Term IRI	Term label	Parent term IRI	Parent term label	Alternative term	Definition
http://purl.obolibrary.org/obo/OAE_0000003	causal adverse event	http://purl.obolibrary.org/obo/OAE_0000001	adverse event	adverse effect	an adverse event which is a causal adverse event, a pathological bodily process that is induced by a medical intervention.
http://purl.obolibrary.org/obo/OAE_0000040	procedural complication AE	http://purl.obolibrary.org/obo/OAE_0000001	adverse event	procedure AE	an adverse event that shows a complication that occurs after a medical procedure such as a surgery.
http://purl.obolibrary.org/obo/OAE_0000476	immune system AE	http://purl.obolibrary.org/obo/OAE_0000001	adverse event	immune system disorder AE	an AE that occurs in immune system.
http://purl.obolibrary.org/obo/OAE_0000568	allergy AE	http://purl.obolibrary.org/obo/OAE_0000584	hypersensitivity AE	anaphylactic reaction AE	a hypersensitivity AE which results in an allergic response showing a marked increase in reactivity to an antigen upon subsequent exposure.
http://purl.obolibrary.org/obo/OAE_0000584	hypersensitivity AE	http://purl.obolibrary.org/obo/OAE_0000476	immune system AE	hypersensitivity reaction AE	Hypersensitivity AE is a immune system AE that is a set of undesirable reactions produced by the normal immune system, including allergies and autoimmunity. These reactions may be damaging, uncomfortable, or occasionally fatal.
http://purl.obolibrary.org/obo/OAE_0001750	severity of adverse event	http://purl.obolibrary.org/obo/PATO_0001236	process characteristic	AE severity	a process quality that represents the level of severity of an adverse event.
http://purl.obolibrary.org/obo/OAE_0001836	AE severity G1	http://purl.obolibrary.org/obo/OAE_0001750	severity of adverse event	AE severity Grade 1	a severity of AE that shows asymptomatic, or involves mild or minor symptoms, or is of marginal clinical relevance, or consists of clinical or diagnostic observations alone, or where intervention is not indicated, or where only non-prescription intervention is indicated.
http://purl.obolibrary.org/obo/OAE_0001837	AE severity G2	http://purl.obolibrary.org/obo/OAE_0001750	severity of adverse event	AE severity Grade 2	a severity of AE for which only minimal, local, or noninvasive intervention (e.g. packing, cautery) is indicated, or that limits instrumental activities of daily living (ADLs, e.g., shopping, laundry, transportation, or ability to conduct finances).
http://purl.obolibrary.org/obo/OAE_0001838	AE severity G3	http://purl.obolibrary.org/obo/OAE_0001750	severity of adverse event	AE severity Grade 3	a severity of AE that shows an outcome which is medically significant but not life-threatening; or for which inpatient care or prolongation of hospitalization are indicated; or that is an important medical event that does not result in hospitalization, but may jeopardize the patient or may require intervention either to prevent hospitalization, to prevent the AE from becoming life-threatening or causing death; or that is disabling; or that results in persistent or significant disability, incapacity, or limitation of self care activities of daily living (ADLs, getting in and out of bed, dressing, eating, getting around inside, bathing, or using the toilet).
http://purl.obolibrary.org/obo/OAE_0001839	AE severity G4	http://purl.obolibrary.org/obo/OAE_0001750	severity of adverse event	AE severity Grade 4	a severity of AE that has life-threatening consequences, for which urgent intervention is indicated, that puts the patient is at risk of death at the time of the event if immediate intervention is not undertaken, or that causes blindness or deafness (need to decide if unilateral or bilateral).
http://purl.obolibrary.org/obo/OAE_0001840	AE severity G5	http://purl.obolibrary.org/obo/OAE_0001750	severity of adverse event	AE severity Grade 5	a severity of AE that results in death.
http://purl.obolibrary.org/obo/OAE_0002617	medical device adverse event	http://purl.obolibrary.org/obo/OAE_0000040	procedural complication AE	device adverse event	a procedural complication AE that occurs after the usage of a medical device.
http://purl.obolibrary.org/obo/CMEO_0000002	wearable device	http://purl.obolibrary.org/obo/COB_0001300	device	health wearable	A device that is designed to be worn on, or attached to, the body of a person and that senses, records, or transmits data about the wearer's physiological, behavioral, or environmental state, continuously or intermittently.
http://purl.obolibrary.org/obo/CMEO_0000007	data mapping	http://purl.obolibrary.org/obo/COB_0000035	completely executed planned process	data standardization	A planned process that links a concept to a unique identifier in the respective domain standard (for example, linking the variable 'bp' to the blood pressure concept in SNOMED).
http://purl.obolibrary.org/obo/CMEO_0000026	concept code	http://purl.obolibrary.org/obo/IAO_0000028	symbol	Concept	A symbol (a string of characters) that is assigned to a concept within a standardized terminology or classification system (e.g., a SNOMED CT or LOINC code) in order to identify and denote that concept.
http://purl.obolibrary.org/obo/CMEO_0000064	primary outcome specification	http://purl.obolibrary.org/obo/CMEO_0000063	study outcome specification	primary endpoint specification	An outcome specification that identifies the main endpoint of a study and defines how it is measured or ascertained, including the event or variable of interest, the assessment time frame, and any criteria for determining outcome occurrence.
http://purl.obolibrary.org/obo/CMEO_0000065	secondary outcome specification	http://purl.obolibrary.org/obo/CMEO_0000063	study outcome specification	secondary endpoint specification	An outcome specification that defines an additional endpoint of a study beyond the primary outcome(s), including how it is measured or ascertained, the assessment time frame, and any criteria for determining outcome occurrence.
http://purl.obolibrary.org/obo/CMEO_0000070	medical exposure exclusion criterion	http://purl.obolibrary.org/obo/OBI_0500028	exclusion criterion	prior medical intervention exclusion criterion	An exclusion criterion that excludes a participant who has received, is receiving, or is scheduled to receive a specified medical intervention.
http://purl.obolibrary.org/obo/IAO_0000005	objective specification	http://purl.obolibrary.org/obo/IAO_0000033	directive information entity	goal specification	A directive information entity that describes an intended process endpoint. When part of a plan specification the concretization is realized in a planned process in which the bearer tries to effect the world so that the process endpoint is achieved.
http://purl.obolibrary.org/obo/IAO_0000027	data entity	http://purl.obolibrary.org/obo/IAO_0000030	information content entity	data item	An information content entity that is intended to be one or more truthful statement(s) about something (modulo, e.g., measurement precision or other systematic errors) and is constructed/acquired by a method which reliably tends to produce (approximately) truthful statements.
http://purl.obolibrary.org/obo/IAO_0000100	homogenous data collection	http://purl.obolibrary.org/obo/IAO_0001000	data collection	data set	A data item that is an aggregate of other data items of the same type that have something in common. Averages and distributions can be determined for data sets.
http://purl.obolibrary.org/obo/IAO_0000184	scatter plot	http://purl.obolibrary.org/obo/IAO_0000038	graph	scattergraph	A scatterplot is a graph which uses Cartesian coordinates to display values for two variables for a set of data. The data is displayed as a collection of points, each having the value of one variable determining the position on the horizontal axis and the value of the other variable determining the position on the vertical axis.
http://purl.obolibrary.org/obo/IAO_0000311	publication	http://purl.obolibrary.org/obo/IAO_0000310	document	published document	A document that is the output of a publishing process.
http://purl.obolibrary.org/obo/IAO_0000573	line graph	http://purl.obolibrary.org/obo/IAO_0000038	graph	line chart	A line graph is a type of graph created by connecting a series of data
points together with a line.
http://purl.obolibrary.org/obo/IAO_0000577	centrally registered identifier symbol	http://purl.obolibrary.org/obo/IAO_0000028	symbol	CRID symbol	A symbol that is part of a CRID and that is sufficient to look up a record from the CRID's registry.
http://purl.obolibrary.org/obo/IAO_0000578	centrally registered identifier	http://purl.obolibrary.org/obo/IAO_0020000	identifier	CRID	An information content entity that consists of a CRID symbol and additional information about the CRID registry to which it belongs.
http://purl.obolibrary.org/obo/IAO_0000579	centrally registered identifier registry	http://purl.obolibrary.org/obo/IAO_0020020	code set	CRID registry	A code set of CRID records, each consisting of a CRID symbol and additional information which was recorded in the code set through an assigning a centrally registered identifier process.
http://purl.obolibrary.org/obo/OBI_0000014	regulator role	http://purl.obolibrary.org/obo/OBI_0000017	regulatory role	regulator	a regulatory role involved with making and/or enforcing relevant legislation and governmental orders
http://purl.obolibrary.org/obo/OBI_0000018	material supplier role	http://purl.obolibrary.org/obo/OBI_0000947	service provider role	material provider role	a role realized through the process of supplying materials such as animal subjects, reagents or other materials used in an investigation.
http://purl.obolibrary.org/obo/OBI_0000023	classified data set	http://purl.obolibrary.org/obo/IAO_0000100	homogenous data collection	data set with assigned class labels	A data set that is produced as the output of a class prediction data transformation and consists of a data set with assigned class labels.
http://purl.obolibrary.org/obo/OBI_0000202	investigation agent role	http://purl.obolibrary.org/obo/BFO_0000023	role	investigator	A role borne by an entity and that is realized in a process that is part of an investigation in which an objective is achieved. These processes include, among others: planning, overseeing, funding, reviewing.
http://purl.obolibrary.org/obo/OBI_0000456	material transformation objective	http://purl.obolibrary.org/obo/IAO_0000005	objective specification	artifact  creation objective	an objective specifiction that creates an specific output object from input materials.
http://purl.obolibrary.org/obo/OBI_0000648	clustered data set	http://purl.obolibrary.org/obo/IAO_0000100	homogenous data collection	data set with assigned discovered class labels	A data set that is produced as the output of a class discovery data transformation and consists of a data set with assigned discovered class labels.
http://purl.obolibrary.org/obo/OBI_0000659	specimen collection process	http://purl.obolibrary.org/obo/COB_0000035	completely executed planned process	specimen collection	A planned process with the objective to obtain a material entity for potential use as an input upon which measurements or observations are performed.
http://purl.obolibrary.org/obo/OBI_0000663	class prediction data transformation	http://purl.obolibrary.org/obo/OBI_0200000	data transformation	supervised classification data transformation	A class prediction data transformation (sometimes called supervised classification) is a data transformation that has objective class prediction.
http://purl.obolibrary.org/obo/OBI_0000674	center value	http://purl.obolibrary.org/obo/IAO_0000027	data entity	median	A data item that is produced as the output of a center calculation data transformation and represents the center value of the input data.
http://purl.obolibrary.org/obo/OBI_0000675	statistical hypothesis test objective	http://purl.obolibrary.org/obo/OBI_0200166	data transformation objective	hypothesis test objective	is a data transformation objective where the aim is to estimate statistical significance with the aim of proving or disproving a hypothesis by means of some data transformation.
http://purl.obolibrary.org/obo/OBI_0000679	average value	http://purl.obolibrary.org/obo/IAO_0000027	data entity	arithmetic mean	A  data item that is produced as the output of an averaging data transformation and represents the average value of the input data.
http://purl.obolibrary.org/obo/OBI_0000700	support vector machine	http://purl.obolibrary.org/obo/OBI_0000663	class prediction data transformation	SVM	A support vector machine is a data transformation with a class prediction objective based on the construction of a separating hyperplane that maximizes the margin between two data sets of vectors in n-dimensional space.
http://purl.obolibrary.org/obo/OBI_0000727	k-nearest neighbors	http://purl.obolibrary.org/obo/OBI_0200175	class discovery data transformation	k-NN	A k-nearest neighbors is a data transformation which achieves a class discovery or partitioning objective, in which an input data object with vector y is assigned to a class label based upon the k closest training data set points to y; where k is the largest value that class label is assigned.
http://purl.obolibrary.org/obo/OBI_0000749	CART	http://purl.obolibrary.org/obo/OBI_0000707	decision tree building data transformation	classification and regression trees	A CART (classification and regression trees) is a data transformation method for producing a classification or regression model with a tree-based structure.
http://purl.obolibrary.org/obo/OBI_0001479	specimen from organism	http://purl.obolibrary.org/obo/OBI_0100051	specimen	tissue specimen	A specimen that derives from an anatomical part or substance arising from an organism. Examples of tissue specimen include tissue, organ, physiological system, blood, or body location (arm).
http://purl.obolibrary.org/obo/OBI_0001755	selection criterion	http://purl.obolibrary.org/obo/IAO_0000033	directive information entity	selection rule	A directive information entity which defines and states a principle of standard by which selection process may take place.
http://purl.obolibrary.org/obo/OBI_0001928	selection	http://purl.obolibrary.org/obo/COB_0000035	completely executed planned process	selection process	A planned process with the objective to create a group of entities by applying a predefined criteria to a larger group of entities.
http://purl.obolibrary.org/obo/OBI_0200000	data transformation	http://purl.obolibrary.org/obo/COB_0000035	completely executed planned process	data processing	A completely executed planned process that produces output data from input data.
http://purl.obolibrary.org/obo/OBI_0200050	dimensionality reduction	http://purl.obolibrary.org/obo/OBI_0200175	class discovery data transformation	data projection	A dimensionality reduction is data partitioning which transforms each input m-dimensional vector (x_1, x_2, ..., x_m) into an output n-dimensional vector (y_1, y_2, ..., y_n), where n is smaller than m.
http://purl.obolibrary.org/obo/OBI_0200051	principal components analysis dimensionality reduction	http://purl.obolibrary.org/obo/OBI_0200050	dimensionality reduction	pca data reduction	A principal components analysis dimensionality reduction is a dimensionality reduction achieved by applying principal components analysis and by keeping low-order principal components and excluding higher-order ones.
http://purl.obolibrary.org/obo/OBI_0200111	data visualization	http://purl.obolibrary.org/obo/COB_0000035	completely executed planned process	data encoding as image	A planned process with the objective to graphically represent some data by inputing the data and outputting images, diagrams or animations.
http://purl.obolibrary.org/obo/OBI_0200175	class discovery data transformation	http://purl.obolibrary.org/obo/OBI_0200000	data transformation	unsupervised classification data transformation	A class discovery data transformation (sometimes called unsupervised classification) is a data transformation that has objective class discovery.
http://purl.obolibrary.org/obo/OBI_0200178	class discovery objective	http://purl.obolibrary.org/obo/OBI_0200166	data transformation objective	clustering objective	A class discovery objective (sometimes called unsupervised classification) is a data transformation objective where the aim is to organize input data  (typically vectors of attributes) into classes, where the number of classes and their specifications are not known a priori. Depending on usage, the class assignment can be definite or probabilistic.
http://purl.obolibrary.org/obo/OBI_0200179	class prediction objective	http://purl.obolibrary.org/obo/OBI_0200166	data transformation objective	classification objective	A class prediction objective (sometimes called supervised classification) is a data transformation objective where the aim is to create a predictor from training data through a machine learning technique. The training data consist of pairs of objects (typically vectors of attributes) and
class labels for these objects. The resulting predictor can be used to attach class labels to any valid novel input object. Depending on usage, the prediction can be definite or probabilistic. A classification is learned from the training data and can then be tested on test data.
http://purl.obolibrary.org/obo/OBI_0200188	cross validation objective	http://purl.obolibrary.org/obo/OBI_0200172	partitioning objective	rotation estimation objective	A cross validation objective is a data transformation objective in which the aim is to partition a sample of data into subsets such that the analysis is initially performed on a single subset, while the other subset(s) are retained for subsequent use in confirming and validating the initial analysis.
http://purl.obolibrary.org/obo/OBI_0500000	study design	http://purl.obolibrary.org/obo/IAO_0000104	plan specification	experimental design	A plan specification comprised of protocols (which may specify how and what kinds of data will be gathered) that are executed as part of an investigation and is realized during a study design execution.
http://purl.obolibrary.org/obo/OBI_0500026	eligibility criterion	http://purl.obolibrary.org/obo/OBI_0001755	selection criterion	eligibility rule	an eligibility criterion (rule) is_a selection criterion which 
defines and states the requirements (positive or negative) for an entity to be considered as suitable for a given task or participation in a process.
http://purl.obolibrary.org/obo/OBI_0500027	inclusion criterion	http://purl.obolibrary.org/obo/OBI_0500026	eligibility criterion	inclusion rule	an inclusion criterion (rule) is_a *eligibility criterion*  which defines and states a condition which, if met, makes an entity suitable for a given task or participation in a given process. For instance, in a study protocol, inclusion criteria indicate the conditions that prospective subjects MUST meet to be eligible for participation in a study.
http://purl.obolibrary.org/obo/OBCS_0000121	inferential statistical data analysis	http://purl.obolibrary.org/obo/OBCS_0000001	statistical data analysis	significantly statistical data analysis	A statistical data analysis that uses patterns in the sample data to draw inferences about the population represented, accounting for randomness.
http://purl.obolibrary.org/obo/OBCS_0000122	transformed data matrix	http://purl.obolibrary.org/obo/IAO_0000027	data entity	set of transformed data sets	A data item that consists of two or more data sets that are produced as the output of a data transformation.
http://purl.obolibrary.org/obo/OBCS_0000218	derived data from statistical analysis	http://purl.obolibrary.org/obo/OBCS_0000233	transformed data item	statistic	A data item that is derived from a statistical data analysis.
http://purl.obolibrary.org/obo/OBCS_0000219	derived data from descriptive statistical analysis	http://purl.obolibrary.org/obo/OBCS_0000218	derived data from statistical analysis	descriptive statistic	A data item that is derived from a descriptive statistical data analysis.
http://purl.obolibrary.org/obo/OBCS_0000220	derived data from inferential statistical analysis	http://purl.obolibrary.org/obo/OBCS_0000218	derived data from statistical analysis	inferential statistic	A data item that is derived from an inferential statistical data analysis.
http://purl.obolibrary.org/obo/IAO_0020000	identifier	http://purl.obolibrary.org/obo/IAO_0000030	information content entity	proper name	An information content entity that is the outcome of a dubbing process and is used to refer to one instance of entity shared by a group of people to refer to that individual entity.
http://purl.obolibrary.org/obo/IAO_0020010	identifier creating process	http://purl.obolibrary.org/obo/COB_0000035	completely executed planned process	naming	A planned process that provides a reference to an individual entity shared by a group of subscribers to refer to that individual entity.
http://purl.obolibrary.org/obo/OAE_0000001	adverse event	http://purl.obolibrary.org/obo/OGMS_0000061	pathological bodily process	adverse reaction	a pathological bodily process that occurs after a medical intervention. An adverse event is likely caused by the medical intervention; however, such a causal association is not required to be an adverse event.
http://purl.obolibrary.org/obo/OAE_0000005	adverse drug event	http://purl.obolibrary.org/obo/OAE_0000001	adverse event	drug adverse event	an adverse event that occurs after a drug administration
http://purl.obolibrary.org/obo/STATO_0000252	categorical variable	http://purl.obolibrary.org/obo/STATO_0000258	variable	qualitative factor	a categorical variable  is a variable  which that can only assume a finite number  of value and cast observation in a small number of categories
http://purl.obolibrary.org/obo/STATO_0000011	cartesian coordinate axis	http://purl.obolibrary.org/obo/STATO_0000007	axis	rectangular coordinate axis	a cartesian axis is one of 3 the axis in a cartesian coordinate system defining a referential in 3 dimensions. each of the axis is orthogonal to the other 2
http://purl.obolibrary.org/obo/STATO_0000113	variance	http://purl.obolibrary.org/obo/STATO_0000028	measure of dispersion	σ2	variance is a data item about a random variable or probability distribution. it is equivalent to the square of the standard deviation.  It is one of several descriptors of a probability distribution, describing how far the numbers lie from the mean (expected value).The variance is the second moment of a distribution.
http://purl.obolibrary.org/obo/STATO_0000150	minimum observed value	http://purl.obolibrary.org/obo/STATO_0000039	statistic	minimum value	a minimum value is a data item which denotes the smallest value found in a dataset or resulting from a calculation.
http://purl.obolibrary.org/obo/STATO_0000151	maximum observed value	http://purl.obolibrary.org/obo/STATO_0000039	statistic	maximum value	maximum value is a data item which denotes the largest value found in a dataset or resulting from a calculation.
http://purl.obolibrary.org/obo/STATO_0000237	standard deviation	http://purl.obolibrary.org/obo/STATO_0000028	measure of dispersion	σ	The standard deviation of a random variable, statistical population, data set, or probability distribution is a measure of variation which correspond to the average distance from the mean of the data set to any given point of that dataset. It also corresponds to the square root of its variance.
http://purl.obolibrary.org/obo/DUO_0000001	data use permission	http://purl.obolibrary.org/obo/IAO_0000027	data entity	consent code	A data item that is used to indicate consent permissions for datasets and/or materials, and relates to the purposes for which datasets and/or material might be removed, stored or used.
http://purl.obolibrary.org/obo/DUO_0000011	population origins or ancestry research only	http://purl.obolibrary.org/obo/DUO_0000001	data use permission	population origins/ancestry research	This data use permission indicates that use of the data is limited to the study of population origins or ancestry.
http://purl.obolibrary.org/obo/DUO_0000024	publication moratorium	http://purl.obolibrary.org/obo/DUO_0000017	data use modifier	publication embargo	This data use modifier indicates that requestor agrees not to publish results of studies until a specific date.
http://purl.obolibrary.org/obo/STATO_0000639	percentage	http://purl.obolibrary.org/obo/STATO_0000184	ratio	%	A ratio formed between a numerator and a denominator (both described by the same unit), and that is multiplied by 100.
http://purl.obolibrary.org/obo/OBI_0002210	histologic grade according to the Fuhrman Nuclear Grading System	http://purl.obolibrary.org/obo/OBI_0001930	categorical value specification	Histologic Grade (Fuhrman Nuclear Grading System)	A categorical value specification that is a histologic grade assigned to a tumor slide specimen according to the Fuhrman Nuclear Grading System.
http://purl.obolibrary.org/obo/OBI_0002224	pathologic primary tumor stage for colon and rectum according to AJCC 7th edition	http://purl.obolibrary.org/obo/OBI_0001930	categorical value specification	pT: Pathologic spread colorectal primary tumor (AJCC 7th Edition)	A categorical value specification that is a pathologic finding about one or more characteristics of colorectal cancer following the rules of the TNM American Joint Committee on Cancer (AJCC) version 7 classification system as they pertain to staging of the primary tumor. TNM pathologic primary tumor findings are based on clinical findings supplemented by histopathologic examination of one or more tissue specimens acquired during surgery.
http://purl.obolibrary.org/obo/OBI_0002232	pathologic primary tumor stage for lung according to AJCC 7th edition	http://purl.obolibrary.org/obo/OBI_0001930	categorical value specification	pT: Pathologic spread lung primary tumor (AJCC 7th Edition)	A categorical value specification that is a pathologic finding about one or more characteristics of lung cancer following the rules of the TNM American Joint Committee on Cancer (AJCC) version 7 classification system as they pertain to staging of the primary tumor. TNM pathologic primary tumor findings are based on clinical findings supplemented by histopathologic examination of one or more tissue specimens acquired during surgery.
http://purl.obolibrary.org/obo/OBI_0002243	pathologic primary tumor stage for kidney according to AJCC 7th edition	http://purl.obolibrary.org/obo/OBI_0001930	categorical value specification	pT: Pathologic spread kidney primary tumor (AJCC 7th Edition)	A categorical value specification that is a pathologic finding about one or more characteristics of renal cancer following the rules of the TNM AJCC v7 classification system as they pertain to staging of the primary tumor. TNM pathologic primary tumor findings are based on clinical findings supplemented by histopathologic examination of one or more tissue specimens acquired during surgery.
http://purl.obolibrary.org/obo/OBI_0002256	pathologic primary tumor stage for ovary according to AJCC 7th edition	http://purl.obolibrary.org/obo/OBI_0001930	categorical value specification	pT: Pathologic spread ovarian primary tumor (AJCC 7th Edition)	A categorical value specification that is a pathologic finding about one or more characteristics of ovarian cancer following the rules of the TNM AJCC v7 classification system as they pertain to staging of the primary tumor. TNM pathologic primary tumor findings are based on clinical findings supplemented by histopathologic examination of one or more tissue specimens acquired during surgery.
http://purl.obolibrary.org/obo/OBI_0002270	pathologic lymph node stage for colon and rectum according to AJCC 7th edition	http://purl.obolibrary.org/obo/OBI_0001930	categorical value specification	pN: Pathologic spread colon lymph nodes (AJCC 7th Edition)	A categorical value specification that is a pathologic finding about one or more characteristics of colorectal cancer following the rules of the TNM AJCC v7 classification system as they pertain to staging of regional lymph nodes.
http://purl.obolibrary.org/obo/OBI_0002279	pathologic lymph node stage for lung according to AJCC 7th edition	http://purl.obolibrary.org/obo/OBI_0001930	categorical value specification	pN: Pathologic spread colon lymph nodes (AJCC 7th Edition)	A categorical value specification that is a pathologic finding about one or more characteristics of lung cancer following the rules of the TNM AJCC v7 classification system as they pertain to staging of regional lymph nodes.
http://purl.obolibrary.org/obo/OBI_0002284	pathologic lymph node stage for kidney according to AJCC 7th edition	http://purl.obolibrary.org/obo/OBI_0001930	categorical value specification	pN: Pathologic spread kidney lymph nodes (AJCC 7th Edition)	A categorical value specification that is a pathologic finding about one or more characteristics of renal cancer following the rules of the TNM AJCC v7 classification system as they pertain to staging of regional lymph nodes.
http://purl.obolibrary.org/obo/OBI_0002287	pathologic lymph node stage for ovary according to AJCC 7th edition	http://purl.obolibrary.org/obo/OBI_0001930	categorical value specification	pN: Pathologic spread ovarian lymph nodes (AJCC 7th Edition)	A categorical value specification that is a pathologic finding about one or more characteristics of ovarian cancer following the rules of the TNM AJCC v7 classification system as they pertain to staging of regional lymph nodes.
http://purl.obolibrary.org/obo/OBI_0002290	pathologic distant metastases stage for colon according to AJCC 7th edition	http://purl.obolibrary.org/obo/OBI_0001930	categorical value specification	M: colon distant metastases (AJCC 7th Edition)	A categorical value specification that is a pathologic finding about one or more characteristics of colon cancer following the rules of the TNM AJCC v7 classification system as they pertain to distant metastases. TNM pathologic distant metastasis findings are based on clinical findings supplemented by histopathologic examination of one or more tissue specimens acquired during surgery.
http://purl.obolibrary.org/obo/OBI_0002298	pathologic distant metastases stage for lung according to AJCC 7th edition	http://purl.obolibrary.org/obo/OBI_0001930	categorical value specification	M: lung distant metastases (AJCC 7th Edition)	A categorical value specification that is a pathologic finding about one or more characteristics of lung cancer following the rules of the TNM AJCC v7 classification system as they pertain to distant metastases. TNM pathologic distant metastasis findings are based on clinical findings supplemented by histopathologic examination of one or more tissue specimens acquired during surgery.
http://purl.obolibrary.org/obo/OBI_0002306	pathologic distant metastases stage for kidney according to AJCC 7th edition	http://purl.obolibrary.org/obo/OBI_0001930	categorical value specification	M: kidney distant Metastases (AJCC 7th Edition)	A categorical value specification that is a pathologic finding about one or more characteristics of renal cancer following the rules of the TNM AJCC v7 classification system as they pertain to distant metastases. TNM pathologic distant metastasis findings are based on clinical findings supplemented by histopathologic examination of one or more tissue specimens acquired during surgery.
http://purl.obolibrary.org/obo/OBI_0002310	pathologic distant metastases stage for ovary according to AJCC 7th edition	http://purl.obolibrary.org/obo/OBI_0001930	categorical value specification	M: ovarian distant metastases (AJCC 7th Edition)	A categorical value specification that is a  pathologic finding about one or more characteristics of ovarian cancer following the rules of the TNM AJCC v7 classification system as they pertain to distant metastases. TNM pathologic distant metastasis findings are based on clinical findings supplemented by histopathologic examination of one or more tissue specimens acquired during surgery.
http://purl.obolibrary.org/obo/OBI_0002314	clinical tumor stage group according to AJCC 7th edition	http://purl.obolibrary.org/obo/OBI_0001930	categorical value specification	Clinical tumor stage group (AJCC 7th Edition)	A categorical value specification that is an assessment of the stage of a cancer according to the American Joint Committee on Cancer (AJCC) v7 staging systems.
http://purl.obolibrary.org/obo/OBI_0002326	International Federation of Gynecology and Obstetrics cervical cancer stage value specification	http://purl.obolibrary.org/obo/OBI_0001930	categorical value specification	Clinical FIGO stage	A categorical value specification that is an assessment of the stage of a gynecologic cancer according to the International Federation of Gynecology and Obstetrics (FIGO) staging systems.
http://purl.obolibrary.org/obo/OBI_0002341	International Federation of Gynecology and Obstetrics ovarian cancer stage value specification	http://purl.obolibrary.org/obo/OBI_0001930	categorical value specification	Pathologic Tumor Stage Grouping for ovarian cancer (FIGO)	A categorical value specification that is a pathologic finding about one or more characteristics of ovarian cancer following the rules of the FIGO classification system.
http://purl.obolibrary.org/obo/OBI_0002356	performance status value specification	http://purl.obolibrary.org/obo/OBI_0001930	categorical value specification	Performance Status Scale	A categorical value specification that is an assessment of a participant's performance status (general well-being and activities of daily life).
http://purl.obolibrary.org/obo/OBI_0002357	Eastern Cooperative Oncology Group score value specification	http://purl.obolibrary.org/obo/OBI_0002356	performance status value specification	ECOG score	A performance status value specification designed by the Eastern Cooperative Oncology Group to assess disease progression and its affect on the daily living abilities of the patient.
http://purl.obolibrary.org/obo/OBI_0002363	Karnofsky score vaue specification	http://purl.obolibrary.org/obo/OBI_0002356	performance status value specification	Karnofsky Score	A performance status value specification designed for classifying patients 16 years of age or older by their functional impairment.
http://purl.obolibrary.org/obo/STATO_0000574	center value	http://purl.obolibrary.org/obo/STATO_0000152	quartile	second quartile	The median is that value of the variate which divides the total frequency into two halves. The median is measure of central tendency of data. It is obtained by arranging the observations in order from smallest to largest value. If there is an odd number of observations, the median is the middle value. If there is an even number of observations, the median is the average of the two middle values.
http://purl.obolibrary.org/obo/IAO_0020020	code set	http://purl.obolibrary.org/obo/IAO_0000030	information content entity	code map	An information content entity that is a collection of other information content entities that has been created to identify or annotate things in a specified domain, and where the intention of its creators is that the collection has a one-to-one correspondence with those things.
http://purl.obolibrary.org/obo/IAO_0001000	data collection	http://purl.obolibrary.org/obo/IAO_0000027	data entity	data set	A data entity that consists of multiple data entities.
http://purl.obolibrary.org/obo/OBCS_0000120	data matrix	http://purl.obolibrary.org/obo/IAO_0000027	data entity	set of data sets	A data item that is more specifically a rectangular array of numbers, symbols, or expressions, arranged in rows and columns.
http://purl.obolibrary.org/obo/OAE_0000002	medical intervention	http://purl.obolibrary.org/obo/OBI_0000011	obsolete planned process		medical intervention is a planned process that has the goal of diagnosing, preventing or relieving illness or injury.
http://purl.obolibrary.org/obo/OAE_0000011	drug administration	http://purl.obolibrary.org/obo/OAE_0000002	medical intervention		a medical intervention where a patient is administered with a drug
http://purl.obolibrary.org/obo/OAE_0000012	medical device usage for medical intervention	http://purl.obolibrary.org/obo/OAE_0000002	medical intervention		a medical intervention that uses a medical device
http://purl.obolibrary.org/obo/OAE_0000096	adverse event induced by medical device	http://purl.obolibrary.org/obo/OAE_0002617	medical device adverse event		a medical device adverse event that is induced or caused by a medical device. There is a causal relation between the adverse event and the usage of a medical device.
http://purl.obolibrary.org/obo/OGMS_0000014	clinical finding	http://purl.obolibrary.org/obo/OGMS_0000123	clinical data item		A representation that is either the output of a clinical history taking or a physical examination or an image finding, or some combination thereof. A clinical statement about an organism that is the result of clinical observation or assessment, including observed signs, reported symptoms, and clinician-asserted findings.
http://purl.obolibrary.org/obo/NCIT_C208323	CTCAE Adverse Events Version 3.0	http://purl.obolibrary.org/obo/NCIT_C208319	Adverse Event by CTCAE Version		The adverse events according to Common Terminology Criteria for Adverse Events (CTCAE) Terminology version 3.0.
http://purl.obolibrary.org/obo/NCIT_C208319	Adverse Event by CTCAE Version	http://purl.obolibrary.org/obo/NCIT_C41331	Adverse Event		CTCAE Adverse Events that are organized according to the version of CTCAE.
http://purl.obolibrary.org/obo/PATO_0000051	morphology	http://purl.obolibrary.org/obo/PATO_0001241	physical object characteristic		A characterisitic of a single physical entity inhering in the bearer by virtue of the bearer's size or shape or structure.
http://purl.obolibrary.org/obo/PATO_0000141	structure	http://purl.obolibrary.org/obo/PATO_0000051	morphology		A morphology quality inhering in a bearer by virtue of the bearer's relative position, shape, arrangements and connectivity of an organism's various parts; the pattern underlying its form.
http://purl.obolibrary.org/obo/PATO_0001236	process characteristic	http://purl.obolibrary.org/obo/PATO_0000001	characteristic		A characteristic which inheres in a process.
http://purl.obolibrary.org/obo/PATO_0001241	physical object characteristic	http://purl.obolibrary.org/obo/PATO_0000001	characteristic		A characteristic which inheres in a continuant.
http://purl.obolibrary.org/obo/PATO_0001415	morbidity	http://purl.obolibrary.org/obo/PATO_0002003	population quality		A quality inhering in a population by virtue of the proportion of its members that are ill at a given time.
http://purl.obolibrary.org/obo/PATO_0001992	cellularity	http://purl.obolibrary.org/obo/PATO_0001995	organismal quality		An organismal quality inhering in a bearer by virtue of the bearer's consisting cells.
http://purl.obolibrary.org/obo/PATO_0001993	multicellular	http://purl.obolibrary.org/obo/PATO_0001992	cellularity		A cellularity quality inhering in a bearer by virtue of the bearer's consisting of more than one cell.
http://purl.obolibrary.org/obo/PATO_0002003	population quality	http://purl.obolibrary.org/obo/PATO_0001241	physical object characteristic		A quality that inheres in an entire population or part of a population.
http://purl.obolibrary.org/obo/PATO_0010001	disconnected	http://purl.obolibrary.org/obo/PATO_0000141	structure		A structural quality inhering in the bearer by virtue of the bearer consisting of multiple structures lacking any physical connection to each other.
http://purl.obolibrary.org/obo/NCIT_C17103	Risk Factor	http://purl.obolibrary.org/obo/NCIT_C20047	Diagnostic or Prognostic Factor		Any aspect of an individual's life, behavior, an environmental exposure, or an inborn or inherited characteristic that increases the likelihood of a disease, condition or injury.
http://purl.obolibrary.org/obo/NCIT_C41331	Adverse Event	http://purl.obolibrary.org/obo/NCIT_C36291	Finding by Cause		Any unfavorable or unintended disease, sign, or symptom (including an abnormal laboratory finding) that is temporally associated with the use of a medical treatment or procedure, and that may or may not be considered related to the medical treatment or procedure. Such events can be related to the intervention, dose, route of administration, patient, or caused by an interaction with another drug(s) or procedure(s).
http://purl.obolibrary.org/obo/OBI_0002555	age group inclusion criterion	http://purl.obolibrary.org/obo/OBI_0500027	inclusion criterion		An inclusion criterion that defines and states an age bracket which, if met, makes an entity suitable for a given task or participation in a given process.
http://purl.obolibrary.org/obo/OBI_0002556	minimum age value specification	http://purl.obolibrary.org/obo/OBI_0001933	value specification		A value specifcation that specifies the youngest age when specifying an age range.
http://purl.obolibrary.org/obo/OBI_0002557	maximum age value specification	http://purl.obolibrary.org/obo/OBI_0001933	value specification		A value specifcation that specifies the oldest age when specifying an age range.
http://purl.obolibrary.org/obo/STATO_0000722	quantitative variable	http://purl.obolibrary.org/obo/STATO_0000258	variable		A variable that can assume numerical values, with or without units of measure.
http://purl.obolibrary.org/obo/CMEO_0000003	wearable sensor	http://purl.obolibrary.org/obo/CMEO_0000002	wearable device		A wearable device that is worn on the body, or embedded in a wearable item, and that detects and records one or more physiological, behavioral, or environmental properties of a person over time.
http://purl.obolibrary.org/obo/CMEO_0000004	medical encounter	http://purl.obolibrary.org/obo/BFO_0000015	process		A process consisting of an interaction between a patient and one or more healthcare providers for the purpose of assessing, monitoring, or managing the patient's health, occurring at a point in time or over a time interval.
http://purl.obolibrary.org/obo/CMEO_0000008	variable derivation formula	http://purl.obolibrary.org/obo/IAO_0000030	information content entity		An information content entity that specifies a mathematical or logical expression used to compute a derived value from one or more input variables, parameters, or constants.
http://purl.obolibrary.org/obo/CMEO_0000009	data element	http://purl.obolibrary.org/obo/IAO_0000027	data entity		A basic unit of information that has a unique meaning and instances (data items) of distinct value. Examples of data elements include gender, race, and geographic location in data dictionary(ref. https://cde.nlm.nih.gov/). It provides classification of data elements
http://purl.obolibrary.org/obo/CMEO_0000010	clinical event record	http://purl.obolibrary.org/obo/IAO_0000027	data entity		An information content entity (a data item, e.g. a variable or record) that documents the occurrence of a clinically relevant event for a patient at a point in time or over a time interval (e.g., a death, a hospitalization, a myocardial infarction), and that is about the corresponding real-world process.
http://purl.obolibrary.org/obo/CMEO_0000011	bleeding event record	http://purl.obolibrary.org/obo/CMEO_0000010	clinical event record		A clinical event record that documents an occurrence of bleeding in a patient  -  the loss of blood from the circulatory system to an external site or into tissues or body cavities  -  at a specified time point or during a specified time interval.
http://purl.obolibrary.org/obo/CMEO_0000012	cardiovascular event record	http://purl.obolibrary.org/obo/CMEO_0000010	clinical event record		A clinical event record that documents an occurrence involving the heart or blood vessels in a patient at a specified time point or during a specified time interval, typically an acute episode or outcome relevant to cardiovascular health.
http://purl.obolibrary.org/obo/CMEO_0000013	adverse event record	http://purl.obolibrary.org/obo/CMEO_0000010	clinical event record		A clinical event record  that documents an untoward or harmful occurrence in a patient following a medical intervention (such as the administration of a drug, a procedure, or the use of a medical device), whether or not judged to be caused by it, and that is about the corresponding adverse-event process.
http://purl.obolibrary.org/obo/CMEO_0000014	adverse drug event record	http://purl.obolibrary.org/obo/CMEO_0000013	adverse event record		An adverse event record that documents an adverse event following, and associated with, the administration of a drug or biological product to a patient.
http://purl.obolibrary.org/obo/CMEO_0000015	allergic reaction record	http://purl.obolibrary.org/obo/CMEO_0000013	adverse event record		An adverse event record that documents a hypersensitivity reaction of the immune system occurring following exposure to an allergen such as a drug, food, or environmental substance.
http://purl.obolibrary.org/obo/CMEO_0000016	device adverse event record	http://purl.obolibrary.org/obo/CMEO_0000013	adverse event record		An adverse event record that documents an event caused by, or associated with, the use of a medical device, where there is a causal relation between the event and the use of that device.
http://purl.obolibrary.org/obo/CMEO_0000017	death record	http://purl.obolibrary.org/obo/CMEO_0000010	clinical event record		A clinical event record that documents the death of a patient, occurring at a specified time point or during a specified time interval.
http://purl.obolibrary.org/obo/CMEO_0000018	all-cause mortality	http://purl.obolibrary.org/obo/CMEO_0000017	death record		A mortality outcome record that documents the counts or indicates death occurring in a study population regardless of the underlying cause of death.
http://purl.obolibrary.org/obo/CMEO_0000019	cause-specific mortality	http://purl.obolibrary.org/obo/CMEO_0000017	death record		A mortality outcome record that documents the counts or indicates death occurring in a study population where the death is attributed to a specified cause category (e.g., cardiovascular, cancer, infection) according to a defined attribution method.
http://purl.obolibrary.org/obo/CMEO_0000021	hospitalization record	http://purl.obolibrary.org/obo/CMEO_0000010	clinical event record		A clinical event record that documents an inpatient hospital encounter in which a patient is admitted to a hospital for care (typically characterized by an admission and a discharge), and that is about the corresponding medical encounter process.
http://purl.obolibrary.org/obo/CMEO_0000027	device identifier	http://purl.obolibrary.org/obo/IAO_0020000	identifier		A device identifier is an identifier that identifies some device. [Allotrope]
http://purl.obolibrary.org/obo/CMEO_0000028	missing value specification	http://purl.obolibrary.org/obo/OBI_0001933	value specification		A value specification that specifies the value or code used in a dataset to indicate that the value of a data element is missing, not recorded, or not applicable (e.g., "NA", "-9", or an empty string).
http://purl.obolibrary.org/obo/CMEO_0000029	OMOP identifier	http://purl.obolibrary.org/obo/IAO_0000578	centrally registered identifier		An identifier that denotes an entity in the OMOP Common Data Model vocabulary, typically by referencing an OMOP concept identifier (concept_id) assigned to that entity.
http://purl.obolibrary.org/obo/CMEO_0000030	clinical measurement record	http://purl.obolibrary.org/obo/IAO_0000109	measurement datum		A measurement datum that documents a quantitative or ordinal assessment of a quality of an entity (typically a patient), obtained by applying a measurement procedure and recorded as a result value with an associated unit or scale when applicable.
http://purl.obolibrary.org/obo/CMEO_0000032	blood measurement record	http://purl.obolibrary.org/obo/CMEO_0000030	clinical measurement record		A clinical measurement record that documents a measurement of the blood or of its contents, such as cells, analytes or other components contained in the blood.
http://purl.obolibrary.org/obo/CMEO_0000033	blood biomarker measurement	http://purl.obolibrary.org/obo/CMEO_0000032	blood measurement record		A blood measurement record that documents the quantification of a biomarker, i.e., an analyte measured in a blood-derived specimen (whole blood, plasma, or serum) and used to indicate a biological state, physiological process, or pathological process (e.g., troponin, HbA1c, creatinine, CRP).
http://purl.obolibrary.org/obo/CMEO_0000034	protein biomarker measurement record	http://purl.obolibrary.org/obo/CMEO_0000030	clinical measurement record		A clinical measurement record that documents the quantification of a protein or of a measurable attribute of a protein (such as concentration or activity), used to indicate a biological state, physiological process, or pathological process, measured in a biological specimen such as blood, urine, or tissue (e.g., troponin, BNP/NT-proBNP, CRP, albumin).
http://purl.obolibrary.org/obo/CMEO_0000035	cardiovascular measurement record	http://purl.obolibrary.org/obo/CMEO_0000030	clinical measurement record		A clinical measurement record that documents a measurement of some part or function of the cardiovascular system, such as blood pressure, heart rate or left ventricular ejection fraction.
http://purl.obolibrary.org/obo/CMEO_0000036	consumption measurement record	http://purl.obolibrary.org/obo/CMEO_0000030	clinical measurement record		A clinical measurement record that documents the amount or frequency of intake or ingestion of a substance, such as food, drink, alcohol or tobacco.
http://purl.obolibrary.org/obo/CMEO_0000037	diagnostic measurement record	http://purl.obolibrary.org/obo/CMEO_0000030	clinical measurement record		A clinical measurement record that documents the output of a diagnostic device or the outcome of a diagnostic test used in the diagnosis of a medical condition.
http://purl.obolibrary.org/obo/CMEO_0000038	functional and behavioral assessment score	http://purl.obolibrary.org/obo/CMEO_0000030	clinical measurement record		A clinical measurement record that documents a score summarizing the functional or behavioral status of a person, derived from a standardized assessment instrument and recorded as a single numeric or ordinal result (e.g., Barthel Index, Katz ADL, NYHA class, MMSE, MoCA, PHQ-9, GAD-7, KCCQ, EQ-5D).
http://purl.obolibrary.org/obo/CMEO_0000039	clinical assessment scale record	http://purl.obolibrary.org/obo/CMEO_0000030	clinical measurement record		A clinical measurement record that documents the level, grade, stage, or severity category assigned to a clinical condition, functional status, or other health-related state using a standardized assessment scale with predefined criteria.
http://purl.obolibrary.org/obo/CMEO_0000040	time to event measurement record	http://purl.obolibrary.org/obo/IAO_0000582	time stamped measurement datum		A timestamped measurement datum that documents the elapsed time from a specified reference time point (e.g., baseline, diagnosis, treatment start) to the occurrence of a specified event, typically expressed in a time unit.
http://purl.obolibrary.org/obo/CMEO_0000043	therapeutic intervention record	http://purl.obolibrary.org/obo/CMEO_0000010	clinical event record		An information content entity (a data item) that documents whether, and which, therapeutic intervention  -  a medication exposure or a non-pharmacological therapy intended to prevent, manage, or treat a clinical condition  -  was administered to or planned for a patient, and that is about the corresponding intervention process.
http://purl.obolibrary.org/obo/CMEO_0000044	patient characteristic record	http://purl.obolibrary.org/obo/IAO_0000027	data entity		A data entity that documents a characteristic of a patient, such as a demographic attribute, lifestyle factor, risk factor or treatment adherence, obtained through observation, examination or reporting, and that is not a diagnosis, procedure or medication exposure.
http://purl.obolibrary.org/obo/CMEO_0000045	treatment adherence record	http://purl.obolibrary.org/obo/CMEO_0000044	patient characteristic record		A patient characteristic record that documents the extent to which a patient's behavior corresponds to an agreed therapeutic plan, such as taking medication as prescribed or following a recommended therapy regimen.
http://purl.obolibrary.org/obo/CMEO_0000046	demographic record	http://purl.obolibrary.org/obo/CMEO_0000044	patient characteristic record		A patient characteristic record that documents relatively stable characteristics of a person that are used to characterize individuals or populations (e.g., age, sex, ethnicity, education, occupation), typically not representing diagnoses, procedures, or measurements of physiological state.
http://purl.obolibrary.org/obo/CMEO_0000048	lifestyle factor record	http://purl.obolibrary.org/obo/CMEO_0000044	patient characteristic record		A patient characteristic record that documents a person's habitual behaviors, exposures, or daily living patterns that may affect health (e.g., smoking, alcohol use, diet, physical activity, sleep), typically reported by the person or observed over time.
http://purl.obolibrary.org/obo/CMEO_0000049	risk factor record	http://purl.obolibrary.org/obo/CMEO_0000044	patient characteristic record		A patient characteristic record that documents a characteristic, exposure, behavior, or measurable attribute that is associated with an increased or decreased probability of a specified health outcome or condition.
http://purl.obolibrary.org/obo/CMEO_0000050	procedure record	http://purl.obolibrary.org/obo/CMEO_0000010	clinical event record		An information content entity (a data item) that documents whether, and which, healthcare procedure was performed on or for a patient for diagnostic, therapeutic, preventive, or supportive purposes, and that is about the corresponding procedure process.
http://purl.obolibrary.org/obo/CMEO_0000051	sign or symptom	http://purl.obolibrary.org/obo/OGMS_0000014	clinical finding		A clinical finding that is either an objectively observed indication of a patient's state (a sign) or a subjectively experienced and reported complaint (a symptom).
http://purl.obolibrary.org/obo/CMEO_0000052	sign	http://purl.obolibrary.org/obo/CMEO_0000051	sign or symptom		An objective clinical finding that can be observed, measured, or elicited by an examiner or device, indicating some aspect of a patient's state.
http://purl.obolibrary.org/obo/CMEO_0000053	cardiac sign	http://purl.obolibrary.org/obo/CMEO_0000052	sign		A sign observed or measured in clinical assessment that indicates cardiovascular function or pathology (e.g., heart murmur, gallop rhythm, elevated jugular venous pressure, peripheral edema when used as a cardiac finding).
http://purl.obolibrary.org/obo/CMEO_0000054	general sign	http://purl.obolibrary.org/obo/CMEO_0000052	sign		A sign that is not specific to a single organ system and reflects general physiological or systemic status (e.g., fever, weight loss, fatigue when treated as an observable sign, pallor).
http://purl.obolibrary.org/obo/CMEO_0000055	neurological sign	http://purl.obolibrary.org/obo/CMEO_0000052	sign		A sign observed or elicited during neurological assessment that indicates nervous system function or dysfunction (e.g., abnormal reflexes, focal weakness on exam, abnormal gait, pupillary abnormalities).
http://purl.obolibrary.org/obo/CMEO_0000056	respiratory sign	http://purl.obolibrary.org/obo/CMEO_0000052	sign		A sign observed, elicited, or measured during clinical assessment that indicates respiratory system function or pathology (e.g., wheeze, crackles, use of accessory muscles, abnormal respiratory rate, low oxygen saturation when treated as a clinical sign).
http://purl.obolibrary.org/obo/CMEO_0000058	vital sign	http://purl.obolibrary.org/obo/CMEO_0000052	sign		A sign that reflects basic physiological function and is routinely measured in clinical assessment (e.g., blood pressure, heart rate, respiratory rate, body temperature, oxygen saturation).
http://purl.obolibrary.org/obo/CMEO_0000059	data type	http://purl.obolibrary.org/obo/IAO_0000027	data entity		A data entity that specifies the kind of values a variable may take, such as integer, floating-point number, string, boolean, or dateTime.
http://purl.obolibrary.org/obo/CMEO_0000061	timeline specification	http://purl.obolibrary.org/obo/IAO_0000104	plan specification		An information content entity that specifies the planned temporal structure of a study, including the sequence of study periods or visits and the timing constraints for when assessments, interventions, and outcomes are collected or evaluated.
http://purl.obolibrary.org/obo/CMEO_0000062	study design variable specification	http://purl.obolibrary.org/obo/IAO_0000104	plan specification		An information content entity that specifies the set of variables (data elements) to be collected or derived in a study, as part of the overall study design, including any constraints on what is recorded, when it is recorded, and how it is represented.
http://purl.obolibrary.org/obo/CMEO_0000063	study outcome specification	http://purl.obolibrary.org/obo/IAO_0000104	plan specification		A Study Outcome/Endpoint Specification is a Plan Specification that defines the measurable variables used to assess the effectiveness or impact of an intervention, treatment, or observation within a study. Endpoints are classified into Primary Endpoints (the main variable of interest) and Secondary Endpoints (additional measures that provide supporting information).
http://purl.obolibrary.org/obo/CMEO_0000066	retrospective study design	http://purl.obolibrary.org/obo/OBI_0500000	study design		A study in which participants with known outcomes are assessed based on data collected before the study.
http://purl.obolibrary.org/obo/CMEO_0000069	surgical procedure history exclusion criterion	http://purl.obolibrary.org/obo/CMEO_0000070	medical exposure exclusion criterion		An exclusion criterion that defines a condition under which a participant is ineligible for a study because they have a history of a specified surgical procedure occurring before a defined reference time point, optionally within a specified look-back period.
http://purl.obolibrary.org/obo/CMEO_0000071	comparator specification	http://purl.obolibrary.org/obo/IAO_0000033	directive information entity		It refers to a benchmark or reference against which the effects of a medical intervention are compared. In clinical trials, the comparator can be a placebo (an inactive substance designed to resemble the drug being tested), a different dose or regimen of the drug being studied, or a different drug altogether. The choice of comparator is a critical aspect of clinical trial design and can significantly impact the interpretation and applicability of the trial's results.
http://purl.obolibrary.org/obo/CMEO_0000072	intervention specification	http://purl.obolibrary.org/obo/IAO_0000033	directive information entity		In clinical studies, Intervention specification involves a detailed, precise, and a priori definition of the treatment, procedure, or behavioral regimen being tested to ensure reproducibility, accurate implementation, and valid evaluation of outcomes
http://purl.obolibrary.org/obo/CMEO_0000073	exploratory data analysis	http://purl.obolibrary.org/obo/OBI_0200000	data transformation		A data analysis process that summarizes and visualizes data to assess distributions, data quality, missingness, and relationships among variables, typically prior to modeling or inference.
http://purl.obolibrary.org/obo/CMEO_0000074	start time	http://purl.obolibrary.org/obo/IAO_0000582	time stamped measurement datum		A time stamped measurement datum that records the dateTime at which a process, interval, observation, or study period begins.
http://purl.obolibrary.org/obo/CMEO_0000075	end time	http://purl.obolibrary.org/obo/IAO_0000582	time stamped measurement datum		A time stamped measurement datum that records the dateTime at which a process, interval, observation, or study period ends.
http://purl.obolibrary.org/obo/CMEO_0000077	temporal dataset	http://purl.obolibrary.org/obo/IAO_0000100	homogenous data collection		A homogeneous data collection whose member measurement data are collected over time according to a study protocol that has a timeline specification, so that observations are associated with visits or timepoints.
http://purl.obolibrary.org/obo/CMEO_0000078	permission specification	http://purl.obolibrary.org/obo/IAO_0000033	directive information entity		An information content entity that specifies what actions are permitted for a given agent (or role) over a specified resource, under stated conditions and constraints.
http://purl.obolibrary.org/obo/CMEO_0000079	data access	http://purl.obolibrary.org/obo/COB_0000035	completely executed planned process		A planned process in which an agent obtains access to a data resource, resulting in the ability to view, retrieve, query, or otherwise use the data; such access may be governed by specified permissions and constraints.
http://purl.obolibrary.org/obo/CMEO_0000081	duration of observation	http://purl.obolibrary.org/obo/IAO_0000582	time stamped measurement datum		A time stamped measurement datum that records the length of the time interval over which a participant or entity is observed or followed up in a study (e.g., total follow-up time).
http://purl.obolibrary.org/obo/CMEO_0000083	composite endpoint specification	http://purl.obolibrary.org/obo/CMEO_0000063	study outcome specification		A clinical endpoint specification that defines a primary or secondary endpoint as a combination of two or more distinct component outcomes, assessed jointly to evaluate a research hypothesis in a clinical study.
http://purl.obolibrary.org/obo/BFO_0000002	continuant	http://purl.obolibrary.org/obo/BFO_0000001	entity		An entity that exists in full at any time in which it exists at all, persists through time while maintaining its identity and has no temporal parts.
http://purl.obolibrary.org/obo/BFO_0000003	occurrent	http://purl.obolibrary.org/obo/BFO_0000001	entity		An entity that has temporal parts and that happens, unfolds or develops through time.
http://purl.obolibrary.org/obo/BFO_0000004	independent continuant	http://purl.obolibrary.org/obo/BFO_0000002	continuant		b is an independent continuant = Def. b is a continuant which is such that there is no c and no t such that b s-depends_on c at t. (axiom label in BFO2 Reference: [017-002])
http://purl.obolibrary.org/obo/BFO_0000015	process	http://purl.obolibrary.org/obo/BFO_0000003	occurrent		p is a process = Def. p is an occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. (axiom label in BFO2 Reference: [083-003])
http://purl.obolibrary.org/obo/BFO_0000017	realizable entity	http://purl.obolibrary.org/obo/BFO_0000020	specifically dependent continuant		A specifically dependent continuant  that inheres in continuant  entities and are not exhibited in full at every time in which it inheres in an entity or group of entities. The exhibition or actualization of a realizable entity is a particular manifestation, functioning or process that occurs under certain circumstances.
http://purl.obolibrary.org/obo/BFO_0000020	specifically dependent continuant	http://purl.obolibrary.org/obo/BFO_0000002	continuant		b is a specifically dependent continuant = Def. b is a continuant & there is some independent continuant c which is not a spatial region and which is such that b s-depends_on c at every time t during the course of b’s existence. (axiom label in BFO2 Reference: [050-003])
http://purl.obolibrary.org/obo/BFO_0000023	role	http://purl.obolibrary.org/obo/BFO_0000017	realizable entity		A realizable entity  the manifestation of which brings about some result or end that is not essential to a continuant  in virtue of the kind of thing that it is but that can be served or participated in by that kind of continuant  in some kinds of natural, social or institutional contexts.
http://purl.obolibrary.org/obo/BFO_0000031	generically dependent continuant	http://purl.obolibrary.org/obo/BFO_0000002	continuant		b is a generically dependent continuant = Def. b is a continuant that g-depends_on one or more other entities. (axiom label in BFO2 Reference: [074-001])
http://purl.obolibrary.org/obo/BFO_0000040	material entity	http://purl.obolibrary.org/obo/BFO_0000004	independent continuant		An independent continuant that is spatially extended whose identity is independent of that of other entities and can be maintained through time.
http://purl.obolibrary.org/obo/IAO_0000003	measurement unit label	http://purl.obolibrary.org/obo/IAO_0000009	datum label		A measurement unit label is as a label that is part of a scalar measurement datum and denotes a unit of measure.
http://purl.obolibrary.org/obo/IAO_0000007	action specification	http://purl.obolibrary.org/obo/IAO_0000033	directive information entity		A directive information entity that describes an action the bearer will take.
http://purl.obolibrary.org/obo/IAO_0000009	datum label	http://purl.obolibrary.org/obo/IAO_0000030	information content entity		A label is a symbol that is part of some other datum and is used to either partially define  the denotation of that datum or to provide a means for identifying the datum as a member of the set of data with the same label
http://purl.obolibrary.org/obo/IAO_0000010	software	http://purl.obolibrary.org/obo/IAO_0000104	plan specification		Software is a plan specification composed of a series of instructions that can be 
interpreted by or directly executed by a processing unit.
http://purl.obolibrary.org/obo/IAO_0000028	symbol	http://purl.obolibrary.org/obo/IAO_0000030	information content entity		An information content entity that is a mark(s) or character(s) used as a conventional representation of another entity.
http://purl.obolibrary.org/obo/IAO_0000030	information content entity	http://purl.obolibrary.org/obo/BFO_0000031	generically dependent continuant		A generically dependent continuant that is about some thing.
http://purl.obolibrary.org/obo/IAO_0000032	scalar measurement datum	http://purl.obolibrary.org/obo/IAO_0000109	measurement datum		A scalar measurement datum is a measurement datum that is composed of two parts, numerals and a unit label.
http://purl.obolibrary.org/obo/IAO_0000033	directive information entity	http://purl.obolibrary.org/obo/IAO_0000030	information content entity		An information content entity whose concretizations indicate to their bearer how to realize them in a process.
http://purl.obolibrary.org/obo/IAO_0000037	dot plot	http://purl.obolibrary.org/obo/IAO_0000038	graph		A dot plot is a report graph which is a graphical representation of data where each data point is represented by a single dot placed on coordinates corresponding to data point values in particular dimensions.
http://purl.obolibrary.org/obo/IAO_0000038	graph	http://purl.obolibrary.org/obo/IAO_0000309	diagram		A diagram that presents one or more tuples of information by mapping those tuples in to a two dimensional space in a non arbitrary way.
http://purl.obolibrary.org/obo/IAO_0000064	algorithm	http://purl.obolibrary.org/obo/IAO_0000104	plan specification		A plan specification which describes the inputs and output of mathematical functions as well as workflow of execution for achieving an predefined objective. Algorithms are realized usually by means of implementation as computer programs for execution by automata.
http://purl.obolibrary.org/obo/IAO_0000078	curation status specification	http://purl.obolibrary.org/obo/IAO_0000102	data about an ontology part		The curation status of the term. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value.
http://purl.obolibrary.org/obo/IAO_0000096	source code module	http://purl.obolibrary.org/obo/IAO_0000033	directive information entity		A source code module is a directive information entity that specifies, using a programming language, some algorithm.
http://purl.obolibrary.org/obo/IAO_0000098	data format specification	http://purl.obolibrary.org/obo/IAO_0000033	directive information entity		A data format specification is the information content borne by the document published defining the specification.
Example: The ISO document specifying what encompasses an XML document; The instructions in a XSD file
http://purl.obolibrary.org/obo/IAO_0000101	image	http://purl.obolibrary.org/obo/IAO_0000308	figure		An image is an affine projection to a two dimensional surface, of measurements of some quality of an entity or entities repeated at regular intervals across a spatial range, where the measurements are represented as color and luminosity on the projected on surface.
http://purl.obolibrary.org/obo/IAO_0000102	data about an ontology part	http://purl.obolibrary.org/obo/IAO_0000027	data entity		Data about an ontology part is a data item about a part of an ontology, for example a term
http://purl.obolibrary.org/obo/IAO_0000104	plan specification	http://purl.obolibrary.org/obo/IAO_0000033	directive information entity		A directive information entity with action specifications and objective specifications as parts, and that may be concretized as a realizable entity that, if realized, is realized in a process in which the bearer tries to achieve the objectives by taking the actions specified.
http://purl.obolibrary.org/obo/IAO_0000109	measurement datum	http://purl.obolibrary.org/obo/IAO_0000027	data entity		A measurement datum is an information content entity that is a recording of the output of a measurement such as produced by a device.
http://purl.obolibrary.org/obo/IAO_0000179	histogram	http://purl.obolibrary.org/obo/IAO_0000038	graph		A histogram is a report graph which is a statistical description of a
distribution in terms of occurrence frequencies of different event classes.
http://purl.obolibrary.org/obo/IAO_0000180	heatmap	http://purl.obolibrary.org/obo/IAO_0000038	graph		A heatmap is a report graph which is a graphical representation of data
where the values taken by a variable(s) are shown as colors in a
two-dimensional map.
http://purl.obolibrary.org/obo/IAO_0000183	dendrogram	http://purl.obolibrary.org/obo/IAO_0000038	graph		A dendrogram is a report graph which is a tree diagram
frequently used to illustrate the arrangement of the clusters produced by a
clustering algorithm.
http://purl.obolibrary.org/obo/IAO_0000225	obsolescence reason specification	http://purl.obolibrary.org/obo/IAO_0000102	data about an ontology part		The reason for which a term has been deprecated. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value.
http://purl.obolibrary.org/obo/IAO_0000308	figure	http://purl.obolibrary.org/obo/IAO_0000030	information content entity		An information content entity consisting of a two dimensional arrangement of information content entities such that the arrangement itself is about something.
http://purl.obolibrary.org/obo/IAO_0000309	diagram	http://purl.obolibrary.org/obo/IAO_0000308	figure		A figure that expresses one or more propositions
http://purl.obolibrary.org/obo/IAO_0000310	document	http://purl.obolibrary.org/obo/IAO_0000030	information content entity		A collection of information content entities intended to be understood together as a whole
http://purl.obolibrary.org/obo/IAO_0000409	denotator type	http://purl.obolibrary.org/obo/IAO_0000102	data about an ontology part		A denotator type indicates how a term should be interpreted from an ontological perspective.
http://purl.obolibrary.org/obo/IAO_0000416	time measurement datum	http://purl.obolibrary.org/obo/IAO_0000032	scalar measurement datum		A scalar measurement datum that is the result of measuring a temporal interval
http://purl.obolibrary.org/obo/IAO_0000572	documenting	http://purl.obolibrary.org/obo/COB_0000035	completely executed planned process		A planned process in which a document is created or added to by including the specified input in it.
http://purl.obolibrary.org/obo/OBI_0000017	regulatory role	http://purl.obolibrary.org/obo/BFO_0000023	role		a role which inheres in material entities and is realized in the processes of making, enforcing or being defined by legislation or orders issued by a governmental body.
http://purl.obolibrary.org/obo/OBI_0000066	investigation	http://purl.obolibrary.org/obo/COB_0000035	completely executed planned process		a planned process that consists of parts: planning, study design execution, documentation and which produce conclusion(s).
http://purl.obolibrary.org/obo/OBI_0000071	quantitative confidence value	http://purl.obolibrary.org/obo/IAO_0000027	data entity		A data item which is used to indicate the degree of uncertainty about a measurement.
http://purl.obolibrary.org/obo/OBI_0000097	participant under investigation role	http://purl.obolibrary.org/obo/BFO_0000023	role		A role that is realized through the execution of a study design in which the bearer of the role participates and in which data about that bearer is collected.
http://purl.obolibrary.org/obo/OBI_0000112	specimen role	http://purl.obolibrary.org/obo/BFO_0000023	role		A role borne by a material entity that is obtained during a specimen collection process and that can be realized by performing measurements or observations on the specimen.
http://purl.obolibrary.org/obo/OBI_0000181	population	http://purl.obolibrary.org/obo/BFO_0000040	material entity		a population is a collection of individuals from the same taxonomic class living, counted or sampled at a particular site or in a particular area
http://purl.obolibrary.org/obo/OBI_0000245	organization	http://purl.obolibrary.org/obo/BFO_0000040	material entity		An entity that can bear roles, has members, and has a set of organization rules. Members of organizations are either organizations themselves or individual people. Members can bear specific organization member roles that are determined in the organization rules. The organization rules also determine how decisions are made on behalf of the organization by the organization members.
http://purl.obolibrary.org/obo/OBI_0000260	plan	http://purl.obolibrary.org/obo/BFO_0000017	realizable entity		A plan is a realizable entity that is the inheres in a bearer who is committed to realizing it as a completely executed planned process.
http://purl.obolibrary.org/obo/OBI_0000272	protocol	http://purl.obolibrary.org/obo/IAO_0000104	plan specification		A plan specification which has sufficient level of detail and quantitative information to communicate it between investigation agents, so that different investigation agents will reliably be able to independently reproduce the process.
http://purl.obolibrary.org/obo/OBI_0000338	drawing a conclusion based on data	http://purl.obolibrary.org/obo/COB_0000035	completely executed planned process		A planned process in which data gathered in an investigation is evaluated in the context of existing knowledge with the objective to generate more general conclusions or to conclude that the data does not allow one to draw general conclusion
http://purl.obolibrary.org/obo/OBI_0000339	planning	http://purl.obolibrary.org/obo/BFO_0000015	process		a process of creating or modifying a plan specification
http://purl.obolibrary.org/obo/OBI_0000419	reverse transcriptase	http://purl.obolibrary.org/obo/OBI_0000427	enzyme		enzyme and has_function some GO:0003964 (RNA-directed DNA polymerase
activity)
http://purl.obolibrary.org/obo/OBI_0000425	averaging objective	http://purl.obolibrary.org/obo/OBI_0200166	data transformation objective		An averaging objective is a data transformation objective where the aim is to perform mean calculations on the input of the data transformation.
http://purl.obolibrary.org/obo/OBI_0000427	enzyme	http://purl.obolibrary.org/obo/BFO_0000040	material entity		(protein or rna) or has_part (protein or rna) and
has_function some GO:0003824 (catalytic activity)
http://purl.obolibrary.org/obo/OBI_0000450	regulatory agency	http://purl.obolibrary.org/obo/OBI_0000245	organization		A regulatory agency is a organization that has responsibility over or for  the legislation (acts and regulations) for a given sector of the government.
http://purl.obolibrary.org/obo/OBI_0000453	measure function	http://purl.obolibrary.org/obo/BFO_0000034	function		Measure function is a function that is borne by a processed material  and realized in a process in which information about some entity is expressed relative to some reference.
http://purl.obolibrary.org/obo/OBI_0000457	manufacturing	http://purl.obolibrary.org/obo/COB_0000035	completely executed planned process		A planned process with the objective to produce a processed material which will have a function for future use.
http://purl.obolibrary.org/obo/OBI_0000458	manufacturing objective	http://purl.obolibrary.org/obo/OBI_0000456	material transformation objective		is the objective to manufacture a material of a certain function (device)
http://purl.obolibrary.org/obo/OBI_0000471	study design execution	http://purl.obolibrary.org/obo/COB_0000035	completely executed planned process		a planned process that carries out a study design
http://purl.obolibrary.org/obo/OBI_0000571	manufacturer role	http://purl.obolibrary.org/obo/BFO_0000023	role		Manufacturer role is a role which inheres in a person or organization and which is realized by a manufacturing process.
http://purl.obolibrary.org/obo/OBI_0000649	data set of features	http://purl.obolibrary.org/obo/IAO_0000100	homogenous data collection		A data set that is produced as the output of a descriptive statistical calculation data transformation and consists of producing a data set that represents one or more features of interest about the input data set.
http://purl.obolibrary.org/obo/OBI_0000673	statistical hypothesis test	http://purl.obolibrary.org/obo/OBI_0200000	data transformation		A statistical hypothesis test data transformation is a data transformation that has objective statistical hypothesis test.
http://purl.obolibrary.org/obo/OBI_0000684	specimen collection objective	http://purl.obolibrary.org/obo/IAO_0000005	objective specification		A objective specification that is fulfilled by obtaining a material entity for potential use as an input upon which measurements or observations are performed.
http://purl.obolibrary.org/obo/OBI_0000704	decision tree induction objective	http://purl.obolibrary.org/obo/OBI_0200166	data transformation objective		A decision tree induction objective is a data transformation objective in which a tree-like graph of edges and nodes is created and from which the selection of each branch requires that some type of logical decision is made.
http://purl.obolibrary.org/obo/OBI_0000707	decision tree building data transformation	http://purl.obolibrary.org/obo/OBI_0200000	data transformation		A decision tree building data transformation is a data transformation that has objective decision tree induction.
http://purl.obolibrary.org/obo/OBI_0000713	GenePattern software	http://purl.obolibrary.org/obo/IAO_0000010	software		a software that provides access to more than 100 tools for gene expression analysis, proteomics, SNP analysis and common data processing tasks.
http://purl.obolibrary.org/obo/OBI_0000726	peak matching	http://purl.obolibrary.org/obo/OBI_0200000	data transformation		Peak matching is a data transformation performed on a dataset of a graph of ordered data points (e.g. a spectrum) with the objective of pattern matching local maxima above a noise threshold
http://purl.obolibrary.org/obo/OBI_0000792	statistical model validation	http://purl.obolibrary.org/obo/OBI_0200171	partitioning data transformation		A data transformation which assesses how the results of a statistical analysis will generalize to an independent data set.
http://purl.obolibrary.org/obo/OBI_0000810	informed consent process	http://purl.obolibrary.org/obo/COB_0000035	completely executed planned process		A planned process with the objective to inform a person or their legal representative of legally and ethically relevant facts about a process that the person in question is asked to participate in, and which results in a documented decision as to whether the person in question will participate.
http://purl.obolibrary.org/obo/OBI_0000832	measurement device	http://purl.obolibrary.org/obo/COB_0001300	device		A device in which a measure function inheres.
http://purl.obolibrary.org/obo/OBI_0000835	manufacturer	http://purl.obolibrary.org/obo/BFO_0000040	material entity		A person or organization that has a manufacturer role.
http://purl.obolibrary.org/obo/OBI_0000947	service provider role	http://purl.obolibrary.org/obo/BFO_0000023	role		is a role which inheres in a person or organization and is realized in in a planned process which provides access to training, materials or execution of protocols for an organization or person
http://purl.obolibrary.org/obo/OBI_0000953	processed specimen	http://purl.obolibrary.org/obo/COB_0000026	processed material entity		A specimen that has been intentionally physically modified.
http://purl.obolibrary.org/obo/OBI_0000963	categorical label	http://purl.obolibrary.org/obo/IAO_0000009	datum label		A label that is part of a categorical datum and that indicates the value of the data item on the categorical scale.
http://purl.obolibrary.org/obo/OBI_0001000	questionnaire	http://purl.obolibrary.org/obo/IAO_0000310	document		A document with a set of printed or written questions with a choice of answers, devised for the purposes of a survey or statistical study.
http://purl.obolibrary.org/obo/OBI_0001468	cell specimen	http://purl.obolibrary.org/obo/OBI_0001479	specimen from organism		A specimen primarily composed of a cell or cells collected from a multicellular organism or a cell culture.
http://purl.obolibrary.org/obo/OBI_0001687	contact representative role	http://purl.obolibrary.org/obo/BFO_0000023	role		A role inhering in a person who represents an institution, organization, or service provider and realized when communication is directed at them about the entity they represent.
http://purl.obolibrary.org/obo/OBI_0001909	conclusion based on data	http://purl.obolibrary.org/obo/IAO_0000030	information content entity		An information content entity that is inferred from data.
http://purl.obolibrary.org/obo/OBI_0001930	categorical value specification	http://purl.obolibrary.org/obo/OBI_0001933	value specification		A value specification that is specifies one category out of a fixed number of nominal categories
http://purl.obolibrary.org/obo/OBI_0001933	value specification	http://purl.obolibrary.org/obo/IAO_0000030	information content entity		An information content entity that specifies a value within a classification scheme or on a quantitative scale.
http://purl.obolibrary.org/obo/OBI_0002076	collection of specimens	http://purl.obolibrary.org/obo/BFO_0000040	material entity		A material entity that has two or more specimens as its parts.
http://purl.obolibrary.org/obo/OBI_0100051	specimen	http://purl.obolibrary.org/obo/BFO_0000040	material entity		A material entity that is collected for potential use as an input upon which measurements or observations are performed.
http://purl.obolibrary.org/obo/OBI_0200033	leave one out cross validation method	http://purl.obolibrary.org/obo/OBI_0000792	statistical model validation		is a data transformation :  leave-one-out cross-validation (LOOCV) involves using a single observation from the original sample as the validation data, and the remaining observations as the training data. This is repeated such that each observation in the sample is used once as the validation data
http://purl.obolibrary.org/obo/OBI_0200041	k-means clustering	http://purl.obolibrary.org/obo/OBI_0200175	class discovery data transformation		A k-means clustering is a data transformation which achieves a class discovery or partitioning objective, which takes as input a collection of objects (represented as points in multidimensional space) and which partitions them into a specified number k of clusters. The algorithm attempts to find the centers of natural clusters in the data. The most common form of the algorithm starts by partitioning the input points into k initial sets, either at random or using some heuristic data. It then calculates the mean point, or centroid, of each set. It constructs a new partition by associating each point with the closest centroid. Then the centroids are recalculated for the new clusters, and the algorithm repeated by alternate applications of these two steps until convergence, which is obtained when the points no longer switch clusters (or alternatively centroids are no longer changed).
http://purl.obolibrary.org/obo/OBI_0200042	hierarchical clustering	http://purl.obolibrary.org/obo/OBI_0200175	class discovery data transformation		A hierarchical clustering is a data transformation which achieves a class discovery objective, which takes as input data item and builds a hierarchy of clusters. The traditional representation of this hierarchy is a tree (visualized by a dendrogram), with the individual input objects at one end (leaves) and a single cluster containing every object at the other (root).
http://purl.obolibrary.org/obo/OBI_0200078	descriptive statistical calculation objective	http://purl.obolibrary.org/obo/OBI_0200166	data transformation objective		A descriptive statistical calculation objective is a data transformation objective which concerns any calculation intended to describe a feature of a data set, for example, its center or its variability.
http://purl.obolibrary.org/obo/OBI_0200166	data transformation objective	http://purl.obolibrary.org/obo/IAO_0000005	objective specification		An objective specification to transformation input data into output data
http://purl.obolibrary.org/obo/OBI_0200170	averaging data transformation	http://purl.obolibrary.org/obo/OBI_0200000	data transformation		An averaging data transformation is a data transformation that has objective averaging.
http://purl.obolibrary.org/obo/OBI_0200171	partitioning data transformation	http://purl.obolibrary.org/obo/OBI_0200000	data transformation		A partitioning data transformation is a data transformation that has objective partitioning.
http://purl.obolibrary.org/obo/OBI_0200172	partitioning objective	http://purl.obolibrary.org/obo/OBI_0200166	data transformation objective		A partitioning objective is a data transformation objective where the aim is to generate a collection of disjoint non-empty subsets whose union equals a non-empty input set.
http://purl.obolibrary.org/obo/OBI_0200177	center calculation objective	http://purl.obolibrary.org/obo/OBI_0200166	data transformation objective		A center calculation objective is a data transformation objective where the aim is to calculate the center of an input data set.
http://purl.obolibrary.org/obo/OBI_0200181	center calculation data transformation	http://purl.obolibrary.org/obo/OBI_0200000	data transformation		A center calculation data transformation is a data transformation that has objective of center calculation.
http://purl.obolibrary.org/obo/OBI_0200184	descriptive statistical calculation data transformation	http://purl.obolibrary.org/obo/OBI_0200000	data transformation		A descriptive statistical calculation data transformation is a data transformation that has objective descriptive statistical calculation and which concerns any calculation intended to describe a feature of a data set, for example, its center or its variability.
http://purl.obolibrary.org/obo/OBI_0200190	clustered data visualization	http://purl.obolibrary.org/obo/OBI_0200111	data visualization		A data visualization which has input of a clustered data set and produces an output of a report graph which is capable of rendering data of this type.
http://purl.obolibrary.org/obo/OBI_0300311	observation design	http://purl.obolibrary.org/obo/OBI_0500000	study design		observation design is a study design in which subjects are monitored in the absence of any active intervention by experimentalists.
http://purl.obolibrary.org/obo/OBI_0500028	exclusion criterion	http://purl.obolibrary.org/obo/OBI_0500026	eligibility criterion		an exclusion criterion (rule) is_a *eligibility criterion*  which defines and states a condition which, if met, makes an entity unsuitable for a given task or participation in a given process. For instance, in a study protocol, exclusion criteria indicate the conditions that prospective subjects SHOULD NOT meet to be eligible for participation in a study
http://purl.obolibrary.org/obo/OBI_0600004	human subject enrollment	http://purl.obolibrary.org/obo/OBI_0001928	selection		A planned process with the objective to obtain a population of human subjects to participate in an investigation by determining eligibility of subjects and obtaining informed consent.
http://purl.obolibrary.org/obo/PATO_0001338	mixed sex	http://purl.obolibrary.org/obo/PATO_0002003	population quality		A biological sex quality inhering in a population of multiple sexes.
http://purl.obolibrary.org/obo/PATO_0001995	organismal quality	http://purl.obolibrary.org/obo/PATO_0001241	physical object characteristic		A quality that inheres in an entire organism or part of an organism.
http://purl.obolibrary.org/obo/OBCS_0000001	statistical data analysis	http://purl.obolibrary.org/obo/OBI_0200000	data transformation		A data transformation that has input of mulitple data and report overall trend of the data.
http://purl.obolibrary.org/obo/OBCS_0000002	data collection	http://purl.obolibrary.org/obo/OBI_0000011	obsolete planned process		A planned process that gathers and measures information on variables of interest, in an established systematic fashion that enables one to answer stated research questions, test hypotheses, and evaluate outcomes. Data collection results in a collection of data.
http://purl.obolibrary.org/obo/OBCS_0000010	probability distribution	http://purl.obolibrary.org/obo/IAO_0000030	information content entity		An information content entity that refers to a distribution of a random variable that can be described using a mathematical formula.
http://purl.obolibrary.org/obo/OBCS_0000013	test statistic	http://purl.obolibrary.org/obo/OBCS_0000220	derived data from inferential statistical analysis		A statistic measure that is a function of the samples and considered as a numberical summary of a data-set that reduces the data to one value that can be used to perform a hypothesis test. It can be used to test a finding for statistical signifiance
http://purl.obolibrary.org/obo/OBCS_0000068	frequency distribution	http://purl.obolibrary.org/obo/OBCS_0000010	probability distribution		A tabular summary of a set of data showing the number of items in each of several non-overlapping classes or groupings
http://purl.obolibrary.org/obo/OBCS_0000070	confidence interval	http://purl.obolibrary.org/obo/OBI_0000071	quantitative confidence value		A quantitative confidence value that refers to an interval give values within which there is a high probability (95 percent by convention) that the true population value can be found. The calculation of a confidence interval considers the standard deviation of the data and the number of observations. Thus, a confidence interval narrows as the number of observations increases, or its variance (dispersion) decreases.
http://purl.obolibrary.org/obo/OBCS_0000106	cohort study design	http://purl.obolibrary.org/obo/OBI_0500000	study design		A study design that starts with an exposure and moves forward to the outcome of interest, even if the data are collected retrospectively. As an example, a group of patients who have variable exposure to a risk factor of interest can be followed over time for an outcome.
http://purl.obolibrary.org/obo/OBCS_0000107	randomized controlled trial design	http://purl.obolibrary.org/obo/OBI_0500000	study design		A study design in which patients are randomly assigned to two or more interventions.
http://purl.obolibrary.org/obo/OBCS_0000123	transformed data set	http://purl.obolibrary.org/obo/OBCS_0000233	transformed data item		A data set that is produced as the output of a data transformation.
http://purl.obolibrary.org/obo/OBCS_0000124	inferential statistical data analysis objective	http://purl.obolibrary.org/obo/OBI_0200166	data transformation objective		A statistical data analysis objective where the aim is to make inference using population sample data. 
http://purl.obolibrary.org/obo/OBCS_0000127	data collection objective	http://purl.obolibrary.org/obo/IAO_0000005	objective specification		An objective specification where the aim is to collect data. 
http://purl.obolibrary.org/obo/OBCS_0000137	data collection design	http://purl.obolibrary.org/obo/IAO_0000104	plan specification		A plan specification that provides a detailed outline of how data is collected.
http://purl.obolibrary.org/obo/OBCS_0000233	transformed data item	http://purl.obolibrary.org/obo/IAO_0000027	data entity		A data item that is produced as the output of a data transformation.
http://purl.obolibrary.org/obo/STATO_0000166	bar chart	http://purl.obolibrary.org/obo/IAO_0000038	graph		the bart chart is a graph resulting from plotting rectangular bars with lengths proportional to the values that they represent.
http://semanticscience.org/resource/SIO_010060	family history	http://semanticscience.org/resource/SIO_001196	history		A medical history that records health-relevant conditions, events, or traits occurring in the biological relatives of a patient.
http://semanticscience.org/resource/SIO_010673	medical history	http://semanticscience.org/resource/SIO_001196	history		A medical history is a record of the events of a recipient of medical care.
http://purl.obolibrary.org/obo/SCDO_0000379	Diagnostics	http://purl.obolibrary.org/obo/SCDO_0001000	SCDO		Diagnostic tools (including the instruments, laboratory assays and methods of patient examination) used for differential diagnosis, the measurements obtained using these tools, and the diagnostic devices used in obtaining the measurements.
http://purl.obolibrary.org/obo/SCDO_0006339	Research	http://purl.obolibrary.org/obo/SCDO_0001000	SCDO		Critical and exhaustive investigation or experimentation, having for its aim the discovery of new facts and their correct interpretation, the revision of accepted conclusions, theories, or laws in the light of newly discovered facts, or the practical application of such new or revised conclusions, theories, or laws.
http://purl.obolibrary.org/obo/SCDO_1000849	acute clinical visit	http://purl.obolibrary.org/obo/NCIT_C103165	visit type		A clinical visit occuring because of an acute (severe with sudden onset) health condition.
http://purl.obolibrary.org/obo/SCDO_1000900	baseline visit	http://purl.obolibrary.org/obo/NCIT_C103165	visit type		A clinical visit that is the patient's first clinical visit.
http://purl.obolibrary.org/obo/SCDO_1000901	Follow-Up Visit	http://purl.obolibrary.org/obo/NCIT_C103165	visit type		A clinical visit that is a follow-up for a previous visit.
http://purl.obolibrary.org/obo/UBERON_0002405	immune system	http://purl.obolibrary.org/obo/UBERON_0015203	non-connected functional system		Anatomical system that protects the body from foreign substances, cells, and tissues by producing the immune response and that includes especially the thymus, spleen, lymphoid tissue, lymphocytes including the B cells and T cells, and antibodies.
http://purl.obolibrary.org/obo/UBERON_0000061	anatomical structure	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		Material anatomical entity that is a single connected structure with inherent 3D shape generated by coordinated expression of the organism's own genome.
http://purl.obolibrary.org/obo/UBERON_0000066	fully formed stage	http://purl.obolibrary.org/obo/UBERON_0000105	life cycle stage		The stage of development at which the animal is fully formed, including immaturity and maturity. Includes both sexually immature stage, and adult stage.
http://purl.obolibrary.org/obo/UBERON_0000068	embryo stage	http://purl.obolibrary.org/obo/UBERON_0000105	life cycle stage		A life cycle stage that starts with fertilization and ends with the fully formed embryo.
http://purl.obolibrary.org/obo/UBERON_0000071	death stage	http://purl.obolibrary.org/obo/UBERON_0000105	life cycle stage		End of the life of an organism.
http://purl.obolibrary.org/obo/UBERON_0000092	post-embryonic stage	http://purl.obolibrary.org/obo/UBERON_0000105	life cycle stage		Stage succeeding embryo, including mature structure.
http://purl.obolibrary.org/obo/UBERON_0000104	life cycle	http://purl.obolibrary.org/obo/BFO_0000015	process		An entire span of an organism's life. In metazoans, commences with the zygote stage and ends with the death of the organism.
http://purl.obolibrary.org/obo/UBERON_0000105	life cycle stage	http://purl.obolibrary.org/obo/BFO_0000015	process		A spatiotemporal region encompassing some part of the life cycle of an organism.
http://purl.obolibrary.org/obo/UBERON_0000111	organogenesis stage	http://purl.obolibrary.org/obo/UBERON_0000105	life cycle stage		A stage at which the ectoderm, endoderm, and mesoderm develop into the internal organs of the organism.
http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity	http://purl.obolibrary.org/obo/UBERON_0001062	anatomical entity		Anatomical entity that has mass.
http://purl.obolibrary.org/obo/UBERON_0000466	immaterial anatomical entity	http://purl.obolibrary.org/obo/UBERON_0001062	anatomical entity		Anatomical entity that has no mass.
http://purl.obolibrary.org/obo/UBERON_0000468	multicellular organism	http://purl.obolibrary.org/obo/UBERON_0010000	multicellular anatomical structure		Anatomical structure that is an individual member of a species and consists of more than one cell.
http://purl.obolibrary.org/obo/UBERON_0000477	anatomical cluster	http://purl.obolibrary.org/obo/UBERON_0034923	disconnected anatomical group		Anatomical group whose component anatomical structures lie in close proximity to each other.
http://purl.obolibrary.org/obo/UBERON_0010000	multicellular anatomical structure	http://purl.obolibrary.org/obo/UBERON_0000061	anatomical structure		An anatomical structure that has more than one cell as a part.
http://purl.obolibrary.org/obo/UBERON_0015203	non-connected functional system	http://purl.obolibrary.org/obo/UBERON_0034923	disconnected anatomical group		An anatomical group whose component structures share a common function.
http://purl.obolibrary.org/obo/UBERON_0034923	disconnected anatomical group	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		Material anatomical entity consisting of multiple anatomical structures that are not connected to each other.
http://purl.obolibrary.org/obo/OGMS_0000061	pathological bodily process	http://purl.obolibrary.org/obo/OGMS_0000060	bodily process		A bodily process that is clinically abnormal.
http://purl.obolibrary.org/obo/STATO_0000047	count	http://purl.obolibrary.org/obo/STATO_0000039	statistic		a count is a data item denoted by an integer and representing the number of instances or occurences of an entity
http://purl.obolibrary.org/obo/STATO_0000087	polychotomous variable	http://purl.obolibrary.org/obo/STATO_0000252	categorical variable		a polychotomous variable  is a categorical variable  which is defined to have minimally 2 categories or possible values
http://purl.obolibrary.org/obo/STATO_0000090	dichotomous variable	http://purl.obolibrary.org/obo/STATO_0000252	categorical variable		a dichotomous variable  is a categorical variable  which is defined to have only 2 categories or possible values
http://purl.obolibrary.org/obo/STATO_0000184	ratio	http://purl.obolibrary.org/obo/STATO_0000039	statistic		A ratio is a data item which is formed with two numbers r and s is written r/s, where r is the numerator and s is the denominator. The ratio of r to s is equivalent to the quotient r/s.
http://purl.obolibrary.org/obo/STATO_0000251	continuous variable	http://purl.obolibrary.org/obo/STATO_0000722	quantitative variable		A continuous variable is one for which, within the limits the variable ranges, any value is possible.
http://purl.obolibrary.org/obo/STATO_0000258	variable	http://purl.obolibrary.org/obo/STATO_0000741	statistical model component		A directive information entity that specifies a data item that can be measured or counted and is used in a statistical analysis.
http://www.ebi.ac.uk/efo/EFO_0001444	measurement	http://purl.obolibrary.org/obo/IAO_0000030	information content entity		A measurement is an information entity that is a recording of the output of a measurement such as produced by an instrument.
http://purl.obolibrary.org/obo/STATO_0000006	x-axis	http://purl.obolibrary.org/obo/STATO_0000011	cartesian coordinate axis		x-axis is a cartesian coordinate axis which is orthogonal to the y-axis and the z-axis
http://purl.obolibrary.org/obo/STATO_0000007	axis	http://purl.obolibrary.org/obo/IAO_0000573	line graph		an axis is a line graph used as reference line for the measurement of coordinates.
http://purl.obolibrary.org/obo/STATO_0000008	y-axis	http://purl.obolibrary.org/obo/STATO_0000011	cartesian coordinate axis		y-axis is a cartesian coordinate axis which is orthogonal to the x-axis and the z-axis
http://purl.obolibrary.org/obo/STATO_0000028	measure of dispersion	http://purl.obolibrary.org/obo/STATO_0000039	statistic		measure of variation or statistical dispersion is a data item which describes how much a theoritical distribution or dataset is spread.
http://purl.obolibrary.org/obo/STATO_0000029	measure of central tendency	http://purl.obolibrary.org/obo/STATO_0000039	statistic		a measure of central tendency is a data item which attempts to describe a set of data by identifying the value of its centre.
http://purl.obolibrary.org/obo/STATO_0000030	Chi-Squared statistic	http://purl.obolibrary.org/obo/STATO_0000609	measure of hypothesis testing		Chi-squared statistic is a statistic computed from observations and used to produce a p-value in statistical test when compared to a Chi-Squared distribution.
http://purl.obolibrary.org/obo/STATO_0000033	mode	http://purl.obolibrary.org/obo/STATO_0000574	center value		The mode is a data item which corresponds to the most frequently occurring number in a set of numbers.
http://purl.obolibrary.org/obo/STATO_0000039	statistic	http://purl.obolibrary.org/obo/IAO_0000027	data entity		a statistic is a measurement datum to describe a dataset or a variable. It is generated by a calculation on set of observed data.
http://purl.obolibrary.org/obo/STATO_0000068	skewness	http://purl.obolibrary.org/obo/STATO_0000039	statistic		Skewness is a data item indicating of the degree of asymmetry of a distribution.
http://purl.obolibrary.org/obo/STATO_0000088	study group population size	http://purl.obolibrary.org/obo/STATO_0000047	count		statistical sample size is a count evaluating the number of individual experimental units
http://purl.obolibrary.org/obo/STATO_0000152	quartile	http://purl.obolibrary.org/obo/STATO_0000291	quantile		a quartile is a quantile which splits data into sections accrued of 25% of data, so the first quartile delineates 25% of the data, the second quartile delineates 50% of the data and the third quartile, 75 % of the data
http://purl.obolibrary.org/obo/STATO_0000164	inter quartile range	http://purl.obolibrary.org/obo/STATO_0000028	measure of dispersion		The interquartile range is a data item which corresponds to the difference between the upper quartile (3rd quartile) and lower quartile (1st quartile).
The interquartile range contains the second quartile or median.
The interquartile range is a data item providing a measure of data dispersion.
http://purl.obolibrary.org/obo/STATO_0000167	first quartile	http://purl.obolibrary.org/obo/STATO_0000152	quartile		the first quartile is a quartile which splits the lower 25 % of the data
http://purl.obolibrary.org/obo/STATO_0000170	third quartile	http://purl.obolibrary.org/obo/STATO_0000152	quartile		the first quartile is a quartile which splits the 75 % of the data
http://purl.obolibrary.org/obo/STATO_0000178	kurtosis	http://purl.obolibrary.org/obo/STATO_0000039	statistic		Kurtosis is a data item which denotes the degree of peakedness of a distribution. It is defined as a normalized form of the fourth central moment of a distribution.
http://purl.obolibrary.org/obo/STATO_0000291	quantile	http://purl.obolibrary.org/obo/STATO_0000039	statistic		a quantile is a data item which corresponds to specific elements x in the range of a variate X.
the k-th n-tile P_k is that value of x, say x_k, which corresponds to a cumulative frequency of Nk/n (Kenney and Keeping 1962). If n=4, the quantity is called a quartile, and if n=100, it is called a percentile.
http://purl.obolibrary.org/obo/STATO_0000401	sample mean	http://purl.obolibrary.org/obo/STATO_0000573	average value		the sample mean of sample of size n with n observations is an arithmetic mean computed over n number of observations on a statistical sample.
The sample mean, denoted x¯ and read “x-bar,” is simply the average of the n data points x1, x2, ..., xn:

x¯=x1+x2+⋯+xnn=1n∑i=1nxi
The sample mean summarizes the "location" or "center" of the data.

the sample mean is a measure of dispersion of the observations made on the sample and provides an unbias estimate of the population mean
http://purl.obolibrary.org/obo/NCIT_C36291	Finding by Cause	http://purl.obolibrary.org/obo/NCIT_C3367	Finding		A term that refers to the classification of a clinical or laboratory finding according to the underlying factors.
http://purl.obolibrary.org/obo/COB_0000011	atom	http://purl.obolibrary.org/obo/BFO_0000040	material entity		A material entity consisting of exactly one atomic nucleus and the electron(s) orbiting it.
http://purl.obolibrary.org/obo/COB_0000013	molecule	http://purl.obolibrary.org/obo/BFO_0000040	material entity		A material entity that consists of two or more atoms that are all connected via covalent bonds such that any atom can be transitively connected with any other atom.
http://purl.obolibrary.org/obo/COB_0000021	gross anatomical part	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		A part of a multicellular organism that is a collection of cell components that are not all contained in one cell.
http://purl.obolibrary.org/obo/COB_0000022	organism	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		A material entity that is a maximal functionally integrated unit that develops from a program encoded in a genome
http://purl.obolibrary.org/obo/COB_0000026	processed material entity	http://purl.obolibrary.org/obo/BFO_0000040	material entity		A material entity processed by human activity with an intent to produce it.
http://purl.obolibrary.org/obo/COB_0000080	complex of molecules	http://purl.obolibrary.org/obo/BFO_0000040	material entity		A complex of two or more molecules that are not covalently bound.
http://purl.obolibrary.org/obo/COB_0000110	material processing	http://purl.obolibrary.org/obo/COB_0000035	completely executed planned process		A completely executed planned process that intends to output material entities from input material entities
http://purl.obolibrary.org/obo/DUO_0000042	general research use	http://purl.obolibrary.org/obo/DUO_0000001	data use permission		This data use permission indicates that use is allowed for general research use for any research purpose.
http://purl.obolibrary.org/obo/COB_0000082	planned process	http://purl.obolibrary.org/obo/BFO_0000015	process		A process that is initiated by an agent who intends to carry out a plan to achieve an objective through one or more actions as described in a plan specification.
http://purl.obolibrary.org/obo/DUO_0000004	no restriction	http://purl.obolibrary.org/obo/DUO_0000001	data use permission		This data use permission indicates there is no restriction on use.
http://purl.obolibrary.org/obo/DUO_0000006	health or medical or biomedical research	http://purl.obolibrary.org/obo/DUO_0000042	general research use		This data use permission indicates that use is allowed for health/medical/biomedical purposes; does not include the study of population origins or ancestry.
http://purl.obolibrary.org/obo/DUO_0000007	disease specific research	http://purl.obolibrary.org/obo/DUO_0000006	health or medical or biomedical research		This data use permission indicates that use is allowed provided it is related to the specified disease.
http://purl.obolibrary.org/obo/DUO_0000012	research specific restrictions	http://purl.obolibrary.org/obo/DUO_0000017	data use modifier		This data use modifier indicates that use is limited to studies of a certain research type.
http://purl.obolibrary.org/obo/DUO_0000015	no general methods research	http://purl.obolibrary.org/obo/DUO_0000017	data use modifier		This data use modifier indicates that use does not allow methods development research (e.g., development of software or algorithms).
http://purl.obolibrary.org/obo/DUO_0000016	genetic studies only	http://purl.obolibrary.org/obo/DUO_0000017	data use modifier		This data use modifier indicates that use is limited to genetic studies only (i.e., studies that include genotype research alone or both genotype and phenotype research, but not phenotype research exclusively)
http://purl.obolibrary.org/obo/DUO_0000017	data use modifier	http://purl.obolibrary.org/obo/IAO_0000027	data entity		Data use modifiers indicate additional conditions for use.
http://purl.obolibrary.org/obo/DUO_0000018	not for profit, non commercial use only	http://purl.obolibrary.org/obo/DUO_0000017	data use modifier		This data use modifier indicates that use of the data is limited to not-for-profit organizations and not-for-profit use, non-commercial use.
http://purl.obolibrary.org/obo/DUO_0000019	publication required	http://purl.obolibrary.org/obo/DUO_0000017	data use modifier		This data use modifier indicates that requestor agrees to make results of studies using the data available to the larger scientific community.
http://purl.obolibrary.org/obo/DUO_0000020	collaboration required	http://purl.obolibrary.org/obo/DUO_0000017	data use modifier		This data use modifier indicates that the requestor must agree to collaboration with the primary study investigator(s).
http://purl.obolibrary.org/obo/DUO_0000021	ethics approval required	http://purl.obolibrary.org/obo/DUO_0000017	data use modifier		This data use modifier indicates that the requestor must provide documentation of local IRB/ERB approval.
http://purl.obolibrary.org/obo/DUO_0000022	geographical restriction	http://purl.obolibrary.org/obo/DUO_0000017	data use modifier		This data use modifier indicates that use is limited to within a specific geographic region.
http://purl.obolibrary.org/obo/DUO_0000025	time limit on use	http://purl.obolibrary.org/obo/DUO_0000017	data use modifier		This data use modifier indicates that use is approved for a specific number of months.
http://purl.obolibrary.org/obo/DUO_0000026	user specific restriction	http://purl.obolibrary.org/obo/DUO_0000017	data use modifier		This data use modifier indicates that use is limited to use by approved users.
http://purl.obolibrary.org/obo/DUO_0000027	project specific restriction	http://purl.obolibrary.org/obo/DUO_0000017	data use modifier		This data use modifier indicates that use is limited to use within an approved project.
http://purl.obolibrary.org/obo/DUO_0000028	institution specific restriction	http://purl.obolibrary.org/obo/DUO_0000017	data use modifier		This data use modifier indicates that use is limited to use within an approved institution.
http://purl.obolibrary.org/obo/DUO_0000029	return to database or resource	http://purl.obolibrary.org/obo/DUO_0000017	data use modifier		This data use modifier indicates that the requestor must return derived/enriched data to the database/resource.
http://www.ebi.ac.uk/efo/EFO_0004302	anthropometric measurement	http://www.ebi.ac.uk/efo/EFO_0001444	measurement		Anthropometry is a measurement of the size, weight, and proportions of the human or other primate body.
http://purl.obolibrary.org/obo/OBI_0002453	health status inclusion criterion	http://purl.obolibrary.org/obo/OBI_0500027	inclusion criterion		An inclusion criterion that defines and states one or more clinically significant bodily components, dispositions, and/or bodily processes of an entity that are inferred from relevant clinical findings or self-reported, which, if met, makes the entity suitable for a given task or participation in a given process.
http://purl.obolibrary.org/obo/OBI_0002624	case-control study design	http://purl.obolibrary.org/obo/OBI_0500000	study design		A study design that entails the creation of two types of roles, such that each participant under investigation bears one or the other. What distinguishes the two types of roles is an 'outcome', which is associated with participants that have the case role but not associated with participants that have the control role. A case-control study examines the hypothesis that the presence of the outcome in case participants is associated with an 'exposure' that is not associated with control participants.
http://purl.obolibrary.org/obo/IAO_0000444	publishing process	http://purl.obolibrary.org/obo/COB_0000035	completely executed planned process		A planned process of making information, such as literature, music, and software etc., available to the public for sale or for free.
http://purl.obolibrary.org/obo/OBI_0003071	participant identifier	http://purl.obolibrary.org/obo/IAO_0000028	symbol		A symbol that denotes a participant under investigation.
http://purl.obolibrary.org/obo/STATO_0000609	measure of hypothesis testing	http://purl.obolibrary.org/obo/STATO_0000039	statistic		
http://purl.obolibrary.org/obo/NCIT_C3367	Finding	http://purl.obolibrary.org/obo/NCIT_C7057	Disease, Disorder or Finding		Clinical, laboratory or molecular evidence, or absence of evidence of disease.
http://purl.obolibrary.org/obo/NCIT_C62143	Encounter	http://purl.obolibrary.org/obo/NCIT_C25499	Event		Each individual, unique interaction between two subjects of interest.
http://purl.obolibrary.org/obo/NCIT_C103165	visit type	http://purl.obolibrary.org/obo/NCIT_C25284	Type		The kind of visit undertaken by the subject within a study, such as inpatient, outpatient, telephone, etc.
http://purl.obolibrary.org/obo/NCIT_C25284	Type	http://purl.obolibrary.org/obo/NCIT_C20189	Property or Attribute		Something distinguishable as an identifiable class based on common qualities.
http://purl.obolibrary.org/obo/NCIT_C25499	Event	http://purl.obolibrary.org/obo/NCIT_C20181	Conceptual Entity		Something that happens at a given place and time.
http://purl.obolibrary.org/obo/COB_0001300	device	http://purl.obolibrary.org/obo/COB_0000026	processed material entity		A processed material entity which is designed to be capable of a process.
http://purl.obolibrary.org/obo/OBI_0002205	histologic grade according to AJCC 7th edition	http://purl.obolibrary.org/obo/OBI_0001930	categorical value specification		A categorical value specification that is a histologic grade assigned to a tumor slide specimen according to the American Joint Committee on Cancer (AJCC) 7th Edition grading system.
http://purl.obolibrary.org/obo/OBI_0002215	histologic grade for ovarian tumor	http://purl.obolibrary.org/obo/OBI_0001930	categorical value specification		A categorical value specification that is a histologic grade assigned to a ovarian tumor.
http://purl.obolibrary.org/obo/OBI_0002216	histologic grade for ovarian tumor according to a two-tier grading system	http://purl.obolibrary.org/obo/OBI_0002215	histologic grade for ovarian tumor		A histologic grade for ovarian tumor that is from a two-tier histological classification of tumors.
http://purl.obolibrary.org/obo/OBI_0002219	histologic grade for ovarian tumor according to the World Health Organization	http://purl.obolibrary.org/obo/OBI_0002215	histologic grade for ovarian tumor		A histologic grade for ovarian tumor that is from a histological classification by the World Health Organization (WHO).
http://purl.obolibrary.org/obo/STATO_0000471	estimate	http://purl.obolibrary.org/obo/STATO_0000039	statistic		a estimate is a data item which is computed from a dataset to provide an approximated value (an estimator) for a 'statistical parameter'  (a 'characteristics/parameter' of the true underlying distribution) of a real population.
http://purl.obolibrary.org/obo/STATO_0000573	average value	http://purl.obolibrary.org/obo/STATO_0000029	measure of central tendency		The arithmetic mean is defined as the sum of the numerical values of each and every observation divided by the total number of observations. S The arithmetic mean A is defined by the formula

A=sum[Ai] / n where i ranges from 1 to n and Ai represents the value of individual observations.

The arithmetic mean is significantly affected by extreme values and outliers. A better measure of central tendency is the median (http://purl.obolibrary.org/obo/STATO_0000574).
http://purl.obolibrary.org/obo/DUO_00000044	population origins or ancestry research prohibited	http://purl.obolibrary.org/obo/DUO_0000017	data use modifier		This data use modifier indicates use for purposes of population, origin, or ancestry research is prohibited.
http://purl.obolibrary.org/obo/DUO_0000043	clinical care use	http://purl.obolibrary.org/obo/DUO_0000017	data use modifier		This data use modifier indicates that use is allowed for clinical use and care.
http://purl.obolibrary.org/obo/DUO_0000045	not for profit organisation use only	http://purl.obolibrary.org/obo/DUO_0000018	not for profit, non commercial use only		This data use modifier indicates that use of the data is limited to not-for-profit organizations.
http://purl.obolibrary.org/obo/DUO_0000046	non-commercial use only	http://purl.obolibrary.org/obo/DUO_0000018	not for profit, non commercial use only		This data use modifier indicates that use of the data is limited to not-for-profit use.
http://purl.obolibrary.org/obo/OBI_0002989	material supplier	http://purl.obolibrary.org/obo/BFO_0000040	material entity		A person or organization that provides material supplies to other people or organizations.
http://purl.obolibrary.org/obo/SCDO_0000728	Diagnostic Measurement	http://purl.obolibrary.org/obo/SCDO_0000379	Diagnostics		An information entity used in the diagnosis of medical conditions. It could be the recording of the output of a diagnostic device or the outcome of a diagnostic tool.
http://purl.obolibrary.org/obo/NCIT_C53781	Adverse Event by CTCAE Category	http://purl.obolibrary.org/obo/NCIT_C208323	CTCAE Adverse Events Version 3.0		An adverse event as categorized by the Common Terminology Criteria for Adverse Events (CTCAE).
http://purl.obolibrary.org/obo/NCIT_C154624	Healthcare Encounter	http://purl.obolibrary.org/obo/NCIT_C62143	Encounter		Interactions between patients and providers within the context of healthcare delivery.
http://purl.obolibrary.org/obo/OGMS_0000123	clinical data item	http://purl.obolibrary.org/obo/IAO_0000027	data entity		A data item that is about a patient and is the specified output of a health care process assay or diagnostic process
http://purl.obolibrary.org/obo/CTO_0000033	healthy volunteer criterion	http://purl.obolibrary.org/obo/OBI_0500027	inclusion criterion		Indication that participants who do not have a disease or condition, or related conditions or symptoms, under study in the clinical study are permitted to participate in the clinical study.
http://purl.obolibrary.org/obo/OAE_0000095	causal adverse drug event	http://purl.obolibrary.org/obo/OAE_0000005	adverse drug event		
http://purl.obolibrary.org/obo/BFO_0000141	immaterial entity	http://purl.obolibrary.org/obo/BFO_0000004	independent continuant		
http://purl.obolibrary.org/obo/OGMS_0000060	bodily process	http://purl.obolibrary.org/obo/BFO_0000015	process		
http://purl.obolibrary.org/obo/BFO_0000034	function	http://purl.obolibrary.org/obo/BFO_0000016	disposition		
http://purl.obolibrary.org/obo/BFO_0000016	disposition	http://purl.obolibrary.org/obo/BFO_0000017	realizable entity		
http://purl.obolibrary.org/obo/BFO_0000019	quality	http://purl.obolibrary.org/obo/BFO_0000020	specifically dependent continuant		
http://purl.obolibrary.org/obo/BFO_0000006	spatial region	http://purl.obolibrary.org/obo/BFO_0000141	immaterial entity		
http://purl.obolibrary.org/obo/BFO_0000029	site	http://purl.obolibrary.org/obo/BFO_0000141	immaterial entity		
http://purl.obolibrary.org/obo/STATO_0000741	statistical model component	http://purl.obolibrary.org/obo/IAO_0000027	data entity		
http://purl.obolibrary.org/obo/IAO_0000429	email address	http://purl.obolibrary.org/obo/IAO_0000030	information content entity		
http://purl.obolibrary.org/obo/IAO_0000582	time stamped measurement datum	http://purl.obolibrary.org/obo/IAO_0000109	measurement datum		
http://semanticscience.org/resource/SIO_000006	process	http://semanticscience.org/resource/SIO_000000	entity		
http://semanticscience.org/resource/SIO_000614	attribute	http://semanticscience.org/resource/SIO_000000	entity		
http://semanticscience.org/resource/SIO_000776	object	http://semanticscience.org/resource/SIO_000000	entity		
http://semanticscience.org/resource/SIO_000027	process quality	http://semanticscience.org/resource/SIO_000005	quality		
http://semanticscience.org/resource/SIO_000075	mathematical entity	http://semanticscience.org/resource/SIO_000015	information content entity		
http://semanticscience.org/resource/SIO_000078	language entity	http://semanticscience.org/resource/SIO_000015	information content entity		
http://semanticscience.org/resource/SIO_000676	social role	http://semanticscience.org/resource/SIO_000016	role		
http://semanticscience.org/resource/SIO_000033	process status	http://semanticscience.org/resource/SIO_000027	process quality		
http://semanticscience.org/resource/SIO_000035	ongoing	http://semanticscience.org/resource/SIO_000033	process status		
http://semanticscience.org/resource/SIO_000074	unit of measurement	http://semanticscience.org/resource/SIO_000052	quantity		
http://semanticscience.org/resource/SIO_000257	dimensionless quantity	http://semanticscience.org/resource/SIO_000052	quantity		
http://semanticscience.org/resource/SIO_000258	dimensional quantity	http://semanticscience.org/resource/SIO_000052	quantity		
http://semanticscience.org/resource/SIO_001108	centrality measure	http://semanticscience.org/resource/SIO_000052	quantity		
http://semanticscience.org/resource/SIO_000052	quantity	http://semanticscience.org/resource/SIO_000070	measurement value		
http://semanticscience.org/resource/SIO_001429	tensor	http://semanticscience.org/resource/SIO_000075	mathematical entity		
http://semanticscience.org/resource/SIO_000108	character	http://semanticscience.org/resource/SIO_000078	language entity		
http://semanticscience.org/resource/SIO_000114	word	http://semanticscience.org/resource/SIO_000078	language entity		
http://semanticscience.org/resource/SIO_000275	term	http://semanticscience.org/resource/SIO_000078	language entity		
http://semanticscience.org/resource/SIO_000483	phrase	http://semanticscience.org/resource/SIO_000078	language entity		
http://semanticscience.org/resource/SIO_001040	morpheme	http://semanticscience.org/resource/SIO_000078	language entity		
http://semanticscience.org/resource/SIO_000136	description	http://semanticscience.org/resource/SIO_000078	language entity		
http://semanticscience.org/resource/SIO_000133	descriptor	http://semanticscience.org/resource/SIO_000275	term		
http://semanticscience.org/resource/SIO_000016	role	http://semanticscience.org/resource/SIO_000340	realizable entity		
http://semanticscience.org/resource/SIO_000005	quality	http://semanticscience.org/resource/SIO_000614	attribute		
http://semanticscience.org/resource/SIO_000340	realizable entity	http://semanticscience.org/resource/SIO_000614	attribute		
http://semanticscience.org/resource/SIO_000706	occupational role	http://semanticscience.org/resource/SIO_000676	social role		
http://semanticscience.org/resource/SIO_000726	administrative role	http://semanticscience.org/resource/SIO_000706	occupational role		
http://semanticscience.org/resource/SIO_000015	information content entity	http://semanticscience.org/resource/SIO_000776	object		
http://semanticscience.org/resource/SIO_001353	specialized object	http://semanticscience.org/resource/SIO_000776	object		
http://semanticscience.org/resource/SIO_001110	median	http://semanticscience.org/resource/SIO_001108	centrality measure		
http://purl.obolibrary.org/obo/NCBITaxon_131567	cellular organisms	http://purl.obolibrary.org/obo/NCBITaxon_1	root		
http://purl.obolibrary.org/obo/NCBITaxon_117571	Euteleostomi	http://purl.obolibrary.org/obo/NCBITaxon_117570	Teleostomi		
http://purl.obolibrary.org/obo/NCBITaxon_8287	Sarcopterygii	http://purl.obolibrary.org/obo/NCBITaxon_117571	Euteleostomi		
http://purl.obolibrary.org/obo/NCBITaxon_2759	Eukaryota	http://purl.obolibrary.org/obo/NCBITaxon_131567	cellular organisms		
http://purl.obolibrary.org/obo/NCBITaxon_32523	Tetrapoda	http://purl.obolibrary.org/obo/NCBITaxon_1338369	Dipnotetrapodomorpha		
http://purl.obolibrary.org/obo/NCBITaxon_314146	Euarchontoglires	http://purl.obolibrary.org/obo/NCBITaxon_1437010	Boreoeutheria		
http://purl.obolibrary.org/obo/NCBITaxon_33090	Viridiplantae	http://purl.obolibrary.org/obo/NCBITaxon_2759	Eukaryota		
http://purl.obolibrary.org/obo/NCBITaxon_33154	Opisthokonta	http://purl.obolibrary.org/obo/NCBITaxon_2759	Eukaryota		
http://purl.obolibrary.org/obo/NCBITaxon_9443	Primates	http://purl.obolibrary.org/obo/NCBITaxon_314146	Euarchontoglires		
http://purl.obolibrary.org/obo/NCBITaxon_32524	Amniota	http://purl.obolibrary.org/obo/NCBITaxon_32523	Tetrapoda		
http://purl.obolibrary.org/obo/NCBITaxon_40674	Mammalia	http://purl.obolibrary.org/obo/NCBITaxon_32524	Amniota		
http://purl.obolibrary.org/obo/NCBITaxon_9347	Eutheria	http://purl.obolibrary.org/obo/NCBITaxon_32525	Theria <mammals>		
http://purl.obolibrary.org/obo/NCBITaxon_4751	Fungi	http://purl.obolibrary.org/obo/NCBITaxon_33154	Opisthokonta		
http://purl.obolibrary.org/obo/NCBITaxon_33208	Metazoa	http://purl.obolibrary.org/obo/NCBITaxon_33154	Opisthokonta		
http://purl.obolibrary.org/obo/NCBITaxon_6072	Eumetazoa	http://purl.obolibrary.org/obo/NCBITaxon_33208	Metazoa		
http://purl.obolibrary.org/obo/NCBITaxon_33511	Deuterostomia	http://purl.obolibrary.org/obo/NCBITaxon_33213	Bilateria		
http://purl.obolibrary.org/obo/NCBITaxon_7711	Chordata	http://purl.obolibrary.org/obo/NCBITaxon_33511	Deuterostomia		
http://purl.obolibrary.org/obo/NCBITaxon_32525	Theria <mammals>	http://purl.obolibrary.org/obo/NCBITaxon_40674	Mammalia		
http://purl.obolibrary.org/obo/NCBITaxon_33213	Bilateria	http://purl.obolibrary.org/obo/NCBITaxon_6072	Eumetazoa		
http://purl.obolibrary.org/obo/NCBITaxon_89593	Craniata <chordates>	http://purl.obolibrary.org/obo/NCBITaxon_7711	Chordata		
http://purl.obolibrary.org/obo/NCBITaxon_7776	Gnathostomata <vertebrates>	http://purl.obolibrary.org/obo/NCBITaxon_7742	Vertebrata <vertebrates>		
http://purl.obolibrary.org/obo/NCBITaxon_117570	Teleostomi	http://purl.obolibrary.org/obo/NCBITaxon_7776	Gnathostomata <vertebrates>		
http://purl.obolibrary.org/obo/NCBITaxon_1338369	Dipnotetrapodomorpha	http://purl.obolibrary.org/obo/NCBITaxon_8287	Sarcopterygii		
http://purl.obolibrary.org/obo/NCBITaxon_7742	Vertebrata <vertebrates>	http://purl.obolibrary.org/obo/NCBITaxon_89593	Craniata <chordates>		
http://purl.obolibrary.org/obo/NCBITaxon_1437010	Boreoeutheria	http://purl.obolibrary.org/obo/NCBITaxon_9347	Eutheria		
http://semanticscience.org/resource/SIO_001196	history	http://semanticscience.org/resource/SIO_000136	description		
http://purl.obolibrary.org/obo/COB_0000035	completely executed planned process	http://purl.obolibrary.org/obo/COB_0000082	planned process		
http://semanticscience.org/resource/SIO_001431	scalar	http://semanticscience.org/resource/SIO_001429	tensor		
http://semanticscience.org/resource/SIO_000366	number	http://semanticscience.org/resource/SIO_001431	scalar		
http://semanticscience.org/resource/SIO_000070	measurement value	http://semanticscience.org/resource/SIO_000366	number		
http://purl.obolibrary.org/obo/NCBITaxon_9605	Homo	http://purl.obolibrary.org/obo/NCBITaxon_207598	Homininae		
http://purl.obolibrary.org/obo/NCBITaxon_9526	Catarrhini	http://purl.obolibrary.org/obo/NCBITaxon_314293	Simiiformes		
http://purl.obolibrary.org/obo/NCBITaxon_9604	Hominidae	http://purl.obolibrary.org/obo/NCBITaxon_314295	Hominoidea		
http://purl.obolibrary.org/obo/NCBITaxon_314293	Simiiformes	http://purl.obolibrary.org/obo/NCBITaxon_376913	Haplorrhini		
http://purl.obolibrary.org/obo/NCBITaxon_376913	Haplorrhini	http://purl.obolibrary.org/obo/NCBITaxon_9443	Primates		
http://purl.obolibrary.org/obo/NCBITaxon_314295	Hominoidea	http://purl.obolibrary.org/obo/NCBITaxon_9526	Catarrhini		
http://purl.obolibrary.org/obo/NCBITaxon_207598	Homininae	http://purl.obolibrary.org/obo/NCBITaxon_9604	Hominidae		
http://purl.obolibrary.org/obo/NCBITaxon_9606	Homo sapiens	http://purl.obolibrary.org/obo/NCBITaxon_9605	Homo		
http://purl.obolibrary.org/obo/NCIT_C53782	Adverse Event Associated with Allergy and Immunology	http://purl.obolibrary.org/obo/NCIT_C53781	Adverse Event by CTCAE Category		
http://purl.obolibrary.org/obo/SCDO_0001000	SCDO				Root of all terms in the Sickle Cell Disease Ontology, an effort of unambiguously describing all concepts and unifying up-to-date knowledge in sickle cell disease.
http://purl.obolibrary.org/obo/PATO_0000001	characteristic				The properties, attributes, or modifiers used to describe an entity or process or some aspect of an entity or process.
http://www.ebi.ac.uk/efo/EFO_0000001	experimental factor				An experimental factor in Array Express which are essentially the variable aspects of an experiment design which can be used to describe an experiment, or set of experiments, in an increasingly detailed manner. This upper level class is really used to give a root class from which applications can rely on and not be tied to upper ontology classses which do change.
http://purl.obolibrary.org/obo/NCIT_C20047	Diagnostic or Prognostic Factor				A characteristic of an organism that contributes to the diagnosis or treatment of a disease or to the prediction of clinical outcomes.
http://purl.obolibrary.org/obo/NCIT_C7057	Disease, Disorder or Finding				A condition that is relevant to human neoplasms and non-neoplastic disorders.  This includes observations, test results, history and other concepts relevant to the characterization of human pathologic conditions.
http://purl.obolibrary.org/obo/OBI_0000011	obsolete planned process				A process that realizes a plan which is the concretization of a plan specification.
http://purl.obolibrary.org/obo/UBERON_0001062	anatomical entity				Biological entity that is either an individual member of a biological species or constitutes the structural organization of an individual member of a biological species.
http://purl.obolibrary.org/obo/SYMP_0000462	symptom				A symptom is a perceived change in function, sensation, loss, disturbance or appearance reported by a patient indicative of a disease.
http://purl.obolibrary.org/obo/NCIT_C20181	Conceptual Entity				An organizational header for concepts representing mostly abstract entities.
http://purl.obolibrary.org/obo/NCIT_C20189	Property or Attribute				A distinguishing quality or prominent aspect of a person, object, action, process, or substance.
http://purl.obolibrary.org/obo/CMEO_0000031	obsolete anthropometric measurement				
http://purl.obolibrary.org/obo/CMEO_0000041	obsolete medical history				
http://purl.obolibrary.org/obo/CMEO_0000042	obsolete family history				
http://purl.obolibrary.org/obo/CMEO_0000057	obsolete symptom				
http://purl.obolibrary.org/obo/CMEO_0000068	obsolete healthy volunteer criterion				
http://purl.obolibrary.org/obo/BFO_0000001	entity				
http://semanticscience.org/resource/SIO_000000	entity				
http://purl.obolibrary.org/obo/NCBITaxon_1	root				
http://purl.obolibrary.org/obo/COB_0000502	characteristic				
http://purl.obolibrary.org/obo/OAE_0000025	induced_by	http://purl.obolibrary.org/obo/BFO_0000062	preceded by	induced by	a preceded_by relation that indicates that one process (e.g., an adverse event) is causally preceded by (induced by) another process (e.g., a medical intervention) and there is a causal relation between these two processes. This relation indicates the existence of a causal chain, meaning many processes may occur in between these two processes.
http://purl.obolibrary.org/obo/OAE_0002081	AE occurs in	http://purl.obolibrary.org/obo/BFO_0000066	occurs in	adverse event occurs in	a 'occurs in' relation that is applied at the adverse event setting and indicates where an adverse event occurs in.
http://purl.obolibrary.org/obo/RO_0002234	has output	http://purl.obolibrary.org/obo/RO_0000057	has participant	produces	p has output c iff c is a participant in p, c is present at the end of p, and c is not present in the same state at the beginning of p.
http://purl.obolibrary.org/obo/RO_0000052	characteristic of	http://purl.obolibrary.org/obo/RO_0002314	characteristic of part of	inheres_in	a relation between a specifically dependent continuant (the characteristic) and any other entity (the bearer), in which the characteristic depends on the bearer for its existence.
http://purl.obolibrary.org/obo/RO_0000079	function of	http://purl.obolibrary.org/obo/RO_0000052	characteristic of	is function of	a relation between a function and an independent continuant (the bearer), in which the function specifically depends on the bearer for its existence
http://purl.obolibrary.org/obo/RO_0000080	quality of	http://purl.obolibrary.org/obo/RO_0000052	characteristic of	quality_of	a relation between a quality and an independent continuant (the bearer), in which the quality specifically depends on the bearer for its existence
http://purl.obolibrary.org/obo/RO_0000085	has function	http://purl.obolibrary.org/obo/RO_0000053	has characteristic	has_function	a relation between an independent continuant (the bearer) and a function, in which the function specifically depends on the bearer for its existence
http://purl.obolibrary.org/obo/RO_0000086	has quality	http://purl.obolibrary.org/obo/RO_0000053	has characteristic	has_quality	a relation between an independent continuant (the bearer) and a quality, in which the quality specifically depends on the bearer for its existence
http://purl.obolibrary.org/obo/RO_0002350	member of	http://purl.obolibrary.org/obo/BFO_0000050	part of	member part of	is member of is a mereological relation between a item and a collection.
http://purl.obolibrary.org/obo/BFO_0000051	has part	http://purl.obolibrary.org/obo/RO_0002131	overlaps	has_part	a core relation that holds between a whole and its part
http://purl.obolibrary.org/obo/RO_0000087	has role	http://purl.obolibrary.org/obo/RO_0000053	has characteristic	has_role	a relation between an independent continuant (the bearer) and a role, in which the role specifically depends on the bearer for its existence
http://purl.obolibrary.org/obo/RO_0002327	enables	http://purl.obolibrary.org/obo/RO_0002215	capable of	is executing	c enables p iff c is capable of p and c acts to execute p.
http://purl.obolibrary.org/obo/RO_0002409	indirectly negatively regulates	http://purl.obolibrary.org/obo/RO_0012012	indirectly regulates	indirectly inhibits	p indirectly negatively regulates q iff p is indirectly causally upstream of q and p negatively regulates q.
http://purl.obolibrary.org/obo/RO_0002436	molecularly interacts with	http://purl.obolibrary.org/obo/RO_0002434	interacts with	molecularly binds with	An interaction relationship in which the two partners are molecular entities that directly physically interact with each other for example via a stable binding interaction or a brief interaction during which one modifies the other.
http://purl.obolibrary.org/obo/RO_0002449	directly negatively regulates activity of	http://purl.obolibrary.org/obo/RO_0002448	directly regulates activity of	directly inhibits	The entity A, immediately upstream of the entity B, has an activity that negatively regulates an activity performed by B. 
For example, A and B may be gene products and binding of B by A negatively regulates the kinase activity of B.
http://purl.obolibrary.org/obo/BFO_0000062	preceded by	http://purl.obolibrary.org/obo/RO_0002086	ends after	preceded_by	x is preceded by y if and only if the time point at which y ends is before or equivalent to the time point at which x starts. Formally: x preceded by y iff ω(y) <= α(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point.
http://purl.obolibrary.org/obo/RO_0000081	role of	http://purl.obolibrary.org/obo/RO_0000052	characteristic of	role_of	a relation between a role and an independent continuant (the bearer), in which the role specifically depends on the bearer for its existence
http://purl.obolibrary.org/obo/BFO_0000050	part of	http://purl.obolibrary.org/obo/RO_0002131	overlaps	part_of	a core relation that holds between a part and its whole
http://purl.obolibrary.org/obo/RO_0002233	has input	http://purl.obolibrary.org/obo/RO_0000057	has participant	consumes	p has input c iff: p is a process, c is a material entity, c is a participant in p, c is present at the start of p, and the state of c is modified during p.
http://purl.obolibrary.org/obo/RO_0002314	characteristic of part of	http://purl.obolibrary.org/obo/RO_0002502	depends on	inheres in part of	q characteristic of part of w if and only if there exists some p such that q inheres in p and p part of w.
http://purl.obolibrary.org/obo/RO_0002215	capable of	http://purl.obolibrary.org/obo/RO_0002216	capable of part of	has function realized in	A relation between a material entity (such as a cell) and a process, in which the material entity has the ability to carry out the process. 
http://purl.obolibrary.org/obo/RO_0002331	involved in	http://purl.obolibrary.org/obo/RO_0002431	involved in or involved in regulation of	enables part of	c involved_in p if and only if c enables some process p', and p' is part of p
http://purl.obolibrary.org/obo/RO_0002431	involved in or involved in regulation of	http://purl.obolibrary.org/obo/RO_0002500	causal agent in process	involved in or reguates	c involved in or regulates p if and only if either (i) c is involved in p or (ii) c is involved in regulation of p
http://purl.obolibrary.org/obo/RO_0002216	capable of part of	http://purl.obolibrary.org/obo/RO_0002500	causal agent in process	has function in	c stands in this relationship to p if and only if there exists some p' such that c is capable_of p', and p' is part_of p.
http://purl.obolibrary.org/obo/RO_0002329	part of structure that is capable of	http://purl.obolibrary.org/obo/RO_0002328	functionally related to	0	this relation holds between c and p when c is part of some c', and c' is capable of p.
http://purl.obolibrary.org/obo/RO_0002418	causally upstream of or within	http://purl.obolibrary.org/obo/RO_0002501	causal relation between processes	influences (processual)	p is 'causally upstream or within' q iff p is causally related to q, and the end of p precedes, or is coincident with, the end of q.
http://purl.obolibrary.org/obo/RO_0002230	ends with	http://purl.obolibrary.org/obo/RO_0002222	temporally related to	finished by	x ends with y if and only if x has part y and the time point at which x ends is equivalent to the time point at which y ends. Formally: α(y) > α(x) ∧ ω(y) = ω(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point.
http://purl.obolibrary.org/obo/RO_0002232	has end location	http://purl.obolibrary.org/obo/RO_0002479	has part that occurs in	ends with process that occurs in	x 'has end location' y if and only if there exists some process z such that x 'ends with' z and z 'occurs in' y
http://purl.obolibrary.org/obo/RO_0002407	indirectly positively regulates	http://purl.obolibrary.org/obo/RO_0012012	indirectly regulates	indirectly activates	p indirectly positively regulates q iff p is indirectly causally upstream of q and p positively regulates q.
http://purl.obolibrary.org/obo/RO_0002413	provides input for	http://purl.obolibrary.org/obo/RO_0002414	transitively provides input for	directly provides input for	p provides input for q iff p is immediately causally upstream of q, and there exists some c such that p has_output c and q has_input c.
http://purl.obolibrary.org/obo/RO_0002432	is active in	http://purl.obolibrary.org/obo/RO_0002328	functionally related to	executes activity in	c executes activity in d if and only if c enables p and p occurs_in d.  Assuming no action at a distance by gene products, if a gene product enables (is capable of) a process that occurs in some structure, it must have at least some part in that structure.
http://purl.obolibrary.org/obo/RO_0002450	directly positively regulates activity of	http://purl.obolibrary.org/obo/RO_0002448	directly regulates activity of	directly activates	The entity A, immediately upstream of the entity B, has an activity that positively regulates an activity performed by B. 
For example, A and B may be gene products and binding of B by A positively regulates the kinase activity of B.
http://purl.obolibrary.org/obo/RO_0004028	realized in response to stimulus	http://purl.obolibrary.org/obo/RO_0002410	causally related to		A relationship between a realizable entity R (e.g. function or disposition) and a material entity M where R is realized in response to a process that has an input stimulus of M.
http://purl.obolibrary.org/obo/RO_0002025	has effector activity	http://purl.obolibrary.org/obo/RO_0002017	has component activity		A 'has effector activity' B if A and B are GO molecular functions (GO_0003674),  A 'has component activity' B and B is the effector (output function) of B.  Each compound function has only one effector activity.
http://purl.obolibrary.org/obo/RO_0002162	in taxon	http://purl.obolibrary.org/obo/RO_0002320	evolutionarily related to		x is in taxon y if an only if y is an organism, and the relationship between x and y is one of: part of (reflexive), developmentally preceded by, derives from, secreted by, expressed.
http://purl.obolibrary.org/obo/CMEO_0000084	is record of	http://purl.obolibrary.org/obo/IAO_0000136	is about		Relates an information content entity (a record or variable) to the occurrent (e.g. a process or event) whose occurrence it documents. A more specific form of 'is about' for records of occurrents.
http://purl.obolibrary.org/obo/BFO_0000063	precedes	http://purl.obolibrary.org/obo/RO_0002222	temporally related to		x precedes y if and only if the time point at which x ends is before or equivalent to the time point at which y starts. Formally: x precedes y iff ω(x) <= α(y), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point.
http://purl.obolibrary.org/obo/IAO_0000219	denotes	http://purl.obolibrary.org/obo/IAO_0000136	is about		A primitive, instance-level, relation obtaining between an information content entity and some portion of reality. Denotation is what happens when someone creates an information content entity E in order to specifically refer to something. The only relation between E and the thing is that E can be used to 'pick out' the thing. This relation connects those two together. Freedictionary.com sense 3: To signify directly; refer to specifically
http://purl.obolibrary.org/obo/IAO_0000221	is quality measurement of	http://purl.obolibrary.org/obo/IAO_0000136	is about		m is a quality measurement of q at t. When q is a quality, there is a measurement process p that has specified output m, a measurement datum, that is about q
http://purl.obolibrary.org/obo/IAO_0000413	is duration of	http://purl.obolibrary.org/obo/IAO_0000136	is about		relates a process to a time-measurement-datum that represents the duration of the process
http://purl.obolibrary.org/obo/IAO_0000581	has time stamp	http://purl.obolibrary.org/obo/BFO_0000051	has part		relates a time stamped measurement datum to the time measurement datum that denotes the time when the measurement was taken
http://purl.obolibrary.org/obo/IAO_0000583	has measurement datum	http://purl.obolibrary.org/obo/BFO_0000051	has part		relates a time stamped measurement datum to the measurement datum that was measured
http://purl.obolibrary.org/obo/OBI_0000293	has specified input	http://purl.obolibrary.org/obo/RO_0000057	has participant		The inverse property of is specified input of
http://purl.obolibrary.org/obo/OBI_0000295	is specified input of	http://purl.obolibrary.org/obo/RO_0000056	participates in		A relation between a completely executed planned process and a continuant participating in that process that is not created during the process. The presence of the continuant during the process is explicitly specified in the plan specification which the process realizes the concretization of.
http://purl.obolibrary.org/obo/OBI_0000299	has specified output	http://purl.obolibrary.org/obo/RO_0000057	has participant		The inverse property of is specified output of
http://purl.obolibrary.org/obo/OBI_0000312	is specified output of	http://purl.obolibrary.org/obo/RO_0000056	participates in		A relation between a completely executed planned process and a continuant participating in that process. The presence of the continuant at the end of the process is explicitly specified in the objective specification which the process realizes the concretization of.
http://purl.obolibrary.org/obo/OBI_0001927	specifies value of	http://purl.obolibrary.org/obo/IAO_0000136	is about		A relation between a value specification and an entity which the specification is about.
http://purl.obolibrary.org/obo/OBI_0001938	has value specification	http://purl.obolibrary.org/obo/BFO_0000051	has part		A relation between an information content entity and a value specification that specifies its value.
http://purl.obolibrary.org/obo/RO_0002351	has member	http://purl.obolibrary.org/obo/BFO_0000051	has part		has member is a mereological relation between a collection and an item.
http://purl.obolibrary.org/obo/RO_0002018	has component process	http://purl.obolibrary.org/obo/RO_0002180	has component		w 'has process component' p if p and w are processes,  w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type.
http://purl.obolibrary.org/obo/RO_0019000	regulates characteristic	http://purl.obolibrary.org/obo/RO_0002410	causally related to		A relationship that holds between a process and a characteristic in which process (P) regulates characteristic (C) iff: P results in the existence of C OR affects the intensity or magnitude of C.
http://purl.obolibrary.org/obo/RO_0019001	positively regulates characteristic	http://purl.obolibrary.org/obo/RO_0019000	regulates characteristic		A relationship that holds between a process and a characteristic in which process (P) positively regulates characteristic (C) iff: P results in an increase in the intensity or magnitude of C.
http://purl.obolibrary.org/obo/RO_0019002	negatively regulates characteristic	http://purl.obolibrary.org/obo/RO_0019000	regulates characteristic		A relationship that holds between a process and a characteristic in which process (P) negatively regulates characteristic (C) iff: P results in a decrease in the intensity or magnitude of C.
http://purl.obolibrary.org/obo/RO_0002333	enabled by	http://purl.obolibrary.org/obo/RO_0002328	functionally related to		inverse of enables
http://purl.obolibrary.org/obo/RO_0002404	causally downstream of	http://purl.obolibrary.org/obo/RO_0002427	causally downstream of or within		inverse of upstream of
http://purl.obolibrary.org/obo/RO_0002412	immediately causally upstream of	http://purl.obolibrary.org/obo/RO_0002411	causally upstream of		p is immediately causally upstream of q iff p is causally upstream of q, and the end of p is coincident with the beginning of q.
http://purl.obolibrary.org/obo/RO_0002448	directly regulates activity of	http://purl.obolibrary.org/obo/RO_0011002	regulates activity of		The entity A, immediately upstream of the entity B, has an activity that regulates an activity performed by B. For example, A and B may be gene products and binding of B by A regulates the kinase activity of B.

A and B can be physically interacting but not necessarily. Immediately upstream means there are no intermediate entity between A and B.
http://purl.obolibrary.org/obo/RO_0002566	causally influences	http://purl.obolibrary.org/obo/RO_0002506	causal relation between entities		The entity or characteristic A is causally upstream of the entity or characteristic B, A having an effect on B. An entity corresponds to any biological type of entity as long as a mass is measurable. A characteristic corresponds to a particular specificity of an entity (e.g., phenotype, shape, size).
http://purl.obolibrary.org/obo/RO_0002490	existence overlaps	http://purl.obolibrary.org/obo/RO_0002487	relation between physical entity and a process or stage		x existence overlaps y if and only if either (a) the start of x is part of y or (b) the end of x is part of y. Formally: x existence starts and ends during y iff (α(x) >= α(y) & α(x) <= ω(y)) OR (ω(x) <= ω(y) & ω(x) >= α(y))
http://purl.obolibrary.org/obo/RO_0002263	acts upstream of	http://purl.obolibrary.org/obo/RO_0002264	acts upstream of or within		c acts upstream of p if and only if c enables some f that is involved in p' and p' occurs chronologically before p, is not part of p, and affects the execution of p. c is a material entity and f, p, p' are processes.
http://purl.obolibrary.org/obo/RO_0002304	causally upstream of, positive effect	http://purl.obolibrary.org/obo/RO_0004047	causally upstream of or within, positive effect		p is causally upstream of, positive effect q iff p is casually upstream of q, and the execution of p is required for the execution of q.
http://purl.obolibrary.org/obo/RO_0002305	causally upstream of, negative effect	http://purl.obolibrary.org/obo/RO_0004046	causally upstream of or within, negative effect		p is causally upstream of, negative effect q iff p is casually upstream of q, and the execution of p decreases the execution of q.
http://purl.obolibrary.org/obo/RO_0002131	overlaps	http://purl.obolibrary.org/obo/RO_0002323	mereotopologically related to		x overlaps y if and only if there exists some z such that x has part z and z part of y
http://purl.obolibrary.org/obo/RO_0002497	existence ends during or before	http://purl.obolibrary.org/obo/RO_0002487	relation between physical entity and a process or stage		x existence ends during or before y if and only if the time point at which x ends is before or equivalent to the time point at which y ends.
http://purl.obolibrary.org/obo/RO_0000091	has disposition	http://purl.obolibrary.org/obo/RO_0000053	has characteristic		a relation between an independent continuant (the bearer) and a disposition, in which the disposition specifically depends on the bearer for its existence
http://purl.obolibrary.org/obo/RO_0000092	disposition of	http://purl.obolibrary.org/obo/RO_0000052	characteristic of		inverse of has disposition
http://purl.obolibrary.org/obo/RO_0011002	regulates activity of	http://purl.obolibrary.org/obo/RO_0002566	causally influences		The entity A has an activity that regulates an activity of the entity B. For example, A and B are gene products where the catalytic activity of A regulates the kinase activity of B.
http://purl.obolibrary.org/obo/RO_0002411	causally upstream of	http://purl.obolibrary.org/obo/RO_0002418	causally upstream of or within		p is causally upstream of q iff p is causally related to q, the end of p precedes the end of q, and p is not an occurrent part of q.
http://purl.obolibrary.org/obo/RO_0002211	regulates	http://purl.obolibrary.org/obo/RO_0002411	causally upstream of		p regulates q iff p is causally upstream of q, the execution of p is not constant and varies according to specific conditions, and p influences the rate or magnitude of execution of q due to an effect either on some enabler of q or some enabler of a part of q.
http://purl.obolibrary.org/obo/RO_0002212	negatively regulates	http://purl.obolibrary.org/obo/RO_0002211	regulates		p negatively regulates q iff p regulates q, and p decreases the rate or magnitude of execution of q.
http://purl.obolibrary.org/obo/RO_0002213	positively regulates	http://purl.obolibrary.org/obo/RO_0002211	regulates		p positively regulates q iff p regulates q, and p increases the rate or magnitude of execution of q.
http://purl.obolibrary.org/obo/RO_0002180	has component	http://purl.obolibrary.org/obo/BFO_0000051	has part		w 'has component' p if w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type.
http://purl.obolibrary.org/obo/RO_0002352	input of	http://purl.obolibrary.org/obo/RO_0002328	functionally related to		inverse of has input
http://purl.obolibrary.org/obo/RO_0002353	output of	http://purl.obolibrary.org/obo/RO_0002328	functionally related to		inverse of has output
http://purl.obolibrary.org/obo/RO_0002473	composed primarily of	http://purl.obolibrary.org/obo/BFO_0000051	has part		x composed_primarily_of y if and only if more than half of the mass of x is made from y or units of the same type as y.
http://purl.obolibrary.org/obo/RO_0002023	directly negatively regulated by	http://purl.obolibrary.org/obo/RO_0002022	directly regulated by		Process(P2) is directly negatively regulated by process(P1) iff: P1 negatively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2).  For example, if protein A has protein binding activity(P1) that targets protein B and this binding  negatively regulates the kinase activity (P2) of protein B then P2 directly negatively regulated by P1.
http://purl.obolibrary.org/obo/RO_0002024	directly positively regulated by	http://purl.obolibrary.org/obo/RO_0002022	directly regulated by		Process(P2) is directly postively regulated by process(P1) iff: P1 positively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2).  For example, if protein A has protein binding activity(P1) that targets protein B and this binding positively regulates the kinase activity (P2) of protein B then P2 is directly postively regulated by P1.
http://purl.obolibrary.org/obo/RO_0012011	indirectly causally upstream of	http://purl.obolibrary.org/obo/RO_0002411	causally upstream of		p is indirectly causally upstream of q iff p is causally upstream of q and there exists some process r such that p is causally upstream of r and r is causally upstream of q.
http://purl.obolibrary.org/obo/RO_0012012	indirectly regulates	http://purl.obolibrary.org/obo/RO_0012011	indirectly causally upstream of		p indirectly regulates q iff p is indirectly causally upstream of q and p regulates q.
http://purl.obolibrary.org/obo/RO_0002264	acts upstream of or within	http://purl.obolibrary.org/obo/RO_0002500	causal agent in process		c acts upstream of or within p if c is enables f, and f is causally upstream of or within p. c is a material entity and p is an process.
http://purl.obolibrary.org/obo/RO_0002492	existence ends during	http://purl.obolibrary.org/obo/RO_0002497	existence ends during or before		x existence ends during y if and only if the time point at which x ends is before or equivalent to the time point at which y ends and after or equivalent to the point at which y starts. Formally: x existence ends during y iff ω(x) <= ω(y) and ω(x) >= α(y).
http://purl.obolibrary.org/obo/RO_0004031	enables subfunction	http://purl.obolibrary.org/obo/RO_0002328	functionally related to		Holds between an entity and an process P where the entity enables some larger compound process, and that larger process has-part P.
http://purl.obolibrary.org/obo/RO_0004034	acts upstream of, positive effect	http://purl.obolibrary.org/obo/RO_0004032	acts upstream of or within, positive effect		c 'acts upstream of, positive effect' p if c is enables f, and f is causally upstream of p, and the direction of f is positive
http://purl.obolibrary.org/obo/RO_0004035	acts upstream of, negative effect	http://purl.obolibrary.org/obo/RO_0004033	acts upstream of or within, negative effect		c 'acts upstream of, negative effect' p if c is enables f, and f is causally upstream of p, and the direction of f is negative
http://purl.obolibrary.org/obo/RO_0019009	component of	http://purl.obolibrary.org/obo/BFO_0000050	part of		Inverse of 'has component'.
http://purl.obolibrary.org/obo/RO_0002334	regulated by	http://purl.obolibrary.org/obo/RO_0002427	causally downstream of or within		inverse of regulates
http://purl.obolibrary.org/obo/RO_0002335	negatively regulated by	http://purl.obolibrary.org/obo/RO_0002334	regulated by		inverse of negatively regulates
http://purl.obolibrary.org/obo/RO_0002336	positively regulated by	http://purl.obolibrary.org/obo/RO_0002334	regulated by		inverse of positively regulates
http://purl.obolibrary.org/obo/RO_0002379	spatially coextensive with	http://purl.obolibrary.org/obo/RO_0002131	overlaps		x spatially_coextensive_with y if and inly if x and y have the same location
http://purl.obolibrary.org/obo/RO_0002427	causally downstream of or within	http://purl.obolibrary.org/obo/RO_0002501	causal relation between processes		inverse of causally upstream of or within
http://purl.obolibrary.org/obo/RO_0002500	causal agent in process	http://purl.obolibrary.org/obo/RO_0002595	causal relation between material entity and a process		A relationship between a material entity and a process where the material entity has some causal role that influences the process
http://purl.obolibrary.org/obo/RO_0002501	causal relation between processes	http://purl.obolibrary.org/obo/RO_0002410	causally related to		p is causally related to q if and only if p or any part of p and q or any part of q are linked by a chain of events where each event pair is one where the execution of p influences the execution of q. p may be upstream, downstream, part of, or a container of q.
http://purl.obolibrary.org/obo/RO_0002584	has part structure that is capable of	http://purl.obolibrary.org/obo/RO_0002595	causal relation between material entity and a process		s 'has part structure that is capable of' p if and only if there exists some part x such that s 'has part' x and x 'capable of' p
http://purl.obolibrary.org/obo/RO_0002595	causal relation between material entity and a process	http://purl.obolibrary.org/obo/RO_0002410	causally related to		A relationship that holds between a material entity and a process in which causality is involved, with either the material entity or some part of the material entity exerting some influence over the process, or the process influencing some aspect of the material entity.
http://purl.obolibrary.org/obo/RO_0002596	capable of regulating	http://purl.obolibrary.org/obo/RO_0002500	causal agent in process		Holds between c and p if and only if c is capable of some activity a, and a regulates p.
http://purl.obolibrary.org/obo/RO_0002597	capable of negatively regulating	http://purl.obolibrary.org/obo/RO_0002596	capable of regulating		Holds between c and p if and only if c is capable of some activity a, and a negatively regulates p.
http://purl.obolibrary.org/obo/RO_0002598	capable of positively regulating	http://purl.obolibrary.org/obo/RO_0002596	capable of regulating		Holds between c and p if and only if c is capable of some activity a, and a positively regulates p.
http://purl.obolibrary.org/obo/RO_0002608	process has causal agent	http://purl.obolibrary.org/obo/RO_0002410	causally related to		Inverse of 'causal agent in process'
http://purl.obolibrary.org/obo/RO_0002015	has positive regulatory component activity	http://purl.obolibrary.org/obo/RO_0002013	has regulatory component activity		A relationship that holds between a GO molecular function and a component of that molecular function that positively regulates the activity of the whole.  More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is positively regulated by B.
http://purl.obolibrary.org/obo/RO_0002013	has regulatory component activity	http://purl.obolibrary.org/obo/RO_0002017	has component activity		A 'has regulatory component activity' B if A and B are GO molecular functions (GO_0003674), A has_component B and A is regulated by B.
http://purl.obolibrary.org/obo/RO_0002014	has negative regulatory component activity	http://purl.obolibrary.org/obo/RO_0002013	has regulatory component activity		A relationship that holds between a GO molecular function and a component of that molecular function that negatively regulates the activity of the whole.  More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is negatively regulated by B.
http://purl.obolibrary.org/obo/RO_0002082	simultaneous with	http://purl.obolibrary.org/obo/RO_0002081	before or simultaneous with		x simultaneous with y iff ω(x) = ω(y) and ω(α ) = ω(α), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point and '=' indicates the same instance in time.
http://purl.obolibrary.org/obo/RO_0002229	ends	http://purl.obolibrary.org/obo/BFO_0000050	part of		inverse of ends with
http://purl.obolibrary.org/obo/RO_0009501	realized in response to	http://purl.obolibrary.org/obo/RO_0002410	causally related to		r 'realized in response to' s iff, r is a realizable (e.g. a plant trait such as responsivity to drought), s is an environmental stimulus (a process), and s directly causes the realization of r.
http://purl.obolibrary.org/obo/RO_0002414	transitively provides input for	http://purl.obolibrary.org/obo/RO_0004047	causally upstream of or within, positive effect		transitive form of directly_provides_input_for
http://purl.obolibrary.org/obo/RO_0002428	involved in regulation of	http://purl.obolibrary.org/obo/RO_0002431	involved in or involved in regulation of		c involved in regulation of p if c is involved in some p' and p' regulates some p
http://purl.obolibrary.org/obo/RO_0002429	involved in positive regulation of	http://purl.obolibrary.org/obo/RO_0002428	involved in regulation of		c involved in regulation of p if c is involved in some p' and p' positively regulates some p
http://purl.obolibrary.org/obo/RO_0002430	involved in negative regulation of	http://purl.obolibrary.org/obo/RO_0002428	involved in regulation of		c involved in regulation of p if c is involved in some p' and p' negatively regulates some p
http://purl.obolibrary.org/obo/RO_0002578	directly regulates	http://purl.obolibrary.org/obo/RO_0002211	regulates		p directly regulates q iff p is immediately causally upstream of q and p regulates q.
http://purl.obolibrary.org/obo/RO_0002629	directly positively regulates	http://purl.obolibrary.org/obo/RO_0002578	directly regulates		p directly positively regulates q iff p is immediately causally upstream of q, and p positively regulates q.
http://purl.obolibrary.org/obo/RO_0002630	directly negatively regulates	http://purl.obolibrary.org/obo/RO_0002578	directly regulates		p directly negatively regulates q iff p is immediately causally upstream of q, and p negatively regulates q.
http://purl.obolibrary.org/obo/RO_0002081	before or simultaneous with	http://purl.obolibrary.org/obo/RO_0002222	temporally related to	<=	
http://purl.obolibrary.org/obo/RO_0002087	immediately preceded by	http://purl.obolibrary.org/obo/BFO_0000062	preceded by	starts_at_end_of	
http://purl.obolibrary.org/obo/RO_0002090	immediately precedes	http://purl.obolibrary.org/obo/BFO_0000063	precedes	meets	
http://purl.obolibrary.org/obo/RO_0002447	phosphorylates	http://purl.obolibrary.org/obo/RO_0002436	molecularly interacts with	An interaction relation between x and y in which x catalyzes a reaction in which a phosphate group is added to y.	
http://purl.obolibrary.org/obo/RO_0002405	immediately causally downstream of	http://purl.obolibrary.org/obo/RO_0002404	causally downstream of		
http://semanticscience.org/resource/SIO_000053	has proper part	http://semanticscience.org/resource/SIO_000028	has part		
http://semanticscience.org/resource/SIO_000273	has direct part	http://semanticscience.org/resource/SIO_000053	has proper part		
http://semanticscience.org/resource/SIO_000068	is part of	http://semanticscience.org/resource/SIO_000061	is located in		
http://semanticscience.org/resource/SIO_000093	is proper part of	http://semanticscience.org/resource/SIO_000068	is part of		
http://semanticscience.org/resource/SIO_000310	is direct part of	http://semanticscience.org/resource/SIO_000093	is proper part of		
http://semanticscience.org/resource/SIO_000028	has part	http://semanticscience.org/resource/SIO_000145	is location of		
http://semanticscience.org/resource/SIO_000217	has quality	http://semanticscience.org/resource/SIO_000223	has property		
http://semanticscience.org/resource/SIO_000644	has realizable property	http://semanticscience.org/resource/SIO_000223	has property		
http://semanticscience.org/resource/SIO_000218	is quality of	http://semanticscience.org/resource/SIO_000224	is property of		
http://semanticscience.org/resource/SIO_000643	is realizable property of	http://semanticscience.org/resource/SIO_000224	is property of		
http://semanticscience.org/resource/SIO_000061	is located in	http://semanticscience.org/resource/SIO_000322	is spatiotemporally related to		
http://semanticscience.org/resource/SIO_000145	is location of	http://semanticscience.org/resource/SIO_000322	is spatiotemporally related to		
http://semanticscience.org/resource/SIO_000325	overlaps with	http://semanticscience.org/resource/SIO_000322	is spatiotemporally related to		
http://purl.obolibrary.org/obo/RO_0002017	has component activity	http://purl.obolibrary.org/obo/RO_0002018	has component process		
http://purl.obolibrary.org/obo/IAO_0000039	has measurement unit label	http://purl.obolibrary.org/obo/BFO_0000051	has part		
http://purl.obolibrary.org/obo/RO_0002559	causally influenced by	http://purl.obolibrary.org/obo/RO_0002506	causal relation between entities		
http://purl.obolibrary.org/obo/RO_0002563	interaction relation helper property	http://purl.obolibrary.org/obo/RO_0002464	helper property (not for use in curation)		
http://purl.obolibrary.org/obo/RO_0002564	molecular interaction relation helper property	http://purl.obolibrary.org/obo/RO_0002563	interaction relation helper property		
http://purl.obolibrary.org/obo/RO_0002481	is kinase activity	http://purl.obolibrary.org/obo/RO_0002564	molecular interaction relation helper property		
http://purl.obolibrary.org/obo/RO_0002086	ends after	http://purl.obolibrary.org/obo/RO_0002222	temporally related to		
http://purl.obolibrary.org/obo/RO_0004033	acts upstream of or within, negative effect	http://purl.obolibrary.org/obo/RO_0002264	acts upstream of or within		
http://purl.obolibrary.org/obo/RO_0004032	acts upstream of or within, positive effect	http://purl.obolibrary.org/obo/RO_0002264	acts upstream of or within		
http://purl.obolibrary.org/obo/RO_0002022	directly regulated by	http://purl.obolibrary.org/obo/RO_0002334	regulated by		
http://purl.obolibrary.org/obo/RO_0002506	causal relation between entities	http://purl.obolibrary.org/obo/RO_0002410	causally related to		
http://purl.obolibrary.org/obo/RO_0004046	causally upstream of or within, negative effect	http://purl.obolibrary.org/obo/RO_0002418	causally upstream of or within		
http://purl.obolibrary.org/obo/RO_0004047	causally upstream of or within, positive effect	http://purl.obolibrary.org/obo/RO_0002418	causally upstream of or within		
http://semanticscience.org/resource/SIO_000216	has measurement value	http://semanticscience.org/resource/SIO_000008	has attribute		
http://semanticscience.org/resource/SIO_000221	has unit	http://semanticscience.org/resource/SIO_000008	has attribute		
http://semanticscience.org/resource/SIO_000223	has property	http://semanticscience.org/resource/SIO_000008	has attribute		
http://semanticscience.org/resource/SIO_000255	has annotation	http://semanticscience.org/resource/SIO_000008	has attribute		
http://semanticscience.org/resource/SIO_000322	is spatiotemporally related to	http://semanticscience.org/resource/SIO_000001	is related to		
http://semanticscience.org/resource/SIO_000008	has attribute	http://semanticscience.org/resource/SIO_000001	is related to		
http://semanticscience.org/resource/SIO_000011	is attribute of	http://semanticscience.org/resource/SIO_000001	is related to		
http://semanticscience.org/resource/SIO_000215	is measurement value of	http://semanticscience.org/resource/SIO_000011	is attribute of		
http://semanticscience.org/resource/SIO_000222	is unit of	http://semanticscience.org/resource/SIO_000011	is attribute of		
http://semanticscience.org/resource/SIO_000224	is property of	http://semanticscience.org/resource/SIO_000011	is attribute of		
http://semanticscience.org/resource/SIO_000254	is annotation of	http://semanticscience.org/resource/SIO_000011	is attribute of		
http://purl.obolibrary.org/obo/RO_0000053	has characteristic			is bearer of	Inverse of characteristic_of
http://purl.obolibrary.org/obo/RO_0000056	participates in			participates_in	a relation between a continuant and a process, in which the continuant is somehow involved in the process
http://purl.obolibrary.org/obo/RO_0000057	has participant			has_participant	a relation between a process and a continuant, in which the continuant is somehow involved in the process
http://purl.obolibrary.org/obo/RO_0001015	location of			location_of	a relation between two independent continuants, the location and the target, in which the target is entirely within the location
http://purl.obolibrary.org/obo/RO_0001025	located in			located_in	a relation between two independent continuants, the target and the location, in which the target is entirely within the location
http://purl.obolibrary.org/obo/BFO_0000066	occurs in			unfolds_in	b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t
http://purl.obolibrary.org/obo/OAE_0001788	has participant quality				an object property that represents a relation between a process and a quality, in which the process has a participant that has the quality.
http://purl.obolibrary.org/obo/RO_0002320	evolutionarily related to				A relationship that holds via some environmental process
http://purl.obolibrary.org/obo/BFO_0000055	realizes				Paraphrase of elucidation: a relation between a process and a realizable entity, where there is some material entity that is bearer of the realizable entity and participates in the process, and the realizable entity comes to be realized in the course of the process
http://purl.obolibrary.org/obo/BFO_0000067	contains process				[copied from inverse property 'occurs in'] b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t
http://purl.obolibrary.org/obo/IAO_0000136	is about				A (currently) primitive relation that relates an information artifact to an entity.
http://purl.obolibrary.org/obo/IAO_0000417	is quality measured as				inverse of the relation of is quality measurement of
http://purl.obolibrary.org/obo/OBI_0000124	is_supported_by_data				The relation between a data item and a conclusion where the conclusion is the output of a data interpreting process and the data item is used as an input to that process
http://purl.obolibrary.org/obo/OBI_0000417	achieves_planned_objective				This relation obtains between a planned process and a objective specification when the criteria specified in the objective specification are met at the end of the planned process.
http://purl.obolibrary.org/obo/OBI_0000833	objective_achieved_by				This relation obtains between an objective specification and a planned process when the criteria specified in the objective specification are met at the end of the planned process.
http://purl.obolibrary.org/obo/RO_0000058	is concretized as				A relationship between a generically dependent continuant and a specifically dependent continuant or process, in which the generically dependent continuant depends on some independent continuant or process in virtue of the fact that the specifically dependent continuant or process also depends on that same independent continuant. A generically dependent continuant may be concretized as multiple specifically dependent continuants or processes.
http://purl.obolibrary.org/obo/RO_0000059	concretizes				A relationship between a specifically dependent continuant or process and a generically dependent continuant, in which the generically dependent continuant depends on some independent continuant in virtue of the fact that the specifically dependent continuant or process also depends on that same independent continuant. Multiple specifically dependent continuants or processes can concretize the same generically dependent continuant.
http://purl.obolibrary.org/obo/RO_0017001	device utilizes material				X device utilizes material Y means X and Y are material entities, and X is capable of some process P that has input Y.
http://purl.obolibrary.org/obo/RO_0003000	produces				a produces b if some process that occurs_in a has_output b, where a and b are material entities. Examples: hybridoma cell line produces monoclonal antibody reagent; chondroblast produces avascular GAG-rich matrix.
http://purl.obolibrary.org/obo/RO_0003001	produced by				a produced_by b iff some process that occurs_in b has_output a.
http://purl.obolibrary.org/obo/RO_0002434	interacts with				A relationship that holds between two entities in which the processes executed by the two entities are causally connected.
http://purl.obolibrary.org/obo/STATO_0000129	has value				A relationship (data property) between an entity and its value.
http://purl.obolibrary.org/obo/RO_0002323	mereotopologically related to				A mereological relationship or a topological relationship
http://purl.obolibrary.org/obo/RO_0002328	functionally related to				A grouping relationship for any relationship directly involving a function, or that holds because of a function of one of the related entities.
http://purl.obolibrary.org/obo/RO_0020105	is anatomical entity				This property only applies to anatomical entities.
http://purl.obolibrary.org/obo/DUO_0000010	is restricted to				A is restricted to B iff A is a consent code and B is an investigation and A may only participate in instances of a class C, of which B is an instance.
http://purl.obolibrary.org/obo/IAO_0000235	denoted by				inverse of the relation 'denotes'
http://purl.obolibrary.org/obo/RO_0002410	causally related to				relation that links two events, processes, states, or objects such that one event, process, state, or object (a cause) contributes to the production of another event, process, state, or object (an effect) where the cause is partly or wholly responsible for the effect, and the effect is partly or wholly dependent on the cause.
http://purl.obolibrary.org/obo/RO_0002479	has part that occurs in				p has part that occurs in c if and only if there exists some p1, such that p has_part p1, and p1 occurs in c.
http://purl.obolibrary.org/obo/RO_0010001	generically depends on				A generically dependent continuant *b* generically depends on an independent continuant *c* at time *t* means: there inheres in *c* a specifically deendent continuant which concretizes *b* at *t*.
http://purl.obolibrary.org/obo/RO_0010002	is carrier of				*b* is carrier of *c* at time *t* if and only if *c* *g-depends on* *b* at *t*
http://purl.obolibrary.org/obo/BFO_0000054	realized in			realized_in	
http://purl.obolibrary.org/obo/CMEO_0000082	obsolete has value				
http://purl.obolibrary.org/obo/IAO_0000004	has measurement value				
http://semanticscience.org/resource/SIO_000300	has value				
http://purl.obolibrary.org/obo/RO_0002464	helper property (not for use in curation)				
http://purl.obolibrary.org/obo/RO_0002487	relation between physical entity and a process or stage				
http://purl.obolibrary.org/obo/RO_0002222	temporally related to				
http://purl.obolibrary.org/obo/RO_0002502	depends on				
http://semanticscience.org/resource/SIO_000001	is related to