Term IRI	Term label	Parent term IRI	Parent term label	Alternative term	Definition
http://purl.obolibrary.org/obo/RO_0000052	characteristic of	http://purl.obolibrary.org/obo/RO_0002314	characteristic of part of	inheres_in	a relation between a specifically dependent continuant (the characteristic) and any other entity (the bearer), in which the characteristic depends on the bearer for its existence.
http://purl.obolibrary.org/obo/RO_0000079	function of	http://purl.obolibrary.org/obo/RO_0000052	characteristic of	is function of	a relation between a function and an independent continuant (the bearer), in which the function specifically depends on the bearer for its existence
http://purl.obolibrary.org/obo/RO_0000080	quality of	http://purl.obolibrary.org/obo/RO_0000052	characteristic of	quality_of	a relation between a quality and an independent continuant (the bearer), in which the quality specifically depends on the bearer for its existence
http://purl.obolibrary.org/obo/RO_0000085	has function	http://purl.obolibrary.org/obo/RO_0000053	has characteristic	has_function	a relation between an independent continuant (the bearer) and a function, in which the function specifically depends on the bearer for its existence
http://purl.obolibrary.org/obo/RO_0000086	has quality	http://purl.obolibrary.org/obo/RO_0000053	has characteristic	has_quality	a relation between an independent continuant (the bearer) and a quality, in which the quality specifically depends on the bearer for its existence
http://purl.obolibrary.org/obo/BFO_0000051	has_part	http://purl.obolibrary.org/obo/RO_0002131	location of	has_part	a core relation that holds between a whole and its part
http://purl.obolibrary.org/obo/RO_0000087	has role	http://purl.obolibrary.org/obo/RO_0000053	has characteristic	has_role	a relation between an independent continuant (the bearer) and a role, in which the role specifically depends on the bearer for its existence
http://purl.obolibrary.org/obo/RO_0002327	enables	http://purl.obolibrary.org/obo/RO_0002215	capable of	is executing	c enables p iff c is capable of p and c acts to execute p.
http://purl.obolibrary.org/obo/RO_0002409	indirectly negatively regulates	http://purl.obolibrary.org/obo/RO_0012012	indirectly regulates	indirectly inhibits	p indirectly negatively regulates q iff p is indirectly causally upstream of q and p negatively regulates q.
http://purl.obolibrary.org/obo/RO_0002436	molecularly interacts with	http://purl.obolibrary.org/obo/RO_0002434	interacts with	molecularly binds with	An interaction relationship in which the two partners are molecular entities that directly physically interact with each other for example via a stable binding interaction or a brief interaction during which one modifies the other.
http://purl.obolibrary.org/obo/RO_0002449	directly negatively regulates activity of	http://purl.obolibrary.org/obo/RO_0002448	directly regulates activity of	directly inhibits	The entity A, immediately upstream of the entity B, has an activity that negatively regulates an activity performed by B. 
For example, A and B may be gene products and binding of B by A negatively regulates the kinase activity of B.
http://purl.obolibrary.org/obo/BFO_0000062	preceded by	http://purl.obolibrary.org/obo/RO_0002086	ends after	preceded_by	x is preceded by y if and only if the time point at which y ends is before or equivalent to the time point at which x starts. Formally: x preceded by y iff ω(y) <= α(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point.
http://purl.obolibrary.org/obo/RO_0000081	role of	http://purl.obolibrary.org/obo/RO_0000052	characteristic of	role_of	a relation between a role and an independent continuant (the bearer), in which the role specifically depends on the bearer for its existence
http://purl.obolibrary.org/obo/BFO_0000050	part_of	http://purl.obolibrary.org/obo/RO_0002131	location of	part_of	a core relation that holds between a part and its whole
http://purl.obolibrary.org/obo/RO_0002233	has input	http://purl.obolibrary.org/obo/RO_0000057	has participant	consumes	p has input c iff: p is a process, c is a material entity, c is a participant in p, c is present at the start of p, and the state of c is modified during p.
http://purl.obolibrary.org/obo/RO_0002314	characteristic of part of	http://purl.obolibrary.org/obo/RO_0002502	depends on	inheres in part of	q characteristic of part of w if and only if there exists some p such that q inheres in p and p part of w.
http://purl.obolibrary.org/obo/RO_0002215	capable of	http://purl.obolibrary.org/obo/RO_0002216	capable of part of	has function realized in	A relation between a material entity (such as a cell) and a process, in which the material entity has the ability to carry out the process. 
http://purl.obolibrary.org/obo/RO_0002331	involved in	http://purl.obolibrary.org/obo/RO_0002431	involved in or involved in regulation of	enables part of	c involved_in p if and only if c enables some process p', and p' is part of p
http://purl.obolibrary.org/obo/RO_0002431	involved in or involved in regulation of	http://purl.obolibrary.org/obo/RO_0002500	causal agent in process	involved in or reguates	c involved in or regulates p if and only if either (i) c is involved in p or (ii) c is involved in regulation of p
http://purl.obolibrary.org/obo/RO_0002216	capable of part of	http://purl.obolibrary.org/obo/RO_0002500	causal agent in process	has function in	c stands in this relationship to p if and only if there exists some p' such that c is capable_of p', and p' is part_of p.
http://purl.obolibrary.org/obo/RO_0002329	part of structure that is capable of	http://purl.obolibrary.org/obo/RO_0002328	functionally related to	0	this relation holds between c and p when c is part of some c', and c' is capable of p.
http://purl.obolibrary.org/obo/RO_0002418	causally upstream of or within	http://purl.obolibrary.org/obo/RO_0002501	causal relation between processes	influences (processual)	p is 'causally upstream or within' q iff p is causally related to q, and the end of p precedes, or is coincident with, the end of q.
http://purl.obolibrary.org/obo/RO_0002407	indirectly positively regulates	http://purl.obolibrary.org/obo/RO_0012012	indirectly regulates	indirectly activates	p indirectly positively regulates q iff p is indirectly causally upstream of q and p positively regulates q.
http://purl.obolibrary.org/obo/RO_0002450	directly positively regulates activity of	http://purl.obolibrary.org/obo/RO_0002448	directly regulates activity of	directly activates	The entity A, immediately upstream of the entity B, has an activity that positively regulates an activity performed by B. 
For example, A and B may be gene products and binding of B by A positively regulates the kinase activity of B.
http://purl.obolibrary.org/obo/RO_0004028	realized in response to stimulus	http://purl.obolibrary.org/obo/RO_0002410	causally related to		A relationship between a realizable entity R (e.g. function or disposition) and a material entity M where R is realized in response to a process that has an input stimulus of M.
http://purl.obolibrary.org/obo/RO_0002025	has effector activity	http://purl.obolibrary.org/obo/RO_0002017	has component activity		A 'has effector activity' B if A and B are GO molecular functions (GO_0003674),  A 'has component activity' B and B is the effector (output function) of B.  Each compound function has only one effector activity.
http://purl.obolibrary.org/obo/BFO_0000063	precedes	http://purl.obolibrary.org/obo/RO_0002222	temporally related to		x precedes y if and only if the time point at which x ends is before or equivalent to the time point at which y starts. Formally: x precedes y iff ω(x) <= α(y), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point.
http://purl.obolibrary.org/obo/OBI_0000643	has grain	http://purl.obolibrary.org/obo/BFO_0000051	has_part		the relation of the cells in the finger of the skin to the finger, in which an indeterminate number of grains are parts of the whole by virtue of being grains in a collective that is part of the whole, and in which removing one granular part does not nec- essarily damage or diminish the whole. Ontological Whether there is a fixed, or nearly fixed number of parts - e.g. fingers of the hand, chambers of the heart, or wheels of a car - such that there can be a notion of a single one being missing, or whether, by contrast, the number of parts is indeterminate - e.g., cells in the skin of the hand, red cells in blood, or rubber molecules in the tread of the tire of the wheel of the car.
http://purl.obolibrary.org/obo/OBI_0001938	has value specification	http://purl.obolibrary.org/obo/BFO_0000051	has_part		A relation between an information content entity and a value specification that specifies its value.
http://purl.obolibrary.org/obo/RO_0002018	has component process	http://purl.obolibrary.org/obo/RO_0002180	has_component		w 'has process component' p if p and w are processes,  w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type.
http://purl.obolibrary.org/obo/RO_0019000	regulates characteristic	http://purl.obolibrary.org/obo/RO_0002410	causally related to		A relationship that holds between a process and a characteristic in which process (P) regulates characteristic (C) iff: P results in the existence of C OR affects the intensity or magnitude of C.
http://purl.obolibrary.org/obo/RO_0019001	positively regulates characteristic	http://purl.obolibrary.org/obo/RO_0019000	regulates characteristic		A relationship that holds between a process and a characteristic in which process (P) positively regulates characteristic (C) iff: P results in an increase in the intensity or magnitude of C.
http://purl.obolibrary.org/obo/RO_0019002	negatively regulates characteristic	http://purl.obolibrary.org/obo/RO_0019000	regulates characteristic		A relationship that holds between a process and a characteristic in which process (P) negatively regulates characteristic (C) iff: P results in a decrease in the intensity or magnitude of C.
http://purl.obolibrary.org/obo/RO_0002333	enabled by	http://purl.obolibrary.org/obo/RO_0002328	functionally related to		inverse of enables
http://purl.obolibrary.org/obo/RO_0002404	causally downstream of	http://purl.obolibrary.org/obo/RO_0002427	causally downstream of or within		inverse of upstream of
http://purl.obolibrary.org/obo/RO_0002412	immediately causally upstream of	http://purl.obolibrary.org/obo/RO_0002411	causally upstream of		p is immediately causally upstream of q iff p is causally upstream of q, and the end of p is coincident with the beginning of q.
http://purl.obolibrary.org/obo/RO_0002448	directly regulates activity of	http://purl.obolibrary.org/obo/RO_0011002	regulates activity of		The entity A, immediately upstream of the entity B, has an activity that regulates an activity performed by B. For example, A and B may be gene products and binding of B by A regulates the kinase activity of B.

A and B can be physically interacting but not necessarily. Immediately upstream means there are no intermediate entity between A and B.
http://purl.obolibrary.org/obo/RO_0002566	causally influences	http://purl.obolibrary.org/obo/RO_0002506	causal relation between entities		The entity or characteristic A is causally upstream of the entity or characteristic B, A having an effect on B. An entity corresponds to any biological type of entity as long as a mass is measurable. A characteristic corresponds to a particular specificity of an entity (e.g., phenotype, shape, size).
http://purl.obolibrary.org/obo/RO_0002263	acts upstream of	http://purl.obolibrary.org/obo/RO_0002264	acts upstream of or within		c acts upstream of p if and only if c enables some f that is involved in p' and p' occurs chronologically before p, is not part of p, and affects the execution of p. c is a material entity and f, p, p' are processes.
http://purl.obolibrary.org/obo/RO_0002304	causally upstream of, positive effect	http://purl.obolibrary.org/obo/RO_0004047	causally upstream of or within, positive effect		p is causally upstream of, positive effect q iff p is casually upstream of q, and the execution of p is required for the execution of q.
http://purl.obolibrary.org/obo/RO_0002305	causally upstream of, negative effect	http://purl.obolibrary.org/obo/RO_0004046	causally upstream of or within, negative effect		p is causally upstream of, negative effect q iff p is casually upstream of q, and the execution of p decreases the execution of q.
http://purl.obolibrary.org/obo/RO_0020337	has_constituent_monomer	http://purl.obolibrary.org/obo/RO_0002180	has_component		A relation that holds between a polymer and its constituent monomers. P has_constituent_monomer c if and only if P has_component multiple instances of c and each instance of c is covalently attached to another instance of c.
http://purl.obolibrary.org/obo/RO_0002131	location of	http://purl.obolibrary.org/obo/RO_0002323	mereotopologically related to		x overlaps y if and only if there exists some z such that x has part z and z part of y
http://purl.obolibrary.org/obo/RO_0000091	has disposition	http://purl.obolibrary.org/obo/RO_0000053	has characteristic		a relation between an independent continuant (the bearer) and a disposition, in which the disposition specifically depends on the bearer for its existence
http://purl.obolibrary.org/obo/RO_0000092	disposition of	http://purl.obolibrary.org/obo/RO_0000052	characteristic of		inverse of has disposition
http://purl.obolibrary.org/obo/RO_0011002	regulates activity of	http://purl.obolibrary.org/obo/RO_0002566	causally influences		The entity A has an activity that regulates an activity of the entity B. For example, A and B are gene products where the catalytic activity of A regulates the kinase activity of B.
http://purl.obolibrary.org/obo/RO_0002411	causally upstream of	http://purl.obolibrary.org/obo/RO_0002418	causally upstream of or within		p is causally upstream of q iff p is causally related to q, the end of p precedes the end of q, and p is not an occurrent part of q.
http://purl.obolibrary.org/obo/RO_0002211	regulates	http://purl.obolibrary.org/obo/RO_0002411	causally upstream of		p regulates q iff p is causally upstream of q, the execution of p is not constant and varies according to specific conditions, and p influences the rate or magnitude of execution of q due to an effect either on some enabler of q or some enabler of a part of q.
http://purl.obolibrary.org/obo/RO_0002212	negatively regulates	http://purl.obolibrary.org/obo/RO_0002211	regulates		p negatively regulates q iff p regulates q, and p decreases the rate or magnitude of execution of q.
http://purl.obolibrary.org/obo/RO_0002213	positively regulates	http://purl.obolibrary.org/obo/RO_0002211	regulates		p positively regulates q iff p regulates q, and p increases the rate or magnitude of execution of q.
http://purl.obolibrary.org/obo/pr#has_gene_template	has_gene_template	http://purl.obolibrary.org/obo/RO_0002330	genomically_related_to		See document https://docs.google.com/document/d/15iVMtMyYbQSlvUDgn2XUaDzpwkB0USZI for full definition.
http://purl.obolibrary.org/obo/RO_0002180	has_component	http://purl.obolibrary.org/obo/BFO_0000051	has_part		w 'has component' p if w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type.
http://purl.obolibrary.org/obo/RO_0002352	input of	http://purl.obolibrary.org/obo/RO_0002328	functionally related to		inverse of has input
http://purl.obolibrary.org/obo/RO_0002023	directly negatively regulated by	http://purl.obolibrary.org/obo/RO_0002022	directly regulated by		Process(P2) is directly negatively regulated by process(P1) iff: P1 negatively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2).  For example, if protein A has protein binding activity(P1) that targets protein B and this binding  negatively regulates the kinase activity (P2) of protein B then P2 directly negatively regulated by P1.
http://purl.obolibrary.org/obo/RO_0002024	directly positively regulated by	http://purl.obolibrary.org/obo/RO_0002022	directly regulated by		Process(P2) is directly postively regulated by process(P1) iff: P1 positively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2).  For example, if protein A has protein binding activity(P1) that targets protein B and this binding positively regulates the kinase activity (P2) of protein B then P2 is directly postively regulated by P1.
http://purl.obolibrary.org/obo/RO_0012011	indirectly causally upstream of	http://purl.obolibrary.org/obo/RO_0002411	causally upstream of		p is indirectly causally upstream of q iff p is causally upstream of q and there exists some process r such that p is causally upstream of r and r is causally upstream of q.
http://purl.obolibrary.org/obo/RO_0012012	indirectly regulates	http://purl.obolibrary.org/obo/RO_0012011	indirectly causally upstream of		p indirectly regulates q iff p is indirectly causally upstream of q and p regulates q.
http://purl.obolibrary.org/obo/RO_0002264	acts upstream of or within	http://purl.obolibrary.org/obo/RO_0002500	causal agent in process		c acts upstream of or within p if c is enables f, and f is causally upstream of or within p. c is a material entity and p is an process.
http://purl.obolibrary.org/obo/RO_0004031	enables subfunction	http://purl.obolibrary.org/obo/RO_0002328	functionally related to		Holds between an entity and an process P where the entity enables some larger compound process, and that larger process has-part P.
http://purl.obolibrary.org/obo/RO_0004034	acts upstream of, positive effect	http://purl.obolibrary.org/obo/RO_0004032	acts upstream of or within, positive effect		c 'acts upstream of, positive effect' p if c is enables f, and f is causally upstream of p, and the direction of f is positive
http://purl.obolibrary.org/obo/RO_0004035	acts upstream of, negative effect	http://purl.obolibrary.org/obo/RO_0004033	acts upstream of or within, negative effect		c 'acts upstream of, negative effect' p if c is enables f, and f is causally upstream of p, and the direction of f is negative
http://purl.obolibrary.org/obo/RO_0002334	regulated by	http://purl.obolibrary.org/obo/RO_0002427	causally downstream of or within		inverse of regulates
http://purl.obolibrary.org/obo/RO_0002335	negatively regulated by	http://purl.obolibrary.org/obo/RO_0002334	regulated by		inverse of negatively regulates
http://purl.obolibrary.org/obo/RO_0002336	positively regulated by	http://purl.obolibrary.org/obo/RO_0002334	regulated by		inverse of positively regulates
http://purl.obolibrary.org/obo/RO_0002427	causally downstream of or within	http://purl.obolibrary.org/obo/RO_0002501	causal relation between processes		inverse of causally upstream of or within
http://purl.obolibrary.org/obo/RO_0002500	causal agent in process	http://purl.obolibrary.org/obo/RO_0002595	causal relation between material entity and a process		A relationship between a material entity and a process where the material entity has some causal role that influences the process
http://purl.obolibrary.org/obo/RO_0002501	causal relation between processes	http://purl.obolibrary.org/obo/RO_0002410	causally related to		p is causally related to q if and only if p or any part of p and q or any part of q are linked by a chain of events where each event pair is one where the execution of p influences the execution of q. p may be upstream, downstream, part of, or a container of q.
http://purl.obolibrary.org/obo/RO_0002584	has part structure that is capable of	http://purl.obolibrary.org/obo/RO_0002595	causal relation between material entity and a process		s 'has part structure that is capable of' p if and only if there exists some part x such that s 'has part' x and x 'capable of' p
http://purl.obolibrary.org/obo/RO_0002595	causal relation between material entity and a process	http://purl.obolibrary.org/obo/RO_0002410	causally related to		A relationship that holds between a material entity and a process in which causality is involved, with either the material entity or some part of the material entity exerting some influence over the process, or the process influencing some aspect of the material entity.
http://purl.obolibrary.org/obo/RO_0002596	capable of regulating	http://purl.obolibrary.org/obo/RO_0002500	causal agent in process		Holds between c and p if and only if c is capable of some activity a, and a regulates p.
http://purl.obolibrary.org/obo/RO_0002597	capable of negatively regulating	http://purl.obolibrary.org/obo/RO_0002596	capable of regulating		Holds between c and p if and only if c is capable of some activity a, and a negatively regulates p.
http://purl.obolibrary.org/obo/RO_0002598	capable of positively regulating	http://purl.obolibrary.org/obo/RO_0002596	capable of regulating		Holds between c and p if and only if c is capable of some activity a, and a positively regulates p.
http://purl.obolibrary.org/obo/RO_0002608	process has causal agent	http://purl.obolibrary.org/obo/RO_0002410	causally related to		Inverse of 'causal agent in process'
http://purl.obolibrary.org/obo/RO_0002015	has positive regulatory component activity	http://purl.obolibrary.org/obo/RO_0002013	has regulatory component activity		A relationship that holds between a GO molecular function and a component of that molecular function that positively regulates the activity of the whole.  More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is positively regulated by B.
http://purl.obolibrary.org/obo/RO_0002013	has regulatory component activity	http://purl.obolibrary.org/obo/RO_0002017	has component activity		A 'has regulatory component activity' B if A and B are GO molecular functions (GO_0003674), A has_component B and A is regulated by B.
http://purl.obolibrary.org/obo/RO_0002014	has negative regulatory component activity	http://purl.obolibrary.org/obo/RO_0002013	has regulatory component activity		A relationship that holds between a GO molecular function and a component of that molecular function that negatively regulates the activity of the whole.  More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is negatively regulated by B.
http://purl.obolibrary.org/obo/RO_0009501	realized in response to	http://purl.obolibrary.org/obo/RO_0002410	causally related to		r 'realized in response to' s iff, r is a realizable (e.g. a plant trait such as responsivity to drought), s is an environmental stimulus (a process), and s directly causes the realization of r.
http://purl.obolibrary.org/obo/RO_0002428	involved in regulation of	http://purl.obolibrary.org/obo/RO_0002431	involved in or involved in regulation of		c involved in regulation of p if c is involved in some p' and p' regulates some p
http://purl.obolibrary.org/obo/RO_0002429	involved in positive regulation of	http://purl.obolibrary.org/obo/RO_0002428	involved in regulation of		c involved in regulation of p if c is involved in some p' and p' positively regulates some p
http://purl.obolibrary.org/obo/RO_0002430	involved in negative regulation of	http://purl.obolibrary.org/obo/RO_0002428	involved in regulation of		c involved in regulation of p if c is involved in some p' and p' negatively regulates some p
http://purl.obolibrary.org/obo/RO_0002578	directly regulates	http://purl.obolibrary.org/obo/RO_0002211	regulates		p directly regulates q iff p is immediately causally upstream of q and p regulates q.
http://purl.obolibrary.org/obo/RO_0002629	directly positively regulates	http://purl.obolibrary.org/obo/RO_0002578	directly regulates		p directly positively regulates q iff p is immediately causally upstream of q, and p positively regulates q.
http://purl.obolibrary.org/obo/RO_0002630	directly negatively regulates	http://purl.obolibrary.org/obo/RO_0002578	directly regulates		p directly negatively regulates q iff p is immediately causally upstream of q, and p negatively regulates q.
http://purl.obolibrary.org/obo/RO_0002087	immediately preceded by	http://purl.obolibrary.org/obo/BFO_0000062	preceded by	starts_at_end_of	
http://purl.obolibrary.org/obo/RO_0002090	immediately precedes	http://purl.obolibrary.org/obo/BFO_0000063	precedes	meets	
http://purl.obolibrary.org/obo/RO_0002447	phosphorylates	http://purl.obolibrary.org/obo/RO_0002436	molecularly interacts with	An interaction relation between x and y in which x catalyzes a reaction in which a phosphate group is added to y.	
http://purl.obolibrary.org/obo/RO_0002405	immediately causally downstream of	http://purl.obolibrary.org/obo/RO_0002404	causally downstream of		
http://purl.obolibrary.org/obo/RO_0002017	has component activity	http://purl.obolibrary.org/obo/RO_0002018	has component process		
http://purl.obolibrary.org/obo/IAO_0000039	has measurement unit label	http://purl.obolibrary.org/obo/BFO_0000051	has_part		
http://purl.obolibrary.org/obo/RO_0002559	causally influenced by	http://purl.obolibrary.org/obo/RO_0002506	causal relation between entities		
http://purl.obolibrary.org/obo/RO_0002563	interaction relation helper property	http://purl.obolibrary.org/obo/RO_0002464	helper property (not for use in curation)		
http://purl.obolibrary.org/obo/RO_0002564	molecular interaction relation helper property	http://purl.obolibrary.org/obo/RO_0002563	interaction relation helper property		
http://purl.obolibrary.org/obo/RO_0002481	is kinase activity	http://purl.obolibrary.org/obo/RO_0002564	molecular interaction relation helper property		
http://purl.obolibrary.org/obo/RO_0002086	ends after	http://purl.obolibrary.org/obo/RO_0002222	temporally related to		
http://purl.obolibrary.org/obo/RO_0004033	acts upstream of or within, negative effect	http://purl.obolibrary.org/obo/RO_0002264	acts upstream of or within		
http://purl.obolibrary.org/obo/RO_0004032	acts upstream of or within, positive effect	http://purl.obolibrary.org/obo/RO_0002264	acts upstream of or within		
http://purl.obolibrary.org/obo/RO_0002022	directly regulated by	http://purl.obolibrary.org/obo/RO_0002334	regulated by		
http://purl.obolibrary.org/obo/RO_0002506	causal relation between entities	http://purl.obolibrary.org/obo/RO_0002410	causally related to		
http://purl.obolibrary.org/obo/RO_0004046	causally upstream of or within, negative effect	http://purl.obolibrary.org/obo/RO_0002418	causally upstream of or within		
http://purl.obolibrary.org/obo/RO_0004047	causally upstream of or within, positive effect	http://purl.obolibrary.org/obo/RO_0002418	causally upstream of or within		
http://purl.obolibrary.org/obo/RO_0000053	has characteristic			is bearer of	Inverse of characteristic_of
http://purl.obolibrary.org/obo/RO_0000056	participates_in			participates_in	a relation between a continuant and a process, in which the continuant is somehow involved in the process
http://purl.obolibrary.org/obo/RO_0000057	has participant			has_participant	a relation between a process and a continuant, in which the continuant is somehow involved in the process
http://purl.obolibrary.org/obo/BFO_0000055	realizes				Paraphrase of elucidation: a relation between a process and a realizable entity, where there is some material entity that is bearer of the realizable entity and participates in the process, and the realizable entity comes to be realized in the course of the process
http://purl.obolibrary.org/obo/OBI_0001937	has specified numeric value				A relation between a value specification and a number that quantifies it.
http://purl.obolibrary.org/obo/RO_0017001	device utilizes material				X device utilizes material Y means X and Y are material entities, and X is capable of some process P that has input Y.
http://purl.obolibrary.org/obo/RO_0002434	interacts with				A relationship that holds between two entities in which the processes executed by the two entities are causally connected.
http://purl.obolibrary.org/obo/RO_0002323	mereotopologically related to				A mereological relationship or a topological relationship
http://purl.obolibrary.org/obo/RO_0002328	functionally related to				A grouping relationship for any relationship directly involving a function, or that holds because of a function of one of the related entities.
http://purl.obolibrary.org/obo/RO_0020105	is anatomical entity				This property only applies to anatomical entities.
http://purl.obolibrary.org/obo/RO_0002410	causally related to				relation that links two events, processes, states, or objects such that one event, process, state, or object (a cause) contributes to the production of another event, process, state, or object (an effect) where the cause is partly or wholly responsible for the effect, and the effect is partly or wholly dependent on the cause.
http://purl.obolibrary.org/obo/BFO_0000054	realized in			realized_in	
http://purl.obolibrary.org/obo/RO_0002464	helper property (not for use in curation)				
http://purl.obolibrary.org/obo/RO_0002222	temporally related to				
http://purl.obolibrary.org/obo/RO_0018033	is conjugate base of				
http://purl.obolibrary.org/obo/RO_0018034	is conjugate acid of				
http://purl.obolibrary.org/obo/RO_0018036	is tautomer of				
http://purl.obolibrary.org/obo/RO_0018037	is substituent group from				
http://purl.obolibrary.org/obo/RO_0018038	has functional parent				
http://purl.obolibrary.org/obo/RO_0018039	is enantiomer of				
http://purl.obolibrary.org/obo/RO_0018040	has parent hydride				
http://purl.obolibrary.org/obo/RO_0002353	output_of				
http://purl.obolibrary.org/obo/RO_0002502	depends on				
http://purl.obolibrary.org/obo/RO_0002330	genomically_related_to				
