary.org/obo/GO_1902414 protein localization to cell junction Any process in which a protein is transported to, and/or maintained at the synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell. http://purl.obolibrary.org/obo/GO_0035441 cell migration involved in vasculogenesis http://purl.obolibrary.org/obo/GO_0016477 cell migration The orderly movement of a cell from one site to another that will contribute to the differentiation of an endothelial cell that will form de novo blood vessels and tubes. http://purl.obolibrary.org/obo/GO_0035490 regulation of leukotriene production involved in inflammatory response http://purl.obolibrary.org/obo/GO_0051239 regulation of multicellular organismal process Any process that modulates the rate, frequency or extent of the synthesis or release of any leukotriene following a stimulus as part of an inflammatory response. http://purl.obolibrary.org/obo/GO_0035491 positive regulation of leukotriene production involved in inflammatory response http://purl.obolibrary.org/obo/GO_0035490 regulation of leukotriene production involved in inflammatory response Any process that increases the rate, frequency or extent of the synthesis or release of any leukotriene following a stimulus as part of an inflammatory response. http://purl.obolibrary.org/obo/GO_0035493 SNARE complex assembly http://purl.obolibrary.org/obo/GO_0065003 protein-containing complex assembly The aggregation, arrangement and bonding together of a set of components to form a SNARE complex, a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers. http://purl.obolibrary.org/obo/GO_0035494 SNARE complex disassembly http://purl.obolibrary.org/obo/GO_0032984 protein-containing complex disassembly The disaggregation of the SNARE protein complex into its constituent components. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers. http://purl.obolibrary.org/obo/GO_0035495 regulation of SNARE complex disassembly http://purl.obolibrary.org/obo/GO_0043244 regulation of protein-containing complex disassembly Any process that modulates the frequency, rate or extent of disassembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers. http://purl.obolibrary.org/obo/GO_0035540 positive regulation of SNARE complex disassembly http://purl.obolibrary.org/obo/GO_0051050 positive regulation of transport Any process that increases the frequency, rate or extent of disassembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers. http://purl.obolibrary.org/obo/GO_0035541 negative regulation of SNARE complex disassembly http://purl.obolibrary.org/obo/GO_0051051 negative regulation of transport Any process that decreases the frequency, rate or extent of disassembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers. http://purl.obolibrary.org/obo/GO_0035542 regulation of SNARE complex assembly http://purl.obolibrary.org/obo/GO_0043254 regulation of protein-containing complex assembly Any process that modulates the frequency, rate or extent of assembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers. http://purl.obolibrary.org/obo/GO_0035543 positive regulation of SNARE complex assembly http://purl.obolibrary.org/obo/GO_0035542 regulation of SNARE complex assembly Any process that increases the frequency, rate or extent of assembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers. http://purl.obolibrary.org/obo/GO_0035544 negative regulation of SNARE complex assembly http://purl.obolibrary.org/obo/GO_0035542 regulation of SNARE complex assembly Any process that decreases the frequency, rate or extent of assembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers. http://purl.obolibrary.org/obo/GO_0035562 negative regulation of chromatin binding http://purl.obolibrary.org/obo/GO_0051100 negative regulation of binding Any process that stops or reduces the frequency, rate or extent of chromatin binding. Chromatin binding is the selective interaction with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase. http://purl.obolibrary.org/obo/GO_0035563 positive regulation of chromatin binding http://purl.obolibrary.org/obo/GO_0051099 positive regulation of binding Any process that increases the frequency, rate or extent of chromatin binding. Chromatin binding is the selective interaction with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase. http://purl.obolibrary.org/obo/GO_0035577 azurophil granule membrane http://purl.obolibrary.org/obo/GO_0030667 secretory granule membrane The lipid bilayer surrounding an azurophil granule, a primary lysosomal granule found in neutrophil granulocytes that contains a wide range of hydrolytic enzymes and is released into the extracellular fluid. http://purl.obolibrary.org/obo/GO_0035589 G protein-coupled purinergic nucleotide receptor signaling pathway http://purl.obolibrary.org/obo/GO_0035590 purinergic nucleotide receptor signaling pathway A G protein-coupled receptor signaling pathway initiated by an extracellular purine nucleotide binding to its receptor, and ending with the regulation of a downstream cellular process. http://purl.obolibrary.org/obo/GO_0035592 establishment of protein localization to extracellular region http://purl.obolibrary.org/obo/GO_0045184 establishment of protein localization The directed movement of a protein to a specific location within the extracellular region. http://purl.obolibrary.org/obo/GO_0035622 intrahepatic bile duct development http://purl.obolibrary.org/obo/GO_0061009 common bile duct development The progression of the intrahepatic bile ducts over time, from their formation to the mature structure. Intrahepatic bile ducts (bile ducts within the liver) collect bile from bile canaliculi in the liver, and connect to the extrahepatic bile ducts (bile ducts outside the liver). http://purl.obolibrary.org/obo/GO_0035628 cystic duct development http://purl.obolibrary.org/obo/GO_0061009 common bile duct development The progression of the cystic duct over time, from its formation to the mature structure. The cystic duct runs from the gallbladder to the common bile duct. http://purl.obolibrary.org/obo/GO_0035630 bone mineralization involved in bone maturation http://purl.obolibrary.org/obo/GO_0030282 bone mineralization The deposition of hydroxyapatite, involved in the progression of the skeleton from its formation to its mature state. http://purl.obolibrary.org/obo/GO_0035645 enteric smooth muscle cell differentiation http://purl.obolibrary.org/obo/GO_0051145 smooth muscle cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell of the intestine. http://purl.obolibrary.org/obo/GO_0035675 neuromast hair cell development http://purl.obolibrary.org/obo/GO_0048666 neuron development The process whose specific outcome is the progression of a neuromast hair cell over time, from its formation to the mature structure. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. Cell development does not include the steps involved in committing a cell to a specific fate. http://purl.obolibrary.org/obo/GO_0035676 anterior lateral line neuromast hair cell development http://purl.obolibrary.org/obo/GO_0035675 neuromast hair cell development The process whose specific outcome is the progression of an anterior lateral line neuromast hair cell over time, from its formation to the mature structure. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. Cell development does not include the steps involved in committing a cell to a specific fate. http://purl.obolibrary.org/obo/GO_0035677 posterior lateral line neuromast hair cell development http://purl.obolibrary.org/obo/GO_0035675 neuromast hair cell development The process whose specific outcome is the progression of a posterior lateral line neuromast hair cell over time, from its formation to the mature structure. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. Cell development does not include the steps involved in committing a cell to a specific fate. http://purl.obolibrary.org/obo/GO_0035678 neuromast hair cell morphogenesis http://purl.obolibrary.org/obo/GO_0048667 cell morphogenesis involved in neuron differentiation The change in form (cell shape and size) that occurs when a neuromast hair cell progresses from its initial formation to its mature state. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. http://purl.obolibrary.org/obo/GO_0035694 mitochondrial protein catabolic process http://purl.obolibrary.org/obo/GO_0030163 protein catabolic process The chemical reactions and pathways resulting in the breakdown of a mitochondrial protein. This process is necessary to maintain the healthy state of mitochondria and is thought to occur via the induction of an intramitochondrial lysosome-like organelle that acts to eliminate the damaged oxidised mitochondrial proteins without destroying the mitochondrial structure. http://purl.obolibrary.org/obo/GO_0035700 astrocyte chemotaxis http://purl.obolibrary.org/obo/GO_0043615 astrocyte cell migration The directed movement of an astrocyte guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis). http://purl.obolibrary.org/obo/GO_0035701 hematopoietic stem cell migration http://purl.obolibrary.org/obo/GO_0016477 cell migration The orderly movement of a hematopoietic stem cell from one site to another. A hematopoietic stem cell is a cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system. http://purl.obolibrary.org/obo/GO_0035702 monocyte homeostasis http://purl.obolibrary.org/obo/GO_0002262 myeloid cell homeostasis The process of regulating the proliferation and elimination of monocytes such that the total number of monocytes within a whole or part of an organism is stable over time in the absence of an outside stimulus. http://purl.obolibrary.org/obo/GO_0035704 helper T cell chemotaxis http://purl.obolibrary.org/obo/GO_0010818 T cell chemotaxis The directed movement of a helper T cell in response to an external stimulus. http://purl.obolibrary.org/obo/GO_0035705 T-helper 17 cell chemotaxis http://purl.obolibrary.org/obo/GO_0010818 T cell chemotaxis The directed movement of a T-helper 17 cell in response to an external stimulus. http://purl.obolibrary.org/obo/GO_0035706 T-helper 1 cell chemotaxis http://purl.obolibrary.org/obo/GO_0010818 T cell chemotaxis The directed movement of a T-helper 1 cell in response to an external stimulus. http://purl.obolibrary.org/obo/GO_0035707 T-helper 2 cell chemotaxis http://purl.obolibrary.org/obo/GO_0010818 T cell chemotaxis The directed movement of a T-helper 2 cell in response to an external stimulus. http://purl.obolibrary.org/obo/GO_0035709 memory T cell activation http://purl.obolibrary.org/obo/GO_0042110 T cell activation The change in morphology and behavior of a memory T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. http://purl.obolibrary.org/obo/GO_0035710 CD4-positive, alpha-beta T cell activation http://purl.obolibrary.org/obo/GO_0046631 alpha-beta T cell activation The change in morphology and behavior of a CD4-positive, alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. http://purl.obolibrary.org/obo/GO_0035711 T-helper 1 cell activation http://purl.obolibrary.org/obo/GO_0035710 CD4-positive, alpha-beta T cell activation The change in morphology and behavior of a T-helper 1 cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. http://purl.obolibrary.org/obo/GO_0035712 T-helper 2 cell activation http://purl.obolibrary.org/obo/GO_0035710 CD4-positive, alpha-beta T cell activation The change in morphology and behavior of a T helper 2 cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. http://purl.obolibrary.org/obo/GO_0035719 tRNA import into nucleus http://purl.obolibrary.org/obo/GO_0051031 tRNA transport The directed movement of tRNA from the cytoplasm to the nucleus. http://purl.obolibrary.org/obo/GO_0035733 hepatic stellate cell activation http://purl.obolibrary.org/obo/GO_0072537 fibroblast activation A change in the morphology or behavior of a hepatic stellate cell resulting from exposure to a cytokine, chemokine, hormone, cellular ligand or soluble factor. http://purl.obolibrary.org/obo/GO_0035735 intraciliary transport involved in cilium assembly http://purl.obolibrary.org/obo/GO_0042073 intraciliary transport The bidirectional movement of large protein complexes along microtubules within a cilium that contributes to cilium assembly. http://purl.obolibrary.org/obo/GO_0035736 cell proliferation involved in compound eye morphogenesis http://purl.obolibrary.org/obo/GO_0008283 cell population proliferation The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to compound eye morphogenesis. http://purl.obolibrary.org/obo/GO_0035739 CD4-positive, alpha-beta T cell proliferation http://purl.obolibrary.org/obo/GO_0035710 CD4-positive, alpha-beta T cell activation The expansion of a CD4-positive, alpha-beta T cell population by cell division. http://purl.obolibrary.org/obo/GO_0035740 CD8-positive, alpha-beta T cell proliferation http://purl.obolibrary.org/obo/GO_0036037 CD8-positive, alpha-beta T cell activation The expansion of a CD8-positive, alpha-beta T cell population by cell division. http://purl.obolibrary.org/obo/GO_0035741 activated CD4-positive, alpha-beta T cell proliferation http://purl.obolibrary.org/obo/GO_0035739 CD4-positive, alpha-beta T cell proliferation The expansion of an activated CD4-positive, alpha-beta T cell population by cell division. http://purl.obolibrary.org/obo/GO_0035742 activated CD8-positive, alpha-beta T cell proliferation http://purl.obolibrary.org/obo/GO_0035740 CD8-positive, alpha-beta T cell proliferation The expansion of an activated CD8-positive, alpha-beta T cell population by cell division. http://purl.obolibrary.org/obo/GO_0035743 CD4-positive, alpha-beta T cell cytokine production http://purl.obolibrary.org/obo/GO_0002369 T cell cytokine production Any process that contributes to cytokine production by a CD4-positive, alpha-beta T cell. http://purl.obolibrary.org/obo/GO_0035744 T-helper 1 cell cytokine production http://purl.obolibrary.org/obo/GO_0035743 CD4-positive, alpha-beta T cell cytokine production Any process that contributes to cytokine production by a T-helper 1 cell. http://purl.obolibrary.org/obo/GO_0035745 T-helper 2 cell cytokine production http://purl.obolibrary.org/obo/GO_0035743 CD4-positive, alpha-beta T cell cytokine production Any process that contributes to cytokine production by a T-helper 2 cell. http://purl.obolibrary.org/obo/GO_0035747 natural killer cell chemotaxis http://purl.obolibrary.org/obo/GO_0048247 lymphocyte chemotaxis The directed movement of a natural killer cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis). http://purl.obolibrary.org/obo/GO_0035754 B cell chemotaxis http://purl.obolibrary.org/obo/GO_0048247 lymphocyte chemotaxis The directed movement of a B cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis). http://purl.obolibrary.org/obo/GO_0035767 endothelial cell chemotaxis http://purl.obolibrary.org/obo/GO_0043542 endothelial cell migration The directed movement of an endothelial cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis). http://purl.obolibrary.org/obo/GO_0035773 insulin secretion involved in cellular response to glucose stimulus http://purl.obolibrary.org/obo/GO_0030073 insulin secretion The regulated release of proinsulin from secretory granules (B granules) in the B cells of the pancreas; accompanied by cleavage of proinsulin to form mature insulin, in response to a glucose stimulus. http://purl.obolibrary.org/obo/GO_0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus http://purl.obolibrary.org/obo/GO_0061178 regulation of insulin secretion involved in cellular response to glucose stimulus Any process that increases the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose. http://purl.obolibrary.org/obo/GO_0035775 pronephric glomerulus morphogenesis http://purl.obolibrary.org/obo/GO_0072102 glomerulus morphogenesis The process in which the anatomical structures of the pronephric glomerulus are generated and organized. The pronephric glomerulus is part of the pronephric nephron and is restricted to one body segment. http://purl.obolibrary.org/obo/GO_0035776 pronephric proximal tubule development http://purl.obolibrary.org/obo/GO_0072014 proximal tubule development The progression of the pronephric proximal tubule over time, from its formation to the mature structure. A pronephric nephron tubule is an epithelial tube that is part of the pronephros. http://purl.obolibrary.org/obo/GO_0035777 pronephric distal tubule development http://purl.obolibrary.org/obo/GO_0072017 distal tubule development The process whose specific outcome is the progression of the pronephric distal tubule over time, from its formation to the mature structure. A pronephric nephron tubule is an epithelial tube that is part of the pronephros. http://purl.obolibrary.org/obo/GO_0035778 pronephric nephron tubule epithelial cell differentiation http://purl.obolibrary.org/obo/GO_0072160 nephron tubule epithelial cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the pronephric nephron tubule as it progresses from its formation to the mature state. http://purl.obolibrary.org/obo/GO_0035779 angioblast cell differentiation http://purl.obolibrary.org/obo/GO_0048863 stem cell differentiation The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an angioblast cell. Angioblasts are one of the two products formed from hemangioblast cells (the other being pluripotent hemopoietic stem cells). http://purl.obolibrary.org/obo/GO_0035787 cell migration involved in kidney development http://purl.obolibrary.org/obo/GO_0016477 cell migration The orderly movement of a cell from one site to another that will contribute to the progression of the kidney over time, from its formation to the mature organ. http://purl.obolibrary.org/obo/GO_0035788 cell migration involved in metanephros development http://purl.obolibrary.org/obo/GO_0035787 cell migration involved in kidney development The orderly movement of a cell from one site to another that will contribute to the progression of the metanephric kidney over time, from its formation to the mature organ. http://purl.obolibrary.org/obo/GO_0035799 ureter maturation http://purl.obolibrary.org/obo/GO_0048799 animal organ maturation A developmental process, independent of morphogenetic (shape) change, that is required for the ureter to attain its fully functional state. The ureter is a muscular tube that transports urine from the kidney to the urinary bladder or from the Malpighian tubule to the hindgut. http://purl.obolibrary.org/obo/GO_0035801 adrenal cortex development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the adrenal cortex over time, from its formation to the mature structure. The adrenal cortex is located at the periphery of the adrenal gland and controls glucose and electrolyte metabolism, response to stress and sexual development through the production of different classes of steroid hormones (glucocorticoids, mineralocorticoids and androgens). http://purl.obolibrary.org/obo/GO_0035802 adrenal cortex formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process that gives rise to the adrenal cortex. This process pertains to the initial formation of a structure from unspecified parts. The adrenogonadal primordium from which the adrenal cortex is formed derives from a condensation of coelomic epithelial cells (the urogenital ridge; the same structure from which gonads and kidney also originate). http://purl.obolibrary.org/obo/GO_0035809 regulation of urine volume http://purl.obolibrary.org/obo/GO_0050878 regulation of body fluid levels Any process that modulates the amount of urine excreted from the body over a unit of time. http://purl.obolibrary.org/obo/GO_0035844 cloaca development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the cloaca over time, from it's formation to the mature structure. The cloaca is the common chamber into which intestinal, genital and urinary canals open in vertebrates. http://purl.obolibrary.org/obo/GO_0035846 oviduct epithelium development http://purl.obolibrary.org/obo/GO_0060429 epithelium development The progression of the oviduct epithelium over time from its initial formation to the mature structure. An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism. The oviduct epithelium is the specialized epithelium that lines the oviduct. http://purl.obolibrary.org/obo/GO_0035847 uterine epithelium development http://purl.obolibrary.org/obo/GO_0035846 oviduct epithelium development The progression of an epithelium of the uterus over time from its initial formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. http://purl.obolibrary.org/obo/GO_0035848 oviduct morphogenesis http://purl.obolibrary.org/obo/GO_0009887 animal organ morphogenesis The process in which anatomical structures of the oviduct are generated and organized. An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism. http://purl.obolibrary.org/obo/GO_0035855 megakaryocyte development http://purl.obolibrary.org/obo/GO_0061515 myeloid cell development The process whose specific outcome is the progression of a megakaryocyte cell over time, from its formation to the mature structure. Megakaryocyte development does not include the steps involved in committing a cell to a megakaryocyte fate. A megakaryocyte is a giant cell 50 to 100 micron in diameter, with a greatly lobulated nucleus, found in the bone marrow. http://purl.obolibrary.org/obo/GO_0035864 response to potassium ion http://purl.obolibrary.org/obo/GO_0010038 response to metal ion Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a potassium ion stimulus. http://purl.obolibrary.org/obo/GO_0035865 cellular response to potassium ion http://purl.obolibrary.org/obo/GO_0035864 response to potassium ion Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a potassium ion stimulus. http://purl.obolibrary.org/obo/GO_0035878 nail development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of a nail over time, from its formation to the mature structure. A nail is a horn-like envelope covering the outer end of a finger or toe, and consists of the nail plate, the nail matrix and the nail bed below it, and the grooves surrounding it. http://purl.obolibrary.org/obo/GO_0035881 amacrine cell differentiation http://purl.obolibrary.org/obo/GO_0021953 central nervous system neuron differentiation The process in which a relatively unspecialized cell acquires specialized features of an amacrine cell, an interneuron generated in the inner nuclear layer (INL) of the vertebrate retina. Amacrine cells integrate, modulate, and interpose a temporal domain in the visual message presented to the retinal ganglion cells, with which they synapse in the inner plexiform layer. Amacrine cells lack large axons. http://purl.obolibrary.org/obo/GO_0035886 vascular associated smooth muscle cell differentiation http://purl.obolibrary.org/obo/GO_0051145 smooth muscle cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a vascular smooth muscle cell. http://purl.obolibrary.org/obo/GO_0035887 aortic smooth muscle cell differentiation http://purl.obolibrary.org/obo/GO_0035886 vascular associated smooth muscle cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell surrounding the aorta. http://purl.obolibrary.org/obo/GO_0035898 parathyroid hormone secretion http://purl.obolibrary.org/obo/GO_0060986 endocrine hormone secretion The regulated release of parathyroid hormone into the circulatory system. http://purl.obolibrary.org/obo/GO_0035904 aorta development http://purl.obolibrary.org/obo/GO_0060840 artery development The progression of the aorta over time, from its initial formation to the mature structure. An aorta is an artery that carries blood from the heart to other parts of the body. http://purl.obolibrary.org/obo/GO_0035905 ascending aorta development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the ascending aorta over time, from its initial formation to the mature structure. The ascending aorta is the portion of the aorta in a two-pass circulatory system that lies between the heart and the arch of aorta. In a two-pass circulatory system blood passes twice through the heart to supply the body once. http://purl.obolibrary.org/obo/GO_0035906 descending aorta development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the descending aorta over time, from its initial formation to the mature structure. The descending aorta is the portion of the aorta in a two-pass circulatory system from the arch of aorta to the point where it divides into the common iliac arteries. In a two-pass circulatory system blood passes twice through the heart to supply the body once. http://purl.obolibrary.org/obo/GO_0035907 dorsal aorta development http://purl.obolibrary.org/obo/GO_0035904 aorta development The progression of the dorsal aorta over time, from its initial formation to the mature structure. The dorsal aorta is a blood vessel in a single-pass circulatory system that carries oxygenated blood from the gills to the rest of the body. In a single-pass circulatory system blood passes once through the heart to supply the body once. http://purl.obolibrary.org/obo/GO_0035909 aorta morphogenesis http://purl.obolibrary.org/obo/GO_0048844 artery morphogenesis The process in which the anatomical structures of an aorta are generated and organized. An aorta is an artery that carries blood from the heart to other parts of the body. http://purl.obolibrary.org/obo/GO_0035910 ascending aorta morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structures of the ascending aorta are generated and organized. The ascending aorta is the portion of the aorta in a two-pass circulatory system that lies between the heart and the arch of aorta. In a two-pass circulatory system blood passes twice through the heart to supply the body once. http://purl.obolibrary.org/obo/GO_0035911 descending aorta morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structures of the descending aorta are generated and organized. The descending aorta is the portion of the aorta in a two-pass circulatory system from the arch of aorta to the point where it divides into the common iliac arteries. In a two-pass circulatory system blood passes twice through the heart to supply the body once. http://purl.obolibrary.org/obo/GO_0035912 dorsal aorta morphogenesis http://purl.obolibrary.org/obo/GO_0035909 aorta morphogenesis The process in which the anatomical structures of the dorsal aorta are generated and organized. The dorsal aorta is a blood vessel in a single-pass circulatory system that carries oxygenated blood from the gills to the rest of the body. In a single-pass circulatory system blood passes once through the heart to supply the body once. http://purl.obolibrary.org/obo/GO_0035921 desmosome disassembly http://purl.obolibrary.org/obo/GO_0150147 cell-cell junction disassembly The controlled breakdown of a desmosome. A desmosome is a patch-like intercellular junction found in vertebrate tissues, consisting of parallel zones of two cell membranes, separated by an space of 25-35 nm, and having dense fibrillar plaques in the subjacent cytoplasm. http://purl.obolibrary.org/obo/GO_0035929 steroid hormone secretion http://purl.obolibrary.org/obo/GO_0140353 lipid export from cell The regulated release of any steroid that acts as a hormone into the circulatory system. http://purl.obolibrary.org/obo/GO_0035930 corticosteroid hormone secretion http://purl.obolibrary.org/obo/GO_0035929 steroid hormone secretion The regulated release of any corticosteroid hormone into the circulatory system. http://purl.obolibrary.org/obo/GO_0035931 mineralocorticoid secretion http://purl.obolibrary.org/obo/GO_0035930 corticosteroid hormone secretion The regulated release of any mineralocorticoid into the circulatory system. Mineralocorticoids are a class of steroid hormones that regulate water and electrolyte metabolism. http://purl.obolibrary.org/obo/GO_0035933 glucocorticoid secretion http://purl.obolibrary.org/obo/GO_0035930 corticosteroid hormone secretion The regulated release of any glucocorticoid hormone into the circulatory system. Glucocorticoids are a class of steroid hormones that regulate a variety of physiological processes, in particular control of the concentration of glucose in blood. http://purl.obolibrary.org/obo/GO_0035935 androgen secretion http://purl.obolibrary.org/obo/GO_0035929 steroid hormone secretion The regulated release of an androgen into the circulatory system. Androgens are steroid hormones that stimulate or control the development and maintenance of masculine characteristics in vertebrates. http://purl.obolibrary.org/obo/GO_0035936 testosterone secretion http://purl.obolibrary.org/obo/GO_0140353 lipid export from cell The regulated release of testosterone into the circulatory system. Testosterone is an androgen having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-4-C-5. http://purl.obolibrary.org/obo/GO_0035938 estradiol secretion http://purl.obolibrary.org/obo/GO_0035929 steroid hormone secretion The regulated release of estradiol into the circulatory system. http://purl.obolibrary.org/obo/GO_0035981 tongue muscle cell differentiation http://purl.obolibrary.org/obo/GO_0098528 skeletal muscle fiber differentiation The process in which a relatively unspecialized cell acquires specialized features of a tongue muscle cell. http://purl.obolibrary.org/obo/GO_0035990 tendon cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a tendon cell. Tendon cell are elongated fibrocytes in which the cytoplasm is stretched between the collagen fibres of the tendon. Tendon cells have a central cell nucleus with a prominent nucleolus, a well-developed rough endoplasmic reticulum, and are responsible for synthesis and turnover of tendon fibres and ground substance. http://purl.obolibrary.org/obo/GO_0035992 tendon formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process that gives rise to a tendon. This process pertains to the initial formation of a tendon from unspecified parts. http://purl.obolibrary.org/obo/GO_0035993 deltoid tuberosity development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the deltoid tuberosity over time, from its formation to the mature structure. The deltoid tuberosity is the region on the shaft of the humerus to which the deltoid muscle attaches. The deltoid tuberosity develops through endochondral ossification in a two-phase process; an initiating tendon-dependent phase, and a muscle-dependent growth phase. http://purl.obolibrary.org/obo/GO_0036022 limb joint morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structures of a limb joint are generated and organized. A limb joint is a flexible region that separates the rigid sections of a limb to allow movement in a controlled manner. http://purl.obolibrary.org/obo/GO_0036035 osteoclast development http://purl.obolibrary.org/obo/GO_0061515 myeloid cell development The process whose specific outcome is the progression of a osteoclast from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue. http://purl.obolibrary.org/obo/GO_0036037 CD8-positive, alpha-beta T cell activation http://purl.obolibrary.org/obo/GO_0046631 alpha-beta T cell activation The change in morphology and behavior of a CD8-positive, alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. http://purl.obolibrary.org/obo/GO_0036053 glomerular endothelium fenestra http://purl.obolibrary.org/obo/GO_0046930 pore complex A large plasma membrane-lined circular pore that perforates the flattened glomerular endothelium and, unlike those of other fenestrated capillaries, is not spanned by diaphragms; the density and size of glomerular fenestrae account, at least in part, for the high permeability of the glomerular capillary wall to water and small solutes. http://purl.obolibrary.org/obo/GO_0036098 male germ-line stem cell population maintenance http://purl.obolibrary.org/obo/GO_0030718 germ-line stem cell population maintenance The process by which an organism or tissue maintains a population of male germ-line stem cells. http://purl.obolibrary.org/obo/GO_0036099 female germ-line stem cell population maintenance http://purl.obolibrary.org/obo/GO_0030718 germ-line stem cell population maintenance The process by which an organism or tissue maintains a population of female germ-line stem cells. http://purl.obolibrary.org/obo/GO_0036135 Schwann cell migration http://purl.obolibrary.org/obo/GO_0008347 glial cell migration The orderly movement of a Schwann cell from one site to another. A Schwann cell is a glial cell that ensheathes axons of neuron in the peripheral nervous system and is necessary for their maintenance and function. http://purl.obolibrary.org/obo/GO_0036145 dendritic cell homeostasis http://purl.obolibrary.org/obo/GO_0001776 leukocyte homeostasis The process of regulating the proliferation and elimination of dendritic cells such that the total number of dendritic cells within a whole or part of an organism is stable over time in the absence of an outside stimulus. http://purl.obolibrary.org/obo/GO_0036156 inner dynein arm http://purl.obolibrary.org/obo/GO_0005858 axonemal dynein complex Inner arm structure present on the outer doublet microtubules of ciliary and flagellar axonemes. The structure of inner dynein arms is complex and may vary within the axoneme. Inner dynein arms are heteromeric, comprising 8 different heavy chains and various subunits. Inner and outer dynein arms have different functions in the generation of microtubule-based motility. http://purl.obolibrary.org/obo/GO_0036157 outer dynein arm http://purl.obolibrary.org/obo/GO_0005858 axonemal dynein complex Outer arm structure present on the outer doublet microtubules of ciliary and flagellar axonemes. Outer dynein arms contain 2-3 heavy chains, two or more intermediate chains and a cluster of 4-8 light chains. Inner and outer dynein arms have different functions in the generation of microtubule-based motility. http://purl.obolibrary.org/obo/GO_0036158 outer dynein arm assembly http://purl.obolibrary.org/obo/GO_0070286 axonemal dynein complex assembly The aggregation, arrangement and bonding together of a set of components to form an axonemal dynein outer arm, an outer arm structure present on the outer doublet microtubules of ciliary and flagellar axonemes. http://purl.obolibrary.org/obo/GO_0036159 inner dynein arm assembly http://purl.obolibrary.org/obo/GO_0070286 axonemal dynein complex assembly The aggregation, arrangement and bonding together of a set of components to form an axonemal dynein inner arm, an inner arm structure present on the outer doublet microtubules of ciliary and flagellar axonemes. http://purl.obolibrary.org/obo/GO_0036160 melanocyte-stimulating hormone secretion http://purl.obolibrary.org/obo/GO_0030072 peptide hormone secretion The regulated release of a melanocyte-stimulating hormone, any of a group of peptide hormones that are produced by cells in the intermediate lobe of the pituitary gland, and stimulate the production of melanin to increase pigmentation. http://purl.obolibrary.org/obo/GO_0036161 calcitonin secretion http://purl.obolibrary.org/obo/GO_0030072 peptide hormone secretion The regulated release of calcitonin, a peptide hormone that participates in calcium and phosphorus metabolism, from a cell. http://purl.obolibrary.org/obo/GO_0036162 oxytocin production http://purl.obolibrary.org/obo/GO_0010467 gene expression The appearance of oxytocin, a cyclic nonapeptide hormone with amino acid sequence CYIQNCPLG, due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Oxytocin is the principal uterine-contracting and milk-ejecting hormone of the posterior pituitary, and together with the neuropeptide vasopressin, is believed to influence social cognition and behavior. It also acts as a neurotransmitter in the brain. http://purl.obolibrary.org/obo/GO_0036179 osteoclast maturation http://purl.obolibrary.org/obo/GO_0048469 cell maturation A developmental process, independent of morphogenetic (shape) change, that is required for an osteoclast cell to attain its fully functional state. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue, and which typically differentiates from monocytes. http://purl.obolibrary.org/obo/GO_0036194 muscle cell projection http://purl.obolibrary.org/obo/GO_0120025 plasma membrane bounded cell projection A prolongation or process extending from a muscle cell. A muscle cell is a mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns. http://purl.obolibrary.org/obo/GO_0036195 muscle cell projection membrane http://purl.obolibrary.org/obo/GO_0031253 cell projection membrane The portion of the plasma membrane surrounding a muscle cell projection. http://purl.obolibrary.org/obo/GO_0036230 granulocyte activation http://purl.obolibrary.org/obo/GO_0002274 myeloid leukocyte activation The change in morphology and behavior of a granulocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. http://purl.obolibrary.org/obo/GO_0036304 umbilical cord morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structures of the umbilical cord are generated and organized. The umbilical cord is an organ or embryonic origin consisting of the 2 umbilical arteries and the one umbilical vein. The umbilical cord connects the cardiovascular system of the fetus to the mother via the placenta. http://purl.obolibrary.org/obo/GO_0036305 ameloblast differentiation http://purl.obolibrary.org/obo/GO_0002065 columnar/cuboidal epithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of an ameloblast, a cylindrical epithelial cell in the innermost layer of the enamel organ. http://purl.obolibrary.org/obo/GO_0036321 ghrelin secretion http://purl.obolibrary.org/obo/GO_0030072 peptide hormone secretion The regulated release of ghrelin from a cell. Ghrelin is a 28 amino acid hunger-stimulating peptide hormone. http://purl.obolibrary.org/obo/GO_0036322 pancreatic polypeptide secretion http://purl.obolibrary.org/obo/GO_0030072 peptide hormone secretion The regulated release of pancreatic polypeptide (PP) from a cell. Pancreatic polypeptide is a 36 amino acid polypeptide secreted by islets of Langerhans cells in the pancreas. http://purl.obolibrary.org/obo/GO_0036333 hepatocyte homeostasis http://purl.obolibrary.org/obo/GO_0048872 homeostasis of number of cells Any biological process involved in the maintenance of the steady-state number of hepatocytes within a population of cells. Hepatocytes are specialized epithelial cells of the liver that are organized into interconnected plates called lobules. http://purl.obolibrary.org/obo/GO_0036334 epidermal stem cell homeostasis http://purl.obolibrary.org/obo/GO_0048872 homeostasis of number of cells Any biological process involved in the maintenance of the steady-state number of epidermal stem cells within a population of cells. http://purl.obolibrary.org/obo/GO_0036342 post-anal tail morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which a post-anal tail is generated and organized. A post-anal tail is a muscular region of the body that extends posterior to the anus. The post-anal tail may aid locomotion and balance. http://purl.obolibrary.org/obo/GO_0036345 platelet maturation http://purl.obolibrary.org/obo/GO_0048469 cell maturation A developmental process, independent of morphogenetic (shape) change, that is required for a platelet to attain its fully functional state. A platelet is a non-nucleated disk-shaped cell formed by extrusion from megakaryocytes, found in the blood of all mammals, and mainly involved in blood coagulation. http://purl.obolibrary.org/obo/GO_0036376 sodium ion export across plasma membrane http://purl.obolibrary.org/obo/GO_0140115 export across plasma membrane The directed movement of sodium ions from inside of a cell, across the plasma membrane and into the extracellular region. http://purl.obolibrary.org/obo/GO_0036444 calcium import into the mitochondrion http://purl.obolibrary.org/obo/GO_0006851 mitochondrial calcium ion transmembrane transport A process in which a calcium ion (Ca2+) is transported from the cytosol into the mitochondrial matrix. http://purl.obolibrary.org/obo/GO_0036446 myofibroblast differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which an undifferentiated cell acquires the features of a myofibroblast cell. http://purl.obolibrary.org/obo/GO_0036457 keratohyalin granule http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure A cytoplasmic, non-membrane bound granule of, at least, keratinocyte. Associated to keratin intermediate filaments and partially crosslinked to the cell envelope. http://purl.obolibrary.org/obo/GO_0036484 trunk neural crest cell migration http://purl.obolibrary.org/obo/GO_0001755 neural crest cell migration The characteristic movement of trunk neural crest cells from the neural tube to other locations in the vertebrate embryo. http://purl.obolibrary.org/obo/GO_0036504 Golgi membrane fusion http://purl.obolibrary.org/obo/GO_0090174 organelle membrane fusion The joining of two lipid bilayers that surround the Golgi apparatus to form a single Golgi membrane. http://purl.obolibrary.org/obo/GO_0036520 astrocyte-dopaminergic neuron signaling http://purl.obolibrary.org/obo/GO_0150098 glial cell-neuron signaling Cell-cell signaling that mediates the transfer of information from an astrocyte to a dopaminergic neuron. http://purl.obolibrary.org/obo/GO_0038169 somatostatin receptor signaling pathway http://purl.obolibrary.org/obo/GO_0007186 G protein-coupled receptor signaling pathway A G protein-coupled receptor signaling pathway initiated by somatostatin binding to the somatostatin receptor (SSTR) on the surface of a target cell, and ending with the regulation of a downstream cellular process. http://purl.obolibrary.org/obo/GO_0039006 pronephric nephron tubule formation http://purl.obolibrary.org/obo/GO_0072079 nephron tubule formation The developmental process pertaining to the initial formation of a pronephric nephron tubule from unspecified parts. A pronephric nephron tubule is an epithelial tube that is part of a nephron in the pronephros. http://purl.obolibrary.org/obo/GO_0039007 pronephric nephron morphogenesis http://purl.obolibrary.org/obo/GO_0072028 nephron morphogenesis The process in which the anatomical structures of the pronephric nephron are generated and organized. A pronephric nephron is the functional unit of the pronephros. http://purl.obolibrary.org/obo/GO_0039008 pronephric nephron tubule morphogenesis http://purl.obolibrary.org/obo/GO_0072078 nephron tubule morphogenesis The process in which the anatomical structures of a pronephric nephron tubule are generated and organized from an epithelium. A pronephric nephron tubule is an epithelial tube that is part of the pronephric nephron. http://purl.obolibrary.org/obo/GO_0039011 pronephric proximal tubule morphogenesis http://purl.obolibrary.org/obo/GO_0072158 proximal tubule morphogenesis The process in which the anatomical structures of a pronephric nephron proximal tubule are generated and organized. A pronephric nephron tubule is an epithelial tube that is part of the pronephros. http://purl.obolibrary.org/obo/GO_0039013 pronephric distal tubule morphogenesis http://purl.obolibrary.org/obo/GO_0072156 distal tubule morphogenesis The process in which the anatomical structures of a pronephric nephron distal tubule are generated and organized. A pronephric nephron tubule is an epithelial tube that is part of the pronephros. http://purl.obolibrary.org/obo/GO_0039015 cell proliferation involved in pronephros development http://purl.obolibrary.org/obo/GO_0072111 cell proliferation involved in kidney development The multiplication or reproduction of cells, resulting in the expansion of the population in the pronephros. http://purl.obolibrary.org/obo/GO_0039019 pronephric nephron development http://purl.obolibrary.org/obo/GO_0072006 nephron development The process whose specific outcome is the progression of the pronephric nephron over time, from its formation to the mature structure. A pronephric nephron is the functional unit of the pronephros. http://purl.obolibrary.org/obo/GO_0039020 pronephric nephron tubule development http://purl.obolibrary.org/obo/GO_0072080 nephron tubule development The process whose specific outcome is the progression of a pronephric nephron tubule over time, from its formation to the mature structure. The pronephric nephron tubule is an epithelial tube that is part of the pronephric nephron and connects the filtration unit (glomerulus or glomus) of the pronephros to the pronephric duct. http://purl.obolibrary.org/obo/GO_0039021 pronephric glomerulus development http://purl.obolibrary.org/obo/GO_0032835 glomerulus development The progression of the glomerulus of the pronephric kidney over time from its initial formation until its mature state. The pronephric glomerulus is part of the pronephric nephron and is restricted to one body segment. http://purl.obolibrary.org/obo/GO_0039022 pronephric duct development http://purl.obolibrary.org/obo/GO_0072176 nephric duct development The process whose specific outcome is the progression of the pronephric duct over time, from its formation to the mature structure. The pronephric duct collects the filtrate from the pronephric tubules and opens to the exterior of the pronephric kidney. http://purl.obolibrary.org/obo/GO_0039023 pronephric duct morphogenesis http://purl.obolibrary.org/obo/GO_0072178 nephric duct morphogenesis The process in which the anatomical structures of the pronephric duct are generated and organized. The pronephric duct collects the filtrate from the pronephric tubules and opens to the exterior of the kidney. http://purl.obolibrary.org/obo/GO_0040012 regulation of locomotion http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process Any process that modulates the frequency, rate or extent of locomotion of a cell or organism. http://purl.obolibrary.org/obo/GO_0040013 negative regulation of locomotion http://purl.obolibrary.org/obo/GO_0040012 regulation of locomotion Any process that stops, prevents, or reduces the frequency, rate or extent of locomotion of a cell or organism. http://purl.obolibrary.org/obo/GO_0040014 regulation of multicellular organism growth http://purl.obolibrary.org/obo/GO_0048638 regulation of developmental growth Any process that modulates the frequency, rate or extent of growth of the body of an organism so that it reaches its usual body size. http://purl.obolibrary.org/obo/GO_0040015 negative regulation of multicellular organism growth http://purl.obolibrary.org/obo/GO_0040014 regulation of multicellular organism growth Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organism to reach its usual body size. http://purl.obolibrary.org/obo/GO_0040016 embryonic cleavage http://purl.obolibrary.org/obo/GO_0051301 cell division The first few specialized divisions of an activated animal egg. http://purl.obolibrary.org/obo/GO_0040017 positive regulation of locomotion http://purl.obolibrary.org/obo/GO_0040012 regulation of locomotion Any process that activates or increases the frequency, rate or extent of locomotion of a cell or organism. http://purl.obolibrary.org/obo/GO_0040018 positive regulation of multicellular organism growth http://purl.obolibrary.org/obo/GO_0048639 positive regulation of developmental growth Any process that activates or increases the frequency, rate or extent of growth of an organism to reach its usual body size. http://purl.obolibrary.org/obo/GO_0040019 positive regulation of embryonic development http://purl.obolibrary.org/obo/GO_0051240 positive regulation of multicellular organismal process Any process that activates or increases the frequency, rate or extent of embryonic development. http://purl.obolibrary.org/obo/GO_0040034 regulation of development, heterochronic http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the consistent predetermined time point at which an integrated living unit or organism progresses from an initial condition to a later condition and the rate at which this time point is reached. http://purl.obolibrary.org/obo/GO_0042045 epithelial fluid transport http://purl.obolibrary.org/obo/GO_0070633 transepithelial transport The directed movement of fluid across epithelia. http://purl.obolibrary.org/obo/GO_0042051 compound eye photoreceptor development http://purl.obolibrary.org/obo/GO_0042462 eye photoreceptor cell development The process whose specific outcome is the progression of a light-responsive receptor in the compound eye over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0042053 regulation of dopamine metabolic process http://purl.obolibrary.org/obo/GO_0042069 regulation of catecholamine metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving dopamine. http://purl.obolibrary.org/obo/GO_0042065 glial cell growth http://purl.obolibrary.org/obo/GO_0048588 developmental cell growth Growth of glial cells, non-neuronal cells that provide support and nutrition, maintain homeostasis, form myelin, and participate in signal transmission in the nervous system. http://purl.obolibrary.org/obo/GO_0042069 regulation of catecholamine metabolic process http://purl.obolibrary.org/obo/GO_0080090 regulation of primary metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving catecholamines. http://purl.obolibrary.org/obo/GO_0042073 intraciliary transport http://purl.obolibrary.org/obo/GO_0010970 transport along microtubule The bidirectional movement of large protein complexes along microtubules within a cilium, mediated by motor proteins. http://purl.obolibrary.org/obo/GO_0042078 germ-line stem cell division http://purl.obolibrary.org/obo/GO_0017145 stem cell division The self-renewing division of a germline stem cell to produce a daughter stem cell and a daughter germ cell, which will divide to form the gametes. http://purl.obolibrary.org/obo/GO_0042101 T cell receptor complex http://purl.obolibrary.org/obo/GO_0098802 plasma membrane signaling receptor complex A protein complex that contains a disulfide-linked heterodimer of T cell receptor (TCR) chains, which are members of the immunoglobulin superfamily, and mediates antigen recognition, ultimately resulting in T cell activation. The TCR heterodimer is associated with the CD3 complex, which consists of the nonpolymorphic polypeptides gamma, delta, epsilon, zeta, and, in some cases, eta (an RNA splice variant of zeta) or Fc epsilon chains. http://purl.obolibrary.org/obo/GO_0042103 positive regulation of T cell homeostatic proliferation http://purl.obolibrary.org/obo/GO_0046013 regulation of T cell homeostatic proliferation Any process that activates or increases the rate or extent of resting T cell proliferation. http://purl.obolibrary.org/obo/GO_0042105 alpha-beta T cell receptor complex http://purl.obolibrary.org/obo/GO_0042101 T cell receptor complex A T cell receptor complex in which the TCR heterodimer comprises alpha and beta chains, associated with the CD3 complex; recognizes a complex consisting of an antigen-derived peptide bound to a class I or class II MHC protein. http://purl.obolibrary.org/obo/GO_0042106 gamma-delta T cell receptor complex http://purl.obolibrary.org/obo/GO_0042101 T cell receptor complex A T cell receptor complex in which the TCR heterodimer comprises gamma and delta chains, associated with the CD3 complex; recognizes antigen directly, without a requirement for processing and presentation by an MHC protein. http://purl.obolibrary.org/obo/GO_0042151 nematocyst http://purl.obolibrary.org/obo/GO_0043232 intracellular membraneless organelle An organelle found in cnidoblast (nematoblast) cells. When matured, these stinging organelles store toxins and can deliver them when the cnidocil (a short extension of the cnidocyst) is stimulated by a prey or another stimulus. http://purl.obolibrary.org/obo/GO_0042157 lipoprotein metabolic process http://purl.obolibrary.org/obo/GO_0019538 protein metabolic process The chemical reactions and pathways involving any conjugated, water-soluble protein in which the covalently attached nonprotein group consists of a lipid or lipids. http://purl.obolibrary.org/obo/GO_0042173 regulation of sporulation resulting in formation of a cellular spore http://purl.obolibrary.org/obo/GO_0043937 regulation of sporulation Any process that modulates the frequency, rate or extent of spore formation. http://purl.obolibrary.org/obo/GO_0042174 negative regulation of sporulation resulting in formation of a cellular spore http://purl.obolibrary.org/obo/GO_0043939 negative regulation of sporulation Any process that stops, prevents, or reduces the frequency, rate or extent of sporulation. http://purl.obolibrary.org/obo/GO_0042176 regulation of protein catabolic process http://purl.obolibrary.org/obo/GO_0009894 regulation of catabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds. http://purl.obolibrary.org/obo/GO_0042177 negative regulation of protein catabolic process http://purl.obolibrary.org/obo/GO_0009895 negative regulation of catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of protein catabolic process. http://purl.obolibrary.org/obo/GO_0042301 phosphate ion binding http://purl.obolibrary.org/obo/GO_0043168 anion binding Binding to a phosphate ion. http://purl.obolibrary.org/obo/GO_0042304 regulation of fatty acid biosynthetic process http://purl.obolibrary.org/obo/GO_0046890 regulation of lipid biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. http://purl.obolibrary.org/obo/GO_0042387 plasmatocyte differentiation http://purl.obolibrary.org/obo/GO_0042386 hemocyte differentiation The process in which a hemocyte precursor cell acquires the characteristics of the phagocytic blood-cell type, the plasmatocyte. Plasmatocytes are a class of arthropod hemocytes important in the cellular defense response. http://purl.obolibrary.org/obo/GO_0042414 epinephrine metabolic process http://purl.obolibrary.org/obo/GO_0006584 catecholamine metabolic process The chemical reactions and pathways involving epinephrine, a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine. http://purl.obolibrary.org/obo/GO_0042415 norepinephrine metabolic process http://purl.obolibrary.org/obo/GO_0006584 catecholamine metabolic process The chemical reactions and pathways involving norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine. http://purl.obolibrary.org/obo/GO_0042417 dopamine metabolic process http://purl.obolibrary.org/obo/GO_0006584 catecholamine metabolic process The chemical reactions and pathways involving dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline. http://purl.obolibrary.org/obo/GO_0042418 epinephrine biosynthetic process http://purl.obolibrary.org/obo/GO_0042423 catecholamine biosynthetic process The chemical reactions and pathways resulting in the formation of epinephrine, a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine. http://purl.obolibrary.org/obo/GO_0042420 dopamine catabolic process http://purl.obolibrary.org/obo/GO_0042424 catecholamine catabolic process The chemical reactions and pathways resulting in the breakdown of dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline. http://purl.obolibrary.org/obo/GO_0042421 norepinephrine biosynthetic process http://purl.obolibrary.org/obo/GO_0042423 catecholamine biosynthetic process The chemical reactions and pathways resulting in the formation of norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine. http://purl.obolibrary.org/obo/GO_0042422 norepinephrine catabolic process http://purl.obolibrary.org/obo/GO_0042424 catecholamine catabolic process The chemical reactions and pathways resulting in the breakdown of norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine. http://purl.obolibrary.org/obo/GO_0042423 catecholamine biosynthetic process http://purl.obolibrary.org/obo/GO_0009713 catechol-containing compound biosynthetic process The chemical reactions and pathways resulting in the formation of any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine. http://purl.obolibrary.org/obo/GO_0042424 catecholamine catabolic process http://purl.obolibrary.org/obo/GO_0019614 catechol-containing compound catabolic process The chemical reactions and pathways resulting in the breakdown of any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine. http://purl.obolibrary.org/obo/GO_0042428 serotonin metabolic process http://purl.obolibrary.org/obo/GO_0042430 indole-containing compound metabolic process The chemical reactions and pathways involving serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties. http://purl.obolibrary.org/obo/GO_0042429 serotonin catabolic process http://purl.obolibrary.org/obo/GO_0042436 indole-containing compound catabolic process The chemical reactions and pathways resulting in the breakdown of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties. http://purl.obolibrary.org/obo/GO_0042436 indole-containing compound catabolic process http://purl.obolibrary.org/obo/GO_0009056 catabolic process The chemical reactions and pathways resulting in the breakdown of compounds that contain an indole (2,3-benzopyrrole) skeleton. http://purl.obolibrary.org/obo/GO_0042442 melatonin catabolic process http://purl.obolibrary.org/obo/GO_0042436 indole-containing compound catabolic process The chemical reactions and pathways resulting in the breakdown of melatonin (N-acetyl-5-methoxytryptamine). http://purl.obolibrary.org/obo/GO_0042462 eye photoreceptor cell development http://purl.obolibrary.org/obo/GO_0042461 photoreceptor cell development Development of a photoreceptor, a sensory cell in the eye that reacts to the presence of light. They usually contain a pigment that undergoes a chemical change when light is absorbed, thus stimulating a nerve. http://purl.obolibrary.org/obo/GO_0042471 ear morphogenesis http://purl.obolibrary.org/obo/GO_0090596 sensory organ morphogenesis The process in which the anatomical structures of the ear are generated and organized. The ear is the sense organ in vertebrates that is specialized for the detection of sound, and the maintenance of balance. Includes the outer ear and middle ear, which collect and transmit sound waves; and the inner ear, which contains the organs of balance and (except in fish) hearing. Also includes the pinna, the visible part of the outer ear, present in some mammals. http://purl.obolibrary.org/obo/GO_0042473 outer ear morphogenesis http://purl.obolibrary.org/obo/GO_0048598 embryonic morphogenesis The process in which the anatomical structures of the outer ear are generated and organized. The outer ear is the part of the ear external to the tympanum (eardrum). It consists of a tube (the external auditory meatus) that directs sound waves on to the tympanum, and may also include the external pinna, which extends beyond the skull. http://purl.obolibrary.org/obo/GO_0042474 middle ear morphogenesis http://purl.obolibrary.org/obo/GO_0048598 embryonic morphogenesis The process in which the anatomical structures of the middle ear are generated and organized. The middle ear is the air-filled cavity within the skull of vertebrates that lies between the outer ear and the inner ear. It is linked to the pharynx (and therefore to outside air) via the Eustachian tube and in mammals contains the three ear ossicles, which transmit auditory vibrations from the outer ear (via the tympanum) to the inner ear (via the oval window). http://purl.obolibrary.org/obo/GO_0042475 odontogenesis of dentin-containing tooth http://purl.obolibrary.org/obo/GO_0042476 odontogenesis The process whose specific outcome is the progression of a dentin-containing tooth over time, from its formation to the mature structure. A dentin-containing tooth is a hard, bony organ borne on the jaw or other bone of a vertebrate, and is composed mainly of dentin, a dense calcified substance, covered by a layer of enamel. http://purl.obolibrary.org/obo/GO_0042476 odontogenesis http://purl.obolibrary.org/obo/GO_0009887 animal organ morphogenesis The process whose specific outcome is the progression of a tooth or teeth over time, from formation to the mature structure(s). A tooth is any hard bony, calcareous, or chitinous organ found in the mouth or pharynx of an animal and used in procuring or masticating food. http://purl.obolibrary.org/obo/GO_0042478 regulation of eye photoreceptor cell development http://purl.obolibrary.org/obo/GO_0060284 regulation of cell development Any process that modulates the frequency, rate or extent of eye photoreceptor development. http://purl.obolibrary.org/obo/GO_0042479 positive regulation of eye photoreceptor cell development http://purl.obolibrary.org/obo/GO_0010720 positive regulation of cell development Any process that activates or increases the frequency, rate or extent of eye photoreceptor development. http://purl.obolibrary.org/obo/GO_0042480 negative regulation of eye photoreceptor cell development http://purl.obolibrary.org/obo/GO_0010721 negative regulation of cell development Any process that stops, prevents, or reduces the frequency, rate or extent of eye photoreceptor development. http://purl.obolibrary.org/obo/GO_0042481 regulation of odontogenesis http://purl.obolibrary.org/obo/GO_2000027 regulation of animal organ morphogenesis Any process that modulates the frequency, rate or extent of the formation and development of a tooth or teeth. http://purl.obolibrary.org/obo/GO_0042482 positive regulation of odontogenesis http://purl.obolibrary.org/obo/GO_0042481 regulation of odontogenesis Any process that activates or increases the frequency, rate or extent of the formation and development of a tooth or teeth. http://purl.obolibrary.org/obo/GO_0042483 negative regulation of odontogenesis http://purl.obolibrary.org/obo/GO_0042481 regulation of odontogenesis Any process that stops, prevents, or reduces the frequency, rate or extent of the formation and development of a tooth or teeth. http://purl.obolibrary.org/obo/GO_0042487 regulation of odontogenesis of dentin-containing tooth http://purl.obolibrary.org/obo/GO_0042481 regulation of odontogenesis Any process that modulates the frequency, rate or extent of the formation and development of teeth, the hard, bony appendages which are borne on the jaws, or on other bones in the walls of the mouth or pharynx of most vertebrates. http://purl.obolibrary.org/obo/GO_0042488 positive regulation of odontogenesis of dentin-containing tooth http://purl.obolibrary.org/obo/GO_0042487 regulation of odontogenesis of dentin-containing tooth Any process that activates or increases the frequency, rate or extent of the formation and development of teeth, the hard, bony appendages that are borne on the jaws, or on other bones in the walls of the mouth or pharynx of most vertebrates. http://purl.obolibrary.org/obo/GO_0042489 negative regulation of odontogenesis of dentin-containing tooth http://purl.obolibrary.org/obo/GO_0042487 regulation of odontogenesis of dentin-containing tooth Any process that stops, prevents, or reduces the frequency, rate or extent of the formation and development of teeth, the hard, bony appendages which are borne on the jaws, or on other bones in the walls of the mouth or pharynx. http://purl.obolibrary.org/obo/GO_0042490 mechanoreceptor differentiation http://purl.obolibrary.org/obo/GO_0030182 neuron differentiation The process in which a relatively unspecialized cell acquires specialized features of a mechanoreceptor, a cell specialized to transduce mechanical stimuli and relay that information centrally in the nervous system. http://purl.obolibrary.org/obo/GO_0042571 immunoglobulin complex, circulating http://purl.obolibrary.org/obo/GO_0019814 immunoglobulin complex An immunoglobulin complex that is secreted into extracellular space and found in mucosal areas or other tissues or circulating in the blood or lymph. In its canonical form, a circulating immunoglobulin complex is composed of two identical heavy chains and two identical light chains, held together by disulfide bonds. Some forms of are polymers of the basic structure and contain additional components such as J-chain and the secretory component. http://purl.obolibrary.org/obo/GO_0042582 azurophil granule http://purl.obolibrary.org/obo/GO_0030141 secretory granule Primary lysosomal granule readily stainable with a Romanowsky stain. http://purl.obolibrary.org/obo/GO_0042585 germinal vesicle http://purl.obolibrary.org/obo/GO_0001674 female germ cell nucleus The enlarged, fluid filled nucleus of a primary oocyte, the development of which is suspended in prophase I of the first meiotic division between embryohood and sexual maturity. http://purl.obolibrary.org/obo/GO_0042588 zymogen granule http://purl.obolibrary.org/obo/GO_0030141 secretory granule A membrane-bounded, cytoplasmic secretory granule found in enzyme-secreting cells and visible by light microscopy. Contain zymogen, an inactive enzyme precursor, often of a digestive enzyme. http://purl.obolibrary.org/obo/GO_0042589 zymogen granule membrane http://purl.obolibrary.org/obo/GO_0030667 secretory granule membrane The lipid bilayer surrounding a zymogen granule. http://purl.obolibrary.org/obo/GO_0042599 lamellar body http://purl.obolibrary.org/obo/GO_0030141 secretory granule A membrane-bounded organelle, specialized for the storage and secretion of various substances (surfactant phospholipids, glycoproteins and acid phosphates) which are arranged in the form of tightly packed, concentric, membrane sheets or lamellae. Has some similar properties to, but is distinct from, a lysosome. http://purl.obolibrary.org/obo/GO_0042608 T cell receptor binding http://purl.obolibrary.org/obo/GO_0044877 protein-containing complex binding Binding to a T cell receptor, the antigen-recognizing receptor on the surface of T cells. http://purl.obolibrary.org/obo/GO_0042613 MHC class II protein complex http://purl.obolibrary.org/obo/GO_0042611 MHC protein complex A transmembrane protein complex composed of an MHC class II alpha and MHC class II beta chain, and with or without a bound peptide or polysaccharide antigen. http://purl.obolibrary.org/obo/GO_0042629 mast cell granule http://purl.obolibrary.org/obo/GO_0005764 lysosome Coarse, bluish-black staining cytoplasmic granules, bounded by a plasma membrane and found in mast cells and basophils. Contents include histamine, heparin, chondroitin sulfates, chymase and tryptase. http://purl.obolibrary.org/obo/GO_0042634 regulation of hair cycle http://purl.obolibrary.org/obo/GO_0051239 regulation of multicellular organismal process Any process that modulates the frequency, rate or extent of the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair. http://purl.obolibrary.org/obo/GO_0042635 positive regulation of hair cycle http://purl.obolibrary.org/obo/GO_0042634 regulation of hair cycle Any process that activates or increases the frequency, rate or extent of the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair. http://purl.obolibrary.org/obo/GO_0042636 negative regulation of hair cycle http://purl.obolibrary.org/obo/GO_0042634 regulation of hair cycle Any process that stops, prevents, or reduces the frequency, rate or extent of the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair. http://purl.obolibrary.org/obo/GO_0042644 chloroplast nucleoid http://purl.obolibrary.org/obo/GO_0042646 plastid nucleoid The region of a chloroplast to which the DNA is confined. http://purl.obolibrary.org/obo/GO_0042648 chloroplast chromosome http://purl.obolibrary.org/obo/GO_0009508 plastid chromosome A circular DNA molecule containing chloroplast encoded genes. http://purl.obolibrary.org/obo/GO_0042670 retinal cone cell differentiation http://purl.obolibrary.org/obo/GO_0060219 camera-type eye photoreceptor cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a retinal cone cell. http://purl.obolibrary.org/obo/GO_0042675 compound eye cone cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a compound eye cone cell, a cone-shaped cell, that focuses light in a compound eye. http://purl.obolibrary.org/obo/GO_0042688 crystal cell differentiation http://purl.obolibrary.org/obo/GO_0042386 hemocyte differentiation The process in which a hemocyte precursor cell acquires the characteristics of a crystal cell, a class of cells that contain crystalline inclusions and are involved in the melanization of pathogenic material in the hemolymph. http://purl.obolibrary.org/obo/GO_0042689 regulation of crystal cell differentiation http://purl.obolibrary.org/obo/GO_0045610 regulation of hemocyte differentiation Any process that modulates the frequency, rate or extent of crystal cell differentiation. http://purl.obolibrary.org/obo/GO_0042690 negative regulation of crystal cell differentiation http://purl.obolibrary.org/obo/GO_0045611 negative regulation of hemocyte differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of crystal cell differentiation. http://purl.obolibrary.org/obo/GO_0042691 positive regulation of crystal cell differentiation http://purl.obolibrary.org/obo/GO_0045612 positive regulation of hemocyte differentiation Any process that activates or increases the frequency, rate or extent of crystal cell differentiation. http://purl.obolibrary.org/obo/GO_0042692 muscle cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a muscle cell. http://purl.obolibrary.org/obo/GO_0042701 progesterone secretion http://purl.obolibrary.org/obo/GO_0035929 steroid hormone secretion The regulated release of progesterone, a steroid hormone, by the corpus luteum of the ovary and by the placenta. http://purl.obolibrary.org/obo/GO_0042702 uterine wall growth http://purl.obolibrary.org/obo/GO_0048589 developmental growth The regrowth of the endometrium and blood vessels in the uterus following menstruation, resulting from a rise in progesterone levels. http://purl.obolibrary.org/obo/GO_0042713 sperm ejaculation http://purl.obolibrary.org/obo/GO_0048609 multicellular organismal reproductive process The expulsion of seminal fluid, thick white fluid containing spermatozoa, from the male genital tract. http://purl.obolibrary.org/obo/GO_0042953 lipoprotein transport http://purl.obolibrary.org/obo/GO_0044872 lipoprotein localization The directed movement of any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0042996 regulation of Golgi to plasma membrane protein transport http://purl.obolibrary.org/obo/GO_0060627 regulation of vesicle-mediated transport Any process that modulates the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane. http://purl.obolibrary.org/obo/GO_0042997 negative regulation of Golgi to plasma membrane protein transport http://purl.obolibrary.org/obo/GO_1903077 negative regulation of protein localization to plasma membrane Any process that stops, prevents, or reduces the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane. http://purl.obolibrary.org/obo/GO_0042998 positive regulation of Golgi to plasma membrane protein transport http://purl.obolibrary.org/obo/GO_1903078 positive regulation of protein localization to plasma membrane Any process that activates or increases the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane. http://purl.obolibrary.org/obo/GO_0043001 Golgi to plasma membrane protein transport http://purl.obolibrary.org/obo/GO_0072659 protein localization to plasma membrane The directed movement of proteins from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane. Golgi to plasma membrane transport precedes exocytosis. http://purl.obolibrary.org/obo/GO_0043030 regulation of macrophage activation http://purl.obolibrary.org/obo/GO_0002694 regulation of leukocyte activation Any process that modulates the frequency or rate of macrophage activation. http://purl.obolibrary.org/obo/GO_0043031 negative regulation of macrophage activation http://purl.obolibrary.org/obo/GO_0043030 regulation of macrophage activation Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage activation. http://purl.obolibrary.org/obo/GO_0043032 positive regulation of macrophage activation http://purl.obolibrary.org/obo/GO_0043030 regulation of macrophage activation Any process that stimulates, induces or increases the rate of macrophage activation. http://purl.obolibrary.org/obo/GO_0043038 amino acid activation http://purl.obolibrary.org/obo/GO_0006520 amino acid metabolic process The modification of an amino acid to an active form, for incorporation into a peptide, protein or other macromolecule. http://purl.obolibrary.org/obo/GO_0043049 otic placode formation http://purl.obolibrary.org/obo/GO_0060788 ectodermal placode formation The initial developmental process that will lead to the formation of the vertebrate inner ear. The otic placode forms as a thickening of the head ectoderm adjacent to the developing hindbrain. http://purl.obolibrary.org/obo/GO_0043116 negative regulation of vascular permeability http://purl.obolibrary.org/obo/GO_0043114 regulation of vascular permeability Any process that reduces the extent to which blood vessels can be pervaded by fluid. http://purl.obolibrary.org/obo/GO_0043117 positive regulation of vascular permeability http://purl.obolibrary.org/obo/GO_0043114 regulation of vascular permeability Any process that increases the extent to which blood vessels can be pervaded by fluid. http://purl.obolibrary.org/obo/GO_0043129 surfactant homeostasis http://purl.obolibrary.org/obo/GO_0140962 multicellular organismal-level chemical homeostasis Any process involved in the maintenance of a steady-state level of a surface-active agent that maintains the surface tension of a liquid. http://purl.obolibrary.org/obo/GO_0043133 hindgut contraction http://purl.obolibrary.org/obo/GO_0022600 digestive system process A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the hindgut. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The hindgut is the posterior part of the alimentary canal, including the rectum, and the large intestine. http://purl.obolibrary.org/obo/GO_0043134 regulation of hindgut contraction http://purl.obolibrary.org/obo/GO_0044058 regulation of digestive system process Any process that modulates the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine. http://purl.obolibrary.org/obo/GO_0043143 regulation of translation by machinery localization http://purl.obolibrary.org/obo/GO_0008104 intracellular protein localization Any process in which proteins and protein complexes involved in translation are transported to, or maintained in, a specific location. http://purl.obolibrary.org/obo/GO_0043158 heterocyst development http://purl.obolibrary.org/obo/GO_0048869 cellular developmental process The cellular developmental process by which a cell becomes a heterocyst, a cell that carries out nitrogen fixation. This process involves changes to the cell wall, expression of nitrogenase and other proteins involved in nitrogen fixation, and degradation of photosystem II, which produces oxygen. This process is known to occur in some cyanobacteria. http://purl.obolibrary.org/obo/GO_0043167 ion binding http://purl.obolibrary.org/obo/GO_0036094 small molecule binding Binding to an ion, a charged atoms or groups of atoms. http://purl.obolibrary.org/obo/GO_0043184 vascular endothelial growth factor receptor 2 binding http://purl.obolibrary.org/obo/GO_0005172 vascular endothelial growth factor receptor binding Binding to a vascular endothelial growth factor receptor 2. http://purl.obolibrary.org/obo/GO_0043195 terminal bouton http://purl.obolibrary.org/obo/GO_0098793 presynapse Terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters. The axon terminus is considered to be the whole region of thickening and the terminal bouton is a specialized region of it. http://purl.obolibrary.org/obo/GO_0043208 glycosphingolipid binding http://purl.obolibrary.org/obo/GO_0046625 sphingolipid binding Binding to glycosphingolipid, a compound with residues of sphingoid and at least one monosaccharide. http://purl.obolibrary.org/obo/GO_0043209 myelin sheath http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure An electrically insulating fatty layer that surrounds the axons of many neurons. It is an outgrowth of glial cells: Schwann cells supply the myelin for peripheral neurons while oligodendrocytes supply it to those of the central nervous system. http://purl.obolibrary.org/obo/GO_0043229 intracellular organelle http://purl.obolibrary.org/obo/GO_0043226 organelle Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane. http://purl.obolibrary.org/obo/GO_0043230 extracellular organelle http://purl.obolibrary.org/obo/GO_0043226 organelle Organized structure of distinctive morphology and function, occurring outside the cell. Includes, for example, extracellular membrane vesicles (EMVs) and the cellulosomes of anaerobic bacteria and fungi. http://purl.obolibrary.org/obo/GO_0043242 negative regulation of protein-containing complex disassembly http://purl.obolibrary.org/obo/GO_0051129 negative regulation of cellular component organization Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components. http://purl.obolibrary.org/obo/GO_0043243 positive regulation of protein-containing complex disassembly http://purl.obolibrary.org/obo/GO_0051130 positive regulation of cellular component organization Any process that activates or increases the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components. http://purl.obolibrary.org/obo/GO_0043249 erythrocyte maturation http://purl.obolibrary.org/obo/GO_0048469 cell maturation A developmental process, independent of morphogenetic (shape) change, that is required for an erythrocyte to attain its fully functional state. http://purl.obolibrary.org/obo/GO_0043264 extracellular membraneless organelle http://purl.obolibrary.org/obo/GO_0043228 membraneless organelle Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring outside the cell. http://purl.obolibrary.org/obo/GO_0043266 regulation of potassium ion transport http://purl.obolibrary.org/obo/GO_0010959 regulation of metal ion transport Any process that modulates the frequency, rate or extent of the directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0043267 negative regulation of potassium ion transport http://purl.obolibrary.org/obo/GO_0043271 negative regulation of monoatomic ion transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0043268 positive regulation of potassium ion transport http://purl.obolibrary.org/obo/GO_0043270 positive regulation of monoatomic ion transport Any process that activates or increases the frequency, rate or extent of the directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0043277 apoptotic cell clearance http://purl.obolibrary.org/obo/GO_0006909 phagocytosis The recognition and removal of an apoptotic cell by a neighboring cell or by a phagocyte. http://purl.obolibrary.org/obo/GO_0043282 chordate pharyngeal muscle development http://purl.obolibrary.org/obo/GO_0007517 muscle organ development The process whose specific outcome is the progression of the pharyngeal muscle over time, from its formation to the mature structure. A pharyngeal muscle is any muscle that forms part of the pharynx. http://purl.obolibrary.org/obo/GO_0043300 regulation of leukocyte degranulation http://purl.obolibrary.org/obo/GO_1903305 regulation of regulated secretory pathway Any process that modulates the frequency, rate, or extent of leukocyte degranulation. http://purl.obolibrary.org/obo/GO_0043301 negative regulation of leukocyte degranulation http://purl.obolibrary.org/obo/GO_1903306 negative regulation of regulated secretory pathway Any process that stops, prevents, or reduces the rate of leukocyte degranulation. http://purl.obolibrary.org/obo/GO_0043302 positive regulation of leukocyte degranulation http://purl.obolibrary.org/obo/GO_1903307 positive regulation of regulated secretory pathway Any process that activates or increases the frequency, rate or extent of leukocyte degranulation. http://purl.obolibrary.org/obo/GO_0043304 regulation of mast cell degranulation http://purl.obolibrary.org/obo/GO_0043300 regulation of leukocyte degranulation Any process that modulates the frequency, rate, or extent of mast cell degranulation. http://purl.obolibrary.org/obo/GO_0043305 negative regulation of mast cell degranulation http://purl.obolibrary.org/obo/GO_0043304 regulation of mast cell degranulation Any process that stops, prevents, or reduces the rate of mast cell degranulation. http://purl.obolibrary.org/obo/GO_0043306 positive regulation of mast cell degranulation http://purl.obolibrary.org/obo/GO_0043304 regulation of mast cell degranulation Any process that activates or increases the frequency, rate or extent of mast cell degranulation. http://purl.obolibrary.org/obo/GO_0043308 eosinophil degranulation http://purl.obolibrary.org/obo/GO_0043299 leukocyte degranulation The regulated exocytosis of secretory granules containing preformed mediators such as major basic protein, eosinophil peroxidase, and eosinophil cationic protein by an eosinophil. http://purl.obolibrary.org/obo/GO_0043309 regulation of eosinophil degranulation http://purl.obolibrary.org/obo/GO_0043300 regulation of leukocyte degranulation Any process that modulates the frequency, rate, or extent of eosinophil degranulation. http://purl.obolibrary.org/obo/GO_0043310 negative regulation of eosinophil degranulation http://purl.obolibrary.org/obo/GO_0043309 regulation of eosinophil degranulation Any process that stops, prevents, or reduces the rate of eosinophil degranulation. http://purl.obolibrary.org/obo/GO_0043311 positive regulation of eosinophil degranulation http://purl.obolibrary.org/obo/GO_0043309 regulation of eosinophil degranulation Any process that activates or increases the frequency, rate or extent of eosinophil degranulation. http://purl.obolibrary.org/obo/GO_0043312 neutrophil degranulation http://purl.obolibrary.org/obo/GO_0043299 leukocyte degranulation The regulated exocytosis of secretory granules containing preformed mediators such as proteases, lipases, and inflammatory mediators by a neutrophil. http://purl.obolibrary.org/obo/GO_0043313 regulation of neutrophil degranulation http://purl.obolibrary.org/obo/GO_0043300 regulation of leukocyte degranulation Any process that modulates the frequency, rate, or extent of neutrophil degranulation. http://purl.obolibrary.org/obo/GO_0043314 negative regulation of neutrophil degranulation http://purl.obolibrary.org/obo/GO_0043313 regulation of neutrophil degranulation Any process that stops, prevents, or reduces the rate of neutrophil degranulation. http://purl.obolibrary.org/obo/GO_0043315 positive regulation of neutrophil degranulation http://purl.obolibrary.org/obo/GO_0043313 regulation of neutrophil degranulation Any process that activates or increases the frequency, rate or extent of neutrophil degranulation. http://purl.obolibrary.org/obo/GO_0043316 cytotoxic T cell degranulation http://purl.obolibrary.org/obo/GO_0043299 leukocyte degranulation The regulated exocytosis of secretory granules containing preformed mediators such as perforin and granzymes by a cytotoxic T cell. http://purl.obolibrary.org/obo/GO_0043317 regulation of cytotoxic T cell degranulation http://purl.obolibrary.org/obo/GO_0043300 regulation of leukocyte degranulation Any process that modulates the frequency, rate, or extent of cytotoxic T cell degranulation. http://purl.obolibrary.org/obo/GO_0043318 negative regulation of cytotoxic T cell degranulation http://purl.obolibrary.org/obo/GO_0043317 regulation of cytotoxic T cell degranulation Any process that stops, prevents, or reduces the rate of cytotoxic T cell degranulation. http://purl.obolibrary.org/obo/GO_0043319 positive regulation of cytotoxic T cell degranulation http://purl.obolibrary.org/obo/GO_0043317 regulation of cytotoxic T cell degranulation Any process that activates or increases the frequency, rate or extent of cytotoxic T cell degranulation. http://purl.obolibrary.org/obo/GO_0043320 natural killer cell degranulation http://purl.obolibrary.org/obo/GO_0043299 leukocyte degranulation The regulated exocytosis of secretory granules containing preformed mediators such as perforin and granzymes by a natural killer cell. http://purl.obolibrary.org/obo/GO_0043321 regulation of natural killer cell degranulation http://purl.obolibrary.org/obo/GO_0043300 regulation of leukocyte degranulation Any process that modulates the frequency, rate, or extent of natural killer cell degranulation. http://purl.obolibrary.org/obo/GO_0043322 negative regulation of natural killer cell degranulation http://purl.obolibrary.org/obo/GO_0043321 regulation of natural killer cell degranulation Any process that stops, prevents, or reduces the rate of natural killer cell degranulation. http://purl.obolibrary.org/obo/GO_0043323 positive regulation of natural killer cell degranulation http://purl.obolibrary.org/obo/GO_0043321 regulation of natural killer cell degranulation Any process that activates or increases the frequency, rate or extent of natural killer cell degranulation. http://purl.obolibrary.org/obo/GO_0043324 pigment metabolic process involved in developmental pigmentation http://purl.obolibrary.org/obo/GO_0043474 pigment metabolic process involved in pigmentation The chemical reactions and pathways involving biological pigments e.g. melanin, occurring as part of the development of an organ or organism. http://purl.obolibrary.org/obo/GO_0043353 enucleate erythrocyte differentiation http://purl.obolibrary.org/obo/GO_0030218 erythrocyte differentiation The process in which a myeloid precursor cell acquires specialized features of an erythrocyte without a nucleus. An example of this process is found in Mus musculus. http://purl.obolibrary.org/obo/GO_0043354 enucleate erythrocyte maturation http://purl.obolibrary.org/obo/GO_0043249 erythrocyte maturation A developmental process, independent of morphogenetic (shape) change, that is required for an enucleate erythrocyte to attain its fully functional state. An enucleate erythrocyte is an erythrocyte without a nucleus. http://purl.obolibrary.org/obo/GO_0043362 nucleate erythrocyte maturation http://purl.obolibrary.org/obo/GO_0043249 erythrocyte maturation A developmental process, independent of morphogenetic (shape) change, that is required for a nucleate erythrocyte to attain its fully functional state. A nucleate erythrocyte is an erythrocyte with a nucleus. http://purl.obolibrary.org/obo/GO_0043363 nucleate erythrocyte differentiation http://purl.obolibrary.org/obo/GO_0030218 erythrocyte differentiation The process in which a myeloid precursor cell acquires specializes features of an erythrocyte with a nucleus, as found in non-mammalian vertebrates such as birds. http://purl.obolibrary.org/obo/GO_0043368 positive T cell selection http://purl.obolibrary.org/obo/GO_0045058 T cell selection The process of sparing immature T cells which react with self-MHC protein complexes with low affinity levels from apoptotic death. http://purl.obolibrary.org/obo/GO_0043376 regulation of CD8-positive, alpha-beta T cell differentiation http://purl.obolibrary.org/obo/GO_2001185 regulation of CD8-positive, alpha-beta T cell activation Any process that modulates the frequency, rate, or extent of CD8-positive, alpha-beta T cell differentiation. http://purl.obolibrary.org/obo/GO_0043377 negative regulation of CD8-positive, alpha-beta T cell differentiation http://purl.obolibrary.org/obo/GO_2001186 negative regulation of CD8-positive, alpha-beta T cell activation Any process that stops, prevents, or reduces the rate of CD8-positive, alpha-beta T cell differentiation. http://purl.obolibrary.org/obo/GO_0043378 positive regulation of CD8-positive, alpha-beta T cell differentiation http://purl.obolibrary.org/obo/GO_2001187 positive regulation of CD8-positive, alpha-beta T cell activation Any process that activates or increases the frequency, rate or extent of CD8-positive, alpha-beta T cell differentiation. http://purl.obolibrary.org/obo/GO_0043379 memory T cell differentiation http://purl.obolibrary.org/obo/GO_0090715 immunological memory formation process The process in which a newly activated T cell acquires specialized features of a memory T cell. http://purl.obolibrary.org/obo/GO_0043380 regulation of memory T cell differentiation http://purl.obolibrary.org/obo/GO_0045580 regulation of T cell differentiation Any process that modulates the frequency, rate, or extent of memory T cell differentiation. http://purl.obolibrary.org/obo/GO_0043381 negative regulation of memory T cell differentiation http://purl.obolibrary.org/obo/GO_0043380 regulation of memory T cell differentiation Any process that stops, prevents, or reduces the rate of memory T cell differentiation. http://purl.obolibrary.org/obo/GO_0043382 positive regulation of memory T cell differentiation http://purl.obolibrary.org/obo/GO_0043380 regulation of memory T cell differentiation Any process that activates or increases the frequency, rate or extent of memory T cell differentiation. http://purl.obolibrary.org/obo/GO_0043384 pre-T cell receptor complex http://purl.obolibrary.org/obo/GO_0098802 plasma membrane signaling receptor complex A receptor complex found on immature T cells consisting of a T cell receptor beta chain and the pre-TCR-alpha chain, along with additional signaling components including CD3 family members and additional signaling proteins. http://purl.obolibrary.org/obo/GO_0043388 positive regulation of DNA binding http://purl.obolibrary.org/obo/GO_0051101 regulation of DNA binding Any process that increases the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid). http://purl.obolibrary.org/obo/GO_0043392 negative regulation of DNA binding http://purl.obolibrary.org/obo/GO_0051101 regulation of DNA binding Any process that stops or reduces the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid). http://purl.obolibrary.org/obo/GO_0043394 proteoglycan binding http://purl.obolibrary.org/obo/GO_0097367 carbohydrate derivative binding Binding to a proteoglycan, any glycoprotein in which the carbohydrate units are glycosaminoglycans. http://purl.obolibrary.org/obo/GO_0043417 negative regulation of skeletal muscle tissue regeneration http://purl.obolibrary.org/obo/GO_0043416 regulation of skeletal muscle tissue regeneration Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle regeneration. http://purl.obolibrary.org/obo/GO_0043474 pigment metabolic process involved in pigmentation http://purl.obolibrary.org/obo/GO_0042440 pigment metabolic process The chemical reactions and pathways involving a pigment, any general or particular coloring matter in living organisms, resulting in the deposition or aggregation of pigment in an organism, tissue or cell. http://purl.obolibrary.org/obo/GO_0043523 regulation of neuron apoptotic process http://purl.obolibrary.org/obo/GO_0042981 regulation of apoptotic process Any process that modulates the occurrence or rate of cell death by apoptotic process in neurons. http://purl.obolibrary.org/obo/GO_0043524 negative regulation of neuron apoptotic process http://purl.obolibrary.org/obo/GO_0043523 regulation of neuron apoptotic process Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process in neurons. http://purl.obolibrary.org/obo/GO_0043525 positive regulation of neuron apoptotic process http://purl.obolibrary.org/obo/GO_0043065 positive regulation of apoptotic process Any process that activates or increases the frequency, rate or extent of cell death of neurons by apoptotic process. http://purl.obolibrary.org/obo/GO_0043535 regulation of blood vessel endothelial cell migration http://purl.obolibrary.org/obo/GO_0010594 regulation of endothelial cell migration Any process that modulates the frequency, rate or extent of the migration of the endothelial cells of blood vessels. http://purl.obolibrary.org/obo/GO_0043536 positive regulation of blood vessel endothelial cell migration http://purl.obolibrary.org/obo/GO_0010595 positive regulation of endothelial cell migration Any process that activates or increases the frequency, rate or extent of the migration of the endothelial cells of blood vessels. http://purl.obolibrary.org/obo/GO_0043537 negative regulation of blood vessel endothelial cell migration http://purl.obolibrary.org/obo/GO_0010596 negative regulation of endothelial cell migration Any process that stops, prevents, or reduces the frequency, rate or extent of the migration of the endothelial cells of blood vessels. http://purl.obolibrary.org/obo/GO_0043576 regulation of respiratory gaseous exchange http://purl.obolibrary.org/obo/GO_0051239 regulation of multicellular organismal process Any process that modulates the frequency, rate or extent of the process of gaseous exchange between an organism and its environment. http://purl.obolibrary.org/obo/GO_0043583 ear development http://purl.obolibrary.org/obo/GO_0007423 sensory organ development The process whose specific outcome is the progression of the ear over time, from its formation to the mature structure. The ear is the sense organ in vertebrates that is specialized for the detection of sound, and the maintenance of balance. Includes the outer ear and middle ear, which collect and transmit sound waves; and the inner ear, which contains the organs of balance and (except in fish) hearing. Also includes the pinna, the visible part of the outer ear, present in some mammals. http://purl.obolibrary.org/obo/GO_0043585 nose morphogenesis http://purl.obolibrary.org/obo/GO_0090596 sensory organ morphogenesis The process in which the anatomical structures of the nose are generated and organized. The nose is the specialized structure of the face that serves as the organ of the sense of smell and as part of the respiratory system. Includes the nasi externus (external nose) and cavitas nasi (nasal cavity). http://purl.obolibrary.org/obo/GO_0043586 tongue development http://purl.obolibrary.org/obo/GO_0007423 sensory organ development The process whose specific outcome is the progression of the tongue over time, from its formation to the mature structure. The tongue is the movable, muscular organ on the floor of the mouth of most vertebrates, in many other mammals is the principal organ of taste, aids in the prehension of food, in swallowing, and in modifying the voice as in speech. http://purl.obolibrary.org/obo/GO_0043587 tongue morphogenesis http://purl.obolibrary.org/obo/GO_0090596 sensory organ morphogenesis The process in which the anatomical structures of the tongue are generated and organized. The tongue is the movable, muscular organ on the floor of the mouth of most vertebrates, in man other mammals is the principal organ of taste, aids in the prehension of food, in swallowing, and in modifying the voice as in speech. http://purl.obolibrary.org/obo/GO_0043589 skin morphogenesis http://purl.obolibrary.org/obo/GO_0009887 animal organ morphogenesis The process in which the anatomical structures of the skin are generated and organized. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner, sensitive and vascular dermis (cutis, corium or true skin) composed mostly of connective tissue. http://purl.obolibrary.org/obo/GO_0043679 axon terminus http://purl.obolibrary.org/obo/GO_0044306 neuron projection terminus Terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters. The axon terminus is considered to be the whole region of thickening and the terminal button is a specialized region of it. http://purl.obolibrary.org/obo/GO_0043695 detection of pheromone http://purl.obolibrary.org/obo/GO_0019236 response to pheromone The series of events in which a pheromone stimulus is received by a cell and converted into a molecular signal. http://purl.obolibrary.org/obo/GO_0043931 ossification involved in bone maturation http://purl.obolibrary.org/obo/GO_0001503 ossification The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone, involved in the progression of the skeleton from its formation to its mature state. http://purl.obolibrary.org/obo/GO_0043932 ossification involved in bone remodeling http://purl.obolibrary.org/obo/GO_0001503 ossification The formation or growth of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone, involved in response to injury or other physical, physiological or environmental stress stimuli. http://purl.obolibrary.org/obo/GO_0043937 regulation of sporulation http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of sporulation, the process whose specific outcome is the progression of a spore over time, from its initiation to the mature structure. http://purl.obolibrary.org/obo/GO_0043938 positive regulation of sporulation http://purl.obolibrary.org/obo/GO_0043937 regulation of sporulation Any process that activates, maintains or increases the frequency, rate or extent of sporulation, the process whose specific outcome is the progression of a spore over time, from its initiation to the mature structure. http://purl.obolibrary.org/obo/GO_0043939 negative regulation of sporulation http://purl.obolibrary.org/obo/GO_0043937 regulation of sporulation Any process that stops, prevents, or reduces the frequency, rate or extent of sporulation, the process whose specific outcome is the progression of a spore over time, from its initiation to the mature structure. http://purl.obolibrary.org/obo/GO_0043940 regulation of sexual sporulation resulting in formation of a cellular spore http://purl.obolibrary.org/obo/GO_0042173 regulation of sporulation resulting in formation of a cellular spore Any process that modulates the frequency, rate or extent of the formation of cellular spores derived from the products of meiosis. http://purl.obolibrary.org/obo/GO_0043941 positive regulation of sexual sporulation resulting in formation of a cellular spore http://purl.obolibrary.org/obo/GO_0051446 positive regulation of meiotic cell cycle Any process that activates, maintains or increases the frequency, rate or extent of the formation of cellular spores derived from the products of meiosis. http://purl.obolibrary.org/obo/GO_0043942 negative regulation of sexual sporulation resulting in formation of a cellular spore http://purl.obolibrary.org/obo/GO_0051447 negative regulation of meiotic cell cycle Any process that stops, prevents, or reduces the frequency, rate or extent of the formation of cellular spores derived from the products of meiosis. http://purl.obolibrary.org/obo/GO_0044058 regulation of digestive system process http://purl.obolibrary.org/obo/GO_0044057 regulation of system process Any process that modulates the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism. http://purl.obolibrary.org/obo/GO_0044062 regulation of excretion http://purl.obolibrary.org/obo/GO_0044057 regulation of system process Any process that modulates the frequency, rate, or extent of excretion, the elimination by an organism of the waste products that arise as a result of metabolic activity. http://purl.obolibrary.org/obo/GO_0044090 positive regulation of vacuole organization http://purl.obolibrary.org/obo/GO_0010638 positive regulation of organelle organization Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a vacuole. http://purl.obolibrary.org/obo/GO_0044207 translation initiation ternary complex http://purl.obolibrary.org/obo/GO_1990904 ribonucleoprotein complex A ribonucleoprotein complex that contains aminoacylated initiator methionine tRNA, GTP, and initiation factor 2 (either eIF2 in eukaryotes, or IF2 in prokaryotes). In prokaryotes, fMet-tRNA (initiator) is used rather than Met-tRNA (initiator). http://purl.obolibrary.org/obo/GO_0044258 intestinal lipid catabolic process http://purl.obolibrary.org/obo/GO_0016042 lipid catabolic process The chemical reactions and pathways resulting in the breakdown into fatty acids and monoglycerides of lipids in the small intestine. Lipids are broken down by lipases released by the pancreas. http://purl.obolibrary.org/obo/GO_0044292 dendrite terminus http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure A structure at the distal end of a dendrite adapted to carry out a specific function, e.g. dendriole. http://purl.obolibrary.org/obo/GO_0044293 dendriole http://purl.obolibrary.org/obo/GO_0044292 dendrite terminus Small dendrites that makes up a brush structure found as the terminal specialization of a dendrite of a unipolar brush cell (UBC). http://purl.obolibrary.org/obo/GO_0044297 cell body http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure The portion of a cell bearing surface projections such as axons, dendrites, cilia, or flagella that includes the nucleus, but excludes all cell projections. http://purl.obolibrary.org/obo/GO_0044306 neuron projection terminus http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure The specialized, terminal region of a neuron projection such as an axon or a dendrite. http://purl.obolibrary.org/obo/GO_0044316 cone cell pedicle http://purl.obolibrary.org/obo/GO_0043679 axon terminus A specialized axon terminus which is produced by retinal cone cells. Pedicles are large, conical, flat end-feet (8-10 micrometers diameter) of the retinal cone axon that lie more or less side by side on the same plane at the outer edge of the outer plexiform layer (OPL). http://purl.obolibrary.org/obo/GO_0044342 type B pancreatic cell proliferation http://purl.obolibrary.org/obo/GO_0050673 epithelial cell proliferation The multiplication or reproduction of pancreatic B cells, resulting in the expansion of an pancreatic B cell population. Pancreatic B cell are cells of the pancreas that secrete insulin. http://purl.obolibrary.org/obo/GO_0044346 fibroblast apoptotic process http://purl.obolibrary.org/obo/GO_0006915 apoptotic process Any apoptotic process in a fibroblast, a connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. http://purl.obolibrary.org/obo/GO_0044380 protein localization to cytoskeleton http://purl.obolibrary.org/obo/GO_0033365 protein localization to organelle A process in which a protein is transported to, or maintained in, a location within the cytoskeleton. http://purl.obolibrary.org/obo/GO_0044458 motile cilium assembly http://purl.obolibrary.org/obo/GO_0060271 cilium assembly The aggregation, arrangement and bonding together of a set of components to form a motile cilium. http://purl.obolibrary.org/obo/GO_0044565 dendritic cell proliferation http://purl.obolibrary.org/obo/GO_0032943 mononuclear cell proliferation The expansion of a dendritic cell population by cell division. A dendritic cell is a cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation. http://purl.obolibrary.org/obo/GO_0044566 chondrocyte activation http://purl.obolibrary.org/obo/GO_0001775 cell activation A change in the morphology or behavior of a chondrocyte resulting from exposure to an activating factor such as a cellular or soluble ligand. A chondrocyte is a polymorphic cell that forms cartilage. http://purl.obolibrary.org/obo/GO_0044872 lipoprotein localization http://purl.obolibrary.org/obo/GO_0033036 macromolecule localization Any process in which a lipoprotein is transported to, or maintained in, a specific location. http://purl.obolibrary.org/obo/GO_0044873 lipoprotein localization to membrane http://purl.obolibrary.org/obo/GO_0044872 lipoprotein localization A process in which a lipoprotein is transported to, or maintained in, a specific location in a membrane. http://purl.obolibrary.org/obo/GO_0044874 lipoprotein localization to outer membrane http://purl.obolibrary.org/obo/GO_0044873 lipoprotein localization to membrane A process in which a lipoprotein is transported to, or maintained in, a specific location in an outer membrane. http://purl.obolibrary.org/obo/GO_0045019 negative regulation of nitric oxide biosynthetic process http://purl.obolibrary.org/obo/GO_0009890 negative regulation of biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nitric oxide. http://purl.obolibrary.org/obo/GO_0045031 G protein-coupled ATP receptor activity http://purl.obolibrary.org/obo/GO_0045028 G protein-coupled purinergic nucleotide receptor activity Combining with ATP and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. http://purl.obolibrary.org/obo/GO_0045037 protein import into chloroplast stroma http://purl.obolibrary.org/obo/GO_0072598 protein localization to chloroplast The targeting and import of proteins into the chloroplast stroma. Import depends on ATP hydrolysis catalyzed by stromal chaperones. Chloroplast stromal proteins, such as the S subunit of rubisco, have a N-terminal stromal-import sequence of about 44 amino acids which is cleaved from the protein precursor after import. http://purl.obolibrary.org/obo/GO_0045058 T cell selection http://purl.obolibrary.org/obo/GO_0002376 immune system process The process in which T cells that express T cell receptors that are restricted by self MHC protein complexes and tolerant to self antigens are selected for further maturation. http://purl.obolibrary.org/obo/GO_0045095 keratin filament http://purl.obolibrary.org/obo/GO_0005882 intermediate filament A filament composed of acidic and basic keratins (types I and II), typically expressed in epithelial cells. The keratins are the most diverse classes of IF proteins, with a large number of keratin isoforms being expressed. Each type of epithelium always expresses a characteristic combination of type I and type II keratins. http://purl.obolibrary.org/obo/GO_0045103 intermediate filament-based process http://purl.obolibrary.org/obo/GO_0009987 cellular process Any cellular process that depends upon or alters the intermediate filament cytoskeleton, that part of the cytoskeleton comprising intermediate filaments and their associated proteins. http://purl.obolibrary.org/obo/GO_0045104 intermediate filament cytoskeleton organization http://purl.obolibrary.org/obo/GO_0045103 intermediate filament-based process A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising intermediate filaments and their associated proteins. http://purl.obolibrary.org/obo/GO_0045109 intermediate filament organization http://purl.obolibrary.org/obo/GO_0045104 intermediate filament cytoskeleton organization Control of the spatial distribution of intermediate filaments; includes organizing filaments into meshworks, bundles, or other structures, as by cross-linking. http://purl.obolibrary.org/obo/GO_0045124 regulation of bone resorption http://purl.obolibrary.org/obo/GO_0046850 regulation of bone remodeling Any process that modulates the frequency, rate or extent of bone tissue loss (resorption). http://purl.obolibrary.org/obo/GO_0045144 meiotic sister chromatid segregation http://purl.obolibrary.org/obo/GO_0000819 sister chromatid segregation The cell cycle process in which sister chromatids are organized and then physically separated and randomly apportioned to two sets during the second division of the meiotic cell cycle. http://purl.obolibrary.org/obo/GO_0045190 isotype switching http://purl.obolibrary.org/obo/GO_0002312 B cell activation involved in immune response The switching of activated B cells from IgM biosynthesis to biosynthesis of other isotypes of immunoglobulin, accomplished through a recombination process involving an intrachromosomal deletion involving switch regions that reside 5' of each constant region gene segment in the immunoglobulin heavy chain locus. http://purl.obolibrary.org/obo/GO_0045191 regulation of isotype switching http://purl.obolibrary.org/obo/GO_0050864 regulation of B cell activation Any process that modulates the frequency, rate or extent of isotype switching. http://purl.obolibrary.org/obo/GO_0045196 establishment or maintenance of neuroblast polarity http://purl.obolibrary.org/obo/GO_0007163 establishment or maintenance of cell polarity Any cellular process that results in the specification, formation or maintenance of the apicobasal polarity of a neuroblast cell, a progenitor of the central nervous system. http://purl.obolibrary.org/obo/GO_0045200 establishment of neuroblast polarity http://purl.obolibrary.org/obo/GO_0045196 establishment or maintenance of neuroblast polarity The specification and formation of the apicobasal polarity of a neuroblast cell, a progenitor of the central nervous system. http://purl.obolibrary.org/obo/GO_0045211 postsynaptic membrane http://purl.obolibrary.org/obo/GO_0097060 synaptic membrane A specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). Neurotransmitters cross the synaptic cleft and transmit the signal to the postsynaptic membrane. http://purl.obolibrary.org/obo/GO_0045296 cadherin binding http://purl.obolibrary.org/obo/GO_0050839 cell adhesion molecule binding Binding to cadherin, a type I membrane protein involved in cell adhesion. http://purl.obolibrary.org/obo/GO_0045314 regulation of compound eye photoreceptor development http://purl.obolibrary.org/obo/GO_0042478 regulation of eye photoreceptor cell development Any process that modulates the frequency, rate or extent of compound eye photoreceptor development. http://purl.obolibrary.org/obo/GO_0045315 positive regulation of compound eye photoreceptor development http://purl.obolibrary.org/obo/GO_0045314 regulation of compound eye photoreceptor development Any process that activates or increases the frequency, rate or extent of compound eye photoreceptor development. http://purl.obolibrary.org/obo/GO_0045316 negative regulation of compound eye photoreceptor development http://purl.obolibrary.org/obo/GO_0045314 regulation of compound eye photoreceptor development Any process that stops, prevents, or reduces the frequency, rate or extent of compound eye photoreceptor development. http://purl.obolibrary.org/obo/GO_0045428 regulation of nitric oxide biosynthetic process http://purl.obolibrary.org/obo/GO_0009889 regulation of biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nitric oxide. http://purl.obolibrary.org/obo/GO_0045429 positive regulation of nitric oxide biosynthetic process http://purl.obolibrary.org/obo/GO_0009891 positive regulation of biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nitric oxide. http://purl.obolibrary.org/obo/GO_0045444 fat cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires specialized features of an adipocyte, an animal connective tissue cell specialized for the synthesis and storage of fat. http://purl.obolibrary.org/obo/GO_0045453 bone resorption http://purl.obolibrary.org/obo/GO_0001894 tissue homeostasis The process in which specialized cells known as osteoclasts degrade the organic and inorganic portions of bone, and endocytose and transport the degradation products. http://purl.obolibrary.org/obo/GO_0045463 R8 cell development http://purl.obolibrary.org/obo/GO_0042051 compound eye photoreceptor development The process whose specific outcome is the progression of the R8 photoreceptor over time, from its formation to the mature structure. The R8 photoreceptor is the founding receptor of each ommatidium. http://purl.obolibrary.org/obo/GO_0045467 R7 cell development http://purl.obolibrary.org/obo/GO_0042051 compound eye photoreceptor development The process whose specific outcome is the progression of the R7 photoreceptor over time, from its formation to the mature structure. The R7 photoreceptor is the last photoreceptor to develop in the ommatidium. http://purl.obolibrary.org/obo/GO_0045476 nurse cell apoptotic process http://purl.obolibrary.org/obo/GO_0010623 programmed cell death involved in cell development Any apoptotic process in a nurse cell. During late oogenesis, following the transfer of substances from the nurse cells to the oocyte, nurse cell remnants are cleared from the egg chamber by apoptotic process. http://purl.obolibrary.org/obo/GO_0045477 regulation of nurse cell apoptotic process http://purl.obolibrary.org/obo/GO_2000241 regulation of reproductive process Any process that modulates the frequency, rate or extent of nurse cell apoptotic process. http://purl.obolibrary.org/obo/GO_0045570 regulation of imaginal disc growth http://purl.obolibrary.org/obo/GO_0048638 regulation of developmental growth Any process that modulates the frequency, rate or extent of the growth of the imaginal disc. http://purl.obolibrary.org/obo/GO_0045571 negative regulation of imaginal disc growth http://purl.obolibrary.org/obo/GO_0045570 regulation of imaginal disc growth Any process that stops, prevents, or reduces the frequency, rate or extent of imaginal disc growth. http://purl.obolibrary.org/obo/GO_0045572 positive regulation of imaginal disc growth http://purl.obolibrary.org/obo/GO_0048639 positive regulation of developmental growth Any process that activates or increases the frequency, rate or extent of imaginal disc growth. http://purl.obolibrary.org/obo/GO_0045583 regulation of cytotoxic T cell differentiation http://purl.obolibrary.org/obo/GO_0045580 regulation of T cell differentiation Any process that modulates the frequency, rate or extent of cytotoxic T cell differentiation. http://purl.obolibrary.org/obo/GO_0045584 negative regulation of cytotoxic T cell differentiation http://purl.obolibrary.org/obo/GO_0045583 regulation of cytotoxic T cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of cytotoxic T cell differentiation. http://purl.obolibrary.org/obo/GO_0045585 positive regulation of cytotoxic T cell differentiation http://purl.obolibrary.org/obo/GO_0045583 regulation of cytotoxic T cell differentiation Any process that activates or increases the frequency, rate or extent of cytotoxic T cell differentiation. http://purl.obolibrary.org/obo/GO_0045586 regulation of gamma-delta T cell differentiation http://purl.obolibrary.org/obo/GO_0046643 regulation of gamma-delta T cell activation Any process that modulates the frequency, rate or extent of gamma-delta T cell differentiation. http://purl.obolibrary.org/obo/GO_0045587 negative regulation of gamma-delta T cell differentiation http://purl.obolibrary.org/obo/GO_0046644 negative regulation of gamma-delta T cell activation Any process that stops, prevents, or reduces the frequency, rate or extent of gamma-delta T cell differentiation. http://purl.obolibrary.org/obo/GO_0045588 positive regulation of gamma-delta T cell differentiation http://purl.obolibrary.org/obo/GO_0046645 positive regulation of gamma-delta T cell activation Any process that activates or increases the frequency, rate or extent of gamma-delta T cell differentiation. http://purl.obolibrary.org/obo/GO_0045592 regulation of cumulus cell differentiation http://purl.obolibrary.org/obo/GO_2000387 regulation of antral ovarian follicle growth Any process that modulates the frequency, rate or extent of ovarian cumulus cell differentiation. http://purl.obolibrary.org/obo/GO_0045593 negative regulation of cumulus cell differentiation http://purl.obolibrary.org/obo/GO_2000242 negative regulation of reproductive process Any process that stops, prevents, or reduces the frequency, rate or extent of ovarian cumulus cell differentiation. http://purl.obolibrary.org/obo/GO_0045594 positive regulation of cumulus cell differentiation http://purl.obolibrary.org/obo/GO_2000243 positive regulation of reproductive process Any process that activates or increases the frequency, rate or extent of ovarian cumulus cell differentiation. http://purl.obolibrary.org/obo/GO_0045598 regulation of fat cell differentiation http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the frequency, rate or extent of adipocyte differentiation. http://purl.obolibrary.org/obo/GO_0045599 negative regulation of fat cell differentiation http://purl.obolibrary.org/obo/GO_0045598 regulation of fat cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of adipocyte differentiation. http://purl.obolibrary.org/obo/GO_0045600 positive regulation of fat cell differentiation http://purl.obolibrary.org/obo/GO_0045597 positive regulation of cell differentiation Any process that activates or increases the frequency, rate or extent of adipocyte differentiation. http://purl.obolibrary.org/obo/GO_0045601 regulation of endothelial cell differentiation http://purl.obolibrary.org/obo/GO_0030856 regulation of epithelial cell differentiation Any process that modulates the frequency, rate or extent of endothelial cell differentiation. http://purl.obolibrary.org/obo/GO_0045602 negative regulation of endothelial cell differentiation http://purl.obolibrary.org/obo/GO_0045601 regulation of endothelial cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of endothelial cell differentiation. http://purl.obolibrary.org/obo/GO_0045603 positive regulation of endothelial cell differentiation http://purl.obolibrary.org/obo/GO_0045601 regulation of endothelial cell differentiation Any process that activates or increases the frequency, rate or extent of endothelial cell differentiation. http://purl.obolibrary.org/obo/GO_0045604 regulation of epidermal cell differentiation http://purl.obolibrary.org/obo/GO_0045682 regulation of epidermis development Any process that modulates the frequency, rate or extent of epidermal cell differentiation. http://purl.obolibrary.org/obo/GO_0045605 negative regulation of epidermal cell differentiation http://purl.obolibrary.org/obo/GO_0045683 negative regulation of epidermis development Any process that stops, prevents, or reduces the frequency, rate or extent of epidermal cell differentiation. http://purl.obolibrary.org/obo/GO_0045606 positive regulation of epidermal cell differentiation http://purl.obolibrary.org/obo/GO_0045684 positive regulation of epidermis development Any process that activates or increases the frequency, rate or extent of epidermal cell differentiation. http://purl.obolibrary.org/obo/GO_0045607 regulation of inner ear auditory receptor cell differentiation http://purl.obolibrary.org/obo/GO_2000980 regulation of inner ear receptor cell differentiation Any process that modulates the frequency, rate or extent of auditory hair cell differentiation. http://purl.obolibrary.org/obo/GO_0045609 positive regulation of inner ear auditory receptor cell differentiation http://purl.obolibrary.org/obo/GO_2000982 positive regulation of inner ear receptor cell differentiation Any process that activates or increases the frequency, rate or extent of auditory hair cell differentiation. http://purl.obolibrary.org/obo/GO_0045610 regulation of hemocyte differentiation http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the frequency, rate or extent of hemocyte differentiation. http://purl.obolibrary.org/obo/GO_0045611 negative regulation of hemocyte differentiation http://purl.obolibrary.org/obo/GO_0045610 regulation of hemocyte differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of hemocyte differentiation. http://purl.obolibrary.org/obo/GO_0045612 positive regulation of hemocyte differentiation http://purl.obolibrary.org/obo/GO_0045597 positive regulation of cell differentiation Any process that activates or increases the frequency, rate or extent of hemocyte differentiation. http://purl.obolibrary.org/obo/GO_0045613 regulation of plasmatocyte differentiation http://purl.obolibrary.org/obo/GO_0045610 regulation of hemocyte differentiation Any process that modulates the frequency, rate or extent of plasmatocyte differentiation. http://purl.obolibrary.org/obo/GO_0045614 negative regulation of plasmatocyte differentiation http://purl.obolibrary.org/obo/GO_0045613 regulation of plasmatocyte differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of plasmatocyte differentiation. http://purl.obolibrary.org/obo/GO_0045615 positive regulation of plasmatocyte differentiation http://purl.obolibrary.org/obo/GO_0045613 regulation of plasmatocyte differentiation Any process that activates or increases the frequency, rate or extent of plasmatocyte differentiation. http://purl.obolibrary.org/obo/GO_0045616 regulation of keratinocyte differentiation http://purl.obolibrary.org/obo/GO_0045604 regulation of epidermal cell differentiation Any process that modulates the frequency, rate or extent of keratinocyte differentiation. http://purl.obolibrary.org/obo/GO_0045617 negative regulation of keratinocyte differentiation http://purl.obolibrary.org/obo/GO_0045616 regulation of keratinocyte differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of keratinocyte differentiation. http://purl.obolibrary.org/obo/GO_0045618 positive regulation of keratinocyte differentiation http://purl.obolibrary.org/obo/GO_0045616 regulation of keratinocyte differentiation Any process that activates or increases the frequency, rate or extent of keratinocyte differentiation. http://purl.obolibrary.org/obo/GO_0045622 regulation of T-helper cell differentiation http://purl.obolibrary.org/obo/GO_0043370 regulation of CD4-positive, alpha-beta T cell differentiation Any process that modulates the frequency, rate or extent of T-helper cell differentiation. http://purl.obolibrary.org/obo/GO_0045623 negative regulation of T-helper cell differentiation http://purl.obolibrary.org/obo/GO_0045622 regulation of T-helper cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of T-helper cell differentiation. http://purl.obolibrary.org/obo/GO_0045624 positive regulation of T-helper cell differentiation http://purl.obolibrary.org/obo/GO_0045622 regulation of T-helper cell differentiation Any process that activates or increases the frequency, rate or extent of T-helper cell differentiation. http://purl.obolibrary.org/obo/GO_0045625 regulation of T-helper 1 cell differentiation http://purl.obolibrary.org/obo/GO_0045622 regulation of T-helper cell differentiation Any process that modulates the frequency, rate or extent of T-helper 1 cell differentiation. http://purl.obolibrary.org/obo/GO_0045626 negative regulation of T-helper 1 cell differentiation http://purl.obolibrary.org/obo/GO_0045625 regulation of T-helper 1 cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of T-helper 1 cell differentiation. http://purl.obolibrary.org/obo/GO_0045627 positive regulation of T-helper 1 cell differentiation http://purl.obolibrary.org/obo/GO_0045625 regulation of T-helper 1 cell differentiation Any process that activates or increases the frequency, rate or extent of T-helper 1 cell differentiation. http://purl.obolibrary.org/obo/GO_0045628 regulation of T-helper 2 cell differentiation http://purl.obolibrary.org/obo/GO_0045622 regulation of T-helper cell differentiation Any process that modulates the frequency, rate or extent of T-helper 2 cell differentiation. http://purl.obolibrary.org/obo/GO_0045629 negative regulation of T-helper 2 cell differentiation http://purl.obolibrary.org/obo/GO_0045628 regulation of T-helper 2 cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of T-helper 2 cell differentiation. http://purl.obolibrary.org/obo/GO_0045630 positive regulation of T-helper 2 cell differentiation http://purl.obolibrary.org/obo/GO_0045628 regulation of T-helper 2 cell differentiation Any process that activates or increases the frequency, rate or extent of T-helper 2 cell differentiation. http://purl.obolibrary.org/obo/GO_0045631 regulation of mechanoreceptor differentiation http://purl.obolibrary.org/obo/GO_0045664 regulation of neuron differentiation Any process that modulates the frequency, rate or extent of mechanoreceptor differentiation. http://purl.obolibrary.org/obo/GO_0045632 negative regulation of mechanoreceptor differentiation http://purl.obolibrary.org/obo/GO_0045665 negative regulation of neuron differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of mechanoreceptor differentiation. http://purl.obolibrary.org/obo/GO_0045633 positive regulation of mechanoreceptor differentiation http://purl.obolibrary.org/obo/GO_0045666 positive regulation of neuron differentiation Any process that activates or increases the frequency, rate or extent of mechanoreceptor differentiation. http://purl.obolibrary.org/obo/GO_0045634 regulation of melanocyte differentiation http://purl.obolibrary.org/obo/GO_0050932 regulation of pigment cell differentiation Any process that modulates the frequency, rate or extent of melanocyte differentiation. http://purl.obolibrary.org/obo/GO_0045635 negative regulation of melanocyte differentiation http://purl.obolibrary.org/obo/GO_0050941 negative regulation of pigment cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of melanocyte differentiation. http://purl.obolibrary.org/obo/GO_0045636 positive regulation of melanocyte differentiation http://purl.obolibrary.org/obo/GO_0050942 positive regulation of pigment cell differentiation Any process that activates or increases the frequency, rate or extent of melanocyte differentiation. http://purl.obolibrary.org/obo/GO_0045640 regulation of basophil differentiation http://purl.obolibrary.org/obo/GO_0030852 regulation of granulocyte differentiation Any process that modulates the frequency, rate or extent of basophil differentiation. http://purl.obolibrary.org/obo/GO_0045641 negative regulation of basophil differentiation http://purl.obolibrary.org/obo/GO_0045640 regulation of basophil differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of basophil differentiation. http://purl.obolibrary.org/obo/GO_0045642 positive regulation of basophil differentiation http://purl.obolibrary.org/obo/GO_0045640 regulation of basophil differentiation Any process that activates or increases the frequency, rate or extent of basophil differentiation. http://purl.obolibrary.org/obo/GO_0045643 regulation of eosinophil differentiation http://purl.obolibrary.org/obo/GO_0030852 regulation of granulocyte differentiation Any process that modulates the frequency, rate or extent of eosinophil differentiation. http://purl.obolibrary.org/obo/GO_0045644 negative regulation of eosinophil differentiation http://purl.obolibrary.org/obo/GO_0045643 regulation of eosinophil differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of eosinophil differentiation. http://purl.obolibrary.org/obo/GO_0045645 positive regulation of eosinophil differentiation http://purl.obolibrary.org/obo/GO_0045643 regulation of eosinophil differentiation Any process that activates or increases the frequency, rate or extent of eosinophil differentiation. http://purl.obolibrary.org/obo/GO_0045647 negative regulation of erythrocyte differentiation http://purl.obolibrary.org/obo/GO_0045646 regulation of erythrocyte differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of erythrocyte differentiation. http://purl.obolibrary.org/obo/GO_0045648 positive regulation of erythrocyte differentiation http://purl.obolibrary.org/obo/GO_0045646 regulation of erythrocyte differentiation Any process that activates or increases the frequency, rate or extent of erythrocyte differentiation. http://purl.obolibrary.org/obo/GO_0045652 regulation of megakaryocyte differentiation http://purl.obolibrary.org/obo/GO_0045637 regulation of myeloid cell differentiation Any process that modulates the frequency, rate or extent of megakaryocyte differentiation. http://purl.obolibrary.org/obo/GO_0045653 negative regulation of megakaryocyte differentiation http://purl.obolibrary.org/obo/GO_0045652 regulation of megakaryocyte differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of megakaryocyte differentiation. http://purl.obolibrary.org/obo/GO_0045654 positive regulation of megakaryocyte differentiation http://purl.obolibrary.org/obo/GO_0045652 regulation of megakaryocyte differentiation Any process that activates or increases the frequency, rate or extent of megakaryocyte differentiation. http://purl.obolibrary.org/obo/GO_0045655 regulation of monocyte differentiation http://purl.obolibrary.org/obo/GO_0002761 regulation of myeloid leukocyte differentiation Any process that modulates the frequency, rate or extent of monocyte differentiation. http://purl.obolibrary.org/obo/GO_0045656 negative regulation of monocyte differentiation http://purl.obolibrary.org/obo/GO_0045655 regulation of monocyte differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of monocyte differentiation. http://purl.obolibrary.org/obo/GO_0045657 positive regulation of monocyte differentiation http://purl.obolibrary.org/obo/GO_0045655 regulation of monocyte differentiation Any process that activates or increases the frequency, rate or extent of monocyte differentiation. http://purl.obolibrary.org/obo/GO_0045658 regulation of neutrophil differentiation http://purl.obolibrary.org/obo/GO_0030852 regulation of granulocyte differentiation Any process that modulates the frequency, rate or extent of neutrophil differentiation. http://purl.obolibrary.org/obo/GO_0045659 negative regulation of neutrophil differentiation http://purl.obolibrary.org/obo/GO_0045658 regulation of neutrophil differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of neutrophil differentiation. http://purl.obolibrary.org/obo/GO_0045660 positive regulation of neutrophil differentiation http://purl.obolibrary.org/obo/GO_0045658 regulation of neutrophil differentiation Any process that activates or increases the frequency, rate or extent of neutrophil differentiation. http://purl.obolibrary.org/obo/GO_0045661 regulation of myoblast differentiation http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. http://purl.obolibrary.org/obo/GO_0045662 negative regulation of myoblast differentiation http://purl.obolibrary.org/obo/GO_0045661 regulation of myoblast differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. http://purl.obolibrary.org/obo/GO_0045663 positive regulation of myoblast differentiation http://purl.obolibrary.org/obo/GO_0045597 positive regulation of cell differentiation Any process that activates or increases the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. http://purl.obolibrary.org/obo/GO_0045667 regulation of osteoblast differentiation http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the frequency, rate or extent of osteoblast differentiation. http://purl.obolibrary.org/obo/GO_0045668 negative regulation of osteoblast differentiation http://purl.obolibrary.org/obo/GO_0045667 regulation of osteoblast differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of osteoblast differentiation. http://purl.obolibrary.org/obo/GO_0045669 positive regulation of osteoblast differentiation http://purl.obolibrary.org/obo/GO_0045597 positive regulation of cell differentiation Any process that activates or increases the frequency, rate or extent of osteoblast differentiation. http://purl.obolibrary.org/obo/GO_0045670 regulation of osteoclast differentiation http://purl.obolibrary.org/obo/GO_0002761 regulation of myeloid leukocyte differentiation Any process that modulates the frequency, rate or extent of osteoclast differentiation. http://purl.obolibrary.org/obo/GO_0045671 negative regulation of osteoclast differentiation http://purl.obolibrary.org/obo/GO_0045670 regulation of osteoclast differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of osteoclast differentiation. http://purl.obolibrary.org/obo/GO_0045672 positive regulation of osteoclast differentiation http://purl.obolibrary.org/obo/GO_0045670 regulation of osteoclast differentiation Any process that activates or increases the frequency, rate or extent of osteoclast differentiation. http://purl.obolibrary.org/obo/GO_0045676 regulation of R7 cell differentiation http://purl.obolibrary.org/obo/GO_0110116 regulation of compound eye photoreceptor cell differentiation Any process that modulates the frequency, rate or extent of R7 differentiation. http://purl.obolibrary.org/obo/GO_0045677 negative regulation of R7 cell differentiation http://purl.obolibrary.org/obo/GO_0045676 regulation of R7 cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of R7cell differentiation. http://purl.obolibrary.org/obo/GO_0045678 positive regulation of R7 cell differentiation http://purl.obolibrary.org/obo/GO_0045676 regulation of R7 cell differentiation Any process that activates or increases the frequency, rate or extent of R7 cell differentiation. http://purl.obolibrary.org/obo/GO_0045679 regulation of R8 cell differentiation http://purl.obolibrary.org/obo/GO_0110116 regulation of compound eye photoreceptor cell differentiation Any process that modulates the frequency, rate or extent of R8 differentiation. http://purl.obolibrary.org/obo/GO_0045680 negative regulation of R8 cell differentiation http://purl.obolibrary.org/obo/GO_0045679 regulation of R8 cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of R8 cell differentiation. http://purl.obolibrary.org/obo/GO_0045681 positive regulation of R8 cell differentiation http://purl.obolibrary.org/obo/GO_0045679 regulation of R8 cell differentiation Any process that activates or increases the frequency, rate or extent of R8 cell differentiation. http://purl.obolibrary.org/obo/GO_0045682 regulation of epidermis development http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of epidermis development. http://purl.obolibrary.org/obo/GO_0045683 negative regulation of epidermis development http://purl.obolibrary.org/obo/GO_0045682 regulation of epidermis development Any process that stops, prevents, or reduces the frequency, rate or extent of epidermis development. http://purl.obolibrary.org/obo/GO_0045684 positive regulation of epidermis development http://purl.obolibrary.org/obo/GO_0045682 regulation of epidermis development Any process that activates or increases the frequency, rate or extent of epidermis development. http://purl.obolibrary.org/obo/GO_0045700 regulation of spermatid nuclear differentiation http://purl.obolibrary.org/obo/GO_1903353 regulation of nucleus organization Any process that modulates the frequency, rate or extent of spermatid nuclear differentiation. http://purl.obolibrary.org/obo/GO_0045701 negative regulation of spermatid nuclear differentiation http://purl.obolibrary.org/obo/GO_2000242 negative regulation of reproductive process Any process that stops, prevents, or reduces the frequency, rate or extent of spermatid nuclear differentiation. http://purl.obolibrary.org/obo/GO_0045702 positive regulation of spermatid nuclear differentiation http://purl.obolibrary.org/obo/GO_2000243 positive regulation of reproductive process Any process that activates or increases the frequency, rate or extent of spermatid nuclear differentiation. http://purl.obolibrary.org/obo/GO_0045719 negative regulation of glycogen biosynthetic process http://purl.obolibrary.org/obo/GO_0070874 negative regulation of glycogen metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen. http://purl.obolibrary.org/obo/GO_0045721 negative regulation of gluconeogenesis http://purl.obolibrary.org/obo/GO_0045912 negative regulation of carbohydrate metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of gluconeogenesis. http://purl.obolibrary.org/obo/GO_0045722 positive regulation of gluconeogenesis http://purl.obolibrary.org/obo/GO_0010907 positive regulation of glucose metabolic process Any process that activates or increases the frequency, rate or extent of gluconeogenesis. http://purl.obolibrary.org/obo/GO_0045723 positive regulation of fatty acid biosynthetic process http://purl.obolibrary.org/obo/GO_0046889 positive regulation of lipid biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids. http://purl.obolibrary.org/obo/GO_0045724 positive regulation of cilium assembly http://purl.obolibrary.org/obo/GO_0120034 positive regulation of plasma membrane bounded cell projection assembly Any process that activates or increases the frequency, rate or extent of the formation of a cilium. http://purl.obolibrary.org/obo/GO_0045725 positive regulation of glycogen biosynthetic process http://purl.obolibrary.org/obo/GO_0070875 positive regulation of glycogen metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen. http://purl.obolibrary.org/obo/GO_0045729 respiratory burst at fertilization http://purl.obolibrary.org/obo/GO_0045730 respiratory burst The phase of elevated metabolic activity, during which oxygen consumption increases, that occurs at fertilization. An enhanced uptake of oxygen leads to the production of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals. Capacitation, a necessary prerequisite event to successful fertilization, can be induced by reactive oxygen species in vitro; hydrogen peroxide is used as an extracellular oxidant to cross-link the protective surface envelopes. http://purl.obolibrary.org/obo/GO_0045732 positive regulation of protein catabolic process http://purl.obolibrary.org/obo/GO_0009896 positive regulation of catabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds. http://purl.obolibrary.org/obo/GO_0045745 positive regulation of G protein-coupled receptor signaling pathway http://purl.obolibrary.org/obo/GO_0008277 regulation of G protein-coupled receptor signaling pathway Any process that activates or increases the frequency, rate or extent of G protein-coupled receptor signaling pathway activity. http://purl.obolibrary.org/obo/GO_0045759 negative regulation of action potential http://purl.obolibrary.org/obo/GO_0098900 regulation of action potential Any process that stops, prevents, or reduces the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels. http://purl.obolibrary.org/obo/GO_0045760 positive regulation of action potential http://purl.obolibrary.org/obo/GO_0098900 regulation of action potential Any process that activates or increases the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels. http://purl.obolibrary.org/obo/GO_0045766 positive regulation of angiogenesis http://purl.obolibrary.org/obo/GO_0045765 regulation of angiogenesis Any process that activates or increases angiogenesis. http://purl.obolibrary.org/obo/GO_0045769 negative regulation of asymmetric cell division http://purl.obolibrary.org/obo/GO_0009786 regulation of asymmetric cell division Any process that stops, prevents, or reduces the frequency, rate or extent of asymmetric cell division. http://purl.obolibrary.org/obo/GO_0045770 positive regulation of asymmetric cell division http://purl.obolibrary.org/obo/GO_0009786 regulation of asymmetric cell division Any process that activates or increases the frequency, rate or extent of asymmetric cell division. http://purl.obolibrary.org/obo/GO_0045779 negative regulation of bone resorption http://purl.obolibrary.org/obo/GO_0046851 negative regulation of bone remodeling Any process that stops, prevents, or reduces the frequency, rate or extent of bone resorption. http://purl.obolibrary.org/obo/GO_0045780 positive regulation of bone resorption http://purl.obolibrary.org/obo/GO_0045124 regulation of bone resorption Any process that activates or increases the frequency, rate or extent of bone resorption. http://purl.obolibrary.org/obo/GO_0045787 positive regulation of cell cycle http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the rate or extent of progression through the cell cycle. http://purl.obolibrary.org/obo/GO_0045881 positive regulation of sporulation resulting in formation of a cellular spore http://purl.obolibrary.org/obo/GO_0043938 positive regulation of sporulation Any process that activates or increases the frequency, rate or extent of sporulation. http://purl.obolibrary.org/obo/GO_0045922 negative regulation of fatty acid metabolic process http://purl.obolibrary.org/obo/GO_0045833 negative regulation of lipid metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving fatty acids. http://purl.obolibrary.org/obo/GO_0045923 positive regulation of fatty acid metabolic process http://purl.obolibrary.org/obo/GO_0045834 positive regulation of lipid metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving fatty acids. http://purl.obolibrary.org/obo/GO_0045937 positive regulation of phosphate metabolic process http://purl.obolibrary.org/obo/GO_0010562 positive regulation of phosphorus metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving phosphates. http://purl.obolibrary.org/obo/GO_0046013 regulation of T cell homeostatic proliferation http://purl.obolibrary.org/obo/GO_0042129 regulation of T cell proliferation Any process that modulates the frequency, rate or extent of resting T cell proliferation. http://purl.obolibrary.org/obo/GO_0046532 regulation of photoreceptor cell differentiation http://purl.obolibrary.org/obo/GO_0045664 regulation of neuron differentiation Any process that modulates the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster. http://purl.obolibrary.org/obo/GO_0046533 negative regulation of photoreceptor cell differentiation http://purl.obolibrary.org/obo/GO_0045665 negative regulation of neuron differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster. http://purl.obolibrary.org/obo/GO_0046534 positive regulation of photoreceptor cell differentiation http://purl.obolibrary.org/obo/GO_0045666 positive regulation of neuron differentiation Any process that activates or increases the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster. http://purl.obolibrary.org/obo/GO_0046621 negative regulation of organ growth http://purl.obolibrary.org/obo/GO_0048640 negative regulation of developmental growth Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organ of an organism. http://purl.obolibrary.org/obo/GO_0046622 positive regulation of organ growth http://purl.obolibrary.org/obo/GO_0048639 positive regulation of developmental growth Any process that activates or increases the frequency, rate or extent of growth of an organ of an organism. http://purl.obolibrary.org/obo/GO_0046625 sphingolipid binding http://purl.obolibrary.org/obo/GO_0008289 lipid binding Binding to a sphingolipid, a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid). http://purl.obolibrary.org/obo/GO_0046637 regulation of alpha-beta T cell differentiation http://purl.obolibrary.org/obo/GO_0045580 regulation of T cell differentiation Any process that modulates the frequency, rate or extent of alpha-beta T cell differentiation. http://purl.obolibrary.org/obo/GO_0046638 positive regulation of alpha-beta T cell differentiation http://purl.obolibrary.org/obo/GO_0046637 regulation of alpha-beta T cell differentiation Any process that activates or increases the frequency, rate or extent of alpha-beta T cell differentiation. http://purl.obolibrary.org/obo/GO_0046639 negative regulation of alpha-beta T cell differentiation http://purl.obolibrary.org/obo/GO_0046637 regulation of alpha-beta T cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of alpha-beta T cell differentiation. http://purl.obolibrary.org/obo/GO_0046643 regulation of gamma-delta T cell activation http://purl.obolibrary.org/obo/GO_0050863 regulation of T cell activation Any process that modulates the frequency, rate or extent of gamma-delta T cell activation. http://purl.obolibrary.org/obo/GO_0046644 negative regulation of gamma-delta T cell activation http://purl.obolibrary.org/obo/GO_0050868 negative regulation of T cell activation Any process that stops, prevents, or reduces the frequency, rate or extent of gamma-delta T cell activation. http://purl.obolibrary.org/obo/GO_0046645 positive regulation of gamma-delta T cell activation http://purl.obolibrary.org/obo/GO_0046643 regulation of gamma-delta T cell activation Any process that activates or increases the frequency, rate or extent of gamma-delta T cell activation. http://purl.obolibrary.org/obo/GO_0046822 regulation of nucleocytoplasmic transport http://purl.obolibrary.org/obo/GO_0032386 regulation of intracellular transport Any process that modulates the frequency, rate or extent of the directed movement of substances between the nucleus and the cytoplasm. http://purl.obolibrary.org/obo/GO_0046823 negative regulation of nucleocytoplasmic transport http://purl.obolibrary.org/obo/GO_0046822 regulation of nucleocytoplasmic transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances between the cytoplasm and the nucleus. http://purl.obolibrary.org/obo/GO_0046824 positive regulation of nucleocytoplasmic transport http://purl.obolibrary.org/obo/GO_0046822 regulation of nucleocytoplasmic transport Any process that activates or increases the frequency, rate or extent of the directed movement of substances between the nucleus and the cytoplasm. http://purl.obolibrary.org/obo/GO_0046827 positive regulation of protein export from nucleus http://purl.obolibrary.org/obo/GO_0046825 regulation of protein export from nucleus Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the nucleus into the cytoplasm. http://purl.obolibrary.org/obo/GO_0046849 bone remodeling http://purl.obolibrary.org/obo/GO_0048771 tissue remodeling The continuous turnover of bone matrix and mineral that involves first, an increase in resorption (osteoclastic activity) and later, reactive bone formation (osteoblastic activity). The process of bone remodeling takes place in the adult skeleton at discrete foci. The process ensures the mechanical integrity of the skeleton throughout life and plays an important role in calcium homeostasis. An imbalance in the regulation of bone resorption and bone formation results in many of the metabolic bone diseases, such as osteoporosis. http://purl.obolibrary.org/obo/GO_0046850 regulation of bone remodeling http://purl.obolibrary.org/obo/GO_0034103 regulation of tissue remodeling Any process that modulates the frequency, rate or extent of bone remodeling, the processes of bone formation and resorption that combine to maintain skeletal integrity. http://purl.obolibrary.org/obo/GO_0046851 negative regulation of bone remodeling http://purl.obolibrary.org/obo/GO_0046850 regulation of bone remodeling Any process that stops, prevents, or reduces the frequency, rate or extent of bone remodeling. http://purl.obolibrary.org/obo/GO_0046852 positive regulation of bone remodeling http://purl.obolibrary.org/obo/GO_0046850 regulation of bone remodeling Any process that activates or increases the frequency, rate or extent of bone remodeling. http://purl.obolibrary.org/obo/GO_0046865 terpenoid transport http://purl.obolibrary.org/obo/GO_0046864 isoprenoid transport The directed movement of terpenoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Terpenoids are a class of compounds characterized by an isoprenoid chemical structure and include derivatives with various functional groups. http://purl.obolibrary.org/obo/GO_0048103 somatic stem cell division http://purl.obolibrary.org/obo/GO_0017145 stem cell division The self-renewing division of a somatic stem cell, a stem cell that can give rise to cell types of the body other than those of the germ-line. http://purl.obolibrary.org/obo/GO_0048194 Golgi vesicle budding http://purl.obolibrary.org/obo/GO_0006900 vesicle budding from membrane The evagination of the Golgi membrane, resulting in formation of a vesicle. http://purl.obolibrary.org/obo/GO_0048199 vesicle targeting, to, from or within Golgi http://purl.obolibrary.org/obo/GO_0006903 vesicle targeting The process in which vesicles are directed to specific destination membranes during transport to, from or within the Golgi apparatus; mediated by the addition of specific coat proteins, including COPI and COPII proteins and clathrin, to the membrane during vesicle formation. http://purl.obolibrary.org/obo/GO_0048289 isotype switching to IgE isotypes http://purl.obolibrary.org/obo/GO_0045190 isotype switching The switching of activated B cells from IgM biosynthesis to IgE biosynthesis, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and IgE constant region gene segments in the immunoglobulin heavy chain locus. http://purl.obolibrary.org/obo/GO_0048542 lymph gland development http://purl.obolibrary.org/obo/GO_0048534 hematopoietic or lymphoid organ development The process whose specific outcome is the progression of the lymph gland over time, from its formation to the mature structure. The lymph gland is one of the sites of hemocyte differentiation. It consists of three to six bilaterally paired lobes that are attached to the cardioblasts during larval stages, and it degenerates during pupal stages. http://purl.obolibrary.org/obo/GO_0048639 positive regulation of developmental growth http://purl.obolibrary.org/obo/GO_0048638 regulation of developmental growth Any process that activates, maintains or increases the rate of developmental growth. http://purl.obolibrary.org/obo/GO_0048770 pigment granule http://purl.obolibrary.org/obo/GO_0031410 cytoplasmic vesicle A small, subcellular membrane-bounded vesicle containing pigment and/or pigment precursor molecules. Pigment granule biogenesis is poorly understood, as pigment granules are derived from multiple sources including the endoplasmic reticulum, coated vesicles, lysosomes, and endosomes. http://purl.obolibrary.org/obo/GO_0048793 pronephros development http://purl.obolibrary.org/obo/GO_0001822 kidney development The process whose specific outcome is the progression of the pronephros over time, from its formation to the mature structure. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life. http://purl.obolibrary.org/obo/GO_0048799 animal organ maturation http://purl.obolibrary.org/obo/GO_0071695 anatomical structure maturation A developmental process, independent of morphogenetic (shape) change, that is required for an animal organ to attain its fully functional state. An organ is a tissue or set of tissues that work together to perform a specific function or functions. http://purl.obolibrary.org/obo/GO_0048820 hair follicle maturation http://purl.obolibrary.org/obo/GO_0071695 anatomical structure maturation A developmental process, independent of morphogenetic (shape) change, that is required for a hair follicle to attain its fully functional state. http://purl.obolibrary.org/obo/GO_0048821 erythrocyte development http://purl.obolibrary.org/obo/GO_0061515 myeloid cell development The process whose specific outcome is the progression of an erythrocyte over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0048822 enucleate erythrocyte development http://purl.obolibrary.org/obo/GO_0048821 erythrocyte development The process aimed at the progression of an enucleate erythrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. http://purl.obolibrary.org/obo/GO_0048823 nucleate erythrocyte development http://purl.obolibrary.org/obo/GO_0048821 erythrocyte development The process aimed at the progression of a nucleate erythrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. http://purl.obolibrary.org/obo/GO_0048839 inner ear development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the inner ear over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0048844 artery morphogenesis http://purl.obolibrary.org/obo/GO_0048514 blood vessel morphogenesis The process in which the anatomical structures of arterial blood vessels are generated and organized. Arteries are blood vessels that transport blood from the heart to the body and its organs. http://purl.obolibrary.org/obo/GO_0048886 neuromast hair cell differentiation http://purl.obolibrary.org/obo/GO_0042490 mechanoreceptor differentiation The process in which a relatively unspecialized cell acquires specialized features of a neuromast hair cell. Hair cells are the sensory receptors of the neuromast and are located in a portion of the neuromast called the sensory strip. Each hair cell of the neuromast is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. There are approximately seven hair cells within each neuromast, with each hair cell innervated by afferent and efferent neurons. http://purl.obolibrary.org/obo/GO_0048903 anterior lateral line neuromast hair cell differentiation http://purl.obolibrary.org/obo/GO_0048886 neuromast hair cell differentiation The process in which a relatively unspecialized cell acquires specialized features of an anterior lateral line neuromast hair cell. Neuromast hair cells are the sensory receptors of the neuromast and are located in a portion of the neuromast called the sensory strip. Each hair cell of the neuromast is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. There are approximately seven hair cells within each neuromast, with each hair cell innervated by afferent and efferent neurons. http://purl.obolibrary.org/obo/GO_0048923 posterior lateral line neuromast hair cell differentiation http://purl.obolibrary.org/obo/GO_0048886 neuromast hair cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a posterior lateral line neuromast hair cell. (N.B. This may be development of neuromast hair cell type or a set of cell of neuromast hair cell type. This will involve the change of a cell or set of cells from one cell identity to another). Hair cells are the sensory receptors of the neuromast and are located in a portion of the neuromast called the sensory strip. Each hair cell of the neuromast is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. There are approximately seven hair cells within each neuromast, with each hair cell innervated by afferent and efferent neurons. http://purl.obolibrary.org/obo/GO_0050000 chromosome localization http://purl.obolibrary.org/obo/GO_0051640 organelle localization Any process in which a chromosome is transported to, or maintained in, a specific location. http://purl.obolibrary.org/obo/GO_0050746 regulation of lipoprotein metabolic process http://purl.obolibrary.org/obo/GO_0051246 regulation of protein metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving lipoproteins, any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids. http://purl.obolibrary.org/obo/GO_0050748 negative regulation of lipoprotein metabolic process http://purl.obolibrary.org/obo/GO_0050746 regulation of lipoprotein metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving lipoproteins, any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids. http://purl.obolibrary.org/obo/GO_0050772 positive regulation of axonogenesis http://purl.obolibrary.org/obo/GO_0031346 positive regulation of cell projection organization Any process that activates or increases the frequency, rate or extent of axonogenesis. http://purl.obolibrary.org/obo/GO_0050840 extracellular matrix binding http://purl.obolibrary.org/obo/GO_0005488 binding Binding to a component of the extracellular matrix. http://purl.obolibrary.org/obo/GO_0050863 regulation of T cell activation http://purl.obolibrary.org/obo/GO_0051249 regulation of lymphocyte activation Any process that modulates the frequency, rate or extent of T cell activation. http://purl.obolibrary.org/obo/GO_0050868 negative regulation of T cell activation http://purl.obolibrary.org/obo/GO_0050863 regulation of T cell activation Any process that stops, prevents, or reduces the frequency, rate or extent of T cell activation. http://purl.obolibrary.org/obo/GO_0050932 regulation of pigment cell differentiation http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the frequency, rate or extent of pigmented cell differentiation. http://purl.obolibrary.org/obo/GO_0050941 negative regulation of pigment cell differentiation http://purl.obolibrary.org/obo/GO_0050932 regulation of pigment cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of pigment cell differentiation. http://purl.obolibrary.org/obo/GO_0050942 positive regulation of pigment cell differentiation http://purl.obolibrary.org/obo/GO_0045597 positive regulation of cell differentiation Any process that activates or increases the frequency, rate or extent of pigment cell differentiation. http://purl.obolibrary.org/obo/GO_0051098 regulation of binding http://purl.obolibrary.org/obo/GO_0065009 regulation of molecular function Any process that modulates the frequency, rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule. http://purl.obolibrary.org/obo/GO_0051101 regulation of DNA binding http://purl.obolibrary.org/obo/GO_0051098 regulation of binding Any process that modulates the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid). http://purl.obolibrary.org/obo/GO_0051145 smooth muscle cell differentiation http://purl.obolibrary.org/obo/GO_0042692 muscle cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell; smooth muscle lacks transverse striations in its constituent fibers and are almost always involuntary. http://purl.obolibrary.org/obo/GO_0051147 regulation of muscle cell differentiation http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the frequency, rate or extent of muscle cell differentiation. http://purl.obolibrary.org/obo/GO_0051148 negative regulation of muscle cell differentiation http://purl.obolibrary.org/obo/GO_0051147 regulation of muscle cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of muscle cell differentiation. http://purl.obolibrary.org/obo/GO_0051149 positive regulation of muscle cell differentiation http://purl.obolibrary.org/obo/GO_0045597 positive regulation of cell differentiation Any process that activates or increases the frequency, rate or extent of muscle cell differentiation. http://purl.obolibrary.org/obo/GO_0051222 positive regulation of protein transport http://purl.obolibrary.org/obo/GO_0051050 positive regulation of transport Any process that activates or increases the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0051224 negative regulation of protein transport http://purl.obolibrary.org/obo/GO_1903828 negative regulation of protein localization Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0051338 regulation of transferase activity http://purl.obolibrary.org/obo/GO_0050790 regulation of catalytic activity Any process that modulates the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2. http://purl.obolibrary.org/obo/GO_0051402 neuron apoptotic process http://purl.obolibrary.org/obo/GO_0006915 apoptotic process Any apoptotic process in a neuron, the basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system. http://purl.obolibrary.org/obo/GO_0051445 regulation of meiotic cell cycle http://purl.obolibrary.org/obo/GO_2000241 regulation of reproductive process Any process that modulates the rate or extent of progression through the meiotic cell cycle. http://purl.obolibrary.org/obo/GO_0051446 positive regulation of meiotic cell cycle http://purl.obolibrary.org/obo/GO_2000243 positive regulation of reproductive process Any process that activates or increases the frequency, rate or extent of progression through the meiotic cell cycle. http://purl.obolibrary.org/obo/GO_0051447 negative regulation of meiotic cell cycle http://purl.obolibrary.org/obo/GO_2000242 negative regulation of reproductive process Any process that stops, prevents or reduces the rate or extent of progression through the meiotic cell cycle. http://purl.obolibrary.org/obo/GO_0051469 vesicle fusion with vacuole http://purl.obolibrary.org/obo/GO_0097576 vacuole fusion The joining of the lipid bilayer membrane around a vesicle with the lipid bilayer membrane around the vacuole. http://purl.obolibrary.org/obo/GO_0051654 establishment of mitochondrion localization http://purl.obolibrary.org/obo/GO_0051656 establishment of organelle localization The directed movement of the mitochondrion to a specific location. http://purl.obolibrary.org/obo/GO_0051658 maintenance of nucleus location http://purl.obolibrary.org/obo/GO_0051647 nucleus localization Any process in which the nucleus is maintained in a specific location within a cell and prevented from moving elsewhere. http://purl.obolibrary.org/obo/GO_0051890 regulation of cardioblast differentiation http://purl.obolibrary.org/obo/GO_2000736 regulation of stem cell differentiation Any process that modulates the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. http://purl.obolibrary.org/obo/GO_0051930 regulation of sensory perception of pain http://purl.obolibrary.org/obo/GO_0051931 regulation of sensory perception Any process that modulates the frequency, rate or extent of the sensory perception of pain, the series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal. http://purl.obolibrary.org/obo/GO_0051969 regulation of transmission of nerve impulse http://purl.obolibrary.org/obo/GO_0031644 regulation of nervous system process Any process that modulates the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation. http://purl.obolibrary.org/obo/GO_0055059 asymmetric neuroblast division http://purl.obolibrary.org/obo/GO_0055057 neuroblast division The process resulting in the physical partitioning and separation of a neuroblast into two daughter cells with different developmental potentials. http://purl.obolibrary.org/obo/GO_0060065 uterus development http://purl.obolibrary.org/obo/GO_0048608 reproductive structure development The reproductive developmental process whose specific outcome is the progression of the uterus over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0060066 oviduct development http://purl.obolibrary.org/obo/GO_0048608 reproductive structure development The reproductive developmental process whose specific outcome is the progression of an oviduct over time, from its formation to the mature structure. An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism. http://purl.obolibrary.org/obo/GO_0060113 inner ear receptor cell differentiation http://purl.obolibrary.org/obo/GO_0042490 mechanoreceptor differentiation The process in which relatively unspecialized cells, acquire specialized structural and/or functional features of inner ear receptor cells. Inner ear receptor cells are mechanorecptors found in the inner ear responsible for transducing signals involved in balance and sensory perception of sound. http://purl.obolibrary.org/obo/GO_0060173 limb development http://purl.obolibrary.org/obo/GO_0048736 appendage development The process whose specific outcome is the progression of a limb over time, from its formation to the mature structure. A limb is an appendage of an animal used for locomotion or grasping. Examples include legs, arms or some types of fin. http://purl.obolibrary.org/obo/GO_0060174 limb bud formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process pertaining to the initial formation of a limb bud from unspecified parts. This process begins with the formation of a local condensation of mesenchyme cells within the prospective limb field, and ends when a limb bud is recognizable. http://purl.obolibrary.org/obo/GO_0060219 camera-type eye photoreceptor cell differentiation http://purl.obolibrary.org/obo/GO_0001754 eye photoreceptor cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a photoreceptor cell in a camera-type eye. http://purl.obolibrary.org/obo/GO_0060271 cilium assembly http://purl.obolibrary.org/obo/GO_0120031 plasma membrane bounded cell projection assembly The assembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole. http://purl.obolibrary.org/obo/GO_0060348 bone development http://purl.obolibrary.org/obo/GO_0048513 animal organ development The process whose specific outcome is the progression of bone over time, from its formation to the mature structure. Bone is the hard skeletal connective tissue consisting of both mineral and cellular components. http://purl.obolibrary.org/obo/GO_0060359 response to ammonium ion http://purl.obolibrary.org/obo/GO_1901698 response to nitrogen compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ammonium stimulus. http://purl.obolibrary.org/obo/GO_0060465 pharynx development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The biological process whose specific outcome is the progression of a pharynx from an initial condition to its mature state. The pharynx is the part of the digestive system immediately posterior to the mouth. http://purl.obolibrary.org/obo/GO_0060467 negative regulation of fertilization http://purl.obolibrary.org/obo/GO_2000242 negative regulation of reproductive process Any process that decreases the rate, frequency or extent of fertilization. Fertilization is the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy). http://purl.obolibrary.org/obo/GO_0060581 cell fate commitment involved in pattern specification http://purl.obolibrary.org/obo/GO_0045165 cell fate commitment The commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells within a field of cells that will exhibit a certain pattern of differentiation. Positional information is established through protein signals that emanate from a localized source within a developmental field resulting in specification of a cell type. Those signals are then interpreted in a cell-autonomous manner resulting in the determination of the cell type. http://purl.obolibrary.org/obo/GO_0060840 artery development http://purl.obolibrary.org/obo/GO_0001568 blood vessel development The progression of the artery over time, from its initial formation to the mature structure. An artery is a blood vessel that carries blood away from the heart to a capillary bed. http://purl.obolibrary.org/obo/GO_0061005 cell differentiation involved in kidney development http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the kidney as it progresses from its formation to the mature state. http://purl.obolibrary.org/obo/GO_0061009 common bile duct development http://purl.obolibrary.org/obo/GO_0035295 tube development The progression of the common bile duct over time, from its formation to the mature structure. The common bile duct is formed from the joining of the common hepatic duct running from the liver, and the cystic duct running from the gallbladder. The common bile duct transports bile from the liver and gallbladder to the intestine. http://purl.obolibrary.org/obo/GO_0061027 umbilical cord development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the development of the umbilical cord, from its formation to the mature structure. The umbilical cord is an organ or embryonic origin consisting of the 2 umbilical arteries and the one umbilical vein. The umbilical cord connects the cardiovascular system of the fetus to the mother via the placenta. http://purl.obolibrary.org/obo/GO_0061178 regulation of insulin secretion involved in cellular response to glucose stimulus http://purl.obolibrary.org/obo/GO_0060341 regulation of cellular localization Any process that modulates the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose. http://purl.obolibrary.org/obo/GO_0061303 cornea development in camera-type eye http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the cornea over time, from its formation to the mature structure. The cornea is the transparent structure that covers the anterior of the eye. http://purl.obolibrary.org/obo/GO_0061469 regulation of type B pancreatic cell proliferation http://purl.obolibrary.org/obo/GO_0050678 regulation of epithelial cell proliferation Any process that modulates the frequency, rate or extent of type B pancreatic cell proliferation. http://purl.obolibrary.org/obo/GO_0070026 nitric oxide binding http://purl.obolibrary.org/obo/GO_0036094 small molecule binding Binding to nitric oxide (NO). http://purl.obolibrary.org/obo/GO_0070286 axonemal dynein complex assembly http://purl.obolibrary.org/obo/GO_0065003 protein-containing complex assembly The aggregation, arrangement and bonding together of a set of components to form an axonemal dynein complex, a dynein complex found in eukaryotic cilia and flagella, in which the motor domain heads interact with adjacent microtubules to generate a sliding force which is converted to a bending motion. http://purl.obolibrary.org/obo/GO_0070293 renal absorption http://purl.obolibrary.org/obo/GO_0003014 renal system process A renal system process in which water, ions, glucose and proteins are taken up from the collecting ducts, glomerulus and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures (e.g. protein absorption is observed in nephrocytes in Drosophila, see PMID:23264686). http://purl.obolibrary.org/obo/GO_0070295 renal water absorption http://purl.obolibrary.org/obo/GO_0070293 renal absorption A renal system process in which water is taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures. http://purl.obolibrary.org/obo/GO_0070509 calcium ion import http://purl.obolibrary.org/obo/GO_0006816 calcium ion transport The directed movement of calcium ions into a cell or organelle. http://purl.obolibrary.org/obo/GO_0070840 dynein complex binding http://purl.obolibrary.org/obo/GO_0044877 protein-containing complex binding Binding to a dynein complex, a protein complex that contains two or three dynein heavy chains and several light chains, and has microtubule motor activity. http://purl.obolibrary.org/obo/GO_0070874 negative regulation of glycogen metabolic process http://purl.obolibrary.org/obo/GO_0045912 negative regulation of carbohydrate metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving glycogen. http://purl.obolibrary.org/obo/GO_0070875 positive regulation of glycogen metabolic process http://purl.obolibrary.org/obo/GO_0010907 positive regulation of glucose metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving glycogen. http://purl.obolibrary.org/obo/GO_0070977 bone maturation http://purl.obolibrary.org/obo/GO_0048799 animal organ maturation A developmental process, independent of morphogenetic (shape) change, that is required for bone to attain its fully functional state. http://purl.obolibrary.org/obo/GO_0071230 cellular response to amino acid stimulus http://purl.obolibrary.org/obo/GO_0071229 cellular response to acid chemical Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups. http://purl.obolibrary.org/obo/GO_0071242 cellular response to ammonium ion http://purl.obolibrary.org/obo/GO_1901699 cellular response to nitrogen compound Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ammonium stimulus. http://purl.obolibrary.org/obo/GO_0071281 cellular response to iron ion http://purl.obolibrary.org/obo/GO_0010039 response to iron ion Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron ion stimulus. http://purl.obolibrary.org/obo/GO_0071383 cellular response to steroid hormone stimulus http://purl.obolibrary.org/obo/GO_0032870 cellular response to hormone stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a steroid hormone stimulus. http://purl.obolibrary.org/obo/GO_0071385 cellular response to glucocorticoid stimulus http://purl.obolibrary.org/obo/GO_0071384 cellular response to corticosteroid stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucocorticoid stimulus. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects. http://purl.obolibrary.org/obo/GO_0071396 cellular response to lipid http://purl.obolibrary.org/obo/GO_0033993 response to lipid Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid stimulus. http://purl.obolibrary.org/obo/GO_0071418 cellular response to amine stimulus http://purl.obolibrary.org/obo/GO_1901699 cellular response to nitrogen compound Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amine stimulus. An amine is a compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups. http://purl.obolibrary.org/obo/GO_0071462 cellular response to water stimulus http://purl.obolibrary.org/obo/GO_0071229 cellular response to acid chemical Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of water. http://purl.obolibrary.org/obo/GO_0071692 protein localization to extracellular region http://purl.obolibrary.org/obo/GO_0033036 macromolecule localization Any process in which a protein is transported from one specific location in the extracellular region to another, or maintained in a specific extracellular location. http://purl.obolibrary.org/obo/GO_0071711 basement membrane organization http://purl.obolibrary.org/obo/GO_0030198 extracellular matrix organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the basement membrane. http://purl.obolibrary.org/obo/GO_0071731 response to nitric oxide http://purl.obolibrary.org/obo/GO_1901698 response to nitrogen compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitric oxide stimulus. http://purl.obolibrary.org/obo/GO_0071867 response to monoamine http://purl.obolibrary.org/obo/GO_1901698 response to nitrogen compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monoamine stimulus. A monoamine is any of a group of molecular messengers that contain one amino group that is connected to an aromatic ring by ethylene group (-CH2-CH2-). Monoamines are derived from the aromatic amino acids phenylalanine, tyrosine, histidine and tryptophan. http://purl.obolibrary.org/obo/GO_0072014 proximal tubule development http://purl.obolibrary.org/obo/GO_0072080 nephron tubule development The process whose specific outcome is the progression of the proximal tubule over time, from its formation to the mature structure. In mammals, the proximal tubule is a nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle. It has a brush border epithelial morphology. http://purl.obolibrary.org/obo/GO_0072017 distal tubule development http://purl.obolibrary.org/obo/GO_0072080 nephron tubule development The process whose specific outcome is the progression of the distal tubule over time, from its formation to the mature structure. In mammals, the distal tubule is a nephron tubule that begins at the macula densa and extends to the connecting tubule. http://purl.obolibrary.org/obo/GO_0072028 nephron morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structures of the nephron are generated and organized. A nephron is the functional unit of the kidney. http://purl.obolibrary.org/obo/GO_0072078 nephron tubule morphogenesis http://purl.obolibrary.org/obo/GO_0072088 nephron epithelium morphogenesis The process in which the anatomical structures of a nephron tubule are generated and organized. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney. http://purl.obolibrary.org/obo/GO_0072079 nephron tubule formation http://purl.obolibrary.org/obo/GO_0001838 embryonic epithelial tube formation The developmental process pertaining to the initial formation of a nephron tubule from unspecified parts. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney. http://purl.obolibrary.org/obo/GO_0072080 nephron tubule development http://purl.obolibrary.org/obo/GO_0072009 nephron epithelium development The progression of a nephron tubule over time, from its initial formation to the mature structure. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney. http://purl.obolibrary.org/obo/GO_0072102 glomerulus morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structures of the glomerulus are generated and organized. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney. http://purl.obolibrary.org/obo/GO_0072111 cell proliferation involved in kidney development http://purl.obolibrary.org/obo/GO_0008283 cell population proliferation The multiplication or reproduction of cells, resulting in the expansion of the population in the kidney. http://purl.obolibrary.org/obo/GO_0072114 pronephros morphogenesis http://purl.obolibrary.org/obo/GO_0060993 kidney morphogenesis The process in which the anatomical structures of the pronephros are generated and organized. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life. http://purl.obolibrary.org/obo/GO_0072116 pronephros formation http://purl.obolibrary.org/obo/GO_0072003 kidney rudiment formation The developmental process pertaining to the initial formation of the pronephros. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life. http://purl.obolibrary.org/obo/GO_0072156 distal tubule morphogenesis http://purl.obolibrary.org/obo/GO_0072078 nephron tubule morphogenesis The process in which the anatomical structures of a distal tubule are generated and organized. The distal tubule is a nephron tubule that begins at the macula densa and extends to the connecting tubule. http://purl.obolibrary.org/obo/GO_0072158 proximal tubule morphogenesis http://purl.obolibrary.org/obo/GO_0072078 nephron tubule morphogenesis The process in which the anatomical structures of a proximal tubule are generated and organized. The proximal tubule is a nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle. It has a brush border epithelial morphology. http://purl.obolibrary.org/obo/GO_0072160 nephron tubule epithelial cell differentiation http://purl.obolibrary.org/obo/GO_0035850 epithelial cell differentiation involved in kidney development The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the nephron tubule as it progresses from its formation to the mature state. http://purl.obolibrary.org/obo/GO_0072176 nephric duct development http://purl.obolibrary.org/obo/GO_0072073 kidney epithelium development The process whose specific outcome is the progression of a nephric duct over time, from its initial formation to a mature structure. A nephric duct is a tube that drains a primitive kidney. http://purl.obolibrary.org/obo/GO_0072178 nephric duct morphogenesis http://purl.obolibrary.org/obo/GO_0060562 epithelial tube morphogenesis The process in which the anatomical structures of the nephric duct are generated and organized. A nephric duct is a tube that drains a primitive kidney. http://purl.obolibrary.org/obo/GO_0072189 ureter development http://purl.obolibrary.org/obo/GO_0048513 animal organ development The process whose specific outcome is the progression of the ureter over time, from its formation to the mature structure. The ureter is a muscular tube that transports urine from the kidney to the urinary bladder or from the Malpighian tubule to the hindgut. http://purl.obolibrary.org/obo/GO_0072197 ureter morphogenesis http://purl.obolibrary.org/obo/GO_0009887 animal organ morphogenesis The process in which the anatomical structures of the ureter are generated and organized. The ureter is a muscular tube that transports urine from the kidney to the urinary bladder. http://purl.obolibrary.org/obo/GO_0072497 mesenchymal stem cell differentiation http://purl.obolibrary.org/obo/GO_0048863 stem cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal stem cell. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells. http://purl.obolibrary.org/obo/GO_0072537 fibroblast activation http://purl.obolibrary.org/obo/GO_0001775 cell activation A change in the morphology or behavior of a fibroblast resulting from exposure to an activating factor such as a cellular or soluble ligand. http://purl.obolibrary.org/obo/GO_0072595 maintenance of protein localization in organelle http://purl.obolibrary.org/obo/GO_0032507 maintenance of protein location in cell Any process in which a protein is maintained in a specific location a specific location on or in an organelle, and is prevented from moving elsewhere. Encompasses establishment of localization in the membrane or lumen of a membrane-bounded organelle. http://purl.obolibrary.org/obo/GO_0072596 establishment of protein localization to chloroplast http://purl.obolibrary.org/obo/GO_0072594 establishment of protein localization to organelle The directed movement of a protein to a specific location in a chloroplast. http://purl.obolibrary.org/obo/GO_0072657 protein localization to membrane http://purl.obolibrary.org/obo/GO_0051668 localization within membrane A process in which a protein is transported to, or maintained in, a specific location in a membrane. http://purl.obolibrary.org/obo/GO_0072659 protein localization to plasma membrane http://purl.obolibrary.org/obo/GO_1990778 protein localization to cell periphery A process in which a protein is transported to, or maintained in, a specific location in the plasma membrane. http://purl.obolibrary.org/obo/GO_0072697 protein localization to cell cortex http://purl.obolibrary.org/obo/GO_1990778 protein localization to cell periphery A process in which a protein is transported to, or maintained in, the cell cortex. http://purl.obolibrary.org/obo/GO_0072698 protein localization to microtubule cytoskeleton http://purl.obolibrary.org/obo/GO_0044380 protein localization to cytoskeleton A cellular protein localization process in which a protein is transported to, or maintained at, a location within the microtubule cytoskeleton. http://purl.obolibrary.org/obo/GO_0080154 regulation of fertilization http://purl.obolibrary.org/obo/GO_2000241 regulation of reproductive process Any process that modulates the rate, frequency or extent of fertilization. Fertilization is the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy). http://purl.obolibrary.org/obo/GO_0090162 establishment of epithelial cell polarity http://purl.obolibrary.org/obo/GO_0030010 establishment of cell polarity The specification and formation of anisotropic intracellular organization of an epithelial cell. http://purl.obolibrary.org/obo/GO_0090168 Golgi reassembly http://purl.obolibrary.org/obo/GO_0022607 cellular component assembly The reformation of the Golgi following its breakdown and partitioning contributing to Golgi inheritance. http://purl.obolibrary.org/obo/GO_0090276 regulation of peptide hormone secretion http://purl.obolibrary.org/obo/GO_0002791 regulation of peptide secretion Any process that modulates the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules. http://purl.obolibrary.org/obo/GO_0090316 positive regulation of intracellular protein transport http://purl.obolibrary.org/obo/GO_0051222 positive regulation of protein transport Any process that activates or increases the frequency, rate or extent of the directed movement of proteins within cells. http://purl.obolibrary.org/obo/GO_0090317 negative regulation of intracellular protein transport http://purl.obolibrary.org/obo/GO_0051224 negative regulation of protein transport Any process that decreases the frequency, rate or extent of the directed movement of proteins within cells. http://purl.obolibrary.org/obo/GO_0090435 protein localization to nuclear envelope http://purl.obolibrary.org/obo/GO_0034504 protein localization to nucleus A process in which a protein is transported to, or maintained at, a location within a nuclear envelope. http://purl.obolibrary.org/obo/GO_0090497 mesenchymal cell migration http://purl.obolibrary.org/obo/GO_0001667 ameboidal-type cell migration The orderly movement of a mesenchymal cell from one site to another, often during the development of a multicellular organism. http://purl.obolibrary.org/obo/GO_0090596 sensory organ morphogenesis http://purl.obolibrary.org/obo/GO_0009887 animal organ morphogenesis Morphogenesis of a sensory organ. A sensory organ is defined as a tissue or set of tissues that work together to receive and transmit signals from external or internal stimuli. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. http://purl.obolibrary.org/obo/GO_0090598 male anatomical structure morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The processes by which anatomical structures that are only present in the male organism are generated and organized. http://purl.obolibrary.org/obo/GO_0097237 cellular response to toxic substance http://purl.obolibrary.org/obo/GO_0009636 response to toxic substance Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus. http://purl.obolibrary.org/obo/GO_0097355 protein localization to heterochromatin http://purl.obolibrary.org/obo/GO_0071168 protein localization to chromatin Any process in which a protein is transported to, or maintained at, a part of a chromosome that is organized into heterochromatin. http://purl.obolibrary.org/obo/GO_0097576 vacuole fusion http://purl.obolibrary.org/obo/GO_0048284 organelle fusion Merging of two or more vacuoles, or of vacuoles and vesicles within a cell to form a single larger vacuole. http://purl.obolibrary.org/obo/GO_0097648 G protein-coupled receptor complex http://purl.obolibrary.org/obo/GO_0098802 plasma membrane signaling receptor complex A protein complex that contains G protein-coupled receptors. http://purl.obolibrary.org/obo/GO_0097729 9+2 motile cilium http://purl.obolibrary.org/obo/GO_0031514 motile cilium A motile cilium where the axoneme has a ring of nine outer microtubule doublets plus two central microtubules (and is therefore called a 9+2 axoneme). http://purl.obolibrary.org/obo/GO_0098528 skeletal muscle fiber differentiation http://purl.obolibrary.org/obo/GO_0035914 skeletal muscle cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a skeletal muscle fiber cell. Skeletal muscle fiber differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual skeletal muscle fibers fuse to form bigger myotubes and start to contract. http://purl.obolibrary.org/obo/GO_0098751 bone cell development http://purl.obolibrary.org/obo/GO_0048468 cell development The process whose specific outcome is the progression of a bone cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. http://purl.obolibrary.org/obo/GO_0098794 postsynapse http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure The part of a synapse that is part of the post-synaptic cell. http://purl.obolibrary.org/obo/GO_0098840 protein transport along microtubule http://purl.obolibrary.org/obo/GO_0099118 microtubule-based protein transport The directed movement of a protein along a microtubule, mediated by motor proteins. http://purl.obolibrary.org/obo/GO_0099098 microtubule polymerization based movement http://purl.obolibrary.org/obo/GO_0007018 microtubule-based movement The movement of a cellular component as a result of microtubule polymerization. http://purl.obolibrary.org/obo/GO_0099632 protein transport within plasma membrane http://purl.obolibrary.org/obo/GO_0032594 protein transport within lipid bilayer A process in which protein is transported from one region of the plasma membrane to another. http://purl.obolibrary.org/obo/GO_1900116 extracellular negative regulation of signal transduction http://purl.obolibrary.org/obo/GO_1900115 extracellular regulation of signal transduction Any negative regulation of signal transduction that takes place in extracellular region. http://purl.obolibrary.org/obo/GO_1900180 regulation of protein localization to nucleus http://purl.obolibrary.org/obo/GO_0032880 regulation of protein localization Any process that modulates the frequency, rate or extent of protein localization to nucleus. http://purl.obolibrary.org/obo/GO_1900181 negative regulation of protein localization to nucleus http://purl.obolibrary.org/obo/GO_1903828 negative regulation of protein localization Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to nucleus. http://purl.obolibrary.org/obo/GO_1900182 positive regulation of protein localization to nucleus http://purl.obolibrary.org/obo/GO_1903829 positive regulation of protein localization Any process that activates or increases the frequency, rate or extent of protein localization to nucleus. http://purl.obolibrary.org/obo/GO_1901162 primary amino compound biosynthetic process http://purl.obolibrary.org/obo/GO_0009058 biosynthetic process The chemical reactions and pathways resulting in the formation of primary amino compound. http://purl.obolibrary.org/obo/GO_1901338 catecholamine binding http://purl.obolibrary.org/obo/GO_0005488 binding Binding to catecholamine. http://purl.obolibrary.org/obo/GO_1901342 regulation of vasculature development http://purl.obolibrary.org/obo/GO_2000026 regulation of multicellular organismal development Any process that modulates the frequency, rate or extent of vasculature development. http://purl.obolibrary.org/obo/GO_1901655 cellular response to ketone http://purl.obolibrary.org/obo/GO_1901701 cellular response to oxygen-containing compound Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ketone stimulus. http://purl.obolibrary.org/obo/GO_1901699 cellular response to nitrogen compound http://purl.obolibrary.org/obo/GO_1901698 response to nitrogen compound Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen compound stimulus. http://purl.obolibrary.org/obo/GO_1901701 cellular response to oxygen-containing compound http://purl.obolibrary.org/obo/GO_1901700 response to oxygen-containing compound Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen-containing compound stimulus. http://purl.obolibrary.org/obo/GO_1902017 regulation of cilium assembly http://purl.obolibrary.org/obo/GO_0120032 regulation of plasma membrane bounded cell projection assembly Any process that modulates the frequency, rate or extent of cilium assembly. http://purl.obolibrary.org/obo/GO_1902563 regulation of neutrophil activation http://purl.obolibrary.org/obo/GO_0002694 regulation of leukocyte activation Any process that modulates the frequency, rate or extent of neutrophil activation. http://purl.obolibrary.org/obo/GO_1902564 negative regulation of neutrophil activation http://purl.obolibrary.org/obo/GO_1902563 regulation of neutrophil activation Any process that stops, prevents or reduces the frequency, rate or extent of neutrophil activation. http://purl.obolibrary.org/obo/GO_1902565 positive regulation of neutrophil activation http://purl.obolibrary.org/obo/GO_1902563 regulation of neutrophil activation Any process that activates or increases the frequency, rate or extent of neutrophil activation. http://purl.obolibrary.org/obo/GO_1902566 regulation of eosinophil activation http://purl.obolibrary.org/obo/GO_0002694 regulation of leukocyte activation Any process that modulates the frequency, rate or extent of eosinophil activation. http://purl.obolibrary.org/obo/GO_1902567 negative regulation of eosinophil activation http://purl.obolibrary.org/obo/GO_1902566 regulation of eosinophil activation Any process that stops, prevents or reduces the frequency, rate or extent of eosinophil activation. http://purl.obolibrary.org/obo/GO_1902568 positive regulation of eosinophil activation http://purl.obolibrary.org/obo/GO_1902566 regulation of eosinophil activation Any process that activates or increases the frequency, rate or extent of eosinophil activation. http://purl.obolibrary.org/obo/GO_1902913 positive regulation of neuroepithelial cell differentiation http://purl.obolibrary.org/obo/GO_0030858 positive regulation of epithelial cell differentiation Any process that activates or increases the frequency, rate or extent of neuroepithelial cell differentiation. http://purl.obolibrary.org/obo/GO_1903119 protein localization to actin cytoskeleton http://purl.obolibrary.org/obo/GO_0044380 protein localization to cytoskeleton A process in which a protein is transported to, or maintained in, the location of an actin cytoskeleton. http://purl.obolibrary.org/obo/GO_1903224 regulation of endodermal cell differentiation http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the frequency, rate or extent of endodermal cell differentiation. http://purl.obolibrary.org/obo/GO_1903225 negative regulation of endodermal cell differentiation http://purl.obolibrary.org/obo/GO_1903224 regulation of endodermal cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of endodermal cell differentiation. http://purl.obolibrary.org/obo/GO_1903306 negative regulation of regulated secretory pathway http://purl.obolibrary.org/obo/GO_1903305 regulation of regulated secretory pathway Any process that stops, prevents or reduces the frequency, rate or extent of regulated secretory pathway. http://purl.obolibrary.org/obo/GO_1903307 positive regulation of regulated secretory pathway http://purl.obolibrary.org/obo/GO_1903305 regulation of regulated secretory pathway Any process that activates or increases the frequency, rate or extent of regulated secretory pathway. http://purl.obolibrary.org/obo/GO_1903706 regulation of hemopoiesis http://purl.obolibrary.org/obo/GO_0060284 regulation of cell development Any process that modulates the frequency, rate or extent of hemopoiesis. http://purl.obolibrary.org/obo/GO_1903707 negative regulation of hemopoiesis http://purl.obolibrary.org/obo/GO_0010721 negative regulation of cell development Any process that stops, prevents or reduces the frequency, rate or extent of hemopoiesis. http://purl.obolibrary.org/obo/GO_1903708 positive regulation of hemopoiesis http://purl.obolibrary.org/obo/GO_0010720 positive regulation of cell development Any process that activates or increases the frequency, rate or extent of hemopoiesis. http://purl.obolibrary.org/obo/GO_1903729 regulation of plasma membrane organization http://purl.obolibrary.org/obo/GO_0051128 regulation of cellular component organization Any process that modulates the frequency, rate or extent of plasma membrane organization. http://purl.obolibrary.org/obo/GO_1903778 protein localization to vacuolar membrane http://purl.obolibrary.org/obo/GO_0072665 protein localization to vacuole A process in which a protein is transported to, or maintained in, a location within a vacuolar membrane. http://purl.obolibrary.org/obo/GO_1904018 positive regulation of vasculature development http://purl.obolibrary.org/obo/GO_1901342 regulation of vasculature development Any process that activates or increases the frequency, rate or extent of vasculature development. http://purl.obolibrary.org/obo/GO_1904063 negative regulation of cation transmembrane transport http://purl.obolibrary.org/obo/GO_1904062 regulation of monoatomic cation transmembrane transport Any process that stops, prevents or reduces the frequency, rate or extent of cation transmembrane transport. http://purl.obolibrary.org/obo/GO_1904064 positive regulation of cation transmembrane transport http://purl.obolibrary.org/obo/GO_1904062 regulation of monoatomic cation transmembrane transport Any process that activates or increases the frequency, rate or extent of cation transmembrane transport. http://purl.obolibrary.org/obo/GO_1905156 negative regulation of photosynthesis http://purl.obolibrary.org/obo/GO_0010109 regulation of photosynthesis Any process that stops, prevents or reduces the frequency, rate or extent of photosynthesis. http://purl.obolibrary.org/obo/GO_1905515 non-motile cilium assembly http://purl.obolibrary.org/obo/GO_0060271 cilium assembly The aggregation, arrangement and bonding together of a set of components to form a non-motile cilium. http://purl.obolibrary.org/obo/GO_1905690 nucleus disassembly http://purl.obolibrary.org/obo/GO_1903008 organelle disassembly The disaggregation of a nucleus into its constituent components. http://purl.obolibrary.org/obo/GO_1905770 regulation of mesodermal cell differentiation http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the frequency, rate or extent of mesodermal cell differentiation. http://purl.obolibrary.org/obo/GO_1905771 negative regulation of mesodermal cell differentiation http://purl.obolibrary.org/obo/GO_1905770 regulation of mesodermal cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of mesodermal cell differentiation. http://purl.obolibrary.org/obo/GO_1990777 lipoprotein particle http://purl.obolibrary.org/obo/GO_0032994 protein-lipid complex A spherical particle containing non-covalently associated proteins and lipids. Examples are plasma lipoprotein particles which transport lipids in the blood or lymph. http://purl.obolibrary.org/obo/GO_1990778 protein localization to cell periphery http://purl.obolibrary.org/obo/GO_0008104 intracellular protein localization A process in which a protein is transported to, or maintained in, the cell periphery. http://purl.obolibrary.org/obo/GO_2000355 negative regulation of ovarian follicle development http://purl.obolibrary.org/obo/GO_2000354 regulation of ovarian follicle development Any process that stops, prevents or reduces the frequency, rate or extent of ovarian follicle development. http://purl.obolibrary.org/obo/GO_2000383 regulation of ectoderm development http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of ectoderm development. http://purl.obolibrary.org/obo/GO_2000384 negative regulation of ectoderm development http://purl.obolibrary.org/obo/GO_2000383 regulation of ectoderm development Any process that stops, prevents or reduces the frequency, rate or extent of ectoderm development. http://purl.obolibrary.org/obo/GO_2000387 regulation of antral ovarian follicle growth http://purl.obolibrary.org/obo/GO_2000241 regulation of reproductive process Any process that modulates the frequency, rate or extent of antral ovarian follicle growth. http://purl.obolibrary.org/obo/GO_2000388 positive regulation of antral ovarian follicle growth http://purl.obolibrary.org/obo/GO_2000243 positive regulation of reproductive process Any process that activates or increases the frequency, rate or extent of antral ovarian follicle growth. http://purl.obolibrary.org/obo/GO_2000514 regulation of CD4-positive, alpha-beta T cell activation http://purl.obolibrary.org/obo/GO_0046634 regulation of alpha-beta T cell activation Any process that modulates the frequency, rate or extent of CD4-positive, alpha-beta T cell activation. http://purl.obolibrary.org/obo/GO_2000515 negative regulation of CD4-positive, alpha-beta T cell activation http://purl.obolibrary.org/obo/GO_2000514 regulation of CD4-positive, alpha-beta T cell activation Any process that stops, prevents or reduces the frequency, rate or extent of CD4-positive, alpha-beta T cell activation. http://purl.obolibrary.org/obo/GO_2000516 positive regulation of CD4-positive, alpha-beta T cell activation http://purl.obolibrary.org/obo/GO_2000514 regulation of CD4-positive, alpha-beta T cell activation Any process that activates or increases the frequency, rate or extent of CD4-positive, alpha-beta T cell activation. http://purl.obolibrary.org/obo/GO_2000542 negative regulation of gastrulation http://purl.obolibrary.org/obo/GO_0010470 regulation of gastrulation Any process that stops, prevents or reduces the frequency, rate or extent of gastrulation. http://purl.obolibrary.org/obo/GO_2000881 regulation of starch catabolic process http://purl.obolibrary.org/obo/GO_2000904 regulation of starch metabolic process Any process that modulates the frequency, rate or extent of starch catabolic process. http://purl.obolibrary.org/obo/GO_2000883 positive regulation of starch catabolic process http://purl.obolibrary.org/obo/GO_0045913 positive regulation of carbohydrate metabolic process Any process that activates or increases the frequency, rate or extent of starch catabolic process. http://purl.obolibrary.org/obo/GO_2000980 regulation of inner ear receptor cell differentiation http://purl.obolibrary.org/obo/GO_0045631 regulation of mechanoreceptor differentiation Any process that modulates the frequency, rate or extent of inner ear receptor cell differentiation. http://purl.obolibrary.org/obo/GO_2000981 negative regulation of inner ear receptor cell differentiation http://purl.obolibrary.org/obo/GO_2000980 regulation of inner ear receptor cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of inner ear receptor cell differentiation. http://purl.obolibrary.org/obo/GO_2000982 positive regulation of inner ear receptor cell differentiation http://purl.obolibrary.org/obo/GO_2000980 regulation of inner ear receptor cell differentiation Any process that activates or increases the frequency, rate or extent of inner ear receptor cell differentiation. http://purl.obolibrary.org/obo/GO_2001028 positive regulation of endothelial cell chemotaxis http://purl.obolibrary.org/obo/GO_0010595 positive regulation of endothelial cell migration Any process that activates or increases the frequency, rate or extent of endothelial cell chemotaxis. http://purl.obolibrary.org/obo/GO_2001057 reactive nitrogen species metabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process The chemical reactions and pathways involving a reactive nitrogen species. http://purl.obolibrary.org/obo/GO_2001185 regulation of CD8-positive, alpha-beta T cell activation http://purl.obolibrary.org/obo/GO_0046634 regulation of alpha-beta T cell activation Any process that modulates the frequency, rate or extent of CD8-positive, alpha-beta T cell activation. http://purl.obolibrary.org/obo/GO_2001186 negative regulation of CD8-positive, alpha-beta T cell activation http://purl.obolibrary.org/obo/GO_2001185 regulation of CD8-positive, alpha-beta T cell activation Any process that stops, prevents or reduces the frequency, rate or extent of CD8-positive, alpha-beta T cell activation. http://purl.obolibrary.org/obo/GO_2001187 positive regulation of CD8-positive, alpha-beta T cell activation http://purl.obolibrary.org/obo/GO_2001185 regulation of CD8-positive, alpha-beta T cell activation Any process that activates or increases the frequency, rate or extent of CD8-positive, alpha-beta T cell activation. http://purl.obolibrary.org/obo/GO_0080164 regulation of nitric oxide metabolic process http://purl.obolibrary.org/obo/GO_0019222 regulation of metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water. http://purl.obolibrary.org/obo/GO_0086001 cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_0001508 action potential An action potential that occurs in a cardiac muscle cell. http://purl.obolibrary.org/obo/GO_0086002 cardiac muscle cell action potential involved in contraction http://purl.obolibrary.org/obo/GO_0086001 cardiac muscle cell action potential An action potential that occurs in a cardiac muscle cell and is involved in its contraction. http://purl.obolibrary.org/obo/GO_0086003 cardiac muscle cell contraction http://purl.obolibrary.org/obo/GO_0070252 actin-mediated cell contraction The actin filament-based process in which cytoplasmic actin filaments slide past one another resulting in contraction of a cardiac muscle cell. http://purl.obolibrary.org/obo/GO_0086004 regulation of cardiac muscle cell contraction http://purl.obolibrary.org/obo/GO_0055117 regulation of cardiac muscle contraction Any process that modulates the frequency, rate or extent of cardiac muscle cell contraction. http://purl.obolibrary.org/obo/GO_0086005 ventricular cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_0086002 cardiac muscle cell action potential involved in contraction An action potential that occurs in a ventricular cardiac muscle cell. http://purl.obolibrary.org/obo/GO_0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_0005248 voltage-gated sodium channel activity Enables the transmembrane transfer of a sodium ion by a voltage-gated channel through the plasma membrane of a cardiac muscle cell contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. http://purl.obolibrary.org/obo/GO_0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_0005245 voltage-gated calcium channel activity Enables the transmembrane transfer of a calcium ion by a voltage-gated channel across the plasma membrane of a cardiac muscle cell that contributes to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. http://purl.obolibrary.org/obo/GO_0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization http://purl.obolibrary.org/obo/GO_0005249 voltage-gated potassium channel activity Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of a cardiac muscle cell contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. http://purl.obolibrary.org/obo/GO_0086010 membrane depolarization during action potential http://purl.obolibrary.org/obo/GO_0051899 membrane depolarization The process in which membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential. http://purl.obolibrary.org/obo/GO_0086011 membrane repolarization during action potential http://purl.obolibrary.org/obo/GO_0086009 membrane repolarization The process in which ions are transported across a membrane such that the membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential. http://purl.obolibrary.org/obo/GO_0086012 membrane depolarization during cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_0086010 membrane depolarization during action potential The process in which cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential. http://purl.obolibrary.org/obo/GO_0086013 membrane repolarization during cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_0099622 cardiac muscle cell membrane repolarization The process in which ions are transported across a membrane such that the cardiac muscle cell plasma membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential. http://purl.obolibrary.org/obo/GO_0086014 atrial cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_0086002 cardiac muscle cell action potential involved in contraction An action potential that occurs in an atrial cardiac muscle cell. http://purl.obolibrary.org/obo/GO_0086015 SA node cell action potential http://purl.obolibrary.org/obo/GO_0086001 cardiac muscle cell action potential An action potential that occurs in a sinoatrial node cardiac muscle cell. http://purl.obolibrary.org/obo/GO_0086016 AV node cell action potential http://purl.obolibrary.org/obo/GO_0086001 cardiac muscle cell action potential An action potential that occurs in an atrioventricular node cardiac muscle cell. http://purl.obolibrary.org/obo/GO_0086017 Purkinje myocyte action potential http://purl.obolibrary.org/obo/GO_0086001 cardiac muscle cell action potential An action potential that occurs in a Purkinje myocyte. http://purl.obolibrary.org/obo/GO_0086018 SA node cell to atrial cardiac muscle cell signaling http://purl.obolibrary.org/obo/GO_0086070 SA node cell to atrial cardiac muscle cell communication Any process that mediates the transfer of information from an SA node cardiomyocyte to an atrial cardiomyocyte. http://purl.obolibrary.org/obo/GO_0086026 atrial cardiac muscle cell to AV node cell signaling http://purl.obolibrary.org/obo/GO_0086066 atrial cardiac muscle cell to AV node cell communication Any process that mediates the transfer of information from an atrial cardiomyocyte to an AV node cell. http://purl.obolibrary.org/obo/GO_0086027 AV node cell to bundle of His cell signaling http://purl.obolibrary.org/obo/GO_0086067 AV node cell to bundle of His cell communication Any process that mediates the transfer of information from an AV node cardiac muscle cell to a bundle of His cardiomyocyte. http://purl.obolibrary.org/obo/GO_0086028 bundle of His cell to Purkinje myocyte signaling http://purl.obolibrary.org/obo/GO_0086069 bundle of His cell to Purkinje myocyte communication Any process that mediates the transfer of information from a bundle of His cardiomyocyte to a Purkinje myocyte. http://purl.obolibrary.org/obo/GO_0086029 Purkinje myocyte to ventricular cardiac muscle cell signaling http://purl.obolibrary.org/obo/GO_0086068 Purkinje myocyte to ventricular cardiac muscle cell communication Any process that mediates the transfer of information from a Purkinje myocyte to a ventricular cardiac muscle cell. http://purl.obolibrary.org/obo/GO_0086041 voltage-gated potassium channel activity involved in SA node cell action potential depolarization http://purl.obolibrary.org/obo/GO_0005249 voltage-gated potassium channel activity Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of an SA node cardiac muscle cell contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. http://purl.obolibrary.org/obo/GO_0086043 bundle of His cell action potential http://purl.obolibrary.org/obo/GO_0086001 cardiac muscle cell action potential An action potential that occurs in a bundle of His cell. http://purl.obolibrary.org/obo/GO_0086045 membrane depolarization during AV node cell action potential http://purl.obolibrary.org/obo/GO_0086012 membrane depolarization during cardiac muscle cell action potential The process in which AV node cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential. http://purl.obolibrary.org/obo/GO_0086046 membrane depolarization during SA node cell action potential http://purl.obolibrary.org/obo/GO_0086012 membrane depolarization during cardiac muscle cell action potential The process in which SA node cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential. http://purl.obolibrary.org/obo/GO_0086047 membrane depolarization during Purkinje myocyte cell action potential http://purl.obolibrary.org/obo/GO_0086012 membrane depolarization during cardiac muscle cell action potential The process in which Purkinje myocyte membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential. http://purl.obolibrary.org/obo/GO_0086048 membrane depolarization during bundle of His cell action potential http://purl.obolibrary.org/obo/GO_0086012 membrane depolarization during cardiac muscle cell action potential The process in which bundle of His cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential. http://purl.obolibrary.org/obo/GO_0086049 membrane repolarization during AV node cell action potential http://purl.obolibrary.org/obo/GO_0086013 membrane repolarization during cardiac muscle cell action potential The process in which ions are transported across a membrane such that the AV node cardiac muscle cell membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential. http://purl.obolibrary.org/obo/GO_0086050 membrane repolarization during bundle of His cell action potential http://purl.obolibrary.org/obo/GO_0086013 membrane repolarization during cardiac muscle cell action potential The process in which ions are transported across a membrane such that the bundle of His cardiac muscle cell membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential. http://purl.obolibrary.org/obo/GO_0086051 membrane repolarization during Purkinje myocyte action potential http://purl.obolibrary.org/obo/GO_0086013 membrane repolarization during cardiac muscle cell action potential The process in which ions are transported across a membrane such that the Purkinje myocyte membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential. http://purl.obolibrary.org/obo/GO_0086052 membrane repolarization during SA node cell action potential http://purl.obolibrary.org/obo/GO_0086013 membrane repolarization during cardiac muscle cell action potential The process in which an SA node cardiac muscle cell membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential. http://purl.obolibrary.org/obo/GO_0086056 voltage-gated calcium channel activity involved in AV node cell action potential http://purl.obolibrary.org/obo/GO_0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential Enables the transmembrane transfer of a calcium ion by a voltage-gated channel across the plasma membrane of an AV node cardiac muscle cell that contributes to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. http://purl.obolibrary.org/obo/GO_0086057 voltage-gated calcium channel activity involved in bundle of His cell action potential http://purl.obolibrary.org/obo/GO_0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential Enables the transmembrane transfer of a calcium ion by a voltage-gated channel across the plasma membrane of a bundle of His cardiac muscle cell that contributes to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. http://purl.obolibrary.org/obo/GO_0086059 voltage-gated calcium channel activity involved SA node cell action potential http://purl.obolibrary.org/obo/GO_0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential Enables the transmembrane transfer of a calcium ion by a voltage-gated channel across the plasma membrane of an SA node cardiac muscle cell that contributes to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. http://purl.obolibrary.org/obo/GO_0086060 voltage-gated sodium channel activity involved in AV node cell action potential http://purl.obolibrary.org/obo/GO_0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential Enables the transmembrane transfer of a sodium ion by a voltage-gated channel through the plasma membrane of an AV node cardiac muscle cell contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. http://purl.obolibrary.org/obo/GO_0086061 voltage-gated sodium channel activity involved in bundle of His cell action potential http://purl.obolibrary.org/obo/GO_0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential Enables the transmembrane transfer of a sodium ion by a voltage-gated channel through the plasma membrane of a bundle of His cardiac muscle cell contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. http://purl.obolibrary.org/obo/GO_0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential http://purl.obolibrary.org/obo/GO_0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential Enables the transmembrane transfer of a sodium ion by a voltage-gated channel through the plasma membrane of a Purkinje myocyte contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. http://purl.obolibrary.org/obo/GO_0086063 voltage-gated sodium channel activity involved in SA node cell action potential http://purl.obolibrary.org/obo/GO_0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential Enables the transmembrane transfer of a sodium ion by a voltage-gated channel through the plasma membrane of an SA node cardiac muscle cell contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. http://purl.obolibrary.org/obo/GO_0086065 cell communication involved in cardiac conduction http://purl.obolibrary.org/obo/GO_0007154 cell communication Any process that mediates interactions between a cell and its surroundings that contributes to the process of cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. http://purl.obolibrary.org/obo/GO_0086066 atrial cardiac muscle cell to AV node cell communication http://purl.obolibrary.org/obo/GO_0086065 cell communication involved in cardiac conduction The process that mediates interactions between an atrial cardiomyocyte and its surroundings that contributes to the process of the atrial cardiomyocyte communicating with an AV node cell in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. http://purl.obolibrary.org/obo/GO_0086067 AV node cell to bundle of His cell communication http://purl.obolibrary.org/obo/GO_0086065 cell communication involved in cardiac conduction The process that mediates interactions between an AV node cell and its surroundings that contributes to the process of the AV node cell communicating with a bundle of His cell in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. http://purl.obolibrary.org/obo/GO_0086068 Purkinje myocyte to ventricular cardiac muscle cell communication http://purl.obolibrary.org/obo/GO_0086065 cell communication involved in cardiac conduction The process that mediates interactions between a Purkinje myocyte and its surroundings that contributes to the process of the Purkinje myocyte communicating with a ventricular cardiac muscle cell in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. http://purl.obolibrary.org/obo/GO_0086069 bundle of His cell to Purkinje myocyte communication http://purl.obolibrary.org/obo/GO_0086065 cell communication involved in cardiac conduction The process that mediates interactions between a bundle of His cell and its surroundings that contributes to the process of the bundle of His cell communicating with a Purkinje myocyte in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. http://purl.obolibrary.org/obo/GO_0086070 SA node cell to atrial cardiac muscle cell communication http://purl.obolibrary.org/obo/GO_0086065 cell communication involved in cardiac conduction The process that mediates interactions between an SA node cardiomyocyte and its surroundings that contributes to the process of the SA node cardiomyocyte communicating with an atrial cardiomyocyte in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. http://purl.obolibrary.org/obo/GO_0086087 voltage-gated potassium channel activity involved in bundle of His cell action potential repolarization http://purl.obolibrary.org/obo/GO_0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of a bundle of His cell contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. http://purl.obolibrary.org/obo/GO_0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization http://purl.obolibrary.org/obo/GO_0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of an atrial cardiomyocyte contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. http://purl.obolibrary.org/obo/GO_0086090 voltage-gated potassium channel activity involved in SA node cell action potential repolarization http://purl.obolibrary.org/obo/GO_0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of an SA node cell contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. http://purl.obolibrary.org/obo/GO_0086103 G protein-coupled receptor signaling pathway involved in heart process http://purl.obolibrary.org/obo/GO_0007186 G protein-coupled receptor signaling pathway An G protein-coupled receptor signaling pathway which contributes to a circulatory system process carried out by the heart. http://purl.obolibrary.org/obo/GO_0089704 L-glutamate transmembrane export from vacuole http://purl.obolibrary.org/obo/GO_0032974 amino acid transmembrane export from vacuole The directed movement of L-glutamate out of the vacuole, across the vacuolar membrane. http://purl.obolibrary.org/obo/GO_0089708 L-histidine transmembrane export from vacuole http://purl.obolibrary.org/obo/GO_1902024 L-histidine transport The directed movement of L-histidine out of the vacuole, across the vacuolar membrane. http://purl.obolibrary.org/obo/GO_0089718 amino acid import across plasma membrane http://purl.obolibrary.org/obo/GO_0098739 import across plasma membrane The directed movement of an amino acid from outside of a cell, across the plasma membrane and into the cytosol. http://purl.obolibrary.org/obo/GO_0090009 primitive streak formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The developmental process pertaining to the initial formation of the primitive streak from unspecified parts. The primitive streak is a ridge of cells running along the midline of the embryo where the mesoderm ingresses. It defines the anterior-posterior axis. http://purl.obolibrary.org/obo/GO_0090022 regulation of neutrophil chemotaxis http://purl.obolibrary.org/obo/GO_0071622 regulation of granulocyte chemotaxis Any process that modulates the frequency, rate, or extent of neutrophil chemotaxis. Neutrophil chemotaxis is the directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding. http://purl.obolibrary.org/obo/GO_0090023 positive regulation of neutrophil chemotaxis http://purl.obolibrary.org/obo/GO_0071624 positive regulation of granulocyte chemotaxis Any process that increases the frequency, rate, or extent of neutrophil chemotaxis. Neutrophil chemotaxis is the directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding. http://purl.obolibrary.org/obo/GO_0090024 negative regulation of neutrophil chemotaxis http://purl.obolibrary.org/obo/GO_0071623 negative regulation of granulocyte chemotaxis Any process that decreases the frequency, rate, or extent of neutrophil chemotaxis. Neutrophil chemotaxis is the directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding. http://purl.obolibrary.org/obo/GO_0090025 regulation of monocyte chemotaxis http://purl.obolibrary.org/obo/GO_0071675 regulation of mononuclear cell migration Any process that modulates the frequency, rate, or extent of monocyte chemotaxis. http://purl.obolibrary.org/obo/GO_0090026 positive regulation of monocyte chemotaxis http://purl.obolibrary.org/obo/GO_0071677 positive regulation of mononuclear cell migration Any process that increases the frequency, rate, or extent of monocyte chemotaxis. http://purl.obolibrary.org/obo/GO_0090027 negative regulation of monocyte chemotaxis http://purl.obolibrary.org/obo/GO_0071676 negative regulation of mononuclear cell migration Any process that decreases the frequency, rate, or extent of monocyte chemotaxis. http://purl.obolibrary.org/obo/GO_0090063 positive regulation of microtubule nucleation http://purl.obolibrary.org/obo/GO_0010968 regulation of microtubule nucleation Any process that increases the rate, frequency or extent of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell. http://purl.obolibrary.org/obo/GO_0090069 regulation of ribosome biogenesis http://purl.obolibrary.org/obo/GO_0044087 regulation of cellular component biogenesis Any process that modulates the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits. http://purl.obolibrary.org/obo/GO_0090070 positive regulation of ribosome biogenesis http://purl.obolibrary.org/obo/GO_0044089 positive regulation of cellular component biogenesis Any process that increases the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits. http://purl.obolibrary.org/obo/GO_0090071 negative regulation of ribosome biogenesis http://purl.obolibrary.org/obo/GO_0090069 regulation of ribosome biogenesis Any process that decreases the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits. http://purl.obolibrary.org/obo/GO_0090078 smooth muscle derived foam cell differentiation http://purl.obolibrary.org/obo/GO_0090077 foam cell differentiation The process in which a smooth muscle cell acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions. http://purl.obolibrary.org/obo/GO_0090091 positive regulation of extracellular matrix disassembly http://purl.obolibrary.org/obo/GO_0010715 regulation of extracellular matrix disassembly Any process that increases the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix. http://purl.obolibrary.org/obo/GO_0090102 cochlea development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the cochlea over time from its formation to the mature structure. The cochlea is the snail-shaped portion of the inner ear that is responsible for the detection of sound. http://purl.obolibrary.org/obo/GO_0090103 cochlea morphogenesis http://purl.obolibrary.org/obo/GO_0048598 embryonic morphogenesis The process in which the cochlea is generated and organized. http://purl.obolibrary.org/obo/GO_0090104 pancreatic epsilon cell differentiation http://purl.obolibrary.org/obo/GO_0035883 enteroendocrine cell differentiation The process in which relatively unspecialized cells acquire specialized structural and functional features of a pancreatic epsilon cell. A pancreatic epsilon cell is a cell in the pancreas that secretes ghrelin. http://purl.obolibrary.org/obo/GO_0090105 pancreatic E cell development http://purl.obolibrary.org/obo/GO_0002064 epithelial cell development The process whose specific outcome is the progression of a pancreatic E cell over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0090138 regulation of actin cytoskeleton organization by cell-cell adhesion http://purl.obolibrary.org/obo/GO_0098609 cell-cell adhesion Any cell-cell adhesion process that modulates the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins. http://purl.obolibrary.org/obo/GO_0090139 mitochondrial chromosome packaging http://purl.obolibrary.org/obo/GO_0051276 chromosome organization A process in which mitochondrial chromosomal DNA and associated proteins organize into a compact, orderly structure. http://purl.obolibrary.org/obo/GO_0090140 regulation of mitochondrial fission http://purl.obolibrary.org/obo/GO_0010821 regulation of mitochondrion organization Any process that modulates the rate, frequency or extent of mitochondrial fission. Mitochondrial fission is the division of a mitochondrion within a cell to form two or more separate mitochondrial compartments. http://purl.obolibrary.org/obo/GO_0090141 positive regulation of mitochondrial fission http://purl.obolibrary.org/obo/GO_0010638 positive regulation of organelle organization Any process that increases the rate, frequency or extent of mitochondrial fission. Mitochondrial fission is the division of a mitochondrion within a cell to form two or more separate mitochondrial compartments. http://purl.obolibrary.org/obo/GO_0090153 regulation of sphingolipid biosynthetic process http://purl.obolibrary.org/obo/GO_0010556 regulation of macromolecule biosynthetic process Any process that modulates the rate, frequency or extent of sphingolipid biosynthesis. Sphingolipid biosynthesis is the chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid). http://purl.obolibrary.org/obo/GO_0090154 positive regulation of sphingolipid biosynthetic process http://purl.obolibrary.org/obo/GO_0046889 positive regulation of lipid biosynthetic process Any process that increases the rate, frequency or extent of sphingolipid biosynthesis. Sphingolipid biosynthesis is the chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid). http://purl.obolibrary.org/obo/GO_0090155 negative regulation of sphingolipid biosynthetic process http://purl.obolibrary.org/obo/GO_0051055 negative regulation of lipid biosynthetic process Any process that decreases the rate, frequency or extent of sphingolipid biosynthesis. Sphingolipid biosynthesis is the chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid). http://purl.obolibrary.org/obo/GO_0090156 intracellular sphingolipid homeostasis http://purl.obolibrary.org/obo/GO_0055088 lipid homeostasis A homeostatic process involved in the maintenance of a steady state level of sphingolipids within a cell. http://purl.obolibrary.org/obo/GO_0090160 Golgi to lysosome transport http://purl.obolibrary.org/obo/GO_0016482 cytosolic transport The directed movement of substances from the Golgi to lysosomes. http://purl.obolibrary.org/obo/GO_0090166 Golgi disassembly http://purl.obolibrary.org/obo/GO_1903008 organelle disassembly A cellular process that results in the breakdown of a Golgi apparatus that contributes to Golgi inheritance. http://purl.obolibrary.org/obo/GO_0090170 regulation of Golgi inheritance http://purl.obolibrary.org/obo/GO_1903358 regulation of Golgi organization Any process that modulates the rate, frequency or extent of Golgi inheritance. Golgi inheritance is the partitioning of Golgi apparatus between daughter cells at cell division. http://purl.obolibrary.org/obo/GO_0090190 positive regulation of branching involved in ureteric bud morphogenesis http://purl.obolibrary.org/obo/GO_0090189 regulation of branching involved in ureteric bud morphogenesis Any process that increases the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules. http://purl.obolibrary.org/obo/GO_0090258 negative regulation of mitochondrial fission http://purl.obolibrary.org/obo/GO_0010639 negative regulation of organelle organization Any process that decreases the rate, frequency or extent of mitochondrial fission. Mitochondrial fission is the division of a mitochondrion within a cell to form two or more separate mitochondrial compartments. http://purl.obolibrary.org/obo/GO_0090273 regulation of somatostatin secretion http://purl.obolibrary.org/obo/GO_0090276 regulation of peptide hormone secretion Any process that modulates the rate, frequency, extent of the regulated release of somatostatin from secretory granules in the D cells of the pancreas. http://purl.obolibrary.org/obo/GO_0090274 positive regulation of somatostatin secretion http://purl.obolibrary.org/obo/GO_0090273 regulation of somatostatin secretion Any process that increases the rate, frequency, extent of the regulated release of somatostatin from secretory granules in the D cells of the pancreas. http://purl.obolibrary.org/obo/GO_0090275 negative regulation of somatostatin secretion http://purl.obolibrary.org/obo/GO_0090273 regulation of somatostatin secretion Any process that decreases the rate, frequency, extent of the regulated release of somatostatin from secretory granules in the D cells of the pancreas. http://purl.obolibrary.org/obo/GO_0090289 regulation of osteoclast proliferation http://purl.obolibrary.org/obo/GO_0070663 regulation of leukocyte proliferation Any process that modulates the rate, frequency, or extent of the multiplication or reproduction of osteoclasts, resulting in the expansion of an osteoclast cell population. http://purl.obolibrary.org/obo/GO_0090290 positive regulation of osteoclast proliferation http://purl.obolibrary.org/obo/GO_0090289 regulation of osteoclast proliferation Any process that increases the rate, frequency, or extent of the multiplication or reproduction of osteoclasts, resulting in the expansion of an osteoclast cell population. http://purl.obolibrary.org/obo/GO_0090291 negative regulation of osteoclast proliferation http://purl.obolibrary.org/obo/GO_0090289 regulation of osteoclast proliferation Any process that decreases the rate, frequency, or extent of the multiplication or reproduction of osteoclasts, resulting in the expansion of an osteoclast cell population. http://purl.obolibrary.org/obo/GO_0090299 regulation of neural crest formation http://purl.obolibrary.org/obo/GO_0010717 regulation of epithelial to mesenchymal transition Any process that modulates the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation proceeds. http://purl.obolibrary.org/obo/GO_0090300 positive regulation of neural crest formation http://purl.obolibrary.org/obo/GO_0010718 positive regulation of epithelial to mesenchymal transition Any process that increases the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation proceeds. http://purl.obolibrary.org/obo/GO_0090301 negative regulation of neural crest formation http://purl.obolibrary.org/obo/GO_0010719 negative regulation of epithelial to mesenchymal transition Any process that decreases the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation proceeds. http://purl.obolibrary.org/obo/GO_0090325 regulation of locomotion involved in locomotory behavior http://purl.obolibrary.org/obo/GO_0040012 regulation of locomotion Any process that modulates the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement. http://purl.obolibrary.org/obo/GO_0090326 positive regulation of locomotion involved in locomotory behavior http://purl.obolibrary.org/obo/GO_0048520 positive regulation of behavior Any process that increases the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement. http://purl.obolibrary.org/obo/GO_0090327 negative regulation of locomotion involved in locomotory behavior http://purl.obolibrary.org/obo/GO_0090325 regulation of locomotion involved in locomotory behavior Any process that decreases the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement. http://purl.obolibrary.org/obo/GO_0090328 regulation of olfactory learning http://purl.obolibrary.org/obo/GO_0050795 regulation of behavior Any process that modulates the rate, frequency, or extent of olfactory learning. Olfactory learning is any process in an organism in which a relatively long-lasting adaptive behavioral change occurs in response to (repeated) exposure to an olfactory cue. http://purl.obolibrary.org/obo/GO_0090335 regulation of brown fat cell differentiation http://purl.obolibrary.org/obo/GO_0045598 regulation of fat cell differentiation Any process that modulates the rate, frequency, or extent of brown fat cell differentiation. Brown fat cell differentiation is the process in which a relatively unspecialized cell acquires specialized features of a brown adipocyte, an animal connective tissue cell involved in adaptive thermogenesis. Brown adipocytes contain multiple small droplets of triglycerides and a high number of mitochondria. http://purl.obolibrary.org/obo/GO_0090336 positive regulation of brown fat cell differentiation http://purl.obolibrary.org/obo/GO_0090335 regulation of brown fat cell differentiation Any process that increases the rate, frequency, or extent of brown fat cell differentiation. Brown fat cell differentiation is the process in which a relatively unspecialized cell acquires specialized features of a brown adipocyte, an animal connective tissue cell involved in adaptive thermogenesis. Brown adipocytes contain multiple small droplets of triglycerides and a high number of mitochondria. http://purl.obolibrary.org/obo/GO_0090394 negative regulation of excitatory postsynaptic potential http://purl.obolibrary.org/obo/GO_0098815 modulation of excitatory postsynaptic potential Any process that prevents the establishment or decreases the extent of the excitatory postsynaptic potential (EPSP) which is a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential. http://purl.obolibrary.org/obo/GO_0090454 glutamate transmembrane import into vacuole http://purl.obolibrary.org/obo/GO_0015800 acidic amino acid transport The directed movement of glutamate into the vacuole across the vacuolar membrane. http://purl.obolibrary.org/obo/GO_0090461 intracellular glutamate homeostasis http://purl.obolibrary.org/obo/GO_0080144 intracellular amino acid homeostasis A homeostatic process involved in the maintenance of a steady state level of glutamate within a cell. http://purl.obolibrary.org/obo/GO_0090513 L-histidine transmembrane import into vacuole http://purl.obolibrary.org/obo/GO_1902024 L-histidine transport The directed movement of L-histidine into the vacuole across the vacuolar membrane. http://purl.obolibrary.org/obo/GO_0090515 L-glutamate transmembrane import into vacuole http://purl.obolibrary.org/obo/GO_0090454 glutamate transmembrane import into vacuole The directed movement of L-glutamate into the vacuole across the vacuolar membrane. http://purl.obolibrary.org/obo/GO_0090521 podocyte cell migration http://purl.obolibrary.org/obo/GO_0010631 epithelial cell migration The orderly movement of a podocyte from one site to another, often during the development of a multicellular organism or multicellular structure. A podocyte is a specialized kidney epithelial cell. http://purl.obolibrary.org/obo/GO_0090634 microglial cell mediated cytotoxicity http://purl.obolibrary.org/obo/GO_0002444 myeloid leukocyte mediated immunity The directed killing of a target cell by a microglial cell. http://purl.obolibrary.org/obo/GO_0090685 RNA localization to nucleus http://purl.obolibrary.org/obo/GO_0006403 RNA localization A macromolecular localization process in which RNA is transported to and maintained in a location within the nucleus. http://purl.obolibrary.org/obo/GO_0090713 immunological memory process http://purl.obolibrary.org/obo/GO_0002376 immune system process Any process of the immune system that can contribute to the formation of immunological memory or an immune response based upon activation of immunological memory. http://purl.obolibrary.org/obo/GO_0097026 dendritic cell dendrite assembly http://purl.obolibrary.org/obo/GO_0120031 plasma membrane bounded cell projection assembly Formation of dendrites, branched cellular projections (or cytoplasmic extension) that are extended from the surface of a dendritic immune cell, and which enable the cell to sample luminal pathogens and increase the surface area for antigen presentation to T cells. http://purl.obolibrary.org/obo/GO_0097029 mature conventional dendritic cell differentiation http://purl.obolibrary.org/obo/GO_0097028 dendritic cell differentiation The process in which antigen-activated dendritic cells acquire the specialized features of a mature conventional dendritic cell. Mature conventional dendritic cells upregulate the surface expression of MHC molecules, chemokine receptors and adhesion molecules, and increase the number of dendrites (cytoplasmic protrusions) in preparation for migration to lymphoid organs where they present antigen to T cells. http://purl.obolibrary.org/obo/GO_0097048 dendritic cell apoptotic process http://purl.obolibrary.org/obo/GO_0071887 leukocyte apoptotic process Any apoptotic process in a dendritic cell, a cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation. http://purl.obolibrary.org/obo/GO_0097049 motor neuron apoptotic process http://purl.obolibrary.org/obo/GO_0051402 neuron apoptotic process Any apoptotic process in a motor neuron, an efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes movement. http://purl.obolibrary.org/obo/GO_0097050 type B pancreatic cell apoptotic process http://purl.obolibrary.org/obo/GO_1904019 epithelial cell apoptotic process Any apoptotic process in a type B pancreatic cell, a cell located towards center of the islets of Langerhans that secretes insulin. http://purl.obolibrary.org/obo/GO_0097054 L-glutamate biosynthetic process http://purl.obolibrary.org/obo/GO_0043650 dicarboxylic acid biosynthetic process The chemical reactions and pathways resulting in the formation of L-glutamate, the L enantiomer anion of 2-aminopentanedioic acid. http://purl.obolibrary.org/obo/GO_0097086 amniotic stem cell differentiation http://purl.obolibrary.org/obo/GO_0072497 mesenchymal stem cell differentiation The process whereby a relatively unspecialized cell acquires specialized features of an amniotic stem cell. An amniotic stem cell is a mesenchymal stem cell extracted from amniotic fluid. Amniotic stem cells are able to differentiate into various tissue types such as skin, cartilage, cardiac tissue, nerves, muscle, and bone. http://purl.obolibrary.org/obo/GO_0097096 facial suture morphogenesis http://purl.obolibrary.org/obo/GO_0097094 craniofacial suture morphogenesis The process in which any suture between facial bones is generated and organized. http://purl.obolibrary.org/obo/GO_0097104 postsynaptic membrane assembly http://purl.obolibrary.org/obo/GO_0071709 membrane assembly The aggregation, arrangement and bonding together of a set of components to form a postsynaptic membrane, a specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). http://purl.obolibrary.org/obo/GO_0097120 receptor localization to synapse http://purl.obolibrary.org/obo/GO_0051179 localization Any process in which a receptor is transported to, and/or maintained at the synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell. http://purl.obolibrary.org/obo/GO_0097152 mesenchymal cell apoptotic process http://purl.obolibrary.org/obo/GO_0006915 apoptotic process Any apoptotic process in a mesenchymal cell. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types. http://purl.obolibrary.org/obo/GO_0097177 mitochondrial ribosome binding http://purl.obolibrary.org/obo/GO_0043022 ribosome binding Binding to a mitochondrial ribosome. http://purl.obolibrary.org/obo/GO_0097187 dentinogenesis http://purl.obolibrary.org/obo/GO_0042475 odontogenesis of dentin-containing tooth The process whose specific outcome is the formation of dentin, the mineralized tissue that constitutes the major bulk of teeth. Dentin may be one of three types: primary dentin, secondary dentin, and tertiary dentin. http://purl.obolibrary.org/obo/GO_0097208 alveolar lamellar body http://purl.obolibrary.org/obo/GO_0042599 lamellar body A specialized secretory organelle found in type II pneumocytes and involved in the synthesis, secretion, and reutilization of pulmonary surfactant. http://purl.obolibrary.org/obo/GO_0097209 epidermal lamellar body http://purl.obolibrary.org/obo/GO_0042599 lamellar body A specialized secretory organelle found in keratinocytes and involved in the formation of an impermeable, lipid-containing membrane that serves as a water barrier and is required for correct skin barrier function. http://purl.obolibrary.org/obo/GO_0097212 lysosomal membrane organization http://purl.obolibrary.org/obo/GO_0061024 membrane organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lysosomal membrane. A lysosomal membrane is the lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm. http://purl.obolibrary.org/obo/GO_0097232 lamellar body membrane http://purl.obolibrary.org/obo/GO_0030667 secretory granule membrane The lipid bilayer surrounding a lamellar body. A lamellar body is a membrane-bounded organelle, specialized for the storage and secretion of various substances (surfactant phospholipids, glycoproteins and acid phosphates) which are arranged in the form of tightly packed, concentric, membrane sheets or lamellae. Has some similar properties to, but is distinct from, a lysosome. http://purl.obolibrary.org/obo/GO_0097233 alveolar lamellar body membrane http://purl.obolibrary.org/obo/GO_0097232 lamellar body membrane The lipid bilayer surrounding an alveolar lamellar body, a specialized secretory organelle found in type II pneumocytes and involved in the synthesis, secretion, and reutilization of pulmonary surfactant. http://purl.obolibrary.org/obo/GO_0097234 epidermal lamellar body membrane http://purl.obolibrary.org/obo/GO_0097232 lamellar body membrane The lipid bilayer surrounding an epidermal lamellar body, a specialized secretory organelle found in keratinocytes and involved in the formation of an impermeable, lipid-containing membrane that serves as a water barrier and is required for correct skin barrier function. http://purl.obolibrary.org/obo/GO_0097252 oligodendrocyte apoptotic process http://purl.obolibrary.org/obo/GO_0034349 glial cell apoptotic process Any apoptotic process in an oligodendrocyte. Oligodendrocytes belong to a class of large neuroglial (macroglial) cells in the central nervous system, where they form the insulating myelin sheath of axons. http://purl.obolibrary.org/obo/GO_0097254 renal tubular secretion http://purl.obolibrary.org/obo/GO_0003014 renal system process The elimination of substances from peritubular capillaries (or surrounding hemolymph in invertebrates) into the renal tubules to be incorporated subsequently into the urine. Substances that are secreted include organic anions, ammonia, potassium and drugs. http://purl.obolibrary.org/obo/GO_0097272 ammonium homeostasis http://purl.obolibrary.org/obo/GO_0098771 inorganic ion homeostasis Any biological process involved in the maintenance of an internal steady state of ammonium. http://purl.obolibrary.org/obo/GO_0097275 intracellular ammonium homeostasis http://purl.obolibrary.org/obo/GO_0097272 ammonium homeostasis A homeostatic process involved in the maintenance of a steady state level of ammonium within a cell. http://purl.obolibrary.org/obo/GO_0097283 keratinocyte apoptotic process http://purl.obolibrary.org/obo/GO_1904019 epithelial cell apoptotic process Any apoptotic process in a keratinocyte. A keratinocyte is an epidermal cell which synthesizes keratin and undergoes a characteristic change as it moves upward from the basal layers of the epidermis to the cornified (horny) layer of the skin. http://purl.obolibrary.org/obo/GO_0097284 hepatocyte apoptotic process http://purl.obolibrary.org/obo/GO_1904019 epithelial cell apoptotic process Any apoptotic process in a hepatocyte, the main structural component of the liver. http://purl.obolibrary.org/obo/GO_0097324 melanocyte migration http://purl.obolibrary.org/obo/GO_0010631 epithelial cell migration The orderly movement of melanocytes from one site to another, often during the development of a multicellular organism. A melanocyte is a pigment cell derived from the neural crest. It contains melanin-filled pigment granules, which give a brown to black appearance. http://purl.obolibrary.org/obo/GO_0097360 chorionic trophoblast cell proliferation http://purl.obolibrary.org/obo/GO_0008283 cell population proliferation The multiplication or reproduction of chorionic trophoblast cells, resulting in the expansion of their population. http://purl.obolibrary.org/obo/GO_0097386 glial cell projection http://purl.obolibrary.org/obo/GO_0120025 plasma membrane bounded cell projection A prolongation or process extending from a glial cell. http://purl.obolibrary.org/obo/GO_0097402 neuroblast migration http://purl.obolibrary.org/obo/GO_0016477 cell migration The orderly movement of a neuroblast from one site to another, often during the development of a multicellular organism or multicellular structure. A neuroblast is any cell that will divide and give rise to a neuron. http://purl.obolibrary.org/obo/GO_0097410 hippocampal interneuron differentiation http://purl.obolibrary.org/obo/GO_0021895 cerebral cortex neuron differentiation The process in which a relatively unspecialized cell acquires specialized features of a hippocampal interneuron. http://purl.obolibrary.org/obo/GO_0097427 microtubule bundle http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure An arrangement of closely apposed microtubules running parallel to each other. http://purl.obolibrary.org/obo/GO_0097432 hippocampal pyramidal neuron differentiation http://purl.obolibrary.org/obo/GO_0021895 cerebral cortex neuron differentiation The process in which a relatively unspecialized cell acquires specialized features of a hippocampal pyramidal neuron, a pyramidal cell of the hippocampus. http://purl.obolibrary.org/obo/GO_0097447 dendritic tree http://purl.obolibrary.org/obo/GO_0043005 neuron projection The entire complement of dendrites for a neuron, consisting of each primary dendrite and all its branches. http://purl.obolibrary.org/obo/GO_0097449 astrocyte projection http://purl.obolibrary.org/obo/GO_0097386 glial cell projection A prolongation or process extending from the soma of an astrocyte and wrapping around neurons. http://purl.obolibrary.org/obo/GO_0097454 Schwann cell microvillus http://purl.obolibrary.org/obo/GO_0097386 glial cell projection Small finger-like extension of a Schwann cell that contacts the nodal membrane. http://purl.obolibrary.org/obo/GO_0097457 hippocampal mossy fiber http://purl.obolibrary.org/obo/GO_0030424 axon An axon of a hippocampal granule cell, including dentate gyrus granule cell and CA3 granule cell, characterized by expansions (mossy fiber expansions) giving the fibers a mossy appearance. These unmyelinated axons were first described by Ramon y Cajal. http://purl.obolibrary.org/obo/GO_0097473 retinal rod cell apoptotic process http://purl.obolibrary.org/obo/GO_0051402 neuron apoptotic process Any apoptotic process in a retinal rod cell, one of the two photoreceptor cell types of the vertebrate retina. http://purl.obolibrary.org/obo/GO_0097474 retinal cone cell apoptotic process http://purl.obolibrary.org/obo/GO_0051402 neuron apoptotic process Any apoptotic process in a retinal cone cell, one of the two photoreceptor cell types of the vertebrate retina. http://purl.obolibrary.org/obo/GO_0097475 motor neuron migration http://purl.obolibrary.org/obo/GO_0001764 neuron migration The orderly movement of a motor neuron from one site to another. A motor neuron is an efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes movement. http://purl.obolibrary.org/obo/GO_0097476 spinal cord motor neuron migration http://purl.obolibrary.org/obo/GO_0097475 motor neuron migration The orderly movement of a spinal cord motor neuron from one site to another. A spinal cord motor neuron is a motor neuron that passes from the spinal cord toward or to a muscle and conducts an impulse that causes movement. http://purl.obolibrary.org/obo/GO_0097477 lateral motor column neuron migration http://purl.obolibrary.org/obo/GO_0097476 spinal cord motor neuron migration The orderly movement of a lateral motor column neuron from one site to another. A lateral motor column neuron is a motor neuron that is generated only on limb levels and send axons into the limb mesenchyme. http://purl.obolibrary.org/obo/GO_0097499 protein localization to non-motile cilium http://purl.obolibrary.org/obo/GO_0061512 protein localization to cilium A process in which a protein is transported to, or maintained in, a location within a non-motile cilium. http://purl.obolibrary.org/obo/GO_0097511 dendritic cell dendrite http://purl.obolibrary.org/obo/GO_0120025 plasma membrane bounded cell projection A branched cellular projection (or cytoplasmic extension) that is extended from the surface of a dendritic immune cell, and which enables the cell to sample luminal pathogens and increase the surface area for antigen presentation to T cells. http://purl.obolibrary.org/obo/GO_0097512 cardiac myofibril http://purl.obolibrary.org/obo/GO_0030016 myofibril A cardiac myofibril is a myofibril specific to cardiac muscle cells. http://purl.obolibrary.org/obo/GO_0097524 sperm plasma membrane http://purl.obolibrary.org/obo/GO_0005886 plasma membrane A plasma membrane that is part of a sperm cell. http://purl.obolibrary.org/obo/GO_0097534 lymphoid lineage cell migration http://purl.obolibrary.org/obo/GO_0016477 cell migration The orderly movement of a lymphoid lineage cell from one site to another. A lymphoid lineage cell, also called a lymphoid lineage restricted progenitor cell, is a progenitor cell restricted to the lymphoid lineage. http://purl.obolibrary.org/obo/GO_0097536 thymus epithelium morphogenesis http://purl.obolibrary.org/obo/GO_0002009 morphogenesis of an epithelium The process in which the thymus epithelium is generated and organized. http://purl.obolibrary.org/obo/GO_0097540 axonemal central pair http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure Part of the axoneme consisting of the inner two microtubule doublets of the 9+2 axoneme occurring in most motile cilia. http://purl.obolibrary.org/obo/GO_0097545 axonemal doublet microtubule http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure A cellular anatomical entity that is part of an axoneme consisting of a doublet microtubule. http://purl.obolibrary.org/obo/GO_0097623 potassium ion export across plasma membrane http://purl.obolibrary.org/obo/GO_0140115 export across plasma membrane The directed movement of potassium ions from inside of a cell, across the plasma membrane and into the extracellular region. http://purl.obolibrary.org/obo/GO_0097628 distal tip cell migration http://purl.obolibrary.org/obo/GO_0016477 cell migration The orderly movement of a distal tip cell. http://purl.obolibrary.org/obo/GO_0097649 A axonemal microtubule http://purl.obolibrary.org/obo/GO_0005879 axonemal microtubule A complete microtubule with 13 protofilaments that fuses with an incomplete microtubule called B tubule (containing 10 protofilaments only) to form an axonemal outer doublet. Inner and outer dynein arms, as well as the radial spoke, are attached to the A tubule. http://purl.obolibrary.org/obo/GO_0097650 B axonemal microtubule http://purl.obolibrary.org/obo/GO_0005879 axonemal microtubule An incomplete microtubule containing 10 protofilaments that fuses with a complete microtubule called A tubule (containing 13 protofilaments) to form an axonemal outer doublet. http://purl.obolibrary.org/obo/GO_0097711 ciliary basal body-plasma membrane docking http://purl.obolibrary.org/obo/GO_0140056 organelle localization by membrane tethering The docking of a cytosolic centriole/basal body to the plasma membrane via the ciliary transition fibers. In some species this may happen via an intermediate step, by first docking to the ciliary vesicle via the ciliary transition fibers. The basal body-ciliary vesicle then relocates to the plasma membrane, followed by the ciliary vesicle fusing with the plasma membrane, effectively attaching the basal body to the plasma membrane. http://purl.obolibrary.org/obo/GO_0097719 neural tissue regeneration http://purl.obolibrary.org/obo/GO_0042246 tissue regeneration The regrowth of neural tissue following its loss or destruction. http://purl.obolibrary.org/obo/GO_0097742 de novo centriole assembly http://purl.obolibrary.org/obo/GO_0098534 centriole assembly Centriole assembly in which a centriole arises de novo, rather than by replication from an existing centriole. This process may occur via different mechanisms. Examples include the deuterosome pathway in multicilated epithelial animal cells and formation of centrioles during parthenogenesis in some insects. http://purl.obolibrary.org/obo/GO_0098520 excitatory neuromuscular junction http://purl.obolibrary.org/obo/GO_0060076 excitatory synapse The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a post-synaptic potential responsible for muscle contraction. http://purl.obolibrary.org/obo/GO_0098522 neuromuscular junction of skeletal muscle fiber http://purl.obolibrary.org/obo/GO_0098981 cholinergic synapse A neuromuscular junction in which the target muscle cell is a skeletal muscle fiber. http://purl.obolibrary.org/obo/GO_0098523 neuromuscular junction of myotube http://purl.obolibrary.org/obo/GO_0031594 neuromuscular junction A neuromuscular junction in which the target muscle cell is a myotube. http://purl.obolibrary.org/obo/GO_0098524 neuromuscular junction of somatic muscle myotube http://purl.obolibrary.org/obo/GO_0098527 neuromuscular junction of somatic muscle A neuromuscular junction in which the target muscle cell is a somatic muscle myotube, such as an arthropod somatic muscle cell. http://purl.obolibrary.org/obo/GO_0098525 excitatory neuromuscular junction of somatic myotube http://purl.obolibrary.org/obo/GO_0098524 neuromuscular junction of somatic muscle myotube A neuromuscular junction that functions in the excitation of somatic muscle myotubes, such as an arthropod somatic muscle cells. http://purl.obolibrary.org/obo/GO_0098527 neuromuscular junction of somatic muscle http://purl.obolibrary.org/obo/GO_0031594 neuromuscular junction A neuromuscular junction in which the target muscle cell is a somatic muscle cell, such as those found in nematodes and arthropods. http://purl.obolibrary.org/obo/GO_0098529 neuromuscular junction development, skeletal muscle fiber http://purl.obolibrary.org/obo/GO_0007528 neuromuscular junction development A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuromuscular junction that targets a skeletal muscle fiber. http://purl.obolibrary.org/obo/GO_0098535 de novo centriole assembly involved in multi-ciliated epithelial cell differentiation http://purl.obolibrary.org/obo/GO_0097742 de novo centriole assembly Centriole assembly in which a centriole arises de novo by a process involving an electron-dense structure known as a deuterosome, rather than by duplication of an existing centriole, and occurring as part of multi-ciliated epithelial cell differentiation. http://purl.obolibrary.org/obo/GO_0098536 deuterosome http://purl.obolibrary.org/obo/GO_0043232 intracellular membraneless organelle A spherical, electron dense, cytoplasmic structure that is involved in de novo assembly of centrioles. http://purl.obolibrary.org/obo/GO_0098544 maintenance of protein complex location http://purl.obolibrary.org/obo/GO_0051235 maintenance of location Any process in which a protein complex is maintained in a location and prevented from moving elsewhere. These include sequestration, stabilization to prevent transport elsewhere and the active retrieval of protein complexes that move away. http://purl.obolibrary.org/obo/GO_0098545 maintenance of protein complex location in cytoplasm http://purl.obolibrary.org/obo/GO_0098544 maintenance of protein complex location Any process in which a protein complex is maintained in a specific location within the cytoplasm and is prevented from moving elsewhere. http://purl.obolibrary.org/obo/GO_0098594 mucin granule http://purl.obolibrary.org/obo/GO_0030141 secretory granule A secretory granule that contains mucin. http://purl.obolibrary.org/obo/GO_0098631 cell adhesion mediator activity http://purl.obolibrary.org/obo/GO_0050839 cell adhesion molecule binding The binding by a cell-adhesion protein on a cell surface to an adhesion molecule on another cell surface or an external substrate, to mediate adhesion of the cell to the external substrate or to another cell. http://purl.obolibrary.org/obo/GO_0098632 cell-cell adhesion mediator activity http://purl.obolibrary.org/obo/GO_0098631 cell adhesion mediator activity The binding by a cell-adhesion protein on the cell surface to an extracellular component of a different cell, to mediate adhesion of the cell to another cell. http://purl.obolibrary.org/obo/GO_0098633 collagen fibril binding http://purl.obolibrary.org/obo/GO_0050840 extracellular matrix binding Binding to a collagen fibril. http://purl.obolibrary.org/obo/GO_0098635 protein complex involved in cell-cell adhesion http://purl.obolibrary.org/obo/GO_0098636 protein complex involved in cell adhesion Any protein complex that is capable of carrying out some part of the process of cell-cell adhesion. http://purl.obolibrary.org/obo/GO_0098641 cadherin binding involved in cell-cell adhesion http://purl.obolibrary.org/obo/GO_0098632 cell-cell adhesion mediator activity Any cadherin binding that occurs as part of the process of cell-cell adhesion. http://purl.obolibrary.org/obo/GO_0098644 complex of collagen trimers http://purl.obolibrary.org/obo/GO_0099080 supramolecular complex A complex of collagen trimers such as a fibril or collagen network. http://purl.obolibrary.org/obo/GO_0098658 inorganic anion import across plasma membrane http://purl.obolibrary.org/obo/GO_0099587 inorganic ion import across plasma membrane The directed movement of inorganic anions from outside of a cell, across the plasma membrane and into the cytosol. http://purl.obolibrary.org/obo/GO_0098659 inorganic cation import across plasma membrane http://purl.obolibrary.org/obo/GO_0099587 inorganic ion import across plasma membrane The directed movement of inorganic cations from outside of a cell, across the plasma membrane and into the cytosol. http://purl.obolibrary.org/obo/GO_0098665 serotonin receptor complex http://purl.obolibrary.org/obo/GO_0043235 receptor complex A protein complex that is capable of serotonin receptor activity. http://purl.obolibrary.org/obo/GO_0098666 G protein-coupled serotonin receptor complex http://purl.obolibrary.org/obo/GO_0043235 receptor complex A protein complex that is capable of G protein-coupled serotonin receptor activity. http://purl.obolibrary.org/obo/GO_0098703 calcium ion import across plasma membrane http://purl.obolibrary.org/obo/GO_1902656 calcium ion import into cytosol The directed movement of calcium ions from outside of a cell, across the plasma membrane and into the cytosol. http://purl.obolibrary.org/obo/GO_0098704 carbohydrate import across plasma membrane http://purl.obolibrary.org/obo/GO_0034219 carbohydrate transmembrane transport The directed movement of a carbohydrate from outside of a cell, across the plasma membrane and into the cytosol. http://purl.obolibrary.org/obo/GO_0098708 D-glucose import across plasma membrane http://purl.obolibrary.org/obo/GO_0140271 hexose import across plasma membrane The directed movement of D-glucose from outside of a cell, across the plasma membrane and into the cytosol. http://purl.obolibrary.org/obo/GO_0098712 L-glutamate import across plasma membrane http://purl.obolibrary.org/obo/GO_0089718 amino acid import across plasma membrane The directed movement of L-glutamate from outside of a cell, across the plasma membrane and into the cytosol. http://purl.obolibrary.org/obo/GO_0098719 sodium ion import across plasma membrane http://purl.obolibrary.org/obo/GO_0098659 inorganic cation import across plasma membrane The directed movement of sodium ions from outside of a cell, across the plasma membrane and into the cytosol. http://purl.obolibrary.org/obo/GO_0098723 skeletal muscle myofibril http://purl.obolibrary.org/obo/GO_0030016 myofibril A myofibril of a skeletal muscle fiber. http://purl.obolibrary.org/obo/GO_0098739 import across plasma membrane http://purl.obolibrary.org/obo/GO_0098657 import into cell The directed movement of some substance from outside of a cell, across the plasma membrane and into the cytosol. http://purl.obolibrary.org/obo/GO_0098749 cerebellar neuron development http://purl.obolibrary.org/obo/GO_0021954 central nervous system neuron development The process whose specific outcome is the progression of a cerebellar neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. http://purl.obolibrary.org/obo/GO_0098804 non-motile cilium membrane http://purl.obolibrary.org/obo/GO_0060170 ciliary membrane The portion of the plasma membrane surrounding a non-motile cilium. http://purl.obolibrary.org/obo/GO_0098867 intramembranous bone growth http://purl.obolibrary.org/obo/GO_0098868 bone growth The increase in size or mass of an intramembranous bone that contributes to the shaping of the bone. http://purl.obolibrary.org/obo/GO_0098871 postsynaptic actin cytoskeleton http://purl.obolibrary.org/obo/GO_0099571 postsynaptic cytoskeleton The actin cytoskeleton that is part of a postsynapse. http://purl.obolibrary.org/obo/GO_0098877 neurotransmitter receptor transport to plasma membrane http://purl.obolibrary.org/obo/GO_0099637 neurotransmitter receptor transport The directed movement of neurotransmitter receptor to the plasma membrane in transport vesicles. http://purl.obolibrary.org/obo/GO_0098883 synapse pruning http://purl.obolibrary.org/obo/GO_0050808 synapse organization A cellular process that results in the controlled breakdown of synapse. After it starts the process is continuous until the synapse has disappeared. http://purl.obolibrary.org/obo/GO_0098901 regulation of cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_0098900 regulation of action potential Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a cardiac muscle cell. This typically occurs via modulation of the activity or expression of voltage-gated ion channels. http://purl.obolibrary.org/obo/GO_0098902 regulation of membrane depolarization during action potential http://purl.obolibrary.org/obo/GO_0003254 regulation of membrane depolarization Any process that modulates the rate, frequency or extent of membrane depolarization during an action potential. Membrane depolarization is the process in which membrane potential changes in the depolarizing direction from the resting potential. http://purl.obolibrary.org/obo/GO_0098903 regulation of membrane repolarization during action potential http://purl.obolibrary.org/obo/GO_0060306 regulation of membrane repolarization Any process that modulates the rate, frequency or extent of membrane repolarization during an action potential. Membrane repolarization is the process in which membrane potential changes in the repolarizing direction, towards the resting potential. http://purl.obolibrary.org/obo/GO_0098904 regulation of AV node cell action potential http://purl.obolibrary.org/obo/GO_0098901 regulation of cardiac muscle cell action potential Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in an atrioventricular node myocyte. This typically occurs via modulation of the activity or expression of voltage-gated ion channels. http://purl.obolibrary.org/obo/GO_0098905 regulation of bundle of His cell action potential http://purl.obolibrary.org/obo/GO_0098901 regulation of cardiac muscle cell action potential Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a cardiac muscle cell of the bundle of His. This typically occurs via modulation of the activity or expression of voltage-gated ion channels. http://purl.obolibrary.org/obo/GO_0098906 regulation of Purkinje myocyte action potential http://purl.obolibrary.org/obo/GO_0098901 regulation of cardiac muscle cell action potential Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a Purkinje myocyte. This typically occurs via modulation of the activity or expression of voltage-gated ion channels. http://purl.obolibrary.org/obo/GO_0098907 regulation of SA node cell action potential http://purl.obolibrary.org/obo/GO_0098901 regulation of cardiac muscle cell action potential Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in an SA node cardiac myocyte. This typically occurs via modulation of the activity or expression of voltage-gated ion channels. http://purl.obolibrary.org/obo/GO_0098908 regulation of neuronal action potential http://purl.obolibrary.org/obo/GO_0098900 regulation of action potential Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a neuron. This typically occurs via modulation of the activity or expression of voltage-gated ion channels. http://purl.obolibrary.org/obo/GO_0098909 regulation of cardiac muscle cell action potential involved in regulation of contraction http://purl.obolibrary.org/obo/GO_0098901 regulation of cardiac muscle cell action potential Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a cardiac muscle cell contributing to the regulation of its contraction. http://purl.obolibrary.org/obo/GO_0098910 regulation of atrial cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_1903779 regulation of cardiac conduction Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in an atrial cardiac muscle cell contributing to the regulation of its contraction. This typically occurs via modulation of the activity or expression of voltage-gated ion channels. http://purl.obolibrary.org/obo/GO_0098911 regulation of ventricular cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_0098901 regulation of cardiac muscle cell action potential Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a ventricular cardiac muscle cell contributing to the regulation of its contraction. This typically occurs via modulation of the activity or expression of voltage-gated ion channels. http://purl.obolibrary.org/obo/GO_0098912 membrane depolarization during atrial cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_0086012 membrane depolarization during cardiac muscle cell action potential The process in which atrial cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential. http://purl.obolibrary.org/obo/GO_0098913 membrane depolarization during ventricular cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_0086012 membrane depolarization during cardiac muscle cell action potential The process in which ventricular cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential. http://purl.obolibrary.org/obo/GO_0098914 membrane repolarization during atrial cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_0099624 atrial cardiac muscle cell membrane repolarization The process in which ions are transported across a membrane such that the atrial cardiomyocyte membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential. http://purl.obolibrary.org/obo/GO_0098915 membrane repolarization during ventricular cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_0099625 ventricular cardiac muscle cell membrane repolarization The process in which ions are transported across a membrane such that the ventricular cardiomyocyte membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential. http://purl.obolibrary.org/obo/GO_0098917 retrograde trans-synaptic signaling http://purl.obolibrary.org/obo/GO_0099537 trans-synaptic signaling Cell-cell signaling from post to pre-synapse, across the synaptic cleft. http://purl.obolibrary.org/obo/GO_0098920 retrograde trans-synaptic signaling by lipid http://purl.obolibrary.org/obo/GO_0099541 trans-synaptic signaling by lipid Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by a lipid ligand. http://purl.obolibrary.org/obo/GO_0098923 retrograde trans-synaptic signaling by soluble gas http://purl.obolibrary.org/obo/GO_0099543 trans-synaptic signaling by soluble gas Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by an soluble gas ligand. http://purl.obolibrary.org/obo/GO_0098924 retrograde trans-synaptic signaling by nitric oxide http://purl.obolibrary.org/obo/GO_0099548 trans-synaptic signaling by nitric oxide Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by nitric oxide. http://purl.obolibrary.org/obo/GO_0098925 retrograde trans-synaptic signaling by nitric oxide, modulating synaptic transmission http://purl.obolibrary.org/obo/GO_0099555 trans-synaptic signaling by nitric oxide, modulating synaptic transmission Modulation of synaptic transmission by cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by nitric oxide. http://purl.obolibrary.org/obo/GO_0098926 postsynaptic signal transduction http://purl.obolibrary.org/obo/GO_0007165 signal transduction Signal transduction in which the initial step occurs in a postsynapse. http://purl.obolibrary.org/obo/GO_0098928 presynaptic signal transduction http://purl.obolibrary.org/obo/GO_0007165 signal transduction Signal transduction in which the initial step occurs in a presynapse. http://purl.obolibrary.org/obo/GO_0098934 retrograde dendritic transport http://purl.obolibrary.org/obo/GO_0098935 dendritic transport The directed movement of organelles or molecules along microtubules in a dendrite from the postsynapse towards the cell body. http://purl.obolibrary.org/obo/GO_0098935 dendritic transport http://purl.obolibrary.org/obo/GO_0008088 axo-dendritic transport The directed movement of organelles or molecules along microtubules in dendrites. http://purl.obolibrary.org/obo/GO_0098937 anterograde dendritic transport http://purl.obolibrary.org/obo/GO_0098935 dendritic transport The directed movement of organelles or molecules along microtubules from the cell body toward the postsynapse in dendrites. http://purl.obolibrary.org/obo/GO_0098939 dendritic transport of mitochondrion http://purl.obolibrary.org/obo/GO_0098935 dendritic transport The directed movement of mitochondria along microtubules in nerve cell dendrites. http://purl.obolibrary.org/obo/GO_0098940 anterograde trans-synaptic signaling by nitric oxide http://purl.obolibrary.org/obo/GO_0099548 trans-synaptic signaling by nitric oxide Cell-cell signaling from presynapse to postynapse, across the synaptic cleft, mediated by nitric oxide. http://purl.obolibrary.org/obo/GO_0098957 anterograde axonal transport of mitochondrion http://purl.obolibrary.org/obo/GO_0019896 axonal transport of mitochondrion The directed movement of mitochondria along microtubules in axons away from the cell body and towards the presynapse. http://purl.obolibrary.org/obo/GO_0098958 retrograde axonal transport of mitochondrion http://purl.obolibrary.org/obo/GO_0019896 axonal transport of mitochondrion The directed movement of mitochondria along microtubules in axons towards the cell body and away from the presynapse. http://purl.obolibrary.org/obo/GO_0098959 retrograde dendritic transport of mitochondrion http://purl.obolibrary.org/obo/GO_0098939 dendritic transport of mitochondrion The directed movement of mitochondria along microtubules in dendrites towards the cell body and away from the postsynapse. http://purl.obolibrary.org/obo/GO_0098960 postsynaptic neurotransmitter receptor activity http://purl.obolibrary.org/obo/GO_0030594 neurotransmitter receptor activity Neurotransmitter receptor activity occurring in the postsynaptic membrane during synaptic transmission. http://purl.obolibrary.org/obo/GO_0098961 dendritic transport of ribonucleoprotein complex http://purl.obolibrary.org/obo/GO_0098935 dendritic transport The directed movement of a ribonucleoprotein complex along microtubules in nerve cell dendrites. http://purl.obolibrary.org/obo/GO_0098967 exocytic insertion of neurotransmitter receptor to postsynaptic membrane http://purl.obolibrary.org/obo/GO_0099072 regulation of postsynaptic membrane neurotransmitter receptor levels The exocytic fusion of neurotransmitter receptor containing vesicles with the postsynaptic membrane resulting in the integration of NT receptors, enabling them to participate in neurotransmitter reception. This process includes tethering and docking steps that prepare vesicles for fusion. http://purl.obolibrary.org/obo/GO_0098969 neurotransmitter receptor transport to postsynaptic membrane http://purl.obolibrary.org/obo/GO_1903540 establishment of protein localization to postsynaptic membrane The directed movement of neurotransmitter receptor to the postsynaptic membrane in transport vesicles. http://purl.obolibrary.org/obo/GO_0098971 anterograde dendritic transport of neurotransmitter receptor complex http://purl.obolibrary.org/obo/GO_0098937 anterograde dendritic transport The directed movement of a neurotransmitter receptor complex along microtubules in nerve cell dendrites towards the postsynapse. http://purl.obolibrary.org/obo/GO_0098972 anterograde dendritic transport of mitochondrion http://purl.obolibrary.org/obo/GO_0098939 dendritic transport of mitochondrion The directed movement of mitochondria along microtubules in dendrites towards the postsynapse and away from the cell body. http://purl.obolibrary.org/obo/GO_0098974 postsynaptic actin cytoskeleton organization http://purl.obolibrary.org/obo/GO_0099188 postsynaptic cytoskeleton organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins in the postsynaptic actin cytoskeleton. http://purl.obolibrary.org/obo/GO_0098975 postsynapse of neuromuscular junction http://purl.obolibrary.org/obo/GO_0098794 postsynapse The postsynapse of a neuromuscular junction. In vertebrate muscles this includes the motor end-plate, consisting of postjunctional folds of the sarcolemma. http://purl.obolibrary.org/obo/GO_0098976 excitatory chemical synaptic transmission http://purl.obolibrary.org/obo/GO_0007268 chemical synaptic transmission Synaptic transmission that results in an excitatory postsynaptic potential. http://purl.obolibrary.org/obo/GO_0098978 glutamatergic synapse http://purl.obolibrary.org/obo/GO_0045202 synapse A synapse that uses glutamate as a neurotransmitter. http://purl.obolibrary.org/obo/GO_0098981 cholinergic synapse http://purl.obolibrary.org/obo/GO_0045202 synapse A synapse that uses acetylcholine as a neurotransmitter. http://purl.obolibrary.org/obo/GO_0098982 GABA-ergic synapse http://purl.obolibrary.org/obo/GO_0045202 synapse A synapse that uses GABA as a neurotransmitter. These synapses are typically inhibitory. http://purl.obolibrary.org/obo/GO_0098991 kainate selective glutamate receptor signaling pathway http://purl.obolibrary.org/obo/GO_0035235 ionotropic glutamate receptor signaling pathway The series of molecular signals initiated by glutamate binding to an kainate-selective glutamate receptor on the surface of the target cell, followed by the movement of ions through a channel in the receptor complex, ending with the regulation of a downstream cellular process, e.g. transcription. http://purl.obolibrary.org/obo/GO_0098992 neuronal dense core vesicle http://purl.obolibrary.org/obo/GO_0031045 dense core granule A dense core vesicle (granule) that is part of a neuron. These vesicles typically contain neuropeptides. They can be found in all parts of neurons, including the soma, dendrites, axonal swellings (varicosities) and synaptic terminals. http://purl.obolibrary.org/obo/GO_0099011 neuronal dense core vesicle exocytosis http://purl.obolibrary.org/obo/GO_1990504 dense core granule exocytosis The secretion of molecules (e.g. neuropeptides, insulin-related peptides or neuromodulators such as serotonin and dopamine) contained within a neuronal dense core vesicle by fusion of the granule with the plasma membrane of a neuron in response to increased cytosolic calcium levels. http://purl.obolibrary.org/obo/GO_0099012 neuronal dense core vesicle membrane http://purl.obolibrary.org/obo/GO_0032127 dense core granule membrane The lipid bilayer surrounding a neuronal dense core vesicle. http://purl.obolibrary.org/obo/GO_0099014 neuronal dense core vesicle organization http://purl.obolibrary.org/obo/GO_0061109 dense core granule organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuronal dense core vesicle. http://purl.obolibrary.org/obo/GO_0099054 presynapse assembly http://purl.obolibrary.org/obo/GO_0099172 presynapse organization The aggregation, arrangement and bonding together of a set of components to form a presynapse. http://purl.obolibrary.org/obo/GO_0099068 postsynapse assembly http://purl.obolibrary.org/obo/GO_0022607 cellular component assembly The aggregation, arrangement and bonding together of a set of components to form a postsynapse. http://purl.obolibrary.org/obo/GO_0099072 regulation of postsynaptic membrane neurotransmitter receptor levels http://purl.obolibrary.org/obo/GO_0065008 regulation of biological quality Any process that regulates the the local concentration of neurotransmitter receptor at the postsynaptic membrane. http://purl.obolibrary.org/obo/GO_0099074 mitochondrion to lysosome vesicle-mediated transport http://purl.obolibrary.org/obo/GO_0099075 mitochondrion-derived vesicle mediated transport Vesicle-mediated transport of cargo from the mitochondrion to the lysosome, mediated by a mitochondrion-derived vesicle. http://purl.obolibrary.org/obo/GO_0099075 mitochondrion-derived vesicle mediated transport http://purl.obolibrary.org/obo/GO_0016192 vesicle-mediated transport Vesicle-mediated transport of cargo from the mitochondrion by a mitochondrion-derived vesicle. http://purl.obolibrary.org/obo/GO_0099081 supramolecular polymer http://purl.obolibrary.org/obo/GO_0099080 supramolecular complex A polymeric supramolecular structure. http://purl.obolibrary.org/obo/GO_0099082 retrograde trans-synaptic signaling by neuropeptide http://purl.obolibrary.org/obo/GO_0099540 trans-synaptic signaling by neuropeptide Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by a neuropeptide. http://purl.obolibrary.org/obo/GO_0099083 retrograde trans-synaptic signaling by neuropeptide, modulating synaptic transmission http://purl.obolibrary.org/obo/GO_0099551 trans-synaptic signaling by neuropeptide, modulating synaptic transmission Modulation of synaptic transmission by cell-cell signaling across the synaptic cleft from postsynapse to presynapse, mediated by a neuropeptide. http://purl.obolibrary.org/obo/GO_0099093 calcium export from the mitochondrion http://purl.obolibrary.org/obo/GO_0051209 release of sequestered calcium ion into cytosol A process in which a calcium ion (Ca2+) is transported out of the mitochondrial matrix, and into the cytosol. http://purl.obolibrary.org/obo/GO_0099096 vestibular calyx terminal http://purl.obolibrary.org/obo/GO_0043679 axon terminus The giant, cup-shaped axon terminal of a vestibular afferent neuron, serving as a post-synaptic contact to a type I hair cell. http://purl.obolibrary.org/obo/GO_0099112 microtubule polymerization based protein transport http://purl.obolibrary.org/obo/GO_0099118 microtubule-based protein transport The transport of a protein driven by polymerization of a microtubule to which it is attached. http://purl.obolibrary.org/obo/GO_0099118 microtubule-based protein transport http://purl.obolibrary.org/obo/GO_0099111 microtubule-based transport A microtubule-based process that results in the transport of proteins. http://purl.obolibrary.org/obo/GO_0099123 somato-dendritic dopamine secretion http://purl.obolibrary.org/obo/GO_0014046 dopamine secretion The regulated release of dopamine from the somatodendritic compartment (cell body or dendrites) of a neuron. http://purl.obolibrary.org/obo/GO_0099519 dense core granule cytoskeletal transport http://purl.obolibrary.org/obo/GO_1901950 dense core granule transport The directed movement of dense core granules along cytoskeletal fibers, such as microtubules or actin filaments. http://purl.obolibrary.org/obo/GO_0099523 presynaptic cytosol http://purl.obolibrary.org/obo/GO_0005829 cytosol The region of the cytosol consisting of all cytosol that is part of the presynapse. http://purl.obolibrary.org/obo/GO_0099524 postsynaptic cytosol http://purl.obolibrary.org/obo/GO_0005829 cytosol The region of the cytosol consisting of all cytosol that is part of the postsynapse. http://purl.obolibrary.org/obo/GO_0099525 presynaptic dense core vesicle exocytosis http://purl.obolibrary.org/obo/GO_0099011 neuronal dense core vesicle exocytosis The secretion of molecules (e.g. neuropeptides and neuromodulators such as serotonin and dopamine) contained within a membrane-bounced dense in response to increased presynaptic cytosolic calcium levels. http://purl.obolibrary.org/obo/GO_0099530 G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential http://purl.obolibrary.org/obo/GO_0004930 G protein-coupled receptor activity A G protein-coupled receptor activity occurring in the postsynaptic membrane that is part of a GPCR signaling pathway that positively regulates ion channel activity in the postsynaptic membrane. http://purl.obolibrary.org/obo/GO_0099533 positive regulation of presynaptic cytosolic calcium concentration http://purl.obolibrary.org/obo/GO_0007204 positive regulation of cytosolic calcium ion concentration Any process that increases the concentration of calcium ions in the presynaptic cytosol. http://purl.obolibrary.org/obo/GO_0099536 synaptic signaling http://purl.obolibrary.org/obo/GO_0007267 cell-cell signaling Cell-cell signaling to, from or within a synapse. http://purl.obolibrary.org/obo/GO_0099537 trans-synaptic signaling http://purl.obolibrary.org/obo/GO_0099536 synaptic signaling Cell-cell signaling in either direction across the synaptic cleft. http://purl.obolibrary.org/obo/GO_0099538 synaptic signaling via neuropeptide http://purl.obolibrary.org/obo/GO_0099536 synaptic signaling Cell-cell signaling to or from a synapse, mediated by a peptide. http://purl.obolibrary.org/obo/GO_0099539 neuropeptide secretion from presynapse http://purl.obolibrary.org/obo/GO_0099525 presynaptic dense core vesicle exocytosis The secretion of neuropeptides contained within a dense core vesicle by fusion of the granule with the presynaptic membrane, stimulated by a rise in cytosolic calcium ion concentration. http://purl.obolibrary.org/obo/GO_0099540 trans-synaptic signaling by neuropeptide http://purl.obolibrary.org/obo/GO_0099538 synaptic signaling via neuropeptide Cell-cell signaling between presynapse and postsynapse mediated by a peptide ligand crossing the synaptic cleft. http://purl.obolibrary.org/obo/GO_0099541 trans-synaptic signaling by lipid http://purl.obolibrary.org/obo/GO_0099537 trans-synaptic signaling Cell-cell signaling from post to pre-synapse, across the synaptic cleft, mediated by a lipid. http://purl.obolibrary.org/obo/GO_0099543 trans-synaptic signaling by soluble gas http://purl.obolibrary.org/obo/GO_0099537 trans-synaptic signaling Cell-cell signaling between presynapse and postsynapse mediated by a soluble gas ligand crossing the synaptic cleft. http://purl.obolibrary.org/obo/GO_0099546 protein catabolic process, modulating synaptic transmission http://purl.obolibrary.org/obo/GO_0140246 protein catabolic process at synapse Any protein degradation process, occurring at a presynapse, that regulates synaptic transmission. http://purl.obolibrary.org/obo/GO_0099547 regulation of translation at synapse, modulating synaptic transmission http://purl.obolibrary.org/obo/GO_0050804 modulation of chemical synaptic transmission Any process that modulates synaptic transmission by regulating translation occurring at the synapse. http://purl.obolibrary.org/obo/GO_0099548 trans-synaptic signaling by nitric oxide http://purl.obolibrary.org/obo/GO_0099543 trans-synaptic signaling by soluble gas Cell-cell signaling between presynapse and postsynapse mediated by nitric oxide. http://purl.obolibrary.org/obo/GO_0099550 trans-synaptic signaling, modulating synaptic transmission http://purl.obolibrary.org/obo/GO_0099537 trans-synaptic signaling Cell-cell signaling between presynapse and postsynapse, across the synaptic cleft, that modulates the synaptic transmission properties of the synapse. http://purl.obolibrary.org/obo/GO_0099551 trans-synaptic signaling by neuropeptide, modulating synaptic transmission http://purl.obolibrary.org/obo/GO_0099550 trans-synaptic signaling, modulating synaptic transmission Cell-cell signaling between presynapse and postsynapse, via the vesicular release and reception of neuropeptide molecules, that modulates the synaptic transmission properties of the synapse. http://purl.obolibrary.org/obo/GO_0099552 trans-synaptic signaling by lipid, modulating synaptic transmission http://purl.obolibrary.org/obo/GO_0099550 trans-synaptic signaling, modulating synaptic transmission Cell-cell signaling between presynapse and postsynapse, via the release and reception of lipid molecules, that modulates the synaptic transmission properties of the synapse. http://purl.obolibrary.org/obo/GO_0099554 trans-synaptic signaling by soluble gas, modulating synaptic transmission http://purl.obolibrary.org/obo/GO_0099550 trans-synaptic signaling, modulating synaptic transmission Cell-cell signaling between presynapse and postsynapse, via the release and reception of gaseous molecules, that modulates the synaptic transmission properties of the synapse. http://purl.obolibrary.org/obo/GO_0099555 trans-synaptic signaling by nitric oxide, modulating synaptic transmission http://purl.obolibrary.org/obo/GO_0099554 trans-synaptic signaling by soluble gas, modulating synaptic transmission Cell-cell signaling between presynapse and postsynapse, via the release and reception of nitric oxide molecules, that modulates the synaptic transmission properties of the synapse. http://purl.obolibrary.org/obo/GO_0099571 postsynaptic cytoskeleton http://purl.obolibrary.org/obo/GO_0005856 cytoskeleton The portion of the cytoskeleton contained within the postsynapse. http://purl.obolibrary.org/obo/GO_0099574 regulation of protein catabolic process at synapse, modulating synaptic transmission http://purl.obolibrary.org/obo/GO_0050804 modulation of chemical synaptic transmission Any process that modulates synaptic transmission by regulating protein degradation at the synapse. http://purl.obolibrary.org/obo/GO_0099575 regulation of protein catabolic process at presynapse, modulating synaptic transmission http://purl.obolibrary.org/obo/GO_0099171 presynaptic modulation of chemical synaptic transmission Any process that modulates synaptic transmission by regulating a catabolic process occurring at a presynapse. http://purl.obolibrary.org/obo/GO_0099576 regulation of protein catabolic process at postsynapse, modulating synaptic transmission http://purl.obolibrary.org/obo/GO_0099170 postsynaptic modulation of chemical synaptic transmission Any process that modulates synaptic transmission by regulating a catabolic process occurring at a postsynapse. http://purl.obolibrary.org/obo/GO_0099577 regulation of translation at presynapse, modulating synaptic transmission http://purl.obolibrary.org/obo/GO_0140244 regulation of translation at presynapse Any process that modulates synaptic transmission by regulating translation occurring at the presynapse. http://purl.obolibrary.org/obo/GO_0099578 regulation of translation at postsynapse, modulating synaptic transmission http://purl.obolibrary.org/obo/GO_0099170 postsynaptic modulation of chemical synaptic transmission Any process that modulates synaptic transmission by regulating translation occurring at the postsynapse. http://purl.obolibrary.org/obo/GO_0099585 release of sequestered calcium ion into presynaptic cytosol http://purl.obolibrary.org/obo/GO_0051209 release of sequestered calcium ion into cytosol The process in which calcium ions sequestered in the endoplasmic reticulum, Golgi apparatus or mitochondria are released into the presynaptic cytosol. http://purl.obolibrary.org/obo/GO_0099586 release of sequestered calcium ion into postsynaptic cytosol http://purl.obolibrary.org/obo/GO_0051209 release of sequestered calcium ion into cytosol The process in which calcium ions sequestered in the endoplasmic reticulum, Golgi apparatus or mitochondria are released into the postsynaptic cytosol. http://purl.obolibrary.org/obo/GO_0099587 inorganic ion import across plasma membrane http://purl.obolibrary.org/obo/GO_0098739 import across plasma membrane The directed movement of inorganic ions from outside of a cell, across the plasma membrane and into the cytosol. http://purl.obolibrary.org/obo/GO_0099588 positive regulation of postsynaptic cytosolic calcium concentration http://purl.obolibrary.org/obo/GO_0007204 positive regulation of cytosolic calcium ion concentration Any process that increases the concentration of calcium ions in the postsynaptic cytosol. http://purl.obolibrary.org/obo/GO_0099601 regulation of neurotransmitter receptor activity http://purl.obolibrary.org/obo/GO_0010469 regulation of signaling receptor activity Any process that modulates the frequency, rate or extent of neurotransmitter receptor activity. Modulation may be via an effect on ligand affinity, or effector function such as ion selectivity or pore opening/closing in ionotropic receptors. http://purl.obolibrary.org/obo/GO_0099622 cardiac muscle cell membrane repolarization http://purl.obolibrary.org/obo/GO_0086009 membrane repolarization The process in which ions are transported across the plasma membrane of a cardiac muscle cell such that the membrane potential changes in the repolarizing direction, toward the steady state potential. For example, the repolarization during an action potential is from a positive membrane potential towards a negative resting potential. http://purl.obolibrary.org/obo/GO_0099635 voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels http://purl.obolibrary.org/obo/GO_0005245 voltage-gated calcium channel activity Positive regulation of presynaptic cytosolic calcium ion concentrations via the directed movement of calcium ions across the plasma-membrane into the cytosol via the action of voltage-gated calcium ion channels. This is the first step in synaptic transmission. http://purl.obolibrary.org/obo/GO_0099637 neurotransmitter receptor transport http://purl.obolibrary.org/obo/GO_0031503 protein-containing complex localization The directed movement of neurotransmitter receptors. http://purl.obolibrary.org/obo/GO_0099640 axo-dendritic protein transport http://purl.obolibrary.org/obo/GO_0098840 protein transport along microtubule The directed movement of proteins along microtubules in neuron projections. http://purl.obolibrary.org/obo/GO_0099641 anterograde axonal protein transport http://purl.obolibrary.org/obo/GO_1905383 protein localization to presynapse The directed movement of proteins along microtubules from the cell body toward the cell periphery in nerve cell axons. http://purl.obolibrary.org/obo/GO_0099642 retrograde axonal protein transport http://purl.obolibrary.org/obo/GO_0099640 axo-dendritic protein transport The directed movement of proteins along microtubules from the cell periphery toward the cell body in nerve cell axons. http://purl.obolibrary.org/obo/GO_0099703 induction of synaptic vesicle exocytosis by positive regulation of presynaptic cytosolic calcium ion concentration http://purl.obolibrary.org/obo/GO_2000302 positive regulation of synaptic vesicle exocytosis The induction of synaptic vesicle release by any process that leads to a rise in intracellular calcium ion concentration at the presynapse. This is the first step in synaptic transmission. http://purl.obolibrary.org/obo/GO_0101010 pulmonary blood vessel remodeling http://purl.obolibrary.org/obo/GO_0001974 blood vessel remodeling The reorganization or renovation of existing pulmonary blood vessels. http://purl.obolibrary.org/obo/GO_0101023 vascular endothelial cell proliferation http://purl.obolibrary.org/obo/GO_0001935 endothelial cell proliferation The multiplication or reproduction of blood vessel endothelial cells, resulting in the expansion of a cell population. http://purl.obolibrary.org/obo/GO_0101024 mitotic nuclear membrane organization http://purl.obolibrary.org/obo/GO_0071763 nuclear membrane organization A mitotic cell cycle process which results in the assembly, arrangement, or disassembly of the nuclear inner or outer membrane during mitosis. http://purl.obolibrary.org/obo/GO_0101025 nuclear membrane biogenesis http://purl.obolibrary.org/obo/GO_0044091 membrane biogenesis The process in which a nuclear membrane is synthesized, aggregates, and bonds together. http://purl.obolibrary.org/obo/GO_1900015 regulation of cytokine production involved in inflammatory response http://purl.obolibrary.org/obo/GO_0001817 regulation of cytokine production Any process that modulates the frequency, rate or extent of cytokine production involved in inflammatory response. http://purl.obolibrary.org/obo/GO_1900016 negative regulation of cytokine production involved in inflammatory response http://purl.obolibrary.org/obo/GO_1900015 regulation of cytokine production involved in inflammatory response Any process that stops, prevents or reduces the frequency, rate or extent of cytokine production involved in inflammatory response. http://purl.obolibrary.org/obo/GO_1900017 positive regulation of cytokine production involved in inflammatory response http://purl.obolibrary.org/obo/GO_1900015 regulation of cytokine production involved in inflammatory response Any process that activates or increases the frequency, rate or extent of cytokine production involved in inflammatory response. http://purl.obolibrary.org/obo/GO_1900073 regulation of neuromuscular synaptic transmission http://purl.obolibrary.org/obo/GO_0050804 modulation of chemical synaptic transmission Any process that modulates the frequency, rate or extent of neuromuscular synaptic transmission. http://purl.obolibrary.org/obo/GO_1900074 negative regulation of neuromuscular synaptic transmission http://purl.obolibrary.org/obo/GO_1900073 regulation of neuromuscular synaptic transmission Any process that stops, prevents or reduces the frequency, rate or extent of neuromuscular synaptic transmission. http://purl.obolibrary.org/obo/GO_1900075 positive regulation of neuromuscular synaptic transmission http://purl.obolibrary.org/obo/GO_1900073 regulation of neuromuscular synaptic transmission Any process that activates or increases the frequency, rate or extent of neuromuscular synaptic transmission. http://purl.obolibrary.org/obo/GO_1900098 regulation of plasma cell differentiation http://purl.obolibrary.org/obo/GO_0050776 regulation of immune response Any process that modulates the frequency, rate or extent of plasma cell differentiation. http://purl.obolibrary.org/obo/GO_1900099 negative regulation of plasma cell differentiation http://purl.obolibrary.org/obo/GO_1900098 regulation of plasma cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of plasma cell differentiation. http://purl.obolibrary.org/obo/GO_1900100 positive regulation of plasma cell differentiation http://purl.obolibrary.org/obo/GO_1900098 regulation of plasma cell differentiation Any process that activates or increases the frequency, rate or extent of plasma cell differentiation. http://purl.obolibrary.org/obo/GO_1900115 extracellular regulation of signal transduction http://purl.obolibrary.org/obo/GO_0009966 regulation of signal transduction Any regulation of signal transduction that takes place in the extracellular region. http://purl.obolibrary.org/obo/GO_1900117 regulation of execution phase of apoptosis http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of execution phase of apoptosis. http://purl.obolibrary.org/obo/GO_1900118 negative regulation of execution phase of apoptosis http://purl.obolibrary.org/obo/GO_1900117 regulation of execution phase of apoptosis Any process that stops, prevents or reduces the frequency, rate or extent of execution phase of apoptosis. http://purl.obolibrary.org/obo/GO_1900119 positive regulation of execution phase of apoptosis http://purl.obolibrary.org/obo/GO_0043065 positive regulation of apoptotic process Any process that activates or increases the frequency, rate or extent of execution phase of apoptosis. http://purl.obolibrary.org/obo/GO_1900125 regulation of hyaluronan biosynthetic process http://purl.obolibrary.org/obo/GO_0032885 regulation of polysaccharide biosynthetic process Any process that modulates the frequency, rate or extent of hyaluronan biosynthetic process. http://purl.obolibrary.org/obo/GO_1900126 negative regulation of hyaluronan biosynthetic process http://purl.obolibrary.org/obo/GO_0045912 negative regulation of carbohydrate metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of hyaluronan biosynthetic process. http://purl.obolibrary.org/obo/GO_1900127 positive regulation of hyaluronan biosynthetic process http://purl.obolibrary.org/obo/GO_0045913 positive regulation of carbohydrate metabolic process Any process that activates or increases the frequency, rate or extent of hyaluronan biosynthetic process. http://purl.obolibrary.org/obo/GO_1900131 negative regulation of lipid binding http://purl.obolibrary.org/obo/GO_0051100 negative regulation of binding Any process that stops, prevents or reduces the frequency, rate or extent of lipid binding. http://purl.obolibrary.org/obo/GO_1900133 regulation of renin secretion into blood stream http://purl.obolibrary.org/obo/GO_0098801 regulation of renal system process Any process that modulates the frequency, rate or extent of renin secretion into blood stream. http://purl.obolibrary.org/obo/GO_1900134 negative regulation of renin secretion into blood stream http://purl.obolibrary.org/obo/GO_1900133 regulation of renin secretion into blood stream Any process that stops, prevents or reduces the frequency, rate or extent of renin secretion into blood stream. http://purl.obolibrary.org/obo/GO_1900135 positive regulation of renin secretion into blood stream http://purl.obolibrary.org/obo/GO_1900133 regulation of renin secretion into blood stream Any process that activates or increases the frequency, rate or extent of renin secretion into blood stream. http://purl.obolibrary.org/obo/GO_1900141 regulation of oligodendrocyte apoptotic process http://purl.obolibrary.org/obo/GO_0034350 regulation of glial cell apoptotic process Any process that modulates the frequency, rate or extent of oligodendrocyte apoptotic process. http://purl.obolibrary.org/obo/GO_1900142 negative regulation of oligodendrocyte apoptotic process http://purl.obolibrary.org/obo/GO_1900141 regulation of oligodendrocyte apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of oligodendrocyte apoptotic process. http://purl.obolibrary.org/obo/GO_1900143 positive regulation of oligodendrocyte apoptotic process http://purl.obolibrary.org/obo/GO_1900141 regulation of oligodendrocyte apoptotic process Any process that activates or increases the frequency, rate or extent of oligodendrocyte apoptotic process. http://purl.obolibrary.org/obo/GO_1900147 regulation of Schwann cell migration http://purl.obolibrary.org/obo/GO_1903975 regulation of glial cell migration Any process that modulates the frequency, rate or extent of Schwann cell migration. http://purl.obolibrary.org/obo/GO_1900148 negative regulation of Schwann cell migration http://purl.obolibrary.org/obo/GO_1900147 regulation of Schwann cell migration Any process that stops, prevents or reduces the frequency, rate or extent of Schwann cell migration. http://purl.obolibrary.org/obo/GO_1900149 positive regulation of Schwann cell migration http://purl.obolibrary.org/obo/GO_1903977 positive regulation of glial cell migration Any process that activates or increases the frequency, rate or extent of Schwann cell migration. http://purl.obolibrary.org/obo/GO_1900158 negative regulation of bone mineralization involved in bone maturation http://purl.obolibrary.org/obo/GO_0030502 negative regulation of bone mineralization Any process that stops, prevents or reduces the frequency, rate or extent of bone mineralization involved in bone maturation. http://purl.obolibrary.org/obo/GO_1900159 positive regulation of bone mineralization involved in bone maturation http://purl.obolibrary.org/obo/GO_0030501 positive regulation of bone mineralization Any process that activates or increases the frequency, rate or extent of bone mineralization involved in bone maturation. http://purl.obolibrary.org/obo/GO_1900160 plastid chromosome packaging http://purl.obolibrary.org/obo/GO_0051276 chromosome organization A process in which plastidial DNA and associated proteins organize into a compact, orderly structure. http://purl.obolibrary.org/obo/GO_1900193 regulation of oocyte maturation http://purl.obolibrary.org/obo/GO_2000241 regulation of reproductive process Any process that modulates the frequency, rate or extent of oocyte maturation. http://purl.obolibrary.org/obo/GO_1900194 negative regulation of oocyte maturation http://purl.obolibrary.org/obo/GO_2000242 negative regulation of reproductive process Any process that stops, prevents or reduces the frequency, rate or extent of oocyte maturation. http://purl.obolibrary.org/obo/GO_1900195 positive regulation of oocyte maturation http://purl.obolibrary.org/obo/GO_2000243 positive regulation of reproductive process Any process that activates or increases the frequency, rate or extent of oocyte maturation. http://purl.obolibrary.org/obo/GO_1900200 mesenchymal cell apoptotic process involved in metanephros development http://purl.obolibrary.org/obo/GO_0097152 mesenchymal cell apoptotic process Any mesenchymal cell apoptotic process that is involved in metanephros development. http://purl.obolibrary.org/obo/GO_1900206 regulation of pronephric nephron tubule development http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of pronephric nephron tubule development. http://purl.obolibrary.org/obo/GO_1900207 negative regulation of pronephric nephron tubule development http://purl.obolibrary.org/obo/GO_1900206 regulation of pronephric nephron tubule development Any process that stops, prevents or reduces the frequency, rate or extent of pronephric nephron tubule development. http://purl.obolibrary.org/obo/GO_1900247 regulation of cytoplasmic translational elongation http://purl.obolibrary.org/obo/GO_0006448 regulation of translational elongation Any process that modulates the frequency, rate or extent of cytoplasmic translational elongation. http://purl.obolibrary.org/obo/GO_1900248 negative regulation of cytoplasmic translational elongation http://purl.obolibrary.org/obo/GO_2000766 negative regulation of cytoplasmic translation Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic translational elongation. http://purl.obolibrary.org/obo/GO_1900249 positive regulation of cytoplasmic translational elongation http://purl.obolibrary.org/obo/GO_1900247 regulation of cytoplasmic translational elongation Any process that activates or increases the frequency, rate or extent of cytoplasmic translational elongation. http://purl.obolibrary.org/obo/GO_1900366 negative regulation of defense response to insect http://purl.obolibrary.org/obo/GO_0032102 negative regulation of response to external stimulus Any process that stops, prevents or reduces the frequency, rate or extent of defense response to insect. http://purl.obolibrary.org/obo/GO_1900367 positive regulation of defense response to insect http://purl.obolibrary.org/obo/GO_2000068 regulation of defense response to insect Any process that activates or increases the frequency, rate or extent of defense response to insect. http://purl.obolibrary.org/obo/GO_1900407 regulation of cellular response to oxidative stress http://purl.obolibrary.org/obo/GO_1902882 regulation of response to oxidative stress Any process that modulates the frequency, rate or extent of cellular response to oxidative stress. http://purl.obolibrary.org/obo/GO_1900408 negative regulation of cellular response to oxidative stress http://purl.obolibrary.org/obo/GO_1902883 negative regulation of response to oxidative stress Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to oxidative stress. http://purl.obolibrary.org/obo/GO_1900409 positive regulation of cellular response to oxidative stress http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the frequency, rate or extent of cellular response to oxidative stress. http://purl.obolibrary.org/obo/GO_1900419 regulation of alcohol catabolic process http://purl.obolibrary.org/obo/GO_0009894 regulation of catabolic process Any process that modulates the frequency, rate or extent of alcohol catabolic process within a cell. http://purl.obolibrary.org/obo/GO_1900420 negative regulation of alcohol catabolic process http://purl.obolibrary.org/obo/GO_0009895 negative regulation of catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of alcohol catabolic process within a cell. http://purl.obolibrary.org/obo/GO_1900421 positive regulation of alcohol catabolic process http://purl.obolibrary.org/obo/GO_0009896 positive regulation of catabolic process Any process that activates or increases the frequency, rate or extent of alcohol catabolic process within a cell. http://purl.obolibrary.org/obo/GO_1900449 regulation of glutamate receptor signaling pathway http://purl.obolibrary.org/obo/GO_0009966 regulation of signal transduction Any process that modulates the frequency, rate or extent of glutamate receptor signaling pathway. http://purl.obolibrary.org/obo/GO_1900450 negative regulation of glutamate receptor signaling pathway http://purl.obolibrary.org/obo/GO_1900449 regulation of glutamate receptor signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of glutamate receptor signaling pathway. http://purl.obolibrary.org/obo/GO_1900451 positive regulation of glutamate receptor signaling pathway http://purl.obolibrary.org/obo/GO_1900449 regulation of glutamate receptor signaling pathway Any process that activates or increases the frequency, rate or extent of glutamate receptor signaling pathway. http://purl.obolibrary.org/obo/GO_1900825 regulation of membrane depolarization during cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_0098902 regulation of membrane depolarization during action potential Any process that modulates the frequency, rate or extent of membrane depolarization during a cardiac muscle cell action potential. http://purl.obolibrary.org/obo/GO_1900826 negative regulation of membrane depolarization during cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_1900825 regulation of membrane depolarization during cardiac muscle cell action potential Any process that stops, prevents or reduces the frequency, rate or extent of membrane depolarization during a cardiac muscle cell action potential. http://purl.obolibrary.org/obo/GO_1900827 positive regulation of membrane depolarization during cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_1900825 regulation of membrane depolarization during cardiac muscle cell action potential Any process that activates or increases the frequency, rate or extent of membrane depolarization during a cardiac muscle cell action potential. http://purl.obolibrary.org/obo/GO_1900923 regulation of glycine import across plasma membrane http://purl.obolibrary.org/obo/GO_0010958 regulation of amino acid import across plasma membrane Any process that modulates the frequency, rate or extent of glycine import into a cell. http://purl.obolibrary.org/obo/GO_1900924 negative regulation of glycine import across plasma membrane http://purl.obolibrary.org/obo/GO_1900923 regulation of glycine import across plasma membrane Any process that stops, prevents or reduces the frequency, rate or extent of glycine import into a cell. http://purl.obolibrary.org/obo/GO_1900925 positive regulation of glycine import across plasma membrane http://purl.obolibrary.org/obo/GO_1900923 regulation of glycine import across plasma membrane Any process that activates or increases the frequency, rate or extent of glycine import. http://purl.obolibrary.org/obo/GO_1901017 negative regulation of potassium ion transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0032413 negative regulation of ion transmembrane transporter activity Any process that stops, prevents or reduces the frequency, rate or extent of potassium ion transmembrane transporter activity. http://purl.obolibrary.org/obo/GO_1901031 regulation of response to reactive oxygen species http://purl.obolibrary.org/obo/GO_1902882 regulation of response to oxidative stress Any process that modulates the frequency, rate or extent of response to reactive oxygen species. http://purl.obolibrary.org/obo/GO_1901032 negative regulation of response to reactive oxygen species http://purl.obolibrary.org/obo/GO_1902883 negative regulation of response to oxidative stress Any process that stops, prevents or reduces the frequency, rate or extent of response to reactive oxygen species. http://purl.obolibrary.org/obo/GO_1901033 positive regulation of response to reactive oxygen species http://purl.obolibrary.org/obo/GO_1902884 positive regulation of response to oxidative stress Any process that activates or increases the frequency, rate or extent of response to reactive oxygen species. http://purl.obolibrary.org/obo/GO_1901143 insulin catabolic process http://purl.obolibrary.org/obo/GO_1901142 insulin metabolic process The chemical reactions and pathways resulting in the breakdown of insulin. http://purl.obolibrary.org/obo/GO_1901148 gene expression involved in extracellular matrix organization http://purl.obolibrary.org/obo/GO_0010467 gene expression Any gene expression that is involved in extracellular matrix organization. Gene expression includes both transcription to produce an RNA transcript, and the translation of that mRNA into protein. Protein maturation is included in gene expression when required to form an active form of a product from an inactive precursor form. http://purl.obolibrary.org/obo/GO_1901163 regulation of trophoblast cell migration http://purl.obolibrary.org/obo/GO_0030334 regulation of cell migration Any process that modulates the frequency, rate or extent of trophoblast cell migration. http://purl.obolibrary.org/obo/GO_1901164 negative regulation of trophoblast cell migration http://purl.obolibrary.org/obo/GO_2000242 negative regulation of reproductive process Any process that stops, prevents or reduces the frequency, rate or extent of trophoblast cell migration. http://purl.obolibrary.org/obo/GO_1901165 positive regulation of trophoblast cell migration http://purl.obolibrary.org/obo/GO_2000243 positive regulation of reproductive process Any process that activates or increases the frequency, rate or extent of trophoblast cell migration. http://purl.obolibrary.org/obo/GO_1901166 neural crest cell migration involved in autonomic nervous system development http://purl.obolibrary.org/obo/GO_0001755 neural crest cell migration Any neural crest cell migration that is involved in autonomic nervous system development. http://purl.obolibrary.org/obo/GO_1901190 regulation of formation of translation initiation ternary complex http://purl.obolibrary.org/obo/GO_0043254 regulation of protein-containing complex assembly Any process that modulates the frequency, rate or extent of formation of translation initiation ternary complex. http://purl.obolibrary.org/obo/GO_1901191 negative regulation of formation of translation initiation ternary complex http://purl.obolibrary.org/obo/GO_1901190 regulation of formation of translation initiation ternary complex Any process that stops, prevents or reduces the frequency, rate or extent of formation of translation initiation ternary complex. http://purl.obolibrary.org/obo/GO_1901192 positive regulation of formation of translation initiation ternary complex http://purl.obolibrary.org/obo/GO_1901190 regulation of formation of translation initiation ternary complex Any process that activates or increases the frequency, rate or extent of formation of translation initiation ternary complex. http://purl.obolibrary.org/obo/GO_1901201 regulation of extracellular matrix assembly http://purl.obolibrary.org/obo/GO_1903053 regulation of extracellular matrix organization Any process that modulates the frequency, rate or extent of extracellular matrix assembly. http://purl.obolibrary.org/obo/GO_1901202 negative regulation of extracellular matrix assembly http://purl.obolibrary.org/obo/GO_1901201 regulation of extracellular matrix assembly Any process that stops, prevents or reduces the frequency, rate or extent of extracellular matrix assembly. http://purl.obolibrary.org/obo/GO_1901203 positive regulation of extracellular matrix assembly http://purl.obolibrary.org/obo/GO_0044089 positive regulation of cellular component biogenesis Any process that activates or increases the frequency, rate or extent of extracellular matrix assembly. http://purl.obolibrary.org/obo/GO_1901210 regulation of cardiac chamber formation http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of cardiac chamber formation. http://purl.obolibrary.org/obo/GO_1901211 negative regulation of cardiac chamber formation http://purl.obolibrary.org/obo/GO_1901210 regulation of cardiac chamber formation Any process that stops, prevents or reduces the frequency, rate or extent of cardiac chamber formation. http://purl.obolibrary.org/obo/GO_1901212 positive regulation of cardiac chamber formation http://purl.obolibrary.org/obo/GO_1901221 positive regulation of cardiac chamber morphogenesis Any process that activates or increases the frequency, rate or extent of cardiac chamber formation. http://purl.obolibrary.org/obo/GO_1901219 regulation of cardiac chamber morphogenesis http://purl.obolibrary.org/obo/GO_2000826 regulation of heart morphogenesis Any process that modulates the frequency, rate or extent of cardiac chamber morphogenesis. http://purl.obolibrary.org/obo/GO_1901220 negative regulation of cardiac chamber morphogenesis http://purl.obolibrary.org/obo/GO_1901219 regulation of cardiac chamber morphogenesis Any process that stops, prevents or reduces the frequency, rate or extent of cardiac chamber morphogenesis. http://purl.obolibrary.org/obo/GO_1901221 positive regulation of cardiac chamber morphogenesis http://purl.obolibrary.org/obo/GO_1901219 regulation of cardiac chamber morphogenesis Any process that activates or increases the frequency, rate or extent of cardiac chamber morphogenesis. http://purl.obolibrary.org/obo/GO_1901246 regulation of lung ciliated cell differentiation http://purl.obolibrary.org/obo/GO_0030856 regulation of epithelial cell differentiation Any process that modulates the frequency, rate or extent of lung ciliated cell differentiation. http://purl.obolibrary.org/obo/GO_1901247 negative regulation of lung ciliated cell differentiation http://purl.obolibrary.org/obo/GO_1901246 regulation of lung ciliated cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of lung ciliated cell differentiation. http://purl.obolibrary.org/obo/GO_1901248 positive regulation of lung ciliated cell differentiation http://purl.obolibrary.org/obo/GO_1901246 regulation of lung ciliated cell differentiation Any process that activates or increases the frequency, rate or extent of lung ciliated cell differentiation. http://purl.obolibrary.org/obo/GO_1901249 regulation of lung goblet cell differentiation http://purl.obolibrary.org/obo/GO_0030856 regulation of epithelial cell differentiation Any process that modulates the frequency, rate or extent of lung goblet cell differentiation. http://purl.obolibrary.org/obo/GO_1901250 negative regulation of lung goblet cell differentiation http://purl.obolibrary.org/obo/GO_1901249 regulation of lung goblet cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of lung goblet cell differentiation. http://purl.obolibrary.org/obo/GO_1901379 regulation of potassium ion transmembrane transport http://purl.obolibrary.org/obo/GO_1904062 regulation of monoatomic cation transmembrane transport Any process that modulates the frequency, rate or extent of potassium ion transmembrane transport. http://purl.obolibrary.org/obo/GO_1901380 negative regulation of potassium ion transmembrane transport http://purl.obolibrary.org/obo/GO_1901379 regulation of potassium ion transmembrane transport Any process that stops, prevents or reduces the frequency, rate or extent of potassium ion transmembrane transport. http://purl.obolibrary.org/obo/GO_1901381 positive regulation of potassium ion transmembrane transport http://purl.obolibrary.org/obo/GO_1901379 regulation of potassium ion transmembrane transport Any process that activates or increases the frequency, rate or extent of potassium ion transmembrane transport. http://purl.obolibrary.org/obo/GO_1901858 regulation of mitochondrial DNA metabolic process http://purl.obolibrary.org/obo/GO_0051052 regulation of DNA metabolic process Any process that modulates the frequency, rate or extent of mitochondrial DNA metabolic process. http://purl.obolibrary.org/obo/GO_1901859 negative regulation of mitochondrial DNA metabolic process http://purl.obolibrary.org/obo/GO_1901858 regulation of mitochondrial DNA metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial DNA metabolic process. http://purl.obolibrary.org/obo/GO_1901860 positive regulation of mitochondrial DNA metabolic process http://purl.obolibrary.org/obo/GO_0010821 regulation of mitochondrion organization Any process that activates or increases the frequency, rate or extent of mitochondrial DNA metabolic process. http://purl.obolibrary.org/obo/GO_1901888 regulation of cell junction assembly http://purl.obolibrary.org/obo/GO_0051128 regulation of cellular component organization Any process that modulates the frequency, rate or extent of cell junction assembly. http://purl.obolibrary.org/obo/GO_1901950 dense core granule transport http://purl.obolibrary.org/obo/GO_0032253 dense core granule localization The directed movement a dense core granule within a cell. http://purl.obolibrary.org/obo/GO_1902622 regulation of neutrophil migration http://purl.obolibrary.org/obo/GO_0002685 regulation of leukocyte migration Any process that modulates the frequency, rate or extent of neutrophil migration. http://purl.obolibrary.org/obo/GO_1902623 negative regulation of neutrophil migration http://purl.obolibrary.org/obo/GO_1902622 regulation of neutrophil migration Any process that stops, prevents or reduces the frequency, rate or extent of neutrophil migration. http://purl.obolibrary.org/obo/GO_1902624 positive regulation of neutrophil migration http://purl.obolibrary.org/obo/GO_1902622 regulation of neutrophil migration Any process that activates or increases the frequency, rate or extent of neutrophil migration. http://purl.obolibrary.org/obo/GO_1902656 calcium ion import into cytosol http://purl.obolibrary.org/obo/GO_0006816 calcium ion transport The directed movement of calcium ion into a cytosol. http://purl.obolibrary.org/obo/GO_1902882 regulation of response to oxidative stress http://purl.obolibrary.org/obo/GO_0080134 regulation of response to stress Any process that modulates the frequency, rate or extent of response to oxidative stress. http://purl.obolibrary.org/obo/GO_1902883 negative regulation of response to oxidative stress http://purl.obolibrary.org/obo/GO_1902882 regulation of response to oxidative stress Any process that stops, prevents or reduces the frequency, rate or extent of response to oxidative stress. http://purl.obolibrary.org/obo/GO_1902884 positive regulation of response to oxidative stress http://purl.obolibrary.org/obo/GO_1902882 regulation of response to oxidative stress Any process that activates or increases the frequency, rate or extent of response to oxidative stress. http://purl.obolibrary.org/obo/GO_1903011 negative regulation of bone development http://purl.obolibrary.org/obo/GO_1903010 regulation of bone development Any process that stops, prevents or reduces the frequency, rate or extent of bone development. http://purl.obolibrary.org/obo/GO_1903012 positive regulation of bone development http://purl.obolibrary.org/obo/GO_1903010 regulation of bone development Any process that activates or increases the frequency, rate or extent of bone development. http://purl.obolibrary.org/obo/GO_1903076 regulation of protein localization to plasma membrane http://purl.obolibrary.org/obo/GO_1904375 regulation of protein localization to cell periphery Any process that modulates the frequency, rate or extent of protein localization to plasma membrane. http://purl.obolibrary.org/obo/GO_1903077 negative regulation of protein localization to plasma membrane http://purl.obolibrary.org/obo/GO_1904376 negative regulation of protein localization to cell periphery Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to plasma membrane. http://purl.obolibrary.org/obo/GO_1903078 positive regulation of protein localization to plasma membrane http://purl.obolibrary.org/obo/GO_1904377 positive regulation of protein localization to cell periphery Any process that activates or increases the frequency, rate or extent of protein localization to plasma membrane. http://purl.obolibrary.org/obo/GO_1903251 multi-ciliated epithelial cell differentiation http://purl.obolibrary.org/obo/GO_0002065 columnar/cuboidal epithelial cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a multi-ciliated epithelial cell. http://purl.obolibrary.org/obo/GO_1903327 negative regulation of tRNA metabolic process http://purl.obolibrary.org/obo/GO_1903326 regulation of tRNA metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of tRNA metabolic process. http://purl.obolibrary.org/obo/GO_1903335 regulation of vacuolar transport http://purl.obolibrary.org/obo/GO_0032386 regulation of intracellular transport Any process that modulates the frequency, rate or extent of vacuolar transport. http://purl.obolibrary.org/obo/GO_1903336 negative regulation of vacuolar transport http://purl.obolibrary.org/obo/GO_1903335 regulation of vacuolar transport Any process that stops, prevents or reduces the frequency, rate or extent of vacuolar transport. http://purl.obolibrary.org/obo/GO_1903337 positive regulation of vacuolar transport http://purl.obolibrary.org/obo/GO_1903335 regulation of vacuolar transport Any process that activates or increases the frequency, rate or extent of vacuolar transport. http://purl.obolibrary.org/obo/GO_1903358 regulation of Golgi organization http://purl.obolibrary.org/obo/GO_0033043 regulation of organelle organization Any process that modulates the frequency, rate or extent of Golgi organization. http://purl.obolibrary.org/obo/GO_1903441 protein localization to ciliary membrane http://purl.obolibrary.org/obo/GO_0061512 protein localization to cilium A process in which a protein is transported to, or maintained in, a location within a ciliary membrane. http://purl.obolibrary.org/obo/GO_1903539 protein localization to postsynaptic membrane http://purl.obolibrary.org/obo/GO_0062237 protein localization to postsynapse A process in which a protein is transported to, or maintained in, a location within a postsynaptic membrane. http://purl.obolibrary.org/obo/GO_1903540 establishment of protein localization to postsynaptic membrane http://purl.obolibrary.org/obo/GO_0090150 establishment of protein localization to membrane The directed movement of a protein to a specific location in a postsynaptic membrane. http://purl.obolibrary.org/obo/GO_1903747 regulation of protein localization to mitochondrion http://purl.obolibrary.org/obo/GO_0032880 regulation of protein localization Any process that modulates the frequency, rate or extent of protein localization to mitochondrion. http://purl.obolibrary.org/obo/GO_1903749 positive regulation of protein localization to mitochondrion http://purl.obolibrary.org/obo/GO_1903829 positive regulation of protein localization Any process that activates or increases the frequency, rate or extent of protein localization to mitochondrion. http://purl.obolibrary.org/obo/GO_1903779 regulation of cardiac conduction http://purl.obolibrary.org/obo/GO_0008016 regulation of heart contraction Any process that modulates the frequency, rate or extent of cardiac conduction. http://purl.obolibrary.org/obo/GO_1903810 L-histidine import across plasma membrane http://purl.obolibrary.org/obo/GO_0089718 amino acid import across plasma membrane The directed movement of L-histidine from outside of a cell, across the plasma membrane and into the cytosol. http://purl.obolibrary.org/obo/GO_1903829 positive regulation of protein localization http://purl.obolibrary.org/obo/GO_0032880 regulation of protein localization Any process that activates or increases the frequency, rate or extent of a protein localization. http://purl.obolibrary.org/obo/GO_1903831 signal transduction involved in cellular response to ammonium ion http://purl.obolibrary.org/obo/GO_0007165 signal transduction Any signal transduction that is involved in cellular response to ammonium ion. http://purl.obolibrary.org/obo/GO_1903975 regulation of glial cell migration http://purl.obolibrary.org/obo/GO_0030334 regulation of cell migration Any process that modulates the frequency, rate or extent of glial cell migration. http://purl.obolibrary.org/obo/GO_1903977 positive regulation of glial cell migration http://purl.obolibrary.org/obo/GO_1903975 regulation of glial cell migration Any process that activates or increases the frequency, rate or extent of glial cell migration. http://purl.obolibrary.org/obo/GO_1904587 response to glycoprotein http://purl.obolibrary.org/obo/GO_1901700 response to oxygen-containing compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycoprotein stimulus. http://purl.obolibrary.org/obo/GO_1904688 regulation of cytoplasmic translational initiation http://purl.obolibrary.org/obo/GO_2000765 regulation of cytoplasmic translation Any process that modulates the frequency, rate or extent of cytoplasmic translational initiation. http://purl.obolibrary.org/obo/GO_1904689 negative regulation of cytoplasmic translational initiation http://purl.obolibrary.org/obo/GO_1904688 regulation of cytoplasmic translational initiation Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic translational initiation. http://purl.obolibrary.org/obo/GO_1904690 positive regulation of cytoplasmic translational initiation http://purl.obolibrary.org/obo/GO_1904688 regulation of cytoplasmic translational initiation Any process that activates or increases the frequency, rate or extent of cytoplasmic translational initiation. http://purl.obolibrary.org/obo/GO_1904861 excitatory synapse assembly http://purl.obolibrary.org/obo/GO_0007416 synapse assembly The aggregation, arrangement and bonding together of a set of components to form an excitatory synapse. http://purl.obolibrary.org/obo/GO_1904970 brush border assembly http://purl.obolibrary.org/obo/GO_0022607 cellular component assembly The aggregation, arrangement and bonding together of adjacent microvilli through the formation of Ca(2+)-dependent adhesion links between them, forming a brush border. http://purl.obolibrary.org/obo/GO_1905270 Meynert cell differentiation http://purl.obolibrary.org/obo/GO_0021895 cerebral cortex neuron differentiation The process in which a relatively unspecialized cell acquires the specialized features of a Meynert cell. http://purl.obolibrary.org/obo/GO_1905383 protein localization to presynapse http://purl.obolibrary.org/obo/GO_0035418 protein localization to synapse A process in which a protein is transported to, or maintained in, a location within a presynapse. http://purl.obolibrary.org/obo/GO_1905475 regulation of protein localization to membrane http://purl.obolibrary.org/obo/GO_0060341 regulation of cellular localization Any process that modulates the frequency, rate or extent of protein localization to membrane. http://purl.obolibrary.org/obo/GO_1905476 negative regulation of protein localization to membrane http://purl.obolibrary.org/obo/GO_1903828 negative regulation of protein localization Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to membrane. http://purl.obolibrary.org/obo/GO_1905477 positive regulation of protein localization to membrane http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the frequency, rate or extent of protein localization to membrane. http://purl.obolibrary.org/obo/GO_1990182 exosomal secretion http://purl.obolibrary.org/obo/GO_0051650 establishment of vesicle localization The process whereby a membrane-bounded vesicle is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. http://purl.obolibrary.org/obo/GO_1990716 axonemal central apparatus http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure Part of the 9+2 axoneme, that occurs in most motile cilia, consisting of the pair of two single central microtubules and their associated structures which include the central pair projections, the central pair bridges linking the two tubules, and the central pair caps which are attached to the distal or plus ends of the microtubules. http://purl.obolibrary.org/obo/GO_1990719 C1 axonemal microtubule http://purl.obolibrary.org/obo/GO_0005879 axonemal microtubule One of two microtubules present in the axonemal central pair. It is distinguishable from the C2 axonemal microtubule (also called C2 tubule) by the presence of differing protein components of the projections. http://purl.obolibrary.org/obo/GO_1990720 C2 axonemal microtubule http://purl.obolibrary.org/obo/GO_0005879 axonemal microtubule One of two microtubules present in the axonemal central pair. It is distinguishable from the C1 axonemal microtubule (also called C1 tubule) by the presence of differing protein components of the projections. http://purl.obolibrary.org/obo/GO_2000068 regulation of defense response to insect http://purl.obolibrary.org/obo/GO_0031347 regulation of defense response Any process that modulates the frequency, rate or extent of defense response to insect. http://purl.obolibrary.org/obo/GO_2000282 regulation of amino acid biosynthetic process http://purl.obolibrary.org/obo/GO_0009889 regulation of biosynthetic process Any process that modulates the frequency, rate or extent of cellular amino acid biosynthetic process. http://purl.obolibrary.org/obo/GO_2000283 negative regulation of amino acid biosynthetic process http://purl.obolibrary.org/obo/GO_0009890 negative regulation of biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of an amino acid biosynthetic process. http://purl.obolibrary.org/obo/GO_2000284 positive regulation of amino acid biosynthetic process http://purl.obolibrary.org/obo/GO_0009891 positive regulation of biosynthetic process Any process that activates or increases the frequency, rate or extent of cellular amino acid biosynthetic process. http://purl.obolibrary.org/obo/GO_2000380 regulation of mesoderm development http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of mesoderm development. http://purl.obolibrary.org/obo/GO_2000381 negative regulation of mesoderm development http://purl.obolibrary.org/obo/GO_2000380 regulation of mesoderm development Any process that stops, prevents or reduces the frequency, rate or extent of mesoderm development. http://purl.obolibrary.org/obo/GO_2000382 positive regulation of mesoderm development http://purl.obolibrary.org/obo/GO_2000380 regulation of mesoderm development Any process that activates or increases the frequency, rate or extent of mesoderm development. http://purl.obolibrary.org/obo/GO_2000425 regulation of apoptotic cell clearance http://purl.obolibrary.org/obo/GO_0050764 regulation of phagocytosis Any process that modulates the frequency, rate or extent of apoptotic cell clearance. http://purl.obolibrary.org/obo/GO_2000426 negative regulation of apoptotic cell clearance http://purl.obolibrary.org/obo/GO_2000425 regulation of apoptotic cell clearance Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic cell clearance. http://purl.obolibrary.org/obo/GO_2000427 positive regulation of apoptotic cell clearance http://purl.obolibrary.org/obo/GO_2000425 regulation of apoptotic cell clearance Any process that activates or increases the frequency, rate or extent of apoptotic cell clearance. http://purl.obolibrary.org/obo/GO_2000523 regulation of T cell costimulation http://purl.obolibrary.org/obo/GO_0050863 regulation of T cell activation Any process that modulates the frequency, rate or extent of T cell costimulation. http://purl.obolibrary.org/obo/GO_2000524 negative regulation of T cell costimulation http://purl.obolibrary.org/obo/GO_2000523 regulation of T cell costimulation Any process that stops, prevents or reduces the frequency, rate or extent of T cell costimulation. http://purl.obolibrary.org/obo/GO_2000525 positive regulation of T cell costimulation http://purl.obolibrary.org/obo/GO_2000523 regulation of T cell costimulation Any process that activates or increases the frequency, rate or extent of T cell costimulation. http://purl.obolibrary.org/obo/GO_2000765 regulation of cytoplasmic translation http://purl.obolibrary.org/obo/GO_0006417 regulation of translation Any process that modulates the frequency, rate or extent of cytoplasmic translation. http://purl.obolibrary.org/obo/GO_2000766 negative regulation of cytoplasmic translation http://purl.obolibrary.org/obo/GO_2000765 regulation of cytoplasmic translation Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic translation. http://purl.obolibrary.org/obo/GO_2000767 positive regulation of cytoplasmic translation http://purl.obolibrary.org/obo/GO_0045727 positive regulation of translation Any process that activates or increases the frequency, rate or extent of cytoplasmic translation. http://purl.obolibrary.org/obo/GO_2001233 regulation of apoptotic signaling pathway http://purl.obolibrary.org/obo/GO_0042981 regulation of apoptotic process Any process that modulates the frequency, rate or extent of apoptotic signaling pathway. http://purl.obolibrary.org/obo/GO_2001234 negative regulation of apoptotic signaling pathway http://purl.obolibrary.org/obo/GO_2001233 regulation of apoptotic signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic signaling pathway. http://purl.obolibrary.org/obo/GO_2001235 positive regulation of apoptotic signaling pathway http://purl.obolibrary.org/obo/GO_0043065 positive regulation of apoptotic process Any process that activates or increases the frequency, rate or extent of apoptotic signaling pathway. http://purl.obolibrary.org/obo/GO_1901251 positive regulation of lung goblet cell differentiation http://purl.obolibrary.org/obo/GO_1901249 regulation of lung goblet cell differentiation Any process that activates or increases the frequency, rate or extent of lung goblet cell differentiation. http://purl.obolibrary.org/obo/GO_1901317 regulation of flagellated sperm motility http://purl.obolibrary.org/obo/GO_0060295 regulation of cilium movement involved in cell motility Any process that modulates the frequency, rate or extent of flagellated sperm motility. http://purl.obolibrary.org/obo/GO_1901318 negative regulation of flagellated sperm motility http://purl.obolibrary.org/obo/GO_2000242 negative regulation of reproductive process Any process that stops, prevents or reduces the frequency, rate or extent of flagellated sperm motility. http://purl.obolibrary.org/obo/GO_1901329 regulation of odontoblast differentiation http://purl.obolibrary.org/obo/GO_0030856 regulation of epithelial cell differentiation Any process that modulates the frequency, rate or extent of odontoblast differentiation. http://purl.obolibrary.org/obo/GO_1901330 negative regulation of odontoblast differentiation http://purl.obolibrary.org/obo/GO_1901329 regulation of odontoblast differentiation Any process that stops, prevents or reduces the frequency, rate or extent of odontoblast differentiation. http://purl.obolibrary.org/obo/GO_1901331 positive regulation of odontoblast differentiation http://purl.obolibrary.org/obo/GO_1901329 regulation of odontoblast differentiation Any process that activates or increases the frequency, rate or extent of odontoblast differentiation. http://purl.obolibrary.org/obo/GO_1901382 regulation of chorionic trophoblast cell proliferation http://purl.obolibrary.org/obo/GO_0042127 regulation of cell population proliferation Any process that modulates the frequency, rate or extent of chorionic trophoblast cell proliferation. http://purl.obolibrary.org/obo/GO_1901383 negative regulation of chorionic trophoblast cell proliferation http://purl.obolibrary.org/obo/GO_0008285 negative regulation of cell population proliferation Any process that stops, prevents or reduces the frequency, rate or extent of chorionic trophoblast cell proliferation. http://purl.obolibrary.org/obo/GO_1901384 positive regulation of chorionic trophoblast cell proliferation http://purl.obolibrary.org/obo/GO_1901382 regulation of chorionic trophoblast cell proliferation Any process that activates or increases the frequency, rate or extent of chorionic trophoblast cell proliferation. http://purl.obolibrary.org/obo/GO_1901386 negative regulation of voltage-gated calcium channel activity http://purl.obolibrary.org/obo/GO_1901385 regulation of voltage-gated calcium channel activity Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated calcium channel activity. http://purl.obolibrary.org/obo/GO_1901387 positive regulation of voltage-gated calcium channel activity http://purl.obolibrary.org/obo/GO_1901385 regulation of voltage-gated calcium channel activity Any process that activates or increases the frequency, rate or extent of voltage-gated calcium channel activity. http://purl.obolibrary.org/obo/GO_1901472 regulation of Golgi calcium ion export http://purl.obolibrary.org/obo/GO_0051279 regulation of release of sequestered calcium ion into cytosol Any process that modulates the frequency, rate or extent of Golgi calcium ion export. http://purl.obolibrary.org/obo/GO_1901490 regulation of lymphangiogenesis http://purl.obolibrary.org/obo/GO_0022603 regulation of anatomical structure morphogenesis Any process that modulates the frequency, rate or extent of lymphangiogenesis. http://purl.obolibrary.org/obo/GO_1901491 negative regulation of lymphangiogenesis http://purl.obolibrary.org/obo/GO_1901490 regulation of lymphangiogenesis Any process that stops, prevents or reduces the frequency, rate or extent of lymphangiogenesis. http://purl.obolibrary.org/obo/GO_1901492 positive regulation of lymphangiogenesis http://purl.obolibrary.org/obo/GO_1901490 regulation of lymphangiogenesis Any process that activates or increases the frequency, rate or extent of lymphangiogenesis. http://purl.obolibrary.org/obo/GO_1901509 regulation of endothelial tube morphogenesis http://purl.obolibrary.org/obo/GO_1905330 regulation of morphogenesis of an epithelium Any process that modulates the frequency, rate or extent of endothelial tube morphogenesis. http://purl.obolibrary.org/obo/GO_1901532 regulation of hematopoietic progenitor cell differentiation http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the frequency, rate or extent of hematopoietic progenitor cell differentiation. http://purl.obolibrary.org/obo/GO_1901533 negative regulation of hematopoietic progenitor cell differentiation http://purl.obolibrary.org/obo/GO_1901532 regulation of hematopoietic progenitor cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic progenitor cell differentiation. http://purl.obolibrary.org/obo/GO_1901534 positive regulation of hematopoietic progenitor cell differentiation http://purl.obolibrary.org/obo/GO_0045597 positive regulation of cell differentiation Any process that activates or increases the frequency, rate or extent of hematopoietic progenitor cell differentiation. http://purl.obolibrary.org/obo/GO_1901550 regulation of endothelial cell development http://purl.obolibrary.org/obo/GO_0060284 regulation of cell development Any process that modulates the frequency, rate or extent of endothelial cell development. http://purl.obolibrary.org/obo/GO_1901551 negative regulation of endothelial cell development http://purl.obolibrary.org/obo/GO_0010721 negative regulation of cell development Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell development. http://purl.obolibrary.org/obo/GO_1901552 positive regulation of endothelial cell development http://purl.obolibrary.org/obo/GO_0010720 positive regulation of cell development Any process that activates or increases the frequency, rate or extent of endothelial cell development. http://purl.obolibrary.org/obo/GO_1901588 dendritic microtubule http://purl.obolibrary.org/obo/GO_0005874 microtubule Any microtubule in a dendrite, a neuron projection. http://purl.obolibrary.org/obo/GO_1901589 axon microtubule bundle http://purl.obolibrary.org/obo/GO_0097427 microtubule bundle An arrangement of closely apposed microtubules running parallel to each other in the axon hillock and initial segment. http://purl.obolibrary.org/obo/GO_1901608 regulation of vesicle transport along microtubule http://purl.obolibrary.org/obo/GO_1902513 regulation of organelle transport along microtubule Any process that modulates the frequency, rate or extent of vesicle transport along microtubule. http://purl.obolibrary.org/obo/GO_1901609 negative regulation of vesicle transport along microtubule http://purl.obolibrary.org/obo/GO_1901608 regulation of vesicle transport along microtubule Any process that stops, prevents or reduces the frequency, rate or extent of vesicle transport along microtubule. http://purl.obolibrary.org/obo/GO_1901610 positive regulation of vesicle transport along microtubule http://purl.obolibrary.org/obo/GO_1901608 regulation of vesicle transport along microtubule Any process that activates or increases the frequency, rate or extent of vesicle transport along microtubule. http://purl.obolibrary.org/obo/GO_1901613 negative regulation of terminal button organization http://purl.obolibrary.org/obo/GO_0051129 negative regulation of cellular component organization Any process that stops, prevents or reduces the frequency, rate or extent of terminal button organization. http://purl.obolibrary.org/obo/GO_1901614 positive regulation of terminal button organization http://purl.obolibrary.org/obo/GO_0051130 positive regulation of cellular component organization Any process that activates or increases the frequency, rate or extent of terminal button organization. http://purl.obolibrary.org/obo/GO_1901624 negative regulation of lymphocyte chemotaxis http://purl.obolibrary.org/obo/GO_1901623 regulation of lymphocyte chemotaxis Any process that stops, prevents or reduces the frequency, rate or extent of lymphocyte chemotaxis. http://purl.obolibrary.org/obo/GO_1901626 regulation of postsynaptic membrane organization http://purl.obolibrary.org/obo/GO_0051128 regulation of cellular component organization Any process that modulates the frequency, rate or extent of postsynaptic membrane organization. http://purl.obolibrary.org/obo/GO_1901627 negative regulation of postsynaptic membrane organization http://purl.obolibrary.org/obo/GO_1905809 negative regulation of synapse organization Any process that stops, prevents or reduces the frequency, rate or extent of postsynaptic membrane organization. http://purl.obolibrary.org/obo/GO_1901628 positive regulation of postsynaptic membrane organization http://purl.obolibrary.org/obo/GO_0051130 positive regulation of cellular component organization Any process that activates or increases the frequency, rate or extent of postsynaptic membrane organization. http://purl.obolibrary.org/obo/GO_1901645 regulation of synoviocyte proliferation http://purl.obolibrary.org/obo/GO_0050678 regulation of epithelial cell proliferation Any process that modulates the frequency, rate or extent of synoviocyte proliferation. http://purl.obolibrary.org/obo/GO_1901646 negative regulation of synoviocyte proliferation http://purl.obolibrary.org/obo/GO_1901645 regulation of synoviocyte proliferation Any process that stops, prevents or reduces the frequency, rate or extent of synoviocyte proliferation. http://purl.obolibrary.org/obo/GO_1901647 positive regulation of synoviocyte proliferation http://purl.obolibrary.org/obo/GO_1901645 regulation of synoviocyte proliferation Any process that activates or increases the frequency, rate or extent of synoviocyte proliferation. http://purl.obolibrary.org/obo/GO_1901691 proton binding http://purl.obolibrary.org/obo/GO_0043169 cation binding Binding to proton. http://purl.obolibrary.org/obo/GO_1901692 regulation of compound eye retinal cell apoptotic process http://purl.obolibrary.org/obo/GO_0042981 regulation of apoptotic process Any process that modulates the frequency, rate or extent of compound eye retinal cell apoptotic process. http://purl.obolibrary.org/obo/GO_1901693 negative regulation of compound eye retinal cell apoptotic process http://purl.obolibrary.org/obo/GO_1901692 regulation of compound eye retinal cell apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of compound eye retinal cell apoptotic process. http://purl.obolibrary.org/obo/GO_1901706 mesenchymal cell differentiation involved in bone development http://purl.obolibrary.org/obo/GO_0048762 mesenchymal cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of bone as it progresses from its formation to the mature state. http://purl.obolibrary.org/obo/GO_1901715 regulation of gamma-aminobutyric acid catabolic process http://purl.obolibrary.org/obo/GO_0009894 regulation of catabolic process Any process that modulates the frequency, rate or extent of gamma-aminobutyric acid catabolic process. http://purl.obolibrary.org/obo/GO_1901716 negative regulation of gamma-aminobutyric acid catabolic process http://purl.obolibrary.org/obo/GO_0009895 negative regulation of catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of gamma-aminobutyric acid catabolic process. http://purl.obolibrary.org/obo/GO_1901717 positive regulation of gamma-aminobutyric acid catabolic process http://purl.obolibrary.org/obo/GO_0009896 positive regulation of catabolic process Any process that activates or increases the frequency, rate or extent of gamma-aminobutyric acid catabolic process. http://purl.obolibrary.org/obo/GO_1901826 zeaxanthin catabolic process http://purl.obolibrary.org/obo/GO_0016124 xanthophyll catabolic process The chemical reactions and pathways resulting in the breakdown of zeaxanthin. http://purl.obolibrary.org/obo/GO_1901827 zeaxanthin biosynthetic process http://purl.obolibrary.org/obo/GO_0016123 xanthophyll biosynthetic process The chemical reactions and pathways resulting in the formation of zeaxanthin. http://purl.obolibrary.org/obo/GO_1901876 regulation of calcium ion binding http://purl.obolibrary.org/obo/GO_0051098 regulation of binding Any process that modulates the frequency, rate or extent of calcium ion binding. http://purl.obolibrary.org/obo/GO_1901951 regulation of anterograde dense core granule transport http://purl.obolibrary.org/obo/GO_1904809 regulation of dense core granule transport Any process that modulates the frequency, rate or extent of anterograde dense core granule transport. http://purl.obolibrary.org/obo/GO_1901952 negative regulation of anterograde dense core granule transport http://purl.obolibrary.org/obo/GO_1904810 negative regulation of dense core granule transport Any process that stops, prevents or reduces the frequency, rate or extent of anterograde dense core granule transport. http://purl.obolibrary.org/obo/GO_1901953 positive regulation of anterograde dense core granule transport http://purl.obolibrary.org/obo/GO_1904811 positive regulation of dense core granule transport Any process that activates or increases the frequency, rate or extent of anterograde dense core granule transport. http://purl.obolibrary.org/obo/GO_1901954 regulation of retrograde dense core granule transport http://purl.obolibrary.org/obo/GO_2001017 regulation of retrograde axon cargo transport Any process that modulates the frequency, rate or extent of retrograde dense core granule transport. http://purl.obolibrary.org/obo/GO_1901955 negative regulation of retrograde dense core granule transport http://purl.obolibrary.org/obo/GO_2001018 negative regulation of retrograde axon cargo transport Any process that stops, prevents or reduces the frequency, rate or extent of retrograde dense core granule transport. http://purl.obolibrary.org/obo/GO_1901956 positive regulation of retrograde dense core granule transport http://purl.obolibrary.org/obo/GO_2001019 positive regulation of retrograde axon cargo transport Any process that activates or increases the frequency, rate or extent of retrograde dense core granule transport. http://purl.obolibrary.org/obo/GO_1902018 negative regulation of cilium assembly http://purl.obolibrary.org/obo/GO_0120033 negative regulation of plasma membrane bounded cell projection assembly Any process that stops, prevents or reduces the frequency, rate or extent of cilium assembly. http://purl.obolibrary.org/obo/GO_1902020 negative regulation of cilium-dependent cell motility http://purl.obolibrary.org/obo/GO_1902019 regulation of cilium-dependent cell motility Any process that stops, prevents or reduces the frequency, rate or extent of cilium-dependent cell motility. http://purl.obolibrary.org/obo/GO_1902033 regulation of hematopoietic stem cell proliferation http://purl.obolibrary.org/obo/GO_0072091 regulation of stem cell proliferation Any process that modulates the frequency, rate or extent of hematopoietic stem cell proliferation. http://purl.obolibrary.org/obo/GO_1902034 negative regulation of hematopoietic stem cell proliferation http://purl.obolibrary.org/obo/GO_1902033 regulation of hematopoietic stem cell proliferation Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic stem cell proliferation. http://purl.obolibrary.org/obo/GO_1902035 positive regulation of hematopoietic stem cell proliferation http://purl.obolibrary.org/obo/GO_1902033 regulation of hematopoietic stem cell proliferation Any process that activates or increases the frequency, rate or extent of hematopoietic stem cell proliferation. http://purl.obolibrary.org/obo/GO_1902036 regulation of hematopoietic stem cell differentiation http://purl.obolibrary.org/obo/GO_1901532 regulation of hematopoietic progenitor cell differentiation Any process that modulates the frequency, rate or extent of hematopoietic stem cell differentiation. http://purl.obolibrary.org/obo/GO_1902037 negative regulation of hematopoietic stem cell differentiation http://purl.obolibrary.org/obo/GO_1902036 regulation of hematopoietic stem cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic stem cell differentiation. http://purl.obolibrary.org/obo/GO_1902038 positive regulation of hematopoietic stem cell differentiation http://purl.obolibrary.org/obo/GO_1902036 regulation of hematopoietic stem cell differentiation Any process that activates or increases the frequency, rate or extent of hematopoietic stem cell differentiation. http://purl.obolibrary.org/obo/GO_1902065 response to L-glutamate http://purl.obolibrary.org/obo/GO_1901698 response to nitrogen compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an L-glutamate stimulus. http://purl.obolibrary.org/obo/GO_1902076 regulation of lateral motor column neuron migration http://purl.obolibrary.org/obo/GO_1905483 regulation of motor neuron migration Any process that modulates the frequency, rate or extent of lateral motor column neuron migration. http://purl.obolibrary.org/obo/GO_1902077 negative regulation of lateral motor column neuron migration http://purl.obolibrary.org/obo/GO_1905484 negative regulation of motor neuron migration Any process that stops, prevents or reduces the frequency, rate or extent of lateral motor column neuron migration. http://purl.obolibrary.org/obo/GO_1902078 positive regulation of lateral motor column neuron migration http://purl.obolibrary.org/obo/GO_1905485 positive regulation of motor neuron migration Any process that activates or increases the frequency, rate or extent of lateral motor column neuron migration. http://purl.obolibrary.org/obo/GO_1902172 regulation of keratinocyte apoptotic process http://purl.obolibrary.org/obo/GO_1904035 regulation of epithelial cell apoptotic process Any process that modulates the frequency, rate or extent of keratinocyte apoptotic process. http://purl.obolibrary.org/obo/GO_1902173 negative regulation of keratinocyte apoptotic process http://purl.obolibrary.org/obo/GO_1904036 negative regulation of epithelial cell apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of keratinocyte apoptotic process. http://purl.obolibrary.org/obo/GO_1902174 positive regulation of keratinocyte apoptotic process http://purl.obolibrary.org/obo/GO_1904037 positive regulation of epithelial cell apoptotic process Any process that activates or increases the frequency, rate or extent of keratinocyte apoptotic process. http://purl.obolibrary.org/obo/GO_1902211 regulation of prolactin signaling pathway http://purl.obolibrary.org/obo/GO_0001959 regulation of cytokine-mediated signaling pathway Any process that modulates the frequency, rate or extent of prolactin signaling pathway. http://purl.obolibrary.org/obo/GO_1902212 negative regulation of prolactin signaling pathway http://purl.obolibrary.org/obo/GO_1902211 regulation of prolactin signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of prolactin signaling pathway. http://purl.obolibrary.org/obo/GO_1902213 positive regulation of prolactin signaling pathway http://purl.obolibrary.org/obo/GO_1902211 regulation of prolactin signaling pathway Any process that activates or increases the frequency, rate or extent of prolactin signaling pathway. http://purl.obolibrary.org/obo/GO_1902217 erythrocyte apoptotic process http://purl.obolibrary.org/obo/GO_0033028 myeloid cell apoptotic process Any apoptotic process in an erythrocyte. http://purl.obolibrary.org/obo/GO_1902250 regulation of erythrocyte apoptotic process http://purl.obolibrary.org/obo/GO_0033032 regulation of myeloid cell apoptotic process Any process that modulates the frequency, rate or extent of erythrocyte apoptotic process. http://purl.obolibrary.org/obo/GO_1902251 negative regulation of erythrocyte apoptotic process http://purl.obolibrary.org/obo/GO_1902250 regulation of erythrocyte apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of erythrocyte apoptotic process. http://purl.obolibrary.org/obo/GO_1902252 positive regulation of erythrocyte apoptotic process http://purl.obolibrary.org/obo/GO_1902250 regulation of erythrocyte apoptotic process Any process that activates or increases the frequency, rate or extent of erythrocyte apoptotic process. http://purl.obolibrary.org/obo/GO_1902256 regulation of apoptotic process involved in outflow tract morphogenesis http://purl.obolibrary.org/obo/GO_1904748 regulation of apoptotic process involved in development Any process that modulates the frequency, rate or extent of apoptotic process involved in outflow tract morphogenesis. http://purl.obolibrary.org/obo/GO_1902257 negative regulation of apoptotic process involved in outflow tract morphogenesis http://purl.obolibrary.org/obo/GO_1902338 negative regulation of apoptotic process involved in morphogenesis Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in outflow tract morphogenesis. http://purl.obolibrary.org/obo/GO_1902262 apoptotic process involved in blood vessel morphogenesis http://purl.obolibrary.org/obo/GO_0060561 apoptotic process involved in morphogenesis Any apoptotic process that is involved in blood vessel morphogenesis. http://purl.obolibrary.org/obo/GO_1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization http://purl.obolibrary.org/obo/GO_0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of a ventricular cardiomyocyte contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. http://purl.obolibrary.org/obo/GO_1902305 regulation of sodium ion transmembrane transport http://purl.obolibrary.org/obo/GO_1904062 regulation of monoatomic cation transmembrane transport Any process that modulates the frequency, rate or extent of sodium ion transmembrane transport. http://purl.obolibrary.org/obo/GO_1902306 negative regulation of sodium ion transmembrane transport http://purl.obolibrary.org/obo/GO_0010766 negative regulation of sodium ion transport Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion transmembrane transport. http://purl.obolibrary.org/obo/GO_1902307 positive regulation of sodium ion transmembrane transport http://purl.obolibrary.org/obo/GO_0010765 positive regulation of sodium ion transport Any process that activates or increases the frequency, rate or extent of sodium ion transmembrane transport. http://purl.obolibrary.org/obo/GO_1902340 negative regulation of chromosome condensation http://purl.obolibrary.org/obo/GO_0060623 regulation of chromosome condensation Any process that stops, prevents or reduces the frequency, rate or extent of chromosome condensation. http://purl.obolibrary.org/obo/GO_1902362 melanocyte apoptotic process http://purl.obolibrary.org/obo/GO_0006915 apoptotic process Any apoptotic process in a melanocyte, the main structural component of the epidermis. http://purl.obolibrary.org/obo/GO_1902396 protein localization to bicellular tight junction http://purl.obolibrary.org/obo/GO_0150105 protein localization to cell-cell junction A process in which a protein is transported to, or maintained in, a location within a bicellular tight junction. http://purl.obolibrary.org/obo/GO_1902427 regulation of water channel activity http://purl.obolibrary.org/obo/GO_0022898 regulation of transmembrane transporter activity Any process that modulates the frequency, rate or extent of water channel activity. http://purl.obolibrary.org/obo/GO_1902455 negative regulation of stem cell population maintenance http://purl.obolibrary.org/obo/GO_2000036 regulation of stem cell population maintenance Any process that stops, prevents or reduces the frequency, rate or extent of stem cell population maintenance. http://purl.obolibrary.org/obo/GO_1902459 positive regulation of stem cell population maintenance http://purl.obolibrary.org/obo/GO_2000036 regulation of stem cell population maintenance Any process that activates or increases the frequency, rate or extent of stem cell population maintenance. http://purl.obolibrary.org/obo/GO_1902463 protein localization to cell leading edge http://purl.obolibrary.org/obo/GO_0008104 intracellular protein localization A process in which a protein is transported to, or maintained in, a location within a cell leading edge. http://purl.obolibrary.org/obo/GO_1902473 regulation of protein localization to synapse http://purl.obolibrary.org/obo/GO_0032880 regulation of protein localization Any process that modulates the frequency, rate or extent of protein localization to synapse. http://purl.obolibrary.org/obo/GO_1902474 positive regulation of protein localization to synapse http://purl.obolibrary.org/obo/GO_1902473 regulation of protein localization to synapse Any process that activates or increases the frequency, rate or extent of protein localization to synapse. http://purl.obolibrary.org/obo/GO_1902482 regulatory T cell apoptotic process http://purl.obolibrary.org/obo/GO_0070231 T cell apoptotic process Any apoptotic process in a regulatory T cell. http://purl.obolibrary.org/obo/GO_1902484 Sertoli cell apoptotic process http://purl.obolibrary.org/obo/GO_1904019 epithelial cell apoptotic process Any apoptotic process in a Sertoli cell. http://purl.obolibrary.org/obo/GO_1902488 cholangiocyte apoptotic process http://purl.obolibrary.org/obo/GO_1904019 epithelial cell apoptotic process Any apoptotic process in a cholangiocyte. http://purl.obolibrary.org/obo/GO_1902489 hepatoblast apoptotic process http://purl.obolibrary.org/obo/GO_0006915 apoptotic process Any apoptotic process in a hepatoblast. http://purl.obolibrary.org/obo/GO_1902490 regulation of sperm capacitation http://purl.obolibrary.org/obo/GO_2000241 regulation of reproductive process Any process that modulates the frequency, rate or extent of sperm capacitation. http://purl.obolibrary.org/obo/GO_1902491 negative regulation of sperm capacitation http://purl.obolibrary.org/obo/GO_2000242 negative regulation of reproductive process Any process that stops, prevents or reduces the frequency, rate or extent of sperm capacitation. http://purl.obolibrary.org/obo/GO_1902492 positive regulation of sperm capacitation http://purl.obolibrary.org/obo/GO_2000243 positive regulation of reproductive process Any process that activates or increases the frequency, rate or extent of sperm capacitation. http://purl.obolibrary.org/obo/GO_1902510 regulation of apoptotic DNA fragmentation http://purl.obolibrary.org/obo/GO_1903624 regulation of DNA catabolic process Any process that modulates the frequency, rate or extent of apoptotic DNA fragmentation. http://purl.obolibrary.org/obo/GO_1902511 negative regulation of apoptotic DNA fragmentation http://purl.obolibrary.org/obo/GO_1903625 negative regulation of DNA catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic DNA fragmentation. http://purl.obolibrary.org/obo/GO_1902512 positive regulation of apoptotic DNA fragmentation http://purl.obolibrary.org/obo/GO_1903626 positive regulation of DNA catabolic process Any process that activates or increases the frequency, rate or extent of apoptotic DNA fragmentation. http://purl.obolibrary.org/obo/GO_1902513 regulation of organelle transport along microtubule http://purl.obolibrary.org/obo/GO_0032386 regulation of intracellular transport Any process that modulates the frequency, rate or extent of organelle transport along microtubule. http://purl.obolibrary.org/obo/GO_1902570 protein localization to nucleolus http://purl.obolibrary.org/obo/GO_0034504 protein localization to nucleus A process in which a protein is transported to, or maintained in, a location within a nucleolus. http://purl.obolibrary.org/obo/GO_1902584 positive regulation of response to water deprivation http://purl.obolibrary.org/obo/GO_2000070 regulation of response to water deprivation Any process that activates or increases the frequency, rate or extent of response to water deprivation. http://purl.obolibrary.org/obo/GO_1902683 regulation of receptor localization to synapse http://purl.obolibrary.org/obo/GO_0032879 regulation of localization Any process that modulates the frequency, rate or extent of receptor localization to synapse. http://purl.obolibrary.org/obo/GO_1902684 negative regulation of receptor localization to synapse http://purl.obolibrary.org/obo/GO_1902683 regulation of receptor localization to synapse Any process that stops, prevents or reduces the frequency, rate or extent of receptor localization to synapse. http://purl.obolibrary.org/obo/GO_1902685 positive regulation of receptor localization to synapse http://purl.obolibrary.org/obo/GO_1902683 regulation of receptor localization to synapse Any process that activates or increases the frequency, rate or extent of receptor localization to synapse. http://purl.obolibrary.org/obo/GO_1902691 respiratory basal cell differentiation http://purl.obolibrary.org/obo/GO_0048863 stem cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a respiratory basal cell. http://purl.obolibrary.org/obo/GO_1902710 GABA receptor complex http://purl.obolibrary.org/obo/GO_0043235 receptor complex A protein complex which is capable of GABA receptor activity. Upon binding of gamma-aminobutyric acid (GABA) it transmits the signal from one side of the membrane to the other to initiate a change in cell activity. Major inhibitory receptor in vertebrate brain. Also found in other vertebrate tissues, invertebrates and possibly in plants. Effective benzodiazepine receptor. http://purl.obolibrary.org/obo/GO_1902721 negative regulation of prolactin secretion http://purl.obolibrary.org/obo/GO_0090278 negative regulation of peptide hormone secretion Any process that stops, prevents or reduces the frequency, rate or extent of prolactin secretion. http://purl.obolibrary.org/obo/GO_1902722 positive regulation of prolactin secretion http://purl.obolibrary.org/obo/GO_0090277 positive regulation of peptide hormone secretion Any process that activates or increases the frequency, rate or extent of prolactin secretion. http://purl.obolibrary.org/obo/GO_1902723 negative regulation of skeletal muscle satellite cell proliferation http://purl.obolibrary.org/obo/GO_0014859 negative regulation of skeletal muscle cell proliferation Any process that stops, prevents or reduces the frequency, rate or extent of satellite cell proliferation. http://purl.obolibrary.org/obo/GO_1902724 positive regulation of skeletal muscle satellite cell proliferation http://purl.obolibrary.org/obo/GO_0014858 positive regulation of skeletal muscle cell proliferation Any process that activates or increases the frequency, rate or extent of skeletal muscle satellite cell proliferation. http://purl.obolibrary.org/obo/GO_1902725 negative regulation of satellite cell differentiation http://purl.obolibrary.org/obo/GO_2001015 negative regulation of skeletal muscle cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of satellite cell differentiation. http://purl.obolibrary.org/obo/GO_1902726 positive regulation of skeletal muscle satellite cell differentiation http://purl.obolibrary.org/obo/GO_2001016 positive regulation of skeletal muscle cell differentiation Any process that activates or increases the frequency, rate or extent of satellite cell differentiation. http://purl.obolibrary.org/obo/GO_1902729 negative regulation of proteoglycan biosynthetic process http://purl.obolibrary.org/obo/GO_0010561 negative regulation of glycoprotein biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans. http://purl.obolibrary.org/obo/GO_1902733 regulation of growth plate cartilage chondrocyte differentiation http://purl.obolibrary.org/obo/GO_1902738 regulation of chondrocyte differentiation involved in endochondral bone morphogenesis Any process that modulates the rate, frequency, or extent of the process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the growth of a bone. A chondrocyte is a polymorphic cell that forms cartilage. http://purl.obolibrary.org/obo/GO_1902738 regulation of chondrocyte differentiation involved in endochondral bone morphogenesis http://purl.obolibrary.org/obo/GO_0032330 regulation of chondrocyte differentiation Any process that modulates the rate, frequency, or extent of the process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the development of a bone. A chondrocyte is a polymorphic cell that forms cartilage. http://purl.obolibrary.org/obo/GO_1902746 regulation of lens fiber cell differentiation http://purl.obolibrary.org/obo/GO_0030856 regulation of epithelial cell differentiation Any process that modulates the frequency, rate or extent of lens fiber cell differentiation. http://purl.obolibrary.org/obo/GO_1902747 negative regulation of lens fiber cell differentiation http://purl.obolibrary.org/obo/GO_1902746 regulation of lens fiber cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of lens fiber cell differentiation. http://purl.obolibrary.org/obo/GO_1902748 positive regulation of lens fiber cell differentiation http://purl.obolibrary.org/obo/GO_1902746 regulation of lens fiber cell differentiation Any process that activates or increases the frequency, rate or extent of lens fiber cell differentiation. http://purl.obolibrary.org/obo/GO_1902761 positive regulation of chondrocyte development http://purl.obolibrary.org/obo/GO_0061181 regulation of chondrocyte development Any process that activates or increases the frequency, rate or extent of chondrocyte development. http://purl.obolibrary.org/obo/GO_1902766 skeletal muscle satellite cell migration http://purl.obolibrary.org/obo/GO_0016477 cell migration The orderly movement of a skeletal muscle satellite cell from one site to another. Migration of these cells is a key step in the process of growth and repair of skeletal muscle cells. http://purl.obolibrary.org/obo/GO_1902809 regulation of skeletal muscle fiber differentiation http://purl.obolibrary.org/obo/GO_0010830 regulation of myotube differentiation Any process that modulates the frequency, rate or extent of skeletal muscle fiber differentiation. http://purl.obolibrary.org/obo/GO_1902810 negative regulation of skeletal muscle fiber differentiation http://purl.obolibrary.org/obo/GO_0010832 negative regulation of myotube differentiation Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle fiber differentiation. http://purl.obolibrary.org/obo/GO_1902811 positive regulation of skeletal muscle fiber differentiation http://purl.obolibrary.org/obo/GO_0010831 positive regulation of myotube differentiation Any process that activates or increases the frequency, rate or extent of skeletal muscle fiber differentiation. http://purl.obolibrary.org/obo/GO_1902816 regulation of protein localization to microtubule http://purl.obolibrary.org/obo/GO_0032880 regulation of protein localization Any process that modulates the frequency, rate or extent of protein localization to microtubule. http://purl.obolibrary.org/obo/GO_1902817 negative regulation of protein localization to microtubule http://purl.obolibrary.org/obo/GO_1903828 negative regulation of protein localization Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to microtubule. http://purl.obolibrary.org/obo/GO_1902832 negative regulation of cell proliferation in dorsal spinal cord http://purl.obolibrary.org/obo/GO_0021921 regulation of cell proliferation in dorsal spinal cord Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation in dorsal spinal cord. http://purl.obolibrary.org/obo/GO_1902833 positive regulation of cell proliferation in dorsal spinal cord http://purl.obolibrary.org/obo/GO_0021921 regulation of cell proliferation in dorsal spinal cord Any process that activates or increases the frequency, rate or extent of cell proliferation in dorsal spinal cord. http://purl.obolibrary.org/obo/GO_1902838 regulation of nuclear migration along microtubule http://purl.obolibrary.org/obo/GO_1902513 regulation of organelle transport along microtubule Any process that modulates the frequency, rate or extent of nuclear migration along microtubule. http://purl.obolibrary.org/obo/GO_1902839 negative regulation of nuclear migration along microtubule http://purl.obolibrary.org/obo/GO_1902838 regulation of nuclear migration along microtubule Any process that stops, prevents or reduces the frequency, rate or extent of nuclear migration along microtubule. http://purl.obolibrary.org/obo/GO_1902840 positive regulation of nuclear migration along microtubule http://purl.obolibrary.org/obo/GO_1902838 regulation of nuclear migration along microtubule Any process that activates or increases the frequency, rate or extent of nuclear migration along microtubule. http://purl.obolibrary.org/obo/GO_1902855 regulation of non-motile cilium assembly http://purl.obolibrary.org/obo/GO_1902017 regulation of cilium assembly Any process that modulates the frequency, rate or extent of non-motile cilium assembly. http://purl.obolibrary.org/obo/GO_1902856 negative regulation of non-motile cilium assembly http://purl.obolibrary.org/obo/GO_1902855 regulation of non-motile cilium assembly Any process that stops, prevents or reduces the frequency, rate or extent of non-motile cilium assembly. http://purl.obolibrary.org/obo/GO_1902857 positive regulation of non-motile cilium assembly http://purl.obolibrary.org/obo/GO_1902855 regulation of non-motile cilium assembly Any process that activates or increases the frequency, rate or extent of non-motile cilium assembly. http://purl.obolibrary.org/obo/GO_1902863 regulation of embryonic camera-type eye development http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of embryonic camera-type eye development. http://purl.obolibrary.org/obo/GO_1902864 negative regulation of embryonic camera-type eye development http://purl.obolibrary.org/obo/GO_1902863 regulation of embryonic camera-type eye development Any process that stops, prevents or reduces the frequency, rate or extent of embryonic camera-type eye development. http://purl.obolibrary.org/obo/GO_1902865 positive regulation of embryonic camera-type eye development http://purl.obolibrary.org/obo/GO_1902863 regulation of embryonic camera-type eye development Any process that activates or increases the frequency, rate or extent of embryonic camera-type eye development. http://purl.obolibrary.org/obo/GO_1902869 regulation of amacrine cell differentiation http://purl.obolibrary.org/obo/GO_0045664 regulation of neuron differentiation Any process that modulates the frequency, rate or extent of amacrine cell differentiation. http://purl.obolibrary.org/obo/GO_1902870 negative regulation of amacrine cell differentiation http://purl.obolibrary.org/obo/GO_0045665 negative regulation of neuron differentiation Any process that stops, prevents or reduces the frequency, rate or extent of amacrine cell differentiation. http://purl.obolibrary.org/obo/GO_1902871 positive regulation of amacrine cell differentiation http://purl.obolibrary.org/obo/GO_0045666 positive regulation of neuron differentiation Any process that activates or increases the frequency, rate or extent of amacrine cell differentiation. http://purl.obolibrary.org/obo/GO_1902908 regulation of melanosome transport http://purl.obolibrary.org/obo/GO_0051049 regulation of transport Any process that modulates the frequency, rate or extent of melanosome transport. http://purl.obolibrary.org/obo/GO_1902909 negative regulation of melanosome transport http://purl.obolibrary.org/obo/GO_0051051 negative regulation of transport Any process that stops, prevents or reduces the frequency, rate or extent of melanosome transport. http://purl.obolibrary.org/obo/GO_1902910 positive regulation of melanosome transport http://purl.obolibrary.org/obo/GO_0051050 positive regulation of transport Any process that activates or increases the frequency, rate or extent of melanosome transport. http://purl.obolibrary.org/obo/GO_1903000 regulation of lipid transport across blood-brain barrier http://purl.obolibrary.org/obo/GO_0150200 regulation of transport across blood-brain barrier Any process that modulates the frequency, rate or extent of lipid transport across blood-brain barrier. http://purl.obolibrary.org/obo/GO_1903001 negative regulation of lipid transport across blood-brain barrier http://purl.obolibrary.org/obo/GO_0150202 negative regulation of transport across blood-brain barrier Any process that stops, prevents or reduces the frequency, rate or extent of lipid transport across blood-brain barrier. http://purl.obolibrary.org/obo/GO_1903002 positive regulation of lipid transport across blood-brain barrier http://purl.obolibrary.org/obo/GO_0150201 positive regulation of transport across blood-brain barrier Any process that activates or increases the frequency, rate or extent of lipid transport across blood-brain barrier. http://purl.obolibrary.org/obo/GO_1903041 regulation of chondrocyte hypertrophy http://purl.obolibrary.org/obo/GO_0061181 regulation of chondrocyte development Any process that modulates the frequency, rate or extent of chondrocyte hypertrophy. http://purl.obolibrary.org/obo/GO_1903042 negative regulation of chondrocyte hypertrophy http://purl.obolibrary.org/obo/GO_0061182 negative regulation of chondrocyte development Any process that stops, prevents or reduces the frequency, rate or extent of chondrocyte hypertrophy. http://purl.obolibrary.org/obo/GO_1903043 positive regulation of chondrocyte hypertrophy http://purl.obolibrary.org/obo/GO_1903041 regulation of chondrocyte hypertrophy Any process that activates or increases the frequency, rate or extent of chondrocyte hypertrophy. http://purl.obolibrary.org/obo/GO_1903045 neural crest cell migration involved in sympathetic nervous system development http://purl.obolibrary.org/obo/GO_1901166 neural crest cell migration involved in autonomic nervous system development Any neural crest cell migration that is involved in sympathetic nervous system development. http://purl.obolibrary.org/obo/GO_1903056 regulation of melanosome organization http://purl.obolibrary.org/obo/GO_0033043 regulation of organelle organization Any process that modulates the frequency, rate or extent of melanosome organization. http://purl.obolibrary.org/obo/GO_1903057 negative regulation of melanosome organization http://purl.obolibrary.org/obo/GO_0010639 negative regulation of organelle organization Any process that stops, prevents or reduces the frequency, rate or extent of melanosome organization. http://purl.obolibrary.org/obo/GO_1903058 positive regulation of melanosome organization http://purl.obolibrary.org/obo/GO_0010638 positive regulation of organelle organization Any process that activates or increases the frequency, rate or extent of melanosome organization. http://purl.obolibrary.org/obo/GO_1903116 positive regulation of actin filament-based movement http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the frequency, rate or extent of actin filament-based movement. http://purl.obolibrary.org/obo/GO_1903120 protein localization to actin filament bundle http://purl.obolibrary.org/obo/GO_1903119 protein localization to actin cytoskeleton A process in which a protein is transported to, or maintained in, the location of an actin filament bundle. http://purl.obolibrary.org/obo/GO_1903179 regulation of dopamine biosynthetic process http://purl.obolibrary.org/obo/GO_0009889 regulation of biosynthetic process Any process that modulates the frequency, rate or extent of dopamine biosynthetic process. http://purl.obolibrary.org/obo/GO_1903180 negative regulation of dopamine biosynthetic process http://purl.obolibrary.org/obo/GO_0009890 negative regulation of biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of dopamine biosynthetic process. http://purl.obolibrary.org/obo/GO_1903181 positive regulation of dopamine biosynthetic process http://purl.obolibrary.org/obo/GO_0009891 positive regulation of biosynthetic process Any process that activates or increases the frequency, rate or extent of dopamine biosynthetic process. http://purl.obolibrary.org/obo/GO_1903210 podocyte apoptotic process http://purl.obolibrary.org/obo/GO_1904019 epithelial cell apoptotic process Any apoptotic process in a glomerular visceral epithelial cell. http://purl.obolibrary.org/obo/GO_1903226 positive regulation of endodermal cell differentiation http://purl.obolibrary.org/obo/GO_0045597 positive regulation of cell differentiation Any process that activates or increases the frequency, rate or extent of endodermal cell differentiation. http://purl.obolibrary.org/obo/GO_1903232 melanosome assembly http://purl.obolibrary.org/obo/GO_0032438 melanosome organization The aggregation, arrangement and bonding together of a set of components to form a melanosome, a tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored. http://purl.obolibrary.org/obo/GO_1903233 regulation of calcium ion-dependent exocytosis of neurotransmitter http://purl.obolibrary.org/obo/GO_2000300 regulation of synaptic vesicle exocytosis Any process that modulates the frequency, rate or extent of calcium ion-dependent exocytosis of neurotransmitter. http://purl.obolibrary.org/obo/GO_1903234 negative regulation of calcium ion-dependent exocytosis of neurotransmitter http://purl.obolibrary.org/obo/GO_2000301 negative regulation of synaptic vesicle exocytosis Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion-dependent exocytosis of neurotransmitter. http://purl.obolibrary.org/obo/GO_1903235 positive regulation of calcium ion-dependent exocytosis of neurotransmitter http://purl.obolibrary.org/obo/GO_2000302 positive regulation of synaptic vesicle exocytosis Any process that activates or increases the frequency, rate or extent of calcium ion-dependent exocytosis of neurotransmitter. http://purl.obolibrary.org/obo/GO_1903276 regulation of sodium ion export across plasma membrane http://purl.obolibrary.org/obo/GO_1902305 regulation of sodium ion transmembrane transport Any process that modulates the frequency, rate or extent of sodium ion export across the plasma membrane. http://purl.obolibrary.org/obo/GO_1903277 negative regulation of sodium ion export across plasma membrane http://purl.obolibrary.org/obo/GO_1903276 regulation of sodium ion export across plasma membrane Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion export across the plasma membrane. http://purl.obolibrary.org/obo/GO_1903278 positive regulation of sodium ion export across plasma membrane http://purl.obolibrary.org/obo/GO_1903276 regulation of sodium ion export across plasma membrane Any process that activates or increases the frequency, rate or extent of sodium ion export across the plasma membrane. http://purl.obolibrary.org/obo/GO_1903286 regulation of potassium ion import http://purl.obolibrary.org/obo/GO_1901379 regulation of potassium ion transmembrane transport Any process that modulates the frequency, rate or extent of potassium ion import. http://purl.obolibrary.org/obo/GO_1903287 negative regulation of potassium ion import across plasma membrane http://purl.obolibrary.org/obo/GO_1903286 regulation of potassium ion import Any process that stops, prevents or reduces the frequency, rate or extent of potassium ion import across the plasma membrane. http://purl.obolibrary.org/obo/GO_1903288 positive regulation of potassium ion import across plasma membrane http://purl.obolibrary.org/obo/GO_1903286 regulation of potassium ion import Any process that activates or increases the frequency, rate or extent of potassium ion import across the plasma membrane. http://purl.obolibrary.org/obo/GO_1903292 protein localization to Golgi membrane http://purl.obolibrary.org/obo/GO_0072657 protein localization to membrane A process in which a protein is transported to, or maintained in, a location within a Golgi membrane. http://purl.obolibrary.org/obo/GO_1903294 regulation of glutamate secretion, neurotransmission http://purl.obolibrary.org/obo/GO_0051966 regulation of synaptic transmission, glutamatergic Any process that modulates the frequency, rate or extent of glutamate secretion, neurotransmission. http://purl.obolibrary.org/obo/GO_1903295 negative regulation of glutamate secretion, neurotransmission http://purl.obolibrary.org/obo/GO_0051967 negative regulation of synaptic transmission, glutamatergic Any process that stops, prevents or reduces the frequency, rate or extent of glutamate secretion, neurotransmission. http://purl.obolibrary.org/obo/GO_1903315 negative regulation of nitrogen cycle metabolic process http://purl.obolibrary.org/obo/GO_0009892 negative regulation of metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of nitrogen cycle metabolic process. http://purl.obolibrary.org/obo/GO_1903316 positive regulation of nitrogen cycle metabolic process http://purl.obolibrary.org/obo/GO_0009893 positive regulation of metabolic process Any process that activates or increases the frequency, rate or extent of nitrogen cycle metabolic process. http://purl.obolibrary.org/obo/GO_1903326 regulation of tRNA metabolic process http://purl.obolibrary.org/obo/GO_0051252 regulation of RNA metabolic process Any process that modulates the frequency, rate or extent of tRNA metabolic process. http://purl.obolibrary.org/obo/GO_1903328 positive regulation of tRNA metabolic process http://purl.obolibrary.org/obo/GO_1903326 regulation of tRNA metabolic process Any process that activates or increases the frequency, rate or extent of tRNA metabolic process. http://purl.obolibrary.org/obo/GO_1903347 negative regulation of bicellular tight junction assembly http://purl.obolibrary.org/obo/GO_2000810 regulation of bicellular tight junction assembly Any process that stops, prevents or reduces the frequency, rate or extent of tight junction assembly. http://purl.obolibrary.org/obo/GO_1903348 positive regulation of bicellular tight junction assembly http://purl.obolibrary.org/obo/GO_2000810 regulation of bicellular tight junction assembly Any process that activates or increases the frequency, rate or extent of tight junction assembly. http://purl.obolibrary.org/obo/GO_1903350 response to dopamine http://purl.obolibrary.org/obo/GO_0071869 response to catecholamine Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dopamine stimulus. http://purl.obolibrary.org/obo/GO_1903351 cellular response to dopamine http://purl.obolibrary.org/obo/GO_0071870 cellular response to catecholamine stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dopamine stimulus. http://purl.obolibrary.org/obo/GO_1903354 regulation of distal tip cell migration http://purl.obolibrary.org/obo/GO_0030334 regulation of cell migration Any process that modulates the frequency, rate or extent of distal tip cell migration. http://purl.obolibrary.org/obo/GO_1903355 negative regulation of distal tip cell migration http://purl.obolibrary.org/obo/GO_1903354 regulation of distal tip cell migration Any process that stops, prevents or reduces the frequency, rate or extent of distal tip cell migration. http://purl.obolibrary.org/obo/GO_1903356 positive regulation of distal tip cell migration http://purl.obolibrary.org/obo/GO_1903354 regulation of distal tip cell migration Any process that activates or increases the frequency, rate or extent of distal tip cell migration. http://purl.obolibrary.org/obo/GO_1903375 facioacoustic ganglion development http://purl.obolibrary.org/obo/GO_0061550 cranial ganglion development The process whose specific outcome is the progression of an acoustico-facial VII-VIII ganglion complex over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_1903379 regulation of mitotic chromosome condensation http://purl.obolibrary.org/obo/GO_0060623 regulation of chromosome condensation Any process that modulates the frequency, rate or extent of mitotic chromosome condensation. http://purl.obolibrary.org/obo/GO_1903380 positive regulation of mitotic chromosome condensation http://purl.obolibrary.org/obo/GO_0090068 positive regulation of cell cycle process Any process that activates or increases the frequency, rate or extent of mitotic chromosome condensation. http://purl.obolibrary.org/obo/GO_1903412 response to bile acid http://purl.obolibrary.org/obo/GO_0033993 response to lipid Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bile acid stimulus. http://purl.obolibrary.org/obo/GO_1903413 cellular response to bile acid http://purl.obolibrary.org/obo/GO_1903412 response to bile acid Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bile acid stimulus. http://purl.obolibrary.org/obo/GO_1903439 calcitonin family receptor complex http://purl.obolibrary.org/obo/GO_0097648 G protein-coupled receptor complex A protein complex which is capable of calcitonin family receptor activity. Calcitonin family receptors may form dimers, trimers or tetramers; adrenomedullin and amylin receptors have only been observed as dimers so far. http://purl.obolibrary.org/obo/GO_1903444 negative regulation of brown fat cell differentiation http://purl.obolibrary.org/obo/GO_0090335 regulation of brown fat cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of brown fat cell differentiation. http://purl.obolibrary.org/obo/GO_1903487 regulation of lactation http://purl.obolibrary.org/obo/GO_2000026 regulation of multicellular organismal development Any process that modulates the frequency, rate or extent of lactation. http://purl.obolibrary.org/obo/GO_1903488 negative regulation of lactation http://purl.obolibrary.org/obo/GO_1903487 regulation of lactation Any process that stops, prevents or reduces the frequency, rate or extent of lactation. http://purl.obolibrary.org/obo/GO_1903537 meiotic cell cycle process involved in oocyte maturation http://purl.obolibrary.org/obo/GO_1903046 meiotic cell cycle process Any meiotic cell cycle process that is involved in oocyte maturation. http://purl.obolibrary.org/obo/GO_1903538 regulation of meiotic cell cycle process involved in oocyte maturation http://purl.obolibrary.org/obo/GO_2000241 regulation of reproductive process Any process that modulates the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation. http://purl.obolibrary.org/obo/GO_1903541 regulation of exosomal secretion http://purl.obolibrary.org/obo/GO_0017157 regulation of exocytosis Any process that modulates the frequency, rate or extent of exosomal secretion. http://purl.obolibrary.org/obo/GO_1903542 negative regulation of exosomal secretion http://purl.obolibrary.org/obo/GO_1903541 regulation of exosomal secretion Any process that stops, prevents or reduces the frequency, rate or extent of exosomal secretion. http://purl.obolibrary.org/obo/GO_1903543 positive regulation of exosomal secretion http://purl.obolibrary.org/obo/GO_0044089 positive regulation of cellular component biogenesis Any process that activates or increases the frequency, rate or extent of exosomal secretion. http://purl.obolibrary.org/obo/GO_1903551 regulation of extracellular exosome assembly http://purl.obolibrary.org/obo/GO_1902115 regulation of organelle assembly Any process that modulates the frequency, rate or extent of extracellular vesicular exosome assembly. http://purl.obolibrary.org/obo/GO_1903552 negative regulation of extracellular exosome assembly http://purl.obolibrary.org/obo/GO_1902116 negative regulation of organelle assembly Any process that stops, prevents or reduces the frequency, rate or extent of extracellular vesicular exosome assembly. http://purl.obolibrary.org/obo/GO_1903553 positive regulation of extracellular exosome assembly http://purl.obolibrary.org/obo/GO_1902117 positive regulation of organelle assembly Any process that activates or increases the frequency, rate or extent of extracellular vesicular exosome assembly. http://purl.obolibrary.org/obo/GO_1903564 regulation of protein localization to cilium http://purl.obolibrary.org/obo/GO_0032880 regulation of protein localization Any process that modulates the frequency, rate or extent of protein localization to cilium. http://purl.obolibrary.org/obo/GO_1903565 negative regulation of protein localization to cilium http://purl.obolibrary.org/obo/GO_1903828 negative regulation of protein localization Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cilium. http://purl.obolibrary.org/obo/GO_1903566 positive regulation of protein localization to cilium http://purl.obolibrary.org/obo/GO_1903564 regulation of protein localization to cilium Any process that activates or increases the frequency, rate or extent of protein localization to cilium. http://purl.obolibrary.org/obo/GO_1903567 regulation of protein localization to ciliary membrane http://purl.obolibrary.org/obo/GO_1904375 regulation of protein localization to cell periphery Any process that modulates the frequency, rate or extent of protein localization to ciliary membrane. http://purl.obolibrary.org/obo/GO_1903568 negative regulation of protein localization to ciliary membrane http://purl.obolibrary.org/obo/GO_1904376 negative regulation of protein localization to cell periphery Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to ciliary membrane. http://purl.obolibrary.org/obo/GO_1903569 positive regulation of protein localization to ciliary membrane http://purl.obolibrary.org/obo/GO_1904377 positive regulation of protein localization to cell periphery Any process that activates or increases the frequency, rate or extent of protein localization to ciliary membrane. http://purl.obolibrary.org/obo/GO_1903581 regulation of basophil degranulation http://purl.obolibrary.org/obo/GO_0043300 regulation of leukocyte degranulation Any process that modulates the frequency, rate or extent of basophil degranulation. http://purl.obolibrary.org/obo/GO_1903582 negative regulation of basophil degranulation http://purl.obolibrary.org/obo/GO_1903581 regulation of basophil degranulation Any process that stops, prevents or reduces the frequency, rate or extent of basophil degranulation. http://purl.obolibrary.org/obo/GO_1903583 positive regulation of basophil degranulation http://purl.obolibrary.org/obo/GO_1903581 regulation of basophil degranulation Any process that activates or increases the frequency, rate or extent of basophil degranulation. http://purl.obolibrary.org/obo/GO_1903593 regulation of histamine secretion by mast cell http://purl.obolibrary.org/obo/GO_0051239 regulation of multicellular organismal process Any process that modulates the frequency, rate or extent of histamine secretion by mast cell. http://purl.obolibrary.org/obo/GO_1903594 negative regulation of histamine secretion by mast cell http://purl.obolibrary.org/obo/GO_1903593 regulation of histamine secretion by mast cell Any process that stops, prevents or reduces the frequency, rate or extent of histamine secretion by mast cell. http://purl.obolibrary.org/obo/GO_1903595 positive regulation of histamine secretion by mast cell http://purl.obolibrary.org/obo/GO_1903593 regulation of histamine secretion by mast cell Any process that activates or increases the frequency, rate or extent of histamine secretion by mast cell. http://purl.obolibrary.org/obo/GO_1903624 regulation of DNA catabolic process http://purl.obolibrary.org/obo/GO_0009894 regulation of catabolic process Any process that modulates the frequency, rate or extent of DNA catabolic process. http://purl.obolibrary.org/obo/GO_1903625 negative regulation of DNA catabolic process http://purl.obolibrary.org/obo/GO_0009895 negative regulation of catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of DNA catabolic process. http://purl.obolibrary.org/obo/GO_1903626 positive regulation of DNA catabolic process http://purl.obolibrary.org/obo/GO_0009896 positive regulation of catabolic process Any process that activates or increases the frequency, rate or extent of DNA catabolic process. http://purl.obolibrary.org/obo/GO_1903748 negative regulation of protein localization to mitochondrion http://purl.obolibrary.org/obo/GO_1903828 negative regulation of protein localization Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to mitochondrion. http://purl.obolibrary.org/obo/GO_1903780 negative regulation of cardiac conduction http://purl.obolibrary.org/obo/GO_1903779 regulation of cardiac conduction Any process that stops, prevents or reduces the frequency, rate or extent of cardiac conduction. http://purl.obolibrary.org/obo/GO_1903781 positive regulation of cardiac conduction http://purl.obolibrary.org/obo/GO_1903779 regulation of cardiac conduction Any process that activates or increases the frequency, rate or extent of cardiac conduction. http://purl.obolibrary.org/obo/GO_1903817 negative regulation of voltage-gated potassium channel activity http://purl.obolibrary.org/obo/GO_1901017 negative regulation of potassium ion transmembrane transporter activity Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated potassium channel activity. http://purl.obolibrary.org/obo/GO_1903818 positive regulation of voltage-gated potassium channel activity http://purl.obolibrary.org/obo/GO_2001259 positive regulation of cation channel activity Any process that activates or increases the frequency, rate or extent of voltage-gated potassium channel activity. http://purl.obolibrary.org/obo/GO_1904035 regulation of epithelial cell apoptotic process http://purl.obolibrary.org/obo/GO_0042981 regulation of apoptotic process Any process that modulates the frequency, rate or extent of epithelial cell apoptotic process. http://purl.obolibrary.org/obo/GO_1904036 negative regulation of epithelial cell apoptotic process http://purl.obolibrary.org/obo/GO_1904035 regulation of epithelial cell apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell apoptotic process. http://purl.obolibrary.org/obo/GO_1904037 positive regulation of epithelial cell apoptotic process http://purl.obolibrary.org/obo/GO_0043065 positive regulation of apoptotic process Any process that activates or increases the frequency, rate or extent of epithelial cell apoptotic process. http://purl.obolibrary.org/obo/GO_1904375 regulation of protein localization to cell periphery http://purl.obolibrary.org/obo/GO_0032880 regulation of protein localization Any process that modulates the frequency, rate or extent of protein localization to cell periphery. http://purl.obolibrary.org/obo/GO_1904376 negative regulation of protein localization to cell periphery http://purl.obolibrary.org/obo/GO_1903828 negative regulation of protein localization Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell periphery. http://purl.obolibrary.org/obo/GO_1904377 positive regulation of protein localization to cell periphery http://purl.obolibrary.org/obo/GO_1904375 regulation of protein localization to cell periphery Any process that activates or increases the frequency, rate or extent of protein localization to cell periphery. http://purl.obolibrary.org/obo/GO_1904491 protein localization to ciliary transition zone http://purl.obolibrary.org/obo/GO_0061512 protein localization to cilium A process in which a protein is transported to, or maintained in, a location within a ciliary transition zone. http://purl.obolibrary.org/obo/GO_1904809 regulation of dense core granule transport http://purl.obolibrary.org/obo/GO_0032386 regulation of intracellular transport Any process that modulates the frequency, rate or extent of dense core granule transport. http://purl.obolibrary.org/obo/GO_1904810 negative regulation of dense core granule transport http://purl.obolibrary.org/obo/GO_1904809 regulation of dense core granule transport Any process that stops, prevents or reduces the frequency, rate or extent of dense core granule transport. http://purl.obolibrary.org/obo/GO_1904811 positive regulation of dense core granule transport http://purl.obolibrary.org/obo/GO_1904809 regulation of dense core granule transport Any process that activates or increases the frequency, rate or extent of dense core granule transport. http://purl.obolibrary.org/obo/GO_1905216 positive regulation of RNA binding http://purl.obolibrary.org/obo/GO_0051099 positive regulation of binding Any process that activates or increases the frequency, rate or extent of RNA binding. http://purl.obolibrary.org/obo/GO_1905483 regulation of motor neuron migration http://purl.obolibrary.org/obo/GO_2001222 regulation of neuron migration Any process that modulates the frequency, rate or extent of motor neuron migration. http://purl.obolibrary.org/obo/GO_1905484 negative regulation of motor neuron migration http://purl.obolibrary.org/obo/GO_1905483 regulation of motor neuron migration Any process that stops, prevents or reduces the frequency, rate or extent of motor neuron migration. http://purl.obolibrary.org/obo/GO_1905485 positive regulation of motor neuron migration http://purl.obolibrary.org/obo/GO_1905483 regulation of motor neuron migration Any process that activates or increases the frequency, rate or extent of motor neuron migration. http://purl.obolibrary.org/obo/GO_1905755 protein localization to cytoplasmic microtubule http://purl.obolibrary.org/obo/GO_0035372 protein localization to microtubule A process in which a protein is transported to, or maintained in, a location within a cytoplasmic microtubule. http://purl.obolibrary.org/obo/GO_1905821 positive regulation of chromosome condensation http://purl.obolibrary.org/obo/GO_0060623 regulation of chromosome condensation Any process that activates or increases the frequency, rate or extent of chromosome condensation. http://purl.obolibrary.org/obo/GO_1990010 compound eye retinal cell apoptotic process http://purl.obolibrary.org/obo/GO_1990009 retinal cell apoptotic process Any apoptotic process in a compound eye retinal cell. http://purl.obolibrary.org/obo/GO_1990048 anterograde neuronal dense core vesicle transport http://purl.obolibrary.org/obo/GO_0099519 dense core granule cytoskeletal transport The directed movement of substances in neuronal dense core vesicles along axonal microtubules towards the presynapse. http://purl.obolibrary.org/obo/GO_1990049 retrograde neuronal dense core vesicle transport http://purl.obolibrary.org/obo/GO_0099519 dense core granule cytoskeletal transport The directed movement of neuronal dense core vesicles along axonal microtubules towards the cell body. http://purl.obolibrary.org/obo/GO_1990079 cartilage homeostasis http://purl.obolibrary.org/obo/GO_0001894 tissue homeostasis A tissue homeostatic process involved in the maintenance of an internal equilibrium within cartilage, including control of cellular proliferation and death and control of metabolic function. http://purl.obolibrary.org/obo/GO_1990239 steroid hormone binding http://purl.obolibrary.org/obo/GO_0042562 hormone binding Binding to a steroid hormone. http://purl.obolibrary.org/obo/GO_1990379 lipid transport across blood-brain barrier http://purl.obolibrary.org/obo/GO_0006869 lipid transport The directed movement of lipid molecules passing through the blood-brain barrier. http://purl.obolibrary.org/obo/GO_2000036 regulation of stem cell population maintenance http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of stem cell population maintenance. http://purl.obolibrary.org/obo/GO_2000211 regulation of glutamate metabolic process http://purl.obolibrary.org/obo/GO_0006521 regulation of amino acid metabolic process Any process that modulates the frequency, rate or extent of glutamate metabolic process. http://purl.obolibrary.org/obo/GO_2000212 negative regulation of glutamate metabolic process http://purl.obolibrary.org/obo/GO_2000211 regulation of glutamate metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of glutamate metabolic process. http://purl.obolibrary.org/obo/GO_2000331 regulation of terminal button organization http://purl.obolibrary.org/obo/GO_0099174 regulation of presynapse organization Any process that modulates the frequency, rate or extent of terminal button organization. http://purl.obolibrary.org/obo/GO_2000401 regulation of lymphocyte migration http://purl.obolibrary.org/obo/GO_0071675 regulation of mononuclear cell migration Any process that modulates the frequency, rate or extent of lymphocyte migration. http://purl.obolibrary.org/obo/GO_2000402 negative regulation of lymphocyte migration http://purl.obolibrary.org/obo/GO_0071676 negative regulation of mononuclear cell migration Any process that stops, prevents or reduces the frequency, rate or extent of lymphocyte migration. http://purl.obolibrary.org/obo/GO_2000810 regulation of bicellular tight junction assembly http://purl.obolibrary.org/obo/GO_1901888 regulation of cell junction assembly Any process that modulates the frequency, rate or extent of tight junction assembly. http://purl.obolibrary.org/obo/GO_2001014 regulation of skeletal muscle cell differentiation http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the frequency, rate or extent of skeletal muscle cell differentiation. http://purl.obolibrary.org/obo/GO_2001015 negative regulation of skeletal muscle cell differentiation http://purl.obolibrary.org/obo/GO_2001014 regulation of skeletal muscle cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle cell differentiation. http://purl.obolibrary.org/obo/GO_2001016 positive regulation of skeletal muscle cell differentiation http://purl.obolibrary.org/obo/GO_0045597 positive regulation of cell differentiation Any process that activates or increases the frequency, rate or extent of skeletal muscle cell differentiation. http://purl.obolibrary.org/obo/GO_2001017 regulation of retrograde axon cargo transport http://purl.obolibrary.org/obo/GO_0032386 regulation of intracellular transport Any process that modulates the frequency, rate or extent of retrograde axon cargo transport. http://purl.obolibrary.org/obo/GO_2001018 negative regulation of retrograde axon cargo transport http://purl.obolibrary.org/obo/GO_2001017 regulation of retrograde axon cargo transport Any process that stops, prevents or reduces the frequency, rate or extent of retrograde axon cargo transport. http://purl.obolibrary.org/obo/GO_2001019 positive regulation of retrograde axon cargo transport http://purl.obolibrary.org/obo/GO_2001017 regulation of retrograde axon cargo transport Any process that activates or increases the frequency, rate or extent of retrograde axon cargo transport. http://purl.obolibrary.org/obo/GO_2001236 regulation of extrinsic apoptotic signaling pathway http://purl.obolibrary.org/obo/GO_2001233 regulation of apoptotic signaling pathway Any process that modulates the frequency, rate or extent of extrinsic apoptotic signaling pathway. http://purl.obolibrary.org/obo/GO_2001237 negative regulation of extrinsic apoptotic signaling pathway http://purl.obolibrary.org/obo/GO_2001236 regulation of extrinsic apoptotic signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of extrinsic apoptotic signaling pathway. http://purl.obolibrary.org/obo/GO_2001238 positive regulation of extrinsic apoptotic signaling pathway http://purl.obolibrary.org/obo/GO_2001236 regulation of extrinsic apoptotic signaling pathway Any process that activates or increases the frequency, rate or extent of extrinsic apoptotic signaling pathway. http://purl.obolibrary.org/obo/GO_1905632 protein localization to euchromatin http://purl.obolibrary.org/obo/GO_0071168 protein localization to chromatin A process in which a protein is transported to, or maintained in, a location within an euchromatin. http://purl.obolibrary.org/obo/GO_1905633 establishment of protein localization to euchromatin http://purl.obolibrary.org/obo/GO_0071169 establishment of protein localization to chromatin The directed movement of a protein to a specific location in an euchromatin. http://purl.obolibrary.org/obo/GO_1905664 regulation of calcium ion import across plasma membrane http://purl.obolibrary.org/obo/GO_1903169 regulation of calcium ion transmembrane transport Any process that modulates the frequency, rate or extent of calcium ion import across plasma membrane. http://purl.obolibrary.org/obo/GO_1905665 positive regulation of calcium ion import across plasma membrane http://purl.obolibrary.org/obo/GO_1905664 regulation of calcium ion import across plasma membrane Any process that activates or increases the frequency, rate or extent of calcium ion import across plasma membrane. http://purl.obolibrary.org/obo/GO_1905671 regulation of lysosome organization http://purl.obolibrary.org/obo/GO_0044088 regulation of vacuole organization Any process that modulates the frequency, rate or extent of lysosome organization. http://purl.obolibrary.org/obo/GO_1905672 negative regulation of lysosome organization http://purl.obolibrary.org/obo/GO_0010639 negative regulation of organelle organization Any process that stops, prevents or reduces the frequency, rate or extent of lysosome organization. http://purl.obolibrary.org/obo/GO_1905673 positive regulation of lysosome organization http://purl.obolibrary.org/obo/GO_1905671 regulation of lysosome organization Any process that activates or increases the frequency, rate or extent of lysosome organization. http://purl.obolibrary.org/obo/GO_1905720 cytoplasmic microtubule bundle http://purl.obolibrary.org/obo/GO_0097427 microtubule bundle Any microtubule bundle that is part of a cytoplasm. http://purl.obolibrary.org/obo/GO_1905747 negative regulation of saliva secretion http://purl.obolibrary.org/obo/GO_0060457 negative regulation of digestive system process Any process that stops, prevents or reduces the frequency, rate or extent of saliva secretion. http://purl.obolibrary.org/obo/GO_1905788 negative regulation of detection of mechanical stimulus involved in sensory perception of touch http://purl.obolibrary.org/obo/GO_0032102 negative regulation of response to external stimulus Any process that stops, prevents or reduces the frequency, rate or extent of detection of mechanical stimulus involved in sensory perception of touch. http://purl.obolibrary.org/obo/GO_1905789 positive regulation of detection of mechanical stimulus involved in sensory perception of touch http://purl.obolibrary.org/obo/GO_0031646 positive regulation of nervous system process Any process that activates or increases the frequency, rate or extent of detection of mechanical stimulus involved in sensory perception of touch. http://purl.obolibrary.org/obo/GO_1905805 excitatory synapse pruning http://purl.obolibrary.org/obo/GO_0098883 synapse pruning The disaggregation of an excitatory synapse into its constituent components. http://purl.obolibrary.org/obo/GO_1905806 regulation of synapse pruning http://purl.obolibrary.org/obo/GO_0050807 regulation of synapse organization Any process that modulates the frequency, rate or extent of synapse pruning. http://purl.obolibrary.org/obo/GO_1905807 negative regulation of synapse pruning http://purl.obolibrary.org/obo/GO_1905809 negative regulation of synapse organization Any process that stops, prevents or reduces the frequency, rate or extent of synapse pruning. http://purl.obolibrary.org/obo/GO_1905808 positive regulation of synapse pruning http://purl.obolibrary.org/obo/GO_0051130 positive regulation of cellular component organization Any process that activates or increases the frequency, rate or extent of synapse pruning. http://purl.obolibrary.org/obo/GO_1905810 regulation of excitatory synapse pruning http://purl.obolibrary.org/obo/GO_1905806 regulation of synapse pruning Any process that modulates the frequency, rate or extent of excitatory synapse pruning. http://purl.obolibrary.org/obo/GO_1905811 negative regulation of excitatory synapse pruning http://purl.obolibrary.org/obo/GO_1905810 regulation of excitatory synapse pruning Any process that stops, prevents or reduces the frequency, rate or extent of excitatory synapse pruning. http://purl.obolibrary.org/obo/GO_1905833 negative regulation of microtubule nucleation http://purl.obolibrary.org/obo/GO_0010968 regulation of microtubule nucleation Any process that stops, prevents or reduces the frequency, rate or extent of microtubule nucleation. http://purl.obolibrary.org/obo/GO_1905867 epididymis development http://purl.obolibrary.org/obo/GO_0035295 tube development The process whose specific outcome is the progression of an epididymis over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_1905871 regulation of protein localization to cell leading edge http://purl.obolibrary.org/obo/GO_0032880 regulation of protein localization Any process that modulates the frequency, rate or extent of protein localization to cell leading edge. http://purl.obolibrary.org/obo/GO_1905872 negative regulation of protein localization to cell leading edge http://purl.obolibrary.org/obo/GO_1903828 negative regulation of protein localization Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell leading edge. http://purl.obolibrary.org/obo/GO_1905873 positive regulation of protein localization to cell leading edge http://purl.obolibrary.org/obo/GO_1905871 regulation of protein localization to cell leading edge Any process that activates or increases the frequency, rate or extent of protein localization to cell leading edge. http://purl.obolibrary.org/obo/GO_1905899 regulation of smooth muscle tissue development http://purl.obolibrary.org/obo/GO_1901861 regulation of muscle tissue development Any process that modulates the frequency, rate or extent of smooth muscle tissue development. http://purl.obolibrary.org/obo/GO_1905900 negative regulation of smooth muscle tissue development http://purl.obolibrary.org/obo/GO_1905899 regulation of smooth muscle tissue development Any process that stops, prevents or reduces the frequency, rate or extent of smooth muscle tissue development. http://purl.obolibrary.org/obo/GO_1905901 positive regulation of smooth muscle tissue development http://purl.obolibrary.org/obo/GO_1905899 regulation of smooth muscle tissue development Any process that activates or increases the frequency, rate or extent of smooth muscle tissue development. http://purl.obolibrary.org/obo/GO_1905902 regulation of mesoderm formation http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of mesoderm formation. http://purl.obolibrary.org/obo/GO_1905903 negative regulation of mesoderm formation http://purl.obolibrary.org/obo/GO_1905902 regulation of mesoderm formation Any process that stops, prevents or reduces the frequency, rate or extent of mesoderm formation. http://purl.obolibrary.org/obo/GO_1905904 positive regulation of mesoderm formation http://purl.obolibrary.org/obo/GO_1905902 regulation of mesoderm formation Any process that activates or increases the frequency, rate or extent of mesoderm formation. http://purl.obolibrary.org/obo/GO_1905912 regulation of calcium ion export across plasma membrane http://purl.obolibrary.org/obo/GO_1903169 regulation of calcium ion transmembrane transport Any process that modulates the frequency, rate or extent of calcium ion export across the plasma membrane. http://purl.obolibrary.org/obo/GO_1905913 negative regulation of calcium ion export across plasma membrane http://purl.obolibrary.org/obo/GO_1905912 regulation of calcium ion export across plasma membrane Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion export across the plasma membrane. http://purl.obolibrary.org/obo/GO_1905914 positive regulation of calcium ion export across plasma membrane http://purl.obolibrary.org/obo/GO_1905912 regulation of calcium ion export across plasma membrane Any process that activates or increases the frequency, rate or extent of calcium ion export across the plasma membrane. http://purl.obolibrary.org/obo/GO_1905921 regulation of acetylcholine biosynthetic process http://purl.obolibrary.org/obo/GO_0060408 regulation of acetylcholine metabolic process Any process that modulates the frequency, rate or extent of acetylcholine biosynthetic process. http://purl.obolibrary.org/obo/GO_1905922 negative regulation of acetylcholine biosynthetic process http://purl.obolibrary.org/obo/GO_0009890 negative regulation of biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of acetylcholine biosynthetic process. http://purl.obolibrary.org/obo/GO_1905923 positive regulation of acetylcholine biosynthetic process http://purl.obolibrary.org/obo/GO_0060409 positive regulation of acetylcholine metabolic process Any process that activates or increases the frequency, rate or extent of acetylcholine biosynthetic process. http://purl.obolibrary.org/obo/GO_1905936 regulation of germ cell proliferation http://purl.obolibrary.org/obo/GO_0051239 regulation of multicellular organismal process Any process that modulates the frequency, rate or extent of germ cell proliferation. http://purl.obolibrary.org/obo/GO_1905937 negative regulation of germ cell proliferation http://purl.obolibrary.org/obo/GO_0008285 negative regulation of cell population proliferation Any process that stops, prevents or reduces the frequency, rate or extent of germ cell proliferation. http://purl.obolibrary.org/obo/GO_1905938 positive regulation of germ cell proliferation http://purl.obolibrary.org/obo/GO_1905936 regulation of germ cell proliferation Any process that activates or increases the frequency, rate or extent of germ cell proliferation. http://purl.obolibrary.org/obo/GO_1905939 regulation of gonad development http://purl.obolibrary.org/obo/GO_2000241 regulation of reproductive process Any process that modulates the frequency, rate or extent of gonad development. http://purl.obolibrary.org/obo/GO_1905940 negative regulation of gonad development http://purl.obolibrary.org/obo/GO_2000242 negative regulation of reproductive process Any process that stops, prevents or reduces the frequency, rate or extent of gonad development. http://purl.obolibrary.org/obo/GO_1905941 positive regulation of gonad development http://purl.obolibrary.org/obo/GO_2000243 positive regulation of reproductive process Any process that activates or increases the frequency, rate or extent of gonad development. http://purl.obolibrary.org/obo/GO_1905945 regulation of response to calcium ion http://purl.obolibrary.org/obo/GO_0048583 regulation of response to stimulus Any process that modulates the frequency, rate or extent of response to calcium ion. http://purl.obolibrary.org/obo/GO_1905946 negative regulation of response to calcium ion http://purl.obolibrary.org/obo/GO_1905945 regulation of response to calcium ion Any process that stops, prevents or reduces the frequency, rate or extent of response to calcium ion. http://purl.obolibrary.org/obo/GO_1905947 positive regulation of response to calcium ion http://purl.obolibrary.org/obo/GO_1905945 regulation of response to calcium ion Any process that activates or increases the frequency, rate or extent of response to calcium ion. http://purl.obolibrary.org/obo/GO_1905949 negative regulation of calcium ion import across plasma membrane http://purl.obolibrary.org/obo/GO_1905664 regulation of calcium ion import across plasma membrane Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion import across plasma membrane. http://purl.obolibrary.org/obo/GO_1990034 calcium ion export across plasma membrane http://purl.obolibrary.org/obo/GO_0140115 export across plasma membrane The directed movement of calcium ions from inside of a cell, across the plasma membrane and into the extracellular region. http://purl.obolibrary.org/obo/GO_1990086 lens fiber cell apoptotic process http://purl.obolibrary.org/obo/GO_1904019 epithelial cell apoptotic process Any apoptotic process in a lens fiber cell. Lens fiber cells are elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye. http://purl.obolibrary.org/obo/GO_1990254 keratin filament binding http://purl.obolibrary.org/obo/GO_0019215 intermediate filament binding Binding to a keratin filament, an intermediate filament composed of acidic and basic keratins (types I and II), typically expressed in epithelial cells. http://purl.obolibrary.org/obo/GO_1990280 RNA localization to chromatin http://purl.obolibrary.org/obo/GO_0006403 RNA localization A process in which RNA is transported to and maintained in a part of a chromosome that is organized into chromatin. http://purl.obolibrary.org/obo/GO_1990375 baculum development http://purl.obolibrary.org/obo/GO_0048608 reproductive structure development The reproductive developmental process whose specific outcome is the progression of the baculum over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_1990461 detoxification of iron ion http://purl.obolibrary.org/obo/GO_0061687 detoxification of inorganic compound Any process that reduces or removes the toxicity of iron ion. These include transport of iron away from sensitive areas and to compartments or complexes whose purpose is sequestration of iron ion. http://purl.obolibrary.org/obo/GO_1990497 regulation of cytoplasmic translation in response to stress http://purl.obolibrary.org/obo/GO_2000765 regulation of cytoplasmic translation Modulation of the frequency, rate or extent of cytoplasmic translation as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). http://purl.obolibrary.org/obo/GO_1990502 dense core granule maturation http://purl.obolibrary.org/obo/GO_0061792 secretory granule maturation Steps required to transform a dense core granule generated at the trans-Golgi network into a fully formed and transmissible dense core granule. Dense core granule maturation proceeds through clathrin-mediated membrane remodeling events and is essential for efficient processing of cargo within dense core granules as well as for removing factors that might otherwise interfere with dense core granule trafficking and exocytosis. http://purl.obolibrary.org/obo/GO_1990544 mitochondrial ATP transmembrane transport http://purl.obolibrary.org/obo/GO_1901679 nucleotide transmembrane transport The process in which ATP is transported across a mitochondrial membrane, into or out of the mitochondrion. http://purl.obolibrary.org/obo/GO_1990547 mitochondrial phosphate ion transmembrane transport http://purl.obolibrary.org/obo/GO_0035435 phosphate ion transmembrane transport The process in which a phosphate ion is transported across a mitochondrial membrane, into or out of the mitochondrion. http://purl.obolibrary.org/obo/GO_1990573 potassium ion import across plasma membrane http://purl.obolibrary.org/obo/GO_0098659 inorganic cation import across plasma membrane The directed movement of potassium ions from outside of a cell, across the plasma membrane and into the cytosol. http://purl.obolibrary.org/obo/GO_1990580 regulation of cytoplasmic translational termination http://purl.obolibrary.org/obo/GO_2000765 regulation of cytoplasmic translation Any process that modulates the frequency, rate or extent of cytoplasmic translational termination. http://purl.obolibrary.org/obo/GO_1990611 regulation of cytoplasmic translational initiation in response to stress http://purl.obolibrary.org/obo/GO_0043558 regulation of translational initiation in response to stress Modulation of the frequency, rate or extent of cytoplasmic translational initiation as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). http://purl.obolibrary.org/obo/GO_1990625 negative regulation of cytoplasmic translational initiation in response to stress http://purl.obolibrary.org/obo/GO_1990611 regulation of cytoplasmic translational initiation in response to stress Any process that stops, prevents or reduces the rate of cytoplasmic translation initiation as a result of a stimulus indicating the organism is under stress. http://purl.obolibrary.org/obo/GO_1990806 ligand-gated ion channel signaling pathway http://purl.obolibrary.org/obo/GO_0007165 signal transduction The series of molecular signals initiated by activation of a ligand-gated ion channel on the surface of a cell. The pathway begins with binding of an extracellular ligand to a ligand-gated ion channel and ends with a molecular function that directly regulates a downstream cellular process, e.g. transcription. http://purl.obolibrary.org/obo/GO_1990849 vacuolar localization http://purl.obolibrary.org/obo/GO_0051640 organelle localization Any process in which the vacuole is transported to, and/or maintained in, a specific location within the cell. http://purl.obolibrary.org/obo/GO_1990917 ooplasm http://purl.obolibrary.org/obo/GO_0005737 cytoplasm The cytoplasm of an ovum. http://purl.obolibrary.org/obo/GO_1990959 eosinophil homeostasis http://purl.obolibrary.org/obo/GO_0002262 myeloid cell homeostasis The process of regulating the proliferation and elimination of eosinophils such that the total number of eosinophils within a whole or part of an organism is stable over time in the absence of an outside stimulus. http://purl.obolibrary.org/obo/GO_1990960 basophil homeostasis http://purl.obolibrary.org/obo/GO_0002262 myeloid cell homeostasis The process of regulating the proliferation and elimination of basophils such that the total number of basophils within a whole or part of an organism is stable over time in the absence of an outside stimulus. http://purl.obolibrary.org/obo/GO_2000004 regulation of metanephric S-shaped body morphogenesis http://purl.obolibrary.org/obo/GO_2000027 regulation of animal organ morphogenesis Any process that modulates the frequency, rate or extent of metanephric S-shaped body morphogenesis. http://purl.obolibrary.org/obo/GO_2000005 negative regulation of metanephric S-shaped body morphogenesis http://purl.obolibrary.org/obo/GO_2000004 regulation of metanephric S-shaped body morphogenesis Any process that stops, prevents, or reduces the frequency, rate or extent of metanephric S-shaped body morphogenesis. http://purl.obolibrary.org/obo/GO_2000006 regulation of metanephric comma-shaped body morphogenesis http://purl.obolibrary.org/obo/GO_2000027 regulation of animal organ morphogenesis Any process that modulates the frequency, rate or extent of metanephric comma-shaped body morphogenesis. http://purl.obolibrary.org/obo/GO_2000007 negative regulation of metanephric comma-shaped body morphogenesis http://purl.obolibrary.org/obo/GO_2000006 regulation of metanephric comma-shaped body morphogenesis Any process that stops, prevents, or reduces the frequency, rate or extent of metanephric comma-shaped body morphogenesis. http://purl.obolibrary.org/obo/GO_2000061 regulation of ureter smooth muscle cell differentiation http://purl.obolibrary.org/obo/GO_0048634 regulation of muscle organ development Any process that modulates the frequency, rate or extent of ureter smooth muscle cell differentiation. http://purl.obolibrary.org/obo/GO_2000062 negative regulation of ureter smooth muscle cell differentiation http://purl.obolibrary.org/obo/GO_2000061 regulation of ureter smooth muscle cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of ureter smooth muscle cell differentiation. http://purl.obolibrary.org/obo/GO_2000063 positive regulation of ureter smooth muscle cell differentiation http://purl.obolibrary.org/obo/GO_2000061 regulation of ureter smooth muscle cell differentiation Any process that activates or increases the frequency, rate or extent of ureter smooth muscle cell differentiation. http://purl.obolibrary.org/obo/GO_2000074 regulation of type B pancreatic cell development http://purl.obolibrary.org/obo/GO_0060284 regulation of cell development Any process that modulates the frequency, rate or extent of pancreatic B cell development. http://purl.obolibrary.org/obo/GO_2000077 negative regulation of type B pancreatic cell development http://purl.obolibrary.org/obo/GO_0010721 negative regulation of cell development Any process that stops, prevents, or reduces the frequency, rate or extent of pancreatic B cell development. http://purl.obolibrary.org/obo/GO_2000078 positive regulation of type B pancreatic cell development http://purl.obolibrary.org/obo/GO_0010720 positive regulation of cell development Any process that activates or increases the frequency, rate or extent of pancreatic B cell development. http://purl.obolibrary.org/obo/GO_2000087 regulation of mesonephric glomerulus development http://purl.obolibrary.org/obo/GO_0090192 regulation of glomerulus development Any process that modulates the frequency, rate or extent of mesonephric glomerulus development. http://purl.obolibrary.org/obo/GO_2000088 negative regulation of mesonephric glomerulus development http://purl.obolibrary.org/obo/GO_0090194 negative regulation of glomerulus development Any process that stops, prevents, or reduces the frequency, rate or extent of mesonephric glomerulus development. http://purl.obolibrary.org/obo/GO_2000089 positive regulation of mesonephric glomerulus development http://purl.obolibrary.org/obo/GO_0090193 positive regulation of glomerulus development Any process that activates or increases the frequency, rate or extent of mesonephric glomerulus development. http://purl.obolibrary.org/obo/GO_2000093 regulation of mesonephric nephron tubule epithelial cell differentiation http://purl.obolibrary.org/obo/GO_0072182 regulation of nephron tubule epithelial cell differentiation Any process that modulates the frequency, rate or extent of mesonephric nephron tubule epithelial cell differentiation. http://purl.obolibrary.org/obo/GO_2000094 negative regulation of mesonephric nephron tubule epithelial cell differentiation http://purl.obolibrary.org/obo/GO_0072183 negative regulation of nephron tubule epithelial cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of mesonephric nephron tubule epithelial cell differentiation. http://purl.obolibrary.org/obo/GO_2000109 regulation of macrophage apoptotic process http://purl.obolibrary.org/obo/GO_2000106 regulation of leukocyte apoptotic process Any process that modulates the frequency, rate or extent of macrophage apoptotic process. http://purl.obolibrary.org/obo/GO_2000110 negative regulation of macrophage apoptotic process http://purl.obolibrary.org/obo/GO_2000109 regulation of macrophage apoptotic process Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage apoptotic process. http://purl.obolibrary.org/obo/GO_2000111 positive regulation of macrophage apoptotic process http://purl.obolibrary.org/obo/GO_2000109 regulation of macrophage apoptotic process Any process that activates or increases the frequency, rate or extent of macrophage apoptotic process. http://purl.obolibrary.org/obo/GO_2000155 positive regulation of cilium-dependent cell motility http://purl.obolibrary.org/obo/GO_1902019 regulation of cilium-dependent cell motility Any process that activates or increases the frequency, rate or extent of cilium-dependent cell motility. http://purl.obolibrary.org/obo/GO_2000173 negative regulation of branching morphogenesis of a nerve http://purl.obolibrary.org/obo/GO_0051241 negative regulation of multicellular organismal process Any process that stops, prevents, or reduces the frequency, rate or extent of branching morphogenesis of a nerve. http://purl.obolibrary.org/obo/GO_2000174 regulation of pro-T cell differentiation http://purl.obolibrary.org/obo/GO_0045580 regulation of T cell differentiation Any process that modulates the frequency, rate or extent of pro-T cell differentiation. http://purl.obolibrary.org/obo/GO_2000175 negative regulation of pro-T cell differentiation http://purl.obolibrary.org/obo/GO_2000174 regulation of pro-T cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of pro-T cell differentiation. http://purl.obolibrary.org/obo/GO_2000176 positive regulation of pro-T cell differentiation http://purl.obolibrary.org/obo/GO_2000174 regulation of pro-T cell differentiation Any process that activates or increases the frequency, rate or extent of pro-T cell differentiation. http://purl.obolibrary.org/obo/GO_2000182 regulation of progesterone biosynthetic process http://purl.obolibrary.org/obo/GO_0050810 regulation of steroid biosynthetic process Any process that modulates the frequency, rate or extent of progesterone biosynthetic process. http://purl.obolibrary.org/obo/GO_2000184 positive regulation of progesterone biosynthetic process http://purl.obolibrary.org/obo/GO_0046886 positive regulation of hormone biosynthetic process Any process that activates or increases the frequency, rate or extent of progesterone biosynthetic process. http://purl.obolibrary.org/obo/GO_2000185 regulation of phosphate transmembrane transport http://purl.obolibrary.org/obo/GO_0010966 regulation of phosphate transport Any process that modulates the frequency, rate or extent of phosphate transmembrane transport. http://purl.obolibrary.org/obo/GO_2000186 negative regulation of phosphate transmembrane transport http://purl.obolibrary.org/obo/GO_2000185 regulation of phosphate transmembrane transport Any process that stops, prevents, or reduces the frequency, rate or extent of phosphate transmembrane transport. http://purl.obolibrary.org/obo/GO_2000187 positive regulation of phosphate transmembrane transport http://purl.obolibrary.org/obo/GO_2000185 regulation of phosphate transmembrane transport Any process that activates or increases the frequency, rate or extent of phosphate transmembrane transport. http://purl.obolibrary.org/obo/GO_2000194 regulation of female gonad development http://purl.obolibrary.org/obo/GO_1905939 regulation of gonad development Any process that modulates the frequency, rate or extent of female gonad development. http://purl.obolibrary.org/obo/GO_2000195 negative regulation of female gonad development http://purl.obolibrary.org/obo/GO_2000194 regulation of female gonad development Any process that stops, prevents, or reduces the frequency, rate or extent of female gonad development. http://purl.obolibrary.org/obo/GO_2000196 positive regulation of female gonad development http://purl.obolibrary.org/obo/GO_2000194 regulation of female gonad development Any process that activates or increases the frequency, rate or extent of female gonad development. http://purl.obolibrary.org/obo/GO_2000198 negative regulation of ribonucleoprotein complex localization http://purl.obolibrary.org/obo/GO_2000197 regulation of ribonucleoprotein complex localization Any process that stops, prevents, or reduces the frequency, rate or extent of ribonucleoprotein complex localization. http://purl.obolibrary.org/obo/GO_2000199 positive regulation of ribonucleoprotein complex localization http://purl.obolibrary.org/obo/GO_2000197 regulation of ribonucleoprotein complex localization Any process that activates or increases the frequency, rate or extent of ribonucleoprotein complex localization. http://purl.obolibrary.org/obo/GO_2000224 regulation of testosterone biosynthetic process http://purl.obolibrary.org/obo/GO_0050810 regulation of steroid biosynthetic process Any process that modulates the frequency, rate or extent of testosterone biosynthetic process. http://purl.obolibrary.org/obo/GO_2000225 negative regulation of testosterone biosynthetic process http://purl.obolibrary.org/obo/GO_0010894 negative regulation of steroid biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of testosterone biosynthetic process. http://purl.obolibrary.org/obo/GO_2000226 regulation of pancreatic A cell differentiation http://purl.obolibrary.org/obo/GO_0030856 regulation of epithelial cell differentiation Any process that modulates the frequency, rate or extent of pancreatic A cell differentiation. http://purl.obolibrary.org/obo/GO_2000227 negative regulation of pancreatic A cell differentiation http://purl.obolibrary.org/obo/GO_2000226 regulation of pancreatic A cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of pancreatic A cell differentiation. http://purl.obolibrary.org/obo/GO_2000228 positive regulation of pancreatic A cell differentiation http://purl.obolibrary.org/obo/GO_2000226 regulation of pancreatic A cell differentiation Any process that activates or increases the frequency, rate or extent of pancreatic A cell differentiation. http://purl.obolibrary.org/obo/GO_2000229 regulation of pancreatic stellate cell proliferation http://purl.obolibrary.org/obo/GO_0048145 regulation of fibroblast proliferation Any process that modulates the frequency, rate or extent of pancreatic stellate cell proliferation. http://purl.obolibrary.org/obo/GO_2000230 negative regulation of pancreatic stellate cell proliferation http://purl.obolibrary.org/obo/GO_2000229 regulation of pancreatic stellate cell proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of pancreatic stellate cell proliferation. http://purl.obolibrary.org/obo/GO_2000231 positive regulation of pancreatic stellate cell proliferation http://purl.obolibrary.org/obo/GO_2000229 regulation of pancreatic stellate cell proliferation Any process that activates or increases the frequency, rate or extent of pancreatic stellate cell proliferation. http://purl.obolibrary.org/obo/GO_2000238 regulation of tRNA export from nucleus http://purl.obolibrary.org/obo/GO_2000197 regulation of ribonucleoprotein complex localization Any process that modulates the frequency, rate or extent of tRNA export from nucleus. http://purl.obolibrary.org/obo/GO_2000239 negative regulation of tRNA export from nucleus http://purl.obolibrary.org/obo/GO_2000238 regulation of tRNA export from nucleus Any process that stops, prevents, or reduces the frequency, rate or extent of tRNA export from nucleus. http://purl.obolibrary.org/obo/GO_2000240 positive regulation of tRNA export from nucleus http://purl.obolibrary.org/obo/GO_2000238 regulation of tRNA export from nucleus Any process that activates or increases the frequency, rate or extent of tRNA export from nucleus. http://purl.obolibrary.org/obo/GO_2000248 negative regulation of establishment or maintenance of neuroblast polarity http://purl.obolibrary.org/obo/GO_0010454 negative regulation of cell fate commitment Any process that stops, prevents, or reduces the frequency, rate or extent of establishment or maintenance of neuroblast polarity. http://purl.obolibrary.org/obo/GO_2000254 regulation of male germ cell proliferation http://purl.obolibrary.org/obo/GO_1905936 regulation of germ cell proliferation Any process that modulates the frequency, rate or extent of male germ cell proliferation. http://purl.obolibrary.org/obo/GO_2000255 negative regulation of male germ cell proliferation http://purl.obolibrary.org/obo/GO_2000242 negative regulation of reproductive process Any process that stops, prevents or reduces the frequency, rate or extent of male germ cell proliferation. http://purl.obolibrary.org/obo/GO_2000256 positive regulation of male germ cell proliferation http://purl.obolibrary.org/obo/GO_2000243 positive regulation of reproductive process Any process that activates or increases the frequency, rate or extent of male germ cell proliferation. http://purl.obolibrary.org/obo/GO_2000269 regulation of fibroblast apoptotic process http://purl.obolibrary.org/obo/GO_0042981 regulation of apoptotic process Any process that modulates the frequency, rate or extent of fibroblast apoptotic process. http://purl.obolibrary.org/obo/GO_2000270 negative regulation of fibroblast apoptotic process http://purl.obolibrary.org/obo/GO_2000269 regulation of fibroblast apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of fibroblast apoptotic process. http://purl.obolibrary.org/obo/GO_2000271 positive regulation of fibroblast apoptotic process http://purl.obolibrary.org/obo/GO_0043065 positive regulation of apoptotic process Any process that activates or increases the frequency, rate or extent of fibroblast apoptotic process. http://purl.obolibrary.org/obo/GO_2000287 positive regulation of myotome development http://purl.obolibrary.org/obo/GO_2000290 regulation of myotome development Any process that activates or increases the frequency, rate or extent of myotome development. http://purl.obolibrary.org/obo/GO_2000288 positive regulation of myoblast proliferation http://purl.obolibrary.org/obo/GO_2000291 regulation of myoblast proliferation Any process that activates or increases the frequency, rate or extent of myoblast proliferation. http://purl.obolibrary.org/obo/GO_2000290 regulation of myotome development http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of myotome development. http://purl.obolibrary.org/obo/GO_2000291 regulation of myoblast proliferation http://purl.obolibrary.org/obo/GO_0042127 regulation of cell population proliferation Any process that modulates the frequency, rate or extent of myoblast proliferation. http://purl.obolibrary.org/obo/GO_2000292 regulation of defecation http://purl.obolibrary.org/obo/GO_0044062 regulation of excretion Any process that modulates the frequency, rate or extent of defecation. http://purl.obolibrary.org/obo/GO_2000293 negative regulation of defecation http://purl.obolibrary.org/obo/GO_0060457 negative regulation of digestive system process Any process that stops, prevents or reduces the frequency, rate or extent of defecation. http://purl.obolibrary.org/obo/GO_2000294 positive regulation of defecation http://purl.obolibrary.org/obo/GO_2000292 regulation of defecation Any process that activates or increases the frequency, rate or extent of defecation. http://purl.obolibrary.org/obo/GO_2000316 regulation of T-helper 17 type immune response http://purl.obolibrary.org/obo/GO_0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains Any process that modulates the frequency, rate or extent of T-helper 17 type immune response. http://purl.obolibrary.org/obo/GO_2000317 negative regulation of T-helper 17 type immune response http://purl.obolibrary.org/obo/GO_2000316 regulation of T-helper 17 type immune response Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 17 type immune response. http://purl.obolibrary.org/obo/GO_2000318 positive regulation of T-helper 17 type immune response http://purl.obolibrary.org/obo/GO_2000316 regulation of T-helper 17 type immune response Any process that activates or increases the frequency, rate or extent of T-helper 17 type immune response. http://purl.obolibrary.org/obo/GO_2000319 regulation of T-helper 17 cell differentiation http://purl.obolibrary.org/obo/GO_2000316 regulation of T-helper 17 type immune response Any process that modulates the frequency, rate or extent of T-helper 17 cell differentiation. http://purl.obolibrary.org/obo/GO_2000320 negative regulation of T-helper 17 cell differentiation http://purl.obolibrary.org/obo/GO_2000319 regulation of T-helper 17 cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 17 cell differentiation. http://purl.obolibrary.org/obo/GO_2000321 positive regulation of T-helper 17 cell differentiation http://purl.obolibrary.org/obo/GO_2000319 regulation of T-helper 17 cell differentiation Any process that activates or increases the frequency, rate or extent of T-helper 17 cell differentiation. http://purl.obolibrary.org/obo/GO_2000345 regulation of hepatocyte proliferation http://purl.obolibrary.org/obo/GO_0050678 regulation of epithelial cell proliferation Any process that modulates the frequency, rate or extent of hepatocyte proliferation. http://purl.obolibrary.org/obo/GO_2000346 negative regulation of hepatocyte proliferation http://purl.obolibrary.org/obo/GO_2000345 regulation of hepatocyte proliferation Any process that stops, prevents or reduces the frequency, rate or extent of hepatocyte proliferation. http://purl.obolibrary.org/obo/GO_2000347 positive regulation of hepatocyte proliferation http://purl.obolibrary.org/obo/GO_2000345 regulation of hepatocyte proliferation Any process that activates or increases the frequency, rate or extent of hepatocyte proliferation. http://purl.obolibrary.org/obo/GO_2000351 regulation of endothelial cell apoptotic process http://purl.obolibrary.org/obo/GO_0042981 regulation of apoptotic process Any process that modulates the frequency, rate or extent of endothelial cell apoptotic process. http://purl.obolibrary.org/obo/GO_2000352 negative regulation of endothelial cell apoptotic process http://purl.obolibrary.org/obo/GO_2000351 regulation of endothelial cell apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell apoptotic process. http://purl.obolibrary.org/obo/GO_2000353 positive regulation of endothelial cell apoptotic process http://purl.obolibrary.org/obo/GO_0043065 positive regulation of apoptotic process Any process that activates or increases the frequency, rate or extent of endothelial cell apoptotic process. http://purl.obolibrary.org/obo/GO_2000354 regulation of ovarian follicle development http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of ovarian follicle development. http://purl.obolibrary.org/obo/GO_2000374 regulation of oxygen metabolic process http://purl.obolibrary.org/obo/GO_0019222 regulation of metabolic process Any process that modulates the frequency, rate or extent of oxygen metabolic process. http://purl.obolibrary.org/obo/GO_2000385 positive regulation of ectoderm development http://purl.obolibrary.org/obo/GO_2000383 regulation of ectoderm development Any process that activates or increases the frequency, rate or extent of ectoderm development. http://purl.obolibrary.org/obo/GO_2000386 positive regulation of ovarian follicle development http://purl.obolibrary.org/obo/GO_2000354 regulation of ovarian follicle development Any process that activates or increases the frequency, rate or extent of ovarian follicle development. http://purl.obolibrary.org/obo/GO_2000403 positive regulation of lymphocyte migration http://purl.obolibrary.org/obo/GO_0071677 positive regulation of mononuclear cell migration Any process that activates or increases the frequency, rate or extent of lymphocyte migration. http://purl.obolibrary.org/obo/GO_2000405 negative regulation of T cell migration http://purl.obolibrary.org/obo/GO_2000404 regulation of T cell migration Any process that stops, prevents or reduces the frequency, rate or extent of T cell migration. http://purl.obolibrary.org/obo/GO_2000410 regulation of thymocyte migration http://purl.obolibrary.org/obo/GO_2000404 regulation of T cell migration Any process that modulates the frequency, rate or extent of thymocyte migration. http://purl.obolibrary.org/obo/GO_2000411 negative regulation of thymocyte migration http://purl.obolibrary.org/obo/GO_2000410 regulation of thymocyte migration Any process that stops, prevents or reduces the frequency, rate or extent of thymocyte migration. http://purl.obolibrary.org/obo/GO_2000412 positive regulation of thymocyte migration http://purl.obolibrary.org/obo/GO_2000406 positive regulation of T cell migration Any process that activates or increases the frequency, rate or extent of thymocyte migration. http://purl.obolibrary.org/obo/GO_2000416 regulation of eosinophil migration http://purl.obolibrary.org/obo/GO_0002685 regulation of leukocyte migration Any process that modulates the frequency, rate or extent of eosinophil migration. http://purl.obolibrary.org/obo/GO_2000417 negative regulation of eosinophil migration http://purl.obolibrary.org/obo/GO_2000416 regulation of eosinophil migration Any process that stops, prevents or reduces the frequency, rate or extent of eosinophil migration. http://purl.obolibrary.org/obo/GO_2000418 positive regulation of eosinophil migration http://purl.obolibrary.org/obo/GO_2000416 regulation of eosinophil migration Any process that activates or increases the frequency, rate or extent of eosinophil migration. http://purl.obolibrary.org/obo/GO_2000422 regulation of eosinophil chemotaxis http://purl.obolibrary.org/obo/GO_0071622 regulation of granulocyte chemotaxis Any process that modulates the frequency, rate or extent of eosinophil chemotaxis. http://purl.obolibrary.org/obo/GO_2000423 negative regulation of eosinophil chemotaxis http://purl.obolibrary.org/obo/GO_0071623 negative regulation of granulocyte chemotaxis Any process that stops, prevents or reduces the frequency, rate or extent of eosinophil chemotaxis. http://purl.obolibrary.org/obo/GO_2000424 positive regulation of eosinophil chemotaxis http://purl.obolibrary.org/obo/GO_0071624 positive regulation of granulocyte chemotaxis Any process that activates or increases the frequency, rate or extent of eosinophil chemotaxis. http://purl.obolibrary.org/obo/GO_2000458 regulation of astrocyte chemotaxis http://purl.obolibrary.org/obo/GO_1903975 regulation of glial cell migration Any process that modulates the frequency, rate or extent of astrocyte chemotaxis. http://purl.obolibrary.org/obo/GO_2000459 negative regulation of astrocyte chemotaxis http://purl.obolibrary.org/obo/GO_2000458 regulation of astrocyte chemotaxis Any process that stops, prevents or reduces the frequency, rate or extent of astrocyte chemotaxis. http://purl.obolibrary.org/obo/GO_2000463 positive regulation of excitatory postsynaptic potential http://purl.obolibrary.org/obo/GO_0098815 modulation of excitatory postsynaptic potential Any process that enhances the establishment or increases the extent of the excitatory postsynaptic potential (EPSP) which is a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential. http://purl.obolibrary.org/obo/GO_2000464 positive regulation of astrocyte chemotaxis http://purl.obolibrary.org/obo/GO_2000458 regulation of astrocyte chemotaxis Any process that activates or increases the frequency, rate or extent of astrocyte chemotaxis. http://purl.obolibrary.org/obo/GO_2000471 regulation of hematopoietic stem cell migration http://purl.obolibrary.org/obo/GO_0030334 regulation of cell migration Any process that modulates the frequency, rate or extent of hematopoietic stem cell migration. http://purl.obolibrary.org/obo/GO_2000472 negative regulation of hematopoietic stem cell migration http://purl.obolibrary.org/obo/GO_2000471 regulation of hematopoietic stem cell migration Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic stem cell migration. http://purl.obolibrary.org/obo/GO_2000473 positive regulation of hematopoietic stem cell migration http://purl.obolibrary.org/obo/GO_2000471 regulation of hematopoietic stem cell migration Any process that activates or increases the frequency, rate or extent of hematopoietic stem cell migration. http://purl.obolibrary.org/obo/GO_2000477 regulation of metanephric podocyte development http://purl.obolibrary.org/obo/GO_0060284 regulation of cell development Any process that modulates the frequency, rate or extent of metanephric glomerular visceral epithelial cell development. http://purl.obolibrary.org/obo/GO_2000478 positive regulation of metanephric podocyte development http://purl.obolibrary.org/obo/GO_0010720 positive regulation of cell development Any process that activates or increases the frequency, rate or extent of metanephric glomerular visceral epithelial cell development. http://purl.obolibrary.org/obo/GO_2000489 regulation of hepatic stellate cell activation http://purl.obolibrary.org/obo/GO_0050865 regulation of cell activation Any process that modulates the frequency, rate or extent of hepatic stellate cell activation. http://purl.obolibrary.org/obo/GO_2000490 negative regulation of hepatic stellate cell activation http://purl.obolibrary.org/obo/GO_2000489 regulation of hepatic stellate cell activation Any process that stops, prevents or reduces the frequency, rate or extent of hepatic stellate cell activation. http://purl.obolibrary.org/obo/GO_2000491 positive regulation of hepatic stellate cell activation http://purl.obolibrary.org/obo/GO_2000489 regulation of hepatic stellate cell activation Any process that activates or increases the frequency, rate or extent of hepatic stellate cell activation. http://purl.obolibrary.org/obo/GO_2000495 regulation of cell proliferation involved in compound eye morphogenesis http://purl.obolibrary.org/obo/GO_0042127 regulation of cell population proliferation Any process that modulates the frequency, rate or extent of cell proliferation involved in compound eye morphogenesis. http://purl.obolibrary.org/obo/GO_2000497 positive regulation of cell proliferation involved in compound eye morphogenesis http://purl.obolibrary.org/obo/GO_2000495 regulation of cell proliferation involved in compound eye morphogenesis Any process that activates or increases the frequency, rate or extent of cell proliferation involved in compound eye morphogenesis. http://purl.obolibrary.org/obo/GO_2000501 regulation of natural killer cell chemotaxis http://purl.obolibrary.org/obo/GO_1901623 regulation of lymphocyte chemotaxis Any process that modulates the frequency, rate or extent of natural killer cell chemotaxis. http://purl.obolibrary.org/obo/GO_2000502 negative regulation of natural killer cell chemotaxis http://purl.obolibrary.org/obo/GO_2000501 regulation of natural killer cell chemotaxis Any process that stops, prevents or reduces the frequency, rate or extent of natural killer cell chemotaxis. http://purl.obolibrary.org/obo/GO_2000503 positive regulation of natural killer cell chemotaxis http://purl.obolibrary.org/obo/GO_0140131 positive regulation of lymphocyte chemotaxis Any process that activates or increases the frequency, rate or extent of natural killer cell chemotaxis. http://purl.obolibrary.org/obo/GO_2000508 regulation of dendritic cell chemotaxis http://purl.obolibrary.org/obo/GO_0071675 regulation of mononuclear cell migration Any process that modulates the frequency, rate or extent of dendritic cell chemotaxis. http://purl.obolibrary.org/obo/GO_2000509 negative regulation of dendritic cell chemotaxis http://purl.obolibrary.org/obo/GO_0071676 negative regulation of mononuclear cell migration Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell chemotaxis. http://purl.obolibrary.org/obo/GO_2000510 positive regulation of dendritic cell chemotaxis http://purl.obolibrary.org/obo/GO_0071677 positive regulation of mononuclear cell migration Any process that activates or increases the frequency, rate or extent of dendritic cell chemotaxis. http://purl.obolibrary.org/obo/GO_2000517 regulation of T-helper 1 cell activation http://purl.obolibrary.org/obo/GO_2000514 regulation of CD4-positive, alpha-beta T cell activation Any process that modulates the frequency, rate or extent of T-helper 1 cell activation. http://purl.obolibrary.org/obo/GO_2000518 negative regulation of T-helper 1 cell activation http://purl.obolibrary.org/obo/GO_2000517 regulation of T-helper 1 cell activation Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 1 cell activation. http://purl.obolibrary.org/obo/GO_2000519 positive regulation of T-helper 1 cell activation http://purl.obolibrary.org/obo/GO_2000517 regulation of T-helper 1 cell activation Any process that activates or increases the frequency, rate or extent of T-helper 1 cell activation. http://purl.obolibrary.org/obo/GO_2000527 regulation of myeloid dendritic cell chemotaxis http://purl.obolibrary.org/obo/GO_2000508 regulation of dendritic cell chemotaxis Any process that modulates the frequency, rate or extent of myeloid dendritic cell chemotaxis. http://purl.obolibrary.org/obo/GO_2000528 negative regulation of myeloid dendritic cell chemotaxis http://purl.obolibrary.org/obo/GO_2000527 regulation of myeloid dendritic cell chemotaxis Any process that stops, prevents or reduces the frequency, rate or extent of myeloid dendritic cell chemotaxis. http://purl.obolibrary.org/obo/GO_2000529 positive regulation of myeloid dendritic cell chemotaxis http://purl.obolibrary.org/obo/GO_2000527 regulation of myeloid dendritic cell chemotaxis Any process that activates or increases the frequency, rate or extent of myeloid dendritic cell chemotaxis. http://purl.obolibrary.org/obo/GO_2000537 regulation of B cell chemotaxis http://purl.obolibrary.org/obo/GO_1901623 regulation of lymphocyte chemotaxis Any process that modulates the frequency, rate or extent of B cell chemotaxis. http://purl.obolibrary.org/obo/GO_2000538 positive regulation of B cell chemotaxis http://purl.obolibrary.org/obo/GO_0140131 positive regulation of lymphocyte chemotaxis Any process that activates or increases the frequency, rate or extent of B cell chemotaxis. http://purl.obolibrary.org/obo/GO_2000547 regulation of dendritic cell dendrite assembly http://purl.obolibrary.org/obo/GO_0120032 regulation of plasma membrane bounded cell projection assembly Any process that modulates the frequency, rate or extent of dendritic cell dendrite assembly. http://purl.obolibrary.org/obo/GO_2000548 negative regulation of dendritic cell dendrite assembly http://purl.obolibrary.org/obo/GO_0120033 negative regulation of plasma membrane bounded cell projection assembly Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell dendrite assembly. http://purl.obolibrary.org/obo/GO_2000549 positive regulation of dendritic cell dendrite assembly http://purl.obolibrary.org/obo/GO_0120034 positive regulation of plasma membrane bounded cell projection assembly Any process that activates or increases the frequency, rate or extent of dendritic cell dendrite assembly. http://purl.obolibrary.org/obo/GO_2000550 negative regulation of B cell chemotaxis http://purl.obolibrary.org/obo/GO_2000537 regulation of B cell chemotaxis Any process that stops, prevents or reduces the frequency, rate or extent of B cell chemotaxis. http://purl.obolibrary.org/obo/GO_2000551 regulation of T-helper 2 cell cytokine production http://purl.obolibrary.org/obo/GO_0002828 regulation of type 2 immune response Any process that modulates the frequency, rate or extent of T-helper 2 cell cytokine production. http://purl.obolibrary.org/obo/GO_2000552 negative regulation of T-helper 2 cell cytokine production http://purl.obolibrary.org/obo/GO_2000551 regulation of T-helper 2 cell cytokine production Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 2 cell cytokine production. http://purl.obolibrary.org/obo/GO_2000553 positive regulation of T-helper 2 cell cytokine production http://purl.obolibrary.org/obo/GO_2000551 regulation of T-helper 2 cell cytokine production Any process that activates or increases the frequency, rate or extent of T-helper 2 cell cytokine production. http://purl.obolibrary.org/obo/GO_2000554 regulation of T-helper 1 cell cytokine production http://purl.obolibrary.org/obo/GO_0002825 regulation of T-helper 1 type immune response Any process that modulates the frequency, rate or extent of T-helper 1 cell cytokine production. http://purl.obolibrary.org/obo/GO_2000555 negative regulation of T-helper 1 cell cytokine production http://purl.obolibrary.org/obo/GO_2000554 regulation of T-helper 1 cell cytokine production Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 1 cell cytokine production. http://purl.obolibrary.org/obo/GO_2000556 positive regulation of T-helper 1 cell cytokine production http://purl.obolibrary.org/obo/GO_2000554 regulation of T-helper 1 cell cytokine production Any process that activates or increases the frequency, rate or extent of T-helper 1 cell cytokine production. http://purl.obolibrary.org/obo/GO_2000561 regulation of CD4-positive, alpha-beta T cell proliferation http://purl.obolibrary.org/obo/GO_2000514 regulation of CD4-positive, alpha-beta T cell activation Any process that modulates the frequency, rate or extent of CD4-positive, alpha-beta T cell proliferation. http://purl.obolibrary.org/obo/GO_2000562 negative regulation of CD4-positive, alpha-beta T cell proliferation http://purl.obolibrary.org/obo/GO_2000561 regulation of CD4-positive, alpha-beta T cell proliferation Any process that stops, prevents or reduces the frequency, rate or extent of CD4-positive, alpha-beta T cell proliferation. http://purl.obolibrary.org/obo/GO_2000563 positive regulation of CD4-positive, alpha-beta T cell proliferation http://purl.obolibrary.org/obo/GO_2000561 regulation of CD4-positive, alpha-beta T cell proliferation Any process that activates or increases the frequency, rate or extent of CD4-positive, alpha-beta T cell proliferation. http://purl.obolibrary.org/obo/GO_2000564 regulation of CD8-positive, alpha-beta T cell proliferation http://purl.obolibrary.org/obo/GO_2001185 regulation of CD8-positive, alpha-beta T cell activation Any process that modulates the frequency, rate or extent of CD8-positive, alpha-beta T cell proliferation. http://purl.obolibrary.org/obo/GO_2000565 negative regulation of CD8-positive, alpha-beta T cell proliferation http://purl.obolibrary.org/obo/GO_2000564 regulation of CD8-positive, alpha-beta T cell proliferation Any process that stops, prevents or reduces the frequency, rate or extent of CD8-positive, alpha-beta T cell proliferation. http://purl.obolibrary.org/obo/GO_2000566 positive regulation of CD8-positive, alpha-beta T cell proliferation http://purl.obolibrary.org/obo/GO_2000564 regulation of CD8-positive, alpha-beta T cell proliferation Any process that activates or increases the frequency, rate or extent of CD8-positive, alpha-beta T cell proliferation. http://purl.obolibrary.org/obo/GO_2000567 regulation of memory T cell activation http://purl.obolibrary.org/obo/GO_0050863 regulation of T cell activation Any process that modulates the frequency, rate or extent of memory T cell activation. http://purl.obolibrary.org/obo/GO_2000568 positive regulation of memory T cell activation http://purl.obolibrary.org/obo/GO_2000567 regulation of memory T cell activation Any process that activates or increases the frequency, rate or extent of memory T cell activation. http://purl.obolibrary.org/obo/GO_2000569 regulation of T-helper 2 cell activation http://purl.obolibrary.org/obo/GO_2000514 regulation of CD4-positive, alpha-beta T cell activation Any process that modulates the frequency, rate or extent of T-helper 2 cell activation. http://purl.obolibrary.org/obo/GO_2000570 positive regulation of T-helper 2 cell activation http://purl.obolibrary.org/obo/GO_2000569 regulation of T-helper 2 cell activation Any process that activates or increases the frequency, rate or extent of T-helper 2 cell activation. http://purl.obolibrary.org/obo/GO_2000595 regulation of optic nerve formation http://purl.obolibrary.org/obo/GO_0022603 regulation of anatomical structure morphogenesis Any process that modulates the frequency, rate or extent of optic nerve formation. http://purl.obolibrary.org/obo/GO_2000596 negative regulation of optic nerve formation http://purl.obolibrary.org/obo/GO_2000595 regulation of optic nerve formation Any process that stops, prevents or reduces the frequency, rate or extent of optic nerve formation. http://purl.obolibrary.org/obo/GO_2000597 positive regulation of optic nerve formation http://purl.obolibrary.org/obo/GO_2000595 regulation of optic nerve formation Any process that activates or increases the frequency, rate or extent of optic nerve formation. http://purl.obolibrary.org/obo/GO_2000609 regulation of thyroid hormone generation http://purl.obolibrary.org/obo/GO_0032350 regulation of hormone metabolic process Any process that modulates the frequency, rate or extent of thyroid hormone generation. http://purl.obolibrary.org/obo/GO_2000610 negative regulation of thyroid hormone generation http://purl.obolibrary.org/obo/GO_2000609 regulation of thyroid hormone generation Any process that stops, prevents or reduces the frequency, rate or extent of thyroid hormone generation. http://purl.obolibrary.org/obo/GO_2000611 positive regulation of thyroid hormone generation http://purl.obolibrary.org/obo/GO_2000609 regulation of thyroid hormone generation Any process that activates or increases the frequency, rate or extent of thyroid hormone generation. http://purl.obolibrary.org/obo/GO_2000612 regulation of thyroid-stimulating hormone secretion http://purl.obolibrary.org/obo/GO_0090276 regulation of peptide hormone secretion Any process that modulates the frequency, rate or extent of thyroid-stimulating hormone secretion. http://purl.obolibrary.org/obo/GO_2000613 negative regulation of thyroid-stimulating hormone secretion http://purl.obolibrary.org/obo/GO_2000612 regulation of thyroid-stimulating hormone secretion Any process that stops, prevents or reduces the frequency, rate or extent of thyroid-stimulating hormone secretion. http://purl.obolibrary.org/obo/GO_2000614 positive regulation of thyroid-stimulating hormone secretion http://purl.obolibrary.org/obo/GO_2000612 regulation of thyroid-stimulating hormone secretion Any process that activates or increases the frequency, rate or extent of thyroid-stimulating hormone secretion. http://purl.obolibrary.org/obo/GO_2000654 regulation of cellular response to testosterone stimulus http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of cellular response to testosterone stimulus. http://purl.obolibrary.org/obo/GO_2000655 negative regulation of cellular response to testosterone stimulus http://purl.obolibrary.org/obo/GO_2000654 regulation of cellular response to testosterone stimulus Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to testosterone stimulus. http://purl.obolibrary.org/obo/GO_2000668 regulation of dendritic cell apoptotic process http://purl.obolibrary.org/obo/GO_2000106 regulation of leukocyte apoptotic process Any process that modulates the frequency, rate or extent of dendritic cell apoptotic process. http://purl.obolibrary.org/obo/GO_2000669 negative regulation of dendritic cell apoptotic process http://purl.obolibrary.org/obo/GO_2000668 regulation of dendritic cell apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell apoptotic process. http://purl.obolibrary.org/obo/GO_2000670 positive regulation of dendritic cell apoptotic process http://purl.obolibrary.org/obo/GO_2000668 regulation of dendritic cell apoptotic process Any process that activates or increases the frequency, rate or extent of dendritic cell apoptotic process. http://purl.obolibrary.org/obo/GO_2000671 regulation of motor neuron apoptotic process http://purl.obolibrary.org/obo/GO_0043523 regulation of neuron apoptotic process Any process that modulates the frequency, rate or extent of motor neuron apoptotic process. http://purl.obolibrary.org/obo/GO_2000672 negative regulation of motor neuron apoptotic process http://purl.obolibrary.org/obo/GO_2000671 regulation of motor neuron apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of motor neuron apoptotic process. http://purl.obolibrary.org/obo/GO_2000673 positive regulation of motor neuron apoptotic process http://purl.obolibrary.org/obo/GO_2000671 regulation of motor neuron apoptotic process Any process that activates or increases the frequency, rate or extent of motor neuron apoptotic process. http://purl.obolibrary.org/obo/GO_2000674 regulation of type B pancreatic cell apoptotic process http://purl.obolibrary.org/obo/GO_1904035 regulation of epithelial cell apoptotic process Any process that modulates the frequency, rate or extent of type B pancreatic cell apoptotic process. http://purl.obolibrary.org/obo/GO_2000675 negative regulation of type B pancreatic cell apoptotic process http://purl.obolibrary.org/obo/GO_2000674 regulation of type B pancreatic cell apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of type B pancreatic cell apoptotic process. http://purl.obolibrary.org/obo/GO_2000676 positive regulation of type B pancreatic cell apoptotic process http://purl.obolibrary.org/obo/GO_2000674 regulation of type B pancreatic cell apoptotic process Any process that activates or increases the frequency, rate or extent of type B pancreatic cell apoptotic process. http://purl.obolibrary.org/obo/GO_2000690 regulation of cardiac muscle cell myoblast differentiation http://purl.obolibrary.org/obo/GO_0051890 regulation of cardioblast differentiation Any process that modulates the frequency, rate or extent of cardiac muscle cell myoblast differentiation. http://purl.obolibrary.org/obo/GO_2000691 negative regulation of cardiac muscle cell myoblast differentiation http://purl.obolibrary.org/obo/GO_0051892 negative regulation of cardioblast differentiation Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle cell myoblast differentiation. http://purl.obolibrary.org/obo/GO_2000700 positive regulation of cardiac muscle cell myoblast differentiation http://purl.obolibrary.org/obo/GO_2000690 regulation of cardiac muscle cell myoblast differentiation Any process that activates or increases the frequency, rate or extent of cardiac muscle cell myoblast differentiation. http://purl.obolibrary.org/obo/GO_2000729 positive regulation of mesenchymal cell proliferation involved in ureter development http://purl.obolibrary.org/obo/GO_0051094 positive regulation of developmental process Any process that activates or increases the frequency, rate or extent of mesenchymal cell proliferation involved in ureter development. http://purl.obolibrary.org/obo/GO_2000739 regulation of mesenchymal stem cell differentiation http://purl.obolibrary.org/obo/GO_2000736 regulation of stem cell differentiation Any process that modulates the frequency, rate or extent of mesenchymal stem cell differentiation. http://purl.obolibrary.org/obo/GO_2000740 negative regulation of mesenchymal stem cell differentiation http://purl.obolibrary.org/obo/GO_2000739 regulation of mesenchymal stem cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal stem cell differentiation. http://purl.obolibrary.org/obo/GO_2000741 positive regulation of mesenchymal stem cell differentiation http://purl.obolibrary.org/obo/GO_2000739 regulation of mesenchymal stem cell differentiation Any process that activates or increases the frequency, rate or extent of mesenchymal stem cell differentiation. http://purl.obolibrary.org/obo/GO_2000768 positive regulation of nephron tubule epithelial cell differentiation http://purl.obolibrary.org/obo/GO_0072182 regulation of nephron tubule epithelial cell differentiation Any process that activates or increases the frequency, rate or extent of nephron tubule epithelial cell differentiation. http://purl.obolibrary.org/obo/GO_2000791 negative regulation of mesenchymal cell proliferation involved in lung development http://purl.obolibrary.org/obo/GO_0072201 negative regulation of mesenchymal cell proliferation Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal cell proliferation involved in lung development. http://purl.obolibrary.org/obo/GO_2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis http://purl.obolibrary.org/obo/GO_2000794 regulation of epithelial cell proliferation involved in lung morphogenesis Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell proliferation involved in lung morphogenesis. http://purl.obolibrary.org/obo/GO_2000797 regulation of amniotic stem cell differentiation http://purl.obolibrary.org/obo/GO_2000739 regulation of mesenchymal stem cell differentiation Any process that modulates the frequency, rate or extent of amniotic stem cell differentiation. http://purl.obolibrary.org/obo/GO_2000798 negative regulation of amniotic stem cell differentiation http://purl.obolibrary.org/obo/GO_2000797 regulation of amniotic stem cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of amniotic stem cell differentiation. http://purl.obolibrary.org/obo/GO_2000799 positive regulation of amniotic stem cell differentiation http://purl.obolibrary.org/obo/GO_2000797 regulation of amniotic stem cell differentiation Any process that activates or increases the frequency, rate or extent of amniotic stem cell differentiation. http://purl.obolibrary.org/obo/GO_2000818 negative regulation of myoblast proliferation http://purl.obolibrary.org/obo/GO_0008285 negative regulation of cell population proliferation Any process that stops, prevents or reduces the frequency, rate or extent of myoblast proliferation. http://purl.obolibrary.org/obo/GO_2000828 regulation of parathyroid hormone secretion http://purl.obolibrary.org/obo/GO_0046883 regulation of hormone secretion Any process that modulates the frequency, rate or extent of parathyroid hormone secretion. http://purl.obolibrary.org/obo/GO_2000829 negative regulation of parathyroid hormone secretion http://purl.obolibrary.org/obo/GO_2000828 regulation of parathyroid hormone secretion Any process that stops, prevents or reduces the frequency, rate or extent of parathyroid hormone secretion. http://purl.obolibrary.org/obo/GO_2000830 positive regulation of parathyroid hormone secretion http://purl.obolibrary.org/obo/GO_2000828 regulation of parathyroid hormone secretion Any process that activates or increases the frequency, rate or extent of parathyroid hormone secretion. http://purl.obolibrary.org/obo/GO_2000834 regulation of androgen secretion http://purl.obolibrary.org/obo/GO_2000831 regulation of steroid hormone secretion Any process that modulates the frequency, rate or extent of androgen secretion. http://purl.obolibrary.org/obo/GO_2000835 negative regulation of androgen secretion http://purl.obolibrary.org/obo/GO_2000834 regulation of androgen secretion Any process that stops, prevents or reduces the frequency, rate or extent of androgen secretion. http://purl.obolibrary.org/obo/GO_2000836 positive regulation of androgen secretion http://purl.obolibrary.org/obo/GO_2000834 regulation of androgen secretion Any process that activates or increases the frequency, rate or extent of androgen secretion. http://purl.obolibrary.org/obo/GO_2000843 regulation of testosterone secretion http://purl.obolibrary.org/obo/GO_0046883 regulation of hormone secretion Any process that modulates the frequency, rate or extent of testosterone secretion. http://purl.obolibrary.org/obo/GO_2000844 negative regulation of testosterone secretion http://purl.obolibrary.org/obo/GO_2000843 regulation of testosterone secretion Any process that stops, prevents or reduces the frequency, rate or extent of testosterone secretion. http://purl.obolibrary.org/obo/GO_2000845 positive regulation of testosterone secretion http://purl.obolibrary.org/obo/GO_2000843 regulation of testosterone secretion Any process that activates or increases the frequency, rate or extent of testosterone secretion. http://purl.obolibrary.org/obo/GO_2000846 regulation of corticosteroid hormone secretion http://purl.obolibrary.org/obo/GO_2000831 regulation of steroid hormone secretion Any process that modulates the frequency, rate or extent of corticosteroid hormone secretion. http://purl.obolibrary.org/obo/GO_2000847 negative regulation of corticosteroid hormone secretion http://purl.obolibrary.org/obo/GO_2000846 regulation of corticosteroid hormone secretion Any process that stops, prevents or reduces the frequency, rate or extent of corticosteroid hormone secretion. http://purl.obolibrary.org/obo/GO_2000848 positive regulation of corticosteroid hormone secretion http://purl.obolibrary.org/obo/GO_2000846 regulation of corticosteroid hormone secretion Any process that activates or increases the frequency, rate or extent of corticosteroid hormone secretion. http://purl.obolibrary.org/obo/GO_2000855 regulation of mineralocorticoid secretion http://purl.obolibrary.org/obo/GO_2000846 regulation of corticosteroid hormone secretion Any process that modulates the frequency, rate or extent of mineralocorticoid secretion. http://purl.obolibrary.org/obo/GO_2000856 negative regulation of mineralocorticoid secretion http://purl.obolibrary.org/obo/GO_2000855 regulation of mineralocorticoid secretion Any process that stops, prevents or reduces the frequency, rate or extent of mineralocorticoid secretion. http://purl.obolibrary.org/obo/GO_2000857 positive regulation of mineralocorticoid secretion http://purl.obolibrary.org/obo/GO_2000855 regulation of mineralocorticoid secretion Any process that activates or increases the frequency, rate or extent of mineralocorticoid secretion. http://purl.obolibrary.org/obo/GO_2000859 negative regulation of aldosterone secretion http://purl.obolibrary.org/obo/GO_2000856 negative regulation of mineralocorticoid secretion Any process that stops, prevents or reduces the frequency, rate or extent of aldosterone secretion. http://purl.obolibrary.org/obo/GO_2000860 positive regulation of aldosterone secretion http://purl.obolibrary.org/obo/GO_2000857 positive regulation of mineralocorticoid secretion Any process that activates or increases the frequency, rate or extent of aldosterone secretion. http://purl.obolibrary.org/obo/GO_2000864 regulation of estradiol secretion http://purl.obolibrary.org/obo/GO_2000831 regulation of steroid hormone secretion Any process that modulates the frequency, rate or extent of estradiol secretion. http://purl.obolibrary.org/obo/GO_2000865 negative regulation of estradiol secretion http://purl.obolibrary.org/obo/GO_2000864 regulation of estradiol secretion Any process that stops, prevents or reduces the frequency, rate or extent of estradiol secretion. http://purl.obolibrary.org/obo/GO_2000866 positive regulation of estradiol secretion http://purl.obolibrary.org/obo/GO_2000864 regulation of estradiol secretion Any process that activates or increases the frequency, rate or extent of estradiol secretion. http://purl.obolibrary.org/obo/GO_2000870 regulation of progesterone secretion http://purl.obolibrary.org/obo/GO_2000194 regulation of female gonad development Any process that modulates the frequency, rate or extent of progesterone secretion. http://purl.obolibrary.org/obo/GO_2000871 negative regulation of progesterone secretion http://purl.obolibrary.org/obo/GO_2000870 regulation of progesterone secretion Any process that stops, prevents or reduces the frequency, rate or extent of progesterone secretion. http://purl.obolibrary.org/obo/GO_2000872 positive regulation of progesterone secretion http://purl.obolibrary.org/obo/GO_2000870 regulation of progesterone secretion Any process that activates or increases the frequency, rate or extent of progesterone secretion. http://purl.obolibrary.org/obo/GO_2000882 negative regulation of starch catabolic process http://purl.obolibrary.org/obo/GO_0045912 negative regulation of carbohydrate metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of starch catabolic process. http://purl.obolibrary.org/obo/GO_2000973 regulation of pro-B cell differentiation http://purl.obolibrary.org/obo/GO_1905456 regulation of lymphoid progenitor cell differentiation Any process that modulates the frequency, rate or extent of pro-B cell differentiation. http://purl.obolibrary.org/obo/GO_2000974 negative regulation of pro-B cell differentiation http://purl.obolibrary.org/obo/GO_2000973 regulation of pro-B cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of pro-B cell differentiation. http://purl.obolibrary.org/obo/GO_2000975 positive regulation of pro-B cell differentiation http://purl.obolibrary.org/obo/GO_2000973 regulation of pro-B cell differentiation Any process that activates or increases the frequency, rate or extent of pro-B cell differentiation. http://purl.obolibrary.org/obo/GO_2000977 regulation of forebrain neuron differentiation http://purl.obolibrary.org/obo/GO_0045664 regulation of neuron differentiation Any process that modulates the frequency, rate or extent of forebrain neuron differentiation. http://purl.obolibrary.org/obo/GO_2000978 negative regulation of forebrain neuron differentiation http://purl.obolibrary.org/obo/GO_0045665 negative regulation of neuron differentiation Any process that stops, prevents or reduces the frequency, rate or extent of forebrain neuron differentiation. http://purl.obolibrary.org/obo/GO_2000979 positive regulation of forebrain neuron differentiation http://purl.obolibrary.org/obo/GO_0045666 positive regulation of neuron differentiation Any process that activates or increases the frequency, rate or extent of forebrain neuron differentiation. http://purl.obolibrary.org/obo/GO_2001026 regulation of endothelial cell chemotaxis http://purl.obolibrary.org/obo/GO_0010594 regulation of endothelial cell migration Any process that modulates the frequency, rate or extent of endothelial cell chemotaxis. http://purl.obolibrary.org/obo/GO_2001027 negative regulation of endothelial cell chemotaxis http://purl.obolibrary.org/obo/GO_0010596 negative regulation of endothelial cell migration Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell chemotaxis. http://purl.obolibrary.org/obo/GO_2001035 regulation of tongue muscle cell differentiation http://purl.obolibrary.org/obo/GO_1902809 regulation of skeletal muscle fiber differentiation Any process that modulates the frequency, rate or extent of tongue muscle cell differentiation. http://purl.obolibrary.org/obo/GO_2001036 negative regulation of tongue muscle cell differentiation http://purl.obolibrary.org/obo/GO_2001035 regulation of tongue muscle cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of tongue muscle cell differentiation. http://purl.obolibrary.org/obo/GO_2001037 positive regulation of tongue muscle cell differentiation http://purl.obolibrary.org/obo/GO_2001035 regulation of tongue muscle cell differentiation Any process that activates or increases the frequency, rate or extent of tongue muscle cell differentiation. http://purl.obolibrary.org/obo/GO_2001049 regulation of tendon cell differentiation http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the frequency, rate or extent of tendon cell differentiation. http://purl.obolibrary.org/obo/GO_2001050 negative regulation of tendon cell differentiation http://purl.obolibrary.org/obo/GO_2001049 regulation of tendon cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of tendon cell differentiation. http://purl.obolibrary.org/obo/GO_2001051 positive regulation of tendon cell differentiation http://purl.obolibrary.org/obo/GO_0045597 positive regulation of cell differentiation Any process that activates or increases the frequency, rate or extent of tendon cell differentiation. http://purl.obolibrary.org/obo/GO_2001069 glycogen binding http://purl.obolibrary.org/obo/GO_0030247 polysaccharide binding Binding to glycogen. http://purl.obolibrary.org/obo/GO_2001070 starch binding http://purl.obolibrary.org/obo/GO_0030247 polysaccharide binding Binding to starch. http://purl.obolibrary.org/obo/GO_2001151 regulation of renal water transport http://purl.obolibrary.org/obo/GO_0051049 regulation of transport Any process that modulates the frequency, rate or extent of renal water transport. http://purl.obolibrary.org/obo/GO_2001152 negative regulation of renal water transport http://purl.obolibrary.org/obo/GO_0051051 negative regulation of transport Any process that stops, prevents or reduces the frequency, rate or extent of renal water transport. http://purl.obolibrary.org/obo/GO_2001153 positive regulation of renal water transport http://purl.obolibrary.org/obo/GO_0051050 positive regulation of transport Any process that activates or increases the frequency, rate or extent of renal water transport. http://purl.obolibrary.org/obo/GO_2001169 regulation of ATP biosynthetic process http://purl.obolibrary.org/obo/GO_1900371 regulation of purine nucleotide biosynthetic process Any process that modulates the frequency, rate or extent of ATP biosynthetic process. http://purl.obolibrary.org/obo/GO_2001170 negative regulation of ATP biosynthetic process http://purl.obolibrary.org/obo/GO_2001169 regulation of ATP biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of ATP biosynthetic process. http://purl.obolibrary.org/obo/GO_2001171 positive regulation of ATP biosynthetic process http://purl.obolibrary.org/obo/GO_2001169 regulation of ATP biosynthetic process Any process that activates or increases the frequency, rate or extent of ATP biosynthetic process. http://purl.obolibrary.org/obo/GO_2001198 regulation of dendritic cell differentiation http://purl.obolibrary.org/obo/GO_1902105 regulation of leukocyte differentiation Any process that modulates the frequency, rate or extent of dendritic cell differentiation. http://purl.obolibrary.org/obo/GO_2001199 negative regulation of dendritic cell differentiation http://purl.obolibrary.org/obo/GO_2001198 regulation of dendritic cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell differentiation. http://purl.obolibrary.org/obo/GO_2001200 positive regulation of dendritic cell differentiation http://purl.obolibrary.org/obo/GO_2001198 regulation of dendritic cell differentiation Any process that activates or increases the frequency, rate or extent of dendritic cell differentiation. http://purl.obolibrary.org/obo/GO_2001204 regulation of osteoclast development http://purl.obolibrary.org/obo/GO_1903706 regulation of hemopoiesis Any process that modulates the frequency, rate or extent of osteoclast development. http://purl.obolibrary.org/obo/GO_2001205 negative regulation of osteoclast development http://purl.obolibrary.org/obo/GO_2001204 regulation of osteoclast development Any process that stops, prevents or reduces the frequency, rate or extent of osteoclast development. http://purl.obolibrary.org/obo/GO_2001206 positive regulation of osteoclast development http://purl.obolibrary.org/obo/GO_2001204 regulation of osteoclast development Any process that activates or increases the frequency, rate or extent of osteoclast development. http://purl.obolibrary.org/obo/GO_2001212 regulation of vasculogenesis http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the frequency, rate or extent of vasculogenesis. http://purl.obolibrary.org/obo/GO_2001213 negative regulation of vasculogenesis http://purl.obolibrary.org/obo/GO_2001212 regulation of vasculogenesis Any process that stops, prevents or reduces the frequency, rate or extent of vasculogenesis. http://purl.obolibrary.org/obo/GO_2001214 positive regulation of vasculogenesis http://purl.obolibrary.org/obo/GO_0045597 positive regulation of cell differentiation Any process that activates or increases the frequency, rate or extent of vasculogenesis. http://purl.obolibrary.org/obo/PR_000000681 transient receptor potential cation channel TRPV http://purl.obolibrary.org/obo/PR_000044657 transient receptor potential channel protein A transient receptor potential channel protein that is a member of the subfamily V of the transient receptor potential cation channels (TRPs), with amino- and carboxyl-terminal intracellular domains separated by a domain (common with other ion channels) containing six transmembrane helices (S1-S6) in which the last two helices (S5 and S6) flank a loop, called the pore loop, which determines ion selectivity. The amino-terminal domain contains up to 6 copies of detectable ankyrin repeat (Pfam:PF00023). Most TRPs are relatively non-selective. They may be modulated by voltage changes but channel gating is generally effected by other means. http://purl.obolibrary.org/obo/PR_000001002 CD19 molecule http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CD19 gene or a 1:1 ortholog thereof. It is composed of an N-terminal extracellular domain containing two Ig-like C2-type (immunoglobulin-like) domains, followed by a single-pass transmembrane segment and a cytoplasmic C-terminal tail. CD19 expression is restricted to members of the B cell lineage. It functions as a co-receptor for B-cell antigen receptor (BCR), regulating signal transduction. http://purl.obolibrary.org/obo/PR_000001003 CD34 molecule http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CD34 gene or a 1:1 ortholog thereof. It is a leukocyte membrane protein expressed specifically by lymphohematopoietic progenitor cells. It contains a single-pass transmembrane domain and that show distinct expression on early hematopoietic precursors and vascular-associated tissue. Acts as a scaffold that presents selectin carbohydrate ligands in a clustered, tissue specific manner to allow for higher avidity interactions between leukocytes and endothelial cells during the inflammatory process. In common with related sialomucins (endoglycan and podocalyxin), the extracellular region is dominated by an N-terminal mucin-like domain, which is densely substituted with sialylated O-linked carbohydrates. The mucin-like region is followed by a cysteine-containing and presumably globular domain. This domain may fold into an immunoglobulin-like structure as the positions of 2 of the cysteines are conserved in the C2 set of the immunoglobulin superfamily. The cytoplasmic domain is around 73-76 residues long and highly conserved. http://purl.obolibrary.org/obo/PR_000001005 integrin alpha with A domain http://purl.obolibrary.org/obo/PR_000025796 integrin alpha An integrin alpha that contains an A domain. A hallmark of this class is the presence of a von Willebrand factor type A domain (Pfam:PF00092) (I-domain) of approximately 200 amino acid residues at the N terminus, which confers divalent cation binding properties. Unlike other integrin alpha proteins, they do not undergo proteolytic cleavage. http://purl.obolibrary.org/obo/PR_000001006 receptor-type tyrosine-protein phosphatase C http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human PTPRC gene or a 1:1 ortholog thereof. It is composed of an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic protein-tyrosine phosphatase domains. Contains 1 to 3 copies of the Fibronectin type III domain (Pfam:PF00041) followed by two copies of the Protein-tyrosine phosphatase (Pfam:PF00102) domain. Receptor-type tyrosine-protein phosphatase C (CD45) regulates signal transduction and lymphocyte activation by specific association with receptor molecules on T and B cells. Multiple isoforms of CD45 (180-235 kDa) can be generated asa result of alternative splicing of three variable exons 4(A), 5(B) and 6(C), encoding sequences at the N-terminal extracellular domain of the molecule. http://purl.obolibrary.org/obo/PR_000001007 integrin alpha-1 http://purl.obolibrary.org/obo/PR_000001005 integrin alpha with A domain An integrin alpha with A domain that is a translation product of the human ITGA1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001008 integrin alpha-2 http://purl.obolibrary.org/obo/PR_000001005 integrin alpha with A domain An integrin alpha with A domain that is a translation product of the human ITGA2 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001010 integrin alpha-E http://purl.obolibrary.org/obo/PR_000001005 integrin alpha with A domain An integrin alpha with A domain that is a translation product of the human ITGAE gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001012 integrin alpha-M http://purl.obolibrary.org/obo/PR_000001005 integrin alpha with A domain An integrin alpha with A domain that is a translation product of the human ITGAM gene or a 1:1 ortholog thereof. They constitute subunits of the integrin alpha-M/beta-2 receptor. This receptor is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is also a receptor for fibrinogen, factor X and ICAM1. http://purl.obolibrary.org/obo/PR_000001013 integrin alpha-X http://purl.obolibrary.org/obo/PR_000001005 integrin alpha with A domain An integrin alpha with A domain that is a translation product of the human ITGAX gene or a 1:1 ortholog thereof. Integrin alpha-X complexed with beta-2 is a receptor for fibrinogen. It recognizes the sequence GPR in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis. http://purl.obolibrary.org/obo/PR_000001014 receptor-type tyrosine-protein phosphatase C isoform CD45RABC http://purl.obolibrary.org/obo/PR_000001006 receptor-type tyrosine-protein phosphatase C A receptor-type tyrosine-protein phosphatase C that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P08575-3 or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001015 receptor-type tyrosine-protein phosphatase C isoform CD45RA http://purl.obolibrary.org/obo/PR_000050216 receptor-type tyrosine-protein phosphatase C isoform CD45R A receptor-type tyrosine-protein phosphatase C isoform CD45R that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P08575-8 or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001017 receptor-type tyrosine-protein phosphatase C isoform CD45RO http://purl.obolibrary.org/obo/PR_000001006 receptor-type tyrosine-protein phosphatase C A receptor-type tyrosine-protein phosphatase C that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P08575-4 or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001020 CD3 epsilon http://purl.obolibrary.org/obo/PR_000001018 CD3 subunit with immunoglobulin domain A CD3 subunit with immunoglobulin domain that is a translation product of the human CD3E gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001022 neural cell adhesion molecule http://purl.obolibrary.org/obo/PR_000000001 protein A protein with a domain composition consisting of a large extracellular domain, including five Ig-like C2-type domains followed by two copies of the Fibronectin type-III domain (Pfam:PF00041), a single-pass transmembrane domain and a short cytoplasmic C-terminal domain. http://purl.obolibrary.org/obo/PR_000001023 neural cell adhesion molecule NCAM http://purl.obolibrary.org/obo/PR_000001022 neural cell adhesion molecule A neural cell adhesion molecule that is involved in neuronal development, synaptic plasticity, and regeneration. http://purl.obolibrary.org/obo/PR_000001024 neural cell adhesion molecule 1 http://purl.obolibrary.org/obo/PR_000001023 neural cell adhesion molecule NCAM A neural cell adhesion molecule NCAM that is a translation product of the human NCAM1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001025 C-type lectin with multiple lectin domains http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a type I transmembrane receptor with an N-terminal cysteine-rich domain, a single Fibronectin type II (FNII) domain (Pfam:PF00040) and eight to ten copies of the Lectin C-type domain (Pfam:PF00059) (CTLDs). The presence of multiple copies of the CTLD domain is a hallmark of this class. http://purl.obolibrary.org/obo/PR_000001026 lymphocyte antigen 75 http://purl.obolibrary.org/obo/PR_000001025 C-type lectin with multiple lectin domains A C-type lectin with multiple lectin domains that is a translation product of the mouse LY75 gene or a 1:1 ortholog thereof. It consists of 12 extracellular domains (an N-terminal cysteine-rich domain, a fibronectin type II domain and 10 C-type carbohydrate recognition domains), a transmembrane region and a small cytoplasmic C terminus containing a single Tyr residue, but no obvious kinase domain. http://purl.obolibrary.org/obo/PR_000001064 transient receptor potential cation channel TRPV2 http://purl.obolibrary.org/obo/PR_000000681 transient receptor potential cation channel TRPV A transient receptor potential cation channel TRPV that is a translation product of the human TRPV2 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001065 transient receptor potential cation channel TRPV1 http://purl.obolibrary.org/obo/PR_000000681 transient receptor potential cation channel TRPV A transient receptor potential cation channel TRPV that is a translation product of the human TRPV1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001082 CD160 molecule http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CD160 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001083 CD2 molecule http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CD2 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001084 T-cell surface glycoprotein CD8 alpha chain http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CD8A gene or a 1:1 ortholog thereof. CD8 is a transmembrane that is a co-receptor for MHC class-I antigen/T-cell receptor interaction. The most common form of CD8 is composed of a CD8 alpha and a CD8 beta chain. http://purl.obolibrary.org/obo/PR_000001085 T-cell surface glycoprotein CD8 beta chain http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CD8B gene or a 1:1 ortholog thereof. CD8 is a transmembrane receptor that is a co-receptor for MHC class-I antigen/T-cell receptor interaction. The most common form of CD8 is composed of a CD8 alpha and a CD8 beta chain. http://purl.obolibrary.org/obo/PR_000001087 adhesion G-protein coupled receptor http://purl.obolibrary.org/obo/PR_000030035 G-protein coupled receptor A G-protein coupled receptor with a 7 transmembrane (secretin family) domain (Pfam:PF00002) preceded by an amino-terminal region containing one or more functional domains with adhesion-like motifs. http://purl.obolibrary.org/obo/PR_000001094 rhodopsin-like G-protein coupled receptor http://purl.obolibrary.org/obo/PR_000030035 G-protein coupled receptor A G-protein coupled receptor that contains the 7 transmembrane receptor (rhodopsin family) domain (Pfam:PF00001), which includes 7 transmembrane helices (TMI-TM7) with 3 intracellular loops (IL1-IL3) and 3 extracellular loops (EL1-EL3) between the helices. The amino-terminal region is extracellular and the carboxyl-terminal region is intracellular. Rhodopsin-like G-protein coupled receptors (GPCRs) are unique among the several classes of GPCRs in that most have a very short amino-terminal segment and several characteristic sequence motifs, particularly NSxxNPxxY in TM7 and D/E-R-Y/F between TM3 and loop IL2. Most bind their ligands within a cavity between the TM regions. http://purl.obolibrary.org/obo/PR_000001107 D(1)-like dopamine receptor http://purl.obolibrary.org/obo/PR_000044633 dopamine receptor A dopamine receptor that is a product of the DRD1 or DRD5 gene. The active form binds dopamine and its activity is mediated by G proteins that cause activation of adenylate cyclase. http://purl.obolibrary.org/obo/PR_000001108 D(2)-like dopamine receptor http://purl.obolibrary.org/obo/PR_000044633 dopamine receptor A dopamine receptor that is a product of the DRD2, DRD3, or DRD4 gene. The active form binds dopamine and its activity is mediated by G proteins that cause inhibition of adenylate cyclase. http://purl.obolibrary.org/obo/PR_000001119 animal opsin http://purl.obolibrary.org/obo/PR_000036194 eukaryotic protein A rhodopsin-like G-protein coupled receptor that is a translation product of the human OPN1LW, OPN1MW, OPN1SW, RHO, OPN3, OPN4, or OPN5 genes, 1:1 orthologs thereof, or a semi-ortholog thereof in Metazoa. The active form binds a vitamin A-based retinaldehyde chromophore through a Schiff base linkage to a Lys residue in the seventh transmembrane alpha helix. http://purl.obolibrary.org/obo/PR_000001128 chemokine receptor http://purl.obolibrary.org/obo/PR_000001094 rhodopsin-like G-protein coupled receptor A rhodopsin-like G-protein coupled receptor that in active form binds to one or more chemokines. http://purl.obolibrary.org/obo/PR_000001175 D(1A) dopamine receptor http://purl.obolibrary.org/obo/PR_000001107 D(1)-like dopamine receptor A D(1)-like dopamine receptor that is a translation product of the human DRD1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001177 D(2) dopamine receptor http://purl.obolibrary.org/obo/PR_000001108 D(2)-like dopamine receptor A D(2)-like dopamine receptor that is a translation product of the human DRD2 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001197 chemokine receptor CCR1/3/1L http://purl.obolibrary.org/obo/PR_000001128 chemokine receptor A chemokine receptor that is a translation product of the human CCR1 or CCR3 genes, the mouse CCR1L1 gene, 1:1 orthologs thereof, or a semi-ortholog thereof. http://purl.obolibrary.org/obo/PR_000001199 C-C chemokine receptor type 2 http://purl.obolibrary.org/obo/PR_000001128 chemokine receptor A chemokine receptor that is a translation product of the human CCR2 gene or a 1:1 ortholog thereof. The preferred ligands include CCL2, CCL7, CCL8, CCL13. http://purl.obolibrary.org/obo/PR_000001200 C-C chemokine receptor type 4 http://purl.obolibrary.org/obo/PR_000001128 chemokine receptor A chemokine receptor that is a translation product of the human CCR4 gene or a 1:1 ortholog thereof. The preferred ligands include CCL17 and CCL22. http://purl.obolibrary.org/obo/PR_000001201 C-C chemokine receptor type 5 http://purl.obolibrary.org/obo/PR_000001128 chemokine receptor A chemokine receptor that is a translation product of the human CCR5 gene or a 1:1 ortholog thereof. The preferred ligands include CCL3, CCL4, CCL5, CCL8, CCL14. http://purl.obolibrary.org/obo/PR_000001202 C-C chemokine receptor type 6 http://purl.obolibrary.org/obo/PR_000001128 chemokine receptor A chemokine receptor that is a translation product of the human CCR6 gene or a 1:1 ortholog thereof. The preferred ligand is CCL20. http://purl.obolibrary.org/obo/PR_000001203 C-C chemokine receptor type 7 http://purl.obolibrary.org/obo/PR_000001128 chemokine receptor A chemokine receptor that is a translation product of the human CCR7 gene or a 1:1 ortholog thereof. The preferred ligands are CCL19 and CCL21. http://purl.obolibrary.org/obo/PR_000001206 CX3C chemokine receptor 1 http://purl.obolibrary.org/obo/PR_000001128 chemokine receptor A chemokine receptor that is a translation product of the human CX3CR1 gene or a 1:1 ortholog thereof. The preferred ligand is CX3CL1. http://purl.obolibrary.org/obo/PR_000001207 C-X-C chemokine receptor type 3 http://purl.obolibrary.org/obo/PR_000001128 chemokine receptor A chemokine receptor that is a translation product of the human CXCR3 gene or a 1:1 ortholog thereof. The preferred ligands include CXCL9, CXCL10, CXCL11. http://purl.obolibrary.org/obo/PR_000001208 C-X-C chemokine receptor type 4 http://purl.obolibrary.org/obo/PR_000001128 chemokine receptor A chemokine receptor that is a translation product of the human CXCR4 gene or a 1:1 ortholog thereof. The preferred ligand is CXCL12. http://purl.obolibrary.org/obo/PR_000001209 C-X-C chemokine receptor type 5 http://purl.obolibrary.org/obo/PR_000001128 chemokine receptor A chemokine receptor that is a translation product of the human CXCR5 gene or a 1:1 ortholog thereof. The preferred ligand is CXCL13. http://purl.obolibrary.org/obo/PR_000001224 medium-wave-sensitive opsin http://purl.obolibrary.org/obo/PR_000001119 animal opsin An animal opsin that is a translation product of the human OPN1MW, OPN1MW2, or OPN1MW3 genes, 1:1 orthologs thereof, or a semi-ortholog thereof. http://purl.obolibrary.org/obo/PR_000001226 high affinity interleukin-8 receptor http://purl.obolibrary.org/obo/PR_000001128 chemokine receptor A chemokine receptor whose active form binds interleukin-8 with high affinity. http://purl.obolibrary.org/obo/PR_000001243 melanopsin http://purl.obolibrary.org/obo/PR_000001119 animal opsin An animal opsin that is a translation product of the human OPN4 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001244 long-wave-sensitive opsin 1 http://purl.obolibrary.org/obo/PR_000001119 animal opsin An animal opsin that is a translation product of the human OPN1LW gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001254 C-C chemokine receptor type 1 http://purl.obolibrary.org/obo/PR_000001197 chemokine receptor CCR1/3/1L A chemokine receptor CCR1/3/1L that is a translation product of the human CCR1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001255 C-C chemokine receptor type 3 http://purl.obolibrary.org/obo/PR_000001197 chemokine receptor CCR1/3/1L A chemokine receptor CCR1/3/1L that is a translation product of the human CCR3 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001256 C-X-C chemokine receptor type 1 http://purl.obolibrary.org/obo/PR_000001226 high affinity interleukin-8 receptor A high affinity interleukin-8 receptor that is a translation product of the human CXCR1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001257 C-X-C chemokine receptor type 2 http://purl.obolibrary.org/obo/PR_000001226 high affinity interleukin-8 receptor A high affinity interleukin-8 receptor that is a translation product of the human CXCR2 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001281 ADP-ribosyl cyclase http://purl.obolibrary.org/obo/PR_000000001 protein A protein that contains the ADP-ribosyl cyclase domain (Pfam:PF02267). http://purl.obolibrary.org/obo/PR_000001288 B-cell receptor CD22 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CD22 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001289 membrane-spanning 4-domains subfamily A member 1 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human MS4A1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001290 B7-related protein http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a member of a family that includes translation products of genes CD86, CD276, ICOSLG, and others. These are membrane-anchored proteins with a small intracellular domain and an extracellular domain with signal sequence, an Immunoglobulin V-set domain (Pfam:PF07686), and a CD80-like C2-set immunoglobulin domain (Pfam:PF08205). http://purl.obolibrary.org/obo/PR_000001292 C-type lectin domain family 4 member C http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CLEC4C gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001293 C-type lectin domain family 4 member K http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CD207 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001300 CD209 molecule http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CD209 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001307 CD44 molecule http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CD44 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001308 CD48 molecule http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CD48 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001310 CD83 molecule http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CD83 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001313 E/P-selectin http://purl.obolibrary.org/obo/PR_000000001 protein A protein with core domain structure consisting of one lectin C-type domain (Pfam:PF00059), followed by one EGF domain (Pfam:PF00008), followed by 4-9 sushi domains (Pfam:PF00084), with the P-selectins generally being longer. http://purl.obolibrary.org/obo/PR_000001318 L-selectin http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human SELL gene or a 1:1 ortholog thereof. It is a leukocyte adhesion receptor that play an important role in regulating the inflammatory response by mediating leukocyte tethering and rolling on adherent leukocytes. http://purl.obolibrary.org/obo/PR_000001319 SLAM family member 5 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CD84 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001320 alpha-(1,3)-fucosyltransferase http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a stand alone version of the Glycosyltransferase family 10 (fucosyltransferase) (Pfam:PF00852) domain. Proteins in this class may catalyze alpha-1,3 glycosidic linkages. http://purl.obolibrary.org/obo/PR_000001325 beta-1,3-glucuronyltransferase http://purl.obolibrary.org/obo/PR_000000001 protein A protein with a core domain structure consisting of a very small cytoplasmic domain followed by a transmembrane domain and a Glycosyltransferase family 43 (Pfam:PF03360) domain. http://purl.obolibrary.org/obo/PR_000001326 bone marrow stromal antigen 2 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human BST2 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001327 cadherin http://purl.obolibrary.org/obo/PR_000000001 protein A protein that has a core domain structure of signal sequence, propeptide, five Cadherin domains (Pfam:PF00028), a transmembrane region, and a Cadherin cytoplasmic region (Pfam:PF01049). Cadherins function as adhesion molecules that mediate Ca2+-dependent cell-cell adhesion in solid tissues. http://purl.obolibrary.org/obo/PR_000001332 cell adhesion molecule CEACAM8 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CEACAM8 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001337 complement receptor type 1 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CR1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001343 CD69 molecule http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CD69 gene or a 1:1 ortholog thereof. A type II transmembrane protein with a C-type lectin binding domain in the extracellular portion of the molecule. Involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets. http://purl.obolibrary.org/obo/PR_000001344 ectonucleotide pyrophosphatase/phosphodiesterase family member 3 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human ENPP3 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001345 endoglin http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human ENG gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001350 forkhead box protein P3 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human FOXP3 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001352 glycophorin http://purl.obolibrary.org/obo/PR_000000001 protein A protein that contains an extracellular Glycophorin A domain (Pfam:PF01102), followed by a single-pass transmembrane region and a small intracellular domain. A protein that is an integral protein of the red cell membrane. Proteins in this class are responsible for the molecular basis of the blood group antigens, surface markers on the outside of the red blood cell membrane. http://purl.obolibrary.org/obo/PR_000001355 immunoglobulin gamma Fc receptor II/III/IV http://purl.obolibrary.org/obo/PR_000000001 protein A protein with a core domain architecture consisting of an extracellular domain containing two copies of the Immunoglobulin domain (Pfam:PF00047), followed by a single-pass transmembrane region and a small intracellular domain. The active protein is a low affinity receptor for immunoglobulin gamma chain Fc region. Human II-a, II-b, and II-c represent a recent gene expansion and are equally related to mouse II, III, and IV. Human III-A and III-B are closely related and closer to mouse IV than to mouse III. http://purl.obolibrary.org/obo/PR_000001356 immunoglobulin gamma Fc receptor I http://purl.obolibrary.org/obo/PR_000000001 protein A protein with a core domain architecture consisting of an extracellular domain containing two or three copies of the Immunoglobulin domain (Pfam:PF00047), followed by a single-pass transmembrane region and a small intracellular domain. http://purl.obolibrary.org/obo/PR_000001380 interleukin-2 receptor subunit alpha http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human IL2RA gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001381 interleukin-2 receptor subunit beta http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human IL2RB gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001398 leukocyte immunoglobulin-like receptor subfamily A member 4 http://purl.obolibrary.org/obo/PR_000044780 leukocyte immunoglobulin-like receptor subfamily member A leukocyte immunoglobulin-like receptor subfamily member that is a translation product of the human LILRA4 gene or a 1:1 ortholog thereof. This gene is a member of a lineage-specific gene expansion in primates. http://purl.obolibrary.org/obo/PR_000001402 killer cell lectin-like receptor subfamily D member 1 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human KLRD1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001403 tetraspanin http://purl.obolibrary.org/obo/PR_000000001 protein A protein with four transmembrane domains, small intracellular amino- and carboxyl-terminal regions, and two extracellular loops, a small one (EC1) and a larger one (EC2) of about 100 residues. The EC2 loop contains at least four cysteine residues, including a highly conserved 'CCG' motif. http://purl.obolibrary.org/obo/PR_000001408 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 http://purl.obolibrary.org/obo/PR_000001281 ADP-ribosyl cyclase An ADP-ribosyl cyclase that is a translation product of the human CD38 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001412 CD86 molecule http://purl.obolibrary.org/obo/PR_000001290 B7-related protein A B7-related protein that is a translation product of the human CD86 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001431 N-formyl peptide receptor http://purl.obolibrary.org/obo/PR_000001094 rhodopsin-like G-protein coupled receptor A rhodopsin-like G-protein coupled receptor that is a translation product of the human FPR1, FPR2, or FPR3 genes, 1:1 orthologs thereof, or a semi-ortholog thereof. The active form binds N-formyl methionyl peptides. http://purl.obolibrary.org/obo/PR_000001432 P-selectin http://purl.obolibrary.org/obo/PR_000001313 E/P-selectin An E/P-selectin that is a translation product of the human SELP gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001438 CD80 molecule http://purl.obolibrary.org/obo/PR_000001290 B7-related protein A B7-related protein that is a translation product of the human CD80 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001440 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 http://purl.obolibrary.org/obo/PR_000001325 beta-1,3-glucuronyltransferase A beta-1,3-glucuronyltransferase that is a translation product of the human B3GAT1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001444 cadherin-5 http://purl.obolibrary.org/obo/PR_000001327 cadherin A cadherin that is a translation product of the human CDH5 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001447 cadherin-1 http://purl.obolibrary.org/obo/PR_000001327 cadherin A cadherin that is a translation product of the human CDH1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001456 alpha-(1,3)-fucosyltransferase 4 http://purl.obolibrary.org/obo/PR_000001320 alpha-(1,3)-fucosyltransferase An alpha-(1,3)-fucosyltransferase that is a translation product of the human FUT4 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001460 glycophorin-A http://purl.obolibrary.org/obo/PR_000001352 glycophorin A glycophorin that is a translation product of the human GYPA gene or a 1:1 ortholog thereof. It is the major sialoglycoprotein of the erythrocyte membrane. Structurally, glycophorin A consists of an N-terminal extracellular domain, heavily glycosylated on Ser and threonine residues, followed by a transmembrane region and a C-terminal cytoplasmic domain. http://purl.obolibrary.org/obo/PR_000001465 high affinity immunoglobulin gamma Fc receptor I http://purl.obolibrary.org/obo/PR_000001356 immunoglobulin gamma Fc receptor I An immunoglobulin gamma Fc receptor I that is a translation product of the human FCGR1A gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001479 low affinity immunoglobulin gamma Fc region receptor II http://purl.obolibrary.org/obo/PR_000001355 immunoglobulin gamma Fc receptor II/III/IV An immunoglobulin gamma Fc receptor II/III/IV that is a translation product of the mouse Fcgr2 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001481 low affinity immunoglobulin gamma Fc region receptor II-b http://purl.obolibrary.org/obo/PR_000001355 immunoglobulin gamma Fc receptor II/III/IV An immunoglobulin gamma Fc receptor II/III/IV that is a translation product of the human FCGR2B gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001483 low affinity immunoglobulin gamma Fc region receptor III http://purl.obolibrary.org/obo/PR_000001355 immunoglobulin gamma Fc receptor II/III/IV An immunoglobulin gamma Fc receptor II/III/IV that is a translation product of the mouse Fcgr3 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001547 prostaglandin D2 receptor DP2 http://purl.obolibrary.org/obo/PR_000001549 prostanoid receptor A prostanoid receptor that is a translation product of the human PTGDR2 gene or a 1:1 ortholog thereof. The preferred ligand is 11-dehydro-thromboxane B2. This receptor is not closely related to the prostaglandin D2 receptor encoded by PGD2. http://purl.obolibrary.org/obo/PR_000001549 prostanoid receptor http://purl.obolibrary.org/obo/PR_000001094 rhodopsin-like G-protein coupled receptor A rhodopsin-like G-protein coupled receptor that is a translation product of the human PTGDR, PTGDR2, PTGER1 to PTGER4, PTGFR, PTGIR, or TBXA2R genes, 1:1 orthologs thereof, or a semi-ortholog thereof. The active form binds prostanoids (prostaglandins and thromboxanes). http://purl.obolibrary.org/obo/PR_000001551 relaxin family peptide receptor protein http://purl.obolibrary.org/obo/PR_000001094 rhodopsin-like G-protein coupled receptor A rhodopsin-like G-protein coupled receptor that is a translation product of the human RXFP1 to RXFP4 genes, 1:1 orthologs thereof, or a semi-ortholog thereof. The active form binds relaxins. http://purl.obolibrary.org/obo/PR_000001562 vasopressin/oxytocin receptor http://purl.obolibrary.org/obo/PR_000001094 rhodopsin-like G-protein coupled receptor A rhodopsin-like G-protein coupled receptor that is a translation product of the human AVPR1A, AVPR1B, AVPR2, or OXTR genes, 1:1 orthologs thereof, or a semi-ortholog thereof. These receptors bind vasopressin or oxytocin or related nonapeptides. http://purl.obolibrary.org/obo/PR_000001580 fMet-Leu-Phe receptor http://purl.obolibrary.org/obo/PR_000001431 N-formyl peptide receptor An N-formyl peptide receptor that is a translation product of the human FPR1 gene or a 1:1 ortholog thereof. The preferred ligand is the peptide fMet-Leu-Phe, a bacterial peptide that acts as a chemoattractant in various pathophysiological conditions. http://purl.obolibrary.org/obo/PR_000001635 oxytocin receptor http://purl.obolibrary.org/obo/PR_000001562 vasopressin/oxytocin receptor A vasopressin/oxytocin receptor that is a translation product of the human OXTR gene or a 1:1 ortholog thereof. The preferred ligand is oxytocin. http://purl.obolibrary.org/obo/PR_000001666 relaxin receptor 1 http://purl.obolibrary.org/obo/PR_000001551 relaxin family peptide receptor protein A relaxin family peptide receptor protein that is a translation product of the human RXFP1 gene or a 1:1 ortholog thereof. This receptor is expressed in the brain, kidney, testis, placenta, uterus, ovary, adrenal, prostate, skin and heart. http://purl.obolibrary.org/obo/PR_000001753 transcription factor NF-kappa-B subunit http://purl.obolibrary.org/obo/PR_000000001 protein A protein that has a core domain composition consisting of a Rel homology domain (RHD) (Pfam:PF00554), an IPT/TIG domain (Pfam:PF01833), six copies of the Ankyrin repeat (Pfam:PF00023), a Death domain (Pfam:PF00531) and a C-terminal PEST region. http://purl.obolibrary.org/obo/PR_000001785 prominin http://purl.obolibrary.org/obo/PR_000000001 protein A protein with core architecture consisting of one Prominin (Pfam:PF05478) domain. The prominins are an emerging family of proteins that, among the multispan membrane proteins, display a novel topology. Mouse and human prominin and prominin-like 1 are predicted to contain five membrane spanning domains, with an N-terminal domain exposed to the extracellular space followed by four, alternating small cytoplasmic and large extracellular, loops and a cytoplasmic C-terminal domain. http://purl.obolibrary.org/obo/PR_000001786 prominin-1 http://purl.obolibrary.org/obo/PR_000001785 prominin A prominin that is a translation product of the human PROM1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001806 C-type lectin domain family 6 member A http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CLEC6A gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001807 C-type lectin domain family 7 member A http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CLEC7A gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001809 CD59-like glycoprotein http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CD59 gene, a 1:1 ortholog thereof, or pro-orthologs thereof. http://purl.obolibrary.org/obo/PR_000001810 CSF-1/PDGF receptor-type tyrosine-protein kinase http://purl.obolibrary.org/obo/PR_000000001 protein A protein with core architecture consisting of asignal sequence, 5 Ig-like domains, followed by a transmembrane sequence, followed by a Protein tyrosine kinase domain (Pfam:PF07714). However, only 1-3 of the Ig domains are detected by the Pfam HMMs in most of the sequences. Pfam:PF00047 is most common, but other members of the Ig domain clan, Pfam:PF07679 and Pfam:PF07686 can be identified instead. The fourth Ig domain lacks the disulfide-bonded cysteines. http://purl.obolibrary.org/obo/PR_000001813 adhesion G protein-coupled receptor E1 http://purl.obolibrary.org/obo/PR_000001087 adhesion G-protein coupled receptor An adhesion G-protein coupled receptor that is a translation product of the human ADGRE1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001820 MHC class II histocompatibility antigen alpha chain http://purl.obolibrary.org/obo/PR_000000001 protein A protein with core architecture consisting of a signal sequence, a Class II histocompatibility antigen, alpha domain (Pfam:PF00993) and an Immunoglobulin C1-set domain (Pfam:PF07654); these form the extracellular domain and are followed by a single-pass transmembrane region and a small cytoplasmic region. http://purl.obolibrary.org/obo/PR_000001832 SIRP/SHPS-1 family protein http://purl.obolibrary.org/obo/PR_000000001 protein A protein with core architecture consisting of a signal sequence, one Immunoglobulin V-set domain (Pfam:PF07686), two Immunoglobulin C1-set domains (Pfam:PF07654), a single-pass transmembrane region and a very small cytoplasmic region. http://purl.obolibrary.org/obo/PR_000001833 SLAM family member 1 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human SLAMF1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001835 T-box transcription factor TBX21 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human TBX21 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001836 CD7 molecule http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CD7 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001838 T-cell surface glycoprotein CD1 http://purl.obolibrary.org/obo/PR_000000001 protein A protein with core architecture consisting of a signal sequence, an extracellular region with Class I Histocompatibility antigen, domains alpha 1 and alpha two (Pfam:PF00129) and an Immunoglobulin C1-set domain (Pfam:PF07654), a single-pass transmembrane region, and a very short cytoplasmic region. Forms a heterodimer with beta-2 microglobulin. http://purl.obolibrary.org/obo/PR_000001839 T-cell surface glycoprotein CD5 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CD5 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001841 T-cell-specific surface glycoprotein CD28 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CD28 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001843 Thy-1 membrane glycoprotein http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human THY1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001844 arginase-1 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human ARG1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001850 cathepsin K http://purl.obolibrary.org/obo/PR_000040662 cathepsin-like protease A cathepsin-like protease that is a translation product of the human CTSK gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001852 cytotoxic T-lymphocyte protein 4 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CTLA4 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001854 ectonucleoside triphosphate diphosphohydrolase 1 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human ENTPD1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001858 immunoglobulin iota chain http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human VPREB1 gene or a 1:1 ortholog thereof. The gene is recently and independently duplicated in mouse and rabbit, giving rise to very closely related VPREB2 genes in those species. The protein associates with the Ig-mu chain to form a molecular complex that is expressed only on the surface of pre-B-cells. http://purl.obolibrary.org/obo/PR_000001859 immunoglobulin lambda-like polypeptide 1 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human IGLL1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001860 inducible T-cell costimulator http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human ICOS gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001861 integrin beta http://purl.obolibrary.org/obo/PR_000000001 protein A protein with core architecture consisting of a large extracellular region containing one Integrin, beta chain domain (Pfam:PF00362), up to four EGF-like domains (Pfam:PF07974), and an Integrin beta tail domain (Pfam:PF07965), followed by a single-pass transmembrane region and a small cytoplasmic region often containing an Integrin beta cytoplasmic domain (Pfam:PF08725). http://purl.obolibrary.org/obo/PR_000001865 interleukin-3 receptor class 2 alpha chain http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human IL3RA gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001867 interleukin-5 receptor subunit alpha http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human IL5RA gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001869 interleukin-7 receptor subunit alpha http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human IL7R gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001874 KLRB1-like protein http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the KLRB1 gene or its closely related paralogs (KLRB1A-F). There are lineage-specific expansions in mouse and rat. http://purl.obolibrary.org/obo/PR_000001879 leukosialin http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human SPN gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001880 low affinity immunoglobulin epsilon Fc receptor http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human FCER2 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001883 lysosome-associated membrane protein http://purl.obolibrary.org/obo/PR_000000001 protein A protein with core architecture consisting of a Lysosome-associated membrane glycoprotein (Pfam:PF01299) domain. It is a single-pass type I membrane protein that shuttles between lysosomes, endosomes, and the plasma membrane. http://purl.obolibrary.org/obo/PR_000001884 macrophage receptor MARCO http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human MARCO gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001885 macrophage scavenger receptor types I and II http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human MSR1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001888 membrane alanyl aminopeptidase-like metallopeptidase http://purl.obolibrary.org/obo/PR_000000001 protein A protein with core architecture consisting of a Peptidase family M1 domain (Pfam:PF01433). http://purl.obolibrary.org/obo/PR_000001889 CD14 molecule http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CD14 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001892 CD33 molecule http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CD33 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001893 natural cytotoxicity triggering receptor 1 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human NCR1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001894 natural cytotoxicity triggering receptor 2 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human NCR2 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001896 natural killer cell receptor 2B4 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CD244 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001897 natural killer cell receptor NKG2 http://purl.obolibrary.org/obo/PR_000000001 protein A protein with core architecture consisting of an as yet unnamed domain in the amino-terminal half and a carboxyl-terminal Lectin C-type domain (Pfam:PF00059). http://purl.obolibrary.org/obo/PR_000001898 neprilysin http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human MME gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001902 nuclear receptor ROR-gamma http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human RORC gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001903 paired box protein PAX-5 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human PAX5 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001905 platelet glycoprotein 4 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CD36 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001907 platelet glycoprotein Ib alpha chain http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human GP1BA gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001919 programmed cell death protein 1 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human PDCD1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001925 scavenger receptor cysteine-rich type 1 protein M130 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CD163 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001927 sialic acid-binding Ig-like lectin 5 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human SIGLEC5 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001928 sialic acid-binding Ig-like lectin 6 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human SIGLEC6 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001931 sialoadhesin http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human SIGLEC1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001932 signal transducer CD24 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CD24 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001935 syndecan-1 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human SDC1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001937 tartrate-resistant acid phosphatase type 5 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human ACP5 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001938 thrombomodulin-like receptor http://purl.obolibrary.org/obo/PR_000000001 protein A protein with core architecture consisting of a signal sequence, a Lectin C-type domain (Pfam:PF00059), 5 or 6 EGF-like domains (Pfam:PF00008, Pfam:PF09064, or Pfam:PF07645), a transmembrane region, and a small cytoplasmic region (36-51 amino acids). http://purl.obolibrary.org/obo/PR_000001941 trans-acting T-cell-specific transcription factor GATA-3 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human GATA3 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001944 transcription factor PU.1 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human SPI1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001945 transferrin receptor protein 1 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human TFRC gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001950 tumor necrosis factor ligand superfamily member 5 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CD40LG gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001954 tumor necrosis factor receptor superfamily member 11A http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human TNFRSF11A gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001963 CD27 molecule http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CD27 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001968 tyrosine-protein phosphatase non-receptor type substrate 1 http://purl.obolibrary.org/obo/PR_000001832 SIRP/SHPS-1 family protein A SIRP/SHPS-1 family protein that is a translation product of the human SIRPA gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001969 urokinase plasminogen activator surface receptor http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human PLAUR gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001975 voltage-gated sodium channel subunit alpha http://purl.obolibrary.org/obo/PR_000044660 voltage-gated sodium channel protein A voltage-gated sodium channel protein that has a core architecture consisting of four similar domains (I-VI), each containing six transmembrane helices (S1-S6), with a pore loop between S5 and S6. The S4 segments contain positively charged amino acids at every third position and serve as voltage sensors. These large proteins (about 2000 amino acids) contain a unique Sodium ion transport-associated domain (Pfam:PF06512) located between two pairs of Ion transport protein domains (Pfam:PF00520). An IQ calmodulin-binding motif (Pfam:PF00612) may be found about 100 amino acids from the carboxyl end. http://purl.obolibrary.org/obo/PR_000001998 C-C motif chemokine 3/4 http://purl.obolibrary.org/obo/PR_000001808 C/C-C motif small inducible chemokine A C/C-C motif small inducible chemokine that is a translation product of the CCL3, CCL3L1/CCL3L3, or CCL4 gene. http://purl.obolibrary.org/obo/PR_000002001 receptor-type tyrosine-protein kinase FLT3 http://purl.obolibrary.org/obo/PR_000001810 CSF-1/PDGF receptor-type tyrosine-protein kinase A CSF-1/PDGF receptor-type tyrosine-protein kinase that is a translation product of the human FLT3 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000002015 MHC class II histocompatibility antigen alpha chain DRA http://purl.obolibrary.org/obo/PR_000001820 MHC class II histocompatibility antigen alpha chain An MHC class II histocompatibility antigen alpha chain that is a translation product of the human HLA-DRA gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000002023 NKG2-A/NKG2-B type II integral membrane protein http://purl.obolibrary.org/obo/PR_000001897 natural killer cell receptor NKG2 A natural killer cell receptor NKG2 that is a translation product of the human KLRC1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000002025 T-cell surface glycoprotein CD1a http://purl.obolibrary.org/obo/PR_000001838 T-cell surface glycoprotein CD1 A T-cell surface glycoprotein CD1 that is a translation product of the human CD1A gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000002027 T-cell surface glycoprotein CD1c http://purl.obolibrary.org/obo/PR_000001838 T-cell surface glycoprotein CD1 A T-cell surface glycoprotein CD1 that is a translation product of the human CD1C gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000002028 antigen-presenting glycoprotein CD1d http://purl.obolibrary.org/obo/PR_000001838 T-cell surface glycoprotein CD1 A T-cell surface glycoprotein CD1 that is a translation product of the human CD1D gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000002030 alpha-type platelet-derived growth factor receptor http://purl.obolibrary.org/obo/PR_000001810 CSF-1/PDGF receptor-type tyrosine-protein kinase A CSF-1/PDGF receptor-type tyrosine-protein kinase that is a translation product of the human PDGFRA gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000002031 aminopeptidase N http://purl.obolibrary.org/obo/PR_000001888 membrane alanyl aminopeptidase-like metallopeptidase A membrane alanyl aminopeptidase-like metallopeptidase that is a translation product of the human ANPEP gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000002037 complement component C1q receptor http://purl.obolibrary.org/obo/PR_000001938 thrombomodulin-like receptor A thrombomodulin-like receptor that is a translation product of the human CD93 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000002039 glutamyl aminopeptidase http://purl.obolibrary.org/obo/PR_000001888 membrane alanyl aminopeptidase-like metallopeptidase A membrane alanyl aminopeptidase-like metallopeptidase that is a translation product of the human ENPEP gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000002062 macrophage colony-stimulating factor 1 receptor http://purl.obolibrary.org/obo/PR_000001810 CSF-1/PDGF receptor-type tyrosine-protein kinase A CSF-1/PDGF receptor-type tyrosine-protein kinase that is a translation product of the human CSF1R gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000002064 macrosialin http://purl.obolibrary.org/obo/PR_000001883 lysosome-associated membrane protein A lysosome-associated membrane protein that is a translation product of the human CD68 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000002065 mast/stem cell growth factor receptor http://purl.obolibrary.org/obo/PR_000001810 CSF-1/PDGF receptor-type tyrosine-protein kinase A CSF-1/PDGF receptor-type tyrosine-protein kinase that is a translation product of the human KIT gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000002097 sodium channel protein type 11 subunit alpha http://purl.obolibrary.org/obo/PR_000001975 voltage-gated sodium channel subunit alpha A voltage-gated sodium channel subunit alpha that is a translation product of the human SCN11A gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000002104 sodium channel protein type 9 subunit alpha http://purl.obolibrary.org/obo/PR_000001975 voltage-gated sodium channel subunit alpha A voltage-gated sodium channel subunit alpha that is a translation product of the human SCN9A gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000002105 thrombomodulin http://purl.obolibrary.org/obo/PR_000001938 thrombomodulin-like receptor A thrombomodulin-like receptor that is a translation product of the human THBD gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000002112 vascular endothelial growth factor receptor 2 http://purl.obolibrary.org/obo/PR_000001971 vascular endothelial growth factor receptor A vascular endothelial growth factor receptor that is a translation product of the human KDR gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000002123 C-C motif chemokine 3 http://purl.obolibrary.org/obo/PR_000001998 C-C motif chemokine 3/4 A C-C motif chemokine 3/4 that is a translation product of the human CCL3 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000002972 macrophage mannose receptor 1 http://purl.obolibrary.org/obo/PR_000001025 C-type lectin with multiple lectin domains A C-type lectin with multiple lectin domains that is a translation product of the human MRC1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000002976 Ly-6-like protein http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is the translation product of any of the LY6 genes (LY6A-LY6I). http://purl.obolibrary.org/obo/PR_000002977 killer cell lectin-like receptor subfamily B member 1C http://purl.obolibrary.org/obo/PR_000001874 KLRB1-like protein A KLRB1-like protein that is a translation product of the mouse Klrb1c gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000002978 lymphocyte antigen 6G http://purl.obolibrary.org/obo/PR_000002976 Ly-6-like protein An Ly-6-like protein that is a translation product of the mouse Ly6g gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000002979 lymphocyte antigen 6A-2/6E-1 http://purl.obolibrary.org/obo/PR_000002976 Ly-6-like protein An Ly-6-like protein that is a translation product of the mouse Ly6a gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000002980 lymphocyte antigen 6C2 http://purl.obolibrary.org/obo/PR_000002976 Ly-6-like protein An Ly-6-like protein that is a translation product of the mouse Ly6c2 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000002981 lymphocyte antigen 76 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A protein that is a translation product of the Ly76 gene in mouse. http://purl.obolibrary.org/obo/PR_000003262 collagen alpha chain http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a component of collagen. Collagens are trimeric molecules in which each chain comprises a repeating Gly-X-Y triplet, in which X and Y can be any residue but are usually proline and hydroxyproline, respectively. This results in a left-handed helix that combines with other two to form a triple-helical structure. http://purl.obolibrary.org/obo/PR_000003263 collagen type I alpha chain http://purl.obolibrary.org/obo/PR_000003262 collagen alpha chain A collagen alpha chain that is a translation product of the human COL1A1 or COL1A2 genes, 1:1 orthologs thereof, or a semi-ortholog thereof. http://purl.obolibrary.org/obo/PR_000003264 collagen alpha-1(I) chain http://purl.obolibrary.org/obo/PR_000003263 collagen type I alpha chain A collagen type I alpha chain that is a translation product of the human COL1A1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000003328 collagen alpha-1(III) chain http://purl.obolibrary.org/obo/PR_000003262 collagen alpha chain A collagen alpha chain that is a translation product of the human COL3A1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000003353 collagen alpha-1(VI) chain http://purl.obolibrary.org/obo/PR_000003386 collagen type VI alpha chain A collagen type VI alpha chain that is a translation product of the human COL6A1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000003386 collagen type VI alpha chain http://purl.obolibrary.org/obo/PR_000003262 collagen alpha chain A collagen alpha chain that is a translation product of the human COL6A1, COL6A2, or COL6A3 genes, 1:1 orthologs thereof, or a semi-ortholog thereof. http://purl.obolibrary.org/obo/PR_000018264 proteolytic cleavage product http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is produced as the result of proteolytic processing of a longer protein. http://purl.obolibrary.org/obo/PR_000018798 collagen alpha-1(I) chain proteolytic cleavage product http://purl.obolibrary.org/obo/PR_000018264 proteolytic cleavage product A collagen alpha-1(I) chain that has been processed by proteolytic cleavage. http://purl.obolibrary.org/obo/PR_000025796 integrin alpha http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is composed of a long N-terminal extracellular domain, a transmembrane domain and a short cytoplasmic C-terminal domain. The N-terminal domain contains beta-propeller repeats (interrupted by an A domain in a subset of integrins alpha), while the C-terminal domain contains a GFFxR motif. http://purl.obolibrary.org/obo/PR_000030035 G-protein coupled receptor http://purl.obolibrary.org/obo/PR_000000001 protein A protein that has G protein-coupled receptor (GPCR) activity. Each GPCR consists of a single polypeptide with an extracellular N-terminus, an intracellular C-terminus and seven hydrophobic transmembrane domains (TM1-TM7) linked by three extracellular loops (ECL1-ECL3) and three intracellular loops (ICL1-ICL3). GPCRs function as part of a heterotrimeric complex to transmit an extracellular signal across the membrane by activating an associated G-protein via the exchange of GDP for GTP on the alpha subunit. http://purl.obolibrary.org/obo/PR_000036194 eukaryotic protein http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is encoded in the genome of some Eukaryota. http://purl.obolibrary.org/obo/PR_000037069 glycoprotein http://purl.obolibrary.org/obo/PR_000000001 protein A protein that includes at least one glycosylated residue. http://purl.obolibrary.org/obo/PR_000040662 cathepsin-like protease http://purl.obolibrary.org/obo/PR_000036194 eukaryotic protein A protein that is a translation product of some metazoan gene that encodes a signal peptide followed by a single Cathepsin propeptide inhibitor domain (Pfam:PF08246) followed by a single Papain family cysteine protease (Pfam:PF00112) domain at the C terminus. http://purl.obolibrary.org/obo/PR_000021081 bone marrow proteoglycan, signal peptide removed form http://purl.obolibrary.org/obo/PR_000013206 bone marrow proteoglycan A bone marrow proteoglycan that has had the signal peptide removed. http://purl.obolibrary.org/obo/PR_000021082 bone marrow proteoglycan proteolytic cleavage product http://purl.obolibrary.org/obo/PR_000013206 bone marrow proteoglycan A bone marrow proteoglycan that has been processed by proteolytic cleavage. http://purl.obolibrary.org/obo/PR_000021083 proteoglycan 4 proteolytic cleavage product http://purl.obolibrary.org/obo/PR_000013208 proteoglycan 4 A proteoglycan 4 that has been processed by proteolytic cleavage. http://purl.obolibrary.org/obo/PR_000021172 parathyroid hormone-related protein proteolytic cleavage product http://purl.obolibrary.org/obo/PR_000013433 parathyroid hormone-related protein A parathyroid hormone-related protein that has been processed by proteolytic cleavage. http://purl.obolibrary.org/obo/PR_000021468 sonic hedgehog protein proteolytic cleavage product http://purl.obolibrary.org/obo/PR_000018264 proteolytic cleavage product A sonic hedgehog protein that has been processed by proteolytic cleavage. http://purl.obolibrary.org/obo/PR_000021578 somatostatin proteolytic cleavage product http://purl.obolibrary.org/obo/PR_000018264 proteolytic cleavage product A somatostatin that has been processed by proteolytic cleavage. http://purl.obolibrary.org/obo/PR_000021619 protachykinin-1 proteolytic cleavage product http://purl.obolibrary.org/obo/PR_000018264 proteolytic cleavage product A protachykinin-1 that has been processed by proteolytic cleavage. http://purl.obolibrary.org/obo/PR_000021620 tachykinin-3 proteolytic cleavage product http://purl.obolibrary.org/obo/PR_000018264 proteolytic cleavage product A tachykinin-3 that has been processed by proteolytic cleavage. http://purl.obolibrary.org/obo/PR_000021826 vasoactive intestinal polypeptides proteolytic cleavage product http://purl.obolibrary.org/obo/PR_000018264 proteolytic cleavage product A VIP peptides that has been processed by proteolytic cleavage. http://purl.obolibrary.org/obo/PR_000022003 bone marrow proteoglycan isoform 1 http://purl.obolibrary.org/obo/PR_000013206 bone marrow proteoglycan A bone marrow proteoglycan that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P13727-1 or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000022006 eosinophil granule major basic protein http://purl.obolibrary.org/obo/PR_000025466 bone marrow proteoglycan isoform 1, signal peptide removed form A bone marrow proteoglycan isoform 1, signal peptide removed form that has had the acidic propeptide removed. http://purl.obolibrary.org/obo/PR_000025403 T-cell surface glycoprotein CD8 alpha chain isoform 1 http://purl.obolibrary.org/obo/PR_000001084 T-cell surface glycoprotein CD8 alpha chain A T-cell surface glycoprotein CD8 alpha chain that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P01732-1 or a 1:1 ortholog thereof. Having a single-pass transmembrane domain, this form is membrane bound. http://purl.obolibrary.org/obo/PR_000025405 T-cell surface glycoprotein CD8 beta chain isoform 1 http://purl.obolibrary.org/obo/PR_000001085 T-cell surface glycoprotein CD8 beta chain A T-cell surface glycoprotein CD8 beta chain that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P10966-1 or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000025406 T-cell surface glycoprotein CD8 alpha chain isoform 1, signal peptide removed form http://purl.obolibrary.org/obo/PR_000025403 T-cell surface glycoprotein CD8 alpha chain isoform 1 A T-cell surface glycoprotein CD8 alpha chain isoform 1 that has had the signal peptide removed to yield the mature form. http://purl.obolibrary.org/obo/PR_000025407 T-cell surface glycoprotein CD8 beta chain isoform 1, signal peptide removed form http://purl.obolibrary.org/obo/PR_000025405 T-cell surface glycoprotein CD8 beta chain isoform 1 A T-cell surface glycoprotein CD8 beta chain isoform 1 that has had the signal peptide removed to yield the mature form. http://purl.obolibrary.org/obo/PR_000025408 T-cell surface glycoprotein CD8 alpha chain isoform 1, signal peptide removed glycosylated form http://purl.obolibrary.org/obo/PR_000025406 T-cell surface glycoprotein CD8 alpha chain isoform 1, signal peptide removed form A T-cell surface glycoprotein CD8 alpha chain isoform 1, signal peptide removed form that includes at least one glycosylated residue. http://purl.obolibrary.org/obo/PR_000025409 T-cell surface glycoprotein CD8 beta chain isoform 1, signal peptide removed glycosylated form http://purl.obolibrary.org/obo/PR_000025407 T-cell surface glycoprotein CD8 beta chain isoform 1, signal peptide removed form A T-cell surface glycoprotein CD8 beta chain isoform 1, signal peptide removed form that includes at least one glycosylated residue. http://purl.obolibrary.org/obo/PR_000025420 collagen alpha-1(VI) chain proteolytic cleavage product http://purl.obolibrary.org/obo/PR_000018264 proteolytic cleavage product A collagen alpha-1(VI) chain that has been processed by proteolytic cleavage. http://purl.obolibrary.org/obo/PR_000025455 CD2 molecule proteolytic cleavage product http://purl.obolibrary.org/obo/PR_000018264 proteolytic cleavage product A CD2 molecule that has been processed by proteolytic cleavage. http://purl.obolibrary.org/obo/PR_000025466 bone marrow proteoglycan isoform 1, signal peptide removed form http://purl.obolibrary.org/obo/PR_000022003 bone marrow proteoglycan isoform 1 A bone marrow proteoglycan isoform 1 that has had the signal peptide removed. http://purl.obolibrary.org/obo/PR_000025670 killer cell lectin-like receptor subfamily B member 1 http://purl.obolibrary.org/obo/PR_000001874 KLRB1-like protein A KLRB1-like protein that is a translation product of the human KLRB1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000027222 CALCA gene translation product http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CALCA gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000027223 CALCA gene translation product (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A CALCA gene translation product that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_000027226 calcitonin gene-related peptide 1 http://purl.obolibrary.org/obo/PR_000027222 CALCA gene translation product A CALCA gene translation product that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P06881-1 or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein http://purl.obolibrary.org/obo/PR_000036194 eukaryotic protein A protein that is encoded in the genome of Mus musculus. http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein http://purl.obolibrary.org/obo/PR_000036194 eukaryotic protein A protein that is encoded in the genome of Homo sapiens. http://purl.obolibrary.org/obo/PR_P10747 T-cell-specific surface glycoprotein CD28 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A T-cell-specific surface glycoprotein CD28 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P11215 integrin alpha-M (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein An integrin alpha-M that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P38570 integrin alpha-E (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein An integrin alpha-E that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_O95817 BAG family molecular chaperone regulator 3 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A BAG family molecular chaperone regulator 3 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P01732 T-cell surface glycoprotein CD8 alpha chain (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A T-cell surface glycoprotein CD8 alpha chain that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P02452 collagen alpha-1(I) chain (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A collagen alpha-1(I) chain that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P02461 collagen alpha-1(III) chain (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A collagen alpha-1(III) chain that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P02786 transferrin receptor protein 1 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A transferrin receptor protein 1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P03372 estrogen receptor (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein An estrogen receptor that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P06126 T-cell surface glycoprotein CD1a (human) http://purl.obolibrary.org/obo/PR_000036947 T-cell surface glycoprotein CD1 (human) A T-cell surface glycoprotein CD1a that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P06307 cholecystokinin (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A cholecystokinin that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P06729 T-cell surface antigen CD2 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A CD2 molecule that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P07451 carbonic anhydrase 3 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A carbonic anhydrase 3 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P07766 T-cell surface glycoprotein CD3 epsilon chain (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A CD3 epsilon that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P07949 proto-oncogene tyrosine-protein kinase receptor Ret (human) http://purl.obolibrary.org/obo/PR_000013895 proto-oncogene tyrosine-protein kinase receptor Ret A proto-oncogene tyrosine-protein kinase receptor Ret that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P08473 neprilysin (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A neprilysin that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P08670 vimentin (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A vimentin that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P09581 macrophage colony-stimulating factor 1 receptor (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A macrophage colony-stimulating factor 1 receptor that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P10147 C-C motif chemokine 3 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A C-C motif chemokine 3 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P10242 transcriptional activator Myb (human) http://purl.obolibrary.org/obo/PR_000010799 myb proto-oncogene protein A myb proto-oncogene protein that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P10966 T-cell surface glycoprotein CD8 beta chain (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A T-cell surface glycoprotein CD8 beta chain that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P12107 collagen alpha-1(XI) chain (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A collagen alpha-1(XI) chain that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P12109 collagen alpha-1(VI) chain (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A collagen alpha-1(VI) chain that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P13686 tartrate-resistant acid phosphatase type 5 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A tartrate-resistant acid phosphatase type 5 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P15144 aminopeptidase N (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein An aminopeptidase N that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P15391 B-lymphocyte antigen CD19 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A CD19 molecule that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P15813 antigen-presenting glycoprotein CD1d (human) http://purl.obolibrary.org/obo/PR_000036947 T-cell surface glycoprotein CD1 (human) An antigen-presenting glycoprotein CD1d that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P16070 CD44 antigen (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A CD44 molecule that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P16671 platelet glycoprotein 4 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A platelet glycoprotein 4 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P17542 T-cell acute lymphocytic leukemia protein 1 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A T-cell acute lymphocytic leukemia protein 1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P20138 myeloid cell surface antigen CD33 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A CD33 molecule that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P20273 B-cell receptor CD22 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A B-cell receptor CD22 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P21728 D(1A) dopamine receptor (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A D(1A) dopamine receptor that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P21926 CD9 antigen (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A CD9 molecule that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P22091 T-cell acute lymphocytic leukemia protein 1 homolog (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A T-cell acute lymphocytic leukemia protein 1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P26842 CD27 antigen (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A CD27 molecule that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P27797 calreticulin (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A calreticulin that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P29017 T-cell surface glycoprotein CD1c (human) http://purl.obolibrary.org/obo/PR_000036947 T-cell surface glycoprotein CD1 (human) A T-cell surface glycoprotein CD1c that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P30530 tyrosine-protein kinase receptor UFO (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A tyrosine-protein kinase receptor UFO that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P32248 C-C chemokine receptor type 7 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A C-C chemokine receptor type 7 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P33151 cadherin-5 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A cadherin-5 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P33681 T-lymphocyte activation antigen CD80 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A CD80 molecule that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P35968 vascular endothelial growth factor receptor 2 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A vascular endothelial growth factor receptor 2 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P36544 neuronal acetylcholine receptor subunit alpha-7 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A neuronal acetylcholine receptor subunit alpha-7 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P42081 T-lymphocyte activation antigen CD86 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A CD86 molecule that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P49715 CCAAT/enhancer-binding protein alpha (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A CCAAT/enhancer-binding protein alpha that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_Q00653 nuclear factor NF-kappa-B p100 subunit (human) http://purl.obolibrary.org/obo/PR_000011178 nuclear factor NF-kappa-B p100 subunit A nuclear factor NF-kappa-B p100 subunit that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_Q03692 collagen alpha-1(X) chain (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A collagen alpha-1(X) chain that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_Q13291 signaling lymphocytic activation molecule (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A SLAM family member 1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_Q16602 calcitonin gene-related peptide type 1 receptor (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A calcitonin gene-related peptide type 1 receptor that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_Q86VB7 scavenger receptor cysteine-rich type 1 protein M130 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A scavenger receptor cysteine-rich type 1 protein M130 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_Q8NER1 transient receptor potential cation channel subfamily V member 1 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A transient receptor potential cation channel TRPV1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_Q99259 glutamate decarboxylase 1 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A glutamate decarboxylase 1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_Q9BXN2 C-type lectin domain family 7 member A (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A C-type lectin domain family 7 member A that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_Q9BZS1 forkhead box protein P3 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A forkhead box protein P3 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_Q9BZW8 natural killer cell receptor 2B4 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A natural killer cell receptor 2B4 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_Q9UIB8 SLAM family member 5 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A SLAM family member 5 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_O00253 agouti-related protein (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein An agouti-related protein that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_O09100 endothelial transcription factor GATA-2 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein An endothelial transcription factor GATA-2 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_O14638 ectonucleotide pyrophosphatase/phosphodiesterase family member 3 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein An ectonucleotide pyrophosphatase/phosphodiesterase family member 3 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_O14770 homeobox protein Meis2 (human) http://purl.obolibrary.org/obo/PR_000010317 homeobox protein Meis2 A homeobox protein Meis2 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_O15353 forkhead box protein N1 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A forkhead box protein N1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P16297 interleukin-2 receptor subunit beta (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein An interleukin-2 receptor subunit beta that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P16406 glutamyl aminopeptidase (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A glutamyl aminopeptidase that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P16444 dipeptidase 1 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A dipeptidase 1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P16872 interleukin-7 receptor subunit alpha (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein An interleukin-7 receptor subunit alpha that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P17208 POU domain, class 4, transcription factor 1 (mouse) http://purl.obolibrary.org/obo/PR_000013041 POU domain, class 4, transcription factor 1 A POU domain, class 4, transcription factor 1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P17433 transcription factor PU.1 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A transcription factor PU.1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P17679 erythroid transcription factor (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein An erythroid transcription factor that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P17813 endoglin (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein An endoglin that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P17947 transcription factor PU.1 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A transcription factor PU.1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P18181 CD48 antigen (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A CD48 molecule that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P18337 L-selectin (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein An L-selectin that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P18828 syndecan-1 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A syndecan-1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P19070 complement receptor type 2 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A complement receptor type 2 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P19246 neurofilament heavy polypeptide (mouse) http://purl.obolibrary.org/obo/PR_000011118 neurofilament heavy polypeptide A neurofilament heavy polypeptide that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P19437 B-lymphocyte antigen CD20 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A membrane-spanning 4-domains subfamily A member 1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P19785 estrogen receptor (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein An estrogen receptor that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P20023 complement receptor type 2 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A complement receptor type 2 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P20152 vimentin (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A vimentin that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P20366 protachykinin-1 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A protachykinin-1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P20472 parvalbumin alpha (human) http://purl.obolibrary.org/obo/PR_000013502 parvalbumin alpha A parvalbumin alpha that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P20489 high affinity immunoglobulin epsilon receptor subunit alpha (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A high affinity immunoglobulin epsilon receptor subunit alpha that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P20693 low affinity immunoglobulin epsilon Fc receptor (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A low affinity immunoglobulin epsilon Fc receptor that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P20718 granzyme H (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A granzyme H that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P20937 T-cell surface glycoprotein YE1/48 (mouse) http://purl.obolibrary.org/obo/PR_000009616 T-cell surface glycoprotein YE1/48 A T-cell surface glycoprotein YE1/48 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P21183 interleukin-5 receptor subunit alpha (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein An interleukin-5 receptor subunit alpha that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P21462 fMet-Leu-Phe receptor (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein An fMet-Leu-Phe receptor that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P21757 macrophage scavenger receptor types I and II (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A macrophage scavenger receptor types I and II that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P21784 V(D)J recombination-activating protein 2 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A V(D)J recombination-activating protein 2 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P22005 proenkephalin-A (mouse) http://purl.obolibrary.org/obo/PR_000012544 proenkephalin-A A proenkephalin-A that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P22083 alpha-(1,3)-fucosyltransferase 4 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein An alpha-(1,3)-fucosyltransferase 4 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P22387 endothelin-1 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein An endothelin-1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P22466 galanin peptides (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A galanin that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P22646 T-cell surface glycoprotein CD3 epsilon chain (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A CD3 epsilon that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P22676 calretinin (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A calretinin that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P22858 parathyroid hormone-related protein (mouse) http://purl.obolibrary.org/obo/PR_000013433 parathyroid hormone-related protein A parathyroid hormone-related protein that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P23769 endothelial transcription factor GATA-2 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein An endothelial transcription factor GATA-2 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P23772 trans-acting T-cell-specific transcription factor GATA-3 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A trans-acting T-cell-specific transcription factor GATA-3 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P24529 tyrosine 3-monooxygenase (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A tyrosine 3-monooxygenase that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P55075 fibroblast growth factor 8 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A fibroblast growth factor 8 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P55097 cathepsin K (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A cathepsin K that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P55099 tachykinin-3 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A tachykinin-3 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P55284 cadherin-5 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A cadherin-5 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P55772 ectonucleoside triphosphate diphosphohydrolase 1 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein An ectonucleoside triphosphate diphosphohydrolase 1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P55895 V(D)J recombination-activating protein 2 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A V(D)J recombination-activating protein 2 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P56373 P2X purinoceptor 3 (human) http://purl.obolibrary.org/obo/PR_000012190 P2X purinoceptor 3 A P2X purinoceptor 3 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P56473 agouti-related protein (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein An agouti-related protein that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P56528 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein An ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P57774 pro-neuropeptide Y (mouse) http://purl.obolibrary.org/obo/PR_000011387 neuropeptide Y A neuropeptide Y that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P58462 forkhead box protein P1 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A forkhead box protein P1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P60041 somatostatin (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A somatostatin that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P61073 C-X-C chemokine receptor type 4 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A C-X-C chemokine receptor type 4 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P61148 fibroblast growth factor 1 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A fibroblast growth factor 1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P61168 D(2) dopamine receptor (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A D(2) dopamine receptor that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P61278 somatostatin (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A somatostatin that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P62736 actin, aortic smooth muscle (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein An actin, aortic smooth muscle that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P62737 actin, aortic smooth muscle (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein An actin, aortic smooth muscle that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P63015 paired box protein Pax-6 (mouse) http://purl.obolibrary.org/obo/PR_000012318 paired box protein Pax-6 A paired box protein Pax-6 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q12918 killer cell lectin-like receptor subfamily B member 1 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A killer cell lectin-like receptor subfamily B member 1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_Q13241 natural killer cells antigen CD94 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A killer cell lectin-like receptor subfamily D member 1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_Q13445 transmembrane emp24 domain-containing protein 1 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A transmembrane emp24 domain-containing protein 1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_Q14246 adhesion G protein-coupled receptor E1 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein An adhesion G protein-coupled receptor E1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_Q14515 SPARC-like protein 1 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A SPARC-like protein 1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_Q15063 periostin (human) http://purl.obolibrary.org/obo/PR_000013031 periostin A periostin that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_Q15465 sonic hedgehog protein (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A sonic hedgehog protein that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_Q15726 metastasis-suppressor KiSS-1 (human) http://purl.obolibrary.org/obo/PR_000009344 metastasis-suppressor KiSS-1 A metastasis-suppressor KiSS-1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_Q15744 CCAAT/enhancer-binding protein epsilon (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A CCAAT/enhancer-binding protein epsilon that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_Q15858 sodium channel protein type 9 subunit alpha (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A sodium channel protein type 9 subunit alpha that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_Q16572 vesicular acetylcholine transporter (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A vesicular acetylcholine transporter that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_Q18PI6 SLAM family member 5 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A SLAM family member 5 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q62205 sodium channel protein type 9 subunit alpha (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A sodium channel protein type 9 subunit alpha that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q62230 sialoadhesin (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A sialoadhesin that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q62233 homeobox protein SIX3 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A homeobox protein SIX3 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q62351 transferrin receptor protein 1 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A transferrin receptor protein 1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q62469 integrin alpha-2 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein An integrin alpha-2 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q63961 endoglin (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein An endoglin that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q63994 myeloid cell surface antigen CD33 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A CD33 molecule that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q64237 dopamine beta-hydroxylase (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A dopamine beta-hydroxylase that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q64314 hematopoietic progenitor cell antigen CD34 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A CD34 molecule that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q64329 killer cell lectin-like receptor 3 (mouse) http://purl.obolibrary.org/obo/PR_000009618 killer cell lectin-like receptor 3 A killer cell lectin-like receptor 3 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q67BJ4 lactosylceramide 4-alpha-galactosyltransferase (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A lactosylceramide 4-alpha-galactosyltransferase that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q8BJI4 POU domain, class 6, transcription factor 2 (mouse) http://purl.obolibrary.org/obo/PR_000013047 POU domain, class 6, transcription factor 2 A POU domain, class 6, transcription factor 2 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q8BLE7 vesicular glutamate transporter 2 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A vesicular glutamate transporter 2 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q8C567 natural cytotoxicity triggering receptor 1 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A natural cytotoxicity triggering receptor 1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q8CD54 piezo-type mechanosensitive ion channel component 2 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A piezo-type mechanosensitive ion channel component 2 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q99JA0-1 calcitonin gene-related peptide 1 (mouse) http://purl.obolibrary.org/obo/PR_000027226 calcitonin gene-related peptide 1 A calcitonin gene-related peptide 1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q99JB6 forkhead box protein P3 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A forkhead box protein P3 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q99NH8 triggering receptor expressed on myeloid cells 2 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A triggering receptor expressed on myeloid cells 2 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q99PV8 B-cell lymphoma/leukemia 11B (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A B-cell lymphoma/leukemia 11B that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q9H334 forkhead box protein P1 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A forkhead box protein P1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_Q9H5I5 piezo-type mechanosensitive ion channel component 2 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A piezo-type mechanosensitive ion channel component 2 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_Q9H9P2 chondrolectin (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A chondrolectin that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_Q9HBX9 relaxin receptor 1 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A relaxin receptor 1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_Q9JIP3 interleukin-17 receptor B (mouse) http://purl.obolibrary.org/obo/PR_000008982 interleukin-17 receptor B An interleukin-17 receptor B that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q9JKD8 T-box transcription factor TBX21 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A T-box transcription factor TBX21 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q9JKF4 C-type lectin domain family 6 member A (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A C-type lectin domain family 6 member A that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q9UBR4 LIM/homeobox protein Lhx3 (human) http://purl.obolibrary.org/obo/PR_000009793 LIM/homeobox protein Lhx3 A LIM/homeobox protein Lhx3 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_Q9UEW3 macrophage receptor MARCO (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A macrophage receptor MARCO that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_Q9UHF0 tachykinin-3 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A tachykinin-3 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_Q9UHM6 melanopsin (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A melanopsin that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_Q9UI33 sodium channel protein type 11 subunit alpha (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A sodium channel protein type 11 subunit alpha that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_Q9UIK5 tomoregulin-2 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A tomoregulin-2 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_Q9UJ71 C-type lectin domain family 4 member K (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A C-type lectin domain family 4 member K that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_Q9UJQ1 lysosome-associated membrane glycoprotein 5 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A lysosome-associated membrane glycoprotein 5 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_Q9UL17 T-box transcription factor TBX21 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A T-box transcription factor TBX21 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_Q9UPM6 LIM/homeobox protein Lhx6 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A LIM/homeobox protein Lhx6 that is encoded in the genome of human. http://purl.obolibrary.org/obo/CL_0008024 pancreatic endocrine cell http://purl.obolibrary.org/obo/CL_0000164 enteroendocrine cell An endocrine cell that is part of the pancreas. http://purl.obolibrary.org/obo/CL_0011115 precursor cell http://purl.obolibrary.org/obo/CL_0000000 cell A cell that, by division or terminal differentiation, can give rise to other cell types. http://purl.obolibrary.org/obo/GO_0140029 exocytic process http://purl.obolibrary.org/obo/GO_0009987 cellular process The cellular processes that contribute to exocytosis. http://purl.obolibrary.org/obo/GO_0140039 cell-cell adhesion in response to extracellular stimulus http://purl.obolibrary.org/obo/GO_0098609 cell-cell adhesion The attachment of one cell to another cell via adhesion molecules as a result of an extracellular stimulus. http://purl.obolibrary.org/obo/GO_0099161 regulation of presynaptic dense core granule exocytosis http://purl.obolibrary.org/obo/GO_0099171 presynaptic modulation of chemical synaptic transmission Any process that modulates the frequency, rate or extent of presynaptic dense core granule exocytosis. http://purl.obolibrary.org/obo/GO_0099170 postsynaptic modulation of chemical synaptic transmission http://purl.obolibrary.org/obo/GO_0050804 modulation of chemical synaptic transmission Any process, acting in the postsynapse that results in modulation of chemical synaptic transmission. http://purl.obolibrary.org/obo/GO_0099171 presynaptic modulation of chemical synaptic transmission http://purl.obolibrary.org/obo/GO_0050804 modulation of chemical synaptic transmission Any process, acting in the presynapse that results in modulation of chemical synaptic transmission. http://purl.obolibrary.org/obo/GO_0099172 presynapse organization http://purl.obolibrary.org/obo/GO_0016043 cellular component organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a presynapse. http://purl.obolibrary.org/obo/GO_0099175 regulation of postsynapse organization http://purl.obolibrary.org/obo/GO_0050807 regulation of synapse organization Any process that modulates the physical form of a postsynapse. http://purl.obolibrary.org/obo/GO_0106135 negative regulation of cardiac muscle cell contraction http://purl.obolibrary.org/obo/GO_0055118 negative regulation of cardiac muscle contraction Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle cell contraction. http://purl.obolibrary.org/obo/GO_0120192 tight junction assembly http://purl.obolibrary.org/obo/GO_0007043 cell-cell junction assembly A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a tight junction. A tight junction seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other. http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure A part of a cellular organism consisting of a material entity with granularity above the level of a protein complex but below that of an anatomical system. Note that cellular organisms exclude viruses. http://purl.obolibrary.org/obo/PATO_0070001 neurogliaform morphology http://purl.obolibrary.org/obo/PATO_0070026 multipolar neuron morphology A cell morphology that inheres in neurons which have a small round soma, a large number of short, smooth, or slightly beaded primary dendrites that give rise to only a few secondary branches, and a branched axon that establishes a dense axonal mesh with thin shafts. http://purl.obolibrary.org/obo/GO_0120308 axonemal outer doublet assembly http://purl.obolibrary.org/obo/GO_0022607 cellular component assembly The aggregation, arrangement and bonding together of a set of components to form an axonemal outer doublet, a part of an axoneme consisting of a doublet microtubule. http://purl.obolibrary.org/obo/CL_4023040 L2/3-6 intratelencephalic projecting glutamatergic neuron http://purl.obolibrary.org/obo/CL_4023008 intratelencephalic-projecting glutamatergic cortical neuron An intratelencephalic-projecting glutamatergic neuron with a soma found in cortical layers L2/3-6. http://purl.obolibrary.org/obo/CL_4023049 L5 intratelencephalic projecting glutamatergic neuron of the primary motor cortex http://purl.obolibrary.org/obo/CL_4030064 L5 intratelencephalic projecting glutamatergic neuron An intratelencephalic-projecting glutamatergic neuron with a soma found in L5 of the primary motor cortex. http://purl.obolibrary.org/obo/CL_4023086 T Martinotti neuron http://purl.obolibrary.org/obo/CL_4023076 Martinotti neuron A Martinotti neuron that has axons that form a horizontal ramification, making it T-shaped. http://purl.obolibrary.org/obo/CL_4023065 meis2 expressing cortical GABAergic cell http://purl.obolibrary.org/obo/CL_0010012 cerebral cortex neuron A GABAergic cell located in the cerebral cortex that expresses meis2. http://purl.obolibrary.org/obo/GO_0140667 regulation of oxytocin production http://purl.obolibrary.org/obo/GO_0010468 regulation of gene expression Any process that modulates the frequency, rate, or extent of production of oxytocin. http://purl.obolibrary.org/obo/UBERON_0039222 cystic artery http://purl.obolibrary.org/obo/UBERON_0015796 liver blood vessel An artery that supplies oxygenated blood to the cystic duct. http://purl.obolibrary.org/obo/UBERON_7500062 tibial tuberosity http://purl.obolibrary.org/obo/UBERON_4100000 skeletal element projection The tibial tuberosity is on the anterior side of a tibia and is where a patella ligament attaches. http://purl.obolibrary.org/obo/UBERON_8410003 ductal plate http://purl.obolibrary.org/obo/UBERON_0010000 multicellular anatomical structure In human, ductal plate is a double-layered cylindrical structure of bile duct epithelium that surrounds the portal ramifications by the eighth gestational week. After approximately the 12th gestational week, remodelling of ductal plate begins, and maturity is attained by the end of gestation or early postnatal period. http://purl.obolibrary.org/obo/UBERON_8410020 venule of appendix http://purl.obolibrary.org/obo/UBERON_0001979 venule A venule located in the vermiform appendix. http://purl.obolibrary.org/obo/UBERON_8410028 arteriole of appendix http://purl.obolibrary.org/obo/UBERON_0001980 arteriole An arteriole located in the vermiform appendix. http://purl.obolibrary.org/obo/UBERON_8410030 lymphatic vessel of appendix http://purl.obolibrary.org/obo/UBERON_0001473 lymphatic vessel A lymphatic vessel located in the vermiform appendix. http://purl.obolibrary.org/obo/UBERON_8410037 high endothelial venule http://purl.obolibrary.org/obo/UBERON_0035428 postcapillary venule High endothelial venules are specialized blood vessels adapted for lymphocyte trafficking. They form a spatially organized network, which controls both the type of lymphocyte and the site of entry into lymphoid tissues. Uniquely, high endothelial venules express vascular addressins that regulate lymphocyte entry into lymphoid organs. They perform this function in all lymphoid organs except the spleen. http://purl.obolibrary.org/obo/UBERON_8410039 high endothelial venule of appendix http://purl.obolibrary.org/obo/UBERON_8410037 high endothelial venule A high endothelial venule that is located in the vermiform appendix. http://purl.obolibrary.org/obo/UBERON_8410040 high endothelial venule of small intestine Peyer's patch http://purl.obolibrary.org/obo/UBERON_8410037 high endothelial venule A high endothelial venule that is located in a Peyer's patch in the small intestine. http://purl.obolibrary.org/obo/UBERON_8410044 vein of appendix http://purl.obolibrary.org/obo/UBERON_0001638 vein A vein that is part of a vermiform appendix. http://purl.obolibrary.org/obo/UBERON_8410045 artery of appendix http://purl.obolibrary.org/obo/UBERON_0001637 artery An artery that is part of a vermiform appendix. http://purl.obolibrary.org/obo/UBERON_8410049 serosal nerve fiber of appendix http://purl.obolibrary.org/obo/UBERON_0006134 nerve fiber A nerve fiber that is located in the serosa of vermiform appendix. http://purl.obolibrary.org/obo/UBERON_8420000 hair of scalp http://purl.obolibrary.org/obo/UBERON_0016446 hair of head Hair that grows on the scalp. http://purl.obolibrary.org/obo/PATO_0070044 anatomical structure quality http://purl.obolibrary.org/obo/PATO_0001241 physical object quality A quality of continuant that exist at the anatomical level of organisation and anything under it. This includes, but is not limited to, cells , tissues, and components. http://purl.obolibrary.org/obo/PATO_0070045 anatomical histological quality http://purl.obolibrary.org/obo/PATO_0070044 anatomical structure quality A quality inhering in an anotomical structure by virtue of its capacity to be stained by specific histological dyes. http://purl.obolibrary.org/obo/PATO_0070046 neutrophillic http://purl.obolibrary.org/obo/PATO_0070045 anatomical histological quality An affinity inhering in an anatomical structure by virtue of the bearer exhibiting a molecular interaction that stains and colors, pale-pink, with Wright-Giemsa stain. http://purl.obolibrary.org/obo/PATO_0070047 polychromatophilic http://purl.obolibrary.org/obo/PATO_0070045 anatomical histological quality An affinity inhering in an anatomical structure by virtue of the bearer exhibiting a molecular interaction for both basic and acid stains under specific pH conditions. http://purl.obolibrary.org/obo/UBERON_8450001 egg follicle http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure An individual reproductive unit containing a single oocyte and one or several layers of support cells (Armstrong et al., 2020). http://purl.obolibrary.org/obo/CL_0009091 Leydig stem cell http://purl.obolibrary.org/obo/CL_0000034 stem cell A stem cell found in the interstitial compartment of the neonatal testis; it is capable of self-renewal as well as differentiation into steroidogenic cells (adult Leydig cells). Intermediate stages of development include progenitor Leydig cells and immature Leydig cells. http://purl.obolibrary.org/obo/CL_0009099 fibro/adipogenic progenitor cell http://purl.obolibrary.org/obo/CL_0008019 mesenchymal cell A progenitor cell that is a tissue-resident mesenchymal cell, important for skeletal muscle regeneration, and able to differentiate into both adipocytes or fibroblasts. http://purl.obolibrary.org/obo/CL_0009115 lymph node lymphatic vessel endothelial cell http://purl.obolibrary.org/obo/CL_0002138 endothelial cell of lymphatic vessel An endothelial cell located in a lymph node lymphatic vessel. http://purl.obolibrary.org/obo/CL_0009116 progenitor cell of mammary luminal epithelium http://purl.obolibrary.org/obo/CL_0011026 progenitor cell A progenitor cell with the potential to differentiate into luminal epithelial cells of mammary glands. In mouse, CD61 and c-kit were found to be coexpressed by the majority of, but not all, committed luminal progenitor cells. http://purl.obolibrary.org/obo/PATO_0040072 high nuclear/cytoplasmic ratio http://purl.obolibrary.org/obo/PATO_0001396 cellular quality A quality inhering in a cell by virtue of the cell having a high nuclear/cytoplasmic ratio. http://purl.obolibrary.org/obo/UBERON_7500107 sphenovomerine suture http://purl.obolibrary.org/obo/UBERON_0009199 facial suture A suture joining a sphenoid bone with the alae of a vomer to form a schindylesis type of joint. http://purl.obolibrary.org/obo/CL_0003002 G1 retinal ganglion cell http://purl.obolibrary.org/obo/CL_0000740 retinal ganglion cell A retinal ganglion cell that has a small dendritic field and a medium dendritic arbor with post sympatic terminals in sublaminar layer S3. http://purl.obolibrary.org/obo/CL_4023064 caudal ganglionic eminence derived interneuron http://purl.obolibrary.org/obo/CL_0010011 cerebral cortex GABAergic interneuron An interneuron that is derived from the caudal ganglionic eminence. http://purl.obolibrary.org/obo/UBERON_8480026 skin of iliac crest region http://purl.obolibrary.org/obo/UBERON_0001415 skin of pelvis A zone of skin that is above the iliac crest in the pelvic girdle bone/zone. http://purl.obolibrary.org/obo/UBERON_8480030 skin of breast http://purl.obolibrary.org/obo/UBERON_0001868 skin of chest A zone of skin that is part of the breast. http://purl.obolibrary.org/obo/UBERON_8480037 subserosa of fallopian tube http://purl.obolibrary.org/obo/UBERON_0012375 subserosa Subserosa that is part of the uterine tube. It contains loose connective tissue, blood vessels and lymphatic tissue. http://purl.obolibrary.org/obo/UBERON_8600038 placental disc http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure A disc-shaped structure that is part of the placenta. A placental disc supports fetal development through the exchange of nutrients between maternal and fetal bloodstreams. The placental disc is structured to keep the blood streams separate, while maximizing surface area for the transport of nutrients between them, to maintain an immunological barrier. http://purl.obolibrary.org/obo/CL_4307033 Astro-NT NN_1 Mecom astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301589 Astro-NT NN_1 astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Dao (Mmus), Mecom (Mmus), Fbln5 (Mmus), Prelp (Mmus). It is distinguished from other Astro-NT NN_1 cells by expression of Mecom, Prelp. These cells are located in the Medulla, Cerebellum, brain , in or close to the regions: Ventral cochlear nucleus, Paraflocculus, Flocculus, Dorsal cochlear nucleus . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5213 Astro-NT NN_1. http://purl.obolibrary.org/obo/CL_4307041 Astro-TE NN_1 Jph4 astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301591 Astro-TE NN_1 astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Myoc (Mmus), Sptbn2 (Mmus), Alpk1 (Mmus). It is distinguished from other Astro-TE NN_1 cells by expression of Myoc, Jph4, Alpk1. It is glutamatergic (inferred from expression of Aldh1a1, Slc17a7). These cells are located in the Isocortex, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5221 Astro-TE NN_1. http://purl.obolibrary.org/obo/CL_4307028 Astro-NT NN_1 Galnt15 astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301589 Astro-NT NN_1 astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gfap (Mmus), Galnt15 (Mmus), Agt (Mmus). It is distinguished from other Astro-NT NN_1 cells by expression of Galnt15. These cells are located in the Cerebellum, brain , in or close to the regions: arbor vitae . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5208 Astro-NT NN_1. http://purl.obolibrary.org/obo/CL_4301589 Astro-NT NN_1 astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4300358 subcortical astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gfap (Mmus), Lhfpl3 (Mmus), Gria1 (Mmus), Hopx (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1159 Astro-NT NN_1. http://purl.obolibrary.org/obo/CL_4072013 A16 dopaminergic neuron http://purl.obolibrary.org/obo/CL_1001434 olfactory bulb interneuron A type of dopaminergic interneuron located in the glomerular layer of the main olfactory bulb, characterized by the co-release of dopamine and GABA, and involved in modulating sensory input within olfactory circuits. http://purl.obolibrary.org/obo/CL_4072011 A14 dopaminergic neuron http://purl.obolibrary.org/obo/CL_2000029 central nervous system neuron A type of dopaminergic neuron located in the periventricular nucleus of the hypothalamus and projecting to the lateral septum and the median eminence. It is contributing to neuroendocrine functions, locomotion and stress regulation. http://purl.obolibrary.org/obo/CL_4072102 Purkinje layer interneuron http://purl.obolibrary.org/obo/CL_4023057 cerebellar inhibitory GABAergic interneuron A type of GABAergic interneuron residing in the Purkinje cell layer of the cerebellar cortex. http://purl.obolibrary.org/obo/CL_4301611 commited oligodendrocyte precursor (Mmus) http://purl.obolibrary.org/obo/CL_4300367 oligodendrocyte (Mmus) A committed oligodendrocyte precursor of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gpr17 (Mmus), Bmp4 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1181 COP NN_1. http://purl.obolibrary.org/obo/CL_4033136 inferior mesenteric ganglion SP neuron http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron A sympathetic neuron that has the soma located in the inferior mesenteric ganglion and expresses the marker substance P (SP). http://purl.obolibrary.org/obo/CL_4300360 olfactory areas astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_0000127 astrocyte A transcriptomically defined type of astrocyte located exclusively in the olfactory areas. It is distinguished from other cells in the brain by selective expression of Gja1 (Mmus), Hs3st3a1 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Subclass:320 Astro-OLF NN. http://purl.obolibrary.org/obo/CL_4307069 beta1-tancyte (Mmus) http://purl.obolibrary.org/obo/CL_4301603 Tanycyte NN_2 tanycyte (Mmus) A beta1-tanycyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gpr50 (Mmus), Frzb (Mmus), Foxd2os (Mmus). It is distinguished from other Tanycyte NN_2 cells by expression of Col25a1, C230072F16Rik. These cells are located in the Hypothalamus, brain , in or close to the regions: third ventricle, Arcuate hypothalamic nucleus . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5249 Tanycyte NN_2. http://purl.obolibrary.org/obo/CL_4301571 DCO Il22 Gly-Gaba_1 cerebellar neuron (Mmus) http://purl.obolibrary.org/obo/CL_4300348 DCO Il22 Gly-Gaba cerebellar neuron (Mmus) A cerebellar neuron of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Il22 (Mmus), Rftn1 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1141 DCO Il22 Gly-Gaba_1. http://purl.obolibrary.org/obo/CL_4307085 CHOR NN_1 Slc17a8 choroid plexus epithelial cell (Mmus) http://purl.obolibrary.org/obo/CL_4301608 choroid plexus epithelial cell (Mmus) A choroid plexus epithelial cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of 2900040C04Rik (Mmus), Slc17a8 (Mmus). It is distinguished from other CHOR NN cells by expression of Slc17a8. It is glutamatergic (inferred from expression of Slc17a8). These cells are located in the brain , in or close to the regions: choroid plexus, lateral ventricle . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5265 CHOR NN_1. http://purl.obolibrary.org/obo/CL_4307053 Astro-OLF NN_2 Slc25a34 astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301597 Astro-OLF NN_2 astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Aqp4 (Mmus), Hs3st3a1 (Mmus), Slc25a34 (Mmus), C4b (Mmus). It is distinguished from other Astro-OLF NN_2 cells by expression of Slc25a34, C4b. These cells are located in the Olfactory areas, brain , in or close to the regions: Main olfactory bulb, outer plexiform layer, Main olfactory bulb . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5233 Astro-OLF NN_2. http://purl.obolibrary.org/obo/CL_4307086 OPC NN_1 Neil3 oligodendrocyte precursor cell (Mmus) http://purl.obolibrary.org/obo/CL_4300366 oligodendrocyte precursor cell (Mmus) A oligodendrocyte precursor cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Pdgfra (Mmus), Pclaf (Mmus), Mki67 (Mmus), Foxg1 (Mmus). It is distinguished from other OPC NN_1 cells by expression of Neil3, Foxg1. These cells are located in the Isocortex, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5266 OPC NN_1. http://purl.obolibrary.org/obo/CL_4307109 OEC NN_1 Adamts12 olfactory ensheathing cell (Mmus) http://purl.obolibrary.org/obo/CL_4301615 olfactory ensheathing cell (Mmus) A olfactory ensheathing cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Cldn5 (Mmus), Adamts12 (Mmus). It is distinguished from other OEC cells by expression of Adamts12. These cells are located in the brain , in or close to the regions: olfactory nerve layer of main olfactory bulb . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5289 OEC NN_1. http://purl.obolibrary.org/obo/CL_4300101 STR D1 Gaba direct pathway medium spiny neuron (Mmus) http://purl.obolibrary.org/obo/CL_4023026 direct pathway medium spiny neuron A direct pathway medium spiny neuron of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Prkch (Mmus), Slc32a1 (Mmus), Drd1 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Subclass:061 STR D1 Gaba. http://purl.obolibrary.org/obo/GO_0160274 beige fat cell differentiation http://purl.obolibrary.org/obo/GO_0045444 fat cell differentiation The process in which a white fat cell acquires specialized features of a beige adipocyte. Beige adipocytes reside within white adipose tissue and can be induced to produce heat in response to cold exposure or certain stimuli, resembling brown adipocytes. http://purl.obolibrary.org/obo/GO_7770012 negative regulation of starch biosynthetic process http://purl.obolibrary.org/obo/GO_0045912 negative regulation of carbohydrate metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of starch. http://purl.obolibrary.org/obo/CL_0020000 gut mesenchymal lymphoid tissue organizer cell http://purl.obolibrary.org/obo/CL_0011026 progenitor cell A mesenchymal stromal cell found in the gut during development, and interacts with lymphoid tissue inducer (LTi) cells to drive secondary lymphoid organ formation (Prados et al., 2021). It expresses LTβR, PDGFRα, and VCAM, and upon activation secretes chemokines(e.g. CXCL13) and cytokines to organise lymphoid tissue architecture and recruit immune cells in both mice and humans (Denton el al., 2019; Elmentaite et al., 2021). As a multipotent progenitor, an mLTo cell differentiates into adult stromal subsets, including fibroblastic reticular cells (FRCs) (Prados et al., 2021), and its descendants persist in the adult gut-associated lymphoid tissues to maintain immune homeostasis(Denton el al., 2019; Lütge et al., 2021). http://purl.obolibrary.org/obo/CL_0020001 V1delta gamma-delta T cell http://purl.obolibrary.org/obo/CL_0000800 mature gamma-delta T cell A mature gamma-delta T Cell with T cell receptors consisting of the Vδ1 segment paired with various V gamma chains. This cell is enriched in the gut, skin (Davey et al., 2018) and the female reproductive tract (Wu et al., 2022). It exhibits potent cytotoxic capabilities through perforin/granzyme and death receptor pathways. http://purl.obolibrary.org/obo/CL_0020002 mucosal-associated invariant T cell, human http://purl.obolibrary.org/obo/CL_0000940 mucosal-associated invariant T cell A mucosal-associated invariant T (MAIT) cell found in various tissues including human blood, liver, gut, and lung, characterised by a semi-invariant T cell receptor (TCR) comprising TRAV1-2 (Vα7.2) predominantly paired with TRAJ33, and high expression of CD161. Upon activation, MAIT cells produce inflammatory cytokines, including IFN-γ, TNF-α, and IL-17. http://purl.obolibrary.org/obo/CL_0020003 internal globus pallidus core projecting neuron http://purl.obolibrary.org/obo/CL_0012001 neuron of the forebrain A projection neuron that has its soma located in the internal segment of the globus pallidus (GPi) of primates, in the central “core” region. It expresses parvalbumin, is primarily GABAergic, and projects to motor thalamic nuclei including the ventral anterior, ventrolateral, and ventromedial nuclei. In the rodent homolog (entopeduncular nucleus), the core subregion is characterized by concentrated parvalbumin-positive neurons targeting the ventral anterior-ventral lateral thalamic nucleus and receives inputs from the dorsolateral striatum innervated by sensorimotor cortices (Miyamoto & Fukuda, 2022). This neuron corresponds to the sensorimotor output population of the GPi, as demonstrated in human tissue and cross-species comparative studies (Wallace et al., 2017) and by classic tracing in primates (Parent & De Bellefeuille, 1982; Parent et al., 2001). http://purl.obolibrary.org/obo/CL_0020004 internal globus pallidus shell projection neuron http://purl.obolibrary.org/obo/CL_0012001 neuron of the forebrain A projection neuron that has its soma located in the internal segment of the globus pallidus (GPi), in the peripheral 'shell' region. In mice and primates, it expresses somatostatin and shows dual expression of GABAergic and glutamatergic markers, enabling co-release of GABA and glutamate (Wallace et al., 2017). It projects primarily to the lateral habenula (Parent & De Bellefeuille, 1982; Wallace et al., 2017), forming the limbic/aversive output stream of the GPi. http://purl.obolibrary.org/obo/CL_0020005 spiral ligament fibrocyte http://purl.obolibrary.org/obo/CL_0002665 otic fibrocyte An otic fibrocyte that is part of the spiral ligament. This cell is crucial in maintaining the endocochlear potential, regulating blood flow, participating in immune responses by secreting chemokines including MCP-1 and MIP-2, and producing extracellular matrix proteins such as collagen and cochlin. http://purl.obolibrary.org/obo/CL_0020006 OB-Dopa-GABA http://purl.obolibrary.org/obo/CL_0002613 striatum neuron A transcriptomically defined GABAergic neuron coexpressing dopamine located in the olfactory bulb and part of the striatum. http://purl.obolibrary.org/obo/CL_0020007 dorso-striatal cholinergic-GABAergic neuron http://purl.obolibrary.org/obo/CL_0008061 GABA-Chol neuron A transcriptomically defined GABAergic neuron in the dorsal striatum. In mice and primates, it is defined by the coexpression of choline acetyltransferase (ChAT) together with the GABAergic markers glutamate decarboxylase 65 (GAD65/Gad2) and vesicular GABA transporter (VGAT/Slc32a1) (Lozovaya et al., 2018). http://purl.obolibrary.org/obo/CL_0020008 striatal cholinergic-GABAergic neuron http://purl.obolibrary.org/obo/CL_0008061 GABA-Chol neuron A large aspiny interneuron of the striatum that serves as the principal intrinsic source of acetylcholine while simultaneously releasing GABA. It is defined by coexpression of cholinergic markers (ChAT and VAChT/Slc18a3) and GABAergic markers (GAD65/Gad2 and VGAT/Slc32a1) (Lozovaya et al., 2018). This MGE-derived neuron maintains Lhx6 expression associated with dual-transmitter identity (Fragkouli et al., 2009; Marin et al., 2000). Morphologically, it possesses a large soma (20–50 μm diameter), 2–4 thick aspiny dendrites extending radially ~1 mm, and locally ramified axons with hundreds of thousands of varicosities (Wilson et al., 1990; Lim et al., 2014). http://purl.obolibrary.org/obo/CL_0020009 prototypic neuron http://purl.obolibrary.org/obo/CL_0012001 neuron of the forebrain A GABAergic neuron located in the external globus pallidus (GPe) that constitutes approximately two-thirds of all GPe neurons (Mallet et al., 2012, Dodson et al., 2015). Derived from the medial ganglionic eminence, this cell selectively expresses Nkx2-1, with roughly two-thirds co-expressing parvalbumin (PV) and one-third lacking it in mice (Mallet et al., 2012; Dodson et al., 2015). http://purl.obolibrary.org/obo/CL_0020010 arkypallidal neuron http://purl.obolibrary.org/obo/CL_0012001 neuron of the forebrain A GABAergic projection neuron located in the external segment of the globus pallidus (GPe) and defined by its exclusive projection to the dorsal striatum rather than to the subthalamic nucleus or basal ganglia output nuclei. In rodents and primates, it is characterized molecularly by expression of FOXP2, MEIS2, and NPAS1, and lacks expression of canonical pallidal markers NKX2-1 and LHX6 (Dodson et al., 2015; Abdi et al., 2015; Courtney et al., 2023). This neuron is GABAergic (GAD1/2⁺, SLC32A1/VGAT⁺) and typically PV⁻, forming the transcriptionally and developmentally LGE-derived subclass of GPe neurons (Dodson et al., 2015; Mallet et al., 2012). http://purl.obolibrary.org/obo/CL_7770004 suprabasal cell http://purl.obolibrary.org/obo/CL_0000066 epithelial cell An epithelial cell that resides in the layer(s) immediately above the basal layer in stratified or pseudostratified epithelia. This cell mainly originates from basal cells and is found across various tissues, including skin, esophagus, oral mucosa, airway, and cornea. http://purl.obolibrary.org/obo/CL_4033098 inner wall Schlemm's canal endothelial cell http://purl.obolibrary.org/obo/CL_4033097 Schlemm's canal endothelial cell A Schlemm's canal endothelial cell that lines the inner wall of the Schlemm's canal. This cell exhibits a cobblestone appearance due to the significant biomechanical load it experiences, as well as the segmental flow of aqueous humor. The degree of biomechanical stress can lead to the formation of dome-like outpouchings known as giant vacuoles. In addition, the cell contains transcellular pores that mediate aqueous humor transport (Dautriche et al., 2015). This endothelial cell also displays prominent peripheral F-actin bands which help maintain structural integrity under pressure (Ethier et al., 2004). http://purl.obolibrary.org/obo/CL_4033099 outer wall Schlemm's canal endothelial cell http://purl.obolibrary.org/obo/CL_4033097 Schlemm's canal endothelial cell A Schlemm's canal endothelial cell that lines the outer wall of the Schlemm's canal. This cell displays a smooth and flat morphology (Dautriche et al., 2015) and it is distinguished by the presence of Weibel-Palade bodies, specialized organelles that produce, store, and release P-Selectin (Hamanaka et al., 1992). This endothelial cell also exhibits stellate (star-shaped) actin arrangements distributed throughout much of the cell (Ethier et al., 2004). http://purl.obolibrary.org/obo/CL_4033100 atrial intrinsic cardiac ganglion TH neuron http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron A sympathetic neuron that has the soma located in the atrial intrinsic cardiac ganglion and expresses the marker tyrosine hydroxylase (TH). http://purl.obolibrary.org/obo/CL_4033101 superior cervical ganglion TH/DBH neuron http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron A sympathetic neuron that has the soma located in the superior cervical ganglion and expresses the marker tyrosine hydroxylase (TH) and dopamine beta-hydroxylase (DBH). http://purl.obolibrary.org/obo/CL_4033104 superior cervical ganglion TH/NPY neuron http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron A sympathetic neuron that has the soma located in the superior cervical ganglion and expresses the marker tyrosine hydroxylase (TH) and neuropeptide Y (NPY). http://purl.obolibrary.org/obo/CL_4033106 superior cervical ganglion VIP neuron http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron A sympathetic neuron that has the soma located in the superior cervical ganglion and expresses the marker vasoactive intestinal peptide (VIP). http://purl.obolibrary.org/obo/CL_4033107 superior cervical ganglion CGRP neuron http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron A sympathetic neuron that has the soma located in the superior cervical ganglion and expresses the marker calcitonin gene-related peptide (CGRP). http://purl.obolibrary.org/obo/CL_4033108 middle cervical ganglion DBH neuron http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron A sympathetic neuron that has the soma located in the middle cervical ganglion and expresses the marker dopamine beta-hydroxylase (DBH). http://purl.obolibrary.org/obo/CL_4033109 middle cervical ganglion TH neuron http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron A sympathetic neuron that has the soma located in the middle cervical ganglion and expresses the marker tyrosine hydroxylase (TH). http://purl.obolibrary.org/obo/CL_4033110 middle cervical ganglion TH/NPY neuron http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron A sympathetic neuron that has the soma located in the middle cervical ganglion and expresses the marker tyrosine hydroxylase (TH) and neuropeptide Y (NPY). http://purl.obolibrary.org/obo/CL_4033111 middle cervical ganglion NPY neuron http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron A sympathetic neuron that has the soma located in the middle cervical ganglion and expresses the marker neuropeptide Y (NPY). http://purl.obolibrary.org/obo/CL_4033112 middle cervical ganglion VIP neuron http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron A sympathetic neuron that has the soma located in the middle cervical ganglion and expresses the marker vasoactive intestinal peptide (VIP). http://purl.obolibrary.org/obo/CL_4033113 cervicothoracic ganglion enkephalin neuron http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron A sympathetic neuron that has the soma located in the cervicothoracic ganglion and expresses the marker enkephalin. http://purl.obolibrary.org/obo/CL_4033114 cervicothoracic ganglion TH neuron http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron A sympathetic neuron that has the soma located in the cervicothoracic ganglion and expresses the marker tyrosine hydroxylase (TH). http://purl.obolibrary.org/obo/CL_4033115 cervicothoracic ganglion TH/NPY neuron http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron A sympathetic neuron that has the soma located in the cervicothoracic ganglion and expresses the marker tyrosine hydroxylase (TH) and neuropeptide Y (NPY). http://purl.obolibrary.org/obo/CL_4033116 cervicothoracic ganglion VIP neuron http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron A sympathetic neuron that has the soma located in the cervicothoracic ganglion and expresses the marker vasoactive intestinal peptide (VIP). http://purl.obolibrary.org/obo/CL_4033117 cervicothoracic ganglion VAChT neuron http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron A sympathetic neuron that has the soma located in the cervicothoracic ganglion and expresses the marker vesicular acetylcholine transporter (VAChT). http://purl.obolibrary.org/obo/CL_4033118 thoracic ganglion enkephalin neuron http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron A sympathetic neuron that has the soma located in the thoracic ganglion and expresses the marker enkephalin. http://purl.obolibrary.org/obo/CL_4033119 thoracic ganglion TH neuron http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron A sympathetic neuron that has the soma located in the thoracic ganglion and expresses the marker tyrosine hydroxylase (TH). http://purl.obolibrary.org/obo/CL_4033120 thoracic ganglion TH/NPY neuron http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron A sympathetic neuron that has the soma located in the thoracic ganglion and expresses the marker tyrosine hydroxylase (TH) and neuropeptide Y (NPY). http://purl.obolibrary.org/obo/CL_4033121 lumbar ganglion VIP neuron http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron A sympathetic neuron that has the soma located in the lumbar ganglion and expresses the marker vasoactive intestinal peptide (VIP). http://purl.obolibrary.org/obo/CL_4033122 lumbar ganglion SST/TH neuron http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron A sympathetic neuron that has the soma located in the lumbar ganglion and expresses the marker somatostatin (SST) and tyrosine hydroxylase (TH). http://purl.obolibrary.org/obo/CL_4033123 lumbar ganglion TH/NPY neuron http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron A sympathetic neuron that has the soma located in the lumbar ganglion and expresses the marker tyrosine hydroxylase (TH) and neuropeptide Y (NPY). http://purl.obolibrary.org/obo/CL_4033124 lumbar ganglion TH neuron http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron A sympathetic neuron that has the soma located in the lumbar ganglion and expresses the marker tyrosine hydroxylase (TH). http://purl.obolibrary.org/obo/CL_4033125 lumbar ganglion NPY neuron http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron A sympathetic neuron that has the soma located in the lumbar ganglion and expresses the marker neuropeptide Y (NPY). http://purl.obolibrary.org/obo/CL_4033127 lower airway ganglion ChAT/VIP neuron http://purl.obolibrary.org/obo/CL_0011102 parasympathetic neuron A parasympathetic neuron that has the soma located in the lower airway ganglion and expresses the marker choline O-acetyltransferase (ChAT) and vasoactive intestinal peptide (VIP). http://purl.obolibrary.org/obo/CL_4033128 celiac ganglion VIP neuron http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron A sympathetic neuron that has the soma located in the celiac ganglion and expresses the marker vasoactive intestinal peptide (VIP). http://purl.obolibrary.org/obo/CL_4033129 celiac ganglion PHI neuron http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron A sympathetic neuron that has the soma located in the celiac ganglion and expresses the marker peptide histidine isoleucine (PHI). http://purl.obolibrary.org/obo/CL_4033130 celiac ganglion CGRP neuron http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron A sympathetic neuron that has the soma located in the celiac ganglion and expresses the marker calcitonin gene-related peptide (CGRP). http://purl.obolibrary.org/obo/CL_4033131 celiac ganglion SP neuron http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron A sympathetic neuron that has the soma located in the celiac ganglion and expresses the marker substance P (SP). http://purl.obolibrary.org/obo/CL_4033132 celiac ganglion SOM neuron http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron A sympathetic neuron that has the soma located in the celiac ganglion and expresses the marker somatostatin (SOM). http://purl.obolibrary.org/obo/CL_4033133 celiac ganglion SOM/CGRP neuron http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron A sympathetic neuron that has the soma located in the celiac ganglion and expresses the marker somatostatin (SOM) and calcitonin gene-related peptide (CGRP). http://purl.obolibrary.org/obo/CL_4033134 superior mesenteric ganglion SP neuron http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron A sympathetic neuron that has the soma located in the superior mesenteric ganglion and expresses the marker substance P (SP). http://purl.obolibrary.org/obo/CL_4033135 inferior mesenteric ganglion TH neuron http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron A sympathetic neuron that has the soma located in the inferior mesenteric ganglion and expresses the marker tyrosine hydroxylase (TH). http://purl.obolibrary.org/obo/CL_4033137 otic ganglion nNOS neuron http://purl.obolibrary.org/obo/CL_0011102 parasympathetic neuron A parasympathetic neuron that has the soma located in the otic ganglion and expresses the marker neuronal nitric oxide synthase 1 (nNOS). http://purl.obolibrary.org/obo/CL_4033138 otic ganglion VIP neuron http://purl.obolibrary.org/obo/CL_0011102 parasympathetic neuron A parasympathetic neuron that has the soma located in the otic ganglion and expresses the marker vasoactive intestinal peptide (VIP). http://purl.obolibrary.org/obo/CL_4033139 ciliary ganglion VIP/PHI neuron http://purl.obolibrary.org/obo/CL_0011102 parasympathetic neuron A parasympathetic postganglionic neuron whose soma is located in the ciliary ganglion and that co-expresses vasoactive intestinal peptide (VIP) and peptide histidine isoleucine (PHI, both encoded by the VIP gene). This neuron provides parasympathetic innervation to the eye, contributing to regulation of pupillary constriction and ciliary muscle accommodation. It has been identified in human ciliary ganglia by immunohistochemistry (Kiyokawa et al. 2012, PMID:22095632). VIP/PHI co-expression distinguishes this subpopulation from other cholinergic parasympathetic neurons in the ciliary ganglion and is characteristic of a subset of cranial parasympathetic neurons in humans and other mammals. http://purl.obolibrary.org/obo/CL_4033140 ciliary ganglion TH neuron http://purl.obolibrary.org/obo/CL_0011102 parasympathetic neuron A parasympathetic neuron that has the soma located in the ciliary ganglion and expresses the marker tyrosine hydroxylase (TH). http://purl.obolibrary.org/obo/CL_4033141 submandibular ganglion TH cholinergic neuron http://purl.obolibrary.org/obo/CL_0011102 parasympathetic neuron A parasympathetic neuron that has the soma located in the submandibular ganglion and expresses the marker tyrosine hydroxylase (TH). http://purl.obolibrary.org/obo/CL_4033142 submandibular ganglion VIP/PHI neuron http://purl.obolibrary.org/obo/CL_0011102 parasympathetic neuron A parasympathetic neuron that has the soma located in the submandibular ganglion and expresses the marker vasoactive intestinal peptide (VIP) and peptide histidine isoleucine (PHI). http://purl.obolibrary.org/obo/CL_4033143 submandibular ganglion nNOS neuron http://purl.obolibrary.org/obo/CL_0011102 parasympathetic neuron A parasympathetic neuron that has the soma located in the submandibular ganglion and expresses the marker neuronal nitric oxide synthase 1 (nNOS). http://purl.obolibrary.org/obo/CL_4033144 pterygopalatine ganglion VIP/PHI neuron http://purl.obolibrary.org/obo/CL_0011102 parasympathetic neuron A parasympathetic neuron that has the soma located in the pterygopalatine ganglion and expresses the marker vasoactive intestinal peptide (VIP) and peptide histidine isoleucine (PHI). http://purl.obolibrary.org/obo/CL_4033145 pterygopalatine ganglion VIP neuron http://purl.obolibrary.org/obo/CL_0011102 parasympathetic neuron A parasympathetic neuron that has the soma located in the pterygopalatine ganglion and expresses the marker vasoactive intestinal peptide (VIP). http://purl.obolibrary.org/obo/CL_4033146 pterygopalatine ganglion nNOS neuron http://purl.obolibrary.org/obo/CL_0011102 parasympathetic neuron A parasympathetic neuron that has the soma located in the pterygopalatine ganglion and expresses the marker neuronal nitric oxide synthase 1 (nNOS). http://purl.obolibrary.org/obo/CL_4033147 vestibular ganglion SP neuron http://purl.obolibrary.org/obo/CL_0000101 sensory neuron A sensory neuron that has the soma located in the vestibular ganglion and expresses the marker substance P (SP). http://purl.obolibrary.org/obo/CL_4033148 nodose ganglion TRPV1 neuron http://purl.obolibrary.org/obo/CL_0000101 sensory neuron A sensory neuron that has the soma located in the nodose ganglion and expresses the marker transient receptor potential vanilloid 1 (TRPV1). http://purl.obolibrary.org/obo/CL_4033149 nodose ganglion P2X3 neuron http://purl.obolibrary.org/obo/CL_0000101 sensory neuron A sensory neuron that has the soma located in the nodose ganglion and expresses the marker purinergic receptor P2X3 (P2X3). http://purl.obolibrary.org/obo/CL_4033153 jugular ganglion TRPV2 neuron http://purl.obolibrary.org/obo/CL_0000101 sensory neuron A sensory neuron that has the soma located in the jugular ganglion and expresses the marker transient receptor potential vanilloid 2 (TRPV2). http://purl.obolibrary.org/obo/CL_4033154 jugular ganglion SP neuron http://purl.obolibrary.org/obo/CL_0000101 sensory neuron A sensory neuron that has the soma located in the jugular ganglion and expresses the marker substance P (SP). http://purl.obolibrary.org/obo/CL_4033155 jugular ganglion CGRP neuron http://purl.obolibrary.org/obo/CL_0000101 sensory neuron A sensory neuron that has the soma located in the jugular ganglion and expresses the marker calcitonin gene-related peptide (CGRP). http://purl.obolibrary.org/obo/CL_4033157 geniculate ganglion TRPV1 neuron http://purl.obolibrary.org/obo/CL_0000101 sensory neuron A sensory neuron that has the soma located in the geniculate ganglion and expresses the marker transient receptor potential vanilloid 1 (TRPV1). http://purl.obolibrary.org/obo/CL_4033158 geniculate ganglion SPARCL1 neuron http://purl.obolibrary.org/obo/CL_0000101 sensory neuron A sensory neuron that has the soma located in the geniculate ganglion and expresses the marker SPARC-like protein 1 (SPARCL1). http://purl.obolibrary.org/obo/CL_4033159 geniculate ganglion VGLUT2 neuron http://purl.obolibrary.org/obo/CL_0000101 sensory neuron A sensory neuron that has the soma located in the geniculate ganglion and expresses the marker vesicular glutamate transporter 2 (VGLUT2). http://purl.obolibrary.org/obo/CL_4033160 myenteric ganglion of small intestine ChAT neuron http://purl.obolibrary.org/obo/CL_0020057 cholinergic neuron of myenteric plexus An enteric neuron that has the soma located in the myenteric ganglion of the small intestine and expresses the marker choline O-acetyltransferase (ChAT). http://purl.obolibrary.org/obo/CL_4033161 myenteric ganglion of small intestine nNOS neuron http://purl.obolibrary.org/obo/CL_0007011 enteric neuron An enteric neuron that has the soma located in the myenteric ganglion of the small intestine and expresses the marker neuronal nitric oxide synthase 1 (nNOS). http://purl.obolibrary.org/obo/CL_4033162 myenteric ganglion of small intestine VIP neuron http://purl.obolibrary.org/obo/CL_0007011 enteric neuron An enteric neuron that has the soma located in the myenteric ganglion of the small intestine and expresses the marker vasoactive intestinal peptide (VIP). http://purl.obolibrary.org/obo/CL_4033163 myenteric ganglion of small intestine nNOS/VIP neuron http://purl.obolibrary.org/obo/CL_0007011 enteric neuron An enteric neuron that has the soma located in the myenteric ganglion of the small intestine and expresses the marker neuronal nitric oxide synthase 1 (nNOS) and vasoactive intestinal peptide (VIP). http://purl.obolibrary.org/obo/CL_4033164 myenteric ganglion of small intestine nNOS/ChAT neuron http://purl.obolibrary.org/obo/CL_0007011 enteric neuron An enteric neuron that has the soma located in the myenteric ganglion of the small intestine and expresses the marker neuronal nitric oxide synthase 1 (nNOS) and choline O-acetyltransferase (ChAT). http://purl.obolibrary.org/obo/CL_4033165 myenteric ganglion of small intestine ChAT/CALR/SOM/SP neuron http://purl.obolibrary.org/obo/CL_0007011 enteric neuron An enteric neuron that has the soma located in the myenteric ganglion of the small intestine and expresses the marker choline acetyltransferase (ChAT), calretinin (CALR), somatostatin (SOM), and substance P (SP). http://purl.obolibrary.org/obo/CL_4033166 myenteric ganglion of small intestine VIP/GAL neuron http://purl.obolibrary.org/obo/CL_0007011 enteric neuron An enteric neuron that has the soma located in the myenteric ganglion of the small intestine and expresses the marker vasoactive intestinal peptide (VIP) and galanin (GAL). http://purl.obolibrary.org/obo/CL_4033167 pelvic ganglion TH neuron http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron A sympathetic neuron that has the soma located in the pelvic ganglion and expresses the marker tyrosine hydroxylase (TH). http://purl.obolibrary.org/obo/CL_4033168 pelvic ganglion TH/DBH neuron http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron A sympathetic neuron that has the soma located in the pelvic ganglion and expresses the marker tyrosine hydroxylase (TH) and dopamine beta-hydroxylase (DBH). http://purl.obolibrary.org/obo/CL_4033169 pelvic ganglion VAChT neuron http://purl.obolibrary.org/obo/CL_0011102 parasympathetic neuron A parasympathetic neuron that has the soma located in the pelvic ganglion and expresses the marker vesicular acetylcholine transporter (VAChT). http://purl.obolibrary.org/obo/CL_4033170 pelvic ganglion nNOS neuron http://purl.obolibrary.org/obo/CL_0011102 parasympathetic neuron A parasympathetic neuron that has the soma located in the pelvic ganglion and expresses the marker neuronal nitric oxide synthase 1 (nNOS). http://purl.obolibrary.org/obo/CL_4033171 pelvic ganglion nNOS/VIP neuron http://purl.obolibrary.org/obo/CL_0011102 parasympathetic neuron A parasympathetic neuron that has the soma located in the pelvic ganglion and expresses the marker neuronal nitric oxide synthase (nNOS) 1 and vasoactive intestinal peptide (VIP). http://purl.obolibrary.org/obo/CL_4033172 pelvic ganglion NPY/VAChT neuron http://purl.obolibrary.org/obo/CL_0011102 parasympathetic neuron A parasympathetic neuron that has the soma located in the pelvic ganglion and expresses the marker neuropeptide Y (NPY) and vesicular acetylcholine transporter (VAChT). http://purl.obolibrary.org/obo/CL_4033173 pelvic ganglion nNOS/VAChT neuron http://purl.obolibrary.org/obo/CL_0011102 parasympathetic neuron A parasympathetic neuron that has the soma located in the pelvic ganglion and expresses the marker neuronal nitric oxide synthase 1(nNOS) and vesicular acetylcholine transporter (VAChT). http://purl.obolibrary.org/obo/CL_4033174 ovarian nerve plexus ganglion TH neuron http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron A sympathetic neuron that has the soma located in the ovarian nerve plexus ganglion and expresses the marker tyrosine hydroxylase (TH). http://purl.obolibrary.org/obo/CL_4052062 onychofibroblast http://purl.obolibrary.org/obo/CL_0002620 skin fibroblast A specialized fibroblast located in the onychodermis that play a key role in nail growth and regeneration by interacting with LGR6-positive nail matrix keratinocytes. These interactions mediate essential signaling pathways, particularly WNT signaling, which is critical for epithelial–mesenchymal communication and coordinated nail development. In humans, this cell expresses key markers, including RSPO4, MSX1, WIF1, and BMP5, all involved in nail differentiation. http://purl.obolibrary.org/obo/CL_4052063 nail bed keratinocyte http://purl.obolibrary.org/obo/CL_4052061 epidermal keratinocyte A keratinocyte that resides in the nail bed, responsible for tightly attaching the nail plate to the underlying dermis. Unlike typical epidermal keratinocytes, it exhibits limited proliferation, undergoes modified differentiation that skips the granular layer and conventional cornification, and primarily ensures adhesion and maintenance of the nail plate. In humans, this cell expresses characteristic markers, including the protease inhibitor SPINK6 and the differentiation-associated protein KRT16. http://purl.obolibrary.org/obo/CL_4052064 nail matrix keratinocyte http://purl.obolibrary.org/obo/CL_4052061 epidermal keratinocyte A keratinocyte that is part of the nail matrix epithelium, distinguished by its high proliferative capacity and its role in nail plate formation via onychokeratinization, a differentiation process that uniquely bypasses the formation of a granular layer, resulting in the production of hard, compact keratin. Unlike skin epidermal keratinocytes, this cell expresses a distinctive mix of hard (hair-type) and select epidermal keratins (Kitahara and Ogawa, 1993). In humans, LGR6 and WNT6 are enriched in the basal compartment, with LGR6 marking nail stem cells in both mice and humans, and exhibiting strong expression in the human proximal nail matrix (Kim et al., 2021). http://purl.obolibrary.org/obo/CL_4052065 serous acinar cell of salivary gland http://purl.obolibrary.org/obo/CL_0020059 serous demilune cell of salivary gland An acinar cell of the salivary gland, characterized by a pyramidal or triangular shape with a spherical nucleus and abundant eosinophilic zymogen granules. This cell secretes watery, enzyme‐rich fluid containing α-amylase, proline-rich proteins, and secretory immunoglobulins for starch digestion and antimicrobial defence. In humans and mice, serous acinar cell predominates in the parotid gland and to a lesser extent in the submandibular gland, where it exists alongside mucous acinar cells (Maruyama et al., 2019). http://purl.obolibrary.org/obo/CL_4052066 mucous acinar cell of salivary gland http://purl.obolibrary.org/obo/CL_0002623 acinar cell of salivary gland An acinar cell of the salivary gland, responsible for producing a viscous, mucin‐rich solution, thereby facilitating lubrication and protection of the oral mucosa. This cell is characterized by an elongated shape, clear cytoplasm filled with mucin granules, and a basally compressed nucleus (Barrows et al., 2020). In humans and mice, the mucous acinar cell predominates in the sublingual gland and minor salivary glands, while also being present in mixed glands such as the submandibular gland, where it coexists with serous acinar cells (Maruyama et al., 2019). http://purl.obolibrary.org/obo/CL_4052067 seromucous acinar cell of salivary gland http://purl.obolibrary.org/obo/CL_0002623 acinar cell of salivary gland An acinar cell of the salivary gland, with a hybrid seromucous phenotype, co-expressing serous and mucous markers and producing a mixed secretion of enzymes-containing serous fluid and mucins essential for lubrication, digestion, and antimicrobial defense. Predominant in the submandibular glands of humans and mice, its differentiation and secretory gene expression are regulated by FGFR2b–MAPK signaling, driven by paracrine FGF7 from adjacent myoepithelial cells, which provides a key niche signal for seromucous identity. http://purl.obolibrary.org/obo/CL_4052069 excretory duct cell of salivary gland http://purl.obolibrary.org/obo/CL_1001596 salivary gland glandular cell A duct epithelial cell that is part of the excretory duct of the salivary gland, which transports saliva from the intralobular ductal system to the oral cavity. While primarily serving as a conduit, this cell may play a role in the saliva modification, contributing to its hypotonicity. In humans, this cell has a pseudostratified columnar shape. http://purl.obolibrary.org/obo/CL_4052070 dual-feature fallopian tube progenitor cell http://purl.obolibrary.org/obo/CL_0011026 progenitor cell A bipotent progenitor cell within the human fallopian tube epithelium, characterized by the concurrent expression of epithelial (e.g., EpCAM/CD326) and endothelial (e.g., PECAM1/CD31) markers at both the cell surface and transcript levels. This cell has the capacity to differentiate into ciliated and secretory epithelial cells, as well as potentially endothelial/stromal lineages. Positioned at the apex of lineage bifurcation, the cell exhibits stem-like and endothelial features, representing an intermediate developmental state between undifferentiated progenitors and lineage-committed epithelial cells. http://purl.obolibrary.org/obo/CL_4052071 quiescent fibroblast http://purl.obolibrary.org/obo/CL_0000057 fibroblast A fibroblast in a quiescent state, characterized by a smaller, spindle-shaped morphology with a relatively small cytoplasm, modest rough endoplasmic reticulum and condensed chromatin. Despite low proliferation and contractility, it maintains high metabolic activity for extracellular-matrix homeostasis through continuous matrix protein turnover and mechanosensitive signaling. This cell can rapidly differentiate into contractile myofibroblasts under injury or inflammatory cues to drive tissue repair. http://purl.obolibrary.org/obo/CL_4072006 A9 dopaminergic neuron http://purl.obolibrary.org/obo/CL_0008060 GABA-Glut neuron A type of dopaminergic neuron in the substantia nigra involved in motor control and particularly vulnerable in Parkinson’s disease. In mice, it is notable for its heterogeneous co-release of dopamine with either glutamate or GABA. It releases GABA through alternative synthesis pathways or reuptake mechanisms independent of GAD expression. http://purl.obolibrary.org/obo/CL_4072014 tanycyte of vascular organ of lamina terminalis http://purl.obolibrary.org/obo/CL_2000030 hypothalamus cell A specialized, non-ciliated ependymal glial cell located in the ventricular wall of the organum vasculosum of the lamina terminalis (OVLT) and characterized by elongated basal processes extending into the parenchyma to contact fenestrated capillaries. In mice, it is characterised by the expression of tight junction proteins (claudin 1, occludin, ZO-1) forming a continuous honeycomb junctional pattern. This cell contributes to a functional blood–cerebrospinal fluid (CSF) barrier at the ventricular interface of the OVLT. http://purl.obolibrary.org/obo/CL_4072015 monocyte-derived Kupffer cell http://purl.obolibrary.org/obo/CL_0000091 Kupffer cell A Kupffer cell located within the hepatic sinusoids, derived from circulating bone marrow monocytes that acquire the phenotypic markers and functional properties of resident Kupffer cells through niche-dependent imprinting, typically following depletion of the embryonically derived Kupffer cell population. During liver injury, MoKCs become the dominant Kupffer cell subset, exhibiting enhanced proliferation, resistance to apoptosis, and key roles in tissue repair and fibrosis attenuation. http://purl.obolibrary.org/obo/CL_4072016 NPY interneuron http://purl.obolibrary.org/obo/CL_0011005 GABAergic interneuron An interneuron that expresses neuropeptide Y (NPY) and is mainly located in cortical layers II–III and VI, as well as in various brain regions such as the medial geniculate and inferior colliculus. The NPY cell population is physiologically diverse, displaying a range of firing behaviors, including adapting, fast-spiking, and accelerating patterns. http://purl.obolibrary.org/obo/CL_4072017 agouti-related protein expressing neuron http://purl.obolibrary.org/obo/CL_0012001 neuron of the forebrain A GABAergic neuron located in the arcuate nucleus of the hypothalamus that expresses agouti-related protein (AgRP). This neuron can coexpress AgRP, GABA, and neuropeptide Y (NPY) in mice, and plays a key role in integrating metabolic signals. It is activated by hunger-related hormones such as ghrelin and inhibited by satiety signals like leptin. http://purl.obolibrary.org/obo/CL_4072018 pacemaker neuron http://purl.obolibrary.org/obo/CL_0000540 neuron A neuron that generates rhythmic bursts of action potentials independently of synaptic input. This intrinsic property enables it to maintain oscillatory activity even when isolated from other neurons. It populates the brainstem, hypothalamus, basal ganglia, spinal cord, and cerebellum. It plays a crucial role in regulating circadian rhythms in the suprachiasmatic nucleus, generating respiratory rhythms in the preBötzinger complex, and synchronizing neural networks. http://purl.obolibrary.org/obo/CL_4072019 SCN pacemaker neuron http://purl.obolibrary.org/obo/CL_0012001 neuron of the forebrain A type of neuron located in the suprachiasmatic nucleus (SCN) that possesses intrinsic circadian rhythmicity, characterized by strong and rhythmic expression of core clock genes and the ability to independently generate and sustain circadian oscillations. In mice, the specific subtypes Avp+/Nms+, Vip+/Nms+, and Cck+/C1ql3+ neurons have the most robust circadian gene expression and contribute to synchronizing and maintaining rhythmicity within the SCN network (Wen et al., 2020). http://purl.obolibrary.org/obo/CL_4072021 corticotropin-releasing neuron http://purl.obolibrary.org/obo/CL_0000467 adrenocorticotropic hormone secreting cell A specialised type of interneuron defined by the secretion of corticotropin-releasing hormone (CRH), a key peptide in activating the hypothalamic–pituitary–adrenal (HPA) axis during stress. It is primarily located in the paraventricular nucleus (PVN) of the hypothalamus, with additional presence in the hippocampus, piriform area, central amygdalar nucleus, Barrington’s nucleus, and inferior olivary complex (Peng et al., 2017). http://purl.obolibrary.org/obo/CL_4072022 Lamp5 Lhx6 GABAergic interneuron (Homo sapiens) http://purl.obolibrary.org/obo/CL_4042013 Lamp5 Lhx6 neuron A Lamp5 Lhx6 GABAergic interneuron of Homo sapiens. The standard transcriptomic reference data for this cell type can be found on the CellxGene census under the collection: 'Transcriptomic cytoarchitecture reveals principles of human neocortex organization', dataset: 'Supercluster: CGE-derived interneurons', Author Categories: 'CrossArea_subclass', Lamp5 Lhx6 http://purl.obolibrary.org/obo/CL_4072027 sst GABAergic interneuron (Homo sapiens) http://purl.obolibrary.org/obo/CL_4023017 sst GABAergic interneuron A transcriptomically distinct GABAergic neuron located in the cerebral cortex that expresses somatostatin (sst). The standard transcriptomic reference data for this cell type can be found on the CellxGene census under the collection: 'Transcriptomic cytoarchitecture reveals principles of human neocortex organization', dataset: 'Supercluster: MGE-derived interneurons', Author Categories: 'CrossArea_subclass', cluster Sst. http://purl.obolibrary.org/obo/CL_4072029 pvalb GABAergic interneuron (Homo sapiens) http://purl.obolibrary.org/obo/CL_4023018 pvalb GABAergic interneuron A transcriptomically distinct GABAergic interneuron with a soma located in a cerebral cortex and it expresses Parvalbumin. The standard transcriptomic reference data for this cell type can be found on the CellxGene census under the collection: 'Transcriptomic cytoarchitecture reveals principles of human neocortex organization', dataset: 'Supercluster: MGE-derived interneurons', Author Categories: 'CrossArea_subclass', cluster Pvalb. http://purl.obolibrary.org/obo/CL_4072031 sst chodl GABAergic interneuron (Homo sapiens) http://purl.obolibrary.org/obo/CL_4023121 sst chodl GABAergic interneuron A transcriptomically distinct sst GABAergic interneuron that also expresses Chodl. These neurons are rare and correspond to the only known interneurons with long-range projection. The standard transcriptomic reference data for this cell type can be found on the CellxGene census under the collection: 'Transcriptomic cytoarchitecture reveals principles of human neocortex organization', dataset: 'Supercluster: MGE-derived interneurons', Author Categories: 'CrossArea_subclass', clusters Sst Chodl. http://purl.obolibrary.org/obo/CL_4072032 VIP GABAergic interneuron (Homo sapiens) http://purl.obolibrary.org/obo/CL_4023016 VIP GABAergic interneuron A transcriptomically distinct GABAergic neuron that expresses the vasoactive intestinal polypeptide and that has its soma located in the forebrain. The standard transcriptomic reference data for this cell type can be found on the CellxGene census under the collection: 'Transcriptomic cytoarchitecture reveals principles of human neocortex organization', dataset: 'Supercluster: CGE-derived interneurons', Author Categories: 'CrossArea_subclass', cluster Vip. http://purl.obolibrary.org/obo/CL_4072034 lamp5 GABAergic interneuron (Homo sapiens) http://purl.obolibrary.org/obo/CL_4023011 lamp5 GABAergic interneuron A transcriptomically distinct GABAergic neuron located in the cerebral cortex that expresses Lamp5. The standard transcriptomic reference data for this cell type can be found on the CellxGene census under the collection: 'Transcriptomic cytoarchitecture reveals principles of human neocortex organization', dataset: 'Supercluster: CGE-derived interneurons', Author Categories: 'CrossArea_subclass', clusters Lamp5. http://purl.obolibrary.org/obo/CL_4072035 sncg GABAergic interneuron (Homo sapiens) http://purl.obolibrary.org/obo/CL_4023015 sncg GABAergic interneuron A transcriptomically distinct GABAergic neuron located in the cerebral cortex that expresses Gamma-synuclein. The standard transcriptomic reference data for this cell type can be found on the CellxGene census under the collection: 'Transcriptomic cytoarchitecture reveals principles of human neocortex organization', dataset: 'Supercluster: CGE-derived interneurons', Author Categories: 'CrossArea_subclass', clusters Sncg. http://purl.obolibrary.org/obo/CL_4072036 PAX6 GABAergic interneuron (Homo sapiens) http://purl.obolibrary.org/obo/CL_4042032 PAX6 GABAergic interneuron A transcriptomically distinct GABAergic neuron located in the cerebral cortex that expresses the transcript PAX6. The standard transcriptomic reference data for this cell type can be found on the CellxGene census under the collection: 'Transcriptomic cytoarchitecture reveals principles of human neocortex organization', dataset: 'Supercluster: CGE-derived interneurons', Author Categories: 'CrossArea_subclass', clusters PAX http://purl.obolibrary.org/obo/CL_4072037 L2/3 intratelencephalic projecting glutamatergic neuron (Homo sapiens) http://purl.obolibrary.org/obo/CL_4030059 L2/3 intratelencephalic projecting glutamatergic neuron A transcriptomically distinct intratelencephalic-projecting glutamatergic neuron with a soma found between cortical layer 2-4. This intratelencephalic-projecting glutamatergic neuron has thin-tufted apical dendrites and extends its axonal projection into L5 in the neocortex. This neuronal type has a hyperpolarised resting membrane potential. The standard transcriptomic reference data for this cell type can be found on the CellxGene census under the collection: 'Transcriptomic cytoarchitecture reveals principles of human neocortex organization', dataset: 'Supercluster: IT-projecting excitatory neurons', Author Categories: 'CrossArea_subclass', clusters L2/3 IT. http://purl.obolibrary.org/obo/CL_4072038 L5 intratelencephalic projecting glutamatergic neuron (Homo sapiens) http://purl.obolibrary.org/obo/CL_4030064 L5 intratelencephalic projecting glutamatergic neuron An intratelencephalic-projecting glutamatergic neuron with a soma found in cortical layer 5. The standard transcriptomic reference data for this cell type can be found on the CellxGene census under the collection: 'Transcriptomic cytoarchitecture reveals principles of human neocortex organization', dataset: 'Supercluster: IT-projecting excitatory neurons', Author Categories: 'CrossArea_subclass', L5 IT. http://purl.obolibrary.org/obo/CL_4072039 L4 intratelencephalic projecting glutamatergic neuron (Homo sapiens) http://purl.obolibrary.org/obo/CL_4030063 L4 intratelencephalic projecting glutamatergic neuron A transcriptomically distinct intratelencephalic-projecting glutamatergic neuron with a soma found in cortical layer 3-4. This neuron type can have a pyramidal, star-pyramidal or spiny stellate morphology and projects its output to L2/3 and L5A/B. The standard transcriptomic reference data for this cell type can be found on the CellxGene census under the collection: 'Transcriptomic cytoarchitecture reveals principles of human neocortex organization', dataset: 'Supercluster: IT-projecting excitatory neurons', Author Categories: 'CrossArea_subclass', L4 IT. http://purl.obolibrary.org/obo/CL_4072040 L6 intratelencephalic projecting Car3 glutamatergic neuron (Homo sapiens) http://purl.obolibrary.org/obo/CL_4030068 L6 intratelencephalic projecting Car3 glutamatergic neuron A transcriptomically distinct intratelencepalic-projecting glutamatergic neuron that expresses Car3 with a soma found in L6. The standard transcriptomic reference data for this cell type can be found on the CellxGene census under the collection: 'Transcriptomic cytoarchitecture reveals principles of human neocortex organization', dataset: 'Supercluster: IT-projecting excitatory neurons', Author Categories: 'CrossArea_cluster', L6 IT Car3. http://purl.obolibrary.org/obo/CL_4072041 L6 intratelencephalic projecting glutamatergic neuron (Homo sapiens) http://purl.obolibrary.org/obo/CL_4030065 L6 intratelencephalic projecting glutamatergic neuron A transcriptomically distinct intratelencephalic-projecting glutamatergic neuron with a soma found in L6 of the primary motor cortex. These cells are short untufted pyramidal cells, which could be stellate or inverted. The standard transcriptomic reference data for this cell type can be found on the CellxGene census under the collection: 'Transcriptomic cytoarchitecture reveals principles of human neocortex organization', dataset: 'Supercluster: IT-projecting excitatory neurons', Author Categories: 'CrossArea_subclass', L6 IT. http://purl.obolibrary.org/obo/CL_4072042 L5/6 near-projecting glutamatergic neuron (Homo sapiens) http://purl.obolibrary.org/obo/CL_4030067 L5/6 near-projecting glutamatergic neuron A transcriptomically defined near-projecting glutamatergic neuron with a soma found in cortical layer 5/6 in humans. http://purl.obolibrary.org/obo/CL_4072043 L5 extratelencephalic projecting glutamatergic cortical neuron (Homo sapiens) http://purl.obolibrary.org/obo/CL_4023041 L5 extratelencephalic projecting glutamatergic cortical neuron A transcriptomically distinct glutamatergic neuron, with a soma found in the deeper portion of L5, that has long-range axonal projections including deep subcortical targets outside of the telencephalon and, in some cases, the spinal cord. While the L5 ET neuron projections are not limited to ET targets, they are clearly differentiated from the neuron subclasses whose projections are constrained to intratelencephalic (IT) targets. L5 ET neurons are generally the largest excitatory cortical neurons, typically having a thick apical dendrite with a prominent dendritic tuft in layer 1 and displaying burst-firing physiological characteristics. The standard transcriptomic reference data for this cell type can be found on the CellxGene census under the collection: 'Transcriptomic cytoarchitecture reveals principles of human neocortex organization', dataset: 'Supercluster: Deep layer (non-IT) excitatory neurons ', Author Categories: 'CrossArea_subclass', clusters L5 ET. http://purl.obolibrary.org/obo/CL_4072044 L6 corticothalamic-projecting glutamatergic cortical neuron (Homo sapiens) http://purl.obolibrary.org/obo/CL_4023042 L6 corticothalamic-projecting glutamatergic cortical neuron A transcriptomically distinct corticothalamic-projecting neuron with a soma found in cortical layer 6. The standard transcriptomic reference data for this cell type can be found on the CellxGene census under the collection: 'Transcriptomic cytoarchitecture reveals principles of human neocortex organization', dataset: 'Supercluster: Deep layer (non-IT) excitatory neurons', Author Categories: 'CrossArea_subclass', clusters L6 CT. http://purl.obolibrary.org/obo/CL_4072045 L6b glutamatergic cortical neuron (Homo sapiens) http://purl.obolibrary.org/obo/CL_4023038 L6b glutamatergic cortical neuron A glutamatergic neuron with a soma found in cortical layer 6b. They are transcriptomically related to corticothalamic-projecting neurons but have differential projections to the thalamus or anterior cingulate. The standard transcriptomic reference data for this cell type can be found on the CellxGene census under the collection: 'Transcriptomic cytoarchitecture reveals principles of human neocortex organization', dataset: 'Supercluster: Deep layer (non-IT) excitatory neuron', Author Categories: 'CrossArea_subclass', cluster L6b. http://purl.obolibrary.org/obo/CL_4072046 pvalb chandelier GABAergic interneuron (Homo sapiens) http://purl.obolibrary.org/obo/CL_4023036 pvalb chandelier GABAergic interneuron A transcriptomically definined GABAergic interneuron of the human pallium. These cells correspond to the classically defined pvalb chandelier neuron type. The standard transcriptomic reference data for this cell type can be found on the CellxGene census under the collection: 'Transcriptomic cytoarchitecture reveals principles of human neocortex organization', dataset: 'Supercluster: CGE-derived interneurons', Author Categories: 'CrossArea_subclass', clusters Chandelier. http://purl.obolibrary.org/obo/CL_7770002 juxtacanalicular tissue cell http://purl.obolibrary.org/obo/CL_0002367 trabecular meshwork cell A trabecular meshwork cell of the juxtacanalicular tissue (JCT), characterized by a spindle-shaped, fibroblast-like morphology within a loose extracellular matrix immediately adjacent to Schlemm's canal. It expresses CHI3L1 (human and mouse) and ANGPTL7 (human), as well as smooth muscle actin for contractility. Unlike other trabecular meshwork cells, it does not form monolayers but exists in a loose network, regulating aqueous humor outflow resistance through continuous ECM remodelling, mechanotransduction, and formation of intracellular pores historically called giant vacuoles. http://purl.obolibrary.org/obo/CL_7770003 beam A cell http://purl.obolibrary.org/obo/CL_7770005 beam cell A beam cell within the eye's trabecular meshwork, molecularly distinguished by FABP4 expression in humans and spatially intermingled with Beam B cells throughout the uveal and corneoscleral meshwork regions. In mice, a transcriptionally analogous Beam A–like cluster (mC14) exists, sharing core TM markers (Myoc, Mgp, Pdpn, Chil1) and functional attributes. http://purl.obolibrary.org/obo/CL_7770005 beam cell http://purl.obolibrary.org/obo/CL_0002367 trabecular meshwork cell A trabecular meshwork cell that is part of the eye's trabecular meshwork, residing in the uveal and corneoscleral meshwork regions and serving as the primary biological filter in the aqueous humor drainage cascade. This cell exhibits endothelial-like properties, including production of antithrombogenic substances such as tissue plasminogen activator, while also demonstrating phagocytic activity to remove cellular debris from aqueous humour before the fluid moves deeper into the less porous juxtacanalicular tissue. http://purl.obolibrary.org/obo/CL_7770006 beam B cell, human http://purl.obolibrary.org/obo/CL_0002367 trabecular meshwork cell A trabecular meshwork cell within the eye's trabecular meshwork. This cell is molecularly distinguished by TMEFF2 expression in humans. A beam B cell is spatially intermingled with beam A cells throughout the uveal and corneoscleral meshwork regions, but demonstrates a tendency to localise closer to the juxtacanalicular tissue. http://purl.obolibrary.org/obo/GO_0008219 cell death http://purl.obolibrary.org/obo/GO_0009987 cellular process Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as apoptotic bodies). The cell corpse (or its fragments) may be engulfed by an adjacent cell in vivo, but engulfment of whole cells should not be considered a strict criteria to define cell death as, under some circumstances, live engulfed cells can be released from phagosomes (see PMID:18045538). http://purl.obolibrary.org/obo/GO_0008277 regulation of G protein-coupled receptor signaling pathway http://purl.obolibrary.org/obo/GO_0009966 regulation of signal transduction Any process that modulates the frequency, rate or extent of G protein-coupled receptor signaling pathway. http://purl.obolibrary.org/obo/GO_0008285 negative regulation of cell population proliferation http://purl.obolibrary.org/obo/GO_0042127 regulation of cell population proliferation Any process that stops, prevents or reduces the rate or extent of cell proliferation. http://purl.obolibrary.org/obo/GO_0008292 acetylcholine biosynthetic process http://purl.obolibrary.org/obo/GO_0009058 biosynthetic process The chemical reactions and pathways resulting in the formation of acetylcholine, the acetic acid ester of the organic base choline. http://purl.obolibrary.org/obo/GO_0008299 isoprenoid biosynthetic process http://purl.obolibrary.org/obo/GO_0008610 lipid biosynthetic process The chemical reactions and pathways resulting in the formation of an isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues. http://purl.obolibrary.org/obo/GO_0008300 isoprenoid catabolic process http://purl.obolibrary.org/obo/GO_0016042 lipid catabolic process The chemical reactions and pathways resulting in the breakdown of an isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues. http://purl.obolibrary.org/obo/GO_0008320 protein transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0140318 protein transporter activity Enables the transfer of a protein from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0008328 ionotropic glutamate receptor complex http://purl.obolibrary.org/obo/GO_0098878 neurotransmitter receptor complex A multimeric assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand-gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex. http://purl.obolibrary.org/obo/GO_0008347 glial cell migration http://purl.obolibrary.org/obo/GO_0016477 cell migration The orderly movement of a glial cell, non-neuronal cells that provide support and nutrition, maintain homeostasis, form myelin, and participate in signal transmission in the nervous system. http://purl.obolibrary.org/obo/GO_0008355 olfactory learning http://purl.obolibrary.org/obo/GO_0042048 olfactory behavior Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs in response to (repeated) exposure to an olfactory cue. http://purl.obolibrary.org/obo/GO_0008366 axon ensheathment http://purl.obolibrary.org/obo/GO_0007272 ensheathment of neurons Any process in which the axon of a neuron is insulated, and that insulation maintained, thereby preventing dispersion of the electrical signal. http://purl.obolibrary.org/obo/GO_0008502 melatonin receptor activity http://purl.obolibrary.org/obo/GO_0004930 G protein-coupled receptor activity Combining with melatonin, N-acetyl-5-methoxytryptamine, to initiate a change in cell activity. Melatonin is a neuroendocrine substance that stimulates the aggregation of melanosomes in melanophores, thus lightening the skin. http://purl.obolibrary.org/obo/GO_0008544 epidermis development http://purl.obolibrary.org/obo/GO_0009888 tissue development The process whose specific outcome is the progression of the epidermis over time, from its formation to the mature structure. The epidermis is the outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species. http://purl.obolibrary.org/obo/GO_0008584 male gonad development http://purl.obolibrary.org/obo/GO_0008406 gonad development The process whose specific outcome is the progression of the male gonad over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0008594 photoreceptor cell morphogenesis http://purl.obolibrary.org/obo/GO_0048667 cell morphogenesis involved in neuron differentiation The process in which the structures of a photoreceptor cell are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a photoreceptor cell, a sensory cell that reacts to the presence of light. An example of this is found in Drosophila melanogaster. http://purl.obolibrary.org/obo/GO_0008645 hexose transmembrane transport http://purl.obolibrary.org/obo/GO_0015749 monosaccharide transmembrane transport The process in which hexose is transported across a membrane. Hexoses are aldoses with a chain of six carbon atoms in the molecule. http://purl.obolibrary.org/obo/GO_0009056 catabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process A cellular process consisting of the biochemical pathways by which a living organism breaks down substances. This includes the breakdown of carbon compounds with the liberation of energy for use by the cell or organism. http://purl.obolibrary.org/obo/GO_0009133 nucleoside diphosphate biosynthetic process http://purl.obolibrary.org/obo/GO_1901293 nucleoside phosphate biosynthetic process The chemical reactions and pathways resulting in the formation of a nucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with diphosphate on the sugar. http://purl.obolibrary.org/obo/GO_0009134 nucleoside diphosphate catabolic process http://purl.obolibrary.org/obo/GO_1901292 nucleoside phosphate catabolic process The chemical reactions and pathways resulting in the breakdown of a nucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with diphosphate on the sugar. http://purl.obolibrary.org/obo/GO_0009135 purine nucleoside diphosphate metabolic process http://purl.obolibrary.org/obo/GO_0009132 nucleoside diphosphate metabolic process The chemical reactions and pathways involving purine nucleoside diphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar. http://purl.obolibrary.org/obo/GO_0009136 purine nucleoside diphosphate biosynthetic process http://purl.obolibrary.org/obo/GO_0009135 purine nucleoside diphosphate metabolic process The chemical reactions and pathways resulting in the formation of purine nucleoside diphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar. http://purl.obolibrary.org/obo/GO_0009137 purine nucleoside diphosphate catabolic process http://purl.obolibrary.org/obo/GO_0009135 purine nucleoside diphosphate metabolic process The chemical reactions and pathways resulting in the breakdown of purine nucleoside diphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar. http://purl.obolibrary.org/obo/GO_0009141 nucleoside triphosphate metabolic process http://purl.obolibrary.org/obo/GO_0006753 nucleoside phosphate metabolic process The chemical reactions and pathways involving a nucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with triphosphate on the sugar. http://purl.obolibrary.org/obo/GO_0009142 nucleoside triphosphate biosynthetic process http://purl.obolibrary.org/obo/GO_1901293 nucleoside phosphate biosynthetic process The chemical reactions and pathways resulting in the formation of a nucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with triphosphate on the sugar. http://purl.obolibrary.org/obo/GO_0009143 nucleoside triphosphate catabolic process http://purl.obolibrary.org/obo/GO_1901292 nucleoside phosphate catabolic process The chemical reactions and pathways resulting in the breakdown of a nucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with triphosphate on the sugar. http://purl.obolibrary.org/obo/GO_0009144 purine nucleoside triphosphate metabolic process http://purl.obolibrary.org/obo/GO_0009141 nucleoside triphosphate metabolic process The chemical reactions and pathways involving purine nucleoside triphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar. http://purl.obolibrary.org/obo/GO_0009145 purine nucleoside triphosphate biosynthetic process http://purl.obolibrary.org/obo/GO_0009144 purine nucleoside triphosphate metabolic process The chemical reactions and pathways resulting in the formation of purine nucleoside triphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar. http://purl.obolibrary.org/obo/GO_0009146 purine nucleoside triphosphate catabolic process http://purl.obolibrary.org/obo/GO_0009144 purine nucleoside triphosphate metabolic process The chemical reactions and pathways resulting in the breakdown of purine nucleoside triphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar. http://purl.obolibrary.org/obo/GO_0009150 purine ribonucleotide metabolic process http://purl.obolibrary.org/obo/GO_0009259 ribonucleotide metabolic process The chemical reactions and pathways involving a purine ribonucleotide, a compound consisting of ribonucleoside (a purine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. http://purl.obolibrary.org/obo/GO_0009179 purine ribonucleoside diphosphate metabolic process http://purl.obolibrary.org/obo/GO_0009185 ribonucleoside diphosphate metabolic process The chemical reactions and pathways involving purine ribonucleoside diphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with diphosphate on the sugar. http://purl.obolibrary.org/obo/GO_0009181 purine ribonucleoside diphosphate catabolic process http://purl.obolibrary.org/obo/GO_0009191 ribonucleoside diphosphate catabolic process The chemical reactions and pathways resulting in the breakdown of purine ribonucleoside diphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with diphosphate on the sugar. http://purl.obolibrary.org/obo/GO_0009185 ribonucleoside diphosphate metabolic process http://purl.obolibrary.org/obo/GO_0009132 nucleoside diphosphate metabolic process The chemical reactions and pathways involving a ribonucleoside diphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with diphosphate on the sugar. http://purl.obolibrary.org/obo/GO_0009188 ribonucleoside diphosphate biosynthetic process http://purl.obolibrary.org/obo/GO_0009185 ribonucleoside diphosphate metabolic process The chemical reactions and pathways resulting in the formation of a ribonucleoside diphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with diphosphate on the sugar. http://purl.obolibrary.org/obo/GO_0009191 ribonucleoside diphosphate catabolic process http://purl.obolibrary.org/obo/GO_0009185 ribonucleoside diphosphate metabolic process The chemical reactions and pathways resulting in the breakdown of a ribonucleoside diphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with diphosphate on the sugar. http://purl.obolibrary.org/obo/GO_0009201 ribonucleoside triphosphate biosynthetic process http://purl.obolibrary.org/obo/GO_0009142 nucleoside triphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of a ribonucleoside triphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with triphosphate on the sugar. http://purl.obolibrary.org/obo/GO_0009203 ribonucleoside triphosphate catabolic process http://purl.obolibrary.org/obo/GO_0009143 nucleoside triphosphate catabolic process The chemical reactions and pathways resulting in the breakdown of a ribonucleoside triphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with triphosphate on the sugar. http://purl.obolibrary.org/obo/GO_0009205 purine ribonucleoside triphosphate metabolic process http://purl.obolibrary.org/obo/GO_0009144 purine nucleoside triphosphate metabolic process The chemical reactions and pathways involving purine ribonucleoside triphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with triphosphate on the sugar. http://purl.obolibrary.org/obo/GO_0009259 ribonucleotide metabolic process http://purl.obolibrary.org/obo/GO_0019693 ribose phosphate metabolic process The chemical reactions and pathways involving a ribonucleotide, a compound consisting of ribonucleoside (a base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. http://purl.obolibrary.org/obo/GO_0009260 ribonucleotide biosynthetic process http://purl.obolibrary.org/obo/GO_0009259 ribonucleotide metabolic process The chemical reactions and pathways resulting in the formation of a ribonucleotide, a compound consisting of ribonucleoside (a base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. http://purl.obolibrary.org/obo/GO_0009261 ribonucleotide catabolic process http://purl.obolibrary.org/obo/GO_0009259 ribonucleotide metabolic process The chemical reactions and pathways resulting in the breakdown of a ribonucleotide, a compound consisting of ribonucleoside (a base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. http://purl.obolibrary.org/obo/GO_0009266 response to temperature stimulus http://purl.obolibrary.org/obo/GO_0009628 response to abiotic stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temperature stimulus. http://purl.obolibrary.org/obo/GO_0009295 nucleoid http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure The region of a virus, bacterial cell, mitochondrion or chloroplast to which the nucleic acid is confined. http://purl.obolibrary.org/obo/GO_0009308 amine metabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process The chemical reactions and pathways involving any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom. http://purl.obolibrary.org/obo/GO_0009309 amine biosynthetic process http://purl.obolibrary.org/obo/GO_0009308 amine metabolic process The chemical reactions and pathways resulting in the formation of any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom. http://purl.obolibrary.org/obo/GO_0009310 amine catabolic process http://purl.obolibrary.org/obo/GO_0009308 amine metabolic process The chemical reactions and pathways resulting in the breakdown of any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom. http://purl.obolibrary.org/obo/GO_0009314 response to radiation http://purl.obolibrary.org/obo/GO_0009628 response to abiotic stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation. http://purl.obolibrary.org/obo/GO_0009399 nitrogen fixation http://purl.obolibrary.org/obo/GO_0071941 nitrogen cycle metabolic process The process in which nitrogen is taken from its relatively inert molecular form (N2) in the atmosphere and converted into ammonium, which is more biologically available. http://purl.obolibrary.org/obo/GO_0009411 response to UV http://purl.obolibrary.org/obo/GO_0009416 response to light stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultraviolet radiation (UV light) stimulus. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers. http://purl.obolibrary.org/obo/GO_0009414 response to water deprivation http://purl.obolibrary.org/obo/GO_0009415 response to water Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water deprivation stimulus, prolonged deprivation of water. http://purl.obolibrary.org/obo/GO_0009415 response to water http://purl.obolibrary.org/obo/GO_1901700 response to oxygen-containing compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of water. http://purl.obolibrary.org/obo/GO_0009448 gamma-aminobutyric acid metabolic process http://purl.obolibrary.org/obo/GO_0170041 non-proteinogenic amino acid metabolic process The chemical reactions and pathways involving gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms. http://purl.obolibrary.org/obo/GO_0009449 gamma-aminobutyric acid biosynthetic process http://purl.obolibrary.org/obo/GO_0170043 non-proteinogenic amino acid biosynthetic process The chemical reactions and pathways resulting in the formation of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms. http://purl.obolibrary.org/obo/GO_0009450 gamma-aminobutyric acid catabolic process http://purl.obolibrary.org/obo/GO_0170044 non-proteinogenic amino acid catabolic process The chemical reactions and pathways resulting in the breakdown of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms. http://purl.obolibrary.org/obo/GO_0009507 chloroplast http://purl.obolibrary.org/obo/GO_0009536 plastid A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma. http://purl.obolibrary.org/obo/GO_0009508 plastid chromosome http://purl.obolibrary.org/obo/GO_0005694 chromosome A circular DNA molecule containing plastid encoded genes. http://purl.obolibrary.org/obo/GO_0009526 plastid envelope http://purl.obolibrary.org/obo/GO_0031967 organelle envelope The double lipid bilayer enclosing a plastid and separating its contents from the rest of the cytoplasm; includes the intermembrane space. http://purl.obolibrary.org/obo/GO_0009527 plastid outer membrane http://purl.obolibrary.org/obo/GO_0042170 plastid membrane The outer, i.e. cytoplasm-facing, lipid bilayer of the plastid envelope. http://purl.obolibrary.org/obo/GO_0009532 plastid stroma http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure The proteinaceous ground substance of plastids. http://purl.obolibrary.org/obo/GO_0009570 chloroplast stroma http://purl.obolibrary.org/obo/GO_0009532 plastid stroma The space enclosed by the double membrane of a chloroplast but excluding the thylakoid space. It contains DNA, ribosomes and some temporary products of photosynthesis. http://purl.obolibrary.org/obo/GO_0009581 detection of external stimulus http://purl.obolibrary.org/obo/GO_0051606 detection of stimulus The series of events in which an external stimulus is received by a cell and converted into a molecular signal. http://purl.obolibrary.org/obo/GO_0009582 detection of abiotic stimulus http://purl.obolibrary.org/obo/GO_0051606 detection of stimulus The series of events in which an (non-living) abiotic stimulus is received by a cell and converted into a molecular signal. http://purl.obolibrary.org/obo/GO_0009636 response to toxic substance http://purl.obolibrary.org/obo/GO_0042221 response to chemical Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus. http://purl.obolibrary.org/obo/GO_0009657 plastid organization http://purl.obolibrary.org/obo/GO_0006996 organelle organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a plastid. http://purl.obolibrary.org/obo/GO_0009658 chloroplast organization http://purl.obolibrary.org/obo/GO_0009657 plastid organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the chloroplast. http://purl.obolibrary.org/obo/GO_0009665 plastid inheritance http://purl.obolibrary.org/obo/GO_0009657 plastid organization The partitioning of plastids between daughter cells at cell division. http://purl.obolibrary.org/obo/GO_0009666 plastid outer membrane organization http://purl.obolibrary.org/obo/GO_0009668 plastid membrane organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the outer membrane of a plastid. http://purl.obolibrary.org/obo/GO_0009668 plastid membrane organization http://purl.obolibrary.org/obo/GO_0061024 membrane organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of either of the lipid bilayers surrounding a plastid. http://purl.obolibrary.org/obo/GO_0009707 chloroplast outer membrane http://purl.obolibrary.org/obo/GO_0031969 chloroplast membrane The outer, i.e. cytoplasm-facing, lipid bilayer of the chloroplast envelope. http://purl.obolibrary.org/obo/GO_0009713 catechol-containing compound biosynthetic process http://purl.obolibrary.org/obo/GO_0046189 phenol-containing compound biosynthetic process The chemical reactions and pathways resulting in the formation of catechol-containing compounds. Catechol is a compound containing a pyrocatechol nucleus or substituent. http://purl.obolibrary.org/obo/GO_0009719 response to endogenous stimulus http://purl.obolibrary.org/obo/GO_0050896 response to stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus arising within the organism. http://purl.obolibrary.org/obo/GO_0009725 response to hormone http://purl.obolibrary.org/obo/GO_0009719 response to endogenous stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus. http://purl.obolibrary.org/obo/GO_0009743 response to carbohydrate http://purl.obolibrary.org/obo/GO_1901700 response to oxygen-containing compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbohydrate stimulus. http://purl.obolibrary.org/obo/GO_0009746 response to hexose http://purl.obolibrary.org/obo/GO_0034284 response to monosaccharide Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hexose stimulus. http://purl.obolibrary.org/obo/GO_0009749 response to glucose http://purl.obolibrary.org/obo/GO_0009746 response to hexose Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus. http://purl.obolibrary.org/obo/GO_0009786 regulation of asymmetric cell division http://purl.obolibrary.org/obo/GO_0051302 regulation of cell division Any process that modulates the frequency, rate or extent of asymmetric cell division. http://purl.obolibrary.org/obo/GO_0009790 embryo development http://purl.obolibrary.org/obo/GO_0007275 multicellular organism development The process whose specific outcome is the progression of an embryo from its formation until the end of its embryonic life stage. The end of the embryonic stage is organism-specific. For example, for mammals, the process would begin with zygote formation and end with birth. For insects, the process would begin at zygote formation and end with larval hatching. For plant zygotic embryos, this would be from zygote formation to the end of seed dormancy. For plant vegetative embryos, this would be from the initial determination of the cell or group of cells to form an embryo until the point when the embryo becomes independent of the parent plant. http://purl.obolibrary.org/obo/GO_0009889 regulation of biosynthetic process http://purl.obolibrary.org/obo/GO_0019222 regulation of metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances. http://purl.obolibrary.org/obo/GO_0009890 negative regulation of biosynthetic process http://purl.obolibrary.org/obo/GO_0009892 negative regulation of metabolic process Any process that stops, prevents, or reduces the rate of the chemical reactions and pathways resulting in the formation of substances. http://purl.obolibrary.org/obo/GO_0009891 positive regulation of biosynthetic process http://purl.obolibrary.org/obo/GO_0009893 positive regulation of metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances. http://purl.obolibrary.org/obo/GO_0009892 negative regulation of metabolic process http://purl.obolibrary.org/obo/GO_0019222 regulation of metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism. http://purl.obolibrary.org/obo/GO_0009893 positive regulation of metabolic process http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism. http://purl.obolibrary.org/obo/GO_0009894 regulation of catabolic process http://purl.obolibrary.org/obo/GO_0019222 regulation of metabolic process Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of substances. http://purl.obolibrary.org/obo/GO_0009895 negative regulation of catabolic process http://purl.obolibrary.org/obo/GO_0009894 regulation of catabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances. http://purl.obolibrary.org/obo/GO_0009896 positive regulation of catabolic process http://purl.obolibrary.org/obo/GO_0009894 regulation of catabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances. http://purl.obolibrary.org/obo/GO_0009902 chloroplast relocation http://purl.obolibrary.org/obo/GO_0051667 establishment of plastid localization The process in which chloroplasts in photosynthetic cells migrate toward illuminated sites to optimize photosynthesis and move away from excessively illuminated areas to protect the photosynthetic machinery. http://purl.obolibrary.org/obo/GO_0009941 chloroplast envelope http://purl.obolibrary.org/obo/GO_0009526 plastid envelope The double lipid bilayer enclosing the chloroplast and separating its contents from the rest of the cytoplasm; includes the intermembrane space. http://purl.obolibrary.org/obo/GO_0009977 proton motive force dependent protein transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0008320 protein transmembrane transporter activity Catalysis of the transfer of proteins from one side of a membrane to the other. Transportation is dependent on pH gradient across the membrane. http://purl.obolibrary.org/obo/GO_0009992 intracellular water homeostasis http://purl.obolibrary.org/obo/GO_0055082 intracellular chemical homeostasis A homeostatic process involved in the maintenance of a steady state level of water within a cell. http://purl.obolibrary.org/obo/GO_0009994 oocyte differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized immature germ cell acquires the specialized features of a mature female gamete. http://purl.obolibrary.org/obo/GO_0010020 chloroplast fission http://purl.obolibrary.org/obo/GO_0043572 plastid fission The division of a chloroplast within a cell to form two or more separate chloroplast compartments. This division occurs independently of mitosis. http://purl.obolibrary.org/obo/GO_0010032 meiotic chromosome condensation http://purl.obolibrary.org/obo/GO_0030261 chromosome condensation Compaction of chromatin structure prior to meiosis in eukaryotic cells. http://purl.obolibrary.org/obo/GO_0010038 response to metal ion http://purl.obolibrary.org/obo/GO_0042221 response to chemical Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metal ion stimulus. http://purl.obolibrary.org/obo/GO_0010039 response to iron ion http://purl.obolibrary.org/obo/GO_0010038 response to metal ion Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron ion stimulus. http://purl.obolibrary.org/obo/GO_0010070 zygote asymmetric cell division http://purl.obolibrary.org/obo/GO_0008356 asymmetric cell division The division of the zygote into two daughter cells that will adopt developmentally distinct potentials. http://purl.obolibrary.org/obo/GO_0010109 regulation of photosynthesis http://purl.obolibrary.org/obo/GO_0019222 regulation of metabolic process Any process that modulates the frequency, rate or extent of photosynthesis. http://purl.obolibrary.org/obo/GO_0010155 regulation of proton transport http://purl.obolibrary.org/obo/GO_1904062 regulation of monoatomic cation transmembrane transport Any process that modulates the frequency, rate or extent of proton transport into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0010171 body morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structures of the soma are generated and organized. http://purl.obolibrary.org/obo/GO_0010232 vascular transport http://purl.obolibrary.org/obo/GO_0003018 vascular process in circulatory system The directed movement of substances, into, out of or within a cell, either in a vascular tissue or in the vascular membrane. http://purl.obolibrary.org/obo/GO_0010453 regulation of cell fate commitment http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field. http://purl.obolibrary.org/obo/GO_0010454 negative regulation of cell fate commitment http://purl.obolibrary.org/obo/GO_0010453 regulation of cell fate commitment Any process that stops, prevents or reduces the frequency or rate of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field. http://purl.obolibrary.org/obo/GO_0010455 positive regulation of cell fate commitment http://purl.obolibrary.org/obo/GO_0045597 positive regulation of cell differentiation Any process that activates, maintains or increases the frequency or rate of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field. http://purl.obolibrary.org/obo/GO_0010456 cell proliferation in dorsal spinal cord http://purl.obolibrary.org/obo/GO_0061351 neural precursor cell proliferation The multiplication or reproduction of cells, resulting in the expansion of the dorsal spinal cord cell population. http://purl.obolibrary.org/obo/GO_0010470 regulation of gastrulation http://purl.obolibrary.org/obo/GO_0045995 regulation of embryonic development Any process that modulates the rate or extent of gastrulation. Gastrulation is the complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals. http://purl.obolibrary.org/obo/GO_0010481 epidermal cell division http://purl.obolibrary.org/obo/GO_0051301 cell division Any process resulting in the physical partitioning and separation of an epidermal cell, any of the cells making up the epidermis, into daughter cells. http://purl.obolibrary.org/obo/GO_0010482 regulation of epidermal cell division http://purl.obolibrary.org/obo/GO_0051302 regulation of cell division Any process that modulates the frequency, rate or extent of the physical partitioning and separation of an epidermal cell into daughter cells. An epidermal cell is any of the cells that make up the epidermis. http://purl.obolibrary.org/obo/GO_0010496 intercellular transport http://purl.obolibrary.org/obo/GO_0009987 cellular process The movement of substances between cells. http://purl.obolibrary.org/obo/GO_0010543 regulation of platelet activation http://purl.obolibrary.org/obo/GO_0050865 regulation of cell activation Any process that modulates the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. http://purl.obolibrary.org/obo/GO_0010544 negative regulation of platelet activation http://purl.obolibrary.org/obo/GO_0030195 negative regulation of blood coagulation Any process that decreases the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. http://purl.obolibrary.org/obo/GO_0010549 regulation of membrane disassembly http://purl.obolibrary.org/obo/GO_0051128 regulation of cellular component organization Any process that modulates the frequency, rate or extent of membrane disassembly. http://purl.obolibrary.org/obo/GO_0010559 regulation of glycoprotein biosynthetic process http://purl.obolibrary.org/obo/GO_1903018 regulation of glycoprotein metabolic process Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide. http://purl.obolibrary.org/obo/GO_0010560 positive regulation of glycoprotein biosynthetic process http://purl.obolibrary.org/obo/GO_1903020 positive regulation of glycoprotein metabolic process Any process that increases the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide. http://purl.obolibrary.org/obo/GO_0010561 negative regulation of glycoprotein biosynthetic process http://purl.obolibrary.org/obo/GO_1903019 negative regulation of glycoprotein metabolic process Any process that decreases the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide. http://purl.obolibrary.org/obo/GO_0010562 positive regulation of phosphorus metabolic process http://purl.obolibrary.org/obo/GO_0051174 regulation of phosphorus metabolic process Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus. http://purl.obolibrary.org/obo/GO_0010563 negative regulation of phosphorus metabolic process http://purl.obolibrary.org/obo/GO_0051174 regulation of phosphorus metabolic process Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus. http://purl.obolibrary.org/obo/GO_0010567 regulation of ketone catabolic process http://purl.obolibrary.org/obo/GO_0009894 regulation of catabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a ketone, carried out by individual cells. http://purl.obolibrary.org/obo/GO_0010572 positive regulation of platelet activation http://purl.obolibrary.org/obo/GO_0010543 regulation of platelet activation Any process that increases the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. http://purl.obolibrary.org/obo/GO_0010581 regulation of starch biosynthetic process http://purl.obolibrary.org/obo/GO_2000904 regulation of starch metabolic process An process which modulate the frequency, rate or extent of starch biosynthesis, the chemical reactions and pathways resulting in the formation of starch. http://purl.obolibrary.org/obo/GO_0010594 regulation of endothelial cell migration http://purl.obolibrary.org/obo/GO_0030334 regulation of cell migration Any process that modulates the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium. http://purl.obolibrary.org/obo/GO_0010595 positive regulation of endothelial cell migration http://purl.obolibrary.org/obo/GO_0010594 regulation of endothelial cell migration Any process that increases the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium. http://purl.obolibrary.org/obo/GO_0010596 negative regulation of endothelial cell migration http://purl.obolibrary.org/obo/GO_0010594 regulation of endothelial cell migration Any process that decreases the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium. http://purl.obolibrary.org/obo/GO_0010611 regulation of cardiac muscle hypertrophy http://purl.obolibrary.org/obo/GO_0043502 regulation of muscle adaptation Any process that modulates the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division. http://purl.obolibrary.org/obo/GO_0010612 regulation of cardiac muscle adaptation http://purl.obolibrary.org/obo/GO_0043502 regulation of muscle adaptation Any process that modulates the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. http://purl.obolibrary.org/obo/GO_0010613 positive regulation of cardiac muscle hypertrophy http://purl.obolibrary.org/obo/GO_0014742 positive regulation of muscle hypertrophy Any process that increases the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division. http://purl.obolibrary.org/obo/GO_0010614 negative regulation of cardiac muscle hypertrophy http://purl.obolibrary.org/obo/GO_0014741 negative regulation of muscle hypertrophy Any process that decreases the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division. http://purl.obolibrary.org/obo/GO_0010615 positive regulation of cardiac muscle adaptation http://purl.obolibrary.org/obo/GO_0014744 positive regulation of muscle adaptation Any process that increases the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. http://purl.obolibrary.org/obo/GO_0010616 negative regulation of cardiac muscle adaptation http://purl.obolibrary.org/obo/GO_0014745 negative regulation of muscle adaptation Any process that decreases the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. http://purl.obolibrary.org/obo/GO_0010623 programmed cell death involved in cell development http://purl.obolibrary.org/obo/GO_0048869 cellular developmental process The activation of endogenous cellular processes that result in the death of a cell as part of its development. http://purl.obolibrary.org/obo/GO_0010624 regulation of Schwann cell proliferation http://purl.obolibrary.org/obo/GO_0060251 regulation of glial cell proliferation Any process that modulates the frequency or rate of multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system. http://purl.obolibrary.org/obo/GO_0010625 positive regulation of Schwann cell proliferation http://purl.obolibrary.org/obo/GO_0060252 positive regulation of glial cell proliferation Any process that increases the frequency or rate of the multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system. http://purl.obolibrary.org/obo/GO_0010626 negative regulation of Schwann cell proliferation http://purl.obolibrary.org/obo/GO_0060253 negative regulation of glial cell proliferation Any process that decreases the frequency or extent of the multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system. http://purl.obolibrary.org/obo/GO_0010628 positive regulation of gene expression http://purl.obolibrary.org/obo/GO_0010557 positive regulation of macromolecule biosynthetic process Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA). http://purl.obolibrary.org/obo/GO_0010632 regulation of epithelial cell migration http://purl.obolibrary.org/obo/GO_0051239 regulation of multicellular organismal process Any process that modulates the frequency, rate or extent of epithelial cell migration. http://purl.obolibrary.org/obo/GO_0010633 negative regulation of epithelial cell migration http://purl.obolibrary.org/obo/GO_0010632 regulation of epithelial cell migration Any process that stops, prevents, or reduces the frequency, rate or extent of epithelial cell migration. http://purl.obolibrary.org/obo/GO_0010634 positive regulation of epithelial cell migration http://purl.obolibrary.org/obo/GO_0010632 regulation of epithelial cell migration Any process that activates or increases the frequency, rate or extent of epithelial cell migration. http://purl.obolibrary.org/obo/GO_0010635 regulation of mitochondrial fusion http://purl.obolibrary.org/obo/GO_0010821 regulation of mitochondrion organization Any process that modulates the frequency, rate or extent of merging of two or more mitochondria within a cell to form a single compartment. http://purl.obolibrary.org/obo/GO_0010636 positive regulation of mitochondrial fusion http://purl.obolibrary.org/obo/GO_0010638 positive regulation of organelle organization Any process that increases the frequency, rate or extent of merging of two or more mitochondria within a cell to form a single compartment. http://purl.obolibrary.org/obo/GO_0010637 negative regulation of mitochondrial fusion http://purl.obolibrary.org/obo/GO_0010639 negative regulation of organelle organization Any process that decreases the frequency, rate or extent of merging of two or more mitochondria within a cell to form a single compartment. http://purl.obolibrary.org/obo/GO_0010638 positive regulation of organelle organization http://purl.obolibrary.org/obo/GO_0051130 positive regulation of cellular component organization Any process that increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle. http://purl.obolibrary.org/obo/GO_0010639 negative regulation of organelle organization http://purl.obolibrary.org/obo/GO_0051129 negative regulation of cellular component organization Any process that decreases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle. http://purl.obolibrary.org/obo/GO_0010647 positive regulation of cell communication http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that increases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. http://purl.obolibrary.org/obo/GO_0010648 negative regulation of cell communication http://purl.obolibrary.org/obo/GO_0010646 regulation of cell communication Any process that decreases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. http://purl.obolibrary.org/obo/GO_0010656 negative regulation of muscle cell apoptotic process http://purl.obolibrary.org/obo/GO_0010660 regulation of muscle cell apoptotic process Any process that decreases the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death. http://purl.obolibrary.org/obo/GO_0010657 muscle cell apoptotic process http://purl.obolibrary.org/obo/GO_0006915 apoptotic process A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a muscle cell and result in its death. A muscle cell is a mature contractile cell, commonly known as a myocyte, that forms one of three kinds of muscle. http://purl.obolibrary.org/obo/GO_0010658 striated muscle cell apoptotic process http://purl.obolibrary.org/obo/GO_0010657 muscle cell apoptotic process A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a striated muscle cell and result in its death. Striated muscle cells make up striated muscle fibers which are divided by transverse bands into striations. http://purl.obolibrary.org/obo/GO_0010659 cardiac muscle cell apoptotic process http://purl.obolibrary.org/obo/GO_0010658 striated muscle cell apoptotic process A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a cardiac muscle cell and result in its death. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. http://purl.obolibrary.org/obo/GO_0010660 regulation of muscle cell apoptotic process http://purl.obolibrary.org/obo/GO_0042981 regulation of apoptotic process Any process that modulates the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death. http://purl.obolibrary.org/obo/GO_0010661 positive regulation of muscle cell apoptotic process http://purl.obolibrary.org/obo/GO_0043065 positive regulation of apoptotic process Any process that increases the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death. http://purl.obolibrary.org/obo/GO_0010662 regulation of striated muscle cell apoptotic process http://purl.obolibrary.org/obo/GO_0010660 regulation of muscle cell apoptotic process Any process that modulates the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death. http://purl.obolibrary.org/obo/GO_0010663 positive regulation of striated muscle cell apoptotic process http://purl.obolibrary.org/obo/GO_0010662 regulation of striated muscle cell apoptotic process Any process that increases the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death. http://purl.obolibrary.org/obo/GO_0010664 negative regulation of striated muscle cell apoptotic process http://purl.obolibrary.org/obo/GO_0010662 regulation of striated muscle cell apoptotic process Any process that decreases the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death. http://purl.obolibrary.org/obo/GO_0010665 regulation of cardiac muscle cell apoptotic process http://purl.obolibrary.org/obo/GO_0010662 regulation of striated muscle cell apoptotic process Any process that modulates the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death. http://purl.obolibrary.org/obo/GO_0010666 positive regulation of cardiac muscle cell apoptotic process http://purl.obolibrary.org/obo/GO_0010665 regulation of cardiac muscle cell apoptotic process Any process that increases the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death. http://purl.obolibrary.org/obo/GO_0010667 negative regulation of cardiac muscle cell apoptotic process http://purl.obolibrary.org/obo/GO_0010665 regulation of cardiac muscle cell apoptotic process Any process that decreases the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death. http://purl.obolibrary.org/obo/GO_0010700 negative regulation of norepinephrine secretion http://purl.obolibrary.org/obo/GO_0033604 negative regulation of catecholamine secretion Any process that decreases the frequency, rate or extent of the regulated release of norepinephrine. http://purl.obolibrary.org/obo/GO_0010701 positive regulation of norepinephrine secretion http://purl.obolibrary.org/obo/GO_0033605 positive regulation of catecholamine secretion Any process that increases the frequency, rate or extent of the regulated release of norepinephrine. http://purl.obolibrary.org/obo/GO_0010710 regulation of collagen catabolic process http://purl.obolibrary.org/obo/GO_0010712 regulation of collagen metabolic process Any process that modulates the rate, frequency or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix. http://purl.obolibrary.org/obo/GO_0010711 negative regulation of collagen catabolic process http://purl.obolibrary.org/obo/GO_0010713 negative regulation of collagen metabolic process Any process that decreases the rate, frequency or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix. http://purl.obolibrary.org/obo/GO_0010712 regulation of collagen metabolic process http://purl.obolibrary.org/obo/GO_0019222 regulation of metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. http://purl.obolibrary.org/obo/GO_0010713 negative regulation of collagen metabolic process http://purl.obolibrary.org/obo/GO_0010712 regulation of collagen metabolic process Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. http://purl.obolibrary.org/obo/GO_0010714 positive regulation of collagen metabolic process http://purl.obolibrary.org/obo/GO_0010712 regulation of collagen metabolic process Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. http://purl.obolibrary.org/obo/GO_0010715 regulation of extracellular matrix disassembly http://purl.obolibrary.org/obo/GO_1903053 regulation of extracellular matrix organization Any process that modulates the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix. http://purl.obolibrary.org/obo/GO_0010716 negative regulation of extracellular matrix disassembly http://purl.obolibrary.org/obo/GO_0010715 regulation of extracellular matrix disassembly Any process that decreases the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix. http://purl.obolibrary.org/obo/GO_0010717 regulation of epithelial to mesenchymal transition http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. http://purl.obolibrary.org/obo/GO_0010718 positive regulation of epithelial to mesenchymal transition http://purl.obolibrary.org/obo/GO_0045597 positive regulation of cell differentiation Any process that increases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition is where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. http://purl.obolibrary.org/obo/GO_0010719 negative regulation of epithelial to mesenchymal transition http://purl.obolibrary.org/obo/GO_0010717 regulation of epithelial to mesenchymal transition Any process that decreases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. http://purl.obolibrary.org/obo/GO_0010720 positive regulation of cell development http://purl.obolibrary.org/obo/GO_0060284 regulation of cell development Any process that increases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. http://purl.obolibrary.org/obo/GO_0010721 negative regulation of cell development http://purl.obolibrary.org/obo/GO_0060284 regulation of cell development Any process that decreases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. http://purl.obolibrary.org/obo/GO_0010725 regulation of primitive erythrocyte differentiation http://purl.obolibrary.org/obo/GO_0045646 regulation of erythrocyte differentiation Any process that modulates the rate, frequency, or extent of primitive erythrocyte differentiation. Primitive erythrocyte differentiation occurs as part of the process of primitive hemopoiesis. http://purl.obolibrary.org/obo/GO_0010742 macrophage derived foam cell differentiation http://purl.obolibrary.org/obo/GO_0090077 foam cell differentiation The process in which a monocyte acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions. http://purl.obolibrary.org/obo/GO_0010743 regulation of macrophage derived foam cell differentiation http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the rate, frequency or extent of macrophage derived foam cell differentiation. Macrophage derived foam cell differentiation is the process in which a macrophage acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions. http://purl.obolibrary.org/obo/GO_0010744 positive regulation of macrophage derived foam cell differentiation http://purl.obolibrary.org/obo/GO_0045597 positive regulation of cell differentiation Any process that increases the rate, frequency or extent of macrophage derived foam cell differentiation. Macrophage derived foam cell differentiation is the process in which a macrophage acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions. http://purl.obolibrary.org/obo/GO_0010745 negative regulation of macrophage derived foam cell differentiation http://purl.obolibrary.org/obo/GO_0010743 regulation of macrophage derived foam cell differentiation Any process that decreases the rate, frequency or extent of macrophage derived foam cell differentiation. Macrophage derived foam cell differentiation is the process in which a macrophage acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions. http://purl.obolibrary.org/obo/GO_0010758 regulation of macrophage chemotaxis http://purl.obolibrary.org/obo/GO_1905521 regulation of macrophage migration Any process that modulates the rate, frequency or extent of macrophage chemotaxis. Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus. http://purl.obolibrary.org/obo/GO_0010759 positive regulation of macrophage chemotaxis http://purl.obolibrary.org/obo/GO_1905523 positive regulation of macrophage migration Any process that increases the rate, frequency or extent of macrophage chemotaxis. Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus. http://purl.obolibrary.org/obo/GO_0010760 negative regulation of macrophage chemotaxis http://purl.obolibrary.org/obo/GO_1905522 negative regulation of macrophage migration Any process that decreases the rate, frequency or extent of macrophage chemotaxis. Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus. http://purl.obolibrary.org/obo/GO_0010761 fibroblast migration http://purl.obolibrary.org/obo/GO_0001667 ameboidal-type cell migration Cell migration that is accomplished by extension and retraction of a fibroblast pseudopodium. A fibroblast is a connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. http://purl.obolibrary.org/obo/GO_0010762 regulation of fibroblast migration http://purl.obolibrary.org/obo/GO_0030334 regulation of cell migration Any process that modulates the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium. http://purl.obolibrary.org/obo/GO_0010763 positive regulation of fibroblast migration http://purl.obolibrary.org/obo/GO_0010762 regulation of fibroblast migration Any process that increases the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium. http://purl.obolibrary.org/obo/GO_0010764 negative regulation of fibroblast migration http://purl.obolibrary.org/obo/GO_0010762 regulation of fibroblast migration Any process that decreases the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium. http://purl.obolibrary.org/obo/GO_0010765 positive regulation of sodium ion transport http://purl.obolibrary.org/obo/GO_0043270 positive regulation of monoatomic ion transport Any process that increases the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0010766 negative regulation of sodium ion transport http://purl.obolibrary.org/obo/GO_0043271 negative regulation of monoatomic ion transport Any process that decreases the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0010770 positive regulation of cell morphogenesis http://purl.obolibrary.org/obo/GO_0022604 regulation of cell morphogenesis Any process that increases the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. http://purl.obolibrary.org/obo/GO_0010771 negative regulation of cell morphogenesis http://purl.obolibrary.org/obo/GO_0022604 regulation of cell morphogenesis Any process that decreases the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. http://purl.obolibrary.org/obo/GO_0010816 calcitonin catabolic process http://purl.obolibrary.org/obo/GO_0042447 hormone catabolic process The chemical reactions and pathways resulting in the breakdown of the peptide calcitonin. http://purl.obolibrary.org/obo/GO_0010818 T cell chemotaxis http://purl.obolibrary.org/obo/GO_0072678 T cell migration The directed movement of a T cell in response to an external stimulus. A T cell is a type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex. http://purl.obolibrary.org/obo/GO_0010819 regulation of T cell chemotaxis http://purl.obolibrary.org/obo/GO_2000404 regulation of T cell migration Any process that modulates the rate, frequency or extent of T cell chemotaxis. T cell chemotaxis is the directed movement of a T cell in response to an external stimulus. http://purl.obolibrary.org/obo/GO_0010820 positive regulation of T cell chemotaxis http://purl.obolibrary.org/obo/GO_0140131 positive regulation of lymphocyte chemotaxis Any process that increases the rate, frequency or extent of T cell chemotaxis. T cell chemotaxis is the directed movement of a T cell in response to an external stimulus. http://purl.obolibrary.org/obo/GO_0010821 regulation of mitochondrion organization http://purl.obolibrary.org/obo/GO_0033043 regulation of organelle organization Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a mitochondrion. http://purl.obolibrary.org/obo/GO_0010827 regulation of D-glucose transmembrane transport http://purl.obolibrary.org/obo/GO_0034762 regulation of transmembrane transport Any process that modulates the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0010828 positive regulation of D-glucose transmembrane transport http://purl.obolibrary.org/obo/GO_0010827 regulation of D-glucose transmembrane transport Any process that increases the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0010829 negative regulation of D-glucose transmembrane transport http://purl.obolibrary.org/obo/GO_0010827 regulation of D-glucose transmembrane transport Any process that decreases the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0010830 regulation of myotube differentiation http://purl.obolibrary.org/obo/GO_0051153 regulation of striated muscle cell differentiation Any process that modulates the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse. http://purl.obolibrary.org/obo/GO_0010831 positive regulation of myotube differentiation http://purl.obolibrary.org/obo/GO_0051155 positive regulation of striated muscle cell differentiation Any process that activates, maintains or increases the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse. http://purl.obolibrary.org/obo/GO_0010832 negative regulation of myotube differentiation http://purl.obolibrary.org/obo/GO_0051154 negative regulation of striated muscle cell differentiation Any process that decreases the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse. http://purl.obolibrary.org/obo/GO_0010837 regulation of keratinocyte proliferation http://purl.obolibrary.org/obo/GO_0050678 regulation of epithelial cell proliferation Any process that modulates the rate, frequency or extent of keratinocyte proliferation. Keratinocyte proliferation is the multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population. http://purl.obolibrary.org/obo/GO_0010838 positive regulation of keratinocyte proliferation http://purl.obolibrary.org/obo/GO_0010837 regulation of keratinocyte proliferation Any process that increases the rate, frequency or extent of keratinocyte proliferation. Keratinocyte proliferation is the multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population. http://purl.obolibrary.org/obo/GO_0010839 negative regulation of keratinocyte proliferation http://purl.obolibrary.org/obo/GO_0010837 regulation of keratinocyte proliferation Any process that decreases the rate, frequency or extent of keratinocyte proliferation. Keratinocyte proliferation is the multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population. http://purl.obolibrary.org/obo/GO_0010842 retina layer formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process in which the vertebrate retina is organized into three laminae: the outer nuclear layer (ONL), which contains photoreceptor nuclei; the inner nuclear layer (INL), which contains amacrine, bipolar and horizontal cells; and the retinal ganglion cell (RGC) layer. Between the inner and outer nuclear layers, the outer plexiform layer (OPL) contains connections between the photoreceptors and bipolar and horizontal cells. The inner plexiform layer (IPL) is positioned between the INL and the ganglion cell layer and contains the dendrites of RGCs and processes of bipolar and amacrine cells. Spanning all layers of the retina are the radially oriented Mueller glia. http://purl.obolibrary.org/obo/GO_0010882 regulation of cardiac muscle contraction by calcium ion signaling http://purl.obolibrary.org/obo/GO_0055117 regulation of cardiac muscle contraction Any process that modulates the frequency, rate or extent of cardiac muscle contraction by changing the calcium ion signals that trigger contraction. http://purl.obolibrary.org/obo/GO_0010892 positive regulation of mitochondrial translation in response to stress http://purl.obolibrary.org/obo/GO_0070131 positive regulation of mitochondrial translation Any process that activates or increases the frequency, rate or extent of mitochondrial translation as a result of a stimulus indicating the organism is under stress. http://purl.obolibrary.org/obo/GO_0010893 positive regulation of steroid biosynthetic process http://purl.obolibrary.org/obo/GO_0050810 regulation of steroid biosynthetic process Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus. http://purl.obolibrary.org/obo/GO_0010894 negative regulation of steroid biosynthetic process http://purl.obolibrary.org/obo/GO_0051055 negative regulation of lipid biosynthetic process Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus. http://purl.obolibrary.org/obo/GO_0010907 positive regulation of glucose metabolic process http://purl.obolibrary.org/obo/GO_0045913 positive regulation of carbohydrate metabolic process Any process that increases the rate, frequency or extent of glucose metabolism. Glucose metabolic processes are the chemical reactions and pathways involving glucose, the aldohexose gluco-hexose. http://purl.obolibrary.org/obo/GO_0010931 macrophage tolerance induction http://purl.obolibrary.org/obo/GO_0002507 tolerance induction A process involving any mechanism for tolerance induction in macrophages. http://purl.obolibrary.org/obo/GO_0010932 regulation of macrophage tolerance induction http://purl.obolibrary.org/obo/GO_0002643 regulation of tolerance induction Any process that modulates the frequency, rate, or extent of macrophage tolerance induction. http://purl.obolibrary.org/obo/GO_0010933 positive regulation of macrophage tolerance induction http://purl.obolibrary.org/obo/GO_0010932 regulation of macrophage tolerance induction Any process that increases the frequency, rate, or extent of B cell tolerance induction. http://purl.obolibrary.org/obo/GO_0010934 macrophage cytokine production http://purl.obolibrary.org/obo/GO_0061082 myeloid leukocyte cytokine production The appearance of a macrophage cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. http://purl.obolibrary.org/obo/GO_0010935 regulation of macrophage cytokine production http://purl.obolibrary.org/obo/GO_0002718 regulation of cytokine production involved in immune response Any process that modulates the rate, frequency or extent of macrophage cytokine production. Macrophage cytokine production is the appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. http://purl.obolibrary.org/obo/GO_0010936 negative regulation of macrophage cytokine production http://purl.obolibrary.org/obo/GO_0010935 regulation of macrophage cytokine production Any process that decreases the rate, frequency or extent of macrophage cytokine production. Macrophage cytokine production is the appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. http://purl.obolibrary.org/obo/GO_0010937 regulation of cytoplasmic microtubule depolymerization http://purl.obolibrary.org/obo/GO_0031114 regulation of microtubule depolymerization Any process that modulates the frequency, rate or extent of cytoplasmic microtubule depolymerization. http://purl.obolibrary.org/obo/GO_0010938 cytoplasmic microtubule depolymerization http://purl.obolibrary.org/obo/GO_0031122 cytoplasmic microtubule organization The removal of tubulin heterodimers from one or both ends of a cytoplasmic microtubule. http://purl.obolibrary.org/obo/GO_0010948 negative regulation of cell cycle process http://purl.obolibrary.org/obo/GO_0045786 negative regulation of cell cycle Any process that decreases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. http://purl.obolibrary.org/obo/GO_0010955 negative regulation of protein processing http://purl.obolibrary.org/obo/GO_1903318 negative regulation of protein maturation Any process that decreases the rate, frequency or extent of protein maturation by peptide bond cleavage. http://purl.obolibrary.org/obo/GO_0010958 regulation of amino acid import across plasma membrane http://purl.obolibrary.org/obo/GO_1903789 regulation of amino acid transmembrane transport Any process that modulates the frequency, rate or extent of amino acid import into a cell. http://purl.obolibrary.org/obo/GO_0010966 regulation of phosphate transport http://purl.obolibrary.org/obo/GO_0051049 regulation of transport Any process that modulates the frequency, rate or extent of phosphate transport. Phosphate transport is the directed movement of phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0010968 regulation of microtubule nucleation http://purl.obolibrary.org/obo/GO_0031113 regulation of microtubule polymerization Any process that modulates the rate, frequency or extent of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell. http://purl.obolibrary.org/obo/GO_0010975 regulation of neuron projection development http://purl.obolibrary.org/obo/GO_0120035 regulation of plasma membrane bounded cell projection organization Any process that modulates the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites). http://purl.obolibrary.org/obo/GO_0010976 positive regulation of neuron projection development http://purl.obolibrary.org/obo/GO_0031346 positive regulation of cell projection organization Any process that increases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites). http://purl.obolibrary.org/obo/GO_0010977 negative regulation of neuron projection development http://purl.obolibrary.org/obo/GO_0010975 regulation of neuron projection development Any process that decreases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites). http://purl.obolibrary.org/obo/GO_0012506 vesicle membrane http://purl.obolibrary.org/obo/GO_0031090 organelle membrane The lipid bilayer surrounding any membrane-bounded vesicle in the cell. http://purl.obolibrary.org/obo/GO_0014002 astrocyte development http://purl.obolibrary.org/obo/GO_0021782 glial cell development The process aimed at the progression of an astrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function. http://purl.obolibrary.org/obo/GO_0014003 oligodendrocyte development http://purl.obolibrary.org/obo/GO_0021782 glial cell development The process aimed at the progression of an oligodendrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. An oligodendrocyte is a type of glial cell involved in myelinating the axons in the central nervous system. http://purl.obolibrary.org/obo/GO_0014004 microglia differentiation http://purl.obolibrary.org/obo/GO_0030225 macrophage differentiation The process in which a relatively unspecialized cell acquires specialized features of a microglial cell. Microglia are glial cells that act as the immune cells of the central nervous system. They form part of the supporting structure of this system. http://purl.obolibrary.org/obo/GO_0014005 microglia development http://purl.obolibrary.org/obo/GO_0061515 myeloid cell development The process aimed at the progression of a microglial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. http://purl.obolibrary.org/obo/GO_0014006 regulation of microglia differentiation http://purl.obolibrary.org/obo/GO_0045685 regulation of glial cell differentiation Any process that modulates the frequency, rate or extent of microglia differentiation, the process in which a relatively unspecialized cell acquires specialized features of a microglial cell. http://purl.obolibrary.org/obo/GO_0014007 negative regulation of microglia differentiation http://purl.obolibrary.org/obo/GO_0045686 negative regulation of glial cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of microglia differentiation, the process in which a relatively unspecialized cell acquires specialized features of a microglial cell. http://purl.obolibrary.org/obo/GO_0014008 positive regulation of microglia differentiation http://purl.obolibrary.org/obo/GO_0045687 positive regulation of glial cell differentiation Any process that activates, maintains or increases the frequency, rate or extent of microglia differentiation, the process in which a relatively unspecialized cell acquires specialized features of a microglial cell. http://purl.obolibrary.org/obo/GO_0014009 glial cell proliferation http://purl.obolibrary.org/obo/GO_0008283 cell population proliferation The multiplication or reproduction of glial cells by cell division, resulting in the expansion of their population. Glial cells exist throughout the nervous system, and include Schwann cells, astrocytes, and oligodendrocytes among others. http://purl.obolibrary.org/obo/GO_0014010 Schwann cell proliferation http://purl.obolibrary.org/obo/GO_0014009 glial cell proliferation The multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system. http://purl.obolibrary.org/obo/GO_0014013 regulation of gliogenesis http://purl.obolibrary.org/obo/GO_0050767 regulation of neurogenesis Any process that modulates the frequency, rate or extent of gliogenesis, the formation of mature glia. http://purl.obolibrary.org/obo/GO_0014014 negative regulation of gliogenesis http://purl.obolibrary.org/obo/GO_0014013 regulation of gliogenesis Any process that stops, prevents, or reduces the frequency, rate or extent of gliogenesis, the formation of mature glia. http://purl.obolibrary.org/obo/GO_0014015 positive regulation of gliogenesis http://purl.obolibrary.org/obo/GO_0014013 regulation of gliogenesis Any process that activates or increases the frequency, rate or extent of gliogenesis, the formation of mature glia. http://purl.obolibrary.org/obo/GO_0014016 neuroblast differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a neuroblast. There are at least four stages through which the pluripotent cells of epiblast or blastula become neuroblasts. http://purl.obolibrary.org/obo/GO_0014019 neuroblast development http://purl.obolibrary.org/obo/GO_0048468 cell development The process aimed at the progression of a neuroblast over time, from initial commitment of the cell to a specific state, to the mature neuroblast. It does not include processes where the neuroblast turns into a glial cell or a neuron. http://purl.obolibrary.org/obo/GO_0014023 neural rod formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The formation of a solid rod of neurectoderm derived from the neural keel. The neural rod is roughly circular in cross section. Neural rod formation occurs during primary neurulation in teleosts. http://purl.obolibrary.org/obo/GO_0014025 neural keel formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The formation of a thickened region of the neurectoderm that is roughly triangular in cross section. The neural keel develops from the neural plate and develops into the neural rod. Neural keel formation occurs during primary neurulation in teleosts. http://purl.obolibrary.org/obo/GO_0014028 notochord formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The formation of the notochord from the chordamesoderm. The notochord is composed of large cells packed within a firm connective tissue sheath and is found in all chordates at the ventral surface of the neural tube. In vertebrates, the notochord contributes to the vertebral column. http://purl.obolibrary.org/obo/GO_0014029 neural crest formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation proceeds. http://purl.obolibrary.org/obo/GO_0014031 mesenchymal cell development http://purl.obolibrary.org/obo/GO_0048468 cell development The process aimed at the progression of a mesenchymal cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell. http://purl.obolibrary.org/obo/GO_0014033 neural crest cell differentiation http://purl.obolibrary.org/obo/GO_0048863 stem cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a neural crest cell. http://purl.obolibrary.org/obo/GO_0014037 Schwann cell differentiation http://purl.obolibrary.org/obo/GO_0010001 glial cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a Schwann cell. Schwann cells are found in the peripheral nervous system, where they insulate neurons and axons, and regulate the environment in which neurons function. http://purl.obolibrary.org/obo/GO_0014038 regulation of Schwann cell differentiation http://purl.obolibrary.org/obo/GO_0045685 regulation of glial cell differentiation Any process that modulates the frequency, rate or extent of Schwann cell differentiation. http://purl.obolibrary.org/obo/GO_0014039 negative regulation of Schwann cell differentiation http://purl.obolibrary.org/obo/GO_0045686 negative regulation of glial cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of Schwann cell differentiation. http://purl.obolibrary.org/obo/GO_0014040 positive regulation of Schwann cell differentiation http://purl.obolibrary.org/obo/GO_0045687 positive regulation of glial cell differentiation Any process that activates or increases the frequency, rate or extent of Schwann cell differentiation. http://purl.obolibrary.org/obo/GO_0014041 regulation of neuron maturation http://purl.obolibrary.org/obo/GO_0045664 regulation of neuron differentiation Any process that modulates the frequency, rate or extent of neuron maturation, the process leading to the attainment of the full functional capacity of a neuron. This process is independent of morphogenetic change. http://purl.obolibrary.org/obo/GO_0014042 positive regulation of neuron maturation http://purl.obolibrary.org/obo/GO_1903431 positive regulation of cell maturation Any process that activates or increases the frequency, rate or extent of neuron maturation. http://purl.obolibrary.org/obo/GO_0014043 negative regulation of neuron maturation http://purl.obolibrary.org/obo/GO_1903430 negative regulation of cell maturation Any process that stops, prevents, or reduces the frequency, rate or extent of neuron maturation. http://purl.obolibrary.org/obo/GO_0014044 Schwann cell development http://purl.obolibrary.org/obo/GO_0021782 glial cell development The process aimed at the progression of a Schwann cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. Schwann cells are found in the peripheral nervous system, where they insulate neurons and axons, and regulate the environment in which neurons function. http://purl.obolibrary.org/obo/GO_0014046 dopamine secretion http://purl.obolibrary.org/obo/GO_0050432 catecholamine secretion The regulated release of dopamine by a cell. Dopamine is a catecholamine and a precursor of adrenaline and noradrenaline. It acts as a neurotransmitter in the central nervous system but it is also produced peripherally and acts as a hormone. http://purl.obolibrary.org/obo/GO_0014047 glutamate secretion http://purl.obolibrary.org/obo/GO_0015800 acidic amino acid transport The controlled release of glutamate by a cell. The glutamate is the most abundant excitatory neurotransmitter in the nervous system. http://purl.obolibrary.org/obo/GO_0014048 regulation of glutamate secretion http://purl.obolibrary.org/obo/GO_0032890 regulation of organic acid transport Any process that modulates the frequency, rate or extent of the controlled release of glutamate. http://purl.obolibrary.org/obo/GO_0014049 positive regulation of glutamate secretion http://purl.obolibrary.org/obo/GO_0014048 regulation of glutamate secretion Any process that activates or increases the frequency, rate or extent of the controlled release of glutamate. http://purl.obolibrary.org/obo/GO_0014050 negative regulation of glutamate secretion http://purl.obolibrary.org/obo/GO_0014048 regulation of glutamate secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of glutamate. http://purl.obolibrary.org/obo/GO_0014051 gamma-aminobutyric acid secretion http://purl.obolibrary.org/obo/GO_0015812 gamma-aminobutyric acid transport The regulated release of gamma-aminobutyric acid by a cell or a tissue. The gamma-aminobutyric acid is the principal inhibitory neurotransmitter in the brain but is also found in several extraneural tissues. http://purl.obolibrary.org/obo/GO_0014052 regulation of gamma-aminobutyric acid secretion http://purl.obolibrary.org/obo/GO_0032890 regulation of organic acid transport Any process that modulates the frequency, rate or extent of the regulated release of gamma-aminobutyric acid. http://purl.obolibrary.org/obo/GO_0014053 negative regulation of gamma-aminobutyric acid secretion http://purl.obolibrary.org/obo/GO_0014052 regulation of gamma-aminobutyric acid secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of gamma-aminobutyric acid. http://purl.obolibrary.org/obo/GO_0014054 positive regulation of gamma-aminobutyric acid secretion http://purl.obolibrary.org/obo/GO_0014052 regulation of gamma-aminobutyric acid secretion Any process that activates or increases the frequency, rate or extent of the regulated release of gamma-aminobutyric acid. http://purl.obolibrary.org/obo/GO_0014055 acetylcholine secretion, neurotransmission http://purl.obolibrary.org/obo/GO_0061526 acetylcholine secretion The regulated release of acetylcholine by a cell. The acetylcholine acts as a neurotransmitter that acts in both the peripheral nervous system (PNS) and central nervous system (CNS). http://purl.obolibrary.org/obo/GO_0014056 regulation of acetylcholine secretion, neurotransmission http://purl.obolibrary.org/obo/GO_0051952 regulation of amine transport Any process that modulates the frequency, rate or extent of the regulated release of acetylcholine. http://purl.obolibrary.org/obo/GO_0014057 positive regulation of acetylcholine secretion, neurotransmission http://purl.obolibrary.org/obo/GO_0051954 positive regulation of amine transport Any process that activates or increases the frequency, rate or extent of the regulated release of acetylcholine. http://purl.obolibrary.org/obo/GO_0014058 negative regulation of acetylcholine secretion, neurotransmission http://purl.obolibrary.org/obo/GO_0051953 negative regulation of amine transport Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of acetylcholine. http://purl.obolibrary.org/obo/GO_0014059 regulation of dopamine secretion http://purl.obolibrary.org/obo/GO_0050433 regulation of catecholamine secretion Any process that modulates the frequency, rate or extent of the regulated release of dopamine. http://purl.obolibrary.org/obo/GO_0014060 regulation of epinephrine secretion http://purl.obolibrary.org/obo/GO_0050433 regulation of catecholamine secretion Any process that modulates the frequency, rate or extent of the regulated release of epinephrine. http://purl.obolibrary.org/obo/GO_0014061 regulation of norepinephrine secretion http://purl.obolibrary.org/obo/GO_0050433 regulation of catecholamine secretion Any process that modulates the frequency, rate or extent of the regulated release of norepinephrine. http://purl.obolibrary.org/obo/GO_0014062 regulation of serotonin secretion http://purl.obolibrary.org/obo/GO_0043269 regulation of monoatomic ion transport Any process that modulates the frequency, rate or extent of the regulated release of serotonin. http://purl.obolibrary.org/obo/GO_0014063 negative regulation of serotonin secretion http://purl.obolibrary.org/obo/GO_0043271 negative regulation of monoatomic ion transport Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of serotonin. http://purl.obolibrary.org/obo/GO_0014064 positive regulation of serotonin secretion http://purl.obolibrary.org/obo/GO_0043270 positive regulation of monoatomic ion transport Any process that activates or increases the frequency, rate or extent of the regulated release of serotonin. http://purl.obolibrary.org/obo/GO_0014074 response to purine-containing compound http://purl.obolibrary.org/obo/GO_1901698 response to nitrogen compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a purine-containing compound stimulus. http://purl.obolibrary.org/obo/GO_0014707 branchiomeric skeletal muscle development http://purl.obolibrary.org/obo/GO_0007519 skeletal muscle tissue development The process whose specific outcome is the progression of the branchiomeric skeletal muscle over time, from its formation to the mature structure. The branchiomeric muscle is derived from cranial mesoderm and controls facial expression, pharyngeal and laryngeal function, operating the jaw. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. Branchiomeric muscles of mammals correspond to the gill musculature of fish. http://purl.obolibrary.org/obo/GO_0014711 regulation of branchiomeric skeletal muscle development http://purl.obolibrary.org/obo/GO_0048641 regulation of skeletal muscle tissue development Any process that modulates the frequency, rate or extent of branchiomeric skeletal muscle development. Branchiomeric skeletal muscle development is the process whose specific outcome is the progression of the branchiomeric skeletal muscle over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0014712 positive regulation of branchiomeric skeletal muscle development http://purl.obolibrary.org/obo/GO_0048643 positive regulation of skeletal muscle tissue development Any process that activates, maintains or increases the frequency, rate or extent of branchiomeric skeletal muscle development. Branchiomeric skeletal muscle development is the process whose specific outcome is the progression of the branchiomeric skeletal muscle over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0014713 negative regulation of branchiomeric skeletal muscle development http://purl.obolibrary.org/obo/GO_0048642 negative regulation of skeletal muscle tissue development Any process that stops, prevents, or reduces the frequency, rate or extent of branchiomeric skeletal muscle development. Branchiomeric skeletal muscle development is the process whose specific outcome is the progression of the branchiomeric skeletal muscle over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0014717 regulation of satellite cell activation involved in skeletal muscle regeneration http://purl.obolibrary.org/obo/GO_0043416 regulation of skeletal muscle tissue regeneration Any process that modulates the frequency, rate or extent of satellite cell activation. The satellite cell activation is the process that initiates satellite cell division by causing it to move from quiescence to the G1 stage of the cell cycle. The cell swells and there are a number of other small changes. The cells then start to divide. Following cell division the cells will differentiate. http://purl.obolibrary.org/obo/GO_0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration http://purl.obolibrary.org/obo/GO_0043415 positive regulation of skeletal muscle tissue regeneration Any process that activates, maintains or increases the frequency, rate or extent of activation of satellite cell involved in skeletal muscle regeneration. The activation of satellite cell is the process that initiates satellite cell division by causing it to move from quiescence to the G1 stage of the cell cycle. The cell swells and there are a number of other small changes. The cells then start to divide. Following cell division the cells will differentiate. http://purl.obolibrary.org/obo/GO_0014719 skeletal muscle satellite cell activation http://purl.obolibrary.org/obo/GO_0001775 cell activation The change of a skeletal muscle satellite cell from a mitotically quiescent to a mitotically active state following exposure to some activating factor such as a cellular or soluble ligand. In adult muscle, satellite cells become activated to divide and differentiate in response to muscle damage. http://purl.obolibrary.org/obo/GO_0014722 regulation of skeletal muscle contraction by calcium ion signaling http://purl.obolibrary.org/obo/GO_0014819 regulation of skeletal muscle contraction Any process that modulates the frequency, rate or extent of skeletal muscle contraction by changing the calcium ion signals that trigger contraction. http://purl.obolibrary.org/obo/GO_0014725 regulation of extraocular skeletal muscle development http://purl.obolibrary.org/obo/GO_0048641 regulation of skeletal muscle tissue development Any process that modulates the frequency, rate or extent of extraocular skeletal muscle development. Extraocular skeletal muscle development is the process whose specific outcome is the progression of the extraocular skeletal muscle over time, from its formation to the mature structure. The extraocular muscle is derived from cranial mesoderm and controls eye movements. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. http://purl.obolibrary.org/obo/GO_0014726 negative regulation of extraocular skeletal muscle development http://purl.obolibrary.org/obo/GO_0048642 negative regulation of skeletal muscle tissue development Any process that stops, prevents, or reduces the frequency, rate or extent of extraocular skeletal muscle development. Extraocular skeletal muscle development is the process whose specific outcome is the progression of the extraocular skeletal muscle over time, from its formation to the mature structure. The extraocular muscle is derived from cranial mesoderm and controls eye movements. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. http://purl.obolibrary.org/obo/GO_0014727 positive regulation of extraocular skeletal muscle development http://purl.obolibrary.org/obo/GO_0048643 positive regulation of skeletal muscle tissue development Any process that activates, maintains or increases the frequency, rate or extent of extraocular skeletal muscle development. Extraocular skeletal muscle development is the process whose specific outcome is the progression of the extraocular skeletal muscle over time, from its formation to the mature structure. The extraocular muscle is derived from cranial mesoderm and controls eye movements. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. http://purl.obolibrary.org/obo/GO_0014733 regulation of skeletal muscle adaptation http://purl.obolibrary.org/obo/GO_0043502 regulation of muscle adaptation Any process in which skeletal muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities. http://purl.obolibrary.org/obo/GO_0014734 skeletal muscle hypertrophy http://purl.obolibrary.org/obo/GO_0043501 skeletal muscle adaptation The enlargement or overgrowth of all or part of an organ due to an increase in size (not length) of individual muscle fibers without cell division. In the case of skeletal muscle cells this happens due to the additional synthesis of sarcomeric proteins and assembly of myofibrils. http://purl.obolibrary.org/obo/GO_0014741 negative regulation of muscle hypertrophy http://purl.obolibrary.org/obo/GO_0014743 regulation of muscle hypertrophy Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle hypertrophy. http://purl.obolibrary.org/obo/GO_0014742 positive regulation of muscle hypertrophy http://purl.obolibrary.org/obo/GO_0014743 regulation of muscle hypertrophy Any process that activates or increases the frequency, rate or extent of muscle hypertrophy. http://purl.obolibrary.org/obo/GO_0014743 regulation of muscle hypertrophy http://purl.obolibrary.org/obo/GO_0090257 regulation of muscle system process Any process that modulates the frequency, rate or extent of muscle hypertrophy. http://purl.obolibrary.org/obo/GO_0014744 positive regulation of muscle adaptation http://purl.obolibrary.org/obo/GO_0043502 regulation of muscle adaptation Any process that activates or increases the frequency, rate or extent of muscle adaptation. http://purl.obolibrary.org/obo/GO_0014745 negative regulation of muscle adaptation http://purl.obolibrary.org/obo/GO_0043502 regulation of muscle adaptation Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle adaptation. http://purl.obolibrary.org/obo/GO_0014805 smooth muscle adaptation http://purl.obolibrary.org/obo/GO_0043500 muscle adaptation Any process in which smooth muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities. http://purl.obolibrary.org/obo/GO_0014807 regulation of somitogenesis http://purl.obolibrary.org/obo/GO_0051239 regulation of multicellular organismal process Any process that modulates the frequency, rate or extent of somitogenesis. http://purl.obolibrary.org/obo/GO_0014812 muscle cell migration http://purl.obolibrary.org/obo/GO_0016477 cell migration The orderly movement of a muscle cell from one site to another, often during the development of a multicellular organism. http://purl.obolibrary.org/obo/GO_0014816 skeletal muscle satellite cell differentiation http://purl.obolibrary.org/obo/GO_0035914 skeletal muscle cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a satellite cell. http://purl.obolibrary.org/obo/GO_0014819 regulation of skeletal muscle contraction http://purl.obolibrary.org/obo/GO_0006942 regulation of striated muscle contraction Any process that modulates the frequency, rate or extent of skeletal muscle contraction. http://purl.obolibrary.org/obo/GO_0014821 phasic smooth muscle contraction http://purl.obolibrary.org/obo/GO_0006939 smooth muscle contraction A process in which force is generated within phasic smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the phasic smooth muscle, the muscle contraction occurs without an ordered sarcomeric structure. Phasic smooth muscle contraction occurs in a series of discrete contractions and relaxations. http://purl.obolibrary.org/obo/GO_0014827 intestine smooth muscle contraction http://purl.obolibrary.org/obo/GO_0014831 gastro-intestinal system smooth muscle contraction A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the intestine. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The intestine is the section of the alimentary canal from the stomach to the anal canal. It includes the large intestine and small intestine. http://purl.obolibrary.org/obo/GO_0014831 gastro-intestinal system smooth muscle contraction http://purl.obolibrary.org/obo/GO_0006939 smooth muscle contraction A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the gastro-intestinal system. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The gastro-intestinal system generally refers to the digestive structures stretching from the mouth to anus, but does not include the accessory glandular organs (liver, pancreas and biliary tract). http://purl.obolibrary.org/obo/GO_0014832 urinary bladder smooth muscle contraction http://purl.obolibrary.org/obo/GO_0014848 urinary tract smooth muscle contraction A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the urinary bladder. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The urinary bladder is a musculomembranous sac along the urinary tract. http://purl.obolibrary.org/obo/GO_0014833 skeletal muscle satellite stem cell asymmetric division http://purl.obolibrary.org/obo/GO_0098722 asymmetric stem cell division The asymmetric division of a skeletal muscle satellite stem cell to produce two daughter cells, one of which is destined to differentiate and the other to be a quiescent cell that restocks the satellite cell pool. http://purl.obolibrary.org/obo/GO_0014834 skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration http://purl.obolibrary.org/obo/GO_0098727 maintenance of cell number Any process by which the number of skeletal muscle satellite cells in a skeletal muscle is maintained during muscle regeneration. There are at least three mechanisms by which this is achieved. Skeletal muscle satellite stem cell asymmetric division ensures satellite stem cell numbers are kept constant. Symmetric division of these cells amplifies the number of skeletal muscle satellite stem cells. Some adult skeletal muscle myoblasts (descendants of activated satellite cells) can develop back into quiescent satellite cells, replenishing the overall pool of satellite cells. http://purl.obolibrary.org/obo/GO_0014835 myoblast differentiation involved in skeletal muscle regeneration http://purl.obolibrary.org/obo/GO_0045445 myoblast differentiation The process in which a relatively unspecialized satellite cell acquires specialized features of a myoblast. This occurs as part of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. http://purl.obolibrary.org/obo/GO_0014839 myoblast migration involved in skeletal muscle regeneration http://purl.obolibrary.org/obo/GO_0051451 myoblast migration The process in which a myoblast migrates along an entire fiber to the site of injury. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. http://purl.obolibrary.org/obo/GO_0014841 skeletal muscle satellite cell proliferation http://purl.obolibrary.org/obo/GO_0014856 skeletal muscle cell proliferation The multiplication or reproduction of satellite cells, resulting in the expansion of the cell population. Satellite cells are quiescent cells that are located between the basal lamina and the plasmalemma of the muscle fiber, which are the main contributors to postnatal muscle growth. In adult muscle, satellite cells become activated to divide and differentiate in response to muscle damage. http://purl.obolibrary.org/obo/GO_0014842 regulation of skeletal muscle satellite cell proliferation http://purl.obolibrary.org/obo/GO_0014857 regulation of skeletal muscle cell proliferation Any process that modulates the frequency, rate or extent of skeletal muscle satellite cell proliferation. http://purl.obolibrary.org/obo/GO_0014848 urinary tract smooth muscle contraction http://purl.obolibrary.org/obo/GO_0006939 smooth muscle contraction A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the urinary tract. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The urinary tract consists of organs of the body that produce and discharge urine. These include the kidneys, ureters, bladder, and urethra. http://purl.obolibrary.org/obo/GO_0014849 ureter smooth muscle contraction http://purl.obolibrary.org/obo/GO_0014848 urinary tract smooth muscle contraction A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the ureter. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The ureter is one of a pair of thick-walled tubes that transports urine from the kidney pelvis to the urinary bladder. http://purl.obolibrary.org/obo/GO_0014852 regulation of skeletal muscle contraction by neural stimulation via neuromuscular junction http://purl.obolibrary.org/obo/GO_0014819 regulation of skeletal muscle contraction Any process that modulates the frequency, rate or extent of skeletal muscle contraction by variation of the pattern of stimulation by nervous system. http://purl.obolibrary.org/obo/GO_0014853 regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction http://purl.obolibrary.org/obo/GO_0098815 modulation of excitatory postsynaptic potential Any process, involved in skeletal muscle contraction, that modulates the establishment or extent of the excitatory postsynaptic potential (EPSP). Excitatory postsynaptic potential (EPSP) is a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential. http://purl.obolibrary.org/obo/GO_0014855 striated muscle cell proliferation http://purl.obolibrary.org/obo/GO_0033002 muscle cell proliferation The multiplication or reproduction of striated muscle cells, resulting in the expansion of a cell population. Striated muscles contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle. http://purl.obolibrary.org/obo/GO_0014856 skeletal muscle cell proliferation http://purl.obolibrary.org/obo/GO_0014855 striated muscle cell proliferation The multiplication or reproduction of skeletal muscle cells, resulting in the expansion of a cell population. http://purl.obolibrary.org/obo/GO_0014857 regulation of skeletal muscle cell proliferation http://purl.obolibrary.org/obo/GO_0042127 regulation of cell population proliferation Any process that modulates the frequency, rate or extent of skeletal muscle cell proliferation. http://purl.obolibrary.org/obo/GO_0014858 positive regulation of skeletal muscle cell proliferation http://purl.obolibrary.org/obo/GO_0014857 regulation of skeletal muscle cell proliferation Any process that activates or increases the frequency, rate or extent of skeletal muscle cell proliferation. http://purl.obolibrary.org/obo/GO_0014859 negative regulation of skeletal muscle cell proliferation http://purl.obolibrary.org/obo/GO_0014857 regulation of skeletal muscle cell proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle cell proliferation. http://purl.obolibrary.org/obo/GO_0014860 neurotransmitter secretion involved in regulation of skeletal muscle contraction http://purl.obolibrary.org/obo/GO_0007269 neurotransmitter secretion The regulated release of neurotransmitter into the synaptic cleft involved in skeletal muscle contraction. A neurotransmitter is any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell. Among the many substances that have the properties of a neurotransmitter are acetylcholine, noradrenaline, adrenaline, dopamine, glycine, gamma aminobutyrate, glutamic acid, substance P, enkephalins, endorphins and serotonin. http://purl.obolibrary.org/obo/GO_0014861 regulation of skeletal muscle contraction via regulation of action potential http://purl.obolibrary.org/obo/GO_0098900 regulation of action potential Any process that modulates the frequency, rate or extent of skeletal muscle contraction by depolarization of muscle membrane and ionic fluxes. http://purl.obolibrary.org/obo/GO_0014866 skeletal myofibril assembly http://purl.obolibrary.org/obo/GO_0030239 myofibril assembly The process whose specific outcome is the progression of the skeletal myofibril over time, from its formation to the mature structure. A skeletal myofibril is a myofibril specific to skeletal muscle cells. http://purl.obolibrary.org/obo/GO_0014872 myoblast division http://purl.obolibrary.org/obo/GO_0051301 cell division The process resulting in the physical partitioning and separation of a myoblast into daughter cells. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. http://purl.obolibrary.org/obo/GO_0014878 response to electrical stimulus involved in regulation of muscle adaptation http://purl.obolibrary.org/obo/GO_0051602 response to electrical stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus. This process occurs as part of the regulation of muscle adaptation. http://purl.obolibrary.org/obo/GO_0014887 cardiac muscle adaptation http://purl.obolibrary.org/obo/GO_0014888 striated muscle adaptation The process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. http://purl.obolibrary.org/obo/GO_0014888 striated muscle adaptation http://purl.obolibrary.org/obo/GO_0043500 muscle adaptation Any process in which striated muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities. http://purl.obolibrary.org/obo/GO_0014895 smooth muscle hypertrophy http://purl.obolibrary.org/obo/GO_0014805 smooth muscle adaptation The enlargement or overgrowth of all or part of an organ due to an increase in size of its smooth muscle cells without cell division. Physiological hypertrophy is a normal process during development, and can also occur in mature structures on demand. In the uterus, smooth muscle cells undergo hypertrophy during pregnancy. http://purl.obolibrary.org/obo/GO_0014901 satellite cell activation involved in skeletal muscle regeneration http://purl.obolibrary.org/obo/GO_0014719 skeletal muscle satellite cell activation The process that initiates skeletal muscle satellite cell division by causing it to move from quiescence to the G1 stage of the cell cycle. The cell swells and there are a number of other small changes. The cells then start to divide. Following cell division the cells will differentiate. In adult muscle, satellite cells become activated to divide and differentiate in response to muscle damage. http://purl.obolibrary.org/obo/GO_0014904 myotube cell development http://purl.obolibrary.org/obo/GO_0055002 striated muscle cell development The process aimed at the progression of a myotube cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse. http://purl.obolibrary.org/obo/GO_0014906 myotube cell development involved in skeletal muscle regeneration http://purl.obolibrary.org/obo/GO_0014904 myotube cell development The process aimed at the progression of a myotube cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. This occurs as part of the process of skeletal muscle regeneration. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse. http://purl.obolibrary.org/obo/GO_0014908 myotube differentiation involved in skeletal muscle regeneration http://purl.obolibrary.org/obo/GO_0014902 myotube differentiation The process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotube differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual myotubes can fuse to form bigger myotubes and start to contract. This process occurs as part of the process of skeletal muscle regeneration. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse. http://purl.obolibrary.org/obo/GO_0014909 smooth muscle cell migration http://purl.obolibrary.org/obo/GO_0014812 muscle cell migration The orderly movement of a smooth muscle cell from one site to another, often during the development of a multicellular organism. http://purl.obolibrary.org/obo/GO_0014910 regulation of smooth muscle cell migration http://purl.obolibrary.org/obo/GO_0030334 regulation of cell migration Any process that modulates the frequency, rate or extent of smooth muscle cell migration. http://purl.obolibrary.org/obo/GO_0014911 positive regulation of smooth muscle cell migration http://purl.obolibrary.org/obo/GO_0014910 regulation of smooth muscle cell migration Any process that activates, maintains or increases the frequency, rate or extent of smooth muscle cell migration. http://purl.obolibrary.org/obo/GO_0014912 negative regulation of smooth muscle cell migration http://purl.obolibrary.org/obo/GO_0014910 regulation of smooth muscle cell migration Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell migration. http://purl.obolibrary.org/obo/GO_0015106 bicarbonate transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity Enables the transfer of bicarbonate from one side of a membrane to the other. Bicarbonate is the hydrogencarbonate ion, HCO3-. http://purl.obolibrary.org/obo/GO_0015125 bile acid transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0170055 lipid transmembrane transporter activity Enables the transfer of bile acid from one side of a membrane to the other. Bile acids are any of a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine. http://purl.obolibrary.org/obo/GO_0015144 carbohydrate transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity Enables the transfer of carbohydrate from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0015145 monosaccharide transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0051119 sugar transmembrane transporter activity Enables the transfer of a monosaccharide from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0015159 polysaccharide transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022884 macromolecule transmembrane transporter activity Enables the transfer of polysaccharides from one side of a membrane to the other. A polysaccharide is a polymer of many (typically more than 10) monosaccharide residues linked glycosidically. http://purl.obolibrary.org/obo/GO_0015187 glycine transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0015175 neutral L-amino acid transmembrane transporter activity Enables the transfer of glycine from one side of a membrane to the other. Glycine is aminoethanoic acid. http://purl.obolibrary.org/obo/GO_0015250 water channel activity http://purl.obolibrary.org/obo/GO_0015267 channel activity Enables the energy-independent facilitated diffusion of water through a transmembrane aqueous pore or channel. http://purl.obolibrary.org/obo/GO_0015252 proton channel activity http://purl.obolibrary.org/obo/GO_0015078 proton transmembrane transporter activity Enables the facilitated diffusion of a hydrogen ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. http://purl.obolibrary.org/obo/GO_0015267 channel activity http://purl.obolibrary.org/obo/GO_0022803 passive transmembrane transporter activity Enables the energy-independent facilitated diffusion of a solute through a transmembrane aqueous pore or channel. Stereospecificity is not exhibited but this transport may be specific for a particular molecular species or class of molecules. http://purl.obolibrary.org/obo/GO_0015269 calcium-activated potassium channel activity http://purl.obolibrary.org/obo/GO_0005267 potassium channel activity Enables the transmembrane transfer of a potassium cation by a channel that opens when a calcium cation has been bound by the channel complex or one of its constituent parts. http://purl.obolibrary.org/obo/GO_0015277 kainate selective glutamate receptor activity http://purl.obolibrary.org/obo/GO_0015280 ligand-gated sodium channel activity An ionotropic glutamate receptor activity that exhibits fast gating by glutamate, acts by opening a cation channel permeable to sodium and potassium, and for which kainate is an agonist. http://purl.obolibrary.org/obo/GO_0015280 ligand-gated sodium channel activity http://purl.obolibrary.org/obo/GO_0099094 ligand-gated monoatomic cation channel activity Enables the transmembrane transfer of a sodium ion by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts. http://purl.obolibrary.org/obo/GO_0015355 secondary active monocarboxylate transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0015291 secondary active transmembrane transporter activity Catalysis of the movement of a monocarboxylate, any compound containing a single carboxyl group (COOH or COO-), by uniport, symport or antiport across a membrane by a carrier-mediated mechanism. http://purl.obolibrary.org/obo/GO_0015636 short-chain fatty acid transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0015245 fatty acid transmembrane transporter activity Enables the transfer of short-chain fatty acids from one side of a membrane to the other. A short-chain fatty acid has an aliphatic tail containing fewer than 6 carbons. http://purl.obolibrary.org/obo/GO_0015665 alcohol transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity Enables the transfer of an alcohol from one side of a membrane to the other. An alcohol is any carbon compound that contains a hydroxyl group. http://purl.obolibrary.org/obo/GO_0015669 gas transport http://purl.obolibrary.org/obo/GO_0006810 transport The directed movement of substances that are gaseous in normal living conditions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0015695 organic cation transport http://purl.obolibrary.org/obo/GO_0006810 transport The directed movement of organic cations into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organic cations are atoms or small molecules with a positive charge which contain carbon in covalent linkage. http://purl.obolibrary.org/obo/GO_0015701 bicarbonate transport http://purl.obolibrary.org/obo/GO_0015711 organic anion transport The directed movement of bicarbonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0015721 bile acid and bile salt transport http://purl.obolibrary.org/obo/GO_0006869 lipid transport The directed movement of bile acid and bile salts into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0015749 monosaccharide transmembrane transport http://purl.obolibrary.org/obo/GO_0034219 carbohydrate transmembrane transport The process in which a monosaccharide is transported across a lipid bilayer, from one side of a membrane to the other. Monosaccharides are the simplest carbohydrates; they are polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides. http://purl.obolibrary.org/obo/GO_0015774 polysaccharide transport http://purl.obolibrary.org/obo/GO_0008643 carbohydrate transport The directed movement of polysaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A polysaccharide is a polymer of many (typically more than 10) monosaccharide residues linked glycosidically. http://purl.obolibrary.org/obo/GO_0015800 acidic amino acid transport http://purl.obolibrary.org/obo/GO_0006865 amino acid transport The directed movement of acidic amino acids, amino acids with a pH below 7, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0015801 aromatic amino acid transport http://purl.obolibrary.org/obo/GO_0071705 nitrogen compound transport The directed movement of aromatic amino acids, amino acids with aromatic ring, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0015802 basic amino acid transport http://purl.obolibrary.org/obo/GO_0006865 amino acid transport The directed movement of basic amino acids, amino acids with a pH above 7, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0015807 L-amino acid transport http://purl.obolibrary.org/obo/GO_0006865 amino acid transport The directed movement of L-enantiomer amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0015812 gamma-aminobutyric acid transport http://purl.obolibrary.org/obo/GO_0006865 amino acid transport The directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0015816 glycine transport http://purl.obolibrary.org/obo/GO_0015695 organic cation transport The directed movement of glycine, aminoethanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0015849 organic acid transport http://purl.obolibrary.org/obo/GO_0006810 transport The directed movement of organic acids, any acidic compound containing carbon in covalent linkage, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0015866 ADP transport http://purl.obolibrary.org/obo/GO_0015868 purine ribonucleotide transport The directed movement of ADP, adenosine diphosphate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0015868 purine ribonucleotide transport http://purl.obolibrary.org/obo/GO_1901264 carbohydrate derivative transport The directed movement of a purine ribonucleotide, any compound consisting of a purine ribonucleoside (a purine organic base attached to a ribose sugar) esterified with (ortho)phosphate, into, out of or within a cell. http://purl.obolibrary.org/obo/GO_0015870 acetylcholine transport http://purl.obolibrary.org/obo/GO_1901374 acetate ester transport The directed movement of acetylcholine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Acetylcholine is an acetic acid ester of the organic base choline and functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions. http://purl.obolibrary.org/obo/GO_0015872 dopamine transport http://purl.obolibrary.org/obo/GO_0051937 catecholamine transport The directed movement of dopamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Dopamine is a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline. http://purl.obolibrary.org/obo/GO_0015874 norepinephrine transport http://purl.obolibrary.org/obo/GO_0051937 catecholamine transport The directed movement of norepinephrine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Norepinephrine (3,4-dihydroxyphenyl-2-aminoethanol) is a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine. http://purl.obolibrary.org/obo/GO_0015912 short-chain fatty acid transport http://purl.obolibrary.org/obo/GO_0015908 fatty acid transport The directed movement of short-chain fatty acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A short-chain fatty acid has an aliphatic tail containing fewer than 6 carbons. http://purl.obolibrary.org/obo/GO_0015913 short-chain fatty acid transmembrane transport http://purl.obolibrary.org/obo/GO_0015912 short-chain fatty acid transport The directed movement of short-chain fatty acids into a cell or organelle. A short-chain fatty acid has an aliphatic tail containing fewer than 6 carbons. http://purl.obolibrary.org/obo/GO_0015979 photosynthesis http://purl.obolibrary.org/obo/GO_0008152 metabolic process The synthesis by organisms of organic chemical compounds, especially carbohydrates, from carbon dioxide (CO2) using energy obtained from light rather than from the oxidation of chemical compounds. http://purl.obolibrary.org/obo/GO_0016031 tRNA import into mitochondrion http://purl.obolibrary.org/obo/GO_0035927 RNA import into mitochondrion The process in which a tRNA is transported from the cytosol into the mitochondrial matrix. http://purl.obolibrary.org/obo/GO_0016048 detection of temperature stimulus http://purl.obolibrary.org/obo/GO_0009582 detection of abiotic stimulus The series of events in which a temperature stimulus (hot or cold) is received and converted into a molecular signal. http://purl.obolibrary.org/obo/GO_0016053 organic acid biosynthetic process http://purl.obolibrary.org/obo/GO_0044283 small molecule biosynthetic process The chemical reactions and pathways resulting in the formation of organic acids, any acidic compound containing carbon in covalent linkage. http://purl.obolibrary.org/obo/GO_0016054 organic acid catabolic process http://purl.obolibrary.org/obo/GO_0044282 small molecule catabolic process The chemical reactions and pathways resulting in the breakdown of organic acids, any acidic compound containing carbon in covalent linkage. http://purl.obolibrary.org/obo/GO_0016057 regulation of membrane potential in photoreceptor cell http://purl.obolibrary.org/obo/GO_0042391 regulation of membrane potential Hyperpolarization (vertebrates) or depolarization (invertebrates) of the photoreceptor cell membrane via closing/opening of cation specific channels as a result of signals generated by rhodopsin activation by a photon. http://purl.obolibrary.org/obo/GO_0016079 synaptic vesicle exocytosis http://purl.obolibrary.org/obo/GO_0099003 vesicle-mediated transport in synapse Fusion of intracellular membrane-bounded vesicles with the pre-synaptic membrane of the neuronal cell resulting in release of neurotransmitter into the synaptic cleft. http://purl.obolibrary.org/obo/GO_0016109 tetraterpenoid biosynthetic process http://purl.obolibrary.org/obo/GO_0016114 terpenoid biosynthetic process The chemical reactions and pathways resulting in the formation of tetraterpenoid compounds, terpenoids with eight isoprene units. http://purl.obolibrary.org/obo/GO_0016110 tetraterpenoid catabolic process http://purl.obolibrary.org/obo/GO_0016115 terpenoid catabolic process The chemical reactions and pathways resulting in the breakdown of tetraterpenoid compounds, terpenoids with eight isoprene units. http://purl.obolibrary.org/obo/GO_0016114 terpenoid biosynthetic process http://purl.obolibrary.org/obo/GO_0008299 isoprenoid biosynthetic process The chemical reactions and pathways resulting in the formation of terpenoids, any member of a class of compounds characterized by an isoprenoid chemical structure. http://purl.obolibrary.org/obo/GO_0016115 terpenoid catabolic process http://purl.obolibrary.org/obo/GO_0008300 isoprenoid catabolic process The chemical reactions and pathways resulting in the breakdown of terpenoids, any member of a class of compounds characterized by an isoprenoid chemical structure. http://purl.obolibrary.org/obo/GO_0016116 carotenoid metabolic process http://purl.obolibrary.org/obo/GO_0006721 terpenoid metabolic process The chemical reactions and pathways involving carotenoids, tetraterpenoid compounds in which two units of 4 isoprenoid residues joined head-to-tail are themselves joined tail-to-tail. http://purl.obolibrary.org/obo/GO_0016117 carotenoid biosynthetic process http://purl.obolibrary.org/obo/GO_0016116 carotenoid metabolic process The chemical reactions and pathways resulting in the formation of carotenoids, tetraterpenoid compounds in which two units of 4 isoprenoid residues joined head-to-tail are themselves joined tail-to-tail. http://purl.obolibrary.org/obo/GO_0016118 carotenoid catabolic process http://purl.obolibrary.org/obo/GO_0016116 carotenoid metabolic process The chemical reactions and pathways resulting in the breakdown of carotenoids, tetraterpenoid compounds in which two units of 4 isoprenoid residues joined head-to-tail are themselves joined tail-to-tail. http://purl.obolibrary.org/obo/GO_0016122 xanthophyll metabolic process http://purl.obolibrary.org/obo/GO_0016116 carotenoid metabolic process The chemical reactions and pathways involving xanthophylls, oxygen-containing carotenoids. http://purl.obolibrary.org/obo/GO_0016123 xanthophyll biosynthetic process http://purl.obolibrary.org/obo/GO_0016122 xanthophyll metabolic process The chemical reactions and pathways resulting in the formation of xanthophylls, oxygen-containing carotenoids. http://purl.obolibrary.org/obo/GO_0016124 xanthophyll catabolic process http://purl.obolibrary.org/obo/GO_0016122 xanthophyll metabolic process The chemical reactions and pathways resulting in the breakdown of xanthophylls, oxygen-containing carotenoids. http://purl.obolibrary.org/obo/GO_0016202 regulation of striated muscle tissue development http://purl.obolibrary.org/obo/GO_1901861 regulation of muscle tissue development Any process that modulates the frequency, rate or extent of striated muscle development. http://purl.obolibrary.org/obo/GO_0016319 mushroom body development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the mushroom body over time, from its formation to the mature structure. The mushroom body is composed of the prominent neuropil structures of the insect central brain, thought to be crucial for olfactory associated learning. These consist mainly of a bulbous calyx and tightly packaged arrays of thin parallel fibers of the Kenyon cells. http://purl.obolibrary.org/obo/GO_0016321 female meiosis chromosome segregation http://purl.obolibrary.org/obo/GO_0045132 meiotic chromosome segregation The cell cycle process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during the meiotic cell cycle in a female. http://purl.obolibrary.org/obo/GO_0016525 negative regulation of angiogenesis http://purl.obolibrary.org/obo/GO_2000181 negative regulation of blood vessel morphogenesis Any process that stops, prevents, or reduces the frequency, rate or extent of angiogenesis. http://purl.obolibrary.org/obo/GO_0016528 sarcoplasm http://purl.obolibrary.org/obo/GO_0005737 cytoplasm The cytoplasm of a muscle cell; includes the sarcoplasmic reticulum. http://purl.obolibrary.org/obo/GO_0016594 glycine binding http://purl.obolibrary.org/obo/GO_0043169 cation binding Binding to glycine, aminoethanoic acid. http://purl.obolibrary.org/obo/GO_0016597 amino acid binding http://purl.obolibrary.org/obo/GO_0005488 binding Binding to an amino acid, organic acids containing one or more amino substituents. http://purl.obolibrary.org/obo/GO_0016746 acyltransferase activity http://purl.obolibrary.org/obo/GO_0016740 transferase activity Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor). http://purl.obolibrary.org/obo/GO_0016817 hydrolase activity, acting on acid anhydrides http://purl.obolibrary.org/obo/GO_0016787 hydrolase activity Catalysis of the hydrolysis of any acid anhydride. http://purl.obolibrary.org/obo/GO_0016922 nuclear receptor binding http://purl.obolibrary.org/obo/GO_0061629 RNA polymerase II-specific DNA-binding transcription factor binding Binding to a nuclear receptor protein. Nuclear receptor proteins are DNA-binding transcription factors which are regulated by binding to a ligand. http://purl.obolibrary.org/obo/GO_0017046 peptide hormone binding http://purl.obolibrary.org/obo/GO_0042562 hormone binding Binding to a peptide with hormonal activity in animals. http://purl.obolibrary.org/obo/GO_0017126 nucleologenesis http://purl.obolibrary.org/obo/GO_0044085 cellular component biogenesis A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a nucleolus, a small, dense body one or more of which are present in the nucleus of eukaryotic cells. http://purl.obolibrary.org/obo/GO_0017145 stem cell division http://purl.obolibrary.org/obo/GO_0051301 cell division The self-renewing division of a stem cell. A stem cell is an undifferentiated cell, in the embryo or adult, that can undergo unlimited division and give rise to one or several different cell types. http://purl.obolibrary.org/obo/GO_0017156 calcium-ion regulated exocytosis http://purl.obolibrary.org/obo/GO_0045055 regulated exocytosis The release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle by fusion of the vesicle with the plasma membrane of a cell, induced by a rise in cytosolic calcium-ion levels. http://purl.obolibrary.org/obo/GO_0017158 regulation of calcium ion-dependent exocytosis http://purl.obolibrary.org/obo/GO_1903305 regulation of regulated secretory pathway Any process that modulates the frequency, rate or extent of calcium ion-dependent exocytosis. http://purl.obolibrary.org/obo/GO_0019222 regulation of metabolic process http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism. http://purl.obolibrary.org/obo/GO_0019252 starch biosynthetic process http://purl.obolibrary.org/obo/GO_0009250 glucan biosynthetic process The chemical reactions and pathways resulting in the formation of starch, the most important reserve polysaccharide in plants. http://purl.obolibrary.org/obo/GO_0019750 chloroplast localization http://purl.obolibrary.org/obo/GO_0051644 plastid localization Any process in which a chloroplast is transported to, and/or maintained in, a specific location within the cell. A chloroplast is a chlorophyll-containing plastid found in cells of algae and higher plants. http://purl.obolibrary.org/obo/GO_0019827 stem cell population maintenance http://purl.obolibrary.org/obo/GO_0098727 maintenance of cell number The process by which an organism or tissue maintains a population of stem cells of a single type. This can be achieved by a number of mechanisms: stem cell asymmetric division maintains stem cell numbers; stem cell symmetric division increases them; maintenance of a stem cell niche maintains the conditions for commitment to the stem cell fate for some types of stem cell; stem cells may arise de novo from other cell types. http://purl.obolibrary.org/obo/GO_0019867 outer membrane http://purl.obolibrary.org/obo/GO_0016020 membrane The external membrane of Gram-negative bacteria or certain organelles such as mitochondria and chloroplasts; freely permeable to most ions and metabolites. http://purl.obolibrary.org/obo/GO_0021782 glial cell development http://purl.obolibrary.org/obo/GO_0048468 cell development The process aimed at the progression of a glial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. http://purl.obolibrary.org/obo/GO_0022406 membrane docking http://purl.obolibrary.org/obo/GO_0009987 cellular process The initial attachment of a membrane or protein to a target membrane. Docking requires only that the proteins come close enough to interact and adhere. http://purl.obolibrary.org/obo/GO_0022604 regulation of cell morphogenesis http://purl.obolibrary.org/obo/GO_0022603 regulation of anatomical structure morphogenesis Any process that modulates the frequency, rate or extent of cell morphogenesis. Cell morphogenesis is the developmental process in which the shape of a cell is generated and organized. http://purl.obolibrary.org/obo/GO_0022617 extracellular matrix disassembly http://purl.obolibrary.org/obo/GO_0030198 extracellular matrix organization A process that results in the breakdown of the extracellular matrix. http://purl.obolibrary.org/obo/GO_0022803 passive transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity Enables the transfer of a single solute from one side of a membrane to the other by a mechanism involving conformational change, either by facilitated diffusion or in a membrane potential dependent process if the solute is charged. http://purl.obolibrary.org/obo/GO_0022804 active transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity Enables the transfer of a specific substance or related group of substances from one side of a membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction. http://purl.obolibrary.org/obo/GO_0022834 ligand-gated channel activity http://purl.obolibrary.org/obo/GO_0022836 gated channel activity Enables the transmembrane transfer of a solute by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts. http://purl.obolibrary.org/obo/GO_0022884 macromolecule transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity Enables the transfer of a macromolecule from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0030007 intracellular potassium ion homeostasis http://purl.obolibrary.org/obo/GO_0055075 potassium ion homeostasis A homeostatic process involved in the maintenance of a steady state level of potassium ions within a cell. http://purl.obolibrary.org/obo/GO_0030166 proteoglycan biosynthetic process http://purl.obolibrary.org/obo/GO_0009101 glycoprotein biosynthetic process The chemical reactions and pathways resulting in the formation of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans. http://purl.obolibrary.org/obo/GO_0030168 platelet activation http://purl.obolibrary.org/obo/GO_0001775 cell activation A series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. These events include shape change, adhesiveness, aggregation, and release reactions. When carried through to completion, these events lead to the formation of a stable hemostatic plug. http://purl.obolibrary.org/obo/GO_0030193 regulation of blood coagulation http://purl.obolibrary.org/obo/GO_1900046 regulation of hemostasis Any process that modulates the frequency, rate or extent of blood coagulation. http://purl.obolibrary.org/obo/GO_0030195 negative regulation of blood coagulation http://purl.obolibrary.org/obo/GO_0030193 regulation of blood coagulation Any process that stops, prevents, or reduces the frequency, rate or extent of blood coagulation. http://purl.obolibrary.org/obo/GO_0030198 extracellular matrix organization http://purl.obolibrary.org/obo/GO_0045229 external encapsulating structure organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix. http://purl.obolibrary.org/obo/GO_0030225 macrophage differentiation http://purl.obolibrary.org/obo/GO_1903131 mononuclear cell differentiation The process in which a relatively unspecialized monocyte acquires the specialized features of a macrophage. http://purl.obolibrary.org/obo/GO_0030239 myofibril assembly http://purl.obolibrary.org/obo/GO_0140694 membraneless organelle assembly Formation of myofibrils, the repeating units of striated muscle. http://purl.obolibrary.org/obo/GO_0030397 membrane disassembly http://purl.obolibrary.org/obo/GO_0061024 membrane organization The controlled breakdown of any cell membrane in the context of a normal process such as autophagy. http://purl.obolibrary.org/obo/GO_0030574 collagen catabolic process http://purl.obolibrary.org/obo/GO_0032963 collagen metabolic process The proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix, usually carried out by proteases secreted by nearby cells. http://purl.obolibrary.org/obo/GO_0030658 transport vesicle membrane http://purl.obolibrary.org/obo/GO_0030659 cytoplasmic vesicle membrane The lipid bilayer surrounding a transport vesicle. http://purl.obolibrary.org/obo/GO_0030660 Golgi-associated vesicle membrane http://purl.obolibrary.org/obo/GO_0030659 cytoplasmic vesicle membrane The lipid bilayer surrounding a vesicle associated with the Golgi apparatus. http://purl.obolibrary.org/obo/GO_0030662 coated vesicle membrane http://purl.obolibrary.org/obo/GO_0030659 cytoplasmic vesicle membrane The lipid bilayer surrounding a coated vesicle. http://purl.obolibrary.org/obo/GO_0030665 clathrin-coated vesicle membrane http://purl.obolibrary.org/obo/GO_0030662 coated vesicle membrane The lipid bilayer surrounding a clathrin-coated vesicle. http://purl.obolibrary.org/obo/GO_0030705 cytoskeleton-dependent intracellular transport http://purl.obolibrary.org/obo/GO_0046907 intracellular transport The directed movement of substances along cytoskeletal fibers such as microfilaments or microtubules within a cell. http://purl.obolibrary.org/obo/GO_0030951 establishment or maintenance of microtubule cytoskeleton polarity http://purl.obolibrary.org/obo/GO_0030952 establishment or maintenance of cytoskeleton polarity Any cellular process that results in the specification, formation or maintenance of polarized microtubule-based cytoskeletal structures. http://purl.obolibrary.org/obo/GO_0031032 actomyosin structure organization http://purl.obolibrary.org/obo/GO_0030036 actin cytoskeleton organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures containing both actin and myosin or paramyosin. The myosin may be organized into filaments. http://purl.obolibrary.org/obo/GO_0031090 organelle membrane http://purl.obolibrary.org/obo/GO_0016020 membrane A membrane that is one of the two lipid bilayers of an organelle envelope or the outermost membrane of single membrane bound organelle. http://purl.obolibrary.org/obo/GO_0031113 regulation of microtubule polymerization http://purl.obolibrary.org/obo/GO_0031110 regulation of microtubule polymerization or depolymerization Any process that modulates the frequency, rate or extent of microtubule polymerization. http://purl.obolibrary.org/obo/GO_0031122 cytoplasmic microtubule organization http://purl.obolibrary.org/obo/GO_0000226 microtubule cytoskeleton organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins in the cytoplasm of a cell. http://purl.obolibrary.org/obo/GO_0031344 regulation of cell projection organization http://purl.obolibrary.org/obo/GO_0051128 regulation of cellular component organization Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections. http://purl.obolibrary.org/obo/GO_0031346 positive regulation of cell projection organization http://purl.obolibrary.org/obo/GO_0051130 positive regulation of cellular component organization Any process that activates or increases the frequency, rate or extent of the process involved in the formation, arrangement of constituent parts, or disassembly of cell projections. http://purl.obolibrary.org/obo/GO_0031347 regulation of defense response http://purl.obolibrary.org/obo/GO_0080134 regulation of response to stress Any process that modulates the frequency, rate or extent of a defense response. http://purl.obolibrary.org/obo/GO_0031514 motile cilium http://purl.obolibrary.org/obo/GO_0005929 cilium A cilium which may have a variable arrangement of axonemal microtubules and also contains molecular motors. It may beat with a whip-like pattern that promotes cell motility or transport of fluids and other cells across a cell surface, such as on epithelial cells that line the lumenal ducts of various tissues; or they may display a distinct twirling motion that directs fluid flow asymmetrically across the cellular surface to affect asymmetric body plan organization. Motile cilia can be found in single as well as multiple copies per cell. http://purl.obolibrary.org/obo/GO_0031969 chloroplast membrane http://purl.obolibrary.org/obo/GO_0042170 plastid membrane Either of the lipid bilayers that surround a chloroplast and form the chloroplast envelope. http://purl.obolibrary.org/obo/GO_0031982 vesicle http://purl.obolibrary.org/obo/GO_0043227 membrane-bounded organelle Any small, fluid-filled, spherical organelle enclosed by membrane. http://purl.obolibrary.org/obo/GO_0032056 positive regulation of translation in response to stress http://purl.obolibrary.org/obo/GO_0045727 positive regulation of translation Any process that activates or increases the frequency, rate or extent of translation as a result of a stimulus indicating the organism is under stress. http://purl.obolibrary.org/obo/GO_0032102 negative regulation of response to external stimulus http://purl.obolibrary.org/obo/GO_0048585 negative regulation of response to stimulus Any process that stops, prevents, or reduces the frequency, rate or extent of a response to an external stimulus. http://purl.obolibrary.org/obo/GO_0032222 regulation of synaptic transmission, cholinergic http://purl.obolibrary.org/obo/GO_0050804 modulation of chemical synaptic transmission Any process that modulates the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine. http://purl.obolibrary.org/obo/GO_0032223 negative regulation of synaptic transmission, cholinergic http://purl.obolibrary.org/obo/GO_0032222 regulation of synaptic transmission, cholinergic Any process that stops, prevents, or reduces the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine. http://purl.obolibrary.org/obo/GO_0032224 positive regulation of synaptic transmission, cholinergic http://purl.obolibrary.org/obo/GO_0032222 regulation of synaptic transmission, cholinergic Any process that activates, maintains or increases the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine. http://purl.obolibrary.org/obo/GO_0032413 negative regulation of ion transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0034766 negative regulation of monoatomic ion transmembrane transport Any process that stops or reduces the activity of an ion transporter. http://purl.obolibrary.org/obo/GO_0032535 regulation of cellular component size http://purl.obolibrary.org/obo/GO_0090066 regulation of anatomical structure size A process that modulates the size of a cellular component. http://purl.obolibrary.org/obo/GO_0032553 ribonucleotide binding http://purl.obolibrary.org/obo/GO_0097367 carbohydrate derivative binding Binding to a ribonucleotide, any compound consisting of a ribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety. http://purl.obolibrary.org/obo/GO_0032782 bile acid secretion http://purl.obolibrary.org/obo/GO_0046717 acid secretion The regulated release of bile acid, composed of any of a group of steroid carboxylic acids occurring in bile, by a cell or a tissue. http://purl.obolibrary.org/obo/GO_0032869 cellular response to insulin stimulus http://purl.obolibrary.org/obo/GO_0071375 cellular response to peptide hormone stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms. http://purl.obolibrary.org/obo/GO_0032870 cellular response to hormone stimulus http://purl.obolibrary.org/obo/GO_0009725 response to hormone Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus. http://purl.obolibrary.org/obo/GO_0032879 regulation of localization http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process Any process that modulates the frequency, rate or extent of any process in which a cell, a substance, or a cellular entity is transported to, or maintained in, a specific location. http://purl.obolibrary.org/obo/GO_0032885 regulation of polysaccharide biosynthetic process http://purl.obolibrary.org/obo/GO_0032881 regulation of polysaccharide metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of polysaccharides. http://purl.obolibrary.org/obo/GO_0032963 collagen metabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process The chemical reactions and pathways involving collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%). http://purl.obolibrary.org/obo/GO_0033002 muscle cell proliferation http://purl.obolibrary.org/obo/GO_0008283 cell population proliferation The expansion of a muscle cell population by cell division. http://purl.obolibrary.org/obo/GO_0033047 regulation of mitotic sister chromatid segregation http://purl.obolibrary.org/obo/GO_0033045 regulation of sister chromatid segregation Any process that modulates the frequency, rate or extent of sister chromatid segregation during mitosis. http://purl.obolibrary.org/obo/GO_0033604 negative regulation of catecholamine secretion http://purl.obolibrary.org/obo/GO_0051953 negative regulation of amine transport Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a catecholamine. http://purl.obolibrary.org/obo/GO_0033605 positive regulation of catecholamine secretion http://purl.obolibrary.org/obo/GO_0051954 positive regulation of amine transport Any process that activates or increases the frequency, rate or extent of the regulated release of a catecholamine. http://purl.obolibrary.org/obo/GO_0033993 response to lipid http://purl.obolibrary.org/obo/GO_0042221 response to chemical Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid stimulus. http://purl.obolibrary.org/obo/GO_0034219 carbohydrate transmembrane transport http://purl.obolibrary.org/obo/GO_0055085 transmembrane transport The process in which a carbohydrate is transported across a membrane. http://purl.obolibrary.org/obo/GO_0034220 monoatomic ion transmembrane transport http://purl.obolibrary.org/obo/GO_0055085 transmembrane transport A process in which a monoatomic ion is transported across a membrane. Monatomic ions (also called simple ions) are ions consisting of exactly one atom. http://purl.obolibrary.org/obo/GO_0034284 response to monosaccharide http://purl.obolibrary.org/obo/GO_0009743 response to carbohydrate Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monosaccharide stimulus. http://purl.obolibrary.org/obo/GO_0034654 nucleobase-containing compound biosynthetic process http://purl.obolibrary.org/obo/GO_0009058 biosynthetic process The chemical reactions and pathways resulting in the formation of nucleobases, nucleosides, nucleotides and nucleic acids. http://purl.obolibrary.org/obo/GO_0034703 cation channel complex http://purl.obolibrary.org/obo/GO_0034702 monoatomic ion channel complex An ion channel complex through which cations pass. http://purl.obolibrary.org/obo/GO_0035435 phosphate ion transmembrane transport http://purl.obolibrary.org/obo/GO_0055085 transmembrane transport The process in which a phosphate is transported across a membrane. http://purl.obolibrary.org/obo/GO_0035914 skeletal muscle cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a skeletal muscle cell, a somatic cell located in skeletal muscle. http://purl.obolibrary.org/obo/GO_0035927 RNA import into mitochondrion http://purl.obolibrary.org/obo/GO_0055085 transmembrane transport The process in which a rRNA, ribosomal ribonucleic acid, is transported from the cytosol into the mitochondrial matrix. http://purl.obolibrary.org/obo/GO_0038187 pattern recognition receptor activity http://purl.obolibrary.org/obo/GO_0038023 signaling receptor activity Combining with a pathogen-associated molecular pattern (PAMP), a structure conserved among microbial species to initiate an innate immune response. http://purl.obolibrary.org/obo/GO_0042048 olfactory behavior http://purl.obolibrary.org/obo/GO_0007635 chemosensory behavior The behavior of an organism in response to an odor. http://purl.obolibrary.org/obo/GO_0042063 gliogenesis http://purl.obolibrary.org/obo/GO_0022008 neurogenesis The process that results in the generation of glial cells. This includes the production of glial progenitors and their differentiation into mature glia. http://purl.obolibrary.org/obo/GO_0042166 acetylcholine binding http://purl.obolibrary.org/obo/GO_0043169 cation binding Binding to acetylcholine, an acetic acid ester of the organic base choline that functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions. http://purl.obolibrary.org/obo/GO_0042170 plastid membrane http://purl.obolibrary.org/obo/GO_0031090 organelle membrane Either of the lipid bilayers that surround a plastid and form the plastid envelope. http://purl.obolibrary.org/obo/GO_0042435 indole-containing compound biosynthetic process http://purl.obolibrary.org/obo/GO_0009058 biosynthetic process The chemical reactions and pathways resulting in the formation of compounds that contain an indole (2,3-benzopyrrole) skeleton. http://purl.obolibrary.org/obo/GO_0042445 hormone metabolic process http://purl.obolibrary.org/obo/GO_0010817 regulation of hormone levels The chemical reactions and pathways involving any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone. http://purl.obolibrary.org/obo/GO_0042491 inner ear auditory receptor cell differentiation http://purl.obolibrary.org/obo/GO_0060113 inner ear receptor cell differentiation The process in which a relatively unspecialized inner cell acquires specialized features of an auditory hair cell. http://purl.obolibrary.org/obo/GO_0042551 neuron maturation http://purl.obolibrary.org/obo/GO_0048469 cell maturation A developmental process, independent of morphogenetic (shape) change, that is required for a neuron to attain its fully functional state. http://purl.obolibrary.org/obo/GO_0042646 plastid nucleoid http://purl.obolibrary.org/obo/GO_0009295 nucleoid The region of a plastid to which the DNA is confined. http://purl.obolibrary.org/obo/GO_0042742 defense response to bacterium http://purl.obolibrary.org/obo/GO_0009617 response to bacterium Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism. http://purl.obolibrary.org/obo/GO_0042762 regulation of sulfur metabolic process http://purl.obolibrary.org/obo/GO_0019222 regulation of metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving sulfur, the nonmetallic element sulfur or compounds that contain sulfur. http://purl.obolibrary.org/obo/GO_0042923 neuropeptide binding http://purl.obolibrary.org/obo/GO_0042277 peptide binding Interacting selectively and non-covalently and stoichiometrically with neuropeptides, peptides with direct synaptic effects (peptide neurotransmitters) or indirect modulatory effects on the nervous system (peptide neuromodulators). http://purl.obolibrary.org/obo/GO_0043065 positive regulation of apoptotic process http://purl.obolibrary.org/obo/GO_0043068 positive regulation of programmed cell death Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process. http://purl.obolibrary.org/obo/GO_0043067 regulation of programmed cell death http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes. http://purl.obolibrary.org/obo/GO_0043068 positive regulation of programmed cell death http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes. http://purl.obolibrary.org/obo/GO_0043169 cation binding http://purl.obolibrary.org/obo/GO_0043167 ion binding Binding to a cation, a charged atom or group of atoms with a net positive charge. http://purl.obolibrary.org/obo/GO_0043200 response to amino acid http://purl.obolibrary.org/obo/GO_0001101 response to acid chemical Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups. http://purl.obolibrary.org/obo/GO_0043228 membraneless organelle http://purl.obolibrary.org/obo/GO_0043226 organelle Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane. Includes ribosomes, the cytoskeleton and chromosomes. http://purl.obolibrary.org/obo/GO_0043269 regulation of monoatomic ion transport http://purl.obolibrary.org/obo/GO_0051049 regulation of transport Any process that modulates the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0043270 positive regulation of monoatomic ion transport http://purl.obolibrary.org/obo/GO_0051050 positive regulation of transport Any process that activates or increases the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0043271 negative regulation of monoatomic ion transport http://purl.obolibrary.org/obo/GO_0051051 negative regulation of transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0043403 skeletal muscle tissue regeneration http://purl.obolibrary.org/obo/GO_0042246 tissue regeneration The regrowth of skeletal muscle tissue to repair injured or damaged muscle fibers in the postnatal stage. http://purl.obolibrary.org/obo/GO_0043415 positive regulation of skeletal muscle tissue regeneration http://purl.obolibrary.org/obo/GO_0043416 regulation of skeletal muscle tissue regeneration Any process that activates or increase the rate of skeletal muscle regeneration. http://purl.obolibrary.org/obo/GO_0043416 regulation of skeletal muscle tissue regeneration http://purl.obolibrary.org/obo/GO_0048638 regulation of developmental growth Any process that modulates the frequency, rate or extent of skeletal muscle. http://purl.obolibrary.org/obo/GO_0043462 regulation of ATP-dependent activity http://purl.obolibrary.org/obo/GO_0065009 regulation of molecular function Any process that modulates the rate of an ATP-dependent activity. http://purl.obolibrary.org/obo/GO_0043501 skeletal muscle adaptation http://purl.obolibrary.org/obo/GO_0014888 striated muscle adaptation Any process in which skeletal muscles change their phenotypic profiles in response to altered functional demands and a variety of signals. http://purl.obolibrary.org/obo/GO_0043502 regulation of muscle adaptation http://purl.obolibrary.org/obo/GO_0048583 regulation of response to stimulus Any process that modulates the frequency, rate or extent of muscle adaptation. http://purl.obolibrary.org/obo/GO_0043542 endothelial cell migration http://purl.obolibrary.org/obo/GO_0016477 cell migration The orderly movement of an endothelial cell into the extracellular matrix to form an endothelium. http://purl.obolibrary.org/obo/GO_0043558 regulation of translational initiation in response to stress http://purl.obolibrary.org/obo/GO_0043555 regulation of translation in response to stress Any process that modulates the frequency, rate or extent of translation initiation, as a result of a stimulus indicating the organism is under stress. http://purl.obolibrary.org/obo/GO_0043572 plastid fission http://purl.obolibrary.org/obo/GO_0048285 organelle fission The creation of two or more plastids by division of one plastid. A plastid is any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. http://purl.obolibrary.org/obo/GO_0043616 keratinocyte proliferation http://purl.obolibrary.org/obo/GO_0050673 epithelial cell proliferation The multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population. Keratinocytes are epidermal cells which synthesize keratin and undergo a characteristic change as they move upward from the basal layers of the epidermis to the cornified (horny) layer of the skin. http://purl.obolibrary.org/obo/GO_0044085 cellular component biogenesis http://purl.obolibrary.org/obo/GO_0071840 cellular component organization or biogenesis A process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component. Includes biosynthesis of constituent macromolecules, and those macromolecular modifications that are involved in synthesis or assembly of the cellular component. http://purl.obolibrary.org/obo/GO_0044089 positive regulation of cellular component biogenesis http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the frequency, rate or extent of cellular component biogenesis, a process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component. http://purl.obolibrary.org/obo/GO_0044091 membrane biogenesis http://purl.obolibrary.org/obo/GO_0044085 cellular component biogenesis A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a membrane. http://purl.obolibrary.org/obo/GO_0044419 biological process involved in interspecies interaction between organisms http://purl.obolibrary.org/obo/GO_0008150 biological_process Any process evolved to enable an interaction with an organism of a different species. http://purl.obolibrary.org/obo/GO_0044743 protein transmembrane import into intracellular organelle http://purl.obolibrary.org/obo/GO_0033365 protein localization to organelle The directed movement of proteins into an intracellular organelle, across a membrane. http://purl.obolibrary.org/obo/GO_0045117 azole transmembrane transport http://purl.obolibrary.org/obo/GO_0071705 nitrogen compound transport The directed movement of azoles, heterocyclic compounds found in many biologically important substances, across a lipid bilayer, across a membrane. http://purl.obolibrary.org/obo/GO_0045137 development of primary sexual characteristics http://purl.obolibrary.org/obo/GO_0003006 developmental process involved in reproduction The process whose specific outcome is the progression of the primary sexual characteristics over time, from their formation to the mature structures. The primary sexual characteristics are the testes in males and the ovaries in females and they develop in response to sex hormone secretion. http://purl.obolibrary.org/obo/GO_0045177 apical part of cell http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure The region of a polarized cell that forms a tip or is distal to a base. For example, in a polarized epithelial cell, the apical region has an exposed surface and lies opposite to the basal lamina that separates the epithelium from other tissue. http://purl.obolibrary.org/obo/GO_0045184 establishment of protein localization http://purl.obolibrary.org/obo/GO_0051234 establishment of localization The directed movement of a protein to a specific location. http://purl.obolibrary.org/obo/GO_0045229 external encapsulating structure organization http://purl.obolibrary.org/obo/GO_0016043 cellular component organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of external structures that lie outside the plasma membrane and surround the entire cell. http://purl.obolibrary.org/obo/GO_0045445 myoblast differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into striated muscle fibers. http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of cell differentiation, the process in which relatively unspecialized cells acquire specialized structural and functional features. http://purl.obolibrary.org/obo/GO_0045597 positive regulation of cell differentiation http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the frequency, rate or extent of cell differentiation. http://purl.obolibrary.org/obo/GO_0045608 negative regulation of inner ear auditory receptor cell differentiation http://purl.obolibrary.org/obo/GO_2000981 negative regulation of inner ear receptor cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of auditory hair cell differentiation. http://purl.obolibrary.org/obo/GO_0045646 regulation of erythrocyte differentiation http://purl.obolibrary.org/obo/GO_0045637 regulation of myeloid cell differentiation Any process that modulates the frequency, rate or extent of erythrocyte differentiation. http://purl.obolibrary.org/obo/GO_0045649 regulation of macrophage differentiation http://purl.obolibrary.org/obo/GO_0002761 regulation of myeloid leukocyte differentiation Any process that modulates the frequency, rate or extent of macrophage differentiation. http://purl.obolibrary.org/obo/GO_0045650 negative regulation of macrophage differentiation http://purl.obolibrary.org/obo/GO_0045649 regulation of macrophage differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage differentiation. http://purl.obolibrary.org/obo/GO_0045651 positive regulation of macrophage differentiation http://purl.obolibrary.org/obo/GO_0045649 regulation of macrophage differentiation Any process that activates or increases the frequency, rate or extent of macrophage differentiation. http://purl.obolibrary.org/obo/GO_0045664 regulation of neuron differentiation http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the frequency, rate or extent of neuron differentiation. http://purl.obolibrary.org/obo/GO_0045665 negative regulation of neuron differentiation http://purl.obolibrary.org/obo/GO_0045664 regulation of neuron differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of neuron differentiation. http://purl.obolibrary.org/obo/GO_0045666 positive regulation of neuron differentiation http://purl.obolibrary.org/obo/GO_0045664 regulation of neuron differentiation Any process that activates or increases the frequency, rate or extent of neuron differentiation. http://purl.obolibrary.org/obo/GO_0045685 regulation of glial cell differentiation http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the frequency, rate or extent of glia cell differentiation. http://purl.obolibrary.org/obo/GO_0045686 negative regulation of glial cell differentiation http://purl.obolibrary.org/obo/GO_0045685 regulation of glial cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of glia cell differentiation. http://purl.obolibrary.org/obo/GO_0045687 positive regulation of glial cell differentiation http://purl.obolibrary.org/obo/GO_0045685 regulation of glial cell differentiation Any process that activates or increases the frequency, rate or extent of glia cell differentiation. http://purl.obolibrary.org/obo/GO_0045727 positive regulation of translation http://purl.obolibrary.org/obo/GO_0010628 positive regulation of gene expression Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA. http://purl.obolibrary.org/obo/GO_0045765 regulation of angiogenesis http://purl.obolibrary.org/obo/GO_1901342 regulation of vasculature development Any process that modulates the frequency, rate or extent of angiogenesis. http://purl.obolibrary.org/obo/GO_0045785 positive regulation of cell adhesion http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the frequency, rate or extent of cell adhesion. http://purl.obolibrary.org/obo/GO_0045827 negative regulation of isoprenoid metabolic process http://purl.obolibrary.org/obo/GO_0045833 negative regulation of lipid metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving isoprenoid. http://purl.obolibrary.org/obo/GO_0045861 negative regulation of proteolysis http://purl.obolibrary.org/obo/GO_0051248 negative regulation of protein metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein. http://purl.obolibrary.org/obo/GO_0045862 positive regulation of proteolysis http://purl.obolibrary.org/obo/GO_0051247 positive regulation of protein metabolic process Any process that activates or increases the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein. http://purl.obolibrary.org/obo/GO_0045912 negative regulation of carbohydrate metabolic process http://purl.obolibrary.org/obo/GO_0009892 negative regulation of metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving carbohydrate. http://purl.obolibrary.org/obo/GO_0045913 positive regulation of carbohydrate metabolic process http://purl.obolibrary.org/obo/GO_0009893 positive regulation of metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving carbohydrate. http://purl.obolibrary.org/obo/GO_0045934 negative regulation of nucleobase-containing compound metabolic process http://purl.obolibrary.org/obo/GO_0009892 negative regulation of metabolic process Any cellular process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids. http://purl.obolibrary.org/obo/GO_0045936 negative regulation of phosphate metabolic process http://purl.obolibrary.org/obo/GO_0010563 negative regulation of phosphorus metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving phosphates. http://purl.obolibrary.org/obo/GO_0045939 negative regulation of steroid metabolic process http://purl.obolibrary.org/obo/GO_0045833 negative regulation of lipid metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving steroids. http://purl.obolibrary.org/obo/GO_0045940 positive regulation of steroid metabolic process http://purl.obolibrary.org/obo/GO_0045834 positive regulation of lipid metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving steroids. http://purl.obolibrary.org/obo/GO_0045988 negative regulation of striated muscle contraction http://purl.obolibrary.org/obo/GO_0045932 negative regulation of muscle contraction Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle contraction. http://purl.obolibrary.org/obo/GO_0045989 positive regulation of striated muscle contraction http://purl.obolibrary.org/obo/GO_0045933 positive regulation of muscle contraction Any process that activates or increases the frequency, rate or extent of striated muscle contraction. http://purl.obolibrary.org/obo/GO_0046185 aldehyde catabolic process http://purl.obolibrary.org/obo/GO_0009056 catabolic process The chemical reactions and pathways resulting in the breakdown of aldehydes, any organic compound with the formula R-CH=O. http://purl.obolibrary.org/obo/GO_0046395 carboxylic acid catabolic process http://purl.obolibrary.org/obo/GO_0016054 organic acid catabolic process The chemical reactions and pathways resulting in the breakdown of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups. http://purl.obolibrary.org/obo/GO_0046434 organophosphate catabolic process http://purl.obolibrary.org/obo/GO_0009056 catabolic process The chemical reactions and pathways resulting in the breakdown of organophosphates, any phosphate-containing organic compound. http://purl.obolibrary.org/obo/GO_0046545 development of primary female sexual characteristics http://purl.obolibrary.org/obo/GO_0045137 development of primary sexual characteristics The process whose specific outcome is the progression of the primary female sexual characteristics over time, from their formation to the mature structure. The primary female sexual characteristics are the ovaries, and they develop in response to sex hormone secretion. http://purl.obolibrary.org/obo/GO_0046546 development of primary male sexual characteristics http://purl.obolibrary.org/obo/GO_0045137 development of primary sexual characteristics The process whose specific outcome is the progression of the primary male sexual characteristics over time, from their formation to the mature structures. The primary male sexual characteristics are the testes, and they develop in response to sex hormone secretion. http://purl.obolibrary.org/obo/GO_0046624 sphingolipid transporter activity http://purl.obolibrary.org/obo/GO_0005319 lipid transporter activity Enables the directed movement of sphingolipids into, out of or within a cell, or between cells. Sphingolipids are a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid). http://purl.obolibrary.org/obo/GO_0046825 regulation of protein export from nucleus http://purl.obolibrary.org/obo/GO_0046822 regulation of nucleocytoplasmic transport Any process that modulates the frequency, rate or extent of the directed movement of proteins from the nucleus to the cytoplasm. http://purl.obolibrary.org/obo/GO_0046831 regulation of RNA export from nucleus http://purl.obolibrary.org/obo/GO_0046822 regulation of nucleocytoplasmic transport Any process that modulates the frequency, rate or extent of the directed movement of RNA from the nucleus to the cytoplasm. http://purl.obolibrary.org/obo/GO_0046836 glycolipid transport http://purl.obolibrary.org/obo/GO_1901264 carbohydrate derivative transport The directed movement of glycolipids, compounds containing (usually) 1-4 linked monosaccharide residues joined by a glycosyl linkage to a lipid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0046873 metal ion transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0008324 monoatomic cation transmembrane transporter activity Enables the transfer of metal ions from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0046886 positive regulation of hormone biosynthetic process http://purl.obolibrary.org/obo/GO_0009891 positive regulation of biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hormones. http://purl.obolibrary.org/obo/GO_0046889 positive regulation of lipid biosynthetic process http://purl.obolibrary.org/obo/GO_0009891 positive regulation of biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids. http://purl.obolibrary.org/obo/GO_0046929 negative regulation of neurotransmitter secretion http://purl.obolibrary.org/obo/GO_1903531 negative regulation of secretion by cell Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a neurotransmitter. http://purl.obolibrary.org/obo/GO_0048242 epinephrine secretion http://purl.obolibrary.org/obo/GO_0050432 catecholamine secretion The regulated release of epinephrine by a cell. Epinephrine is a catecholamine hormone secreted by the adrenal medulla and a neurotransmitter, released by certain neurons and active in the central nervous system. http://purl.obolibrary.org/obo/GO_0048243 norepinephrine secretion http://purl.obolibrary.org/obo/GO_0050432 catecholamine secretion The regulated release of norepinephrine by a cell. Norepinephrine is a catecholamine and it acts as a hormone and as a neurotransmitter of most of the sympathetic nervous system. http://purl.obolibrary.org/obo/GO_0048246 macrophage chemotaxis http://purl.obolibrary.org/obo/GO_0030595 leukocyte chemotaxis The movement of a macrophage in response to an external stimulus. http://purl.obolibrary.org/obo/GO_0048520 positive regulation of behavior http://purl.obolibrary.org/obo/GO_0050795 regulation of behavior Any process that activates or increases the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli. http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. http://purl.obolibrary.org/obo/GO_0048570 notochord morphogenesis http://purl.obolibrary.org/obo/GO_0048562 embryonic organ morphogenesis The process in which the anatomical structures of the notochord are generated and organized. The notochord is a mesoderm-derived structure located ventral of the developing nerve cord. In vertebrates, the notochord serves as a core around which other mesodermal cells form the vertebrae. In the most primitive chordates, which lack vertebrae, the notochord persists as a substitute for a vertebral column. http://purl.obolibrary.org/obo/GO_0048581 negative regulation of post-embryonic development http://purl.obolibrary.org/obo/GO_0051241 negative regulation of multicellular organismal process Any process that stops, prevents, or reduces the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. http://purl.obolibrary.org/obo/GO_0048582 positive regulation of post-embryonic development http://purl.obolibrary.org/obo/GO_0051240 positive regulation of multicellular organismal process Any process that activates or increases the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. http://purl.obolibrary.org/obo/GO_0048628 myoblast maturation http://purl.obolibrary.org/obo/GO_0048469 cell maturation A developmental process, independent of morphogenetic (shape) change, that is required for a myoblast to attain its fully functional state. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. http://purl.obolibrary.org/obo/GO_0048634 regulation of muscle organ development http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of muscle development. http://purl.obolibrary.org/obo/GO_0048635 negative regulation of muscle organ development http://purl.obolibrary.org/obo/GO_0048634 regulation of muscle organ development Any process that stops, prevents, or reduces the frequency, rate or extent of muscle development. http://purl.obolibrary.org/obo/GO_0048636 positive regulation of muscle organ development http://purl.obolibrary.org/obo/GO_0048634 regulation of muscle organ development Any process that activates, maintains or increases the rate of muscle development. http://purl.obolibrary.org/obo/GO_0048638 regulation of developmental growth http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of developmental growth. http://purl.obolibrary.org/obo/GO_0048641 regulation of skeletal muscle tissue development http://purl.obolibrary.org/obo/GO_0016202 regulation of striated muscle tissue development Any process that modulates the frequency, rate or extent of skeletal muscle tissue development. http://purl.obolibrary.org/obo/GO_0048642 negative regulation of skeletal muscle tissue development http://purl.obolibrary.org/obo/GO_0048641 regulation of skeletal muscle tissue development Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle tissue development. http://purl.obolibrary.org/obo/GO_0048643 positive regulation of skeletal muscle tissue development http://purl.obolibrary.org/obo/GO_0048641 regulation of skeletal muscle tissue development Any process that activates, maintains or increases the rate of skeletal muscle tissue development. http://purl.obolibrary.org/obo/GO_0048708 astrocyte differentiation http://purl.obolibrary.org/obo/GO_0010001 glial cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of an astrocyte. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function. http://purl.obolibrary.org/obo/GO_0048709 oligodendrocyte differentiation http://purl.obolibrary.org/obo/GO_0010001 glial cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of an oligodendrocyte. An oligodendrocyte is a type of glial cell involved in myelinating the axons of neurons in the central nervous system. http://purl.obolibrary.org/obo/GO_0048863 stem cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a stem cell. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells. http://purl.obolibrary.org/obo/GO_0048864 stem cell development http://purl.obolibrary.org/obo/GO_0048468 cell development The process whose specific outcome is the progression of the stem cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to its specific fate. http://purl.obolibrary.org/obo/GO_0048878 chemical homeostasis http://purl.obolibrary.org/obo/GO_0042592 homeostatic process Any biological process involved in the maintenance of an internal steady state of a chemical. http://purl.obolibrary.org/obo/GO_0050432 catecholamine secretion http://purl.obolibrary.org/obo/GO_0051937 catecholamine transport The regulated release of catecholamines by a cell. The catecholamines are a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine. http://purl.obolibrary.org/obo/GO_0050433 regulation of catecholamine secretion http://purl.obolibrary.org/obo/GO_0051952 regulation of amine transport Any process that modulates the frequency, rate or extent of the regulated release of catecholamines. http://purl.obolibrary.org/obo/GO_0050767 regulation of neurogenesis http://purl.obolibrary.org/obo/GO_0060284 regulation of cell development Any process that modulates the frequency, rate or extent of neurogenesis, the generation of cells in the nervous system. http://purl.obolibrary.org/obo/GO_0050790 regulation of catalytic activity http://purl.obolibrary.org/obo/GO_0065009 regulation of molecular function Any process that modulates the activity of an enzyme. http://purl.obolibrary.org/obo/GO_0050810 regulation of steroid biosynthetic process http://purl.obolibrary.org/obo/GO_0046890 regulation of lipid biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus. http://purl.obolibrary.org/obo/GO_0050832 defense response to fungus http://purl.obolibrary.org/obo/GO_0009620 response to fungus Reactions triggered in response to the presence of a fungus that act to protect the cell or organism. http://purl.obolibrary.org/obo/GO_0050848 regulation of calcium-mediated signaling http://purl.obolibrary.org/obo/GO_1902531 regulation of intracellular signal transduction Any process that modulates the frequency, rate or extent of calcium-mediated signaling, the process in which a cell uses calcium ions to convert an extracellular signal into a response. http://purl.obolibrary.org/obo/GO_0050879 multicellular organismal movement http://purl.obolibrary.org/obo/GO_0032501 multicellular organismal process Any physiological process involved in changing the position of a multicellular organism or an anatomical part of a multicellular organism. http://purl.obolibrary.org/obo/GO_0050910 detection of mechanical stimulus involved in sensory perception of sound http://purl.obolibrary.org/obo/GO_0050877 nervous system process The series of events involved in the perception of sound vibration in which the vibration is received and converted into a molecular signal. http://purl.obolibrary.org/obo/GO_0050981 detection of electrical stimulus http://purl.obolibrary.org/obo/GO_0051602 response to electrical stimulus The series of events by which an electrical stimulus is received and converted into a molecular signal. http://purl.obolibrary.org/obo/GO_0050994 regulation of lipid catabolic process http://purl.obolibrary.org/obo/GO_0009894 regulation of catabolic process Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of lipids. http://purl.obolibrary.org/obo/GO_0050995 negative regulation of lipid catabolic process http://purl.obolibrary.org/obo/GO_0050994 regulation of lipid catabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of lipids. http://purl.obolibrary.org/obo/GO_0050996 positive regulation of lipid catabolic process http://purl.obolibrary.org/obo/GO_0050994 regulation of lipid catabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of lipids. http://purl.obolibrary.org/obo/GO_0051027 DNA transport http://purl.obolibrary.org/obo/GO_0050657 nucleic acid transport The directed movement of RNA, deoxyribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0051035 DNA transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0051032 nucleic acid transmembrane transporter activity Enables the transfer of DNA, deoxyribonucleic acid, from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0051049 regulation of transport http://purl.obolibrary.org/obo/GO_0032879 regulation of localization Any process that modulates the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0051050 positive regulation of transport http://purl.obolibrary.org/obo/GO_0051049 regulation of transport Any process that activates or increases the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0051051 negative regulation of transport http://purl.obolibrary.org/obo/GO_0051049 regulation of transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0051055 negative regulation of lipid biosynthetic process http://purl.obolibrary.org/obo/GO_0009890 negative regulation of biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids. http://purl.obolibrary.org/obo/GO_0051129 negative regulation of cellular component organization http://purl.obolibrary.org/obo/GO_0051128 regulation of cellular component organization Any process that stops, prevents, or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope. http://purl.obolibrary.org/obo/GO_0051130 positive regulation of cellular component organization http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope. http://purl.obolibrary.org/obo/GO_0051146 striated muscle cell differentiation http://purl.obolibrary.org/obo/GO_0042692 muscle cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a striated muscle cell; striated muscle fibers are divided by transverse bands into striations, and cardiac and voluntary muscle are types of striated muscle. http://purl.obolibrary.org/obo/GO_0051153 regulation of striated muscle cell differentiation http://purl.obolibrary.org/obo/GO_0051147 regulation of muscle cell differentiation Any process that modulates the frequency, rate or extent of striated muscle cell differentiation. http://purl.obolibrary.org/obo/GO_0051154 negative regulation of striated muscle cell differentiation http://purl.obolibrary.org/obo/GO_0051153 regulation of striated muscle cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle cell differentiation. http://purl.obolibrary.org/obo/GO_0051155 positive regulation of striated muscle cell differentiation http://purl.obolibrary.org/obo/GO_0051153 regulation of striated muscle cell differentiation Any process that activates or increases the frequency, rate or extent of striated muscle cell differentiation. http://purl.obolibrary.org/obo/GO_0051174 regulation of phosphorus metabolic process http://purl.obolibrary.org/obo/GO_0019222 regulation of metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus. http://purl.obolibrary.org/obo/GO_0051209 release of sequestered calcium ion into cytosol http://purl.obolibrary.org/obo/GO_0097553 calcium ion transmembrane import into cytosol The process in which calcium ions sequestered in the endoplasmic reticulum, Golgi apparatus or mitochondria are released into the cytosolic compartment. http://purl.obolibrary.org/obo/GO_0051279 regulation of release of sequestered calcium ion into cytosol http://purl.obolibrary.org/obo/GO_1903169 regulation of calcium ion transmembrane transport Any process that modulates the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria. http://purl.obolibrary.org/obo/GO_0051336 regulation of hydrolase activity http://purl.obolibrary.org/obo/GO_0050790 regulation of catalytic activity Any process that modulates the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3. http://purl.obolibrary.org/obo/GO_0051345 positive regulation of hydrolase activity http://purl.obolibrary.org/obo/GO_0051336 regulation of hydrolase activity Any process that activates or increases the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds. http://purl.obolibrary.org/obo/GO_0051346 negative regulation of hydrolase activity http://purl.obolibrary.org/obo/GO_0051336 regulation of hydrolase activity Any process that stops or reduces the rate of hydrolase activity, the catalysis of the hydrolysis of various bonds. http://purl.obolibrary.org/obo/GO_0051450 myoblast proliferation http://purl.obolibrary.org/obo/GO_0008283 cell population proliferation The multiplication or reproduction of myoblasts, resulting in the expansion of a myoblast cell population. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. http://purl.obolibrary.org/obo/GO_0051451 myoblast migration http://purl.obolibrary.org/obo/GO_0014812 muscle cell migration The orderly movement of a myoblast from one site to another, often during the development of a multicellular organism. A myoblast is a cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. http://purl.obolibrary.org/obo/GO_0051494 negative regulation of cytoskeleton organization http://purl.obolibrary.org/obo/GO_0010639 negative regulation of organelle organization Any process that stops, prevents, or reduces the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures. http://purl.obolibrary.org/obo/GO_0051495 positive regulation of cytoskeleton organization http://purl.obolibrary.org/obo/GO_0010638 positive regulation of organelle organization Any process that activates or increases the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures. http://purl.obolibrary.org/obo/GO_0051602 response to electrical stimulus http://purl.obolibrary.org/obo/GO_0009628 response to abiotic stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus. http://purl.obolibrary.org/obo/GO_0051606 detection of stimulus http://purl.obolibrary.org/obo/GO_0050896 response to stimulus The series of events in which a stimulus is received by a cell or organism and converted into a molecular signal. http://purl.obolibrary.org/obo/GO_0051640 organelle localization http://purl.obolibrary.org/obo/GO_0051179 localization Any process in which an organelle is transported to, and/or maintained in, a specific location. http://purl.obolibrary.org/obo/GO_0051667 establishment of plastid localization http://purl.obolibrary.org/obo/GO_0051656 establishment of organelle localization The directed movement of a plastid to a specific location in the cell. http://purl.obolibrary.org/obo/GO_0051881 regulation of mitochondrial membrane potential http://purl.obolibrary.org/obo/GO_0042391 regulation of membrane potential Any process that modulates the establishment or extent of the mitochondrial membrane potential, the electric potential existing across the mitochondrial membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane. http://purl.obolibrary.org/obo/GO_0051892 negative regulation of cardioblast differentiation http://purl.obolibrary.org/obo/GO_0051890 regulation of cardioblast differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. http://purl.obolibrary.org/obo/GO_0051924 regulation of calcium ion transport http://purl.obolibrary.org/obo/GO_0010959 regulation of metal ion transport Any process that modulates the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0051926 negative regulation of calcium ion transport http://purl.obolibrary.org/obo/GO_0051924 regulation of calcium ion transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0051928 positive regulation of calcium ion transport http://purl.obolibrary.org/obo/GO_0051924 regulation of calcium ion transport Any process that activates or increases the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0051937 catecholamine transport http://purl.obolibrary.org/obo/GO_0015850 organic hydroxy compound transport The directed movement of catecholamines, a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine. http://purl.obolibrary.org/obo/GO_0051952 regulation of amine transport http://purl.obolibrary.org/obo/GO_0051049 regulation of transport Any process that modulates the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0051953 negative regulation of amine transport http://purl.obolibrary.org/obo/GO_0051952 regulation of amine transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0051954 positive regulation of amine transport http://purl.obolibrary.org/obo/GO_0051952 regulation of amine transport Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0051963 regulation of synapse assembly http://purl.obolibrary.org/obo/GO_1901888 regulation of cell junction assembly Any process that modulates the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse. http://purl.obolibrary.org/obo/GO_0055002 striated muscle cell development http://purl.obolibrary.org/obo/GO_0055001 muscle cell development The process whose specific outcome is the progression of a striated muscle cell over time, from its formation to the mature structure. Striated muscle cells contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle. http://purl.obolibrary.org/obo/GO_0055088 lipid homeostasis http://purl.obolibrary.org/obo/GO_0048878 chemical homeostasis Any process involved in the maintenance of an internal steady state of lipid within an organism or cell. http://purl.obolibrary.org/obo/GO_0055117 regulation of cardiac muscle contraction http://purl.obolibrary.org/obo/GO_0008016 regulation of heart contraction Any process that modulates the frequency, rate or extent of cardiac muscle contraction. http://purl.obolibrary.org/obo/GO_0060042 retina morphogenesis in camera-type eye http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structure of the retina is generated and organized. http://purl.obolibrary.org/obo/GO_0060048 cardiac muscle contraction http://purl.obolibrary.org/obo/GO_0006941 striated muscle contraction Muscle contraction of cardiac muscle tissue. http://purl.obolibrary.org/obo/GO_0060251 regulation of glial cell proliferation http://purl.obolibrary.org/obo/GO_0042127 regulation of cell population proliferation Any process that modulates the frequency, rate or extent of glial cell proliferation. http://purl.obolibrary.org/obo/GO_0060252 positive regulation of glial cell proliferation http://purl.obolibrary.org/obo/GO_0060251 regulation of glial cell proliferation Any process that activates or increases the rate or extent of glial cell proliferation. http://purl.obolibrary.org/obo/GO_0060253 negative regulation of glial cell proliferation http://purl.obolibrary.org/obo/GO_0060251 regulation of glial cell proliferation Any process that stops or decreases the rate or extent of glial cell proliferation. http://purl.obolibrary.org/obo/GO_0060284 regulation of cell development http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. http://purl.obolibrary.org/obo/GO_0060319 primitive erythrocyte differentiation http://purl.obolibrary.org/obo/GO_0030218 erythrocyte differentiation Erythrocyte differentiation which occurs as part of the process of primitive hemopoiesis. http://purl.obolibrary.org/obo/GO_0060341 regulation of cellular localization http://purl.obolibrary.org/obo/GO_0032879 regulation of localization Any process that modulates the frequency, rate or extent of a process in which a cell, a substance, or a cellular entity is transported to, or maintained in a specific location within or in the membrane of a cell. http://purl.obolibrary.org/obo/GO_0060491 regulation of cell projection assembly http://purl.obolibrary.org/obo/GO_0031344 regulation of cell projection organization Any process that modulates the rate, frequency, or extent of cell projection assembly. http://purl.obolibrary.org/obo/GO_0060537 muscle tissue development http://purl.obolibrary.org/obo/GO_0009888 tissue development The progression of muscle tissue over time, from its initial formation to its mature state. Muscle tissue is a contractile tissue made up of actin and myosin fibers. http://purl.obolibrary.org/obo/GO_0060627 regulation of vesicle-mediated transport http://purl.obolibrary.org/obo/GO_0051049 regulation of transport Any process that modulates the rate, frequency, or extent of vesicle-mediated transport, the directed movement of substances, either within a vesicle or in the vesicle membrane, into, out of or within a cell. http://purl.obolibrary.org/obo/GO_0061515 myeloid cell development http://purl.obolibrary.org/obo/GO_0030097 hemopoiesis The process whose specific outcome is the progression of a myeloid cell over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0061526 acetylcholine secretion http://purl.obolibrary.org/obo/GO_0015870 acetylcholine transport The regulated release of acetylcholine by a cell. http://purl.obolibrary.org/obo/GO_0061687 detoxification of inorganic compound http://purl.obolibrary.org/obo/GO_0098754 detoxification Any process that reduces or removes the toxicity of inorganic compounds. These include transport of such compounds away from sensitive areas and to compartments or complexes whose purpose is sequestration of inorganic compounds. http://purl.obolibrary.org/obo/GO_0065009 regulation of molecular function http://purl.obolibrary.org/obo/GO_0065007 biological regulation Any process that modulates the frequency, rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding. http://purl.obolibrary.org/obo/GO_0070131 positive regulation of mitochondrial translation http://purl.obolibrary.org/obo/GO_0070129 regulation of mitochondrial translation Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion. http://purl.obolibrary.org/obo/GO_0070507 regulation of microtubule cytoskeleton organization http://purl.obolibrary.org/obo/GO_0032886 regulation of microtubule-based process Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins. http://purl.obolibrary.org/obo/GO_0070613 regulation of protein processing http://purl.obolibrary.org/obo/GO_1903317 regulation of protein maturation Any process that modulates the frequency, rate or extent of protein processing, a protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein. http://purl.obolibrary.org/obo/GO_0071322 cellular response to carbohydrate stimulus http://purl.obolibrary.org/obo/GO_0009743 response to carbohydrate Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbohydrate stimulus. http://purl.obolibrary.org/obo/GO_0071331 cellular response to hexose stimulus http://purl.obolibrary.org/obo/GO_0071326 cellular response to monosaccharide stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hexose stimulus. http://purl.obolibrary.org/obo/GO_0071333 cellular response to glucose stimulus http://purl.obolibrary.org/obo/GO_0071331 cellular response to hexose stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus. http://purl.obolibrary.org/obo/GO_0071622 regulation of granulocyte chemotaxis http://purl.obolibrary.org/obo/GO_0002688 regulation of leukocyte chemotaxis Any process that modulates the rate, frequency or extent of granulocyte chemotaxis. Granulocyte chemotaxis is the movement of a granulocyte in response to an external stimulus. http://purl.obolibrary.org/obo/GO_0071675 regulation of mononuclear cell migration http://purl.obolibrary.org/obo/GO_0002685 regulation of leukocyte migration Any process that modulates the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body. http://purl.obolibrary.org/obo/GO_0071806 protein transmembrane transport http://purl.obolibrary.org/obo/GO_0055085 transmembrane transport The process in which a protein is transported across a membrane. http://purl.obolibrary.org/obo/GO_0071840 cellular component organization or biogenesis http://purl.obolibrary.org/obo/GO_0009987 cellular process A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellular component. http://purl.obolibrary.org/obo/GO_0071941 nitrogen cycle metabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process A nitrogen compound metabolic process that contributes to the nitrogen cycle. The nitrogen cycle is a series of metabolic pathways by which nitrogen is converted between various forms and redox states; it encompasses pathways in which nitrogen is acted upon directly, such as nitrification, denitrification, nitrogen fixation, and mineralization. http://purl.obolibrary.org/obo/GO_0072337 modified amino acid transport http://purl.obolibrary.org/obo/GO_0071705 nitrogen compound transport The directed movement of modified amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0072488 ammonium transmembrane transport http://purl.obolibrary.org/obo/GO_0071705 nitrogen compound transport The process in which ammonium is transported across a membrane. Ammonium is the cation NH4+. http://purl.obolibrary.org/obo/GO_0072530 purine-containing compound transmembrane transport http://purl.obolibrary.org/obo/GO_0071705 nitrogen compound transport The process in which a purine-containing compound is transported across a membrane. A purine-containing compound is any compound that contains purine or a formal derivative thereof. http://purl.obolibrary.org/obo/GO_0072678 T cell migration http://purl.obolibrary.org/obo/GO_0072676 lymphocyte migration The movement of a T cell within or between different tissues and organs of the body. http://purl.obolibrary.org/obo/GO_0080134 regulation of response to stress http://purl.obolibrary.org/obo/GO_0048583 regulation of response to stimulus Any process that modulates the frequency, rate or extent of a response to stress. Response to stress is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). http://purl.obolibrary.org/obo/GO_0085029 extracellular matrix assembly http://purl.obolibrary.org/obo/GO_0030198 extracellular matrix organization The aggregation, arrangement and bonding together of the extracellular matrix. http://purl.obolibrary.org/obo/GO_0090032 negative regulation of steroid hormone biosynthetic process http://purl.obolibrary.org/obo/GO_0010894 negative regulation of steroid biosynthetic process Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroid hormones,compounds with a 1, 2, cyclopentanoperhydrophenanthrene nucleus that act as hormones. http://purl.obolibrary.org/obo/GO_0090068 positive regulation of cell cycle process http://purl.obolibrary.org/obo/GO_0045787 positive regulation of cell cycle Any process that increases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. http://purl.obolibrary.org/obo/GO_0090077 foam cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions. http://purl.obolibrary.org/obo/GO_0090132 epithelium migration http://purl.obolibrary.org/obo/GO_0090130 tissue migration The process in which the population of cells that make up an epithelium undergo directed movement. http://purl.obolibrary.org/obo/GO_0097305 response to alcohol http://purl.obolibrary.org/obo/GO_1901700 response to oxygen-containing compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alcohol stimulus. http://purl.obolibrary.org/obo/GO_0098590 plasma membrane region http://purl.obolibrary.org/obo/GO_0016020 membrane A membrane that is a (regional) part of the plasma membrane. http://purl.obolibrary.org/obo/GO_0098609 cell-cell adhesion http://purl.obolibrary.org/obo/GO_0007155 cell adhesion The attachment of one cell to another cell via adhesion molecules. http://purl.obolibrary.org/obo/GO_0098636 protein complex involved in cell adhesion http://purl.obolibrary.org/obo/GO_0032991 protein-containing complex Any protein complex that is capable of carrying out some part of the process of cell adhesion to the cell matrix or to another cell. http://purl.obolibrary.org/obo/GO_0098655 monoatomic cation transmembrane transport http://purl.obolibrary.org/obo/GO_0034220 monoatomic ion transmembrane transport The process in which a monoatomic cation is transported across a membrane. Monatomic cations (also called simple cations) are positively charged ions consisting of exactly one atom. http://purl.obolibrary.org/obo/GO_0098722 asymmetric stem cell division http://purl.obolibrary.org/obo/GO_0017145 stem cell division Division of a stem cell during which it retains its identity and buds off a daughter cell with a new identity. http://purl.obolibrary.org/obo/GO_0098727 maintenance of cell number http://purl.obolibrary.org/obo/GO_0032502 developmental process Any process by which the numbers of cells of a particular type or in a tissue are maintained. http://purl.obolibrary.org/obo/GO_0098754 detoxification http://purl.obolibrary.org/obo/GO_0008150 biological_process Any process that reduces or removes the toxicity of a toxic substance. These may include transport of the toxic substance away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance. http://purl.obolibrary.org/obo/GO_0098815 modulation of excitatory postsynaptic potential http://purl.obolibrary.org/obo/GO_0050804 modulation of chemical synaptic transmission Any process that modulates the frequency, rate or extent of excitatory postsynaptic potential (EPSP). EPSP is a process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential. http://purl.obolibrary.org/obo/GO_0098878 neurotransmitter receptor complex http://purl.obolibrary.org/obo/GO_0098802 plasma membrane signaling receptor complex Any protein complex that is capable of functioning as a neurotransmitter receptor. http://purl.obolibrary.org/obo/GO_0098900 regulation of action potential http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels. http://purl.obolibrary.org/obo/GO_0099003 vesicle-mediated transport in synapse http://purl.obolibrary.org/obo/GO_0016192 vesicle-mediated transport Any vesicle-mediated transport that occurs in a synapse. http://purl.obolibrary.org/obo/GO_0099111 microtubule-based transport http://purl.obolibrary.org/obo/GO_0006810 transport A microtubule-based process that results in the transport of organelles, other microtubules, or other cellular components. Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules. http://purl.obolibrary.org/obo/GO_0099504 synaptic vesicle cycle http://purl.obolibrary.org/obo/GO_0099003 vesicle-mediated transport in synapse A biological process in which synaptic vesicles are loaded with neurotransmitters, move to the active zone, exocytose and are then recycled via endocytosis, ultimately leading to reloading with neurotransmitters. http://purl.obolibrary.org/obo/GO_0099528 G protein-coupled neurotransmitter receptor activity http://purl.obolibrary.org/obo/GO_0004930 G protein-coupled receptor activity Combining with a neurotransmitter and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. http://purl.obolibrary.org/obo/GO_0099604 ligand-gated calcium channel activity http://purl.obolibrary.org/obo/GO_0099094 ligand-gated monoatomic cation channel activity Enables the transmembrane transfer of a calcium ions by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts. http://purl.obolibrary.org/obo/GO_0100001 regulation of skeletal muscle contraction by action potential http://purl.obolibrary.org/obo/GO_0014819 regulation of skeletal muscle contraction Any action potential process that regulates skeletal muscle contraction. http://purl.obolibrary.org/obo/GO_1901264 carbohydrate derivative transport http://purl.obolibrary.org/obo/GO_0006810 transport The directed movement of a carbohydrate derivative into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_1901292 nucleoside phosphate catabolic process http://purl.obolibrary.org/obo/GO_0046434 organophosphate catabolic process The chemical reactions and pathways resulting in the breakdown of a nucleoside phosphate. http://purl.obolibrary.org/obo/GO_1901293 nucleoside phosphate biosynthetic process http://purl.obolibrary.org/obo/GO_0034654 nucleobase-containing compound biosynthetic process The chemical reactions and pathways resulting in the formation of a nucleoside phosphate. http://purl.obolibrary.org/obo/GO_1901374 acetate ester transport http://purl.obolibrary.org/obo/GO_0006810 transport The directed movement of an acetate ester into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_1901385 regulation of voltage-gated calcium channel activity http://purl.obolibrary.org/obo/GO_0022898 regulation of transmembrane transporter activity Any process that modulates the frequency, rate or extent of voltage-gated calcium channel activity. http://purl.obolibrary.org/obo/GO_1901419 regulation of response to alcohol http://purl.obolibrary.org/obo/GO_0048583 regulation of response to stimulus Any process that modulates the frequency, rate or extent of response to alcohol. http://purl.obolibrary.org/obo/GO_1901420 negative regulation of response to alcohol http://purl.obolibrary.org/obo/GO_1901419 regulation of response to alcohol Any process that stops, prevents or reduces the frequency, rate or extent of response to alcohol. http://purl.obolibrary.org/obo/GO_1901421 positive regulation of response to alcohol http://purl.obolibrary.org/obo/GO_1901419 regulation of response to alcohol Any process that activates or increases the frequency, rate or extent of response to alcohol. http://purl.obolibrary.org/obo/GO_1901623 regulation of lymphocyte chemotaxis http://purl.obolibrary.org/obo/GO_2000401 regulation of lymphocyte migration Any process that modulates the frequency, rate or extent of lymphocyte chemotaxis. http://purl.obolibrary.org/obo/GO_1901679 nucleotide transmembrane transport http://purl.obolibrary.org/obo/GO_0055085 transmembrane transport The directed movement of nucleotide across a membrane. http://purl.obolibrary.org/obo/GO_1901698 response to nitrogen compound http://purl.obolibrary.org/obo/GO_0042221 response to chemical Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen compound stimulus. http://purl.obolibrary.org/obo/GO_1901861 regulation of muscle tissue development http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of muscle tissue development. http://purl.obolibrary.org/obo/GO_1902115 regulation of organelle assembly http://purl.obolibrary.org/obo/GO_0033043 regulation of organelle organization Any process that modulates the frequency, rate or extent of organelle assembly. http://purl.obolibrary.org/obo/GO_1902116 negative regulation of organelle assembly http://purl.obolibrary.org/obo/GO_1902115 regulation of organelle assembly Any process that stops, prevents or reduces the frequency, rate or extent of organelle assembly. http://purl.obolibrary.org/obo/GO_1902117 positive regulation of organelle assembly http://purl.obolibrary.org/obo/GO_1902115 regulation of organelle assembly Any process that activates or increases the frequency, rate or extent of organelle assembly. http://purl.obolibrary.org/obo/GO_1902475 L-alpha-amino acid transmembrane transport http://purl.obolibrary.org/obo/GO_0015807 L-amino acid transport The directed movement of L-alpha-amino acid across a membrane by means of some agent such as a transporter or a pore. http://purl.obolibrary.org/obo/GO_1902495 transmembrane transporter complex http://purl.obolibrary.org/obo/GO_1990351 transporter complex A transmembrane protein complex which enables the transfer of a substance from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_1902531 regulation of intracellular signal transduction http://purl.obolibrary.org/obo/GO_0009966 regulation of signal transduction Any process that modulates the frequency, rate or extent of intracellular signal transduction. http://purl.obolibrary.org/obo/GO_1902532 negative regulation of intracellular signal transduction http://purl.obolibrary.org/obo/GO_1902531 regulation of intracellular signal transduction Any process that stops, prevents or reduces the frequency, rate or extent of intracellular signal transduction. http://purl.obolibrary.org/obo/GO_1902533 positive regulation of intracellular signal transduction http://purl.obolibrary.org/obo/GO_1902531 regulation of intracellular signal transduction Any process that activates or increases the frequency, rate or extent of intracellular signal transduction. http://purl.obolibrary.org/obo/GO_1902600 proton transmembrane transport http://purl.obolibrary.org/obo/GO_0098655 monoatomic cation transmembrane transport The directed movement of a proton across a membrane. http://purl.obolibrary.org/obo/GO_1902730 positive regulation of proteoglycan biosynthetic process http://purl.obolibrary.org/obo/GO_0010560 positive regulation of glycoprotein biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans. http://purl.obolibrary.org/obo/GO_1902930 regulation of alcohol biosynthetic process http://purl.obolibrary.org/obo/GO_0009889 regulation of biosynthetic process Any process that modulates the frequency, rate or extent of alcohol biosynthetic process. http://purl.obolibrary.org/obo/GO_1902931 negative regulation of alcohol biosynthetic process http://purl.obolibrary.org/obo/GO_1902930 regulation of alcohol biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of alcohol biosynthetic process. http://purl.obolibrary.org/obo/GO_1902932 positive regulation of alcohol biosynthetic process http://purl.obolibrary.org/obo/GO_1902930 regulation of alcohol biosynthetic process Any process that activates or increases the frequency, rate or extent of alcohol biosynthetic process. http://purl.obolibrary.org/obo/GO_1903018 regulation of glycoprotein metabolic process http://purl.obolibrary.org/obo/GO_0051246 regulation of protein metabolic process Any process that modulates the frequency, rate or extent of glycoprotein metabolic process. http://purl.obolibrary.org/obo/GO_1903019 negative regulation of glycoprotein metabolic process http://purl.obolibrary.org/obo/GO_1903018 regulation of glycoprotein metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of glycoprotein metabolic process. http://purl.obolibrary.org/obo/GO_1903020 positive regulation of glycoprotein metabolic process http://purl.obolibrary.org/obo/GO_1903018 regulation of glycoprotein metabolic process Any process that activates or increases the frequency, rate or extent of glycoprotein metabolic process. http://purl.obolibrary.org/obo/GO_1903305 regulation of regulated secretory pathway http://purl.obolibrary.org/obo/GO_0017157 regulation of exocytosis Any process that modulates the frequency, rate or extent of regulated secretory pathway. http://purl.obolibrary.org/obo/GO_1903318 negative regulation of protein maturation http://purl.obolibrary.org/obo/GO_1903317 regulation of protein maturation Any process that stops, prevents or reduces the frequency, rate or extent of protein maturation. http://purl.obolibrary.org/obo/GO_1903319 positive regulation of protein maturation http://purl.obolibrary.org/obo/GO_1903317 regulation of protein maturation Any process that activates or increases the frequency, rate or extent of protein maturation. http://purl.obolibrary.org/obo/GO_1903426 regulation of reactive oxygen species biosynthetic process http://purl.obolibrary.org/obo/GO_2000377 regulation of reactive oxygen species metabolic process Any process that modulates the frequency, rate or extent of reactive oxygen species biosynthetic process. http://purl.obolibrary.org/obo/GO_1903427 negative regulation of reactive oxygen species biosynthetic process http://purl.obolibrary.org/obo/GO_2000378 negative regulation of reactive oxygen species metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of reactive oxygen species biosynthetic process. http://purl.obolibrary.org/obo/GO_1903428 positive regulation of reactive oxygen species biosynthetic process http://purl.obolibrary.org/obo/GO_2000379 positive regulation of reactive oxygen species metabolic process Any process that activates or increases the frequency, rate or extent of reactive oxygen species biosynthetic process. http://purl.obolibrary.org/obo/GO_1903430 negative regulation of cell maturation http://purl.obolibrary.org/obo/GO_0010721 negative regulation of cell development Any process that stops, prevents or reduces the frequency, rate or extent of cell maturation. http://purl.obolibrary.org/obo/GO_1903431 positive regulation of cell maturation http://purl.obolibrary.org/obo/GO_0010720 positive regulation of cell development Any process that activates or increases the frequency, rate or extent of cell maturation. http://purl.obolibrary.org/obo/GO_1903828 negative regulation of protein localization http://purl.obolibrary.org/obo/GO_0032880 regulation of protein localization Any process that stops, prevents or reduces the frequency, rate or extent of a protein localization. http://purl.obolibrary.org/obo/GO_1904062 regulation of monoatomic cation transmembrane transport http://purl.obolibrary.org/obo/GO_0034765 regulation of monoatomic ion transmembrane transport Any process that modulates the frequency, rate or extent of cation transmembrane transport. http://purl.obolibrary.org/obo/GO_1904396 regulation of neuromuscular junction development http://purl.obolibrary.org/obo/GO_0050807 regulation of synapse organization Any process that modulates the frequency, rate or extent of neuromuscular junction development. http://purl.obolibrary.org/obo/GO_1904680 peptide transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity Enables the transfer of a peptide from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_1904949 ATPase complex http://purl.obolibrary.org/obo/GO_1902494 catalytic complex A protein complex which is capable of ATPase activity. http://purl.obolibrary.org/obo/GO_1905521 regulation of macrophage migration http://purl.obolibrary.org/obo/GO_0071675 regulation of mononuclear cell migration Any process that modulates the frequency, rate or extent of macrophage migration. http://purl.obolibrary.org/obo/GO_1905522 negative regulation of macrophage migration http://purl.obolibrary.org/obo/GO_0071676 negative regulation of mononuclear cell migration Any process that stops, prevents or reduces the frequency, rate or extent of macrophage migration. http://purl.obolibrary.org/obo/GO_1905523 positive regulation of macrophage migration http://purl.obolibrary.org/obo/GO_0071677 positive regulation of mononuclear cell migration Any process that activates or increases the frequency, rate or extent of macrophage migration. http://purl.obolibrary.org/obo/GO_1990822 basic amino acid transmembrane transport http://purl.obolibrary.org/obo/GO_0015802 basic amino acid transport The directed movement of basic amino acids from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_2000181 negative regulation of blood vessel morphogenesis http://purl.obolibrary.org/obo/GO_1901343 negative regulation of vasculature development Any process that stops, prevents, or reduces the frequency, rate or extent of blood vessel morphogenesis. http://purl.obolibrary.org/obo/GO_2000191 regulation of fatty acid transport http://purl.obolibrary.org/obo/GO_0032890 regulation of organic acid transport Any process that modulates the frequency, rate or extent of fatty acid transport. http://purl.obolibrary.org/obo/GO_2000192 negative regulation of fatty acid transport http://purl.obolibrary.org/obo/GO_2000191 regulation of fatty acid transport Any process that stops, prevents, or reduces the frequency, rate or extent of fatty acid transport. http://purl.obolibrary.org/obo/GO_2000193 positive regulation of fatty acid transport http://purl.obolibrary.org/obo/GO_2000191 regulation of fatty acid transport Any process that activates or increases the frequency, rate or extent of fatty acid transport. http://purl.obolibrary.org/obo/GO_2000197 regulation of ribonucleoprotein complex localization http://purl.obolibrary.org/obo/GO_0060341 regulation of cellular localization Any process that modulates the frequency, rate or extent of ribonucleoprotein complex localization. http://purl.obolibrary.org/obo/GO_2000241 regulation of reproductive process http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process Any process that modulates the frequency, rate or extent of reproductive process. http://purl.obolibrary.org/obo/GO_2000242 negative regulation of reproductive process http://purl.obolibrary.org/obo/GO_2000241 regulation of reproductive process Any process that stops, prevents, or reduces the frequency, rate or extent of reproductive process. http://purl.obolibrary.org/obo/GO_2000243 positive regulation of reproductive process http://purl.obolibrary.org/obo/GO_2000241 regulation of reproductive process Any process that activates or increases the frequency, rate or extent of reproductive process. http://purl.obolibrary.org/obo/GO_2000300 regulation of synaptic vesicle exocytosis http://purl.obolibrary.org/obo/GO_1903305 regulation of regulated secretory pathway Any process that modulates the frequency, rate or extent of synaptic vesicle exocytosis. http://purl.obolibrary.org/obo/GO_2000301 negative regulation of synaptic vesicle exocytosis http://purl.obolibrary.org/obo/GO_2000300 regulation of synaptic vesicle exocytosis Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle exocytosis. http://purl.obolibrary.org/obo/GO_2000302 positive regulation of synaptic vesicle exocytosis http://purl.obolibrary.org/obo/GO_2000300 regulation of synaptic vesicle exocytosis Any process that activates or increases the frequency, rate or extent of synaptic vesicle exocytosis. http://purl.obolibrary.org/obo/GO_2000377 regulation of reactive oxygen species metabolic process http://purl.obolibrary.org/obo/GO_0019222 regulation of metabolic process Any process that modulates the frequency, rate or extent of reactive oxygen species metabolic process. http://purl.obolibrary.org/obo/GO_2000378 negative regulation of reactive oxygen species metabolic process http://purl.obolibrary.org/obo/GO_2000377 regulation of reactive oxygen species metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of reactive oxygen species metabolic process. http://purl.obolibrary.org/obo/GO_2000379 positive regulation of reactive oxygen species metabolic process http://purl.obolibrary.org/obo/GO_2000377 regulation of reactive oxygen species metabolic process Any process that activates or increases the frequency, rate or extent of reactive oxygen species metabolic process. http://purl.obolibrary.org/obo/GO_2000404 regulation of T cell migration http://purl.obolibrary.org/obo/GO_2000401 regulation of lymphocyte migration Any process that modulates the frequency, rate or extent of T cell migration. http://purl.obolibrary.org/obo/GO_2000406 positive regulation of T cell migration http://purl.obolibrary.org/obo/GO_2000404 regulation of T cell migration Any process that activates or increases the frequency, rate or extent of T cell migration. http://purl.obolibrary.org/obo/GO_2000904 regulation of starch metabolic process http://purl.obolibrary.org/obo/GO_0032881 regulation of polysaccharide metabolic process Any process that modulates the frequency, rate or extent of starch metabolic process. http://purl.obolibrary.org/obo/GO_0051938 L-glutamate import http://purl.obolibrary.org/obo/GO_0015807 L-amino acid transport The directed movement of L-glutamate, the L-enantiomer of the anion of 2-aminopentanedioic acid, into a cell or organelle. http://purl.obolibrary.org/obo/GO_0051966 regulation of synaptic transmission, glutamatergic http://purl.obolibrary.org/obo/GO_0050804 modulation of chemical synaptic transmission Any process that modulates the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate. http://purl.obolibrary.org/obo/GO_0051967 negative regulation of synaptic transmission, glutamatergic http://purl.obolibrary.org/obo/GO_0051966 regulation of synaptic transmission, glutamatergic Any process that stops, prevents, or reduces the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate. http://purl.obolibrary.org/obo/GO_0051968 positive regulation of synaptic transmission, glutamatergic http://purl.obolibrary.org/obo/GO_0051966 regulation of synaptic transmission, glutamatergic Any process that activates, maintains or increases the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate. http://purl.obolibrary.org/obo/GO_0051970 negative regulation of transmission of nerve impulse http://purl.obolibrary.org/obo/GO_0010648 negative regulation of cell communication Any process that stops, prevents, or reduces the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation. http://purl.obolibrary.org/obo/GO_0051971 positive regulation of transmission of nerve impulse http://purl.obolibrary.org/obo/GO_0010647 positive regulation of cell communication Any process that activates, maintains or increases the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation. http://purl.obolibrary.org/obo/GO_0055003 cardiac myofibril assembly http://purl.obolibrary.org/obo/GO_0030239 myofibril assembly The process whose specific outcome is the progression of the cardiac myofibril over time, from its formation to the mature structure. A cardiac myofibril is a myofibril specific to cardiac muscle cells. http://purl.obolibrary.org/obo/GO_0055006 cardiac cell development http://purl.obolibrary.org/obo/GO_0048468 cell development The process whose specific outcome is the progression of a cardiac cell over time, from its formation to the mature state. A cardiac cell is a cell that will form part of the cardiac organ of an individual. http://purl.obolibrary.org/obo/GO_0055007 cardiac muscle cell differentiation http://purl.obolibrary.org/obo/GO_0051146 striated muscle cell differentiation The process in which a cardiac muscle precursor cell acquires specialized features of a cardiac muscle cell. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. http://purl.obolibrary.org/obo/GO_0055009 atrial cardiac muscle tissue morphogenesis http://purl.obolibrary.org/obo/GO_0055008 cardiac muscle tissue morphogenesis The process in which the anatomical structure of cardiac atrium muscle is generated and organized. http://purl.obolibrary.org/obo/GO_0055011 atrial cardiac muscle cell differentiation http://purl.obolibrary.org/obo/GO_0055007 cardiac muscle cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a cardiac muscle cell in the atrium. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. The atrium is the part of the heart that receives blood into the organ. http://purl.obolibrary.org/obo/GO_0055014 atrial cardiac muscle cell development http://purl.obolibrary.org/obo/GO_0055013 cardiac muscle cell development The process whose specific outcome is the progression of an atrial cardiac muscle cell over time, from its formation to the mature state. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. The atrium is the part of the heart that receives blood into the organ. http://purl.obolibrary.org/obo/GO_0055018 regulation of cardiac muscle fiber development http://purl.obolibrary.org/obo/GO_2000725 regulation of cardiac muscle cell differentiation Any process that modulates the frequency, rate or extent of cardiac muscle fiber development. http://purl.obolibrary.org/obo/GO_0055019 negative regulation of cardiac muscle fiber development http://purl.obolibrary.org/obo/GO_0055018 regulation of cardiac muscle fiber development Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle fiber development. http://purl.obolibrary.org/obo/GO_0055020 positive regulation of cardiac muscle fiber development http://purl.obolibrary.org/obo/GO_2000727 positive regulation of cardiac muscle cell differentiation Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle fiber development. http://purl.obolibrary.org/obo/GO_0055021 regulation of cardiac muscle tissue growth http://purl.obolibrary.org/obo/GO_0060420 regulation of heart growth Any process that modulates the frequency, rate or extent of cardiac muscle growth. http://purl.obolibrary.org/obo/GO_0055022 negative regulation of cardiac muscle tissue growth http://purl.obolibrary.org/obo/GO_0061117 negative regulation of heart growth Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle growth. http://purl.obolibrary.org/obo/GO_0055023 positive regulation of cardiac muscle tissue growth http://purl.obolibrary.org/obo/GO_0060421 positive regulation of heart growth Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle growth. http://purl.obolibrary.org/obo/GO_0055024 regulation of cardiac muscle tissue development http://purl.obolibrary.org/obo/GO_0016202 regulation of striated muscle tissue development Any process that modulates the frequency, rate or extent of cardiac muscle tissue development. http://purl.obolibrary.org/obo/GO_0055025 positive regulation of cardiac muscle tissue development http://purl.obolibrary.org/obo/GO_0055024 regulation of cardiac muscle tissue development Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle tissue development. http://purl.obolibrary.org/obo/GO_0055026 negative regulation of cardiac muscle tissue development http://purl.obolibrary.org/obo/GO_0055024 regulation of cardiac muscle tissue development Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle tissue development. http://purl.obolibrary.org/obo/GO_0055056 D-glucose transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0015149 hexose transmembrane transporter activity Enables the transfer of the D-enantiomer of the hexose monosaccharide glucose from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0055089 fatty acid homeostasis http://purl.obolibrary.org/obo/GO_0055088 lipid homeostasis Any process involved in the maintenance of an internal steady state of fatty acid within an organism or cell. http://purl.obolibrary.org/obo/GO_0055094 response to lipoprotein particle http://purl.obolibrary.org/obo/GO_0009719 response to endogenous stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoprotein particle stimulus. http://purl.obolibrary.org/obo/GO_0055107 Golgi to secretory granule transport http://purl.obolibrary.org/obo/GO_0046907 intracellular transport The directed movement of proteins from the Golgi to a secretory granule. The secretory granule is a membrane-bounded particle, usually protein, formed in the granular endoplasmic reticulum and the Golgi complex. http://purl.obolibrary.org/obo/GO_0055111 ingression involved in gastrulation with mouth forming second http://purl.obolibrary.org/obo/GO_0042074 cell migration involved in gastrulation The migration of individual cells into the embryo involved in deuterostomic gastrulation. http://purl.obolibrary.org/obo/GO_0055118 negative regulation of cardiac muscle contraction http://purl.obolibrary.org/obo/GO_0055117 regulation of cardiac muscle contraction Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle contraction. http://purl.obolibrary.org/obo/GO_0055127 vibrational conductance of sound to the inner ear http://purl.obolibrary.org/obo/GO_0032501 multicellular organismal process The transmission of vibrations via ossicles to the inner ear. http://purl.obolibrary.org/obo/GO_0060005 vestibular reflex http://purl.obolibrary.org/obo/GO_0060004 reflex A reflex process in which a response to an angular or linear acceleration stimulus begins with an afferent nerve impulse from a receptor in the inner ear and ends with the compensatory action of eye muscles. Signaling never reaches a level of consciousness. http://purl.obolibrary.org/obo/GO_0060007 linear vestibuloocular reflex http://purl.obolibrary.org/obo/GO_0060005 vestibular reflex A vestibular reflex by which a response to a linear acceleration stimulus begins with an afferent nerve impulse from a receptor in the otolith and ends with the compensatory action of eye muscles. Signaling never reaches a level of consciousness. http://purl.obolibrary.org/obo/GO_0060008 Sertoli cell differentiation http://purl.obolibrary.org/obo/GO_0030855 epithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a Sertoli cell. A Sertoli cell is a supporting cell projecting inward from the basement membrane of seminiferous tubules. http://purl.obolibrary.org/obo/GO_0060009 Sertoli cell development http://purl.obolibrary.org/obo/GO_0003006 developmental process involved in reproduction The process whose specific outcome is the progression of a Sertoli cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a Sertoli cell fate. http://purl.obolibrary.org/obo/GO_0060011 Sertoli cell proliferation http://purl.obolibrary.org/obo/GO_0050673 epithelial cell proliferation The multiplication or reproduction of Sertoli cells, resulting in the expansion of the Sertoli cell population. A Sertoli cell is a supporting cell projecting inward from the basement membrane of seminiferous tubules. http://purl.obolibrary.org/obo/GO_0060012 synaptic transmission, glycinergic http://purl.obolibrary.org/obo/GO_0007268 chemical synaptic transmission The vesicular release of glycine from a presynapse, across a chemical synapse, the subsequent activation of glycine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse. http://purl.obolibrary.org/obo/GO_0060014 granulosa cell differentiation http://purl.obolibrary.org/obo/GO_0030855 epithelial cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a granulosa cell, a supporting cell for the developing female gamete in the ovary of mammals. http://purl.obolibrary.org/obo/GO_0060016 granulosa cell development http://purl.obolibrary.org/obo/GO_0002064 epithelial cell development The process whose specific outcome is the progression of a granulosa cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a granulosa cell fate. http://purl.obolibrary.org/obo/GO_0060017 parathyroid gland development http://purl.obolibrary.org/obo/GO_0048732 gland development The process whose specific outcome is the progression of the parathyroid gland over time, from its formation to the mature structure. The parathyroid gland is an organ specialised for secretion of parathyroid hormone. http://purl.obolibrary.org/obo/GO_0060020 Bergmann glial cell differentiation http://purl.obolibrary.org/obo/GO_0048708 astrocyte differentiation The process in which neuroepithelial cells of the neural tube give rise to Brgmann glial cells, specialized bipotential progenitors cells of the cerebellum. Differentiation includes the processes involved in commitment of a cell to a specific fate. http://purl.obolibrary.org/obo/GO_0060021 roof of mouth development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The biological process whose specific outcome is the progression of the roof of the mouth from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The roof of the mouth is the partition that separates the nasal and oral cavities. http://purl.obolibrary.org/obo/GO_0060034 notochord cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features cells that make up the notochord. Differentiation includes the processes involved in commitment of a cell to a notochord cell fate. http://purl.obolibrary.org/obo/GO_0060037 pharyngeal system development http://purl.obolibrary.org/obo/GO_0048731 system development The process whose specific outcome is the progression of the pharyngeal system over time, from its formation to the mature structure. The pharyngeal system is a transient embryonic complex that is specific to vertebrates. It comprises the pharyngeal arches, bulges of tissues of mesoderm and neural crest derivation through which pass nerves and pharyngeal arch arteries. The arches are separated internally by pharyngeal pouches, evaginations of foregut endoderm, and externally by pharyngeal clefts, invaginations of surface ectoderm. The development of the system ends when the structure it contributes to are forming: the thymus, thyroid, parathyroids, maxilla, mandible, aortic arch, cardiac outflow tract, external and middle ear. http://purl.obolibrary.org/obo/GO_0060038 cardiac muscle cell proliferation http://purl.obolibrary.org/obo/GO_0014855 striated muscle cell proliferation The expansion of a cardiac muscle cell population by cell division. http://purl.obolibrary.org/obo/GO_0060040 retinal bipolar neuron differentiation http://purl.obolibrary.org/obo/GO_1905962 glutamatergic neuron differentiation The process in which a relatively unspecialized cell acquires specialized features of a bipolar cell, the last neuron to be generated in the retina. http://purl.obolibrary.org/obo/GO_0060043 regulation of cardiac muscle cell proliferation http://purl.obolibrary.org/obo/GO_0055021 regulation of cardiac muscle tissue growth Any process that modulates the frequency, rate or extent of cardiac muscle cell proliferation. http://purl.obolibrary.org/obo/GO_0060044 negative regulation of cardiac muscle cell proliferation http://purl.obolibrary.org/obo/GO_0060043 regulation of cardiac muscle cell proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle cell proliferation. http://purl.obolibrary.org/obo/GO_0060045 positive regulation of cardiac muscle cell proliferation http://purl.obolibrary.org/obo/GO_0060043 regulation of cardiac muscle cell proliferation Any process that activates or increases the frequency, rate or extent of cardiac muscle cell proliferation. http://purl.obolibrary.org/obo/GO_0060054 positive regulation of epithelial cell proliferation involved in wound healing http://purl.obolibrary.org/obo/GO_0050679 positive regulation of epithelial cell proliferation Any process that activates or increases the rate or extent of epithelial cell proliferation, contributing to the restoration of integrity to a damaged tissue following an injury. http://purl.obolibrary.org/obo/GO_0060055 angiogenesis involved in wound healing http://purl.obolibrary.org/obo/GO_0001525 angiogenesis Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to a damaged tissue, following an injury. http://purl.obolibrary.org/obo/GO_0060067 cervix development http://purl.obolibrary.org/obo/GO_0048608 reproductive structure development The reproductive developmental process whose specific outcome is the progression of the cervix over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0060068 vagina development http://purl.obolibrary.org/obo/GO_0030540 female genitalia development The reproductive developmental process whose specific outcome is the progression of the vagina over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0060073 micturition http://purl.obolibrary.org/obo/GO_0003014 renal system process The regulation of body fluids process in which parasympathetic nerves stimulate the bladder wall muscle to contract and expel urine from the body. http://purl.obolibrary.org/obo/GO_0060076 excitatory synapse http://purl.obolibrary.org/obo/GO_0045202 synapse A synapse in which an action potential in the presynaptic cell increases the probability of an action potential occurring in the postsynaptic cell. http://purl.obolibrary.org/obo/GO_0060078 regulation of postsynaptic membrane potential http://purl.obolibrary.org/obo/GO_0042391 regulation of membrane potential Any process that modulates the potential difference across a post-synaptic membrane. http://purl.obolibrary.org/obo/GO_0060082 eye blink reflex http://purl.obolibrary.org/obo/GO_0060004 reflex The reflex process in which a mechanical stimulus applied to the eye elicits a response of the eyelid closing. http://purl.obolibrary.org/obo/GO_0060083 smooth muscle contraction involved in micturition http://purl.obolibrary.org/obo/GO_0014832 urinary bladder smooth muscle contraction The process leading to shortening and/or development of tension in the urinary bladder smooth muscle tissue involved in the expulsion urine from the body. http://purl.obolibrary.org/obo/GO_0060084 synaptic transmission involved in micturition http://purl.obolibrary.org/obo/GO_0007274 neuromuscular synaptic transmission The process of communication from a neuron to a smooth muscle in the bladder that contributes to the expulsion of urine from the body. http://purl.obolibrary.org/obo/GO_0060092 regulation of synaptic transmission, glycinergic http://purl.obolibrary.org/obo/GO_0050804 modulation of chemical synaptic transmission Any process that modulates the frequency, rate or extent of glycinergic synaptic transmission. Glycinergic synaptic transmission is the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glycine. http://purl.obolibrary.org/obo/GO_0060093 negative regulation of synaptic transmission, glycinergic http://purl.obolibrary.org/obo/GO_0060092 regulation of synaptic transmission, glycinergic Any process that stops or decreases the frequency, rate or extent of glycinergic synaptic transmission. Glycinergic synaptic transmission is the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glycine. http://purl.obolibrary.org/obo/GO_0060094 positive regulation of synaptic transmission, glycinergic http://purl.obolibrary.org/obo/GO_0060092 regulation of synaptic transmission, glycinergic Any process that activates or increases the frequency, rate or extent of glycinergic synaptic transmission. Glycinergic synaptic transmission is the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glycine. http://purl.obolibrary.org/obo/GO_0060096 serotonin secretion, neurotransmission http://purl.obolibrary.org/obo/GO_0007269 neurotransmitter secretion The regulated release of serotonin by a cell, in which released serotonin acts as a neurotransmitter. http://purl.obolibrary.org/obo/GO_0060114 vestibular receptor cell differentiation http://purl.obolibrary.org/obo/GO_0060113 inner ear receptor cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a vestibular hair cell. http://purl.obolibrary.org/obo/GO_0060116 vestibular receptor cell morphogenesis http://purl.obolibrary.org/obo/GO_0048667 cell morphogenesis involved in neuron differentiation Any process that alters the size or shape of a vestibular receptor cell. http://purl.obolibrary.org/obo/GO_0060118 vestibular receptor cell development http://purl.obolibrary.org/obo/GO_0060119 inner ear receptor cell development The process whose specific outcome is the progression of a vestibular receptor cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. http://purl.obolibrary.org/obo/GO_0060119 inner ear receptor cell development http://purl.obolibrary.org/obo/GO_0048666 neuron development The process whose specific outcome is the progression of an inner ear receptor cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. http://purl.obolibrary.org/obo/GO_0060123 regulation of growth hormone secretion http://purl.obolibrary.org/obo/GO_0090276 regulation of peptide hormone secretion Any process that modulates the frequency, rate or extent of the regulated release of growth hormone from a cell. http://purl.obolibrary.org/obo/GO_0060124 positive regulation of growth hormone secretion http://purl.obolibrary.org/obo/GO_0060123 regulation of growth hormone secretion Any process that increases the frequency, rate or extent of the regulated release of growth hormone from a cell. http://purl.obolibrary.org/obo/GO_0060125 negative regulation of growth hormone secretion http://purl.obolibrary.org/obo/GO_0060123 regulation of growth hormone secretion Any process that decreases or stops the frequency, rate or extent of the regulated release of growth hormone from a cell. http://purl.obolibrary.org/obo/GO_0060126 somatotropin secreting cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a somatotropin secreting cell. A somatotropin secreting cell is an acidophilic cell of the anterior pituitary that produces growth hormone, somatotropin. http://purl.obolibrary.org/obo/GO_0060127 prolactin secreting cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a prolactin secreting cell. A prolactin secreting cell is an acidophilic cell of the anterior pituitary that produces prolactin. http://purl.obolibrary.org/obo/GO_0060128 corticotropin hormone secreting cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a corticotropic hormone secreting cell. An corticotropic hormone secreting cell is a basophil cell of the anterior pituitary that produces corticotropin. http://purl.obolibrary.org/obo/GO_0060129 thyroid-stimulating hormone-secreting cell differentiation http://purl.obolibrary.org/obo/GO_0061101 neuroendocrine cell differentiation The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a thyroid-stimulating hormone-secreting cell. A thyroid-stimulating hormone-secreting cell is a basophil cell of the anterior pituitary that produces thyroid-stimulating hormone, thyrotrophin. http://purl.obolibrary.org/obo/GO_0060130 thyroid-stimulating hormone-secreting cell development http://purl.obolibrary.org/obo/GO_0021884 forebrain neuron development The process whose specific outcome is the progression of a thyroid-stimulating hormone-secreting cell over time, from its formation to the mature structure. A thyroid-stimulating hormone-secreting cell is a basophil cell of the anterior pituitary that produces thyroid stimulating hormone, thyrotrophin. http://purl.obolibrary.org/obo/GO_0060131 corticotropin hormone secreting cell development http://purl.obolibrary.org/obo/GO_0048468 cell development The process whose specific outcome is the progression of a corticotropic hormone secreting cell over time, from its formation to the mature structure. An corticotropic hormone secreting cell is a basophil cell of the anterior pituitary that produces corticotropin. http://purl.obolibrary.org/obo/GO_0060132 prolactin secreting cell development http://purl.obolibrary.org/obo/GO_0048468 cell development The process whose specific outcome is the progression of a prolactin secreting cell over time, from its formation to the mature structure. A prolactin secreting cell is an acidophilic cell of the anterior pituitary that produces prolactin. http://purl.obolibrary.org/obo/GO_0060133 somatotropin secreting cell development http://purl.obolibrary.org/obo/GO_0048468 cell development The process whose specific outcome is the progression of a somatotropin secreting cell over time, from its formation to the mature structure. A somatotropin secreting cell is an acidophilic cell of the anterior pituitary that produces growth hormone, somatotropin. http://purl.obolibrary.org/obo/GO_0060136 embryonic process involved in female pregnancy http://purl.obolibrary.org/obo/GO_0048609 multicellular organismal reproductive process A reproductive process occurring in the embryo or fetus that allows the embryo or fetus to develop within the mother. http://purl.obolibrary.org/obo/GO_0060157 urinary bladder development http://purl.obolibrary.org/obo/GO_0048513 animal organ development The process whose specific outcome is the progression of the urinary bladder over time, from its formation to the mature structure. The urinary bladder is an elastic, muscular sac situated in the anterior part of the pelvic cavity in which urine collects before excretion. http://purl.obolibrary.org/obo/GO_0060166 olfactory pit development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The biological process whose specific outcome is the progression of the olfactory pit from an initial condition to its mature state. This process begins with the formation of the olfactory pit, which is an indentation of the olfactory placode, and ends when the pits hollows out to form the nasopharynx. http://purl.obolibrary.org/obo/GO_0060214 endocardium formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis Formation of the endocardium of the heart. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers. http://purl.obolibrary.org/obo/GO_0060215 primitive hemopoiesis http://purl.obolibrary.org/obo/GO_0035162 embryonic hemopoiesis A first transient wave of blood cell production that, in vertebrates, gives rise to erythrocytes (red blood cells) and myeloid cells. http://purl.obolibrary.org/obo/GO_0060217 hemangioblast cell differentiation http://purl.obolibrary.org/obo/GO_0048333 mesodermal cell differentiation The process in which a relatively unspecialized cell acquires the characteristics of a mature hemangioblast. Hemangioblasts are the proposed common precursor of blood and endothelial lineages. http://purl.obolibrary.org/obo/GO_0060218 hematopoietic stem cell differentiation http://purl.obolibrary.org/obo/GO_0048863 stem cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a hematopoietic stem cell. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells. http://purl.obolibrary.org/obo/GO_0060221 retinal rod cell differentiation http://purl.obolibrary.org/obo/GO_0060219 camera-type eye photoreceptor cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a retinal rod cell. http://purl.obolibrary.org/obo/GO_0060263 regulation of respiratory burst http://purl.obolibrary.org/obo/GO_0019222 regulation of metabolic process Any process that modulates the rate frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals. http://purl.obolibrary.org/obo/GO_0060264 regulation of respiratory burst involved in inflammatory response http://purl.obolibrary.org/obo/GO_0060263 regulation of respiratory burst Any process that modulates the rate, frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases made as a defense response ; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals. http://purl.obolibrary.org/obo/GO_0060265 positive regulation of respiratory burst involved in inflammatory response http://purl.obolibrary.org/obo/GO_0060267 positive regulation of respiratory burst Any process that increases the rate, frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases made as a defense response ; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals. http://purl.obolibrary.org/obo/GO_0060266 negative regulation of respiratory burst involved in inflammatory response http://purl.obolibrary.org/obo/GO_0060268 negative regulation of respiratory burst Any process that decreases the rate, frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases made as a defense response ; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals. http://purl.obolibrary.org/obo/GO_0060267 positive regulation of respiratory burst http://purl.obolibrary.org/obo/GO_0060263 regulation of respiratory burst Any process that increases the rate frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals. http://purl.obolibrary.org/obo/GO_0060268 negative regulation of respiratory burst http://purl.obolibrary.org/obo/GO_0060263 regulation of respiratory burst Any process that decreases the rate frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals. http://purl.obolibrary.org/obo/GO_0060269 centripetally migrating follicle cell migration http://purl.obolibrary.org/obo/GO_0007297 follicle cell of egg chamber migration The cell migration process in which a follicle cell migrates as part of an epithelial sheet between the nurse cells and the oocyte. At the end of migration, they cover the anterior of the oocyte. http://purl.obolibrary.org/obo/GO_0060285 cilium-dependent cell motility http://purl.obolibrary.org/obo/GO_0001539 cilium or flagellum-dependent cell motility Cell motility due to the motion of one or more eukaryotic cilia. A eukaryotic cilium is a specialized organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole. http://purl.obolibrary.org/obo/GO_0060294 cilium movement involved in cell motility http://purl.obolibrary.org/obo/GO_0003341 cilium movement Movement of cilia mediated by motor proteins that contributes to the movement of a cell. http://purl.obolibrary.org/obo/GO_0060295 regulation of cilium movement involved in cell motility http://purl.obolibrary.org/obo/GO_1902019 regulation of cilium-dependent cell motility Any process that modulates the rate frequency or extent of cilium movement involved in ciliary motility. http://purl.obolibrary.org/obo/GO_0060297 regulation of sarcomere organization http://purl.obolibrary.org/obo/GO_0110020 regulation of actomyosin structure organization Any process that modulates the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs. http://purl.obolibrary.org/obo/GO_0060298 positive regulation of sarcomere organization http://purl.obolibrary.org/obo/GO_0060297 regulation of sarcomere organization Any process that increases the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs. http://purl.obolibrary.org/obo/GO_0060299 negative regulation of sarcomere organization http://purl.obolibrary.org/obo/GO_0060297 regulation of sarcomere organization Any process that decreases the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs. http://purl.obolibrary.org/obo/GO_0060306 regulation of membrane repolarization http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process Any process that modulates the establishment or extent of a membrane potential in the polarizing direction towards the resting potential, usually from positive to negative. http://purl.obolibrary.org/obo/GO_0060307 regulation of ventricular cardiac muscle cell membrane repolarization http://purl.obolibrary.org/obo/GO_0099623 regulation of cardiac muscle cell membrane repolarization Any process that modulates the establishment or extent of a membrane potential in the polarizing direction towards the resting potential in a ventricular cardiomyocyte. http://purl.obolibrary.org/obo/GO_0060312 regulation of blood vessel remodeling http://purl.obolibrary.org/obo/GO_0034103 regulation of tissue remodeling Any process that modulates the rate, frequency or extent of blood vessel remodeling, the reorganization or renovation of existing blood vessels. http://purl.obolibrary.org/obo/GO_0060313 negative regulation of blood vessel remodeling http://purl.obolibrary.org/obo/GO_0060312 regulation of blood vessel remodeling Any process that decreases the rate, frequency or extent of blood vessel remodeling, the reorganization or renovation of existing blood vessels. http://purl.obolibrary.org/obo/GO_0060323 head morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structures of the head are generated and organized. The head is the anterior-most division of the body. http://purl.obolibrary.org/obo/GO_0060324 face development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The biological process whose specific outcome is the progression of a face from an initial condition to its mature state. The face is the ventral division of the head. http://purl.obolibrary.org/obo/GO_0060325 face morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structures of the face are generated and organized. The face is the ventral division of the head. http://purl.obolibrary.org/obo/GO_0060343 trabecula formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process of creating a trabecula in an organ. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue. http://purl.obolibrary.org/obo/GO_0060344 liver trabecula formation http://purl.obolibrary.org/obo/GO_0060343 trabecula formation The process of creating a trabecula in the liver. A trabecula is a tissue element in the form of a small beam, strut or rod. http://purl.obolibrary.org/obo/GO_0060345 spleen trabecula formation http://purl.obolibrary.org/obo/GO_0060343 trabecula formation The process of creating a trabecula in the spleen. A trabecula is a tissue element in the form of a small beam, strut or rod. http://purl.obolibrary.org/obo/GO_0060347 heart trabecula formation http://purl.obolibrary.org/obo/GO_0060343 trabecula formation The process of creating a trabecula in the heart. A trabecula is a tissue element in the form of a small beam, strut or rod. http://purl.obolibrary.org/obo/GO_0060349 bone morphogenesis http://purl.obolibrary.org/obo/GO_0009887 animal organ morphogenesis The process in which bones are generated and organized. http://purl.obolibrary.org/obo/GO_0060363 cranial suture morphogenesis http://purl.obolibrary.org/obo/GO_0097094 craniofacial suture morphogenesis The process in which any suture between cranial bones is generated and organized. http://purl.obolibrary.org/obo/GO_0060364 frontal suture morphogenesis http://purl.obolibrary.org/obo/GO_0060363 cranial suture morphogenesis The process in which the frontal suture is generated and organized. http://purl.obolibrary.org/obo/GO_0060372 regulation of atrial cardiac muscle cell membrane repolarization http://purl.obolibrary.org/obo/GO_0099623 regulation of cardiac muscle cell membrane repolarization Any process that modulates the establishment or extent of a membrane potential in the polarizing direction towards the resting potential in an atrial cardiomyocyte. http://purl.obolibrary.org/obo/GO_0060374 mast cell differentiation http://purl.obolibrary.org/obo/GO_0002573 myeloid leukocyte differentiation The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a mast cell. A mast cell is a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation. http://purl.obolibrary.org/obo/GO_0060375 regulation of mast cell differentiation http://purl.obolibrary.org/obo/GO_0002761 regulation of myeloid leukocyte differentiation Any process that modulates the rate, frequency or extent of mast cell differentiation, the process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a mast cell. A mast cell is a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation. http://purl.obolibrary.org/obo/GO_0060376 positive regulation of mast cell differentiation http://purl.obolibrary.org/obo/GO_0060375 regulation of mast cell differentiation Any process that increases the rate, frequency or extent of mast cell differentiation, the process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a mast cell. A mast cell is a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation. http://purl.obolibrary.org/obo/GO_0060377 negative regulation of mast cell differentiation http://purl.obolibrary.org/obo/GO_0060375 regulation of mast cell differentiation Any process that decreases the rate, frequency or extent of mast cell differentiation, the process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a mast cell. A mast cell is a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation. http://purl.obolibrary.org/obo/GO_0060408 regulation of acetylcholine metabolic process http://purl.obolibrary.org/obo/GO_0080090 regulation of primary metabolic process Any process that modulates the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues. http://purl.obolibrary.org/obo/GO_0060409 positive regulation of acetylcholine metabolic process http://purl.obolibrary.org/obo/GO_0060408 regulation of acetylcholine metabolic process Any process that increases the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues. http://purl.obolibrary.org/obo/GO_0060414 aorta smooth muscle tissue morphogenesis http://purl.obolibrary.org/obo/GO_0060415 muscle tissue morphogenesis The process in which the structure of the smooth muscle tissue surrounding the aorta is generated and organized. An aorta is an artery that carries blood from the heart to other parts of the body. http://purl.obolibrary.org/obo/GO_0060420 regulation of heart growth http://purl.obolibrary.org/obo/GO_2000026 regulation of multicellular organismal development Any process that modulates the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart. http://purl.obolibrary.org/obo/GO_0060421 positive regulation of heart growth http://purl.obolibrary.org/obo/GO_0060420 regulation of heart growth Any process that increases the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart. http://purl.obolibrary.org/obo/GO_0060425 lung morphogenesis http://purl.obolibrary.org/obo/GO_0009887 animal organ morphogenesis The process in which the anatomical structures of the lung are generated and organized. http://purl.obolibrary.org/obo/GO_0060426 lung vasculature development http://purl.obolibrary.org/obo/GO_0001944 vasculature development The biological process whose specific outcome is the progression of a lung vasculature from an initial condition to its mature state. This process begins with the formation of the lung vasculature and ends with the mature structure. The lung vasculature is composed of the tubule structures that carry blood or lymph in the lungs. http://purl.obolibrary.org/obo/GO_0060427 lung connective tissue development http://purl.obolibrary.org/obo/GO_0061448 connective tissue development The biological process whose specific outcome is the progression of lung connective tissue from an initial condition to its mature state. This process begins with the formation of lung connective tissue and ends with the mature structure. The lung connective tissue is a material made up of fibers forming a framework and support structure for the lungs. http://purl.obolibrary.org/obo/GO_0060428 lung epithelium development http://purl.obolibrary.org/obo/GO_0060429 epithelium development The biological process whose specific outcome is the progression of the lung epithelium from an initial condition to its mature state. This process begins with the formation of lung epithelium and ends with the mature structure. The lung epithelium is the specialized epithelium that lines the inside of the lung. http://purl.obolibrary.org/obo/GO_0060431 primary lung bud formation http://purl.obolibrary.org/obo/GO_0060572 morphogenesis of an epithelial bud The morphogenetic process in which the foregut region specified to become the lung forms the initial left and right buds. http://purl.obolibrary.org/obo/GO_0060433 bronchus development http://purl.obolibrary.org/obo/GO_0030323 respiratory tube development The biological process whose specific outcome is the progression of a bronchus from an initial condition to its mature state. This process begins with the formation of the bronchus and ends with the mature structure. The bronchus is the portion of the airway that connects to the lungs. http://purl.obolibrary.org/obo/GO_0060434 bronchus morphogenesis http://purl.obolibrary.org/obo/GO_0009887 animal organ morphogenesis The process in which the bronchus is generated and organized. The bronchus is the portion of the airway that connects to the lungs. http://purl.obolibrary.org/obo/GO_0060435 bronchiole development http://purl.obolibrary.org/obo/GO_0030323 respiratory tube development The biological process whose specific outcome is the progression of a bronchiole from an initial condition to its mature state. This process begins with the formation of the bronchiole and ends with the mature structure. A bronchiole is the first airway branch that no longer contains cartilage; it is a branch of the bronchi. http://purl.obolibrary.org/obo/GO_0060436 bronchiole morphogenesis http://purl.obolibrary.org/obo/GO_0035239 tube morphogenesis The process in which a bronchiole is generated and organized. A bronchiole is the first airway branch that no longer contains cartilage; it is a branch of the bronchi. http://purl.obolibrary.org/obo/GO_0060437 lung growth http://purl.obolibrary.org/obo/GO_0035265 organ growth The increase in size or mass of a lung. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the esophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into tubes ending in small air cells, in the walls of which the blood circulates in a fine network of capillaries. In mammals the lungs are more or less divided into lobes, and each lung occupies a separate cavity in the thorax. http://purl.obolibrary.org/obo/GO_0060438 trachea development http://purl.obolibrary.org/obo/GO_0048513 animal organ development The process whose specific outcome is the progression of a trachea over time, from its formation to the mature structure. The trachea is the portion of the airway that attaches to the bronchi as it branches. http://purl.obolibrary.org/obo/GO_0060439 trachea morphogenesis http://purl.obolibrary.org/obo/GO_0009887 animal organ morphogenesis The process in which a trachea is generated and organized. The trachea is the portion of the airway that attaches to the bronchi as it branches. http://purl.obolibrary.org/obo/GO_0060440 trachea formation http://purl.obolibrary.org/obo/GO_0048645 animal organ formation The process pertaining to the initial formation of a trachea from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the trachea is recognizable. The trachea is the portion of the airway that attaches to the bronchi as it branches. http://purl.obolibrary.org/obo/GO_0060441 epithelial tube branching involved in lung morphogenesis http://purl.obolibrary.org/obo/GO_0048754 branching morphogenesis of an epithelial tube The process in which a highly ordered sequence of patterning events generates the branched epithelial tubes of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units. http://purl.obolibrary.org/obo/GO_0060442 branching involved in prostate gland morphogenesis http://purl.obolibrary.org/obo/GO_0060740 prostate gland epithelium morphogenesis The process in which the branching structure of the prostate gland is generated and organized. A branch is a division or offshoot from a main stem. http://purl.obolibrary.org/obo/GO_0060443 mammary gland morphogenesis http://purl.obolibrary.org/obo/GO_0022612 gland morphogenesis The process in which anatomical structures of the mammary gland are generated and organized. Morphogenesis refers to the creation of shape. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk. http://purl.obolibrary.org/obo/GO_0060444 branching involved in mammary gland duct morphogenesis http://purl.obolibrary.org/obo/GO_0048754 branching morphogenesis of an epithelial tube The process in which the branching structure of the mammary gland duct is generated and organized. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk. http://purl.obolibrary.org/obo/GO_0060445 branching involved in salivary gland morphogenesis http://purl.obolibrary.org/obo/GO_0061138 morphogenesis of a branching epithelium The process in which the branching structure of the salivary gland is generated and organized. http://purl.obolibrary.org/obo/GO_0060450 positive regulation of hindgut contraction http://purl.obolibrary.org/obo/GO_0043134 regulation of hindgut contraction Any process that increases the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine. http://purl.obolibrary.org/obo/GO_0060451 negative regulation of hindgut contraction http://purl.obolibrary.org/obo/GO_0060457 negative regulation of digestive system process Any process that decreases the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine. http://purl.obolibrary.org/obo/GO_0060452 positive regulation of cardiac muscle contraction http://purl.obolibrary.org/obo/GO_0055117 regulation of cardiac muscle contraction Any process that increases the frequency, rate or extent of cardiac muscle contraction. http://purl.obolibrary.org/obo/GO_0060453 regulation of gastric acid secretion http://purl.obolibrary.org/obo/GO_0044058 regulation of digestive system process Any process that modulates the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion. http://purl.obolibrary.org/obo/GO_0060454 positive regulation of gastric acid secretion http://purl.obolibrary.org/obo/GO_0060453 regulation of gastric acid secretion Any process that increases the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion. http://purl.obolibrary.org/obo/GO_0060455 negative regulation of gastric acid secretion http://purl.obolibrary.org/obo/GO_0060457 negative regulation of digestive system process Any process that decreases the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion. http://purl.obolibrary.org/obo/GO_0060457 negative regulation of digestive system process http://purl.obolibrary.org/obo/GO_0044058 regulation of digestive system process Any process that decreases the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism. http://purl.obolibrary.org/obo/GO_0060458 right lung development http://purl.obolibrary.org/obo/GO_0030324 lung development The biological process whose specific outcome is the progression of a right lung from an initial condition to its mature state. This process begins with the formation of the right lung and ends with the mature structure. The right lung is the lung which is on the right side of the anterior posterior axis looking from a dorsal to ventral aspect. http://purl.obolibrary.org/obo/GO_0060459 left lung development http://purl.obolibrary.org/obo/GO_0030324 lung development The biological process whose specific outcome is the progression of a left lung from an initial condition to its mature state. This process begins with the formation of the left lung and ends with the mature structure. The left lung is the lung which is on the left side of the anterior posterior axis looking from a dorsal to ventral aspect. http://purl.obolibrary.org/obo/GO_0060460 left lung morphogenesis http://purl.obolibrary.org/obo/GO_0060425 lung morphogenesis The process in which anatomical structures of the left lung are generated and organized. http://purl.obolibrary.org/obo/GO_0060461 right lung morphogenesis http://purl.obolibrary.org/obo/GO_0060425 lung morphogenesis The process in which anatomical structures of the right lung are generated and organized. http://purl.obolibrary.org/obo/GO_0060462 lung lobe development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The biological process whose specific outcome is the progression of a lung lobe from an initial condition to its mature state. This process begins with the formation of a lung lobe by branching morphogenesis and ends with the mature structure. A lung lobe is one of the rounded projections that compose the lung. http://purl.obolibrary.org/obo/GO_0060463 lung lobe morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structures of a lung lobe are generated and organized. A lung lobe is a projection that extends from the lung. http://purl.obolibrary.org/obo/GO_0060464 lung lobe formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The developmental process pertaining to the initial formation of a lung lobe from unspecified parts. This process begins with the specific processes that contribute to the appearance of the lobe and ends when the structural rudiment is recognizable. A lung lobe is a projection that extends from the lung. http://purl.obolibrary.org/obo/GO_0060468 prevention of polyspermy http://purl.obolibrary.org/obo/GO_0060467 negative regulation of fertilization The negative regulation of fertilization process that takes place as part of egg activation, ensuring that only a single sperm fertilizes the egg. http://purl.obolibrary.org/obo/GO_0060470 positive regulation of cytosolic calcium ion concentration involved in egg activation http://purl.obolibrary.org/obo/GO_0007204 positive regulation of cytosolic calcium ion concentration The process that increases the concentration of calcium ions in the cytosol after fertilization or the physiological activation of an egg. http://purl.obolibrary.org/obo/GO_0060474 positive regulation of flagellated sperm motility involved in capacitation http://purl.obolibrary.org/obo/GO_1902093 positive regulation of flagellated sperm motility The process in which the controlled movement of a flagellated sperm cell is initiated as part of the process required for flagellated sperm to reach fertilization competence. http://purl.obolibrary.org/obo/GO_0060479 lung cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features of a mature cell found in the lung. Differentiation includes the processes involved in commitment of a cell to a specific fate. http://purl.obolibrary.org/obo/GO_0060480 lung goblet cell differentiation http://purl.obolibrary.org/obo/GO_0061140 lung secretory cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a lung goblet cell. A goblet cell is a cell of the epithelial lining that produces and secretes mucins. http://purl.obolibrary.org/obo/GO_0060481 lobar bronchus epithelium development http://purl.obolibrary.org/obo/GO_0060428 lung epithelium development The biological process whose specific outcome is the progression of a lobar bronchus epithelium from an initial condition to its mature state. This process begins with the formation of the lobar bronchus epithelium and ends with the mature structure. The lobar bronchus epithelium is the tissue made up of epithelial cells that lines the inside of the lobar bronchus. http://purl.obolibrary.org/obo/GO_0060482 lobar bronchus development http://purl.obolibrary.org/obo/GO_0060433 bronchus development The biological process whose specific outcome is the progression of a lobar bronchus from an initial condition to its mature state. This process begins with the formation of the lobar bronchus and ends with the mature structure. The lobar bronchus is the major airway within the respiratory tree that starts by division of the principal bronchi on both sides and ends at the point of its own subdivision into tertiary or segmental bronchi. http://purl.obolibrary.org/obo/GO_0060483 lobar bronchus mesenchyme development http://purl.obolibrary.org/obo/GO_0060484 lung-associated mesenchyme development The biological process whose specific outcome is the progression of a lobar bronchus mesenchyme from an initial condition to its mature state. This process begins with the formation of the lobar bronchus mesenchyme and ends with the mature structure. The lobar bronchus mesenchyme is the mass of tissue composed of mesenchymal cells in the lobar bronchus. http://purl.obolibrary.org/obo/GO_0060484 lung-associated mesenchyme development http://purl.obolibrary.org/obo/GO_0060485 mesenchyme development The biological process whose specific outcome is the progression of a lung-associated mesenchyme from an initial condition to its mature state. This process begins with the formation of lung-associated mesenchyme and ends with the mature structure. Lung-associated mesenchyme is the tissue made up of loosely connected mesenchymal cells in the lung. http://purl.obolibrary.org/obo/GO_0060486 club cell differentiation http://purl.obolibrary.org/obo/GO_0060487 lung epithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a club cell. A club cell is an unciliated epithelial cell found in the respiratory and terminal bronchioles. http://purl.obolibrary.org/obo/GO_0060487 lung epithelial cell differentiation http://purl.obolibrary.org/obo/GO_0060479 lung cell differentiation The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell that contributes to the epithelium of the lung. http://purl.obolibrary.org/obo/GO_0060490 lateral sprouting involved in lung morphogenesis http://purl.obolibrary.org/obo/GO_0060601 lateral sprouting from an epithelium The process in which a branch forms along the side of the lung epithelial tube. http://purl.obolibrary.org/obo/GO_0060496 mesenchymal-epithelial cell signaling involved in lung development http://purl.obolibrary.org/obo/GO_0060638 mesenchymal-epithelial cell signaling Any process that mediates the transfer of information from a mesenchymal cell to an epithelial cell and contributes to the development of the lung. http://purl.obolibrary.org/obo/GO_0060497 mesenchymal-endodermal cell signaling http://purl.obolibrary.org/obo/GO_0007267 cell-cell signaling Any process that mediates the transfer of information between a mesenchymal cell and an endodermal cell. http://purl.obolibrary.org/obo/GO_0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis http://purl.obolibrary.org/obo/GO_2000794 regulation of epithelial cell proliferation involved in lung morphogenesis Any process that increases the rate or frequency of epithelial cell proliferation that results in the lung attaining its shape. http://purl.obolibrary.org/obo/GO_0060502 epithelial cell proliferation involved in lung morphogenesis http://purl.obolibrary.org/obo/GO_0050673 epithelial cell proliferation The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population that contributes to the shaping of the lung. http://purl.obolibrary.org/obo/GO_0060509 type I pneumocyte differentiation http://purl.obolibrary.org/obo/GO_0060487 lung epithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a type I pneumocyte. A type I pneumocyte is a flattened cell with greatly attenuated cytoplasm and a paucity of organelles. http://purl.obolibrary.org/obo/GO_0060510 type II pneumocyte differentiation http://purl.obolibrary.org/obo/GO_0061140 lung secretory cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a type II pneumocyte. A type II pneumocyte is a surfactant secreting cell that contains abundant cytoplasm containing numerous lipid-rich multilamellar bodies. http://purl.obolibrary.org/obo/GO_0060512 prostate gland morphogenesis http://purl.obolibrary.org/obo/GO_0003006 developmental process involved in reproduction The process in which the anatomical structures of a prostate gland are generated and organized. http://purl.obolibrary.org/obo/GO_0060513 prostatic bud formation http://purl.obolibrary.org/obo/GO_0060740 prostate gland epithelium morphogenesis The morphogenetic process in which a region of the fetal urogenital sinus epithelium is specified to become the prostate, resulting in prostate bud outgrowth. http://purl.obolibrary.org/obo/GO_0060525 prostate glandular acinus development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of a glandular acinus of the prostate gland over time, from its initial formation to the mature structure. The glandular acini are the saclike structures of the gland. http://purl.obolibrary.org/obo/GO_0060526 prostate glandular acinus morphogenesis http://purl.obolibrary.org/obo/GO_0060740 prostate gland epithelium morphogenesis The process in which the prostate glandular acini are generated and organized. The glandular acini are the saclike structures of the gland. http://purl.obolibrary.org/obo/GO_0060532 bronchus cartilage development http://purl.obolibrary.org/obo/GO_0051216 cartilage development The process whose specific outcome is the progression of lung cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate. http://purl.obolibrary.org/obo/GO_0060533 bronchus cartilage morphogenesis http://purl.obolibrary.org/obo/GO_0060536 cartilage morphogenesis The process in which the bronchus cartilage is generated and organized. The bronchus cartilage is the connective tissue of the portion of the airway that connects to the lungs. http://purl.obolibrary.org/obo/GO_0060534 trachea cartilage development http://purl.obolibrary.org/obo/GO_0051216 cartilage development The process whose specific outcome is the progression of the tracheal cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate. http://purl.obolibrary.org/obo/GO_0060535 trachea cartilage morphogenesis http://purl.obolibrary.org/obo/GO_0060536 cartilage morphogenesis The process in which the anatomical structures of cartilage in the trachea are generated and organized. http://purl.obolibrary.org/obo/GO_0060539 diaphragm development http://purl.obolibrary.org/obo/GO_0060538 skeletal muscle organ development The progression of the diaphragm over time from its initial formation to the mature structure. The diaphragm is a skeletal muscle that is responsible for contraction and expansion of the lungs. http://purl.obolibrary.org/obo/GO_0060540 diaphragm morphogenesis http://purl.obolibrary.org/obo/GO_0048644 muscle organ morphogenesis The process in which the anatomical structures of the diaphragm are generated and organized. http://purl.obolibrary.org/obo/GO_0060568 regulation of peptide hormone processing http://purl.obolibrary.org/obo/GO_0070613 regulation of protein processing Any process that modulates the rate, frequency or extent of peptide hormone processing. Peptide hormone processing is the generation of a mature peptide hormone by posttranslational processing of a prohormone. http://purl.obolibrary.org/obo/GO_0060569 positive regulation of peptide hormone processing http://purl.obolibrary.org/obo/GO_0060568 regulation of peptide hormone processing Any process that increases the rate, frequency or extent of peptide hormone processing. Peptide hormone processing is the generation of a mature peptide hormone by posttranslational processing of a prohormone. http://purl.obolibrary.org/obo/GO_0060570 negative regulation of peptide hormone processing http://purl.obolibrary.org/obo/GO_0060568 regulation of peptide hormone processing Any process that decreases the rate, frequency or extent of peptide hormone processing. Peptide hormone processing is the generation of a mature peptide hormone by posttranslational processing of a prohormone. http://purl.obolibrary.org/obo/GO_0060572 morphogenesis of an epithelial bud http://purl.obolibrary.org/obo/GO_0060571 morphogenesis of an epithelial fold The morphogenetic process in which a bud forms from an epithelial sheet. A bud is a protrusion that forms form the sheet by localized folding. http://purl.obolibrary.org/obo/GO_0060574 intestinal epithelial cell maturation http://purl.obolibrary.org/obo/GO_0002069 columnar/cuboidal epithelial cell maturation The developmental process, independent of morphogenetic (shape) change, that is required for a columna/cuboidal epithelial cell of the intestine to attain its fully functional state. A columnar/cuboidal epithelial cell of the intestine mature as they migrate from the intestinal crypt to the villus. http://purl.obolibrary.org/obo/GO_0060575 intestinal epithelial cell differentiation http://purl.obolibrary.org/obo/GO_0002065 columnar/cuboidal epithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a columnar/cuboidal epithelial cell of the intestine. http://purl.obolibrary.org/obo/GO_0060576 intestinal epithelial cell development http://purl.obolibrary.org/obo/GO_0002066 columnar/cuboidal epithelial cell development The process whose specific outcome is the progression of a columnar/cuboidal epithelial cell of the intestine over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0060577 pulmonary vein morphogenesis http://purl.obolibrary.org/obo/GO_0048845 venous blood vessel morphogenesis The process in which the anatomical structure of the pulmonary venous blood vessels are generated and organized. Pulmonary veins are blood vessels that transport blood from the lungs to the heart. http://purl.obolibrary.org/obo/GO_0060578 superior vena cava morphogenesis http://purl.obolibrary.org/obo/GO_0048845 venous blood vessel morphogenesis The process in which the anatomical structure of superior vena cava generated and organized. The superior vena cava is a blood vessel that transports blood from the upper body to the heart. http://purl.obolibrary.org/obo/GO_0060586 multicellular organismal-level iron ion homeostasis http://purl.obolibrary.org/obo/GO_0140962 multicellular organismal-level chemical homeostasis A chemical homeostatic process involved in the maintenance of a steady state level of iron within extracellular body fluids, such as blood, xylem or phloem, of a multicellular organism. This is distinct from maintenance of cellular homeostasis, which occurs within a cell. http://purl.obolibrary.org/obo/GO_0060591 chondroblast differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a mesenchymal cell, acquires specialized structural and/or functional features of a chondroblast. Differentiation includes the processes involved in commitment of a cell to a chondroblast fate. A chondroblast is a precursor cell to chondrocytes. http://purl.obolibrary.org/obo/GO_0060592 mammary gland formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process pertaining to the initial formation of the mammary gland from unspecified parts. The process begins with formation of the mammary line and ends when the solid mammary bud invades the primary mammary mesenchyme. http://purl.obolibrary.org/obo/GO_0060596 mammary placode formation http://purl.obolibrary.org/obo/GO_0060788 ectodermal placode formation The developmental process in which the mammary placode forms. The mammary placode is a transient lens shaped structure that will give rise to the mammary bud proper. http://purl.obolibrary.org/obo/GO_0060599 lateral sprouting involved in mammary gland duct morphogenesis http://purl.obolibrary.org/obo/GO_0060601 lateral sprouting from an epithelium The process in which a branch forms along the side of a mammary duct. http://purl.obolibrary.org/obo/GO_0060601 lateral sprouting from an epithelium http://purl.obolibrary.org/obo/GO_0002009 morphogenesis of an epithelium The process in which a branch forms along the side of an epithelium. http://purl.obolibrary.org/obo/GO_0060603 mammary gland duct morphogenesis http://purl.obolibrary.org/obo/GO_0060562 epithelial tube morphogenesis The process in which anatomical structures of the mammary ducts are generated and organized. Mammary ducts are epithelial tubes that transport milk. http://purl.obolibrary.org/obo/GO_0060611 mammary gland fat development http://purl.obolibrary.org/obo/GO_0060612 adipose tissue development The progression of the mammary gland fat over time, from its formation to the mature structure. The mammary fat is an adipose structure in the gland that is invaded by the mammary ducts. http://purl.obolibrary.org/obo/GO_0060615 mammary gland bud formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The morphogenetic process in which a bud forms from the mammary placode. A mammary bud is bulb of epithelial cells that is distinct from the surrounding epidermis. http://purl.obolibrary.org/obo/GO_0060616 mammary gland cord formation http://purl.obolibrary.org/obo/GO_0072175 epithelial tube formation The process in which the mammary gland cord forms by elongation of the mammary bud. The cord is formed once the elongating bud breaks through the mesenchyme and reaches the fat pad. http://purl.obolibrary.org/obo/GO_0060618 nipple development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the nipple over time, from its formation to the mature structure. The nipple is a part of the mammary gland that protrudes from the surface ectoderm. http://purl.obolibrary.org/obo/GO_0060623 regulation of chromosome condensation http://purl.obolibrary.org/obo/GO_0033044 regulation of chromosome organization Any process that modulates the rate, frequency, or extent of chromosome condensation, the progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells. http://purl.obolibrary.org/obo/GO_0060638 mesenchymal-epithelial cell signaling http://purl.obolibrary.org/obo/GO_0007267 cell-cell signaling Any process that mediates the transfer of information from a mesenchymal cell to an epithelial cell where it is received and interpreted. http://purl.obolibrary.org/obo/GO_0060644 mammary gland epithelial cell differentiation http://purl.obolibrary.org/obo/GO_0030855 epithelial cell differentiation The process in which a relatively unspecialized epithelial cell becomes a more specialized epithelial cell of the mammary gland. http://purl.obolibrary.org/obo/GO_0060648 mammary gland bud morphogenesis http://purl.obolibrary.org/obo/GO_0060572 morphogenesis of an epithelial bud The process in which anatomical structures of the mammary gland buds are generated and organized. Mammary gland buds form by an outpocketing of the mammary placodes and grow to invade the mammary fat, when they form the mammary cord. http://purl.obolibrary.org/obo/GO_0060652 mammary gland cord morphogenesis http://purl.obolibrary.org/obo/GO_0060562 epithelial tube morphogenesis The process in which anatomical structures of the mammary gland cord are generated and organized. Mammary gland cords form when the mammary gland bud invades the mammary fat. http://purl.obolibrary.org/obo/GO_0060658 nipple morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the nipple is generated and organized. http://purl.obolibrary.org/obo/GO_0060661 submandibular salivary gland formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The developmental process pertaining to the initial formation of a submandibular salivary gland. This process begins with a thickening of the epithelium next to the tongue and ends when a bud linked to the oral surface is formed. http://purl.obolibrary.org/obo/GO_0060664 epithelial cell proliferation involved in salivary gland morphogenesis http://purl.obolibrary.org/obo/GO_0050673 epithelial cell proliferation The multiplication or reproduction of epithelial cells of the submandibular salivary gland, resulting in the expansion of a cell population and the shaping of the gland. http://purl.obolibrary.org/obo/GO_0060669 embryonic placenta morphogenesis http://purl.obolibrary.org/obo/GO_0048598 embryonic morphogenesis The process in which the embryonic placenta is generated and organized. http://purl.obolibrary.org/obo/GO_0060670 branching involved in labyrinthine layer morphogenesis http://purl.obolibrary.org/obo/GO_0048598 embryonic morphogenesis The process in which the branches of the fetal placental villi are generated and organized. The villous part of the placenta is called the labyrinth layer. http://purl.obolibrary.org/obo/GO_0060671 epithelial cell differentiation involved in embryonic placenta development http://purl.obolibrary.org/obo/GO_0060706 cell differentiation involved in embryonic placenta development The process in which a trophoblast cell acquires specialized features of an epithelial cell of the placental labyrinthine layer. http://purl.obolibrary.org/obo/GO_0060674 placenta blood vessel development http://purl.obolibrary.org/obo/GO_0001568 blood vessel development The process whose specific outcome is the progression of a blood vessel of the placenta over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0060676 ureteric bud formation http://purl.obolibrary.org/obo/GO_0072172 mesonephric tubule formation The developmental process pertaining to the initial formation of the ureteric bud from the Wolffian duct. This process begins when the bud protrudes from the duct and ends when it is a recognizable bud. http://purl.obolibrary.org/obo/GO_0060684 epithelial-mesenchymal cell signaling http://purl.obolibrary.org/obo/GO_0007267 cell-cell signaling Any process that results in the transfer of information from an epithelial cell to a mesenchymal cell where it is interpreted. http://purl.obolibrary.org/obo/GO_0060685 regulation of prostatic bud formation http://purl.obolibrary.org/obo/GO_0060688 regulation of morphogenesis of a branching structure Any process that modulates the rate, frequency, or extent of prostatic bud formation, the morphogenetic process in which a region of the fetal urogenital sinus epithelium is specified to become the prostate, resulting in prostate bud outgrowth. http://purl.obolibrary.org/obo/GO_0060686 negative regulation of prostatic bud formation http://purl.obolibrary.org/obo/GO_0060685 regulation of prostatic bud formation Any process that decreases the rate, frequency, or extent of prostatic bud formation, the morphogenetic process in which a region of the fetal urogenital sinus epithelium is specified to become the prostate, resulting in prostate bud outgrowth. http://purl.obolibrary.org/obo/GO_0060687 regulation of branching involved in prostate gland morphogenesis http://purl.obolibrary.org/obo/GO_0060688 regulation of morphogenesis of a branching structure Any process that modulates the rate, frequency, or extent of prostate gland branching, the process in which the branching structure of the prostate gland is generated and organized. A branch is a division or offshoot from a main stem. http://purl.obolibrary.org/obo/GO_0060688 regulation of morphogenesis of a branching structure http://purl.obolibrary.org/obo/GO_0051239 regulation of multicellular organismal process Any process that modulates the rate, frequency, or extent of branching morphogenesis, the process in which the anatomical structures of branches are generated and organized. http://purl.obolibrary.org/obo/GO_0060689 cell differentiation involved in salivary gland development http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires specialized structural and/or functional features that characterize the cells of the salivary gland. http://purl.obolibrary.org/obo/GO_0060690 epithelial cell differentiation involved in salivary gland development http://purl.obolibrary.org/obo/GO_0060689 cell differentiation involved in salivary gland development The process in which a relatively unspecialized cell acquire specialized structural and/or functional features of an epithelial cell of the salivary gland. http://purl.obolibrary.org/obo/GO_0060691 epithelial cell maturation involved in salivary gland development http://purl.obolibrary.org/obo/GO_0002070 epithelial cell maturation The developmental process, independent of morphogenetic (shape) change, that is required for an epithelial cell of the salivary gland to attain its fully functional state. http://purl.obolibrary.org/obo/GO_0060693 regulation of branching involved in salivary gland morphogenesis http://purl.obolibrary.org/obo/GO_0060688 regulation of morphogenesis of a branching structure Any process that modulates the rate, frequency, or extent of branching morphogenesis in the salivary gland epithelium. http://purl.obolibrary.org/obo/GO_0060706 cell differentiation involved in embryonic placenta development http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires specialized features of the embryonic placenta. http://purl.obolibrary.org/obo/GO_0060707 trophoblast giant cell differentiation http://purl.obolibrary.org/obo/GO_0060706 cell differentiation involved in embryonic placenta development The process in which a relatively unspecialized cell acquires specialized features of a trophoblast giant cell of the placenta. Trophoblast giant cells are the cell of the placenta that line the maternal decidua. http://purl.obolibrary.org/obo/GO_0060708 spongiotrophoblast differentiation http://purl.obolibrary.org/obo/GO_0060706 cell differentiation involved in embryonic placenta development The process in which a relatively unspecialized cell of the ectoplacental cone acquires specialized features of a spongiotrophoblast of the placenta. A spongiotrophoblast cell is a basophilic cell. http://purl.obolibrary.org/obo/GO_0060711 labyrinthine layer development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process in which the labyrinthine layer of the placenta progresses, from its formation to its mature state. http://purl.obolibrary.org/obo/GO_0060712 spongiotrophoblast layer development http://purl.obolibrary.org/obo/GO_0009888 tissue development The process in which the spongiotrophoblast layer of the placenta progresses from its formation to its mature state. http://purl.obolibrary.org/obo/GO_0060713 labyrinthine layer morphogenesis http://purl.obolibrary.org/obo/GO_0048598 embryonic morphogenesis The process in which the labyrinthine layer of the placenta is generated and organized. http://purl.obolibrary.org/obo/GO_0060714 labyrinthine layer formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The developmental process pertaining to the initial formation of the labyrinthine layer of the placenta. http://purl.obolibrary.org/obo/GO_0060716 labyrinthine layer blood vessel development http://purl.obolibrary.org/obo/GO_0060674 placenta blood vessel development The process whose specific outcome is the progression of a blood vessel of the labyrinthine layer of the placenta over time, from its formation to the mature structure. The embryonic vessels grow through the layer to come in close contact with the maternal blood supply. http://purl.obolibrary.org/obo/GO_0060717 chorion development http://purl.obolibrary.org/obo/GO_1903867 extraembryonic membrane development The biological process whose specific outcome is the progression of a chorion from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The chorion is an extraembryonic membrane. http://purl.obolibrary.org/obo/GO_0060718 chorionic trophoblast cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which relatively unspecialized cells of the ectoplacental cone acquire specialized structural and/or functional features that characterize chorionic trophoblasts. These cells will migrate towards the spongiotrophoblast layer and give rise to syncytiotrophoblasts of the labyrinthine layer. http://purl.obolibrary.org/obo/GO_0060719 chorionic trophoblast cell development http://purl.obolibrary.org/obo/GO_0048468 cell development The process whose specific outcome is the progression of the chorionic trophoblast over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. http://purl.obolibrary.org/obo/GO_0060722 cell proliferation involved in embryonic placenta development http://purl.obolibrary.org/obo/GO_0008283 cell population proliferation The multiplication or reproduction of cells, resulting in the expansion of the population in the embryonic placenta. http://purl.obolibrary.org/obo/GO_0060723 regulation of cell proliferation involved in embryonic placenta development http://purl.obolibrary.org/obo/GO_0042127 regulation of cell population proliferation Any process that modulates the rate, frequency, or extent of cell proliferation involved in embryonic placenta development. http://purl.obolibrary.org/obo/GO_0060736 prostate gland growth http://purl.obolibrary.org/obo/GO_0003006 developmental process involved in reproduction The increase in size or mass of the prostate gland where the increase in size or mass has the specific outcome of the progression of the gland, from its formation to its mature state. http://purl.obolibrary.org/obo/GO_0060737 prostate gland morphogenetic growth http://purl.obolibrary.org/obo/GO_0060736 prostate gland growth The differential increase in size or mass of the prostate gland that contributes to the gland attaining its form. http://purl.obolibrary.org/obo/GO_0060738 epithelial-mesenchymal signaling involved in prostate gland development http://purl.obolibrary.org/obo/GO_0060684 epithelial-mesenchymal cell signaling Any process that results in the transfer of information from an epithelial cell to a mesenchymal cell where it is interpreted and contributes to the progression of the prostate gland over time. http://purl.obolibrary.org/obo/GO_0060739 mesenchymal-epithelial cell signaling involved in prostate gland development http://purl.obolibrary.org/obo/GO_0060638 mesenchymal-epithelial cell signaling Any process that mediates the transfer of information from a mesenchymal cell to an epithelial cell where it is received and interpreted contributing to the progression of the prostate gland over time. http://purl.obolibrary.org/obo/GO_0060740 prostate gland epithelium morphogenesis http://purl.obolibrary.org/obo/GO_0003006 developmental process involved in reproduction The process in which the anatomical structures of epithelia of the prostate gland are generated and organized. An epithelium consists of closely packed cells arranged in one or more layers, that covers the outer surfaces of the body or lines any internal cavity or tube. http://purl.obolibrary.org/obo/GO_0060741 prostate gland stromal morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the prostate gland stroma is generated and organized. The prostate gland stroma is made up of the mesenchymal or fibroblast cells of the prostate gland. http://purl.obolibrary.org/obo/GO_0060742 epithelial cell differentiation involved in prostate gland development http://purl.obolibrary.org/obo/GO_0030855 epithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell of the prostate gland. http://purl.obolibrary.org/obo/GO_0060743 epithelial cell maturation involved in prostate gland development http://purl.obolibrary.org/obo/GO_0002070 epithelial cell maturation The developmental process, independent of morphogenetic (shape) change, that is required for an epithelial cell of the prostate gland to attain its fully functional state. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface. http://purl.obolibrary.org/obo/GO_0060749 mammary gland alveolus development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the mammary gland alveolus over time, from its formation to its mature state. The mammary gland alveolus is a sac-like structure that is found in the mature gland. http://purl.obolibrary.org/obo/GO_0060753 regulation of mast cell chemotaxis http://purl.obolibrary.org/obo/GO_0002688 regulation of leukocyte chemotaxis Any process that modulates the rate, frequency or extent of mast cell chemotaxis. Mast cell chemotaxis is the movement of a mast cell in response to an external stimulus. http://purl.obolibrary.org/obo/GO_0060754 positive regulation of mast cell chemotaxis http://purl.obolibrary.org/obo/GO_0060753 regulation of mast cell chemotaxis Any process that increases the rate, frequency or extent of mast cell chemotaxis. Mast cell chemotaxis is the movement of a mast cell in response to an external stimulus. http://purl.obolibrary.org/obo/GO_0060755 negative regulation of mast cell chemotaxis http://purl.obolibrary.org/obo/GO_0060753 regulation of mast cell chemotaxis Any process that decreases the rate, frequency or extent of mast cell chemotaxis. Mast cell chemotaxis is the movement of a mast cell in response to an external stimulus. http://purl.obolibrary.org/obo/GO_0060762 regulation of branching involved in mammary gland duct morphogenesis http://purl.obolibrary.org/obo/GO_0060688 regulation of morphogenesis of a branching structure Any process that modulates the rate, frequency, or extent of branching involved in mammary gland duct morphogenesis. http://purl.obolibrary.org/obo/GO_0060764 cell-cell signaling involved in mammary gland development http://purl.obolibrary.org/obo/GO_0007267 cell-cell signaling Any process that mediates the transfer of information from one cell to another and contributes to the progression of the mammary gland, from its initial state to the mature structure. http://purl.obolibrary.org/obo/GO_0060767 epithelial cell proliferation involved in prostate gland development http://purl.obolibrary.org/obo/GO_0050673 epithelial cell proliferation The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population that contributes to the progression of the prostate gland over time. http://purl.obolibrary.org/obo/GO_0060768 regulation of epithelial cell proliferation involved in prostate gland development http://purl.obolibrary.org/obo/GO_0050678 regulation of epithelial cell proliferation Any process that modulates the rate, frequency or extent of epithelial cell proliferation that contributes to the progression of the prostate gland over time. http://purl.obolibrary.org/obo/GO_0060769 positive regulation of epithelial cell proliferation involved in prostate gland development http://purl.obolibrary.org/obo/GO_0060768 regulation of epithelial cell proliferation involved in prostate gland development Any process that increases the rate, frequency or extent of epithelial cell proliferation that contributes to the progression of the prostate gland over time. http://purl.obolibrary.org/obo/GO_0060770 negative regulation of epithelial cell proliferation involved in prostate gland development http://purl.obolibrary.org/obo/GO_0060768 regulation of epithelial cell proliferation involved in prostate gland development Any process that decreases the rate, frequency or extent of epithelial cell proliferation that contributes to the progression of the prostate gland over time. http://purl.obolibrary.org/obo/GO_0060784 regulation of cell proliferation involved in tissue homeostasis http://purl.obolibrary.org/obo/GO_0042127 regulation of cell population proliferation Any process that modulates the frequency, rate or extent of cell proliferation resulting in the maintenance of a steady-state number of cells within a tissue. http://purl.obolibrary.org/obo/GO_0060785 regulation of apoptosis involved in tissue homeostasis http://purl.obolibrary.org/obo/GO_0042981 regulation of apoptotic process Any process that modulates the occurrence or rate of cell death by apoptosis that results in the maintenance of the steady-state number of cells within a tissue. http://purl.obolibrary.org/obo/GO_0060786 regulation of cell differentiation involved in tissue homeostasis http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the frequency, rate or extent of cell differentiation that contributes to the maintenance of a steady state of a cell type within a tissue. http://purl.obolibrary.org/obo/GO_0060789 hair follicle placode formation http://purl.obolibrary.org/obo/GO_0060788 ectodermal placode formation The developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud. http://purl.obolibrary.org/obo/GO_0060790 tooth placode formation http://purl.obolibrary.org/obo/GO_0060788 ectodermal placode formation The developmental process in which the tooth placode forms. A tooth placode is a thickening of the ectoderm that will give rise to the tooth bud. http://purl.obolibrary.org/obo/GO_0060791 sebaceous gland placode formation http://purl.obolibrary.org/obo/GO_0060788 ectodermal placode formation The developmental process in which a sebaceous gland placode forms. A sebaceous gland placode is a thickening of the ectoderm that will give rise to the sebaceous gland bud. http://purl.obolibrary.org/obo/GO_0060792 sweat gland development http://purl.obolibrary.org/obo/GO_0048732 gland development The progression of the sweat gland over time, from its formation to the mature structure. Sweat glands secrete an aqueous solution that is used in thermoregulation. http://purl.obolibrary.org/obo/GO_0060793 sweat gland placode formation http://purl.obolibrary.org/obo/GO_0060788 ectodermal placode formation The developmental process in which the sweat gland placode forms. An sweat gland placode is a thickening of the ectoderm that will give rise to the sweat gland bud. http://purl.obolibrary.org/obo/GO_0060800 regulation of cell differentiation involved in embryonic placenta development http://purl.obolibrary.org/obo/GO_2000241 regulation of reproductive process Any process that modulates the rate, frequency or extent of cell differentiation that contributes to the progression of the placenta over time, from its initial condition to its mature state. http://purl.obolibrary.org/obo/GO_0060806 negative regulation of cell differentiation involved in embryonic placenta development http://purl.obolibrary.org/obo/GO_0060800 regulation of cell differentiation involved in embryonic placenta development Any process that decreases the rate, frequency or extent of cell differentiation that contributes to the progression of the placenta over time, from its initial condition to its mature state. http://purl.obolibrary.org/obo/GO_0060836 lymphatic endothelial cell differentiation http://purl.obolibrary.org/obo/GO_0045446 endothelial cell differentiation The process in which a venous blood vessel endothelial cell acquires specialized features of a lymphatic vessel endothelial cell, a thin flattened cell that lines the inside surfaces of lymph vessels. http://purl.obolibrary.org/obo/GO_0060837 blood vessel endothelial cell differentiation http://purl.obolibrary.org/obo/GO_0045446 endothelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a blood vessel endothelial cell, a thin flattened cell that lines the inside surfaces of blood vessels. http://purl.obolibrary.org/obo/GO_0060842 arterial endothelial cell differentiation http://purl.obolibrary.org/obo/GO_0060837 blood vessel endothelial cell differentiation The process in which a relatively unspecialized endothelial cell acquires specialized features of an arterial endothelial cell, a thin flattened cell that lines the inside surfaces of arteries. http://purl.obolibrary.org/obo/GO_0060843 venous endothelial cell differentiation http://purl.obolibrary.org/obo/GO_0060837 blood vessel endothelial cell differentiation The process in which a relatively unspecialized endothelial cell acquires specialized features of a venous endothelial cell, a thin flattened cell that lines the inside surfaces of veins. http://purl.obolibrary.org/obo/GO_0060854 branching involved in lymph vessel morphogenesis http://purl.obolibrary.org/obo/GO_0048754 branching morphogenesis of an epithelial tube The process of the coordinated growth and sprouting of lymph vessels giving rise to the organized lymphatic system. http://purl.obolibrary.org/obo/GO_0060876 semicircular canal formation http://purl.obolibrary.org/obo/GO_0035148 tube formation The developmental process pertaining to the initial formation of the semicircular canal from the otic vesicle. This process begins with the regionalization of the vesicle that specifies the area where the vesicles will form and continues through the process of fusion which forms the initial tubes. http://purl.obolibrary.org/obo/GO_0060887 limb epidermis development http://purl.obolibrary.org/obo/GO_0098773 skin epidermis development The process whose specific outcome is the progression of the epidermis of the limb over time, from its formation to the mature structure. The limb epidermis is the outer epithelial layer of the limb, it is a complex stratified squamous epithelium. http://purl.obolibrary.org/obo/GO_0060907 positive regulation of macrophage cytokine production http://purl.obolibrary.org/obo/GO_0010935 regulation of macrophage cytokine production Any process that increases the rate, frequency or extent of macrophage cytokine production. Macrophage cytokine production is the appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. http://purl.obolibrary.org/obo/GO_0060915 mesenchymal cell differentiation involved in lung development http://purl.obolibrary.org/obo/GO_0048762 mesenchymal cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell of the lung. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types. http://purl.obolibrary.org/obo/GO_0060916 mesenchymal cell proliferation involved in lung development http://purl.obolibrary.org/obo/GO_0010463 mesenchymal cell proliferation The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population that contributes to the progression of the lung over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets. http://purl.obolibrary.org/obo/GO_0060920 cardiac pacemaker cell differentiation http://purl.obolibrary.org/obo/GO_0055007 cardiac muscle cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a pacemaker cell. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions. http://purl.obolibrary.org/obo/GO_0060921 sinoatrial node cell differentiation http://purl.obolibrary.org/obo/GO_0060920 cardiac pacemaker cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a sinoatrial (SA) node cell. SA node cells are pacemaker cells that are found in the sinoatrial node. http://purl.obolibrary.org/obo/GO_0060922 atrioventricular node cell differentiation http://purl.obolibrary.org/obo/GO_0060920 cardiac pacemaker cell differentiation The process in which a relatively unspecialized cell acquires specialized features of an atrioventricular (AV) node cell. AV node cells are pacemaker cells that are found in the atrioventricular node. http://purl.obolibrary.org/obo/GO_0060926 cardiac pacemaker cell development http://purl.obolibrary.org/obo/GO_0055013 cardiac muscle cell development The process whose specific outcome is the progression of a pacemaker cell over time, from its formation to the mature state. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions. http://purl.obolibrary.org/obo/GO_0060928 atrioventricular node cell development http://purl.obolibrary.org/obo/GO_0060926 cardiac pacemaker cell development The process whose specific outcome is the progression of an atrioventricular (AV) node cell over time, from its formation to the mature state. http://purl.obolibrary.org/obo/GO_0060931 sinoatrial node cell development http://purl.obolibrary.org/obo/GO_0060926 cardiac pacemaker cell development The process whose specific outcome is the progression of a sinoatrial (SA) node cell over time, from its formation to the mature state. SA node cells are pacemaker cells that are found in the sinoatrial node. http://purl.obolibrary.org/obo/GO_0060933 His-Purkinje system cell development http://purl.obolibrary.org/obo/GO_0055006 cardiac cell development The process whose specific outcome is the progression of a His-Purkinje cell over time, from its formation to the mature state. These cells form the fibers that regulate cardiac muscle contraction in the ventricles. http://purl.obolibrary.org/obo/GO_0060935 cardiac fibroblast cell differentiation http://purl.obolibrary.org/obo/GO_0035051 cardiocyte differentiation The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules. http://purl.obolibrary.org/obo/GO_0060936 cardiac fibroblast cell development http://purl.obolibrary.org/obo/GO_0055006 cardiac cell development The process whose specific outcome is the progression of a cardiac fibroblast over time, from its formation to the mature state. A cardiac fibroblast is a connective tissue cell of the heart which secretes an extracellular matrix rich in collagen and other macromolecules. http://purl.obolibrary.org/obo/GO_0060945 cardiac neuron differentiation http://purl.obolibrary.org/obo/GO_0035051 cardiocyte differentiation The process in which a relatively unspecialized cell acquires specialized features of a neuron of the heart. http://purl.obolibrary.org/obo/GO_0060946 cardiac blood vessel endothelial cell differentiation http://purl.obolibrary.org/obo/GO_0060837 blood vessel endothelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a blood vessel endothelial cell of the heart. Blood vessel endothelial cells are thin flattened cells that line the inside surfaces of blood vessels. http://purl.obolibrary.org/obo/GO_0060950 cardiac glial cell differentiation http://purl.obolibrary.org/obo/GO_0035051 cardiocyte differentiation The process in which a relatively unspecialized cell acquires the specialized features of a glial cell of the heart. http://purl.obolibrary.org/obo/GO_0060952 cardiac glial cell development http://purl.obolibrary.org/obo/GO_0055006 cardiac cell development The process aimed at the progression of a cardiac glial cell over time, from its formation to the fully functional mature cell. http://purl.obolibrary.org/obo/GO_0060956 endocardial cell differentiation http://purl.obolibrary.org/obo/GO_0003348 cardiac endothelial cell differentiation The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an endocardial cell. An endocardial cell is a specialized endothelial cell that makes up the endocardium portion of the heart. The endocardium is the innermost layer of tissue of the heart, and lines the heart chambers. http://purl.obolibrary.org/obo/GO_0060958 endocardial cell development http://purl.obolibrary.org/obo/GO_0055006 cardiac cell development The progression of an endocardial cell over time, from its formation to the mature cell. An endocardial cell is a specialized endothelial cell that makes up the endocardium portion of the heart. http://purl.obolibrary.org/obo/GO_0060959 cardiac neuron development http://purl.obolibrary.org/obo/GO_0055006 cardiac cell development The process whose specific outcome is the progression of a cardiac neuron over time, from its formation to the mature state. http://purl.obolibrary.org/obo/GO_0060978 angiogenesis involved in coronary vascular morphogenesis http://purl.obolibrary.org/obo/GO_0001525 angiogenesis Blood vessel formation in the heart when new vessels emerge from the proliferation of pre-existing blood vessels. http://purl.obolibrary.org/obo/GO_0060979 vasculogenesis involved in coronary vascular morphogenesis http://purl.obolibrary.org/obo/GO_0001570 vasculogenesis The differentiation of endothelial cells from progenitor cells that contributes to blood vessel development in the heart, and the de novo formation of blood vessels and tubes. http://purl.obolibrary.org/obo/GO_0060980 cell migration involved in coronary vasculogenesis http://purl.obolibrary.org/obo/GO_0035441 cell migration involved in vasculogenesis The orderly movement of a cell from one site to another that will contribute to the differentiation of an endothelial cell that will form the blood vessels of the heart. http://purl.obolibrary.org/obo/GO_0060981 cell migration involved in coronary angiogenesis http://purl.obolibrary.org/obo/GO_0060973 cell migration involved in heart development The orderly movement of a cell from one site to another that will contribute to the formation of new blood vessels in the heart from pre-existing blood vessels. http://purl.obolibrary.org/obo/GO_0060982 coronary artery morphogenesis http://purl.obolibrary.org/obo/GO_0048844 artery morphogenesis The process in which the anatomical structures of coronary arteries are generated and organized. Coronary arteries are blood vessels that transport blood to the heart muscle. http://purl.obolibrary.org/obo/GO_0061006 regulation of cell proliferation involved in kidney morphogenesis http://purl.obolibrary.org/obo/GO_0042127 regulation of cell population proliferation Any process that modulates the frequency, rate or extent of cell proliferation that contributes to the shaping of the kidney. http://purl.obolibrary.org/obo/GO_0061007 hepaticobiliary system process http://purl.obolibrary.org/obo/GO_0003008 system process A system process carried out by any of the organs or tissues of the hepaticobiliary system. The hepaticobiliary system is responsible for metabolic and catabolic processing of small molecules absorbed from the blood or gut, hormones and serum proteins, detoxification, storage of glycogen, triglycerides, metals and lipid soluble vitamins and excretion of bile. Included are the synthesis of albumin, blood coagulation factors, complement, and specific binding proteins. http://purl.obolibrary.org/obo/GO_0061010 gallbladder development http://purl.obolibrary.org/obo/GO_0048513 animal organ development The progression of the gallbladder over time, from its initial formation to the mature structure. The gallbladder is a cavitated organ that stores bile. http://purl.obolibrary.org/obo/GO_0061011 hepatic duct development http://purl.obolibrary.org/obo/GO_0061009 common bile duct development The progression of the hepatic duct over time, from its formation to the mature structure. The hepatic duct is the duct that leads from the liver to the common bile duct. http://purl.obolibrary.org/obo/GO_0061017 hepatoblast differentiation http://purl.obolibrary.org/obo/GO_0048863 stem cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a hepatoblast. A hepatoblast is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into hepatocytes and cholangiocytes. http://purl.obolibrary.org/obo/GO_0061029 eyelid development in camera-type eye http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the eyelid in a camera-type eye from its formation to the mature state. The eyelid is a membranous cover that helps protect and lubricate the eye. http://purl.obolibrary.org/obo/GO_0061030 epithelial cell differentiation involved in mammary gland alveolus development http://purl.obolibrary.org/obo/GO_0060644 mammary gland epithelial cell differentiation The process in which a relatively unspecialized epithelial cell becomes a more specialized epithelial cell of the mammary gland alveolus. http://purl.obolibrary.org/obo/GO_0061032 visceral serous pericardium development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the visceral serous pericardium from its formation to the mature structure. The visceral serous pericardium is the inner layer of the pericardium. http://purl.obolibrary.org/obo/GO_0061034 olfactory bulb mitral cell layer development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the olfactory bulb mitral cell layer over time from its initial formation until its mature state. The mitral cell layer is composed of pyramidal neurons whose cell bodies are located between the granule cell layer and the plexiform layer. http://purl.obolibrary.org/obo/GO_0061038 uterus morphogenesis http://purl.obolibrary.org/obo/GO_0009887 animal organ morphogenesis The process in which anatomical structures of the uterus are generated and organized. http://purl.obolibrary.org/obo/GO_0061040 female gonad morphogenesis http://purl.obolibrary.org/obo/GO_0035262 gonad morphogenesis The process in which a female gonad is generated and organized. http://purl.obolibrary.org/obo/GO_0061046 regulation of branching involved in lung morphogenesis http://purl.obolibrary.org/obo/GO_0060688 regulation of morphogenesis of a branching structure Any process that modulates the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units. http://purl.obolibrary.org/obo/GO_0061047 positive regulation of branching involved in lung morphogenesis http://purl.obolibrary.org/obo/GO_0061046 regulation of branching involved in lung morphogenesis Any process that increases the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units. http://purl.obolibrary.org/obo/GO_0061048 negative regulation of branching involved in lung morphogenesis http://purl.obolibrary.org/obo/GO_0061046 regulation of branching involved in lung morphogenesis Any process that decreases the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units. http://purl.obolibrary.org/obo/GO_0061050 regulation of cell growth involved in cardiac muscle cell development http://purl.obolibrary.org/obo/GO_0055021 regulation of cardiac muscle tissue growth Any process that modulates the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state. http://purl.obolibrary.org/obo/GO_0061051 positive regulation of cell growth involved in cardiac muscle cell development http://purl.obolibrary.org/obo/GO_0061050 regulation of cell growth involved in cardiac muscle cell development Any process that increases the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state. http://purl.obolibrary.org/obo/GO_0061052 negative regulation of cell growth involved in cardiac muscle cell development http://purl.obolibrary.org/obo/GO_0061050 regulation of cell growth involved in cardiac muscle cell development Any process that decreases the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state. http://purl.obolibrary.org/obo/GO_0061054 dermatome development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin. http://purl.obolibrary.org/obo/GO_0061055 myotome development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the myotome over time, from its formation to the mature structure. The myotome is the portion of the somite that will give rise to muscle. http://purl.obolibrary.org/obo/GO_0061056 sclerotome development http://purl.obolibrary.org/obo/GO_0060485 mesenchyme development The progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra. http://purl.obolibrary.org/obo/GO_0061068 urethra development http://purl.obolibrary.org/obo/GO_0048513 animal organ development The progression of the urethra over time from its initial formation to the mature structure. The urethra is a renal system organ that carries urine from the bladder to outside the body. http://purl.obolibrary.org/obo/GO_0061069 male urethra development http://purl.obolibrary.org/obo/GO_0061068 urethra development The progression of the male urethra over time from its initial formation to the mature structure. The male urethra is a renal system organ that carries urine from the bladder through the penis to outside the body. http://purl.obolibrary.org/obo/GO_0061070 female urethra development http://purl.obolibrary.org/obo/GO_0061068 urethra development The progression of the female urethra over time from its initial formation to the mature structure. The female urethra is a renal system organ that carries urine from the bladder to outside the body, exiting above the vaginal opening. http://purl.obolibrary.org/obo/GO_0061071 urethra epithelium development http://purl.obolibrary.org/obo/GO_0060429 epithelium development The progression of the urethra epithelium over time from its initial formation to the mature structure. The urethra is a renal system organ that carries urine from the bladder to outside the body. The epithelium is the tubular, planar layer of cells through which the urine passes. http://purl.obolibrary.org/obo/GO_0061072 iris morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the iris is generated and organized. The iris is an anatomical structure in the eye whose opening forms the pupil. The iris is responsible for controlling the diameter and size of the pupil and the amount of light reaching the retina. http://purl.obolibrary.org/obo/GO_0061073 ciliary body morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the ciliary body generated and organized. The ciliary body is the circumferential tissue inside the eye composed of the ciliary muscle and ciliary processes. http://purl.obolibrary.org/obo/GO_0061074 regulation of neural retina development http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells. http://purl.obolibrary.org/obo/GO_0061075 positive regulation of neural retina development http://purl.obolibrary.org/obo/GO_1902868 positive regulation of retina development in camera-type eye Any process that increases the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells. http://purl.obolibrary.org/obo/GO_0061076 negative regulation of neural retina development http://purl.obolibrary.org/obo/GO_1902867 negative regulation of retina development in camera-type eye Any process that decreases the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells. http://purl.obolibrary.org/obo/GO_0061080 right horn of sinus venosus development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the right horn of the sinus venosus from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0061100 lung neuroendocrine cell differentiation http://purl.obolibrary.org/obo/GO_0061140 lung secretory cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a neuroendocrine cell of the lung epithelium. http://purl.obolibrary.org/obo/GO_0061101 neuroendocrine cell differentiation http://purl.obolibrary.org/obo/GO_0060563 neuroepithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a neuroendocrine cell. A neuroendocrine cell is a cell that receives input form a neuron which controls the secretion of an endocrine substance. http://purl.obolibrary.org/obo/GO_0061102 stomach neuroendocrine cell differentiation http://purl.obolibrary.org/obo/GO_0061101 neuroendocrine cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a neuroendocrine cell of the stomach epithelium. http://purl.obolibrary.org/obo/GO_0061104 adrenal chromaffin cell differentiation http://purl.obolibrary.org/obo/GO_0061101 neuroendocrine cell differentiation The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of an adrenal chromaffin cell. An adrenal chromaffin cell is a neuroendocrine cell that stores epinephrine secretory vesicles. http://purl.obolibrary.org/obo/GO_0061105 regulation of stomach neuroendocrine cell differentiation http://purl.obolibrary.org/obo/GO_0045664 regulation of neuron differentiation Any process that modulates the rate, frequency or extent of the differentiation of a neuroendocrine cell in the stomach. http://purl.obolibrary.org/obo/GO_0061106 negative regulation of stomach neuroendocrine cell differentiation http://purl.obolibrary.org/obo/GO_0061105 regulation of stomach neuroendocrine cell differentiation Any process that decreases the rate, frequency or extent of the differentiation of a neuroendocrine cell in the stomach. http://purl.obolibrary.org/obo/GO_0061107 seminal vesicle development http://purl.obolibrary.org/obo/GO_0048732 gland development The progression of the seminal vesicle over time, from its formation to the mature structure. The seminal vesicle is a gland that contributes to the production of semen. http://purl.obolibrary.org/obo/GO_0061108 seminal vesicle epithelium development http://purl.obolibrary.org/obo/GO_0060429 epithelium development The progression of the seminal vesicle epithelium over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0061109 dense core granule organization http://purl.obolibrary.org/obo/GO_0033363 secretory granule organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a dense core granule. A dense core granule is a secretory organelle found in endocrine cells. http://purl.obolibrary.org/obo/GO_0061113 pancreas morphogenesis http://purl.obolibrary.org/obo/GO_0009887 animal organ morphogenesis Morphogenesis of the pancreas. Morphogenesis is the process in which anatomical structures are generated and organized. http://purl.obolibrary.org/obo/GO_0061114 branching involved in pancreas morphogenesis http://purl.obolibrary.org/obo/GO_0061138 morphogenesis of a branching epithelium The process in which the branches of the pancreas are generated and organized. http://purl.obolibrary.org/obo/GO_0061117 negative regulation of heart growth http://purl.obolibrary.org/obo/GO_0060420 regulation of heart growth Any process that decreases the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart. http://purl.obolibrary.org/obo/GO_0061130 pancreatic bud formation http://purl.obolibrary.org/obo/GO_0061114 branching involved in pancreas morphogenesis The morphogenetic process in which the foregut region specified to become the pancreas forms a bud. http://purl.obolibrary.org/obo/GO_0061140 lung secretory cell differentiation http://purl.obolibrary.org/obo/GO_0060487 lung epithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a lung secretory cell. A lung secretory cell is a specialized epithelial cell of the lung that contains large secretory granules in its apical part. http://purl.obolibrary.org/obo/GO_0061141 lung ciliated cell differentiation http://purl.obolibrary.org/obo/GO_0060487 lung epithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a lung ciliated cell. A lung ciliated cell is a specialized lung epithelial cell that contains cilia for moving substances released from lung secretory cells. http://purl.obolibrary.org/obo/GO_0061146 Peyer's patch morphogenesis http://purl.obolibrary.org/obo/GO_0048729 tissue morphogenesis The process in which a Peyer's patch is generated and organized. Peyer's patches are typically found as nodules associated with gut epithelium with distinct internal structures including B- and T-zones for the activation of lymphocytes. http://purl.obolibrary.org/obo/GO_0061147 endocardial endothelium development http://purl.obolibrary.org/obo/GO_0003158 endothelium development The progression of the endocardial endothelium over time, from its initial formation to the mature structure. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers. http://purl.obolibrary.org/obo/GO_0061148 extracellular matrix organization involved in endocardium development http://purl.obolibrary.org/obo/GO_0030198 extracellular matrix organization A process which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix of the endocardium. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers. http://purl.obolibrary.org/obo/GO_0061152 trachea submucosa development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the trachea submucosa over time from its formation to the mature structure. The trachea submucosa is made up of the glands and elastic tissue that lie under the mucosa in the trachea. http://purl.obolibrary.org/obo/GO_0061153 trachea gland development http://purl.obolibrary.org/obo/GO_0048732 gland development The progression of a trachea gland over time, from its formation to the mature structure. Trachea glands are found under the mucus of the trachea and secrete mucus, and agents that help protect the lung from injury and infection. http://purl.obolibrary.org/obo/GO_0061154 endothelial tube morphogenesis http://purl.obolibrary.org/obo/GO_0060562 epithelial tube morphogenesis The process in which the anatomical structures of a tube are generated and organized from an endothelium. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells. http://purl.obolibrary.org/obo/GO_0061155 pulmonary artery endothelial tube morphogenesis http://purl.obolibrary.org/obo/GO_0061154 endothelial tube morphogenesis The process in which the anatomical structures of a tube are generated and organized from the pulmonary artery endothelium. An pulmonary artery endothelium is an epithelium that lines the pulmonary artery. http://purl.obolibrary.org/obo/GO_0061156 pulmonary artery morphogenesis http://purl.obolibrary.org/obo/GO_0048844 artery morphogenesis The process in which the anatomical structures of the pulmonary artery are generated and organized. The pulmonary artery is the artery that carries blood from the heart to the lungs. http://purl.obolibrary.org/obo/GO_0061168 regulation of hair follicle placode formation http://purl.obolibrary.org/obo/GO_0022603 regulation of anatomical structure morphogenesis Any process that modulates the rate, frequency, or extent of hair follicle placode formation, the developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud. http://purl.obolibrary.org/obo/GO_0061169 positive regulation of hair placode formation http://purl.obolibrary.org/obo/GO_0061168 regulation of hair follicle placode formation Any process that increases the rate, frequency, or extent of hair follicle placode formation, the developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud. http://purl.obolibrary.org/obo/GO_0061170 negative regulation of hair follicle placode formation http://purl.obolibrary.org/obo/GO_0061168 regulation of hair follicle placode formation Any process that decreases the rate, frequency, or extent of hair follicle placode formation, the developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud. http://purl.obolibrary.org/obo/GO_0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus http://purl.obolibrary.org/obo/GO_0061178 regulation of insulin secretion involved in cellular response to glucose stimulus Any process that decreases the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose. http://purl.obolibrary.org/obo/GO_0061181 regulation of chondrocyte development http://purl.obolibrary.org/obo/GO_0060284 regulation of cell development Any process that modulates the rate, frequency, or extent of the process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate. http://purl.obolibrary.org/obo/GO_0061182 negative regulation of chondrocyte development http://purl.obolibrary.org/obo/GO_0061181 regulation of chondrocyte development Any process that decreases the rate, frequency, or extent of the process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate. http://purl.obolibrary.org/obo/GO_0061183 regulation of dermatome development http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin. http://purl.obolibrary.org/obo/GO_0061184 positive regulation of dermatome development http://purl.obolibrary.org/obo/GO_0061183 regulation of dermatome development Any process that increases the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin. http://purl.obolibrary.org/obo/GO_0061185 negative regulation of dermatome development http://purl.obolibrary.org/obo/GO_0061183 regulation of dermatome development Any process that decreases the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin. http://purl.obolibrary.org/obo/GO_0061189 positive regulation of sclerotome development http://purl.obolibrary.org/obo/GO_0061190 regulation of sclerotome development Any process that increases the rate, frequency, or extent of the progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra. http://purl.obolibrary.org/obo/GO_0061190 regulation of sclerotome development http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the rate, frequency, or extent of the progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra. http://purl.obolibrary.org/obo/GO_0061193 taste bud development http://purl.obolibrary.org/obo/GO_0007423 sensory organ development The progression of the taste bud over time, from its formation to the mature state. The taste bud is a specialized area of the tongue that contains taste receptors. http://purl.obolibrary.org/obo/GO_0061194 taste bud morphogenesis http://purl.obolibrary.org/obo/GO_0090596 sensory organ morphogenesis The process in which the anatomical structures of the taste bud are generated and organized. The taste bud is a specialized area of the tongue that contains taste receptors. http://purl.obolibrary.org/obo/GO_0061195 taste bud formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The developmental process pertaining to the initial formation of the taste bud from unspecified parts. The taste bud is a specialized area of the tongue that contains taste receptors. http://purl.obolibrary.org/obo/GO_0061205 paramesonephric duct development http://purl.obolibrary.org/obo/GO_0003006 developmental process involved in reproduction The process whose specific outcome is the progression of the paramesonephric duct over time, from its formation to the mature structure. Mullerian ducts (or paramesonephric ducts) are paired ducts of the embryo that run down the lateral sides of the urogenital ridge and terminate at the mullerian eminence in the primitive urogenital sinus. In the female, they will develop to form the fallopian tubes, uterus, cervix, and the upper portion of the vagina; in the male, they are lost. These ducts are made of tissue of mesodermal origin. http://purl.obolibrary.org/obo/GO_0061206 mesonephros morphogenesis http://purl.obolibrary.org/obo/GO_0060993 kidney morphogenesis The process in which the anatomical structures of the mesonephros are generated and organized. http://purl.obolibrary.org/obo/GO_0061211 mesonephric collecting duct development http://purl.obolibrary.org/obo/GO_0072044 collecting duct development The process whose specific outcome is the progression of a collecting duct in the mesonephros over time, from its formation to the mature structure. The collecting duct regulates water, electrolyte and acid-base balance. The collecting duct is the final common path through which urine flows before entering the ureter and then emptying into the bladder. http://purl.obolibrary.org/obo/GO_0061212 mesonephric juxtaglomerular apparatus development http://purl.obolibrary.org/obo/GO_0072051 juxtaglomerular apparatus development The process whose specific outcome is the progression of the juxtaglomerular apparatus in the mesonephros over time, from its formation to the mature structure. The juxtaglomerular apparatus is an anatomical structure which consists of juxtaglomerular cells, extraglomerular mesangial cells and the macula densa. The juxtaglomerular apparatus lies adjacent to the glomerulus and regulates kidney function by maintaining the blood flow to the kidney and the filtration rate. http://purl.obolibrary.org/obo/GO_0061213 positive regulation of mesonephros development http://purl.obolibrary.org/obo/GO_0090184 positive regulation of kidney development Any process that increases the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine. http://purl.obolibrary.org/obo/GO_0061214 mesonephric smooth muscle tissue development http://purl.obolibrary.org/obo/GO_0072194 kidney smooth muscle tissue development The process whose specific outcome is the progression of smooth muscle in the mesonephros over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0061215 mesonephric nephron development http://purl.obolibrary.org/obo/GO_0072006 nephron development The process whose specific outcome is the progression of a nephron in the mesonephros over time, from its formation to the mature structure. A nephron is the functional unit of the kidney. http://purl.obolibrary.org/obo/GO_0061217 regulation of mesonephros development http://purl.obolibrary.org/obo/GO_0090183 regulation of kidney development Any process that modulates the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine. http://purl.obolibrary.org/obo/GO_0061218 negative regulation of mesonephros development http://purl.obolibrary.org/obo/GO_0090185 negative regulation of kidney development Any process that decreases the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine. http://purl.obolibrary.org/obo/GO_0061219 mesonephric mesenchyme development http://purl.obolibrary.org/obo/GO_0072074 kidney mesenchyme development The biological process whose specific outcome is the progression of a mesonephric mesenchyme from an initial condition to its mature state. This process begins with the formation of mesonephric mesenchyme and ends with the mature structure. Mesonephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the mesonephros. http://purl.obolibrary.org/obo/GO_0061220 mesonephric macula densa development http://purl.obolibrary.org/obo/GO_0072024 macula densa development The process whose specific outcome is the progression of the mesonephric macula densa over time, from its formation to the mature structure. The mesonephric macula densa is an area of specialized cells in the distal tubule of the mesonephros that makes contact with the vascular pole of the glomerulus. http://purl.obolibrary.org/obo/GO_0061221 mesonephric mesenchyme morphogenesis http://purl.obolibrary.org/obo/GO_0072131 kidney mesenchyme morphogenesis The process in which the anatomical structures of a mesonephric mesenchymal tissue are generated and organized. Mesonephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the mesonephros. http://purl.obolibrary.org/obo/GO_0061224 mesonephric glomerulus development http://purl.obolibrary.org/obo/GO_0032835 glomerulus development The progression of the mesonephric glomerulus over time from its initial formation until its mature state. The mesonephric glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the mature vertebrate kidney, or mesonephros. http://purl.obolibrary.org/obo/GO_0061228 mesonephric nephron morphogenesis http://purl.obolibrary.org/obo/GO_0072028 nephron morphogenesis The process in which the anatomical structures of the mesonephric nephron are generated and organized. A mesonephric nephron is the functional unit of the mesonephros. http://purl.obolibrary.org/obo/GO_0061231 mesonephric glomerulus vasculature development http://purl.obolibrary.org/obo/GO_0072012 glomerulus vasculature development The biological process whose specific outcome is the progression of a mesonephric glomerulus vasculature from an initial condition to its mature state. This process begins with the formation of the mesonephric glomerulus vasculature and ends with the mature structure. The mesonephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the mesonephric glomerulus. http://purl.obolibrary.org/obo/GO_0061232 mesonephric glomerular epithelium development http://purl.obolibrary.org/obo/GO_0072010 glomerular epithelium development The process whose specific outcome is the progression of the mesonephric glomerular epithelium over time, from its formation to the mature structure. The mesonephric glomerular epithelium is an epithelial tissue that covers the outer surfaces of the glomerulus in the mesonephros. The mesonephric glomerular epithelium consists of both parietal and visceral epithelium. Mesonephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the mesonephros. http://purl.obolibrary.org/obo/GO_0061234 mesonephric glomerulus morphogenesis http://purl.obolibrary.org/obo/GO_0072102 glomerulus morphogenesis The process in which the anatomical structures of the mesonephric glomerulus are generated and organized. The mesonephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate mesonephros. http://purl.obolibrary.org/obo/GO_0061236 mesonephric comma-shaped body morphogenesis http://purl.obolibrary.org/obo/GO_0072049 comma-shaped body morphogenesis The process in which the mesonephric comma-shaped body is generated and organized. The mesonephric comma-shaped body is the precursor structure to the mesonephric S-shaped body that contributes to the morphogenesis of a nephron in the mesonephros. http://purl.obolibrary.org/obo/GO_0061240 mesonephric nephron tubule morphogenesis http://purl.obolibrary.org/obo/GO_0072171 mesonephric tubule morphogenesis The process in which the anatomical structures of a mesonephric nephron tubule are generated and organized. A mesonephric nephron tubule is an epithelial tube that is part of the mesonephric nephron, the functional part of the mesonephros. http://purl.obolibrary.org/obo/GO_0061241 mesonephric nephron epithelium development http://purl.obolibrary.org/obo/GO_0072163 mesonephric epithelium development The process whose specific outcome is the progression of the mesonephric nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The mesonephric nephron epithelium is a tissue that covers the surface of a nephron in the mesonephros. http://purl.obolibrary.org/obo/GO_0061242 mesonephric nephron tubule development http://purl.obolibrary.org/obo/GO_0061241 mesonephric nephron epithelium development The progression of a mesonephric nephron tubule over time, from its initial formation to the mature structure. A mesonephric nephron tubule is an epithelial tube that is part of the mesonephric nephron, the functional part of the mesonephros. http://purl.obolibrary.org/obo/GO_0061243 mesonephric renal vesicle morphogenesis http://purl.obolibrary.org/obo/GO_0072077 renal vesicle morphogenesis The process in which the anatomical structures of the mesonephric renal vesicle are generated and organized. The renal vesicle is the primordial structure of the mesonephric nephron epithelium, and is formed by the condensation of mesenchymal cells. http://purl.obolibrary.org/obo/GO_0061244 mesonephric S-shaped body morphogenesis http://purl.obolibrary.org/obo/GO_0072050 S-shaped body morphogenesis The process in which the mesonephric S-shaped body is generated and organized. The mesonephric S-shaped body is the successor of the mesonephric comma-shaped body that contributes to the morphogenesis of a nephron in the mesonephros. http://purl.obolibrary.org/obo/GO_0061247 mesonephric glomerular mesangium development http://purl.obolibrary.org/obo/GO_0072109 glomerular mesangium development The process whose specific outcome is the progression of the mesonephric glomerular mesangium over time, from its formation to the mature structure. The mesonephric glomerular mesangium is the thin membrane connective tissue composed of mesangial cells in the mesonephros, which helps to support the capillary loops in a renal glomerulus. http://purl.obolibrary.org/obo/GO_0061248 mesonephric glomerulus vasculature morphogenesis http://purl.obolibrary.org/obo/GO_0072103 glomerulus vasculature morphogenesis The process in which the anatomical structures of the mesonephric glomerulus vasculature are generated and organized. The mesonephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the mesonephric glomerulus. http://purl.obolibrary.org/obo/GO_0061249 mesonephric glomerular capillary formation http://purl.obolibrary.org/obo/GO_0072104 glomerular capillary formation The process that gives rise to a mesonephric glomerular capillary. This process pertains to the initial formation of a structure from unspecified parts. http://purl.obolibrary.org/obo/GO_0061250 mesonephric glomerular epithelial cell differentiation http://purl.obolibrary.org/obo/GO_0072311 glomerular epithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a mesonephric glomerular epithelial cell. Mesonephric glomerular epithelial cells are specialized epithelial cells that form part of the mesonephric glomerulus; there are two types, mesonephric glomerular parietal epithelial cells and mesonephric glomerular visceral epithelial cells. http://purl.obolibrary.org/obo/GO_0061251 mesonephric glomerular epithelial cell development http://purl.obolibrary.org/obo/GO_0072310 glomerular epithelial cell development The process whose specific outcome is the progression of a mesonephric glomerular epithelial cell over time, from its formation to the mature structure. Mesonephric glomerular epithelial cells are specialized epithelial cells that form part of the mesonephric glomerulus; there are two types, mesonephric glomerular parietal epithelial cells and mesonephric glomerular visceral epithelial cells. http://purl.obolibrary.org/obo/GO_0061256 mesonephric podocyte differentiation http://purl.obolibrary.org/obo/GO_0072112 podocyte differentiation The process in which a relatively unspecialized cell acquires specialized features of a mesonephric glomerular visceral epithelial cell. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the mesonephros. http://purl.obolibrary.org/obo/GO_0061257 mesonephric podocyte development http://purl.obolibrary.org/obo/GO_0072015 podocyte development The process whose specific outcome is the progression of a mesonephric glomerular visceral epithelial cell over time, from its formation to the mature structure. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the mesonephros. http://purl.obolibrary.org/obo/GO_0061262 mesonephric renal vesicle formation http://purl.obolibrary.org/obo/GO_0072033 renal vesicle formation The developmental process pertaining to the initial formation of the mesonephros. http://purl.obolibrary.org/obo/GO_0061265 mesonephric nephron tubule epithelial cell differentiation http://purl.obolibrary.org/obo/GO_0072160 nephron tubule epithelial cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the mesonephric nephron tubule as it progresses from its formation to the mature state. http://purl.obolibrary.org/obo/GO_0061272 mesonephric connecting tubule development http://purl.obolibrary.org/obo/GO_0072027 connecting tubule development The process whose specific outcome is the progression of the mesonephric connecting tubule over time, from its formation to the mature structure. The mesonephric connecting tubule is a tubular segment of the mesonephric nephron; it connects the distal tubule to the collecting duct in the mesonephros. http://purl.obolibrary.org/obo/GO_0061273 mesonephric distal tubule morphogenesis http://purl.obolibrary.org/obo/GO_0061240 mesonephric nephron tubule morphogenesis The process in which the anatomical structures of a mesonephric distal tubule are generated and organized. The mesonephric distal tubule is a mesonephric nephron tubule that begins at the macula densa and extends to the mesonephric connecting tubule. http://purl.obolibrary.org/obo/GO_0061274 mesonephric distal tubule development http://purl.obolibrary.org/obo/GO_0061242 mesonephric nephron tubule development The process whose specific outcome is the progression of the mesonephric distal tubule over time, from its formation to the mature structure. The mesonephric distal tubule is a mesonephric nephron tubule that begins at the terminal segment of the proximal tubule and ends at the mesonephric connecting tubule. http://purl.obolibrary.org/obo/GO_0061275 mesonephric proximal tubule development http://purl.obolibrary.org/obo/GO_0061242 mesonephric nephron tubule development The progression of the mesonephric proximal tubule over time, from its formation to the mature structure. The mesonephric proximal tubule extends from the capsule to the distal tubule. http://purl.obolibrary.org/obo/GO_0061276 mesonephric proximal tubule morphogenesis http://purl.obolibrary.org/obo/GO_0061240 mesonephric nephron tubule morphogenesis The process in which the anatomical structures of a mesonephric proximal tubule are generated and organized. The mesonephric proximal tubule extends from the capsule to the distal tubule. http://purl.obolibrary.org/obo/GO_0061277 mesonephric nephron tubule formation http://purl.obolibrary.org/obo/GO_0072172 mesonephric tubule formation The developmental process pertaining to the initial formation of a mesonephric nephron tubule from unspecified parts. A mesonephric nephron tubule is an epithelial tube that is part of a nephron in the mesonephros. http://purl.obolibrary.org/obo/GO_0061285 mesonephric capsule development http://purl.obolibrary.org/obo/GO_0072127 renal capsule development The progression of the mesonephric capsule over time, from its formation to the mature structure. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue. http://purl.obolibrary.org/obo/GO_0061286 mesonephric capsule morphogenesis http://purl.obolibrary.org/obo/GO_0072128 renal capsule morphogenesis The process in which the anatomical structures of the mesonephric capsule are generated and organized. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. http://purl.obolibrary.org/obo/GO_0061287 mesonephric capsule formation http://purl.obolibrary.org/obo/GO_0072129 renal capsule formation The developmental process pertaining to the initial formation of a mesonephric capsule from unspecified parts. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. http://purl.obolibrary.org/obo/GO_0061298 retina vasculature development in camera-type eye http://purl.obolibrary.org/obo/GO_0001944 vasculature development The process whose specific outcome is the progression of the vasculature of the retina over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0061299 retina vasculature morphogenesis in camera-type eye http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the vasculature of the retina is generated and organized. http://purl.obolibrary.org/obo/GO_0061300 cerebellum vasculature development http://purl.obolibrary.org/obo/GO_0001944 vasculature development The process whose specific outcome is the progression of the vasculature of the cerebellum over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0061301 cerebellum vasculature morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the vasculature of the cerebellum is generated and organized. http://purl.obolibrary.org/obo/GO_0061304 retinal blood vessel morphogenesis http://purl.obolibrary.org/obo/GO_0061299 retina vasculature morphogenesis in camera-type eye The process whose specific outcome is the progression of a blood vessel of the retina over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0061307 cardiac neural crest cell differentiation involved in heart development http://purl.obolibrary.org/obo/GO_0014033 neural crest cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a cardiac neural crest cell that will migrate to the heart and contribute to its development. Cardiac neural crest cells are specialized cells that migrate toward the heart from the third, fourth and sixth pharyngeal arches. http://purl.obolibrary.org/obo/GO_0061318 renal filtration cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a renal filtration cell. Renal filtration cells are specialized cells of the renal system that filter fluids by charge, size or both. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. http://purl.obolibrary.org/obo/GO_0061319 nephrocyte differentiation http://purl.obolibrary.org/obo/GO_0061318 renal filtration cell differentiation The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a nephrocyte. A nephrocyte is an insect renal cell that filters hemolymph. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. http://purl.obolibrary.org/obo/GO_0061322 disseminated nephrocyte differentiation http://purl.obolibrary.org/obo/GO_0061319 nephrocyte differentiation The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a disseminated nephrocyte. A disseminated nephrocyte is an insect renal cell that filters hemolymph and is found at scattered locations in the fat body or other tissues. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. http://purl.obolibrary.org/obo/GO_0061325 cell proliferation involved in outflow tract morphogenesis http://purl.obolibrary.org/obo/GO_0061323 cell proliferation involved in heart morphogenesis The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to the shaping of the outflow tract. http://purl.obolibrary.org/obo/GO_0061326 renal tubule development http://purl.obolibrary.org/obo/GO_0060429 epithelium development The progression of the renal tubule over time from its formation to the mature form. A renal tubule is a tube that filters, re-absorbs and secretes substances to rid an organism of waste and to play a role in fluid homeostasis. http://purl.obolibrary.org/obo/GO_0061330 Malpighian tubule stellate cell differentiation http://purl.obolibrary.org/obo/GO_0030855 epithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a Malpighian tubule stellate cell. A Malpighian tubule stellate cell is a specialized epithelial secretory cell that moves chloride ions and water across the tubule epithelium. http://purl.obolibrary.org/obo/GO_0061331 epithelial cell proliferation involved in Malpighian tubule morphogenesis http://purl.obolibrary.org/obo/GO_2001013 epithelial cell proliferation involved in renal tubule morphogenesis The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population and contributing to the shaping of a Malpighian tubule. http://purl.obolibrary.org/obo/GO_0061332 Malpighian tubule bud morphogenesis http://purl.obolibrary.org/obo/GO_0060572 morphogenesis of an epithelial bud The morphogenetic process in which a bud forms from the embryonic hindgut tube to form the Malpighian tubule. A bud is a protrusion that forms from the tube by localized changes in cell shape and position. http://purl.obolibrary.org/obo/GO_0061334 cell rearrangement involved in Malpighian tubule morphogenesis http://purl.obolibrary.org/obo/GO_0016477 cell migration The movement of an epithelial cell with respect to other epithelial cells that contributes to the shaping of the Malpighian tubule. http://purl.obolibrary.org/obo/GO_0061336 cell morphogenesis involved in Malpighian tubule morphogenesis http://purl.obolibrary.org/obo/GO_0000902 cell morphogenesis The shape change of an epithelial cell from a columnar to squamous cell morphology that contributes to the shaping of the Malpighian tubule. http://purl.obolibrary.org/obo/GO_0061337 cardiac conduction http://purl.obolibrary.org/obo/GO_0008016 regulation of heart contraction Transfer of an organized electrical impulse across the heart to coordinate the contraction of cardiac muscles. The process begins with generation of an action potential (in the sinoatrial node (SA) in humans) and ends with a change in the rate, frequency, or extent of the contraction of the heart muscles. http://purl.obolibrary.org/obo/GO_0061344 regulation of cell adhesion involved in heart morphogenesis http://purl.obolibrary.org/obo/GO_0030155 regulation of cell adhesion Any process that modulates the extent of cell adhesion contributing to the shaping of the heart. http://purl.obolibrary.org/obo/GO_0061352 cell chemotaxis involved in Malpighian tubule morphogenesis http://purl.obolibrary.org/obo/GO_0061334 cell rearrangement involved in Malpighian tubule morphogenesis The directed movement of the outgrowing Malpighian tubule guided by specific chemical cues/signals. Movement may be towards a guidance cue (positive chemotaxis) or away from it (negative chemotaxis). Guidance contributes to the final positioning of the tubule. http://purl.obolibrary.org/obo/GO_0061360 optic chiasma development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The developmental process pertaining to the progression of the optic chiasm from its initial formation to the mature structure. The process begins when the pathfinding of the axons of the developing optic nerve cause some axons to cross at the midline of the brain and ends when the axons are mature. http://purl.obolibrary.org/obo/GO_0061370 testosterone biosynthetic process http://purl.obolibrary.org/obo/GO_0042181 ketone biosynthetic process The chemical reactions and pathways resulting in the formation of testosterone, an androgen having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-4 C-5. http://purl.obolibrary.org/obo/GO_0061377 mammary gland lobule development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the mammary gland lobule over time, from its formation to the mature structure. A mammary gland lobule is a small rounded projection of the mammary gland. http://purl.obolibrary.org/obo/GO_0061382 Malpighian tubule tip cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a Malpighian tubule tip cell. A Malpighian tubule tip cell is a mitogenic signaling cell that controls the proliferation of its neighboring cells. http://purl.obolibrary.org/obo/GO_0061383 trabecula morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process of shaping a trabecula in an organ. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue. http://purl.obolibrary.org/obo/GO_0061437 renal system vasculature development http://purl.obolibrary.org/obo/GO_0001944 vasculature development The process whose specific outcome is the progression of vasculature of the renal system over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0061438 renal system vasculature morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the renal system vasculature is generated and organized. Morphogenesis pertains to the creation of form. http://purl.obolibrary.org/obo/GO_0061439 kidney vasculature morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the kidney vasculature is generated and organized. Morphogenesis pertains to the creation of form. http://purl.obolibrary.org/obo/GO_0061440 kidney vasculature development http://purl.obolibrary.org/obo/GO_0061437 renal system vasculature development The process whose specific outcome is the progression of the vasculature of the kidney over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0061441 renal artery morphogenesis http://purl.obolibrary.org/obo/GO_0048844 artery morphogenesis The process in which the anatomical structure of a renal artery is generated and organized. Renal arteries supply the kidneys with blood. http://purl.obolibrary.org/obo/GO_0061449 olfactory bulb tufted cell development http://purl.obolibrary.org/obo/GO_0021884 forebrain neuron development The process whose specific outcome is the progression of an olfactory bulb tufted cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. http://purl.obolibrary.org/obo/GO_0061450 trophoblast cell migration http://purl.obolibrary.org/obo/GO_0001667 ameboidal-type cell migration Trophoblast cell migration that is accomplished by extension and retraction of a pseudopodium. Trophoblast cells line the outside of the blastocyst. http://purl.obolibrary.org/obo/GO_0061451 retrotrapezoid nucleus development http://purl.obolibrary.org/obo/GO_0048857 neural nucleus development The progression of the retrotrapezoid nucleus (RTN) over time from it's initial formation to its mature state. The retrotrapezoid nucleus is a group of neurons in the rostral medulla, which are responsible regulating respiration. http://purl.obolibrary.org/obo/GO_0061452 retrotrapezoid nucleus neuron differentiation http://purl.obolibrary.org/obo/GO_0021953 central nervous system neuron differentiation The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the retrotrapezoid nucleus. http://purl.obolibrary.org/obo/GO_0061453 interstitial cell of Cajal differentiation http://purl.obolibrary.org/obo/GO_0060575 intestinal epithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of an interstitial cell of Cajal. An interstitial cell of Cajal is an intestinal neuroepithelial cell that serves as a pacemaker to trigger gut contraction. http://purl.obolibrary.org/obo/GO_0061454 release of sequestered calcium ion into cytosol by Golgi http://purl.obolibrary.org/obo/GO_0051209 release of sequestered calcium ion into cytosol The directed movement of calcium ions (Ca2+) out of the Golgi apparatus into the cytosol. http://purl.obolibrary.org/obo/GO_0061470 T follicular helper cell differentiation http://purl.obolibrary.org/obo/GO_0042093 T-helper cell differentiation The process in which a relatively unspecialized T cell acquires specialized features of a mature T follicular helper cell. http://purl.obolibrary.org/obo/GO_0061484 hematopoietic stem cell homeostasis http://purl.obolibrary.org/obo/GO_0048872 homeostasis of number of cells Any biological process involved in the maintenance of the steady-state number of hematopoietic stem cells within a population of cells. http://purl.obolibrary.org/obo/GO_0061485 memory T cell proliferation http://purl.obolibrary.org/obo/GO_0042098 T cell proliferation The expansion of a memory T cell population by cell division. http://purl.obolibrary.org/obo/GO_0061512 protein localization to cilium http://purl.obolibrary.org/obo/GO_0033365 protein localization to organelle A process in which a protein is transported to, or maintained in, a location within a cilium. http://purl.obolibrary.org/obo/GO_0061519 macrophage homeostasis http://purl.obolibrary.org/obo/GO_0002262 myeloid cell homeostasis The process of regulating the proliferation and elimination of macrophage cells such that the total number of myeloid cells within a whole or part of an organism is stable over time in the absence of an outside stimulus. http://purl.obolibrary.org/obo/GO_0061520 Langerhans cell differentiation http://purl.obolibrary.org/obo/GO_0043011 myeloid dendritic cell differentiation The process in which a precursor cell type acquires the specialized features of a Langerhans cell. http://purl.obolibrary.org/obo/GO_0061521 hepatic stellate cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a hepatic stellate cell. http://purl.obolibrary.org/obo/GO_0061523 cilium disassembly http://purl.obolibrary.org/obo/GO_1903008 organelle disassembly A cellular process that results in the breakdown of a cilium. http://purl.obolibrary.org/obo/GO_0061524 central canal development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the formation of the central canal of the spinal cord from its formation to the mature structure. The central canal is a spinal cord structure that is part of the ventricular system and is filled with cerebral-spinal fluid and runs the length of the spinal cord. http://purl.obolibrary.org/obo/GO_0061527 dopamine secretion, neurotransmission http://purl.obolibrary.org/obo/GO_0099124 axonal dopamine secretion The regulated release of dopamine by a cell in which the dopamine acts as a neurotransmitter. http://purl.obolibrary.org/obo/GO_0061533 norepinephrine secretion, neurotransmission http://purl.obolibrary.org/obo/GO_0048243 norepinephrine secretion The regulated release of norepinephrine by a cell, in which the norepinephrine acts as a neurotransmitter. http://purl.obolibrary.org/obo/GO_0061534 gamma-aminobutyric acid secretion, neurotransmission http://purl.obolibrary.org/obo/GO_0014051 gamma-aminobutyric acid secretion The regulated release of gamma-aminobutyric acid by a cell, in which the gamma-aminobutyric acid acts as a neurotransmitter. http://purl.obolibrary.org/obo/GO_0061535 glutamate secretion, neurotransmission http://purl.obolibrary.org/obo/GO_0051938 L-glutamate import The controlled release of glutamate by a cell, in which the glutamate acts as a neurotransmitter. http://purl.obolibrary.org/obo/GO_0061536 glycine secretion http://purl.obolibrary.org/obo/GO_0015816 glycine transport The controlled release of glycine by a cell. http://purl.obolibrary.org/obo/GO_0061537 glycine secretion, neurotransmission http://purl.obolibrary.org/obo/GO_0061536 glycine secretion The controlled release of glycine by a cell, in which glycine acts as a neurotransmitter. http://purl.obolibrary.org/obo/GO_0061538 histamine secretion, neurotransmission http://purl.obolibrary.org/obo/GO_0015807 L-amino acid transport The controlled release of histamine by a cell, in which the histamine acts as a neurotransmitter. http://purl.obolibrary.org/obo/GO_0061544 peptide secretion, neurotransmission http://purl.obolibrary.org/obo/GO_0007269 neurotransmitter secretion The controlled release of a peptide from a cell in which the peptide acts as a neurotransmitter. http://purl.obolibrary.org/obo/GO_0061548 ganglion development http://purl.obolibrary.org/obo/GO_0009888 tissue development The process whose specific outcome is the progression of a ganglion over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0061549 sympathetic ganglion development http://purl.obolibrary.org/obo/GO_0061548 ganglion development The process whose specific outcome is the progression of a sympathetic ganglion over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0061551 trigeminal ganglion development http://purl.obolibrary.org/obo/GO_0061550 cranial ganglion development The process whose specific outcome is the progression of a trigeminal ganglion over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0061552 ganglion morphogenesis http://purl.obolibrary.org/obo/GO_0048729 tissue morphogenesis The process in which the anatomical structures of ganglion are generated and organized. http://purl.obolibrary.org/obo/GO_0061553 ganglion maturation http://purl.obolibrary.org/obo/GO_0071695 anatomical structure maturation A developmental process, independent of morphogenetic (shape) change, that is required for ganglion to attain its fully functional state. http://purl.obolibrary.org/obo/GO_0061554 ganglion formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process that gives rise to ganglion. This process pertains to the initial formation of a structure from unspecified parts. http://purl.obolibrary.org/obo/GO_0061556 trigeminal ganglion morphogenesis http://purl.obolibrary.org/obo/GO_0061559 cranial ganglion morphogenesis The process in which the anatomical structure of a trigeminal ganglion is generated and organized. http://purl.obolibrary.org/obo/GO_0061557 trigeminal ganglion maturation http://purl.obolibrary.org/obo/GO_0061558 cranial ganglion maturation A developmental process, independent of morphogenetic (shape) change, that is required for a trigeminal ganglion to attain its fully functional state. http://purl.obolibrary.org/obo/GO_0061558 cranial ganglion maturation http://purl.obolibrary.org/obo/GO_0061553 ganglion maturation A developmental process, independent of morphogenetic (shape) change, that is required for a cranial ganglion to attain its fully functional state. http://purl.obolibrary.org/obo/GO_0061559 cranial ganglion morphogenesis http://purl.obolibrary.org/obo/GO_0061552 ganglion morphogenesis The process in which the anatomical structure of a cranial ganglion is generated and organized. http://purl.obolibrary.org/obo/GO_0061560 cranial ganglion formation http://purl.obolibrary.org/obo/GO_0061554 ganglion formation The process that gives rise to a cranial ganglion. This process pertains to the initial formation of a structure from unspecified parts. http://purl.obolibrary.org/obo/GO_0061561 trigeminal ganglion formation http://purl.obolibrary.org/obo/GO_0061560 cranial ganglion formation The process that gives rise to the trigeminal ganglion. This process pertains to the initial formation of a structure from unspecified parts. http://purl.obolibrary.org/obo/GO_0061580 colon epithelial cell migration http://purl.obolibrary.org/obo/GO_0061582 intestinal epithelial cell migration The orderly movement of a colonic epithelial cell from one site to another, often during the development of a multicellular organism. http://purl.obolibrary.org/obo/GO_0061581 corneal epithelial cell migration http://purl.obolibrary.org/obo/GO_0010631 epithelial cell migration The orderly movement of a corneal epithelial cell from one site to another, often during the development of a multicellular organism. http://purl.obolibrary.org/obo/GO_0061582 intestinal epithelial cell migration http://purl.obolibrary.org/obo/GO_0010631 epithelial cell migration The orderly movement of an intestinal epithelial cell from one site to another, often during the development of a multicellular organism. http://purl.obolibrary.org/obo/GO_0061584 orexin secretion http://purl.obolibrary.org/obo/GO_0002790 peptide secretion The controlled release of orexin from a cell or a tissue. http://purl.obolibrary.org/obo/GO_0061585 orexin secretion, neurotransmission http://purl.obolibrary.org/obo/GO_0061584 orexin secretion The controlled release of orexin from a cell in which orexin acts as a neurotransmitter. http://purl.obolibrary.org/obo/GO_0061626 pharyngeal arch artery morphogenesis http://purl.obolibrary.org/obo/GO_0048844 artery morphogenesis The process in which the anatomical structures of a pharyngeal arch artery is generated and organized. The pharyngeal arch arteries are a series of six paired embryological vascular structures, the development of which give rise to several major arteries, such as the stapedial artery, the middle meningeal artery, the internal carotid artery and the pulmonary artery. http://purl.obolibrary.org/obo/GO_0061629 RNA polymerase II-specific DNA-binding transcription factor binding http://purl.obolibrary.org/obo/GO_0140297 DNA-binding transcription factor binding Binding to a sequence-specific DNA binding RNA polymerase II transcription factor, any of the factors that interact selectively and non-covalently with a specific DNA sequence in order to modulate transcription. http://purl.obolibrary.org/obo/GO_0061668 mitochondrial ribosome assembly http://purl.obolibrary.org/obo/GO_0042255 ribosome assembly The aggregation, arrangement and bonding together of the mitochondrial ribosome and of its subunits. http://purl.obolibrary.org/obo/GO_0061682 seminal vesicle morphogenesis http://purl.obolibrary.org/obo/GO_0022612 gland morphogenesis The process in which the anatomical structures of a seminal vesicle are generated and organized. http://purl.obolibrary.org/obo/GO_0061725 cytosolic lipolysis http://purl.obolibrary.org/obo/GO_0016042 lipid catabolic process The chemical reactions and pathways resulting in the breakdown of lipid droplets and hydrolysis of stored triglycerides occurring through the orchestrated activation of cytosolic lipases. http://purl.obolibrary.org/obo/GO_0061792 secretory granule maturation http://purl.obolibrary.org/obo/GO_0071695 anatomical structure maturation Steps required to transform an immature secretory vesicle into a mature secretory vesicle. Typically proceeds through homotypic membrane fusion and membrane remodeling. http://purl.obolibrary.org/obo/GO_0061847 response to cholecystokinin http://purl.obolibrary.org/obo/GO_0043434 response to peptide hormone Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cholecystokinin stimulus. http://purl.obolibrary.org/obo/GO_0061848 cellular response to cholecystokinin http://purl.obolibrary.org/obo/GO_0061847 response to cholecystokinin Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cholecystokinin stimulus. http://purl.obolibrary.org/obo/GO_0070050 neuron cellular homeostasis http://purl.obolibrary.org/obo/GO_0019725 cellular homeostasis The cellular homeostatic process that preserves a neuron in a stable, differentiated functional and structural state. http://purl.obolibrary.org/obo/GO_0070051 fibrinogen binding http://purl.obolibrary.org/obo/GO_0044877 protein-containing complex binding Binding to fibrinogen, a highly soluble hexameric glycoprotein complex that is found in blood plasma and is converted to fibrin by thrombin in the coagulation cascade. http://purl.obolibrary.org/obo/GO_0070062 extracellular exosome http://purl.obolibrary.org/obo/GO_1903561 extracellular vesicle A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm. http://purl.obolibrary.org/obo/GO_0070091 glucagon secretion http://purl.obolibrary.org/obo/GO_0030072 peptide hormone secretion The regulated release of glucagon from secretory granules in the A (alpha) cells of the pancreas (islets of Langerhans). http://purl.obolibrary.org/obo/GO_0070092 regulation of glucagon secretion http://purl.obolibrary.org/obo/GO_0090276 regulation of peptide hormone secretion Any process that modulates the frequency, rate or extent of the regulated release of glucagon. http://purl.obolibrary.org/obo/GO_0070093 negative regulation of glucagon secretion http://purl.obolibrary.org/obo/GO_0070092 regulation of glucagon secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of glucagon. http://purl.obolibrary.org/obo/GO_0070094 positive regulation of glucagon secretion http://purl.obolibrary.org/obo/GO_0070092 regulation of glucagon secretion Any process that activates or increases the frequency, rate or extent of the regulated release of glucagon. http://purl.obolibrary.org/obo/GO_0070124 mitochondrial translational initiation http://purl.obolibrary.org/obo/GO_0006413 translational initiation The process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion. This includes the formation of a complex of the ribosome, mRNA, and an initiation complex that contains the first aminoacyl-tRNA. http://purl.obolibrary.org/obo/GO_0070125 mitochondrial translational elongation http://purl.obolibrary.org/obo/GO_0006414 translational elongation The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis in a mitochondrion. http://purl.obolibrary.org/obo/GO_0070126 mitochondrial translational termination http://purl.obolibrary.org/obo/GO_0006415 translational termination The process resulting in the release of a polypeptide chain from the ribosome in a mitochondrion, usually in response to a termination codon (note that mitochondria use variants of the universal genetic code that differ between different taxa). http://purl.obolibrary.org/obo/GO_0070129 regulation of mitochondrial translation http://purl.obolibrary.org/obo/GO_0006417 regulation of translation Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion. http://purl.obolibrary.org/obo/GO_0070130 negative regulation of mitochondrial translation http://purl.obolibrary.org/obo/GO_0070129 regulation of mitochondrial translation Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion. http://purl.obolibrary.org/obo/GO_0070132 regulation of mitochondrial translational initiation http://purl.obolibrary.org/obo/GO_0070129 regulation of mitochondrial translation Any process that modulates the frequency, rate or extent of the process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion. http://purl.obolibrary.org/obo/GO_0070133 negative regulation of mitochondrial translational initiation http://purl.obolibrary.org/obo/GO_0070132 regulation of mitochondrial translational initiation Any process that stops, prevents, or reduces the frequency, rate or extent of the process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion. http://purl.obolibrary.org/obo/GO_0070134 positive regulation of mitochondrial translational initiation http://purl.obolibrary.org/obo/GO_0070132 regulation of mitochondrial translational initiation Any process that activates or increases the frequency, rate or extent of the process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion. http://purl.obolibrary.org/obo/GO_0070170 regulation of tooth mineralization http://purl.obolibrary.org/obo/GO_0070167 regulation of biomineral tissue development Any process that modulates the frequency, rate or extent of tooth mineralization, the deposition of calcium salts in tooth structures. http://purl.obolibrary.org/obo/GO_0070171 negative regulation of tooth mineralization http://purl.obolibrary.org/obo/GO_0070170 regulation of tooth mineralization Any process that stops, prevents, or reduces the frequency, rate or extent of tooth mineralization, the deposition of calcium salts in tooth structures. http://purl.obolibrary.org/obo/GO_0070172 positive regulation of tooth mineralization http://purl.obolibrary.org/obo/GO_0070170 regulation of tooth mineralization Any process that activates or increases the frequency, rate or extent of tooth mineralization, the deposition of calcium salts in tooth structures. http://purl.obolibrary.org/obo/GO_0070199 establishment of protein localization to chromosome http://purl.obolibrary.org/obo/GO_0072594 establishment of protein localization to organelle The directed movement of a protein to a specific location on a chromosome. http://purl.obolibrary.org/obo/GO_0070202 regulation of establishment of protein localization to chromosome http://purl.obolibrary.org/obo/GO_0070201 regulation of establishment of protein localization Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location on a chromosome. http://purl.obolibrary.org/obo/GO_0070232 regulation of T cell apoptotic process http://purl.obolibrary.org/obo/GO_0070228 regulation of lymphocyte apoptotic process Any process that modulates the occurrence or rate of T cell death by apoptotic process. http://purl.obolibrary.org/obo/GO_0070233 negative regulation of T cell apoptotic process http://purl.obolibrary.org/obo/GO_0070232 regulation of T cell apoptotic process Any process that stops, prevents, or reduces the frequency, rate or extent of T cell death by apoptotic process. http://purl.obolibrary.org/obo/GO_0070234 positive regulation of T cell apoptotic process http://purl.obolibrary.org/obo/GO_0070232 regulation of T cell apoptotic process Any process that activates or increases the frequency, rate or extent of T cell death by apoptotic process. http://purl.obolibrary.org/obo/GO_0070242 thymocyte apoptotic process http://purl.obolibrary.org/obo/GO_0070231 T cell apoptotic process Any apoptotic process in a thymocyte, an immature T cell located in the thymus. http://purl.obolibrary.org/obo/GO_0070243 regulation of thymocyte apoptotic process http://purl.obolibrary.org/obo/GO_0070232 regulation of T cell apoptotic process Any process that modulates the occurrence or rate of thymocyte death by apoptotic process. http://purl.obolibrary.org/obo/GO_0070244 negative regulation of thymocyte apoptotic process http://purl.obolibrary.org/obo/GO_0070243 regulation of thymocyte apoptotic process Any process that stops, prevents, or reduces the frequency, rate or extent of thymocyte death by apoptotic process. http://purl.obolibrary.org/obo/GO_0070245 positive regulation of thymocyte apoptotic process http://purl.obolibrary.org/obo/GO_0070243 regulation of thymocyte apoptotic process Any process that activates or increases the frequency, rate or extent of thymocyte death by apoptotic process. http://purl.obolibrary.org/obo/GO_0070246 natural killer cell apoptotic process http://purl.obolibrary.org/obo/GO_0070227 lymphocyte apoptotic process Any apoptotic process in a natural killer cell, a lymphocyte that can spontaneously kill a variety of target cells without prior antigenic activation. http://purl.obolibrary.org/obo/GO_0070247 regulation of natural killer cell apoptotic process http://purl.obolibrary.org/obo/GO_0070228 regulation of lymphocyte apoptotic process Any process that modulates the occurrence or rate of natural killer cell death by apoptotic process. http://purl.obolibrary.org/obo/GO_0070248 negative regulation of natural killer cell apoptotic process http://purl.obolibrary.org/obo/GO_0070247 regulation of natural killer cell apoptotic process Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell death by apoptotic process. http://purl.obolibrary.org/obo/GO_0070249 positive regulation of natural killer cell apoptotic process http://purl.obolibrary.org/obo/GO_0070247 regulation of natural killer cell apoptotic process Any process that activates or increases the frequency, rate or extent of natural killer cell death by apoptotic process. http://purl.obolibrary.org/obo/GO_0070253 somatostatin secretion http://purl.obolibrary.org/obo/GO_0030072 peptide hormone secretion The regulated release of somatostatin from secretory granules in the D cells of the pancreas. http://purl.obolibrary.org/obo/GO_0070254 mucus secretion http://purl.obolibrary.org/obo/GO_0032941 secretion by tissue The regulated release of mucus by the mucosa. Mucus is a viscous slimy secretion consisting of mucins and various inorganic salts dissolved in water, with suspended epithelial cells and leukocytes. The mucosa, or mucous membrane, is the membrane covered with epithelium that lines the tubular organs of the body. Mucins are carbohydrate-rich glycoproteins that have a lubricating and protective function. http://purl.obolibrary.org/obo/GO_0070255 regulation of mucus secretion http://purl.obolibrary.org/obo/GO_0051239 regulation of multicellular organismal process Any process that modulates the frequency, rate or extent of the regulated release of mucus from a cell or a tissue. http://purl.obolibrary.org/obo/GO_0070256 negative regulation of mucus secretion http://purl.obolibrary.org/obo/GO_0070255 regulation of mucus secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of mucus from a cell or a tissue. http://purl.obolibrary.org/obo/GO_0070257 positive regulation of mucus secretion http://purl.obolibrary.org/obo/GO_0070255 regulation of mucus secretion Any process that activates or increases the frequency, rate or extent of the regulated release of mucus from a cell or a tissue. http://purl.obolibrary.org/obo/GO_0070285 pigment cell development http://purl.obolibrary.org/obo/GO_0048468 cell development The process whose specific outcome is the progression of a pigment cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a pigment cell fate. http://purl.obolibrary.org/obo/GO_0070306 lens fiber cell differentiation http://purl.obolibrary.org/obo/GO_0030855 epithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a lens fiber cell, any of the elongated, tightly packed cells that make up the bulk of the mature lens in the camera-type eye. The cytoplasm of a lens fiber cell is devoid of most intracellular organelles including the cell nucleus, and contains primarily crystallins, a group of water-soluble proteins expressed in vary large quantities. http://purl.obolibrary.org/obo/GO_0070307 lens fiber cell development http://purl.obolibrary.org/obo/GO_0002064 epithelial cell development The process whose specific outcome is the progression of a lens fiber cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a lens fiber cell fate. A lens fiber cell is any of the elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye. http://purl.obolibrary.org/obo/GO_0070341 fat cell proliferation http://purl.obolibrary.org/obo/GO_0008283 cell population proliferation The multiplication or reproduction of fat cells by cell division, resulting in the expansion of their population. A fat cell is an animal connective tissue cell specialized for the synthesis and storage of fat. http://purl.obolibrary.org/obo/GO_0070342 brown fat cell proliferation http://purl.obolibrary.org/obo/GO_0070341 fat cell proliferation The multiplication or reproduction of brown fat cells by cell division, resulting in the expansion of their population. A brown fat cell is a fat cell found the thermogenic form of adipose tissue found in newborns of many species. http://purl.obolibrary.org/obo/GO_0070343 white fat cell proliferation http://purl.obolibrary.org/obo/GO_0070341 fat cell proliferation The multiplication or reproduction of white fat cells by cell division, resulting in the expansion of their population. http://purl.obolibrary.org/obo/GO_0070344 regulation of fat cell proliferation http://purl.obolibrary.org/obo/GO_0042127 regulation of cell population proliferation Any process that modulates the frequency, rate or extent of fat cell proliferation. http://purl.obolibrary.org/obo/GO_0070345 negative regulation of fat cell proliferation http://purl.obolibrary.org/obo/GO_0070344 regulation of fat cell proliferation Any process that stops or decreases the rate or extent of fat cell proliferation. http://purl.obolibrary.org/obo/GO_0070346 positive regulation of fat cell proliferation http://purl.obolibrary.org/obo/GO_0070344 regulation of fat cell proliferation Any process that activates or increases the rate or extent of fat cell proliferation. http://purl.obolibrary.org/obo/GO_0070347 regulation of brown fat cell proliferation http://purl.obolibrary.org/obo/GO_0070344 regulation of fat cell proliferation Any process that modulates the frequency, rate or extent of brown fat cell proliferation. http://purl.obolibrary.org/obo/GO_0070348 negative regulation of brown fat cell proliferation http://purl.obolibrary.org/obo/GO_0070347 regulation of brown fat cell proliferation Any process that stops or decreases the rate or extent of brown fat cell proliferation. http://purl.obolibrary.org/obo/GO_0070349 positive regulation of brown fat cell proliferation http://purl.obolibrary.org/obo/GO_0070347 regulation of brown fat cell proliferation Any process that activates or increases the rate or extent of brown fat cell proliferation. http://purl.obolibrary.org/obo/GO_0070350 regulation of white fat cell proliferation http://purl.obolibrary.org/obo/GO_0070344 regulation of fat cell proliferation Any process that modulates the frequency, rate or extent of white fat cell proliferation. http://purl.obolibrary.org/obo/GO_0070351 negative regulation of white fat cell proliferation http://purl.obolibrary.org/obo/GO_0070350 regulation of white fat cell proliferation Any process that stops or decreases the rate or extent of white fat cell proliferation. http://purl.obolibrary.org/obo/GO_0070352 positive regulation of white fat cell proliferation http://purl.obolibrary.org/obo/GO_0070350 regulation of white fat cell proliferation Any process that activates or increases the rate or extent of white fat cell proliferation. http://purl.obolibrary.org/obo/GO_0070365 hepatocyte differentiation http://purl.obolibrary.org/obo/GO_0030855 epithelial cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a hepatocyte. A hepatocyte is specialized epithelial cell that is organized into interconnected plates called lobules, and is the main structural component of the liver. http://purl.obolibrary.org/obo/GO_0070366 regulation of hepatocyte differentiation http://purl.obolibrary.org/obo/GO_0030856 regulation of epithelial cell differentiation Any process that modulates the frequency, rate or extent of hepatocyte differentiation. http://purl.obolibrary.org/obo/GO_0070367 negative regulation of hepatocyte differentiation http://purl.obolibrary.org/obo/GO_0070366 regulation of hepatocyte differentiation Any process that stops or decreases the rate or extent of hepatocyte differentiation. http://purl.obolibrary.org/obo/GO_0070368 positive regulation of hepatocyte differentiation http://purl.obolibrary.org/obo/GO_0070366 regulation of hepatocyte differentiation Any process that activates or increases the rate or extent of hepatocyte differentiation. http://purl.obolibrary.org/obo/GO_0070444 oligodendrocyte progenitor proliferation http://purl.obolibrary.org/obo/GO_0061351 neural precursor cell proliferation The multiplication or reproduction of oligodendrocyte progenitor cells by cell division, resulting in the expansion of their population. Oligodendrocyte progenitors give rise to oligodendrocytes, which form the insulating myelin sheath of axons in the central nervous system. http://purl.obolibrary.org/obo/GO_0070445 regulation of oligodendrocyte progenitor proliferation http://purl.obolibrary.org/obo/GO_2000177 regulation of neural precursor cell proliferation Any process that modulates the frequency, rate or extent of oligodendrocyte progenitor proliferation. http://purl.obolibrary.org/obo/GO_0070446 negative regulation of oligodendrocyte progenitor proliferation http://purl.obolibrary.org/obo/GO_0070445 regulation of oligodendrocyte progenitor proliferation Any process that stops or decreases the rate or extent of oligodendrocyte progenitor proliferation. http://purl.obolibrary.org/obo/GO_0070447 positive regulation of oligodendrocyte progenitor proliferation http://purl.obolibrary.org/obo/GO_0070445 regulation of oligodendrocyte progenitor proliferation Any process that activates or increases the rate or extent of oligodendrocyte progenitor proliferation. http://purl.obolibrary.org/obo/GO_0070451 cell hair http://purl.obolibrary.org/obo/GO_0120025 plasma membrane bounded cell projection A long, thin cell projection that contains F-actin and tubulin, with microtubules centrally located and F-actin peripherally located. http://purl.obolibrary.org/obo/GO_0070459 prolactin secretion http://purl.obolibrary.org/obo/GO_0030072 peptide hormone secretion The regulated release of prolactin, a peptide hormone that stimulates lactation, from secretory granules in the anterior pituitary. http://purl.obolibrary.org/obo/GO_0070460 thyroid-stimulating hormone secretion http://purl.obolibrary.org/obo/GO_0030072 peptide hormone secretion The regulated release of thyroid-stimulating hormone, a peptide hormone that stimulates the activity of the thyroid gland, from secretory granules in the anterior pituitary. http://purl.obolibrary.org/obo/GO_0070560 protein secretion by platelet http://purl.obolibrary.org/obo/GO_0140029 exocytic process The regulated release of proteins by a platelet or group of platelets. http://purl.obolibrary.org/obo/GO_0070634 transepithelial ammonium transport http://purl.obolibrary.org/obo/GO_0070633 transepithelial transport The directed movement of ammonium ions from one side of an epithelium to the other. http://purl.obolibrary.org/obo/GO_0070662 mast cell proliferation http://purl.obolibrary.org/obo/GO_0070661 leukocyte proliferation The expansion of a mast cell population by cell division. http://purl.obolibrary.org/obo/GO_0070666 regulation of mast cell proliferation http://purl.obolibrary.org/obo/GO_0070663 regulation of leukocyte proliferation Any process that modulates the frequency, rate or extent of mast cell proliferation. http://purl.obolibrary.org/obo/GO_0070667 negative regulation of mast cell proliferation http://purl.obolibrary.org/obo/GO_0070666 regulation of mast cell proliferation Any process that stops, prevents or reduces the rate or extent of mast cell proliferation. http://purl.obolibrary.org/obo/GO_0070668 positive regulation of mast cell proliferation http://purl.obolibrary.org/obo/GO_0070666 regulation of mast cell proliferation Any process that activates or increases the rate or extent of mast cell proliferation. http://purl.obolibrary.org/obo/GO_0070820 tertiary granule http://purl.obolibrary.org/obo/GO_0030141 secretory granule A secretory granule that contains cathepsin and gelatinase and is readily exocytosed upon cell activation; found primarily in mature neutrophil cells. http://purl.obolibrary.org/obo/GO_0070821 tertiary granule membrane http://purl.obolibrary.org/obo/GO_0030667 secretory granule membrane The lipid bilayer surrounding a tertiary granule. http://purl.obolibrary.org/obo/GO_0070830 bicellular tight junction assembly http://purl.obolibrary.org/obo/GO_0120192 tight junction assembly The aggregation, arrangement and bonding together of a set of components to form a tight junction, an occluding cell-cell junction that is composed of a branching network of sealing strands that completely encircles the apical end of each cell in an epithelial sheet. http://purl.obolibrary.org/obo/GO_0070831 basement membrane assembly http://purl.obolibrary.org/obo/GO_0085029 extracellular matrix assembly The aggregation, arrangement and bonding together of a set of components to form a basement membrane, a part of the extracellular region that consists of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue. http://purl.obolibrary.org/obo/GO_0070857 regulation of bile acid biosynthetic process http://purl.obolibrary.org/obo/GO_0050810 regulation of steroid biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids. http://purl.obolibrary.org/obo/GO_0070858 negative regulation of bile acid biosynthetic process http://purl.obolibrary.org/obo/GO_0070857 regulation of bile acid biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids. http://purl.obolibrary.org/obo/GO_0070859 positive regulation of bile acid biosynthetic process http://purl.obolibrary.org/obo/GO_0070857 regulation of bile acid biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids. http://purl.obolibrary.org/obo/GO_0070942 neutrophil mediated cytotoxicity http://purl.obolibrary.org/obo/GO_0002446 neutrophil mediated immunity The directed killing of a target cell by a neutrophil. http://purl.obolibrary.org/obo/GO_0070948 regulation of neutrophil mediated cytotoxicity http://purl.obolibrary.org/obo/GO_0002886 regulation of myeloid leukocyte mediated immunity Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a target cell, the directed killing of a target cell by a neutrophil. http://purl.obolibrary.org/obo/GO_0070954 negative regulation of neutrophil mediated cytotoxicity http://purl.obolibrary.org/obo/GO_0070948 regulation of neutrophil mediated cytotoxicity Any process that decreases the frequency, rate or extent of the directed killing of a target cell by a neutrophil. http://purl.obolibrary.org/obo/GO_0070960 positive regulation of neutrophil mediated cytotoxicity http://purl.obolibrary.org/obo/GO_0070948 regulation of neutrophil mediated cytotoxicity Any process that increases the frequency, rate or extent of the directed killing of a target cell by a neutrophil. http://purl.obolibrary.org/obo/GO_0070978 voltage-gated calcium channel complex assembly http://purl.obolibrary.org/obo/GO_0065003 protein-containing complex assembly Cellular protein complex assembly that results in the formation of a voltage-gated calcium channel complex. http://purl.obolibrary.org/obo/GO_0071166 ribonucleoprotein complex localization http://purl.obolibrary.org/obo/GO_0051641 cellular localization Any process in which a ribonucleoprotein complex is transported to, or maintained in, a specific location within a cell. http://purl.obolibrary.org/obo/GO_0071168 protein localization to chromatin http://purl.obolibrary.org/obo/GO_0034502 protein localization to chromosome Any process in which a protein is transported to, or maintained at, a part of a chromosome that is organized into chromatin. http://purl.obolibrary.org/obo/GO_0071169 establishment of protein localization to chromatin http://purl.obolibrary.org/obo/GO_0070199 establishment of protein localization to chromosome The directed movement of a protein to a part of a chromosome that is organized into chromatin. http://purl.obolibrary.org/obo/GO_0071214 cellular response to abiotic stimulus http://purl.obolibrary.org/obo/GO_0104004 cellular response to environmental stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (non-living) stimulus. http://purl.obolibrary.org/obo/GO_0071229 cellular response to acid chemical http://purl.obolibrary.org/obo/GO_0070887 cellular response to chemical stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by the chemical structure of the anion portion of the dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form. http://purl.obolibrary.org/obo/GO_0071277 cellular response to calcium ion http://purl.obolibrary.org/obo/GO_0071248 cellular response to metal ion Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus. http://purl.obolibrary.org/obo/GO_0071318 cellular response to ATP http://purl.obolibrary.org/obo/GO_1901701 cellular response to oxygen-containing compound Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ATP (adenosine 5'-triphosphate) stimulus. http://purl.obolibrary.org/obo/GO_0071326 cellular response to monosaccharide stimulus http://purl.obolibrary.org/obo/GO_0071322 cellular response to carbohydrate stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monosaccharide stimulus. http://purl.obolibrary.org/obo/GO_0071384 cellular response to corticosteroid stimulus http://purl.obolibrary.org/obo/GO_0071383 cellular response to steroid hormone stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosteroid hormone stimulus. A corticosteroid is a steroid hormone that is produced in the adrenal cortex. Corticosteroids are involved in a wide range of physiologic systems such as stress response, immune response and regulation of inflammation, carbohydrate metabolism, protein catabolism, blood electrolyte levels, and behavior. They include glucocorticoids and mineralocorticoids. http://purl.obolibrary.org/obo/GO_0071389 cellular response to mineralocorticoid stimulus http://purl.obolibrary.org/obo/GO_0071384 cellular response to corticosteroid stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mineralocorticoid stimulus. Mineralocorticoids are hormonal C21 corticosteroids synthesized from cholesterol and characterized by their similarity to aldosterone. Mineralocorticoids act primarily on water and electrolyte balance. http://purl.obolibrary.org/obo/GO_0071392 cellular response to estradiol stimulus http://purl.obolibrary.org/obo/GO_1901701 cellular response to oxygen-containing compound Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen. http://purl.obolibrary.org/obo/GO_0071393 cellular response to progesterone stimulus http://purl.obolibrary.org/obo/GO_1901655 cellular response to ketone Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a progesterone stimulus. http://purl.obolibrary.org/obo/GO_0071394 cellular response to testosterone stimulus http://purl.obolibrary.org/obo/GO_1901655 cellular response to ketone Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a testosterone stimulus. http://purl.obolibrary.org/obo/GO_0071398 cellular response to fatty acid http://purl.obolibrary.org/obo/GO_1901701 cellular response to oxygen-containing compound Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fatty acid stimulus. http://purl.obolibrary.org/obo/GO_0071402 cellular response to lipoprotein particle stimulus http://purl.obolibrary.org/obo/GO_0051716 cellular response to stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoprotein particle stimulus. http://purl.obolibrary.org/obo/GO_0071420 cellular response to histamine http://purl.obolibrary.org/obo/GO_1901699 cellular response to nitrogen compound Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histamine stimulus. Histamine, the biogenic amine 2-(1H-imidazol-4-yl)ethanamine, is involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter. http://purl.obolibrary.org/obo/GO_0071425 hematopoietic stem cell proliferation http://purl.obolibrary.org/obo/GO_0072089 stem cell proliferation The expansion of a hematopoietic stem cell population by cell division. A hematopoietic stem cell is a stem cell from which all cells of the lymphoid and myeloid lineages develop. http://purl.obolibrary.org/obo/GO_0071450 cellular response to oxygen radical http://purl.obolibrary.org/obo/GO_0034614 cellular response to reactive oxygen species Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen radical stimulus. An oxygen radical is any oxygen species that carries a free electron; examples include hydroxyl radicals and the superoxide anion. http://purl.obolibrary.org/obo/GO_0071542 dopaminergic neuron differentiation http://purl.obolibrary.org/obo/GO_0030182 neuron differentiation The process in which a neuroblast acquires the specialized structural and functional features of a dopaminergic neuron, a neuron that secretes dopamine. http://purl.obolibrary.org/obo/GO_0071599 otic vesicle development http://purl.obolibrary.org/obo/GO_0048839 inner ear development The process whose specific outcome is the progression of the otic vesicle over time, from its formation to the mature structure. The otic vesicle is a transient embryonic structure formed during development of the vertebrate inner ear. http://purl.obolibrary.org/obo/GO_0071623 negative regulation of granulocyte chemotaxis http://purl.obolibrary.org/obo/GO_0071622 regulation of granulocyte chemotaxis Any process that decreases the rate, frequency or extent of granulocyte chemotaxis. Granulocyte chemotaxis is the movement of a granulocyte in response to an external stimulus. http://purl.obolibrary.org/obo/GO_0071624 positive regulation of granulocyte chemotaxis http://purl.obolibrary.org/obo/GO_0071622 regulation of granulocyte chemotaxis Any process that increases the rate, frequency or extent of granulocyte chemotaxis. Granulocyte chemotaxis is the movement of a granulocyte in response to an external stimulus. http://purl.obolibrary.org/obo/GO_0071626 mastication http://purl.obolibrary.org/obo/GO_0022600 digestive system process The process of biting and mashing food with the teeth prior to swallowing. http://purl.obolibrary.org/obo/GO_0071670 smooth muscle cell chemotaxis http://purl.obolibrary.org/obo/GO_0014909 smooth muscle cell migration The directed movement of a smooth muscle cell in response to an external stimulus. http://purl.obolibrary.org/obo/GO_0071671 regulation of smooth muscle cell chemotaxis http://purl.obolibrary.org/obo/GO_0014910 regulation of smooth muscle cell migration Any process that modulates the frequency, rate, or extent of smooth muscle cell chemotaxis. http://purl.obolibrary.org/obo/GO_0071672 negative regulation of smooth muscle cell chemotaxis http://purl.obolibrary.org/obo/GO_0071671 regulation of smooth muscle cell chemotaxis Any process that stops, prevents, or reduces the frequency, rate, or extent of smooth muscle cell chemotaxis. http://purl.obolibrary.org/obo/GO_0071673 positive regulation of smooth muscle cell chemotaxis http://purl.obolibrary.org/obo/GO_0071671 regulation of smooth muscle cell chemotaxis Any process that activates or increases the frequency, rate, or extent of smooth muscle cell chemotaxis. http://purl.obolibrary.org/obo/GO_0071676 negative regulation of mononuclear cell migration http://purl.obolibrary.org/obo/GO_0071675 regulation of mononuclear cell migration Any process that decreases the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body. http://purl.obolibrary.org/obo/GO_0071677 positive regulation of mononuclear cell migration http://purl.obolibrary.org/obo/GO_0071675 regulation of mononuclear cell migration Any process that increases the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body. http://purl.obolibrary.org/obo/GO_0071696 ectodermal placode development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of an ectodermal placode over time from its initial formation until its mature state. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm. http://purl.obolibrary.org/obo/GO_0071697 ectodermal placode morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structures of an ectodermal placode are generated and organized. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm. http://purl.obolibrary.org/obo/GO_0071698 olfactory placode development http://purl.obolibrary.org/obo/GO_0071696 ectodermal placode development The progression of the olfactory placode over time from its initial formation until its mature state. The olfactory placode is a thickening of the neural ectoderm in the head region of the vertebrate embryo which develops into the olfactory region of the nasal cavity. http://purl.obolibrary.org/obo/GO_0071700 olfactory placode maturation http://purl.obolibrary.org/obo/GO_0071695 anatomical structure maturation A developmental process, independent of morphogenetic (shape) change, that is required for the olfactory placode to attain its fully functional state. The olfactory placode is a thickening of the neural ectoderm in the head region of the vertebrate embryo which develops into the olfactory region of the nasal cavity. http://purl.obolibrary.org/obo/GO_0071707 immunoglobulin heavy chain V-D-J recombination http://purl.obolibrary.org/obo/GO_0033152 immunoglobulin V(D)J recombination The process in which immunoglobulin heavy chain V, D, and J gene segments are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS). http://purl.obolibrary.org/obo/GO_0071708 immunoglobulin light chain V-J recombination http://purl.obolibrary.org/obo/GO_0033152 immunoglobulin V(D)J recombination The process in which immunoglobulin light chain V and J gene segments are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS). http://purl.obolibrary.org/obo/GO_0071732 cellular response to nitric oxide http://purl.obolibrary.org/obo/GO_1902170 cellular response to reactive nitrogen species Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitric oxide stimulus. http://purl.obolibrary.org/obo/GO_0071735 IgG immunoglobulin complex http://purl.obolibrary.org/obo/GO_0019814 immunoglobulin complex A protein complex composed of two identical immunoglobulin heavy chains of an IgG isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgG immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph. http://purl.obolibrary.org/obo/GO_0071736 IgG immunoglobulin complex, circulating http://purl.obolibrary.org/obo/GO_0071735 IgG immunoglobulin complex A protein complex composed of two identical immunoglobulin heavy chains of an IgG isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph. http://purl.obolibrary.org/obo/GO_0071738 IgD immunoglobulin complex http://purl.obolibrary.org/obo/GO_0019814 immunoglobulin complex A protein complex composed of two identical immunoglobulin heavy chains of the IgD isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgD immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph. http://purl.obolibrary.org/obo/GO_0071739 IgD immunoglobulin complex, circulating http://purl.obolibrary.org/obo/GO_0071738 IgD immunoglobulin complex A protein complex composed of two identical immunoglobulin heavy chains of the IgD isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph. http://purl.obolibrary.org/obo/GO_0071742 IgE immunoglobulin complex http://purl.obolibrary.org/obo/GO_0019814 immunoglobulin complex A protein complex composed of two identical immunoglobulin heavy chains of the IgE isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgE immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph. http://purl.obolibrary.org/obo/GO_0071743 IgE immunoglobulin complex, circulating http://purl.obolibrary.org/obo/GO_0071742 IgE immunoglobulin complex A protein complex composed of two identical immunoglobulin heavy chains of the IgE isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph. http://purl.obolibrary.org/obo/GO_0071745 IgA immunoglobulin complex http://purl.obolibrary.org/obo/GO_0019814 immunoglobulin complex A protein complex composed of two identical immunoglobulin heavy chains of the IgA isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and sometimes complexed with J chain or J chain and secretory component. An IgA immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph. http://purl.obolibrary.org/obo/GO_0071746 IgA immunoglobulin complex, circulating http://purl.obolibrary.org/obo/GO_0071745 IgA immunoglobulin complex A protein complex composed of two identical immunoglobulin heavy chains of an IgA isotype and two identical immunoglobulin light chains, held together by disulfide bonds, sometimes complexed with J chain or J chain and secretory component, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph. http://purl.obolibrary.org/obo/GO_0071753 IgM immunoglobulin complex http://purl.obolibrary.org/obo/GO_0019814 immunoglobulin complex A protein complex composed of two identical immunoglobulin heavy chains of the IgM isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and in its circulating form complexed with J chain in polymeric forms. An IgM immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph. http://purl.obolibrary.org/obo/GO_0071754 IgM immunoglobulin complex, circulating http://purl.obolibrary.org/obo/GO_0071753 IgM immunoglobulin complex A polymer of five or six IgM core units each composed of two identical immunoglobulin heavy chains of the IgM isotype and two identical immunoglobulin light chains, held together by disulfide bonds; the individual IgM core units are held together via disulfide bonds with a single J chain polypeptide acting as a bridge between two of the polymeric units. Circulating IgM is present in the extracellular space, in mucosal areas or other tissues, or in the blood or lymph. http://purl.obolibrary.org/obo/GO_0071764 nuclear outer membrane organization http://purl.obolibrary.org/obo/GO_0071763 nuclear membrane organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear outer membrane. http://purl.obolibrary.org/obo/GO_0071814 protein-lipid complex binding http://purl.obolibrary.org/obo/GO_0044877 protein-containing complex binding Binding to a protein-lipid complex, any macromolecular complex that contains both protein and lipid molecules. http://purl.obolibrary.org/obo/GO_0071868 cellular response to monoamine stimulus http://purl.obolibrary.org/obo/GO_1901699 cellular response to nitrogen compound Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monoamine stimulus. A monoamine is any of a group of molecular messengers that contain one amino group that is connected to an aromatic ring by ethylene group (-CH2-CH2-). Monoamines are derived from the aromatic amino acids phenylalanine, tyrosine, histidine and tryptophan. http://purl.obolibrary.org/obo/GO_0071869 response to catecholamine http://purl.obolibrary.org/obo/GO_0071867 response to monoamine Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catecholamine stimulus. A catecholamine is any of a group of biogenic amines that includes 4-(2-aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] and derivatives formed by substitution. http://purl.obolibrary.org/obo/GO_0071870 cellular response to catecholamine stimulus http://purl.obolibrary.org/obo/GO_0071869 response to catecholamine Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catecholamine stimulus. A catecholamine is any of a group of biogenic amines that includes 4-(2-aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] and derivatives formed by substitution. http://purl.obolibrary.org/obo/GO_0071873 response to norepinephrine http://purl.obolibrary.org/obo/GO_0071869 response to catecholamine Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a norepinephrine stimulus. Norepinephrine is a catecholamine that has the formula C8H11NO3; it acts as a hormone, and as a neurotransmitter in most of the sympathetic nervous system. http://purl.obolibrary.org/obo/GO_0071874 cellular response to norepinephrine stimulus http://purl.obolibrary.org/obo/GO_0071873 response to norepinephrine Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a norepinephrine stimulus. Norepinephrine is a catecholamine that has the formula C8H11NO3; it acts as a hormone, and as a neurotransmitter in most of the sympathetic nervous system. http://purl.obolibrary.org/obo/GO_0071888 macrophage apoptotic process http://purl.obolibrary.org/obo/GO_0071887 leukocyte apoptotic process Any apoptotic process in a macrophage, a mononuclear phagocyte present in a variety of tissues. http://purl.obolibrary.org/obo/GO_0071890 bicarbonate binding http://purl.obolibrary.org/obo/GO_0043168 anion binding Binding to bicarbonate ions (CHO3-). http://purl.obolibrary.org/obo/GO_0071895 odontoblast differentiation http://purl.obolibrary.org/obo/GO_0060563 neuroepithelial cell differentiation The process in which a relatively unspecialized cell of neural crest origin acquires the specialized features of an odontoblast, a cell on the outer surface of the dental pulp whose biological function is the creation of dentin. http://purl.obolibrary.org/obo/GO_0071953 elastic fiber http://purl.obolibrary.org/obo/GO_0099512 supramolecular fiber An supramolecular fiber that consists of an insoluble core of polymerized tropoelastin monomers and a surrounding mantle of microfibrils. Elastic fibers provide elasticity and recoiling to tissues and organs, and maintain structural integrity against mechanical strain. http://purl.obolibrary.org/obo/GO_0071971 extracellular exosome assembly http://purl.obolibrary.org/obo/GO_0070925 organelle assembly The aggregation, arrangement and bonding together of a set of components to form an extracellular vesicular exosome, a membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Exosomes are defined by their size, which generally ranges from 30 nm to 100 nm. http://purl.obolibrary.org/obo/GO_0072003 kidney rudiment formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The developmental process pertaining to the initial formation of a kidney rudiment from unspecified parts. A kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine. http://purl.obolibrary.org/obo/GO_0072007 mesangial cell differentiation http://purl.obolibrary.org/obo/GO_1904238 pericyte cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesangial cells of the kidney as it progresses from its formation to the mature state. http://purl.obolibrary.org/obo/GO_0072008 glomerular mesangial cell differentiation http://purl.obolibrary.org/obo/GO_0072007 mesangial cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the glomerular mesangial cells of the kidney as it progresses from its formation to the mature state. http://purl.obolibrary.org/obo/GO_0072009 nephron epithelium development http://purl.obolibrary.org/obo/GO_0072073 kidney epithelium development The process whose specific outcome is the progression of the nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The nephron epithelium is a tissue that covers the surface of a nephron. http://purl.obolibrary.org/obo/GO_0072010 glomerular epithelium development http://purl.obolibrary.org/obo/GO_0072009 nephron epithelium development The process whose specific outcome is the progression of the glomerular epithelium over time, from its formation to the mature structure. The glomerular epithelium is an epithelial tissue that covers the outer surfaces of the glomerulus. The glomerular epithelium consists of both parietal and visceral epithelium. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros. http://purl.obolibrary.org/obo/GO_0072011 glomerular endothelium development http://purl.obolibrary.org/obo/GO_0072010 glomerular epithelium development The process whose specific outcome is the progression of the glomerular endothelium over time, from its formation to the mature structure. The glomerular endothelium is an epithelial tissue that covers the internal surfaces of the glomerulus. http://purl.obolibrary.org/obo/GO_0072012 glomerulus vasculature development http://purl.obolibrary.org/obo/GO_0061440 kidney vasculature development The biological process whose specific outcome is the progression of a glomerulus vasculature from an initial condition to its mature state. This process begins with the formation of the glomerulus vasculature and ends with the mature structure. The glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the glomerulus. http://purl.obolibrary.org/obo/GO_0072015 podocyte development http://purl.obolibrary.org/obo/GO_0072310 glomerular epithelial cell development The process whose specific outcome is the progression of a glomerular visceral epithelial cell over time, from its formation to the mature structure. A glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells. http://purl.obolibrary.org/obo/GO_0072016 glomerular parietal epithelial cell development http://purl.obolibrary.org/obo/GO_0072310 glomerular epithelial cell development The process whose specific outcome is the progression of a glomerular parietal epithelial cell over time, from its formation to the mature structure. Glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. http://purl.obolibrary.org/obo/GO_0072019 proximal convoluted tubule development http://purl.obolibrary.org/obo/GO_0072080 nephron tubule development The process whose specific outcome is the progression of the proximal convoluted tubule over time, from its formation to the mature structure. The proximal convoluted tubule is the most proximal portion of the proximal tubule and extends from the glomerular capsule to the proximal straight tubule. http://purl.obolibrary.org/obo/GO_0072020 proximal straight tubule development http://purl.obolibrary.org/obo/GO_0072080 nephron tubule development The process whose specific outcome is the progression of the proximal straight tubule over time, from its formation to the mature structure. The proximal straight tubule is the part of the descending limb that extends from the proximal convoluted tubule to the descending thin tubule. http://purl.obolibrary.org/obo/GO_0072021 ascending thin limb development http://purl.obolibrary.org/obo/GO_0072080 nephron tubule development The process whose specific outcome is the progression of an ascending thin limb over time, from its formation to the mature structure. The ascending thin limb is a segment of a nephron tubule lying in the inner medulla that is permeable to ions but not to water and has a simple epithelium; active transepithelial solute transport is absent. http://purl.obolibrary.org/obo/GO_0072022 descending thin limb development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the descending thin limb over time, from its formation to the mature structure. The descending thin limb is a part of the loop of Henle situated just after the proximal straight tubule (S3). It extends to the tip of the loop of Henle. http://purl.obolibrary.org/obo/GO_0072023 thick ascending limb development http://purl.obolibrary.org/obo/GO_0072080 nephron tubule development The process whose specific outcome is the progression of the thick ascending limb over time, from its formation to the mature structure. The thick ascending limb is the last part of the loop of Henle. Its thick, mitochondria-rich epithelium characterizes the outer medulla, and is responsible for very avid active salt transport. At the macula densa, the thick ascending limb connects to the distal convoluted tubule. http://purl.obolibrary.org/obo/GO_0072024 macula densa development http://purl.obolibrary.org/obo/GO_0072009 nephron epithelium development The process whose specific outcome is the progression of the macula densa over time, from its formation to the mature structure. The macula densa is an area of specialized cells in the distal tubule that makes contact with the vascular pole of the glomerulus. http://purl.obolibrary.org/obo/GO_0072025 distal convoluted tubule development http://purl.obolibrary.org/obo/GO_0072080 nephron tubule development The process whose specific outcome is the progression of the distal convoluted tubule over time, from its formation to the mature structure. The distal convoluted tubule is the first segment of the nephron lying just downstream from the loop of Henle, immediately after the macula densa. Among other functions, in humans it is responsible for the reabsorption of about 5% of filtered sodium via the thiazide-sensitive Na-Cl symporter. http://purl.obolibrary.org/obo/GO_0072027 connecting tubule development http://purl.obolibrary.org/obo/GO_0072080 nephron tubule development The process whose specific outcome is the progression of the connecting tubule over time, from its formation to the mature structure. The connecting tubule is a tubular segment of the nephron; it connects the distal convoluted tubule to the collecting duct. http://purl.obolibrary.org/obo/GO_0072029 long nephron development http://purl.obolibrary.org/obo/GO_0072006 nephron development The process whose specific outcome is the progression of a long nephron over time, from its formation to the mature structure. Long nephrons are associated with juxtamedullary glomeruli and extend into the inner medulla. http://purl.obolibrary.org/obo/GO_0072030 short nephron development http://purl.obolibrary.org/obo/GO_0072006 nephron development The process whose specific outcome is the progression of a short nephron over time, from its formation to the mature structure. Short nephrons are associated with mid-cortical and superficial glomeruli, are situated entirely in the outer medulla, and have no thin ascending limb. http://purl.obolibrary.org/obo/GO_0072031 proximal convoluted tubule segment 1 development http://purl.obolibrary.org/obo/GO_0035295 tube development The process whose specific outcome is the progression of the S1 portion of the proximal convoluted tubule over time, from its formation to the mature structure. The S1 portion is the initial portion of the proximal convoluted tubule and is responsible for avid reabsorption of water and solutes. http://purl.obolibrary.org/obo/GO_0072032 proximal convoluted tubule segment 2 development http://purl.obolibrary.org/obo/GO_0035295 tube development The process whose specific outcome is the progression of the S2 portion of the proximal convoluted tubule over time, from its formation to the mature structure. The S2 portion of the tubule is involved in reabsorption of water and sodium chloride. http://purl.obolibrary.org/obo/GO_0072033 renal vesicle formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The developmental process pertaining to the initial formation of the renal vesicle from condensed mesenchymal cells. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells. http://purl.obolibrary.org/obo/GO_0072038 mesenchymal stem cell maintenance involved in nephron morphogenesis http://purl.obolibrary.org/obo/GO_0035019 somatic stem cell population maintenance The process in which an organism retains a population of mesenchymal stem cells that contributes to the shaping of a nephron. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells. http://purl.obolibrary.org/obo/GO_0072040 negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis http://purl.obolibrary.org/obo/GO_2001054 negative regulation of mesenchymal cell apoptotic process Any process that reduces the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron. http://purl.obolibrary.org/obo/GO_0072044 collecting duct development http://purl.obolibrary.org/obo/GO_0035295 tube development The process whose specific outcome is the progression of a collecting duct over time, from its formation to the mature structure. The collecting duct responds to vasopressin and aldosterone to regulate water, electrolyte and acid-base balance. It is the final common path through which urine flows before entering the ureter and then emptying into the bladder. http://purl.obolibrary.org/obo/GO_0072048 renal system pattern specification http://purl.obolibrary.org/obo/GO_0007389 pattern specification process Any developmental process that results in the creation of defined areas or spaces within an organism to which cells respond and eventually are instructed to differentiate into the anatomical structures of the renal system. http://purl.obolibrary.org/obo/GO_0072049 comma-shaped body morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the comma-shaped body is generated and organized. The comma-shaped body is the precursor structure to the S-shaped body that contributes to the morphogenesis of the nephron. http://purl.obolibrary.org/obo/GO_0072050 S-shaped body morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the S-shaped body is generated and organized. The S-shaped body is the successor of the comma-shaped body that contributes to the morphogenesis of the nephron. http://purl.obolibrary.org/obo/GO_0072051 juxtaglomerular apparatus development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the juxtaglomerular apparatus over time, from its formation to the mature structure. The juxtaglomerular apparatus is an anatomical structure that lies adjacent to the glomerulus and regulates kidney function. http://purl.obolibrary.org/obo/GO_0072052 juxtaglomerulus cell differentiation http://purl.obolibrary.org/obo/GO_0061005 cell differentiation involved in kidney development The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the juxtaglomerulus cells of the kidney as it progresses from its formation to the mature state. http://purl.obolibrary.org/obo/GO_0072053 renal inner medulla development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the renal inner medulla over time, from its formation to the mature structure. The renal inner medulla is unique to mammalian kidneys and is the innermost region of the mammalian kidney. http://purl.obolibrary.org/obo/GO_0072054 renal outer medulla development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the renal outer medulla over time, from its formation to the mature structure. The renal outer medulla is the region of the kidney that lies between the renal cortex and the renal inner medulla. http://purl.obolibrary.org/obo/GO_0072055 renal cortex development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the renal cortex over time, from its formation to the mature structure. The renal cortex is the outer region of the kidney. http://purl.obolibrary.org/obo/GO_0072056 pyramid development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the kidney pyramids over time, from its formation to the mature structure. Kidney pyramids are the conical masses that constitute the renal medulla in a multi-lobed mammalian kidney; they contain the loops of Henle and the medullary collecting ducts. http://purl.obolibrary.org/obo/GO_0072057 inner stripe development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the inner stripe over time, from its formation to the mature structure. The inner stripe is a deep, centrally located portion of the renal outer medulla and is traversed by thin descending and thick ascending portions of the loops of Henle. http://purl.obolibrary.org/obo/GO_0072058 outer stripe development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the outer stripe over time, from its formation to the mature structure. The outer stripe is the region of the kidney outer medulla that lies just below the cortex. The proximal straight tubules (S3) characterize this region. http://purl.obolibrary.org/obo/GO_0072059 cortical collecting duct development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the cortical collecting duct over time, from its formation to the mature structure. The cortical collecting duct is the portion of the collecting duct that resides in the renal cortex. http://purl.obolibrary.org/obo/GO_0072060 outer medullary collecting duct development http://purl.obolibrary.org/obo/GO_0072044 collecting duct development The process whose specific outcome is the progression of the outer medullary collecting duct over time, from its formation to the mature structure. The outer medullary collecting duct is the portion of the collecting duct that lies in the renal outer medulla. http://purl.obolibrary.org/obo/GO_0072061 inner medullary collecting duct development http://purl.obolibrary.org/obo/GO_0072044 collecting duct development The process whose specific outcome is the progression of the inner medullary collecting duct over time, from its formation to the mature structure. The inner medullary collecting duct is the portion of the collecting duct that lies in the renal inner medulla. http://purl.obolibrary.org/obo/GO_0072063 short descending thin limb development http://purl.obolibrary.org/obo/GO_0072022 descending thin limb development The process whose specific outcome is the progression of the short descending thin limb over time, from its formation to the mature structure. The short descending thin limb is the descending thin limb of a short nephron that has a squamous epithelial morphology. http://purl.obolibrary.org/obo/GO_0072064 long descending thin limb development http://purl.obolibrary.org/obo/GO_0072022 descending thin limb development The process whose specific outcome is the progression of the long descending thin limb over time, from its formation to the mature structure. The long descending thin limb is the descending thin limb of a long nephron that has a squamous epithelial morphology. The long descending limb starts in the inner stripe of the outer medulla and extends into the inner medulla. http://purl.obolibrary.org/obo/GO_0072067 early distal convoluted tubule development http://purl.obolibrary.org/obo/GO_0072009 nephron epithelium development The process whose specific outcome is the progression of the early distal convoluted tubule over time, from its formation to the mature structure. The early distal convoluted tubule contains DCT cells and is vasopressin-insensitive. http://purl.obolibrary.org/obo/GO_0072068 late distal convoluted tubule development http://purl.obolibrary.org/obo/GO_0072009 nephron epithelium development The process whose specific outcome is the progression of the late distal convoluted tubule over time, from its formation to the mature structure. The late distal convoluted tubule contains DCT cells and intercalated (IC) alpha and beta cells and is vasopressin-sensitive. http://purl.obolibrary.org/obo/GO_0072070 loop of Henle development http://purl.obolibrary.org/obo/GO_0072080 nephron tubule development The process whose specific outcome is the progression of the loop of Henle over time, from its formation to the mature structure. The loop of Henle is a nephron tubule that connects the proximal convoluted tubule to the distal convoluted tubule. http://purl.obolibrary.org/obo/GO_0072071 kidney interstitial fibroblast differentiation http://purl.obolibrary.org/obo/GO_0061005 cell differentiation involved in kidney development The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the interstitial fibroblast of the kidney as it progresses from its formation to the mature state. http://purl.obolibrary.org/obo/GO_0072073 kidney epithelium development http://purl.obolibrary.org/obo/GO_0060429 epithelium development The process whose specific outcome is the progression of an epithelium in the kidney over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. http://purl.obolibrary.org/obo/GO_0072074 kidney mesenchyme development http://purl.obolibrary.org/obo/GO_0060485 mesenchyme development The biological process whose specific outcome is the progression of a kidney mesenchyme from an initial condition to its mature state. This process begins with the formation of kidney mesenchyme and ends with the mature structure. Kidney mesenchyme is the tissue made up of loosely connected mesenchymal cells in the kidney. http://purl.obolibrary.org/obo/GO_0072075 metanephric mesenchyme development http://purl.obolibrary.org/obo/GO_0072074 kidney mesenchyme development The biological process whose specific outcome is the progression of a metanephric mesenchyme from an initial condition to its mature state. This process begins with the formation of metanephric mesenchyme and ends with the mature structure. Metanephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the metanephros. http://purl.obolibrary.org/obo/GO_0072076 nephrogenic mesenchyme development http://purl.obolibrary.org/obo/GO_0072074 kidney mesenchyme development The biological process whose specific outcome is the progression of a nephrogenic mesenchyme from an initial condition to its mature state. This process begins with the formation of nephrogenic mesenchyme and ends with the mature structure. Nephrogenic mesenchyme is the tissue made up of loosely connected mesenchymal cells in the nephron. http://purl.obolibrary.org/obo/GO_0072077 renal vesicle morphogenesis http://purl.obolibrary.org/obo/GO_0002009 morphogenesis of an epithelium The process in which the anatomical structures of the renal vesicle are generated and organized. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells. http://purl.obolibrary.org/obo/GO_0072087 renal vesicle development http://purl.obolibrary.org/obo/GO_0072073 kidney epithelium development The process whose specific outcome is the progression of the renal vesicle over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells. http://purl.obolibrary.org/obo/GO_0072088 nephron epithelium morphogenesis http://purl.obolibrary.org/obo/GO_0002009 morphogenesis of an epithelium The process in which the anatomical structures of the nephron epithelium are generated and organized. The nephron epithelium is a tissue that covers the surface of a nephron. http://purl.obolibrary.org/obo/GO_0072091 regulation of stem cell proliferation http://purl.obolibrary.org/obo/GO_0042127 regulation of cell population proliferation Any process that modulates the frequency, rate or extent of stem cell proliferation. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells. http://purl.obolibrary.org/obo/GO_0072093 metanephric renal vesicle formation http://purl.obolibrary.org/obo/GO_0072033 renal vesicle formation The developmental process pertaining to the initial formation of the metanephros. http://purl.obolibrary.org/obo/GO_0072099 anterior/posterior pattern specification involved in ureteric bud development http://purl.obolibrary.org/obo/GO_0009952 anterior/posterior pattern specification The developmental process that results in the creation of defined areas or spaces within the ureteric bud along the anterior/posterior axis to which cells respond and eventually are instructed to differentiate. http://purl.obolibrary.org/obo/GO_0072103 glomerulus vasculature morphogenesis http://purl.obolibrary.org/obo/GO_0061439 kidney vasculature morphogenesis The process in which the anatomical structures of the glomerulus vasculature are generated and organized. The glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the glomerulus. http://purl.obolibrary.org/obo/GO_0072104 glomerular capillary formation http://purl.obolibrary.org/obo/GO_0001525 angiogenesis The process that gives rise to a glomerular capillary. This process pertains to the initial formation of a structure from unspecified parts. http://purl.obolibrary.org/obo/GO_0072105 ureteric peristalsis http://purl.obolibrary.org/obo/GO_0014849 ureter smooth muscle contraction A wavelike sequence of involuntary muscular contraction and relaxation that passes along the ureter, impelling the contents onwards. The ureter is one of a pair of thick-walled tubes that transports urine from the kidney pelvis to the urinary bladder. http://purl.obolibrary.org/obo/GO_0072106 regulation of ureteric bud formation http://purl.obolibrary.org/obo/GO_1905276 regulation of epithelial tube formation Any process that modulates the developmental process pertaining to the initial formation of the ureteric bud from the Wolffian duct. http://purl.obolibrary.org/obo/GO_0072107 positive regulation of ureteric bud formation http://purl.obolibrary.org/obo/GO_1905278 positive regulation of epithelial tube formation Any process that increases the rate or extent of the developmental process pertaining to the initial formation of the ureteric bud from the Wolffian duct. http://purl.obolibrary.org/obo/GO_0072108 positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis http://purl.obolibrary.org/obo/GO_1905332 positive regulation of morphogenesis of an epithelium Any process that increases the rate, frequency or extent of the transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros. http://purl.obolibrary.org/obo/GO_0072109 glomerular mesangium development http://purl.obolibrary.org/obo/GO_0061448 connective tissue development The process whose specific outcome is the progression of the glomerular mesangium over time, from its formation to the mature structure. The glomerular mesangium is the thin membrane connective tissue composed of mesangial cells, which helps to support the capillary loops in a renal glomerulus. http://purl.obolibrary.org/obo/GO_0072112 podocyte differentiation http://purl.obolibrary.org/obo/GO_0072311 glomerular epithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a glomerular visceral epithelial cell. A glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells. http://purl.obolibrary.org/obo/GO_0072120 pronephros maturation http://purl.obolibrary.org/obo/GO_0048799 animal organ maturation A developmental process, independent of morphogenetic (shape) change, that is required for the pronephros to attain its fully functional state. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life. http://purl.obolibrary.org/obo/GO_0072127 renal capsule development http://purl.obolibrary.org/obo/GO_0061448 connective tissue development The process whose specific outcome is the progression of the renal capsule over time, from its formation to the mature structure. The renal capsule is the tough fibrous layer surrounding the kidney, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. During development, it comprises a single layer of flattened cells that lie just above the cortical stroma and the condensed mesenchyme of the nephrogenic zone. It is in this region that the early stages of nephron induction and formation of new generations ureteric bud branches occur, as the kidney expands. http://purl.obolibrary.org/obo/GO_0072128 renal capsule morphogenesis http://purl.obolibrary.org/obo/GO_0048729 tissue morphogenesis The process in which the anatomical structures of the renal capsule are generated and organized. The renal capsule is the tough fibrous layer surrounding the kidney, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. During development, it comprises a single layer of flattened cells that lie just above the cortical stroma and the condensed mesenchyme of the nephrogenic zone. It is in this region that the early stages of nephron induction and formation of new generations ureteric bud branches occur, as the kidney expands. http://purl.obolibrary.org/obo/GO_0072129 renal capsule formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The developmental process pertaining to the initial formation of a renal capsule from unspecified parts. The renal capsule is the tough fibrous layer surrounding the kidney, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. During development, it comprises a single layer of flattened cells that lie just above the cortical stroma and the condensed mesenchyme of the nephrogenic zone. It is in this region that the early stages of nephron induction and formation of new generations ureteric bud branches occur, as the kidney expands. http://purl.obolibrary.org/obo/GO_0072131 kidney mesenchyme morphogenesis http://purl.obolibrary.org/obo/GO_0072132 mesenchyme morphogenesis The process in which the anatomical structures of a kidney mesenchymal tissue are generated and organized. Kidney mesenchyme is the tissue made up of loosely connected mesenchymal cells in the kidney. http://purl.obolibrary.org/obo/GO_0072133 metanephric mesenchyme morphogenesis http://purl.obolibrary.org/obo/GO_0072131 kidney mesenchyme morphogenesis The process in which the anatomical structures of a metanephric mesenchymal tissue are generated and organized. Metanephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the metanephros. http://purl.obolibrary.org/obo/GO_0072134 nephrogenic mesenchyme morphogenesis http://purl.obolibrary.org/obo/GO_0072131 kidney mesenchyme morphogenesis The process in which the anatomical structures of a nephrogenic mesenchymal tissue are generated and organized. Nephrogenic mesenchyme is the tissue made up of loosely connected mesenchymal cells in the nephron. http://purl.obolibrary.org/obo/GO_0072138 mesenchymal cell proliferation involved in ureteric bud development http://purl.obolibrary.org/obo/GO_0072111 cell proliferation involved in kidney development The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population of the ureteric bud, that contributes to ureteric bud development. http://purl.obolibrary.org/obo/GO_0072139 glomerular parietal epithelial cell differentiation http://purl.obolibrary.org/obo/GO_0072311 glomerular epithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a glomerular parietal epithelial cell. Glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. http://purl.obolibrary.org/obo/GO_0072141 renal interstitial fibroblast development http://purl.obolibrary.org/obo/GO_0048468 cell development The process whose specific outcome is the progression of a renal interstitial fibroblast over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0072142 juxtaglomerulus cell development http://purl.obolibrary.org/obo/GO_0048468 cell development The process whose specific outcome is the progression of a juxtaglomerulus cell over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0072143 mesangial cell development http://purl.obolibrary.org/obo/GO_0048468 cell development The process whose specific outcome is the progression of a mesangial cell in the kidney over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0072144 glomerular mesangial cell development http://purl.obolibrary.org/obo/GO_0072143 mesangial cell development The process whose specific outcome is the progression of a glomerular mesangial cell in the kidney over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0072161 mesenchymal cell differentiation involved in kidney development http://purl.obolibrary.org/obo/GO_0061005 cell differentiation involved in kidney development The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the kidney as it progresses from its formation to the mature state. http://purl.obolibrary.org/obo/GO_0072163 mesonephric epithelium development http://purl.obolibrary.org/obo/GO_0072073 kidney epithelium development The process whose specific outcome is the progression of an epithelium in the mesonephros over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. http://purl.obolibrary.org/obo/GO_0072170 metanephric tubule development http://purl.obolibrary.org/obo/GO_0072207 metanephric epithelium development The progression of a metanephric tubule over time, from its initial formation to the mature structure. A metanephric tubule is an epithelial tube that is part of the metanephros. http://purl.obolibrary.org/obo/GO_0072171 mesonephric tubule morphogenesis http://purl.obolibrary.org/obo/GO_0072078 nephron tubule morphogenesis The process in which the anatomical structures of a mesonephric tubule are generated and organized. A mesonephric tubule is an epithelial tube that is part of the mesonephros. http://purl.obolibrary.org/obo/GO_0072172 mesonephric tubule formation http://purl.obolibrary.org/obo/GO_0072079 nephron tubule formation The developmental process pertaining to the initial formation of a mesonephric tubule from unspecified parts. A mesonephric tubule is an epithelial tube that is part of the mesonephros. http://purl.obolibrary.org/obo/GO_0072173 metanephric tubule morphogenesis http://purl.obolibrary.org/obo/GO_0060562 epithelial tube morphogenesis The process in which the anatomical structures of a metanephric tubule are generated and organized from an epithelium. A metanephric tubule is an epithelial tube that is part of the metanephros. http://purl.obolibrary.org/obo/GO_0072174 metanephric tubule formation http://purl.obolibrary.org/obo/GO_0072175 epithelial tube formation The developmental process pertaining to the initial formation of a metanephric tubule. http://purl.obolibrary.org/obo/GO_0072177 mesonephric duct development http://purl.obolibrary.org/obo/GO_0072176 nephric duct development The process whose specific outcome is the progression of a mesonephric duct over time, from its initial formation to a mature structure. A mesonephric duct is a tube drains the mesonephros. http://purl.obolibrary.org/obo/GO_0072179 nephric duct formation http://purl.obolibrary.org/obo/GO_0072175 epithelial tube formation The developmental process pertaining to the initial formation of a nephric duct. A nephric duct is a tube that drains a primitive kidney. http://purl.obolibrary.org/obo/GO_0072180 mesonephric duct morphogenesis http://purl.obolibrary.org/obo/GO_0072171 mesonephric tubule morphogenesis The process in which the anatomical structures of the mesonephric duct are generated and organized. A mesonephric duct is a tube drains the mesonephros. http://purl.obolibrary.org/obo/GO_0072181 mesonephric duct formation http://purl.obolibrary.org/obo/GO_0072180 mesonephric duct morphogenesis The developmental process pertaining to the initial formation of a mesonephric duct. A mesonephric duct is a tube that drains the mesonephros. http://purl.obolibrary.org/obo/GO_0072182 regulation of nephron tubule epithelial cell differentiation http://purl.obolibrary.org/obo/GO_2000696 regulation of epithelial cell differentiation involved in kidney development Any process that modulates the frequency, rate or extent of nephron tubule epithelial cell differentiation. http://purl.obolibrary.org/obo/GO_0072183 negative regulation of nephron tubule epithelial cell differentiation http://purl.obolibrary.org/obo/GO_0090185 negative regulation of kidney development Any process that decreases the frequency, rate or extent of nephron tubule epithelial cell differentiation. http://purl.obolibrary.org/obo/GO_0072190 ureter urothelium development http://purl.obolibrary.org/obo/GO_0060429 epithelium development The process whose specific outcome is the progression of the urothelium of the ureter over time, from its formation to the mature structure. The urothelium is an epithelium that makes up the epithelial tube of the ureter. http://purl.obolibrary.org/obo/GO_0072191 ureter smooth muscle development http://purl.obolibrary.org/obo/GO_0048745 smooth muscle tissue development The process whose specific outcome is the progression of smooth muscle in the ureter over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0072193 ureter smooth muscle cell differentiation http://purl.obolibrary.org/obo/GO_0051145 smooth muscle cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell in the ureter. http://purl.obolibrary.org/obo/GO_0072194 kidney smooth muscle tissue development http://purl.obolibrary.org/obo/GO_0048745 smooth muscle tissue development The process whose specific outcome is the progression of smooth muscle in the kidney over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0072198 mesenchymal cell proliferation involved in ureter development http://purl.obolibrary.org/obo/GO_0010463 mesenchymal cell proliferation The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population of the ureter, that contributes to ureter development. http://purl.obolibrary.org/obo/GO_0072200 negative regulation of mesenchymal cell proliferation involved in ureter development http://purl.obolibrary.org/obo/GO_0072201 negative regulation of mesenchymal cell proliferation Any process that decreases the frequency, rate or extent of mesenchymal cell proliferation that contributes to the progression of the ureter gland over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets. http://purl.obolibrary.org/obo/GO_0072201 negative regulation of mesenchymal cell proliferation http://purl.obolibrary.org/obo/GO_0008285 negative regulation of cell population proliferation Any process that decreases the frequency, rate or extent of mesenchymal cell proliferation. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets. http://purl.obolibrary.org/obo/GO_0072203 cell proliferation involved in metanephros development http://purl.obolibrary.org/obo/GO_0072111 cell proliferation involved in kidney development The multiplication or reproduction of cells, resulting in the expansion of the population in the metanephros. http://purl.obolibrary.org/obo/GO_0072205 metanephric collecting duct development http://purl.obolibrary.org/obo/GO_0072044 collecting duct development The process whose specific outcome is the progression of a collecting duct in the metanephros over time, from its formation to the mature structure. The collecting duct responds to vasopressin and aldosterone to regulate water, electrolyte and acid-base balance. The collecting duct is the final common path through which urine flows before entering the ureter and then emptying into the bladder. http://purl.obolibrary.org/obo/GO_0072206 metanephric juxtaglomerular apparatus development http://purl.obolibrary.org/obo/GO_0072051 juxtaglomerular apparatus development The process whose specific outcome is the progression of the juxtaglomerular apparatus in the metanephros over time, from its formation to the mature structure. The juxtaglomerular apparatus is an anatomical structure which consists of juxtaglomerular cells, extraglomerular mesangial cells and the macula densa. The juxtaglomerular apparatus lies adjacent to the glomerulus and regulates kidney function by maintaining the blood flow to the kidney and the filtration rate. http://purl.obolibrary.org/obo/GO_0072207 metanephric epithelium development http://purl.obolibrary.org/obo/GO_0072073 kidney epithelium development The process whose specific outcome is the progression of an epithelium in the metanephros over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. http://purl.obolibrary.org/obo/GO_0072208 metanephric smooth muscle tissue development http://purl.obolibrary.org/obo/GO_0072194 kidney smooth muscle tissue development The process whose specific outcome is the progression of smooth muscle in the metanephros over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0072210 metanephric nephron development http://purl.obolibrary.org/obo/GO_0072006 nephron development The process whose specific outcome is the progression of a nephron in the metanephros over time, from its formation to the mature structure. A nephron is the functional unit of the kidney. http://purl.obolibrary.org/obo/GO_0072211 metanephric pyramids development http://purl.obolibrary.org/obo/GO_0072056 pyramid development The process whose specific outcome is the progression of the metanephric pyramids over time, from their formation to the mature structures. Metanephric pyramids are the conical masses that constitute the renal medulla in a metanephros; they contain the loops of Henle and the medullary collecting ducts. http://purl.obolibrary.org/obo/GO_0072213 metanephric capsule development http://purl.obolibrary.org/obo/GO_0072127 renal capsule development The process whose specific outcome is the progression of the metanephric capsule over time, from its formation to the mature structure. The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. http://purl.obolibrary.org/obo/GO_0072214 metanephric cortex development http://purl.obolibrary.org/obo/GO_0072055 renal cortex development The process whose specific outcome is the progression of the metanephric cortex over time, from its formation to the mature structure. The metanephric cortex is the outer region of the metanephros. http://purl.obolibrary.org/obo/GO_0072216 positive regulation of metanephros development http://purl.obolibrary.org/obo/GO_0090184 positive regulation of kidney development Any process that increases the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine. http://purl.obolibrary.org/obo/GO_0072218 metanephric ascending thin limb development http://purl.obolibrary.org/obo/GO_0072234 metanephric nephron tubule development The process whose specific outcome is the progression of a metanephric ascending thin limb over time, from its formation to the mature structure. The metanephric ascending thin limb is a segment of a nephron tubule in the metanephros lying in the inner medulla that is permeable to ions but not to water and has a simple epithelium; active transepithelial solute transport is absent. http://purl.obolibrary.org/obo/GO_0072219 metanephric cortical collecting duct development http://purl.obolibrary.org/obo/GO_0072059 cortical collecting duct development The process whose specific outcome is the progression of the metanephric cortical collecting duct over time, from its formation to the mature structure. The metanephric cortical collecting duct is the portion of the metanephric collecting duct that resides in the renal cortex. http://purl.obolibrary.org/obo/GO_0072220 metanephric descending thin limb development http://purl.obolibrary.org/obo/GO_0072022 descending thin limb development The process whose specific outcome is the progression of the metanephric descending thin limb over time, from its formation to the mature structure. The metanephric descending thin limb is a part of the metanephric loop of Henle situated just after the proximal straight tubule (S3). It extends to the tip of the metanephric loop of Henle. http://purl.obolibrary.org/obo/GO_0072221 metanephric distal convoluted tubule development http://purl.obolibrary.org/obo/GO_0072234 metanephric nephron tubule development The process whose specific outcome is the progression of the metanephric distal convoluted tubule over time, from its formation to the mature structure. The metanephric distal convoluted tubule is the first segment of the metanephric nephron lying just downstream from the loop of Henle, immediately after the macula densa. Among other functions, in humans it is responsible for the reabsorption of about 5% of filtered sodium via the thiazide-sensitive Na-Cl symporter. http://purl.obolibrary.org/obo/GO_0072222 metanephric early distal convoluted tubule development http://purl.obolibrary.org/obo/GO_0072243 metanephric nephron epithelium development The process whose specific outcome is the progression of the metanephric early distal convoluted tubule over time, from its formation to the mature structure. The metanephric early distal convoluted tubule contains metanephric DCT cells and is vasopressin-insensitive. http://purl.obolibrary.org/obo/GO_0072223 metanephric glomerular mesangium development http://purl.obolibrary.org/obo/GO_0072109 glomerular mesangium development The process whose specific outcome is the progression of the metanephric glomerular mesangium over time, from its formation to the mature structure. The metanephric glomerular mesangium is the thin membrane connective tissue composed of mesangial cells in the metanephros, which helps to support the capillary loops in a renal glomerulus. http://purl.obolibrary.org/obo/GO_0072224 metanephric glomerulus development http://purl.obolibrary.org/obo/GO_0032835 glomerulus development The progression of the metanephric glomerulus over time from its initial formation until its mature state. The metanephric glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the mature vertebrate kidney, or metanephros. http://purl.obolibrary.org/obo/GO_0072225 metanephric late distal convoluted tubule development http://purl.obolibrary.org/obo/GO_0072243 metanephric nephron epithelium development The process whose specific outcome is the progression of the metanephric late distal convoluted tubule over time, from its formation to the mature structure. The metanephric late distal convoluted tubule contains metanephric DCT cells and intercalated (IC) alpha and beta cells and is vasopressin-sensitive. http://purl.obolibrary.org/obo/GO_0072227 metanephric macula densa development http://purl.obolibrary.org/obo/GO_0072243 metanephric nephron epithelium development The process whose specific outcome is the progression of the metanephric macula densa over time, from its formation to the mature structure. The metanephric macula densa is an area of specialized cells in the distal tubule of the metanephros that makes contact with the vascular pole of the glomerulus. http://purl.obolibrary.org/obo/GO_0072229 metanephric proximal convoluted tubule development http://purl.obolibrary.org/obo/GO_0072234 metanephric nephron tubule development The process whose specific outcome is the progression of the metanephric proximal convoluted tubule over time, from its formation to the mature structure. The metanephric proximal convoluted tubule is the most proximal portion of the metanephric proximal tubule and extends from the metanephric glomerular capsule to the metanephric proximal straight tubule. http://purl.obolibrary.org/obo/GO_0072230 metanephric proximal straight tubule development http://purl.obolibrary.org/obo/GO_0072234 metanephric nephron tubule development The process whose specific outcome is the progression of the metanephric proximal straight tubule over time, from its formation to the mature structure. The metanephric proximal straight tubule is the part of the metanephric descending limb that extends from the metanephric proximal convoluted tubule to the metanephric descending thin tubule. http://purl.obolibrary.org/obo/GO_0072231 metanephric proximal convoluted tubule segment 1 development http://purl.obolibrary.org/obo/GO_0072031 proximal convoluted tubule segment 1 development The process whose specific outcome is the progression of the S1 portion of the metanephric proximal convoluted tubule over time, from its formation to the mature structure. The S1 portion is the initial portion of the metanephric proximal convoluted tubule and is responsible for avid reabsorption of water and solutes. http://purl.obolibrary.org/obo/GO_0072233 metanephric thick ascending limb development http://purl.obolibrary.org/obo/GO_0072234 metanephric nephron tubule development The process whose specific outcome is the progression of the metanephric thick ascending limb over time, from its formation to the mature structure. The metanephric thick ascending limb is the last part of the metanephric loop of Henle. Its thick, mitochondria-rich epithelium characterizes the outer medulla, and is responsible for very avid active salt transport. At the macula densa, the thick ascending limb connects to the distal convoluted tubule. http://purl.obolibrary.org/obo/GO_0072234 metanephric nephron tubule development http://purl.obolibrary.org/obo/GO_0072243 metanephric nephron epithelium development The progression of a metanephric nephron tubule over time, from its initial formation to the mature structure. A metanephric nephron tubule is an epithelial tube that is part of the metanephric nephron, the functional part of the metanephros. http://purl.obolibrary.org/obo/GO_0072235 metanephric distal tubule development http://purl.obolibrary.org/obo/GO_0072234 metanephric nephron tubule development The process whose specific outcome is the progression of the metanephric distal tubule over time, from its formation to the mature structure. The metanephric distal tubule is a metanephric nephron tubule that begins at the metanephric macula densa and extends to the metanephric connecting tubule. http://purl.obolibrary.org/obo/GO_0072236 metanephric loop of Henle development http://purl.obolibrary.org/obo/GO_0072234 metanephric nephron tubule development The process whose specific outcome is the progression of the metanephric loop of Henle over time, from its formation to the mature structure. The metanephric loop of Henle is a metanephric nephron tubule that connects the proximal convoluted tubule to the distal convoluted tubule in the metanephros. http://purl.obolibrary.org/obo/GO_0072237 metanephric proximal tubule development http://purl.obolibrary.org/obo/GO_0072234 metanephric nephron tubule development The process whose specific outcome is the progression of the metanephric proximal tubule over time, from its formation to the mature structure. The metanephric proximal tubule is a metanephric nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle in the metanephros. It has a brush border epithelial morphology. http://purl.obolibrary.org/obo/GO_0072238 metanephric long nephron development http://purl.obolibrary.org/obo/GO_0072210 metanephric nephron development The process whose specific outcome is the progression of a metanephric long nephron over time, from its formation to the mature structure. Long nephrons are associated with juxtamedullary glomeruli and extend into the inner medulla in the metanephros. http://purl.obolibrary.org/obo/GO_0072239 metanephric glomerulus vasculature development http://purl.obolibrary.org/obo/GO_0072012 glomerulus vasculature development The biological process whose specific outcome is the progression of a metanephric glomerulus vasculature from an initial condition to its mature state. This process begins with the formation of the metanephric glomerulus vasculature and ends with the mature structure. The metanephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the metanephric glomerulus. http://purl.obolibrary.org/obo/GO_0072243 metanephric nephron epithelium development http://purl.obolibrary.org/obo/GO_0072207 metanephric epithelium development The process whose specific outcome is the progression of the metanephric nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The metanephric nephron epithelium is a tissue that covers the surface of a nephron in the metanephros. http://purl.obolibrary.org/obo/GO_0072244 metanephric glomerular epithelium development http://purl.obolibrary.org/obo/GO_0072243 metanephric nephron epithelium development The process whose specific outcome is the progression of the metanephric glomerular epithelium over time, from its formation to the mature structure. The metanephric glomerular epithelium is an epithelial tissue that covers the outer surfaces of the glomerulus in the metanephros. The metanephric glomerular epithelium consists of both parietal and visceral epithelium. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros. http://purl.obolibrary.org/obo/GO_0072248 metanephric podocyte differentiation http://purl.obolibrary.org/obo/GO_0072312 metanephric glomerular epithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a metanephric glomerular visceral epithelial cell. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros. http://purl.obolibrary.org/obo/GO_0072249 metanephric podocyte development http://purl.obolibrary.org/obo/GO_0072313 metanephric glomerular epithelial cell development The process whose specific outcome is the progression of a metanephric glomerular visceral epithelial cell over time, from its formation to the mature structure. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros. http://purl.obolibrary.org/obo/GO_0072257 metanephric nephron tubule epithelial cell differentiation http://purl.obolibrary.org/obo/GO_0072160 nephron tubule epithelial cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the metanephric nephron tubule as it progresses from its formation to the mature state. http://purl.obolibrary.org/obo/GO_0072264 metanephric glomerular endothelium development http://purl.obolibrary.org/obo/GO_0072244 metanephric glomerular epithelium development The process whose specific outcome is the progression of the metanephric glomerular endothelium over time, from its formation to the mature structure. The metanephric glomerular endothelium is an epithelial tissue that covers the internal surfaces of the glomerulus of the metanephros. http://purl.obolibrary.org/obo/GO_0072265 metanephric capsule morphogenesis http://purl.obolibrary.org/obo/GO_0072128 renal capsule morphogenesis The process in which the anatomical structures of the metanephric capsule are generated and organized. The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. http://purl.obolibrary.org/obo/GO_0072266 metanephric capsule formation http://purl.obolibrary.org/obo/GO_0072129 renal capsule formation The developmental process pertaining to the initial formation of a metanephric capsule from unspecified parts. The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. http://purl.obolibrary.org/obo/GO_0072268 pattern specification involved in metanephros development http://purl.obolibrary.org/obo/GO_0007389 pattern specification process Any developmental process that results in the creation of defined areas or spaces within the metanephros to which cells respond and eventually are instructed to differentiate. http://purl.obolibrary.org/obo/GO_0072269 metanephric long descending thin limb development http://purl.obolibrary.org/obo/GO_0072243 metanephric nephron epithelium development The process whose specific outcome is the progression of the metanephric long descending thin limb over time, from its formation to the mature structure. The metanephric long descending thin limb is the descending thin limb of a long nephron in the metanephros that has a squamous epithelial morphology. The long descending limb starts in the inner stripe of the outer medulla and extends into the inner medulla. http://purl.obolibrary.org/obo/GO_0072270 metanephric short nephron development http://purl.obolibrary.org/obo/GO_0072210 metanephric nephron development The process whose specific outcome is the progression of a short nephron in the metanephros over time, from its formation to the mature structure. Short nephrons are associated with mid-cortical and superficial glomeruli, are situated entirely in the outer medulla, and have no thin ascending limb. http://purl.obolibrary.org/obo/GO_0072271 metanephric short descending thin limb development http://purl.obolibrary.org/obo/GO_0072243 metanephric nephron epithelium development The process whose specific outcome is the progression of the metanephric short descending thin limb over time, from its formation to the mature structure. The metanephric short descending thin limb is the descending thin limb of a short nephron in the metanephros that has a squamous epithelial morphology. http://purl.obolibrary.org/obo/GO_0072273 metanephric nephron morphogenesis http://purl.obolibrary.org/obo/GO_0072028 nephron morphogenesis The process in which the anatomical structures of the metanephric nephron are generated and organized. A metanephric nephron is the functional unit of the metanephros. http://purl.obolibrary.org/obo/GO_0072275 metanephric glomerulus morphogenesis http://purl.obolibrary.org/obo/GO_0072102 glomerulus morphogenesis The process in which the anatomical structures of the metanephric glomerulus are generated and organized. The metanephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney, or metanephros. http://purl.obolibrary.org/obo/GO_0072276 metanephric glomerulus vasculature morphogenesis http://purl.obolibrary.org/obo/GO_0072103 glomerulus vasculature morphogenesis The process in which the anatomical structures of the metanephric glomerulus vasculature are generated and organized. The metanephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the metanephric glomerulus. http://purl.obolibrary.org/obo/GO_0072277 metanephric glomerular capillary formation http://purl.obolibrary.org/obo/GO_0072104 glomerular capillary formation The process that gives rise to a metanephric glomerular capillary. This process pertains to the initial formation of a structure from unspecified parts. http://purl.obolibrary.org/obo/GO_0072278 metanephric comma-shaped body morphogenesis http://purl.obolibrary.org/obo/GO_0072049 comma-shaped body morphogenesis The process in which the metanephric comma-shaped body is generated and organized. The metanephric comma-shaped body is the precursor structure to the metanephric S-shaped body that contributes to the morphogenesis of a nephron in the metanephros. http://purl.obolibrary.org/obo/GO_0072282 metanephric nephron tubule morphogenesis http://purl.obolibrary.org/obo/GO_0072173 metanephric tubule morphogenesis The process in which the anatomical structures of a metanephric nephron tubule are generated and organized. A metanephric nephron tubule is an epithelial tube that is part of the metanephric nephron, the functional part of the metanephros. http://purl.obolibrary.org/obo/GO_0072284 metanephric S-shaped body morphogenesis http://purl.obolibrary.org/obo/GO_0072050 S-shaped body morphogenesis The process in which the metanephric S-shaped body is generated and organized. The metanephric S-shaped body is the successor of the metanephric comma-shaped body that contributes to the morphogenesis of a nephron in the metanephros. http://purl.obolibrary.org/obo/GO_0072285 mesenchymal to epithelial transition involved in metanephric renal vesicle formation http://purl.obolibrary.org/obo/GO_0003337 mesenchymal to epithelial transition involved in metanephros morphogenesis A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephric renal vesicle. http://purl.obolibrary.org/obo/GO_0072286 metanephric connecting tubule development http://purl.obolibrary.org/obo/GO_0072234 metanephric nephron tubule development The process whose specific outcome is the progression of the metanephric connecting tubule over time, from its formation to the mature structure. The metanephric connecting tubule is a tubular segment of the metanephric nephron; it connects the distal convoluted tubule to the collecting duct in the metanephros. http://purl.obolibrary.org/obo/GO_0072287 metanephric distal tubule morphogenesis http://purl.obolibrary.org/obo/GO_0072282 metanephric nephron tubule morphogenesis The process in which the anatomical structures of a metanephric distal tubule are generated and organized. The metanephric distal tubule is a metanephric nephron tubule that begins at the macula densa and extends to the metanephric connecting tubule. http://purl.obolibrary.org/obo/GO_0072288 metanephric proximal tubule morphogenesis http://purl.obolibrary.org/obo/GO_0072282 metanephric nephron tubule morphogenesis The process in which the anatomical structures of a metanephric proximal tubule are generated and organized. The metanephric proximal tubule is a metanephric nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle in the metanephros. It has a brush border epithelial morphology. http://purl.obolibrary.org/obo/GO_0072289 metanephric nephron tubule formation http://purl.obolibrary.org/obo/GO_0072174 metanephric tubule formation The developmental process pertaining to the initial formation of a metanephric nephron tubule from unspecified parts. A metanephric nephron tubule is an epithelial tube that is part of a nephron in the metanephros. http://purl.obolibrary.org/obo/GO_0072298 regulation of metanephric glomerulus development http://purl.obolibrary.org/obo/GO_0090192 regulation of glomerulus development Any process that modulates the rate, frequency or extent of metanephric glomerulus development, the progression of the metanephric glomerulus over time from its initial formation until its mature state. The metanephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney, or metanephros. http://purl.obolibrary.org/obo/GO_0072299 negative regulation of metanephric glomerulus development http://purl.obolibrary.org/obo/GO_0090194 negative regulation of glomerulus development Any process that decreases the rate, frequency or extent of metanephric glomerulus development, the progression of the metanephric glomerulus over time from its initial formation until its mature state. The metanephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney, or metanephros. http://purl.obolibrary.org/obo/GO_0072300 positive regulation of metanephric glomerulus development http://purl.obolibrary.org/obo/GO_0090193 positive regulation of glomerulus development Any process that increases the rate, frequency or extent of metanephric glomerulus development, the progression of the metanephric glomerulus over time from its initial formation until its mature state. The metanephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney, or metanephros. http://purl.obolibrary.org/obo/GO_0072307 regulation of metanephric nephron tubule epithelial cell differentiation http://purl.obolibrary.org/obo/GO_0072182 regulation of nephron tubule epithelial cell differentiation Any process that modulates the frequency, rate or extent of metanephric nephron tubule epithelial cell differentiation. http://purl.obolibrary.org/obo/GO_0072308 negative regulation of metanephric nephron tubule epithelial cell differentiation http://purl.obolibrary.org/obo/GO_0072307 regulation of metanephric nephron tubule epithelial cell differentiation Any process that decreases the frequency, rate or extent of metanephric nephron tubule epithelial cell differentiation. http://purl.obolibrary.org/obo/GO_0072310 glomerular epithelial cell development http://purl.obolibrary.org/obo/GO_0002064 epithelial cell development The process whose specific outcome is the progression of a glomerular epithelial cell over time, from its formation to the mature structure. Glomerular epithelial cells are specialized epithelial cells that form part of the glomerulus; there are two types, glomerular parietal epithelial cells and glomerular visceral epithelial cells. http://purl.obolibrary.org/obo/GO_0072311 glomerular epithelial cell differentiation http://purl.obolibrary.org/obo/GO_0035850 epithelial cell differentiation involved in kidney development The process in which a relatively unspecialized cell acquires specialized features of a glomerular epithelial cell. Glomerular epithelial cells are specialized epithelial cells that form part of the glomerulus; there are two types, glomerular parietal epithelial cells and glomerular visceral epithelial cells. http://purl.obolibrary.org/obo/GO_0072312 metanephric glomerular epithelial cell differentiation http://purl.obolibrary.org/obo/GO_0072311 glomerular epithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a metanephric glomerular epithelial cell. Metanephric glomerular epithelial cells are specialized epithelial cells that form part of the metanephric glomerulus; there are two types, metanephric glomerular parietal epithelial cells and metanephric glomerular visceral epithelial cells. http://purl.obolibrary.org/obo/GO_0072313 metanephric glomerular epithelial cell development http://purl.obolibrary.org/obo/GO_0072310 glomerular epithelial cell development The process whose specific outcome is the progression of a metanephric glomerular epithelial cell over time, from its formation to the mature structure. Metanephric glomerular epithelial cells are specialized epithelial cells that form part of the metanephric glomerulus; there are two types, metanephric glomerular parietal epithelial cells and metanephric glomerular visceral epithelial cells. http://purl.obolibrary.org/obo/GO_0072343 pancreatic stellate cell proliferation http://purl.obolibrary.org/obo/GO_0048144 fibroblast proliferation The multiplication or reproduction of pancreatic stellate cells, resulting in the expansion of a pancreatic stellate cell population. Pancreatic stellate cells are found in the periacinar space of the exocrine pancreas and in perivascular and periductal regions of the pancreas, and have long cytoplasmic processes that encircle the base of the acinus. http://purl.obolibrary.org/obo/GO_0072360 vascular cord development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the vascular cord over time from its initial formation until its mature state. The vascular cord is the primordial vasculature that will develop into blood vessels by the process of tubulogenesis. http://purl.obolibrary.org/obo/GO_0072520 seminiferous tubule development http://purl.obolibrary.org/obo/GO_0048608 reproductive structure development The reproductive developmental process whose specific outcome is the progression of the seminiferous tubule over time, from its formation to the mature structure. Seminiferous tubules are ducts located in the testicles, and are the specific location of meiosis, and the subsequent creation of gametes, namely spermatozoa. http://purl.obolibrary.org/obo/GO_0072538 T-helper 17 type immune response http://purl.obolibrary.org/obo/GO_0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains An immune response which is associated with resistance to intracellular bacteria with a key role in inflammation and tissue injury. This immune response is associated with pathological autoimmune conditions such as multiple sclerosis, arthritis and psoriasis which is typically orchestrated by the production of particular cytokines by T-helper 17 cells, most notably interleukin-17, IL-21 and IL-22. http://purl.obolibrary.org/obo/GO_0072539 T-helper 17 cell differentiation http://purl.obolibrary.org/obo/GO_0042093 T-helper cell differentiation The process in which a relatively unspecialized T cell acquires the specialized features of a T-helper 17 (Th17) cell. A Th17 cell is a CD4-positive, alpha-beta T cell with the phenotype RORgamma-t-positive that produces IL-17. http://purl.obolibrary.org/obo/GO_0072553 terminal button organization http://purl.obolibrary.org/obo/GO_0099172 presynapse organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a terminal button. A terminal button is the terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters. http://purl.obolibrary.org/obo/GO_0072560 type B pancreatic cell maturation http://purl.obolibrary.org/obo/GO_0002070 epithelial cell maturation A developmental process, independent of morphogenetic (shape) change, that is required for a type B pancreatic cell to attain its fully functional state. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin. http://purl.obolibrary.org/obo/GO_0072574 hepatocyte proliferation http://purl.obolibrary.org/obo/GO_0050673 epithelial cell proliferation The multiplication or reproduction of hepatocytes, resulting in the expansion of a cell population. Hepatocytes form the main structural component of the liver. They are specialized epithelial cells that are organized into interconnected plates called lobules. http://purl.obolibrary.org/obo/GO_0072576 liver morphogenesis http://purl.obolibrary.org/obo/GO_0022612 gland morphogenesis The process in which the anatomical structures of the liver are generated and organized. http://purl.obolibrary.org/obo/GO_0072577 endothelial cell apoptotic process http://purl.obolibrary.org/obo/GO_0006915 apoptotic process Any apoptotic process in an endothelial cell. An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal. http://purl.obolibrary.org/obo/GO_0072592 oxygen metabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process The chemical reactions and pathways involving diatomic oxygen (O2). http://purl.obolibrary.org/obo/GO_0072597 maintenance of protein location in chloroplast http://purl.obolibrary.org/obo/GO_0072595 maintenance of protein localization in organelle Any process in which a protein is maintained in a specific location in a chloroplast, and is prevented from moving elsewhere. http://purl.obolibrary.org/obo/GO_0072598 protein localization to chloroplast http://purl.obolibrary.org/obo/GO_0033365 protein localization to organelle A process in which a protein is transported to, or maintained at, a location in a chloroplast. http://purl.obolibrary.org/obo/GO_0072656 maintenance of protein location in mitochondrion http://purl.obolibrary.org/obo/GO_0072595 maintenance of protein localization in organelle Any process in which a protein is maintained in a specific location in a mitochondrion, and is prevented from moving elsewhere. http://purl.obolibrary.org/obo/GO_0072665 protein localization to vacuole http://purl.obolibrary.org/obo/GO_0033365 protein localization to organelle A process in which a protein is transported to, or maintained at, a location in a vacuole. http://purl.obolibrary.org/obo/GO_0072667 maintenance of protein location in vacuole http://purl.obolibrary.org/obo/GO_0072595 maintenance of protein localization in organelle Any process in which a protein is maintained in a specific location in a vacuole, and is prevented from moving elsewhere. http://purl.obolibrary.org/obo/GO_0072674 multinuclear osteoclast differentiation http://purl.obolibrary.org/obo/GO_0030316 osteoclast differentiation The process in which a relatively unspecialized monocyte acquires the specialized features of a multinuclear osteoclast. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue. http://purl.obolibrary.org/obo/GO_0072679 thymocyte migration http://purl.obolibrary.org/obo/GO_0072678 T cell migration The movement of a thymocyte through distinct intrathymic niches (e.g. medulla, cortex), where it receives a unique set of developmental cues required for T-cell development. http://purl.obolibrary.org/obo/GO_0075296 positive regulation of ascospore formation http://purl.obolibrary.org/obo/GO_0090068 positive regulation of cell cycle process Any process that activates, maintains or increases the frequency, rate or extent of ascospore formation, a process in which a sexual spore, named ascospore, from Ascomycete fungi was produced inside an ascus. http://purl.obolibrary.org/obo/GO_0075297 negative regulation of ascospore formation http://purl.obolibrary.org/obo/GO_0010948 negative regulation of cell cycle process Any process that stops, prevents, or reduces the frequency, rate or extent of ascospore formation, a process in which a sexual spore, named ascospore, from Ascomycete fungi was produced inside an ascus. http://purl.obolibrary.org/obo/GO_0075298 regulation of zygospore formation http://purl.obolibrary.org/obo/GO_0043940 regulation of sexual sporulation resulting in formation of a cellular spore Any process that modulates the frequency, rate or extent of zygospore formation, a process in which a thick-walled spore of some algae and fungi is formed by union of two similar sexual cells, usually serves as a resting spore, and produces the sporophytic phase. http://purl.obolibrary.org/obo/GO_0075299 positive regulation of zygospore formation http://purl.obolibrary.org/obo/GO_0075298 regulation of zygospore formation Any process that activates, maintains or increases the frequency, rate or extent of frequency, rate or extent of zygospore formation, a process in which a thick-walled spore of some algae and fungi is formed by union of two similar sexual cells, usually serves as a resting spore, and produces the sporophytic phase. http://purl.obolibrary.org/obo/GO_0075300 negative regulation of zygospore formation http://purl.obolibrary.org/obo/GO_0075298 regulation of zygospore formation Any process that stops, prevents, or reduces the frequency, rate or extent of zygospore formation, a process in which a thick-walled spore of some algae and fungi is formed by union of two similar sexual cells, usually serves as a resting spore, and produces the sporophytic phase. http://purl.obolibrary.org/obo/GO_0075302 regulation of basidiospore formation http://purl.obolibrary.org/obo/GO_0043940 regulation of sexual sporulation resulting in formation of a cellular spore Any process that modulates the frequency, rate or extent of basidiospore formation, a process in which a sexually produced fungal spore is formed on a basidium in the fungi Basidiomycetes. http://purl.obolibrary.org/obo/GO_0075303 positive regulation of basidiospore formation http://purl.obolibrary.org/obo/GO_0075302 regulation of basidiospore formation Any process that activates, maintains or increases the frequency, rate or extent of frequency, rate or extent of basidiospore formation, a process in which a sexually produced fungal spore is formed on a basidium in the fungi basidiomycetes. http://purl.obolibrary.org/obo/GO_0075304 negative regulation of basidiospore formation http://purl.obolibrary.org/obo/GO_0075302 regulation of basidiospore formation Any process that stops, prevents, or reduces the frequency, rate or extent of basidiospore formation, a process in which a sexually produced fungal spore is formed on a basidium in the fungi basidiomycetes. http://purl.obolibrary.org/obo/GO_0080144 intracellular amino acid homeostasis http://purl.obolibrary.org/obo/GO_0055082 intracellular chemical homeostasis A homeostatic process involved in the maintenance of a steady state level of amino acids within a cell. http://purl.obolibrary.org/obo/GO_0086009 membrane repolarization http://purl.obolibrary.org/obo/GO_0042391 regulation of membrane potential The process in which ions are transported across a membrane such that the membrane potential changes in the repolarizing direction, toward the steady state potential. For example, the repolarization during an action potential is from a positive membrane potential towards a negative resting potential. http://purl.obolibrary.org/obo/GO_0090183 regulation of kidney development http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine. http://purl.obolibrary.org/obo/GO_0090184 positive regulation of kidney development http://purl.obolibrary.org/obo/GO_0090183 regulation of kidney development Any process that increases the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine. http://purl.obolibrary.org/obo/GO_0090185 negative regulation of kidney development http://purl.obolibrary.org/obo/GO_0090183 regulation of kidney development Any process that decreases the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine. http://purl.obolibrary.org/obo/GO_0090189 regulation of branching involved in ureteric bud morphogenesis http://purl.obolibrary.org/obo/GO_0090183 regulation of kidney development Any process that modulates the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules. http://purl.obolibrary.org/obo/GO_0090191 negative regulation of branching involved in ureteric bud morphogenesis http://purl.obolibrary.org/obo/GO_0090189 regulation of branching involved in ureteric bud morphogenesis Any process that decreases the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules. http://purl.obolibrary.org/obo/GO_0090192 regulation of glomerulus development http://purl.obolibrary.org/obo/GO_0090183 regulation of kidney development Any process that modulates the rate, frequency or extent of glomerulus development, the progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney. http://purl.obolibrary.org/obo/GO_0090193 positive regulation of glomerulus development http://purl.obolibrary.org/obo/GO_0090192 regulation of glomerulus development Any process that increases the rate, frequency or extent of glomerulus development, the progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney. http://purl.obolibrary.org/obo/GO_0090194 negative regulation of glomerulus development http://purl.obolibrary.org/obo/GO_0090192 regulation of glomerulus development Any process that decreases the rate, frequency or extent of glomerulus development, the progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney. http://purl.obolibrary.org/obo/GO_0090214 spongiotrophoblast layer developmental growth http://purl.obolibrary.org/obo/GO_0048589 developmental growth The increase in size or mass of the spongiotrophoblast layer of the placenta where the increase in size or mass contributes to the progression of that layer over time from its formation to its mature state. http://purl.obolibrary.org/obo/GO_0090425 acinar cell differentiation http://purl.obolibrary.org/obo/GO_0002067 glandular epithelial cell differentiation The epithelial cell differentiation process in which a relatively unspecialized cell acquires specialized features of an acinar cell, a secretory cell that is grouped together with other cells of the same type to form grape-shaped clusters known as acini. http://purl.obolibrary.org/obo/GO_0097084 vascular associated smooth muscle cell development http://purl.obolibrary.org/obo/GO_0055001 muscle cell development The process aimed at the progression of a vascular smooth muscle cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels. http://purl.obolibrary.org/obo/GO_0097094 craniofacial suture morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which any suture between cranial and/or facial bones is generated and organized. http://purl.obolibrary.org/obo/GO_0097186 amelogenesis http://purl.obolibrary.org/obo/GO_0042475 odontogenesis of dentin-containing tooth The process whose specific outcome is the formation of tooth enamel, occurring in two stages: secretory stage and maturation stage. http://purl.obolibrary.org/obo/GO_0097306 cellular response to alcohol http://purl.obolibrary.org/obo/GO_0097305 response to alcohol Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alcohol stimulus. http://purl.obolibrary.org/obo/GO_0097530 granulocyte migration http://purl.obolibrary.org/obo/GO_0097529 myeloid leukocyte migration The movement of a granulocyte within or between different tissues and organs of the body. http://purl.obolibrary.org/obo/GO_0097712 vesicle targeting, trans-Golgi to periciliary membrane compartment http://purl.obolibrary.org/obo/GO_0048199 vesicle targeting, to, from or within Golgi The process in which vesicles formed at the trans-Golgi network are directed to the plasma membrane surrounding the base of the cilium, including the ciliary pocket, mediated by molecules at the vesicle membrane and target membrane surfaces. http://purl.obolibrary.org/obo/GO_0097734 extracellular exosome biogenesis http://purl.obolibrary.org/obo/GO_0140112 extracellular vesicle biogenesis The assembly and secretion of an extracellular exosome, a membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. http://purl.obolibrary.org/obo/GO_0098771 inorganic ion homeostasis http://purl.obolibrary.org/obo/GO_0048878 chemical homeostasis Any process involved in the maintenance of an internal steady state of inorganic ions within an organism or cell. http://purl.obolibrary.org/obo/GO_0099124 axonal dopamine secretion http://purl.obolibrary.org/obo/GO_0014046 dopamine secretion The regulated release of dopamine from an axon. http://purl.obolibrary.org/obo/GO_0099565 chemical synaptic transmission, postsynaptic http://purl.obolibrary.org/obo/GO_0050877 nervous system process The part of synaptic transmission occurring in the post-synapse: a signal transduction pathway consisting of neurotransmitter receptor activation and its effects on postsynaptic membrane potential and the ionic composition of the postsynaptic cytosol. http://purl.obolibrary.org/obo/GO_0099623 regulation of cardiac muscle cell membrane repolarization http://purl.obolibrary.org/obo/GO_0060306 regulation of membrane repolarization Any process that modulates the establishment or extent of a change in membrane potential in the polarizing direction towards the resting potential in a cardiomyocyte. http://purl.obolibrary.org/obo/GO_0099624 atrial cardiac muscle cell membrane repolarization http://purl.obolibrary.org/obo/GO_0099622 cardiac muscle cell membrane repolarization The process in which ions are transported across the plasma membrane of an atrial cardiac muscle cell such that the membrane potential changes in the repolarizing direction, toward the steady state potential. For example, the repolarization during an action potential is from a positive membrane potential towards a negative resting potential. http://purl.obolibrary.org/obo/GO_0099625 ventricular cardiac muscle cell membrane repolarization http://purl.obolibrary.org/obo/GO_0099622 cardiac muscle cell membrane repolarization The process in which ions are transported across the plasma membrane of a ventricular cardiac muscle cell such that the membrane potential changes in the repolarizing direction, toward the steady state potential. For example, the repolarization during an action potential is from a positive membrane potential towards a negative resting potential. http://purl.obolibrary.org/obo/GO_1900120 regulation of receptor binding http://purl.obolibrary.org/obo/GO_0043393 regulation of protein binding Any process that modulates the frequency, rate or extent of a protein or other molecule binding to a receptor. http://purl.obolibrary.org/obo/GO_1900121 negative regulation of receptor binding http://purl.obolibrary.org/obo/GO_1900120 regulation of receptor binding Any process that stops, prevents or reduces the frequency, rate or extent of a protein or other molecule binding to a receptor. http://purl.obolibrary.org/obo/GO_1900212 negative regulation of mesenchymal cell apoptotic process involved in metanephros development http://purl.obolibrary.org/obo/GO_2001054 negative regulation of mesenchymal cell apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal cell apoptotic process involved in metanephros development. http://purl.obolibrary.org/obo/GO_1901145 mesenchymal cell apoptotic process involved in nephron morphogenesis http://purl.obolibrary.org/obo/GO_0097152 mesenchymal cell apoptotic process Any mesenchymal cell apoptotic process that is involved in nephron morphogenesis. http://purl.obolibrary.org/obo/GO_1901343 negative regulation of vasculature development http://purl.obolibrary.org/obo/GO_1901342 regulation of vasculature development Any process that stops, prevents or reduces the frequency, rate or extent of vasculature development. http://purl.obolibrary.org/obo/GO_1901653 cellular response to peptide http://purl.obolibrary.org/obo/GO_1901652 response to peptide Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide stimulus. http://purl.obolibrary.org/obo/GO_1901723 negative regulation of cell proliferation involved in kidney development http://purl.obolibrary.org/obo/GO_0008285 negative regulation of cell population proliferation Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation involved in kidney development. http://purl.obolibrary.org/obo/GO_1901724 positive regulation of cell proliferation involved in kidney development http://purl.obolibrary.org/obo/GO_0008284 positive regulation of cell population proliferation Any process that activates or increases the frequency, rate or extent of cell proliferation involved in kidney development. http://purl.obolibrary.org/obo/GO_1902019 regulation of cilium-dependent cell motility http://purl.obolibrary.org/obo/GO_2000145 regulation of cell motility Any process that modulates the frequency, rate or extent of cilium-dependent cell motility. http://purl.obolibrary.org/obo/GO_1902024 L-histidine transport http://purl.obolibrary.org/obo/GO_0015807 L-amino acid transport The directed movement of a L-histidine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_1902093 positive regulation of flagellated sperm motility http://purl.obolibrary.org/obo/GO_2000243 positive regulation of reproductive process Any process that activates or increases the frequency, rate or extent of flagellated sperm motility. http://purl.obolibrary.org/obo/GO_1902170 cellular response to reactive nitrogen species http://purl.obolibrary.org/obo/GO_1901699 cellular response to nitrogen compound Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive nitrogen species stimulus. http://purl.obolibrary.org/obo/GO_1902338 negative regulation of apoptotic process involved in morphogenesis http://purl.obolibrary.org/obo/GO_1904746 negative regulation of apoptotic process involved in development Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in morphogenesis. http://purl.obolibrary.org/obo/GO_1902339 positive regulation of apoptotic process involved in morphogenesis http://purl.obolibrary.org/obo/GO_1904747 positive regulation of apoptotic process involved in development Any process that activates or increases the frequency, rate or extent of apoptotic process involved in morphogenesis. http://purl.obolibrary.org/obo/GO_1902414 protein localization to cell junction http://purl.obolibrary.org/obo/GO_0008104 intracellular protein localization A process in which a protein is transported to, or maintained in, a location within a cell junction. http://purl.obolibrary.org/obo/GO_1902866 regulation of retina development in camera-type eye http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of retina development in camera-type eye. http://purl.obolibrary.org/obo/GO_1902867 negative regulation of retina development in camera-type eye http://purl.obolibrary.org/obo/GO_1902866 regulation of retina development in camera-type eye Any process that stops, prevents or reduces the frequency, rate or extent of retina development in camera-type eye. http://purl.obolibrary.org/obo/GO_1902868 positive regulation of retina development in camera-type eye http://purl.obolibrary.org/obo/GO_1902866 regulation of retina development in camera-type eye Any process that activates or increases the frequency, rate or extent of retina development in camera-type eye. http://purl.obolibrary.org/obo/GO_1903296 positive regulation of glutamate secretion, neurotransmission http://purl.obolibrary.org/obo/GO_0051968 positive regulation of synaptic transmission, glutamatergic Any process that activates or increases the frequency, rate or extent of glutamate secretion, where glutamate acts as a neurotransmitter. http://purl.obolibrary.org/obo/GO_1903317 regulation of protein maturation http://purl.obolibrary.org/obo/GO_0051246 regulation of protein metabolic process Any process that modulates the frequency, rate or extent of protein maturation. http://purl.obolibrary.org/obo/GO_1903489 positive regulation of lactation http://purl.obolibrary.org/obo/GO_1903487 regulation of lactation Any process that activates or increases the frequency, rate or extent of lactation. http://purl.obolibrary.org/obo/GO_1903561 extracellular vesicle http://purl.obolibrary.org/obo/GO_0031982 vesicle Any vesicle that is part of the extracellular region. http://purl.obolibrary.org/obo/GO_1903867 extraembryonic membrane development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of an extraembryonic membrane over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_1904019 epithelial cell apoptotic process http://purl.obolibrary.org/obo/GO_0006915 apoptotic process Any apoptotic process in an epithelial cell. http://purl.obolibrary.org/obo/GO_1904238 pericyte cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a pericyte cell. http://purl.obolibrary.org/obo/GO_1904672 regulation of somatic stem cell population maintenance http://purl.obolibrary.org/obo/GO_2000036 regulation of stem cell population maintenance Any process that modulates the frequency, rate or extent of somatic stem cell population maintenance. http://purl.obolibrary.org/obo/GO_1904673 negative regulation of somatic stem cell population maintenance http://purl.obolibrary.org/obo/GO_1904672 regulation of somatic stem cell population maintenance Any process that stops, prevents or reduces the frequency, rate or extent of somatic stem cell population maintenance. http://purl.obolibrary.org/obo/GO_1904674 positive regulation of somatic stem cell population maintenance http://purl.obolibrary.org/obo/GO_1904672 regulation of somatic stem cell population maintenance Any process that activates or increases the frequency, rate or extent of somatic stem cell population maintenance. http://purl.obolibrary.org/obo/GO_1905153 regulation of membrane invagination http://purl.obolibrary.org/obo/GO_0051128 regulation of cellular component organization Any process that modulates the frequency, rate or extent of membrane invagination. http://purl.obolibrary.org/obo/GO_1905154 negative regulation of membrane invagination http://purl.obolibrary.org/obo/GO_1905153 regulation of membrane invagination Any process that stops, prevents or reduces the frequency, rate or extent of membrane invagination. http://purl.obolibrary.org/obo/GO_1905155 positive regulation of membrane invagination http://purl.obolibrary.org/obo/GO_1905153 regulation of membrane invagination Any process that activates or increases the frequency, rate or extent of membrane invagination. http://purl.obolibrary.org/obo/GO_1905276 regulation of epithelial tube formation http://purl.obolibrary.org/obo/GO_2000026 regulation of multicellular organismal development Any process that modulates the frequency, rate or extent of epithelial tube formation. http://purl.obolibrary.org/obo/GO_1905278 positive regulation of epithelial tube formation http://purl.obolibrary.org/obo/GO_1905276 regulation of epithelial tube formation Any process that activates or increases the frequency, rate or extent of epithelial tube formation. http://purl.obolibrary.org/obo/GO_1905292 regulation of neural crest cell differentiation http://purl.obolibrary.org/obo/GO_2000736 regulation of stem cell differentiation Any process that modulates the frequency, rate or extent of neural crest cell differentiation. http://purl.obolibrary.org/obo/GO_1905293 negative regulation of neural crest cell differentiation http://purl.obolibrary.org/obo/GO_1905292 regulation of neural crest cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of neural crest cell differentiation. http://purl.obolibrary.org/obo/GO_1905294 positive regulation of neural crest cell differentiation http://purl.obolibrary.org/obo/GO_1905292 regulation of neural crest cell differentiation Any process that activates or increases the frequency, rate or extent of neural crest cell differentiation. http://purl.obolibrary.org/obo/GO_1905349 ciliary transition zone assembly http://purl.obolibrary.org/obo/GO_0022607 cellular component assembly The aggregation, arrangement and bonding together of a set of components to form a ciliary transition zone. http://purl.obolibrary.org/obo/GO_1905508 protein localization to microtubule organizing center http://purl.obolibrary.org/obo/GO_0072698 protein localization to microtubule cytoskeleton A process in which a protein is transported to, or maintained in, a location within a microtubule organizing center. http://purl.obolibrary.org/obo/GO_1905516 positive regulation of fertilization http://purl.obolibrary.org/obo/GO_2000243 positive regulation of reproductive process Any process that activates or increases the frequency, rate or extent of fertilization. http://purl.obolibrary.org/obo/GO_1905634 regulation of protein localization to chromatin http://purl.obolibrary.org/obo/GO_0032880 regulation of protein localization Any process that modulates the frequency, rate or extent of protein localization to chromatin. http://purl.obolibrary.org/obo/GO_1905809 negative regulation of synapse organization http://purl.obolibrary.org/obo/GO_0051129 negative regulation of cellular component organization Any process that stops, prevents or reduces the frequency, rate or extent of synapse organization. http://purl.obolibrary.org/obo/GO_1990504 dense core granule exocytosis http://purl.obolibrary.org/obo/GO_0017156 calcium-ion regulated exocytosis The secretion of molecules (e.g. neuropeptides, insulin-related peptides or neuromodulators such as serotonin and dopamine) contained within a membrane-bounced dense core granule by fusion of the granule with the plasma membrane of a cell in response to increased cytosolic calcium levels. http://purl.obolibrary.org/obo/GO_1990748 cellular detoxification http://purl.obolibrary.org/obo/GO_0098754 detoxification Any process carried out at the cellular level that reduces or removes the toxicity of a toxic substance. These may include transport of the toxic substance away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance. http://purl.obolibrary.org/obo/GO_2000070 regulation of response to water deprivation http://purl.obolibrary.org/obo/GO_0080134 regulation of response to stress Any process that modulates the frequency, rate or extent of response to water deprivation. http://purl.obolibrary.org/obo/GO_2000183 negative regulation of progesterone biosynthetic process http://purl.obolibrary.org/obo/GO_0010894 negative regulation of steroid biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of progesterone biosynthetic process. http://purl.obolibrary.org/obo/GO_2000543 positive regulation of gastrulation http://purl.obolibrary.org/obo/GO_0010470 regulation of gastrulation Any process that activates or increases the frequency, rate or extent of gastrulation. http://purl.obolibrary.org/obo/GO_2000725 regulation of cardiac muscle cell differentiation http://purl.obolibrary.org/obo/GO_0051153 regulation of striated muscle cell differentiation Any process that modulates the frequency, rate or extent of cardiac muscle cell differentiation. http://purl.obolibrary.org/obo/GO_2000726 negative regulation of cardiac muscle cell differentiation http://purl.obolibrary.org/obo/GO_2000725 regulation of cardiac muscle cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle cell differentiation. http://purl.obolibrary.org/obo/GO_2000727 positive regulation of cardiac muscle cell differentiation http://purl.obolibrary.org/obo/GO_2000725 regulation of cardiac muscle cell differentiation Any process that activates or increases the frequency, rate or extent of cardiac muscle cell differentiation. http://purl.obolibrary.org/obo/GO_2000794 regulation of epithelial cell proliferation involved in lung morphogenesis http://purl.obolibrary.org/obo/GO_0050678 regulation of epithelial cell proliferation Any process that modulates the frequency, rate or extent of epithelial cell proliferation involved in lung morphogenesis. http://purl.obolibrary.org/obo/GO_2001013 epithelial cell proliferation involved in renal tubule morphogenesis http://purl.obolibrary.org/obo/GO_0050673 epithelial cell proliferation Any epithelial cell proliferation that is involved in renal tubule morphogenesis. http://purl.obolibrary.org/obo/GO_2001053 regulation of mesenchymal cell apoptotic process http://purl.obolibrary.org/obo/GO_0042981 regulation of apoptotic process Any process that modulates the frequency, rate or extent of mesenchymal cell apoptotic process. http://purl.obolibrary.org/obo/GO_2001054 negative regulation of mesenchymal cell apoptotic process http://purl.obolibrary.org/obo/GO_2001053 regulation of mesenchymal cell apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal cell apoptotic process. http://purl.obolibrary.org/obo/GO_2001055 positive regulation of mesenchymal cell apoptotic process http://purl.obolibrary.org/obo/GO_2001053 regulation of mesenchymal cell apoptotic process Any process that activates or increases the frequency, rate or extent of mesenchymal cell apoptotic process. http://purl.obolibrary.org/obo/PR_000008982 interleukin-17 receptor B http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human IL17RB gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000008994 interleukin-1 receptor-like 1 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human IL1RL1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000009054 preproinsulin http://purl.obolibrary.org/obo/PR_000045358 insulin family protein An insulin family protein that is a translation product of the human INS gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000009127 integrin alpha-IIb http://purl.obolibrary.org/obo/PR_000025797 integrin alpha lacking A domain An integrin alpha lacking A domain that is a translation product of the human ITGA2B gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000009129 integrin alpha-4 http://purl.obolibrary.org/obo/PR_000025797 integrin alpha lacking A domain An integrin alpha lacking A domain that is a translation product of the human ITGA4 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000009143 integrin beta-7 http://purl.obolibrary.org/obo/PR_000001861 integrin beta An integrin beta that is a translation product of the human ITGB7 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000009344 metastasis-suppressor KiSS-1 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human KISS1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000009426 killer cell lectin-like receptor subfamily G member 1 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human KLRG1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000009616 T-cell surface glycoprotein YE1/48 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the mouse Klra1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000009618 killer cell lectin-like receptor 3 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the mouse Klra3 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000009619 killer cell lectin-like receptor 4 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the mouse Klra4 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000009623 killer cell lectin-like receptor 8 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the mouse Klra8 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000009725 neutrophil gelatinase-associated lipocalin http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human LCN2 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000009766 galectin-1 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human LGALS1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000009793 LIM/homeobox protein Lhx3 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human LHX3 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000009978 lactotransferrin http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human LTF gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000009981 lumican http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human LUM gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000010317 homeobox protein Meis2 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human MEIS2 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000010329 tyrosine-protein kinase Mer http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human MERTK gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000010529 DBH-like monooxygenase protein 1 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human MOXD1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000010799 myb proto-oncogene protein http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human MYB gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000011118 neurofilament heavy polypeptide http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human NEFH gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000011143 neuropilin and tolloid-like protein 1 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human NETO1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000011178 nuclear factor NF-kappa-B p100 subunit http://purl.obolibrary.org/obo/PR_000001753 transcription factor NF-kappa-B subunit A transcription factor NF-kappa-B subunit that is a translation product of the human NFKB2 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000011241 homeobox protein Nkx-2.1 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human NKX2-1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000011326 nitric oxide synthase 1 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human NOS1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000011387 neuropeptide Y http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human NPY gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000011467 netrin-G1 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human NTNG1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000012190 P2X purinoceptor 3 http://purl.obolibrary.org/obo/PR_000044669 P2X receptor protein A P2X receptor protein that is a translation product of the human P2RX3 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000012318 paired box protein Pax-6 http://purl.obolibrary.org/obo/PR_000037798 paired box protein PAX group IV A paired box protein PAX group IV that is a translation product of the human PAX6 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000012526 proenkephalin-B http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human PDYN gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000012544 proenkephalin-A http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human PENK gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000013015 pro-opiomelanocortin http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human POMC gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000013031 periostin http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human POSTN gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000013041 POU domain, class 4, transcription factor 1 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human POU4F1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000013047 POU domain, class 6, transcription factor 2 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human POU6F2 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000013206 bone marrow proteoglycan http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human PRG2 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000013208 proteoglycan 4 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human PRG4 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000013246 prolactin http://purl.obolibrary.org/obo/PR_000029968 somatotropin hormone family member A somatotropin hormone family member that is a translation product of the human PRL gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000013289 peripherin http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human PRPH gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000013433 parathyroid hormone-related protein http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human PTHLH gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000013502 parvalbumin alpha http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human PVALB gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000013879 reelin http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human RELN gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000013883 renin http://purl.obolibrary.org/obo/PR_000050025 angiotensinogenase An angiotensinogenase that is a translation product of the human REN gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000013895 proto-oncogene tyrosine-protein kinase receptor Ret http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human RET gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000014046 non-secretory ribonuclease http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human RNASE2 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000014047 eosinophil cationic protein http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human RNASE3 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000014362 runt-related transcription factor 1 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human RUNX1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000014419 protein S100-B http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human S100B gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000014505 uteroglobin http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human SCGB1A1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000025797 integrin alpha lacking A domain http://purl.obolibrary.org/obo/PR_000025796 integrin alpha An integrin alpha that lacks an A domain. This type of integrin is often cleaved into heavy and light chains. http://purl.obolibrary.org/obo/PR_000027795 trypsin http://purl.obolibrary.org/obo/PR_000000001 protein A protein that in active form is a serine protease that cleaves peptide bonds on the carboxyl side of lysine or arginine amino acids within amino acid chains. http://purl.obolibrary.org/obo/PR_000037798 paired box protein PAX group IV http://purl.obolibrary.org/obo/PR_000037797 paired box protein PAX A paired box protein PAX that contains, in addition to the 'Paired box' domain (Pfam:PF00292), a C-terminal Homeobox domain (Pfam:PF00046). http://purl.obolibrary.org/obo/PR_000045358 insulin family protein http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of a gene that encodes a standalone Insulin (Pfam:PF00049) domain preceded by a signal peptide. http://purl.obolibrary.org/obo/PR_000037797 paired box protein PAX http://purl.obolibrary.org/obo/PR_000000001 protein A protein that contains a copy of the 'Paired box' domain (Pfam:PF00292), a conserved amino acid motif with DNA-binding activity. Members of this class are transcription factors involved in pattern formation during embryogenesis, possibly by determining the time and place of organ initiation or morphogenesis. http://purl.obolibrary.org/obo/PR_Q62226 sonic hedgehog protein (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A sonic hedgehog protein that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q9P2W7 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_O35205 granzyme K (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A granzyme K that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_O35304 vesicular acetylcholine transporter (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A vesicular acetylcholine transporter that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_O35305 tumor necrosis factor receptor superfamily member 11A (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A tumor necrosis factor receptor superfamily member 11A that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_O35417 proenkephalin-B (mouse) http://purl.obolibrary.org/obo/PR_000012526 proenkephalin-B A proenkephalin-B that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_O35930 platelet glycoprotein Ib alpha chain (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A platelet glycoprotein Ib alpha chain that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_O43490 prominin-1 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A prominin-1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_O54689 C-C chemokine receptor type 6 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A C-C chemokine receptor type 6 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_O54707 natural killer cells antigen CD94 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A killer cell lectin-like receptor subfamily D member 1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_O54839 eomesodermin homolog (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein An eomesodermin that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_O54990 prominin-1 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A prominin-1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P0CW03 lymphocyte antigen 6C2 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A lymphocyte antigen 6C2 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P0DN78 medium-wave-sensitive opsin 3 (human) http://purl.obolibrary.org/obo/PR_000050522 medium-wave-sensitive opsin (human) A medium-wave-sensitive opsin (human) that is a translation product of the OPN1MW3 gene in human. http://purl.obolibrary.org/obo/PR_P10144 granzyme B (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A granzyme B that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P10153 non-secretory ribonuclease (human) http://purl.obolibrary.org/obo/PR_000014046 non-secretory ribonuclease A non-secretory ribonuclease that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P10300 T-cell surface glycoprotein CD8 beta chain (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A T-cell surface glycoprotein CD8 beta chain that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P10810 monocyte differentiation antigen CD14 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A CD14 molecule that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P10820 perforin-1 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A perforin-1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P10855 C-C motif chemokine 3 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A C-C motif chemokine 3 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P10966-1 T-cell surface glycoprotein CD8 beta chain isoform 1 (human) http://purl.obolibrary.org/obo/PR_P10966 T-cell surface glycoprotein CD8 beta chain (human) A T-cell surface glycoprotein CD8 beta chain isoform 1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P11087 collagen alpha-1(I) chain (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A collagen alpha-1(I) chain that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P11161 E3 SUMO-protein ligase EGR2 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein An early growth response protein 2 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P11247 myeloperoxidase (mouse) http://purl.obolibrary.org/obo/PR_000010543 myeloperoxidase A myeloperoxidase that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P11609 antigen-presenting glycoprotein CD1d1 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein An antigen-presenting glycoprotein CD1d that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P11672 neutrophil gelatinase-associated lipocalin (mouse) http://purl.obolibrary.org/obo/PR_000009725 neutrophil gelatinase-associated lipocalin A neutrophil gelatinase-associated lipocalin that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P11678 eosinophil peroxidase (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein An eosinophil peroxidase that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P11684 uteroglobin (human) http://purl.obolibrary.org/obo/PR_000014505 uteroglobin A uteroglobin that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P11836 B-lymphocyte antigen CD20 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A membrane-spanning 4-domains subfamily A member 1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P12018 immunoglobulin iota chain (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein An immunoglobulin iota chain that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P12036 neurofilament heavy polypeptide (human) http://purl.obolibrary.org/obo/PR_000011118 neurofilament heavy polypeptide A neurofilament heavy polypeptide that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P12272 parathyroid hormone-related protein (human) http://purl.obolibrary.org/obo/PR_000013433 parathyroid hormone-related protein A parathyroid hormone-related protein that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P12724 eosinophil cationic protein (human) http://purl.obolibrary.org/obo/PR_000014047 eosinophil cationic protein An eosinophil cationic protein that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P12830 cadherin-1 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A cadherin-1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P13379 T-cell surface glycoprotein CD5 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A T-cell surface glycoprotein CD5 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P13595 neural cell adhesion molecule 1 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A neural cell adhesion molecule 1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P13727 bone marrow proteoglycan (human) http://purl.obolibrary.org/obo/PR_000013206 bone marrow proteoglycan A bone marrow proteoglycan that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P13727-1 bone marrow proteoglycan isoform 1 (human) http://purl.obolibrary.org/obo/PR_P13727 bone marrow proteoglycan (human) A bone marrow proteoglycan isoform 1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P14136 glial fibrillary acidic protein (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A glial fibrillary acidic protein that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P14151 L-selectin (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein An L-selectin that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P14211 calreticulin (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A calreticulin that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P14222 perforin-1 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A perforin-1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P14416 D(2) dopamine receptor (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A D(2) dopamine receptor that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P14719 interleukin-1 receptor-like 1 (mouse) http://purl.obolibrary.org/obo/PR_000008994 interleukin-1 receptor-like 1 An interleukin-1 receptor-like 1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P15306 thrombomodulin (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A thrombomodulin that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P15331 peripherin (mouse) http://purl.obolibrary.org/obo/PR_000013289 peripherin A peripherin that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P15379 CD44 antigen (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A CD44 molecule that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P15655 fibroblast growth factor 2 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A fibroblast growth factor 2 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P15702 leukosialin (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A leukosialin that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P15814 immunoglobulin lambda-like polypeptide 1 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein An immunoglobulin lambda-like polypeptide 1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P15918 V(D)J recombination-activating protein 1 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A V(D)J recombination-activating protein 1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P15919 V(D)J recombination-activating protein 1 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A V(D)J recombination-activating protein 1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P15976 erythroid transcription factor (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein An erythroid transcription factor that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P16015 carbonic anhydrase 3 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A carbonic anhydrase 3 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P16045 galectin-1 (mouse) http://purl.obolibrary.org/obo/PR_000009766 galectin-1 A galectin-1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P48318 glutamate decarboxylase 1 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A glutamate decarboxylase 1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P48431 transcription factor SOX-2 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A transcription factor SOX-2 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P48432 transcription factor SOX-2 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A transcription factor SOX-2 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P49238 CX3C chemokine receptor 1 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A CX3C chemokine receptor 1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P49290 eosinophil peroxidase (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein An eosinophil peroxidase that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P49582 neuronal acetylcholine receptor subunit alpha-7 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A neuronal acetylcholine receptor subunit alpha-7 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P49682 C-X-C chemokine receptor type 3 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A C-X-C chemokine receptor type 3 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P49863 granzyme K (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A granzyme K that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P49961 ectonucleoside triphosphate diphosphohydrolase 1 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein An ectonucleoside triphosphate diphosphohydrolase 1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P50114 protein S100-B (mouse) http://purl.obolibrary.org/obo/PR_000014419 protein S100-B A protein S100-B that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P50220 homeobox protein Nkx-2.1 (mouse) http://purl.obolibrary.org/obo/PR_000011241 homeobox protein Nkx-2.1 A homeobox protein Nkx-2.1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P50283 T-cell antigen CD7 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A CD7 molecule that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P50481 LIM/homeobox protein Lhx3 (mouse) http://purl.obolibrary.org/obo/PR_000009793 LIM/homeobox protein Lhx3 A LIM/homeobox protein Lhx3 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P51449 nuclear receptor ROR-gamma (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A nuclear receptor ROR-gamma that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P51450 nuclear receptor ROR-gamma (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A nuclear receptor ROR-gamma that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P51450-2 nuclear receptor ROR-gamma isoform 2 (mouse) http://purl.obolibrary.org/obo/PR_P51450 nuclear receptor ROR-gamma (mouse) A nuclear receptor ROR-gamma isoform 2 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P51675 C-C chemokine receptor type 1 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A C-C chemokine receptor type 1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P51677 C-C chemokine receptor type 3 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A C-C chemokine receptor type 3 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P51678 probable C-C chemokine receptor type 3 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A C-C chemokine receptor type 3 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P51679 C-C chemokine receptor type 4 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A C-C chemokine receptor type 4 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P51680 C-C chemokine receptor type 4 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A C-C chemokine receptor type 4 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P51681 C-C chemokine receptor type 5 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A C-C chemokine receptor type 5 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P51682 C-C chemokine receptor type 5 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A C-C chemokine receptor type 5 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P51683 C-C chemokine receptor type 2 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A C-C chemokine receptor type 2 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P51684 C-C chemokine receptor type 6 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A C-C chemokine receptor type 6 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P51885 lumican (mouse) http://purl.obolibrary.org/obo/PR_000009981 lumican A lumican that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P53566 CCAAT/enhancer-binding protein alpha (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A CCAAT/enhancer-binding protein alpha that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q2VLH6 scavenger receptor cysteine-rich type 1 protein M130 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A scavenger receptor cysteine-rich type 1 protein M130 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q5UKY4 cell surface glycoprotein CD200 receptor 3 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A cell surface glycoprotein CD200 receptor 3 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q60651 killer cell lectin-like receptor 4 (mouse) http://purl.obolibrary.org/obo/PR_000009619 killer cell lectin-like receptor 4 A killer cell lectin-like receptor 4 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q60677 integrin alpha-E (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein An integrin alpha-E that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q60682 killer cell lectin-like receptor 8 (mouse) http://purl.obolibrary.org/obo/PR_000009623 killer cell lectin-like receptor 8 A killer cell lectin-like receptor 8 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q60754 macrophage receptor MARCO (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A macrophage receptor MARCO that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q60767 lymphocyte antigen 75 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A lymphocyte antigen 75 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q60805 tyrosine-protein kinase Mer (mouse) http://purl.obolibrary.org/obo/PR_000010329 tyrosine-protein kinase Mer A tyrosine-protein kinase Mer that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q60841 reelin (mouse) http://purl.obolibrary.org/obo/PR_000013879 reelin A reelin that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q61176 arginase-1 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein An arginase-1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q61245 collagen alpha-1(XI) chain (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A collagen alpha-1(XI) chain that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q61391 neprilysin (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A neprilysin that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q61549 adhesion G protein-coupled receptor E1 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein An adhesion G protein-coupled receptor E1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q61575 forkhead box protein N1 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A forkhead box protein N1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q61616 D(1A) dopamine receptor (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A D(1A) dopamine receptor that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q61830 macrophage mannose receptor 1 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A macrophage mannose receptor 1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q61878 bone marrow proteoglycan (mouse) http://purl.obolibrary.org/obo/PR_000013206 bone marrow proteoglycan A bone marrow proteoglycan that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q61878-1 bone marrow proteoglycan isoform 1 (mouse) http://purl.obolibrary.org/obo/PR_Q61878 bone marrow proteoglycan (mouse) A bone marrow proteoglycan isoform 1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q62009 periostin (mouse) http://purl.obolibrary.org/obo/PR_000013031 periostin A periostin that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q8CG65 SCO-spondin (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A SCO-spondin that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q8CJ91 CD209 antigen-like protein B (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A CD209 molecule-like protein B that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q8WTT0 C-type lectin domain family 4 member C (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A C-type lectin domain family 4 member C that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_Q920G3 sialic acid-binding Ig-like lectin 5 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A sialic acid-binding Ig-like lectin 5 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q92954 proteoglycan 4 (human) http://purl.obolibrary.org/obo/PR_000013208 proteoglycan 4 A proteoglycan 4 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_Q9JLV1 BAG family molecular chaperone regulator 3 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A BAG family molecular chaperone regulator 3 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q9JM99 proteoglycan 4 (mouse) http://purl.obolibrary.org/obo/PR_000013208 proteoglycan 4 A proteoglycan 4 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q9Y2I2 netrin-G1 (human) http://purl.obolibrary.org/obo/PR_000011467 netrin-G1 A netrin-G1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_Q9Y5S1 transient receptor potential cation channel subfamily V member 2 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A transient receptor potential cation channel TRPV2 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_Q9Y5Y4 prostaglandin D2 receptor 2 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A prostaglandin D2 receptor DP2 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_Q9Y6W8 inducible T-cell costimulator (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein An inducible T-cell costimulator that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_Q9Z0D9 CX3C chemokine receptor 1 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A CX3C chemokine receptor 1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q9Z0F7 gamma-synuclein (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A gamma-synuclein that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q9Z0J4 nitric oxide synthase 1 (mouse) http://purl.obolibrary.org/obo/PR_000011326 nitric oxide synthase 1 A nitric oxide synthase 1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q9Z2J6 prostaglandin D2 receptor 2 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A prostaglandin D2 receptor DP2 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/CL_0001065 innate lymphoid cell http://purl.obolibrary.org/obo/CL_0000542 lymphocyte A lymphocyte that lacks characteristic T cell, B cell, myeloid cell, and dendritic cell markers, that functions as part of the innate immune response to produce cytokines and other effector responses. http://purl.obolibrary.org/obo/UBERON_0036214 rectosigmoid junction http://purl.obolibrary.org/obo/UBERON_8410024 intestinal junction An anatomical junction that is between the sigmoid colon and rectum. http://purl.obolibrary.org/obo/GO_0140096 catalytic activity, acting on a protein http://purl.obolibrary.org/obo/GO_0003824 catalytic activity Catalytic activity that acts to modify a protein. http://purl.obolibrary.org/obo/GO_0140097 catalytic activity, acting on DNA http://purl.obolibrary.org/obo/GO_0140640 catalytic activity, acting on a nucleic acid Catalytic activity that acts to modify DNA. http://purl.obolibrary.org/obo/GO_0140098 catalytic activity, acting on RNA http://purl.obolibrary.org/obo/GO_0140640 catalytic activity, acting on a nucleic acid Catalytic activity that acts to modify RNA. http://purl.obolibrary.org/obo/GO_0140101 catalytic activity, acting on a tRNA http://purl.obolibrary.org/obo/GO_0140098 catalytic activity, acting on RNA Catalytic activity that acts to modify a tRNA. http://purl.obolibrary.org/obo/GO_0140103 catalytic activity, acting on a glycoprotein http://purl.obolibrary.org/obo/GO_0140096 catalytic activity, acting on a protein Catalysis of a biochemical reaction in which one of the substrates is a glycoprotein. http://purl.obolibrary.org/obo/GO_0106134 positive regulation of cardiac muscle cell contraction http://purl.obolibrary.org/obo/GO_1903116 positive regulation of actin filament-based movement Any process that activates or increases the frequency, rate or extent of cardiac muscle cell contraction. http://purl.obolibrary.org/obo/GO_0140375 immune receptor activity http://purl.obolibrary.org/obo/GO_0038023 signaling receptor activity Receiving a signal and transmitting it in a cell to initiate an immune response. http://purl.obolibrary.org/obo/GO_0140448 signaling receptor ligand precursor processing http://purl.obolibrary.org/obo/GO_0016485 protein processing The cleavage of a peptide bond in a precursor form of a signaling receptor ligand, resulting in the mature (active) form of the ligand. http://purl.obolibrary.org/obo/GO_0062236 ionocyte differentiation http://purl.obolibrary.org/obo/GO_0030855 epithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of an ionocyte. Ionocytes are specialized epithelial cells that contribute to osmotic homeostasis. http://purl.obolibrary.org/obo/GO_0062237 protein localization to postsynapse http://purl.obolibrary.org/obo/GO_0035418 protein localization to synapse Any process in which a protein is transported to, and/or maintained at the postsynapse, the part of a synapse that is part of the post-synaptic cell. http://purl.obolibrary.org/obo/PATO_0070013 spiny stellate cell morphology http://purl.obolibrary.org/obo/PATO_0070026 multipolar neuron morphology A cell morphology that inheres in neurons which have spiny basal dendrites and resemble pyramidal cells but lose their apical dendrites as they mature. Their axons nearly always emerge from the descending side of the soma, but often recurve and ascend with arc-like collaterals. http://purl.obolibrary.org/obo/GO_0140640 catalytic activity, acting on a nucleic acid http://purl.obolibrary.org/obo/GO_0003824 catalytic activity Catalytic activity that acts to modify a nucleic acid. http://purl.obolibrary.org/obo/GO_0140657 ATP-dependent activity http://purl.obolibrary.org/obo/GO_0003674 molecular_function A molecular function characterized by the coupling of ATP hydrolysis to other steps of a reaction mechanism to make the reaction energetically favorable, for example to catalyze a reaction or drive transport against a concentration gradient. http://purl.obolibrary.org/obo/CL_4023089 nest basket cell http://purl.obolibrary.org/obo/CL_2000086 neocortex basket cell A basket cell which has simpler dendritic arbors (compared to small or large basket cells), and an axonal plexus of intermediate density, composed of a few long, smooth axonal branches. http://purl.obolibrary.org/obo/CL_4023051 vascular leptomeningeal cell http://purl.obolibrary.org/obo/CL_4023058 mesothelial fibroblast of the leptomeninx A transcriptomically distinct type of mesothelial fibroblast that is derived from the neural crest, is localized on blood vessels, and is a key component of the pia and arachnoid membranes surrounding the brain. The standard transcriptomic reference data for this cell type can be found on the CellxGene census under the collection: 'Transcriptomic cytoarchitecture reveals principles of human neocortex organization', dataset: 'Supercluster: Non-neuronal cells', Author Categories: 'CrossArea_subclass', clusters VLMC. http://purl.obolibrary.org/obo/GO_0160024 Leydig cell proliferation http://purl.obolibrary.org/obo/GO_0008283 cell population proliferation The multiplication or reproduction of Leydig cells, resulting in the expansion of a cell population. Leydig cells are interstitial cells located adjacent to the seminiferous tubules in the testis which produce testosterone. http://purl.obolibrary.org/obo/CL_0009105 T cell zone reticular cell http://purl.obolibrary.org/obo/CL_0009102 lymph node fibroblastic reticular cell A fibroblastic reticular cell found in the lymph node T cell domain. http://purl.obolibrary.org/obo/CL_0009109 lymphatic endothelial cell of trabecula http://purl.obolibrary.org/obo/CL_0009115 lymph node lymphatic vessel endothelial cell A lymphatic endothelial cell located in a lymph node trabecula. http://purl.obolibrary.org/obo/GO_0140820 cytosol to Golgi apparatus transport http://purl.obolibrary.org/obo/GO_0055085 transmembrane transport The directed movement of substances from the cytosol into the Golgi apparatus of a cell. http://purl.obolibrary.org/obo/CL_0004219 A2 amacrine cell http://purl.obolibrary.org/obo/CL_4030028 glycinergic amacrine cell A bistratifed retinal amacrine cell with a small dendritic field, dendrite stratification in S1-S2, and a second dendrite stratification in S5. This cell type releases the neurotransmitter glycine. http://purl.obolibrary.org/obo/CL_0004245 indoleamine-accumulating amacrine cell http://purl.obolibrary.org/obo/CL_0004253 wide field retinal amacrine cell An amacrine cell with a wide dendritic field and post-synaptic terminals in S5. This cell type releases the neurotransmitters gamma-aminobutyric acid (GABA) and serotonin. http://purl.obolibrary.org/obo/CL_0003006 G4-ON retinal ganglion cell http://purl.obolibrary.org/obo/CL_4023032 ON retinal ganglion cell A G4 retinal ganglion cell that has post sympatic terminals in sublaminar layers S3 and S4 and is depolarized by illumination of its receptive field center. http://purl.obolibrary.org/obo/CL_0003049 M cone cell http://purl.obolibrary.org/obo/CL_0000573 retinal cone cell A cone cell that detects medium wavelength light. Exact peak of spectra detected differs between species. In humans, spectra peaks at 534-545 nm. http://purl.obolibrary.org/obo/CL_0004217 H1 horizontal cell http://purl.obolibrary.org/obo/CL_0000745 retina horizontal cell A horizontal cell with a large cell body, thick dendrites, and a large dendritic arbor. http://purl.obolibrary.org/obo/CL_0004138 retinal ganglion cell A2 http://purl.obolibrary.org/obo/CL_0004117 alpha retinal ganglion cell (Mmus) A retinal ganglion A cell with dense arbor near soma. http://purl.obolibrary.org/obo/CL_0003040 M9 retinal ganglion cell http://purl.obolibrary.org/obo/CL_0000740 retinal ganglion cell A monostratified retinal ganglion cell with large soma and large dendritic field, with medium dendritic arbor, and has dendrites in layers 1 and 5. http://purl.obolibrary.org/obo/CL_0003020 retinal ganglion cell C outer http://purl.obolibrary.org/obo/CL_0004116 retinal ganglion cell C A retinal ganglion cell C that has post-synaptic terminals in S2. http://purl.obolibrary.org/obo/CL_0004251 narrow field retinal amacrine cell http://purl.obolibrary.org/obo/CL_0000561 amacrine cell An amicrine that has a narrow dendritic field. http://purl.obolibrary.org/obo/CL_0004237 fountain amacrine cell http://purl.obolibrary.org/obo/CL_0004252 medium field retinal amacrine cell A retinal amacrine cell with a medium dendritic field and post-synaptic terminals in S1, S2, S3, and S4. This cell type releases the neurotransmitter gamma-aminobutyric acid (GABA). http://purl.obolibrary.org/obo/CL_0004234 diffuse multistratified amacrine cell http://purl.obolibrary.org/obo/CL_0004252 medium field retinal amacrine cell An amacrine cell with a medium dendritic field and post-synaptic terminals in S2, and in S3-S4. http://purl.obolibrary.org/obo/CL_0003050 S cone cell http://purl.obolibrary.org/obo/CL_0000573 retinal cone cell A cone cell that detects short wavelength light. Exact peak of spectra detected differs between species. In humans, spectra peaks at 420-440 nm. http://purl.obolibrary.org/obo/CL_0003018 retinal ganglion cell B3 inner http://purl.obolibrary.org/obo/CL_0004183 retinal ganglion cell B3 A retinal ganglion B3 cell with dentrites terminating in S4. http://purl.obolibrary.org/obo/CL_0003034 M5 retinal ganglion cell http://purl.obolibrary.org/obo/CL_0000740 retinal ganglion cell A monostratified retinal ganglion cell that has a small soma, an assymetric dendritic field with post synaptic terminals in sublaminar layer S3. http://purl.obolibrary.org/obo/CL_0004183 retinal ganglion cell B3 http://purl.obolibrary.org/obo/CL_0004115 retinal ganglion cell B A monostratified retinal ganglion cell with medium soma, sparse dendritic tree, and medium dendritic field. http://purl.obolibrary.org/obo/CL_0003037 M7-ON retinal ganglion cell http://purl.obolibrary.org/obo/CL_4023032 ON retinal ganglion cell An M7 retinal ganglion cells with synaptic terminals in S4 and is depolarized by illumination of its receptive field center. http://purl.obolibrary.org/obo/CL_4023026 direct pathway medium spiny neuron http://purl.obolibrary.org/obo/CL_1001474 medium spiny neuron A GABAergic medium spiny neuron located in the striatum that gives rise to the direct basal ganglia pathway. It projects directly to the GPi and SNr, where it inhibits tonically active GABAergic output neurons to disinhibit thalamic and brainstem motor targets (Gerfen. 2023). In mice and humans, this cell selectively expresses the D1 dopamine receptor (DRD1), which couples to stimulatory G-proteins (Gs/Gαolf) to increase cAMP and activate PKA-dependent signaling cascades (Gerfen et al., 1990; Kebabian & Calne, 1979). Functionally, activation of this cell promotes selected motor actions by disinhibiting thalamic and midbrain motor centers (Mink, 1996; Cui et al., 2013). http://purl.obolibrary.org/obo/CL_4030030 peripheral blood lymphocyte http://purl.obolibrary.org/obo/CL_4030029 blood lymphocyte A blood lymphocyte located in the flowing, circulating blood of the body. http://purl.obolibrary.org/obo/CL_4033000 endothelial cell of venule of lymph node http://purl.obolibrary.org/obo/CL_1000414 endothelial cell of venule A(n) endothelial cell that is part of a(n) venule of lymph node. http://purl.obolibrary.org/obo/UBERON_8600004 visceral muscle tissue http://purl.obolibrary.org/obo/UBERON_0002385 muscle tissue A muscle tissue that is associated with soft internal organs (viscera). http://purl.obolibrary.org/obo/CL_4033023 airway submucosal gland collecting duct epithelial cell http://purl.obolibrary.org/obo/CL_0000066 epithelial cell An epithelial cell that is part of a collecting duct of an airway submucosal gland. http://purl.obolibrary.org/obo/CL_4033025 perichondrial fibroblast http://purl.obolibrary.org/obo/CL_0000057 fibroblast A fibroblast that is part of the fibrous layer of the perichondrium. This cell is responsible for collagen fiber production. http://purl.obolibrary.org/obo/CL_4033019 ON-blue cone bipolar cell http://purl.obolibrary.org/obo/CL_0000749 ON-bipolar cell An ON bipolar cell type with dendrites selectively contacting S-cones. http://purl.obolibrary.org/obo/CL_4033018 lung megakaryocyte http://purl.obolibrary.org/obo/CL_0002320 connective tissue cell A megakaryocyte that is resident in the lung connective tissue. http://purl.obolibrary.org/obo/CL_4033026 lung perichondrial fibroblast http://purl.obolibrary.org/obo/CL_4033025 perichondrial fibroblast A perichondrial fibroblast that is part of the lung. http://purl.obolibrary.org/obo/GO_0141067 intracellular nitrogen homeostasis http://purl.obolibrary.org/obo/GO_0055082 intracellular chemical homeostasis A homeostatic process involved in the maintenance of a steady state level of nitrogen within a cell. http://purl.obolibrary.org/obo/CL_4033046 ON midget ganglion cell http://purl.obolibrary.org/obo/CL_4023032 ON retinal ganglion cell A midget ganglion cell that depolarizes in response to increased light intensity in the center of its receptive field. The majority of input that this cell receives comes from invaginating midget bipolar cells. http://purl.obolibrary.org/obo/CL_4033047 OFF midget ganglion cell http://purl.obolibrary.org/obo/CL_4023188 midget ganglion cell of retina A midget ganglion cell that depolarizes in response to decreased light intensity in the center of its receptive field. The majority of input that this cell receives comes from flat midget bipolar cells. http://purl.obolibrary.org/obo/CL_4033051 OFF parasol ganglion cell http://purl.obolibrary.org/obo/CL_4023189 parasol ganglion cell of retina A parasol ganglion cell that depolarizes in response to decreased light intensity in the center of its receptive field. The majority of input that this cell receives comes from DB3a bipolar cells. http://purl.obolibrary.org/obo/CL_4033052 ON parasol ganglion cell http://purl.obolibrary.org/obo/CL_4023032 ON retinal ganglion cell A parasol ganglion cell that depolarizes in response to increased light intensity in the center of its receptive field. The majority of input that this cell receives comes from DB4 bipolar cells. http://purl.obolibrary.org/obo/CL_4033053 small bistratified retinal ganglion cell http://purl.obolibrary.org/obo/CL_0003001 bistratified retinal ganglion cell A bistratfied retinal ganglion cell with a small dendritic field that has dendrites in the ON and OFF sublamina of the retinal inner plexiform layer and carries blue-ON/yellow-OFF signals. This cell receives bipolar and amacrine input to both the OFF and ON dendritic tree. http://purl.obolibrary.org/obo/CL_4033054 perivascular cell http://purl.obolibrary.org/obo/CL_0000000 cell A cell that is adjacent to a vessel. A perivascular cell plays a crucial role in maintaining vascular function and tissue homeostasis. This cell type regulates vessel integrity and flow dynamics. http://purl.obolibrary.org/obo/CL_4033055 airway submucosal gland duct multiciliated cell http://purl.obolibrary.org/obo/CL_0005012 multiciliated epithelial cell A multi-ciliated epithelial cell located in ciliated duct of an airway submucosal gland, characterized by a columnar shape and motile cilia on its apical surface. http://purl.obolibrary.org/obo/CL_4040004 mesenchymal stem cell of orbital adipose tissue http://purl.obolibrary.org/obo/CL_0002570 mesenchymal stem cell of adipose tissue Any mesenchymal stem cell of adipose tissue that is part of an orbital region. http://purl.obolibrary.org/obo/GO_0170034 L-amino acid biosynthetic process http://purl.obolibrary.org/obo/GO_0170033 L-amino acid metabolic process The chemical reactions and pathways resulting in the formation of L-amino acids, the L-enantiomers of amino acids. http://purl.obolibrary.org/obo/GO_0170035 L-amino acid catabolic process http://purl.obolibrary.org/obo/GO_0170033 L-amino acid metabolic process The chemical reactions and pathways resulting in the breakdown of an L-amino acid. http://purl.obolibrary.org/obo/GO_0170038 proteinogenic amino acid biosynthetic process http://purl.obolibrary.org/obo/GO_0170039 proteinogenic amino acid metabolic process The chemical reactions and pathways resulting in the formation of any amino acid that is incorporated into protein naturally by ribosomal translation of mRNA, and that has a specific codon for translation from mRNA to protein. http://purl.obolibrary.org/obo/GO_0170039 proteinogenic amino acid metabolic process http://purl.obolibrary.org/obo/GO_0006520 amino acid metabolic process The chemical reactions and pathways involving any amino acid that is incorporated into protein naturally by ribosomal translation of mRNA, and that has a specific codon for translation from mRNA to protein. http://purl.obolibrary.org/obo/GO_0170040 proteinogenic amino acid catabolic process http://purl.obolibrary.org/obo/GO_0170039 proteinogenic amino acid metabolic process The chemical reactions and pathways resulting in the breakdown of any amino acid that is incorporated into protein naturally by ribosomal translation of mRNA, and that has a specific codon for translation from mRNA to protein. http://purl.obolibrary.org/obo/GO_0170043 non-proteinogenic amino acid biosynthetic process http://purl.obolibrary.org/obo/GO_0170041 non-proteinogenic amino acid metabolic process The chemical reactions and pathways resulting in the formation of non-proteinogenic amino acids. http://purl.obolibrary.org/obo/GO_0170044 non-proteinogenic amino acid catabolic process http://purl.obolibrary.org/obo/GO_0170041 non-proteinogenic amino acid metabolic process The chemical reactions and pathways resulting in the breakdown of non-proteinogenic amino acids. http://purl.obolibrary.org/obo/GO_0160133 bicarbonate channel activity http://purl.obolibrary.org/obo/GO_0015267 channel activity Enables the energy-independent facilitated diffusion of bicarbonate through a transmembrane aqueous pore or channel. http://purl.obolibrary.org/obo/PATO_0010007 multiciliated http://purl.obolibrary.org/obo/PATO_0001408 ciliated A cellular quality inhering in a bearer by virtue of the bearer's having multiple cilia. http://purl.obolibrary.org/obo/GO_0140001 morula formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The initial formation of a spherical embryonic mass of blastomeres formed before the blastula and resulting from cleavage of the fertilized ovum. http://purl.obolibrary.org/obo/GO_0151001 tuft http://purl.obolibrary.org/obo/GO_0098862 cluster of actin-based cell projections A dense cluster of elongated, thick microvilli on the apical surface of tuft cells in epithelial tissues, such as the intestine and respiratory tract. The apical tuft extends further into the lumen than typical microvilli, featuring larger, more compact projections with unique actin cores that penetrate deep into the cytoplasm, often reaching the perinuclear region. This distinctive structure, rich in microfilaments and microtubules, supports the chemosensory functions of the cell. http://purl.obolibrary.org/obo/GO_0160231 cytospinule http://purl.obolibrary.org/obo/GO_0098858 actin-based cell projection An actin-based cell projection extending laterally from the basolateral membrane of tuft cells in epithelial tissues, including the intestinal epithelium. These thin projections, typically 3-4 per cell and up to 3 micron long, directly contact the nuclei of adjacent epithelial cells, potentially facilitating intercellular communication and molecular exchange. http://purl.obolibrary.org/obo/CL_4300102 STR D2 Gaba indirect pathway medium spiny neuron (Mmus) http://purl.obolibrary.org/obo/CL_4023029 indirect pathway medium spiny neuron A indirect pathway medium spiny neuron of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Adora2a (Mmus), Phactr1 (Mmus), Pcp4l1 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Subclass:062 STR D2 Gaba. http://purl.obolibrary.org/obo/GO_1905951 mitochondrion DNA recombination http://purl.obolibrary.org/obo/GO_0006310 DNA recombination Any DNA recombination that takes place in mitochondrion. http://purl.obolibrary.org/obo/GO_1905955 negative regulation of endothelial tube morphogenesis http://purl.obolibrary.org/obo/GO_1901509 regulation of endothelial tube morphogenesis Any process that stops, prevents or reduces the frequency, rate or extent of endothelial tube morphogenesis. http://purl.obolibrary.org/obo/GO_1905956 positive regulation of endothelial tube morphogenesis http://purl.obolibrary.org/obo/GO_1901509 regulation of endothelial tube morphogenesis Any process that activates or increases the frequency, rate or extent of endothelial tube morphogenesis. http://purl.obolibrary.org/obo/GO_0090741 pigment granule membrane http://purl.obolibrary.org/obo/GO_0030659 cytoplasmic vesicle membrane Any membrane that is part of a pigment granule. http://purl.obolibrary.org/obo/GO_0061880 regulation of anterograde axonal transport of mitochondrion http://purl.obolibrary.org/obo/GO_1902513 regulation of organelle transport along microtubule Any process that modulates the frequency, rate or extent of the directed movement of mitochondria along microtubules in axons away from the cell body and towards the presynapse. http://purl.obolibrary.org/obo/GO_0061881 positive regulation of anterograde axonal transport of mitochondrion http://purl.obolibrary.org/obo/GO_0061880 regulation of anterograde axonal transport of mitochondrion Any process that activates or increasesthe frequency, rate or extent of the directed movement of mitochondria along microtubules in axons away from the cell body and towards the presynapse. http://purl.obolibrary.org/obo/GO_0061882 negative regulation of anterograde axonal transport of mitochondrion http://purl.obolibrary.org/obo/GO_0061880 regulation of anterograde axonal transport of mitochondrion Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of mitochondria along microtubules in axons away from the cell body and towards the presynapse. http://purl.obolibrary.org/obo/GO_0061888 regulation of astrocyte activation http://purl.obolibrary.org/obo/GO_0050865 regulation of cell activation Any process that modulates the frequency, rate or extent of astrocyte activation. http://purl.obolibrary.org/obo/GO_0061889 negative regulation of astrocyte activation http://purl.obolibrary.org/obo/GO_0150079 negative regulation of neuroinflammatory response Any process that decreases the frequency, rate or extent of astrocyte activation. http://purl.obolibrary.org/obo/GO_0061890 positive regulation of astrocyte activation http://purl.obolibrary.org/obo/GO_0150078 positive regulation of neuroinflammatory response Any process that increases the frequency, rate or extent of astrocyte activation. http://purl.obolibrary.org/obo/GO_0150038 postsynaptic dense core vesicle exocytosis http://purl.obolibrary.org/obo/GO_0099003 vesicle-mediated transport in synapse The secretion of molecules (e.g. neuropeptides, insulin-related peptides or neuromodulators such as serotonin and dopamine) contained within a postsynaptic dense core vesicle by fusion of the granule with the plasma membrane of the postsynapse in response to increased cytosolic calcium levels. http://purl.obolibrary.org/obo/GO_0150195 transport across blood-cerebrospinal fluid barrier http://purl.obolibrary.org/obo/GO_0010232 vascular transport The directed movement of substances (e.g. macromolecules, small molecules, ions) through the blood-cerebrospinal fluid barrier. http://purl.obolibrary.org/obo/GO_0150200 regulation of transport across blood-brain barrier http://purl.obolibrary.org/obo/GO_0051049 regulation of transport Any process that modulates the frequency, rate or extent of transport across the blood-brain barrier. http://purl.obolibrary.org/obo/GO_0150201 positive regulation of transport across blood-brain barrier http://purl.obolibrary.org/obo/GO_0150200 regulation of transport across blood-brain barrier Any process that activates or increases the frequency, rate or extent of transport across blood-brain barrier. http://purl.obolibrary.org/obo/GO_0150202 negative regulation of transport across blood-brain barrier http://purl.obolibrary.org/obo/GO_0150200 regulation of transport across blood-brain barrier Any process that stops, prevents or reduces the frequency, rate or extent of transport across blood-brain barrier. http://purl.obolibrary.org/obo/PR_000050032 immunoglobulin complex (human) http://purl.obolibrary.org/obo/GO_0019814 immunoglobulin complex An immunoglobulin complex whose components are encoded in the genome of human. http://purl.obolibrary.org/obo/PR_000050370 H-2 class II histocompatibility antigen, E alpha chain (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein An MHC class II histocompatibility antigen alpha chain DRA that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_000050467 hemoglobin subunit http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human HBA1, HBA2, HBB, HBD, HBE1, HBG1, HBG2, HBM, HBQ1, or HBZ genes, 1:1 orthologs thereof, or semi-orthologs thereof. http://purl.obolibrary.org/obo/PATO_0070009 fan Martinotti morphology http://purl.obolibrary.org/obo/PATO_0070007 Martinotti morphology A Martinotti cell morphology that inheres in neurons which have axons that form a fan-like plexus. http://purl.obolibrary.org/obo/CL_4023090 small basket cell http://purl.obolibrary.org/obo/CL_2000086 neocortex basket cell A basket cell with axonal arbors composed of frequent, short, curvy axonal branches that tend to be near their somata and within the same layer. http://purl.obolibrary.org/obo/CL_0008049 Betz cell http://purl.obolibrary.org/obo/CL_2000049 primary motor cortex pyramidal cell A giant pyramidal neuron with a soma in layer Vb of the primary motor cortex that sends its axons down the spinal cord via the corticospinal tract, either synapsing directly with alpha motor neurons, or targeting interneurons in the spinal cord. In humans, Betz cells are the largest known in the central nervous system. http://purl.obolibrary.org/obo/CL_0009029 mesothelial cell of appendix http://purl.obolibrary.org/obo/CL_0008041 mesothelial cell of intestine A mesothelial cell that is located in a vermiform appendix. http://purl.obolibrary.org/obo/CL_4023071 L5/6 cck GABAergic interneuron (Mmus) http://purl.obolibrary.org/obo/CL_0010011 cerebral cortex GABAergic interneuron A GABAergic cortical interneuron that expresses cck. L5/6 cck cells have soma found mainly in L5 and L6 and have large axonal arborization. http://purl.obolibrary.org/obo/CL_4023080 stellate L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (Mmus) http://purl.obolibrary.org/obo/CL_4023093 stellate pyramidal neuron a L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex that has stellate pyramidal morphology. http://purl.obolibrary.org/obo/CL_4023047 L2/3 intratelencephalic projecting glutamatergic neuron of the primary motor cortex http://purl.obolibrary.org/obo/CL_4030059 L2/3 intratelencephalic projecting glutamatergic neuron An intratelencephalic-projecting glutamatergic neuron with a soma found in cortical layer 2/3 of the primary motor cortex. http://purl.obolibrary.org/obo/CL_0009034 dendritic cell of appendix http://purl.obolibrary.org/obo/CL_0000451 dendritic cell A dendritic cell that is located in a vermiform appendix. http://purl.obolibrary.org/obo/CL_4023076 Martinotti neuron http://purl.obolibrary.org/obo/CL_0011005 GABAergic interneuron An interneuron that has Martinotti morphology. These interneurons are scattered throughout various layers of the cerebral cortex, sending their axons up to the cortical layer I where they form axonal arborization. http://purl.obolibrary.org/obo/CL_0009055 paneth cell of anorectum http://purl.obolibrary.org/obo/CL_0002658 glandular cell of the large intestine A paneth cell that is located in the anorectum. http://purl.obolibrary.org/obo/CL_0009057 anorectum goblet cell http://purl.obolibrary.org/obo/CL_1000320 large intestine goblet cell A goblet cell that is located in the anorectum. http://purl.obolibrary.org/obo/CL_0009058 enterocyte of anorectum http://purl.obolibrary.org/obo/CL_0002071 enterocyte of epithelium of large intestine An enterocyte that is located in the anorectum. http://purl.obolibrary.org/obo/CL_0009063 enteroendocrine cell of anorectum http://purl.obolibrary.org/obo/CL_1001516 intestinal enteroendocrine cell An enteroendocrine cell that is located in the anorectum. http://purl.obolibrary.org/obo/UBERON_8440004 laminar subdivision of the cortex http://purl.obolibrary.org/obo/UBERON_0011215 central nervous system cell part cluster One or a subset of adjacent layers of the neocortex. http://purl.obolibrary.org/obo/CL_4028001 pulmonary capillary endothelial cell http://purl.obolibrary.org/obo/CL_2000016 lung microvascular endothelial cell Any capillary endothelial cell that is part of a lung. http://purl.obolibrary.org/obo/CL_0009085 colony forming unit – Hill cell http://purl.obolibrary.org/obo/CL_0002619 adult endothelial progenitor cell An adult endothelial progenitor cell characterised in vivo by homing to ischemic sites and paracrine support of angiogenesis. They may form discrete colonies. http://purl.obolibrary.org/obo/CL_0009106 medullary reticular cell http://purl.obolibrary.org/obo/CL_0009102 lymph node fibroblastic reticular cell A specialized fibroblast found in the medulla of lymph node. http://purl.obolibrary.org/obo/CL_4030026 BEST4+ enterocyte http://purl.obolibrary.org/obo/CL_0000584 enterocyte An enterocyte of the human intestine expressing bestrophin-4 (BEST4) calcium-activated ion channels. http://purl.obolibrary.org/obo/CL_0003043 M10 retinal ganglion cell http://purl.obolibrary.org/obo/CL_0000740 retinal ganglion cell A monostratified retinal ganglion cell with large soma and large dendritic field, with dense dendritic arbor. http://purl.obolibrary.org/obo/CL_0003032 M3-OFF retinal ganglion cell http://purl.obolibrary.org/obo/CL_4023033 OFF retinal ganglion cell A monostratified retinal ganglion cell that has post synaptic terminals in sublaminar layer S2 and is depolarized by decreased illumination of their receptive field center http://purl.obolibrary.org/obo/CL_0004126 retinal ganglion cell C2 outer http://purl.obolibrary.org/obo/CL_0003020 retinal ganglion cell C outer A retinal ganglion cell C outer that has symmetrical and dense dendritic dendritic tree with a large dendritic field. http://purl.obolibrary.org/obo/CL_4023072 brain vascular cell http://purl.obolibrary.org/obo/CL_0002319 neural cell A cell that is part of the brain vasculature. http://purl.obolibrary.org/obo/UBERON_8600018 neuroendocrine system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system A regulatory system of the body that integrates the nervous system and the endocrine system. This system is formed by specialized neuroendocrine cells located mainly in the nervous system and neuroendocrine glands. However, they can also be found as either single cells or small clusters of cells dispersed throughout the surface epithelium of different tissues. The neuroendocrine system functions through the release of neurotransmitters and neurohormones, enabling communication between the endocrine and nervous systems to govern vitally important processes that include growth, reproduction, metabolism and energy homeostasis, electrolyte and water balance, and responses to stress. http://purl.obolibrary.org/obo/CL_4040006 dermal chromatophore http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell A chromatophore that is part of the dermis. http://purl.obolibrary.org/obo/CL_4042001 TAC3-positive striatal interneuron http://purl.obolibrary.org/obo/CL_0011005 GABAergic interneuron A GABAergic interneuron that has its soma located in the striatum and that has an enriched expression of the genes TAC3 and LHX6. http://purl.obolibrary.org/obo/CL_4042002 TAC3-positive medium spiny neuron http://purl.obolibrary.org/obo/CL_4030051 nucleus accumbens shell and olfactory tubercle D1 medium spiny neuron A nucleus accumbens shell and olfactory tubercle D1 medium spiny neuron that co-expresses TAC3 and the DRD1 receptor. http://purl.obolibrary.org/obo/CL_4042003 border associated macrophage http://purl.obolibrary.org/obo/CL_0000878 central nervous system macrophage A central nervous system macrophage that is part of a choroid plexus, a meninx and a perivascular space. A border associated macrophage interacts with various components of the CNS vasculature and meninges, it participates in immune surveillance and in the regulation of the blood brain barrier. http://purl.obolibrary.org/obo/CL_4042004 choroid epiplexus macrophage http://purl.obolibrary.org/obo/CL_0000880 choroid plexus macrophage A choroid plexus macrophage that is part of the apical surface of some choroid plexus epithelium. This macrophage has a star-like shaped body. http://purl.obolibrary.org/obo/CL_4042005 stromal choroid plexus macrophage http://purl.obolibrary.org/obo/CL_0000880 choroid plexus macrophage A choroid plexus macrophage that is part of a choroid plexus stroma. http://purl.obolibrary.org/obo/CL_4042006 dural macrophage http://purl.obolibrary.org/obo/CL_4042003 border associated macrophage A border associated macrophage which is part of a dura matter. This macrophage phagocytoses intruding pathogens and foreign molecules detected in the bloodstream or in the cerebrospinal fluid. This cell has an amoeboid body with dynamic protrusions in homeostasis. http://purl.obolibrary.org/obo/CL_0008041 mesothelial cell of intestine http://purl.obolibrary.org/obo/CL_0000077 mesothelial cell A mesothelial cell that is part of the intestinal serosa. http://purl.obolibrary.org/obo/CL_4033094 age-associated B cell http://purl.obolibrary.org/obo/CL_0000787 memory B cell A transcriptionally distinct memory B cell whose presence increases with age, during infections, and in autoimmune diseases. In humans and mice, this cell type can be identified by the expression of T-bet, CD11c, CD11b, and the lack of CD21. An age-associated B cell responds to TLR stimuli, may produce autoantibodies, and participates in antiviral responses and pathogen clearance. http://purl.obolibrary.org/obo/CL_4033095 diffuse bipolar 4a cell http://purl.obolibrary.org/obo/CL_0000749 ON-bipolar cell An ON bipolar cell that has high expression of DIRC3, KCNJ3, LINC01915, PTPRK compared with other bipolar cells. http://purl.obolibrary.org/obo/CL_4033096 diffuse bipolar 4b cell http://purl.obolibrary.org/obo/CL_0000749 ON-bipolar cell An ON bipolar cell that has high expression of NOS1AP compared with other bipolar cells. http://purl.obolibrary.org/obo/CL_4047037 stomach smooth muscle inner oblique layer cell http://purl.obolibrary.org/obo/CL_4047034 smooth muscle cell of stomach A smooth muscle cell found in the innermost layer of the muscularis externa of the stomach wall. This cell forms a unique layer of smooth muscle fibers oriented obliquely to the stomach's longitudinal axis. It is responsible for aiding in the mixing and churning of gastric contents, contributing to mechanical digestion within the stomach. http://purl.obolibrary.org/obo/CL_4047040 smooth muscle circular layer cell http://purl.obolibrary.org/obo/CL_0000192 smooth muscle cell A smooth muscle cell that is found in the inner muscular layer of hollow organs. It is characterized by its spiral/helical arrangement around organ lumens. This cell is crucial for peristaltic movements in organs. http://purl.obolibrary.org/obo/CL_4047043 type 1 submucosal plexus glia http://purl.obolibrary.org/obo/CL_4040002 enteroglial cell An enteric glial cell that is associated with neuron cell bodies within submucosal ganglia of the gastrointestinal tract. This cell is located in the submucosa, a layer of connective tissue beneath the intestinal mucosa. This cell plays a role in modulating secretomotor neuron activity and contributes to the regulation of digestive fluid secretion and absorption. http://purl.obolibrary.org/obo/CL_4052032 granzyme H-associated CD8 T cell http://purl.obolibrary.org/obo/CL_0000909 CD8-positive, alpha-beta memory T cell A CD8 T cell characterized by high expression of Granzyme H (GZMH). This cell exhibits a restricted TCR repertoire and elevated expression of cytotoxic, exhaustion, and type I interferon-stimulated gene signatures compared to controls. http://purl.obolibrary.org/obo/CL_4052033 biliary tuft cell http://purl.obolibrary.org/obo/CL_0002204 tuft cell A tuft cell that is part of the extrahepatic biliary tree, including the gallbladder and extrahepatic bile ducts. It shares a core genetic program with intestinal tuft cells but has unique tissue-specific genes. Biliary tuft cell functions as a bile acid-sensitive regulator, suppressing inflammation and modulating microbiome-dependent neutrophil infiltration in biliary tissues. Unlike its intestinal counterparts, this cell decreases in number postnatally as bile acid production matures, with its abundance negatively regulated by bile acids. http://purl.obolibrary.org/obo/CL_4052034 tuft cell of thymus http://purl.obolibrary.org/obo/CL_0002365 medullary thymic epithelial cell A tuft cell that is part of the medullary epithelium of the thymus, characterized by lateral microvilli and specific markers, including L1CAM in both mice (Zhang et al., 2022) and humans (Sun et al., 2023), as well as MHC II in mice (Miller et al., 2018). This cell is pivotal in immune functions such as antigen presentation, central tolerance, and type 2 immunity. A tuft cell in the thymus exhibits characteristics of both a medullary thymic epithelial cell (mTEC) and a peripheral tuft cell. Its development is governed by transcription factors such as POU2F3. http://purl.obolibrary.org/obo/CL_4052035 tuft cell of pancreatic duct http://purl.obolibrary.org/obo/CL_1001433 epithelial cell of exocrine pancreas A tuft cell that is part of the epithelium of pancreatic duct. Present in humans and rats, this cell is absent in the murine pancreas under normal conditions but emerges during acinar-to-ductal metaplasia triggered by injury, inflammation, or oncogenic mutations. It modulates the immune response and protects against pancreatic ductal adenocarcinoma progression by producing suppressive eicosanoids, such as prostaglandin D2. A tuft cell in the pancreatic duct highly expresses the transcription factor POU2F3, which is essential for its development and presence. http://purl.obolibrary.org/obo/CL_4052036 tuft cell of nasal cavity http://purl.obolibrary.org/obo/CL_0002631 epithelial cell of upper respiratory tract A tuft cell that is part of the nasal cavity epithelium, located in both the respiratory and olfactory epithelia of the nose. This cell plays key roles in chemosensation, lipid mediator production, immune responses, and epithelial homeostasis. http://purl.obolibrary.org/obo/CL_4052037 tuft cell of olfactory epithelium http://purl.obolibrary.org/obo/CL_4052036 tuft cell of nasal cavity A tuft cell that is part of the olfactory epithelium, characterized by a globular body and the expression of neurogranin (Nrgn) in mice. This cell plays a crucial role in allergen recognition and regulating olfactory stem cell proliferation via TRPM5-dependent ATP sensing and cysteinyl leukotriene production. Unlike nasal respiratory tuft cells, it has low to absent expression of taste receptors, including the G protein Gα gustducin, and rarely contacts olfactory sensory neurons directly. http://purl.obolibrary.org/obo/CL_4052038 tuft cell of nasal cavity respiratory epithelium http://purl.obolibrary.org/obo/CL_4052036 tuft cell of nasal cavity A tuft cell that is part of the nasal cavity respiratory epithelium. Acting as a chemosensor, it detects bitter taste ligands and bacterial signals via taste receptors, maintaining epithelial-microbial homeostasis by stimulating antimicrobial peptide secretion from adjacent epithelial cells. This cell is a major source of IL-25, promoting type 2 immune responses and potentially contributing to chronic rhinosinusitis (O'Leary et al., 2019). http://purl.obolibrary.org/obo/UBERON_0035036 naris epithelium http://purl.obolibrary.org/obo/UBERON_0000483 epithelium An epithelium that is part of a naris [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0035118 material entity in digestive tract http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure Any material entity that is located in the digestive tract. This includes undigested food and liquid as well as unexcreted waste products. It also includes other entities such as ingested stones used to aid digestion. Any microbial cells or cell populations are also included. http://purl.obolibrary.org/obo/UBERON_0035814 pericardial fat http://purl.obolibrary.org/obo/UBERON_0035818 visceral fat The sum of epicardial and paracardial fat deposits. http://purl.obolibrary.org/obo/UBERON_0035818 visceral fat http://purl.obolibrary.org/obo/UBERON_0001013 adipose tissue Any fat deposit surrounding a visceral organ. http://purl.obolibrary.org/obo/UBERON_0036146 cardiopharyngeal field http://purl.obolibrary.org/obo/UBERON_0007688 anlage An region of the mesoderm that includes anterior lateral mesoderm of the first heart field plus contiguous pharyngeal mesoderm that gives rise to second-heart-field-derived regions of the heart and branchiomeric muscles. http://purl.obolibrary.org/obo/UBERON_0036150 skin appendage follicle http://purl.obolibrary.org/obo/UBERON_0000063 organ subunit An organ subunit in the skin that gives rise to cutaneous appendage. http://purl.obolibrary.org/obo/UBERON_0034947 gas in respiratory system http://purl.obolibrary.org/obo/UBERON_0034873 bodily gas Any portion of gas located in a part of the respiratory system. http://purl.obolibrary.org/obo/UBERON_0035159 entire surface of organism http://purl.obolibrary.org/obo/UBERON_0006984 anatomical surface Anatomical surface, which is the external surface of the whole body. Examples: There is only one body surface. http://purl.obolibrary.org/obo/UBERON_0035174 right ear http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure The organ of hearing located on the right side of the head. http://purl.obolibrary.org/obo/UBERON_0035295 left ear http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure The organ of hearing located on the left side of the head[ncit,modified]. http://purl.obolibrary.org/obo/GO_0110011 regulation of basement membrane organization http://purl.obolibrary.org/obo/GO_1903053 regulation of extracellular matrix organization Any process that modulates the frequency, rate or extent of the assembly, disassembly or arrangement of constituent parts of the basement membrane. http://purl.obolibrary.org/obo/GO_0140021 mitochondrial ADP transmembrane transport http://purl.obolibrary.org/obo/GO_1901679 nucleotide transmembrane transport The process in which ADP is transported across a mitochondrial membrane, into or out of the mitochondrion. http://purl.obolibrary.org/obo/GO_0120031 plasma membrane bounded cell projection assembly http://purl.obolibrary.org/obo/GO_0030031 cell projection assembly Formation of a prolongation or process extending and that is bounded by plasma membrane, e.g. a cilium, lamellipodium, or axon. http://purl.obolibrary.org/obo/GO_0120035 regulation of plasma membrane bounded cell projection organization http://purl.obolibrary.org/obo/GO_0031344 regulation of cell projection organization Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of plasma membrane bounded cell projections. http://purl.obolibrary.org/obo/GO_0106014 regulation of inflammatory response to wounding http://purl.obolibrary.org/obo/GO_0050727 regulation of inflammatory response Any process that modulates the frequency, rate or extent of the inflammatory response to wounding. http://purl.obolibrary.org/obo/GO_0106015 negative regulation of inflammatory response to wounding http://purl.obolibrary.org/obo/GO_0106014 regulation of inflammatory response to wounding Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response to wounding. http://purl.obolibrary.org/obo/GO_0106016 positive regulation of inflammatory response to wounding http://purl.obolibrary.org/obo/GO_0106014 regulation of inflammatory response to wounding Any process that activates or increases the frequency, rate or extent of the inflammatory response to wounding. http://purl.obolibrary.org/obo/GO_0104004 cellular response to environmental stimulus http://purl.obolibrary.org/obo/GO_0051716 cellular response to stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an environmental stimulus. http://purl.obolibrary.org/obo/GO_0099182 presynaptic intermediate filament cytoskeleton http://purl.obolibrary.org/obo/GO_0099569 presynaptic cytoskeleton The intermediate filament cytoskeleton that is part of a presynapse. http://purl.obolibrary.org/obo/GO_0110096 cellular response to aldehyde http://purl.obolibrary.org/obo/GO_1901701 cellular response to oxygen-containing compound Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aldehyde stimulus. http://purl.obolibrary.org/obo/GO_0062056 compound eye pigment cell differentiation http://purl.obolibrary.org/obo/GO_0050931 pigment cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a compound eye pigment cell, a cell of the retina containing screening pigments that functions to screen photoreceptors from light leaking from adjacent ommatidia. http://purl.obolibrary.org/obo/GO_0150076 neuroinflammatory response http://purl.obolibrary.org/obo/GO_0006954 inflammatory response The immediate defensive reaction by neural vertebrate tissue to infection or injury caused by chemical or physical agents. http://purl.obolibrary.org/obo/GO_0150078 positive regulation of neuroinflammatory response http://purl.obolibrary.org/obo/GO_0050729 positive regulation of inflammatory response Any process that activates or increases the frequency, rate or extent of neuroinflammatory response. http://purl.obolibrary.org/obo/GO_0150079 negative regulation of neuroinflammatory response http://purl.obolibrary.org/obo/GO_0050728 negative regulation of inflammatory response Any process that stops, prevents or reduces the frequency, rate or extent of neuroinflammatory response. http://purl.obolibrary.org/obo/GO_0140354 lipid import into cell http://purl.obolibrary.org/obo/GO_0006869 lipid transport The directed movement of a lipid from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis. http://purl.obolibrary.org/obo/GO_0150117 positive regulation of cell-substrate junction organization http://purl.obolibrary.org/obo/GO_0150116 regulation of cell-substrate junction organization Any process that activates or increases the frequency, rate or extent of cell-substrate junction organization. http://purl.obolibrary.org/obo/GO_0150118 negative regulation of cell-substrate junction organization http://purl.obolibrary.org/obo/GO_0150116 regulation of cell-substrate junction organization Any process that stops, prevents or reduces the frequency, rate or extent of cell-substrate junction organization. http://purl.obolibrary.org/obo/CL_0001200 lymphocyte of B lineage, CD19-positive http://purl.obolibrary.org/obo/CL_0000945 lymphocyte of B lineage A lymphocyte of B lineage that is CD19-positive. http://purl.obolibrary.org/obo/CL_0001201 B cell, CD19-positive http://purl.obolibrary.org/obo/CL_0001200 lymphocyte of B lineage, CD19-positive A B cell that is CD19-positive. http://purl.obolibrary.org/obo/CL_0001202 CD86-positive plasmablast http://purl.obolibrary.org/obo/CL_0000980 plasmablast A plasmablast that is CD86-positive. http://purl.obolibrary.org/obo/CL_0001203 CD8-positive, alpha-beta memory T cell, CD45RO-positive http://purl.obolibrary.org/obo/CL_0000909 CD8-positive, alpha-beta memory T cell A CD8-positive, alpha-beta T cell with memory phenotype indicated by being CD45RO and CD127-positive. This cell type is also described as being CD25-negative. http://purl.obolibrary.org/obo/CL_0001204 CD4-positive, alpha-beta memory T cell, CD45RO-positive http://purl.obolibrary.org/obo/CL_0000897 CD4-positive, alpha-beta memory T cell CD4-positive, alpha-beta long-lived T cell with the phenotype CD45RO-positive and CD127-positive. This cell type is also described as being CD25-negative. http://purl.obolibrary.org/obo/CL_0008033 decidual pericyte http://purl.obolibrary.org/obo/CL_2000078 placental pericyte A pericyte of the decidual vasculature. http://purl.obolibrary.org/obo/CL_0008034 mural cell http://purl.obolibrary.org/obo/CL_4033054 perivascular cell Mural cells are pericytes and the vascular smooth muscle cells (vSMCs) of the microcirculation. http://purl.obolibrary.org/obo/CL_0008035 microcirculation associated smooth muscle cell http://purl.obolibrary.org/obo/CL_0008034 mural cell Any vascular associated smooth muscle cell that is part of some microcirculatory vessel. http://purl.obolibrary.org/obo/CL_0008036 extravillous trophoblast http://purl.obolibrary.org/obo/CL_0000351 trophoblast cell A trophoblast cell that is not part of a placental villous. http://purl.obolibrary.org/obo/CL_0011017 vagal neural crest cell http://purl.obolibrary.org/obo/CL_0011012 neural crest cell Cell that is part of the vagal neural crest population. The vagal neural crest arises from the axial level of somites 1-7 and has been described as a hybrid between the head and the trunk populations. http://purl.obolibrary.org/obo/CL_0011020 neural progenitor cell http://purl.obolibrary.org/obo/CL_0011026 progenitor cell An undifferentiated cell derived from a neural stem cell, with a limited capacity to self-renew (Dibajnia and Morshead, 2013) and the ability to generate multiple types of lineage-restricted progenitors, contributing to the formation of neurons, astrocytes, and oligodendrocytes. http://purl.obolibrary.org/obo/CL_0017000 pulmonary ionocyte http://purl.obolibrary.org/obo/CL_0005006 ionocyte An ionocyte that is part of the lung epithelium. The cells from this type are major sources of the CFTR protein in human and mice. http://purl.obolibrary.org/obo/CL_0017001 splanchnic mesodermal cell http://purl.obolibrary.org/obo/CL_0011010 lateral mesodermal cell A mesodermal cell that is part of the splanchnic layer of lateral plate mesoderm. http://purl.obolibrary.org/obo/PATO_0070018 tufted pyramidal morphology http://purl.obolibrary.org/obo/PATO_0070017 standard pyramidal morphology A pyramidal cell morphology that inheres in neurons which have a distinct tuft formation, distal from the soma. http://purl.obolibrary.org/obo/PATO_0070015 pyramidal family morphology http://purl.obolibrary.org/obo/PATO_0070026 multipolar neuron morphology A cell morphology that inheres in neurons which have a pyramidal shaped soma, a single axon, a large apical dendrite and multiple basal dendrites. http://purl.obolibrary.org/obo/CL_4023046 L6b glutamatergic neuron of the primary motor cortex http://purl.obolibrary.org/obo/CL_4023038 L6b glutamatergic cortical neuron An excitatory glutamatergic neuron transcriptomically related to the CT subclass, with a soma preferentially located in the bottom of L6 of the primary motor cortex. http://purl.obolibrary.org/obo/CL_4023095 untufted pyramidal neuron http://purl.obolibrary.org/obo/CL_0000598 pyramidal neuron A pyramidal neuron which lacks a clear tuft formation but extends to large radial distances. http://purl.obolibrary.org/obo/GO_0120327 telopode http://purl.obolibrary.org/obo/GO_0120025 plasma membrane bounded cell projection A telopode is a plasma membrane bounded cell projection that is present on a telocyte and is tens to hundreds of microns long. Telopodes form a labyrinthine system communicating through gap junctions. http://purl.obolibrary.org/obo/CL_0017500 neutrophillic cytoplasm http://purl.obolibrary.org/obo/GO_0005737 cytoplasm Cytoplasm that exhibits a characteristic staining and color, pale-pink, with Wright-Giemsa stain. http://purl.obolibrary.org/obo/CL_0017502 acidophilic cytoplasm http://purl.obolibrary.org/obo/GO_0005737 cytoplasm Cytoplasm that exhibits a characteristic staining and color, red or pink, with Eosin stain. http://purl.obolibrary.org/obo/CL_0017503 basophilic cytoplasm http://purl.obolibrary.org/obo/GO_0005737 cytoplasm Cytoplasm that exhibits molecular interaction for basic dyes under specific pH conditions. http://purl.obolibrary.org/obo/CL_0017504 polychromatophilic cytoplasm http://purl.obolibrary.org/obo/GO_0005737 cytoplasm Cytoplasm that exhibits affinity for both basic and acid stains under specific pH conditions. http://purl.obolibrary.org/obo/CL_0017507 reniform nucleus http://purl.obolibrary.org/obo/GO_0005634 nucleus A concave nucleus shape where the indentation is smaller than half of the distance to the farthest nuclear margin. http://purl.obolibrary.org/obo/CL_0017509 alobate nucleus http://purl.obolibrary.org/obo/GO_0005634 nucleus Any nucleus that has characteristic some alobate. http://purl.obolibrary.org/obo/UBERON_8410077 airway submucosal gland http://purl.obolibrary.org/obo/UBERON_0036225 respiratory system gland A submucosal gland found in a respiratory tract. http://purl.obolibrary.org/obo/UBERON_0039856 right ovarian vein http://purl.obolibrary.org/obo/UBERON_0001145 ovarian vein Ovarian vein, each instance of which is a tributary of some inferior vena cava that drains the right pampiniform plexus of some broad ligament. http://purl.obolibrary.org/obo/UBERON_0039857 left ovarian vein http://purl.obolibrary.org/obo/UBERON_0001145 ovarian vein Ovarian vein, each instance of which is a tributary of some left renal vein that drains the left pampiniform plexus of some broad ligament. http://purl.obolibrary.org/obo/UBERON_8440008 periventricular hypothalamic nucleus, intermediate part http://purl.obolibrary.org/obo/UBERON_0006568 hypothalamic nucleus The intermediate part of the periventricular hypothalamic nucleus. http://purl.obolibrary.org/obo/UBERON_8440012 cerebral nuclei http://purl.obolibrary.org/obo/UBERON_0009663 telencephalic nucleus One of three components of the cerebrum that is a composite structure of the endbrain defined on the basis of origin from the ventricular ridge of the embryonic Encephalon. It consists of the extended striatum and the extended pallidum. http://purl.obolibrary.org/obo/UBERON_8440030 striatum-like amygdalar nuclei http://purl.obolibrary.org/obo/UBERON_0009663 telencephalic nucleus A part of the striatum which is primarilly composed of amygdalar areas. The sAMY is composed of the anterior amygdalar area, central amygdalar nucleus, intercalated amygdalar nucleus, medial amygdalar nucleus, and the bed nucleus of the accessory olfactory tract. http://purl.obolibrary.org/obo/UBERON_8440043 superior paraolivary nucleus http://purl.obolibrary.org/obo/UBERON_0007247 nucleus of superior olivary complex A structure embedded in the superior olivary complex that is driven by input pathways from the octopus cells in the cochlear nucleus and the neurons of the medial nucleus of the trapezoid body. http://purl.obolibrary.org/obo/CL_0017005 lymphoblast http://purl.obolibrary.org/obo/CL_0000542 lymphocyte A lymphocyte that has gotten larger after being stimulated by an antigen. http://purl.obolibrary.org/obo/CL_4030027 GABAergic amacrine cell http://purl.obolibrary.org/obo/CL_0011005 GABAergic interneuron An amacrine cell that uses GABA as a neurotransmitter. http://purl.obolibrary.org/obo/CL_4030028 glycinergic amacrine cell http://purl.obolibrary.org/obo/CL_1001509 glycinergic neuron An amacrine cell that uses glycine as a neurotransmitter. http://purl.obolibrary.org/obo/CL_0003004 G3 retinal ganglion cell http://purl.obolibrary.org/obo/CL_0003001 bistratified retinal ganglion cell A bistratified retinal ganglion cell that has a small dendritic field with sparse density that terminates at the intersection of the S4-S5 sublaminar level, and a second dendrite field that is medium in size and degree of arborization that terminates in sublaminar layer S2. http://purl.obolibrary.org/obo/CL_0003001 bistratified retinal ganglion cell http://purl.obolibrary.org/obo/CL_0004247 bistratified cell A retinal ganglion cell that has dendrites stratified in two layers of the inner-plexiform layer. http://purl.obolibrary.org/obo/PATO_0070063 monostratified dendrite cell morphology http://purl.obolibrary.org/obo/PATO_0010006 cell morphology A cell morphology that inheres in neurons with dendrites that stratify at one and only one location. http://purl.obolibrary.org/obo/GO_0140962 multicellular organismal-level chemical homeostasis http://purl.obolibrary.org/obo/GO_0048878 chemical homeostasis A homeostatic process involved in the maintenance of a steady state level of a chemical within extracellular body fluids, such as blood, xylem or phloem, of a multicellular organism. This is distinct from maintenance of cellular homeostasis, which occurs within a cell. http://purl.obolibrary.org/obo/CL_4033001 endothelial cell of arteriole of lymph node http://purl.obolibrary.org/obo/CL_1000412 endothelial cell of arteriole A(n) endothelial cell that is part of a(n) arteriole of lymph node. http://purl.obolibrary.org/obo/STATO_0000607 proportion http://purl.obolibrary.org/obo/STATO_0000184 ratio a proportion is a ratio which corresponds to the fraction of the total presenting a particular feature http://purl.obolibrary.org/obo/STATO_0000610 measure of association http://purl.obolibrary.org/obo/STATO_0000039 statistic measure of association is a statistic which quantitatively represents a relationship between two or more variables http://purl.obolibrary.org/obo/STATO_0000623 measure of agreement http://purl.obolibrary.org/obo/STATO_0000610 measure of association A measure of association of two variables representing measurements of the same attribute of an entity. http://purl.obolibrary.org/obo/CL_4033126 sacral ganglion TH neuron http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron A sympathetic neuron that has the soma located in the sacral ganglion and expresses the marker tyrosine hydroxylase (TH). http://purl.obolibrary.org/obo/CL_4301591 Astro-TE NN_1 astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4300359 astrocyte of cerebrum (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Myoc (Mmus), Camk2a (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1161 Astro-TE NN_1. http://purl.obolibrary.org/obo/CL_4307083 hypendemal cell (Mmus) http://purl.obolibrary.org/obo/CL_4023181 hypendymal cell A hypendymal cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Sspo (Mmus), Wfdc2 (Mmus). It is distinguished from other Astro-Epen cells by expression of Sspo, Wfdc2. These cells are located in the Midbrain, brain , in or close to the regions: third ventricle, posterior commissure, Subcommissural organ . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5263 Hypendymal NN_1. http://purl.obolibrary.org/obo/CL_4072008 A11 dopaminergic neuron http://purl.obolibrary.org/obo/CL_0012001 neuron of the forebrain A type of hypothalamic dopaminergic neuron found in the posterior hypothalamus, projecting to the spinal cord where it modulates pain, motor activity (Koblinger et al., 2014), and somatosensory processing (Zhang et a., 2023). http://purl.obolibrary.org/obo/CL_4072007 A10 dopaminergic neuron http://purl.obolibrary.org/obo/CL_2000097 midbrain dopaminergic neuron A type of dopaminergic neuron found in the ventral tegmental area that is involved in reward processes, motivation and addiction. http://purl.obolibrary.org/obo/CL_4072012 A15 dopaminergic neuron http://purl.obolibrary.org/obo/CL_0012001 neuron of the forebrain A type of dopaminergic neuron located in the preoptic periventricular nucleus of the hypothalamus and implicated in neuroendocrine modulation. http://purl.obolibrary.org/obo/CL_4307036 Astro-NT NN_2 Fam227b astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301590 Astro-NT NN_2 astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Slc7a10 (Mmus), Cyp26b1 (Mmus), Igfbp2 (Mmus), Shroom3 (Mmus). It is distinguished from other Astro-NT NN_2 cells by expression of Fam227b, Shroom3. These cells are located in the Midbrain, Medulla, Pons . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5216 Astro-NT NN_2. http://purl.obolibrary.org/obo/CL_4300351 CBX MLI Megf11 Gaba molecular layer interneuron (Mmus) http://purl.obolibrary.org/obo/CL_4300028 cerebellar GABAergic neuron (Mmus) A molecular layer interneuron of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Homer3 (Mmus), Tfap2b (Mmus), Sorcs3 (Mmus), Cacna1e (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Subclass:311 CBX MLI Megf11 Gaba. http://purl.obolibrary.org/obo/CL_4072003 mature myelinating oligodendrocyte http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure A post-mitotic oligodendrocyte derived from a myelin-forming oligodendrocyte (MFOL). A mature Myelinating Oligodendrocyte is a fully differentiated cell that is actively engaged in myelination. In addition to high expression of canonical myelin genes (e.g., Mbp, Plp1, Mog), a MOL can be distinguished by the expression of stage-enriched genes Grm3, Klk6, Ptgds, Anxa5, and Hopx in mice. These markers reflect the functional specialization of a mature oligodendrocyte, including roles in signalling, lipid metabolism, and myelin maintenance. http://purl.obolibrary.org/obo/CL_4306426 pinealocyte (Mmus) http://purl.obolibrary.org/obo/CL_0000652 pinealocyte A pinealocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Cngb3 (Mmus), Ush2a (Mmus). It is glutamatergic (inferred from expression of Ddc, Slc17a6, Slc17a7). These cells are located in the brain , in or close to the regions: third ventricle . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:4606 Pineal Crx Glut_1. http://purl.obolibrary.org/obo/GO_0140115 export across plasma membrane http://purl.obolibrary.org/obo/GO_0055085 transmembrane transport The directed movement of some substance from inside of a cell, across the plasma membrane and into the extracellular region. http://purl.obolibrary.org/obo/UBERON_0036285 wall of left ventricle http://purl.obolibrary.org/obo/UBERON_0004784 heart ventricle wall Wall of ventricle which is continuous with the wall of aorta. http://purl.obolibrary.org/obo/UBERON_0036286 wall of right ventricle http://purl.obolibrary.org/obo/UBERON_0004784 heart ventricle wall Wall of ventricle which is continuous with the wall of pulmonary trunk. http://purl.obolibrary.org/obo/UBERON_0036294 mucosa of lip http://purl.obolibrary.org/obo/UBERON_0003729 mouth mucosa A mucosa that is part of a lip region [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0150147 cell-cell junction disassembly http://purl.obolibrary.org/obo/GO_0045216 cell-cell junction organization The disaggregation of a cell-cell junction into its constituent components. http://purl.obolibrary.org/obo/GO_0062197 cellular response to chemical stress http://purl.obolibrary.org/obo/GO_0070887 cellular response to chemical stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus indicating the organism is under stress. http://purl.obolibrary.org/obo/GO_0120223 larynx morphogenesis http://purl.obolibrary.org/obo/GO_0009887 animal organ morphogenesis The process in which the larynx is generated and organized. The larynx is a continuation of the pharynx that is involved in breathing, sound production, and protecting the trachea against food aspiration. http://purl.obolibrary.org/obo/GO_0120224 larynx development http://purl.obolibrary.org/obo/GO_0048513 animal organ development The biological process whose specific outcome is the progression of a larynx from an initial condition to its mature state. This process begins with the formation of the larynx and ends with the mature structure. A larynx is a continuation of the pharynx that is involved in breathing, sound production, and protecting the trachea against food aspiration. http://purl.obolibrary.org/obo/PR_000050025 angiotensinogenase http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the mouse Ren1 or Ren2 genes, 1:1 orthologs thereof, or a semi-ortholog thereof. http://purl.obolibrary.org/obo/CL_0011019 mesothelial cell of epicardium http://purl.obolibrary.org/obo/CL_0002494 cardiocyte A mesothelial cell that is part of the epicardium. http://purl.obolibrary.org/obo/CL_0011021 fibroblast of upper back skin http://purl.obolibrary.org/obo/CL_0011022 fibroblast of skin of back A fibroblast that is part of upper back skin. http://purl.obolibrary.org/obo/CL_0011022 fibroblast of skin of back http://purl.obolibrary.org/obo/CL_0002620 skin fibroblast A fibroblast that is part of skin of back. http://purl.obolibrary.org/obo/CL_0011023 CD25+ mast cell http://purl.obolibrary.org/obo/CL_0001063 neoplastic cell A mast cell that is CD25+. http://purl.obolibrary.org/obo/CL_0011024 double negative T regulatory cell http://purl.obolibrary.org/obo/CL_0002489 double negative thymocyte A double negative thymocyte that is CD3-positive, CD4-negative, CD8-negative, that that are present in the periphery in very low numbers and predominantly produce INF-gamma, TNF-alpha, and a low amount of TGF-beta, but not IL-2, IL-4, IL-10 or IL-13 upon activation. http://purl.obolibrary.org/obo/CL_0019001 tracheobronchial serous cell http://purl.obolibrary.org/obo/CL_0000313 serous secreting cell Any serous secreting cell that is part of the tracheobronchial epithelium. http://purl.obolibrary.org/obo/CL_0019002 tracheobronchial chondrocyte http://purl.obolibrary.org/obo/CL_0000138 chondrocyte Any chondrocyte that is part of the tracheobronchial tree. http://purl.obolibrary.org/obo/CL_0019003 tracheobronchial goblet cell http://purl.obolibrary.org/obo/CL_0002370 respiratory tract goblet cell Any goblet cell that is part of the tracheobronchial epithelium. http://purl.obolibrary.org/obo/CL_4023044 non-medulla, extratelencephalic-projecting glutamatergic neuron of the primary motor cortex http://purl.obolibrary.org/obo/CL_2000049 primary motor cortex pyramidal cell An extratelencephalic-projecting glutamatergic neuron located in layer 5b of the primary motor cortex that does not project to the medulla. Non-MY ET cells are large, big-tufted cells with the apical dendrite often bifurcating close to the soma, suggesting they are corticospinal cells. Non-MY ET cells have bigger hyperpolarization sag, lower input resistance, and smaller AP width, compared to L5 IT neurons. http://purl.obolibrary.org/obo/CL_4023041 L5 extratelencephalic projecting glutamatergic cortical neuron http://purl.obolibrary.org/obo/CL_4023111 cerebral cortex pyramidal neuron A transcriptomically distinct glutamatergic neuron, with a soma found in the deeper portion of L5, that has long-range axonal projections including deep subcortical targets outside of the telencephalon and, in some cases, the spinal cord. While the L5 ET neuron projections are not limited to ET targets, they are clearly differentiated from the neuron subclasses whose projections are constrained to intratelencephalic (IT) targets. L5 ET neurons are generally the largest excitatory cortical neurons, typically having a thick apical dendrite with a prominent dendritic tuft in layer 1 and displaying burst-firing physiological characteristics. http://purl.obolibrary.org/obo/CL_4023129 retinoblast http://purl.obolibrary.org/obo/CL_0009004 retinal cell A retinal cell that is immature or undifferentiated. http://purl.obolibrary.org/obo/CL_4030000 choroidal melanocyte http://purl.obolibrary.org/obo/CL_0000148 melanocyte A melanocyte located in the vascular uvea and involved in photoprotection, regulation of oxidative damage and immune responses. http://purl.obolibrary.org/obo/CL_4030002 effector memory CD45RA-positive, alpha-beta T cell, terminally differentiated http://purl.obolibrary.org/obo/CL_0000791 mature alpha-beta T cell An alpha-beta memory T cell with the phenotype CD45RA-positive. http://purl.obolibrary.org/obo/CL_0009102 lymph node fibroblastic reticular cell http://purl.obolibrary.org/obo/CL_0009101 fibroblastic reticular cell A specialized, fibroblastic reticular cell of mesenchymal origin found in lymph nodes. In human, it expresses several markers common to myofibroblasts (desmin, vimentin, CD73, CD90, α-smooth muscle actin (αSMA)), and can be differentiated from endothelial cells by its lack of CD31 expression. These cells are critical for the overall organization and function of the lymph node. Lymph node fibroblastic reticular cells (FRCs) can be further classified based on their location, function, and unique marker expression. http://purl.obolibrary.org/obo/GO_0106426 regulation of kainate selective glutamate receptor signaling pathway http://purl.obolibrary.org/obo/GO_1900449 regulation of glutamate receptor signaling pathway Any process that modulates the frequency, rate or extent of the kainate selective glutamate receptor signaling pathway. http://purl.obolibrary.org/obo/GO_0106427 negative regulation of kainate selective glutamate receptor signaling pathway http://purl.obolibrary.org/obo/GO_0106426 regulation of kainate selective glutamate receptor signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of the kainate selective glutamate receptor signaling pathway. http://purl.obolibrary.org/obo/GO_0106428 positive regulation of kainate selective glutamate receptor signaling pathway http://purl.obolibrary.org/obo/GO_0106426 regulation of kainate selective glutamate receptor signaling pathway Any process that activates or increases the frequency, rate or extent of the kainate selective glutamate receptor signaling pathway. http://purl.obolibrary.org/obo/GO_0140899 plastid gene expression http://purl.obolibrary.org/obo/GO_0010467 gene expression The process in which a plastid gene's sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form. http://purl.obolibrary.org/obo/GO_0160038 somatic sensory system development http://purl.obolibrary.org/obo/GO_0048880 sensory system development The process whose specific outcome is the progression of a somatic sensory system over time from its formation to the mature structure. Somatic sensory system is the sensory system for the sense of touch and pain. http://purl.obolibrary.org/obo/GO_0160048 craniofacial suture closure http://purl.obolibrary.org/obo/GO_0060349 bone morphogenesis The process of fusing together the edges of a craniofacial suture. http://purl.obolibrary.org/obo/CL_0004218 H2 horizontal cell http://purl.obolibrary.org/obo/CL_0000745 retina horizontal cell A horizontal cell with a small cell body, thin dendrites, and small dendritic arbor. http://purl.obolibrary.org/obo/CL_0003008 G5 retinal ganglion cell http://purl.obolibrary.org/obo/CL_0000740 retinal ganglion cell A mono-stratified retinal ganglion cell that has a medium dendritic field and a medium dendritic arbor with post sympatic terminals in sublaminar layer S2. http://purl.obolibrary.org/obo/CL_4023039 amygdala excitatory neuron http://purl.obolibrary.org/obo/CL_0012001 neuron of the forebrain Any neuron that has its soma located in some amygdala and is capable of some glutamate secretion, neurotransmission. http://purl.obolibrary.org/obo/CL_4033013 suprabasal keratinocyte http://purl.obolibrary.org/obo/CL_4052061 epidermal keratinocyte A keratinocyte that resides in the epidermal suprabasal layer and expresses differentiation markers, including keratin 1 and keratin 10, in both humans and mice. In human interfollicular epidermis, this cell retains proliferative capacity and possesses retrodifferentiation potential, acquiring basal-like properties during wound healing or basement membrane contact. http://purl.obolibrary.org/obo/CL_0001066 erythroid progenitor cell, mammalian http://purl.obolibrary.org/obo/CL_0000038 erythroid progenitor cell A progenitor cell committed to the erythroid lineage. This cell is ter119-positive but lacks expression of other hematopoietic lineage markers (lin-negative). http://purl.obolibrary.org/obo/CL_0001070 beige adipocyte http://purl.obolibrary.org/obo/CL_0000136 adipocyte An adipocyte that is beige in color, thermogenic, and which differentiates in white fat tissue from a Myf5-negative progenitor. http://purl.obolibrary.org/obo/CL_0008011 skeletal muscle satellite stem cell http://purl.obolibrary.org/obo/CL_0000594 skeletal muscle satellite cell A skeletal muscle satellite cell that divides by stem cell division. A proportion of this population undergoes symmetric stem cell division, producing two skeletal muscle satellite stem cells. The rest undergo asymmetric stem cell division - retaining their identity while budding off a daughter cell that differentiates into an adult skeletal muscle myoblast. http://purl.obolibrary.org/obo/CL_0008012 quiescent skeletal muscle satellite cell http://purl.obolibrary.org/obo/CL_0000594 skeletal muscle satellite cell A skeletal muscle satellite cell that is mitotically quiescent. These cells are wedge shaped and have a large nuclear to cytoplasmic ratio with few organelles, a small nucleus and condensed interphase chromatin. Satellite cells typically remain in this state until activated following muscle damage. http://purl.obolibrary.org/obo/CL_0008016 activated skeletal muscle satellite cell http://purl.obolibrary.org/obo/CL_0000594 skeletal muscle satellite cell A skeletal muscle satellite cell that has become mitotically active - typically following muscle damage. http://purl.obolibrary.org/obo/CL_0008017 adult skeletal muscle myoblast http://purl.obolibrary.org/obo/CL_0000515 skeletal muscle myoblast A skeletal muscle myoblast that is part of a skeletal mucle. These cells are formed following acivation and division of skeletal muscle satellite cells. They form a transient population that is lost when they fuse to form skeletal muscle fibers. http://purl.obolibrary.org/obo/CL_0008018 somatic muscle myoblast http://purl.obolibrary.org/obo/CL_0000056 myoblast A myoblast that is commited to developing into a somatic muscle. http://purl.obolibrary.org/obo/CL_0008019 mesenchymal cell http://purl.obolibrary.org/obo/CL_0000219 motile cell A non-polarised cell precursor cell that is part of some mesenchyme, is associated with the cell matrix but is not connected to other cells and is capable of migration. http://purl.obolibrary.org/obo/CL_0008020 skeletal muscle satellite myogenic cell http://purl.obolibrary.org/obo/CL_0000594 skeletal muscle satellite cell A skeletal muscle satellite cell that undergoes symmetric division to produce two adult skeleltal muscle myoblasts. http://purl.obolibrary.org/obo/CL_0008021 anterior lateral line ganglion neuron http://purl.obolibrary.org/obo/CL_2000031 lateral line ganglion neuron Any peripheral nervous system neuron that has its soma located in some anterior lateral line ganglion. http://purl.obolibrary.org/obo/CL_0008022 endocardial cushion cell http://purl.obolibrary.org/obo/CL_0002494 cardiocyte A mesenchymal cell of the endocardial cushion. These cells develop via an epithelial to mesenchymal transition when endocardial cells break cell-to-cell contacts and migrate into the cardiac jelly. Cells from this population form the heart septa and valves. http://purl.obolibrary.org/obo/CL_0008025 noradrenergic neuron http://purl.obolibrary.org/obo/CL_4033050 catecholaminergic neuron A neuron that release noradrenaline (noriphinephrine) as a neurotransmitter. http://purl.obolibrary.org/obo/CL_0008026 open tracheal system tracheocyte http://purl.obolibrary.org/obo/CL_0000066 epithelial cell An epithelial cell that is part of the epithelium of a tracheal tube in an open tracheal system, such as that found in insects. http://purl.obolibrary.org/obo/CL_0010000 keratinized cell of hair follicle http://purl.obolibrary.org/obo/CL_2000092 hair follicular keratinocyte A differentiating matrix keratinocyte that has initiated terminal differentiation and keratin synthesis. This cell undergoes a characteristic change while migrating upward from the hair follicle bulb, representing a committed progenitor cell destined to form the hair medulla, cortex and hair root sheath. http://purl.obolibrary.org/obo/CL_0010015 coronet cell http://purl.obolibrary.org/obo/CL_0000066 epithelial cell A highly specialized cell type exclusive to and forming neuroepithelium of the Saccus vasculosus, covering the caudal diverticulum of the infundibular recess. http://purl.obolibrary.org/obo/CL_0010016 collar cell http://purl.obolibrary.org/obo/CL_0000064 ciliated cell A cell with a flagellum surrounded by a collar of microvilli. The motion of the flagellum draws water past the microvilli, serving either a feeding or sensory function. Collar cells are found in multiple animals, including sponges, echinoderms, and cnidarians. They are also found outside animals in the choanoflagellates. Although collar cells are superficially similar, their cytoskeletal structure and functional biology are different in different groups of organisms. http://purl.obolibrary.org/obo/CL_0011007 paraxial cell http://purl.obolibrary.org/obo/CL_0000222 mesodermal cell A cell in the area of mesoderm in the neurulating embryo that flanks and forms simultaneously with the neural tube. The cells of this region give rise to somites. http://purl.obolibrary.org/obo/CL_0011008 embryonic hemocyte http://purl.obolibrary.org/obo/CL_0000387 hemocyte (sensu Arthropoda) A hemocyte derived from the embryonic head mesoderm, which enters the hemolymph as a circulating cell. http://purl.obolibrary.org/obo/CL_0011009 embryonic plasmatocyte http://purl.obolibrary.org/obo/CL_0011008 embryonic hemocyte A plasmatocyte derived from the embryonic head mesoderm. http://purl.obolibrary.org/obo/CL_0011010 lateral mesodermal cell http://purl.obolibrary.org/obo/CL_0000222 mesodermal cell A cell derived from the mesoderm that is found at the periphery of the embryo. http://purl.obolibrary.org/obo/CL_0011011 intermediate mesodermal cell http://purl.obolibrary.org/obo/CL_0000222 mesodermal cell A cell derived from the mesoderm that is located between the paraxial mesoderm and the lateral plate. http://purl.obolibrary.org/obo/CL_0011012 neural crest cell http://purl.obolibrary.org/obo/CL_0002321 embryonic cell (metazoa) A cell of the neural crest. Neural crest cells are multipotent. Premigratory neural crest cells are found at the neural plate boarder, some of which will undergo ectomesynchymal transition and delamination to form migratory neural crest cells. http://purl.obolibrary.org/obo/CL_0011114 segmented neutrophil of bone marrow http://purl.obolibrary.org/obo/CL_1001610 bone marrow hematopoietic cell A segmented neutrophilic cell of the bone marrow reserve pool that expresses CD11b (integrin alpha-M) and high levels of CD16 (low affinity immunoglobulin gamma Fc region receptor III) on its cell surface. http://purl.obolibrary.org/obo/CL_2000007 articular chondrocyte of knee joint http://purl.obolibrary.org/obo/CL_1001607 articular chondrocyte Chondrocyte forming the hyaline cartilage found in the knee joint. http://purl.obolibrary.org/obo/CL_2000008 microvascular endothelial cell http://purl.obolibrary.org/obo/CL_0000071 blood vessel endothelial cell Any blood vessel endothelial cell that is part of a microvascular endothelium. http://purl.obolibrary.org/obo/CL_2000010 dermis blood vessel endothelial cell http://purl.obolibrary.org/obo/CL_0000071 blood vessel endothelial cell Any blood vessel endothelial cell that is part of a dermis. http://purl.obolibrary.org/obo/CL_2000011 dermis lymphatic vessel endothelial cell http://purl.obolibrary.org/obo/CL_0002138 endothelial cell of lymphatic vessel Any endothelial cell of lymphatic vessel that is part of a dermis. http://purl.obolibrary.org/obo/CL_2000012 fibroblast of pedal digit skin http://purl.obolibrary.org/obo/CL_0002620 skin fibroblast Any skin fibroblast that is part of a pedal digit skin. http://purl.obolibrary.org/obo/CL_2000013 fibroblast of skin of abdomen http://purl.obolibrary.org/obo/CL_0002620 skin fibroblast Any skin fibroblast that is part of a skin of abdomen. http://purl.obolibrary.org/obo/CL_2000014 fibroblast of upper leg skin http://purl.obolibrary.org/obo/CL_0002620 skin fibroblast Any skin fibroblast that is part of a upper leg skin. http://purl.obolibrary.org/obo/CL_2000015 fibroblast of arm http://purl.obolibrary.org/obo/CL_0002620 skin fibroblast Any skin fibroblast that is part of a arm. http://purl.obolibrary.org/obo/CL_2000016 lung microvascular endothelial cell http://purl.obolibrary.org/obo/CL_2000008 microvascular endothelial cell Any lung endothelial cell that is part of a microvascular endothelium. http://purl.obolibrary.org/obo/CL_2000017 fibroblast of peridontal ligament http://purl.obolibrary.org/obo/CL_0002556 fibroblast of periodontium Any fibroblast that is part of a periodontal ligament. http://purl.obolibrary.org/obo/CL_2000018 endothelial cell of coronary artery http://purl.obolibrary.org/obo/CL_1000413 endothelial cell of artery Any endothelial cell of artery that is part of a coronary artery. http://purl.obolibrary.org/obo/CL_2000019 compound eye photoreceptor cell http://purl.obolibrary.org/obo/CL_0000287 eye photoreceptor cell Any photoreceptor cell that is part of a compound eye. http://purl.obolibrary.org/obo/CL_2000020 inner cell mass cell http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell Any native cell that is part of a inner cell mass. http://purl.obolibrary.org/obo/CL_2000021 sebaceous gland cell http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell Any native cell that is part of a sebaceous gland. http://purl.obolibrary.org/obo/CL_2000022 cardiac septum cell http://purl.obolibrary.org/obo/CL_0002494 cardiocyte Any native cell that is part of a cardiac septum. http://purl.obolibrary.org/obo/CL_2000023 spinal cord ventral column interneuron http://purl.obolibrary.org/obo/CL_0005000 spinal cord interneuron Any interneuron that is part of a spinal cord ventral column. http://purl.obolibrary.org/obo/CL_2000024 spinal cord medial motor column neuron http://purl.obolibrary.org/obo/CL_2000029 central nervous system neuron Any neuron that is part of a spinal cord medial motor column. http://purl.obolibrary.org/obo/CL_2000025 spinal cord oligodendrocyte http://purl.obolibrary.org/obo/CL_0000128 oligodendrocyte Any oligodendrocyte that is part of a spinal cord. http://purl.obolibrary.org/obo/CL_2000027 cerebellar basket cell http://purl.obolibrary.org/obo/CL_0000118 basket cell A GABAergic inhibitory interneuron located in the molecular layer of the cerebellar cortex. It projects axons that form specialized synaptic structures around Purkinje cells, including pericellular baskets, which wrap around the Purkinje cell soma, and the pinceau: a brush-like terminal that contacts the initial segment of the Purkinje cell axon. The basket cell modulates Purkinje cell activity through both chemical (GABAergic) and non-synaptic (ephaptic) mechanisms. It is arranged in sagittal rows that align with Purkinje cell zones, contributing to the cerebellum's modular and topographically organized architecture. It plays an essential role in regulating motor coordination and potentially cognitive functions. http://purl.obolibrary.org/obo/CL_2000028 cerebellum glutamatergic neuron http://purl.obolibrary.org/obo/CL_1001611 cerebellar neuron Any glutamatergic neuron that is part of a cerebellum. http://purl.obolibrary.org/obo/CL_2000029 central nervous system neuron http://purl.obolibrary.org/obo/CL_0000540 neuron Any neuron that is part of a central nervous system. http://purl.obolibrary.org/obo/CL_2000030 hypothalamus cell http://purl.obolibrary.org/obo/CL_0002319 neural cell Any native cell that is part of a hypothalamus. http://purl.obolibrary.org/obo/CL_2000031 lateral line ganglion neuron http://purl.obolibrary.org/obo/CL_2000032 peripheral nervous system neuron Any neuron that is part of a lateral line ganglion. http://purl.obolibrary.org/obo/CL_2000032 peripheral nervous system neuron http://purl.obolibrary.org/obo/CL_0000540 neuron A neuron that is part of a peripheral nervous system. http://purl.obolibrary.org/obo/CL_2000033 limb basal cell of epidermis http://purl.obolibrary.org/obo/CL_0002187 basal cell of epidermis Any basal cell of epidermis that is part of a limb. http://purl.obolibrary.org/obo/CL_2000034 anterior lateral line neuromast hair cell http://purl.obolibrary.org/obo/CL_0000856 neuromast hair cell Any neuromast hair cell that is part of a anterior lateral line. http://purl.obolibrary.org/obo/CL_2000035 anterior lateral line neuromast mantle cell http://purl.obolibrary.org/obo/CL_0000851 neuromast mantle cell Any neuromast mantle cell that is part of an anterior lateral line. http://purl.obolibrary.org/obo/CL_2000036 anterior lateral line neuromast supporting cell http://purl.obolibrary.org/obo/CL_0000852 neuromast supporting cell Any neuromast support cell that is part of a anterior lateral line. http://purl.obolibrary.org/obo/CL_2000037 posterior lateral line neuromast hair cell http://purl.obolibrary.org/obo/CL_0000856 neuromast hair cell Any neuromast hair cell that is part of a posterior lateral line. http://purl.obolibrary.org/obo/CL_2000038 posterior lateral line neuromast mantle cell http://purl.obolibrary.org/obo/CL_0000851 neuromast mantle cell Any neuromast mantle cell that is part of a posterior lateral line. http://purl.obolibrary.org/obo/CL_2000039 posterior lateral line neuromast supporting cell http://purl.obolibrary.org/obo/CL_0000852 neuromast supporting cell Any neuromast support cell that is part of a posterior lateral line. http://purl.obolibrary.org/obo/CL_2000040 bladder microvascular endothelial cell http://purl.obolibrary.org/obo/CL_2000008 microvascular endothelial cell Any microvascular endothelial cell that is part of a urinary bladder. http://purl.obolibrary.org/obo/CL_2000041 dermis microvascular lymphatic vessel endothelial cell http://purl.obolibrary.org/obo/CL_0011030 dermal microvascular endothelial cell Any dermis lymphatic vessel endothelial cell that is part of a microvascular endothelium. http://purl.obolibrary.org/obo/CL_2000042 embryonic fibroblast http://purl.obolibrary.org/obo/CL_0000057 fibroblast Any fibroblast that is part of a embryo. http://purl.obolibrary.org/obo/CL_2000043 brain pericyte http://purl.obolibrary.org/obo/CL_0002575 central nervous system pericyte Any pericyte cell that is part of a brain. http://purl.obolibrary.org/obo/CL_2000044 brain microvascular endothelial cell http://purl.obolibrary.org/obo/CL_2000008 microvascular endothelial cell Any microvascular endothelial cell that is part of a brain. http://purl.obolibrary.org/obo/CL_2000045 foreskin melanocyte http://purl.obolibrary.org/obo/CL_1000458 melanocyte of skin Any melanocyte of skin that is part of a skin of prepuce of penis. http://purl.obolibrary.org/obo/CL_2000046 ventricular cardiac muscle cell http://purl.obolibrary.org/obo/CL_0000746 cardiac muscle cell Any cardiac muscle cell that is part of a cardiac ventricle. http://purl.obolibrary.org/obo/CL_2000047 brainstem motor neuron http://purl.obolibrary.org/obo/CL_2000029 central nervous system neuron Any motor neuron that is part of a brainstem. http://purl.obolibrary.org/obo/CL_2000048 anterior horn motor neuron http://purl.obolibrary.org/obo/CL_0008039 lower motor neuron A lower motor neuron whose soma is located in the anterior horn. Anterior horn motor neurons project from the anterior portion of the grey matter in the spinal cord to some skeletal muscles. http://purl.obolibrary.org/obo/CL_2000049 primary motor cortex pyramidal cell http://purl.obolibrary.org/obo/CL_4023111 cerebral cortex pyramidal neuron Any pyramidal cell that is part of a primary motor cortex. http://purl.obolibrary.org/obo/CL_2000051 splenic fibroblast http://purl.obolibrary.org/obo/CL_0000057 fibroblast Any fibroblast that is part of a spleen. http://purl.obolibrary.org/obo/CL_2000052 umbilical artery endothelial cell http://purl.obolibrary.org/obo/CL_1000413 endothelial cell of artery Any endothelial cell of artery that is part of a umbilical cord. http://purl.obolibrary.org/obo/CL_2000053 splenic endothelial cell http://purl.obolibrary.org/obo/CL_0000115 endothelial cell Any endothelial cell that is part of a spleen. http://purl.obolibrary.org/obo/CL_2000054 hepatic pit cell http://purl.obolibrary.org/obo/CL_4047101 liver-resident natural killer cell A large, granular, liver specific natural killer cell that adheres to the endothelial cells of the hepatic sinusoid. http://purl.obolibrary.org/obo/CL_2000055 liver dendritic cell http://purl.obolibrary.org/obo/CL_0000451 dendritic cell Any dendritic cell that is part of a liver. http://purl.obolibrary.org/obo/CL_2000056 Meynert cell http://purl.obolibrary.org/obo/CL_2000049 primary motor cortex pyramidal cell Any pyramidal cell that is part of a regional part of cerebral cortex. http://purl.obolibrary.org/obo/CL_2000057 femoral osteoblast http://purl.obolibrary.org/obo/CL_0001035 bone cell Any osteoblast that is part of a femur. http://purl.obolibrary.org/obo/CL_2000058 calvarial osteoblast http://purl.obolibrary.org/obo/CL_0000062 osteoblast Any osteoblast that is part of a skull. http://purl.obolibrary.org/obo/CL_2000059 prostate gland microvascular endothelial cell http://purl.obolibrary.org/obo/CL_2000008 microvascular endothelial cell Any microvascular endothelial cell that is part of a prostate gland. http://purl.obolibrary.org/obo/CL_2000060 placental villous trophoblast http://purl.obolibrary.org/obo/CL_0000351 trophoblast cell A trophoblast of placental villi. These cells fuse to form synctial trophoplast - the placental side of the interface between the placenta and maternal blood sinusoids in the decidua. http://purl.obolibrary.org/obo/CL_2000061 placental amniotic mesenchymal stromal cell http://purl.obolibrary.org/obo/CL_0000134 mesenchymal stem cell Any mesenchymal stem cell that is part of a placenta. http://purl.obolibrary.org/obo/CL_2000062 placental villus capillary endothelial cell http://purl.obolibrary.org/obo/CL_0009092 endothelial cell of placenta Any capillary endothelial cell that is part of a placenta. http://purl.obolibrary.org/obo/CL_2000063 ovarian fibroblast http://purl.obolibrary.org/obo/CL_0002132 stromal cell of ovary Any fibroblast that is part of a female gonad. http://purl.obolibrary.org/obo/CL_2000064 ovarian surface epithelial cell http://purl.obolibrary.org/obo/CL_0002078 meso-epithelial cell A meso-epithelial cell of the ovarian surface epithelium, varying in shape from flat to cuboidal to pseudostratified columnar. This cell plays a crucial role in ovulation by producing proteolytic enzymes in response to gonadotropins, facilitating follicle rupture through tissue breakdown and TNF-alpha signaling. Additionally, this cell contributes to post-ovulatory wound repair (Morris et al., 2022) and exhibits stem cell-like properties (Flesken-Nikitin et al., 2013; Wang et al., 2019). http://purl.obolibrary.org/obo/CL_2000065 ovarian microvascular endothelial cell http://purl.obolibrary.org/obo/CL_2000008 microvascular endothelial cell Any microvascular endothelial cell that is part of a female urethra. http://purl.obolibrary.org/obo/CL_2000066 cardiac ventricle fibroblast http://purl.obolibrary.org/obo/CL_0002548 fibroblast of cardiac tissue Any fibroblast that is part of a cardiac ventricle. http://purl.obolibrary.org/obo/CL_2000067 cardiac atrium fibroblast http://purl.obolibrary.org/obo/CL_0002548 fibroblast of cardiac tissue Any fibroblast that is part of a cardiac atrium. http://purl.obolibrary.org/obo/CL_2000068 pericardium fibroblast http://purl.obolibrary.org/obo/CL_0000057 fibroblast Any fibroblast that is part of a pericardium. http://purl.obolibrary.org/obo/CL_2000069 gallbladder fibroblast http://purl.obolibrary.org/obo/CL_0000057 fibroblast Any fibroblast that is part of a gallbladder. http://purl.obolibrary.org/obo/CL_2000070 optic choroid fibroblast http://purl.obolibrary.org/obo/CL_0000348 choroidal cell of the eye Any fibroblast that is part of a optic choroid. http://purl.obolibrary.org/obo/CL_2000071 mammary microvascular endothelial cell http://purl.obolibrary.org/obo/CL_2000008 microvascular endothelial cell Any microvascular endothelial cell that is part of a breast. http://purl.obolibrary.org/obo/CL_2000072 adipose microvascular endothelial cell http://purl.obolibrary.org/obo/CL_2000008 microvascular endothelial cell Any microvascular endothelial cell that is part of a adipose tissue. http://purl.obolibrary.org/obo/CL_2000073 migratory cardiac neural crest cell http://purl.obolibrary.org/obo/CL_0000333 migratory neural crest cell Any migratory neural crest cell that is part of a cardiac neural crest. http://purl.obolibrary.org/obo/CL_2000074 splenocyte http://purl.obolibrary.org/obo/CL_0000738 leukocyte Any leukocyte that is part of a spleen. http://purl.obolibrary.org/obo/CL_2000075 anterior visceral endoderm cell http://purl.obolibrary.org/obo/CL_0000223 endodermal cell Any endodermal cell that is part of a anterior visceral endoderm. http://purl.obolibrary.org/obo/CL_2000076 hindlimb stylopod vein endothelial cell http://purl.obolibrary.org/obo/CL_0002543 vein endothelial cell Any vein endothelial cell that is part of a hindlimb stylopod. http://purl.obolibrary.org/obo/CL_2000077 skeletal muscle tissue of pectoralis major striated muscle cell http://purl.obolibrary.org/obo/CL_0000737 striated muscle cell Any striated muscle cell that is part of a skeletal muscle tissue of pectoralis major. http://purl.obolibrary.org/obo/CL_2000078 placental pericyte http://purl.obolibrary.org/obo/CL_0000669 pericyte Any pericyte cell that is part of a placenta. http://purl.obolibrary.org/obo/CL_2000079 mesenchymal stem cell of femoral bone marrow http://purl.obolibrary.org/obo/CL_0002540 mesenchymal stem cell of the bone marrow Any mesenchymal stem cell of the bone marrow that is part of a femur. http://purl.obolibrary.org/obo/CL_2000080 mesenchymal stem cell of abdominal adipose tissue http://purl.obolibrary.org/obo/CL_0002570 mesenchymal stem cell of adipose tissue Any mesenchymal stem cell of adipose tissue that is part of an abdomen. http://purl.obolibrary.org/obo/CL_2000081 melanocyte of skin of face http://purl.obolibrary.org/obo/CL_1000458 melanocyte of skin Any melanocyte of skin that is part of a skin of face. http://purl.obolibrary.org/obo/CL_2000083 hair follicle dermal papilla cell of scalp http://purl.obolibrary.org/obo/CL_0000346 hair follicle dermal papilla cell Any hair follicle dermal papilla cell that is part of a scalp. http://purl.obolibrary.org/obo/CL_2000084 conjunctiva goblet cell http://purl.obolibrary.org/obo/CL_1000432 conjunctival epithelial cell A goblet cell that is part of the conjunctival epithelium, characterized by apical accumulation of mucin granules (containing MUC5AC in humans; Muc5ac/Muc5b in mice). These gel-forming mucins support tear film stability, ocular lubrication, and pathogen defence. The conjunctival goblet cell forms tight junctions with neighbouring epithelial cells via species-specific claudins (claudin-10 in humans, claudin-2 in mice) and regulates immune homeostasis by facilitating soluble antigen transport to dendritic cells through goblet cell-associated antigen passages (GAPs) (Barbosa et al., 2017). The transcription factor SPDEF is essential for its differentiation. http://purl.obolibrary.org/obo/CL_2000085 mononuclear cell of umbilical cord http://purl.obolibrary.org/obo/CL_0000842 mononuclear leukocyte Any mononuclear cell that is part of a umbilical cord. http://purl.obolibrary.org/obo/CL_2000086 neocortex basket cell http://purl.obolibrary.org/obo/CL_0010011 cerebral cortex GABAergic interneuron Any basket cell that is part of a neocortex. http://purl.obolibrary.org/obo/CL_2000087 dentate gyrus of hippocampal formation basket cell http://purl.obolibrary.org/obo/CL_4023062 dentate gyrus neuron Any basket cell that is part of a dentate gyrus of hippocampal formation. http://purl.obolibrary.org/obo/CL_2000088 Ammon's horn basket cell http://purl.obolibrary.org/obo/CL_1001569 hippocampal interneuron Any basket cell that is part of a Ammon's horn. http://purl.obolibrary.org/obo/CL_2000089 dentate gyrus granule cell http://purl.obolibrary.org/obo/CL_4023062 dentate gyrus neuron A granule cell that has soma location in the dentate gyrus cell layer of the hippocampal formation and has an elliptical cell body and characteristic cone-shaped tree of spiny apical dendrites. The branches extend throughout the molecular layer and the distal tips of the dendritic tree end just at the hippocampal fissure or at the ventricular surface. The dentate gyrus granule cell is the principal cell type of the dentate gyrus. http://purl.obolibrary.org/obo/CL_2000090 dentate gyrus of hippocampal formation stellate cell http://purl.obolibrary.org/obo/CL_4023062 dentate gyrus neuron Any stellate cell that is part of a dentate gyrus of hippocampal formation. http://purl.obolibrary.org/obo/CL_2000091 endometrial microvascular endothelial cell http://purl.obolibrary.org/obo/CL_0009095 endothelial cell of uterus Any microvascular endothelial cell that is part of a endometrial blood vessel. http://purl.obolibrary.org/obo/CL_2000092 hair follicular keratinocyte http://purl.obolibrary.org/obo/CL_4052061 epidermal keratinocyte Any keratinocyte that is part of a hair follicle. http://purl.obolibrary.org/obo/CL_2000093 bronchus fibroblast of lung http://purl.obolibrary.org/obo/CL_0002553 fibroblast of lung Any fibroblast of lung that is part of a bronchus. http://purl.obolibrary.org/obo/CL_2000094 nasal cavity respiratory epithelium epithelial cell of viscerocranial mucosa http://purl.obolibrary.org/obo/CL_1000441 epithelial cell of viscerocranial mucosa Any epithelial cell of viscerocranial mucosa that is part of a nasal cavity respiratory epithelium. http://purl.obolibrary.org/obo/CL_2000095 cord blood hematopoietic stem cell http://purl.obolibrary.org/obo/CL_0002352 gestational hematopoietic stem cell Any hematopoietic stem cell that is part of a umbilical cord blood. http://purl.obolibrary.org/obo/CL_2000096 fibroblast of the reticular layer of dermis http://purl.obolibrary.org/obo/CL_0002551 fibroblast of dermis A fibroblast of dermis that resides in the deep reticular layer, characterised by robust extracellular matrix production with high type I collagen deposition forming densely packed, organised fibrillar networks (Ghetti et al., 2018). This cell exhibits pro-fibrotic properties during wound healing, entering wounds early where it proliferates and deposits collagen to restore dermal architecture (Knoedler et al., 2023; McAndrews et al., 2022). It is distinguished from papillary dermal fibroblasts by expression of COL11A1, POSTN, and SPP1 in humans (Wu et al., 2022). http://purl.obolibrary.org/obo/CL_2000097 midbrain dopaminergic neuron http://purl.obolibrary.org/obo/CL_2000029 central nervous system neuron Any dopaminergic neuron that is part of a midbrain. http://purl.obolibrary.org/obo/UBERON_0034978 paraganglion (generic) http://purl.obolibrary.org/obo/UBERON_0010313 neural crest-derived structure A cluster of neuroendocrine cells derived from neural crest. Paraganglia may be chromaffin or nonchromaffin. http://purl.obolibrary.org/obo/UBERON_0034995 jaw mesenchyme http://purl.obolibrary.org/obo/UBERON_0003104 mesenchyme Mesenchyme that is part of a developing jaw [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0035034 eyelid epithelium http://purl.obolibrary.org/obo/UBERON_0015808 eye epithelium An epithelium that is part of an eyelid [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0035049 excretory duct of salivary gland http://purl.obolibrary.org/obo/UBERON_0035050 excretory duct Any of the interlobular excretory ducts of a salivary gland which are found in the connective tissue septa and formed by the union of several intralobular striated (secretory) ducts[MP,generalized]. http://purl.obolibrary.org/obo/UBERON_0035073 duct of eccrine sweat gland http://purl.obolibrary.org/obo/UBERON_0000058 duct A duct made up of simple tubular epithelium that is part of an eccrine sweat gland. The main function of the duct of the eccrine sweat gland is the reabsorption of Na and Cl ions as sweat flows through the duct. It has two cell layers: basal and luminal. It is continuous with the secretory coil and goes towards the skin surface. The distal segment of the duct is relatively straight and connects with the acrosyringium in the epidermis. Most of the ion reabsorption occurs in the proximal part of the duct. http://purl.obolibrary.org/obo/UBERON_0035267 neck of gallbladder http://purl.obolibrary.org/obo/UBERON_0001560 neck of organ The narrowest portion of the gallbladder and distal to the cystic duct. http://purl.obolibrary.org/obo/UBERON_0035316 prostatic capsule http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure The membrane the surrounds the prostate gland. http://purl.obolibrary.org/obo/UBERON_0035553 left cardiac chamber http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure Any chamber of the left side of the heart. http://purl.obolibrary.org/obo/UBERON_0035554 right cardiac chamber http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure Any chamber of the right side of the heart. http://purl.obolibrary.org/obo/UBERON_0035639 ocular adnexa http://purl.obolibrary.org/obo/UBERON_0034921 multi organ part structure The parts of the orbital region that are outside of the the eyeball, including the lacrimal apparatus, the extraocular muscles and the eyelids, eyelashes, eyebrows and the conjunctiva. http://purl.obolibrary.org/obo/UBERON_0035804 future mouth http://purl.obolibrary.org/obo/UBERON_0013522 subdivision of tube The primordial mouth region of the developing head. http://purl.obolibrary.org/obo/UBERON_0035805 muscle layer of sigmoid colon http://purl.obolibrary.org/obo/UBERON_0012489 muscle layer of colon A muscle layer that is part of the sigmoid colon. http://purl.obolibrary.org/obo/UBERON_0035820 peritoneal sac http://purl.obolibrary.org/obo/UBERON_0005906 serous sac A serous sac that is the aggregate of the peritoneum and the peritoneal cavity, located in the abdominal cavity. http://purl.obolibrary.org/obo/GO_1905952 regulation of lipid localization http://purl.obolibrary.org/obo/GO_0032879 regulation of localization Any process that modulates the frequency, rate or extent of lipid localization. http://purl.obolibrary.org/obo/GO_1905953 negative regulation of lipid localization http://purl.obolibrary.org/obo/GO_1905952 regulation of lipid localization Any process that stops, prevents or reduces the frequency, rate or extent of lipid localization. http://purl.obolibrary.org/obo/GO_1905954 positive regulation of lipid localization http://purl.obolibrary.org/obo/GO_1905952 regulation of lipid localization Any process that activates or increases the frequency, rate or extent of lipid localization. http://purl.obolibrary.org/obo/GO_1905957 regulation of cellular response to alcohol http://purl.obolibrary.org/obo/GO_1901419 regulation of response to alcohol Any process that modulates the frequency, rate or extent of cellular response to alcohol. http://purl.obolibrary.org/obo/GO_1905958 negative regulation of cellular response to alcohol http://purl.obolibrary.org/obo/GO_1905957 regulation of cellular response to alcohol Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to alcohol. http://purl.obolibrary.org/obo/GO_1905959 positive regulation of cellular response to alcohol http://purl.obolibrary.org/obo/GO_1905957 regulation of cellular response to alcohol Any process that activates or increases the frequency, rate or extent of cellular response to alcohol. http://purl.obolibrary.org/obo/GO_0140053 mitochondrial gene expression http://purl.obolibrary.org/obo/GO_0010467 gene expression The process in which a mitochondrial gene's sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form. http://purl.obolibrary.org/obo/GO_0106027 neuron projection organization http://purl.obolibrary.org/obo/GO_0120036 plasma membrane bounded cell projection organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a neuron, e.g. an axon, or a dendrite. http://purl.obolibrary.org/obo/GO_0110021 cardiac muscle myoblast proliferation http://purl.obolibrary.org/obo/GO_0051450 myoblast proliferation The multiplication or reproduction of cardiac muscle myoblasts, resulting in the expansion of a cardiac muscle myoblast cell population. A cardiac myoblast is a precursor cell that has been committed to a cardiac muscle cell fate but retains the ability to divide and proliferate throughout life. http://purl.obolibrary.org/obo/GO_0110022 regulation of cardiac muscle myoblast proliferation http://purl.obolibrary.org/obo/GO_2000291 regulation of myoblast proliferation Any process that modulates the frequency, rate or extent of cardiac muscle myoblast proliferation. http://purl.obolibrary.org/obo/GO_0110023 negative regulation of cardiac muscle myoblast proliferation http://purl.obolibrary.org/obo/GO_0110022 regulation of cardiac muscle myoblast proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle myoblast proliferation. http://purl.obolibrary.org/obo/GO_0110024 positive regulation of cardiac muscle myoblast proliferation http://purl.obolibrary.org/obo/GO_0110022 regulation of cardiac muscle myoblast proliferation Any process that activates or increases the frequency, rate or extent of cardiac muscle myoblast proliferation. http://purl.obolibrary.org/obo/UBERON_0036224 corticobulbar and corticospinal tracts http://purl.obolibrary.org/obo/UBERON_0001018 axon tract The corticobulbar and corticospinal tracts combined. http://purl.obolibrary.org/obo/UBERON_0036225 respiratory system gland http://purl.obolibrary.org/obo/UBERON_0002530 gland Any gland that is part os the respiratory system. http://purl.obolibrary.org/obo/GO_0099160 postsynaptic intermediate filament cytoskeleton http://purl.obolibrary.org/obo/GO_0099571 postsynaptic cytoskeleton The intermediate filament cytoskeleton that is part of a postsynapse. http://purl.obolibrary.org/obo/UBERON_0036245 parenchyma of mammary gland http://purl.obolibrary.org/obo/UBERON_0000353 parenchyma Parenchymal tissue that consists of the alveoli, grape-like clusters where milk is stored, and branching ducts, which are tubular canals carrying gladular secretions. http://purl.obolibrary.org/obo/UBERON_0036248 joint of auditory ossicle http://purl.obolibrary.org/obo/UBERON_0002217 synovial joint Any synovial joint that connects auditory ossicles. http://purl.obolibrary.org/obo/GO_0120111 neuron projection cytoplasm http://purl.obolibrary.org/obo/GO_0005737 cytoplasm All of the contents of a plasma membrane bounded neuron projection, excluding the plasma membrane surrounding the projection. http://purl.obolibrary.org/obo/GO_0110067 ammonium transmembrane transporter complex http://purl.obolibrary.org/obo/GO_1902495 transmembrane transporter complex High affinity ammonium transporter complex that enables the transfer of ammonium from one side of a membrane to the other. http://purl.obolibrary.org/obo/PATO_0045050 normal size http://purl.obolibrary.org/obo/PATO_0045001 normal object quality A size quality which is relatively normal or average http://purl.obolibrary.org/obo/GO_0061971 replacement bone morphogenesis http://purl.obolibrary.org/obo/GO_0060349 bone morphogenesis The process in which bones are generated and organized as a result of the conversion of another structural tissue into bone. http://purl.obolibrary.org/obo/GO_0061972 dermal bone morphogenesis http://purl.obolibrary.org/obo/GO_0061973 membrane bone morphogenesis The process in which bone which forms superficially in the organism are generated and organized. http://purl.obolibrary.org/obo/GO_0061973 membrane bone morphogenesis http://purl.obolibrary.org/obo/GO_0060349 bone morphogenesis The process in which bone which forms deep in the organism are generated and organized. http://purl.obolibrary.org/obo/GO_0062137 cargo receptor complex http://purl.obolibrary.org/obo/GO_0098796 membrane protein complex Any protein complex that is part of a membrane and which functions as a cargo receptor. http://purl.obolibrary.org/obo/GO_0140513 nuclear protein-containing complex http://purl.obolibrary.org/obo/GO_0032991 protein-containing complex A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together in the nucleus. http://purl.obolibrary.org/obo/GO_0140546 defense response to symbiont http://purl.obolibrary.org/obo/GO_0098542 defense response to other organism Reactions triggered in response to the presence of a symbiont that act to protect or prevent damage to the host. http://purl.obolibrary.org/obo/UBERON_8400006 liver lobule periportal region http://purl.obolibrary.org/obo/UBERON_8400005 metabolic zone of liver The region of the liver lobule that is closest to the portal triad. The functionally-defined hepatic acinus zone 1 is generally found in this region. http://purl.obolibrary.org/obo/UBERON_8400007 liver lobule centrilobular region http://purl.obolibrary.org/obo/UBERON_8400005 metabolic zone of liver The region of the liver lobule that is closest to the central vein. The functionally-defined hepatic acinus zone 3 is generally found in this region. http://purl.obolibrary.org/obo/UBERON_8400008 liver lobule midzonal region http://purl.obolibrary.org/obo/UBERON_8400005 metabolic zone of liver The region of the liver lobule that is between the periportal and centrilobular regions. The functionally-defined hepatic acinus zone 2 is generally found in this region. http://purl.obolibrary.org/obo/CL_0009007 gastrointestinal tract (lamina propria) macrophage of small intestine http://purl.obolibrary.org/obo/CL_0000865 gastrointestinal tract (lamina propria) macrophage A macrophage which is resident in the lamina propria of the small intestine. http://purl.obolibrary.org/obo/CL_0009008 gastrointestinal tract (lamina propria) macrophage of large intestine http://purl.obolibrary.org/obo/CL_0000865 gastrointestinal tract (lamina propria) macrophage A macrophage which is resident in the lamina propria of the large intestine. http://purl.obolibrary.org/obo/CL_0009021 stromal cell of lamina propria of large intestine http://purl.obolibrary.org/obo/CL_0000499 stromal cell A stromal cell found in the lamina propria of the large intestine. http://purl.obolibrary.org/obo/CL_0009022 stromal cell of lamina propria of small intestine http://purl.obolibrary.org/obo/CL_0000499 stromal cell A stromal cell found in the lamina propria of the small intestine. http://purl.obolibrary.org/obo/CL_0009023 small intestine Peyer's patch T cell http://purl.obolibrary.org/obo/CL_0009014 Peyer's patch lymphocyte A T cell which resides in the Peyer's patch of the small intestine. http://purl.obolibrary.org/obo/CL_0009024 mesothelial cell of small intestine http://purl.obolibrary.org/obo/CL_0008041 mesothelial cell of intestine A mesothelial cell that is part of the small intestine. http://purl.obolibrary.org/obo/CL_0009025 mesothelial cell of colon http://purl.obolibrary.org/obo/CL_0008041 mesothelial cell of intestine A mesothelial cell that is part of the colon. http://purl.obolibrary.org/obo/CL_4023007 L2/3 bipolar VIP GABAergic interneuron (Mmus) http://purl.obolibrary.org/obo/CL_4023016 VIP GABAergic interneuron A VIP GABAergic cortical interneuron with bipolar morphology, with a soma found in L2/3. L2/3 bipolar VIP cells have extending axons across all layers (with preferences for layers II/III and Va) and a dendritic tree that is vertically more restricted than deeper layer VIP cells and extend fewer dendrites into the layers outside their home layer (location of soma). L2/3 bipolar VIP cells have great variability in firing patterns, though most are continuous adapting. L2/3 bipolar VIP cells are more depolarized in their resting state, had less fast rectification, and had smaller after hyperpolarization than deeper VIP cells. http://purl.obolibrary.org/obo/CL_4023008 intratelencephalic-projecting glutamatergic cortical neuron http://purl.obolibrary.org/obo/CL_0010012 cerebral cortex neuron A glutamatergic neuron located in the cerebral cortex that projects to structures of telencephalic origins. http://purl.obolibrary.org/obo/CL_4023009 extratelencephalic-projecting glutamatergic cortical neuron http://purl.obolibrary.org/obo/CL_0010012 cerebral cortex neuron A glutamatergic neuron located in the cerebral cortex that projects to structures not derived from telencephalon. http://purl.obolibrary.org/obo/CL_4023012 near-projecting glutamatergic cortical neuron http://purl.obolibrary.org/obo/CL_0010012 cerebral cortex neuron A glutamatergic neuron located in the cerebral cortex that projects axons locally rather than distantly. http://purl.obolibrary.org/obo/CL_4023013 corticothalamic-projecting glutamatergic cortical neuron http://purl.obolibrary.org/obo/CL_0010012 cerebral cortex neuron A glutamatergic neuron located in the cerebral cortex that projects to the thalamus. http://purl.obolibrary.org/obo/CL_4023014 L5 VIP GABAergic interneuron (Mmus) http://purl.obolibrary.org/obo/CL_4023016 VIP GABAergic interneuron A VIP GABAergic cortical interneuron with a soma found in L5. L5 VIP cells have mostly local morphology with some deep-projecting axons. They show only moderate resistance, comparable to that of sst subclass and unlike typical VIP subclass cells that tend to show high input resistance. L5 VIP cells show particularly low resting membrane potential. http://purl.obolibrary.org/obo/CL_4023019 L5/6 cck, VIP GABAergic interneuron (Mmus) http://purl.obolibrary.org/obo/CL_4023071 L5/6 cck GABAergic interneuron (Mmus) A VIP GABAergic cortical interneuron that expresses cck. L5/6 cck cells have soma found mainly in L5 and L6 and have large axonal arborization. http://purl.obolibrary.org/obo/CL_4023022 canopy lamp5 GABAergic cortical interneuron (Mmus) http://purl.obolibrary.org/obo/CL_4023011 lamp5 GABAergic interneuron A Lamp5 GABAergic cortical interneuron that has extended axons in the surface of L1. Canopy Lamp5 cells resemble neurogliaform cells in having elongated horizontal axonal arbors largely confined to L1; but the dendritic arbors are wider and have fewer branches, while the axon is less tortuous and extends further from the soma http://purl.obolibrary.org/obo/CL_4023023 L5,6 neurogliaform lamp5 GABAergic interneuron (Mmus) http://purl.obolibrary.org/obo/CL_4023011 lamp5 GABAergic interneuron A lamp 5 GABAergic cortical interneuron with neurogliaform morphology with a soma found in L5,6. L5,6 NGC lamp5 have deep afterhyperpolarization (AHP) but narrow action potentials (APs). Unlike other deep neurogliaform cells (which are caudal ganglionic eminence (CGE) derived), L5,6 NGC lamp5 cells are medial ganglionic eminence (MGE)-derived http://purl.obolibrary.org/obo/CL_4023024 neurogliaform lamp5 GABAergic cortical interneuron (Mmus) http://purl.obolibrary.org/obo/CL_4023011 lamp5 GABAergic interneuron A lamp5 GABAergic cortical interneuron with layer-adapting morphology. NGC lamp5 cells have a small round soma, short dendrites, and a wide dense axonal arbor that tends to establish a dense axonal mesh with high connection probability both to themselves and L2 pyramidal cells. NGC lamp5 cells have unique synaptic properties that distinguish them from other GABAergic interneurons, including the release of GABA to the extracellular space via volume transmission, and the ability to produce GABA-B responses in connected postsynaptic targets. http://purl.obolibrary.org/obo/CL_4023025 long-range projecting sst GABAergic cortical interneuron (Mmus) http://purl.obolibrary.org/obo/CL_4023121 sst chodl GABAergic interneuron A sst GABAergic cortical interneuron that is both an interneuron and a projecting neuron. They are found in all layers from upper L2/3 down to the bottom of L6. They have long-range projections, some with axons fading into white matter. These cells have low rebound potential, low hyperpolarization sag, and high variability in membrane time constant. http://purl.obolibrary.org/obo/CL_4023027 L5 sst T-Martinotti interneuron (Mmus) http://purl.obolibrary.org/obo/CL_4023086 T Martinotti neuron A sst GABAergic cortical interneuron with a soma found in L5 and possesses 'T-shaped' Martinotti morphologies with local axonal plexus in L5a and translaminar axons restricted to the uppermost part of L1. They show low-threshold spiking patterns with strong rebound firing, and inhibit the L1 apical tuft of nearby pyramidal cells. http://purl.obolibrary.org/obo/CL_4023028 L5 non-Martinotti sst GABAergic interneuron (Mmus) http://purl.obolibrary.org/obo/CL_0010011 cerebral cortex GABAergic interneuron A sst GABAergic cortical interneuron with a soma found in lower L5 with mostly local axonal arborization but with some sparse ascending axons. L5 non-Martinotti sst cells show somatic localization and local axon plexus in L5b and L5b/6 and substantial innervation of L3 and L4, and receive thalamic input from the ventral posteromedial nucleus and specifically target L4 neurons, avoiding L5 pyramidal cells. L5 non-Martinotti sst cells tend to show a higher input resistance and seem to be less stuttering. http://purl.obolibrary.org/obo/CL_4023030 L2/3/5 fan Martinotti sst GABAergic interneuron (Mmus) http://purl.obolibrary.org/obo/CL_0010011 cerebral cortex GABAergic interneuron A sst GABAergic cortical interneuron that has "fanning-out' Martinotti morphology that is found in layer 2/3/5 of the cerebral cortex. They have local axon arbor and long ascending axons that spreads horizontally and arborizes significantly in L1. http://purl.obolibrary.org/obo/CL_4023031 L4 sst Martinotti interneuron (Mmus) http://purl.obolibrary.org/obo/CL_4023076 Martinotti neuron A sst GABAergic cortical interneuron with a soma found in lower L2/3 and upper 5, L4 Sst cells have Martinotti morphology with ascending axons but denser local axons and sparser ‘fanning-out’ projections to L1. L4 sst cells have smaller membrane time constant to calb2 (L2/3/5 fan Martinotti Cell) and non-zero afterdepolarization (ADP). http://purl.obolibrary.org/obo/CL_4023036 pvalb chandelier GABAergic interneuron http://purl.obolibrary.org/obo/CL_4023069 medial ganglionic eminence derived GABAergic interneuron A transcriptomically distinct pvalb GABAergic interneuron located in the pallium. It is recognizable by the straight terminal axonal 'cartridges' of vertically oriented strings of synaptic boutons. Chandelier PV cells' boutons target exclusively the axon initial segment (AIS) of pyramidal cells, with a single cell innervating hundreds of pyramidal cells in a clustered manner. These cells are fast-spiking. http://purl.obolibrary.org/obo/CL_4023069 medial ganglionic eminence derived GABAergic interneuron http://purl.obolibrary.org/obo/CL_4023063 medial ganglionic eminence derived interneuron A GABAergic interneuron that develops from the medial ganglionic eminence and has migrated to the cerebral cortex. http://purl.obolibrary.org/obo/CL_0009035 stromal cell of lamina propria of vermiform appendix http://purl.obolibrary.org/obo/CL_0009021 stromal cell of lamina propria of large intestine A stromal cell found in the lamina propria of the vermiform appendix. http://purl.obolibrary.org/obo/CL_0017506 banded nucleus http://purl.obolibrary.org/obo/GO_0005634 nucleus A concave nuclear shape where the nucleus is indented to more than half the distance to the farthest nuclear margin, but in no area is the chromatin condensed to a single filament. http://purl.obolibrary.org/obo/CL_0017508 cartwheel heterochromatin http://purl.obolibrary.org/obo/GO_0000792 heterochromatin Heterochromatin that is arranged in a carthwheel pattern. http://purl.obolibrary.org/obo/CL_4023075 L6 th sst GABAergic interneuron (Mmus) http://purl.obolibrary.org/obo/CL_0010011 cerebral cortex GABAergic interneuron A sst GABAergic cortical interneuron found in L6 that expresses tyrosine hydroxylase. L6 Th+ SST cells have mostly local axonal arborization within L6. http://purl.obolibrary.org/obo/CL_4023121 sst chodl GABAergic interneuron http://purl.obolibrary.org/obo/CL_4023017 sst GABAergic interneuron A transcriptomically distinct sst GABAergic interneuron that also expresses Chodl. These neurons are rare and correspond to the only known interneurons with long-range projection. http://purl.obolibrary.org/obo/CL_0009100 hepatic portal fibroblast http://purl.obolibrary.org/obo/CL_0000057 fibroblast A fibroblast located in the portal triad. Hepatic portal fibroblast are a non-parenchymal cell population located adjacent to bile duct epithelia in liver and are distinct from stellate cells. They differentiate into fibrogenic myofibroblasts during chronic injury states producing high levels of collagen. http://purl.obolibrary.org/obo/UBERON_8410081 blood microvessel http://purl.obolibrary.org/obo/UBERON_0010523 microcirculatory vessel Any of the smallest blood vessels where blood circulates within organ tissues. Microvessels include terminal arterioles, metarterioles, capillaries, and venules (but exclude lymphatic capillaries). Arterioles carry oxygenated blood to the capillaries, and blood flows out of the capillaries through venules into veins. http://purl.obolibrary.org/obo/GO_0120331 endothelial tube formation http://purl.obolibrary.org/obo/GO_0072175 epithelial tube formation The developmental process pertaining to the initial formation of an endothelial tube. http://purl.obolibrary.org/obo/CL_4023168 somatosensory neuron http://purl.obolibrary.org/obo/CL_2000032 peripheral nervous system neuron A neuron that is part of the somatic sensory system. Somatosensory neurons innervate the skin or integument to detect different types of thermal, chemical, and mechanical touch stimuli. http://purl.obolibrary.org/obo/CL_4023169 trigeminal neuron http://purl.obolibrary.org/obo/CL_2000029 central nervous system neuron A neuron that is responsible for sensation in the face or motor functions such as biting and chewing. Trigeminal neurons extend a single axon shaft along the lateral white matter of the hindbrain and spinal cord. The highly branched axons innervate the integument of the head. http://purl.obolibrary.org/obo/CL_0017006 B-lymphoblast http://purl.obolibrary.org/obo/CL_0017005 lymphoblast A lymphocyte of B lineage that has gotten larger after being stimulated by an antigen. http://purl.obolibrary.org/obo/CL_0004117 alpha retinal ganglion cell (Mmus) http://purl.obolibrary.org/obo/CL_0000740 retinal ganglion cell A large-bodied retinal projection neuron with wide monostratified dendritic arbors in defined IPL strata, high neurofilament and osteopontin expression, and a thick, fast-conducting axon. It shows short-latency, non-direction-selective responses with large receptive fields and a distinctive rapid action potential waveform. In mammals it forms about five percent of RGCs and includes four conserved ON and OFF sustained and transient subtypes. http://purl.obolibrary.org/obo/CL_0004253 wide field retinal amacrine cell http://purl.obolibrary.org/obo/CL_0000561 amacrine cell An amicrine that has a wide dendritic field. http://purl.obolibrary.org/obo/CL_0004227 flat bistratified amacrine cell http://purl.obolibrary.org/obo/CL_4030028 glycinergic amacrine cell A bistratified amacrine cell with a small dendritic field. Flat bistratified amacrine cells have post-synaptic terminals both on the border of S1 and S2, and on the border of S3 and S4. This cell type releases the neurotransmitter glycine. http://purl.obolibrary.org/obo/CL_0003011 G8 retinal ganglion cell http://purl.obolibrary.org/obo/CL_0000740 retinal ganglion cell A mono-stratified retinal ganglion cell that has a large dendritic field and a sparse dendritic arbor with post synaptic terminals in sublaminar layer S4. http://purl.obolibrary.org/obo/CL_0004120 retinal ganglion cell A1 http://purl.obolibrary.org/obo/CL_0004117 alpha retinal ganglion cell (Mmus) A retinal ganglion A cell found in the retina with large somata, often polygonal in shape. The dendritic fields consist of three to seven stout dendrites that are sparce near soma. Dendrites terminate in S4. http://purl.obolibrary.org/obo/CL_0004119 retinal ganglion cell B1 http://purl.obolibrary.org/obo/CL_0004115 retinal ganglion cell B A retinal ganglion cell B that has medium body size, medium dendritic field and dense dendritic arbor, and has post synaptic terminals in S2. http://purl.obolibrary.org/obo/CL_0004244 WF4 amacrine cell http://purl.obolibrary.org/obo/CL_0004253 wide field retinal amacrine cell An amacrine cell with a wide dendritic field, dendrites in S4, and post-synaptic terminals in S4. http://purl.obolibrary.org/obo/CL_0003016 G11-OFF retinal ganglion cell http://purl.obolibrary.org/obo/CL_0003014 G11 retinal ganglion cell A G11 retinal ganglion cell that has post synaptic terminals in sublaminar layer S2 and is depolarized by decreased illumination of their receptive field center http://purl.obolibrary.org/obo/CL_0004121 retinal ganglion cell B2 http://purl.obolibrary.org/obo/CL_0004115 retinal ganglion cell B A retinal ganglion cell B that has a very small but very dense dendritic field, and has post synaptic terminals in S2. http://purl.obolibrary.org/obo/CL_0004214 type 3b cone bipolar cell http://purl.obolibrary.org/obo/CL_0000755 type 3 cone bipolar cell (sensu Mus) A type of type 3 cone bipolar cell with distinctive crescent-shaped dendrites. http://purl.obolibrary.org/obo/CL_4023061 hippocampal CA4 neuron http://purl.obolibrary.org/obo/CL_2000029 central nervous system neuron A neuron that has its soma located in CA4 of the hippocampus. http://purl.obolibrary.org/obo/CL_4023079 midbrain-derived inhibitory neuron http://purl.obolibrary.org/obo/CL_2000029 central nervous system neuron A GABAergic inhibitory neuron that is derived from the midbrain. http://purl.obolibrary.org/obo/CL_4023188 midget ganglion cell of retina http://purl.obolibrary.org/obo/CL_0000740 retinal ganglion cell A retinal ganglion cell that originate in the ganglion cell layer of the retina, and project to the parvocellular layers of the lateral geniculate nucleus (LGN). These cells are known as midget retinal ganglion cells due to the small sizes of their dendritic trees and cell bodies. http://purl.obolibrary.org/obo/CL_4023189 parasol ganglion cell of retina http://purl.obolibrary.org/obo/CL_0000740 retinal ganglion cell A retinal ganglion cell located in the ganglion cell layer of the retina. This cell projects to magnocellular cells in the lateral geniculate nucleus (LGN). They have large cell bodies and extensive, branching dendritic networks that contribute to their large receptive fields. http://purl.obolibrary.org/obo/CL_4030067 L5/6 near-projecting glutamatergic neuron http://purl.obolibrary.org/obo/CL_4023012 near-projecting glutamatergic cortical neuron A transcriptomically defined near-projecting glutamatergic neuron with a soma found in cortical layer 5/6. http://purl.obolibrary.org/obo/CL_4030068 L6 intratelencephalic projecting Car3 glutamatergic neuron http://purl.obolibrary.org/obo/CL_4030065 L6 intratelencephalic projecting glutamatergic neuron A transcriptomically distinct intratelencepalic-projecting glutamatergic neuron that expresses Car3 with a soma found in L6. http://purl.obolibrary.org/obo/CL_4040005 mesenchymal stem cell of apical papilla http://purl.obolibrary.org/obo/CL_0000134 mesenchymal stem cell A mesenchymal stem cell that is part of the apical papilla tooth root. http://purl.obolibrary.org/obo/CL_4033061 endothelial cell of central vein of liver http://purl.obolibrary.org/obo/CL_0002543 vein endothelial cell An endothelial cell that is part of a central vein of liver. http://purl.obolibrary.org/obo/GO_0141124 intracellular signaling cassette http://purl.obolibrary.org/obo/GO_0035556 intracellular signal transduction An intracellular signaling module that is part of larger signaling pathways that can be initiated either intracellularly or by cell surface receptors. Intracellular signaling cassettes are discrete signaling units that are often shared by multiple signaling pathways. http://purl.obolibrary.org/obo/GO_0170033 L-amino acid metabolic process http://purl.obolibrary.org/obo/GO_1901605 alpha-amino acid metabolic process The chemical reactions and pathways involving an L-amino acid. http://purl.obolibrary.org/obo/GO_0170041 non-proteinogenic amino acid metabolic process http://purl.obolibrary.org/obo/GO_0006520 amino acid metabolic process The chemical reactions and pathways involving non-proteingenic amino acids. http://purl.obolibrary.org/obo/GO_0170036 import into the mitochondrion http://purl.obolibrary.org/obo/GO_1990542 mitochondrial transmembrane transport The directed movement of substances from the cytosol into the mitochondrion. http://purl.obolibrary.org/obo/GO_0170037 export from the mitochondrion http://purl.obolibrary.org/obo/GO_1990542 mitochondrial transmembrane transport The directed movement of substances from the mitochondrion to the cytosol. http://purl.obolibrary.org/obo/UBERON_7770005 ascending colon epithelium http://purl.obolibrary.org/obo/UBERON_0000397 colonic epithelium An epithelial layer that lines the ascending colon. http://purl.obolibrary.org/obo/UBERON_7770006 transverse colon epithelium http://purl.obolibrary.org/obo/UBERON_0000397 colonic epithelium An epithelial layer that lines the transverse colon. http://purl.obolibrary.org/obo/UBERON_7770007 descending colon epithelium http://purl.obolibrary.org/obo/UBERON_0000397 colonic epithelium An epithelial layer that lines the descending colon. http://purl.obolibrary.org/obo/UBERON_7770008 sigmoid colon epithelium http://purl.obolibrary.org/obo/UBERON_0000397 colonic epithelium An epithelial layer that lines the sigmoid colon. http://purl.obolibrary.org/obo/UBERON_8600134 ascending colon lamina propria http://purl.obolibrary.org/obo/UBERON_0011189 lamina propria of large intestine The lamina propria that underlies the epithelial lining of the ascending colon. http://purl.obolibrary.org/obo/UBERON_8600135 descending colon lamina propria http://purl.obolibrary.org/obo/UBERON_0011189 lamina propria of large intestine The lamina propria that underlies the epithelial lining of the descending colon. http://purl.obolibrary.org/obo/UBERON_8600136 sigmoid colon lamina propria http://purl.obolibrary.org/obo/UBERON_0011189 lamina propria of large intestine The lamina propria that underlies the epithelial lining of the sigmoid colon. http://purl.obolibrary.org/obo/UBERON_8600137 transverse colon lamina propria http://purl.obolibrary.org/obo/UBERON_0011189 lamina propria of large intestine The lamina propria that underlies the epithelial lining of the transverse colon. http://purl.obolibrary.org/obo/UBERON_8600139 caecum lamina propria http://purl.obolibrary.org/obo/UBERON_0011189 lamina propria of large intestine The lamina propria that underlies the epithelial lining of the caecum. http://purl.obolibrary.org/obo/UBERON_8600140 rectum lamina propria http://purl.obolibrary.org/obo/UBERON_0011189 lamina propria of large intestine The lamina propria that underlies the epithelial lining of the rectum. http://purl.obolibrary.org/obo/CL_4033103 superior cervical ganglion NPY neuron http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron A sympathetic neuron that has the soma located in the superior cervical ganglion and expresses the marker neuropeptide Y (NPY). http://purl.obolibrary.org/obo/CL_4301614 mature myelinating oligodendrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4300367 oligodendrocyte (Mmus) A mature myelinating oligodendrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Cldn11 (Mmus), Anln (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1184 MOL NN_4. http://purl.obolibrary.org/obo/CL_4307084 CHOR NN_1 Tbc1d1 choroid plexus epithelial cell (Mmus) http://purl.obolibrary.org/obo/CL_4301608 choroid plexus epithelial cell (Mmus) A choroid plexus epithelial cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of 2900040C04Rik (Mmus), Tbc1d1 (Mmus). It is distinguished from other CHOR NN cells by expression of Tbc1d1. These cells are located in the Cerebellum, brain , in or close to the regions: Paraflocculus, choroid plexus . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5264 CHOR NN_1. http://purl.obolibrary.org/obo/CL_4304384 hypothalamic gonadotropin-releasing hormone neuron (Mmus) http://purl.obolibrary.org/obo/CL_0011111 hypothalamic gonadotropin-releasing hormone neuron A hypothalamic gonadotropin-releasing hormone neuron of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gnrh1 (Mmus). It is glutamatergic (inferred from expression of Gad1, Slc17a6, Gad2). These cells are located in the Hypothalamus, Olfactory areas, Pallidum, brain , in or close to the regions: Lateral septal nucleus, rostral (rostroventral) part, Medial septal nucleus, Diagonal band nucleus . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:2564 HY Gnrh1 Glut_1. http://purl.obolibrary.org/obo/CL_4033151 nodose ganglion PVALB neuron http://purl.obolibrary.org/obo/CL_0000101 sensory neuron A sensory neuron that has the soma located in the nodose ganglion and expresses the marker parvalbumin (PVALB). http://purl.obolibrary.org/obo/GO_0160275 negative regulation of white fat cell differentiation http://purl.obolibrary.org/obo/GO_0045599 negative regulation of fat cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of white fat cell differentiation. http://purl.obolibrary.org/obo/CL_4307134 BAM NN_1 Fos border associated macrophage (Mmus) http://purl.obolibrary.org/obo/CL_4301625 border associated macrophage (Mmus) A border associated macrophage of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Mrc1 (Mmus), Pf4 (Mmus), Fos (Mmus). It is distinguished from other BAM NN cells by expression of Fos. These cells are located in the Isocortex, Cerebellum, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5314 BAM NN_1. http://purl.obolibrary.org/obo/CL_0008061 GABA-Chol neuron http://purl.obolibrary.org/obo/CL_0000617 GABAergic neuron A neuron that releases both gamma-aminobutyric acid and acetylcholine as vesicular neurotransmitters. Examples include some types of striatal interneuron. http://purl.obolibrary.org/obo/CL_0008059 GABA-Gly neuron http://purl.obolibrary.org/obo/CL_1001509 glycinergic neuron A neuron that releases both gamma-aminobutyric acid and glycine as vesicular neurotransmitters. Examples include types of amacrine cell and types of cerebellar inhibitory neurons. http://purl.obolibrary.org/obo/CL_4307090 OPC NN_1 Rmi2 oligodendrocyte precursor cell (Mmus) http://purl.obolibrary.org/obo/CL_4300366 oligodendrocyte precursor cell (Mmus) A oligodendrocyte precursor cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Pdgfra (Mmus), Olig1 (Mmus), Rmi2 (Mmus), Col27a1 (Mmus). It is distinguished from other OPC NN_1 cells by expression of Rmi2, Col27a1. These cells are located in the Hypothalamus, Midbrain, Pallidum, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5270 OPC NN_1. http://purl.obolibrary.org/obo/CL_4307005 CB PLI GABA Ly6d Purkinje layer interneuron http://purl.obolibrary.org/obo/CL_4300349 Purkinje layer interneuron (Mmus) A Purkinje layer interneuron of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Ly6d (Mmus), Kit (Mmus). It is distinguished from other CB PLI Gly-Gaba cells by expression of Ly6d. It is GABAergic (inferred from expression of Gad1, Gad2, Slc32a1). These cells are located in the Cerebellum, brain , in or close to the regions: arbor vitae, Interposed nucleus, Nodulus (X) . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5185 CB PLI Gly-Gaba_4. http://purl.obolibrary.org/obo/CL_4307042 Astro-TE NN_2 Clstn2 astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301592 Astro-TE NN_2 astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gm6145 (Mmus), E330013P04Rik (Mmus), Slc39a12 (Mmus). It is distinguished from other Astro-TE NN_2 cells by expression of Clstn2. These cells are located in the Hippocampal region , in or close to the regions: Dentate gyrus, molecular layer, Dentate gyrus, polymorph layer, Field CA3, stratum oriens, Dentate gyrus, granule cell layer . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5222 Astro-TE NN_2. http://purl.obolibrary.org/obo/CL_4300354 cerebellar granule cell (Mmus) http://purl.obolibrary.org/obo/CL_4300029 cerebellar glutamatergic neuron (Mmus) A cerebellar granule cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gabra6 (Mmus), Ror1 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Subclass:314 CB Granule Glut. http://purl.obolibrary.org/obo/CL_4307026 Bergmann glial cell (Mmus) http://purl.obolibrary.org/obo/CL_0000644 Bergmann glial cell A Bergmann glial cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gpr37l1 (Mmus), Ctxn3 (Mmus). It is distinguished from other Astro-Epen cells by expression of Gpr37l1, Ctxn3. These cells are located in the Cerebellum, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5206 Bergmann NN_1. http://purl.obolibrary.org/obo/CL_4307012 CBX MLI Cdh22 Gaba molecular layer interneuron (Mmus) http://purl.obolibrary.org/obo/CL_4300028 cerebellar GABAergic neuron (Mmus) A molecular layer interneuron of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Cdh1 (Mmus), Acvr1c (Mmus), Adamts15 (Mmus), Pax2 (Mmus). It is distinguished from other CB GABA cells by expression of Cdh1, Acvr1c, Adamts15, Pax2. It is GABAergic (inferred from expression of Gad1, Gad2, Slc32a1). These cells are located in the Cerebellum, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5192 CBX MLI Cdh22 Gaba_1. http://purl.obolibrary.org/obo/CL_4300358 subcortical astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_0000127 astrocyte A transcriptomically defined type of astrocyte located predominantly in the ventral and posterior subcortical areas. It is distinguished from other cells in the brain by selective expression of Aqp4 (Mmus), Cd38 (Mmus), Agt (Mmus), Itih3 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Subclass:318 Astro-NT NN. http://purl.obolibrary.org/obo/CL_4033156 jugular ganglion SPARCL1 neuron http://purl.obolibrary.org/obo/CL_0000101 sensory neuron A sensory neuron that has the soma located in the jugular ganglion and expresses the marker SPARC-like protein 1 (SPARCL1). http://purl.obolibrary.org/obo/CL_4072002 myelin-forming oligodendrocyte http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure A postmitotic and differentiated oligodendrocyte derived from a oligodendrocyte progenitor cell. A myelin-forming oligodendrocyte begins the expression of myelin genes and actively engages in the myelination process. In mice and humans, it is characterized by the upregulation of the key myelin-associated markers Mbp and Opalin. Additionally, Ctps (CTP synthase) shows peak expression at this stage, suggesting a heightened demand for nucleotide biosynthesis during membrane expansion and myelin production. http://purl.obolibrary.org/obo/GO_0098690 glycinergic synapse http://purl.obolibrary.org/obo/GO_0045202 synapse A synapse that uses glycine as a neurotransmitter. http://purl.obolibrary.org/obo/GO_0120032 regulation of plasma membrane bounded cell projection assembly http://purl.obolibrary.org/obo/GO_0120035 regulation of plasma membrane bounded cell projection organization Any process that modulates the rate, frequency, or extent of plasma membrane bounded cell projection assembly. http://purl.obolibrary.org/obo/GO_0120033 negative regulation of plasma membrane bounded cell projection assembly http://purl.obolibrary.org/obo/GO_0120032 regulation of plasma membrane bounded cell projection assembly Any process that stops, prevents or reduces the frequency, rate or extent of plasma membrane bounded cell projection assembly. http://purl.obolibrary.org/obo/GO_0120034 positive regulation of plasma membrane bounded cell projection assembly http://purl.obolibrary.org/obo/GO_0120032 regulation of plasma membrane bounded cell projection assembly Any process that activates or increases the frequency, rate or extent of plasma membrane bounded cell projection assembly. http://purl.obolibrary.org/obo/GO_0061868 hepatic stellate cell migration http://purl.obolibrary.org/obo/GO_0010761 fibroblast migration The orderly movement of a hepatic stellate cell from one site to another. http://purl.obolibrary.org/obo/GO_0061869 regulation of hepatic stellate cell migration http://purl.obolibrary.org/obo/GO_0010762 regulation of fibroblast migration Any process that modulates the frequency, rate or extent of hepatic stellate cell migration. http://purl.obolibrary.org/obo/GO_0061870 positive regulation of hepatic stellate cell migration http://purl.obolibrary.org/obo/GO_0061869 regulation of hepatic stellate cell migration Any process that increases the frequency, rate or extent of hepatic stellate cell migration. http://purl.obolibrary.org/obo/GO_0061871 negative regulation of hepatic stellate cell migration http://purl.obolibrary.org/obo/GO_0061869 regulation of hepatic stellate cell migration Any process that stops, prevents or reduces the frequency, rate or extent of hepatic stellate cell migration. http://purl.obolibrary.org/obo/GO_0140131 positive regulation of lymphocyte chemotaxis http://purl.obolibrary.org/obo/GO_1901623 regulation of lymphocyte chemotaxis Any process that activates or increases the frequency, rate or extent of lymphocyte chemotaxis. http://purl.obolibrary.org/obo/UBERON_0036264 zygomaticotemporal nerve http://purl.obolibrary.org/obo/UBERON_0011779 nerve of head region The zygomaticotemporal nerve or zygomaticotemporal branch (temporal branch) is derived from the maxillary branch of the trigeminal nerve (Cranial nerve V). It runs along the lateral wall of the orbit in a groove in the zygomatic bone, receives a branch of communication from the lacrimal, and passes through zygomaticotemporal foramen in the zygomatic bone to enter the temporal fossa. It ascends between the bone, and substance of the Temporalis muscle, pierces the temporal fascia about 2.5 cm. above the zygomatic arch, and is distributed to the skin of the side of the forehead, and communicates with the facial nerve and with the auriculotemporal branch of the mandibular nerve. As it pierces the temporal fascia, it gives off a slender twig, which runs between the two layers of the fascia to the lateral angle of the orbit. http://purl.obolibrary.org/obo/GO_0140227 serotonin-gated cation-selective signaling pathway http://purl.obolibrary.org/obo/GO_1990806 ligand-gated ion channel signaling pathway The series of molecular signals initiated by serotonin binding to a seratonin receptor on the surface of the target cell, followed by the movement of ions through a channel in the receptor complex. Ends with regulation of a downstream cellular process, e.g. transcription. http://purl.obolibrary.org/obo/STATO_0000416 precision http://purl.obolibrary.org/obo/STATO_0000607 proportion precision or positive predictive value is defined as the proportion of the true positives against all the positive results (both true positives and false positives) A proportion in which the numerator represents the correctly detected items within the denominator that represents all items detected. http://purl.obolibrary.org/obo/GO_0140318 protein transporter activity http://purl.obolibrary.org/obo/GO_0005215 transporter activity Directly binding to a specific protein and delivering it to a specific cellular location. http://purl.obolibrary.org/obo/GO_0110141 L-glutamate import into mitochondrion http://purl.obolibrary.org/obo/GO_0015813 L-glutamate transmembrane transport The process in which L-glutamate is transported from the cytosol into the mitochondrial matrix. http://purl.obolibrary.org/obo/GO_0150102 negative regulation of monocyte activation http://purl.obolibrary.org/obo/GO_0002695 negative regulation of leukocyte activation Any process that stops, prevents or reduces the frequency, rate or extent of monocyte activation. http://purl.obolibrary.org/obo/CL_0011013 motile sperm cell http://purl.obolibrary.org/obo/CL_0000219 motile cell A sperm cell that is cabaple of motion (motility). http://purl.obolibrary.org/obo/CL_0011014 non-motile sperm cell http://purl.obolibrary.org/obo/CL_0000019 sperm A sperm cell that is not cabaple of motion (motility). http://purl.obolibrary.org/obo/CL_0011015 amoeboid sperm cell http://purl.obolibrary.org/obo/CL_0011013 motile sperm cell A motile sperm cell that contain no F-actin, and their motility is powered by a dynamic filament system. http://purl.obolibrary.org/obo/CL_0011016 flagellated sperm cell http://purl.obolibrary.org/obo/CL_0011013 motile sperm cell A motile sperm cell that contains a slender threadlike microscopic appendage that enables motion. http://purl.obolibrary.org/obo/CL_0011018 lymphoid tissue–inducer cell http://purl.obolibrary.org/obo/CL_0001071 group 3 innate lymphoid cell A group 3 innate lymphoid cell that express ROR gamma t and IL-7R alpha in the absence of lineage markers (e.g. CD3, CD19, B220, CD11c, Gr-1), with the functional ability to interact with mesenchymal cells through lymphotoxin and tumor necrosis factor. Lymphoid tissue-inducer cells are key to the development of lymph nodes and Peyer’s patches. http://purl.obolibrary.org/obo/GO_0120222 regulation of blastocyst development http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of blastocyst development. http://purl.obolibrary.org/obo/UBERON_8000006 left side of back http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure Left part of the organism dorsal to a horizontal plane and bounded on one side by the same transverse plane. http://purl.obolibrary.org/obo/UBERON_8000007 right side of back http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure Right part of the organism dorsal to a horizontal plane and bounded on one side by the same transverse plane. http://purl.obolibrary.org/obo/UBERON_8300000 skin of scalp http://purl.obolibrary.org/obo/UBERON_0001084 skin of head A zone of skin that is part of a scalp. http://purl.obolibrary.org/obo/UBERON_8300001 right forelimb http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure A forelimb that is on the right side of a pectoral complex. http://purl.obolibrary.org/obo/UBERON_8300002 left forelimb http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure A forelimb that is on the left side of a pectoral complex. http://purl.obolibrary.org/obo/UBERON_8300003 right hindlimb http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure A hindlimb that is on the right side of a pelvic complex. http://purl.obolibrary.org/obo/UBERON_8300004 left hindlimb http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure A hindlimb that is on the left side of a pelvic complex. http://purl.obolibrary.org/obo/PATO_0070020 stellate pyramidal morphology http://purl.obolibrary.org/obo/PATO_0070017 standard pyramidal morphology A pyramidal cell morphology that inheres in neurons which lack a tuft formation but extend to small radial distances forming a star-like shape. http://purl.obolibrary.org/obo/CL_4023094 tufted pyramidal neuron http://purl.obolibrary.org/obo/CL_0000598 pyramidal neuron A pyramidal neuron which has a distinctive tuft formation, distal from the soma. http://purl.obolibrary.org/obo/UBERON_8410001 small intestine venule http://purl.obolibrary.org/obo/UBERON_0001979 venule Venule of villus of small intestine. http://purl.obolibrary.org/obo/UBERON_8410002 small intestine lymphatic vessel http://purl.obolibrary.org/obo/UBERON_0001473 lymphatic vessel A lymphatic vessel that supplies the small intestine. http://purl.obolibrary.org/obo/UBERON_8410004 small intestine arteriole http://purl.obolibrary.org/obo/UBERON_0001980 arteriole Arteriole of villus of small intestine. http://purl.obolibrary.org/obo/UBERON_8410008 venule of anorectum http://purl.obolibrary.org/obo/UBERON_0001979 venule A venule that is located in the anorectum. http://purl.obolibrary.org/obo/UBERON_8410009 arteriole of anorectum http://purl.obolibrary.org/obo/UBERON_0001980 arteriole An arteriole that is located in the anorectum. http://purl.obolibrary.org/obo/UBERON_8410015 arteriole of colon http://purl.obolibrary.org/obo/UBERON_0001980 arteriole An arteriole located in the colon. http://purl.obolibrary.org/obo/UBERON_8410032 trabecular sinus of lymph node http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space The trabecular sinus is the lymph-filled space outside the trabeculae between lobules of the lymph node. This is a continuation of the subcapsular sinus which receives the afferent vessels and is present beneath the capsule. This space is traversed by both reticular fibers and cells in the lymph. http://purl.obolibrary.org/obo/UBERON_8410035 medullary arteriole of lymph node http://purl.obolibrary.org/obo/UBERON_8410042 arteriole of lymph node An arteriole that arises from the hilar artery of a lymph node and radiates centrifugally, branching in the medulla. http://purl.obolibrary.org/obo/UBERON_8410036 medullary venule of lymph node http://purl.obolibrary.org/obo/UBERON_8410041 venule of lymph node Medullary venules are a continuation of high endothelial venules which condense repeatedly in the interfollicular cortex and peripheral deep cortical unit and then transition to medullary venules at the corticomedullary junction. The medullary venules condense and return centripetally to the hilar vein. http://purl.obolibrary.org/obo/UBERON_8410041 venule of lymph node http://purl.obolibrary.org/obo/UBERON_0001979 venule A venule that is part of a lymph node. http://purl.obolibrary.org/obo/UBERON_8410042 arteriole of lymph node http://purl.obolibrary.org/obo/UBERON_0001980 arteriole An arteriole that is part of a lymph node. http://purl.obolibrary.org/obo/UBERON_8410043 bronchus submucosal gland http://purl.obolibrary.org/obo/UBERON_8410077 airway submucosal gland A submucosal gland located in a bronchus. http://purl.obolibrary.org/obo/UBERON_8410048 venule of colon http://purl.obolibrary.org/obo/UBERON_0001979 venule A venule located in the colon. http://purl.obolibrary.org/obo/UBERON_8410050 anorectum http://purl.obolibrary.org/obo/UBERON_0004921 subdivision of digestive tract A subdivision of the digestive tract in humans that includes the rectum, the anal canal and the anus. http://purl.obolibrary.org/obo/UBERON_8410051 lymphatic vessel of colon http://purl.obolibrary.org/obo/UBERON_0001473 lymphatic vessel A lymphatic vessel located in the colon. http://purl.obolibrary.org/obo/UBERON_8410056 capillary of anorectum http://purl.obolibrary.org/obo/UBERON_0001982 capillary A capillary that is part of the anorectum. http://purl.obolibrary.org/obo/UBERON_8410057 capillary of colon http://purl.obolibrary.org/obo/UBERON_0001982 capillary A capillary that is part of the colon. http://purl.obolibrary.org/obo/PATO_0070027 bitufted dendrite cell morphology http://purl.obolibrary.org/obo/PATO_0010006 cell morphology A cell morphology that inheres in neurons with dendrites that are bidirectional, emerging from opposite ends of the soma, with the two arbors extending in radial or tangential directions. http://purl.obolibrary.org/obo/GO_0140694 membraneless organelle assembly http://purl.obolibrary.org/obo/GO_0070925 organelle assembly The aggregation, arrangement and bonding together of a set of components to form a non-membrane-bounded organelle. http://purl.obolibrary.org/obo/CL_0009006 enteroendocrine cell of small intestine http://purl.obolibrary.org/obo/CL_1001598 small intestine secretory cell An enteroendocrine cell that is located in the small intestine. http://purl.obolibrary.org/obo/CL_0009037 lymph node mantle zone B cell http://purl.obolibrary.org/obo/CL_0000236 B cell A B lymphocyte that resides in the mantle zone of the lymph node germinal center. These are generally IgM and IgD positive activated B cells that form a 'corona' around the germinal center and are part of the establishment of a secondary lymphatic follicule. http://purl.obolibrary.org/obo/CL_0009040 stromal cell of lamina propria of colon http://purl.obolibrary.org/obo/CL_0009021 stromal cell of lamina propria of large intestine A stromal cell found in the lamina propria of the colon. http://purl.obolibrary.org/obo/CL_0009041 tuft cell of colon http://purl.obolibrary.org/obo/CL_0011108 colon epithelial cell A tuft cell that is part of the colonic epithelium, primarily adapted for microbial sensing in the dense colonic microbiota. Unlike its small intestinal counterpart, it does not participate in parasite-driven tuft cell–ILC2 circuits. Instead, it detects bacterial metabolites via taste-signaling pathways (Strine and Craig, 2022). The colonic tuft cell plays a key role in epithelial repair, modulates inflammatory responses through IL-25 secretion, and contributes to intestinal homeostasis by balancing microbiome interactions (Sebastian et al., 2021). http://purl.obolibrary.org/obo/CL_0009042 enteroendocrine cell of colon http://purl.obolibrary.org/obo/CL_1001516 intestinal enteroendocrine cell An enteroendocrine cell that is located in the colon. http://purl.obolibrary.org/obo/CL_0009043 intestinal crypt stem cell of colon http://purl.obolibrary.org/obo/CL_0009016 intestinal crypt stem cell of large intestine An intestinal crypt stem cell that is located in the crypt of Lieberkuhn of colon. http://purl.obolibrary.org/obo/CL_0009044 lymphocyte of small intestine lamina propria http://purl.obolibrary.org/obo/CL_0000542 lymphocyte A lymphocyte that resides in the lamina propria of the small intestine. Lamina propria leukocytes and intraepithelial lymphocytes are the effector compartments of the gut mucosal immune system. Lymphocytes circulate through gut associated lymphoid tissues until recruitment by intestinal antigens. They are involved in the gut immune response. http://purl.obolibrary.org/obo/CL_0009049 smooth muscle cell of high endothelial venule of lymph node http://purl.obolibrary.org/obo/CL_0008035 microcirculation associated smooth muscle cell A layer of smooth muscle cells that forms the outer layer of the high endothelial venule of lymph node and pumps to allow flow of lymph fluid carrying lymphocytes. http://purl.obolibrary.org/obo/CL_0009062 germinal center T cell http://purl.obolibrary.org/obo/CL_0002038 T follicular helper cell A specialized type of CD4 positive T cell, the follicular helper T cell (TFH cell), that upregulates CXCR5 expression to enable its follicular localization. These specialised T cells reside in the germinal center of the lymph node. http://purl.obolibrary.org/obo/CL_0009064 lymph node paracortex T cell http://purl.obolibrary.org/obo/CL_0000084 T cell A T cell located in the lymph node paracortex, where macrophages and dendritic cells present antigenic peptides to these naïve T cells, stimulating them to become activated helper T cells or cytotoxic T lymphocytes. http://purl.obolibrary.org/obo/CL_0009067 vacuolated fetal-type enterocyte http://purl.obolibrary.org/obo/CL_0002254 epithelial cell of small intestine An enterocyte found in the small intestine of newborn mammals and characterized by the presence of an apical canalicular system (ACS) leading to production of large vacuoles, important for colostral macromolecule uptake. After birth, the vacuolated fetal-type enterocytes are replaced with enterocytes lacking an ACS. http://purl.obolibrary.org/obo/CL_0009068 CD8aa(I) thymocyte http://purl.obolibrary.org/obo/CL_0000893 thymocyte An unconventional T lymphocyte population within the thymic medulla that is potentially a thymic resident population. http://purl.obolibrary.org/obo/CL_0009069 CD8aa(II) thymocyte http://purl.obolibrary.org/obo/CL_0000893 thymocyte An unconventional T lymphocyte population within the thymic medulla that expresses both alpha/beta and gamma/delta T cell signatures. http://purl.obolibrary.org/obo/CL_0009070 corticomedullary thymic epithelial cell http://purl.obolibrary.org/obo/CL_0002293 epithelial cell of thymus A thymic epithelial cell located at the corticomedullary junction. http://purl.obolibrary.org/obo/CL_0009071 medullary thymic epithelial cell type 1 http://purl.obolibrary.org/obo/CL_0002365 medullary thymic epithelial cell A thymic medullary epithelial cell considered to be a pre-AIRE mTEC population. http://purl.obolibrary.org/obo/CL_0009072 medullary thymic epithelial cell type 2 http://purl.obolibrary.org/obo/CL_0002365 medullary thymic epithelial cell A thymic medullary epithelial cell that expresses AIRE or other canonical markers of mature mTECs like Fezf2. http://purl.obolibrary.org/obo/CL_0009073 medullary thymic epithelial cell type 3 http://purl.obolibrary.org/obo/CL_0002365 medullary thymic epithelial cell A thymic medullary epithelial cell considered to be a post-AIRE cell. This group of AIRE-mTECs is heterogeneous and also includes mTECs within Hassall's Corpuscles. http://purl.obolibrary.org/obo/CL_0009074 medullary thymic epithelial cell type 4 http://purl.obolibrary.org/obo/CL_0002365 medullary thymic epithelial cell A thymic medullary epithelial cell that expresses typical tuft cell markers instead of classical mTEC or cTEC markers. This population has a bulbous-like structure. http://purl.obolibrary.org/obo/CL_0009075 myo-medullary thymic epithelial cell http://purl.obolibrary.org/obo/CL_0002365 medullary thymic epithelial cell A thymic medullary epithelial cell that expresses muscle-specific biomarkers. http://purl.obolibrary.org/obo/CL_0009076 neuro-medullary thymic epithelial cell http://purl.obolibrary.org/obo/CL_0002365 medullary thymic epithelial cell A thymic medullary epithelial cell that expresses neuroendocrine biomarkers. http://purl.obolibrary.org/obo/CL_0009077 subcapsular thymic epithelial cell http://purl.obolibrary.org/obo/CL_0002364 cortical thymic epithelial cell A thymic epithelial cell located within the subcapsular region of the thymus. http://purl.obolibrary.org/obo/CL_0009078 thymic fibroblast type 1 http://purl.obolibrary.org/obo/CL_4030001 stromal cell of thymus A fibroblast located in the thymic capsule. http://purl.obolibrary.org/obo/CL_0009079 thymic fibroblast type 2 http://purl.obolibrary.org/obo/CL_4030001 stromal cell of thymus A fibroblast located between thymic lobules. http://purl.obolibrary.org/obo/CL_0009080 tuft cell of small intestine http://purl.obolibrary.org/obo/CL_0002254 epithelial cell of small intestine A tuft cell located in the small intestine. http://purl.obolibrary.org/obo/CL_0009081 specified double negative thymocyte (Homo sapiens) http://purl.obolibrary.org/obo/CL_0002489 double negative thymocyte The human equivalent of a DN2 thymocyte; typically contains two phases, in the latter of which these thymocytes begin the process of beta selection. http://purl.obolibrary.org/obo/CL_0009082 committed double negative thymocyte (Homo sapiens) http://purl.obolibrary.org/obo/CL_0002489 double negative thymocyte The human equivalent of a DN3 thymocyte; these thymocytes finish the process of beta selection. http://purl.obolibrary.org/obo/CL_0009083 rearranging double negative thymocyte (Homo sapiens) http://purl.obolibrary.org/obo/CL_0002489 double negative thymocyte The human equivalent of a DN4 thymocyte. http://purl.obolibrary.org/obo/CL_0011031 monocyte-derived dendritic cell http://purl.obolibrary.org/obo/CL_0000782 myeloid dendritic cell A dendritic cell that develops from a monocyte. http://purl.obolibrary.org/obo/CL_0011032 lysosome-rich enterocyte http://purl.obolibrary.org/obo/CL_0000584 enterocyte An enterocyte that possesses a large supranuclear vacuolar system that preferentially internalizes dietary protein via receptor-mediated and fluid-phase endocytosis for intracellular digestion and trans-cellular transport. In zebrafish these cells are located in the posterior region of the mid intestine throughout life. In mammals they are found in the ileum pre-weaning and later are replaced by mature enterocytes. http://purl.obolibrary.org/obo/CL_4023020 dynamic gamma motor neuron http://purl.obolibrary.org/obo/CL_0008037 gamma motor neuron A gamma motor neuron that innervates dynamic nuclear bag fibers (bag1 fibers) and enhances the sensitivities of Ia sensory neurons. They alter muscle spindle sensitivity and increases its discharge in response to velocity of muscle length (rather than just magnitude). http://purl.obolibrary.org/obo/CL_4023021 static gamma motor neuron http://purl.obolibrary.org/obo/CL_0008037 gamma motor neuron A gamma motor neuron that innervates static nuclear bag fibers (bag2 fibers) and increases their firing, in response to an increase in the magnitude of change in length, and controls the static sensitivity of the stretch reflex. http://purl.obolibrary.org/obo/CL_4023097 arachnoid barrier cell http://purl.obolibrary.org/obo/CL_4023058 mesothelial fibroblast of the leptomeninx A mesothelial fibroblast of the arachnoid barrier layer. Arachnoid barrier cells make up the tight-junctioned layer in the leptomeninx that functions as the physiologic barrier between the cerebrospinal fluid in the subarachnoid space and the fenestrated capillaries in the dura. http://purl.obolibrary.org/obo/CL_4023108 oxytocin-secreting magnocellular cell http://purl.obolibrary.org/obo/CL_0011003 magnocellular neurosecretory cell A magnocellular neurosecretory cell that is capable of producing and secreting oxytocin. http://purl.obolibrary.org/obo/CL_4023109 vasopressin-secreting magnocellular cell http://purl.obolibrary.org/obo/CL_0011003 magnocellular neurosecretory cell A magnocellular neurosecretory cell that is capable of producing and secreting vasopressin. http://purl.obolibrary.org/obo/CL_4023110 amygdala pyramidal neuron http://purl.obolibrary.org/obo/CL_0012001 neuron of the forebrain A pyramidal neuron with soma located in the amygdala. http://purl.obolibrary.org/obo/CL_4023111 cerebral cortex pyramidal neuron http://purl.obolibrary.org/obo/CL_0010012 cerebral cortex neuron A pyramidal neuron with soma located in the cerebral cortex. http://purl.obolibrary.org/obo/CL_4023112 vestibular afferent neuron http://purl.obolibrary.org/obo/CL_0000101 sensory neuron An afferent neuron of the vestibular system that innervate the base of the hair cell and increase or decrease their neural firing rate as the receptor cell is excited or inhibited. http://purl.obolibrary.org/obo/CL_4023113 bouton vestibular afferent neuron http://purl.obolibrary.org/obo/CL_4023112 vestibular afferent neuron A vestibular afferent neuron that makes bouton synapses to type II hair cells. http://purl.obolibrary.org/obo/CL_4023114 calyx vestibular afferent neuron http://purl.obolibrary.org/obo/CL_4023112 vestibular afferent neuron A vestibular afferent neuron which posseses a unique postsynaptic terminal, the calyx, which completely covers the basolateral walls of type I hair cells and receives input from multiple ribbon synapses. http://purl.obolibrary.org/obo/CL_4023115 type 1 spiral ganglion neuron http://purl.obolibrary.org/obo/UBERON_0000122 neuron projection bundle A spiral ganglion neuron that innervates inner hair cells. Type 1 spiral ganglion neurons are myelinated and bipolar. http://purl.obolibrary.org/obo/CL_4023116 type 2 spiral ganglion neuron http://purl.obolibrary.org/obo/UBERON_0000122 neuron projection bundle A spiral ganglion neuron that innervates outer hair cells. Type 1 spiral ganglion neurons are unmyelinated and unipolar. http://purl.obolibrary.org/obo/CL_4023118 L5/6 non-Martinotti sst GABAergic interneuron (Mmus) http://purl.obolibrary.org/obo/CL_0010011 cerebral cortex GABAergic interneuron A sst GABAergic interneuron does not have Martinotti morphology with a soma found in L5/6 of the cerebral cortex. http://purl.obolibrary.org/obo/CL_4023119 displaced amacrine cell http://purl.obolibrary.org/obo/CL_0000561 amacrine cell A subpopulation of amacrine cell that migrate further than other amacrine cells, and come to lie basal to the inner plexiform layer (IPL) in the ganglion cell layer. Displaced amacrine cells still have their neurites extending apically into the IPL, and therefore exhibit an inverted polarity with respect to the other amacrine cells. http://purl.obolibrary.org/obo/CL_4023120 cochlea auditory hair cell http://purl.obolibrary.org/obo/CL_0002374 ear hair cell An auditory hair cell found in the cochlea. http://purl.obolibrary.org/obo/UBERON_8410038 high endothelial venule of lymph node http://purl.obolibrary.org/obo/UBERON_8410041 venule of lymph node A high endothelial venule that is part of a of lymph node. http://purl.obolibrary.org/obo/UBERON_8410065 lymph node follicle marginal zone http://purl.obolibrary.org/obo/UBERON_0001744 lymphoid tissue Histologically, the marginal zone pattern of the lymph node is characterized by lymphoid follicles with three distinct layers. The inner layer is composed of follicular center zones, the middle layer of darkly stained mantle zones, and the outer layer of marginal zones. However, the marginal zone pattern is rarely seen in reactive lymph nodes except for mesenteric lymph nodes. Lymph node marginal zones are populated by marginal zone B cells which express CD19 and CD20 and have the phenotypic features of memory B cells. http://purl.obolibrary.org/obo/UBERON_8410066 lymph node paracortex http://purl.obolibrary.org/obo/UBERON_0001744 lymphoid tissue The lymph node paracortex is the middle layer of the lymph node and is mostly populated by T cells and dendritic cells. The paracortex also contains specialised blood vessels called high endothelial venules which allow lymphocytes to enter the node. http://purl.obolibrary.org/obo/UBERON_8440000 cortical layer II/III http://purl.obolibrary.org/obo/UBERON_8440004 laminar subdivision of the cortex A laminar subdivision of the neocortex that is comprised of a part of layer II and a part of layer III. http://purl.obolibrary.org/obo/UBERON_8440001 cortical layer IV/V http://purl.obolibrary.org/obo/UBERON_8440004 laminar subdivision of the cortex A laminar subdivision of the neocortex that is comprised of a part of layer IV and a part of layer V. http://purl.obolibrary.org/obo/UBERON_8440002 cortical layer V/VI http://purl.obolibrary.org/obo/UBERON_8440004 laminar subdivision of the cortex A laminar subdivision of the neocortex that is comprised of a part of layer V and a part of layer VI. http://purl.obolibrary.org/obo/UBERON_8440003 cortical layer VIb http://purl.obolibrary.org/obo/UBERON_0002301 layer of neocortex The deepest layer of the neocortex. While layer 6b is considered part of layer 6, it is distinct morphologically, genetically, and developmentally from the rest of layer 6. Neurons in L6b project to cortical targets and higher-order thalamus and develop from a precursor population that arises from the subplate. http://purl.obolibrary.org/obo/CL_0009089 lung pericyte http://purl.obolibrary.org/obo/CL_0000669 pericyte A pericyte cell that is part of a lung. http://purl.obolibrary.org/obo/CL_0009096 esophagus non-keratinized squamous epithelial cell http://purl.obolibrary.org/obo/CL_0002252 epithelial cell of esophagus Any cell that is part of the esophageal non-keratinized stratified squamous epithelium. In humans, the esophagus, which requires flexibility to accommodate swallowing of a bolus, is covered with a non-keratinized epithelium. http://purl.obolibrary.org/obo/CL_0009098 fetal and neonatal skeletal muscle fiber http://purl.obolibrary.org/obo/CL_0008002 skeletal muscle fiber A skeletal muscle fiber found at the fetal and neonatal stages. In mammalian fetuses and neonates, skeletal muscle expresses myosin heavy chain-neonatal (MyHC-neo, encoded by the MYH8 gene). This expression disappears shortly after birth and is replaced by expression of adult heavy chain myosins. http://purl.obolibrary.org/obo/CL_0009110 lymphatic endothelial cell of medulla ceiling http://purl.obolibrary.org/obo/CL_0009115 lymph node lymphatic vessel endothelial cell A lymphatic endothelial cell located in the ceiling part of a lymph node medulla. http://purl.obolibrary.org/obo/CL_0009112 centroblast http://purl.obolibrary.org/obo/CL_0000844 germinal center B cell A germinal center B cell found in a lymph node germinal center dark zone. http://purl.obolibrary.org/obo/CL_4030017 epithelial cell of late distal convoluted tubule http://purl.obolibrary.org/obo/CL_1000849 kidney distal convoluted tubule epithelial cell An epithelial cell located in the late distal convoluted tubule. http://purl.obolibrary.org/obo/CL_4030016 epithelial cell of early distal convoluted tubule http://purl.obolibrary.org/obo/CL_1000849 kidney distal convoluted tubule epithelial cell An epithelial cell located in the early distal convoluted tubule. http://purl.obolibrary.org/obo/UBERON_8450002 excretory system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system An anatomical system that eliminates waste products that arise as a result of metabolic activity. http://purl.obolibrary.org/obo/CL_4032001 reelin GABAergic cortical interneuron http://purl.obolibrary.org/obo/CL_0010011 cerebral cortex GABAergic interneuron A GABAergic interneuron located in the cerebral cortex that expresses reelin (rln). http://purl.obolibrary.org/obo/CL_0003045 M12 retinal ganglion cell http://purl.obolibrary.org/obo/CL_0003001 bistratified retinal ganglion cell A bistratified ganglion cell with larger, asymetric dendritic fields that terminate in S2 and S4. http://purl.obolibrary.org/obo/CL_0003039 M8 retinal ganglion cell http://purl.obolibrary.org/obo/CL_0000740 retinal ganglion cell A monostratified retinal ganglion cell with large soma and medium dendritic field, with dense dendritic arbor. http://purl.obolibrary.org/obo/CL_0003031 M3-ON retinal ganglion cell http://purl.obolibrary.org/obo/CL_4023032 ON retinal ganglion cell A monostratified retinal ganglion cell that has post synaptic terminals in sublaminar layer S4 and is depolarized by illumination of its receptive field center. http://purl.obolibrary.org/obo/CL_0003005 G4 retinal ganglion cell http://purl.obolibrary.org/obo/CL_0000740 retinal ganglion cell A mono-stratified retinal ganglion cell that has a small dendritic field and dense dendritic arbor. http://purl.obolibrary.org/obo/CL_0004139 retinal ganglion cell A2 outer http://purl.obolibrary.org/obo/CL_0004138 retinal ganglion cell A2 A retinal ganglion A2 cell with dendrites terminating in S2. http://purl.obolibrary.org/obo/CL_0004124 retinal ganglion cell C1 http://purl.obolibrary.org/obo/CL_0003024 retinal ganglion cell C inner A retinal ganglion cell C inner that has medium dendritic diversity. http://purl.obolibrary.org/obo/CL_0004235 AB broad diffuse-1 amacrine cell http://purl.obolibrary.org/obo/CL_0004252 medium field retinal amacrine cell An amacrine cell with a medium dendritic field and post-synaptic terminals in S2 and S3. This cell type releases the neurotransmitter gamma-aminobutyric acid (GABA). http://purl.obolibrary.org/obo/CL_0004231 recurving diffuse amacrine cell http://purl.obolibrary.org/obo/CL_0004251 narrow field retinal amacrine cell A broadly stratifying amacrine cell with a small dendritic field and a complex dendritic arbor. Recurving diffuse amacrine cells have post-synaptic terminals in S2, S3, and S4. http://purl.obolibrary.org/obo/CL_0003024 retinal ganglion cell C inner http://purl.obolibrary.org/obo/CL_0004116 retinal ganglion cell C A retinal ganglion cell C with medium cell bodies and large dendritic field. http://purl.obolibrary.org/obo/UBERON_8480029 skin of external genitalia http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure A zone of skin that is part of the external genitalia. http://purl.obolibrary.org/obo/CL_4033038 lung resident memory CD4-positive, alpha-beta T cell http://purl.obolibrary.org/obo/CL_0000897 CD4-positive, alpha-beta memory T cell An alpha-beta CD4 T cell that resides in the lung. http://purl.obolibrary.org/obo/CL_4033039 lung resident memory CD8-positive, alpha-beta T cell http://purl.obolibrary.org/obo/CL_0000909 CD8-positive, alpha-beta memory T cell An alpha-beta CD8 T cell that resides in the lung. http://purl.obolibrary.org/obo/CL_4033049 taste receptor cell of tongue http://purl.obolibrary.org/obo/CL_0002319 neural cell A taste receptor cell that is part of a taste bud of a tongue. http://purl.obolibrary.org/obo/CL_4033050 catecholaminergic neuron http://purl.obolibrary.org/obo/CL_0000540 neuron A neuron that releases catecholamine as a neurotransmitter. http://purl.obolibrary.org/obo/UBERON_8600010 bronchial submucosal gland ciliated duct http://purl.obolibrary.org/obo/UBERON_8600014 submucosal gland ciliated duct A ciliated duct part of a bronchial submucosal gland. http://purl.obolibrary.org/obo/UBERON_8600011 tracheal submucosal gland ciliated duct http://purl.obolibrary.org/obo/UBERON_8600014 submucosal gland ciliated duct A ciliated duct part of a tracheal submucosal gland. http://purl.obolibrary.org/obo/UBERON_8600012 submucosal gland acinus http://purl.obolibrary.org/obo/UBERON_0014717 mucous acinus A spherical or tubular structure in a submucosal gland that produces and secretes mucus and other substances into the ducts leading to the surface epithelium. http://purl.obolibrary.org/obo/UBERON_8600014 submucosal gland ciliated duct http://purl.obolibrary.org/obo/UBERON_0000058 duct A ciliated tubular structure in a submucosal gland connecting the submucosal gland collecting duct with the surface epithelium. http://purl.obolibrary.org/obo/GO_0160307 protein biosynthetic process http://purl.obolibrary.org/obo/GO_0009059 macromolecule biosynthetic process The chemical reactions and pathways resulting in the formation of protein. http://purl.obolibrary.org/obo/GO_0180064 protein O-linked glycosylation via xylose http://purl.obolibrary.org/obo/GO_0006493 protein O-linked glycosylation A glycoprotein biosynthetic process starting with the covalent linkage of a xylose via a beta-glycosidic bond to the oxygen atom of a serine or a threonine side chain in a protein, which can be further elongated with the sequential addition of sugar units resulting in the formation of a protein O-linked glycan. http://purl.obolibrary.org/obo/CL_4052061 epidermal keratinocyte http://purl.obolibrary.org/obo/CL_0000362 epidermal cell A keratinocyte of the skin epidermis that synthesizes keratin and undergoes successive stages of differentiation as it migrates from the basal layer to the cornified (stratum corneum) layer. These differentiation stages include the basal, spinous (prickle), and granular cell layers. This cell is central to epidermal homeostasis, mediating wound healing, immune modulation, including the secretion of cytokines and chemokines that recruit neutrophils (Simmons and Gallo, 2024), and intercellular communication with adjacent melanocytes (Marrapodi and Bellei, 2024). http://purl.obolibrary.org/obo/CL_4052058 Merkel cell of epidermis http://purl.obolibrary.org/obo/CL_0000362 epidermal cell A Merkel cell found mainly in the basal layer of the epidermis and the outer root sheath of hair follicles, particularly concentrated in areas with high tactile acuity, such as touch domes, hair follicles, and fingertips. http://purl.obolibrary.org/obo/UBERON_8600148 tooth surface structure http://purl.obolibrary.org/obo/UBERON_0003102 surface structure A surface structure that is part of a calcareous tooth. http://purl.obolibrary.org/obo/CL_4033097 Schlemm's canal endothelial cell http://purl.obolibrary.org/obo/CL_0002543 vein endothelial cell A specialised endothelial cell that is part of the canal of Schlemm. This cell type shares characteristics and expresses markers of both blood and lymphatic endothelial cells (Kizhatil et al., 2014) and regulates aqueous humor outflow resistance by modulating pore formation and responding to mechanical strain (Stamer et al., 2015). http://purl.obolibrary.org/obo/CL_4072001 newly formed oligodendrocyte http://purl.obolibrary.org/obo/CL_0000128 oligodendrocyte A post-mitotic oligodendrocyte that has exited the cell cycle and begun early stage differentiation. The cell begins to acquire oligodendrocyte-like characteristics but has not yet initiated myelination. In mice, NFOL is marked by the expression of Tcf7l2 and Cemip2 (also known as Tmem2), among other early myelin-related genes. These markers highlight cells transitioning from a precursor to a more differentiated, pre-myelinating state. http://purl.obolibrary.org/obo/CL_4300029 cerebellar glutamatergic neuron (Mmus) http://purl.obolibrary.org/obo/CL_2000028 cerebellum glutamatergic neuron A cerebellum glutamatergic neuron of the Mus musculus brain. Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Class:29 CB Glut. http://purl.obolibrary.org/obo/CL_4300031 OPC-Oligo cell (Mmus) http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell A cell of the Mus musculus brain. Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Class:31 OPC-Oligo. http://purl.obolibrary.org/obo/CL_4300359 astrocyte of cerebrum (Mmus) http://purl.obolibrary.org/obo/CL_0000127 astrocyte A transcritpomically defined type of astrocytes primarily restricted to the dorsal regions of the cerebrum. It is distinguished from other cells in the brain by selective expression of Gja1 (Mmus), Lhx2 (Mmus), Gpc5 (Mmus), Nr2f1 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Subclass:319 Astro-TE NN. http://purl.obolibrary.org/obo/CL_4300362 tanycyte (Mmus) http://purl.obolibrary.org/obo/CL_0002085 tanycyte A tanycyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gpr50 (Mmus), Apoe (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Subclass:322 Tanycyte NN. http://purl.obolibrary.org/obo/CL_4300363 ependymal cell (Mmus) http://purl.obolibrary.org/obo/CL_0000065 ependymal cell A ependymal cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Tmem212 (Mmus), Rarres2 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Subclass:323 Ependymal NN. http://purl.obolibrary.org/obo/CL_4300367 oligodendrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4300031 OPC-Oligo cell (Mmus) A oligodendrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Cldn11 (Mmus), Gjc3 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Subclass:327 Oligo NN. http://purl.obolibrary.org/obo/CL_4300370 VLMC NN vascular leptomeningeal cell (Mmus) http://purl.obolibrary.org/obo/CL_4023051 vascular leptomeningeal cell A vascular leptomeningeal cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Apod (Mmus), Slc6a13 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Subclass:330 VLMC NN. http://purl.obolibrary.org/obo/CL_4301573 DCO Il22 Gly-Gaba_3 cerebellar neuron (Mmus) http://purl.obolibrary.org/obo/CL_4300348 DCO Il22 Gly-Gaba cerebellar neuron (Mmus) A cerebellar neuron of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Fat2 (Mmus), Slc6a5 (Mmus), Cgnl1 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1143 DCO Il22 Gly-Gaba_3. http://purl.obolibrary.org/obo/CL_4301576 CB PLI Gly-Gaba_3 Purkinje layer interneuron (Mmus) http://purl.obolibrary.org/obo/CL_4300349 Purkinje layer interneuron (Mmus) A Purkinje layer interneuron of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Pax2 (Mmus), C1ql3 (Mmus), Tfap2b (Mmus), Gabrb1 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1146 CB PLI Gly-Gaba_3. http://purl.obolibrary.org/obo/CL_4301578 cerebellar Golgi cell (Mmus) http://purl.obolibrary.org/obo/CL_4300028 cerebellar GABAergic neuron (Mmus) A cerebellar Golgi cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Zfp385c (Mmus), Tfap2b (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1148 CBX Golgi Gly-Gaba_1. http://purl.obolibrary.org/obo/CL_4301580 CBX MLI Megf11 Gaba_2 molecular layer interneuron (Mmus) http://purl.obolibrary.org/obo/CL_4300351 CBX MLI Megf11 Gaba molecular layer interneuron (Mmus) A molecular layer interneuron of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gabra6 (Mmus), Pvalb (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1150 CBX MLI Megf11 Gaba_2. http://purl.obolibrary.org/obo/CL_4301583 CBX Purkinje Gaba_2 Purkinje cell (Mmus) http://purl.obolibrary.org/obo/CL_4300353 Purkinje cell (Mmus) A Purkinje cell of the Mus musculus brain. Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1153 CBX Purkinje Gaba_2. http://purl.obolibrary.org/obo/CL_4301586 unipolar brush cell (Mmus) http://purl.obolibrary.org/obo/CL_4300029 cerebellar glutamatergic neuron (Mmus) A unipolar brush cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Sln (Mmus), Lmx1a (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1156 DCO UBC Glut_1. http://purl.obolibrary.org/obo/CL_4301593 Astro-TE NN_3 astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4300359 astrocyte of cerebrum (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gja1 (Mmus), Grin2c (Mmus), Dcc (Mmus), Slc7a10 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1163 Astro-TE NN_3. http://purl.obolibrary.org/obo/CL_4301595 Astro-TE NN_5 astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4300359 astrocyte of cerebrum (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gja1 (Mmus), Thbs4 (Mmus), Kcnk10 (Mmus), Pak1 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1165 Astro-TE NN_5. http://purl.obolibrary.org/obo/CL_4301597 Astro-OLF NN_2 astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4300360 olfactory areas astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gja1 (Mmus), Hs3st3a1 (Mmus), Slco1c1 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1167 Astro-OLF NN_2. http://purl.obolibrary.org/obo/CL_4301602 Tanycyte NN_1 tanycyte (Mmus) http://purl.obolibrary.org/obo/CL_4300362 tanycyte (Mmus) A tanycyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Cnmd (Mmus), Lpl (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1172 Tanycyte NN_1. http://purl.obolibrary.org/obo/CL_4301608 choroid plexus epithelial cell (Mmus) http://purl.obolibrary.org/obo/CL_0000706 choroid plexus epithelial cell A choroid plexus epithelial cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of 2900040C04Rik (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1178 CHOR NN_1. http://purl.obolibrary.org/obo/CL_4301612 newly formed oligodendrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4300367 oligodendrocyte (Mmus) A newly formed oligodendrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of 9630013A20Rik (Mmus), Ptprb (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1182 NFOL NN_2. http://purl.obolibrary.org/obo/CL_4301613 myelin-forming oligodendrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4300367 oligodendrocyte (Mmus) A myelin-forming oligodendrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Cldn11 (Mmus), Sec14l5 (Mmus), 9630013A20Rik (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1183 MFOL NN_3. http://purl.obolibrary.org/obo/CL_4301615 olfactory ensheathing cell (Mmus) http://purl.obolibrary.org/obo/CL_0011028 olfactory ensheathing cell A olfactory ensheathing cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Apod (Mmus), Npy (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1185 OEC NN_1. http://purl.obolibrary.org/obo/CL_4301616 arachnoid barrier cell (Mmus) http://purl.obolibrary.org/obo/CL_4023097 arachnoid barrier cell A arachnoid barrier cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Thbd (Mmus), Ccn3 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1186 ABC NN_1. http://purl.obolibrary.org/obo/CL_4307027 cerebellar astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_0002603 astrocyte of the cerebellum A transcriptomically defined type of astrocyte localized exclusively in the cerebellum beneath the Purkinje cell layer. It is distinguished from other cells in the brain by selective expression of Dao (Mmus), Efemp1 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5207 Astro-CB NN_1. http://purl.obolibrary.org/obo/CL_4307029 Astro-NT NN_1 Slc36a2 astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301589 Astro-NT NN_1 astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gfap (Mmus), Slc36a2 (Mmus), Sfrp5 (Mmus). It is distinguished from other Astro-NT NN_1 cells by expression of Slc36a2, Sfrp5. These cells are located in the Midbrain, Cerebellum, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5209 Astro-NT NN_1. http://purl.obolibrary.org/obo/CL_4307034 Astro-NT NN_2 Fzd2 astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301590 Astro-NT NN_2 astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gja1 (Mmus), A330076C08Rik (Mmus), Sfrp5 (Mmus), Gria2 (Mmus). It is distinguished from other Astro-NT NN_2 cells by expression of Fzd2, Gria2, Ttll3. These cells are located in the Midbrain, Thalamus, Pons , in or close to the regions: Midbrain reticular nucleus . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5214 Astro-NT NN_2. http://purl.obolibrary.org/obo/CL_4307038 Astro-TE NN_1 Myoc astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301591 Astro-TE NN_1 astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Myoc (Mmus), Lhx2 (Mmus), Kcne1l (Mmus), Alpk1 (Mmus). It is distinguished from other Astro-TE NN_1 cells by expression of Myoc, Kcne1l, Alpk1. These cells are located in the Isocortex, Olfactory areas, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5218 Astro-TE NN_1. http://purl.obolibrary.org/obo/CL_4307039 Astro-TE NN_1 Rasl10b astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301591 Astro-TE NN_1 astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gfap (Mmus), Ddn (Mmus), Myoc (Mmus), Rasl10b (Mmus). It is distinguished from other Astro-TE NN_1 cells by expression of Rasl10b, Igfbp5. These cells are located in the Hippocampal region, Isocortex, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5219 Astro-TE NN_1. http://purl.obolibrary.org/obo/CL_4307044 Astro-TE NN_3 Cxcl5 astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301593 Astro-TE NN_3 astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gja1 (Mmus), Cxcl5 (Mmus), Ddn (Mmus). It is distinguished from other Astro-TE NN_3 cells by expression of Cxcl5, Kif5a. These cells are located in the Hippocampal region, Isocortex, Olfactory areas, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5224 Astro-TE NN_3. http://purl.obolibrary.org/obo/CL_4307045 Astro-TE NN_3 Fam163a astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301593 Astro-TE NN_3 astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of S1pr1 (Mmus), Fam163a (Mmus), Kcnq3 (Mmus), Kcnq1ot1 (Mmus). It is distinguished from other Astro-TE NN_3 cells by expression of Fam163a, Nr2f1, Kcnq1ot1. These cells are located in the Isocortex, Olfactory areas . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5225 Astro-TE NN_3. http://purl.obolibrary.org/obo/CL_4307047 Astro-TE NN_3 Crym astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301593 Astro-TE NN_3 astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of S1pr1 (Mmus), Crym (Mmus), Grin2c (Mmus). It is distinguished from other Astro-TE NN_3 cells by expression of Crym, Gabbr2. These cells are located in the Striatum dorsal region, Striatum ventral region , in or close to the regions: Nucleus accumbens, Caudoputamen . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5227 Astro-TE NN_3. http://purl.obolibrary.org/obo/CL_4307048 Astro-TE NN_4 astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4300359 astrocyte of cerebrum (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of S1pr1 (Mmus), Thbs4 (Mmus), Gm29683 (Mmus), Slc39a12 (Mmus). It is distinguished from other Astro-TE NN cells by expression of Gm29683. These cells are located in the Cortical subplate, brain , in or close to the regions: Lateral amygdalar nucleus, external capsule . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5228 Astro-TE NN_4. http://purl.obolibrary.org/obo/CL_4307050 Astro-TE NN_5 Adamts18 astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301595 Astro-TE NN_5 astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of S1pr1 (Mmus), Adamts18 (Mmus), Crym (Mmus). It is distinguished from other Astro-TE NN_5 cells by expression of Adamts18. These cells are located in the Lateral septal complex, Striatum dorsal region, brain , in or close to the regions: Nucleus accumbens, Caudoputamen, lateral ventricle . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5230 Astro-TE NN_5. http://purl.obolibrary.org/obo/CL_4307054 Astro-OLF NN_2 Alk astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301597 Astro-OLF NN_2 astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of S1pr1 (Mmus), Chrdl1 (Mmus), Sfrp1 (Mmus), Atp13a4 (Mmus). It is distinguished from other Astro-OLF NN_2 cells by expression of Alk, Atp13a4. These cells are located in the Olfactory areas , in or close to the regions: Anterior olfactory nucleus, Main olfactory bulb, granule layer, Main olfactory bulb, mitral layer . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5234 Astro-OLF NN_2. http://purl.obolibrary.org/obo/CL_4307055 Astro-OLF NN_3 Ecrg4 astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301598 Astro-OLF NN_3 astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of C230072F16Rik (Mmus), Dipk1c (Mmus), Ecrg4 (Mmus). It is distinguished from other Astro-OLF NN_3 cells by expression of Ecrg4. These cells are located in the Olfactory areas , in or close to the regions: Main olfactory bulb, granule layer . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5235 Astro-OLF NN_3. http://purl.obolibrary.org/obo/CL_4307056 Astro-OLF NN_3 Sfrp1 astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301598 Astro-OLF NN_3 astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of S1pr1 (Mmus), 6530411M01Rik (Mmus), Sfrp1 (Mmus), Aqp4 (Mmus). It is distinguished from other Astro-OLF NN_3 cells by expression of Sfrp1, Aqp4. These cells are located in the Olfactory areas , in or close to the regions: Main olfactory bulb, granule layer, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5236 Astro-OLF NN_3. http://purl.obolibrary.org/obo/CL_4307063 Tanycyte NN_1 Cnmd tanycyte of subfornical organ (Mmus) http://purl.obolibrary.org/obo/CL_4301602 Tanycyte NN_1 tanycyte (Mmus) A tanycyte of subfornical organ of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Cnmd (Mmus), Sfta3-ps (Mmus). It is distinguished from other Tanycyte NN_1 cells by expression of Cnmd. These cells are located in the brain , in or close to the regions: choroid plexus, third ventricle . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5243 Tanycyte NN_1. http://purl.obolibrary.org/obo/CL_4307064 Tanycyte NN_1 Glp1r tanycyte (Mmus) http://purl.obolibrary.org/obo/CL_4301602 Tanycyte NN_1 tanycyte (Mmus) A tanycyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of C230072F16Rik (Mmus), Glp1r (Mmus). It is distinguished from other Tanycyte NN_1 cells by expression of Glp1r. These cells are located in the Hypothalamus, brain , in or close to the regions: Anteroventral periventricular nucleus . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5244 Tanycyte NN_1. http://purl.obolibrary.org/obo/CL_4307065 Tanycyte NN_2 Mylk3 alpha1-tanycyte (Mmus) http://purl.obolibrary.org/obo/CL_4301603 Tanycyte NN_2 tanycyte (Mmus) A alpha1-tanycyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Dynlrb2 (Mmus), Mylk3 (Mmus), Sfta3-ps (Mmus). It is distinguished from other Tanycyte NN_2 cells by expression of Mylk3. It is glutamatergic (inferred from expression of Slc17a8). These cells are located in the Hypothalamus , in or close to the regions: Periventricular hypothalamic nucleus, intermediate part . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5245 Tanycyte NN_2. http://purl.obolibrary.org/obo/CL_4307066 Tanycyte NN_2 Mroh5 alpha1-tanycyte (Mmus) http://purl.obolibrary.org/obo/CL_4301603 Tanycyte NN_2 tanycyte (Mmus) A alpha1-tanycyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Ccdc170 (Mmus), Nkx2-4 (Mmus), Dock8 (Mmus). It is distinguished from other Tanycyte NN_2 cells by expression of Mroh5. These cells are located in the Hypothalamus, brain , in or close to the regions: Periventricular hypothalamic nucleus, intermediate part, third ventricle, Arcuate hypothalamic nucleus . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5246 Tanycyte NN_2. http://purl.obolibrary.org/obo/CL_4307067 alpha2-tanycyte (Mmus) http://purl.obolibrary.org/obo/CL_4301603 Tanycyte NN_2 tanycyte (Mmus) A alpha2-tanycyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Pdzph1 (Mmus), Wdr63 (Mmus), Dscaml1 (Mmus), P3h2 (Mmus). It is distinguished from other Tanycyte NN_2 cells by expression of Dscaml1, P3h2. These cells are located in the Hypothalamus , in or close to the regions: Periventricular hypothalamic nucleus, posterior part, Arcuate hypothalamic nucleus . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5247 Tanycyte NN_2. http://purl.obolibrary.org/obo/CL_4307068 Tanycyte NN_2 Otx2 tanycyte (Mmus) http://purl.obolibrary.org/obo/CL_4301603 Tanycyte NN_2 tanycyte (Mmus) A tanycyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Ccdc146 (Mmus), Tbx3 (Mmus), Otx2 (Mmus). It is distinguished from other Tanycyte NN_2 cells by expression of Otx2, Nkx2-4. These cells are located in the Hypothalamus, brain , in or close to the regions: Periventricular hypothalamic nucleus, posterior part, third ventricle . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5248 Tanycyte NN_2. http://purl.obolibrary.org/obo/CL_4307070 beta-2 tanycyte (Mmus) http://purl.obolibrary.org/obo/CL_4300362 tanycyte (Mmus) A beta2-tanycyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Fndc3c1 (Mmus), Ecrg4 (Mmus). It is distinguished from other Tanycyte NN cells by expression of Ecrg4. These cells are located in the Hypothalamus, brain , in or close to the regions: Median eminence, third ventricle, Arcuate hypothalamic nucleus . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5250 Tanycyte NN_3. http://purl.obolibrary.org/obo/CL_4307087 OPC NN_1 Irx2 oligodendrocyte precursor cell (Mmus) http://purl.obolibrary.org/obo/CL_4300366 oligodendrocyte precursor cell (Mmus) A oligodendrocyte precursor cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Pdgfra (Mmus), Pclaf (Mmus), Irx2 (Mmus). It is distinguished from other OPC NN_1 cells by expression of Neil3, Irx2. These cells are located in the Cerebellum, brain, Midbrain, Pons, Medulla . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5267 OPC NN_1. http://purl.obolibrary.org/obo/CL_4307088 OPC NN_1 Mms22l oligodendrocyte precursor cell (Mmus) http://purl.obolibrary.org/obo/CL_4300366 oligodendrocyte precursor cell (Mmus) A oligodendrocyte precursor cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Pdgfra (Mmus), Olig1 (Mmus), Mms22l (Mmus), Top2a (Mmus). It is distinguished from other OPC NN_1 cells by expression of Mms22l, Foxg1, Top2a. These cells are located in the Isocortex, Olfactory areas, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5268 OPC NN_1. http://purl.obolibrary.org/obo/CL_4307089 OPC NN_1 Col27a1 oligodendrocyte precursor cell (Mmus) http://purl.obolibrary.org/obo/CL_4300366 oligodendrocyte precursor cell (Mmus) A oligodendrocyte precursor cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Pdgfra (Mmus), Olig1 (Mmus), Col27a1 (Mmus). It is distinguished from other OPC NN_1 cells by expression of Col27a1. These cells are located in the Midbrain, Pons, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5269 OPC NN_1. http://purl.obolibrary.org/obo/CL_4307092 COP NN_1 Rgcc committed oligodendrocyte precursor (Mmus) http://purl.obolibrary.org/obo/CL_4301611 commited oligodendrocyte precursor (Mmus) A committed oligodendrocyte precursor of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gpr17 (Mmus), Bmp4 (Mmus), Zfp36l1 (Mmus). It is distinguished from other COP NN_1 cells by expression of Rgcc, Plpp4. These cells are located in the Isocortex, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5272 COP NN_1. http://purl.obolibrary.org/obo/CL_4307093 COP NN_1 9130019P16Rik committed oligodendrocyte precursor (Mmus) http://purl.obolibrary.org/obo/CL_4301611 commited oligodendrocyte precursor (Mmus) A committed oligodendrocyte precursor of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gpr17 (Mmus), Gp1bb (Mmus), Pdzd2 (Mmus), Plekhg1 (Mmus). It is distinguished from other COP NN_1 cells by expression of Rgcc, 9130019P16Rik. These cells are located in the Isocortex, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5273 COP NN_1. http://purl.obolibrary.org/obo/CL_4307094 COP NN_1 C1ql1 committed oligodendrocyte precursor (Mmus) http://purl.obolibrary.org/obo/CL_4301611 commited oligodendrocyte precursor (Mmus) A committed oligodendrocyte precursor of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gpr17 (Mmus), Bgn (Mmus), Gstp1 (Mmus), C1ql1 (Mmus). It is distinguished from other COP NN_1 cells by expression of C1ql1, Gstp1. These cells are located in the brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5274 COP NN_1. http://purl.obolibrary.org/obo/CL_4307096 COP NN_1 Vwc2 committed oligodendrocyte precursor (Mmus) http://purl.obolibrary.org/obo/CL_4301611 commited oligodendrocyte precursor (Mmus) A committed oligodendrocyte precursor of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of 9630013A20Rik (Mmus), Rab32 (Mmus), Opalin (Mmus). It is distinguished from other COP NN_1 cells by expression of Vwc2, Opalin. These cells are located in the brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5276 COP NN_1. http://purl.obolibrary.org/obo/CL_4307098 NFOL NN_2 9630013A20Rik newly formed oligodendrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301612 newly formed oligodendrocyte (Mmus) A newly formed oligodendrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of 9630013A20Rik (Mmus), Grin2b (Mmus). It is distinguished from other NFOL NN_2 cells by expression of 9630013A20Rik, Grin2b. These cells are located in the Midbrain, Thalamus, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5278 NFOL NN_2. http://purl.obolibrary.org/obo/CL_4307099 NFOL NN_2 Dbx2 newly formed oligodendrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301612 newly formed oligodendrocyte (Mmus) A newly formed oligodendrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of 9630013A20Rik (Mmus), Dbx2 (Mmus), Rassf10 (Mmus). It is distinguished from other NFOL NN_2 cells by expression of Dbx2, Rassf10. These cells are located in the Isocortex, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5279 NFOL NN_2. http://purl.obolibrary.org/obo/CL_4307100 NFOL NN_2 Rgs16 newly formed oligodendrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301612 newly formed oligodendrocyte (Mmus) A newly formed oligodendrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of 9630013A20Rik (Mmus), Rgs16 (Mmus), Rhbdl2 (Mmus). It is distinguished from other NFOL NN_2 cells by expression of Rgs16, Rhbdl2. These cells are located in the Isocortex, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5280 NFOL NN_2. http://purl.obolibrary.org/obo/CL_4307101 NFOL NN_2 Il23a newly formed oligodendrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301612 newly formed oligodendrocyte (Mmus) A newly formed oligodendrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of 9630013A20Rik (Mmus), Piezo2 (Mmus), Ptprb (Mmus). It is distinguished from other NFOL NN_2 cells by expression of Il23a, Opalin, Ptprb. These cells are located in the Isocortex, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5281 NFOL NN_2. http://purl.obolibrary.org/obo/CL_4307102 MFOL NN_3 Cxcl12 myelin-forming oligodendrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301613 myelin-forming oligodendrocyte (Mmus) A myelin-forming oligodendrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Opalin (Mmus), Cxcl12 (Mmus), Efhd1 (Mmus). It is distinguished from other MFOL NN_3 cells by expression of Cxcl12, Efhd1. These cells are located in the Isocortex, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5282 MFOL NN_3. http://purl.obolibrary.org/obo/CL_4307103 MFOL NN_3 Il23a myelin-forming oligodendrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301613 myelin-forming oligodendrocyte (Mmus) A myelin-forming oligodendrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of 9630013A20Rik (Mmus), Ppp1r14a (Mmus), Mroh3 (Mmus). It is distinguished from other MFOL NN_3 cells by expression of Il23a, Ppp1r14a. These cells are located in the Midbrain, Isocortex, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5283 MFOL NN_3. http://purl.obolibrary.org/obo/CL_4307104 MOL NN_4 Plin3 mature myelinating oligodendrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301614 mature myelinating oligodendrocyte (Mmus) A mature myelinating oligodendrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Prr5l (Mmus), Hapln2 (Mmus), Enpp6 (Mmus), Grm7 (Mmus). It is distinguished from other MOL NN_4 cells by expression of Plin3, Grm7. These cells are located in the Medulla, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5284 MOL NN_4. http://purl.obolibrary.org/obo/CL_4307105 MOL NN_4 Spock3 mature myelinating oligodendrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301614 mature myelinating oligodendrocyte (Mmus) A mature myelinating oligodendrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Cldn11 (Mmus), A230001M10Rik (Mmus), Spock3 (Mmus), Rhoj (Mmus). It is distinguished from other MOL NN_4 cells by expression of Spock3, Rhoj. These cells are located in the Midbrain, Isocortex, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5285 MOL NN_4. http://purl.obolibrary.org/obo/CL_4307106 MOL NN_4 Art3 mature myelinating oligodendrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301614 mature myelinating oligodendrocyte (Mmus) A mature myelinating oligodendrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Apod (Mmus), Klk6 (Mmus), Dlc1 (Mmus). It is distinguished from other MOL NN_4 cells by expression of Art3. These cells are located in the Medulla, Pons, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5286 MOL NN_4. http://purl.obolibrary.org/obo/CL_4307107 MOL NN_4 Il33 mature myelinating oligodendrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301614 mature myelinating oligodendrocyte (Mmus) A mature myelinating oligodendrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Opalin (Mmus), Grm3 (Mmus), Gm5087 (Mmus). It is distinguished from other MOL NN_4 cells by expression of Il33, Gm5087. These cells are located in the Isocortex, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5287 MOL NN_4. http://purl.obolibrary.org/obo/CL_4307108 MOL NN_4 Sspo mature myelinating oligodendrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301614 mature myelinating oligodendrocyte (Mmus) A mature myelinating oligodendrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Mog (Mmus), Anln (Mmus), Gm32633 (Mmus). It is distinguished from other MOL NN_4 cells by expression of Sspo, Selenop. These cells are located in the Isocortex, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5288 MOL NN_4. http://purl.obolibrary.org/obo/CL_4307111 OEC NN_1 A330076C08Rik olfactory ensheathing cell (Mmus) http://purl.obolibrary.org/obo/CL_4301615 olfactory ensheathing cell (Mmus) A olfactory ensheathing cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Apod (Mmus), Mybpc1 (Mmus), Syk (Mmus). It is distinguished from other OEC cells by expression of A330076C08Rik. These cells are located in the Olfactory areas, brain , in or close to the regions: olfactory nerve layer of main olfactory bulb, Main olfactory bulb . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5291 OEC NN_1. http://purl.obolibrary.org/obo/CL_4307112 OEC NN_1 Rasgef1c olfactory ensheathing cell (Mmus) http://purl.obolibrary.org/obo/CL_4301615 olfactory ensheathing cell (Mmus) A olfactory ensheathing cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Apod (Mmus), Mybpc1 (Mmus), Rasgef1c (Mmus). It is distinguished from other OEC cells by expression of Rasgef1c. It is glutamatergic (inferred from expression of Slc17a7). These cells are located in the brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5292 OEC NN_1. http://purl.obolibrary.org/obo/CL_4307115 ABC NN_1 Cubn arachnoid barrier cell (Mmus) http://purl.obolibrary.org/obo/CL_4301616 arachnoid barrier cell (Mmus) A arachnoid barrier cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Prg4 (Mmus), Cubn (Mmus). It is distinguished from other ABC NN cells by expression of Cubn. These cells are located in the brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5295 ABC NN_1. http://purl.obolibrary.org/obo/CL_4307132 microglial cell (Mmus) http://purl.obolibrary.org/obo/CL_0000129 microglial cell A microglial cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of C1qa (Mmus), Tmem119 (Mmus). It is distinguished from other Immune cells by expression of C1qa, Tmem119. These cells are located in the Isocortex, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5312 Microglia NN_1. http://purl.obolibrary.org/obo/GO_0110095 cellular detoxification of aldehyde http://purl.obolibrary.org/obo/GO_1990748 cellular detoxification Any process carried out at the cellular level that reduces or removes the toxicity of an aldehyde. These may include transport of aldehydes away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance. http://purl.obolibrary.org/obo/GO_0150098 glial cell-neuron signaling http://purl.obolibrary.org/obo/GO_0007267 cell-cell signaling Cell-cell signaling that mediates the transfer of information from a glial cell to a neuron. This signaling has been shown to be mediated by various molecules, depending on which glial cells release them, and in which tissues the signaling occurs, e.g. microglial cell-derived nerve growth factor (NGF) in the retina, or microglial cell-derived superoxide ions in the cerebellum. http://purl.obolibrary.org/obo/UBERON_0036295 renal pelvis/ureter http://purl.obolibrary.org/obo/UBERON_0000477 anatomical cluster The upper tract of the renal system. The renal pelvis is the large cavity in the middle of each kidney. Urine drains from each kidney through a long tube called the ureter, into the bladder, where it is stored until it is passed from the body through the urethra. http://purl.obolibrary.org/obo/GO_0140353 lipid export from cell http://purl.obolibrary.org/obo/GO_0006869 lipid transport The directed movement of a lipid from a cell, into the extracellular region. http://purl.obolibrary.org/obo/GO_0150115 cell-substrate junction organization http://purl.obolibrary.org/obo/GO_0034330 cell junction organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell-substrate junction. A cell-substrate junction is a specialized region of connection between a cell and the extracellular matrix. http://purl.obolibrary.org/obo/GO_0062171 lutein biosynthetic process http://purl.obolibrary.org/obo/GO_0016123 xanthophyll biosynthetic process The chemical reactions and pathways resulting in the formation of lutein. http://purl.obolibrary.org/obo/GO_0062172 lutein catabolic process http://purl.obolibrary.org/obo/GO_0016124 xanthophyll catabolic process The chemical reactions and pathways resulting in the breakdown of lutein. http://purl.obolibrary.org/obo/GO_0062177 radial spoke assembly http://purl.obolibrary.org/obo/GO_0065003 protein-containing complex assembly The aggregation, arrangement and bonding together of a set of components to form the radial spoke, a protein complex that links the outer microtubule doublet of the ciliary or flagellum axoneme with the sheath that surrounds the central pair of microtubules. http://purl.obolibrary.org/obo/GO_0150116 regulation of cell-substrate junction organization http://purl.obolibrary.org/obo/GO_0051128 regulation of cellular component organization Any process that modulates the frequency, rate or extent of cell-substrate junction organization. http://purl.obolibrary.org/obo/GO_0062247 chloroplast vesicle http://purl.obolibrary.org/obo/GO_0031410 cytoplasmic vesicle A intracellular vesicle that is part of a chloroplast. http://purl.obolibrary.org/obo/CL_0008037 gamma motor neuron http://purl.obolibrary.org/obo/CL_0008039 lower motor neuron A lower motor neuron that innervates only intrafusal muscle fibers. Unlike the alpha motor neurons, gamma motor neurons do not directly adjust the lengthening or shortening of muscles but function in adjusting the sensitivity of muscle spindles and in keeping muscle spindles taut, thereby allowing the continued firing of alpha neurons. http://purl.obolibrary.org/obo/CL_0009009 paneth cell of colon http://purl.obolibrary.org/obo/CL_1001588 colon glandular cell A paneth cell that is located in the epithelium of the colon. http://purl.obolibrary.org/obo/CL_0009010 transit amplifying cell http://purl.obolibrary.org/obo/CL_0000000 cell Transit-amplifying cells (TACs) are an undifferentiated population in transition between stem cells and differentiated cells. http://purl.obolibrary.org/obo/CL_0009011 transit amplifying cell of colon http://purl.obolibrary.org/obo/CL_0002253 epithelial cell of large intestine A rapidly proliferating population of cells that differentiate from stem cells of the intestinal crypt of the colon. Stem cells located in the crypts of Lieberkühn give rise to proliferating progenitor or transit amplifying cells that differentiate into the four major epithelial cell types. These include columnar absorptive cells or enterocytes, mucous secreting goblet cells, enteroendocrine cells and paneth cells. http://purl.obolibrary.org/obo/CL_0009012 transit amplifying cell of small intestine http://purl.obolibrary.org/obo/CL_0002254 epithelial cell of small intestine A rapidly proliferating population of cells that differentiate from stem cells of the intestinal crypt of the small intestine. Stem cells located in the crypts of Lieberkühn give rise to proliferating progenitor or transit amplifying cells that differentiate into the four major epithelial cell types. These include columnar absorptive cells or enterocytes, mucous secreting goblet cells, enteroendocrine cells and paneth cells. http://purl.obolibrary.org/obo/CL_0009014 Peyer's patch lymphocyte http://purl.obolibrary.org/obo/CL_0000542 lymphocyte A lymphocyte that is part of a Peyer's patch. These cells have a major role in driving the immune response to antigens sampled from the intestinal lumen, and in regulating the formation of follicle-associated epithelium and M cells in Peyer's patches by converting intestitial enterocytes into M cells. http://purl.obolibrary.org/obo/CL_0009015 Peyer's patch follicular dendritic cell http://purl.obolibrary.org/obo/CL_0000442 follicular dendritic cell A follicular dendritic cell located in the Peyer's patch. These cells from a meshwork in which Peyer's patch B cells reside. http://purl.obolibrary.org/obo/CL_0009016 intestinal crypt stem cell of large intestine http://purl.obolibrary.org/obo/CL_0002253 epithelial cell of large intestine An intestinal stem cell that is located in the large intestine crypt of Liberkuhn. These stem cells reside at the bottom of crypts in the large intestine and are highly proliferative. They either differentiate into transit amplifying cells or self-renew to form new stem cells. http://purl.obolibrary.org/obo/CL_0009017 intestinal crypt stem cell of small intestine http://purl.obolibrary.org/obo/CL_0002254 epithelial cell of small intestine An intestinal stem cell that is located in the small intestine crypt of Liberkuhn. These stem cells reside at the bottom of crypts in the small intestine and are highly proliferative. They either differentiate into transit amplifying cells or self-renew to form new stem cells. http://purl.obolibrary.org/obo/CL_0009018 lymphocyte of large intestine lamina propria http://purl.obolibrary.org/obo/CL_0000542 lymphocyte A lymphocyte that resides in the lamina propria of the large intestine. http://purl.obolibrary.org/obo/CL_0009019 nephrogenic zone cell http://purl.obolibrary.org/obo/CL_0002681 kidney cortical cell A kidney cortical cell that is part of the nephrogenic zone. http://purl.obolibrary.org/obo/CL_0010017 zygote http://purl.obolibrary.org/obo/CL_0000000 cell A zygote in a plant or an animal. http://purl.obolibrary.org/obo/CL_0011027 skeletal muscle fibroblast http://purl.obolibrary.org/obo/CL_1001609 muscle fibroblast Any fibroblast that is part of skeletal muscle tissue. http://purl.obolibrary.org/obo/CL_0011028 olfactory ensheathing cell http://purl.obolibrary.org/obo/CL_0000125 glial cell A neural-crest derived glial cell that supports the growth and survival of primary olfactory neuroons from the neuroepithelium in the nasal cavity to the brain by encasing large bundles of numerous unmyelinated axons. http://purl.obolibrary.org/obo/CL_0019020 extrahepatic cholangiocyte http://purl.obolibrary.org/obo/CL_1000488 cholangiocyte An epithelial cell of the extrahepatic bile ducts, including the left and right hepatic duct, common hepatic duct, and common bile duct. They are columnar in shape, and have a large nuclear-to-cytoplasmic ratio relative to small/intrahepatic cholangiocytes. http://purl.obolibrary.org/obo/CL_0019021 endothelial cell of periportal hepatic sinusoid http://purl.obolibrary.org/obo/CL_1000398 endothelial cell of hepatic sinusoid An endothelial cell found in the periportal region hepatic sinusoid, near the portal triad. The fenestrae of these cells are larger but fewer in number compared with those of endothelial cells near the centrilobular region of the hepatic sinusoid. http://purl.obolibrary.org/obo/CL_0019022 endothelial cell of pericentral hepatic sinusoid http://purl.obolibrary.org/obo/CL_1000398 endothelial cell of hepatic sinusoid An endothelial cell found in the centrilobular region hepatic sinusoid, near the central vein. The fenestrae of these cells are smaller but more numerous compared with those of endothelial cells near the periportal region of the hepatic sinusoid. http://purl.obolibrary.org/obo/CL_0019026 periportal region hepatocyte http://purl.obolibrary.org/obo/CL_0000182 hepatocyte Any hepatocyte that is part of the liver lobule periportal region. These cells are primarily involved in oxidative energy metabolism. http://purl.obolibrary.org/obo/CL_0019028 midzonal region hepatocyte http://purl.obolibrary.org/obo/CL_0000182 hepatocyte Any hepatocyte that is part of the liver lobule midzonal region. These cells have mixed functionality in comparison with those in the other two regions of the liver lobule. http://purl.obolibrary.org/obo/CL_0019029 centrilobular region hepatocyte http://purl.obolibrary.org/obo/CL_0000182 hepatocyte Any hepatocyte that is part of the liver lobule centrilobular region. These cells are the primary location for the biotransformation of drugs. http://purl.obolibrary.org/obo/CL_4006000 fibroblast of breast http://purl.obolibrary.org/obo/CL_0000057 fibroblast A fibroblast that is part of the breast. http://purl.obolibrary.org/obo/CL_4006001 fibroblast of skin of scalp http://purl.obolibrary.org/obo/CL_0002620 skin fibroblast A fibroblast that is part of the skin of scalp. http://purl.obolibrary.org/obo/CL_4023000 beta motor neuron http://purl.obolibrary.org/obo/CL_0008039 lower motor neuron A motor neuron that innervates both intrafusal and extrafusal muscle fibers. Low abundancy. They control both muscle contraction and responsiveness of the sensory feedback from muscle spindles. http://purl.obolibrary.org/obo/CL_4023001 static beta motor neuron http://purl.obolibrary.org/obo/CL_4023000 beta motor neuron A beta motor neuron that innervates nuclear chain fibers. http://purl.obolibrary.org/obo/CL_4023002 dynamic beta motor neuron http://purl.obolibrary.org/obo/CL_4023000 beta motor neuron A beta motor neuron that innervates the nuclear bag fibers of muscle spindles. http://purl.obolibrary.org/obo/CL_4023003 nuclear chain fiber http://purl.obolibrary.org/obo/CL_0008047 intrafusal muscle fiber A type of intrafusal muscle fiber that has nuclei arranged in a linear row. Unlike nuclear bag fibers, the equatorial region of these fibers (in the centre of the spindle) is not expanded. These fibers are responsible for the detection of changes in muscle length. They are innervated by static gamma motor neurons and are principally associated with type II sensory fibers. http://purl.obolibrary.org/obo/CL_4023004 nuclear bag fiber http://purl.obolibrary.org/obo/CL_0008047 intrafusal muscle fiber A type of intrafusal muscle fiber that lies in the center of a muscle spindle. Nuclei are clustered centrally and give the equatorial region a swollen appearance. They are associated with associated with dynamic gamma motor neurons, and the stretching of the equatorial region of the nuclear bag fibers results in an increase in the firing rate of type Ia sensory fibers. http://purl.obolibrary.org/obo/CL_4023005 dynamic nuclear bag fiber http://purl.obolibrary.org/obo/CL_4023004 nuclear bag fiber A nuclear bag fiber that is sensitive mainly to the rate of change in muscle length. http://purl.obolibrary.org/obo/CL_4023006 static nuclear bag fiber http://purl.obolibrary.org/obo/CL_4023004 nuclear bag fiber A nuclear bag fiber that is sensitive only changes in muscle length but not the rate of that change. http://purl.obolibrary.org/obo/UBERON_8410024 intestinal junction http://purl.obolibrary.org/obo/UBERON_1100000 digestive tract junction An anatomical junction between two parts of the intestine. http://purl.obolibrary.org/obo/UBERON_1100000 digestive tract junction http://purl.obolibrary.org/obo/UBERON_0007651 anatomical junction An anatomical junction between two parts of the digestive tract. http://purl.obolibrary.org/obo/CL_4023055 corticothalamic VAL/VM projecting glutamatergic neuron of the primary motor cortex http://purl.obolibrary.org/obo/CL_2000049 primary motor cortex pyramidal cell A corticothalamic-projecting glutamatergic neuron that is located in L6 and lower L5 of the primary motor cortex, with a pyramidal morphology and mostly untufted apical dendrites terminating in midcortical layers. CT VAL/VM (ventroanterior-ventrolateral complex/ventromedial nucleus) cells have a near tonic firing pattern and are distinguished from L6 IT neurons by a lower inter-spike interval adaptation index. http://purl.obolibrary.org/obo/GO_0140650 radial glia-guided pyramidal neuron migration http://purl.obolibrary.org/obo/GO_0001764 neuron migration The radial migration of a pyramidal neuron along radial glial cells. http://purl.obolibrary.org/obo/CL_0009032 B cell of appendix http://purl.obolibrary.org/obo/CL_0000236 B cell A B cell that is located in a vermiform appendix. http://purl.obolibrary.org/obo/CL_4023077 bitufted neuron http://purl.obolibrary.org/obo/CL_0000099 interneuron A type of interneuron that has two clusters of dendritic branches that originate directly from the soma and extend in opposite directions and axons that form a plexus which spreads widely. Compared to bipolar neurons, bitufted neurons have branching that occur close to the soma. http://purl.obolibrary.org/obo/CL_4023081 inverted L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (Mmus) http://purl.obolibrary.org/obo/CL_4023092 inverted pyramidal neuron a L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex that has inverted pyramidal morphology. http://purl.obolibrary.org/obo/CL_4023043 L5/6 near-projecting glutamatergic neuron of the primary motor cortex http://purl.obolibrary.org/obo/CL_4030067 L5/6 near-projecting glutamatergic neuron A transcriptomically distinct near-projecting glutamatergic neuron with a soma found in layer 5/6 of the primary motor cortex. The standard transcriptomic reference data for this cell type can be found on the CellxGene census under the collection: 'Transcriptomic cytoarchitecture reveals principles of human neocortex organization', dataset: 'Supercluster: Deep layer (non-IT) excitatory neurons', Author Categories: 'CrossArea_subclass', cluster L5/6 NP. http://purl.obolibrary.org/obo/CL_4023092 inverted pyramidal neuron http://purl.obolibrary.org/obo/CL_0000598 pyramidal neuron A pyramidal neuron which has an apical tree which is oriented towards the white matter. http://purl.obolibrary.org/obo/CL_4023066 horizontal pyramidal neuron http://purl.obolibrary.org/obo/CL_0000598 pyramidal neuron A pyramidal neuron which has an apical tree which is oriented parallel to the pia. This is unlike typical pyramidal neurons which have its apical dendrite aligned vertically. http://purl.obolibrary.org/obo/CL_0009052 smooth muscle cell of anorectum http://purl.obolibrary.org/obo/CL_1000279 smooth muscle cell of large intestine A smooth muscle cell that is located in the anorectum. http://purl.obolibrary.org/obo/CL_0009054 microfold cell of epithelium proper of anorectum http://purl.obolibrary.org/obo/CL_1000360 microfold cell of epithelium proper of large intestine A microfold cell (M cell) that is part of the anorectum. http://purl.obolibrary.org/obo/CL_0009059 plasma cell of medullary sinus of lymph node http://purl.obolibrary.org/obo/CL_0000786 plasma cell A plasma cell that is located in the medullary sinus of the lymph node. http://purl.obolibrary.org/obo/CL_0009061 intestinal crypt stem cell of anorectum http://purl.obolibrary.org/obo/CL_0009016 intestinal crypt stem cell of large intestine An intestinal crypt stem cell that is located in the anorectum. http://purl.obolibrary.org/obo/CL_0009111 centrocyte http://purl.obolibrary.org/obo/CL_0000844 germinal center B cell A germinal center B cell found in a lymph node germinal center light zone. http://purl.obolibrary.org/obo/CL_0017009 Axl+ dendritic cell, human http://purl.obolibrary.org/obo/CL_0001056 dendritic cell, human A human dendritic cell that expresses the AXL and SIGLEC6 genes. http://purl.obolibrary.org/obo/CL_0003025 retinal ganglion cell C3 http://purl.obolibrary.org/obo/CL_0003024 retinal ganglion cell C inner A retinal ganglion cell C inner that has sparse dendritic density, and large dendritic field. http://purl.obolibrary.org/obo/CL_0003038 M7-OFF retinal ganglion cell http://purl.obolibrary.org/obo/CL_4023033 OFF retinal ganglion cell An M7 retinal ganglion cells with synaptic terminals in S2 and is depolarized by decreased illumination of their receptive field center http://purl.obolibrary.org/obo/CL_0004246 monostratified cell http://purl.obolibrary.org/obo/CL_2000029 central nervous system neuron A central nervous system neuron that stratifies at one and only one location. http://purl.obolibrary.org/obo/CL_0003033 M4 retinal ganglion cell http://purl.obolibrary.org/obo/CL_0000740 retinal ganglion cell A monostratified retinal ganglion cell that has a large soma, a medium dendritic field with post synaptic terminals in sublaminar layer S3. http://purl.obolibrary.org/obo/CL_0004230 diffuse bistratified amacrine cell http://purl.obolibrary.org/obo/CL_0004251 narrow field retinal amacrine cell A bistratified amacrine cell with a small dendritic field that has post-synaptic terminals in S1 and the border of S1-S2, and termination of a second arbor within the border of S2-S3 and S3. http://purl.obolibrary.org/obo/UBERON_8480024 skin of sacral region http://purl.obolibrary.org/obo/UBERON_0001415 skin of pelvis A zone of skin that is part of the sacral region. http://purl.obolibrary.org/obo/CL_4030034 respiratory tract multiciliated cell http://purl.obolibrary.org/obo/CL_0005012 multiciliated epithelial cell A multiciliated epithelial cell located in the respiratory tract epithelium, characterized by a columnar shape and motile cilia on its apical surface. This cell develops through a highly orchestrated process, transitioning from a basal progenitor via an intermediate deuterosomal cell stage that generates centrioles essential for ciliogenesis. http://purl.obolibrary.org/obo/CL_4030035 dental pulp stem cell http://purl.obolibrary.org/obo/CL_0002148 dental pulp cell A dental pulp cell that possesses stem-cell-like qualities, including self-renewal capability and multi-lineage differentiation. http://purl.obolibrary.org/obo/CL_4030036 early spermatid http://purl.obolibrary.org/obo/CL_0000018 spermatid A spermatid in an early stage of maturation that has a round morphology and is transcriptionally active. http://purl.obolibrary.org/obo/CL_4030037 late spermatid http://purl.obolibrary.org/obo/CL_0000018 spermatid A spermatid in a late stage of maturation that has an elongated morphology and is transcriptionally inert when the acrosome is fully developed. http://purl.obolibrary.org/obo/CL_4030040 endometrial multiciliated epithelial cell http://purl.obolibrary.org/obo/CL_0005012 multiciliated epithelial cell A multi-ciliated cell of the endometrial epithelium. This cell is characterized by the presence of 9+2 motile cilia on its apical surface, which facilitates the movement of mucus across the endometrial surface. http://purl.obolibrary.org/obo/CL_4030041 luminal endometrial multiciliated epithelial cell http://purl.obolibrary.org/obo/CL_4030040 endometrial multiciliated epithelial cell A ciliated cell of the endometrial luminal epithelium. This cell is characterized by the presence of motile cilia on its apical surface. http://purl.obolibrary.org/obo/CL_4030042 glandular endometrial multiciliated epithelial cell http://purl.obolibrary.org/obo/CL_0009084 glandular epithelial cell of endometrium A ciliated cell of the endometrial glandular epithelium. This cell is characterized by the presence of motile cilia on its apical surface. http://purl.obolibrary.org/obo/CL_4033003 myoepithelial cell of bronchus submucosal gland http://purl.obolibrary.org/obo/CL_0002328 bronchial epithelial cell A(n) myoepithelial cell that is part of a(n) bronchus submucosal gland. http://purl.obolibrary.org/obo/CL_4033004 smooth muscle cell of taenia coli http://purl.obolibrary.org/obo/CL_1000279 smooth muscle cell of large intestine A(n) smooth muscle cell that is part of a(n) taenia coli. http://purl.obolibrary.org/obo/CL_4033005 serous secreting cell of bronchus submucosal gland http://purl.obolibrary.org/obo/CL_0019001 tracheobronchial serous cell A(n) serous secreting cell that is part of a(n) bronchus submucosal gland. http://purl.obolibrary.org/obo/CL_4033006 endothelial cell of efferent lymphatic vessel http://purl.obolibrary.org/obo/CL_0002138 endothelial cell of lymphatic vessel A(n) endothelial cell that is part of a(n) efferent lymphatic vessel. http://purl.obolibrary.org/obo/CL_4033007 brush cell of epithelium of lobar bronchus http://purl.obolibrary.org/obo/CL_0002208 brush cell of bronchus A(n) brush cell that is part of a(n) epithelium of lobar bronchus. http://purl.obolibrary.org/obo/CL_4033008 vein endothelial cell of respiratory system http://purl.obolibrary.org/obo/CL_0002543 vein endothelial cell A(n) vein endothelial cell that is part of a(n) respiratory system. http://purl.obolibrary.org/obo/CL_4033009 goblet cell of epithelium of lobar bronchus http://purl.obolibrary.org/obo/CL_1000312 bronchial goblet cell A(n) goblet cell that is part of a(n) epithelium of lobar bronchus. http://purl.obolibrary.org/obo/CL_4033010 neuroendocrine cell of epithelium of lobar bronchus http://purl.obolibrary.org/obo/CL_0008055 respiratory tract secretory epithelial cell A(n) neuroendocrine cell that is part of a(n) epithelium of lobar bronchus. http://purl.obolibrary.org/obo/CL_4033011 smooth muscle cell of large intestine smooth muscle circular layer http://purl.obolibrary.org/obo/CL_1000279 smooth muscle cell of large intestine A(n) smooth muscle cell that is part of a(n) large intestine smooth muscle circular layer. http://purl.obolibrary.org/obo/CL_4033012 smooth muscle cell of large intestine smooth muscle longitudinal layer http://purl.obolibrary.org/obo/CL_1000279 smooth muscle cell of large intestine A(n) smooth muscle cell that is part of a(n) large intestine smooth muscle longitudinal layer. http://purl.obolibrary.org/obo/CL_4033037 mucus secreting cell of tracheobronchial tree submucosal gland http://purl.obolibrary.org/obo/CL_0008055 respiratory tract secretory epithelial cell A mucus secreting cell of a submucosal gland of the tracheobronchial tree. http://purl.obolibrary.org/obo/CL_4030057 eccentric medium spiny neuron http://purl.obolibrary.org/obo/CL_1001474 medium spiny neuron A medium spiny neuron that exhibits transcriptional divergence from direct and indirect spiny projection neurons, for example, enrichment in Casz1, Otof, Cacng5 and Pcdh8 noted in mice. Whilst in general medium spiny neurons have been found to be differentially distributed across the basal ganglia, the eccentric medium spiny neuron cell type has been found to be more evenly distributed throughout cerebral nuclei. http://purl.obolibrary.org/obo/GO_0141188 nucleic acid catabolic process http://purl.obolibrary.org/obo/GO_0009057 macromolecule catabolic process The cellular DNA metabolic process resulting in the breakdown of a nucleic acid. http://purl.obolibrary.org/obo/GO_0170055 lipid transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity Enables the transfer of a lipid from one side of a membrane to the other. http://purl.obolibrary.org/obo/CL_4307091 OPC NN_2 oligodendrocyte precursor cell (Mmus) http://purl.obolibrary.org/obo/CL_4300366 oligodendrocyte precursor cell (Mmus) A oligodendrocyte precursor cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Pdgfra (Mmus), Cenpf (Mmus), Cenpa (Mmus). It is distinguished from other OPC NN cells by expression of Cenpa. These cells are located in the Isocortex, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5271 OPC NN_2. http://purl.obolibrary.org/obo/GO_0110053 regulation of actin filament organization http://purl.obolibrary.org/obo/GO_0032956 regulation of actin cytoskeleton organization Any process that modulates the frequency, rate or extent of actin filament organization. http://purl.obolibrary.org/obo/GO_0120116 glucagon processing http://purl.obolibrary.org/obo/GO_0016486 peptide hormone processing The formation of mature glucagon by proteolysis of the precursor proglucagon. http://purl.obolibrary.org/obo/PATO_0045021 normal flexibility http://purl.obolibrary.org/obo/PATO_0045001 normal object quality A flexibility which is relatively normal or average. http://purl.obolibrary.org/obo/PATO_0045081 normal viscosity http://purl.obolibrary.org/obo/PATO_0045001 normal object quality A viscosity which is relatively normal or average http://purl.obolibrary.org/obo/GO_0110088 hippocampal neuron apoptotic process http://purl.obolibrary.org/obo/GO_0051402 neuron apoptotic process Any apoptotic process that occurs in a hippocampal neuron. http://purl.obolibrary.org/obo/GO_0110089 regulation of hippocampal neuron apoptotic process http://purl.obolibrary.org/obo/GO_0043523 regulation of neuron apoptotic process Any process that modulates the occurrence or rate of cell death by apoptotic process in hippocampal neurons. http://purl.obolibrary.org/obo/GO_0110090 positive regulation of hippocampal neuron apoptotic process http://purl.obolibrary.org/obo/GO_0110089 regulation of hippocampal neuron apoptotic process Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process in hippocampal neurons. http://purl.obolibrary.org/obo/GO_0110091 negative regulation of hippocampal neuron apoptotic process http://purl.obolibrary.org/obo/GO_0110089 regulation of hippocampal neuron apoptotic process Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process in hippocampal neurons. http://purl.obolibrary.org/obo/PR_000036947 T-cell surface glycoprotein CD1 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A T-cell surface glycoprotein CD1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/GO_0062033 positive regulation of mitotic sister chromatid segregation http://purl.obolibrary.org/obo/GO_0033047 regulation of mitotic sister chromatid segregation Any process that starts or increases the frequency, rate or extent of sister chromatid segregation during mitosis. http://purl.obolibrary.org/obo/GO_0150044 regulation of postsynaptic dense core vesicle exocytosis http://purl.obolibrary.org/obo/GO_1905413 regulation of dense core granule exocytosis Any process that modulates the frequency, rate or extent of postsynaptic dense core vesicle exocytosis. http://purl.obolibrary.org/obo/GO_0150045 regulation of synaptic signaling by nitric oxide http://purl.obolibrary.org/obo/GO_0023051 regulation of signaling Any process that modulates the frequency, rate or extent of synaptic signaling by nitric oxide. http://purl.obolibrary.org/obo/GO_0062094 stomach development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the stomach over time, from its formation to the mature structure. The stomach is an expanded region of the vertebrate alimentary tract that serves as a food storage compartment and digestive organ. http://purl.obolibrary.org/obo/CL_3000000 ciliated epithelial cell of esophagus http://purl.obolibrary.org/obo/CL_0002252 epithelial cell of esophagus A ciliated epithelial cell of the esophagus. http://purl.obolibrary.org/obo/CL_3000001 Hofbauer cell http://purl.obolibrary.org/obo/CL_4033087 placental resident macrophage A tissue-resident macrophage that is part of the placenta. A Hofbauer cell expresses high levels of growth factors and metalloproteinases that support vasculogenesis, angiogenesis, branching morphogenesis and tissue remodeling. A Hofbauer cell has a fetal origin, is found in the villous stroma, chorion, and amnion, and is present throughout pregnancy. http://purl.obolibrary.org/obo/CL_3000002 sympathetic noradrenergic neuron http://purl.obolibrary.org/obo/CL_0008025 noradrenergic neuron Sympathetic noradrenergic neuron. http://purl.obolibrary.org/obo/CL_3000003 sympathetic cholinergic neuron http://purl.obolibrary.org/obo/CL_0011103 sympathetic neuron A type of autonomic neuron that releases acetylcholine. http://purl.obolibrary.org/obo/CL_3000004 peripheral sensory neuron http://purl.obolibrary.org/obo/CL_2000032 peripheral nervous system neuron A neuron type that is located in a peripheral nervous system and it transmits sensory information from the peripheral (PNS) to the central nervous system (CNS). A sensory neuron converts physical (light, sound, touch) or chemical (such as taste and smell) stimuli into an electrical signal through a process known as sensory transduction. The function of a sensory neuron is to carry informations from the external environment and internal body conditions to the central nervous system for further processing. http://purl.obolibrary.org/obo/UBERON_0037144 wall of heart http://purl.obolibrary.org/obo/UBERON_0000060 anatomical wall Wall of organ which has as its parts the endocardium, myocardium , epicardium, and the cardiac septum, surrounded by the pericardial sac proper and is continuous with the walls of the systemic and pulmonary arterial and venous trees. http://purl.obolibrary.org/obo/PATO_0070019 untufted pyramidal morphology http://purl.obolibrary.org/obo/PATO_0070017 standard pyramidal morphology A pyramidal cell morphology that inheres in neurons which lack a clear tuft formation but extend to large radial distances. http://purl.obolibrary.org/obo/PATO_0070012 bitufted cell morphology http://purl.obolibrary.org/obo/PATO_0070027 bitufted dendrite cell morphology A cell morphology that inheres in neurons which have two clusters of primary dendrites that originate directly and extend from opposite ends of the soma, and axons that form a plexus which spreads widely. Compared to the narrow vertical axonal projection of bipolar morphology, and the 'horse-tail' axonal cluster of double boquet cells, bitufted morphology has wide horizontal axonal spans, and branching that occur close to the soma. Their vertical projection is also less extensive and crosses mostly to neighboring layers. http://purl.obolibrary.org/obo/PATO_0010006 cell morphology http://purl.obolibrary.org/obo/PATO_0000051 morphology A quality of a single cell inhering in the bearer by virtue of the bearer's size or shape or structure. http://purl.obolibrary.org/obo/PATO_0070010 stellate morphology http://purl.obolibrary.org/obo/PATO_0070026 multipolar neuron morphology A cell morphology that inheres in neurons that have dendritic processes radiating from the cell body forming a star-like shape. http://purl.obolibrary.org/obo/CL_0009033 plasma cell of appendix http://purl.obolibrary.org/obo/CL_0000786 plasma cell A plasma cell that is located in a vermiform appendix. http://purl.obolibrary.org/obo/CL_0009036 appendix macrophage http://purl.obolibrary.org/obo/CL_0000235 macrophage A macrophage located in the vermiform appendix. http://purl.obolibrary.org/obo/CL_0009030 enteroendocrine cell of appendix http://purl.obolibrary.org/obo/CL_1001516 intestinal enteroendocrine cell An intestinal enteroendocrine cell that is located in a vermiform appendix. http://purl.obolibrary.org/obo/CL_4023054 mesothelial fibroblast http://purl.obolibrary.org/obo/CL_0000057 fibroblast A mesothelial cell that has undergone mesothelial-to-mesenchymal transition (MMT) to become a fibroblast cell. http://purl.obolibrary.org/obo/CL_4023048 L4/5 intratelencephalic projecting glutamatergic neuron of the primary motor cortex http://purl.obolibrary.org/obo/CL_4030062 L4/5 intratelencephalic projecting glutamatergic neuron An intratelencephalic-projecting glutamatergic with a soma located in upper L5 of the primary motor cortex. These cells have thin untufted apical dendrites. http://purl.obolibrary.org/obo/CL_0009013 fetal hepatobiliary progenitor cell http://purl.obolibrary.org/obo/CL_0011026 progenitor cell A progenitor cell with hepatic and biliary lineage potential, identified in mouse and human, and anatomically restricted to the ductal plate of fetal liver. http://purl.obolibrary.org/obo/CL_0009028 intestinal crypt stem cell of appendix http://purl.obolibrary.org/obo/CL_0009016 intestinal crypt stem cell of large intestine An intestinal crypt stem cell that is located in the vermiform appendix. These stem cells reside at the bottom of crypts in the appendix and are highly proliferative. They either differentiate into transit amplifying cells or self-renew to form new stem cells. http://purl.obolibrary.org/obo/CL_0009045 B cell of medullary sinus of lymph node http://purl.obolibrary.org/obo/CL_0000236 B cell A B cell found in the lymph node medullary sinus. http://purl.obolibrary.org/obo/CL_0009084 glandular epithelial cell of endometrium http://purl.obolibrary.org/obo/CL_0002149 epithelial cell of uterus An epithelial cell that is part of an endometrium glandular epithelium. http://purl.obolibrary.org/obo/CL_0009086 endothelial cell of respiratory system lymphatic vessel http://purl.obolibrary.org/obo/CL_0002138 endothelial cell of lymphatic vessel An endothelial cell that is part of a respiratory system lymphatic vessel. http://purl.obolibrary.org/obo/CL_0009087 fused extravillous trophoblast http://purl.obolibrary.org/obo/CL_0008036 extravillous trophoblast An extravillous trophoblast that is polynuclear. http://purl.obolibrary.org/obo/CL_0009092 endothelial cell of placenta http://purl.obolibrary.org/obo/CL_0000115 endothelial cell An endothelial cell that is part of a placenta. http://purl.obolibrary.org/obo/CL_0009093 smooth muscle cell of placenta http://purl.obolibrary.org/obo/CL_0000192 smooth muscle cell A smooth muscle cell that is part of a placenta. http://purl.obolibrary.org/obo/CL_0009094 endothelial cell of hepatic portal vein http://purl.obolibrary.org/obo/CL_0002543 vein endothelial cell An endothelial cell that is part of a hepatic portal vein. http://purl.obolibrary.org/obo/CL_0009095 endothelial cell of uterus http://purl.obolibrary.org/obo/CL_0000115 endothelial cell An endothelial cell that is part of a uterus. http://purl.obolibrary.org/obo/CL_4028003 alveolar capillary type 2 endothelial cell http://purl.obolibrary.org/obo/CL_4028001 pulmonary capillary endothelial cell An alveolar capillary endothelial cell that is located proximally to alveolar capillary type 1 endothelial cells and in close apposition to alveolar type 1 epithelial cells (also known as type I pneumocytes). http://purl.obolibrary.org/obo/CL_4028004 alveolar type 1 fibroblast cell http://purl.obolibrary.org/obo/CL_0002553 fibroblast of lung A pulmonary interstitial fibroblast that is part of the alveolus and contains lipid droplets. http://purl.obolibrary.org/obo/CL_4028006 alveolar adventitial fibroblast http://purl.obolibrary.org/obo/CL_0002553 fibroblast of lung A pulmonary interstitial fibroblast that is part of the alveolus and localizes to vascular adventitia. http://purl.obolibrary.org/obo/CL_4030001 stromal cell of thymus http://purl.obolibrary.org/obo/CL_0000499 stromal cell A stromal cell that is part of the thymus. http://purl.obolibrary.org/obo/CL_4029003 somatic nurse-like cell http://purl.obolibrary.org/obo/CL_4029001 gamete-nursing cell A gamete-nursing cell that derives from the somatic tissues of the gonad (del Pino, 2021). http://purl.obolibrary.org/obo/CL_4029001 gamete-nursing cell http://purl.obolibrary.org/obo/CL_0000000 cell A cell that supports the development of a gamete by providing it cytoplasmic material (including entire organelles) by direct cross-membrane channels (del Pino, 2021). http://purl.obolibrary.org/obo/UBERON_8440011 cortical visual area http://purl.obolibrary.org/obo/UBERON_0035014 functional part of brain The part of the cortex that is responsible for processing visual information. http://purl.obolibrary.org/obo/CL_0004225 spider amacrine cell http://purl.obolibrary.org/obo/CL_0004251 narrow field retinal amacrine cell A broadly stratifying amacrine cell with a small dendritic field, straight dendrites and post-synaptic terminals in S1, S2, and S3. http://purl.obolibrary.org/obo/CL_0004252 medium field retinal amacrine cell http://purl.obolibrary.org/obo/CL_0000561 amacrine cell An amicrine that has a medium dendritic field. http://purl.obolibrary.org/obo/CL_0003022 retinal ganglion cell C5 http://purl.obolibrary.org/obo/CL_0003020 retinal ganglion cell C outer A retinal ganglion cell C outer that has medium dendritic density and field size. http://purl.obolibrary.org/obo/CL_4023074 mammillary body neuron http://purl.obolibrary.org/obo/CL_0012001 neuron of the forebrain A neuron that has its soma located in the mammillary body. http://purl.obolibrary.org/obo/GO_0140979 intracellular nucleotide homeostasis http://purl.obolibrary.org/obo/GO_0055082 intracellular chemical homeostasis A homeostatic process involved in the maintenance of a steady state level of nucleotides within a cell. http://purl.obolibrary.org/obo/CL_4033040 lung resident memory CD8-positive, CD103-positive, alpha-beta T cell http://purl.obolibrary.org/obo/CL_4033039 lung resident memory CD8-positive, alpha-beta T cell A lung resident memory CD8-positive, alpha-beta T cell that is CD103-positive. http://purl.obolibrary.org/obo/CL_4033041 CCL3-positive alveolar macrophage http://purl.obolibrary.org/obo/CL_0000583 alveolar macrophage An alveolar macrophage that expresses CCL3. http://purl.obolibrary.org/obo/CL_4033042 metallothionein-positive alveolar macrophage http://purl.obolibrary.org/obo/CL_0000583 alveolar macrophage An alveolar macrophage that expresses metallothionein. http://purl.obolibrary.org/obo/CL_4033043 lung interstitial macrophage http://purl.obolibrary.org/obo/CL_1001603 lung macrophage A macrophage that is part of the lung connective tissue (pulmonary interstitium). This cell performs tissue remodeling and contributes to barrier immunity through antigen presentation. http://purl.obolibrary.org/obo/CL_4033044 deuterosomal cell http://purl.obolibrary.org/obo/CL_0002368 respiratory tract epithelial cell An epithelial cell part of respiratory tract epithelium that is a precursor of a multi-ciliated cell. This cell actively amplifies centrioles, a required step for multiciliogenesis. http://purl.obolibrary.org/obo/CL_4033045 lung migratory dendritic cell http://purl.obolibrary.org/obo/CL_0000451 dendritic cell A dendritic cell that captures antigens in a lung and migrates to a lymph node or to the spleen to activate T cells. http://purl.obolibrary.org/obo/CL_4033048 respiratory tract suprabasal cell http://purl.obolibrary.org/obo/CL_7770004 suprabasal cell A respiratory epithelial cell derived from a basal cell, with a topographic nuclear position between the basal and luminal cells of the airway epithelium. This non-basal, intermediate progenitor cell has limited proliferative capacity and can differentiate into multiciliated, secretory, or rare airway cells (ionocytes, tuft cells, neuroendocrine cells). It shares some ultrastructural features with basal cells but lacks the defined characteristics of fully differentiated cellular phenotypes. http://purl.obolibrary.org/obo/CL_4030058 TCR-positive macrophage http://purl.obolibrary.org/obo/CL_0000235 macrophage A macrophage that expresses the T cell receptor complex at the cell surface. http://purl.obolibrary.org/obo/CL_4030059 L2/3 intratelencephalic projecting glutamatergic neuron http://purl.obolibrary.org/obo/CL_4023040 L2/3-6 intratelencephalic projecting glutamatergic neuron A transcriptomically distinct intratelencephalic-projecting glutamatergic neuron with a soma found between cortical layer 2-4. This intratelencephalic-projecting glutamatergic neuron has thin-tufted apical dendrites and extends its axonal projection into L5 in the neocortex. This neuronal type has a hyperpolarised resting membrane potential. http://purl.obolibrary.org/obo/CL_4030060 L2 intratelencephalic projecting glutamatergic neuron http://purl.obolibrary.org/obo/CL_4023040 L2/3-6 intratelencephalic projecting glutamatergic neuron An intratelencephalic-projecting glutamatergic neuron with a soma found in cortical layer 2. http://purl.obolibrary.org/obo/CL_4030061 L3 intratelencephalic projecting glutamatergic neuron http://purl.obolibrary.org/obo/CL_4023040 L2/3-6 intratelencephalic projecting glutamatergic neuron An intratelencephalic-projecting glutamatergic neuron with a soma found in cortical layer 3. http://purl.obolibrary.org/obo/CL_4030062 L4/5 intratelencephalic projecting glutamatergic neuron http://purl.obolibrary.org/obo/CL_4023040 L2/3-6 intratelencephalic projecting glutamatergic neuron An intratelencephalic-projecting glutamatergic with a soma located in cortical layer 4/5. http://purl.obolibrary.org/obo/CL_4030063 L4 intratelencephalic projecting glutamatergic neuron http://purl.obolibrary.org/obo/CL_4023040 L2/3-6 intratelencephalic projecting glutamatergic neuron A transcriptomically distinct intratelencephalic-projecting glutamatergic neuron with a soma found in cortical layer 3-4. This neuron type can have a pyramidal, star-pyramidal or spiny stellate morphology and projects its output to L2/3 and L5A/B. http://purl.obolibrary.org/obo/CL_4030064 L5 intratelencephalic projecting glutamatergic neuron http://purl.obolibrary.org/obo/CL_4023040 L2/3-6 intratelencephalic projecting glutamatergic neuron An intratelencephalic-projecting glutamatergic neuron with a soma found in cortical layer 5. http://purl.obolibrary.org/obo/CL_4030065 L6 intratelencephalic projecting glutamatergic neuron http://purl.obolibrary.org/obo/CL_4023040 L2/3-6 intratelencephalic projecting glutamatergic neuron A transcriptomically distinct intratelencephalic-projecting glutamatergic neuron with a soma found in L6 of the primary motor cortex. These cells are short untufted pyramidal cells, which could be stellate or inverted. http://purl.obolibrary.org/obo/CL_4030066 ureteric bud cell http://purl.obolibrary.org/obo/CL_0002518 kidney epithelial cell An epithelial cell that is part of a ureteric bud. A ureteric bud cell has the potential to induce metanephric mesenchymal cells to proliferate and convert to epithelia that form renal tubules via: (1) the secretion of multiple diffusible growth factors that rescue renal progenitors from apoptosis and stimulate them to proliferate and (2) contact-dependent mechanisms that induce mesenchymal-epithelial conversion. http://purl.obolibrary.org/obo/CL_4033056 onychocyte http://purl.obolibrary.org/obo/CL_4052061 epidermal keratinocyte A terminally differentiated, specialized keratinocyte originating primarily from the nail matrix. During onychokeratinization, these cells undergo progressive flattening and produce high levels of hard, disulfide cross-linked keratins (Eckhart et al., 2024) that form the rigid, compact nail plate. Unlike epidermal keratinocytes, onychocytes are firmly integrated into the nail plate and do not desquamate. http://purl.obolibrary.org/obo/CL_4033057 luminal adaptive secretory precursor cell of mammary gland http://purl.obolibrary.org/obo/CL_0011026 progenitor cell A luminal epithelial cell of the mammary gland that can proliferate and has the potential to differentiate into a lactocyte during pregnancy. In humans, a luminal adaptive secretory precursor cell can be identified by high levels of the markers EpCAM and CD49f, and in mice it can be identified by low levels of CD29 and high levels of CD14, Kit, CD61, and Tspan8. http://purl.obolibrary.org/obo/CL_4033058 luminal hormone-sensing cell of mammary gland http://purl.obolibrary.org/obo/CL_0002326 luminal epithelial cell of mammary gland A luminal epithelial cell of the mammary gland that transduces endocrine cues to orchestrate proliferation, architectural remodeling, and differentiation of other cells in the mammary gland via paracrine signaling. This cell expresses high levels of estrogen receptors. In humans, a luminal hormone-sensing cell can be identified by high levels of EpCAM and low levels of CD49f, and in mice it can be identified by low levels of CD29 and high levels of Foxa1, CD133, and Sca1 (Ly6a). http://purl.obolibrary.org/obo/CL_4033059 lactocyte type 1 http://purl.obolibrary.org/obo/CL_0002325 lactocyte A lactocyte that highly expresses genes associated with transcription, immune cell function, and cellular stress. A lactocyte type 1 also expresses genes involved in milk component biosynthesis (e.g., LALBA and CSNs), albeit at lower levels than a lactocyte type 2. http://purl.obolibrary.org/obo/CL_4033060 lactocyte type 2 http://purl.obolibrary.org/obo/CL_0002325 lactocyte A lactocyte that highly expresses genes associated with lipid production and milk component biosynthesis. http://purl.obolibrary.org/obo/UBERON_8600024 pulmonary venule http://purl.obolibrary.org/obo/UBERON_0003512 lung blood vessel A venule that is part of a lung and drains oxygenated blood from pulmonary capillaries. A pulmonary venule merges into a pulmonary vein branch that runs in the pulmonary interlobular septa. http://purl.obolibrary.org/obo/GO_0160165 CD8-positive, alpha-beta T cell homeostasis http://purl.obolibrary.org/obo/GO_0043029 T cell homeostasis The process of regulating the proliferation and elimination of CD8-positive alpha-beta T cells such that the total number of CD8-positive alpha-beta T cells within a whole or part of an organism is stable over time in the absence of an outside stimulus. http://purl.obolibrary.org/obo/UBERON_8450003 embryonic craniocervical region http://purl.obolibrary.org/obo/UBERON_0007811 craniocervical region A craniocervical region that is part of an embryo. http://purl.obolibrary.org/obo/GO_0140139 solid phase of basement membrane http://purl.obolibrary.org/obo/GO_0030312 external encapsulating structure The solid compartment of the basement membrane ECM, including a specific subset of basement membrane collagens and basement membrane glycoproteins like laminins or nidogens. http://purl.obolibrary.org/obo/GO_0140143 collagenous component of basement membrane http://purl.obolibrary.org/obo/GO_0030312 external encapsulating structure Collagenous component of basement membrane ECMs, including collagen IV and other types of collagen specifically expressed in basement membrane. http://purl.obolibrary.org/obo/GO_0140149 non-collagenous component of interstitial matrix http://purl.obolibrary.org/obo/GO_0030312 external encapsulating structure The non-collagenous component of interstitial extracellular matrices, including glycoprotein like fibronectin and elastin. http://purl.obolibrary.org/obo/GO_0140151 solid phase of interstitial matrix http://purl.obolibrary.org/obo/GO_0030312 external encapsulating structure The solid compartment of the interstitial matrix, including interstitial collagens such as fibrillar and fibril-associated collagens and non-collagenous glycoproteins like fibronectin and elastin. http://purl.obolibrary.org/obo/GO_0140152 collagenous component of interstitial matrix http://purl.obolibrary.org/obo/GO_0030312 external encapsulating structure Main components of the interstitial matrix solid phase, including fibrillar and fibril-associated collagens. http://purl.obolibrary.org/obo/GO_0140154 chicken-wire-like collagen network http://purl.obolibrary.org/obo/GO_0098645 complex of network-forming collagens Network-forming collagens can either form a chicken-wire-like network or a hexagonal network. Collagen type IV forms a chicken-wire-like structure and is found in the basement membrane. http://purl.obolibrary.org/obo/CL_4301579 CBX MLI Megf11 Gaba_1 molecular layer interneuron (Mmus) http://purl.obolibrary.org/obo/CL_4300351 CBX MLI Megf11 Gaba molecular layer interneuron (Mmus) A molecular layer interneuron of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Dnah11 (Mmus), Sla (Mmus), Gldc (Mmus), Sdk2 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1149 CBX MLI Megf11 Gaba_1. http://purl.obolibrary.org/obo/UBERON_6000002 arthropod tagma http://purl.obolibrary.org/obo/UBERON_0011676 subdivision of organism along main body axis One of the main divisions of the whole organism of arthropods formed from groups of segments. http://purl.obolibrary.org/obo/UBERON_6000137 embryonic tagma http://purl.obolibrary.org/obo/UBERON_6000002 arthropod tagma Any tagma (UBERON:6000002) that is part of some embryo (UBERON:6000052). http://purl.obolibrary.org/obo/UBERON_6001728 insect larval tagma http://purl.obolibrary.org/obo/UBERON_6000002 arthropod tagma Any tagma (UBERON:6000002) that is part of some larva (UBERON:6001727). http://purl.obolibrary.org/obo/UBERON_6001730 insect larval head http://purl.obolibrary.org/obo/UBERON_0000033 head Any head that is part of some larva. http://purl.obolibrary.org/obo/UBERON_6002639 insect larval sense organ http://purl.obolibrary.org/obo/UBERON_0000020 sense organ Any sense organ that is part of some larva. http://purl.obolibrary.org/obo/UBERON_6003005 insect adult tagma http://purl.obolibrary.org/obo/UBERON_6000002 arthropod tagma Any tagma (UBERON:6000002) that is part of some adult (UBERON:6003004). http://purl.obolibrary.org/obo/UBERON_6003007 insect adult head http://purl.obolibrary.org/obo/UBERON_6003005 insect adult tagma Head of the adult organism. http://purl.obolibrary.org/obo/UBERON_6007240 insect embryonic/larval sensillum http://purl.obolibrary.org/obo/UBERON_6002639 insect larval sense organ Any sensillum (UBERON:6007152) that is part of some larva (UBERON:6001727). http://purl.obolibrary.org/obo/UBERON_6007242 insect embryonic/larval head sensillum http://purl.obolibrary.org/obo/UBERON_6007280 insect embryonic/larval head sense organ Any sensillum (UBERON:6007152) that is part of some larval head (UBERON:6001730). http://purl.obolibrary.org/obo/UBERON_6007280 insect embryonic/larval head sense organ http://purl.obolibrary.org/obo/UBERON_6002639 insect larval sense organ Any sense organ (UBERON:6005155) that is part of some larval head (UBERON:6001730). http://purl.obolibrary.org/obo/GO_0061900 glial cell activation http://purl.obolibrary.org/obo/GO_0001775 cell activation A change in morphology and behavior of a glial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. http://purl.obolibrary.org/obo/UBERON_0036217 coelomic fluid http://purl.obolibrary.org/obo/UBERON_0006314 bodily fluid A bodily fluid that is located in the coelom. http://purl.obolibrary.org/obo/UBERON_0036242 post-embryonic notochord http://purl.obolibrary.org/obo/UBERON_0002328 notochord A notochord that has persisted beyond the embryonic stage. http://purl.obolibrary.org/obo/UBERON_0036243 vaginal fluid http://purl.obolibrary.org/obo/UBERON_0006314 bodily fluid Fluid that lines the vaginal walls that consists of multiple secretions that collect in the vagina from different glands. http://purl.obolibrary.org/obo/UBERON_0036262 uterine ligament http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure Any of the eight ligaments pertaining to the uterus including the anterior, posterior, lateral, sacro-uterine and round ligaments. http://purl.obolibrary.org/obo/PATO_0045086 normal occurrence http://purl.obolibrary.org/obo/PATO_0045073 normal process quality An occurrence which is relatively normal. http://purl.obolibrary.org/obo/GO_0140244 regulation of translation at presynapse http://purl.obolibrary.org/obo/GO_0140243 regulation of translation at synapse Any process that regulates translation occurring at the presynapse. http://purl.obolibrary.org/obo/GO_0106214 regulation of vesicle fusion with Golgi apparatus http://purl.obolibrary.org/obo/GO_1903358 regulation of Golgi organization Any process that modulates the frequency, rate or extent of vesicle fusion with Golgi apparatus. http://purl.obolibrary.org/obo/GO_0106215 negative regulation of vesicle fusion with Golgi apparatus http://purl.obolibrary.org/obo/GO_0106214 regulation of vesicle fusion with Golgi apparatus Any process that stops, prevents or reduces the frequency, rate or extent of vesicle fustion with Golgi apparatus. http://purl.obolibrary.org/obo/GO_0106216 positive regulation of vesicle fusion with Golgi apparatus http://purl.obolibrary.org/obo/GO_0106214 regulation of vesicle fusion with Golgi apparatus Any process that activates or increases the frequency, rate or extent of vesicle fusion with Golgi apparatus. http://purl.obolibrary.org/obo/GO_0120213 regulation of histidine biosynthetic process http://purl.obolibrary.org/obo/GO_2000282 regulation of amino acid biosynthetic process Any process that modulates the frequency, rate or extent of histidine biosynthetic process. http://purl.obolibrary.org/obo/GO_0120214 negative regulation of histidine biosynthetic process http://purl.obolibrary.org/obo/GO_0120213 regulation of histidine biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of histidine biosynthetic process. http://purl.obolibrary.org/obo/GO_0120215 positive regulation of histidine biosynthetic process http://purl.obolibrary.org/obo/GO_0120213 regulation of histidine biosynthetic process Any process that activates or increases the frequency, rate or extent of histidine biosynthetic process. http://purl.obolibrary.org/obo/GO_0150106 regulation of protein localization to cell-cell junction http://purl.obolibrary.org/obo/GO_0032880 regulation of protein localization Any process that modulates the frequency, rate or extent of protein localization to cell-cell junction. http://purl.obolibrary.org/obo/GO_0150107 positive regulation of protein localization to cell-cell junction http://purl.obolibrary.org/obo/GO_0150106 regulation of protein localization to cell-cell junction Any process that activates or increases the frequency, rate or extent of protein localization to cell-cell junction. http://purl.obolibrary.org/obo/CL_4023058 mesothelial fibroblast of the leptomeninx http://purl.obolibrary.org/obo/CL_4023054 mesothelial fibroblast A mesothelial fibroblast found in the leptomeninx. http://purl.obolibrary.org/obo/CL_0008048 upper motor neuron http://purl.obolibrary.org/obo/CL_0000679 glutamatergic neuron A glutamatergic motor neuron with a soma in the brainstem or cerebral cortex. They do not synapse directly to muscles but rather to lower motor neurons, which do. They are the main controllers of voluntary movement. http://purl.obolibrary.org/obo/CL_4023053 spinal interneuron synapsing Betz cell http://purl.obolibrary.org/obo/CL_0008049 Betz cell A Betz cell that syanpses with spinal interneurons. http://purl.obolibrary.org/obo/CL_0009031 T cell of appendix http://purl.obolibrary.org/obo/CL_0000084 T cell A T cell that is located in a vermiform appendix. http://purl.obolibrary.org/obo/GO_0140669 negative regulation of oxytocin production http://purl.obolibrary.org/obo/GO_0140667 regulation of oxytocin production Any process that stops, prevents, or reduces the rate of production of oxytocin. http://purl.obolibrary.org/obo/CL_0011030 dermal microvascular endothelial cell http://purl.obolibrary.org/obo/CL_2000010 dermis blood vessel endothelial cell Any microvascular endothelial cell that is part of the dermis. http://purl.obolibrary.org/obo/PR_000050522 medium-wave-sensitive opsin (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A medium-wave-sensitive opsin that is encoded in the genome of human. http://purl.obolibrary.org/obo/CL_4023128 rostral periventricular region of the third ventricle KNDy neuron http://purl.obolibrary.org/obo/CL_4023125 KNDy neuron a KNDy neuron that is located in the rostral periventricular region of the third ventricle. http://purl.obolibrary.org/obo/CL_4023122 oxytocin receptor sst GABAergic cortical interneuron http://purl.obolibrary.org/obo/CL_0010011 cerebral cortex GABAergic interneuron An interneuron located in the cerebral cortex that expresses the oxytocin receptor. These interneurons also express somatostatin. http://purl.obolibrary.org/obo/CL_0009114 monocytoid B cell http://purl.obolibrary.org/obo/CL_0000236 B cell A B cell found in the perisinusoidal area of a lymph node. In humans, monocytoid B cells are a morphologically distinct B cell population (oval nuclei, abundant cytoplasm, monocyte-like appearance), share many similarities with marginal zone B cells including marker expression, and are increased in disease settings. http://purl.obolibrary.org/obo/CL_4030010 epithelial cell of proximal tubule segment 2 http://purl.obolibrary.org/obo/CL_1000838 kidney proximal convoluted tubule epithelial cell A brush border cell that is part of segment 2 (S2) of the proximal tubule epithelium, located in the renal cortex. In addition to its reabsorptive functions, it is also specialized in the secretion of organic anions and cations, including para-aminohippurate. http://purl.obolibrary.org/obo/PATO_0070061 double bouquet morphology http://purl.obolibrary.org/obo/PATO_0070027 bitufted dendrite cell morphology A cell morphology that inheres in neurons with bitufted dendritic morphology but with the special feature of a tight fascicular axonal cylinder that resembles a 'horse tail'. http://purl.obolibrary.org/obo/CL_0004243 WF3-2 amacrine cell http://purl.obolibrary.org/obo/CL_0004253 wide field retinal amacrine cell An amacrine cell with a wild dendritic field, dendrites in S3, and post-synaptic terminals in S3. Dendrites have spikes, cross over each other, and cover a larger volume than dendrties of W3-1 retinal amacrine cells. http://purl.obolibrary.org/obo/CL_0004223 AB diffuse-1 amacrine cell http://purl.obolibrary.org/obo/CL_0004251 narrow field retinal amacrine cell A amacrine cell with a small dendritic field and post-synaptic terminals in S1, S2, S3, and S4. AB diffuse-1 amacrine cells have a tent-shaped dendritic arbor and undulate dendrites. http://purl.obolibrary.org/obo/CL_0020011 hair follicle associated fibroblast http://purl.obolibrary.org/obo/CL_0002620 skin fibroblast A specialized dermal fibroblast within the hair follicle mesenchymal compartment that participates in epithelial-mesenchymal signaling to regulate hair morphogenesis, cycling, and homeostasis through production of inductive signals and extracellular matrix maintenance. http://purl.obolibrary.org/obo/CL_0020012 hair follicle isthmus-associated fibroblast http://purl.obolibrary.org/obo/CL_0020011 hair follicle associated fibroblast A fibroblast that is part of the hair follicle isthmus (mid-hair shaft). In humans, this cell expresses CRABP1/COCH/RSPO4 and tendon-associated genes (MKX, TNMD). http://purl.obolibrary.org/obo/CL_0020013 dermal sheath fibroblast http://purl.obolibrary.org/obo/CL_0020011 hair follicle associated fibroblast A fibroblast forming the connective tissue sheath that encloses the hair follicle epithelium from the level of the bulge downward to the hair bulb. This cell expresses characteristic markers, including DPEP1 in humans and COL11A1 and ACTA2 (alpha-smooth muscle actin) in mice and humans. Dermal sheath fibroblast possesses contractile properties mediated by calcium-calmodulin-myosin light chain kinase signalling, generating centripetal force during hair follicle catagen that relocates the dermal papilla to the stem cell niche. http://purl.obolibrary.org/obo/CL_0020014 intrinsically photosensitive retinal ganglion cell http://purl.obolibrary.org/obo/CL_0000740 retinal ganglion cell A retinal ganglion cell that is intrinsically photosensitive, functioning as a non-image-forming photoreceptor, distinguished from rod and cone photoreceptors by the expression of the photopigment melanopsin in mice and humans (Hattar et al., 2002; Tri Hoang Do & Yau, 2015). Located primarily in the ganglion cell layer with some displaced somata in the inner nuclear layer, this neuron depolarises directly in response to environmental irradiance (Tri Hoang Do & Yau, 2015). It projects via the retinohypothalamic tract to central targets, including the suprachiasmatic nucleus (SCN) for circadian photoentrainment and the olivary pretectal nucleus (OPN) for the pupillary light reflex. http://purl.obolibrary.org/obo/CL_0020015 transitional principal-intercalated cell of kidney collecting duct http://purl.obolibrary.org/obo/CL_1000454 kidney collecting duct epithelial cell A transitional cell located in the renal collecting duct that co-expresses markers of both principal cell (PC) and intercalated cell (IC). This hybrid cell is enriched in Chronic Kidney Disease (CKD). http://purl.obolibrary.org/obo/CL_4072103 hair follicle dermal stem cell http://purl.obolibrary.org/obo/CL_0002559 hair follicle cell A bipotent mesenchymal stem cell that resides in the dermal sheath, specifically within the dermal sheath cup at the base of the hair follicle, characterized by its capacity for self-renewal and differentiation into both dermal sheath and dermal papilla cells throughout hair cycling. In humans, this cell is marked by enriched expression of gremlin-2 (GREM2) and dipeptidase-1 (DPEP1), and acts as a progenitor reservoir sustaining and regenerating the follicle's mesenchymal compartments. http://purl.obolibrary.org/obo/CL_4310083 GPin-BF cholinergic-GABAergic neuron (Primate) http://purl.obolibrary.org/obo/CL_0008061 GABA-Chol neuron A GABA-Chol neuron of the Primates brain. These cells are located in the striatum, external segment of globus pallidus . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:GPin-BF Cholinergic GABA. http://purl.obolibrary.org/obo/CL_4310084 striatal LAMP5 CXCL14 GABAergic interneuron (Primate) http://purl.obolibrary.org/obo/CL_4023011 lamp5 GABAergic interneuron A lamp5 GABAergic interneuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:LAMP5-CXCL14 GABA. http://purl.obolibrary.org/obo/CL_4310085 striatal LAMP5 LHX6 GABAergic interneuron (Primate) http://purl.obolibrary.org/obo/CL_4042013 Lamp5 Lhx6 neuron A Lamp5 Lhx6 neuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:LAMP5-LHX6 GABA. http://purl.obolibrary.org/obo/CL_4310088 BF SKOR1 Glut glutamatergic neuron of the basal ganglia (Primate) http://purl.obolibrary.org/obo/CL_0000700 dopaminergic neuron A glutamatergic neuron of the basal ganglia of the Primates brain. These cells are located in the striatum, external segment of globus pallidus . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:BF SKOR1 Glut. http://purl.obolibrary.org/obo/CL_4310093 arkypallidal neuron (Primate) http://purl.obolibrary.org/obo/CL_0020010 arkypallidal neuron A arkypallidal neuron of the Primates brain. These cells are located in the striatum, external segment of globus pallidus . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:GPe MEIS2-SOX6 GABA. http://purl.obolibrary.org/obo/CL_4310094 prototypic neuron (Primate) http://purl.obolibrary.org/obo/CL_0020009 prototypic neuron A prototypic neuron of the Primates brain. These cells are located in the striatum, external segment of globus pallidus . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:GPe SOX6-CTXND1 GABA. http://purl.obolibrary.org/obo/CL_4310095 GPi Core neuron (Primate) http://purl.obolibrary.org/obo/CL_0020003 internal globus pallidus core projecting neuron A internal globus pallidus core projecting neuron of the Primates brain. These cells are located in the internal segment of globus pallidus . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:GPi Core. http://purl.obolibrary.org/obo/CL_4310096 GPi Shell neuron (Primate) http://purl.obolibrary.org/obo/CL_0020004 internal globus pallidus shell projection neuron A internal globus pallidus shell projection neuron of the Primates brain. These cells are located in the striatum, external segment of globus pallidus, internal segment of globus pallidus . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:GPi Shell. http://purl.obolibrary.org/obo/CL_4310100 GPe-NDB-SI LHX6-LHX8-GBX1 GABA GABAergic interneuron (Primate) http://purl.obolibrary.org/obo/CL_0011005 GABAergic interneuron A GABAergic interneuron of the Primates brain. These cells are located in the striatum, external segment of globus pallidus . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:GPe-NDB-SI LHX6-LHX8-GBX1 GABA. http://purl.obolibrary.org/obo/CL_4310104 Islands of Calleja granule cell (Primate) http://purl.obolibrary.org/obo/CL_4030053 Islands of Calleja granule cell A Islands of Calleja granule cell of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:OT D1 ICj. http://purl.obolibrary.org/obo/CL_4310109 SN-VTR CALB1 Dopa substantia nigra dopaminergic neuron (Primate) http://purl.obolibrary.org/obo/CL_4042025 substantia nigra dopaminergic neuron A substantia nigra dopaminergic neuron of the Primates brain. These cells are located in the substantia nigra . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:SN-VTR CALB1 Dopa. http://purl.obolibrary.org/obo/CL_4310110 SN EBF2 GABA GABAergic interneuron (Primate) http://purl.obolibrary.org/obo/CL_0011005 GABAergic interneuron A GABAergic interneuron of the Primates brain. These cells are located in the striatum, substantia nigra . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:SN EBF2 GABA. http://purl.obolibrary.org/obo/CL_4310111 SN-VTR GAD2 Dopa dopaminergic neuron (Primate) http://purl.obolibrary.org/obo/CL_4042025 substantia nigra dopaminergic neuron A dopaminergic neuron of the Primates brain. These cells are located in the striatum, substantia nigra . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:SN-VTR GAD2 Dopa. http://purl.obolibrary.org/obo/CL_4310112 SN GATA3-PAX8 GABA GABAergic interneuron (Primate) http://purl.obolibrary.org/obo/CL_0011005 GABAergic interneuron A GABAergic interneuron of the Primates brain. These cells are located in the substantia nigra . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:SN GATA3-PAX8 GABA. http://purl.obolibrary.org/obo/CL_4310113 SN GATA3-PVALB GABA GABAergic neuron (Primate) http://purl.obolibrary.org/obo/CL_0000617 GABAergic neuron A GABAergic neuron of the Primates brain. These cells are located in the substantia nigra . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:SN GATA3-PVALB GABA. http://purl.obolibrary.org/obo/CL_4310114 SN SEMA5A GABA GABAergic interneuron (Primate) http://purl.obolibrary.org/obo/CL_0011005 GABAergic interneuron A GABAergic interneuron of the Primates brain. These cells are located in the striatum, subthalamic nucleus, substantia nigra . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:SN SEMA5A GABA. http://purl.obolibrary.org/obo/CL_4310115 SN SOX6 Dopa substantia nigra dopaminergic neuron (Primate) http://purl.obolibrary.org/obo/CL_4042025 substantia nigra dopaminergic neuron A substantia nigra dopaminergic neuron of the Primates brain. These cells are located in the substantia nigra . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:SN SOX6 Dopa. http://purl.obolibrary.org/obo/CL_4310117 SN-VTR-HTH GATA3-TCF7L2 GABA GABAergic interneuron (Primate) http://purl.obolibrary.org/obo/CL_0011005 GABAergic interneuron A GABAergic interneuron of the Primates brain. These cells are located in the substantia nigra . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:SN-VTR-HTH GATA3-TCF7L2 GABA. http://purl.obolibrary.org/obo/CL_4310118 STH PVALB-PITX2 Glut glutamatergic neuron of the basal ganglia (Primate) http://purl.obolibrary.org/obo/CL_0000700 dopaminergic neuron A glutamatergic neuron of the basal ganglia of the Primates brain. These cells are located in the subthalamic nucleus . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STH PVALB-PITX2 Glut. http://purl.obolibrary.org/obo/CL_4310120 striatal pthlh-expressing interneuron (Primate) http://purl.obolibrary.org/obo/CL_4042023 striatal pthlh-expressing interneuron A striatal pthlh-expressing interneuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STR FS PTHLH-PVALB GABA. http://purl.obolibrary.org/obo/CL_4310121 striatal SST-LYPD6-RSPO2 GABAergic interneuron (Primate) http://purl.obolibrary.org/obo/CL_0011005 GABAergic interneuron A GABAergic interneuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STR LYPD6-RSPO2 GABA. http://purl.obolibrary.org/obo/CL_4310122 striatal SST-ADARB2 GABAergic interneuron (Primate) http://purl.obolibrary.org/obo/CL_4023017 sst GABAergic interneuron A sst GABAergic interneuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STR SST-ADARB2 GABA. http://purl.obolibrary.org/obo/CL_4310123 striatal SST-CHODL GABAergic interneuron (Primate) http://purl.obolibrary.org/obo/CL_4023121 sst chodl GABAergic interneuron A sst chodl GABAergic interneuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STR SST-CHODL GABA. http://purl.obolibrary.org/obo/CL_4310124 striatal SST-RSPO2 GABAergic interneuron (Primate) http://purl.obolibrary.org/obo/CL_4023017 sst GABAergic interneuron A sst GABAergic interneuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STR SST-RSPO2 GABA. http://purl.obolibrary.org/obo/CL_4310125 STR TAC3-PLPP4 GABA TAC3-positive striatal interneuron (Primate) http://purl.obolibrary.org/obo/CL_4042001 TAC3-positive striatal interneuron A TAC3-positive striatal interneuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STR TAC3-PLPP4 GABA. http://purl.obolibrary.org/obo/CL_4310126 STR-BF TAC3-PLPP4-LHX8 GABA TAC3-positive striatal interneuron (Primate) http://purl.obolibrary.org/obo/CL_4042001 TAC3-positive striatal interneuron A TAC3-positive striatal interneuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STR-BF TAC3-PLPP4-LHX8 GABA. http://purl.obolibrary.org/obo/CL_4310127 striatal VIP GABAergic interneuron (Primate) http://purl.obolibrary.org/obo/CL_4023016 VIP GABAergic interneuron A VIP GABAergic interneuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:VIP GABA. http://purl.obolibrary.org/obo/CL_4310128 STRd cholinergic-GABAergic neuron (Primate) http://purl.obolibrary.org/obo/CL_0020007 dorso-striatal cholinergic-GABAergic neuron A dorso-striatal cholinergic-GABAergic neuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STRd Cholinergic GABA. http://purl.obolibrary.org/obo/CL_4310129 STRd D1 Matrix medium spiny neuron (Primate) http://purl.obolibrary.org/obo/CL_4030043 matrix D1 medium spiny neuron A matrix D1 medium spiny neuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STRd D1 Matrix MSN. http://purl.obolibrary.org/obo/CL_4310130 striosomal D1 medium spiny neuron (Primate) http://purl.obolibrary.org/obo/CL_4030048 striosomal D1 medium spiny neuron A striosomal D1 medium spiny neuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STRd D1 Striosome MSN. http://purl.obolibrary.org/obo/CL_4310131 STRd D1/D2-hybrid medium spiny neuron (Primate) http://purl.obolibrary.org/obo/CL_4030050 D1/D2-hybrid medium spiny neuron A D1/D2-hybrid medium spiny neuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STR D1D2 Hybrid MSN. http://purl.obolibrary.org/obo/CL_4310132 STRd D2 Matrix medium spiny neuron (Primate) http://purl.obolibrary.org/obo/CL_4030047 matrix D2 medium spiny neuron A matrix D2 medium spiny neuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STRd D2 Matrix MSN. http://purl.obolibrary.org/obo/CL_4310133 STRd D2 Striomat hybrid medium spiny neuron (Primate) http://purl.obolibrary.org/obo/CL_4023029 indirect pathway medium spiny neuron A indirect pathway medium spiny neuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STRd D2 StrioMat Hybrid MSN. http://purl.obolibrary.org/obo/CL_4310134 striosomal D2 medium spiny neuron (Primate) http://purl.obolibrary.org/obo/CL_4030049 striosomal D2 medium spiny neuron A striosomal D2 medium spiny neuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STRd D2 Striosome MSN. http://purl.obolibrary.org/obo/CL_4310135 STR cholinergic-GABAergic neuron (Primate) http://purl.obolibrary.org/obo/CL_0020008 striatal cholinergic-GABAergic neuron A striatal cholinergic-GABAergic neuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STR Cholinergic GABA. http://purl.obolibrary.org/obo/CL_4310136 STRv D1 medium spiny neuron (Primate) http://purl.obolibrary.org/obo/CL_4030051 nucleus accumbens shell and olfactory tubercle D1 medium spiny neuron A nucleus accumbens shell and olfactory tubercle D1 medium spiny neuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STRv D1 MSN. http://purl.obolibrary.org/obo/CL_4310137 STRv D1-NUDAP medium spiny neuron (Primate) http://purl.obolibrary.org/obo/CL_4030054 D1-NUDAP medium spiny neuron A D1-NUDAP medium spiny neuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STRv D1 NUDAP MSN. http://purl.obolibrary.org/obo/CL_4310138 STRv D2 medium spiny neuron (Primate) http://purl.obolibrary.org/obo/CL_4030052 nucleus accumbens shell and olfactory tubercle D2 medium spiny neuron A nucleus accumbens shell and olfactory tubercle D2 medium spiny neuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STRv D2 MSN. http://purl.obolibrary.org/obo/CL_4310143 ZI-HTH GABA GABAergic interneuron (Primate) http://purl.obolibrary.org/obo/CL_0011005 GABAergic interneuron A GABAergic interneuron of the Primates brain. These cells are located in the substantia nigra . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:ZI-HTH GABA. http://purl.obolibrary.org/obo/CL_4310144 VTR-HTH Glut glutamatergic neuron of the basal ganglia (Primate) http://purl.obolibrary.org/obo/CL_0000700 dopaminergic neuron A glutamatergic neuron of the basal ganglia of the Primates brain. These cells are located in the striatum, subthalamic nucleus, substantia nigra . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:VTR-HTH Glut. http://purl.obolibrary.org/obo/CL_4310145 AMY-SLEA-BNST D1 GABA GABAergic interneuron (Primate) http://purl.obolibrary.org/obo/CL_0011005 GABAergic interneuron A GABAergic interneuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:AMY-SLEA-BNST D1 GABA. http://purl.obolibrary.org/obo/CL_4310146 AMY-SLEA-BNST GABA GABAergic interneuron (Primate) http://purl.obolibrary.org/obo/CL_0011005 GABAergic interneuron A GABAergic interneuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:AMY-SLEA-BNST GABA. http://purl.obolibrary.org/obo/CL_4310147 OB Dopa-GABA neuron (Primate) http://purl.obolibrary.org/obo/CL_0020006 OB-Dopa-GABA A OB-Dopa-GABA of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:OB Dopa-GABA. http://purl.obolibrary.org/obo/CL_4310148 OB FRMD7 GABA GABAergic neuron (Primate) http://purl.obolibrary.org/obo/CL_0000617 GABAergic neuron A GABAergic neuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:OB FRMD7 GABA. http://purl.obolibrary.org/obo/CL_0020029 cuboidal epithelial cell http://purl.obolibrary.org/obo/CL_0000075 columnar/cuboidal epithelial cell An epithelial cell that has a cuboidal morphology. http://purl.obolibrary.org/obo/CL_0020035 intestinal intraepithelial lymphocyte http://purl.obolibrary.org/obo/CL_0002496 intraepithelial lymphocyte A T cell that is located in the intestinal epithelium and is capable of a mucosal immune response. http://purl.obolibrary.org/obo/CL_0020030 CD4-positive exhausted alpha-beta T cell http://purl.obolibrary.org/obo/CL_0000624 CD4-positive, alpha-beta T cell A CD4-positive alpha-beta T cell that displays impaired function and altered differentiation as a result of chronic antigenic stimulation (e.g., chronic infection, tumors, or persistent inflammation). This state is characterised by sustained expression of PD-1 as a shared feature. Additional exhaustion-associated molecules, including the transcription factor TOX, and context- or stage-dependent changes in markers such as LAG-3, TIM-3, CD39, and T-bet, may also be observed; however, the expression levels of these molecules vary depending on exhaustion stage and tissue environment. http://purl.obolibrary.org/obo/CL_0020028 hybrid osteochondral skeletal cell http://purl.obolibrary.org/obo/CL_0007001 skeletogenic cell A skeletal cell at the periosteal surface of the murine rib that displays hybrid osteochondral properties, emerging within the large callus that bridges segmental rib defects. It derives from a Sox9-expressing periosteal skeletal stem/progenitor subpopulation that constitutes only a small fraction of uninjured rib periosteum. After injury, these cells populate the callus and co-express cartilage and bone regulators Sox9 and Runx2, as well as matrix genes Col2a1 and Col1a1, while exhibiting dual chondrocyte/osteoblast properties. http://purl.obolibrary.org/obo/CL_0020031 CD8-positive exhausted alpha-beta T cell http://purl.obolibrary.org/obo/CL_0000625 CD8-positive, alpha-beta T cell A CD8-positive alpha-beta T cell that displays impaired function and altered differentiation as a result of chronic antigenic stimulation (e.g., chronic infection, tumours, or persistent inflammation). This state is characterised by sustained expression of PD-1 as a shared feature. Additional exhaustion-associated molecules, including expression of the transcription factor TOX and reduced T-bet, and context- or stage-dependent changes in markers such as LAG-3, TIM-3, CD39, and EOMES, may also be observed; however, the expression levels of these molecules vary depending on exhaustion stage and disease context. http://purl.obolibrary.org/obo/CL_0020032 oRGC2 http://purl.obolibrary.org/obo/CL_0000740 retinal ganglion cell A conserved retinal ganglion cell orthotype whose transcriptomic profile groups together ON parasol RGCs from primate foveal and peripheral retina with their molecularly homologous mouse α RGC subtype (ON-transient α RGC, C41) (Hahn et al., 2023; Tran et al., 2019). Reference to the transcriptomic evidence is found at: GSE237215. http://purl.obolibrary.org/obo/CL_0020033 stem cell memory CD4-positive, alpha-beta T cell http://purl.obolibrary.org/obo/CL_0000897 CD4-positive, alpha-beta memory T cell A CD4-positive memory alpha-beta T cell with stem-like properties that is long-lived, retains a naïve-like phenotype, and exhibits self-renewal and multipotent differentiation capacity. This cell acts as a stem-like reservoir capable of regenerating central and effector memory T cell subsets. http://purl.obolibrary.org/obo/CL_0020034 stem cell memory CD8-positive, alpha-beta T cell http://purl.obolibrary.org/obo/CL_0000909 CD8-positive, alpha-beta memory T cell A CD8-positive memory alpha-beta T cell with stem-like properties that is long-lived, retains a naïve-like phenotype, and exhibits self-renewal and multipotent differentiation capacity. This cell acts as a stem-like reservoir capable of regenerating central and effector memory T cell subsets. http://purl.obolibrary.org/obo/CL_0020036 oRGC1 http://purl.obolibrary.org/obo/CL_0000740 retinal ganglion cell A conserved retinal ganglion cell orthotype whose transcriptomic profile groups together OFF midget RGCs from primate foveal and peripheral retina with their molecularly homologous mouse alpha RGC subtype (OFF-sustained alpha-RGC, C42) (Hahn et al., 2023; Tran et al., 2019). Reference to the transcriptomic evidence is found at: GSE237215. http://purl.obolibrary.org/obo/CL_0020037 superficial zone articular chondrocyte http://purl.obolibrary.org/obo/CL_1001607 articular chondrocyte An articular chondrocyte located in the most superficial zone of articular cartilage, characterized by flattened morphology and tangential alignment parallel to the joint surface, and residing within a matrix of fine collagen fibrils and relatively low proteoglycan content. In mice and humans, this cell typically expresses lubricin (PRG4) and contributes to lubrication and resistance to shear and tensile forces at the cartilage surface. http://purl.obolibrary.org/obo/CL_0020038 middle zone articular chondrocyte http://purl.obolibrary.org/obo/CL_1001607 articular chondrocyte An articular chondrocyte located in the middle (transitional) zone of articular cartilage, characterized by round morphology and relatively random spatial organization, and residing in a matrix enriched in proteoglycans and thicker collagen fibrils oriented obliquely to the articular surface. This cell contributes to the largest volume fraction of articular cartilage and functions primarily in distributing and absorbing compressive loads between the superficial and deep zones. http://purl.obolibrary.org/obo/CL_0020039 deep zone articular chondrocyte http://purl.obolibrary.org/obo/CL_1001607 articular chondrocyte An articular chondrocyte located in the deep (radial) zone of articular cartilage, characterized by columnar arrangement perpendicular to the joint surface and residence within a matrix containing the highest proteoglycan concentration and large-diameter collagen fibrils oriented radially. In humans, this cell expresses collagen type X (COL10A1) and provides maximal resistance to compressive forces. It is positioned adjacent to the tidemark, where collagen fibrils extend into the calcified cartilage to anchor the articular cartilage to subchondral bone. http://purl.obolibrary.org/obo/CL_0020040 calcified zone articular chondrocyte http://purl.obolibrary.org/obo/CL_1001607 articular chondrocyte An articular chondrocyte located in the calcified cartilage zone below the tidemark at the interface between articular cartilage and subchondral bone, embedded within a mineralized extracellular matrix. In humans, this cell exhibits a hypertrophic-like phenotype and typically expresses collagen type X (COL10A1). Together with the surrounding calcified matrix, it forms a transitional region that mechanically couples the deep articular cartilage to the underlying subchondral bone. http://purl.obolibrary.org/obo/CL_0020041 oRGC4 http://purl.obolibrary.org/obo/CL_0000740 retinal ganglion cell A conserved retinal ganglion cell orthotype whose transcriptomic profile groups together ON midget RGCs from primate foveal and peripheral retina with their molecularly homologous mouse alpha RGC subtype (ON-sustained α RGC, C43) (Hahn et al., 2023; Tran et al., 2019). Reference to the transcriptomic evidence is found at: GSE237215. http://purl.obolibrary.org/obo/CL_0020042 oRGC5 http://purl.obolibrary.org/obo/CL_0000740 retinal ganglion cell A conserved retinal ganglion cell orthotype whose transcriptomic profile groups together OFF parasol RGCs from primate foveal and peripheral retina with their molecularly homologous mouse α RGC subtype (OFF-transient α RGC, C45) (Hahn et al., 2023; Tran et al., 2019). Reference to transcriptomic evidence can be found at: GSE237215. http://purl.obolibrary.org/obo/CL_0020043 fasciacyte http://purl.obolibrary.org/obo/CL_0000499 stromal cell A mesenchymal stromal cell of the deep fascia (e.g., fascia lata) that is vimentin-positive, CD68-negative, and S-100A4-positive, organized in small clusters at the interface between fibrous fascial sublayers and loose connective tissue. It is specialized for hyaluronan-rich ECM biosynthesis, as evidenced by HAS2 mRNA expression, Alcian Blue staining, and anti-HABP immunoreactivity, and functions to regulate fascial gliding and viscoelasticity. http://purl.obolibrary.org/obo/CL_0020044 migratory muscle precursor http://purl.obolibrary.org/obo/CL_0000680 muscle precursor cell Muscle precursor cells that delaminate from the dermomyotome after epithelial-to-mesenchymal transition (EMT) and undergo long-range migration while retaining proliferative capacity. http://purl.obolibrary.org/obo/CL_0020045 Dogiel type II neuron http://purl.obolibrary.org/obo/CL_0007011 enteric neuron A neuron characterised by Dogiel type II morphology: a large, smooth, oval soma bearing multiple long axon-like processes (multiaxonal) that extend without branching until they reach their targets. The soma lacks the short lamellar or spiny dendrites characteristic of Dogiel type I neurons. Dogiel type II neurons were first described by Alexander Dogiel in 1899 based on methylene blue staining in gastrointestinal ganglia. In the enteric nervous system, Dogiel type II neurons correspond to intrinsic primary afferent neurons (IPANs) and exhibit AH-type electrophysiology (prolonged afterhyperpolarization following an action potential). http://purl.obolibrary.org/obo/CL_0020046 intrinsic primary afferent neuron of myenteric plexus http://purl.obolibrary.org/obo/CL_3000004 peripheral sensory neuron A sensory neuron of the enteric nervous system whose soma resides in the myenteric plexus and which functions as the afferent limb of intrinsic reflex circuits controlling motility, secretion, and blood flow. This neuron is characterised by Dogiel type II morphology (large smooth soma with multiple long axon-like processes), AH-type electrophysiology (prolonged afterhyperpolarization following an action potential), and is immunopositive for choline acetyltransferase (ChAT) and immunonegative for neuronal nitric oxide synthase (NOS1). http://purl.obolibrary.org/obo/CL_0020047 interneuron of myenteric plexus http://purl.obolibrary.org/obo/CL_0007011 enteric neuron An interneuron of the enteric nervous system whose soma resides in the myenteric plexus. Interneurons of the myenteric plexus integrate sensory input from intrinsic primary afferent neurons (IPANs) and modulate motor output to smooth muscle and secretory epithelia by synapsing onto motor neurons and other interneurons within the plexus. http://purl.obolibrary.org/obo/CL_0020048 secretomotor/vasodilator neuron of myenteric plexus http://purl.obolibrary.org/obo/CL_0007011 enteric neuron An enteric neuron whose soma resides in the myenteric plexus and which controls mucosal secretion and blood flow by innervating secretory epithelia and submucosal blood vessels. This neuron is characterised by expression of vasoactive intestinal peptide (VIP). In mouse, two Glp2r+ subtypes have been identified: PSVN1 (VIP+, non-cholinergic) and PSVN2 (ChAT+, cholinergic). In human, only the VIP+ non-cholinergic subtype has been detected. http://purl.obolibrary.org/obo/CL_0020049 intestinofugal neuron http://purl.obolibrary.org/obo/CL_0007011 enteric neuron An enteric neuron whose soma resides in the myenteric plexus of the intestine and whose axon projects outside the gut wall to synapse on neurons in prevertebral sympathetic ganglia (celiac, superior mesenteric, or inferior mesenteric ganglia). This neuron provides a pathway for gut-to-brain communication via sympathetic prevertebral ganglia. In humans, 89% are immunopositive for choline acetyltransferase (ChAT); CART (cocaine- and amphetamine-regulated transcript) is NOT a human marker (0% CART+) but is present in rodent viscerofugal neurons. http://purl.obolibrary.org/obo/CL_0020050 ascending interneuron of myenteric plexus http://purl.obolibrary.org/obo/CL_0020047 interneuron of myenteric plexus An interneuron of the myenteric plexus whose axon projects orally (in the ascending direction) along the gut axis. This neuron is immunopositive for choline acetyltransferase (ChAT) and enkephalin (ENK), and forms the excitatory limb of ascending reflex pathways that coordinate peristalsis. http://purl.obolibrary.org/obo/CL_0020051 descending interneuron of myenteric plexus http://purl.obolibrary.org/obo/CL_0020047 interneuron of myenteric plexus An interneuron of the myenteric plexus whose axon projects aborally (in the descending direction) along the gut axis. This neuron class encompasses multiple chemically diverse subtypes including serotonergic (5-HT+), nitrergic (NOS1+), and other populations, forming the inhibitory limb of descending reflex pathways. http://purl.obolibrary.org/obo/CL_0020052 stubby Dogiel type I neuron of myenteric plexus http://purl.obolibrary.org/obo/CL_4047038 dogiel type I neuron A Dogiel type I neuron of the myenteric plexus characterised by stubby (lamellar) dendrite morphology with broad, flattened dendritic expansions. This neuron is immunopositive for choline acetyltransferase (ChAT) and immunonegative for neuronal nitric oxide synthase (NOS1), corresponding to excitatory motor neurons of the enteric nervous system. http://purl.obolibrary.org/obo/CL_0020053 spiny Dogiel type I neuron of myenteric plexus http://purl.obolibrary.org/obo/CL_4047038 dogiel type I neuron A Dogiel type I neuron of the myenteric plexus characterised by spiny (spine-like) dendrite morphology with numerous short projections along the dendrites. This neuron is immunopositive for neuronal nitric oxide synthase (NOS1) and immunonegative for choline acetyltransferase (ChAT), corresponding to inhibitory motor neurons of the enteric nervous system. http://purl.obolibrary.org/obo/CL_0020054 Dogiel type II neuron of myenteric plexus http://purl.obolibrary.org/obo/CL_0020046 intrinsic primary afferent neuron of myenteric plexus An intrinsic primary afferent neuron of the myenteric plexus characterised by Dogiel type II morphology: a large, smooth, oval soma bearing multiple long axon-like processes that extend without branching until they reach their targets in both the myenteric and submucosal plexuses and the mucosa. The soma lacks the dendrites characteristic of Dogiel type I neurons and is larger in cross-sectional area than either motor neuron type. This neuron is immunopositive for choline acetyltransferase (ChAT) and immunonegative for neuronal nitric oxide synthase (NOS1). It exhibits AH-type electrophysiology, characterised by a prolonged afterhyperpolarization (AHP) following an action potential. Substance P (encoded by TAC1) expression has been reported in subsets across species. http://purl.obolibrary.org/obo/CL_0020055 calretinin-positive intrinsic primary afferent neuron of myenteric plexus http://purl.obolibrary.org/obo/CL_0020046 intrinsic primary afferent neuron of myenteric plexus An intrinsic primary afferent neuron of the myenteric plexus that is immunopositive for calretinin. This neuron shares the Dogiel type II morphology and AH-type electrophysiology of all myenteric IPANs, and is immunopositive for choline acetyltransferase (ChAT) and immunonegative for neuronal nitric oxide synthase (NOS1). http://purl.obolibrary.org/obo/CL_0020056 calretinin-negative intrinsic primary afferent neuron of myenteric plexus http://purl.obolibrary.org/obo/CL_0020046 intrinsic primary afferent neuron of myenteric plexus An intrinsic primary afferent neuron of the myenteric plexus that lacks calretinin expression. This neuron shares the Dogiel type II morphology and AH-type electrophysiology of all myenteric IPANs, and is immunopositive for choline acetyltransferase (ChAT) and immunonegative for neuronal nitric oxide synthase (NOS1). http://purl.obolibrary.org/obo/CL_0020057 cholinergic neuron of myenteric plexus http://purl.obolibrary.org/obo/CL_0007011 enteric neuron An enteric neuron whose soma resides in the myenteric plexus and which is capable of acetylcholine secretion, neurotransmission. This is a defined grouping class that autoclassifies stubby Dogiel type I neurons, intrinsic primary afferent neurons, ascending interneurons, and their morphological/chemical subterms. http://purl.obolibrary.org/obo/CL_0020058 nitrergic neuron of myenteric plexus http://purl.obolibrary.org/obo/CL_0007011 enteric neuron An enteric neuron whose soma resides in the myenteric plexus and which is capable of nitric oxide biosynthetic process. This is a defined grouping class that autoclassifies spiny Dogiel type I neurons (the nitrergic motor neuron morphotype). http://purl.obolibrary.org/obo/CL_4033175 dorsal root ganglion BRN3A neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A sensory neuron that has the soma located in the dorsal root ganglion and expresses the pan-sensory transcription factor POU domain, class 4, transcription factor 1 (BRN3A/POU4F1). In humans, BRN3A is expressed by approximately 98% of DRG neurons and serves as a broad marker for the sensory neuron population. http://purl.obolibrary.org/obo/CL_4033176 dorsal root ganglion CGRP neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A sensory neuron that has the soma located in the dorsal root ganglion and expresses the marker calcitonin gene-related peptide (CGRP). This peptidergic nociceptor subpopulation is involved in neurogenic inflammation and pain signaling. http://purl.obolibrary.org/obo/CL_4033177 dorsal root ganglion EDN1 neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A sensory neuron that has the soma located in the dorsal root ganglion and expresses the marker endothelin-1 (EDN1). Endothelin signaling in DRG neurons has been demonstrated in rat tissue. http://purl.obolibrary.org/obo/CL_4033178 dorsal root ganglion Nav1.7 neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A sensory neuron that has the soma located in the dorsal root ganglion and expresses the marker sodium channel protein type 9 subunit alpha (Nav1.7/SCN9A). Nav1.7 accounts for approximately 50% of total sodium channel expression in human DRG and is present in 54-57% of TrkA-positive nociceptors. http://purl.obolibrary.org/obo/CL_4033179 dorsal root ganglion Nav1.9 neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A sensory neuron that has the soma located in the dorsal root ganglion and expresses the marker sodium channel protein type 11 subunit alpha (Nav1.9/SCN11A). Nav1.9 is present in approximately 26% of TrkA-positive human DRG neurons and defines a nociceptor subpopulation. http://purl.obolibrary.org/obo/CL_4033180 dorsal root ganglion peripherin neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A sensory neuron that has the soma located in the dorsal root ganglion and expresses the intermediate filament protein peripherin (PRPH). Peripherin marks small-diameter unmyelinated C-fiber neurons in the DRG. http://purl.obolibrary.org/obo/CL_4033181 dorsal root ganglion Piezo2 neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A sensory neuron that has the soma located in the dorsal root ganglion and expresses the marker piezo-type mechanosensitive ion channel component 2 (Piezo2). Piezo2 is the primary mechanotransduction channel and is present in approximately 35% of TrkA-positive human DRG neurons. http://purl.obolibrary.org/obo/CL_4033182 dorsal root ganglion RET neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A sensory neuron that has the soma located in the dorsal root ganglion and expresses the marker proto-oncogene tyrosine-protein kinase receptor Ret (RET). RET is present in approximately 46% of TrkA-positive human DRG neurons and marks the non-peptidergic nociceptor population. http://purl.obolibrary.org/obo/CL_4033183 dorsal root ganglion SP neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A sensory neuron that has the soma located in the dorsal root ganglion and expresses the marker protachykinin-1 (substance P). This peptidergic nociceptor subpopulation is involved in pain signaling and neurogenic inflammation. http://purl.obolibrary.org/obo/CL_4033184 dorsal root ganglion TRPV1 neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A sensory neuron that has the soma located in the dorsal root ganglion and expresses the marker transient receptor potential cation channel subfamily V member 1 (TRPV1). TRPV1 is the canonical heat and capsaicin nociceptor marker and is present in approximately 54% of TrkA-positive human DRG neurons. http://purl.obolibrary.org/obo/CL_4079000 cervical dorsal root ganglion CGRP neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A peptidergic nociceptor whose soma is located in the cervical dorsal root ganglion, characterized by expression of calcitonin gene-related peptide (CGRP, encoded by CALCA). This small- to medium-diameter neuron belongs to the TrkA-positive peptidergic subpopulation and typically co-expresses substance P. It innervates peripheral tissues including skin and viscera, where it mediates neurogenic inflammation and nociceptive signalling through release of CGRP from peripheral terminals during tissue injury (Haberberger et al. 2019, PMID:31293388). In human DRG, CGRP-immunoreactive neurons represent a substantial proportion of nociceptors, comparable to the pattern observed in rodents (Rostock et al. 2018, PMID:29229553). http://purl.obolibrary.org/obo/CL_4079001 cervical dorsal root ganglion endothelin-1 neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A sensory neuron whose soma is located in the cervical dorsal root ganglion and that expresses endothelin-1 (EDN1). In rat DRG, EDN1 immunoreactivity has been detected in a subset of neuron somata (Giaid et al. 1989, PMID:2678100). Endothelin-1 acts as an endogenous pain mediator, sensitizing nociceptors through activation of ETA and ETB receptors, and these neurons are implicated in vascular pain signalling. EDN1-expressing DRG neurons have been characterized in rat; their prevalence and properties in human DRG remain to be systematically determined, as EDN1 is not yet represented in human DRG single-cell transcriptomic datasets. http://purl.obolibrary.org/obo/CL_4079002 cervical dorsal root ganglion Nav1.7 neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A nociceptor whose soma is located in the cervical dorsal root ganglion and that expresses the voltage-gated sodium channel Nav1.7 (encoded by SCN9A). This neuron is characterized by Nav1.7-dependent action potential initiation and amplification, which is essential for normal pain sensation in humans. Nav1.7 contributes approximately 50% of total sodium channel current in human DRG nociceptors (Chang et al. 2018, PMID:28424991). In human DRG, Nav1.7 immunoreactivity is detected in 54-57% of TrkA-positive neurons (Rostock et al. 2018, PMID:29229553). Human genetic evidence confirms Nav1.7 as necessary and sufficient for nociceptive function in these neurons. http://purl.obolibrary.org/obo/CL_4079003 cervical dorsal root ganglion Nav1.9 neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A nociceptor whose soma is located in the cervical dorsal root ganglion and that expresses the voltage-gated sodium channel Nav1.9 (encoded by SCN11A). This neuron is characterized by a persistent, tetrodotoxin-resistant sodium current that modulates resting membrane potential and amplifies subthreshold depolarizations, contributing to enhanced excitability during inflammation (Dib-Hajj et al. 2002, PMID:11972962). In human DRG, Nav1.9-immunoreactive neurons constitute approximately 26% of TrkA-positive neurons, a significantly higher proportion than the 12% observed in mouse (Rostock et al. 2018, PMID:29229553), suggesting species differences in inflammatory pain processing. http://purl.obolibrary.org/obo/CL_4079004 cervical dorsal root ganglion peripherin neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A small-diameter sensory neuron whose soma is located in the cervical dorsal root ganglion and that expresses peripherin (encoded by PRPH), a type III intermediate filament protein. This neuron is unmyelinated, conducts action potentials as a C-fiber, and encompasses nociceptive and thermoceptive functional subpopulations. In human DRG, peripherin-immunoreactive neurons are predominantly of small diameter (Chang et al. 2018, PMID:28424991), distinguishing them from large-diameter myelinated A-fiber neurons that instead express neurofilament heavy chain (Haberberger et al. 2019, PMID:31293388). In mice, peripherin similarly marks unmyelinated primary afferent neurons. http://purl.obolibrary.org/obo/CL_4079005 cervical dorsal root ganglion Piezo2 neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A mechanosensitive sensory neuron whose soma is located in the cervical dorsal root ganglion and that expresses the mechanically activated ion channel Piezo2 (encoded by PIEZO2). This neuron transduces mechanical stimuli and is involved in light touch perception and proprioception. In human DRG, Piezo2-immunoreactive neurons constitute approximately 35% of TrkA-positive neurons, compared to 26% in mouse (Rostock et al. 2018, PMID:29229553). This subpopulation includes both low-threshold mechanoreceptors mediating innocuous touch and a subset of mechanically sensitive nociceptors, reflecting the dual role of Piezo2 in somatosensation across species. http://purl.obolibrary.org/obo/CL_4079006 cervical dorsal root ganglion RET neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A non-peptidergic nociceptor whose soma is located in the cervical dorsal root ganglion and that expresses the receptor tyrosine kinase RET (encoded by RET). This neuron is distinguished from peptidergic nociceptors by its dependence on glial cell-derived neurotrophic factor family ligands rather than nerve growth factor, and in rodents it characteristically binds isolectin B4. In human DRG, RET-immunoreactive neurons constitute approximately 46% of TrkA-positive neurons, a significantly higher proportion than the 23% observed in mouse (Rostock et al. 2018, PMID:29229553), indicating an expanded non-peptidergic nociceptor compartment in humans. http://purl.obolibrary.org/obo/CL_4079007 cervical dorsal root ganglion substance P neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A peptidergic nociceptor whose soma is located in the cervical dorsal root ganglion and that expresses substance P, an 11-amino-acid neuropeptide cleaved from protachykinin-1 (encoded by TAC1). This small-diameter neuron frequently co-expresses CGRP and belongs to the TrkA-positive peptidergic population. Upon nociceptive activation, it releases substance P both centrally in the spinal cord dorsal horn and peripherally at sensory nerve terminals, mediating neurogenic inflammation through NK1 receptor signalling (Haberberger et al. 2019, PMID:31293388). Substance P-immunoreactive neurons have been consistently identified in human DRG by immunohistochemistry across multiple studies. http://purl.obolibrary.org/obo/CL_4079008 cervical dorsal root ganglion TRPV1 neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A polymodal nociceptor whose soma is located in the cervical dorsal root ganglion and that expresses the transient receptor potential vanilloid 1 channel (TRPV1, encoded by TRPV1). This neuron detects noxious heat above 43 degrees Celsius, protons, and endogenous lipid mediators, and is activated by capsaicin. In human DRG, TRPV1-immunoreactive neurons constitute approximately 54% of TrkA-positive neurons, significantly higher than the 35% observed in mouse (Rostock et al. 2018, PMID:29229553). These neurons are predominantly small-diameter nociceptors that innervate skin and visceral organs, where they function as primary detectors of thermal and chemical noxious stimuli. http://purl.obolibrary.org/obo/CL_4079010 intrinsic cardiac ganglion TH neuron http://purl.obolibrary.org/obo/CL_0000107 autonomic neuron A catecholaminergic neuron whose soma is located in an intrinsic cardiac ganglion and that expresses tyrosine hydroxylase (TH, encoded by TH), the rate-limiting enzyme in catecholamine biosynthesis. This neuron constitutes a minor subpopulation within the predominantly cholinergic parasympathetic intrinsic cardiac nervous system, identified in adult human cardiac ganglia by immunohistochemistry (Singh et al. 1999, PMID:9918529; Kawano et al. 2003, DOI:10.1007/s003800300005). It participates in local cardiac autonomic regulation, including modulation of heart rate and contractility. Its catecholaminergic phenotype distinguishes it from the majority cholinergic neurons of the same ganglia. http://purl.obolibrary.org/obo/CL_4079011 lumbar dorsal root ganglion CGRP neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A peptidergic nociceptor whose soma is located in the lumbar dorsal root ganglion, characterized by expression of calcitonin gene-related peptide (CGRP, encoded by CALCA). This small- to medium-diameter neuron belongs to the TrkA-positive peptidergic subpopulation and typically co-expresses substance P. It innervates peripheral tissues including skin and viscera, where it mediates neurogenic inflammation and nociceptive signalling through release of CGRP from peripheral terminals during tissue injury (Haberberger et al. 2019, PMID:31293388). In human DRG, CGRP-immunoreactive neurons represent a substantial proportion of nociceptors, comparable to the pattern observed in rodents (Rostock et al. 2018, PMID:29229553). http://purl.obolibrary.org/obo/CL_4079012 lumbar dorsal root ganglion endothelin-1 neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A sensory neuron whose soma is located in the lumbar dorsal root ganglion and that expresses endothelin-1 (EDN1). In rat DRG, EDN1 immunoreactivity has been detected in a subset of neuron somata (Giaid et al. 1989, PMID:2678100). Endothelin-1 acts as an endogenous pain mediator, sensitizing nociceptors through activation of ETA and ETB receptors, and these neurons are implicated in vascular pain signalling. EDN1-expressing DRG neurons have been characterized in rat; their prevalence and properties in human DRG remain to be systematically determined, as EDN1 is not yet represented in human DRG single-cell transcriptomic datasets. http://purl.obolibrary.org/obo/CL_4079013 lumbar dorsal root ganglion Nav1.7 neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A nociceptor whose soma is located in the lumbar dorsal root ganglion and that expresses the voltage-gated sodium channel Nav1.7 (encoded by SCN9A). This neuron is characterized by Nav1.7-dependent action potential initiation and amplification, which is essential for normal pain sensation in humans. Nav1.7 contributes approximately 50% of total sodium channel current in human DRG nociceptors (Chang et al. 2018, PMID:28424991). In human DRG, Nav1.7 immunoreactivity is detected in 54-57% of TrkA-positive neurons (Rostock et al. 2018, PMID:29229553). Human genetic evidence confirms Nav1.7 as necessary and sufficient for nociceptive function in these neurons. http://purl.obolibrary.org/obo/CL_4079014 lumbar dorsal root ganglion Nav1.9 neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A nociceptor whose soma is located in the lumbar dorsal root ganglion and that expresses the voltage-gated sodium channel Nav1.9 (encoded by SCN11A). This neuron is characterized by a persistent, tetrodotoxin-resistant sodium current that modulates resting membrane potential and amplifies subthreshold depolarizations, contributing to enhanced excitability during inflammation (Dib-Hajj et al. 2002, PMID:11972962). In human DRG, Nav1.9-immunoreactive neurons constitute approximately 26% of TrkA-positive neurons, a significantly higher proportion than the 12% observed in mouse (Rostock et al. 2018, PMID:29229553), suggesting species differences in inflammatory pain processing. http://purl.obolibrary.org/obo/CL_4079015 lumbar dorsal root ganglion peripherin neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A small-diameter sensory neuron whose soma is located in the lumbar dorsal root ganglion and that expresses peripherin (encoded by PRPH), a type III intermediate filament protein. This neuron is unmyelinated, conducts action potentials as a C-fiber, and encompasses nociceptive and thermoceptive functional subpopulations. In human DRG, peripherin-immunoreactive neurons are predominantly of small diameter (Chang et al. 2018, PMID:28424991), distinguishing them from large-diameter myelinated A-fiber neurons that instead express neurofilament heavy chain (Haberberger et al. 2019, PMID:31293388). In mice, peripherin similarly marks unmyelinated primary afferent neurons. http://purl.obolibrary.org/obo/CL_4079016 lumbar dorsal root ganglion Piezo2 neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A mechanosensitive sensory neuron whose soma is located in the lumbar dorsal root ganglion and that expresses the mechanically activated ion channel Piezo2 (encoded by PIEZO2). This neuron transduces mechanical stimuli and is involved in light touch perception and proprioception. In human DRG, Piezo2-immunoreactive neurons constitute approximately 35% of TrkA-positive neurons, compared to 26% in mouse (Rostock et al. 2018, PMID:29229553). This subpopulation includes both low-threshold mechanoreceptors mediating innocuous touch and a subset of mechanically sensitive nociceptors, reflecting the dual role of Piezo2 in somatosensation across species. http://purl.obolibrary.org/obo/CL_4079017 lumbar dorsal root ganglion RET neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A non-peptidergic nociceptor whose soma is located in the lumbar dorsal root ganglion and that expresses the receptor tyrosine kinase RET (encoded by RET). This neuron is distinguished from peptidergic nociceptors by its dependence on glial cell-derived neurotrophic factor family ligands rather than nerve growth factor, and in rodents it characteristically binds isolectin B4. In human DRG, RET-immunoreactive neurons constitute approximately 46% of TrkA-positive neurons, a significantly higher proportion than the 23% observed in mouse (Rostock et al. 2018, PMID:29229553), indicating an expanded non-peptidergic nociceptor compartment in humans. http://purl.obolibrary.org/obo/CL_4079018 lumbar dorsal root ganglion substance P neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A peptidergic nociceptor whose soma is located in the lumbar dorsal root ganglion and that expresses substance P, an 11-amino-acid neuropeptide cleaved from protachykinin-1 (encoded by TAC1). This small-diameter neuron frequently co-expresses CGRP and belongs to the TrkA-positive peptidergic population. Upon nociceptive activation, it releases substance P both centrally in the spinal cord dorsal horn and peripherally at sensory nerve terminals, mediating neurogenic inflammation through NK1 receptor signalling (Haberberger et al. 2019, PMID:31293388). Substance P-immunoreactive neurons have been consistently identified in human DRG by immunohistochemistry across multiple studies. http://purl.obolibrary.org/obo/CL_4079019 lumbar dorsal root ganglion TRPV1 neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A polymodal nociceptor whose soma is located in the lumbar dorsal root ganglion and that expresses the transient receptor potential vanilloid 1 channel (TRPV1, encoded by TRPV1). This neuron detects noxious heat above 43 degrees Celsius, protons, and endogenous lipid mediators, and is activated by capsaicin. In human DRG, TRPV1-immunoreactive neurons constitute approximately 54% of TrkA-positive neurons, significantly higher than the 35% observed in mouse (Rostock et al. 2018, PMID:29229553). These neurons are predominantly small-diameter nociceptors that innervate skin and visceral organs, where they function as primary detectors of thermal and chemical noxious stimuli. http://purl.obolibrary.org/obo/CL_4079020 sacral dorsal root ganglion CGRP neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A peptidergic nociceptor whose soma is located in the sacral dorsal root ganglion, characterized by expression of calcitonin gene-related peptide (CGRP, encoded by CALCA). This small- to medium-diameter neuron belongs to the TrkA-positive peptidergic subpopulation and typically co-expresses substance P. It innervates peripheral tissues including skin and viscera, where it mediates neurogenic inflammation and nociceptive signalling through release of CGRP from peripheral terminals during tissue injury (Haberberger et al. 2019, PMID:31293388). In human DRG, CGRP-immunoreactive neurons represent a substantial proportion of nociceptors, comparable to the pattern observed in rodents (Rostock et al. 2018, PMID:29229553). http://purl.obolibrary.org/obo/CL_4079021 sacral dorsal root ganglion endothelin-1 neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A sensory neuron whose soma is located in the sacral dorsal root ganglion and that expresses endothelin-1 (EDN1). In rat DRG, EDN1 immunoreactivity has been detected in a subset of neuron somata (Giaid et al. 1989, PMID:2678100). Endothelin-1 acts as an endogenous pain mediator, sensitizing nociceptors through activation of ETA and ETB receptors, and these neurons are implicated in vascular pain signalling. EDN1-expressing DRG neurons have been characterized in rat; their prevalence and properties in human DRG remain to be systematically determined, as EDN1 is not yet represented in human DRG single-cell transcriptomic datasets. http://purl.obolibrary.org/obo/CL_4079022 sacral dorsal root ganglion Nav1.7 neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A nociceptor whose soma is located in the sacral dorsal root ganglion and that expresses the voltage-gated sodium channel Nav1.7 (encoded by SCN9A). This neuron is characterized by Nav1.7-dependent action potential initiation and amplification, which is essential for normal pain sensation in humans. Nav1.7 contributes approximately 50% of total sodium channel current in human DRG nociceptors (Chang et al. 2018, PMID:28424991). In human DRG, Nav1.7 immunoreactivity is detected in 54-57% of TrkA-positive neurons (Rostock et al. 2018, PMID:29229553). Human genetic evidence confirms Nav1.7 as necessary and sufficient for nociceptive function in these neurons. http://purl.obolibrary.org/obo/CL_4079023 sacral dorsal root ganglion Nav1.9 neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A nociceptor whose soma is located in the sacral dorsal root ganglion and that expresses the voltage-gated sodium channel Nav1.9 (encoded by SCN11A). This neuron is characterized by a persistent, tetrodotoxin-resistant sodium current that modulates resting membrane potential and amplifies subthreshold depolarizations, contributing to enhanced excitability during inflammation (Dib-Hajj et al. 2002, PMID:11972962). In human DRG, Nav1.9-immunoreactive neurons constitute approximately 26% of TrkA-positive neurons, a significantly higher proportion than the 12% observed in mouse (Rostock et al. 2018, PMID:29229553), suggesting species differences in inflammatory pain processing. http://purl.obolibrary.org/obo/CL_4079024 sacral dorsal root ganglion peripherin neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A small-diameter sensory neuron whose soma is located in the sacral dorsal root ganglion and that expresses peripherin (encoded by PRPH), a type III intermediate filament protein. This neuron is unmyelinated, conducts action potentials as a C-fiber, and encompasses nociceptive and thermoceptive functional subpopulations. In human DRG, peripherin-immunoreactive neurons are predominantly of small diameter (Chang et al. 2018, PMID:28424991), distinguishing them from large-diameter myelinated A-fiber neurons that instead express neurofilament heavy chain (Haberberger et al. 2019, PMID:31293388). In mice, peripherin similarly marks unmyelinated primary afferent neurons. http://purl.obolibrary.org/obo/CL_4079025 sacral dorsal root ganglion Piezo2 neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A mechanosensitive sensory neuron whose soma is located in the sacral dorsal root ganglion and that expresses the mechanically activated ion channel Piezo2 (encoded by PIEZO2). This neuron transduces mechanical stimuli and is involved in light touch perception and proprioception. In human DRG, Piezo2-immunoreactive neurons constitute approximately 35% of TrkA-positive neurons, compared to 26% in mouse (Rostock et al. 2018, PMID:29229553). This subpopulation includes both low-threshold mechanoreceptors mediating innocuous touch and a subset of mechanically sensitive nociceptors, reflecting the dual role of Piezo2 in somatosensation across species. http://purl.obolibrary.org/obo/CL_4079026 sacral dorsal root ganglion RET neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A non-peptidergic nociceptor whose soma is located in the sacral dorsal root ganglion and that expresses the receptor tyrosine kinase RET (encoded by RET). This neuron is distinguished from peptidergic nociceptors by its dependence on glial cell-derived neurotrophic factor family ligands rather than nerve growth factor, and in rodents it characteristically binds isolectin B4. In human DRG, RET-immunoreactive neurons constitute approximately 46% of TrkA-positive neurons, a significantly higher proportion than the 23% observed in mouse (Rostock et al. 2018, PMID:29229553), indicating an expanded non-peptidergic nociceptor compartment in humans. http://purl.obolibrary.org/obo/CL_4079027 sacral dorsal root ganglion substance P neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A peptidergic nociceptor whose soma is located in the sacral dorsal root ganglion and that expresses substance P, an 11-amino-acid neuropeptide cleaved from protachykinin-1 (encoded by TAC1). This small-diameter neuron frequently co-expresses CGRP and belongs to the TrkA-positive peptidergic population. Upon nociceptive activation, it releases substance P both centrally in the spinal cord dorsal horn and peripherally at sensory nerve terminals, mediating neurogenic inflammation through NK1 receptor signalling (Haberberger et al. 2019, PMID:31293388). Substance P-immunoreactive neurons have been consistently identified in human DRG by immunohistochemistry across multiple studies. http://purl.obolibrary.org/obo/CL_4079028 sacral dorsal root ganglion TRPV1 neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A polymodal nociceptor whose soma is located in the sacral dorsal root ganglion and that expresses the transient receptor potential vanilloid 1 channel (TRPV1, encoded by TRPV1). This neuron detects noxious heat above 43 degrees Celsius, protons, and endogenous lipid mediators, and is activated by capsaicin. In human DRG, TRPV1-immunoreactive neurons constitute approximately 54% of TrkA-positive neurons, significantly higher than the 35% observed in mouse (Rostock et al. 2018, PMID:29229553). These neurons are predominantly small-diameter nociceptors that innervate skin and visceral organs, where they function as primary detectors of thermal and chemical noxious stimuli. http://purl.obolibrary.org/obo/CL_4079029 thoracic dorsal root ganglion CGRP neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A peptidergic nociceptor whose soma is located in the thoracic dorsal root ganglion, characterized by expression of calcitonin gene-related peptide (CGRP, encoded by CALCA). This small- to medium-diameter neuron belongs to the TrkA-positive peptidergic subpopulation and typically co-expresses substance P. It innervates peripheral tissues including skin and viscera, where it mediates neurogenic inflammation and nociceptive signalling through release of CGRP from peripheral terminals during tissue injury (Haberberger et al. 2019, PMID:31293388). In human DRG, CGRP-immunoreactive neurons represent a substantial proportion of nociceptors, comparable to the pattern observed in rodents (Rostock et al. 2018, PMID:29229553). http://purl.obolibrary.org/obo/CL_4079030 thoracic dorsal root ganglion endothelin-1 neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A sensory neuron whose soma is located in the thoracic dorsal root ganglion and that expresses endothelin-1 (EDN1). In rat DRG, EDN1 immunoreactivity has been detected in a subset of neuron somata (Giaid et al. 1989, PMID:2678100). Endothelin-1 acts as an endogenous pain mediator, sensitizing nociceptors through activation of ETA and ETB receptors, and these neurons are implicated in vascular pain signalling. EDN1-expressing DRG neurons have been characterized in rat; their prevalence and properties in human DRG remain to be systematically determined, as EDN1 is not yet represented in human DRG single-cell transcriptomic datasets. http://purl.obolibrary.org/obo/CL_4079031 thoracic dorsal root ganglion Nav1.7 neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A nociceptor whose soma is located in the thoracic dorsal root ganglion and that expresses the voltage-gated sodium channel Nav1.7 (encoded by SCN9A). This neuron is characterized by Nav1.7-dependent action potential initiation and amplification, which is essential for normal pain sensation in humans. Nav1.7 contributes approximately 50% of total sodium channel current in human DRG nociceptors (Chang et al. 2018, PMID:28424991). In human DRG, Nav1.7 immunoreactivity is detected in 54-57% of TrkA-positive neurons (Rostock et al. 2018, PMID:29229553). Human genetic evidence confirms Nav1.7 as necessary and sufficient for nociceptive function in these neurons. http://purl.obolibrary.org/obo/CL_4079032 thoracic dorsal root ganglion Nav1.9 neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A nociceptor whose soma is located in the thoracic dorsal root ganglion and that expresses the voltage-gated sodium channel Nav1.9 (encoded by SCN11A). This neuron is characterized by a persistent, tetrodotoxin-resistant sodium current that modulates resting membrane potential and amplifies subthreshold depolarizations, contributing to enhanced excitability during inflammation (Dib-Hajj et al. 2002, PMID:11972962). In human DRG, Nav1.9-immunoreactive neurons constitute approximately 26% of TrkA-positive neurons, a significantly higher proportion than the 12% observed in mouse (Rostock et al. 2018, PMID:29229553), suggesting species differences in inflammatory pain processing. http://purl.obolibrary.org/obo/CL_4079033 thoracic dorsal root ganglion peripherin neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A small-diameter sensory neuron whose soma is located in the thoracic dorsal root ganglion and that expresses peripherin (encoded by PRPH), a type III intermediate filament protein. This neuron is unmyelinated, conducts action potentials as a C-fiber, and encompasses nociceptive and thermoceptive functional subpopulations. In human DRG, peripherin-immunoreactive neurons are predominantly of small diameter (Chang et al. 2018, PMID:28424991), distinguishing them from large-diameter myelinated A-fiber neurons that instead express neurofilament heavy chain (Haberberger et al. 2019, PMID:31293388). In mice, peripherin similarly marks unmyelinated primary afferent neurons. http://purl.obolibrary.org/obo/CL_4079034 thoracic dorsal root ganglion Piezo2 neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A mechanosensitive sensory neuron whose soma is located in the thoracic dorsal root ganglion and that expresses the mechanically activated ion channel Piezo2 (encoded by PIEZO2). This neuron transduces mechanical stimuli and is involved in light touch perception and proprioception. In human DRG, Piezo2-immunoreactive neurons constitute approximately 35% of TrkA-positive neurons, compared to 26% in mouse (Rostock et al. 2018, PMID:29229553). This subpopulation includes both low-threshold mechanoreceptors mediating innocuous touch and a subset of mechanically sensitive nociceptors, reflecting the dual role of Piezo2 in somatosensation across species. http://purl.obolibrary.org/obo/CL_4079035 thoracic dorsal root ganglion RET neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A non-peptidergic nociceptor whose soma is located in the thoracic dorsal root ganglion and that expresses the receptor tyrosine kinase RET (encoded by RET). This neuron is distinguished from peptidergic nociceptors by its dependence on glial cell-derived neurotrophic factor family ligands rather than nerve growth factor, and in rodents it characteristically binds isolectin B4. In human DRG, RET-immunoreactive neurons constitute approximately 46% of TrkA-positive neurons, a significantly higher proportion than the 23% observed in mouse (Rostock et al. 2018, PMID:29229553), indicating an expanded non-peptidergic nociceptor compartment in humans. http://purl.obolibrary.org/obo/CL_4079036 thoracic dorsal root ganglion substance P neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A peptidergic nociceptor whose soma is located in the thoracic dorsal root ganglion and that expresses substance P, an 11-amino-acid neuropeptide cleaved from protachykinin-1 (encoded by TAC1). This small-diameter neuron frequently co-expresses CGRP and belongs to the TrkA-positive peptidergic population. Upon nociceptive activation, it releases substance P both centrally in the spinal cord dorsal horn and peripherally at sensory nerve terminals, mediating neurogenic inflammation through NK1 receptor signalling (Haberberger et al. 2019, PMID:31293388). Substance P-immunoreactive neurons have been consistently identified in human DRG by immunohistochemistry across multiple studies. http://purl.obolibrary.org/obo/CL_4079037 thoracic dorsal root ganglion TRPV1 neuron http://purl.obolibrary.org/obo/CL_1001451 sensory neuron of dorsal root ganglion A polymodal nociceptor whose soma is located in the thoracic dorsal root ganglion and that expresses the transient receptor potential vanilloid 1 channel (TRPV1, encoded by TRPV1). This neuron detects noxious heat above 43 degrees Celsius, protons, and endogenous lipid mediators, and is activated by capsaicin. In human DRG, TRPV1-immunoreactive neurons constitute approximately 54% of TrkA-positive neurons, significantly higher than the 35% observed in mouse (Rostock et al. 2018, PMID:29229553). These neurons are predominantly small-diameter nociceptors that innervate skin and visceral organs, where they function as primary detectors of thermal and chemical noxious stimuli. http://purl.obolibrary.org/obo/UBERON_0035005 preputial swelling of male http://purl.obolibrary.org/obo/UBERON_0035004 preputial swelling http://purl.obolibrary.org/obo/NCBITaxon_55879 Rhabditoidea http://purl.obolibrary.org/obo/NCBITaxon_2301119 Rhabditomorpha https://purl.brain-bican.org/ontology/mbao/MBA_1000 extrapyramidal fiber systems https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions https://purl.brain-bican.org/ontology/mbao/MBA_796 Dopaminergic A13 group https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions https://purl.brain-bican.org/ontology/mbao/MBA_117 optic chiasm https://purl.brain-bican.org/ontology/mbao/MBA_1009 fiber tracts https://purl.brain-bican.org/ontology/dhbao/DHBA_10644 optic chiasm http://purl.obolibrary.org/obo/UBERON_0000959 optic chiasma http://purl.obolibrary.org/obo/UBERON_0037458 hair of neck http://purl.obolibrary.org/obo/UBERON_0001037 strand of hair http://purl.obolibrary.org/obo/UBERON_0037459 hair of limb http://purl.obolibrary.org/obo/UBERON_0001037 strand of hair http://purl.obolibrary.org/obo/UBERON_0036268 pelvic vein http://purl.obolibrary.org/obo/UBERON_0001638 vein http://purl.obolibrary.org/obo/UBERON_0039228 sigmoid vein http://purl.obolibrary.org/obo/UBERON_0001638 vein https://purl.brain-bican.org/ontology/dhbao/DHBA_12139 temporal lobe http://purl.obolibrary.org/obo/UBERON_0001871 temporal lobe https://purl.brain-bican.org/ontology/mbao/MBA_567 Cerebrum https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions https://purl.brain-bican.org/ontology/dhbao/DHBA_10158 telencephalon http://purl.obolibrary.org/obo/UBERON_0001893 telencephalon https://purl.brain-bican.org/ontology/mbao/MBA_1129 Interbrain https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions https://purl.brain-bican.org/ontology/dhbao/DHBA_10389 diencephalon http://purl.obolibrary.org/obo/UBERON_0001894 diencephalon https://purl.brain-bican.org/ontology/dhbao/DHBA_10460 pineal body http://purl.obolibrary.org/obo/UBERON_0001905 pineal body https://purl.brain-bican.org/ontology/mbao/MBA_125 optic tract https://purl.brain-bican.org/ontology/mbao/MBA_1009 fiber tracts https://purl.brain-bican.org/ontology/dhbao/DHBA_10589 optic tract http://purl.obolibrary.org/obo/UBERON_0001908 optic tract https://purl.brain-bican.org/ontology/mbao/MBA_512 Cerebellum https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions https://purl.brain-bican.org/ontology/dhbao/DHBA_10656 cerebellum http://purl.obolibrary.org/obo/UBERON_0002037 cerebellum https://purl.brain-bican.org/ontology/mbao/MBA_81 lateral ventricle http://purl.obolibrary.org/obo/UBERON_0002285 telencephalic ventricle https://purl.brain-bican.org/ontology/dhbao/DHBA_10596 lateral ventricles http://purl.obolibrary.org/obo/UBERON_0002285 telencephalic ventricle https://purl.brain-bican.org/ontology/mbao/MBA_129 third ventricle http://purl.obolibrary.org/obo/UBERON_0002286 third ventricle https://purl.brain-bican.org/ontology/dhbao/DHBA_10602 third ventricle http://purl.obolibrary.org/obo/UBERON_0002286 third ventricle https://purl.brain-bican.org/ontology/dhbao/DHBA_10332 basal nuclei (basal ganglia) https://purl.brain-bican.org/ontology/dhbao/DHBA_10157 gray matter of forebrain https://purl.brain-bican.org/ontology/dhbao/DHBA_10658 cerebellar vermis http://purl.obolibrary.org/obo/UBERON_0004720 cerebellar vermis http://purl.obolibrary.org/obo/PR_000044780 leukocyte immunoglobulin-like receptor subfamily member http://purl.obolibrary.org/obo/PR_000000001 protein http://purl.obolibrary.org/obo/CL_0010013 type I pinealocyte http://purl.obolibrary.org/obo/CL_0000652 pinealocyte http://purl.obolibrary.org/obo/CL_0010014 type II pinealocyte http://purl.obolibrary.org/obo/CL_0000652 pinealocyte http://purl.obolibrary.org/obo/CL_4023032 ON retinal ganglion cell http://purl.obolibrary.org/obo/CL_0000740 retinal ganglion cell https://purl.brain-bican.org/ontology/dhbao/DHBA_10505 pituitary body http://purl.obolibrary.org/obo/UBERON_0000007 pituitary gland http://purl.obolibrary.org/obo/UBERON_0035764 pulmonary lymph node http://purl.obolibrary.org/obo/UBERON_0000029 lymph node https://purl.brain-bican.org/ontology/mbao/MBA_304325711 retina http://purl.obolibrary.org/obo/UBERON_0000966 retina http://purl.obolibrary.org/obo/UBERON_0039261 pancreatic artery http://purl.obolibrary.org/obo/UBERON_0001637 artery http://purl.obolibrary.org/obo/UBERON_0035039 rectal artery http://purl.obolibrary.org/obo/UBERON_0001637 artery https://purl.brain-bican.org/ontology/dhbao/DHBA_12131 parietal lobe http://purl.obolibrary.org/obo/UBERON_0001872 parietal lobe http://purl.obolibrary.org/obo/UBERON_0035767 intrapulmonary bronchus http://purl.obolibrary.org/obo/UBERON_0002185 bronchus https://purl.brain-bican.org/ontology/dhbao/DHBA_12890 spinal cord http://purl.obolibrary.org/obo/UBERON_0002240 spinal cord https://purl.brain-bican.org/ontology/mbao/MBA_343 Brain stem https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions https://purl.brain-bican.org/ontology/mbao/MBA_776 corpus callosum https://purl.brain-bican.org/ontology/mbao/MBA_1009 fiber tracts https://purl.brain-bican.org/ontology/dhbao/DHBA_10561 corpus callosum http://purl.obolibrary.org/obo/UBERON_0002336 corpus callosum https://purl.brain-bican.org/ontology/dhbao/DHBA_12113 frontal lobe http://purl.obolibrary.org/obo/UBERON_0016525 frontal lobe https://purl.brain-bican.org/ontology/dhbao/DHBA_12682 intermediate (mantle) zone of hindbrain http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure http://purl.obolibrary.org/obo/NCBITaxon_9685 Felis catus http://purl.obolibrary.org/obo/NCBITaxon_9682 Felis http://purl.obolibrary.org/obo/NCBITaxon_142796 Eumycetozoa http://purl.obolibrary.org/obo/NCBITaxon_2605435 Evosea https://purl.brain-bican.org/ontology/mbao/MBA_500 Somatomotor areas https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions http://purl.obolibrary.org/obo/NCBITaxon_6236 Rhabditida http://purl.obolibrary.org/obo/NCBITaxon_119089 Chromadorea http://purl.obolibrary.org/obo/NCBITaxon_554915 Amoebozoa http://purl.obolibrary.org/obo/NCBITaxon_2759 Eukaryota http://purl.obolibrary.org/obo/NCBITaxon_33554 Carnivora http://purl.obolibrary.org/obo/NCBITaxon_314145 Laurasiatheria http://purl.obolibrary.org/obo/NCBITaxon_9787 Perissodactyla http://purl.obolibrary.org/obo/NCBITaxon_314145 Laurasiatheria http://purl.obolibrary.org/obo/NCBITaxon_9443 Primates http://purl.obolibrary.org/obo/NCBITaxon_314146 Euarchontoglires http://purl.obolibrary.org/obo/NCBITaxon_9975 Lagomorpha http://purl.obolibrary.org/obo/NCBITaxon_314147 Glires http://purl.obolibrary.org/obo/NCBITaxon_2697495 Spiralia http://purl.obolibrary.org/obo/NCBITaxon_33317 Protostomia http://purl.obolibrary.org/obo/NCBITaxon_7586 Echinodermata http://purl.obolibrary.org/obo/NCBITaxon_33511 Deuterostomia http://purl.obolibrary.org/obo/NCBITaxon_147554 Schizosaccharomycetes http://purl.obolibrary.org/obo/NCBITaxon_451866 Taphrinomycotina http://purl.obolibrary.org/obo/NCBITaxon_6073 Cnidaria http://purl.obolibrary.org/obo/NCBITaxon_6072 Eumetazoa http://purl.obolibrary.org/obo/UBERON_0036553 wall of synovial tendon sheath http://purl.obolibrary.org/obo/UBERON_0000060 anatomical wall https://purl.brain-bican.org/ontology/mbao/MBA_1099 fornix system https://purl.brain-bican.org/ontology/mbao/MBA_1009 fiber tracts https://purl.brain-bican.org/ontology/dhbao/DHBA_10576 fornix http://purl.obolibrary.org/obo/UBERON_0000052 fornix of brain http://purl.obolibrary.org/obo/UBERON_0035074 duct of apocrine sweat gland http://purl.obolibrary.org/obo/UBERON_0000058 duct http://purl.obolibrary.org/obo/UBERON_0035050 excretory duct http://purl.obolibrary.org/obo/UBERON_0000058 duct http://purl.obolibrary.org/obo/UBERON_0036441 wall of fallopian tube http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure http://purl.obolibrary.org/obo/UBERON_0036521 wall of urethra http://purl.obolibrary.org/obo/UBERON_0000060 anatomical wall http://purl.obolibrary.org/obo/UBERON_0036523 wall of vagina http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure http://purl.obolibrary.org/obo/UBERON_0036658 wall of central canal of spinal cord http://purl.obolibrary.org/obo/UBERON_0005358 ventricle of nervous system http://purl.obolibrary.org/obo/UBERON_0036661 wall of ventricular system of brain http://purl.obolibrary.org/obo/UBERON_0005358 ventricle of nervous system http://purl.obolibrary.org/obo/UBERON_0036925 wall of eyeball http://purl.obolibrary.org/obo/UBERON_0000060 anatomical wall http://purl.obolibrary.org/obo/UBERON_0036990 wall of pharyngotympanic tube http://purl.obolibrary.org/obo/UBERON_0000060 anatomical wall http://purl.obolibrary.org/obo/UBERON_0037089 wall of orbit http://purl.obolibrary.org/obo/UBERON_0000075 subdivision of skeletal system http://purl.obolibrary.org/obo/UBERON_0037191 wall of membranous labyrinth http://purl.obolibrary.org/obo/UBERON_0000060 anatomical wall http://purl.obolibrary.org/obo/UBERON_0037237 wall of lacrimal duct http://purl.obolibrary.org/obo/UBERON_0000060 anatomical wall http://purl.obolibrary.org/obo/UBERON_0035965 wall of blood vessel http://purl.obolibrary.org/obo/UBERON_0000060 anatomical wall http://purl.obolibrary.org/obo/UBERON_0034944 zone of organ http://purl.obolibrary.org/obo/UBERON_0000064 organ part https://purl.brain-bican.org/ontology/mbao/MBA_1009 fiber tracts http://purl.obolibrary.org/obo/UBERON_0011215 central nervous system cell part cluster https://purl.brain-bican.org/ontology/dhbao/DHBA_12420 facial nucleus http://purl.obolibrary.org/obo/UBERON_0000127 facial nucleus http://purl.obolibrary.org/obo/UBERON_0036253 orifice of skull http://purl.obolibrary.org/obo/UBERON_0000161 orifice https://purl.brain-bican.org/ontology/dhbao/DHBA_10295 dentate area (dentate gyrus) http://purl.obolibrary.org/obo/UBERON_0001885 dentate gyrus of hippocampal formation http://purl.obolibrary.org/obo/UBERON_0039175 subarachnoid space of brain http://purl.obolibrary.org/obo/UBERON_0000315 subarachnoid space http://purl.obolibrary.org/obo/UBERON_0039176 subarachnoid space of spinal cord http://purl.obolibrary.org/obo/UBERON_0000315 subarachnoid space http://purl.obolibrary.org/obo/UBERON_0036328 wall of coronary artery http://purl.obolibrary.org/obo/UBERON_0037144 wall of heart http://purl.obolibrary.org/obo/UBERON_0036351 wall of brachiocephalic artery http://purl.obolibrary.org/obo/UBERON_0000415 artery wall http://purl.obolibrary.org/obo/UBERON_0036352 wall of subclavian artery http://purl.obolibrary.org/obo/UBERON_0000415 artery wall http://purl.obolibrary.org/obo/UBERON_0036422 wall of pulmonary artery http://purl.obolibrary.org/obo/UBERON_0000415 artery wall http://purl.obolibrary.org/obo/UBERON_0037094 wall of common carotid artery http://purl.obolibrary.org/obo/UBERON_0000415 artery wall https://purl.brain-bican.org/ontology/mbao/MBA_158 posterior commissure https://purl.brain-bican.org/ontology/mbao/MBA_1009 fiber tracts https://purl.brain-bican.org/ontology/dhbao/DHBA_10567 posterior commissure http://purl.obolibrary.org/obo/UBERON_0000936 posterior commissure https://purl.brain-bican.org/ontology/mbao/MBA_848 optic nerve https://purl.brain-bican.org/ontology/mbao/MBA_1009 fiber tracts https://purl.brain-bican.org/ontology/dhbao/DHBA_15544 optic nerve http://purl.obolibrary.org/obo/UBERON_0000941 cranial nerve II https://purl.brain-bican.org/ontology/mbao/MBA_688 Cerebral cortex http://purl.obolibrary.org/obo/UBERON_0000956 cerebral cortex https://purl.brain-bican.org/ontology/dhbao/DHBA_10159 cerebral cortex http://purl.obolibrary.org/obo/UBERON_0000956 cerebral cortex https://purl.brain-bican.org/ontology/mbao/MBA_771 Pons https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions https://purl.brain-bican.org/ontology/dhbao/DHBA_10661 pons http://purl.obolibrary.org/obo/UBERON_0000988 pons https://purl.brain-bican.org/ontology/dhbao/DHBA_10154 neural tube http://purl.obolibrary.org/obo/UBERON_0001049 neural tube https://purl.brain-bican.org/ontology/mbao/MBA_1049 Flocculus https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions http://purl.obolibrary.org/obo/UBERON_0036337 wall of appendix http://purl.obolibrary.org/obo/UBERON_0001169 wall of large intestine http://purl.obolibrary.org/obo/UBERON_0036362 wall of anal canal http://purl.obolibrary.org/obo/UBERON_0001169 wall of large intestine http://purl.obolibrary.org/obo/UBERON_0034997 renal medulla loop of Henle http://purl.obolibrary.org/obo/UBERON_0001288 loop of Henle https://purl.brain-bican.org/ontology/mbao/MBA_985 Primary motor area https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions https://purl.brain-bican.org/ontology/dhbao/DHBA_10162 posterior frontal cortex (motor cortex) http://purl.obolibrary.org/obo/UBERON_0001384 primary motor cortex https://purl.brain-bican.org/ontology/mbao/MBA_35 Oculomotor nucleus http://purl.obolibrary.org/obo/UBERON_0001715 oculomotor nuclear complex https://purl.brain-bican.org/ontology/dhbao/DHBA_12198 oculomotor nucleus https://purl.brain-bican.org/ontology/dhbao/DHBA_10649 gray matter of midbrain https://purl.brain-bican.org/ontology/dhbao/DHBA_10161 frontal neocortex https://purl.brain-bican.org/ontology/dhbao/DHBA_10157 gray matter of forebrain https://purl.brain-bican.org/ontology/dhbao/DHBA_10334 caudate nucleus http://purl.obolibrary.org/obo/UBERON_0001873 caudate nucleus https://purl.brain-bican.org/ontology/dhbao/DHBA_10338 putamen http://purl.obolibrary.org/obo/UBERON_0001874 putamen https://purl.brain-bican.org/ontology/dhbao/DHBA_10342 globus pallidus http://purl.obolibrary.org/obo/UBERON_0001875 globus pallidus https://purl.brain-bican.org/ontology/dhbao/DHBA_10361 amygdaloid complex https://purl.brain-bican.org/ontology/dhbao/DHBA_10332 basal nuclei (basal ganglia) https://purl.brain-bican.org/ontology/mbao/MBA_564 Medial septal nucleus http://purl.obolibrary.org/obo/UBERON_0001877 medial septal nucleus https://purl.brain-bican.org/ontology/dhbao/DHBA_10351 medial septal nucleus http://purl.obolibrary.org/obo/UBERON_0001877 medial septal nucleus https://purl.brain-bican.org/ontology/mbao/MBA_596 Diagonal band nucleus http://purl.obolibrary.org/obo/UBERON_0001879 nucleus of diagonal band https://purl.brain-bican.org/ontology/dhbao/DHBA_10354 nucleus of diagonal band http://purl.obolibrary.org/obo/UBERON_0001879 nucleus of diagonal band https://purl.brain-bican.org/ontology/mbao/MBA_481 Islands of Calleja http://purl.obolibrary.org/obo/UBERON_0001881 island of Calleja https://purl.brain-bican.org/ontology/dhbao/DHBA_10358 islands of Calleja http://purl.obolibrary.org/obo/UBERON_0001881 island of Calleja https://purl.brain-bican.org/ontology/mbao/MBA_56 Nucleus accumbens http://purl.obolibrary.org/obo/UBERON_0001882 nucleus accumbens https://purl.brain-bican.org/ontology/dhbao/DHBA_10339 nucleus accumbens http://purl.obolibrary.org/obo/UBERON_0001882 nucleus accumbens https://purl.brain-bican.org/ontology/mbao/MBA_754 Olfactory tubercle http://purl.obolibrary.org/obo/UBERON_0001883 olfactory tubercle https://purl.brain-bican.org/ontology/dhbao/DHBA_10310 olfactory tubercle http://purl.obolibrary.org/obo/UBERON_0001883 olfactory tubercle https://purl.brain-bican.org/ontology/mbao/MBA_726 Dentate gyrus https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions https://purl.brain-bican.org/ontology/mbao/MBA_665 lateral olfactory tract, body https://purl.brain-bican.org/ontology/mbao/MBA_1009 fiber tracts https://purl.brain-bican.org/ontology/dhbao/DHBA_12075 lateral olfactory stria https://purl.brain-bican.org/ontology/dhbao/DHBA_12073 olfactory tract https://purl.brain-bican.org/ontology/dhbao/DHBA_10156 forebrain (prosencephalon) http://purl.obolibrary.org/obo/UBERON_0001890 forebrain https://purl.brain-bican.org/ontology/mbao/MBA_313 Midbrain https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions https://purl.brain-bican.org/ontology/dhbao/DHBA_10648 midbrain (mesencephalon) http://purl.obolibrary.org/obo/UBERON_0001891 midbrain https://purl.brain-bican.org/ontology/dhbao/DHBA_12664 hindbrain neuromeres http://purl.obolibrary.org/obo/UBERON_0004733 segmental subdivision of hindbrain https://purl.brain-bican.org/ontology/dhbao/DHBA_10655 metencephalon http://purl.obolibrary.org/obo/UBERON_0004731 neuromere https://purl.brain-bican.org/ontology/mbao/MBA_354 Medulla http://purl.obolibrary.org/obo/UBERON_0001896 medulla oblongata https://purl.brain-bican.org/ontology/mbao/MBA_549 Thalamus https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions https://purl.brain-bican.org/ontology/dhbao/DHBA_10390 thalamus http://purl.obolibrary.org/obo/UBERON_0001897 dorsal plus ventral thalamus https://purl.brain-bican.org/ontology/mbao/MBA_1097 Hypothalamus https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions https://purl.brain-bican.org/ontology/dhbao/DHBA_10467 hypothalamus http://purl.obolibrary.org/obo/UBERON_0001898 hypothalamus https://purl.brain-bican.org/ontology/mbao/MBA_958 Epithalamus https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions https://purl.brain-bican.org/ontology/dhbao/DHBA_10451 epithalamus http://purl.obolibrary.org/obo/UBERON_0001899 epithalamus https://purl.brain-bican.org/ontology/dhbao/DHBA_10461 ventral thalamus http://purl.obolibrary.org/obo/UBERON_0001900 ventral thalamus https://purl.brain-bican.org/ontology/mbao/MBA_470 Subthalamic nucleus http://purl.obolibrary.org/obo/UBERON_0006568 hypothalamic nucleus https://purl.brain-bican.org/ontology/dhbao/DHBA_10466 subthalamic nucleus http://purl.obolibrary.org/obo/UBERON_0001906 subthalamic nucleus https://purl.brain-bican.org/ontology/mbao/MBA_797 Zona incerta http://purl.obolibrary.org/obo/UBERON_0006568 hypothalamic nucleus https://purl.brain-bican.org/ontology/dhbao/DHBA_10463 zona incerta http://purl.obolibrary.org/obo/UBERON_0001907 zona incerta https://purl.brain-bican.org/ontology/dhbao/DHBA_10429 lateral geniculate nucleus https://purl.brain-bican.org/ontology/dhbao/DHBA_10440 posterior nucleus of thalamus https://purl.brain-bican.org/ontology/mbao/MBA_38 Paraventricular hypothalamic nucleus http://purl.obolibrary.org/obo/UBERON_0006331 brainstem nucleus https://purl.brain-bican.org/ontology/dhbao/DHBA_10476 paraventricular nucleus of hypothalamus http://purl.obolibrary.org/obo/UBERON_0001930 paraventricular nucleus of hypothalamus https://purl.brain-bican.org/ontology/mbao/MBA_223 Arcuate hypothalamic nucleus http://purl.obolibrary.org/obo/UBERON_0006331 brainstem nucleus https://purl.brain-bican.org/ontology/dhbao/DHBA_10492 arcuate nucleus of hypothalamus http://purl.obolibrary.org/obo/UBERON_0001932 arcuate nucleus of hypothalamus https://purl.brain-bican.org/ontology/dhbao/DHBA_12195 midbrain tegmentum http://purl.obolibrary.org/obo/UBERON_0001943 midbrain tegmentum https://purl.brain-bican.org/ontology/mbao/MBA_1100 Pretectal region http://purl.obolibrary.org/obo/UBERON_0019267 gray matter of midbrain https://purl.brain-bican.org/ontology/dhbao/DHBA_12181 pretectal region https://purl.brain-bican.org/ontology/dhbao/DHBA_10649 gray matter of midbrain https://purl.brain-bican.org/ontology/mbao/MBA_315 Isocortex https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions https://purl.brain-bican.org/ontology/dhbao/DHBA_10160 neocortex (isocortex) http://purl.obolibrary.org/obo/UBERON_0001950 neocortex https://purl.brain-bican.org/ontology/mbao/MBA_375 Ammon's horn https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions https://purl.brain-bican.org/ontology/dhbao/DHBA_10296 hippocampal proper http://purl.obolibrary.org/obo/UBERON_0001954 Ammon's horn http://purl.obolibrary.org/obo/UBERON_0036269 penis blood vessel http://purl.obolibrary.org/obo/UBERON_0001981 blood vessel https://purl.brain-bican.org/ontology/mbao/MBA_1065 Hindbrain https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions https://purl.brain-bican.org/ontology/dhbao/DHBA_10653 hindbrain (rhombencephalon) http://purl.obolibrary.org/obo/UBERON_0002028 hindbrain https://purl.brain-bican.org/ontology/mbao/MBA_286 Suprachiasmatic nucleus http://purl.obolibrary.org/obo/UBERON_0006331 brainstem nucleus https://purl.brain-bican.org/ontology/dhbao/DHBA_10480 suprachiasmatic nucleus http://purl.obolibrary.org/obo/UBERON_0002034 suprachiasmatic nucleus https://purl.brain-bican.org/ontology/dhbao/DHBA_12251 substantia nigra http://purl.obolibrary.org/obo/UBERON_0007414 nucleus of midbrain tegmentum https://purl.brain-bican.org/ontology/mbao/MBA_238 Nucleus raphe pontis http://purl.obolibrary.org/obo/UBERON_0002047 pontine raphe nucleus https://purl.brain-bican.org/ontology/dhbao/DHBA_12475 raphe pontis nucleus http://purl.obolibrary.org/obo/UBERON_0002047 pontine raphe nucleus http://purl.obolibrary.org/obo/UBERON_0036302 vasculature of central nervous system plus retina http://purl.obolibrary.org/obo/UBERON_0002049 vasculature https://purl.brain-bican.org/ontology/dhbao/DHBA_10508 marginal zone http://purl.obolibrary.org/obo/UBERON_0010403 brain marginal zone https://purl.brain-bican.org/ontology/dhbao/DHBA_10522 subplate zone http://purl.obolibrary.org/obo/UBERON_0004035 cortical subplate https://purl.brain-bican.org/ontology/mbao/MBA_398 Superior olivary complex http://purl.obolibrary.org/obo/UBERON_0002128 superior olivary complex https://purl.brain-bican.org/ontology/dhbao/DHBA_12462 superior olivary complex https://purl.brain-bican.org/ontology/dhbao/DHBA_10654 gray matter of the hindbrain https://purl.brain-bican.org/ontology/mbao/MBA_528 Cerebellar cortex http://purl.obolibrary.org/obo/UBERON_0002129 cerebellar cortex https://purl.brain-bican.org/ontology/dhbao/DHBA_10657 cerebellar cortex https://purl.brain-bican.org/ontology/dhbao/DHBA_10654 gray matter of the hindbrain https://purl.brain-bican.org/ontology/mbao/MBA_519 Cerebellar nuclei http://purl.obolibrary.org/obo/UBERON_0002130 cerebellar nuclear complex https://purl.brain-bican.org/ontology/dhbao/DHBA_10660 cerebellar deep nuclei https://purl.brain-bican.org/ontology/dhbao/DHBA_10654 gray matter of the hindbrain https://purl.brain-bican.org/ontology/mbao/MBA_599626923 Subcommissural organ https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions https://purl.brain-bican.org/ontology/dhbao/DHBA_12101 subcommissural organ http://purl.obolibrary.org/obo/UBERON_0002139 subcommissural organ https://purl.brain-bican.org/ontology/mbao/MBA_1052 Pedunculopontine nucleus https://purl.brain-bican.org/ontology/mbao/MBA_128 Midbrain reticular nucleus https://purl.brain-bican.org/ontology/dhbao/DHBA_12413 peduncular nucleus http://purl.obolibrary.org/obo/UBERON_0009662 hindbrain nucleus https://purl.brain-bican.org/ontology/mbao/MBA_147 Locus ceruleus https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions https://purl.brain-bican.org/ontology/dhbao/DHBA_12819 locus coeruleus http://purl.obolibrary.org/obo/UBERON_0002148 locus ceruleus https://purl.brain-bican.org/ontology/mbao/MBA_462 Superior salivatory nucleus http://purl.obolibrary.org/obo/UBERON_0002149 superior salivatory nucleus https://purl.brain-bican.org/ontology/dhbao/DHBA_12435 superior salivatory nucleus http://purl.obolibrary.org/obo/UBERON_0002149 superior salivatory nucleus https://purl.brain-bican.org/ontology/mbao/MBA_931 Pontine gray http://purl.obolibrary.org/obo/UBERON_0002151 pontine nuclear group https://purl.brain-bican.org/ontology/dhbao/DHBA_12406 pontine nucleus http://purl.obolibrary.org/obo/UBERON_0002151 pontine nuclear group https://purl.brain-bican.org/ontology/mbao/MBA_78 middle cerebellar peduncle https://purl.brain-bican.org/ontology/mbao/MBA_752 cerebellar peduncles https://purl.brain-bican.org/ontology/dhbao/DHBA_12768 middle cerebellar peduncle https://purl.brain-bican.org/ontology/dhbao/DHBA_10668 white matter of hindbrain https://purl.brain-bican.org/ontology/mbao/MBA_207 Area postrema https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions https://purl.brain-bican.org/ontology/dhbao/DHBA_12807 area postrema http://purl.obolibrary.org/obo/UBERON_0002162 area postrema https://purl.brain-bican.org/ontology/mbao/MBA_502 Subiculum https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions https://purl.brain-bican.org/ontology/dhbao/DHBA_10302 subiculum http://purl.obolibrary.org/obo/UBERON_0002191 subiculum https://purl.brain-bican.org/ontology/mbao/MBA_10671 Median eminence https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions https://purl.brain-bican.org/ontology/dhbao/DHBA_13338 median eminence http://purl.obolibrary.org/obo/UBERON_0002197 median eminence of neurohypophysis https://purl.brain-bican.org/ontology/mbao/MBA_108 choroid plexus http://purl.obolibrary.org/obo/UBERON_0002307 choroid plexus of lateral ventricle https://purl.brain-bican.org/ontology/dhbao/DHBA_10601 choroid plexus of lateral ventricle http://purl.obolibrary.org/obo/UBERON_0002307 choroid plexus of lateral ventricle https://purl.brain-bican.org/ontology/dhbao/DHBA_12808 choroid plexus of the fourth ventricle http://purl.obolibrary.org/obo/UBERON_0002290 choroid plexus of fourth ventricle https://purl.brain-bican.org/ontology/mbao/MBA_331 Mammillary body http://purl.obolibrary.org/obo/UBERON_0002206 mammillary body https://purl.brain-bican.org/ontology/dhbao/DHBA_15546 mammillary body http://purl.obolibrary.org/obo/UBERON_0002206 mammillary body https://purl.brain-bican.org/ontology/mbao/MBA_338 Subfornical organ https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions https://purl.brain-bican.org/ontology/dhbao/DHBA_12104 subfornical organ http://purl.obolibrary.org/obo/UBERON_0002219 subfornical organ https://purl.brain-bican.org/ontology/mbao/MBA_1073 Hemispheric regions https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions https://purl.brain-bican.org/ontology/dhbao/DHBA_10659 cerebellar hemisphere http://purl.obolibrary.org/obo/UBERON_0002245 cerebellar hemisphere https://purl.brain-bican.org/ontology/dhbao/DHBA_10307 olfactory bulb http://purl.obolibrary.org/obo/UBERON_0002264 olfactory bulb https://purl.brain-bican.org/ontology/dhbao/DHBA_12073 olfactory tract http://purl.obolibrary.org/obo/UBERON_0002265 olfactory tract https://purl.brain-bican.org/ontology/mbao/MBA_159 Anterior olfactory nucleus http://purl.obolibrary.org/obo/UBERON_0002266 anterior olfactory nucleus https://purl.brain-bican.org/ontology/dhbao/DHBA_10308 anterior olfactory nucleus http://purl.obolibrary.org/obo/UBERON_0002266 anterior olfactory nucleus https://purl.brain-bican.org/ontology/mbao/MBA_157 Periventricular zone http://purl.obolibrary.org/obo/UBERON_0002271 periventricular zone of hypothalamus https://purl.brain-bican.org/ontology/mbao/MBA_290 Hypothalamic lateral zone http://purl.obolibrary.org/obo/UBERON_0002273 lateral zone of hypothalamus https://purl.brain-bican.org/ontology/mbao/MBA_164 central canal, spinal cord/medulla http://purl.obolibrary.org/obo/UBERON_0002291 central canal of spinal cord https://purl.brain-bican.org/ontology/dhbao/DHBA_146035108 ventricle of spinal cord http://purl.obolibrary.org/obo/UBERON_0002291 central canal of spinal cord https://purl.brain-bican.org/ontology/mbao/MBA_603 fimbria http://purl.obolibrary.org/obo/UBERON_0002310 hippocampus fimbria https://purl.brain-bican.org/ontology/dhbao/DHBA_10575 fimbria http://purl.obolibrary.org/obo/UBERON_0002310 hippocampus fimbria https://purl.brain-bican.org/ontology/dhbao/DHBA_12291 midbrain tectum http://purl.obolibrary.org/obo/UBERON_0002314 midbrain tectum https://purl.brain-bican.org/ontology/dhbao/DHBA_146035048 gray matter of spinal cord http://purl.obolibrary.org/obo/UBERON_0002315 gray matter of spinal cord https://purl.brain-bican.org/ontology/dhbao/DHBA_146035088 white matter of spinal cord http://purl.obolibrary.org/obo/UBERON_0002318 white matter of spinal cord https://purl.brain-bican.org/ontology/mbao/MBA_1089 Hippocampal formation https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions https://purl.brain-bican.org/ontology/dhbao/DHBA_10294 hippocampus (hippocampal formation) http://purl.obolibrary.org/obo/UBERON_0002421 hippocampal formation https://purl.brain-bican.org/ontology/mbao/MBA_145 fourth ventricle http://purl.obolibrary.org/obo/UBERON_0002422 fourth ventricle https://purl.brain-bican.org/ontology/dhbao/DHBA_12805 fourth ventricle http://purl.obolibrary.org/obo/UBERON_0002422 fourth ventricle https://purl.brain-bican.org/ontology/mbao/MBA_477 Striatum http://purl.obolibrary.org/obo/UBERON_0002435 striatum https://purl.brain-bican.org/ontology/dhbao/DHBA_10333 striatum https://purl.brain-bican.org/ontology/dhbao/DHBA_10157 gray matter of forebrain https://purl.brain-bican.org/ontology/mbao/MBA_1022 Globus pallidus, external segment http://purl.obolibrary.org/obo/UBERON_0002476 lateral globus pallidus https://purl.brain-bican.org/ontology/mbao/MBA_1031 Globus pallidus, internal segment http://purl.obolibrary.org/obo/UBERON_0002477 medial globus pallidus https://purl.brain-bican.org/ontology/dhbao/DHBA_10344 internal segment of globus pallidus https://purl.brain-bican.org/ontology/dhbao/DHBA_10157 gray matter of forebrain https://purl.brain-bican.org/ontology/mbao/MBA_170 Dorsal part of the lateral geniculate complex http://purl.obolibrary.org/obo/UBERON_0006331 brainstem nucleus https://purl.brain-bican.org/ontology/dhbao/DHBA_10430 dorsal lateral geniculate nucleus https://purl.brain-bican.org/ontology/dhbao/DHBA_10440 posterior nucleus of thalamus https://purl.brain-bican.org/ontology/dhbao/DHBA_266441551 anterior hypothalamic area http://purl.obolibrary.org/obo/UBERON_0002550 anterior hypothalamic region http://purl.obolibrary.org/obo/UBERON_0035763 cavity of cardiac chamber http://purl.obolibrary.org/obo/UBERON_0002553 anatomical cavity http://purl.obolibrary.org/obo/UBERON_0035809 serous cavity http://purl.obolibrary.org/obo/UBERON_0002553 anatomical cavity https://purl.brain-bican.org/ontology/dhbao/DHBA_12405 basilar part of pons http://purl.obolibrary.org/obo/UBERON_0002567 basal part of pons https://purl.brain-bican.org/ontology/mbao/MBA_709 Ventral posterior complex of the thalamus http://purl.obolibrary.org/obo/UBERON_0006331 brainstem nucleus https://purl.brain-bican.org/ontology/dhbao/DHBA_10423 ventral posterior nucleus of thalamus http://purl.obolibrary.org/obo/UBERON_0002596 ventral posterior nucleus of thalamus https://purl.brain-bican.org/ontology/dhbao/DHBA_12155 limbic lobe http://purl.obolibrary.org/obo/UBERON_0002600 limbic lobe https://purl.brain-bican.org/ontology/mbao/MBA_607 Cochlear nuclei http://purl.obolibrary.org/obo/UBERON_0002610 cochlear nuclear complex https://purl.brain-bican.org/ontology/dhbao/DHBA_12437 cochlear nuclei https://purl.brain-bican.org/ontology/dhbao/DHBA_10654 gray matter of the hindbrain https://purl.brain-bican.org/ontology/mbao/MBA_397 ventral tegmental decussation https://purl.brain-bican.org/ontology/mbao/MBA_1009 fiber tracts https://purl.brain-bican.org/ontology/dhbao/DHBA_12366 ventral tegmental decussation http://purl.obolibrary.org/obo/UBERON_0002615 ventral tegmental decussation https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain https://purl.brain-bican.org/ontology/mbao/MBA_133 Periventricular hypothalamic nucleus, preoptic part http://purl.obolibrary.org/obo/UBERON_0006568 hypothalamic nucleus https://purl.brain-bican.org/ontology/mbao/MBA_452 Median preoptic nucleus http://purl.obolibrary.org/obo/UBERON_0006568 hypothalamic nucleus https://purl.brain-bican.org/ontology/dhbao/DHBA_13063 median preoptic nucleus http://purl.obolibrary.org/obo/UBERON_0006568 hypothalamic nucleus https://purl.brain-bican.org/ontology/dhbao/DHBA_12239 midbrain reticular formation https://purl.brain-bican.org/ontology/dhbao/DHBA_10649 gray matter of midbrain https://purl.brain-bican.org/ontology/dhbao/DHBA_10350 septal nuclei https://purl.brain-bican.org/ontology/dhbao/DHBA_10157 gray matter of forebrain https://purl.brain-bican.org/ontology/mbao/MBA_242 Lateral septal nucleus http://purl.obolibrary.org/obo/UBERON_0002667 lateral septal nucleus https://purl.brain-bican.org/ontology/dhbao/DHBA_10352 lateral septal nucleus http://purl.obolibrary.org/obo/UBERON_0002667 lateral septal nucleus https://purl.brain-bican.org/ontology/mbao/MBA_832 oculomotor nerve https://purl.brain-bican.org/ontology/mbao/MBA_967 cranial nerves https://purl.brain-bican.org/ontology/dhbao/DHBA_12376 root of oculomotor nerve http://purl.obolibrary.org/obo/UBERON_0002668 oculomotor nerve root https://purl.brain-bican.org/ontology/mbao/MBA_763 Vascular organ of the lamina terminalis https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions https://purl.brain-bican.org/ontology/dhbao/DHBA_12106 organum vasculosum laminae terminalis http://purl.obolibrary.org/obo/UBERON_0002689 supraoptic crest https://purl.brain-bican.org/ontology/mbao/MBA_272 Anteroventral periventricular nucleus http://purl.obolibrary.org/obo/UBERON_0006331 brainstem nucleus https://purl.brain-bican.org/ontology/dhbao/DHBA_13061 anteroventral periventricular nucleus http://purl.obolibrary.org/obo/UBERON_0002690 anteroventral periventricular nucleus https://purl.brain-bican.org/ontology/mbao/MBA_749 Ventral tegmental area https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions https://purl.brain-bican.org/ontology/dhbao/DHBA_12261 ventral tegmental area http://purl.obolibrary.org/obo/UBERON_0002691 ventral tegmental area https://purl.brain-bican.org/ontology/mbao/MBA_1008 Geniculate group, dorsal thalamus http://purl.obolibrary.org/obo/UBERON_0006331 brainstem nucleus https://purl.brain-bican.org/ontology/dhbao/DHBA_12776 corticospinal tract http://purl.obolibrary.org/obo/UBERON_0007702 tract of brain https://purl.brain-bican.org/ontology/mbao/MBA_126 Periventricular hypothalamic nucleus, posterior part http://purl.obolibrary.org/obo/UBERON_0006331 brainstem nucleus https://purl.brain-bican.org/ontology/mbao/MBA_1020 Posterior complex of the thalamus http://purl.obolibrary.org/obo/UBERON_0002709 posterior nuclear complex of thalamus https://purl.brain-bican.org/ontology/dhbao/DHBA_10428 posterior nuclear complex of thalamus https://purl.brain-bican.org/ontology/dhbao/DHBA_10157 gray matter of forebrain https://purl.brain-bican.org/ontology/mbao/MBA_863 rubrospinal tract https://purl.brain-bican.org/ontology/mbao/MBA_1009 fiber tracts https://purl.brain-bican.org/ontology/dhbao/DHBA_12782 rubrospinal tract http://purl.obolibrary.org/obo/UBERON_0002714 rubrospinal tract https://purl.brain-bican.org/ontology/mbao/MBA_933 vestibulocochlear nerve https://purl.brain-bican.org/ontology/mbao/MBA_967 cranial nerves https://purl.brain-bican.org/ontology/dhbao/DHBA_12868 root of vestibulocochlear nerve http://purl.obolibrary.org/obo/UBERON_0002731 vestibulocochlear nerve root https://purl.brain-bican.org/ontology/mbao/MBA_138 Lateral group of the dorsal thalamus http://purl.obolibrary.org/obo/UBERON_0006331 brainstem nucleus https://purl.brain-bican.org/ontology/dhbao/DHBA_10349 basal forebrain http://purl.obolibrary.org/obo/UBERON_0002743 basal forebrain https://purl.brain-bican.org/ontology/mbao/MBA_637 Ventral group of the dorsal thalamus http://purl.obolibrary.org/obo/UBERON_0006331 brainstem nucleus https://purl.brain-bican.org/ontology/mbao/MBA_101 Ventral cochlear nucleus http://purl.obolibrary.org/obo/UBERON_0002828 ventral cochlear nucleus https://purl.brain-bican.org/ontology/dhbao/DHBA_12439 ventral cochlear nucleus http://purl.obolibrary.org/obo/UBERON_0002828 ventral cochlear nucleus https://purl.brain-bican.org/ontology/mbao/MBA_96 Dorsal cochlear nucleus http://purl.obolibrary.org/obo/UBERON_0002829 dorsal cochlear nucleus https://purl.brain-bican.org/ontology/dhbao/DHBA_12438 dorsal cochlear nucleus http://purl.obolibrary.org/obo/UBERON_0002829 dorsal cochlear nucleus https://purl.brain-bican.org/ontology/dhbao/DHBA_12440 ventral cochlear nucleus, rostral part http://purl.obolibrary.org/obo/UBERON_0002830 anteroventral cochlear nucleus https://purl.brain-bican.org/ontology/dhbao/DHBA_12441 ventral cochlear nucleus, caudal part http://purl.obolibrary.org/obo/UBERON_0002831 posteroventral cochlear nucleus https://purl.brain-bican.org/ontology/mbao/MBA_773 Hypoglossal nucleus http://purl.obolibrary.org/obo/UBERON_0002871 hypoglossal nucleus https://purl.brain-bican.org/ontology/dhbao/DHBA_12545 hypoglossal nucleus http://purl.obolibrary.org/obo/UBERON_0002871 hypoglossal nucleus https://purl.brain-bican.org/ontology/mbao/MBA_131 Lateral amygdalar nucleus http://purl.obolibrary.org/obo/UBERON_0002886 lateral amygdaloid nucleus https://purl.brain-bican.org/ontology/dhbao/DHBA_10367 lateral nucleus http://purl.obolibrary.org/obo/UBERON_0002886 lateral amygdaloid nucleus https://purl.brain-bican.org/ontology/mbao/MBA_403 Medial amygdalar nucleus http://purl.obolibrary.org/obo/UBERON_0002892 medial amygdaloid nucleus https://purl.brain-bican.org/ontology/mbao/MBA_619 Nucleus of the lateral olfactory tract http://purl.obolibrary.org/obo/UBERON_0002893 nucleus of lateral olfactory tract https://purl.brain-bican.org/ontology/dhbao/DHBA_10309 nucleus of lateral olfactory tract http://purl.obolibrary.org/obo/UBERON_0002893 nucleus of lateral olfactory tract https://purl.brain-bican.org/ontology/mbao/MBA_698 Olfactory areas https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions https://purl.brain-bican.org/ontology/dhbao/DHBA_10614 central sulcus https://purl.brain-bican.org/ontology/dhbao/DHBA_10610 cerebral sulci https://purl.brain-bican.org/ontology/dhbao/DHBA_10622 longitudinal fissure http://purl.obolibrary.org/obo/UBERON_0002921 longitudinal fissure https://purl.brain-bican.org/ontology/mbao/MBA_10704 Dentate gyrus, polymorph layer http://purl.obolibrary.org/obo/UBERON_0002928 dentate gyrus polymorphic layer https://purl.brain-bican.org/ontology/mbao/MBA_733 Ventral posteromedial nucleus of the thalamus http://purl.obolibrary.org/obo/UBERON_0006331 brainstem nucleus https://purl.brain-bican.org/ontology/dhbao/DHBA_10425 ventral posterior medial nucleus http://purl.obolibrary.org/obo/UBERON_0002945 ventral posteromedial nucleus of thalamus https://purl.brain-bican.org/ontology/mbao/MBA_1143 Cerebellar cortex, granular layer http://purl.obolibrary.org/obo/UBERON_0002956 granular layer of cerebellar cortex https://purl.brain-bican.org/ontology/dhbao/DHBA_10293 archicortex https://purl.brain-bican.org/ontology/dhbao/DHBA_10292 allocortex https://purl.brain-bican.org/ontology/mbao/MBA_1144 Cerebellar cortex, molecular layer http://purl.obolibrary.org/obo/UBERON_0002974 molecular layer of cerebellar cortex https://purl.brain-bican.org/ontology/mbao/MBA_1145 Cerebellar cortex, Purkinje layer http://purl.obolibrary.org/obo/UBERON_0002979 Purkinje cell layer of cerebellar cortex https://purl.brain-bican.org/ontology/dhbao/DHBA_12852 flocculonodular lobe http://purl.obolibrary.org/obo/UBERON_0003012 flocculonodular lobe https://purl.brain-bican.org/ontology/dhbao/DHBA_12416 pontine tegmentum http://purl.obolibrary.org/obo/UBERON_0003023 pontine tegmentum https://purl.brain-bican.org/ontology/dhbao/DHBA_10440 posterior nucleus of thalamus http://purl.obolibrary.org/obo/UBERON_0003030 posterior nucleus of thalamus https://purl.brain-bican.org/ontology/dhbao/DHBA_10542 ventricular zone http://purl.obolibrary.org/obo/UBERON_0003053 ventricular zone https://purl.brain-bican.org/ontology/dhbao/DHBA_10153 neural plate http://purl.obolibrary.org/obo/UBERON_0003075 neural plate http://purl.obolibrary.org/obo/UBERON_0036073 respiratory primordium mesenchyme http://purl.obolibrary.org/obo/UBERON_0003104 mesenchyme https://purl.brain-bican.org/ontology/dhbao/DHBA_12320 roof plate of midbrain http://purl.obolibrary.org/obo/UBERON_0003299 roof plate of midbrain https://purl.brain-bican.org/ontology/dhbao/DHBA_12325 floor plate of midbrain http://purl.obolibrary.org/obo/UBERON_0003307 floor plate of midbrain http://purl.obolibrary.org/obo/UBERON_0036343 wall of gallbladder http://purl.obolibrary.org/obo/UBERON_0003697 abdominal wall https://purl.brain-bican.org/ontology/mbao/MBA_463 Field CA3 https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions https://purl.brain-bican.org/ontology/dhbao/DHBA_10299 CA3 region of Hipp http://purl.obolibrary.org/obo/UBERON_0003883 CA3 field of hippocampus https://purl.brain-bican.org/ontology/dhbao/DHBA_10300 CA4 region of Hipp http://purl.obolibrary.org/obo/UBERON_0003884 CA4 field of hippocampus http://purl.obolibrary.org/obo/UBERON_0034969 epithelial layer of duct http://purl.obolibrary.org/obo/UBERON_0003914 epithelial tube http://purl.obolibrary.org/obo/UBERON_0035037 jaw epithelium http://purl.obolibrary.org/obo/UBERON_0003929 digestive tract epithelium https://purl.brain-bican.org/ontology/dhbao/DHBA_12828 cerebellar fissures http://purl.obolibrary.org/obo/UBERON_0003980 cerebellum fissure https://purl.brain-bican.org/ontology/dhbao/DHBA_12698 cerebellar plate http://purl.obolibrary.org/obo/UBERON_0004008 cerebellar plate https://purl.brain-bican.org/ontology/dhbao/DHBA_10549 Ganglionic eminence (VZ in basal nuclei) http://purl.obolibrary.org/obo/UBERON_0004023 ganglionic eminence https://purl.brain-bican.org/ontology/dhbao/DHBA_10550 medial ganglionic eminence http://purl.obolibrary.org/obo/UBERON_0004024 medial ganglionic eminence https://purl.brain-bican.org/ontology/dhbao/DHBA_10551 lateral ganglionic eminence http://purl.obolibrary.org/obo/UBERON_0004025 lateral ganglionic eminence https://purl.brain-bican.org/ontology/dhbao/DHBA_10552 caudal ganglionic eminence http://purl.obolibrary.org/obo/UBERON_0004026 caudal ganglionic eminence https://purl.brain-bican.org/ontology/mbao/MBA_703 Cortical subplate http://purl.obolibrary.org/obo/UBERON_0004035 cortical subplate https://purl.brain-bican.org/ontology/mbao/MBA_91 Interposed nucleus http://purl.obolibrary.org/obo/UBERON_0004073 cerebellum interpositus nucleus https://purl.brain-bican.org/ontology/dhbao/DHBA_12613 interpositus nucleus http://purl.obolibrary.org/obo/UBERON_0004073 cerebellum interpositus nucleus https://purl.brain-bican.org/ontology/mbao/MBA_968 Nodulus (X) https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions http://purl.obolibrary.org/obo/UBERON_0036072 respiratory primordium epithelium http://purl.obolibrary.org/obo/UBERON_0015833 foregut epithelium https://purl.brain-bican.org/ontology/mbao/MBA_236 Main olfactory bulb, mitral layer http://purl.obolibrary.org/obo/UBERON_0004186 olfactory bulb mitral cell layer https://purl.brain-bican.org/ontology/dhbao/DHBA_11329 mitral cell layer of olfactory bulb http://purl.obolibrary.org/obo/UBERON_0004186 olfactory bulb mitral cell layer https://purl.brain-bican.org/ontology/mbao/MBA_579 external capsule http://purl.obolibrary.org/obo/UBERON_0004545 external capsule of telencephalon https://purl.brain-bican.org/ontology/dhbao/DHBA_10573 external capsule https://purl.brain-bican.org/ontology/dhbao/DHBA_10557 white matter of forebrain https://purl.brain-bican.org/ontology/mbao/MBA_901 trigeminal nerve https://purl.brain-bican.org/ontology/mbao/MBA_967 cranial nerves https://purl.brain-bican.org/ontology/dhbao/DHBA_12865 root of trigeminal nerve http://purl.obolibrary.org/obo/UBERON_0004673 trigeminal nerve root https://purl.brain-bican.org/ontology/mbao/MBA_798 facial nerve https://purl.brain-bican.org/ontology/mbao/MBA_967 cranial nerves https://purl.brain-bican.org/ontology/dhbao/DHBA_12862 root of facial nerve http://purl.obolibrary.org/obo/UBERON_0004674 facial nerve root https://purl.brain-bican.org/ontology/mbao/MBA_813 hypoglossal nerve https://purl.brain-bican.org/ontology/mbao/MBA_967 cranial nerves https://purl.brain-bican.org/ontology/dhbao/DHBA_12886 root of hypoglossal nerve http://purl.obolibrary.org/obo/UBERON_0004675 hypoglossal nerve root https://purl.brain-bican.org/ontology/mbao/MBA_10703 Dentate gyrus, molecular layer http://purl.obolibrary.org/obo/UBERON_0004679 dentate gyrus molecular layer https://purl.brain-bican.org/ontology/dhbao/DHBA_10391 dorsal thalamus http://purl.obolibrary.org/obo/UBERON_0004703 dorsal thalamus https://purl.brain-bican.org/ontology/dhbao/DHBA_10311 piriform cortex http://purl.obolibrary.org/obo/UBERON_0004725 piriform cortex https://purl.brain-bican.org/ontology/dhbao/DHBA_10662 myelencephalon (medulla oblongata) http://purl.obolibrary.org/obo/UBERON_0005290 myelencephalon https://purl.brain-bican.org/ontology/mbao/MBA_695 Cortical plate http://purl.obolibrary.org/obo/UBERON_0005343 cortical plate https://purl.brain-bican.org/ontology/dhbao/DHBA_10515 cortical plate http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure https://purl.brain-bican.org/ontology/mbao/MBA_1041 Paraflocculus https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions https://purl.brain-bican.org/ontology/dhbao/DHBA_11327 glomerular layer of olfactory bulb http://purl.obolibrary.org/obo/UBERON_0005377 olfactory bulb glomerular layer https://purl.brain-bican.org/ontology/mbao/MBA_220 Main olfactory bulb, granule layer http://purl.obolibrary.org/obo/UBERON_0005378 olfactory bulb granule cell layer https://purl.brain-bican.org/ontology/mbao/MBA_632 Dentate gyrus, granule cell layer http://purl.obolibrary.org/obo/UBERON_0005381 dentate gyrus granule cell layer https://purl.brain-bican.org/ontology/mbao/MBA_485 Striatum dorsal region http://purl.obolibrary.org/obo/UBERON_0005382 dorsal striatum https://purl.brain-bican.org/ontology/mbao/MBA_672 Caudoputamen http://purl.obolibrary.org/obo/UBERON_0005383 caudate-putamen https://purl.brain-bican.org/ontology/mbao/MBA_107 Somatomotor areas, Layer 1 http://purl.obolibrary.org/obo/UBERON_0005390 cortical layer I https://purl.brain-bican.org/ontology/mbao/MBA_644 Somatomotor areas, Layer 6a http://purl.obolibrary.org/obo/UBERON_0005395 cortical layer VI https://purl.brain-bican.org/ontology/mbao/MBA_493 Striatum ventral region http://purl.obolibrary.org/obo/UBERON_0005403 ventral striatum https://purl.brain-bican.org/ontology/dhbao/DHBA_12667 rhombomere 1 https://purl.brain-bican.org/ontology/dhbao/DHBA_12664 hindbrain neuromeres https://purl.brain-bican.org/ontology/mbao/MBA_744 cerebellar commissure https://purl.brain-bican.org/ontology/mbao/MBA_1009 fiber tracts https://purl.brain-bican.org/ontology/mbao/MBA_1016 olfactory nerve layer of main olfactory bulb http://purl.obolibrary.org/obo/UBERON_0005978 olfactory bulb outer nerve layer https://purl.brain-bican.org/ontology/dhbao/DHBA_11326 olfactory nerve layer of olfactory bulb http://purl.obolibrary.org/obo/UBERON_0005978 olfactory bulb outer nerve layer https://purl.brain-bican.org/ontology/dhbao/DHBA_10366 basolateral nuclear group https://purl.brain-bican.org/ontology/dhbao/DHBA_10157 gray matter of forebrain https://purl.brain-bican.org/ontology/dhbao/DHBA_10372 corticomedial nuclear group https://purl.brain-bican.org/ontology/dhbao/DHBA_10157 gray matter of forebrain https://purl.brain-bican.org/ontology/dhbao/DHBA_10664 rhombic lip http://purl.obolibrary.org/obo/UBERON_0006215 rhombic lip https://purl.brain-bican.org/ontology/dhbao/DHBA_10595 ventricles of forebrain http://purl.obolibrary.org/obo/UBERON_0006284 early prosencephalic vesicle https://purl.brain-bican.org/ontology/mbao/MBA_118 Periventricular hypothalamic nucleus, intermediate part http://purl.obolibrary.org/obo/UBERON_8440008 periventricular hypothalamic nucleus, intermediate part https://purl.brain-bican.org/ontology/mbao/MBA_803 Pallidum http://purl.obolibrary.org/obo/UBERON_0011300 gray matter of telencephalon https://purl.brain-bican.org/ontology/mbao/MBA_818 Pallidum, dorsal region https://purl.brain-bican.org/ontology/mbao/MBA_803 Pallidum https://purl.brain-bican.org/ontology/mbao/MBA_967 cranial nerves https://purl.brain-bican.org/ontology/mbao/MBA_1009 fiber tracts https://purl.brain-bican.org/ontology/dhbao/DHBA_12888 root of vagus nerve http://purl.obolibrary.org/obo/UBERON_0011213 root of vagus nerve https://purl.brain-bican.org/ontology/mbao/MBA_128 Midbrain reticular nucleus http://purl.obolibrary.org/obo/UBERON_0007415 nucleus of midbrain reticular formation https://purl.brain-bican.org/ontology/mbao/MBA_752 cerebellar peduncles http://purl.obolibrary.org/obo/UBERON_0007416 cerebellar peduncle https://purl.brain-bican.org/ontology/mbao/MBA_275 Lateral septal complex http://purl.obolibrary.org/obo/UBERON_0007628 lateral septal complex https://purl.brain-bican.org/ontology/mbao/MBA_466 alveus http://purl.obolibrary.org/obo/UBERON_0014532 white matter lamina of cerebral hemisphere https://purl.brain-bican.org/ontology/dhbao/DHBA_10570 alveus http://purl.obolibrary.org/obo/UBERON_0014532 white matter lamina of cerebral hemisphere https://purl.brain-bican.org/ontology/dhbao/DHBA_266441713 trigeminal nuclei https://purl.brain-bican.org/ontology/dhbao/DHBA_10654 gray matter of the hindbrain https://purl.brain-bican.org/ontology/mbao/MBA_997 brain http://purl.obolibrary.org/obo/UBERON_0008823 neural tube derived brain https://purl.brain-bican.org/ontology/dhbao/DHBA_10155 brain http://purl.obolibrary.org/obo/UBERON_0008823 neural tube derived brain https://purl.brain-bican.org/ontology/dhbao/DHBA_146035120 roots of spinal nerves http://purl.obolibrary.org/obo/UBERON_0011215 central nervous system cell part cluster https://purl.brain-bican.org/ontology/dhbao/DHBA_12182 pretectal nuclear complex http://purl.obolibrary.org/obo/UBERON_0014450 pretectal nucleus https://purl.brain-bican.org/ontology/dhbao/DHBA_10665 upper (rostral) rhombic lip http://purl.obolibrary.org/obo/UBERON_0009841 upper rhombic lip http://purl.obolibrary.org/obo/UBERON_0036375 wall of right ureter http://purl.obolibrary.org/obo/UBERON_0009916 wall of ureter http://purl.obolibrary.org/obo/UBERON_0036376 wall of left ureter http://purl.obolibrary.org/obo/UBERON_0009916 wall of ureter https://purl.brain-bican.org/ontology/dhbao/DHBA_12531 retrotrapezoid nucleus http://purl.obolibrary.org/obo/UBERON_0009918 retrotrapezoid nucleus https://purl.brain-bican.org/ontology/mbao/MBA_507 Main olfactory bulb https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions https://purl.brain-bican.org/ontology/dhbao/DHBA_12322 basal plate of midbrain https://purl.brain-bican.org/ontology/dhbao/DHBA_10649 gray matter of midbrain http://purl.obolibrary.org/obo/UBERON_0035555 lateral line sense organ http://purl.obolibrary.org/obo/UBERON_0010521 electroreceptor organ http://purl.obolibrary.org/obo/UBERON_0035128 manus cartilage element http://purl.obolibrary.org/obo/UBERON_0015064 autopod cartilage http://purl.obolibrary.org/obo/UBERON_0035129 pes cartilage element http://purl.obolibrary.org/obo/UBERON_0015064 autopod cartilage https://purl.brain-bican.org/ontology/mbao/MBA_246 Midbrain reticular nucleus, retrorubral area https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions https://purl.brain-bican.org/ontology/dhbao/DHBA_12289 retrorubral field http://purl.obolibrary.org/obo/UBERON_0011172 retrorubral area of midbrain reticular nucleus https://purl.brain-bican.org/ontology/mbao/MBA_917 vagus nerve https://purl.brain-bican.org/ontology/mbao/MBA_967 cranial nerves https://purl.brain-bican.org/ontology/dhbao/DHBA_12883 root of accessory nerve http://purl.obolibrary.org/obo/UBERON_0014615 accessory nerve root https://purl.brain-bican.org/ontology/dhbao/DHBA_10610 cerebral sulci http://purl.obolibrary.org/obo/UBERON_0013118 sulcus of brain https://purl.brain-bican.org/ontology/dhbao/DHBA_10431 magnocellular layer of DLG http://purl.obolibrary.org/obo/UBERON_0013606 magnocellular layer of dorsal nucleus of lateral geniculate body https://purl.brain-bican.org/ontology/mbao/MBA_495 Field CA3, pyramidal layer http://purl.obolibrary.org/obo/UBERON_0014550 pyramidal layer of CA3 https://purl.brain-bican.org/ontology/mbao/MBA_486 Field CA3, stratum oriens http://purl.obolibrary.org/obo/UBERON_0014553 CA3 stratum oriens https://purl.brain-bican.org/ontology/mbao/MBA_504 Field CA3, stratum radiatum http://purl.obolibrary.org/obo/UBERON_0014556 CA3 stratum radiatum https://purl.brain-bican.org/ontology/mbao/MBA_717 accessory spinal nerve https://purl.brain-bican.org/ontology/mbao/MBA_1009 fiber tracts http://purl.obolibrary.org/obo/UBERON_0035053 interlobular duct of salivary gland http://purl.obolibrary.org/obo/UBERON_0035049 excretory duct of salivary gland https://purl.brain-bican.org/ontology/dhbao/DHBA_10292 allocortex http://purl.obolibrary.org/obo/UBERON_0014734 allocortex https://purl.brain-bican.org/ontology/dhbao/DHBA_10306 paleocortex (semicortex) https://purl.brain-bican.org/ontology/dhbao/DHBA_10292 allocortex https://purl.brain-bican.org/ontology/mbao/MBA_1108 genu of corpus callosum https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions https://purl.brain-bican.org/ontology/dhbao/DHBA_10563 genu of corpus callosum http://purl.obolibrary.org/obo/UBERON_0015599 genu of corpus callosum https://purl.brain-bican.org/ontology/dhbao/DHBA_10208 parietal neocortex https://purl.brain-bican.org/ontology/dhbao/DHBA_10157 gray matter of forebrain https://purl.brain-bican.org/ontology/dhbao/DHBA_10235 temporal neocortex https://purl.brain-bican.org/ontology/dhbao/DHBA_10157 gray matter of forebrain https://purl.brain-bican.org/ontology/dhbao/DHBA_10650 white matter of midbrain http://purl.obolibrary.org/obo/UBERON_0016554 white matter of midbrain https://purl.brain-bican.org/ontology/mbao/MBA_993 Secondary motor area https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions https://purl.brain-bican.org/ontology/dhbao/DHBA_10168 premotor cortex (area 6) http://purl.obolibrary.org/obo/UBERON_0016634 premotor cortex https://purl.brain-bican.org/ontology/dhbao/DHBA_10668 white matter of hindbrain http://purl.obolibrary.org/obo/UBERON_0019258 white matter of hindbrain https://purl.brain-bican.org/ontology/dhbao/DHBA_10557 white matter of forebrain http://purl.obolibrary.org/obo/UBERON_0019261 white matter of forebrain https://purl.brain-bican.org/ontology/dhbao/DHBA_10654 gray matter of the hindbrain http://purl.obolibrary.org/obo/UBERON_0019263 gray matter of hindbrain https://purl.brain-bican.org/ontology/dhbao/DHBA_10157 gray matter of forebrain http://purl.obolibrary.org/obo/UBERON_0019264 gray matter of forebrain https://purl.brain-bican.org/ontology/dhbao/DHBA_10649 gray matter of midbrain http://purl.obolibrary.org/obo/UBERON_0019267 gray matter of midbrain https://purl.brain-bican.org/ontology/mbao/MBA_808 glossopharyngeal nerve https://purl.brain-bican.org/ontology/mbao/MBA_967 cranial nerves https://purl.brain-bican.org/ontology/dhbao/DHBA_12887 root of glossopharyngeal nerve http://purl.obolibrary.org/obo/UBERON_0019310 glossopharyngeal nerve root https://purl.brain-bican.org/ontology/mbao/MBA_840 olfactory nerve https://purl.brain-bican.org/ontology/mbao/MBA_967 cranial nerves https://purl.brain-bican.org/ontology/mbao/MBA_822 Retrohippocampal region https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions https://purl.brain-bican.org/ontology/mbao/MBA_365 thalamic peduncles http://purl.obolibrary.org/obo/UBERON_0022236 peduncle of thalamus https://purl.brain-bican.org/ontology/dhbao/DHBA_10568 forebrain ipsilateral fiber tracts http://purl.obolibrary.org/obo/UBERON_0022247 forebrain ipsilateral fiber tracts https://purl.brain-bican.org/ontology/dhbao/DHBA_10593 thalamic fasciculus http://purl.obolibrary.org/obo/UBERON_0022254 ventral thalamic fasciculus https://purl.brain-bican.org/ontology/mbao/MBA_212 Main olfactory bulb, glomerular layer http://purl.obolibrary.org/obo/UBERON_0023934 olfactory bulb main glomerular layer https://purl.brain-bican.org/ontology/dhbao/DHBA_12024 forceps minor (frontalis) https://purl.brain-bican.org/ontology/dhbao/DHBA_10557 white matter of forebrain https://purl.brain-bican.org/ontology/dhbao/DHBA_12695 marginal zone of cerebellum https://purl.brain-bican.org/ontology/dhbao/DHBA_12694 marginal zone of hindbrain https://purl.brain-bican.org/ontology/dhbao/DHBA_12694 marginal zone of hindbrain http://purl.obolibrary.org/obo/UBERON_0034709 hindbrain marginal layer http://purl.obolibrary.org/obo/CLM_5022162 Cdh1,Acvr1c,Adamts15,Pax2 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022203 Slc25a34,C4b (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022214 Glp1r 9 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5007972 Gm45459, Afap1l2 (NSforest). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5007040 Apod,Aqp1,Cldn5 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5016800 Slco1c1,Gria2,Shisa9 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5007039 Cldn5,Adamts12 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5007994 Tmem119, Cx3cr1 (NSforest). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5000360 Gja1,Hs3st3a1 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5001606 Thbd,Ccn3 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022185 Sez6l,Unc13c (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022261 A330076C08Rik (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5016835 Pf4 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5001601 Gpr17,Bmp4 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5000358 Aqp4,Cd38,Agt,Itih3 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5007722 Adora2a, Ppp1r1b (NSforest). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5016802 Zfp536,Hopx (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5006969 Gfap,Ddn,Myoc,Rasl10b (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022265 Cubn 4 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022263 Pde11a 3 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5001602 9630013A20Rik,Ptprb (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_1001239 NS forest marker set of diffuse bipolar 4a cell (Human retina). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_1001240 NS forest marker set of OFFx cell (Human retina). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_1001241 NS forest marker set of cone retinal bipolar cell (Human retina). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_1001242 NS forest marker set of diffuse bipolar 3b cell (Human retina). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_1001243 NS forest marker set of diffuse bipolar 1 cell (Human retina). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_1001244 NS forest marker set of diffuse bipolar 6 cell (Human retina). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_1001245 NS forest marker set of diffuse bipolar 2 cell (Human retina). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_1001246 NS forest marker set of diffuse bipolar 4a cell (Human retina). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_1001247 NS forest marker set of flat midget bipolar cell (Human retina). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_1001248 NS forest marker set of giant bipolar cell (Human retina). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_1001249 NS forest marker set of diffuse bipolar 3a cell (Human retina). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_1001250 NS forest marker set of ON-blue cone bipolar cell (Human retina). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_1001251 NS forest marker set of rod bipolar cell (Human retina). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_1001252 NS forest marker set of invaginating midget bipolar cell (Human retina). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_1001253 NS forest marker set of diffuse bipolar 3b cell (Human retina). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_1001254 NS forest marker set of diffuse bipolar 1 cell (Human retina). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_1001255 NS forest marker set of OFFx cell (Human retina). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_1001256 NS forest marker set of diffuse bipolar 4b cell (Human retina). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_1001257 NS forest marker set of diffuse bipolar 6 cell (Human retina). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_1001258 NS forest marker set of diffuse bipolar 2 cell (Human retina). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_1001259 NS forest marker set of ON-blue cone bipolar cell (Human retina). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_1001260 NS forest marker set of diffuse bipolar 3a cell (Human retina). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_1001261 NS forest marker set of cone retinal bipolar cell (Human retina). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_1001262 NS forest marker set of flat midget bipolar cell (Human retina). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_1001263 NS forest marker set of diffuse bipolar 4a cell (Human retina). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_1001264 NS forest marker set of invaginating midget bipolar cell (Human retina). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_1001265 NS forest marker set of giant bipolar cell (Human retina). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_1001266 NS forest marker set of rod bipolar cell (Human retina). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5006993 Cnmd,Sfta3-ps (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5007036 Apod,Klk6,Dlc1 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5006356 Cngb3,Ush2a (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5016792 Plcxd2,Fgf10 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5016799 C4b,Prelp (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022237 Neil3,Irx2 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5016785 P3h2,Lrrc38 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5007020 Pdgfra,Olig1,Rmi2,Col27a1 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5006978 S1pr1,Thbs4,Gm29683,Slc39a12 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022178 Galnt15 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5007029 9630013A20Rik,Dbx2,Rassf10 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022257 Il33,Gm5087 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5000101 Prkch,Slc32a1,Drd1 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5000348 Tmem204,Slc6a5 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5000351 Homer3,Tfap2b,Sorcs3,Cacna1e (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5000353 Pcp2 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5000366 Pdgfra (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5001564 Hmga2,Afap1l2 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5001565 Pthlh,Tfap2b,Rspo2 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5001566 Pax2,C1ql3,Tfap2b,Gabrb1 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5001569 Dnah11,Sla,Gldc,Sdk2 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5001574 Gabra6,Lmx1a (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5001579 Gfap,Lhfpl3,Gria1,Hopx (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5001580 Gja1,A330076C08Rik,Itih3,Gria2 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5001581 Myoc,Camk2a (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5001582 Hepacam,E330013P04Rik (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5001583 Gja1,Grin2c,Dcc,Slc7a10 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5001588 Ednrb,Hs3st3a1,C230072F16Rik,Gria2 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5001593 Gpr50,Ccdc170,Nkx2-4 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5001615 Mrc1,Maf (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5004314 Gnrh1 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5006922 Il22,Edaradd (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5006956 Gpr37l1,Ctxn3 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5006957 Dao,Efemp1 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5006959 Gfap,Slc36a2,Sfrp5 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5006960 Gfap,Sfrp5,Cldn10,Riiad1 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5006961 Myoc,Six3os1,Slc36a2 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5006964 Gja1,A330076C08Rik,Sfrp5,Gria2 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5006970 Myoc,Dio2,Lncpint (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5006971 Myoc,Sptbn2,Alpk1 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5006972 Gm6145,E330013P04Rik,Slc39a12 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5006973 Mcm6,Egfr,Pcsk6 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5006974 Gja1,Cxcl5,Ddn (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5006985 C230072F16Rik,Dipk1c,Ecrg4 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5006994 C230072F16Rik,Glp1r (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5006995 Dynlrb2,Mylk3,Sfta3-ps (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5006996 Ccdc170,Nkx2-4,Dock8 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5006997 Pdzph1,Wdr63,Dscaml1,P3h2 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5006998 Ccdc146,Tbx3,Otx2 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5006999 Gpr50,Frzb,Foxd2os (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5007013 Sspo,Wfdc2 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5007014 2900040C04Rik,Tbc1d1 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5007015 2900040C04Rik,Slc17a8 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5007016 Pdgfra,Pclaf,Mki67,Foxg1 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5007017 Pdgfra,Pclaf,Irx2 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5007018 Pdgfra,Olig1,Mms22l,Top2a (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5007019 Pdgfra,Olig1,Col27a1 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5007022 Gpr17,Bmp4,Zfp36l1 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5007023 Gpr17,Gp1bb,Pdzd2,Plekhg1 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5007025 9630013A20Rik,Bmp4,Mob3b (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5007026 9630013A20Rik,Rab32,Opalin (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5007028 9630013A20Rik,Grin2b (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5007030 9630013A20Rik,Rgs16,Rhbdl2 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5007032 Opalin,Cxcl12,Efhd1 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5007033 9630013A20Rik,Ppp1r14a,Mroh3 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5007034 Prr5l,Hapln2,Enpp6,Grm7 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5007037 Opalin,Grm3,Gm5087 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5007038 Mog,Anln,Gm32633 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5007045 Prg4,Cubn (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5007062 C1qa,Tmem119 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5007063 Mrc1,Pf4 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5007064 Mrc1,Pf4,Fos (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5007635 Gnrh1 (NSforest). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5007645 Gnb3, Pde6g, Gm44196 (NSforest). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5007648 Tfap2a, Pvalb (NSforest). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5007649 Gabra6 (NSforest). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5007651 Olig1, Pllp (NSforest). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5007721 Pdyn, Rarb (NSforest). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5007802 Gnrh1 2 (NSforest). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5007922 Pde6g, Gnb3, Gm44196 (NSforest). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5007968 Fam107b, Pvalb, Bhlhe22 (NSforest). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5007970 Scrg1, Grm2 (NSforest). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5007971 Gldc, Pvalb (NSforest). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5007973 Pcp2, Arhgef33 (NSforest). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5007974 Gabra6, Cbln3 (NSforest). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5007976 Gdf10, Dao (NSforest). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5007977 Hsd11b1, Cyp26b1, Mlc1 (NSforest). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5007980 Islr, Gldc (NSforest). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5007982 Gpr50, S100a6 (NSforest). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5007983 Ccdc153, Tmem212 (NSforest). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5007984 Spp2, Mlc1 (NSforest). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5007986 Gpr17, Pdgfra (NSforest). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5007987 Fa2h, Cldn11 (NSforest). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5007989 Prg4 (NSforest). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5007995 F13a1, Pf4 (NSforest). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5016781 Rftn1,Iltifb (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5016786 Gm20754 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5016788 Zfp385c,Tfap2b (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5016789 Pax2,Spns2 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5016793 Pcdh7,Grin2a,St6gal1 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5016801 Myoc (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5016803 Brinp3,Hsd11b1,Grin2c (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5016805 Sfrp1,Meis2,Retreg1 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5016806 Greb1 4 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5016808 C230072F16Rik (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5016812 Lpl 4 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5016813 Grid1,Nkx2-4 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5016818 Ttr (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5016821 Bmp4 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5016823 Cxcl12,2210011C24Rik (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5016824 Efhd1,Spock3 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5019534 Gnrh1 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022155 Ly6d (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022177 Dao,Efemp1 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022180 Nuf2,Shroom3 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022181 Six3os1 2 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022182 Kcnk10,C4b (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022183 Mecom,Prelp (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022186 Fam227b,Shroom3 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022187 Gm30524 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022188 Myoc,Kcne1l,Alpk1 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022190 Myoc,Lncpint (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022191 Myoc,Jph4,Alpk1 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022193 Mcm6 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022194 Cxcl5,Kif5a (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022195 Fam163a,Nr2f1,Kcnq1ot1 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022196 Zic4 2 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022197 Crym,Gabbr2 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022198 Gm29683 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022199 Hs3st3a1,Sfrp1 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022200 Adamts18 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022201 Greb1,Il33 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022202 Stk32a 3 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022205 Ecrg4 2 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022206 Sfrp1,Aqp4 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022215 Mylk3 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022216 Mroh5 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022217 Dscaml1,P3h2 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022220 Ecrg4 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022233 Sspo,Wfdc2 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022234 Tbc1d1 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022236 Neil3,Foxg1 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022238 Mms22l,Foxg1,Top2a (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022240 Rmi2,Col27a1 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022242 Rgcc,Plpp4 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022243 Rgcc,9130019P16Rik (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022245 Bmp4,Mob3b (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022246 Vwc2,Opalin (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022247 Bmp4,Cck,Ptger1 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022249 Dbx2,Rassf10 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022250 Rgs16,Rhbdl2 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022251 Il23a,Opalin,Ptprb (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022252 Cxcl12,Efhd1 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022253 Il23a,Ppp1r14a (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022255 Spock3,Rhoj (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022258 Sspo,Selenop (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022259 Adamts12 4 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022260 Gdpd4,Cldn5 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022262 Rasgef1c (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022264 Dapl1 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022283 Mrc1,Pf4 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022284 Fos (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5024421 Gpr17, Bmp4, Neu4, Fyn (CAS evidence). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5024422 Tcf7l2, Klk6, Cemip2, Casr (CAS evidence). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5024424 Klk6 (CAS evidence). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5029176 Crx, Gngt1, Tph1, Asmt, Gngt2 (CAS evidence). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5029833 Sspo (CAS evidence). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022235 Slc17a8 7 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5001603 Cldn11,Sec14l5,9630013A20Rik (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5000359 Gja1,Lhx2,Gpc5,Nr2f1 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5007043 Slc47a1,Pde11a (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022192 Clstn2 2 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5007985 2900040C04Rik (NSforest). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5006983 Aqp4,Hs3st3a1,Slc25a34,C4b (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5001598 2900040C04Rik (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022176 Gpr37l1,Ctxn3 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5000362 Gpr50,Apoe (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022256 Art3 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5006984 S1pr1,Chrdl1,Sfrp1,Atp13a4 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5007969 Inhba, Tfap2b (NSforest). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5006986 S1pr1,6530411M01Rik,Sfrp1,Aqp4 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5007979 Mfge8, Htra1, Fam107a (NSforest). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5000349 Bmp6,Slc6a5,Zic1,Shisa9,Rgs6 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5001576 Sln,Lmx1a (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022239 Col27a1 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5016825 Aqp1,Foxd3 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5021576 Cngb3,Ush2a (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5000370 Apod,Slc6a13 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5006982 Aqp4,Prss23,Stk32a (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022241 Cenpa (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5006966 Slc7a10,Cyp26b1,Igfbp2,Shroom3 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5001592 Cnmd,Lpl (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5001585 Gja1,Thbs4,Kcnk10,Pak1 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5006958 Gfap,Galnt15,Agt (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5006963 Dao,Mecom,Fbln5,Prelp (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5022184 Fzd2,Gria2,Ttll3 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5000102 Adora2a,Phactr1,Pcp4l1 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5006979 S1pr1,Thbs4,Hs3st3a1,Sfrp1 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5006935 Ly6d,Kit (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5007027 9630013A20Rik,Bmp4,Cck,Ptger1 (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5006962 Agt,Prss35,C4b (Yao). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5016794 Cntn3 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5007978 Agt, Aldh1a1, Mlc1 (NSforest). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_5016783 Cdh22 (Yao - within subclass). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/NCBITaxon_9481 Callithrix http://purl.obolibrary.org/obo/NCBITaxon_9480 Callitrichinae http://purl.obolibrary.org/obo/UBERON_0036303 vasculature of central nervous system http://purl.obolibrary.org/obo/UBERON_0036302 vasculature of central nervous system plus retina http://purl.obolibrary.org/obo/NCBITaxon_34346 Schizosaccharomycetales http://purl.obolibrary.org/obo/NCBITaxon_147554 Schizosaccharomycetes http://purl.obolibrary.org/obo/NCBITaxon_9986 Oryctolagus cuniculus http://purl.obolibrary.org/obo/NCBITaxon_9984 Oryctolagus http://purl.obolibrary.org/obo/UBERON_0037447 wall of male urethra http://purl.obolibrary.org/obo/UBERON_0036521 wall of urethra http://purl.obolibrary.org/obo/UBERON_0037455 wall of female urethra http://purl.obolibrary.org/obo/UBERON_0036521 wall of urethra http://purl.obolibrary.org/obo/UBERON_0036654 wall of lateral ventricle http://purl.obolibrary.org/obo/UBERON_0036661 wall of ventricular system of brain http://purl.obolibrary.org/obo/UBERON_0036656 wall of third ventricle http://purl.obolibrary.org/obo/UBERON_0036661 wall of ventricular system of brain http://purl.obolibrary.org/obo/UBERON_0036657 wall of fourth ventricle http://purl.obolibrary.org/obo/UBERON_0036661 wall of ventricular system of brain https://purl.brain-bican.org/ontology/mbao/MBA_623 Cerebral nuclei http://purl.obolibrary.org/obo/UBERON_8440012 cerebral nuclei https://purl.brain-bican.org/ontology/dhbao/DHBA_10331 cerebral nuclei http://purl.obolibrary.org/obo/UBERON_8440012 cerebral nuclei https://purl.brain-bican.org/ontology/mbao/MBA_278 Striatum-like amygdalar nuclei http://purl.obolibrary.org/obo/UBERON_8440030 striatum-like amygdalar nuclei http://purl.obolibrary.org/obo/NCBITaxon_9605 Homo http://purl.obolibrary.org/obo/NCBITaxon_207598 Homininae http://purl.obolibrary.org/obo/NCBITaxon_9479 Platyrrhini http://purl.obolibrary.org/obo/NCBITaxon_314293 Simiiformes http://purl.obolibrary.org/obo/NCBITaxon_9526 Catarrhini http://purl.obolibrary.org/obo/NCBITaxon_314293 Simiiformes http://purl.obolibrary.org/obo/NCBITaxon_9604 Hominidae http://purl.obolibrary.org/obo/NCBITaxon_314295 Hominoidea http://purl.obolibrary.org/obo/NCBITaxon_379583 Feliformia http://purl.obolibrary.org/obo/NCBITaxon_33554 Carnivora http://purl.obolibrary.org/obo/NCBITaxon_314293 Simiiformes http://purl.obolibrary.org/obo/NCBITaxon_376913 Haplorrhini http://purl.obolibrary.org/obo/NCBITaxon_9681 Felidae http://purl.obolibrary.org/obo/NCBITaxon_379583 Feliformia http://purl.obolibrary.org/obo/NCBITaxon_6243 Rhabditidae http://purl.obolibrary.org/obo/NCBITaxon_55879 Rhabditoidea http://purl.obolibrary.org/obo/NCBITaxon_6237 Caenorhabditis http://purl.obolibrary.org/obo/NCBITaxon_55885 Peloderinae http://purl.obolibrary.org/obo/NCBITaxon_55885 Peloderinae http://purl.obolibrary.org/obo/NCBITaxon_6243 Rhabditidae http://purl.obolibrary.org/obo/NCBITaxon_376913 Haplorrhini http://purl.obolibrary.org/obo/NCBITaxon_9443 Primates http://purl.obolibrary.org/obo/NCBITaxon_9498 Cebidae http://purl.obolibrary.org/obo/NCBITaxon_9479 Platyrrhini http://purl.obolibrary.org/obo/NCBITaxon_314295 Hominoidea http://purl.obolibrary.org/obo/NCBITaxon_9526 Catarrhini http://purl.obolibrary.org/obo/NCBITaxon_207598 Homininae http://purl.obolibrary.org/obo/NCBITaxon_9604 Hominidae http://purl.obolibrary.org/obo/NCBITaxon_9788 Equidae http://purl.obolibrary.org/obo/NCBITaxon_9787 Perissodactyla http://purl.obolibrary.org/obo/NCBITaxon_9789 Equus http://purl.obolibrary.org/obo/NCBITaxon_9788 Equidae http://purl.obolibrary.org/obo/NCBITaxon_9979 Leporidae http://purl.obolibrary.org/obo/NCBITaxon_9975 Lagomorpha http://purl.obolibrary.org/obo/UBERON_0035606 cartilage of external acoustic meatus http://purl.obolibrary.org/obo/UBERON_0034944 zone of organ http://purl.obolibrary.org/obo/UBERON_0034996 outer renal medulla loop of Henle http://purl.obolibrary.org/obo/UBERON_0034997 renal medulla loop of Henle http://purl.obolibrary.org/obo/NCBITaxon_9483 Callithrix jacchus http://purl.obolibrary.org/obo/NCBITaxon_1965096 Callithrix https://purl.brain-bican.org/ontology/mbao/MBA_219 Somatomotor areas, Layer 2/3 http://purl.obolibrary.org/obo/UBERON_8440000 cortical layer II/III https://purl.brain-bican.org/ontology/mbao/MBA_947 Somatomotor areas, Layer 6b http://purl.obolibrary.org/obo/UBERON_8440003 cortical layer VIb https://purl.brain-bican.org/ontology/mbao/MBA_10687 Paraflocculus, granular layer https://purl.brain-bican.org/ontology/mbao/MBA_1143 Cerebellar cortex, granular layer https://purl.brain-bican.org/ontology/mbao/MBA_10690 Flocculus, granular layer https://purl.brain-bican.org/ontology/mbao/MBA_1143 Cerebellar cortex, granular layer https://purl.brain-bican.org/ontology/mbao/MBA_10735 Nodulus (X), granular layer https://purl.brain-bican.org/ontology/mbao/MBA_1143 Cerebellar cortex, granular layer https://purl.brain-bican.org/ontology/mbao/MBA_10689 Paraflocculus, molecular layer https://purl.brain-bican.org/ontology/mbao/MBA_1144 Cerebellar cortex, molecular layer https://purl.brain-bican.org/ontology/mbao/MBA_10737 Nodulus (X), molecular layer https://purl.brain-bican.org/ontology/mbao/MBA_1144 Cerebellar cortex, molecular layer https://purl.brain-bican.org/ontology/mbao/MBA_10692 Flocculus, molecular layer https://purl.brain-bican.org/ontology/mbao/MBA_1144 Cerebellar cortex, molecular layer https://purl.brain-bican.org/ontology/mbao/MBA_10688 Paraflocculus, Purkinje layer https://purl.brain-bican.org/ontology/mbao/MBA_1145 Cerebellar cortex, Purkinje layer https://purl.brain-bican.org/ontology/mbao/MBA_10691 Flocculus, Purkinje layer https://purl.brain-bican.org/ontology/mbao/MBA_1145 Cerebellar cortex, Purkinje layer https://purl.brain-bican.org/ontology/mbao/MBA_10736 Nodulus (X), Purkinje layer https://purl.brain-bican.org/ontology/mbao/MBA_1145 Cerebellar cortex, Purkinje layer http://purl.obolibrary.org/obo/NCBITaxon_1965096 Callithrix http://purl.obolibrary.org/obo/NCBITaxon_9481 Callithrix http://purl.obolibrary.org/obo/NCBITaxon_9984 Oryctolagus http://purl.obolibrary.org/obo/NCBITaxon_9979 Leporidae http://purl.obolibrary.org/obo/CL_0700009 obsolete kidney collecting duct beta-intercalated cell OBSOLETE. A renal beta-intercalated cell that is part of the cortical collecting duct. The medullary collecting duct does not contain the renal beta-intercalated cell type. http://purl.obolibrary.org/obo/GO_0002288 obsolete NK T cell activation involved in immune response OBSOLETE. The change in morphology and behavior of a mature or immature natural killer T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response. http://purl.obolibrary.org/obo/GO_0003674 molecular_function A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs. http://purl.obolibrary.org/obo/GO_0008150 biological_process A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence. http://purl.obolibrary.org/obo/GO_0044237 obsolete cellular metabolic process OBSOLETE. The chemical reactions and pathways by which individual cells transform chemical substances. http://purl.obolibrary.org/obo/GO_0098537 obsolete lobed nucleus OBSOLETE. Nucleus with two or more lobes connected by a thin filament that contains no internal chromatin. Examples include the nuclei of mature basophils, eosinophils and neutrophils in mice and humans. http://purl.obolibrary.org/obo/PR_000001338 complement receptor type 2 A protein that is a translation product of the human CR2 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001808 C/C-C motif small inducible chemokine A protein with core architecture consisting of a Small cytokines (intecrine/chemokine), interleukin-8 like (Pfam:PF00048) domain. http://purl.obolibrary.org/obo/PR_000001971 vascular endothelial growth factor receptor A protein with core architecture consisting of a signal sequence, followed by 7 Ig-like domains (Pfam:PF00047, Pfam:PF07679, or Pfam:PF07686), a transmembrane region, and a cytoplasmic Protein tyrosine kinase domain. http://purl.obolibrary.org/obo/PR_000018263 amino acid chain A molecule that consists of amino acid residues (unmodified amino-acid residues and/or modified amino-acid residues) linked by peptide bonds or derivatives of such bonds. http://purl.obolibrary.org/obo/RO_0002577 system A material entity consisting of multiple components that are causally integrated. http://purl.obolibrary.org/obo/GO_0070999 obsolete detection of mechanical stimulus involved in sensory perception of gravity OBSOLETE. The series of events involved in the perception of gravity in which a sensory mechanical stimulus is received and converted into a molecular signal. http://purl.obolibrary.org/obo/PR_000010543 myeloperoxidase A protein that is a translation product of the human MPO gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/CL_4023067 obsolete Martinotti morphology L2/3 pvalb-like sst GABAergic cortical interneuron (Mus musculus) OBSOLETE A L2/3 pvalb-like sst GABAergic cortical interneuron (Mus musculus) that has Martinotti morphology. http://purl.obolibrary.org/obo/CL_4023100 obsolete L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (Homo sapiens) OBSOLETE. An intratelencephalic-projecting glutamatergic neuron with a soma found in layer 6 of the human primary motor cortex. http://purl.obolibrary.org/obo/CL_2000009 obsolete microvascular endothelium blood vessel endothelial cell Any blood vessel endothelial cell that is part of a microvascular endothelium. http://purl.obolibrary.org/obo/CL_2000026 obsolete cerebellum Golgi cell Any Golgi cell that is part of a cerebellum. http://purl.obolibrary.org/obo/CL_2000050 obsolete retina retinal ganglion cell Any retinal ganglion cell that is part of a retina. http://purl.obolibrary.org/obo/CL_2000082 obsolete melanocyte of foreskin OBSOLETE. Any melanocyte of skin that is part of a skin of prepuce of penis. http://purl.obolibrary.org/obo/CL_4023034 obsolete L2/3 pvalb-like sst GABAergic cortical interneuron (Mus musculus) OBSOLETE A sst GABAergic cortical interneuron transcriptomically between the sst and the pvalb families with a soma found in L2/3. Some L2/3 PV-like sst cells have Martinotti morphology while some have basket cell morphology. L2/3 PV-like sst cells have lower AP width and higher firing rate than typical Sst subclass cells. L2/3 PV-like sst cells have high maximum firing rate variability, with many classified as belonging to the pvalb subclass on the basis of electrophysiology. http://purl.obolibrary.org/obo/CL_0017501 obsolete lobed nucleus Nucleus with two or more lobes connected by a thin filament that contains no internal chromatin. http://purl.obolibrary.org/obo/CL_4023099 obsolete L5 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (Homo sapiens) OBSOLETE. An intratelencephalic-projecting glutamatergic neuron with a soma found in layer 5 of the human primary motor cortex. http://purl.obolibrary.org/obo/CL_4023101 obsolete L5/6 near-projecting glutamatergic neuron of the primary motor cortex (Homo sapiens) OBSOLETE. A near-projecting glutamatergic neuron with a soma found in layer 5/6 of the human primary motor cortex. http://purl.obolibrary.org/obo/CL_4023102 obsolete L5/6 near-projecting glutamatergic neuron of the primary motor cortex (Callithrix jacchus) OBSOLETE. A near-projecting glutamatergic neuron with a soma found in layer 5/6 of the marmoset primary motor cortex. http://purl.obolibrary.org/obo/CL_4023103 obsolete L2/3 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (Callithrix jacchus) OBSOLETE. An intratelencephalic-projecting glutamatergic neuron with a soma found in layer 2/3 of the marmoset primary motor cortex. http://purl.obolibrary.org/obo/CL_4023104 obsolete L5 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (Callithrix jacchus) OBSOLETE An intratelencephalic-projecting glutamatergic neuron with a soma found in layer 5 of the marmoset primary motor cortex. http://purl.obolibrary.org/obo/CL_4023105 obsolete L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (Callithrix jacchus) OBSOLETE. An intratelencephalic-projecting glutamatergic neuron with a soma found in layer 6 of the marmoset primary motor cortex. http://purl.obolibrary.org/obo/CL_4023106 obsolete meis2 expressing cortical GABAergic cell (Callithrix jacchus) OBSOLETE. A mouse GABAergic cell located in the marmoset cerebral cortex that expresses meis2. http://purl.obolibrary.org/obo/CL_4023070 obsolete caudal ganglionic eminence derived GABAergic cortical interneuron OBSOLETE. A GABAergic cortical interneuron that develops from the caudal ganglionic eminence and has migrated to the cerebral cortex. https://purl.brain-bican.org/ontology/mbao/MBA_339 Midbrain, sensory related https://purl.brain-bican.org/ontology/mbao/MBA_987 Pons, motor related http://identifiers.org/ncbigene/268780 Egflam (Mmus) http://identifiers.org/ncbigene/319903 9630013A20Rik (Mmus) http://identifiers.org/ncbigene/16590 Kit (Mmus) http://identifiers.org/ncbigene/212377 Mms22l (Mmus) http://identifiers.org/ncbigene/67791 6530411M01Rik (Mmus) https://purl.brain-bican.org/ontology/mbao/MBA_1080 Hippocampal region https://purl.brain-bican.org/ontology/mbao/MBA_244 Main olfactory bulb, outer plexiform layer https://purl.brain-bican.org/ontology/mbao/MBA_258 Lateral septal nucleus, rostral (rostroventral) part https://purl.brain-bican.org/ontology/mbao/MBA_484682516 corpus callosum, body https://purl.brain-bican.org/ontology/mbao/MBA_956 corpus callosum, anterior forceps http://identifiers.org/ncbigene/66240 Kcne1l (Mmus) http://purl.obolibrary.org/obo/CP_0000000 obsolete CP:0000000 http://purl.obolibrary.org/obo/CP_0000027 obsolete CP:0000027 http://purl.obolibrary.org/obo/CP_0000028 obsolete CP:0000028 http://purl.obolibrary.org/obo/CP_0000035 obsolete CP:0000035 http://purl.obolibrary.org/obo/CP_0000037 obsolete CP:0000037 http://identifiers.org/ncbigene/14560 Gdf10 (Mmus) https://purl.brain-bican.org/ontology/mbao/MBA_983 lateral forebrain bundle system http://identifiers.org/ncbigene/333564 Fndc3c1 (Mmus) https://purl.brain-bican.org/ontology/mbao/MBA_991 medial forebrain bundle system http://identifiers.org/ncbigene/22774 Zic4 (Mmus) http://identifiers.org/ncbigene/216892 Spns2 (Mmus) http://identifiers.org/ncbigene/241159 Neu4 (Mmus) http://identifiers.org/ncbigene/210530 P3h2 (Mmus) http://identifiers.org/ncbigene/13142 Dao (Mmus) http://identifiers.org/ncbigene/14360 Fyn (Mmus) http://identifiers.org/ncbigene/12424 Cck (Mmus) http://identifiers.org/ncbigene/100040736 Foxd2os (Mmus) http://identifiers.org/ncbigene/100042056 9130019P16Rik (Mmus) http://identifiers.org/ncbigene/100043902 Six3os1 (Mmus) http://identifiers.org/ncbigene/100503592 A330076C08Rik (Mmus) http://identifiers.org/ncbigene/100504234 Ccdc170 (Mmus) http://identifiers.org/ncbigene/101100 Ttll3 (Mmus) http://identifiers.org/ncbigene/101772 Ano1 (Mmus) http://identifiers.org/ncbigene/102632457 Gm30524 (Mmus) http://identifiers.org/ncbigene/102635243 Gm32633 (Mmus) http://identifiers.org/ncbigene/102638227 Gm34838 (Mmus) http://identifiers.org/ncbigene/103978 Gpc5 (Mmus) http://identifiers.org/ncbigene/104010 Cdh22 (Mmus) http://identifiers.org/ncbigene/104174 Gldc (Mmus) http://identifiers.org/ncbigene/104245 Slc6a5 (Mmus) http://identifiers.org/ncbigene/104798 Sfta3-ps (Mmus) http://identifiers.org/ncbigene/107376 E330013P04Rik (Mmus) http://identifiers.org/ncbigene/107626 Asmt (Mmus) http://identifiers.org/ncbigene/108000 Cenpf (Mmus) http://identifiers.org/ncbigene/108068 Grm2 (Mmus) http://identifiers.org/ncbigene/108069 Grm3 (Mmus) http://identifiers.org/ncbigene/108073 Grm7 (Mmus) http://identifiers.org/ncbigene/109272 Mybpc1 (Mmus) http://identifiers.org/ncbigene/109979 Art3 (Mmus) http://identifiers.org/ncbigene/110648 Lmx1a (Mmus) http://identifiers.org/ncbigene/110862 Kcnq3 (Mmus) http://identifiers.org/ncbigene/114873 Dscaml1 (Mmus) http://identifiers.org/ncbigene/11540 Adora2a (Mmus) http://identifiers.org/ncbigene/11606 Agt (Mmus) http://identifiers.org/ncbigene/11668 Aldh1a1 (Mmus) http://identifiers.org/ncbigene/11682 Alk (Mmus) http://identifiers.org/ncbigene/116847 Prelp (Mmus) http://identifiers.org/ncbigene/116849 Iltifb (Mmus) http://identifiers.org/ncbigene/11815 Apod (Mmus) http://identifiers.org/ncbigene/11816 Apoe (Mmus) http://identifiers.org/ncbigene/11826 Aqp1 (Mmus) http://identifiers.org/ncbigene/11829 Aqp4 (Mmus) http://identifiers.org/ncbigene/118446 Gjc3 (Mmus) http://identifiers.org/ncbigene/12111 Bgn (Mmus) http://identifiers.org/ncbigene/12159 Bmp4 (Mmus) http://identifiers.org/ncbigene/12161 Bmp6 (Mmus) http://identifiers.org/ncbigene/12192 Zfp36l1 (Mmus) http://identifiers.org/ncbigene/12259 C1qa (Mmus) http://identifiers.org/ncbigene/12268 C4b (Mmus) http://identifiers.org/ncbigene/12290 Cacna1e (Mmus) http://identifiers.org/ncbigene/12322 Camk2a (Mmus) http://identifiers.org/ncbigene/12374 Casr (Mmus) http://identifiers.org/ncbigene/12494 Cd38 (Mmus) http://identifiers.org/ncbigene/12550 Cdh1 (Mmus) http://identifiers.org/ncbigene/12615 Cenpa (Mmus) http://identifiers.org/ncbigene/12741 Cldn5 (Mmus) http://identifiers.org/ncbigene/12951 Crx (Mmus) http://identifiers.org/ncbigene/12971 Crym (Mmus) http://identifiers.org/ncbigene/13176 Dcc (Mmus) http://identifiers.org/ncbigene/13195 Ddc (Mmus) http://identifiers.org/ncbigene/13199 Ddn (Mmus) http://identifiers.org/ncbigene/13371 Dio2 (Mmus) http://identifiers.org/ncbigene/13411 Dnah11 (Mmus) http://identifiers.org/ncbigene/13488 Drd1 (Mmus) http://identifiers.org/ncbigene/13618 Ednrb (Mmus) http://identifiers.org/ncbigene/13649 Egfr (Mmus) http://identifiers.org/ncbigene/13865 Nr2f1 (Mmus) http://identifiers.org/ncbigene/14013 Mecom (Mmus) http://identifiers.org/ncbigene/140919 Slc17a6 (Mmus) http://identifiers.org/ncbigene/14165 Fgf10 (Mmus) http://identifiers.org/ncbigene/14281 Fos (Mmus) http://identifiers.org/ncbigene/14400 Gabrb1 (Mmus) http://identifiers.org/ncbigene/14412 Slc6a13 (Mmus) http://identifiers.org/ncbigene/14415 Gad1 (Mmus) http://identifiers.org/ncbigene/14417 Gad2 (Mmus) http://identifiers.org/ncbigene/14432 Gap43 (Mmus) http://identifiers.org/ncbigene/14609 Gja1 (Mmus) http://identifiers.org/ncbigene/14695 Gnb3 (Mmus) http://identifiers.org/ncbigene/14699 Gngt1 (Mmus) http://identifiers.org/ncbigene/14710 Gngt2 (Mmus) http://identifiers.org/ncbigene/14714 Gnrh1 (Mmus) http://identifiers.org/ncbigene/14724 Gp1bb (Mmus) http://identifiers.org/ncbigene/14765 Gpr50 (Mmus) http://identifiers.org/ncbigene/14799 Gria1 (Mmus) http://identifiers.org/ncbigene/14803 Grid1 (Mmus) http://identifiers.org/ncbigene/14811 Grin2a (Mmus) http://identifiers.org/ncbigene/14813 Grin2c (Mmus) http://identifiers.org/ncbigene/14870 Gstp1 (Mmus) http://identifiers.org/ncbigene/15186 Hdc (Mmus) http://identifiers.org/ncbigene/15221 Foxd3 (Mmus) http://identifiers.org/ncbigene/15228 Foxg1 (Mmus) http://identifiers.org/ncbigene/15364 Hmga2 (Mmus) http://identifiers.org/ncbigene/15478 Hs3st3a1 (Mmus) http://identifiers.org/ncbigene/15483 Hsd11b1 (Mmus) http://identifiers.org/ncbigene/16008 Igfbp2 (Mmus) http://identifiers.org/ncbigene/16011 Igfbp5 (Mmus) http://identifiers.org/ncbigene/16323 Inhba (Mmus) http://identifiers.org/ncbigene/16372 Irx2 (Mmus) http://identifiers.org/ncbigene/16426 Itih3 (Mmus) http://identifiers.org/ncbigene/16870 Lhx2 (Mmus) http://identifiers.org/ncbigene/16956 Lpl (Mmus) http://identifiers.org/ncbigene/17068 Ly6d (Mmus) http://identifiers.org/ncbigene/170790 Mlc1 (Mmus) http://identifiers.org/ncbigene/171211 Edaradd (Mmus) http://identifiers.org/ncbigene/17132 Maf (Mmus) http://identifiers.org/ncbigene/171469 Gpr37l1 (Mmus) http://identifiers.org/ncbigene/17155 Man1a (Mmus) http://identifiers.org/ncbigene/17219 Mcm6 (Mmus) http://identifiers.org/ncbigene/17300 Foxc1 (Mmus) http://identifiers.org/ncbigene/17304 Mfge8 (Mmus) http://identifiers.org/ncbigene/17345 Mki67 (Mmus) http://identifiers.org/ncbigene/17441 Mog (Mmus) http://identifiers.org/ncbigene/17533 Mrc1 (Mmus) http://identifiers.org/ncbigene/17536 Meis2 (Mmus) http://identifiers.org/ncbigene/18133 Ccn3 (Mmus) http://identifiers.org/ncbigene/18417 Cldn11 (Mmus) http://identifiers.org/ncbigene/18424 Otx2 (Mmus) http://identifiers.org/ncbigene/18479 Pak1 (Mmus) http://identifiers.org/ncbigene/18488 Cntn3 (Mmus) http://identifiers.org/ncbigene/18504 Pax2 (Mmus) http://identifiers.org/ncbigene/18545 Pcp2 (Mmus) http://identifiers.org/ncbigene/18553 Pcsk6 (Mmus) http://identifiers.org/ncbigene/18588 Pde6g (Mmus) http://identifiers.org/ncbigene/18595 Pdgfra (Mmus) http://identifiers.org/ncbigene/18610 Pdyn (Mmus) http://identifiers.org/ncbigene/19049 Ppp1r1b (Mmus) http://identifiers.org/ncbigene/19051 Ppp1r17 (Mmus) http://identifiers.org/ncbigene/19216 Ptger1 (Mmus) http://identifiers.org/ncbigene/19227 Pthlh (Mmus) http://identifiers.org/ncbigene/19263 Ptprb (Mmus) http://identifiers.org/ncbigene/19293 Pvalb (Mmus) http://identifiers.org/ncbigene/19734 Rgs16 (Mmus) http://identifiers.org/ncbigene/20200 S100a6 (Mmus) http://identifiers.org/ncbigene/20284 Scrg1 (Mmus) http://identifiers.org/ncbigene/20311 Cxcl5 (Mmus) http://identifiers.org/ncbigene/20315 Cxcl12 (Mmus) http://identifiers.org/ncbigene/20363 Selenop (Mmus) http://identifiers.org/ncbigene/20377 Sfrp1 (Mmus) http://identifiers.org/ncbigene/20378 Frzb (Mmus) http://identifiers.org/ncbigene/20440 St6gal1 (Mmus) http://identifiers.org/ncbigene/20491 Sla (Mmus) http://identifiers.org/ncbigene/20743 Sptbn2 (Mmus) http://identifiers.org/ncbigene/208613 Tmem212 (Mmus) http://identifiers.org/ncbigene/208936 Adamts18 (Mmus) http://identifiers.org/ncbigene/213435 Mylk3 (Mmus) http://identifiers.org/ncbigene/213783 Plekhg1 (Mmus) http://identifiers.org/ncbigene/21386 Tbx3 (Mmus) http://identifiers.org/ncbigene/21416 Tcf7l2 (Mmus) http://identifiers.org/ncbigene/21418 Tfap2a (Mmus) http://identifiers.org/ncbigene/21419 Tfap2b (Mmus) http://identifiers.org/ncbigene/215378 Brinp3 (Mmus) http://identifiers.org/ncbigene/216227 Slc17a8 (Mmus) http://identifiers.org/ncbigene/216616 Efemp1 (Mmus) http://identifiers.org/ncbigene/218194 Phactr1 (Mmus) http://identifiers.org/ncbigene/21824 Thbd (Mmus) http://identifiers.org/ncbigene/21828 Thbs4 (Mmus) http://identifiers.org/ncbigene/218772 Rarb (Mmus) http://identifiers.org/ncbigene/21973 Top2a (Mmus) http://identifiers.org/ncbigene/21990 Tph1 (Mmus) http://identifiers.org/ncbigene/22139 Ttr (Mmus) http://identifiers.org/ncbigene/22283 Ush2a (Mmus) http://identifiers.org/ncbigene/223332 Ranbp3l (Mmus) http://identifiers.org/ncbigene/22348 Slc32a1 (Mmus) http://identifiers.org/ncbigene/223843 Dbx2 (Mmus) http://identifiers.org/ncbigene/223970 Rmi2 (Mmus) http://identifiers.org/ncbigene/224079 Atp13a4 (Mmus) http://identifiers.org/ncbigene/226115 Opalin (Mmus) http://identifiers.org/ncbigene/226250 Afap1l2 (Mmus) http://identifiers.org/ncbigene/227580 C1ql3 (Mmus) http://identifiers.org/ncbigene/22771 Zic1 (Mmus) http://identifiers.org/ncbigene/228731 Nkx2-4 (Mmus) http://identifiers.org/ncbigene/230726 Rhbdl2 (Mmus) http://identifiers.org/ncbigene/232174 Cyp26b1 (Mmus) http://identifiers.org/ncbigene/232685 Lncpint (Mmus) http://identifiers.org/ncbigene/233537 Gdpd4 (Mmus) http://identifiers.org/ncbigene/234258 Neil3 (Mmus) http://identifiers.org/ncbigene/235130 Adamts15 (Mmus) http://identifiers.org/ncbigene/237979 Sdk2 (Mmus) http://identifiers.org/ncbigene/23829 C1ql1 (Mmus) http://identifiers.org/ncbigene/23876 Fbln5 (Mmus) http://identifiers.org/ncbigene/239337 Adamts12 (Mmus) http://identifiers.org/ncbigene/239405 Rspo2 (Mmus) http://identifiers.org/ncbigene/240479 Dipk1c (Mmus) http://identifiers.org/ncbigene/241489 Pde11a (Mmus) http://identifiers.org/ncbigene/242253 Wdr63 (Mmus) http://identifiers.org/ncbigene/242425 Gabbr2 (Mmus) http://identifiers.org/ncbigene/242735 Lrrc38 (Mmus) http://identifiers.org/ncbigene/243369 Sspo (Mmus) http://identifiers.org/ncbigene/243937 Zfp536 (Mmus) http://identifiers.org/ncbigene/244954 Prss35 (Mmus) http://identifiers.org/ncbigene/245827 Fat2 (Mmus) http://identifiers.org/ncbigene/246049 Slc36a2 (Mmus) http://identifiers.org/ncbigene/26558 Homer3 (Mmus) http://identifiers.org/ncbigene/26563 Ror1 (Mmus) http://identifiers.org/ncbigene/268527 Greb1 (Mmus) http://identifiers.org/ncbigene/268709 Fam107a (Mmus) http://identifiers.org/ncbigene/268816 Mroh5 (Mmus) http://identifiers.org/ncbigene/269019 Stk32a (Mmus) http://identifiers.org/ncbigene/269275 Acvr1c (Mmus) http://identifiers.org/ncbigene/269629 Lhfpl3 (Mmus) http://identifiers.org/ncbigene/26968 Islr (Mmus) http://identifiers.org/ncbigene/270150 Ccdc153 (Mmus) http://identifiers.org/ncbigene/27428 Shroom3 (Mmus) http://identifiers.org/ncbigene/276952 Rasl10b (Mmus) http://identifiers.org/ncbigene/277468 Slc39a12 (Mmus) http://identifiers.org/ncbigene/278304 Zfp385c (Mmus) http://identifiers.org/ncbigene/30952 Cngb3 (Mmus) http://identifiers.org/ncbigene/319922 Vwc2 (Mmus) http://identifiers.org/ncbigene/319951 A230001M10Rik (Mmus) http://identifiers.org/ncbigene/319984 Jph4 (Mmus) http://identifiers.org/ncbigene/320772 Mdga2 (Mmus) http://identifiers.org/ncbigene/320784 C230072F16Rik (Mmus) http://identifiers.org/ncbigene/320981 Enpp6 (Mmus) http://identifiers.org/ncbigene/328354 Gm5087 (Mmus) http://identifiers.org/ncbigene/329078 Emx2os (Mmus) http://identifiers.org/ncbigene/329274 Fam163a (Mmus) http://identifiers.org/ncbigene/338521 Fa2h (Mmus) http://identifiers.org/ncbigene/373864 Col27a1 (Mmus) http://identifiers.org/ncbigene/381112 Arhgef33 (Mmus) http://identifiers.org/ncbigene/384071 Slc25a34 (Mmus) http://identifiers.org/ncbigene/407831 Tmem204 (Mmus) http://identifiers.org/ncbigene/433022 Plcxd2 (Mmus) http://identifiers.org/ncbigene/50768 Dlc1 (Mmus) http://identifiers.org/ncbigene/50779 Rgs6 (Mmus) http://identifiers.org/ncbigene/50914 Olig1 (Mmus) http://identifiers.org/ncbigene/50929 Il22 (Mmus) http://identifiers.org/ncbigene/53896 Slc7a10 (Mmus) http://identifiers.org/ncbigene/54216 Pcdh7 (Mmus) http://identifiers.org/ncbigene/54612 Sfrp5 (Mmus) http://identifiers.org/ncbigene/56213 Htra1 (Mmus) http://identifiers.org/ncbigene/56410 Cbln3 (Mmus) http://identifiers.org/ncbigene/56744 Pf4 (Mmus) http://identifiers.org/ncbigene/56747 Sez6l (Mmus) http://identifiers.org/ncbigene/57265 Fzd2 (Mmus) http://identifiers.org/ncbigene/574402 Gpr17 (Mmus) http://identifiers.org/ncbigene/57915 Tbc1d1 (Mmus) http://identifiers.org/ncbigene/58807 Slco1c1 (Mmus) http://identifiers.org/ncbigene/59058 Bhlhe22 (Mmus) http://identifiers.org/ncbigene/620376 Gm6145 (Mmus) http://identifiers.org/ncbigene/624549 Gm29683 (Mmus) http://identifiers.org/ncbigene/626082 Gm20754 (Mmus) http://identifiers.org/ncbigene/629147 Ctxn3 (Mmus) http://identifiers.org/ncbigene/63830 Kcnq1ot1 (Mmus) http://identifiers.org/ncbigene/64085 Clstn2 (Mmus) http://identifiers.org/ncbigene/65969 Cubn (Mmus) http://identifiers.org/ncbigene/66214 Rgcc (Mmus) http://identifiers.org/ncbigene/66270 Retreg1 (Mmus) http://identifiers.org/ncbigene/66402 Sln (Mmus) http://identifiers.org/ncbigene/66425 Pcp4l1 (Mmus) http://identifiers.org/ncbigene/665119 Sec14l5 (Mmus) http://identifiers.org/ncbigene/66540 Fam107b (Mmus) http://identifiers.org/ncbigene/66673 Sorcs3 (Mmus) http://identifiers.org/ncbigene/667742 Piezo2 (Mmus) http://identifiers.org/ncbigene/66905 Plin3 (Mmus) http://identifiers.org/ncbigene/66977 Nuf2 (Mmus) http://identifiers.org/ncbigene/67473 Slc47a1 (Mmus) http://identifiers.org/ncbigene/67801 Pllp (Mmus) http://identifiers.org/ncbigene/67844 Rab32 (Mmus) http://identifiers.org/ncbigene/68026 Pclaf (Mmus) http://identifiers.org/ncbigene/68070 Pdzd2 (Mmus) http://identifiers.org/ncbigene/68178 Cgnl1 (Mmus) http://identifiers.org/ncbigene/68458 Ppp1r14a (Mmus) http://identifiers.org/ncbigene/68743 Anln (Mmus) http://identifiers.org/ncbigene/70134 2210011C24Rik (Mmus) http://identifiers.org/ncbigene/71481 Alpk1 (Mmus) http://identifiers.org/ncbigene/71660 Rarres2 (Mmus) http://identifiers.org/ncbigene/72258 Kcnk10 (Mmus) http://identifiers.org/ncbigene/72446 Prr5l (Mmus) http://identifiers.org/ncbigene/72555 Shisa9 (Mmus) http://identifiers.org/ncbigene/72902 Spock3 (Mmus) http://identifiers.org/ncbigene/72927 Hepacam (Mmus) http://identifiers.org/ncbigene/72961 Slc17a7 (Mmus) http://identifiers.org/ncbigene/73940 Hapln2 (Mmus) http://identifiers.org/ncbigene/74145 F13a1 (Mmus) http://identifiers.org/ncbigene/74318 Hopx (Mmus) http://identifiers.org/ncbigene/74563 Rasgef1c (Mmus) http://identifiers.org/ncbigene/75396 Spp2 (Mmus) http://identifiers.org/ncbigene/75465 Dynlrb2 (Mmus) http://identifiers.org/ncbigene/76422 Mroh3 (Mmus) http://identifiers.org/ncbigene/76453 Prss23 (Mmus) http://identifiers.org/ncbigene/77018 Col25a1 (Mmus) http://identifiers.org/ncbigene/77125 Il33 (Mmus) http://identifiers.org/ncbigene/77808 Gm44196 (Mmus) http://identifiers.org/ncbigene/78748 Rassf10 (Mmus) http://identifiers.org/ncbigene/78754 Galnt15 (Mmus) http://identifiers.org/ncbigene/80837 Rhoj (Mmus) http://identifiers.org/ncbigene/83430 Il23a (Mmus) http://identifiers.org/ncbigene/83453 Chrdl1 (Mmus) http://identifiers.org/ncbigene/83921 Cemip2 (Mmus) http://identifiers.org/ncbigene/96875 Prg4 (Mmus) http://identifiers.org/ncbigene/98267 Stk17b (Mmus) http://identifiers.org/ncbigene/98363 Efhd1 (Mmus) https://purl.brain-bican.org/ontology/mbao/MBA_348 Midbrain, behavioral state related https://purl.brain-bican.org/ontology/mbao/MBA_386 Medulla, sensory related https://purl.brain-bican.org/ontology/mbao/MBA_960 cerebellum related fiber tracts http://identifiers.org/ensembl/ENSG00000006128 TAC1 http://identifiers.org/ensembl/ENSG00000010327 STAB1 http://identifiers.org/ensembl/ENSG00000038295 TLL1 http://identifiers.org/ensembl/ENSG00000038945 MSR1 http://identifiers.org/ensembl/ENSG00000041982 TNC http://identifiers.org/ensembl/ENSG00000047648 ARHGAP6 http://identifiers.org/ensembl/ENSG00000047936 ROS1 http://identifiers.org/ensembl/ENSG00000050730 TNIP3 http://identifiers.org/ensembl/ENSG00000051128 HOMER3 http://identifiers.org/ensembl/ENSG00000053747 LAMA3 http://identifiers.org/ensembl/ENSG00000072694 FCGR2B http://identifiers.org/ensembl/ENSG00000078898 BPIFB2 http://identifiers.org/ensembl/ENSG00000079691 CARMIL1 http://identifiers.org/ensembl/ENSG00000082293 COL19A1 http://identifiers.org/ensembl/ENSG00000082482 KCNK2 http://identifiers.org/ensembl/ENSG00000082684 SEMA5B http://identifiers.org/ensembl/ENSG00000100292 HMOX1 http://identifiers.org/ensembl/ENSG00000100362 PVALB http://identifiers.org/ensembl/ENSG00000100604 CHGA http://identifiers.org/ensembl/ENSG00000101134 DOK5 http://identifiers.org/ensembl/ENSG00000107796 ACTA2 http://identifiers.org/ensembl/ENSG00000111215 PRR4 http://identifiers.org/ensembl/ENSG00000113532 ST8SIA4 http://identifiers.org/ensembl/ENSG00000114805 PLCH1 http://identifiers.org/ensembl/ENSG00000115593 SMYD1 http://identifiers.org/ensembl/ENSG00000118513 MYB http://identifiers.org/ensembl/ENSG00000118523 CCN2 http://identifiers.org/ensembl/ENSG00000119547 ONECUT2 http://identifiers.org/ensembl/ENSG00000122585 NPY http://identifiers.org/ensembl/ENSG00000122852 SFTPA1 http://identifiers.org/ensembl/ENSG00000124302 CHST8 http://identifiers.org/ensembl/ENSG00000124491 F13A1 http://identifiers.org/ensembl/ENSG00000125869 LAMP5 http://identifiers.org/ensembl/ENSG00000128536 CDHR3 http://identifiers.org/ensembl/ENSG00000131097 HIGD1B http://identifiers.org/ensembl/ENSG00000131471 AOC3 http://identifiers.org/ensembl/ENSG00000131747 TOP2A http://identifiers.org/ensembl/ENSG00000134138 MEIS2 http://identifiers.org/ensembl/ENSG00000134443 GRP http://identifiers.org/ensembl/ENSG00000137252 HCRTR2 http://identifiers.org/ensembl/ENSG00000137573 SULF1 http://identifiers.org/ensembl/ENSG00000137709 POU2F3 http://identifiers.org/ensembl/ENSG00000137804 NUSAP1 http://identifiers.org/ensembl/ENSG00000139329 LUM http://identifiers.org/ensembl/ENSG00000140538 NTRK3 http://identifiers.org/ensembl/ENSG00000143171 RXRG http://identifiers.org/ensembl/ENSG00000143196 DPT http://identifiers.org/ensembl/ENSG00000144227 NXPH2 http://identifiers.org/ensembl/ENSG00000144229 THSD7B http://identifiers.org/ensembl/ENSG00000145730 PAM http://identifiers.org/ensembl/ENSG00000146469 VIP http://identifiers.org/ensembl/ENSG00000149591 TAGLN http://identifiers.org/ensembl/ENSG00000152818 UTRN http://identifiers.org/ensembl/ENSG00000154080 CHST9 http://identifiers.org/ensembl/ENSG00000154102 C16orf74 http://identifiers.org/ensembl/ENSG00000156395 SORCS3 http://identifiers.org/ensembl/ENSG00000156689 GLYATL2 http://identifiers.org/ensembl/ENSG00000157005 SST http://identifiers.org/ensembl/ENSG00000157404 KIT http://identifiers.org/ensembl/ENSG00000162399 BSND http://identifiers.org/ensembl/ENSG00000163377 TAFA4 http://identifiers.org/ensembl/ENSG00000163735 CXCL5 http://identifiers.org/ensembl/ENSG00000164120 HPGD http://identifiers.org/ensembl/ENSG00000164330 EBF1 http://identifiers.org/ensembl/ENSG00000166803 PCLAF http://identifiers.org/ensembl/ENSG00000166959 MS4A8 http://identifiers.org/ensembl/ENSG00000167306 MYO5B http://identifiers.org/ensembl/ENSG00000168079 SCARA5 http://identifiers.org/ensembl/ENSG00000170323 FABP4 http://identifiers.org/ensembl/ENSG00000171303 KCNK3 http://identifiers.org/ensembl/ENSG00000171346 KRT15 http://identifiers.org/ensembl/ENSG00000171587 DSCAM http://identifiers.org/ensembl/ENSG00000171848 RRM2 http://identifiers.org/ensembl/ENSG00000171951 SCG2 http://identifiers.org/ensembl/ENSG00000172673 THEMIS http://identifiers.org/ensembl/ENSG00000174501 ANKRD36C http://identifiers.org/ensembl/ENSG00000174807 CD248 http://identifiers.org/ensembl/ENSG00000174948 GPR149 http://identifiers.org/ensembl/ENSG00000175063 UBE2C http://identifiers.org/ensembl/ENSG00000175497 DPP10 http://identifiers.org/ensembl/ENSG00000176009 ASCL3 http://identifiers.org/ensembl/ENSG00000178031 ADAMTSL1 http://identifiers.org/ensembl/ENSG00000178538 CA8 http://identifiers.org/ensembl/ENSG00000178568 ERBB4 http://identifiers.org/ensembl/ENSG00000179902 C1orf194 http://identifiers.org/ensembl/ENSG00000180801 ARSJ http://identifiers.org/ensembl/ENSG00000183662 TAFA1 http://identifiers.org/ensembl/ENSG00000184005 ST6GALNAC3 http://identifiers.org/ensembl/ENSG00000184530 C6orf58 http://identifiers.org/ensembl/ENSG00000185668 POU3F1 http://identifiers.org/ensembl/ENSG00000185942 NKAIN3 http://identifiers.org/ensembl/ENSG00000187908 DMBT1 http://identifiers.org/ensembl/ENSG00000189056 RELN http://identifiers.org/ensembl/ENSG00000189058 APOD http://identifiers.org/ensembl/ENSG00000196090 PTPRT http://identifiers.org/ensembl/ENSG00000196569 LAMA2 http://identifiers.org/ensembl/ENSG00000197085 NPSR1-AS1 http://identifiers.org/ensembl/ENSG00000197353 LYPD2 http://identifiers.org/ensembl/ENSG00000197943 PLCG2 http://identifiers.org/ensembl/ENSG00000198691 ABCA4 http://identifiers.org/ensembl/ENSG00000198901 PRC1 http://identifiers.org/ensembl/ENSG00000198963 RORB http://identifiers.org/ensembl/ENSG00000204262 COL5A2 http://identifiers.org/ensembl/ENSG00000204305 AGER http://identifiers.org/ensembl/ENSG00000206073 SERPINB4 http://identifiers.org/ensembl/ENSG00000215182 MUC5AC http://identifiers.org/ensembl/ENSG00000227681 AL033504.1 http://identifiers.org/ensembl/ENSG00000235665 LINC00298 http://identifiers.org/ensembl/ENSG00000242021 AC112493.1 http://identifiers.org/ensembl/ENSG00000242265 PEG10 http://identifiers.org/ensembl/ENSG00000243004 ENSG00000243004;AC005062.2;AC005062.1 http://identifiers.org/ensembl/ENSG00000249803 AC112178.1 http://identifiers.org/ensembl/ENSG00000250971 AC110772.2 http://identifiers.org/ensembl/ENSG00000256193 LINC00507 http://identifiers.org/ensembl/ENSG00000264630 PRKCA-AS1 http://identifiers.org/ensembl/ENSG00000265485 LINC01915 http://identifiers.org/ensembl/ENSG00000267109 AC011990.1 http://identifiers.org/ensembl/ENSG00000271860 AL589740.1 http://identifiers.org/ensembl/ENSG00000275443 AC012409.2 http://identifiers.org/ensembl/ENSG00000278254 AC004852.2 http://purl.obolibrary.org/obo/CL_4023083 obsolete chandelier cell http://identifiers.org/ensembl/ENSMUSG00000109994 Gm45459 (Mmus) http://identifiers.org/ncbigene/10716 TBR1 http://identifiers.org/ncbigene/11281 POU6F2 http://identifiers.org/ncbigene/1310 COL19A1 http://identifiers.org/ncbigene/131034 CPNE4 http://identifiers.org/ncbigene/1395 CRHR2 http://identifiers.org/ncbigene/1812 DRD1 http://identifiers.org/ncbigene/1813 DRD2 http://identifiers.org/ncbigene/24141 LAMP5 http://identifiers.org/ncbigene/2571 GAD1 http://identifiers.org/ncbigene/2572 GAD2 http://identifiers.org/ncbigene/26468 LHX6 http://identifiers.org/ncbigene/27086 FOXP1 http://identifiers.org/ncbigene/2893 GRIA4 http://identifiers.org/ncbigene/2897 GRIK1 http://identifiers.org/ncbigene/29091 STXBP6 http://identifiers.org/ncbigene/30820 KCNIP1 http://identifiers.org/ncbigene/3736 KCNA1 http://identifiers.org/ncbigene/395 ARHGAP6 http://identifiers.org/ncbigene/4212 MEIS2 http://identifiers.org/ncbigene/4852 NPY http://identifiers.org/ncbigene/4861 NPAS1 http://identifiers.org/ncbigene/4929 NR4A2 http://identifiers.org/ncbigene/5079 PAX5 http://identifiers.org/ncbigene/54796 BNC2 http://identifiers.org/ncbigene/55553 SOX6 http://identifiers.org/ncbigene/57084 SLC17A6 http://identifiers.org/ncbigene/5744 PTHLH http://identifiers.org/ncbigene/5816 PVALB http://identifiers.org/ncbigene/64919 BCL11B http://identifiers.org/ncbigene/6496 SIX3 http://identifiers.org/ncbigene/6531 SLC6A3 http://identifiers.org/ncbigene/6752 SSTR2 http://identifiers.org/ncbigene/7054 TH http://identifiers.org/ncbigene/7432 VIP http://identifiers.org/ncbigene/793 CALB1 http://identifiers.org/ncbigene/93986 FOXP2 http://identifiers.org/ncbigene/9547 CXCL14 http://identifiers.org/ncbigene/9705 ST18 http://identifiers.org/ncbigene/381925 Plpp4 (Mmus) https://purl.brain-bican.org/ontology/mbao/MBA_370 Medulla, motor related http://identifiers.org/ncbigene/51797 Ctps (Mmus) http://identifiers.org/ncbigene/14652 Glp1r (Mmus) http://identifiers.org/ncbigene/67701 Wfdc2 (Mmus) http://identifiers.org/ncbigene/19144 Klk6 (Mmus) http://identifiers.org/ncbigene/66353 Riiad1 (Mmus) http://identifiers.org/ncbigene/76088 Dock8 (Mmus) http://identifiers.org/ncbigene/76438 Rftn1 (Mmus) https://purl.brain-bican.org/ontology/mbao/MBA_728 arbor vitae http://purl.obolibrary.org/obo/CL_0008023 obsolete cardiac fibroblast http://purl.obolibrary.org/obo/CP_0000025 obsolete CP:0000025 http://purl.obolibrary.org/obo/CP_0000039 obsolete CP:0000039 http://purl.obolibrary.org/obo/CP_0000040 obsolete CP:0000040 http://purl.obolibrary.org/obo/CP_0000043 obsolete CP:0000043 http://purl.obolibrary.org/obo/D96882F1-8709-49AB-BCA9-772A67EA6C33 obsolete D96882F1-8709-49AB-BCA9-772A67EA6C33 https://purl.brain-bican.org/ontology/mbao/MBA_1117 Pons, behavioral state related http://identifiers.org/ncbigene/58187 Cldn10 (Mmus) https://purl.brain-bican.org/ontology/mbao/MBA_1132 Pons, sensory related https://purl.brain-bican.org/ontology/mbao/MBA_21 lateral olfactory tract, general https://purl.brain-bican.org/ontology/mbao/MBA_323 Midbrain, motor related http://identifiers.org/ncbigene/216961 Coro6 (Mmus) http://identifiers.org/ncbigene/75823 Fam227b (Mmus) http://identifiers.org/ncbigene/16840 Cnmd (Mmus) http://identifiers.org/ncbigene/69239 Pdzph1 (Mmus) http://identifiers.org/ncbigene/109648 Npy (Mmus) http://identifiers.org/ncbigene/14580 Gfap (Mmus) https://purl.brain-bican.org/ontology/mbao/MBA_856 Thalamus, polymodal association cortex related http://identifiers.org/ncbigene/20963 Syk (Mmus) http://purl.obolibrary.org/obo/CLM_5050484 LAMP5, CXCL14 (CAS evidence). http://purl.obolibrary.org/obo/CLM_5050485 LAMP5, LHX6 (CAS evidence). http://purl.obolibrary.org/obo/CLM_5050493 GAD1, GAD2, FOXP2, MEIS2, NPAS1 (CAS evidence). http://purl.obolibrary.org/obo/CLM_5050494 SOX6, KCNA1 (CAS evidence). http://purl.obolibrary.org/obo/CLM_5050495 Pvalb (CAS evidence). http://purl.obolibrary.org/obo/CLM_5050496 Sst, Tbr1, Slc17a6 (CAS evidence). http://purl.obolibrary.org/obo/CLM_5050504 DRD1, CPNE4 (CAS evidence). http://purl.obolibrary.org/obo/CLM_5050509 TH, CALB1, SLC6A3, NR4A2, BNC2 (CAS evidence). http://purl.obolibrary.org/obo/CLM_5050511 TH, GAD2 (CAS evidence). http://purl.obolibrary.org/obo/CLM_5050512 PAX5, BCL11B, POU6F2 (CAS evidence). http://purl.obolibrary.org/obo/CLM_5050513 SIX3, FOXP1 (CAS evidence). http://purl.obolibrary.org/obo/CLM_5050515 TH, SOX6 (CAS evidence). http://purl.obolibrary.org/obo/CLM_5050520 ST18, PTHLH, COL19A1 (CAS evidence). http://purl.obolibrary.org/obo/CLM_5050523 NPY (CAS evidence). http://purl.obolibrary.org/obo/CLM_5050525 ST18 (CAS evidence). http://purl.obolibrary.org/obo/CLM_5050527 VIP (CAS evidence). http://purl.obolibrary.org/obo/CLM_5050529 DRD1, STXBP6 (CAS evidence). http://purl.obolibrary.org/obo/CLM_5050530 DRD1, KCNIP1 (CAS evidence). http://purl.obolibrary.org/obo/CLM_5050531 DRD1, DRD2, CRHR2, GRIK1 (CAS evidence). http://purl.obolibrary.org/obo/CLM_5050532 DRD2, STXBP6 (CAS evidence). http://purl.obolibrary.org/obo/CLM_5050534 DRD2, KCNIP1 (CAS evidence). http://purl.obolibrary.org/obo/CLM_5050536 DRD1, ARHGAP6 (CAS evidence). http://purl.obolibrary.org/obo/CLM_5050537 DRD1, GRIA4 (CAS evidence). http://purl.obolibrary.org/obo/CLM_5050538 DRD2, ARHGAP6 (CAS evidence). http://purl.obolibrary.org/obo/CLM_5050544 SLC17A6 (CAS evidence). https://purl.brain-bican.org/ontology/dhbao/DHBA_10343 external segment of globus pallidus https://purl.brain-bican.org/ontology/dhbao/DHBA_10301 subicular cortex https://purl.brain-bican.org/ontology/dhbao/DHBA_10406 lateral nuclear complex of thalamus https://purl.brain-bican.org/ontology/dhbao/DHBA_10416 ventral group of lateral nucleus https://purl.brain-bican.org/ontology/dhbao/DHBA_10465 subthalamus https://purl.brain-bican.org/ontology/dhbao/DHBA_10468 preoptic region of HTH https://purl.brain-bican.org/ontology/dhbao/DHBA_10469 periventricular nucleus, preoptic portion https://purl.brain-bican.org/ontology/dhbao/DHBA_10473 supraoptic region of HTH https://purl.brain-bican.org/ontology/dhbao/DHBA_10483 tuberal region of HTH https://purl.brain-bican.org/ontology/dhbao/DHBA_10506 transient structures of forebrain https://purl.brain-bican.org/ontology/dhbao/DHBA_10558 forebrain commissural fiber tracts https://purl.brain-bican.org/ontology/dhbao/DHBA_146034908 adjoining structures of forebrain ventricles https://purl.brain-bican.org/ontology/dhbao/DHBA_10609 surface structures of forebrain https://purl.brain-bican.org/ontology/dhbao/DHBA_10611 primary sulci https://purl.brain-bican.org/ontology/dhbao/DHBA_10652 surface structures of midbrain https://purl.brain-bican.org/ontology/dhbao/DHBA_10663 transient structures of hindbrain https://purl.brain-bican.org/ontology/dhbao/DHBA_10669 ventricles of hindbrain https://purl.brain-bican.org/ontology/dhbao/DHBA_10670 surface structures of hindbrain https://purl.brain-bican.org/ontology/dhbao/DHBA_12074 olfactory striae https://purl.brain-bican.org/ontology/dhbao/DHBA_12112 cerebral gyri and lobules https://purl.brain-bican.org/ontology/dhbao/DHBA_12196 efferent nuclei of the cranial nerves in the midbrain https://purl.brain-bican.org/ontology/dhbao/DHBA_146034938 ventral tegmental region of midbrain https://purl.brain-bican.org/ontology/dhbao/DHBA_12277 other nuclei in midbrain tegmentum https://purl.brain-bican.org/ontology/dhbao/DHBA_12314 transient structures of midbrain https://purl.brain-bican.org/ontology/dhbao/DHBA_12319 intermediate (mantle) zone of midbrain https://purl.brain-bican.org/ontology/dhbao/DHBA_12417 efferent nuclei of cranial nerves in pons https://purl.brain-bican.org/ontology/dhbao/DHBA_12436 afferent nuclei of cranial nerves in pons https://purl.brain-bican.org/ontology/dhbao/DHBA_12453 auditory relay nuclei in pons https://purl.brain-bican.org/ontology/dhbao/DHBA_12471 raphe pontis nucleus https://purl.brain-bican.org/ontology/dhbao/DHBA_12503 other nuclei in pontine tegmentum https://purl.brain-bican.org/ontology/dhbao/DHBA_12538 tegmentum of medulla oblongata https://purl.brain-bican.org/ontology/dhbao/DHBA_12539 efferent nuclei of cranial nerves in the medulla oblongata https://purl.brain-bican.org/ontology/dhbao/DHBA_12595 precerebellar nuclei https://purl.brain-bican.org/ontology/dhbao/DHBA_12666 rhombomere A https://purl.brain-bican.org/ontology/dhbao/DHBA_12773 pyramidal tract https://purl.brain-bican.org/ontology/dhbao/DHBA_146035012 adjoining structures of fourth ventricle https://purl.brain-bican.org/ontology/dhbao/DHBA_12827 surface structures of cerebellum https://purl.brain-bican.org/ontology/dhbao/DHBA_12837 cerebellar lobes and lobules https://purl.brain-bican.org/ontology/dhbao/DHBA_12856 surface structures of pons https://purl.brain-bican.org/ontology/dhbao/DHBA_12872 surface structures of medulla https://purl.brain-bican.org/ontology/dhbao/DHBA_146035116 surface structures of spinal cord https://purl.brain-bican.org/ontology/mbao/MBA_896 thalamus related http://purl.obolibrary.org/obo/RO_0004009 has primary input http://purl.obolibrary.org/obo/RO_0002233 has input p has primary input c if (a) p has input c and (b) the goal of process is to modify, consume, or transform c. http://purl.obolibrary.org/obo/RO_0040036 results in changes to anatomical or cellular structure http://purl.obolibrary.org/obo/RO_0000057 has participant p has anatomical participant c iff p has participant c, and c is an anatomical entity http://purl.obolibrary.org/obo/RO_0002100 has soma location http://purl.obolibrary.org/obo/RO_0002131 overlaps Relation between a neuron and a material anatomical entity that its soma is part of. http://purl.obolibrary.org/obo/RO_0002160 only in taxon http://purl.obolibrary.org/obo/RO_0002162 in taxon x only in taxon y if and only if x is in taxon y, and there is no other organism z such that y!=z a and x is in taxon z. http://purl.obolibrary.org/obo/RO_0002258 developmentally preceded by http://purl.obolibrary.org/obo/RO_0002324 developmentally related to Candidate definition: x developmentally related to y if and only if there exists some developmental process (GO:0032502) p such that x and y both participates in p, and x is the output of p and y is the input of p http://purl.obolibrary.org/obo/RO_0002234 has output http://purl.obolibrary.org/obo/RO_0000057 has participant p has output c iff c is a participant in p, c is present at the end of p, and c is not present in the same state at the beginning of p. http://purl.obolibrary.org/obo/RO_0002162 in taxon http://purl.obolibrary.org/obo/RO_0002320 evolutionarily related to x is in taxon y if an only if y is an organism, and the relationship between x and y is one of: part of (reflexive), developmentally preceded by, derives from, secreted by, expressed. http://purl.obolibrary.org/obo/RO_0002286 developmentally succeeded by http://purl.obolibrary.org/obo/RO_0002384 has developmental potential involving Inverse of developmentally preceded by http://purl.obolibrary.org/obo/RO_0002371 attached to http://purl.obolibrary.org/obo/RO_0002177 attached to part of a is attached to b if and only if a and b are discrete objects or object parts, and there are physical connections between a and b such that a force pulling a will move b, or a force pulling b will move a http://purl.obolibrary.org/obo/RO_0002384 has developmental potential involving http://purl.obolibrary.org/obo/RO_0002324 developmentally related to x has developmental potential involving y iff x is capable of a developmental process with output y. y may be the successor of x, or may be a different structure in the vicinity (as for example in the case of developmental induction). http://purl.obolibrary.org/obo/RO_0002388 has potential to directly develop into http://purl.obolibrary.org/obo/RO_0002387 has potential to develop into x has potential to directly develop into y iff x directly develops into y or x is capable of directly developing into y http://purl.obolibrary.org/obo/RO_0002178 supplies http://purl.obolibrary.org/obo/RO_0002170 connected to Relation between an arterial structure and another structure, where the arterial structure acts as a conduit channeling fluid, substance or energy. http://purl.obolibrary.org/obo/RO_0002372 has muscle origin http://purl.obolibrary.org/obo/RO_0002567 biomechanically related to m has_muscle_origin s iff m is attached_to s, and it is the case that when m contracts, s does not move. The site of the origin tends to be more proximal and have greater mass than what the other end attaches to. http://purl.obolibrary.org/obo/RO_0002380 branching part of http://purl.obolibrary.org/obo/RO_0002375 in branching relationship with x is a branching part of y if and only if x is part of y and x is connected directly or indirectly to the main stem of y http://purl.obolibrary.org/obo/RO_0002568 has muscle antagonist http://purl.obolibrary.org/obo/RO_0002567 biomechanically related to m1 has_muscle_antagonist m2 iff m1 has_muscle_insertion s, m2 has_muscle_insection s, m1 acts in opposition to m2, and m2 is responsible for returning the structure to its initial position. http://purl.obolibrary.org/obo/RO_0002569 has branching part http://purl.obolibrary.org/obo/RO_0002375 in branching relationship with inverse of branching part of http://purl.obolibrary.org/obo/RO_0002571 lumen of http://purl.obolibrary.org/obo/BFO_0000050 part of x lumen_of y iff x is the space or substance that is part of y and does not cross any of the inner membranes or boundaries of y that is maximal with respect to the volume of the convex hull. http://purl.obolibrary.org/obo/uberon/core#anteriorly_connected_to anteriorly connected to http://purl.obolibrary.org/obo/RO_0002170 connected to x anteriorly_connected_to y iff the anterior part of x is connected to y. i.e. x connected_to y and x posterior_to y. http://purl.obolibrary.org/obo/uberon/core#distally_connected_to distally connected to http://purl.obolibrary.org/obo/RO_0002170 connected to x distally_connected_to y iff the distal part of x is connected to y. i.e. x connected_to y and x proximal_to y. http://purl.obolibrary.org/obo/uberon/core#posteriorly_connected_to posteriorly connected to http://purl.obolibrary.org/obo/RO_0002170 connected to x posteriorly_connected_to y iff the posterior part of x is connected to y. i.e. x connected_to y and x anterior_to y. http://purl.obolibrary.org/obo/uberon/core#proximally_connected_to proximally connected to http://purl.obolibrary.org/obo/RO_0002170 connected to x proximally_connected_to y iff the proximal part of x is connected to y. i.e. x connected_to y and x distal_to y. http://purl.obolibrary.org/obo/RO_0004007 has primary input or output http://purl.obolibrary.org/obo/RO_0000057 has participant p 'has primary input ot output' c iff either (a) p 'has primary input' c or (b) p 'has primary output' c. http://purl.obolibrary.org/obo/RO_0004008 has primary output http://purl.obolibrary.org/obo/RO_0004007 has primary input or output p has primary output c if (a) p has output c and (b) the goal of process is to modify, produce, or transform c. http://purl.obolibrary.org/obo/BFO_0000063 precedes http://purl.obolibrary.org/obo/RO_0002222 temporally related to x precedes y if and only if the time point at which x ends is before or equivalent to the time point at which y starts. Formally: x precedes y iff ω(x) <= α(y), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point. http://purl.obolibrary.org/obo/RO_0000052 characteristic of http://purl.obolibrary.org/obo/RO_0002314 characteristic of part of a relation between a specifically dependent continuant (the characteristic) and any other entity (the bearer), in which the characteristic depends on the bearer for its existence. http://purl.obolibrary.org/obo/RO_0000080 quality of http://purl.obolibrary.org/obo/RO_0000052 characteristic of a relation between a quality and an independent continuant (the bearer), in which the quality specifically depends on the bearer for its existence http://purl.obolibrary.org/obo/RO_0000086 has quality http://purl.obolibrary.org/obo/RO_0000053 has characteristic a relation between an independent continuant (the bearer) and a quality, in which the quality specifically depends on the bearer for its existence http://purl.obolibrary.org/obo/RO_0002000 2D boundary of http://purl.obolibrary.org/obo/RO_0002323 mereotopologically related to a relation between a 2D immaterial entity (the boundary) and a material entity, in which the boundary delimits the material entity http://purl.obolibrary.org/obo/RO_0002002 has 2D boundary http://purl.obolibrary.org/obo/RO_0002323 mereotopologically related to a relation between a material entity and a 2D immaterial entity (the boundary), in which the boundary delimits the material entity http://purl.obolibrary.org/obo/RO_0002219 surrounded by http://purl.obolibrary.org/obo/RO_0002220 adjacent to x surrounded_by y if and only if (1) x is adjacent to y and for every region r that is adjacent to x, r overlaps y (2) the shared boundary between x and y occupies the majority of the outermost boundary of x http://purl.obolibrary.org/obo/RO_0002220 adjacent to http://purl.obolibrary.org/obo/RO_0002163 spatially disjoint from x adjacent to y if and only if x and y share a boundary. http://purl.obolibrary.org/obo/RO_0002223 starts http://purl.obolibrary.org/obo/BFO_0000050 part of inverse of starts with http://purl.obolibrary.org/obo/RO_0002350 member of http://purl.obolibrary.org/obo/BFO_0000050 part of is member of is a mereological relation between a item and a collection. http://purl.obolibrary.org/obo/RO_0002351 has member http://purl.obolibrary.org/obo/BFO_0000051 has part has member is a mereological relation between a collection and an item. http://purl.obolibrary.org/obo/RO_0002202 develops from http://purl.obolibrary.org/obo/RO_0002258 developmentally preceded by x develops from y if and only if either (a) x directly develops from y or (b) there exists some z such that x directly develops from z and z develops from y http://purl.obolibrary.org/obo/BFO_0000051 has part http://purl.obolibrary.org/obo/RO_0002131 overlaps a core relation that holds between a whole and its part http://purl.obolibrary.org/obo/RO_0002176 connects http://purl.obolibrary.org/obo/RO_0002323 mereotopologically related to c connects a if and only if there exist some b such that a and b are similar parts of the same system, and c connects b, specifically, c connects a with b. When one structure connects two others it unites some aspect of the function or role they play within the system. http://purl.obolibrary.org/obo/RO_0002491 existence starts and ends during http://purl.obolibrary.org/obo/RO_0002492 existence ends during x exists during y if and only if: 1) the time point at which x begins to exist is after or equal to the time point at which y begins and 2) the time point at which x ceases to exist is before or equal to the point at which y ends. Formally: x existence starts and ends during y iff α(x) >= α(y) & α(x) <= ω(y) & ω(x) <= ω(y) & ω(x) >= α(y) http://purl.obolibrary.org/obo/RO_0002404 causally downstream of http://purl.obolibrary.org/obo/RO_0002427 causally downstream of or within inverse of upstream of http://purl.obolibrary.org/obo/RO_0002412 immediately causally upstream of http://purl.obolibrary.org/obo/RO_0002411 causally upstream of p is immediately causally upstream of q iff p is causally upstream of q, and the end of p is coincident with the beginning of q. http://purl.obolibrary.org/obo/RO_0002490 existence overlaps http://purl.obolibrary.org/obo/RO_0002487 relation between physical entity and a process or stage x existence overlaps y if and only if either (a) the start of x is part of y or (b) the end of x is part of y. Formally: x existence starts and ends during y iff (α(x) >= α(y) & α(x) <= ω(y)) OR (ω(x) <= ω(y) & ω(x) >= α(y)) http://purl.obolibrary.org/obo/RO_0002252 connecting branch of http://purl.obolibrary.org/obo/RO_0002375 in branching relationship with b connecting-branch-of s iff b is connected to s, and there exists some tree-like structure t such that the mereological sum of b plus s is either the same as t or a branching-part-of t. http://purl.obolibrary.org/obo/RO_0002253 has connecting branch http://purl.obolibrary.org/obo/RO_0002375 in branching relationship with inverse of connecting branch of http://purl.obolibrary.org/obo/RO_0002263 acts upstream of http://purl.obolibrary.org/obo/RO_0002264 acts upstream of or within c acts upstream of p if and only if c enables some f that is involved in p' and p' occurs chronologically before p, is not part of p, and affects the execution of p. c is a material entity and f, p, p' are processes. http://purl.obolibrary.org/obo/RO_0002304 causally upstream of, positive effect http://purl.obolibrary.org/obo/RO_0004047 causally upstream of or within, positive effect p is causally upstream of, positive effect q iff p is casually upstream of q, and the execution of p is required for the execution of q. http://purl.obolibrary.org/obo/RO_0002305 causally upstream of, negative effect http://purl.obolibrary.org/obo/RO_0004046 causally upstream of or within, negative effect p is causally upstream of, negative effect q iff p is casually upstream of q, and the execution of p decreases the execution of q. http://purl.obolibrary.org/obo/RO_0020337 has constituent monomer http://purl.obolibrary.org/obo/RO_0002180 has component A relation that holds between a polymer and its constituent monomers. P has_constituent_monomer 'm' if and only if P has_component multiple instances of 'm' and each instance of 'm' is covalently attached to another instance of 'm'. http://purl.obolibrary.org/obo/RO_0002131 overlaps http://purl.obolibrary.org/obo/RO_0002323 mereotopologically related to x overlaps y if and only if there exists some z such that x has part z and z part of y http://purl.obolibrary.org/obo/RO_0002150 continuous with http://purl.obolibrary.org/obo/RO_0002323 mereotopologically related to X continuous_with Y if and only if X and Y share a fiat boundary. http://purl.obolibrary.org/obo/RO_0002254 has developmental contribution from http://purl.obolibrary.org/obo/RO_0002258 developmentally preceded by x has developmental contribution from y iff x has some part z such that z develops from y http://purl.obolibrary.org/obo/RO_0002496 existence starts during or after http://purl.obolibrary.org/obo/RO_0002487 relation between physical entity and a process or stage x existence starts during or after y if and only if the time point at which x starts is after or equivalent to the time point at which y starts. Formally: x existence starts during or after y iff α (x) >= α (y). http://purl.obolibrary.org/obo/RO_0002497 existence ends during or before http://purl.obolibrary.org/obo/RO_0002487 relation between physical entity and a process or stage x existence ends during or before y if and only if the time point at which x ends is before or equivalent to the time point at which y ends. http://purl.obolibrary.org/obo/RO_0012000 has small molecule regulator http://purl.obolibrary.org/obo/RO_0000057 has participant a relation between a process and a continuant, in which the process is regulated by the small molecule continuant http://purl.obolibrary.org/obo/RO_0012001 has small molecule activator http://purl.obolibrary.org/obo/RO_0012000 has small molecule regulator a relation between a process and a continuant, in which the process is activated by the small molecule continuant http://purl.obolibrary.org/obo/RO_0012003 acts on population of http://purl.obolibrary.org/obo/RO_0000057 has participant p acts on population of c iff c' is a collection, has members of type c, and p has participant c http://purl.obolibrary.org/obo/RO_0012004 is small molecule regulator of http://purl.obolibrary.org/obo/RO_0002596 capable of regulating a relation between a continuant and a process, in which the continuant is a small molecule that regulates the process http://purl.obolibrary.org/obo/RO_0012005 is small molecule activator of http://purl.obolibrary.org/obo/RO_0002598 capable of positively regulating a relation between a continuant and a process, in which the continuant is a small molecule that activates the process http://purl.obolibrary.org/obo/RO_0013001 has synaptic IO in region http://purl.obolibrary.org/obo/RO_0002130 has synaptic terminal in A relationship between a neuron and a region, where the neuron has a functionally relevant number of input and/or output synapses in that region. http://purl.obolibrary.org/obo/BFO_0000062 preceded by http://purl.obolibrary.org/obo/RO_0002086 ends after x is preceded by y if and only if the time point at which y ends is before or equivalent to the time point at which x starts. Formally: x preceded by y iff ω(y) <= α(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point. http://purl.obolibrary.org/obo/RO_0002090 immediately precedes http://purl.obolibrary.org/obo/BFO_0000063 precedes http://purl.obolibrary.org/obo/GOREL_0002004 results_in_fission_of http://purl.obolibrary.org/obo/RO_0000057 has participant http://purl.obolibrary.org/obo/RO_0002087 immediately preceded by http://purl.obolibrary.org/obo/BFO_0000062 preceded by http://purl.obolibrary.org/obo/RO_0002081 before or simultaneous with http://purl.obolibrary.org/obo/RO_0002222 temporally related to http://purl.obolibrary.org/obo/RO_0002086 ends after http://purl.obolibrary.org/obo/RO_0002222 temporally related to http://purl.obolibrary.org/obo/uberon/core#layer_part_of layer part of http://purl.obolibrary.org/obo/BFO_0000050 part of http://purl.obolibrary.org/obo/uberon/core#trunk_part_of trunk_part_of http://purl.obolibrary.org/obo/BFO_0000050 part of http://purl.obolibrary.org/obo/uberon/core#filtered_through filtered through Relationship between a fluid and a material entity, where the fluid is the output of a realization of a filtration role that inheres in the material entity. http://purl.obolibrary.org/obo/RO_0002320 evolutionarily related to A relationship that holds via some environmental process http://purl.obolibrary.org/obo/RO_0002324 developmentally related to A relationship that holds between entities participating in some developmental process (GO:0032502) http://purl.obolibrary.org/obo/uberon/core#indirectly_supplies indirectly_supplies a indirectly_supplies s iff a has a branch and the branch supplies or indirectly supplies s. http://purl.obolibrary.org/obo/uberon/core#site_of site_of c site_of p if c is the bearer of a disposition that is realized by a process that has p as part. http://purl.obolibrary.org/obo/RO_0015004 has characterizing marker set A relation that applies between a cell type and a set of markers that can be used to uniquely identify that cell type. http://purl.obolibrary.org/obo/BFO_0000067 contains process [copied from inverse property 'occurs in'] b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t http://purl.obolibrary.org/obo/RO_0000053 has characteristic Inverse of characteristic_of http://purl.obolibrary.org/obo/RO_0000056 participates in a relation between a continuant and a process, in which the continuant is somehow involved in the process http://purl.obolibrary.org/obo/RO_0000057 has participant a relation between a process and a continuant, in which the continuant is somehow involved in the process http://purl.obolibrary.org/obo/RO_0001000 derives from a relation between two distinct material entities, the new entity and the old entity, in which the new entity begins to exist when the old entity ceases to exist, and the new entity inherits the significant portion of the matter of the old entity http://purl.obolibrary.org/obo/RO_0001001 derives into a relation between two distinct material entities, the old entity and the new entity, in which the new entity begins to exist when the old entity ceases to exist, and the new entity inherits the significant portion of the matter of the old entity http://purl.obolibrary.org/obo/RO_0001015 location of a relation between two independent continuants, the location and the target, in which the target is entirely within the location http://purl.obolibrary.org/obo/RO_0017001 device utilizes material X device utilizes material Y means X and Y are material entities, and X is capable of some process P that has input Y. http://purl.obolibrary.org/obo/RO_0001025 located in a relation between two independent continuants, the target and the location, in which the target is entirely within the location http://purl.obolibrary.org/obo/RO_0003000 produces a produces b if some process that occurs_in a has_output b, where a and b are material entities. Examples: hybridoma cell line produces monoclonal antibody reagent; chondroblast produces avascular GAG-rich matrix. http://purl.obolibrary.org/obo/RO_0003001 produced by a produced_by b iff some process that occurs_in b has_output a. http://purl.obolibrary.org/obo/RO_0015001 has exemplar data A relation between a material entity and some data in which the data is taken as exemplifying the material entity. http://purl.obolibrary.org/obo/STATO_0000101 has numerator the relationship between a fraction and the number above the line http://purl.obolibrary.org/obo/STATO_0000259 has denominator the relationship between a fraction and the number below the line (or divisor) http://purl.obolibrary.org/obo/uberon/core#channels_from channels_from http://purl.obolibrary.org/obo/uberon/core#channels_into channels_into http://purl.obolibrary.org/obo/uberon/core#transitively_anteriorly_connected_to transitively anteriorly connected to http://purl.obolibrary.org/obo/uberon/core#transitively_distally_connected_to transitively distally connected to http://purl.obolibrary.org/obo/uberon/core#transitively_proximally_connected_to transitively proximally connected to http://purl.obolibrary.org/obo/RO_0002487 relation between physical entity and a process or stage http://purl.obolibrary.org/obo/CL_4030045 lacks_part http://purl.obolibrary.org/obo/RO_0002411 causally upstream of http://purl.obolibrary.org/obo/RO_0002418 causally upstream of or within p is causally upstream of q iff p is causally related to q, the end of p precedes the end of q, and p is not an occurrent part of q. http://purl.obolibrary.org/obo/BFO_0000050 part of http://purl.obolibrary.org/obo/RO_0002131 overlaps a core relation that holds between a part and its whole http://purl.obolibrary.org/obo/RO_0002211 regulates http://purl.obolibrary.org/obo/RO_0002411 causally upstream of p regulates q iff p is causally upstream of q, the execution of p is not constant and varies according to specific conditions, and p influences the rate or magnitude of execution of q due to an effect either on some enabler of q or some enabler of a part of q. http://purl.obolibrary.org/obo/RO_0002212 negatively regulates http://purl.obolibrary.org/obo/RO_0002211 regulates p negatively regulates q iff p regulates q, and p decreases the rate or magnitude of execution of q. http://purl.obolibrary.org/obo/RO_0002213 positively regulates http://purl.obolibrary.org/obo/RO_0002211 regulates p positively regulates q iff p regulates q, and p increases the rate or magnitude of execution of q. http://purl.obolibrary.org/obo/RO_0002180 has component http://purl.obolibrary.org/obo/BFO_0000051 has part w 'has component' p if w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type. http://purl.obolibrary.org/obo/RO_0002163 spatially disjoint from http://purl.obolibrary.org/obo/RO_0002323 mereotopologically related to A is spatially_disjoint_from B if and only if they have no parts in common http://purl.obolibrary.org/obo/RO_0002233 has input http://purl.obolibrary.org/obo/RO_0000057 has participant p has input c iff: p is a process, c is a material entity, c is a participant in p, c is present at the start of p, and the state of c is modified during p. http://purl.obolibrary.org/obo/RO_0002314 characteristic of part of http://purl.obolibrary.org/obo/RO_0002502 depends on q characteristic of part of w if and only if there exists some p such that q inheres in p and p part of w. http://purl.obolibrary.org/obo/RO_0002352 input of http://purl.obolibrary.org/obo/RO_0002328 functionally related to inverse of has input http://purl.obolibrary.org/obo/RO_0002353 output of http://purl.obolibrary.org/obo/RO_0002328 functionally related to inverse of has output http://purl.obolibrary.org/obo/RO_0002473 composed primarily of http://purl.obolibrary.org/obo/BFO_0000051 has part x composed_primarily_of y if and only if more than half of the mass of x is made from y or units of the same type as y. http://purl.obolibrary.org/obo/RO_0002104 has plasma membrane part http://purl.obolibrary.org/obo/BFO_0000051 has part Holds between a cell c and a protein complex or protein p if and only if that cell has as part a plasma_membrane[GO:0005886], and that plasma membrane has p as part. http://purl.obolibrary.org/obo/RO_0002203 develops into http://purl.obolibrary.org/obo/RO_0002387 has potential to develop into inverse of develops from http://purl.obolibrary.org/obo/RO_0002215 capable of http://purl.obolibrary.org/obo/RO_0002216 capable of part of A relation between a material entity (such as a cell) and a process, in which the material entity has the ability to carry out the process. http://purl.obolibrary.org/obo/RO_0002387 has potential to develop into http://purl.obolibrary.org/obo/RO_0002384 has developmental potential involving x has the potential to develop into y iff x develops into y or if x is capable of developing into y http://purl.obolibrary.org/obo/RO_0002021 occurs across http://purl.obolibrary.org/obo/RO_0002479 has part that occurs in A relationship between a process and a barrier, where the process occurs in a region spanning the barrier. For cellular processes the barrier is typically a membrane. Examples include transport across a membrane and membrane depolarization. http://purl.obolibrary.org/obo/RO_0015007 increased in magnitude relative to http://purl.obolibrary.org/obo/RO_0015006 different in magnitude relative to q1 increased_in_magnitude_relative_to q2 if and only if magnitude(q1) > magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale. http://purl.obolibrary.org/obo/RO_0015008 decreased in magnitude relative to http://purl.obolibrary.org/obo/RO_0015006 different in magnitude relative to q1 decreased_in_magnitude_relative_to q2 if and only if magnitude(q1) < magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale. http://purl.obolibrary.org/obo/RO_0002007 bounding layer of http://purl.obolibrary.org/obo/BFO_0000050 part of X outer_layer_of Y iff: . X :continuant that bearer_of some PATO:laminar . X part_of Y . exists Z :surface . X has_boundary Z . Z boundary_of Y has_boundary: http://purl.obolibrary.org/obo/RO_0002002 boundary_of: http://purl.obolibrary.org/obo/RO_0002000 http://purl.obolibrary.org/obo/RO_0002170 connected to http://purl.obolibrary.org/obo/RO_0002323 mereotopologically related to a is connected to b if and only if a and b are discrete structure, and there exists some connecting structure c, such that c connects a and b http://purl.obolibrary.org/obo/RO_0002177 attached to part of http://purl.obolibrary.org/obo/RO_0002567 biomechanically related to a is attached to part of b if a is attached to b, or a is attached to some p, where p is part of b. http://purl.obolibrary.org/obo/RO_0002179 drains http://purl.obolibrary.org/obo/RO_0002170 connected to Relation between an collecting structure and another structure, where the collecting structure acts as a conduit channeling fluid, substance or energy away from the other structure. http://purl.obolibrary.org/obo/RO_0002264 acts upstream of or within http://purl.obolibrary.org/obo/RO_0002500 causal agent in process c acts upstream of or within p if c is enables f, and f is causally upstream of or within p. c is a material entity and p is an process. http://purl.obolibrary.org/obo/RO_0002375 in branching relationship with http://purl.obolibrary.org/obo/RO_0002323 mereotopologically related to A relationship that holds between two material entities in a system of connected structures, where the branching relationship holds based on properties of the connecting network. http://purl.obolibrary.org/obo/RO_0002376 tributary of http://purl.obolibrary.org/obo/RO_0002375 in branching relationship with x tributary_of y if and only if x a channel for the flow of a substance into y, where y is larger than x. If x and y are hydrographic features, then y is the main stem of a river, or a lake or bay, but not the sea or ocean. If x and y are anatomical, then y is a vein. http://purl.obolibrary.org/obo/RO_0002431 involved in or involved in regulation of http://purl.obolibrary.org/obo/RO_0002500 causal agent in process c involved in or regulates p if and only if either (i) c is involved in p or (ii) c is involved in regulation of p http://purl.obolibrary.org/obo/RO_0002567 biomechanically related to http://purl.obolibrary.org/obo/RO_0002328 functionally related to A relation that holds between elements of a musculoskeletal system or its analogs. http://purl.obolibrary.org/obo/RO_0002373 has muscle insertion http://purl.obolibrary.org/obo/RO_0002567 biomechanically related to m has_muscle_insertion s iff m is attaches_to s, and it is the case that when m contracts, s moves. Insertions are usually connections of muscle via tendon to bone. http://purl.obolibrary.org/obo/RO_0002433 contributes to morphology of http://purl.obolibrary.org/obo/RO_0002131 overlaps p contributes to morphology of w if and only if a change in the morphology of p entails a change in the morphology of w. Examples: every skull contributes to morphology of the head which it is a part of. Counter-example: nuclei do not generally contribute to the morphology of the cell they are part of, as they are buffered by cytoplasm. http://purl.obolibrary.org/obo/RO_0002488 existence starts during http://purl.obolibrary.org/obo/RO_0002496 existence starts during or after x existence starts during y if and only if the time point at which x starts is after or equivalent to the time point at which y starts and before or equivalent to the time point at which y ends. Formally: x existence starts during y iff α(x) >= α(y) & α(x) <= ω(y). http://purl.obolibrary.org/obo/RO_0002489 existence starts with http://purl.obolibrary.org/obo/RO_0002488 existence starts during x starts ends with y if and only if the time point at which x starts is equivalent to the time point at which y starts. Formally: x existence starts with y iff α(x) = α(y). http://purl.obolibrary.org/obo/RO_0002492 existence ends during http://purl.obolibrary.org/obo/RO_0002497 existence ends during or before x existence ends during y if and only if the time point at which x ends is before or equivalent to the time point at which y ends and after or equivalent to the point at which y starts. Formally: x existence ends during y iff ω(x) <= ω(y) and ω(x) >= α(y). http://purl.obolibrary.org/obo/RO_0002493 existence ends with http://purl.obolibrary.org/obo/RO_0002492 existence ends during x existence ends with y if and only if the time point at which x ends is equivalent to the time point at which y ends. Formally: x existence ends with y iff ω(x) = ω(y). http://purl.obolibrary.org/obo/RO_0002494 transformation of http://purl.obolibrary.org/obo/RO_0002202 develops from x transformation of y if x is the immediate transformation of y, or is linked to y through a chain of transformation relationships http://purl.obolibrary.org/obo/RO_0002495 immediate transformation of http://purl.obolibrary.org/obo/RO_0002207 directly develops from x immediate transformation of y iff x immediately succeeds y temporally at a time boundary t, and all of the matter present in x at t is present in y at t, and all the matter in y at t is present in x at t http://purl.obolibrary.org/obo/RO_0002551 has skeleton http://purl.obolibrary.org/obo/BFO_0000051 has part A relation between a segment or subdivision of an organism and the maximal subdivision of material entities that provides structural support for that segment or subdivision. http://purl.obolibrary.org/obo/RO_0002572 luminal space of http://purl.obolibrary.org/obo/RO_0002571 lumen of s is luminal space of x iff s is lumen_of x and s is an immaterial entity http://purl.obolibrary.org/obo/RO_0002576 skeleton of http://purl.obolibrary.org/obo/BFO_0000050 part of inverse of has skeleton http://purl.obolibrary.org/obo/uberon/core#extends_fibers_into extends_fibers_into http://purl.obolibrary.org/obo/RO_0002170 connected to X extends_fibers into Y iff there exists some neuron (N) and N has_soma_location X and N 'has synaptic IO in region' some Y http://purl.obolibrary.org/obo/RO_0020101 vessel supplies blood to http://purl.obolibrary.org/obo/RO_0002178 supplies x vessel supplies blood to y if and only if x is a vessel that supplies blood directly or indirectly to an anatomical structure y. http://purl.obolibrary.org/obo/RO_0020102 vessel drains blood from http://purl.obolibrary.org/obo/RO_0002179 drains x vessel drains blood from y if and only if x is a vessel that drains blood directly or indirectly from an anatomical structure y. http://purl.obolibrary.org/obo/RO_0002101 fasciculates with http://purl.obolibrary.org/obo/RO_0002131 overlaps relationship between a neuron and a neuron projection bundle (e.g.- tract or nerve bundle) that one or more of its projections travels through. http://purl.obolibrary.org/obo/RO_0002103 synapsed by http://purl.obolibrary.org/obo/RO_0002485 receives input from Relation between an anatomical structure (including cells) and a neuron that chemically synapses to it. http://purl.obolibrary.org/obo/RO_0002110 has postsynaptic terminal in http://purl.obolibrary.org/obo/RO_0002130 has synaptic terminal in Relation between a neuron and some structure (e.g.- a brain region) in which it receives (chemical) synaptic input. http://purl.obolibrary.org/obo/RO_0002113 has presynaptic terminal in http://purl.obolibrary.org/obo/RO_0002130 has synaptic terminal in Relation between a neuron and some structure (e.g.- a brain region) in which it receives (chemical) synaptic input. http://purl.obolibrary.org/obo/RO_0002120 synapsed to http://purl.obolibrary.org/obo/RO_0002486 sends output to Relation between a neuron and an anatomical structure (including cells) that it chemically synapses to. http://purl.obolibrary.org/obo/RO_0002130 has synaptic terminal in http://purl.obolibrary.org/obo/RO_0002131 overlaps A general relation between a neuron and some structure in which it either chemically synapses to some target or in which it receives (chemical) synaptic input. http://purl.obolibrary.org/obo/RO_0002216 capable of part of http://purl.obolibrary.org/obo/RO_0002500 causal agent in process c stands in this relationship to p if and only if there exists some p' such that c is capable_of p', and p' is part_of p. http://purl.obolibrary.org/obo/RO_0002255 developmentally contributes to http://purl.obolibrary.org/obo/RO_0002385 has potential to developmentally contribute to inverse of has developmental contribution from http://purl.obolibrary.org/obo/RO_0002329 part of structure that is capable of http://purl.obolibrary.org/obo/RO_0002328 functionally related to this relation holds between c and p when c is part of some c', and c' is capable of p. http://purl.obolibrary.org/obo/RO_0002334 regulated by http://purl.obolibrary.org/obo/RO_0002427 causally downstream of or within inverse of regulates http://purl.obolibrary.org/obo/RO_0002335 negatively regulated by http://purl.obolibrary.org/obo/RO_0002334 regulated by inverse of negatively regulates http://purl.obolibrary.org/obo/RO_0002336 positively regulated by http://purl.obolibrary.org/obo/RO_0002334 regulated by inverse of positively regulates http://purl.obolibrary.org/obo/RO_0002379 spatially coextensive with http://purl.obolibrary.org/obo/RO_0002131 overlaps x spatially_coextensive_with y if and inly if x and y have the same location http://purl.obolibrary.org/obo/RO_0002385 has potential to developmentally contribute to http://purl.obolibrary.org/obo/RO_0002384 has developmental potential involving x has potential to developmentrally contribute to y iff x developmentally contributes to y or x is capable of developmentally contributing to y http://purl.obolibrary.org/obo/RO_0002418 causally upstream of or within http://purl.obolibrary.org/obo/RO_0002501 causal relation between processes p is 'causally upstream or within' q iff p is causally related to q, and the end of p precedes, or is coincident with, the end of q. http://purl.obolibrary.org/obo/RO_0002427 causally downstream of or within http://purl.obolibrary.org/obo/RO_0002501 causal relation between processes inverse of causally upstream of or within http://purl.obolibrary.org/obo/RO_0002500 causal agent in process http://purl.obolibrary.org/obo/RO_0002595 causal relation between material entity and a process A relationship between a material entity and a process where the material entity has some causal role that influences the process http://purl.obolibrary.org/obo/RO_0002501 causal relation between processes http://purl.obolibrary.org/obo/RO_0002410 causally related to p is causally related to q if and only if p or any part of p and q or any part of q are linked by a chain of events where each event pair is one where the execution of p influences the execution of q. p may be upstream, downstream, part of, or a container of q. http://purl.obolibrary.org/obo/RO_0002584 has part structure that is capable of http://purl.obolibrary.org/obo/RO_0002595 causal relation between material entity and a process s 'has part structure that is capable of' p if and only if there exists some part x such that s 'has part' x and x 'capable of' p http://purl.obolibrary.org/obo/RO_0002595 causal relation between material entity and a process http://purl.obolibrary.org/obo/RO_0002410 causally related to A relationship that holds between a material entity and a process in which causality is involved, with either the material entity or some part of the material entity exerting some influence over the process, or the process influencing some aspect of the material entity. http://purl.obolibrary.org/obo/RO_0002596 capable of regulating http://purl.obolibrary.org/obo/RO_0002500 causal agent in process Holds between c and p if and only if c is capable of some activity a, and a regulates p. http://purl.obolibrary.org/obo/RO_0002597 capable of negatively regulating http://purl.obolibrary.org/obo/RO_0002596 capable of regulating Holds between c and p if and only if c is capable of some activity a, and a negatively regulates p. http://purl.obolibrary.org/obo/RO_0002598 capable of positively regulating http://purl.obolibrary.org/obo/RO_0002596 capable of regulating Holds between c and p if and only if c is capable of some activity a, and a positively regulates p. http://purl.obolibrary.org/obo/RO_0002608 process has causal agent http://purl.obolibrary.org/obo/RO_0002410 causally related to Inverse of 'causal agent in process' http://purl.obolibrary.org/obo/RO_0002082 simultaneous with http://purl.obolibrary.org/obo/RO_0002081 before or simultaneous with x simultaneous with y iff ω(x) = ω(y) and ω(α ) = ω(α), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point and '=' indicates the same instance in time. http://purl.obolibrary.org/obo/RO_0002102 axon synapses in http://purl.obolibrary.org/obo/RO_0002113 has presynaptic terminal in Relation between a neuron and some structure its axon forms (chemical) synapses in. http://purl.obolibrary.org/obo/RO_0002132 has fasciculating neuron projection http://purl.obolibrary.org/obo/RO_0002131 overlaps The relation between a neuron projection bundle and a neuron projection that is fasciculated with it. http://purl.obolibrary.org/obo/RO_0002158 shares ancestor with http://purl.obolibrary.org/obo/RO_0002320 evolutionarily related to two individual entities d1 and d2 stand in a shares_ancestor_with relation if and only if there exists some a such that d1 derived_by_descent_from a and d2 derived_by_descent_from a. http://purl.obolibrary.org/obo/RO_0002206 expressed in http://purl.obolibrary.org/obo/RO_0002330 genomically related to x expressed in y if and only if there is a gene expression process (GO:0010467) that occurs in y, and one of the following holds: (i) x is a gene, and x is transcribed into a transcript as part of the gene expression process (ii) x is a transcript, and the transcription of x is part of the gene expression process (iii) x is a mature gene product such as a protein, and x was translated or otherwise processes from a transcript that was transcribed as part of this gene expression process http://purl.obolibrary.org/obo/RO_0002207 directly develops from http://purl.obolibrary.org/obo/RO_0002202 develops from Candidate definition: x directly_develops from y if and only if there exists some developmental process (GO:0032502) p such that x and y both participate in p, and x is the output of p and y is the input of p, and a substantial portion of the matter of x comes from y, and the start of x is coincident with or after the end of y. http://purl.obolibrary.org/obo/RO_0002210 directly develops into http://purl.obolibrary.org/obo/RO_0002203 develops into inverse of directly develops from http://purl.obolibrary.org/obo/RO_0002221 surrounds http://purl.obolibrary.org/obo/RO_0002220 adjacent to inverse of surrounded by http://purl.obolibrary.org/obo/RO_0002224 starts with http://purl.obolibrary.org/obo/RO_0002222 temporally related to x starts with y if and only if x has part y and the time point at which x starts is equivalent to the time point at which y starts. Formally: α(y) = α(x) ∧ ω(y) < ω(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point. http://purl.obolibrary.org/obo/RO_0002225 develops from part of http://purl.obolibrary.org/obo/RO_0002202 develops from x develops from part of y if and only if there exists some z such that x develops from z and z is part of y http://purl.obolibrary.org/obo/RO_0002226 develops in http://purl.obolibrary.org/obo/RO_0002258 developmentally preceded by x develops_in y if x is located in y whilst x is developing http://purl.obolibrary.org/obo/RO_0002229 ends http://purl.obolibrary.org/obo/BFO_0000050 part of inverse of ends with http://purl.obolibrary.org/obo/RO_0002230 ends with http://purl.obolibrary.org/obo/RO_0002222 temporally related to x ends with y if and only if x has part y and the time point at which x ends is equivalent to the time point at which y ends. Formally: α(y) > α(x) ∧ ω(y) = ω(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point. http://purl.obolibrary.org/obo/RO_0002231 has start location http://purl.obolibrary.org/obo/RO_0002479 has part that occurs in x 'has starts location' y if and only if there exists some process z such that x 'starts with' z and z 'occurs in' y http://purl.obolibrary.org/obo/RO_0002232 has end location http://purl.obolibrary.org/obo/RO_0002479 has part that occurs in x 'has end location' y if and only if there exists some process z such that x 'ends with' z and z 'occurs in' y http://purl.obolibrary.org/obo/RO_0002256 developmentally induced by http://purl.obolibrary.org/obo/RO_0002258 developmentally preceded by t1 induced_by t2 if there is a process of developmental induction (GO:0031128) with t1 and t2 as interacting participants. t2 causes t1 to change its fate from a precursor material anatomical entity type T to T', where T' develops_from T http://purl.obolibrary.org/obo/RO_0002257 developmentally induces http://purl.obolibrary.org/obo/RO_0002386 has potential to developmentally induce Inverse of developmentally induced by http://purl.obolibrary.org/obo/RO_0002285 developmentally replaces http://purl.obolibrary.org/obo/RO_0002258 developmentally preceded by x developmentally replaces y if and only if there is some developmental process that causes x to move or to cease to exist, and for the site that was occupied by x to become occupied by y, where y either comes into existence in this site or moves to this site from somewhere else http://purl.obolibrary.org/obo/RO_0002292 expresses http://purl.obolibrary.org/obo/RO_0002330 genomically related to y expresses x if and only if there is a gene expression process (GO:0010467) that occurs in y, and one of the following holds: (i) x is a gene, and x is transcribed into a transcript as part of the gene expression process (ii) x is a transcript, and x was transcribed from a gene as part of the gene expression process (iii) x is a mature gene product (protein or RNA), and x was translated or otherwise processed from a transcript that was transcribed as part of the gene expression process. http://purl.obolibrary.org/obo/RO_0002295 results in developmental progression of http://purl.obolibrary.org/obo/RO_0002324 developmentally related to p results in the developmental progression of s iff p is a developmental process and s is an anatomical entity and p causes s to undergo a change in state at some point along its natural developmental cycle (this cycle starts with its formation, through the mature structure, and ends with its loss). http://purl.obolibrary.org/obo/RO_0002296 results in development of http://purl.obolibrary.org/obo/RO_0002295 results in developmental progression of p 'results in development of' c if and only if p is a developmental process and p results in the state of c changing from its initial state as a primordium or anlage through its mature state and to its final state. http://purl.obolibrary.org/obo/RO_0002298 results in morphogenesis of http://purl.obolibrary.org/obo/RO_0002295 results in developmental progression of The relationship that links an entity with the process that results in the formation and shaping of that entity over time from an immature to a mature state. http://purl.obolibrary.org/obo/RO_0002299 results in maturation of http://purl.obolibrary.org/obo/RO_0002295 results in developmental progression of The relationship that links an entity with a process that results in the progression of the entity over time that is independent of changes in it's shape and results in an end point state of that entity. http://purl.obolibrary.org/obo/RO_0015003 subcluster of http://purl.obolibrary.org/obo/BFO_0000050 part of A relation between a group and another group it is part of but does not fully constitute. http://purl.obolibrary.org/obo/RO_0015015 has high plasma membrane amount http://purl.obolibrary.org/obo/RO_0002104 has plasma membrane part A relation between a cell and molecule or complex such that every instance of the cell has a high number of instances of that molecule expressed on the cell surface. http://purl.obolibrary.org/obo/RO_0015016 has low plasma membrane amount http://purl.obolibrary.org/obo/RO_0002104 has plasma membrane part A relation between a cell and molecule or complex such that every instance of the cell has a low number of instances of that molecule expressed on the cell surface. http://purl.obolibrary.org/obo/RO_0013007 has sensory dendrite in http://purl.obolibrary.org/obo/RO_0002360 has dendrite location Relation between a sensory neuron and some structure in which it receives sensory input via a sensory dendrite. http://purl.obolibrary.org/obo/RO_0002315 results in acquisition of features of http://purl.obolibrary.org/obo/RO_0002295 results in developmental progression of The relationship that links a specified entity with the process that results in an unspecified entity acquiring the features and characteristics of the specified entity http://purl.obolibrary.org/obo/RO_0002332 regulates levels of http://purl.obolibrary.org/obo/RO_0002328 functionally related to p regulates levels of c if p regulates some amount (PATO:0000070) of c http://purl.obolibrary.org/obo/RO_0002338 has target start location http://purl.obolibrary.org/obo/RO_0002344 results in transport to from or in This relationship holds between p and l when p is a transport or localization process in which the outcome is to move some cargo c from some initial location l to some destination. http://purl.obolibrary.org/obo/RO_0002339 has target end location http://purl.obolibrary.org/obo/RO_0002344 results in transport to from or in This relationship holds between p and l when p is a transport or localization process in which the outcome is to move some cargo c from a an initial location to some destination l. http://purl.obolibrary.org/obo/RO_0002341 results in transport along http://purl.obolibrary.org/obo/RO_0002337 related via localization to Holds between p and l when p is a transportation or localization process and the outcome of this process is to move c from one location to another, and the route taken by c follows a path that is aligned_with l http://purl.obolibrary.org/obo/RO_0002342 results in transport across http://purl.obolibrary.org/obo/RO_0002344 results in transport to from or in Holds between p and m when p is a transportation or localization process and the outcome of this process is to move c from one location to another, and the route taken by c follows a path that crosses m. http://purl.obolibrary.org/obo/RO_0002386 has potential to developmentally induce http://purl.obolibrary.org/obo/RO_0002384 has developmental potential involving x has potential to developmentally induce y iff x developmentally induces y or x is capable of developmentally inducing y http://purl.obolibrary.org/obo/RO_0002413 provides input for http://purl.obolibrary.org/obo/RO_0002414 transitively provides input for p provides input for q iff p is immediately causally upstream of q, and there exists some c such that p has_output c and q has_input c. http://purl.obolibrary.org/obo/RO_0002414 transitively provides input for http://purl.obolibrary.org/obo/RO_0004047 causally upstream of or within, positive effect transitive form of directly_provides_input_for http://purl.obolibrary.org/obo/RO_0002428 involved in regulation of http://purl.obolibrary.org/obo/RO_0002431 involved in or involved in regulation of c involved in regulation of p if c is involved in some p' and p' regulates some p http://purl.obolibrary.org/obo/RO_0002565 results in movement of http://purl.obolibrary.org/obo/RO_0040036 results in changes to anatomical or cellular structure Holds between p and c when p is locomotion process and the outcome of this process is the change of location of c http://purl.obolibrary.org/obo/RO_0002570 conduit for http://purl.obolibrary.org/obo/RO_0002131 overlaps x is a conduit for y iff y overlaps through the lumen_of of x, and y has parts on either side of the lumen of x. http://purl.obolibrary.org/obo/RO_0002586 results in breakdown of http://purl.obolibrary.org/obo/RO_0002233 has input p results in breakdown of c if and only if the execution of p leads to c no longer being present at the end of p http://purl.obolibrary.org/obo/RO_0002592 results in organization of http://purl.obolibrary.org/obo/RO_0040036 results in changes to anatomical or cellular structure p results in organization of c iff p results in the assembly, arrangement of constituent parts, or disassembly of c http://purl.obolibrary.org/obo/RO_0002343 results in growth of http://purl.obolibrary.org/obo/RO_0002295 results in developmental progression of http://purl.obolibrary.org/obo/RO_0002297 results in formation of anatomical entity http://purl.obolibrary.org/obo/RO_0002295 results in developmental progression of http://purl.obolibrary.org/obo/RO_0002287 part of developmental precursor of http://purl.obolibrary.org/obo/RO_0002286 developmentally succeeded by http://purl.obolibrary.org/obo/RO_0002405 immediately causally downstream of http://purl.obolibrary.org/obo/RO_0002404 causally downstream of http://purl.obolibrary.org/obo/RO_0002006 has synaptic terminal of http://purl.obolibrary.org/obo/RO_0002131 overlaps http://purl.obolibrary.org/obo/RO_0002360 has dendrite location http://purl.obolibrary.org/obo/RO_0002131 overlaps http://purl.obolibrary.org/obo/RO_0002354 formed as result of http://purl.obolibrary.org/obo/RO_0002353 output of http://purl.obolibrary.org/obo/RO_0002485 receives input from http://purl.obolibrary.org/obo/RO_0002170 connected to http://purl.obolibrary.org/obo/RO_0002486 sends output to http://purl.obolibrary.org/obo/RO_0002170 connected to http://purl.obolibrary.org/obo/RO_0004046 causally upstream of or within, negative effect http://purl.obolibrary.org/obo/RO_0002418 causally upstream of or within http://purl.obolibrary.org/obo/RO_0004047 causally upstream of or within, positive effect http://purl.obolibrary.org/obo/RO_0002418 causally upstream of or within http://purl.obolibrary.org/obo/uberon/core#sexually_homologous_to sexually_homologous_to http://purl.obolibrary.org/obo/RO_0002158 shares ancestor with http://purl.obolibrary.org/obo/RO_0002588 results in assembly of http://purl.obolibrary.org/obo/RO_0002592 results in organization of http://purl.obolibrary.org/obo/RO_0002344 results in transport to from or in http://purl.obolibrary.org/obo/RO_0002337 related via localization to http://purl.obolibrary.org/obo/RO_0002590 results in disassembly of http://purl.obolibrary.org/obo/RO_0002592 results in organization of http://purl.obolibrary.org/obo/RO_0012008 results in fusion of http://purl.obolibrary.org/obo/RO_0002592 results in organization of http://purl.obolibrary.org/obo/RO_0015006 different in magnitude relative to q1 different_in_magnitude_relative_to q2 if and only if magnitude(q1) NOT =~ magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale. http://purl.obolibrary.org/obo/BFO_0000066 occurs in b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t http://purl.obolibrary.org/obo/RO_0002323 mereotopologically related to A mereological relationship or a topological relationship http://purl.obolibrary.org/obo/RO_0002328 functionally related to A grouping relationship for any relationship directly involving a function, or that holds because of a function of one of the related entities. http://purl.obolibrary.org/obo/cl#has_high_plasma_membrane_amount obsolete has_high_plasma_membrane_amount OBSOLETE A relation between a cell and molecule or complex such that every instance of the cell has a high number of instances of that molecule expressed on the cell surface. For the formal definition, see Masci et al (PMID:19243617). http://purl.obolibrary.org/obo/cl#has_low_plasma_membrane_amount obsolete has_low_plasma_membrane_amount OBSOLETE A relation between a cell and molecule or complex such that every instance of the cell has a low number of instances of that molecule expressed on the cell surface. For the formal definition, see Masci et al (PMID:19243617). http://purl.obolibrary.org/obo/RO_0015011 has cross section s3 has_cross_section s3 if and only if : there exists some 2d plane that intersects the bearer of s3, and the impression of s3 upon that plane has shape quality s2. http://purl.obolibrary.org/obo/RO_0020104 is neuron This property only applies to neurons http://purl.obolibrary.org/obo/RO_0020105 is anatomical entity This property only applies to anatomical entities. http://purl.obolibrary.org/obo/RO_0002330 genomically related to holds between two entities when some genome-level process such as gene expression is involved. This includes transcriptional, spliceosomal events. These relations can be used between either macromolecule entities (such as regions of nucleic acid) or between their abstract informational counterparts. http://purl.obolibrary.org/obo/RO_0002134 innervates Relation between a 'neuron projection bundle' and a region in which one or more of its component neuron projections either synapses to targets or receives synaptic input. T innervates some R Expands_to: T has_fasciculating_neuron_projection that synapse_in some R. http://purl.obolibrary.org/obo/RO_0002005 innervated by relation between an anatomical structure and a neuron projection bundle that has synaptic terminals in the structure. http://purl.obolibrary.org/obo/RO_0002410 causally related to relation that links two events, processes, states, or objects such that one event, process, state, or object (a cause) contributes to the production of another event, process, state, or object (an effect) where the cause is partly or wholly responsible for the effect, and the effect is partly or wholly dependent on the cause. http://purl.obolibrary.org/obo/RO_0002479 has part that occurs in p has part that occurs in c if and only if there exists some p1, such that p has_part p1, and p1 occurs in c. http://purl.obolibrary.org/obo/RO_0002337 related via localization to A relationship that holds via some process of localization http://purl.obolibrary.org/obo/RO_0002222 temporally related to http://purl.obolibrary.org/obo/CL_4030044 has_not_completed http://purl.obolibrary.org/obo/CL_4030046 lacks_plasma_membrane_part http://purl.obolibrary.org/obo/RO_0002502 depends on http://purl.obolibrary.org/obo/RO_0015010 has relative magnitude http://purl.obolibrary.org/obo/uberon/core#channel_for channel for http://purl.obolibrary.org/obo/uberon/core#protects protects http://purl.obolibrary.org/obo/uberon/core#subdivision_of subdivision of http://purl.obolibrary.org/obo/RO_0015002 exemplar data of http://purl.obolibrary.org/obo/GOREL_0002003 results_in_distribution_of